Nesprin-1
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30021613 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 51Note: Hover over icons to view figure legend
Homology
BLAST of Nesprin-1 vs. Ensembl Human
Match: SYNE1 (spectrin repeat containing nuclear envelope protein 1 [Source:HGNC Symbol;Acc:HGNC:17089]) HSP 1 Score: 258.07 bits (658), Expect = 2.813e-72 Identity = 202/594 (34.01%), Postives = 315/594 (53.03%), Query Frame = 2
Query: 185 LKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXX------------XXXXALGMANDPN--------AKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNELDIVKDFNDKVDKNFENLNSKNNYDIFADLMSQ----RDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLMEPFP--NVHDKTFNDKVLQKLKEHESIFNKKNDVLAKFREVLQNPPAN---ISPKQLEAMKTRMENVCKAEGPVREKLNIFGIQANLKNKAQKWAVDLNSWDSPIQSKQDLLDKIEQFNISMENGTSMDKFTSQLDELVKRKVKFCKENPVLD--EDLLNFINKAINECEEENDILPEKFESTLMKLENLSSEWD 1873
L+DEQE +QK+TFTKW+NS+L ++KPP+++ DL +D+ DG+ LL LLE+L+ L E+ + M++IH ++NI TAL+F+E +KIKLVNIN +D+ DG+P+IVLGL+WT IL+FQIEE + ++ + P+ K++G AKK L+ W + G+ +KDFG+SW G AF++++H I P LV++E ++ +N+E LE+AF IAE ELGIP+LLD EDVDV+KPDEKSIMTYVAQFLK YP+ +E E M ++ I + D N ++ Y F Q R ++ L+ + D L LD V+Q +D+ +L +W LDK LP LG+ IG+WL AE +L E VH++T N + +KL++H+ + + F E+ + N + P QLE M R V K+ ++ L + L SW ++ + ++ + +EN +++ L + + K + ++ E+++ F+N+ + L + S LE + S WD
Sbjct: 21 LQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGVKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEG-RKIKLVNINSTDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSIVSSETPSPPSKRKVTTKIQGNAKKALLKWVQYTAGKQTGIEVKDFGKSWRSGVAFHSVIHAIRPELVDLETVKGRSNRENLEDAFTIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDIHNASTDGQEDDREDRVIFKEM-----KVWIEQFERDLTRAQMVESNLQDKYQSFKHFRVQYEMKRKQIEHLIQPLHRDGKLSLDQALVKQ---SWDRVTSRLFDWHIQLDKSLPAPLGT-IGAWLYRAEVALREEITVQQVHEETANT-IQRKLEQHKDLLQNTDAHKRAFHEIYRTRSVNGIPVPPDQLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRESVEQLLQNYVSFIENSKFFEQYEVTYQILKQTAEMYVKADGSVEEAENVMKFMNETTAQWRN----LSVEVRSVRSMLEEVISNWD 599
BLAST of Nesprin-1 vs. Ensembl Human
Match: SYNE1 (spectrin repeat containing nuclear envelope protein 1 [Source:HGNC Symbol;Acc:HGNC:17089]) HSP 1 Score: 257.684 bits (657), Expect = 6.240e-71 Identity = 207/625 (33.12%), Postives = 324/625 (51.84%), Query Frame = 2
Query: 161 TVVKKGVLLKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKK------IKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXX------------XXXXALGMANDPN--------AKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNELD-----IVKDFNDKVDKNFENL--------NSKNNYDIFADLMSQ----RDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLMEPFP--NVHDKTFNDKVLQKLKEHESIFNKKNDVLAKFREVLQNPPAN---ISPKQLEAMKTRMENVCKAEGPVREKLNIFGIQANLKNKAQKWAVDLNSWDSPIQSKQDLLDKIEQFNISMENGTSMDKFTSQLDELVKRKVKFCKENPVLD--EDLLNFINKAINECEEENDILPEKFESTLMKLENLSSEWDEISD 1885
T+ K ++KDEQE +QK+TFTKW+NS+L ++KPP+++ DL +D+ DG+ LL LLE+L+ L E+ + M++IH ++NI TAL+F+E K IKLVNIN +D+ DG+P+IVLGL+WT IL+FQIEE + ++ + P+ K++G AKK L+ W + G+ +KDFG+SW G AF++++H I P LV++E ++ +N+E LE+AF IAE ELGIP+LLD EDVDV+KPDEKSIMTYVAQFLK YP+ +E EI G S I K+ +++ +L N ++ Y F Q R ++ L+ + D L LD V+Q +D+ +L +W LDK LP LG+ IG+WL AE +L E VH++T N + +KL++H+ + + F E+ + N + P QLE M R V K+ ++ L + L SW ++ + ++ + +EN +++ L + + K + ++ E+++ F+N+ + L + S LE + S WD +
Sbjct: 4 TIYKTPGMIKDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGVKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEGRKSMHRGSPIKLVNINSTDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSIVSSETPSPPSKRKVTTKIQGNAKKALLKWVQYTAGKQTGIEVKDFGKSWRSGVAFHSVIHAIRPELVDLETVKGRSNRENLEDAFTIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDIHNASTDGQE-DDEILPGFPSFANSVQNFKREDRVIFKEMKVWIEQFERDLTRAQMVESNLQDKYQSFKHFRVQYEMKRKQIEHLIQPLHRDGKLSLDQALVKQ---SWDRVTSRLFDWHIQLDKSLPAPLGT-IGAWLYRAEVALREEITVQQVHEETANT-IQRKLEQHKDLLQNTDAHKRAFHEIYRTRSVNGIPVPPDQLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRESVEQLLQNYVSFIENSKFFEQYEVTYQILKQTAEMYVKADGSVEEAENVMKFMNETTAQWRN----LSVEVRSVRSMLEEVISNWDRYGN 618
