Rho GTPase-activating protein

Overview


Name	Rho GTPase-activating protein
Smed ID	SMED30021616
Length (bp)	1749

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Rho GTPase-activating protein (SMED30021616) t-SNE clustered cells

Violin plots show distribution of expression levels for Rho GTPase-activating protein (SMED30021616) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Rho GTPase-activating protein (SMED30021616) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Rho GTPase-activating protein (SMED30021616) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30021616

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 13

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
intestinal phagocyte	SMED30021616	SMESG000027863.1	Contig2140	GPL15192	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30021616	SMESG000060252.1	Contig2140	GPL15192	PMID:23079596 Forsthoefel et al., 2012
pharynx	SMED30021616	SMESG000060252.1	dd_Smed_v4_3376_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
protonephridia	SMED30021616	SMESG000060252.1	dd_Smed_v4_3376_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30021616	SMESG000060252.1	dd_Smed_v4_3376_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30021616	SMESG000060252.1	dd_Smed_v4_3376_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30021616	SMESG000060252.1	dd_Smed_v4_3376_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30021616	SMESG000060252.1	dd_Smed_v4_3376_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30021616	SMESG000060252.1	dd_Smed_v4_3376_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cilated neuron	SMED30021616	SMESG000060252.1	dd_Smed_v4_3376_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30021616	SMESG000060252.1	Contig39636	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30021616	SMESG000060252.1	Contig39636	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
epidermis	SMED30021616	SMESG000060252.1	dd_Smed_v4_3376_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of Rho GTPase-activating protein vs. Ensembl Human
Match: ARHGAP8 (Rho GTPase activating protein 8 [Source:HGNC Symbol;Acc:HGNC:677])

HSP 1 Score: 249.98 bits (637), Expect = 3.062e-76
Identity = 144/375 (38.40%), Postives = 214/375 (57.07%), Query Frame = 3

Query:  318 DHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIW 1442
             H F D+A+  ++QVAGDDRFG++V+    CR+PP + ++  R   Y   TL Q+V NDY+++YFHYGL  +N P + ++ +AYK+ DR +KKNLK LY+VHPT+ +K + N L P  S K   K+I    L EL      DQ+VIP                  P   ++D+           KL S   G       +         LP  QFGV+LQ++K  +    +PPV+   + YLR + L  EG+FRRSAS   + EIQ+ Y+  + ++  +YGD H+ A +LKTFLR L +PL+TF+ +++I+ +  +++ + V  CRQI+   LP++NY VL+YL+ FL  V+  S  N M   N+A VF  +LIW
Sbjct:   11 SHPFYDVARHGILQVAGDDRFGRRVVTFSCCRMPPSHELDHQRLLEYLKYTLDQYVENDYTIVYFHYGLNSRNKPSLGWLQSAYKEFDRKYKKNLKALYVVHPTSFIKVLWNILKPLISHKFGKKVIYFNYLSELHEHLKYDQLVIP------------------PEVLRYDE-----------KLQSLHEGRTPPPTKT---PPPRPPLPTQQFGVSLQYLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILRS-LPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIW 352

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BLAST of Rho GTPase-activating protein vs. Ensembl Human
Match: PRR5-ARHGAP8 (PRR5-ARHGAP8 readthrough [Source:HGNC Symbol;Acc:HGNC:34512])

HSP 1 Score: 251.521 bits (641), Expect = 2.357e-75
Identity = 144/375 (38.40%), Postives = 214/375 (57.07%), Query Frame = 3

Query:  318 DHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIW 1442
             H F D+A+  ++QVAGDDRFG++V+    CR+PP + ++  R   Y   TL Q+V NDY+++YFHYGL  +N P + ++ +AYK+ DR +KKNLK LY+VHPT+ +K + N L P  S K   K+I    L EL      DQ+VIP                  P   ++D+           KL S   G       +         LP  QFGV+LQ++K  +    +PPV+   + YLR + L  EG+FRRSAS   + EIQ+ Y+  + ++  +YGD H+ A +LKTFLR L +PL+TF+ +++I+ +  +++ + V  CRQI+   LP++NY VL+YL+ FL  V+  S  N M   N+A VF  +LIW
Sbjct:  142 SHPFYDVARHGILQVAGDDRFGRRVVTFSCCRMPPSHELDHQRLLEYLKYTLDQYVENDYTIVYFHYGLNSRNKPSLGWLQSAYKEFDRKYKKNLKALYVVHPTSFIKVLWNILKPLISHKFGKKVIYFNYLSELHEHLKYDQLVIP------------------PEVLRYDE-----------KLQSLHEGRTPPPTKT---PPPRPPLPTQQFGVSLQYLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILRS-LPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIW 483

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BLAST of Rho GTPase-activating protein vs. Ensembl Human
Match: ARHGAP1 (Rho GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:673])

HSP 1 Score: 245.358 bits (625), Expect = 1.899e-74
Identity = 139/378 (36.77%), Postives = 216/378 (57.14%), Query Frame = 3

Query:  318 DHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCH-VPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSR 1448
            D  + DIA+  +V+VAGDD++G+K+I+  ACR+PP + ++  +   Y   TL Q+V +DY+L+Y H+GLT  N P + ++ +AY++ DR +KKN+K LYIVHPT  +K ++    P  S K   KI  V  L EL     L+Q+ IP                      K+DDF    +K       SP++                  LP  QFGV+LQH+++ + +   +P V+ + + YL++  L  EGIFRRSA+   + E+Q+KY++   +D  +Y + HL A +LKTFLR L EPL+TF+L+  ++   N+     V    Q V   LP+ NY VL++L  FL++++ HSD+N MT  N+A VF P+L+W++
Sbjct:   61 DDPYYDIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKHTLDQYVESDYTLLYLHHGLTSDNKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPLISFKFGQKIFYVNYLSELSEHVKLEQLGIPR------------------QVLKYDDFLKSTQK-------SPATAPKPMPPRP--------PLPNQQFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQ-VLQTLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWAK 404

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BLAST of Rho GTPase-activating protein vs. Ensembl Human
Match: PRR5-ARHGAP8 (PRR5-ARHGAP8 readthrough [Source:HGNC Symbol;Acc:HGNC:34512])

HSP 1 Score: 242.276 bits (617), Expect = 1.457e-72
Identity = 145/392 (36.99%), Postives = 215/392 (54.85%), Query Frame = 3

Query:  318 DHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNL-----------------KTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIW 1442
             H F D+A+  ++QVAGDDRFG++V+    CR+PP + ++  R   Y   TL Q+V NDY+++YFHYGL  +N P + ++ +AYK+ DR +KKNLK LY+VHPT+ +K + N L P  S K   K+I    L EL      DQ+VIP                  P   ++D+           KL S   G       +         LP  QFGV+LQ++K  +    +PPV+   + YLR + L  EG+FRRSAS   + EIQ+ Y+  + ++  +YGD H+ A +LKTFLR L +PL+TF+ +++I+ + +L                 ++ + V  CRQI+   LP++NY VL+YL+ FL  V+  S  N M   N+A VF  +LIW
Sbjct:   65 SHPFYDVARHGILQVAGDDRFGRRVVTFSCCRMPPSHELDHQRLLEYLKYTLDQYVENDYTIVYFHYGLNSRNKPSLGWLQSAYKEFDRKYKKNLKALYVVHPTSFIKVLWNILKPLISHKFGKKVIYFNYLSELHEHLKYDQLVIP------------------PEVLRYDE-----------KLQSLHEGRTPPPTKT---PPPRPPLPTQQFGVSLQYLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITSLPLAPLELSREPHALPGVESSLRVTGCRQILRS-LPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIW 423

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BLAST of Rho GTPase-activating protein vs. Ensembl Human
Match: ARHGAP8 (Rho GTPase activating protein 8 [Source:HGNC Symbol;Acc:HGNC:677])

HSP 1 Score: 233.802 bits (595), Expect = 8.792e-70
Identity = 144/406 (35.47%), Postives = 214/406 (52.71%), Query Frame = 3

Query:  318 DHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRD-------------------------------FKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIW 1442
             H F D+A+  ++QVAGDDRFG++V+    CR+PP + ++  R   Y   TL Q+V NDY+++YFHYGL  +N P + ++ +AYK+ DR                                +KKNLK LY+VHPT+ +K + N L P  S K   K+I    L EL      DQ+VIP                  P   ++D+           KL S   G       +         LP  QFGV+LQ++K  +    +PPV+   + YLR + L  EG+FRRSAS   + EIQ+ Y+  + ++  +YGD H+ A +LKTFLR L +PL+TF+ +++I+ +  +++ + V  CRQI+   LP++NY VL+YL+ FL  V+  S  N M   N+A VF  +LIW
Sbjct:   11 SHPFYDVARHGILQVAGDDRFGRRVVTFSCCRMPPSHELDHQRLLEYLKYTLDQYVENDYTIVYFHYGLNSRNKPSLGWLQSAYKEFDRKDGDLTMWPRLVSNSKLKRSSHLSLPKYWDYRYKKNLKALYVVHPTSFIKVLWNILKPLISHKFGKKVIYFNYLSELHEHLKYDQLVIP------------------PEVLRYDE-----------KLQSLHEGRTPPPTKT---PPPRPPLPTQQFGVSLQYLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILRS-LPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIW 383

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BLAST of Rho GTPase-activating protein vs. Ensembl Celegans
Match: rga-1 (Rho GTPase Activating protein [Source:UniProtKB/TrEMBL;Acc:Q23130])

HSP 1 Score: 202.601 bits (514), Expect = 1.170e-58
Identity = 129/381 (33.86%), Postives = 199/381 (52.23%), Query Frame = 3

Query:  327 FSDIAKLNVVQVAGD-DRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDL--------SEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIW 1442
            F+DI+   ++QV  D DR G+ ++++YA R+P    I+  R   Y V+ + + V  DY+++YFHYGL   N P ++++  AYKQ+DR FKKNLK LY+VHPT  ++ I +    F S+K ++K   V  + ELE+   + ++ +P  I                             +DHD             +Q + P T   + LP  QFGV L+ I   H   ++PP+++Q I YL +  L  EG+FR+SA+   +  +Q + +  E ID         +EY     A+ LLKTF RSL EPL T  L+ ++  L  +         ++ V  +LP  NY +LK +I+FL  VAE+S  N+MT  N++ VF P+L W
Sbjct:   73 FNDISAHEIIQVIADGDRVGRPIVVVYAYRLPSSKEIDHARLLQYLVQIIDKIVDQDYTIVYFHYGLRSHNKPPVRWLFQAYKQLDRRFKKNLKALYVVHPTRFIRIIFSLFKGFISSKFENKFHYVMCIDELENALSVARLNLPSPI-----------------------------RDHDKSFS---------TQSNRPETPPAQPLPTQQFGVPLEFILS-HCGGNIPPIVDQLIEYLEAHALTMEGVFRKSANIGSIKRLQDRINKGEKIDFENDPEYKDNEYVASLHASVLLKTFFRSLGEPLTTNRLYPKLAALSEVSKTEKSAAVKEFV-KLLPRENYILLKTVIKFLTRVAENSKVNLMTANNLSVVFGPNLTW 413

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BLAST of Rho GTPase-activating protein vs. Ensembl Celegans
Match: rga-1 (Rho GTPase Activating protein [Source:UniProtKB/TrEMBL;Acc:Q23130])

HSP 1 Score: 116.316 bits (290), Expect = 3.194e-29
Identity = 70/187 (37.43%), Postives = 103/187 (55.08%), Query Frame = 3

Query:  906 SQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLS---EYGDPHL-----AACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIW 1442
            +Q + P T   + LP  QFGV L+ I   H   ++PP+++Q I YL +  L  EG+FR+SA+   +  +Q + +  E ID     EY D        A+ LLKTF RSL EPL T  L+ ++  L  +         ++ V  +LP  NY +LK +I+FL  VAE+S  N+MT  N++ VF P+L W
Sbjct:   30 TQSNRPETPPAQPLPTQQFGVPLEFILS-HCGGNIPPIVDQLIEYLEAHALTMEGVFRKSANIGSIKRLQDRINKGEKIDFENDPEYKDNEYVASLHASVLLKTFFRSLGEPLTTNRLYPKLAALSEVSKTEKSAAVKEFV-KLLPRENYILLKTVIKFLTRVAENSKVNLMTANNLSVVFGPNLTW 214

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Query:  906 SQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLS---EYGDPHL-----AACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIW 1442
            +Q + P T   + LP  QFGV L+ I   H   ++PP+++Q I YL +  L  EG+FR+SA+   +  +Q + +  E ID     EY D        A+ LLKTF RSL EPL T  L+ ++  L  +         ++ V  +LP  NY +LK +I+FL  VAE+S  N+MT  N++ VF P+L W
Sbjct:   30 TQSNRPETPPAQPLPTQQFGVPLEFILS-HCGGNIPPIVDQLIEYLEAHALTMEGVFRKSANIGSIKRLQDRINKGEKIDFENDPEYKDNEYVASLHASVLLKTFFRSLGEPLTTNRLYPKLAALSEVSKTEKSAAVKEFV-KLLPRENYILLKTVIKFLTRVAENSKVNLMTANNLSVVFGPNLTW 214

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Query:  906 SQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLS---EYGDPHL-----AACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIW 1442
            +Q + P T   + LP  QFGV L+ I   H   ++PP+++Q I YL +  L  EG+FR+SA+   +  +Q + +  E ID     EY D        A+ LLKTF RSL EPL T  L+ ++  L  +         ++ V  +LP  NY +LK +I+FL  VAE+S  N+MT  N++ VF P+L W
Sbjct:   30 TQSNRPETPPAQPLPTQQFGVPLEFILS-HCGGNIPPIVDQLIEYLEAHALTMEGVFRKSANIGSIKRLQDRINKGEKIDFENDPEYKDNEYVASLHASVLLKTFFRSLGEPLTTNRLYPKLAALSEVSKTEKSAAVKEFV-KLLPRENYILLKTVIKFLTRVAENSKVNLMTANNLSVVFGPNLTW 214

[Close]

Query:  906 SQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLS---EYGDPHL-----AACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIW 1442
            +Q + P T   + LP  QFGV L+ I   H   ++PP+++Q I YL +  L  EG+FR+SA+   +  +Q + +  E ID     EY D        A+ LLKTF RSL EPL T  L+ ++  L  +         ++ V  +LP  NY +LK +I+FL  VAE+S  N+MT  N++ VF P+L W
Sbjct:   30 TQSNRPETPPAQPLPTQQFGVPLEFILS-HCGGNIPPIVDQLIEYLEAHALTMEGVFRKSANIGSIKRLQDRINKGEKIDFENDPEYKDNEYVASLHASVLLKTFFRSLGEPLTTNRLYPKLAALSEVSKTEKSAAVKEFV-KLLPRENYILLKTVIKFLTRVAENSKVNLMTANNLSVVFGPNLTW 214

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BLAST of Rho GTPase-activating protein vs. Ensembl Fly
Match: RhoGAP68F (gene:FBgn0036257 transcript:FBtr0334091)

HSP 1 Score: 198.749 bits (504), Expect = 2.457e-57
Identity = 125/364 (34.34%), Postives = 200/364 (54.95%), Query Frame = 3