BLAST of Nesprin-1 vs. Ensembl Human
Match: SYNE1 (spectrin repeat containing nuclear envelope protein 1 [Source:HGNC Symbol;Acc:HGNC:17089]) HSP 1 Score: 257.684 bits (657), Expect = 6.423e-71 Identity = 205/611 (33.55%), Postives = 321/611 (52.54%), Query Frame = 2
Query: 185 LKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXX------------XXXXALGMANDPN--------AKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNELD-----IVKDFNDKVDKNFENL--------NSKNNYDIFADLMSQ----RDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLMEPFP--NVHDKTFNDKVLQKLKEHESIFNKKNDVLAKFREVLQNPPAN---ISPKQLEAMKTRMENVCKAEGPVREKLNIFGIQANLKNKAQKWAVDLNSWDSPIQSKQDLLDKIEQFNISMENGTSMDKFTSQLDELVKRKVKFCKENPVLD--EDLLNFINKAINECEEENDILPEKFESTLMKLENLSSEWDEISD 1885
L+DEQE +QK+TFTKW+NS+L ++KPP+++ DL +D+ DG+ LL LLE+L+ L E+ + M++IH ++NI TAL+F+E +KIKLVNIN +D+ DG+P+IVLGL+WT IL+FQIEE + ++ + P+ K++G AKK L+ W + G+ +KDFG+SW G AF++++H I P LV++E ++ +N+E LE+AF IAE ELGIP+LLD EDVDV+KPDEKSIMTYVAQFLK YP+ +E EI G S I K+ +++ +L N ++ Y F Q R ++ L+ + D L LD V+Q +D+ +L +W LDK LP LG+ IG+WL AE +L E VH++T N + +KL++H+ + + F E+ + N + P QLE M R V K+ ++ L + L SW ++ + ++ + +EN +++ L + + K + ++ E+++ F+N+ + L + S LE + S WD +
Sbjct: 21 LQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGVKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEG-RKIKLVNINSTDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSIVSSETPSPPSKRKVTTKIQGNAKKALLKWVQYTAGKQTGIEVKDFGKSWRSGVAFHSVIHAIRPELVDLETVKGRSNRENLEDAFTIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDIHNASTDGQE-DDEILPGFPSFANSVQNFKREDRVIFKEMKVWIEQFERDLTRAQMVESNLQDKYQSFKHFRVQYEMKRKQIEHLIQPLHRDGKLSLDQALVKQ---SWDRVTSRLFDWHIQLDKSLPAPLGT-IGAWLYRAEVALREEITVQQVHEETANT-IQRKLEQHKDLLQNTDAHKRAFHEIYRTRSVNGIPVPPDQLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRESVEQLLQNYVSFIENSKFFEQYEVTYQILKQTAEMYVKADGSVEEAENVMKFMNETTAQWRN----LSVEVRSVRSMLEEVISNWDRYGN 620
BLAST of Nesprin-1 vs. Ensembl Human
Match: SYNE1 (spectrin repeat containing nuclear envelope protein 1 [Source:HGNC Symbol;Acc:HGNC:17089]) HSP 1 Score: 243.047 bits (619), Expect = 1.424e-68 Identity = 177/445 (39.78%), Postives = 259/445 (58.20%), Query Frame = 2
Query: 185 LKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKK------IKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXX------------XXXXALGMANDPN--------AKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNELD-----IVKDFNDKVDKNFENL--------NSKNNYDIFADLMSQ----RDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLMEPFP--NVHDKTFNDKVLQKLKEHESI 1384
L+DEQE +QK+TFTKW+NS+L ++KPP+++ DL +D+ DG+ LL LLE+L+ L E+ + M++IH ++NI TAL+F+E K IKLVNIN +D+ DG+P+IVLGL+WT IL+FQIEE + ++ + P+ K++G AKK L+ W + G+ +KDFG+SW G AF++++H I P LV++E ++ +N+E LE+AF IAE ELGIP+LLD EDVDV+KPDEKSIMTYVAQFLK YP+ +E EI G S I K+ +++ +L N ++ Y F Q R ++ L+ + D L LD V+Q +D+ +L +W LDK LP LG+ IG+WL AE +L E VH++T N + +KL++H+ I
Sbjct: 4 LQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGVKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEGRKSMHRGSPIKLVNINSTDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSIVSSETPSPPSKRKVTTKIQGNAKKALLKWVQYTAGKQTGIEVKDFGKSWRSGVAFHSVIHAIRPELVDLETVKGRSNRENLEDAFTIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDIHNASTDGQE-DDEILPGFPSFANSVQNFKREDRVIFKEMKVWIEQFERDLTRAQMVESNLQDKYQSFKHFRVQYEMKRKQIEHLIQPLHRDGKLSLDQALVKQ---SWDRVTSRLFDWHIQLDKSLPAPLGT-IGAWLYRAEVALREEITVQQVHEETANT-IQRKLEQHKKI 442
BLAST of Nesprin-1 vs. Ensembl Human
Match: SYNE1 (spectrin repeat containing nuclear envelope protein 1 [Source:HGNC Symbol;Acc:HGNC:17089]) HSP 1 Score: 257.684 bits (657), Expect = 6.609e-68 Identity = 204/608 (33.55%), Postives = 318/608 (52.30%), Query Frame = 2
Query: 161 TVVKKGVLLKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKK------IKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXX------------XXXXALGMANDPN--------AKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNELDIVKDFNDKVDKNFENLNSKNNYDIFADLMSQ----RDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLMEPFP--NVHDKTFNDKVLQKLKEHESIFNKKNDVLAKFREVLQNPPAN---ISPKQLEAMKTRMENVCKAEGPVREKLNIFGIQANLKNKAQKWAVDLNSWDSPIQSKQDLLDKIEQFNISMENGTSMDKFTSQLDELVKRKVKFCKENPVLD--EDLLNFINKAINECEEENDILPEKFESTLMKLENLSSEWD 1873
T+ K ++KDEQE +QK+TFTKW+NS+L ++KPP+++ DL +D+ DG+ LL LLE+L+ L E+ + M++IH ++NI TAL+F+E K IKLVNIN +D+ DG+P+IVLGL+WT IL+FQIEE + ++ + P+ K++G AKK L+ W + G+ +KDFG+SW G AF++++H I P LV++E ++ +N+E LE+AF IAE ELGIP+LLD EDVDV+KPDEKSIMTYVAQFLK YP+ +E E M ++ I + D N ++ Y F Q R ++ L+ + D L LD V+Q +D+ +L +W LDK LP LG+ IG+WL AE +L E VH++T N + +KL++H+ + + F E+ + N + P QLE M R V K+ ++ L + L SW ++ + ++ + +EN +++ L + + K + ++ E+++ F+N+ + L + S LE + S WD
Sbjct: 4 TIYKTPGMIKDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGVKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEGRKSMHRGSPIKLVNINSTDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSIVSSETPSPPSKRKVTTKIQGNAKKALLKWVQYTAGKQTGIEVKDFGKSWRSGVAFHSVIHAIRPELVDLETVKGRSNRENLEDAFTIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDIHNASTDGQEDDREDRVIFKEM-----KVWIEQFERDLTRAQMVESNLQDKYQSFKHFRVQYEMKRKQIEHLIQPLHRDGKLSLDQALVKQ---SWDRVTSRLFDWHIQLDKSLPAPLGT-IGAWLYRAEVALREEITVQQVHEETANT-IQRKLEQHKDLLQNTDAHKRAFHEIYRTRSVNGIPVPPDQLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRESVEQLLQNYVSFIENSKFFEQYEVTYQILKQTAEMYVKADGSVEEAENVMKFMNETTAQWRN----LSVEVRSVRSMLEEVISNWD 597
BLAST of Nesprin-1 vs. Ensembl Celegans
Match: unc-70 (Spectrin beta chain [Source:UniProtKB/TrEMBL;Acc:E0AHA7]) HSP 1 Score: 142.124 bits (357), Expect = 8.890e-33 Identity = 99/293 (33.79%), Postives = 156/293 (53.24%), Query Frame = 2
Query: 185 LKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXXXXXALGMANDPNAKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNELDIVKDFNDKVDKNFENLNS 1063
L+DE+E +QKKTFTKW+NS+L + + + +L L + + +IHCL N+ L+F+ N + + L N+ D+VDG + LGL+WT IL FQI++ + + N + + AK+ L+ W + +N+K+F SW DG AFNAL+H P LV+ + ++K L++AF+ AEN+LG+ K LD+EDV+V++PDEKSI+TYV + Y K +NI + ++ + LM NDK+ +E L+S
Sbjct: 103 LRDERELVQKKTFTKWVNSHLVRVSCKV---QDLYMDMRDGKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRN-QHVHLENLGSHDIVDGNSRLTLGLIWTIILRFQIQD--------ITFEDADNHETRS-AKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSIITYVVTYY-HYFNKLKQDNIQGKRIGKVINELME--------------NDKMINRYETLSS 367
BLAST of Nesprin-1 vs. Ensembl Celegans
Match: unc-70 (Spectrin beta chain [Source:UniProtKB/TrEMBL;Acc:E0AHA7]) HSP 1 Score: 140.969 bits (354), Expect = 1.870e-32 Identity = 99/293 (33.79%), Postives = 155/293 (52.90%), Query Frame = 2
Query: 185 LKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXXXXXALGMANDPNAKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNELDIVKDFNDKVDKNFENLNS 1063
L DE+E +QKKTFTKW+NS+L + + + +L L + + +IHCL N+ L+F+ N + + L N+ D+VDG + LGL+WT IL FQI++ + + N + + AK+ L+ W + +N+K+F SW DG AFNAL+H P LV+ + ++K L++AF+ AEN+LG+ K LD+EDV+V++PDEKSI+TYV + Y K +NI + ++ + LM NDK+ +E L+S
Sbjct: 34 LADERELVQKKTFTKWVNSHLVRVSCKV---QDLYMDMRDGKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRN-QHVHLENLGSHDIVDGNSRLTLGLIWTIILRFQIQD--------ITFEDADNHETRS-AKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSIITYVVTYY-HYFNKLKQDNIQGKRIGKVINELME--------------NDKMINRYETLSS 298
BLAST of Nesprin-1 vs. Ensembl Celegans
Match: unc-70 (Spectrin beta chain [Source:UniProtKB/TrEMBL;Acc:E0AHA7]) HSP 1 Score: 140.584 bits (353), Expect = 2.318e-32 Identity = 99/293 (33.79%), Postives = 155/293 (52.90%), Query Frame = 2
Query: 185 LKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXXXXXALGMANDPNAKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNELDIVKDFNDKVDKNFENLNS 1063
L DE+E +QKKTFTKW+NS+L + + + +L L + + +IHCL N+ L+F+ N + + L N+ D+VDG + LGL+WT IL FQI++ + + N + + AK+ L+ W + +N+K+F SW DG AFNAL+H P LV+ + ++K L++AF+ AEN+LG+ K LD+EDV+V++PDEKSI+TYV + Y K +NI + ++ + LM NDK+ +E L+S