Query:  366 GDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKC--HVPPVMEQCIMYLR-SECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSR 1448
            G D+ G+ +  IYA R P      L+ F    +K ++ FV NDY L+YFH GL + N P  +F+ N+YK++DR+F+KNLK LY+VHPT  ++ I N   PF S K + K++ +  L EL     L+++ +P+ I   D   + +  S++P T                    PSS  N   Q        +K     QFGV L+ I   +S C   +PP++ +C+  L  +  ++ EGIFRRS +  +++ ++++ +  E +DL    + H+ A LLK+FLR L EPL+TFEL++++    +   +       Q++ + LP+ NY + KY++EFL+ V +  D N MT  N+A VF P+ +WSR
Sbjct:   48 GTDKQGRHIFGIYASRFP--EKSQLEGFVREIIKEIEPFVENDYILVYFHQGLKEDNKPSAQFLWNSYKELDRNFRKNLKTLYVVHPTWFIRVIWNFFSPFISDKFRKKLVYISSLDELRQALGLNKLKLPDNICDLD---DKLNPSRKPST------------------PPPSSNINASRQQQ------HKMATTHQFGVPLKFIVM-NSPCLNSIPPIVRKCVDSLSITGVIDTEGIFRRSGNHSEIMALKERVNRGEDVDLKSV-NVHVIAGLLKSFLRDLAEPLLTFELYEDVTGFLDWPKEERSRNVTQLIREKLPEENYELFKYIVEFLVRVMDCEDLNKMTSSNLAIVFGPNFLWSR 380

[Close]

BLAST of Rho GTPase-activating protein vs. Ensembl Fly
Match: RhoGAP68F (gene:FBgn0036257 transcript:FBtr0334093)

HSP 1 Score: 198.364 bits (503), Expect = 1.203e-56
Identity = 125/364 (34.34%), Postives = 200/364 (54.95%), Query Frame = 3

Query:  366 GDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKC--HVPPVMEQCIMYLR-SECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSR 1448
            G D+ G+ +  IYA R P      L+ F    +K ++ FV NDY L+YFH GL + N P  +F+ N+YK++DR+F+KNLK LY+VHPT  ++ I N   PF S K + K++ +  L EL     L+++ +P+ I   D   + +  S++P T                    PSS  N   Q        +K     QFGV L+ I   +S C   +PP++ +C+  L  +  ++ EGIFRRS +  +++ ++++ +  E +DL    + H+ A LLK+FLR L EPL+TFEL++++    +   +       Q++ + LP+ NY + KY++EFL+ V +  D N MT  N+A VF P+ +WSR
Sbjct:  104 GTDKQGRHIFGIYASRFP--EKSQLEGFVREIIKEIEPFVENDYILVYFHQGLKEDNKPSAQFLWNSYKELDRNFRKNLKTLYVVHPTWFIRVIWNFFSPFISDKFRKKLVYISSLDELRQALGLNKLKLPDNICDLD---DKLNPSRKPST------------------PPPSSNINASRQQQ------HKMATTHQFGVPLKFIVM-NSPCLNSIPPIVRKCVDSLSITGVIDTEGIFRRSGNHSEIMALKERVNRGEDVDLKSV-NVHVIAGLLKSFLRDLAEPLLTFELYEDVTGFLDWPKEERSRNVTQLIREKLPEENYELFKYIVEFLVRVMDCEDLNKMTSSNLAIVFGPNFLWSR 436

[Close]

BLAST of Rho GTPase-activating protein vs. Ensembl Fly
Match: RhoGAP68F (gene:FBgn0036257 transcript:FBtr0075997)

HSP 1 Score: 198.364 bits (503), Expect = 1.295e-56
Identity = 125/364 (34.34%), Postives = 200/364 (54.95%), Query Frame = 3

Query:  366 GDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKC--HVPPVMEQCIMYLR-SECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSR 1448
            G D+ G+ +  IYA R P      L+ F    +K ++ FV NDY L+YFH GL + N P  +F+ N+YK++DR+F+KNLK LY+VHPT  ++ I N   PF S K + K++ +  L EL     L+++ +P+ I   D   + +  S++P T                    PSS  N   Q        +K     QFGV L+ I   +S C   +PP++ +C+  L  +  ++ EGIFRRS +  +++ ++++ +  E +DL    + H+ A LLK+FLR L EPL+TFEL++++    +   +       Q++ + LP+ NY + KY++EFL+ V +  D N MT  N+A VF P+ +WSR
Sbjct:  105 GTDKQGRHIFGIYASRFP--EKSQLEGFVREIIKEIEPFVENDYILVYFHQGLKEDNKPSAQFLWNSYKELDRNFRKNLKTLYVVHPTWFIRVIWNFFSPFISDKFRKKLVYISSLDELRQALGLNKLKLPDNICDLD---DKLNPSRKPST------------------PPPSSNINASRQQQ------HKMATTHQFGVPLKFI-VMNSPCLNSIPPIVRKCVDSLSITGVIDTEGIFRRSGNHSEIMALKERVNRGEDVDLKSV-NVHVIAGLLKSFLRDLAEPLLTFELYEDVTGFLDWPKEERSRNVTQLIREKLPEENYELFKYIVEFLVRVMDCEDLNKMTSSNLAIVFGPNFLWSR 437

[Close]

BLAST of Rho GTPase-activating protein vs. Ensembl Fly
Match: RhoGAP68F (gene:FBgn0036257 transcript:FBtr0334092)

HSP 1 Score: 198.364 bits (503), Expect = 1.295e-56
Identity = 125/364 (34.34%), Postives = 200/364 (54.95%), Query Frame = 3

Query:  366 GDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKC--HVPPVMEQCIMYLR-SECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSR 1448
            G D+ G+ +  IYA R P      L+ F    +K ++ FV NDY L+YFH GL + N P  +F+ N+YK++DR+F+KNLK LY+VHPT  ++ I N   PF S K + K++ +  L EL     L+++ +P+ I   D   + +  S++P T                    PSS  N   Q        +K     QFGV L+ I   +S C   +PP++ +C+  L  +  ++ EGIFRRS +  +++ ++++ +  E +DL    + H+ A LLK+FLR L EPL+TFEL++++    +   +       Q++ + LP+ NY + KY++EFL+ V +  D N MT  N+A VF P+ +WSR
Sbjct:  105 GTDKQGRHIFGIYASRFP--EKSQLEGFVREIIKEIEPFVENDYILVYFHQGLKEDNKPSAQFLWNSYKELDRNFRKNLKTLYVVHPTWFIRVIWNFFSPFISDKFRKKLVYISSLDELRQALGLNKLKLPDNICDLD---DKLNPSRKPST------------------PPPSSNINASRQQQ------HKMATTHQFGVPLKFI-VMNSPCLNSIPPIVRKCVDSLSITGVIDTEGIFRRSGNHSEIMALKERVNRGEDVDLKSV-NVHVIAGLLKSFLRDLAEPLLTFELYEDVTGFLDWPKEERSRNVTQLIREKLPEENYELFKYIVEFLVRVMDCEDLNKMTSSNLAIVFGPNFLWSR 437

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BLAST of Rho GTPase-activating protein vs. Ensembl Fly
Match: RhoGAP92B (gene:FBgn0038747 transcript:FBtr0344352)

HSP 1 Score: 84.3445 bits (207), Expect = 7.086e-17
Identity = 51/170 (30.00%), Postives = 89/170 (52.35%), Query Frame = 3

Query:  951 ESQFGVTL-QHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLS---EYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSR 1448
            +S+FG +L +H+   + +     ++E C   L    LE EG+ R   +  KL  ++   +  +H+      +Y DPH+   +LK +LR L EPL+T+ L+ + I++    ++       + +   LP  NY  L+YL  FL  V + S  N M+ QN+A V +P+++W R
Sbjct:   49 KSRFGTSLKEHLTSTNREISY--IVELCCCCLLEHGLEEEGLLRVGCASTKLRRMKHALEA-QHVKTPLPLDYQDPHVIGSILKLYLRELPEPLLTYNLYKDFIRIAERHSEAERKTEIKAILTKLPKENYANLRYLTRFLSIVQQRSALNKMSSQNLAIVMSPNMLWPR 215

[Close]

BLAST of Rho GTPase-activating protein vs. Ensembl Zebrafish
Match: arhgap1 (Rho GTPase activating protein 1 [Source:ZFIN;Acc:ZDB-GENE-050417-305])

HSP 1 Score: 236.884 bits (603), Expect = 1.844e-71
Identity = 142/385 (36.88%), Postives = 219/385 (56.88%), Query Frame = 3

Query:  300 TSQDMIDHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIPEIIKT-QDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCH-VPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSR 1448
            TS    D  F DIA+  +V+VAGDD FG+KVI+  ACR+PP + ++  +   Y  +TL ++V +DY+LIYFH+GLT +N P + ++ +AY++ DR +KKN+K LYIVHPT  ++ I+    P  S K   KI  +  L ELE     DQ+VIP  ++   D+ R S+  S  P                                +S P +     LP  QFGV+L  +K   +    +P VM   I +L    L+ EGIFRRSA+   + +++ KY+  E ++ S+  D HLAA +LK FLR L EPL+T++L+++I+  HN+  +   +  + ++   LPD NY  L++L++FL +V+  S+ N MT  N+A VF P+L+W++
Sbjct:   55 TSHLPWDDPFYDIARHQIVEVAGDDNFGRKVIVFNACRMPPQHQLDHHKLLMYLKQTLDKYVESDYTLIYFHHGLTSENKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIRTILILFKPIISFKFGRKINYINYLSELEEIVKCDQLVIPNRVREYDDKIRLSLKPSVVP------------------------------GPISPPRSP---PLPFQQFGVSLTTLKHRAADSEGIPLVMRDTIGFLLENGLQTEGIFRRSANVSLVKDVKAKYNSGEEVNFSQLEDVHLAAVILKMFLRELPEPLLTYQLYNDIVNFHNVDIESQAERIQNMLMS-LPDENYASLRFLVQFLAQVSAESEINKMTNANLAVVFGPNLLWAQ 405

[Close]

Query:  300 TSQDMIDHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIPEIIKT-QDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCH-VPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSR 1448
            TS    D  F DIA+  +V+VAGDD FG+KVI+  ACR+PP + ++  +   Y  +TL ++V +DY+LIYFH+GLT +N P + ++ +AY++ DR +KKN+K LYIVHPT  ++ I+    P  S K   KI  +  L ELE     DQ+VIP  ++   D+ R S+  S  P                                +S P +     LP  QFGV+L  +K   +    +P VM   I +L    L+ EGIFRRSA+   + +++ KY+  E ++ S+  D HLAA +LK FLR L EPL+T++L+++I+  HN+  +   +  + ++   LPD NY  L++L++FL +V+  S+ N MT  N+A VF P+L+W++
Sbjct:   55 TSHLPWDDPFYDIARHQIVEVAGDDNFGRKVIVFNACRMPPQHQLDHHKLLMYLKQTLDKYVESDYTLIYFHHGLTSENKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIRTILILFKPIISFKFGRKINYINYLSELEEIVKCDQLVIPNRVREYDDKIRLSLKPSVVP------------------------------GPISPPRSP---PLPFQQFGVSLTTLKHRAADSEGIPLVMRDTIGFLLENGLQTEGIFRRSANVSLVKDVKAKYNSGEEVNFSQLEDVHLAAVILKMFLRELPEPLLTYQLYNDIVNFHNVDIESQAERIQNMLMS-LPDENYASLRFLVQFLAQVSAESEINKMTNANLAVVFGPNLLWAQ 405

[Close]

BLAST of Rho GTPase-activating protein vs. Ensembl Zebrafish
Match: arhgap17b (Rho GTPase activating protein 17b [Source:ZFIN;Acc:ZDB-GENE-080220-26])

HSP 1 Score: 113.235 bits (282), Expect = 8.453e-26
Identity = 61/166 (36.75%), Postives = 95/166 (57.23%), Query Frame = 3

Query:  960 FGVTLQ-HIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSRHE 1454
            FG  L+ H+K+   +  +P  +E C+M L    ++ EG+FR +A   KL +++   D +       Y DPH  A  LK++LR L EPLM+++L++E I+  N+           +VCDMLP  N    +YL++FL ++A  SD N MT  NIA V  P+L+W++ E
Sbjct:  254 FGTALEEHLKRTGREVALP--IEACVMMLLETGMQEEGLFRIAAGASKLKKLKAALDCSTSQLEEFYSDPHAVAGALKSYLRELPEPLMSYQLYEEWIQASNISDPDKRLQALWVVCDMLPKANKTNFRYLVKFLAKLALESDVNKMTASNIAIVLGPNLLWAKTE 417

[Close]

BLAST of Rho GTPase-activating protein vs. Ensembl Zebrafish
Match: arhgap17a (Rho GTPase activating protein 17a [Source:ZFIN;Acc:ZDB-GENE-050417-56])

HSP 1 Score: 112.849 bits (281), Expect = 1.376e-25
Identity = 61/166 (36.75%), Postives = 94/166 (56.63%), Query Frame = 3

Query:  960 FGVTL-QHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSRHE 1454
            FG  L +H+K+   +  +P  +E C+M L    ++ EG+FR +A   KL +++   D +       Y DPH  A  LK++LR L EPLMT++L+DE I+  N+           + CD LP  N    +YL++FL ++A+ SD N MT  NIA V  P+L+W++ E
Sbjct:  253 FGTALDEHLKRSSREIALP--IEACVMMLLETGMKEEGLFRIAAGASKLKKLKAALDCSTSQLEEFYSDPHAVAGALKSYLRELPEPLMTYQLYDEWIQASNVPDPDKRLQALWVTCDQLPKNNKANFRYLVKFLAKLAQESDVNKMTPSNIAIVLGPNLLWAKTE 416

[Close]

BLAST of Rho GTPase-activating protein vs. Ensembl Zebrafish
Match: arhgap17a (Rho GTPase activating protein 17a [Source:ZFIN;Acc:ZDB-GENE-050417-56])

HSP 1 Score: 112.464 bits (280), Expect = 1.682e-25
Identity = 61/166 (36.75%), Postives = 94/166 (56.63%), Query Frame = 3

Query:  960 FGVTL-QHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSRHE 1454
            FG  L +H+K+   +  +P  +E C+M L    ++ EG+FR +A   KL +++   D +       Y DPH  A  LK++LR L EPLMT++L+DE I+  N+           + CD LP  N    +YL++FL ++A+ SD N MT  NIA V  P+L+W++ E
Sbjct:  233 FGTALDEHLKRSSREIALP--IEACVMMLLETGMKEEGLFRIAAGASKLKKLKAALDCSTSQLEEFYSDPHAVAGALKSYLRELPEPLMTYQLYDEWIQASNVPDPDKRLQALWVTCDQLPKNNKANFRYLVKFLAKLAQESDVNKMTPSNIAIVLGPNLLWAKTE 396

[Close]

BLAST of Rho GTPase-activating protein vs. Ensembl Xenopus
Match: ublcp1 (ubiquitin like domain containing CTD phosphatase 1 [Source:Xenbase;Acc:XB-GENE-5892709])

HSP 1 Score: 226.098 bits (575), Expect = 3.506e-67
Identity = 130/380 (34.21%), Postives = 210/380 (55.26%), Query Frame = 3