Sbjct: 34 LADERELVQKKTFTKWVNSHLVRVSCKV---QDLYMDMRDGKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRN-QHVHLENLGSHDIVDGNSRLTLGLIWTIILRFQIQD--------ITFEDADNHETRS-AKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSIITYVVTYY-HYFNKLKQDNIQGKRIGKVINELME--------------NDKMINRYETLSS 298
BLAST of Nesprin-1 vs. Ensembl Celegans
Match: unc-70 (Spectrin beta chain [Source:UniProtKB/TrEMBL;Acc:E0AHA7]) HSP 1 Score: 140.584 bits (353), Expect = 2.364e-32 Identity = 99/293 (33.79%), Postives = 155/293 (52.90%), Query Frame = 2
Query: 185 LKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXXXXXALGMANDPNAKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNELDIVKDFNDKVDKNFENLNS 1063
L DE+E +QKKTFTKW+NS+L + + + +L L + + +IHCL N+ L+F+ N + + L N+ D+VDG + LGL+WT IL FQI++ + + N + + AK+ L+ W + +N+K+F SW DG AFNAL+H P LV+ + ++K L++AF+ AEN+LG+ K LD+EDV+V++PDEKSI+TYV + Y K +NI + ++ + LM NDK+ +E L+S
Sbjct: 34 LADERELVQKKTFTKWVNSHLVRVSCKV---QDLYMDMRDGKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRN-QHVHLENLGSHDIVDGNSRLTLGLIWTIILRFQIQD--------ITFEDADNHETRS-AKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSIITYVVTYY-HYFNKLKQDNIQGKRIGKVINELME--------------NDKMINRYETLSS 298
BLAST of Nesprin-1 vs. Ensembl Celegans
Match: vab-10 (VAB-10B protein [Source:UniProtKB/TrEMBL;Acc:G5EFM4]) HSP 1 Score: 125.561 bits (314), Expect = 9.841e-28 Identity = 85/275 (30.91%), Postives = 134/275 (48.73%), Query Frame = 2
Query: 191 DEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTA---------XXXXXXXXXXXXXXXALGMANDPNAKVKGQ----AKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGT--NKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQF---LKSYPEGKKPENISEEITAE 961
DE++ +QKKTFTKW+N +L + I + + + T + +K + H + N++ L+F++ K IKLVNI P D+V+G + LGL+WT +E + + A + + G A+ L+ W + +N+ +F SW DG AFNA++H + ++ +I + N ERL NAF A+ E G+ +LLD+EDVD PDEKSI+TYV+ L PE + + + EE E
Sbjct: 35 DERDNVQKKTFTKWVNKHLSKTDHKI----DDLFVDLRDGYALIALLEALTGERIQKENGYTRFHRIQNVQYCLDFLKK-KNIKLVNIRPEDIVEGNGKLTLGLIWTIILNFQVSVIRQRLLLESSQHEQMSAKHTTTNSQVSLHGSDATSARDALLQWARRVTAGYPRVNVNNFSSSWRDGLAFNAILHRYRSSAIDWNKISSDSVSNTERLNNAFAAADREFGVERLLDAEDVDTNNPDEKSIITYVSSLYNALPHEPEMSRLQKVQEEYIEE 304
BLAST of Nesprin-1 vs. Ensembl Fly
Match: Msp300 (gene:FBgn0261836 transcript:FBtr0332404) HSP 1 Score: 253.062 bits (645), Expect = 4.933e-66 Identity = 176/469 (37.53%), Postives = 268/469 (57.14%), Query Frame = 2
Query: 185 LKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAX---XXXXXXXXXXXXXXALG--------MANDPNAKVKGQ-----AKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNELDIVKDFNDKVDKNFENLNSKNNYDIFADLMSQRDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLME-PFPNVHDKTFNDKVLQKLKEHESIFNKKNDVLAKFREVLQNPPANISP-KQLEAMKTRMENVCKAEGPVREKLNIF 1537
L++EQE++QKKTFT W+NSYL ++ PP+ I DL+ DL DG L+ LLE+L+ L EK + +++ H LSN TAL+F+ + K+IKLVNINP+D+VDG+P +VLGL+WT I + E+L +G + N + +K + A+K L+ W NAL G+ +KDFG SW DG AF AL+ I LVN+ E++K +N++RLE AF++AE++LGI KLLD+EDVDV KPDEKSIMTYVAQFL YPE K + E + +V+ E + + + E L +++ D ++ + +K L++ S +L + ++ + + + ++ W W LD LPG G+ +G WL +AE+ LM+ PN ++ + +KL+EH+ F +LA F ++P A P +QL M+ R++ V R +L
Sbjct: 265 LQEEQERVQKKTFTNWINSYLLKRVPPLRIDDLINDLRDGTKLIALLEVLSGERLPVEKGRVLRRPHFLSNANTALQFLAS-KRIKLVNINPADLVDGRPPVVLGLIWTIILYFQIEENSRNLEYLGHGIGGSVSSLDSVGNQKHGDLKAEKWKQGARKTLLNWVTNALPKDSGVEVKDFGASWRDGVAFLALIDAIKANLVNLAELKKTSNRQRLETAFDVAESKLGIAKLLDAEDVDVPKPDEKSIMTYVAQFLHKYPEPKGASRDQSHVQQEADELRRFLVEKTTEYEPMVMMSSFPRDFGEYLLARSEVDAH---LAAYNRLKQLIESQS--GFLQVSRQSWEEINELWQRLQYQMMYWLWLLDSELPGDFGT-VGKWLAEAEKLLMDNDIPNAMNEETAAVISRKLEEHKLFFADLPRILAMFDNAKRSPVAQQIPLEQLRNMERRLQEVGPKAAERRIRLKFL 726 HSP 2 Score: 53.9138 bits (128), Expect = 6.514e-6 Identity = 84/374 (22.46%), Postives = 162/374 (43.32%), Query Frame = 2
Query: 11141 YNVLFNKCQNECDKCDHLIKLMTKYEISRADVLHWIEASTQTLLKCS---DYTLKQSQMKSKLLMIDNLEKELENYGQSKFVEAIQDGEELLGELAGMPMQ-IVQQQMADLKSDWMEISRQLNQLSSNLRNTTSRSEAFKEMSNRLSNWLDDIEHTGLMDLSHIEHQCEIPFESGNSSSKHDRAKTLLTELNRHKQDFLQLANLATELANPSFDIENSQIQNRYIRLSNNLKDKIEKLNKQQADYDQIKQDIEEMEKWVFQTSIRIINENA---EQGKTTNNTIQEIETLIKHSNEIIANILSQEPEIVKIGQAVDSLINISNNKNSDKEKELQDDLSKLIENFNNLKSSSIHKRDHLKDSVKKWDTYQDFLQS 12241
Y L Q K + + T++ + ++ WIE + Q L CS D + + KL +++L L GQ + +QD + Q +++ M ++ DW + + Q S+L+ +R F ++L WL++ E T ++ E E + +R KTL EL + QL + A +L D N ++Q+R +L N+ I L ++ DY+ Q ++++EKW+ Q S +++ N+ + T I++ E L+ + N+ ++ GQA I + ++ L + +++N+L +S+ ++ L +S+ K+ Y+D L S
Sbjct: 5834 YTKLLTSAQGLVAKIEKNLSDHTEFLNYKKEMDAWIEKAQQVLDDCSTDGDAAI----IAQKLDTVNSLASRLPE-GQ-HLLALVQDAYSKASNITPEDKQEKLRELMTKVREDWDALGLAVKQKLSDLKQAQNRWNDFAANKDKLEKWLNETETT-------LKVAPETKGELSEMKTLLERYKTLSNELKLKGNELEQLQSEARDLGT-EVDAVN-RLQSRCDKLKNDCSAHITALEQEMFDYNAYHQSLQDVEKWLLQISFQLMAHNSLFISNREQTQEQIKQHEALLVEIQKYQTNL----DDLNAKGQAQ---IKRYESSTPAIRPTVESQLKNIQDSYNSLLQTSVQIKNRLLESLAKFQEYEDTLDS 6185
BLAST of Nesprin-1 vs. Ensembl Fly
Match: Msp300 (gene:FBgn0261836 transcript:FBtr0303388) HSP 1 Score: 252.677 bits (644), Expect = 5.643e-66 Identity = 176/469 (37.53%), Postives = 268/469 (57.14%), Query Frame = 2
Query: 185 LKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAX---XXXXXXXXXXXXXXALG--------MANDPNAKVKGQ-----AKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNELDIVKDFNDKVDKNFENLNSKNNYDIFADLMSQRDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLME-PFPNVHDKTFNDKVLQKLKEHESIFNKKNDVLAKFREVLQNPPANISP-KQLEAMKTRMENVCKAEGPVREKLNIF 1537
L++EQE++QKKTFT W+NSYL ++ PP+ I DL+ DL DG L+ LLE+L+ L EK + +++ H LSN TAL+F+ + K+IKLVNINP+D+VDG+P +VLGL+WT I + E+L +G + N + +K + A+K L+ W NAL G+ +KDFG SW DG AF AL+ I LVN+ E++K +N++RLE AF++AE++LGI KLLD+EDVDV KPDEKSIMTYVAQFL YPE K + E + +V+ E + + + E L +++ D ++ + +K L++ S +L + ++ + + + ++ W W LD LPG G+ +G WL +AE+ LM+ PN ++ + +KL+EH+ F +LA F ++P A P +QL M+ R++ V R +L
Sbjct: 265 LQEEQERVQKKTFTNWINSYLLKRVPPLRIDDLINDLRDGTKLIALLEVLSGERLPVEKGRVLRRPHFLSNANTALQFLAS-KRIKLVNINPADLVDGRPPVVLGLIWTIILYFQIEENSRNLEYLGHGIGGSVSSLDSVGNQKHGDLKAEKWKQGARKTLLNWVTNALPKDSGVEVKDFGASWRDGVAFLALIDAIKANLVNLAELKKTSNRQRLETAFDVAESKLGIAKLLDAEDVDVPKPDEKSIMTYVAQFLHKYPEPKGASRDQSHVQQEADELRRFLVEKTTEYEPMVMMSSFPRDFGEYLLARSEVDAH---LAAYNRLKQLIESQS--GFLQVSRQSWEEINELWQRLQYQMMYWLWLLDSELPGDFGT-VGKWLAEAEKLLMDNDIPNAMNEETAAVISRKLEEHKLFFADLPRILAMFDNAKRSPVAQQIPLEQLRNMERRLQEVGPKAAERRIRLKFL 726 HSP 2 Score: 53.5286 bits (127), Expect = 7.324e-6 Identity = 84/374 (22.46%), Postives = 162/374 (43.32%), Query Frame = 2
Query: 11141 YNVLFNKCQNECDKCDHLIKLMTKYEISRADVLHWIEASTQTLLKCS---DYTLKQSQMKSKLLMIDNLEKELENYGQSKFVEAIQDGEELLGELAGMPMQ-IVQQQMADLKSDWMEISRQLNQLSSNLRNTTSRSEAFKEMSNRLSNWLDDIEHTGLMDLSHIEHQCEIPFESGNSSSKHDRAKTLLTELNRHKQDFLQLANLATELANPSFDIENSQIQNRYIRLSNNLKDKIEKLNKQQADYDQIKQDIEEMEKWVFQTSIRIINENA---EQGKTTNNTIQEIETLIKHSNEIIANILSQEPEIVKIGQAVDSLINISNNKNSDKEKELQDDLSKLIENFNNLKSSSIHKRDHLKDSVKKWDTYQDFLQS 12241
Y L Q K + + T++ + ++ WIE + Q L CS D + + KL +++L L GQ + +QD + Q +++ M ++ DW + + Q S+L+ +R F ++L WL++ E T ++ E E + +R KTL EL + QL + A +L D N ++Q+R +L N+ I L ++ DY+ Q ++++EKW+ Q S +++ N+ + T I++ E L+ + N+ ++ GQA I + ++ L + +++N+L +S+ ++ L +S+ K+ Y+D L S
Sbjct: 5834 YTKLLTSAQGLVAKIEKNLSDHTEFLNYKKEMDAWIEKAQQVLDDCSTDGDAAI----IAQKLDTVNSLASRLPE-GQ-HLLALVQDAYSKASNITPEDKQEKLRELMTKVREDWDALGLAVKQKLSDLKQAQNRWNDFAANKDKLEKWLNETETT-------LKVAPETKGELSEMKTLLERYKTLSNELKLKGNELEQLQSEARDLGT-EVDAVN-RLQSRCDKLKNDCSAHITALEQEMFDYNAYHQSLQDVEKWLLQISFQLMAHNSLFISNREQTQEQIKQHEALLVEIQKYQTNL----DDLNAKGQAQ---IKRYESSTPAIRPTVESQLKNIQDSYNSLLQTSVQIKNRLLESLAKFQEYEDTLDS 6185
BLAST of Nesprin-1 vs. Ensembl Fly
Match: Msp300 (gene:FBgn0261836 transcript:FBtr0303389) HSP 1 Score: 252.677 bits (644), Expect = 5.644e-66 Identity = 176/469 (37.53%), Postives = 268/469 (57.14%), Query Frame = 2
Query: 185 LKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAX---XXXXXXXXXXXXXXALG--------MANDPNAKVKGQ-----AKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNELDIVKDFNDKVDKNFENLNSKNNYDIFADLMSQRDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLME-PFPNVHDKTFNDKVLQKLKEHESIFNKKNDVLAKFREVLQNPPANISP-KQLEAMKTRMENVCKAEGPVREKLNIF 1537