Query:  318 DHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIP-EIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKC-HVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHN-LKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSR 1448
            D  + DIA   +V+VAGDD++G+K+++  ACR+PP + I+  +   Y   TL Q+V +DY+L+Y H+GLT +N P + ++ +AY++ DR +KKN+K LYIVHPT  +K ++    P  S K   KI     L +LE    ++Q+ IP +++K  D  R+++  S              N+                                  QFG++L H+K+ H +   +P V+   + +L+   L  EGIFRRSA    + E+Q+KY++   +   +Y D HL A +LKTFLR L EPL+T+ L+  ++   + L  +  ++   QI+   LP  NY VL++L  FL+EV+ H+++N MT  N+A VF P+L+W +
Sbjct:   62 DDPYYDIAWRQIVEVAGDDKYGRKIVVFSACRLPPCHEIDHVKLLQYLKHTLDQYVESDYTLVYLHHGLTSENKPSLGWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPIISFKFGRKIFYANYLSDLEEHMKVEQLGIPKQVLKYDDLIRSNLKTSAATQKPGPPRPPLPNQ----------------------------------QFGISLLHLKEKHPENDKIPLVVRDTVAFLQENALSTEGIFRRSARTQIVREVQQKYNMGVQVTFQQYDDVHLPAVILKTFLRELPEPLLTYNLYSFVVDFSSKLAQEQKIESTLQIL-QTLPKENYDVLQFLTAFLVEVSSHNEQNKMTTTNLAVVFGPNLLWVK 406

[Close]

BLAST of Rho GTPase-activating protein vs. Ensembl Xenopus
Match: ublcp1 (ubiquitin like domain containing CTD phosphatase 1 [Source:Xenbase;Acc:XB-GENE-5892709])

HSP 1 Score: 226.098 bits (575), Expect = 4.116e-67
Identity = 130/379 (34.30%), Postives = 209/379 (55.15%), Query Frame = 3

Query:  318 DHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIP-EIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKC-HVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSR 1448
            D  + DIA   +V+VAGDD++G+K+++  ACR+PP + I+  +   Y   TL Q+V +DY+L+Y H+GLT +N P + ++ +AY++ DR +KKN+K LYIVHPT  +K ++    P  S K   KI     L +LE    ++Q+ IP +++K  D  R+++  S              N+                                  QFG++L H+K+ H +   +P V+   + +L+   L  EGIFRRSA    + E+Q+KY++   +   +Y D HL A +LKTFLR L EPL+T+ L+  ++     K +  ++   QI+   LP  NY VL++L  FL+EV+ H+++N MT  N+A VF P+L+W +
Sbjct:   70 DDPYYDIAWRQIVEVAGDDKYGRKIVVFSACRLPPCHEIDHVKLLQYLKHTLDQYVESDYTLVYLHHGLTSENKPSLGWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPIISFKFGRKIFYANYLSDLEEHMKVEQLGIPKQVLKYDDLIRSNLKTSAATQKPGPPRPPLPNQ----------------------------------QFGISLLHLKEKHPENDKIPLVVRDTVAFLQENALSTEGIFRRSARTQIVREVQQKYNMGVQVTFQQYDDVHLPAVILKTFLRELPEPLLTYNLYSFVVDFS--KQEQKIESTLQIL-QTLPKENYDVLQFLTAFLVEVSSHNEQNKMTTTNLAVVFGPNLLWVK 411

[Close]

BLAST of Rho GTPase-activating protein vs. Ensembl Xenopus
Match: ublcp1 (ubiquitin like domain containing CTD phosphatase 1 [Source:Xenbase;Acc:XB-GENE-5892709])

HSP 1 Score: 225.713 bits (574), Expect = 4.725e-67
Identity = 130/379 (34.30%), Postives = 209/379 (55.15%), Query Frame = 3

Query:  318 DHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIP-EIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKC-HVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSR 1448
            D  + DIA   +V+VAGDD++G+K+++  ACR+PP + I+  +   Y   TL Q+V +DY+L+Y H+GLT +N P + ++ +AY++ DR +KKN+K LYIVHPT  +K ++    P  S K   KI     L +LE    ++Q+ IP +++K  D  R+++  S              N+                                  QFG++L H+K+ H +   +P V+   + +L+   L  EGIFRRSA    + E+Q+KY++   +   +Y D HL A +LKTFLR L EPL+T+ L+  ++     K +  ++   QI+   LP  NY VL++L  FL+EV+ H+++N MT  N+A VF P+L+W +
Sbjct:   62 DDPYYDIAWRQIVEVAGDDKYGRKIVVFSACRLPPCHEIDHVKLLQYLKHTLDQYVESDYTLVYLHHGLTSENKPSLGWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPIISFKFGRKIFYANYLSDLEEHMKVEQLGIPKQVLKYDDLIRSNLKTSAATQKPGPPRPPLPNQ----------------------------------QFGISLLHLKEKHPENDKIPLVVRDTVAFLQENALSTEGIFRRSARTQIVREVQQKYNMGVQVTFQQYDDVHLPAVILKTFLRELPEPLLTYNLYSFVVDFS--KQEQKIESTLQIL-QTLPKENYDVLQFLTAFLVEVSSHNEQNKMTTTNLAVVFGPNLLWVK 403

[Close]

BLAST of Rho GTPase-activating protein vs. Ensembl Xenopus
Match: ublcp1 (ubiquitin like domain containing CTD phosphatase 1 [Source:Xenbase;Acc:XB-GENE-5892709])

HSP 1 Score: 218.009 bits (554), Expect = 5.038e-64
Identity = 129/383 (33.68%), Postives = 209/383 (54.57%), Query Frame = 3

Query:  318 DHEFSDIAKLNVVQVA----GDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIP-EIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKC-HVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSR 1448
            D  + DIA   +V+VA     DD++G+K+++  ACR+PP + I+  +   Y   TL Q+V +DY+L+Y H+GLT +N P + ++ +AY++ DR +KKN+K LYIVHPT  +K ++    P  S K   KI     L +LE    ++Q+ IP +++K  D  R+++  S              N+                                  QFG++L H+K+ H +   +P V+   + +L+   L  EGIFRRSA    + E+Q+KY++   +   +Y D HL A +LKTFLR L EPL+T+ L+  ++   + K +  ++   QI+   LP  NY VL++L  FL+EV+ H+++N MT  N+A VF P+L+W +
Sbjct:   62 DDPYYDIAWRQIVEVARNLPSDDKYGRKIVVFSACRLPPCHEIDHVKLLQYLKHTLDQYVESDYTLVYLHHGLTSENKPSLGWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPIISFKFGRKIFYANYLSDLEEHMKVEQLGIPKQVLKYDDLIRSNLKTSAATQKPGPPRPPLPNQ----------------------------------QFGISLLHLKEKHPENDKIPLVVRDTVAFLQENALSTEGIFRRSARTQIVREVQQKYNMGVQVTFQQYDDVHLPAVILKTFLRELPEPLLTYNLYSFVVDFSS-KLEQKIESTLQIL-QTLPKENYDVLQFLTAFLVEVSSHNEQNKMTTTNLAVVFGPNLLWVK 408

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BLAST of Rho GTPase-activating protein vs. Ensembl Xenopus
Match: ARHGAP17 (Rho GTPase activating protein 17 [Source:NCBI gene;Acc:549590])

HSP 1 Score: 114.775 bits (286), Expect = 4.692e-26
Identity = 68/187 (36.36%), Postives = 99/187 (52.94%), Query Frame = 3

Query:  930 SFYKALPESQ-----------FGVTLQ-HIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSRHE 1454
            +  KALPE Q           FG  L+ H+K+   +  +P  +E C+M L    ++ EG+FR +A   KL +++   D +       Y DPH  A  LK++LR L EPLMTF L++E     N+           +VC  LP  N    +YL++FL +++ HSD N MT  NIA V  P+L+W+RHE
Sbjct:  236 ALEKALPEIQAQQDKWTEKPAFGTPLEEHLKRSGREIALP--IEACVMMLLETGMKEEGLFRIAAGASKLKKLKAALDCSTSQLEEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWNHAGNIPDQNTKLQALWVVCQKLPKPNLENFRYLVKFLAKLSHHSDINKMTPSNIAIVLGPNLLWARHE 420

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BLAST of Rho GTPase-activating protein vs. Ensembl Mouse
Match: Arhgap8 (Rho GTPase activating protein 8 [Source:MGI Symbol;Acc:MGI:1920417])

HSP 1 Score: 245.358 bits (625), Expect = 1.133e-74
Identity = 138/375 (36.80%), Postives = 213/375 (56.80%), Query Frame = 3

Query:  318 DHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIW 1442
             H F D+A+  ++QVAGDDR G+++     CR+PP++ +N  R   Y   TL Q V NDY+++YFHYGL+ +N P + ++ N YK+ DR +KKNLK LY+VHPT+L+K + N   P  S K   K+     L+EL      DQ++IP                  P   ++D+           KL +   G       +         LP  QFGV+LQ+++  +    +PPV+   + YLR + L  EG+FRRSAS   + ++Q+ YD  + ++  +YGD HL A +LKTFLR L +PL+TF+ +++I+ + ++++ + V  CR ++   LP++NY VL+YL+ FL EV+  S  N M   N+A VF  +LIW
Sbjct:   11 SHPFYDVARHGILQVAGDDRQGRRIFTFSCCRLPPLHQLNHQRLLEYLKYTLDQHVENDYTIVYFHYGLSSQNKPSLGWLQNTYKEFDRKYKKNLKALYVVHPTSLIKALWNIFKPLISHKFGKKVTYCSNLRELREHLQCDQLLIP------------------PEVVRYDE-----------KLQNLHKGQPPPPTKT---PPPRPPLPTQQFGVSLQYLRDKNQGELIPPVLRWTVTYLREKGLRTEGLFRRSASAQTVRQVQRLYDQGKPVNFDDYGDMHLPAVILKTFLRELPQPLLTFQAYEQILGITSVESSLRVTHCR-LILRSLPEHNYAVLRYLMGFLHEVSLESISNKMNSSNLACVFGLNLIW 352

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Query:  318 DHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIW 1442
             H F D+A+  ++QVAGDDR G+++     CR+PP++ +N  R   Y   TL Q V NDY+++YFHYGL+ +N P + ++ N YK+ DR +KKNLK LY+VHPT+L+K + N   P  S K   K+     L+EL      DQ++IP                  P   ++D+           KL +   G       +         LP  QFGV+LQ+++  +    +PPV+   + YLR + L  EG+FRRSAS   + ++Q+ YD  + ++  +YGD HL A +LKTFLR L +PL+TF+ +++I+ + ++++ + V  CR ++   LP++NY VL+YL+ FL EV+  S  N M   N+A VF  +LIW
Sbjct:   11 SHPFYDVARHGILQVAGDDRQGRRIFTFSCCRLPPLHQLNHQRLLEYLKYTLDQHVENDYTIVYFHYGLSSQNKPSLGWLQNTYKEFDRKYKKNLKALYVVHPTSLIKALWNIFKPLISHKFGKKVTYCSNLRELREHLQCDQLLIP------------------PEVVRYDE-----------KLQNLHKGQPPPPTKT---PPPRPPLPTQQFGVSLQYLRDKNQGELIPPVLRWTVTYLREKGLRTEGLFRRSASAQTVRQVQRLYDQGKPVNFDDYGDMHLPAVILKTFLRELPQPLLTFQAYEQILGITSVESSLRVTHCR-LILRSLPEHNYAVLRYLMGFLHEVSLESISNKMNSSNLACVFGLNLIW 352

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Query:  318 DHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIW 1442
             H F D+A+  ++QVAGDDR G+++     CR+PP++ +N  R   Y   TL Q V NDY+++YFHYGL+ +N P + ++ N YK+ DR +KKNLK LY+VHPT+L+K + N   P  S K   K+     L+EL      DQ++IP                  P   ++D+           KL +   G       +         LP  QFGV+LQ+++  +    +PPV+   + YLR + L  EG+FRRSAS   + ++Q+ YD  + ++  +YGD HL A +LKTFLR L +PL+TF+ +++I+ + ++++ + V  CR ++   LP++NY VL+YL+ FL EV+  S  N M   N+A VF  +LIW
Sbjct:   11 SHPFYDVARHGILQVAGDDRQGRRIFTFSCCRLPPLHQLNHQRLLEYLKYTLDQHVENDYTIVYFHYGLSSQNKPSLGWLQNTYKEFDRKYKKNLKALYVVHPTSLIKALWNIFKPLISHKFGKKVTYCSNLRELREHLQCDQLLIP------------------PEVVRYDE-----------KLQNLHKGQPPPPTKT---PPPRPPLPTQQFGVSLQYLRDKNQGELIPPVLRWTVTYLREKGLRTEGLFRRSASAQTVRQVQRLYDQGKPVNFDDYGDMHLPAVILKTFLRELPQPLLTFQAYEQILGITSVESSLRVTHCR-LILRSLPEHNYAVLRYLMGFLHEVSLESISNKMNSSNLACVFGLNLIW 352

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BLAST of Rho GTPase-activating protein vs. Ensembl Mouse
Match: Arhgap1 (Rho GTPase activating protein 1 [Source:MGI Symbol;Acc:MGI:2445003])

HSP 1 Score: 244.202 bits (622), Expect = 3.786e-74
Identity = 138/378 (36.51%), Postives = 217/378 (57.41%), Query Frame = 3

Query:  318 DHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYH-SKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSR 1448
            D  + DIA+  +V+VAGDD++G+K+I+  ACR+PP + ++  +   Y   TL Q+V +DY+L+Y H+GLT  N P + ++ +AY++ DR +KKN+K LYIVHPT  +K ++    P  S K   KI  V  L EL     L+Q+ IP  +                   K+DDF    +K       SP++                  LP  QFGV+LQH+++    +  +P V+ + + YL++  L  EGIFRRSA+   + E+Q+KY++   +D  +Y + HL A +LKTFLR L EPL+TF+L+  ++   N+     V++ +Q V   LP+ NY VL +L  FL++++ H D+N MT  N+A VF P+L+W++
Sbjct:   61 DDPYYDIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKHTLDQYVESDYTLLYLHHGLTSDNKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPLISFKFGRKIFYVNYLSELSEHVKLEQLGIPRQV------------------LKYDDFLKSTQK-------SPATAPKPMPPRP--------PLPNQQFGVSLQHLQEKSPGQDPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVEVTQQ-VLQTLPEENYQVLHFLTAFLVQISAHCDQNKMTNTNLAVVFGPNLLWAK 404

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Query:  318 DHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYH-SKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSR 1448
            D  + DIA+  +V+VAGDD++G+K+I+  ACR+PP + ++  +   Y   TL Q+V +DY+L+Y H+GLT  N P + ++ +AY++ DR +KKN+K LYIVHPT  +K ++    P  S K   KI  V  L EL     L+Q+ IP  +                   K+DDF    +K       SP++                  LP  QFGV+LQH+++    +  +P V+ + + YL++  L  EGIFRRSA+   + E+Q+KY++   +D  +Y + HL A +LKTFLR L EPL+TF+L+  ++   N+     V++ +Q V   LP+ NY VL +L  FL++++ H D+N MT  N+A VF P+L+W++
Sbjct:   61 DDPYYDIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKHTLDQYVESDYTLLYLHHGLTSDNKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPLISFKFGRKIFYVNYLSELSEHVKLEQLGIPRQV------------------LKYDDFLKSTQK-------SPATAPKPMPPRP--------PLPNQQFGVSLQHLQEKSPGQDPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVEVTQQ-VLQTLPEENYQVLHFLTAFLVQISAHCDQNKMTNTNLAVVFGPNLLWAK 404

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BLAST of Rho GTPase-activating protein vs. UniProt/SwissProt
Match: sp|Q9CXP4|RHG08_MOUSE (Rho GTPase-activating protein 8 OS=Mus musculus OX=10090 GN=Arhgap8 PE=2 SV=3)

HSP 1 Score: 245.358 bits (625), Expect = 7.928e-74
Identity = 138/375 (36.80%), Postives = 213/375 (56.80%), Query Frame = 3

Query:  318 DHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIW 1442
             H F D+A+  ++QVAGDDR G+++     CR+PP++ +N  R   Y   TL Q V NDY+++YFHYGL+ +N P + ++ N YK+ DR +KKNLK LY+VHPT+L+K + N   P  S K   K+     L+EL      DQ++IP                  P   ++D+           KL +   G       +         LP  QFGV+LQ+++  +    +PPV+   + YLR + L  EG+FRRSAS   + ++Q+ YD  + ++  +YGD HL A +LKTFLR L +PL+TF+ +++I+ + ++++ + V  CR ++   LP++NY VL+YL+ FL EV+  S  N M   N+A VF  +LIW
Sbjct:   11 SHPFYDVARHGILQVAGDDRQGRRIFTFSCCRLPPLHQLNHQRLLEYLKYTLDQHVENDYTIVYFHYGLSSQNKPSLGWLQNTYKEFDRKYKKNLKALYVVHPTSLIKALWNIFKPLISHKFGKKVTYCSNLRELREHLQCDQLLIP------------------PEVVRYDE-----------KLQNLHKGQPPPPTKT---PPPRPPLPTQQFGVSLQYLRDKNQGELIPPVLRWTVTYLREKGLRTEGLFRRSASAQTVRQVQRLYDQGKPVNFDDYGDMHLPAVILKTFLRELPQPLLTFQAYEQILGITSVESSLRVTHCR-LILRSLPEHNYAVLRYLMGFLHEVSLESISNKMNSSNLACVFGLNLIW 352

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BLAST of Rho GTPase-activating protein vs. UniProt/SwissProt
Match: sp|Q07960|RHG01_HUMAN (Rho GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=ARHGAP1 PE=1 SV=1)

HSP 1 Score: 245.358 bits (625), Expect = 9.118e-74
Identity = 139/378 (36.77%), Postives = 216/378 (57.14%), Query Frame = 3

Query:  318 DHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCH-VPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSR 1448
            D  + DIA+  +V+VAGDD++G+K+I+  ACR+PP + ++  +   Y   TL Q+V +DY+L+Y H+GLT  N P + ++ +AY++ DR +KKN+K LYIVHPT  +K ++    P  S K   KI  V  L EL     L+Q+ IP                      K+DDF    +K       SP++                  LP  QFGV+LQH+++ + +   +P V+ + + YL++  L  EGIFRRSA+   + E+Q+KY++   +D  +Y + HL A +LKTFLR L EPL+TF+L+  ++   N+     V    Q V   LP+ NY VL++L  FL++++ HSD+N MT  N+A VF P+L+W++
Sbjct:   61 DDPYYDIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKHTLDQYVESDYTLLYLHHGLTSDNKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPLISFKFGQKIFYVNYLSELSEHVKLEQLGIPR------------------QVLKYDDFLKSTQK-------SPATAPKPMPPRP--------PLPNQQFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQ-VLQTLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWAK 404

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BLAST of Rho GTPase-activating protein vs. UniProt/SwissProt
Match: sp|Q5FWK3|RHG01_MOUSE (Rho GTPase-activating protein 1 OS=Mus musculus OX=10090 GN=Arhgap1 PE=1 SV=1)

HSP 1 Score: 244.202 bits (622), Expect = 2.648e-73
Identity = 138/378 (36.51%), Postives = 217/378 (57.41%), Query Frame = 3

Query:  318 DHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYH-SKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSR 1448
            D  + DIA+  +V+VAGDD++G+K+I+  ACR+PP + ++  +   Y   TL Q+V +DY+L+Y H+GLT  N P + ++ +AY++ DR +KKN+K LYIVHPT  +K ++    P  S K   KI  V  L EL     L+Q+ IP  +                   K+DDF    +K       SP++                  LP  QFGV+LQH+++    +  +P V+ + + YL++  L  EGIFRRSA+   + E+Q+KY++   +D  +Y + HL A +LKTFLR L EPL+TF+L+  ++   N+     V++ +Q V   LP+ NY VL +L  FL++++ H D+N MT  N+A VF P+L+W++
Sbjct:   61 DDPYYDIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKHTLDQYVESDYTLLYLHHGLTSDNKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPLISFKFGRKIFYVNYLSELSEHVKLEQLGIPRQV------------------LKYDDFLKSTQK-------SPATAPKPMPPRP--------PLPNQQFGVSLQHLQEKSPGQDPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVEVTQQ-VLQTLPEENYQVLHFLTAFLVQISAHCDQNKMTNTNLAVVFGPNLLWAK 404

[Close]

BLAST of Rho GTPase-activating protein vs. UniProt/SwissProt
Match: sp|P85298|RHG08_HUMAN (Rho GTPase-activating protein 8 OS=Homo sapiens OX=9606 GN=ARHGAP8 PE=1 SV=1)

HSP 1 Score: 233.802 bits (595), Expect = 4.222e-69
Identity = 144/406 (35.47%), Postives = 214/406 (52.71%), Query Frame = 3

Query:  318 DHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRD-------------------------------FKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIW 1442
             H F D+A+  ++QVAGDDRFG++V+    CR+PP + ++  R   Y   TL Q+V NDY+++YFHYGL  +N P + ++ +AYK+ DR                                +KKNLK LY+VHPT+ +K + N L P  S K   K+I    L EL      DQ+VIP                  P   ++D+           KL S   G       +         LP  QFGV+LQ++K  +    +PPV+   + YLR + L  EG+FRRSAS   + EIQ+ Y+  + ++  +YGD H+ A +LKTFLR L +PL+TF+ +++I+ +  +++ + V  CRQI+   LP++NY VL+YL+ FL  V+  S  N M   N+A VF  +LIW
Sbjct:   11 SHPFYDVARHGILQVAGDDRFGRRVVTFSCCRMPPSHELDHQRLLEYLKYTLDQYVENDYTIVYFHYGLNSRNKPSLGWLQSAYKEFDRKDGDLTMWPRLVSNSKLKRSSHLSLPKYWDYRYKKNLKALYVVHPTSFIKVLWNILKPLISHKFGKKVIYFNYLSELHEHLKYDQLVIP------------------PEVLRYDE-----------KLQSLHEGRTPPPTKT---PPPRPPLPTQQFGVSLQYLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILRS-LPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIW 383

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BLAST of Rho GTPase-activating protein vs. UniProt/SwissProt
Match: sp|Q9VTU3|RG68F_DROME (Rho GTPase-activating protein 68F OS=Drosophila melanogaster OX=7227 GN=RhoGAP68F PE=1 SV=1)

HSP 1 Score: 198.364 bits (503), Expect = 1.298e-55
Identity = 125/364 (34.34%), Postives = 200/364 (54.95%), Query Frame = 3

Query:  366 GDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKC--HVPPVMEQCIMYLR-SECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSR 1448
            G D+ G+ +  IYA R P      L+ F    +K ++ FV NDY L+YFH GL + N P  +F+ N+YK++DR+F+KNLK LY+VHPT  ++ I N   PF S K + K++ +  L EL     L+++ +P+ I   D   + +  S++P T                    PSS  N   Q        +K     QFGV L+ I   +S C   +PP++ +C+  L  +  ++ EGIFRRS +  +++ ++++ +  E +DL    + H+ A LLK+FLR L EPL+TFEL++++    +   +       Q++ + LP+ NY + KY++EFL+ V +  D N MT  N+A VF P+ +WSR
Sbjct:  105 GTDKQGRHIFGIYASRFP--EKSQLEGFVREIIKEIEPFVENDYILVYFHQGLKEDNKPSAQFLWNSYKELDRNFRKNLKTLYVVHPTWFIRVIWNFFSPFISDKFRKKLVYISSLDELRQALGLNKLKLPDNICDLD---DKLNPSRKPST------------------PPPSSNINASRQQQ------HKMATTHQFGVPLKFI-VMNSPCLNSIPPIVRKCVDSLSITGVIDTEGIFRRSGNHSEIMALKERVNRGEDVDLKSV-NVHVIAGLLKSFLRDLAEPLLTFELYEDVTGFLDWPKEERSRNVTQLIREKLPEENYELFKYIVEFLVRVMDCEDLNKMTSSNLAIVFGPNFLWSR 437

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BLAST of Rho GTPase-activating protein vs. TrEMBL
Match: A0A267EB39 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig029893g3 PE=4 SV=1)

HSP 1 Score: 322.398 bits (825), Expect = 4.420e-100
Identity = 183/458 (39.96%), Postives = 254/458 (55.46%), Query Frame = 3

Query:  165 FVGTQLTCKMAEENESEFSVGPDTSTLELF-DANFEKELGSSNKIFTSQDMIDHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAX-XXXXXXXXXXXXXXXXQFYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSRHEXXXXXXXXXXXXXXXXXXNYEEIFAR 1532
            F  T  T   ++EN +  +      T E F D +FE  LGS      +QD++D EF DI+KL V+QV GDDR G+KVII  ACR+PP NT++  R   Y + TL Q+V NDY L+YFH+GL  KN P   ++  AY + DR +KKNLK   IVHPT L+K +     P  S K  +         +      +LDQM IP+ ++  D    S  ++   H    ++                       S            LP +QFGV+LQHIK Y++   + PV+E  + YLR  CL+ EGIFRRS S   + E+Q+KY+  E ++  +  DPHLAA LLKTFLR L EPL+TFEL+D +I+ H+L     V    ++V + LPD NY +L Y++ FL EVAE++ KN MT  N+  VF P+LIWSR + S +++     F  LL+ +Y +IF R
Sbjct:   57 FSKTGTTDDQSDENFAAAAAAGGRITPEGFIDEDFEDTLGSPATEVNTQDLVDTEFKDISKLGVIQVVGDDRLGRKVIIFSACRLPPSNTLDHQRLLKYIINTLNQYVENDYVLVYFHHGLNSKNKPSFAWLKQAYSEFDRKYKKNLKAFLIVHPTKLIKALYYLFRPLLSVKFGRKLAYVNYLSELKSHNLFLDQMPIPQRVREYDDSLRSGSRTGSSHYASSEEL-------------------GCASGGLGVGGLAANPLPTTQFGVSLQHIKHYNAGSVICPVVEHTVTYLRDCCLDVEGIFRRSCSVTLVREVQEKYNKGESVEFRDLADPHLAAVLLKTFLRELAEPLLTFELYDAVIENHSLPAKQKVGHAAELVSNQLPDDNYDLLNYIVHFLSEVAENASKNKMTAVNLGIVFGPNLIWSRQQASLTVMKPINCFAQLLISDYAQIFLR 495

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BLAST of Rho GTPase-activating protein vs. TrEMBL
Match: A0A267FHB0 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig002115g2 PE=4 SV=1)

HSP 1 Score: 321.627 bits (823), Expect = 7.835e-100
Identity = 175/428 (40.89%), Postives = 242/428 (56.54%), Query Frame = 3

Query:  252 FDANFEKELGSSNKIFTSQDMIDHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAX-XXXXXXXXXXXXXXXXQFYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSRHEXXXXXXXXXXXXXXXXXXNYEEIFAR 1532
             D +FE  LGS      +QD++D EF DI+KL V+QV GDDR G+KVII  ACR+PP NT++  R   Y + TL Q+V NDY L+YFH+GL  KN P   ++  AY + DR +KKNLK   IVHPT L+K +     P  S K  +         +      +LDQM IP+ ++  D    S  ++   H    ++                       S            LP +QFGV+LQHIK Y++   + PV+E  + YLR  CL+ EGIFRRS S   + E+Q+KY+  E ++  +  DPHLAA LLKTFLR L EPL+TFEL+D +I+ H+L     V    ++V + LPD NY +L Y++ FL EVAE++ KN MT  N+  VF P+LIWSR + S +++     F  LL+ +Y +IF R
Sbjct:   93 IDEDFEDTLGSPATEVNTQDLVDTEFKDISKLGVIQVVGDDRLGRKVIIFSACRLPPSNTLDHQRLLKYIINTLNQYVENDYVLVYFHHGLNSKNKPSFAWLKQAYSEFDRKYKKNLKAFLIVHPTKLIKALYYLFRPLLSVKFGRKLAYVNYLSELKSHNLFLDQMPIPQRVREYDDSLRSGSRTGSSHYASSEEL-------------------GCASGGLGVGGLAANPLPTTQFGVSLQHIKHYNAGSVICPVVEHTVTYLRDCCLDVEGIFRRSCSVTLVREVQEKYNKGESVEFRDLADPHLAAVLLKTFLRELAEPLLTFELYDAVIENHSLPAKQKVGHAAELVSNQLPDDNYDLLNYIVHFLSEVAENASKNKMTAVNLGIVFGPNLIWSRQQASLTVMKPINCFAQLLISDYAQIFLR 501

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BLAST of Rho GTPase-activating protein vs. TrEMBL
Match: A0A267FCW5 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig015581g2 PE=4 SV=1)

HSP 1 Score: 321.242 bits (822), Expect = 1.930e-99
Identity = 192/468 (41.03%), Postives = 271/468 (57.91%), Query Frame = 3

Query:  141 TFDDYEDDFVGTQL--TCKMAEENESEFSVGPDTSTLELF-DANFEKELGSSNKIFTSQDMIDHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQ-FYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSRHEXXXXXXXXXXXXXXXXXXNYEEIFAR 1532
            TF+DY+   V  QL       E++ S+ ++G    T E + D +FE  LGS      +QD++D EF +I++L ++QV GDDR G+KVII  ACR+PP   ++  R   Y + TL Q+V NDY L+YFH+GL  KN P   ++  AY + DR +KKNLK   IVHPT L+K +     PF S K   K+  V  L +L+SQ  Y DQ+ IP+ ++  D        ++   T ++                   S D  Y Q    N      LP +QFGV+LQHIK Y+    + PV+E  I YLR  CL+ EG+FRRS S  ++ ++Q+KY+  E++D  + G+PHLAA LLKTFLR L EPL+TFEL++ +I+ H L     V   R ++   LPD NY +L Y+ +FL EVA++S +N MT  N+  VF PSLIWSR + S +++     FT LL+L+Y  IF R
Sbjct:   76 TFEDYDAIPVEDQLYFMANNPEDDPSDENLGAGRITPEGYIDEDFEDTLGSPATEVNTQDLVDTEFKEISRLGIIQVVGDDRLGRKVIIFSACRLPPAENLDHQRLLKYIINTLSQYVENDYVLVYFHHGLNSKNKPSFAWLKQAYSEFDRKYKKNLKAFLIVHPTKLIKALYFLFKPFISVKFGRKLTYVNYLADLKSQNLYFDQLPIPQRVREYDDSIQPASGNRAALTSQYS-----------------RSEDFAYGQQLVAN-----PLPTTQFGVSLQHIKHYNGGSVICPVVEHTIKYLRECCLDVEGLFRRSCSVAQVQDVQEKYNRGEYVDFRDLGNPHLAAVLLKTFLRELAEPLLTFELYEAVIENHALPAKTKVSHARSLISQQLPDDNYDLLNYVAQFLSEVADNSTRNKMTALNLGIVFGPSLIWSRQQASLTVMKPINCFTQLLILHYNHIFVR 521

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BLAST of Rho GTPase-activating protein vs. TrEMBL
Match: A0A1I8HPU5 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 319.316 bits (817), Expect = 5.365e-99
Identity = 188/465 (40.43%), Postives = 266/465 (57.20%), Query Frame = 3