L++EQE++QKKTFT W+NSYL ++ PP+ I DL+ DL DG L+ LLE+L+ L EK + +++ H LSN TAL+F+ + K+IKLVNINP+D+VDG+P +VLGL+WT I + E+L +G + N + +K + A+K L+ W NAL G+ +KDFG SW DG AF AL+ I LVN+ E++K +N++RLE AF++AE++LGI KLLD+EDVDV KPDEKSIMTYVAQFL YPE K + E + +V+ E + + + E L +++ D ++ + +K L++ S +L + ++ + + + ++ W W LD LPG G+ +G WL +AE+ LM+ PN ++ + +KL+EH+ F +LA F ++P A P +QL M+ R++ V R +L
Sbjct: 265 LQEEQERVQKKTFTNWINSYLLKRVPPLRIDDLINDLRDGTKLIALLEVLSGERLPVEKGRVLRRPHFLSNANTALQFLAS-KRIKLVNINPADLVDGRPPVVLGLIWTIILYFQIEENSRNLEYLGHGIGGSVSSLDSVGNQKHGDLKAEKWKQGARKTLLNWVTNALPKDSGVEVKDFGASWRDGVAFLALIDAIKANLVNLAELKKTSNRQRLETAFDVAESKLGIAKLLDAEDVDVPKPDEKSIMTYVAQFLHKYPEPKGASRDQSHVQQEADELRRFLVEKTTEYEPMVMMSSFPRDFGEYLLARSEVDAH---LAAYNRLKQLIESQS--GFLQVSRQSWEEINELWQRLQYQMMYWLWLLDSELPGDFGT-VGKWLAEAEKLLMDNDIPNAMNEETAAVISRKLEEHKLFFADLPRILAMFDNAKRSPVAQQIPLEQLRNMERRLQEVGPKAAERRIRLKFL 726 HSP 2 Score: 53.5286 bits (127), Expect = 7.700e-6 Identity = 84/374 (22.46%), Postives = 162/374 (43.32%), Query Frame = 2
Query: 11141 YNVLFNKCQNECDKCDHLIKLMTKYEISRADVLHWIEASTQTLLKCS---DYTLKQSQMKSKLLMIDNLEKELENYGQSKFVEAIQDGEELLGELAGMPMQ-IVQQQMADLKSDWMEISRQLNQLSSNLRNTTSRSEAFKEMSNRLSNWLDDIEHTGLMDLSHIEHQCEIPFESGNSSSKHDRAKTLLTELNRHKQDFLQLANLATELANPSFDIENSQIQNRYIRLSNNLKDKIEKLNKQQADYDQIKQDIEEMEKWVFQTSIRIINENA---EQGKTTNNTIQEIETLIKHSNEIIANILSQEPEIVKIGQAVDSLINISNNKNSDKEKELQDDLSKLIENFNNLKSSSIHKRDHLKDSVKKWDTYQDFLQS 12241
Y L Q K + + T++ + ++ WIE + Q L CS D + + KL +++L L GQ + +QD + Q +++ M ++ DW + + Q S+L+ +R F ++L WL++ E T ++ E E + +R KTL EL + QL + A +L D N ++Q+R +L N+ I L ++ DY+ Q ++++EKW+ Q S +++ N+ + T I++ E L+ + N+ ++ GQA I + ++ L + +++N+L +S+ ++ L +S+ K+ Y+D L S
Sbjct: 5834 YTKLLTSAQGLVAKIEKNLSDHTEFLNYKKEMDAWIEKAQQVLDDCSTDGDAAI----IAQKLDTVNSLASRLPE-GQ-HLLALVQDAYSKASNITPEDKQEKLRELMTKVREDWDALGLAVKQKLSDLKQAQNRWNDFAANKDKLEKWLNETETT-------LKVAPETKGELSEMKTLLERYKTLSNELKLKGNELEQLQSEARDLGT-EVDAVN-RLQSRCDKLKNDCSAHITALEQEMFDYNAYHQSLQDVEKWLLQISFQLMAHNSLFISNREQTQEQIKQHEALLVEIQKYQTNL----DDLNAKGQAQ---IKRYESSTPAIRPTVESQLKNIQDSYNSLLQTSVQIKNRLLESLAKFQEYEDTLDS 6185
BLAST of Nesprin-1 vs. Ensembl Fly
Match: Msp300 (gene:FBgn0261836 transcript:FBtr0303383) HSP 1 Score: 252.677 bits (644), Expect = 6.044e-66 Identity = 175/468 (37.39%), Postives = 267/468 (57.05%), Query Frame = 2
Query: 188 KDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAX---XXXXXXXXXXXXXXALG--------MANDPNAKVKGQ-----AKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNELDIVKDFNDKVDKNFENLNSKNNYDIFADLMSQRDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLME-PFPNVHDKTFNDKVLQKLKEHESIFNKKNDVLAKFREVLQNPPANISP-KQLEAMKTRMENVCKAEGPVREKLNIF 1537
++EQE++QKKTFT W+NSYL ++ PP+ I DL+ DL DG L+ LLE+L+ L EK + +++ H LSN TAL+F+ + K+IKLVNINP+D+VDG+P +VLGL+WT I + E+L +G + N + +K + A+K L+ W NAL G+ +KDFG SW DG AF AL+ I LVN+ E++K +N++RLE AF++AE++LGI KLLD+EDVDV KPDEKSIMTYVAQFL YPE K + E + +V+ E + + + E L +++ D ++ + +K L++ S +L + ++ + + + ++ W W LD LPG G+ +G WL +AE+ LM+ PN ++ + +KL+EH+ F +LA F ++P A P +QL M+ R++ V R +L
Sbjct: 625 REEQERVQKKTFTNWINSYLLKRVPPLRIDDLINDLRDGTKLIALLEVLSGERLPVEKGRVLRRPHFLSNANTALQFLAS-KRIKLVNINPADLVDGRPPVVLGLIWTIILYFQIEENSRNLEYLGHGIGGSVSSLDSVGNQKHGDLKAEKWKQGARKTLLNWVTNALPKDSGVEVKDFGASWRDGVAFLALIDAIKANLVNLAELKKTSNRQRLETAFDVAESKLGIAKLLDAEDVDVPKPDEKSIMTYVAQFLHKYPEPKGASRDQSHVQQEADELRRFLVEKTTEYEPMVMMSSFPRDFGEYLLARSEVDAH---LAAYNRLKQLIESQS--GFLQVSRQSWEEINELWQRLQYQMMYWLWLLDSELPGDFGT-VGKWLAEAEKLLMDNDIPNAMNEETAAVISRKLEEHKLFFADLPRILAMFDNAKRSPVAQQIPLEQLRNMERRLQEVGPKAAERRIRLKFL 1085 HSP 2 Score: 54.299 bits (129), Expect = 3.880e-6 Identity = 84/374 (22.46%), Postives = 162/374 (43.32%), Query Frame = 2