Query:  141 TFDDYEDDFVGTQLTCKMAEENESEFSVGPDTSTLELFDANFEKELGSSNKIFTSQDMIDHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQ-FYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSRHEXXXXXXXXXXXXXXXXXXNYEEIFAR 1532
            TF+DY++D          ++EN     + P+       D +FE  LGS      +QD++D EF +I++L ++QV GDDR G+KVII  ACR+PP   ++  R   Y + TL Q+V NDY L+YFH+GL  KN P   ++  AY + DR +KKNLK   IVHPT L+K +     PF S K   K+  V  L +L+SQ  Y DQ+ IP+ ++  D        ++   T ++                   S D  Y Q    N      LP +QFGV+LQHIK Y+    + PV+E  I YLR  CL+ EG+FRRS S  ++ ++Q+KY+  E++D  + G+PHLAA LLKTFLR L EPL+TFEL++ +I+ H L     V   R ++   LPD NY +L Y+ +FL EVA++S +N MT  N+  VF PSLIWSR + S +++     FT LL+L+Y  IF R
Sbjct:   61 TFEDYDED--------DPSDENLGAGRITPEG----YIDEDFEDTLGSPATEVNTQDLVDTEFKEISRLGIIQVVGDDRLGRKVIIFSACRLPPAENLDHQRLLKYIINTLSQYVENDYVLVYFHHGLNSKNKPSFAWLKQAYSEFDRKYKKNLKAFLIVHPTKLIKALYFLFKPFISVKFGRKLTYVNYLADLKSQNLYFDQLPIPQRVREYDDSIQPASGNRAALTSQYS-----------------RSEDFAYGQQLVAN-----PLPTTQFGVSLQHIKHYNGGSVICPVVEHTIKYLRECCLDVEGLFRRSCSVAQVQDVQEKYNRGEYVDFRDLGNPHLAAVLLKTFLRELAEPLLTFELYEAVIENHALPAKTKVSHARSLISQQLPDDNYDLLNYVAQFLSEVADNSTRNKMTALNLGIVFGPSLIWSRQQASLTVMKPINCFTQLLILHYNHIFVR 491

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BLAST of Rho GTPase-activating protein vs. TrEMBL
Match: A0A267DWH9 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig005901g2 PE=4 SV=1)

HSP 1 Score: 317.775 bits (813), Expect = 2.834e-98
Identity = 185/447 (41.39%), Postives = 262/447 (58.61%), Query Frame = 3

Query:  198 EENESEFSVGPDTSTLELF-DANFEKELGSSNKIFTSQDMIDHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQ-FYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSRHEXXXXXXXXXXXXXXXXXXNYEEIFAR 1532
            E++ S+ ++G    T E + D +FE  LGS      +QD++D EF +I++L ++QV GDDR G+KVII  ACR+PP   ++  R   Y + TL Q+V NDY L+YFH+GL  KN P   ++  AY + DR +KKNLK   IVHPT L+K +     PF S K   K+  V  L +L+SQ  Y DQ+ IP+ ++  D        ++   T ++                   S D  Y Q    N      LP +QFGV+LQHIK Y+    + PV+E  I YLR  CL+ EG+FRRS S  ++ ++Q+KY+  E++D  + G+PHLAA LLKTFLR L EPL+TFEL++ +I+ H L     V   R ++   LPD NY +L Y+ +FL EVA++S +N MT  N+  VF PSLIWSR + S +++     FT LL+L+Y  IF R
Sbjct:   73 EDDPSDENLGAGRITPEGYIDEDFEDTLGSPATEVNTQDLVDTEFKEISRLGIIQVVGDDRLGRKVIIFSACRLPPAENLDHQRLLKYIINTLSQYVENDYVLVYFHHGLNSKNKPSFAWLKQAYSEFDRKYKKNLKAFLIVHPTKLIKALYFLFKPFISVKFGRKLTYVNYLADLKSQNLYFDQLPIPQRVREYDDSIQPASGNRAALTSQYS-----------------RSEDFAYGQQLVAN-----PLPATQFGVSLQHIKHYNGGSVICPVVEHTIKYLRECCLDVEGLFRRSCSVAQVQDVQEKYNRGEYVDFRDLGNPHLAAVLLKTFLRELAEPLLTFELYEAVIENHALPAKTKVSHARSLISQQLPDDNYDLLNYVAQFLSEVADNSTRNKMTALNLGIVFGPSLIWSRQQASLTVMKPINCFTQLLILHYNHIFVR 497

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BLAST of Rho GTPase-activating protein vs. Ensembl Cavefish
Match: ARHGAP8 (Rho GTPase activating protein 8 [Source:NCBI gene;Acc:103027805])

HSP 1 Score: 234.958 bits (598), Expect = 6.824e-71
Identity = 134/375 (35.73%), Postives = 212/375 (56.53%), Query Frame = 3

Query:  318 DHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIW 1442
             H + D+A+  ++QV GDD++G+K+II  +C +PP + +N  R   Y   TL Q+V +DY+++YFHYGL   N P ++++ +AY++ DR +KKNLK LY+VHPTN +K I N   P  S K   K+  V  L EL      DQ++IP  +                               HD +L +   G         P           QFGV+LQ+I++ ++   +PPVM Q + YL+ + L+ EGIFRRSA    + +IQK Y+  + +   +Y D H+ A +LKTFLR L EP++TF ++++I +L  +++ + V  C++I+ + LP++N+ V+KYL+ FL  V++ S  N M+  N+A VF  +L W
Sbjct:   42 SHPYYDVARHGILQVTGDDKYGRKLIIFSSCCMPPSHQLNHHRLLEYLKYTLDQYVESDYTVVYFHYGLRSINKPSLRWLRDAYREFDRKYKKNLKTLYVVHPTNFIKVIWNIFKPVISHKFGKKLTYVNYLAELREHLNYDQLIIPPAVLR-----------------------------HDEELRAAQKGGPPPPAKVPPPRPPLPT---QQFGVSLQYIREKNNNTLIPPVMFQTVSYLKLKGLKTEGIFRRSARVQLIKDIQKLYNQGKPVIFDQYSDVHVPAVILKTFLRELPEPVLTFTVYNQIQELTKVESSLRVSRCKRIM-ESLPEHNFIVVKYLVCFLHMVSQESISNKMSSSNLACVFGVNLAW 383

[Close]

BLAST of Rho GTPase-activating protein vs. Ensembl Cavefish
Match: arhgap1 (Rho GTPase activating protein 1 [Source:NCBI gene;Acc:103040311])

HSP 1 Score: 225.713 bits (574), Expect = 2.535e-67
Identity = 139/378 (36.77%), Postives = 215/378 (56.88%), Query Frame = 3

Query:  318 DHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKC-HVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSR 1448
            D  F DIAK  +V+VAGDD FG+KVI+  ACR+PP + ++  +   Y  +TL ++V +DY+LIYFH+G+T +N   + ++ +AY++ +R +KKN+K  YIVHPT  ++ ++    P  S K   KI  V  L ELE     DQ+VIP  ++                   +DD   +N K        PS    +   +S P +     LP  QFGV L  ++   +    +P V+   I +L+ + L+ EGIFRRSA+   +  IQ KY+  E ++  +  D HLAA +LKTFLR L EPL+TF L+++++   N+ ++  V +  Q +   LP+ NY  L++LI+FL +V+  S+ N MT  N+A VF P+L+W +
Sbjct:   61 DDPFYDIAKHQIVEVAGDDNFGRKVIVFSACRMPPHSQLDHHKLLMYLKQTLDKYVESDYTLIYFHHGMTSENKLSLSWLRDAYREFERKYKKNIKAFYIVHPTIFIRTVLIFFKPLISFKFGRKIHYVNYLSELEEIVKCDQLVIPSRVRA------------------YDDKIRLNLK--------PSV---VPGPISPPRSP---PLPFQQFGVPLSVLRDRGADADGIPLVIRDTISFLQEQGLQTEGIFRRSANVSLVKNIQLKYNSGEEVNFFQIEDVHLAAVILKTFLRELPEPLLTFRLYNDVVNFQNVDSESQV-VTIQNMLRSLPEENYATLRFLIQFLAQVSAESEANKMTNTNLAVVFGPNLLWGQ 405

[Close]

BLAST of Rho GTPase-activating protein vs. Ensembl Cavefish
Match: arhgap1 (Rho GTPase activating protein 1 [Source:NCBI gene;Acc:103040311])

HSP 1 Score: 208.764 bits (530), Expect = 8.537e-61
Identity = 138/385 (35.84%), Postives = 210/385 (54.55%), Query Frame = 3

Query:  318 DHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCHVPPVMEQCIMYLRS--------ECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSR 1448
            D  F DIAK  +V+VAGDD FG+KVI+  ACR+PP + ++  +   Y  +TL ++V +DY+LIYFH+G+T +N   + ++ +AY++ +R +KKN+K  YIVHPT  ++ ++    P  S K   KI  V  L ELE     DQ+VIP  ++                   +DD   +N K        PS    +   +S P +     LP  QFGV L  I         P  +   + ++ S          L+ EGIFRRSA+   +  IQ KY+  E ++  +  D HLAA +LKTFLR L EPL+TF L+++++   N ++D +  +  Q +   LP+ NY  L++LI+FL +V+  S+ N MT  N+A VF P+L+W +
Sbjct:   59 DDPFYDIAKHQIVEVAGDDNFGRKVIVFSACRMPPHSQLDHHKLLMYLKQTLDKYVESDYTLIYFHHGMTSENKLSLSWLRDAYREFERKYKKNIKAFYIVHPTIFIRTVLIFFKPLISFKFGRKIHYVNYLSELEEIVKCDQLVIPSRVRA------------------YDDKIRLNLK--------PSV---VPGPISPPRS---PPLPFQQFGVPLSVIVLCSDAVLFPHDISIYLFFVFSCSQFSLLHSGLQTEGIFRRSANVSLVKNIQLKYNSGEEVNFFQIEDVHLAAVILKTFLRELPEPLLTFRLYNDVV---NFQSDESQVVTIQNMLRSLPEENYATLRFLIQFLAQVSAESEANKMTNTNLAVVFGPNLLWGQ 408

[Close]

BLAST of Rho GTPase-activating protein vs. Ensembl Cavefish
Match: arhgap1 (Rho GTPase activating protein 1 [Source:NCBI gene;Acc:103040311])

HSP 1 Score: 202.216 bits (513), Expect = 8.749e-59
Identity = 124/378 (32.80%), Postives = 200/378 (52.91%), Query Frame = 3

Query:  318 DHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKC-HVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSR 1448
            D  F DIAK  +V+VAGDD FG+KVI+  ACR+PP + ++  +   Y  +TL ++V +DY+LIYFH+G+T +N   + ++ +AY++ +R+FK   K  Y+ + + L + +                               DQ+VIP  ++                   +DD   +N K        PS    +   +S P +     LP  QFGV L  ++   +    +P V+   I +L+ + L+ EGIFRRSA+   +  IQ KY+  E ++  +  D HLAA +LKTFLR L EPL+TF L+++++   N+ ++  V +  Q +   LP+ NY  L++LI+FL +V+  S+ N MT  N+A VF P+L+W +
Sbjct:   61 DDPFYDIAKHQIVEVAGDDNFGRKVIVFSACRMPPHSQLDHHKLLMYLKQTLDKYVESDYTLIYFHHGMTSENKLSLSWLRDAYREFERNFKFGRKIHYVNYLSELEEIV-----------------------------KCDQLVIPSRVRA------------------YDDKIRLNLK--------PSV---VPGPISPPRS---PPLPFQQFGVPLSVLRDRGADADGIPLVIRDTISFLQEQGLQTEGIFRRSANVSLVKNIQLKYNSGEEVNFFQIEDVHLAAVILKTFLRELPEPLLTFRLYNDVVNFQNVDSESQV-VTIQNMLRSLPEENYATLRFLIQFLAQVSAESEANKMTNTNLAVVFGPNLLWGQ 376

[Close]

BLAST of Rho GTPase-activating protein vs. Ensembl Cavefish
Match: ARHGAP17 (Rho GTPase activating protein 17 [Source:NCBI gene;Acc:103031684])

HSP 1 Score: 115.546 bits (288), Expect = 1.405e-26
Identity = 62/166 (37.35%), Postives = 97/166 (58.43%), Query Frame = 3

Query:  960 FGVTLQ-HIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSRHE 1454
            FG  L+ H+K+ + +  +P  +E C+M L    ++ EG+FR +A   KL +++   D +       Y DPH  A  LK++LR L EPLMTF+L+DE I+  N+           ++CD LP  N   L+YL++FL ++A+ S+ N MT  NIA V  P+L+W++ E
Sbjct:  253 FGTALEEHLKRTNREIALP--IEACVMMLLETGMKEEGLFRIAAGASKLKKLKAALDCSTSQLEEFYSDPHAVAGALKSYLRELPEPLMTFQLYDEWIQASNISDSDKRLQALWVICDSLPKANKANLRYLVKFLAKLAQESEVNKMTPSNIAIVLGPNLLWAKTE 416

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BLAST of Rho GTPase-activating protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002340.1 (pep scaffold:Pmarinus_7.0:GL481985:13400:22843:-1 gene:ENSPMAG00000002118.1 transcript:ENSPMAT00000002340.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 242.276 bits (617), Expect = 9.659e-75
Identity = 144/378 (38.10%), Postives = 213/378 (56.35%), Query Frame = 3

Query:  321 HEFSDIAKLNVVQV--AGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSR 1448
            H + D+A+  +V+V   G+D  G+KVII   CR+PP + +N  +   Y   TL Q+V +DY+LIYFHYGLT +N P  +++LNAY++ DR +KKNLK LY+VHPTN ++ + + L PF S K   K++    L EL  Q     ++IP                  P   +FD+     EK+   K+ +P++     + V  P T         QFGV L+ + + +S   +P V+   + YL+   L+ EGIFRRSAS   L E Q++Y+  + +D    GD HLAA +LKTFLR L EPL+TF L   I+ +  L+ D       ++V   LP+ N  VL +L++FL  V+ HS  N M+ +N+A VF P+L+W R
Sbjct:   13 HPYYDVARHGIVEVVGTGEDNLGRKVIIFSCCRMPPTHQLNHHKLLEYLRYTLDQYVESDYTLIYFHYGLTSENKPSFQWLLNAYREFDRKYKKNLKALYVVHPTNFIRVLWSFLKPFISYKFGRKVMYFNYLSELHQQMKDPMLIIP------------------PEVVRFDE-----EKNKRSKVMAPTAAQASVA-VDVPAT--------QQFGVGLKRLAE-NSGQLIPLVVRDTVAYLKEHGLQTEGIFRRSASTQALRETQERYNRGQPVDFQALGDVHLAAVILKTFLRELPEPLLTFSLFPYIVSVQGLEKDARGAAVVEMV-KKLPEENRAVLHHLLDFLKLVSPHSGVNKMSGENLAIVFGPNLVWER 356

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BLAST of Rho GTPase-activating protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006125.1 (pep scaffold:Pmarinus_7.0:GL477389:161447:166370:-1 gene:ENSPMAG00000005526.1 transcript:ENSPMAT00000006125.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 110.153 bits (274), Expect = 5.416e-28
Identity = 57/158 (36.08%), Postives = 98/158 (62.03%), Query Frame = 3

Query:  981 IKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYG--DPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSR 1448
            +K+  +   +P VM + + YL+   L+ EG+F+RS +   + E+Q+KY+L + +   EY   D  +AA  LKTFLR L EPL+T +L+ +I+ LH ++T + +   ++++   +P  NY+VLK+L+ FL  V + S  N  + +N+  VF P+L+W R
Sbjct:    1 LKEKSNGEDLPLVMRETVAYLKENGLKTEGLFQRSVNVQLIKEVQQKYNLGKPVRFDEYNKEDVRVAAVTLKTFLRELPEPLLTLQLYHKILALHRVETSLRITRIKEML-QTIPALNYNVLKFLMCFLNTVLDESIHNKTSARNLGFVFGPNLVWPR 157

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BLAST of Rho GTPase-activating protein vs. Ensembl Sea Lamprey
Match: ralbp1 (ralA binding protein 1 [Source:ZFIN;Acc:ZDB-GENE-040426-2098])

HSP 1 Score: 90.1225 bits (222), Expect = 3.270e-19
Identity = 58/163 (35.58%), Postives = 88/163 (53.99%), Query Frame = 3

Query:  960 FGVTLQ---HIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKL--HNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPS 1433
            FG TL+   H    +    +P V  +CI Y+    L+CEGI+R S  K K+ E++  YD  E  +L +Y DPH  A +LK +LR L E L+T ELH +I +     L  D   + C++++ + LP +N H+L +L+  +  V  H   N M  Q I+ V  P+
Sbjct:  198 FGATLEEAVHRTALYDGVPLPAVCRECIDYIERNGLKCEGIYRVSGIKSKVDELKAIYDREESPNLEDY-DPHTVASVLKQYLRELPESLLTRELHPKIEEACSRPLVEDRLAE-CKRLLAE-LPKFNRHLLSWLMVHMDHVVLHESDNKMNVQGISIVLHPT 357

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BLAST of Rho GTPase-activating protein vs. Ensembl Sea Lamprey
Match: si:ch211-247j9.1 (si:ch211-247j9.1 [Source:ZFIN;Acc:ZDB-GENE-091204-212])

HSP 1 Score: 85.8853 bits (211), Expect = 5.705e-18
Identity = 45/143 (31.47%), Postives = 79/143 (55.24%), Query Frame = 3

Query: 1017 VMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQI--VCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLI 1439
            ++ QC+ ++R + L  EG+FR       + E+Q+ +D  E        D H  A L+K +LR L EP++ F L+ E +   +L      +  +++  + + LP  N+++LKY+  FL EV  H+  N M+ QN+A VF P+++
Sbjct:    1 LVTQCVNFIRCQGLAEEGLFRLPGQTNLVRELQEAFDCGERPIFDGDTDVHTVASLVKLYLRELPEPVVPFSLYSEFLSCASLLAKNQSEGVKELTQLVNSLPLANFNLLKYICSFLYEVQSHASINKMSIQNLATVFGPNIL 143

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BLAST of Rho GTPase-activating protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005293.1 (pep scaffold:Pmarinus_7.0:GL478264:159922:165142:-1 gene:ENSPMAG00000004822.1 transcript:ENSPMAT00000005293.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 76.2554 bits (186), Expect = 6.291e-16
Identity = 48/142 (33.80%), Postives = 75/142 (52.82%), Query Frame = 3

Query: 1017 VMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEH-IDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLI 1439
            V+E C  YL+   L+ EGIFR+  S  ++ E++ + +  E  +  +   D    A LLK  LR   EPL+  ELH  + +   L T         ++C ++P    H L++L+ FL  VAE ++ N MT  N+A VF P+L+
Sbjct:    2 VLEAC-RYLQDH-LDTEGIFRKPGSLSRMRELKARLERGEACLAGATVND---VAGLLKQHLREAAEPLVPRELHSSLRRAQQLATAEERTRATLLLCLLMPPATAHTLRFLMTFLHSVAERAEDNKMTATNLAVVFTPTLM 138

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BLAST of Rho GTPase-activating protein vs. Ensembl Yeast
Match: RGA1 (GTPase-activating protein for polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth; relocalizes from bud neck to cytoplasm upon DNA replication stress; RGA1 has a paralog, RGA2, that arose from the whole genome duplication [Source:SGD;Acc:S000005653])

HSP 1 Score: 68.9366 bits (167), Expect = 1.278e-12
Identity = 49/174 (28.16%), Postives = 86/174 (49.43%), Query Frame = 3

Query: 1005 HVPPVMEQCIMYLRS--ECLECEGIFRRSASKLKLLEIQKKYDL------NEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKL---------------------HNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLI 1439
             +P ++  CI ++ S  E +  EGI+R+S S+L + EI+K++         E  ++    D ++   +LK +LR L  P+ TF++++ +++L                      N  T M+     + + + LP  +Y VL+ L E + +V  +S  N MT  N+A VFAP LI
Sbjct:  803 EIPMILSVCIDFIESDEENMRSEGIYRKSGSQLVIEEIEKQFSAWKVQQNTETPNILTEQDLNVVTGVLKRYLRKLPNPIFTFQIYEPLMRLVKSKKMMENLPFVGGKLSLEAKNSDTYMSSKSALKNILEDLPREHYRVLRVLSEHIEKVTRYSHWNRMTLYNLALVFAPGLI 976

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BLAST of Rho GTPase-activating protein vs. Ensembl Yeast
Match: BAG7 (Rho GTPase activating protein (RhoGAP); stimulates the intrinsic GTPase activity of Rho1p, which plays a bud growth by regulating actin cytoskeleton organization and cell wall biosynthesis, resulting in the downregulation of Rho1p; structurally and functionally related to Sac7p; BAG7 has a paralog, SAC7, that arose from the whole genome duplication [Source:SGD;Acc:S000005660])

HSP 1 Score: 65.0846 bits (157), Expect = 1.057e-11
Identity = 54/187 (28.88%), Postives = 87/187 (46.52%), Query Frame = 3

Query:  924 NTSFYKALPESQFGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYG---------DPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCD------MLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLI 1439
              S  ++L  +Q  V +Q  K  +    +P V+ +   YL+   L+  GIFR + S  ++ E+Q  +         +YG         + H  A LLK +L SL EPL+   L+D I +   L+     +   QI+ D      +LP  N H++ YL   L   A +  KN+M+  N+A +  PSL+
Sbjct:   49 GVSLEESLKVAQEEVIIQ--KSTNEIGSIPVVIAKSGKYLKENALDTTGIFRIAGSNKRVRELQAVFS-----KPPDYGRKFEGWCDFNVHDIATLLKRYLNSLSEPLVPLALYD-IFRNPILENPKINEHKEQIIKDYEDIYMLLPQQNRHLILYLAALLNLFARNEKKNLMSASNLAAIVQPSLL 227

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BLAST of Rho GTPase-activating protein vs. Ensembl Yeast
Match: LRG1 (GTPase-activating protein (GAP); contains Rho1p-specific GAP activity, interacting with activated forms of Rho1p; functions along with Sac7p as a negative regulator of the Pkc1p-mediated cell wall integrity signaling pathway; negative regulator of cell wall 1,3-beta-glucan biosynthesis; required for efficient cell fusion; contains a RhoGAP domain and three Lin-11-Isl1-Mec-3 (LIM) domains [Source:SGD;Acc:S000002399])

HSP 1 Score: 65.0846 bits (157), Expect = 1.981e-11
Identity = 44/159 (27.67%), Postives = 83/159 (52.20%), Query Frame = 3

Query:  999 KCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLN--EHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFL-----IEVAEHSDKNMMTFQNIANVFAPSLIWSRHE 1454
            K  +P ++++ I  LR   +  EGIFR++ +  +L E+    D N  E  D S+     L+A LLK F+R L +P+++ +L++  IK   +  +        ++  +LP YN ++L+ L+ FL         E+   + M   N++ V  P++++ RH+
Sbjct:  751 KIRIPIIIDELISSLRQMDMSVEGIFRKNGNIRRLRELTANIDSNPTEAPDFSKENAIQLSA-LLKKFIRELPQPILSTDLYELWIKAAKIDLEDEKQRVILLIYSLLPTYNRNLLEALLSFLHWTSSFSYIENEMGSKMDIHNLSTVITPNILYLRHK 908

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BLAST of Rho GTPase-activating protein vs. Ensembl Yeast
Match: RGD1 (GTPase-activating protein (RhoGAP) for Rho3p and Rho4p; possibly involved in control of actin cytoskeleton organization [Source:SGD;Acc:S000000464])

HSP 1 Score: 56.9954 bits (136), Expect = 5.947e-9
Identity = 44/166 (26.51%), Postives = 79/166 (47.59%), Query Frame = 3

Query:  960 FGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLN-EHIDLSEYGDPH------LAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSL 1436
            FGV L+ + ++     VP ++ QCI  +    L+ EGI+R+SA+ L + +++++ D +  +I +     PH      L   LLKTF  SL + ++   L  EI     ++           +   LPD  Y  L+ L+  L  V  H  +N M  + +  ++ P++
Sbjct:  470 FGVPLESLIEFEQDM-VPAIVRQCIYVIDKFGLDQEGIYRKSANVLDVSKLKEEIDKDPANISMILPSKPHSDSDIYLVGSLLKTFFASLPDSVLPKALSSEIKVCLQIEDPTTRKNFMHGLIYNLPDAQYWTLRALVFHLKRVLAHEAQNRMNLRALCIIWGPTI 634

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BLAST of Rho GTPase-activating protein vs. Ensembl Yeast
Match: BEM3 (Rho GTPase activating protein (RhoGAP); involved in control of the cytoskeleton organization; targets the essential Rho-GTPase Cdc42p, which controls establishment and maintenance of cell polarity, including bud-site assembly [Source:SGD;Acc:S000006036])

HSP 1 Score: 56.9954 bits (136), Expect = 5.949e-9
Identity = 47/174 (27.01%), Postives = 84/174 (48.28%), Query Frame = 3

Query:  987 QYHSKCHVPPVMEQCIMYL-RSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGD----------PHL------AACLLKTFLRSLK------EPLMTFE-LHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSL 1436
            +Y +   +P V+ +C+ YL ++  ++ EGIFR S S   +  +Q+++D    +DL  Y +          P L       + LLK +LR L       E  ++F+ + DE    HN    +++     I   ++P  N  ++  L E L+ + E+S  N M  +N+  VF+P+L
Sbjct:  919 KYQNVYDLPSVVYRCLEYLYKNRGIQEEGIFRLSGSSTVIKTLQERFDKEYDVDLCRYNESIEAKDDEASPSLYIGVNTVSGLLKLYLRKLPHLLFGDEQFLSFKRVVDEN---HNNPVQISLGFKELIESGLVPHANLSLMYALFELLVRINENSKFNKMNLRNLCIVFSPTL 1089

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BLAST of Rho GTPase-activating protein vs. Ensembl Nematostella
Match: EDO47995 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKJ0])

HSP 1 Score: 99.3673 bits (246), Expect = 2.847e-22
Identity = 64/170 (37.65%), Postives = 101/170 (59.41%), Query Frame = 3

Query:  954 SQFGVTLQ-HIK-QYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYG-DPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSRHE 1454
            S FG  L+ H+K Q  S   +  V+E+C+ YL  E L+ +G+FR + S  K+ +++  +D    +DL+E+  D H    +LK +LR L EPLMTF L+D+ I+  +++   A       + D LP  N   L+YLI FL ++A++S+ N MT  NIA V AP++I+S  +
Sbjct:  251 SVFGCPLEEHLKVQRRS---IAFVLEECLTYLHEEALQEQGLFRMAGSSGKIRKLKAAFDAG-MVDLTEFDCDVHAITGVLKQYLRELPEPLMTFALYDDWIQAASIQDSGARLQAYWGLVDKLPKANKDNLRYLICFLGKLADYSEVNKMTASNIAIVIAPNIIYSEQD 416

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BLAST of Rho GTPase-activating protein vs. Ensembl Nematostella
Match: EDO42235 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S270])

HSP 1 Score: 92.4337 bits (228), Expect = 8.431e-20
Identity = 54/149 (36.24%), Postives = 79/149 (53.02%), Query Frame = 3

Query: 1002 CHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSE---YGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLI 1439
            C VP  +     +LR + +  EG+FR+S S      +Q++  L E I+L E      PH  A L+K F R L+EPL+T   HD  IK   ++ D         +C +LP  +   LKY ++FL E A HS+K+ M F N+A V  P+L+
Sbjct:   65 CSVPKFLVDSAKFLR-QHMNTEGLFRKSGS------VQRQKLLKERIELGEEISTAQPHDVAGLMKQFFRQLQEPLLTNTYHDSFIKTMRIEDDNTRTKAMLYICLLLPLAHLQALKYTMKFLAEFASHSEKSKMGFSNLAIVLTPNLM 206

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BLAST of Rho GTPase-activating protein vs. Ensembl Nematostella
Match: EDO46865 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNI7])

HSP 1 Score: 85.1149 bits (209), Expect = 2.258e-17
Identity = 53/186 (28.49%), Postives = 100/186 (53.76%), Query Frame = 3

Query:  909 QVSYPNTSFYKALPE-----SQFGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEH--IDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVC--DMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLI 1439
            +++  N +  K L E     + F ++++ I    +   +P V+E C+ +++   L+  GIFR S S   + ++++ ++        L+ + D +  A LL+ + R L++PL     + + I+     T+   D+ RQ+ C  + LPD    V+KYL +FL +V+EHS++N M   N+A VF P+L+
Sbjct:  407 RIAAENQTLVKTLGELVDTANSFQLSIKQI----TGREIPEVVESCVRFIKRFGLDHPGIFRLSGSSTDINDMKQLFECGRDPLAGLNHWKDINAVAGLLRVYFRELEDPLFPSSHYQQFIEASRFPTNE--DVIRQVTCVINELPDSVNRVMKYLFKFLKQVSEHSEQNKMDAHNLAVVFGPTLL 586

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BLAST of Rho GTPase-activating protein vs. Ensembl Nematostella
Match: EDO47842 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKY9])

HSP 1 Score: 84.3445 bits (207), Expect = 4.515e-17
Identity = 55/160 (34.38%), Postives = 84/160 (52.50%), Query Frame = 3

Query:  957 QFGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQI--VCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAP 1430
            QFGV L+ + +      +P V+ + + YL    L+ EGIFR S +   +  ++  +D +   DL E  D    A LLK FLR L EP +   L  + IK+H +  D   D   ++  + D LP  NY +LK+L  FL+EV+ + + N M+   +A VF P
Sbjct:  102 QFGVPLEEVTKSRDGSPIPWVLAKIVHYLSQCGLKHEGIFRVSGNHKVVESLKATFDRDGDADLEEC-DVMAVAGLLKLFLRELPEPPVPQALTTDFIKVHEVYGDDNPDCLDELRALLDKLPYLNYELLKFLCHFLVEVSMNEENNKMSTMALAIVFGP 260

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BLAST of Rho GTPase-activating protein vs. Ensembl Nematostella
Match: EDO49778 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFT9])

HSP 1 Score: 80.4925 bits (197), Expect = 3.982e-16
Identity = 55/163 (33.74%), Postives = 86/163 (52.76%), Query Frame = 3

Query:  960 FGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLN-EHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDL---CRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSL 1436
            FGV +  + Q   +    P++   I YL+  C+E  GIFR+S  K ++  ++   + N EH D  E   P+  A +LK + R L +P++T +L +  I +H  K  +  +L     Q    ++PD N   L+ L+ FL EVAE+S  N M  +N+   FAPSL
Sbjct:   18 FGVPMSVVLQRSGQPLPRPIL-CAINYLQRTCVESVGIFRKSGGKQRINNLKDMMEDNPEHTDF-EGMSPYDLADMLKQYFRDLPDPILTSKLAETFITIHTCKYYIPAELRVEAMQAAILLMPDENREALQTLLLFLNEVAENSAVNQMNEKNLGVCFAPSL 178

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BLAST of Rho GTPase-activating protein vs. Ensembl Medaka
Match: ENSORLT00000024110.2 (Rho GTPase activating protein 1 [Source:NCBI gene;Acc:101165860])