Query: 11141 YNVLFNKCQNECDKCDHLIKLMTKYEISRADVLHWIEASTQTLLKCS---DYTLKQSQMKSKLLMIDNLEKELENYGQSKFVEAIQDGEELLGELAGMPMQ-IVQQQMADLKSDWMEISRQLNQLSSNLRNTTSRSEAFKEMSNRLSNWLDDIEHTGLMDLSHIEHQCEIPFESGNSSSKHDRAKTLLTELNRHKQDFLQLANLATELANPSFDIENSQIQNRYIRLSNNLKDKIEKLNKQQADYDQIKQDIEEMEKWVFQTSIRIINENA---EQGKTTNNTIQEIETLIKHSNEIIANILSQEPEIVKIGQAVDSLINISNNKNSDKEKELQDDLSKLIENFNNLKSSSIHKRDHLKDSVKKWDTYQDFLQS 12241
Y L Q K + + T++ + ++ WIE + Q L CS D + + KL +++L L GQ + +QD + Q +++ M ++ DW + + Q S+L+ +R F ++L WL++ E T ++ E E + +R KTL EL + QL + A +L D N ++Q+R +L N+ I L ++ DY+ Q ++++EKW+ Q S +++ N+ + T I++ E L+ + N+ ++ GQA I + ++ L + +++N+L +S+ ++ L +S+ K+ Y+D L S
Sbjct: 6193 YTKLLTSAQGLVAKIEKNLSDHTEFLNYKKEMDAWIEKAQQVLDDCSTDGDAAI----IAQKLDTVNSLASRLPE-GQH-LLALVQDAYSKASNITPEDKQEKLRELMTKVREDWDALGLAVKQKLSDLKQAQNRWNDFAANKDKLEKWLNETETT-------LKVAPETKGELSEMKTLLERYKTLSNELKLKGNELEQLQSEARDLGT-EVDAVN-RLQSRCDKLKNDCSAHITALEQEMFDYNAYHQSLQDVEKWLLQISFQLMAHNSLFISNREQTQEQIKQHEALLVEIQKYQTNL----DDLNAKGQAQ---IKRYESSTPAIRPTVESQLKNIQDSYNSLLQTSVQIKNRLLESLAKFQEYEDTLDS 6544
BLAST of Nesprin-1 vs. Ensembl Fly
Match: Msp300 (gene:FBgn0261836 transcript:FBtr0303385) HSP 1 Score: 252.292 bits (643), Expect = 8.820e-66 Identity = 175/468 (37.39%), Postives = 267/468 (57.05%), Query Frame = 2
Query: 188 KDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAX---XXXXXXXXXXXXXXALG--------MANDPNAKVKGQ-----AKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNELDIVKDFNDKVDKNFENLNSKNNYDIFADLMSQRDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLME-PFPNVHDKTFNDKVLQKLKEHESIFNKKNDVLAKFREVLQNPPANISP-KQLEAMKTRMENVCKAEGPVREKLNIF 1537
++EQE++QKKTFT W+NSYL ++ PP+ I DL+ DL DG L+ LLE+L+ L EK + +++ H LSN TAL+F+ + K+IKLVNINP+D+VDG+P +VLGL+WT I + E+L +G + N + +K + A+K L+ W NAL G+ +KDFG SW DG AF AL+ I LVN+ E++K +N++RLE AF++AE++LGI KLLD+EDVDV KPDEKSIMTYVAQFL YPE K + E + +V+ E + + + E L +++ D ++ + +K L++ S +L + ++ + + + ++ W W LD LPG G+ +G WL +AE+ LM+ PN ++ + +KL+EH+ F +LA F ++P A P +QL M+ R++ V R +L
Sbjct: 625 REEQERVQKKTFTNWINSYLLKRVPPLRIDDLINDLRDGTKLIALLEVLSGERLPVEKGRVLRRPHFLSNANTALQFLAS-KRIKLVNINPADLVDGRPPVVLGLIWTIILYFQIEENSRNLEYLGHGIGGSVSSLDSVGNQKHGDLKAEKWKQGARKTLLNWVTNALPKDSGVEVKDFGASWRDGVAFLALIDAIKANLVNLAELKKTSNRQRLETAFDVAESKLGIAKLLDAEDVDVPKPDEKSIMTYVAQFLHKYPEPKGASRDQSHVQQEADELRRFLVEKTTEYEPMVMMSSFPRDFGEYLLARSEVDAH---LAAYNRLKQLIESQS--GFLQVSRQSWEEINELWQRLQYQMMYWLWLLDSELPGDFGT-VGKWLAEAEKLLMDNDIPNAMNEETAAVISRKLEEHKLFFADLPRILAMFDNAKRSPVAQQIPLEQLRNMERRLQEVGPKAAERRIRLKFL 1085 HSP 2 Score: 53.5286 bits (127), Expect = 6.796e-6 Identity = 109/487 (22.38%), Postives = 207/487 (42.51%), Query Frame = 2
Query: 10802 AENELETLKANWSKLSKRINELNNLKMDLDKALEHFNIWLNNSCKWFVNITETRKKVFESNETLQMKNNLQALKDDITEHKVDLSRLQTFVDSLMKICNDETFQKTLDEITKEYNVLFNKCQNECDKCDHLIKLMTKYEISRADVLHWIEASTQTLLKCS---DYTLKQSQMKSKLLMIDNLEKELENYGQSKFVEAIQDGEELLGELAGMPMQ-IVQQQMADLKSDWMEISRQLNQLSSNLRNTTSRSEAFKEMSNRLSNWLDDIEHTGLMDLSHIEHQCEIPFESGNSSSKHDRAKTLLTELNRHKQDFLQLANLATELANPSFDIENSQIQNRYIRLSNNLKDKIEKLNKQQADYDQIKQDIEEMEKWVFQTSIRIINENA---EQGKTTNNTIQEIETLIKHSNEIIANILSQEPEIVKIGQAVDSLINISNNKNSDKEKELQDDLSKLIENFNNLKSSSIHKRDHLKDSVKKWDTYQDFLQS 12241
A + LE+ A W ++ N++N ++K + N + + VN KK+ E E L K+N++ L D+ +L Q+ + D+T E Y L Q K + + T++ + ++ WIE + Q L CS D + + KL +++L L GQ + +QD + Q +++ M ++ DW + + Q S+L+ +R F ++L WL++ E T ++ E E + +R KTL EL + QL + A +L D N ++Q+R +L N+ I L ++ DY+ Q ++++EKW+ Q S +++ N+ + T I++ E L+ + N+ ++ GQA I + ++ L + +++N+L +S+ ++ L +S+ K+ Y+D L S
Sbjct: 6100 ARSSLESCLAAWQTFLQKFNKINLWIETMNKRVTKSQEGENKTPEDLVNA----KKLLE--EVLAEKDNVEDLNDN-----CELLMEQSACTRI----RDQTI-----ETQANYTKLLTSAQGLVAKIEKNLSDHTEFLNYKKEMDAWIEKAQQVLDDCSTDGDAAI----IAQKLDTVNSLASRLPE-GQ-HLLALVQDAYSKASNITPEDKQEKLRELMTKVREDWDALGLAVKQKLSDLKQAQNRWNDFAANKDKLEKWLNETETT-------LKVAPETKGELSEMKTLLERYKTLSNELKLKGNELEQLQSEARDLGT-EVDAVN-RLQSRCDKLKNDCSAHITALEQEMFDYNAYHQSLQDVEKWLLQISFQLMAHNSLFISNREQTQEQIKQHEALLVEIQKYQTNL----DDLNAKGQA---QIKRYESSTPAIRPTVESQLKNIQDSYNSLLQTSVQIKNRLLESLAKFQEYEDTLDS 6544
BLAST of Nesprin-1 vs. Ensembl Zebrafish