HSP 1 Score: 238.424 bits (607), Expect = 3.364e-72
Identity = 145/378 (38.36%), Postives = 219/378 (57.94%), Query Frame = 3

Query:  318 DHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCH-VPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSR 1448
            DH F DIA+ ++++VAGDD FG+KVI+  ACR+PP + ++  +   Y   TL Q+V +DY+LIYFH+GLT  N P + ++ +AYK+ DR +KKN+K LYIVHPT  +K ++    P  S K   KI  V  L ELE     +Q++IP+ ++                  ++DD    + K       SP     + +QV               FGV L  ++Q       VP VM+  I +L  + +E EGIFRRSA+   + E+Q KY+  E ++  +  D HLAA +LKTFLR L EPL+TF+L+++I+   +L +D  V++ + ++ + LP+ NY  L+YLI FL +V+ +S+ N MT  N+A VF P+L+W R
Sbjct:   59 DHPFYDIARHHIIEVAGDDNFGRKVIVFSACRMPPQHELDHHKLLMYLKATLDQYVESDYTLIYFHHGLTSLNKPSLGWLRDAYKEFDRKYKKNIKALYIVHPTLFIKTLLVLFKPIISLKFGRKINYVSYLSELEDVVKCEQLLIPQRVQ------------------EYDDKLRASAKPSSPPPMSPPRSPPLPNQV---------------FGVPLSQLRQRSPDGDPVPMVMKDTINFLSEQGVEIEGIFRRSANVTLVKEVQAKYNSGEPVNFRDMEDVHLAAVILKTFLRELPEPLLTFQLYNDIVNFGSLSSDCRVEVMKTML-ESLPEENYASLRYLITFLAQVSNNSEVNKMTTSNLAVVFGPNLLWGR 402

[Close]

BLAST of Rho GTPase-activating protein vs. Ensembl Medaka
Match: ARHGAP8 (Rho GTPase activating protein 8 [Source:NCBI gene;Acc:101163873])

HSP 1 Score: 199.904 bits (507), Expect = 7.637e-58
Identity = 130/387 (33.59%), Postives = 202/387 (52.20%), Query Frame = 3

Query:  291 KIFTSQDMIDHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSRH 1451
            K+  + D   + F D+A+  ++QV+GDD FG+K I+  +CR+PP + ++  R   +   TL Q+V  DY L+YFH GL   N P +K++  AY + DR +KKNLK LY+VHPTN ++ + N   P  S K   K+  V  L EL      +Q+ IP      D  R                        HD KL +  S     +  +         LP  QFGVTL     Y + C    ++   +  L    L  EGIFRRS     + ++QK Y+  + +D   Y + H+ A +LK+FLR L EPL+TF +++++ ++  +++ + V  C+Q+V + LP++N+ VLK+L+ FL  V +    N M+  N+A VF  +L+W RH
Sbjct:   20 KVPITADDPSNPFYDVARHGIIQVSGDDLFGRKQIVFSSCRLPPSHQLDHRRLLQFLKFTLDQYVEMDYILVYFHCGLRSSNKPSVKWLREAYGEFDRKYKKNLKALYVVHPTNFIRIVWNIFKPLISRKFGKKLKYVNYLDELREHLNYEQLFIPA-----DVLR------------------------HDEKLRAAQSDAPPPAART---PPPRPPLPTQQFGVTL----HYSAPCAWETLVR--LQRLLLAGLRTEGIFRRSVQVQIIKDVQKLYNQGKPVDFDVYQNVHVPAVILKSFLRELPEPLLTFRVYNQVQEILGVESSLRVSRCKQVV-EGLPEHNFTVLKFLLGFLHTVTQEIIFNKMSASNLACVFGVNLVWPRH 367

[Close]

BLAST of Rho GTPase-activating protein vs. Ensembl Medaka
Match: arhgap17a (Rho GTPase activating protein 17 [Source:NCBI gene;Acc:101165596])

HSP 1 Score: 112.464 bits (280), Expect = 1.702e-25
Identity = 62/166 (37.35%), Postives = 96/166 (57.83%), Query Frame = 3

Query:  960 FGVTL-QHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSRHE 1454
            FG  L +H+K+   +  +P  ME C+M L    ++ EG+FR +A   KL +++   D +       Y DPH  A  LK++LR L EPLMT +L+DE I+  ++           +VCD LP  N + L+YL++FL ++A+ S+ N MT  NIA V  P+L+W++ E
Sbjct:  264 FGTALDEHLKRSAREIALP--MEACVMMLLETGMKEEGLFRIAAGASKLKKLKAALDCSTSQLEEFYSDPHAVAGALKSYLRELPEPLMTHQLYDEWIQASSVSDPDKRLQALWVVCDKLPKNNRNNLRYLVKFLAKLAQDSEANKMTPSNIAIVLGPNLLWAKTE 427

[Close]

BLAST of Rho GTPase-activating protein vs. Ensembl Medaka
Match: arhgap17a (Rho GTPase activating protein 17 [Source:NCBI gene;Acc:101165596])

HSP 1 Score: 112.079 bits (279), Expect = 1.878e-25
Identity = 62/166 (37.35%), Postives = 96/166 (57.83%), Query Frame = 3

Query:  960 FGVTL-QHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSRHE 1454
            FG  L +H+K+   +  +P  ME C+M L    ++ EG+FR +A   KL +++   D +       Y DPH  A  LK++LR L EPLMT +L+DE I+  ++           +VCD LP  N + L+YL++FL ++A+ S+ N MT  NIA V  P+L+W++ E
Sbjct:  264 FGTALDEHLKRSAREIALP--MEACVMMLLETGMKEEGLFRIAAGASKLKKLKAALDCSTSQLEEFYSDPHAVAGALKSYLRELPEPLMTHQLYDEWIQASSVSDPDKRLQALWVVCDKLPKNNRNNLRYLVKFLAKLAQDSEANKMTPSNIAIVLGPNLLWAKTE 427

[Close]

BLAST of Rho GTPase-activating protein vs. Ensembl Medaka
Match: arhgap17a (Rho GTPase activating protein 17 [Source:NCBI gene;Acc:101165596])

HSP 1 Score: 112.079 bits (279), Expect = 1.924e-25
Identity = 62/166 (37.35%), Postives = 96/166 (57.83%), Query Frame = 3

Query:  960 FGVTL-QHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSRHE 1454
            FG  L +H+K+   +  +P  ME C+M L    ++ EG+FR +A   KL +++   D +       Y DPH  A  LK++LR L EPLMT +L+DE I+  ++           +VCD LP  N + L+YL++FL ++A+ S+ N MT  NIA V  P+L+W++ E
Sbjct:  264 FGTALDEHLKRSAREIALP--MEACVMMLLETGMKEEGLFRIAAGASKLKKLKAALDCSTSQLEEFYSDPHAVAGALKSYLRELPEPLMTHQLYDEWIQASSVSDPDKRLQALWVVCDKLPKNNRNNLRYLVKFLAKLAQDSEANKMTPSNIAIVLGPNLLWAKTE 427

[Close]

BLAST of Rho GTPase-activating protein vs. Planmine SMEST
Match: SMESG000060252.1 (SMESG000060252.1)

HSP 1 Score: 906.746 bits (2342), Expect = 0.000e+0
Identity = 476/477 (99.79%), Postives = 477/477 (100.00%), Query Frame = 3

Query:  120 MTDLEGSTFDDYEDDFVGTQLTCKMAEENESEFSVGPDTSTLELFDANFEKELGSSNKIFTSQDMIDHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSRHEXXXXXXXXXXXXXXXXXXNYEEIFARESMGFM 1550
            MTDLEGSTFDDYEDDFVGTQLTCKMAEENESEFSVGPDTSTLELFDANFEKELGSSNKIFTSQDMIDHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAKVKSKIIKVKKLKELESQFYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKF+DFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSRHETSFSLIHIFIFFTHLLLLNYEEIFARESMGFM
Sbjct:    1 MTDLEGSTFDDYEDDFVGTQLTCKMAEENESEFSVGPDTSTLELFDANFEKELGSSNKIFTSQDMIDHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAKVKSKIIKVKKLKELESQFYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFNDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSRHETSFSLIHIFIFFTHLLLLNYEEIFARESMGFM 477

[Close]

BLAST of Rho GTPase-activating protein vs. Planmine SMEST
Match: SMESG000060252.1 (SMESG000060252.1)

HSP 1 Score: 830.476 bits (2144), Expect = 0.000e+0
Identity = 448/477 (93.92%), Postives = 448/477 (93.92%), Query Frame = 3

Query:  120 MTDLEGSTFDDYEDDFVGTQLTCKMAEENESEFSVGPDTSTLELFDANFEKELGSSNKIFTSQDMIDHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSRHEXXXXXXXXXXXXXXXXXXNYEEIFARESMGFM 1550
            MTDLEGSTFDDYEDDFVGTQLTCKMAEENESEFSVGPDTSTLELFDANFEKELGSSNKIFTSQDMIDHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAKVKSKIIKVKKLKELESQFYLDQMVIPEIIKT                             HDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSRHETSFSLIHIFIFFTHLLLLNYEEIFARESMGFM
Sbjct:    1 MTDLEGSTFDDYEDDFVGTQLTCKMAEENESEFSVGPDTSTLELFDANFEKELGSSNKIFTSQDMIDHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAKVKSKIIKVKKLKELESQFYLDQMVIPEIIKT-----------------------------HDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSRHETSFSLIHIFIFFTHLLLLNYEEIFARESMGFM 448

[Close]

BLAST of Rho GTPase-activating protein vs. Planmine SMEST
Match: SMESG000060252.1 (SMESG000060252.1)

HSP 1 Score: 698.738 bits (1802), Expect = 0.000e+0
Identity = 384/413 (92.98%), Postives = 384/413 (92.98%), Query Frame = 3

Query:  312 MIDHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSRHEXXXXXXXXXXXXXXXXXXNYEEIFARESMGFM 1550
            MIDHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAKVKSKIIKVKKLKELESQFYLDQMVIPEIIKT                             HDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSRHETSFSLIHIFIFFTHLLLLNYEEIFARESMGFM
Sbjct:    1 MIDHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAKVKSKIIKVKKLKELESQFYLDQMVIPEIIKT-----------------------------HDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSRHETSFSLIHIFIFFTHLLLLNYEEIFARESMGFM 384

[Close]

BLAST of Rho GTPase-activating protein vs. Planmine SMEST
Match: SMESG000032128.1 (SMESG000032128.1)

HSP 1 Score: 309.301 bits (791), Expect = 6.493e-99
Identity = 181/464 (39.01%), Postives = 275/464 (59.27%), Query Frame = 3

Query:  144 FDDYEDDFVGTQLTCKMAEENESEFSVGPDTSTLELFDANFEKELGSSNKIFTSQDMIDHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIPPINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAYKQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAXXXXXXXXXXXXXXXXXQFYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPES-QFGVTLQHIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPHLAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSRHEXXXXXXXXXXXXXXXXXXNYEEIFAR 1532
            FD+Y  D  G        ++    F  G  T    L + +FE+ELG + +  + Q++ID +F +I++L ++QVAGDD+ G+KVI+  ACR+P I  IN  R   Y  KTL+Q+V+NDY+L+YFHYG + +N P +K+ML AYK  DR+FKKNLK L++VHP+  +KF+ N   P  SAK   K++ V +L EL+  FY+DQ+ IP+ +K  D              +   +F+N N+  H              S+ ++  +S  K + ++ QF V L +I  ++    +P V+++ + YL+   LE EGIF RS S   +  +++K+D  E ++  +YGDPH+ A +LK FLR L EPL+TFEL+DEI+K+HNL     +   ++++ D LPD NY VL YLI FL EVA HS +N MT  ++  VF  +LIWS+   S + +     F   L+ NY++IF +
Sbjct:   36 FDEYGMDLGGNGEVYYDDDDEFGNFCQGRMTPD-GLIEDDFEEELGCAAQELSVQEVIDSDFPEISRLGILQVAGDDKLGRKVIVFSACRLPFIEQINHQRLLEYIKKTLEQYVTNDYALVYFHYGFSSRNKPSMKWMLQAYKDFDRNFKKNLKALHLVHPSGFIKFMWNLFRPVISAKFGRKVMYVNQLMELDDHFYIDQLPIPQRVKDYD-------TDIMMRKFNIQEFEN-NKPTHS-------------SKTTFMRSSISKEISKTQQFEVPLSYILAHNGGGSLPFVIQKTVTYLQIFGLEVEGIFLRSVSPDTVKRVKEKFDKGEDVNFEDYGDPHVPAVILKIFLRQLTEPLLTFELYDEIVKIHNLPPKNKIIAIKRMIMDYLPDENYEVLNYLITFLTEVAAHSSQNHMTAISLGVVFGANLIWSKQLVSLTTMSFINNFVQHLITNYDDIFVK 477

[Close]

BLAST of Rho GTPase-activating protein vs. Planmine SMEST
Match: SMESG000036427.1 (SMESG000036427.1)

HSP 1 Score: 82.8037 bits (203), Expect = 1.953e-16
Identity = 61/205 (29.76%), Postives = 110/205 (53.66%), Query Frame = 3

Query:  846 INEKDHDMKLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQ----HIKQYHSKCHVPPVMEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDP--HLAACLLKTFLRSLKEPLMTFELHDEIIKL-HNLKTDMAVDLCRQIVCDMLPDYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLI 1439
            INE +H+    S +  D     + Y   S Y       FG  L+    H+K+ ++  +VP ++ +C  Y+R   L+ EGIFR++     ++++++  D   +    E+ +P  H    LLK +LR L EPL+ F  +D +  + + +  +  +DL ++ +  +LP  N+ +LKYL  FL EVA HS+ N M   ++A +F+P+++
Sbjct:   94 INE-NHNKYFLSTNDKDEAQKWIFYLKQSMYLDRGGGLFGTPLRLVLPHLKEEYN--YVPRIIHECCQYIREYGLKEEGIFRKNGQLSLVMQMRELVDRANY----EWDNPDVHTVCSLLKLYLRELPEPLIPFSNYDSLKAVGYRIDANENLDLVKEKL-RLLPVPNHQLLKYLCTFLTEVASHSE-NRMEISSLAKIFSPNIL 289

The following BLAST results are available for this feature:

BLAST of Rho GTPase-activating protein vs. Ensembl Human
BLAST of Rho GTPase-activating protein vs. Ensembl Celegans
BLAST of Rho GTPase-activating protein vs. Ensembl Fly
BLAST of Rho GTPase-activating protein vs. Ensembl Zebrafish
BLAST of Rho GTPase-activating protein vs. Ensembl Xenopus
BLAST of Rho GTPase-activating protein vs. Ensembl Mouse
BLAST of Rho GTPase-activating protein vs. UniProt/SwissProt
BLAST of Rho GTPase-activating protein vs. TrEMBL
BLAST of Rho GTPase-activating protein vs. Ensembl Cavefish
BLAST of Rho GTPase-activating protein vs. Ensembl Sea Lamprey
BLAST of Rho GTPase-activating protein vs. Ensembl Yeast
BLAST of Rho GTPase-activating protein vs. Ensembl Nematostella
BLAST of Rho GTPase-activating protein vs. Ensembl Medaka
BLAST of Rho GTPase-activating protein vs. Planmine SMEST

BLAST of Rho GTPase-activating protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ARHGAP8	3.062e-76	38.40	Rho GTPase activating protein 8 [Source:HGNC Symbo...	[more]
PRR5-ARHGAP8	2.357e-75	38.40	PRR5-ARHGAP8 readthrough [Source:HGNC Symbol;Acc:H...	[more]
ARHGAP1	1.899e-74	36.77	Rho GTPase activating protein 1 [Source:HGNC Symbo...	[more]
PRR5-ARHGAP8	1.457e-72	36.99	PRR5-ARHGAP8 readthrough [Source:HGNC Symbol;Acc:H...	[more]
ARHGAP8	8.792e-70	35.47	Rho GTPase activating protein 8 [Source:HGNC Symbo...	[more]

BLAST of Rho GTPase-activating protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rga-1	1.170e-58	33.86	Rho GTPase Activating protein [Source:UniProtKB/T...	[more]
rga-1	3.194e-29	37.43	Rho GTPase Activating protein [Source:UniProtKB/T...	[more]
rga-1	3.194e-29	37.43	Rho GTPase Activating protein [Source:UniProtKB/T...	[more]
rga-1	3.194e-29	37.43	Rho GTPase Activating protein [Source:UniProtKB/T...	[more]
rga-1	3.194e-29	37.43	Rho GTPase Activating protein [Source:UniProtKB/T...	[more]

BLAST of Rho GTPase-activating protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
RhoGAP68F	2.457e-57	34.34	gene:FBgn0036257 transcript:FBtr0334091	[more]
RhoGAP68F	1.203e-56	34.34	gene:FBgn0036257 transcript:FBtr0334093	[more]
RhoGAP68F	1.295e-56	34.34	gene:FBgn0036257 transcript:FBtr0075997	[more]
RhoGAP68F	1.295e-56	34.34	gene:FBgn0036257 transcript:FBtr0334092	[more]
RhoGAP92B	7.086e-17	30.00	gene:FBgn0038747 transcript:FBtr0344352	[more]

BLAST of Rho GTPase-activating protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
arhgap1	1.844e-71	36.88	Rho GTPase activating protein 1 [Source:ZFIN;Acc:Z...	[more]
arhgap1	1.844e-71	36.88	Rho GTPase activating protein 1 [Source:ZFIN;Acc:Z...	[more]
arhgap17b	8.453e-26	36.75	Rho GTPase activating protein 17b [Source:ZFIN;Acc...	[more]
arhgap17a	1.376e-25	36.75	Rho GTPase activating protein 17a [Source:ZFIN;Acc...	[more]
arhgap17a	1.682e-25	36.75	Rho GTPase activating protein 17a [Source:ZFIN;Acc...	[more]

BLAST of Rho GTPase-activating protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ublcp1	3.506e-67	34.21	ubiquitin like domain containing CTD phosphatase 1...	[more]
ublcp1	4.116e-67	34.30	ubiquitin like domain containing CTD phosphatase 1...	[more]
ublcp1	4.725e-67	34.30	ubiquitin like domain containing CTD phosphatase 1...	[more]
ublcp1	5.038e-64	33.68	ubiquitin like domain containing CTD phosphatase 1...	[more]
ARHGAP17	4.692e-26	36.36	Rho GTPase activating protein 17 [Source:NCBI gene...	[more]

BLAST of Rho GTPase-activating protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Arhgap8	1.133e-74	36.80	Rho GTPase activating protein 8 [Source:MGI Symbol...	[more]
Arhgap8	1.133e-74	36.80	Rho GTPase activating protein 8 [Source:MGI Symbol...	[more]
Arhgap8	1.133e-74	36.80	Rho GTPase activating protein 8 [Source:MGI Symbol...	[more]
Arhgap1	3.786e-74	36.51	Rho GTPase activating protein 1 [Source:MGI Symbol...	[more]
Arhgap1	3.786e-74	36.51	Rho GTPase activating protein 1 [Source:MGI Symbol...	[more]

BLAST of Rho GTPase-activating protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9CXP4\|RHG08_MOUSE	7.928e-74	36.80	Rho GTPase-activating protein 8 OS=Mus musculus OX...	[more]
sp\|Q07960\|RHG01_HUMAN	9.118e-74	36.77	Rho GTPase-activating protein 1 OS=Homo sapiens OX...	[more]
sp\|Q5FWK3\|RHG01_MOUSE	2.648e-73	36.51	Rho GTPase-activating protein 1 OS=Mus musculus OX...	[more]
sp\|P85298\|RHG08_HUMAN	4.222e-69	35.47	Rho GTPase-activating protein 8 OS=Homo sapiens OX...	[more]
sp\|Q9VTU3\|RG68F_DROME	1.298e-55	34.34	Rho GTPase-activating protein 68F OS=Drosophila me...	[more]

BLAST of Rho GTPase-activating protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A267EB39	4.420e-100	39.96	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A267FHB0	7.835e-100	40.89	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A267FCW5	1.930e-99	41.03	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A1I8HPU5	5.365e-99	40.43	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A267DWH9	2.834e-98	41.39	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]

BLAST of Rho GTPase-activating protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ARHGAP8	6.824e-71	35.73	Rho GTPase activating protein 8 [Source:NCBI gene;...	[more]
arhgap1	2.535e-67	36.77	Rho GTPase activating protein 1 [Source:NCBI gene;...	[more]
arhgap1	8.537e-61	35.84	Rho GTPase activating protein 1 [Source:NCBI gene;...	[more]
arhgap1	8.749e-59	32.80	Rho GTPase activating protein 1 [Source:NCBI gene;...	[more]
ARHGAP17	1.405e-26	37.35	Rho GTPase activating protein 17 [Source:NCBI gene...	[more]

BLAST of Rho GTPase-activating protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000002340.1	9.659e-75	38.10	pep scaffold:Pmarinus_7.0:GL481985:13400:22843:-1 ...	[more]
ENSPMAT00000006125.1	5.416e-28	36.08	pep scaffold:Pmarinus_7.0:GL477389:161447:166370:-...	[more]
ralbp1	3.270e-19	35.58	ralA binding protein 1 [Source:ZFIN;Acc:ZDB-GENE-0...	[more]
si:ch211-247j9.1	5.705e-18	31.47	si:ch211-247j9.1 [Source:ZFIN;Acc:ZDB-GENE-091204-...	[more]
ENSPMAT00000005293.1	6.291e-16	33.80	pep scaffold:Pmarinus_7.0:GL478264:159922:165142:-...	[more]

BLAST of Rho GTPase-activating protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
RGA1	1.278e-12	28.16	GTPase-activating protein for polarity-establishme...	[more]
BAG7	1.057e-11	28.88	Rho GTPase activating protein (RhoGAP); stimulates...	[more]
LRG1	1.981e-11	27.67	GTPase-activating protein (GAP); contains Rho1p-sp...	[more]
RGD1	5.947e-9	26.51	GTPase-activating protein (RhoGAP) for Rho3p and R...	[more]
BEM3	5.949e-9	27.01	Rho GTPase activating protein (RhoGAP); involved i...	[more]

BLAST of Rho GTPase-activating protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO47995	2.847e-22	37.65	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO42235	8.431e-20	36.24	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO46865	2.258e-17	28.49	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO47842	4.515e-17	34.38	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49778	3.982e-16	33.74	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Rho GTPase-activating protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSORLT00000024110.2	3.364e-72	38.36	Rho GTPase activating protein 1 [Source:NCBI gene;...	[more]
ARHGAP8	7.637e-58	33.59	Rho GTPase activating protein 8 [Source:NCBI gene;...	[more]
arhgap17a	1.702e-25	37.35	Rho GTPase activating protein 17 [Source:NCBI gene...	[more]
arhgap17a	1.878e-25	37.35	Rho GTPase activating protein 17 [Source:NCBI gene...	[more]
arhgap17a	1.924e-25	37.35	Rho GTPase activating protein 17 [Source:NCBI gene...	[more]

BLAST of Rho GTPase-activating protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000060252.1	0.000e+0	99.79	SMESG000060252.1	[more]
SMESG000060252.1	0.000e+0	93.92	SMESG000060252.1	[more]
SMESG000060252.1	0.000e+0	92.98	SMESG000060252.1	[more]
SMESG000032128.1	6.493e-99	39.01	SMESG000032128.1	[more]
SMESG000036427.1	1.953e-16	29.76	SMESG000036427.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30021616 ID=SMED30021616|Name=Rho GTPase-activating protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1749bp
GTTGTTTGATAATTTAACTTAGTAATTTGTGATTATTCAAACATTGTTAC
TTAATAGTGTTTATTGTACTTTATTAGTATTTGTATGTACTGTAATTGAA
ATTTCGAAAAAAAAATTAAATGACTGACCTCGAGGGATCAACATTTGATG
ATTATGAAGATGATTTTGTTGGAACACAATTAACTTGTAAAATGGCAGAA
GAAAATGAATCAGAATTCTCAGTTGGTCCAGATACAAGCACTTTAGAATT
ATTCGACGCAAATTTTGAAAAAGAATTAGGATCATCTAATAAGATATTCA
CATCTCAAGATATGATCGACCATGAATTCAGTGACATTGCAAAGCTTAAT
GTGGTTCAAGTGGCTGGAGATGACAGATTTGGAAAGAAAGTCATAATAAT
CTATGCCTGCAGAATACCCCCCATTAATACTATTAATCTCGATAGATTTT
GGGCGTACACTGTCAAAACTCTGAAGCAATTCGTATCAAATGATTACTCT
TTGATTTATTTCCATTACGGATTGACGGATAAAAATAATCCTGGCATCAA
ATTCATGCTTAACGCCTACAAGCAAATTGACAGAGATTTCAAAAAGAATT
TGAAAAATCTTTATATAGTTCATCCAACCAATCTATTGAAATTTATTATT
AATGCACTATTGCCATTCTTCAGTGCAAAAGTTAAAAGCAAAATTATCAA
AGTGAAGAAACTGAAAGAACTTGAAAGTCAATTCTATTTAGATCAAATGG
TTATTCCAGAAATTATTAAAACACAAGACAGATTCAGGAATTCAGTTGGT
CAATCTCAGCGGCCTCATACATGGAAATTCGATGACTTTAAAAATATCAA
TGAAAAGGATCATGATATGAAACTCGACTCCCCCAGTTCTGGCGATAATA
TCTATTCACAGGTTTCTTATCCAAATACTTCCTTTTACAAAGCTTTACCA
GAATCACAATTTGGAGTTACTTTGCAGCACATTAAACAATATCACTCCAA
ATGTCACGTGCCGCCGGTGATGGAACAGTGTATCATGTACTTGAGAAGCG
AATGTCTTGAATGCGAAGGAATCTTTCGCCGGAGTGCTTCTAAACTTAAA
TTATTAGAAATTCAAAAAAAATATGATTTGAATGAACACATAGATTTATC
AGAATATGGCGATCCTCATTTAGCAGCTTGTTTATTGAAAACATTCCTTA
GGTCACTCAAAGAGCCATTGATGACTTTTGAATTACACGATGAAATTATC
AAACTTCACAACCTGAAGACTGATATGGCTGTGGATTTATGTCGTCAAAT
TGTATGTGACATGCTCCCAGATTACAATTATCATGTTCTGAAATATCTGA
TTGAATTTCTTATTGAGGTCGCTGAGCATTCCGACAAAAATATGATGACA
TTCCAAAATATAGCCAATGTATTCGCCCCCAGCTTGATATGGTCGAGGCA
TGAGACTTCATTTTCACTTATTCACATTTTCATTTTCTTCACCCATCTTT
TATTGTTAAATTATGAAGAGATATTCGCAAGAGAATCAATGGGTTTCATG
TGATGAAATATAATTAATTTTCACTTTTTGCAGTGACCTAACAGCAATTG
TTCACATTTTCTATTTTTGAATAACTATTTTGTTATACTTATACTTTGTT
TATAAGTAATTTTCTTACAGCTTATTCAAAAGTTGGCTGATTAAGATTTT
CATCTATTTATTGTTTTGTGTTGTTTAAATATAGCCAGCTTTAATCTTG

protein sequence of SMED30021616-orf-1

>SMED30021616-orf-1 ID=SMED30021616-orf-1|Name=SMED30021616-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=478bp
MTDLEGSTFDDYEDDFVGTQLTCKMAEENESEFSVGPDTSTLELFDANFE
KELGSSNKIFTSQDMIDHEFSDIAKLNVVQVAGDDRFGKKVIIIYACRIP
PINTINLDRFWAYTVKTLKQFVSNDYSLIYFHYGLTDKNNPGIKFMLNAY
KQIDRDFKKNLKNLYIVHPTNLLKFIINALLPFFSAKVKSKIIKVKKLKE
LESQFYLDQMVIPEIIKTQDRFRNSVGQSQRPHTWKFDDFKNINEKDHDM
KLDSPSSGDNIYSQVSYPNTSFYKALPESQFGVTLQHIKQYHSKCHVPPV
MEQCIMYLRSECLECEGIFRRSASKLKLLEIQKKYDLNEHIDLSEYGDPH
LAACLLKTFLRSLKEPLMTFELHDEIIKLHNLKTDMAVDLCRQIVCDMLP
DYNYHVLKYLIEFLIEVAEHSDKNMMTFQNIANVFAPSLIWSRHETSFSL
IHIFIFFTHLLLLNYEEIFARESMGFM*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000016	pharynx
PLANA:0000020	protonephridia
PLANA:0000026	gut
PLANA:0000034	epidermis
PLANA:0000070	intestinal phagocyte
PLANA:0000099	neuron
PLANA:0002032	epidermal cell
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036865	CRAL-TRIO_dom_sf
IPR000198	RhoGAP_dom
IPR001251	CRAL-TRIO_dom
IPR008936	Rho_GTPase_activation_prot

Vocabulary: **biological process**
Term	Definition
GO:0007165	signal transduction

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR000198	Rho GTPase-activating protein domain	SMART	SM00324	RhoGAP_3	coord: 295..466 e-value: 3.0E-47 score: 172.9
IPR000198	Rho GTPase-activating protein domain	PFAM	PF00620	RhoGAP	coord: 298..445 e-value: 2.0E-39 score: 134.8
IPR000198	Rho GTPase-activating protein domain	PROSITE	PS50238	RHOGAP	coord: 283..469 score: 36.812
IPR001251	CRAL-TRIO lipid binding domain	SMART	SM00516	sec14_4	coord: 72..221 e-value: 2.6E-7 score: 40.3
IPR001251	CRAL-TRIO lipid binding domain	PFAM	PF13716	CRAL_TRIO_2	coord: 88..216 e-value: 4.8E-26 score: 91.6
IPR001251	CRAL-TRIO lipid binding domain	PROSITE	PS50191	CRAL_TRIO	coord: 69..224 score: 8.76
IPR001251	CRAL-TRIO lipid binding domain	CDD	cd00170	SEC14	coord: 67..185 e-value: 7.06902E-13 score: 64.3286
IPR036865	CRAL-TRIO lipid binding domain superfamily	GENE3D	G3DSA:3.40.525.10		coord: 67..210 e-value: 8.4E-37 score: 128.1
IPR036865	CRAL-TRIO lipid binding domain superfamily	SUPERFAMILY	SSF52087	CRAL/TRIO domain	coord: 69..210
IPR008936	Rho GTPase activation protein	GENE3D	G3DSA:1.10.555.10		coord: 211..474 e-value: 4.1E-54 score: 185.4
IPR008936	Rho GTPase activation protein	SUPERFAMILY	SSF48350	GTPase activation domain, GAP	coord: 277..469
None	No IPR available	PANTHER	PTHR45808:SF4	PRR5-ARHGAP8 READTHROUGH-RELATED	coord: 248..472 coord: 65..232
None	No IPR available	PANTHER	PTHR45808	FAMILY NOT NAMED	coord: 248..472 coord: 65..232