Match: syne1b (spectrin repeat containing, nuclear envelope 1b [Source:ZFIN;Acc:ZDB-GENE-071218-4]) HSP 1 Score: 263.462 bits (672), Expect = 4.436e-69 Identity = 179/470 (38.09%), Postives = 268/470 (57.02%), Query Frame = 2
Query: 185 LKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWT---------------AXXXXXXXXXXXXXXXALGMANDPN-----AKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYP-------EGKKPENISEEITAEINSGLMSMVQPPNELDIVKDFNDKVDKNFENLNSKNNYDIFADLMSQ----RDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLME--PFPNVHDKTFNDKVLQKLKEHESIFNKKNDVLAKFREVLQNPPAN---ISPKQLEAMKTRM 1486
L+DEQE +QK+TFTKW+NS+L + KPP + DL +D+ DG+ LL LLE+L+ L E+ + +++IH +SNI TAL+F+E +KIKLVNIN +D+ DG+P+IVLGL+WT A+ + + + P K +G AK+ L+ W N + + G+ +KDFG SW G AF++++H I P LV+M+ + K +N+E LE AF++AENELGIP+LLD EDVDV+KPDEKSIMTYVAQFLK YP +G++ E ++ E+ L + E D++ + + E+L K Y F Q + ++ LL + D L +D V+Q +D ++L +W LDK LPG LG IG+WL AE SL E P H++T N + +KL++H+ + F+++ ++ N + P+QL+ M R
Sbjct: 21 LQDEQESVQKRTFTKWINSHLAKHKPPFEVNDLFEDIKDGVKLLALLEVLSGQRLPCEQGRQLKRIHWVSNIGTALKFLEG-RKIKLVNINATDIADGRPSIVLGLMWTIILYFQIEELTSNLPALQALSSSASSVDSMASSETGSPPMKRKVVTKFQGNAKRALLRWVQNTATKRLGIEVKDFGASWRSGVAFHSVIHAIRPELVDMDVVRKRSNRENLEEAFSVAENELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDPHQSETDGQQEEREERKVLREVKIWLDQL-----ERDVL-----RAQGSEESLTDK--YQAFKSFRVQYEMRKKQIESLLQPVHRDGKLSVDQAVVKQ---SWDHVSVRLLDWHIHLDKSLPGPLGV-IGAWLHRAELSLREDVPIQQAHEETAN-IIHRKLEQHKEVLKNLEGHRQTFQQIHRDRSVNGVPVPPEQLQDMAERF 472 HSP 2 Score: 65.0846 bits (157), Expect = 3.566e-9 Identity = 104/477 (21.80%), Postives = 207/477 (43.40%), Query Frame = 2
Query: 10862 ELNNLKMDLDKALEHFNIWLNNSCKWFVNITETRKKVFESNETLQ----MKNNLQALKDDITEHKVDLSRLQTFVDSLMKICNDETFQ-KTLDEITKEYNVLFNKCQNECDKCDHLIKLMTKYEISRADVLHWIEASTQTLLKCSDYTLKQSQMKSKLLMIDNLEKELENYGQSKFVEAIQDGEELLGELAGMPMQIVQQQMADLKSDWMEISRQLNQLSSNLRNTTSRSEAFKEMSNRLSNWLDDIEH------TGLMDLSHIEHQCEIPFESGNSSSKHDRAKTLLTELNRHKQDFLQLANLATEL-----ANPSFDIENSQIQNRYIRLSNNLKDKIEKLNKQQADYDQIKQDIEEMEKWVFQTSIRI---INENAEQGKTTNNTIQEIETLI--KHSNEIIANILSQEPEIVKIGQAVDSLINISNNKNSDKEKELQDDLSKLIENFNNLKSSSIHKRDHLKDSVKKWDTYQD 12229
E N+L L++ L+ F+ L +W + + + +++ E +Q K+ L+AL++ E D L+ ++ L + D Q + + + KEYN L + EC + L++ ++ + D W+ + KC D ++ S L I + E GQ K GE L+ A ++ V+ ++ + DW + L+Q + L+N ++ F+ L +WL+D E + L DL+ + + R ++LL EL + L+L A +L A F SQ+ +Y+ LSN K+K ++ + +++ Q ++E++ WV TS + A++ + I+ +E L+ + EI +L E ++ N ++D ++ + L ++++ L S+SI + L+ ++ +W +YQ+
Sbjct: 2937 EFNSLAAQLEQDLQEFSSKLQ---EWRIKLQQV-EEMSAGEEAVQGWQIAKDTLEALQN--VEPMSD--NLKCQLNDLCRFSRDLGAQSERVSALIKEYNSLSLQASRECQGKEKLLE--QRFRAAFRDFQQWLVNAKINTAKCFDVPQNLAEASSSLQKIQEFLSDREQ-GQGKLNTVAASGELLMSIAAKDRVESVRAKINSAREDWKTLMTNLHQRENALQNLQAQMRDFETSVEPLQDWLNDTEEAVQESSSRLQDLTAKKQELH-------------RLQSLLEELASKEPQLLRLREKAQQLWDGHTAGKGFVHRVSQLSAQYLALSNLTKEKASRIERVVSEHQLFSQGLKELQNWVSDTSHMLQTYCTPTADKNVLDSRMIK-LEALLTARQEKEIQLKMLLTRGE------------SVQRNTSADGVPLVRQQIEDLKDSWDGLLSASIQCKSQLEGALSQWTSYQE 3376
BLAST of Nesprin-1 vs. Ensembl Zebrafish
Match: syne1b (spectrin repeat containing, nuclear envelope 1b [Source:ZFIN;Acc:ZDB-GENE-071218-4]) HSP 1 Score: 263.462 bits (672), Expect = 4.436e-69 Identity = 179/470 (38.09%), Postives = 268/470 (57.02%), Query Frame = 2
Query: 185 LKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWT---------------AXXXXXXXXXXXXXXXALGMANDPN-----AKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYP-------EGKKPENISEEITAEINSGLMSMVQPPNELDIVKDFNDKVDKNFENLNSKNNYDIFADLMSQ----RDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLME--PFPNVHDKTFNDKVLQKLKEHESIFNKKNDVLAKFREVLQNPPAN---ISPKQLEAMKTRM 1486
L+DEQE +QK+TFTKW+NS+L + KPP + DL +D+ DG+ LL LLE+L+ L E+ + +++IH +SNI TAL+F+E +KIKLVNIN +D+ DG+P+IVLGL+WT A+ + + + P K +G AK+ L+ W N + + G+ +KDFG SW G AF++++H I P LV+M+ + K +N+E LE AF++AENELGIP+LLD EDVDV+KPDEKSIMTYVAQFLK YP +G++ E ++ E+ L + E D++ + + E+L K Y F Q + ++ LL + D L +D V+Q +D ++L +W LDK LPG LG IG+WL AE SL E P H++T N + +KL++H+ + F+++ ++ N + P+QL+ M R
Sbjct: 21 LQDEQESVQKRTFTKWINSHLAKHKPPFEVNDLFEDIKDGVKLLALLEVLSGQRLPCEQGRQLKRIHWVSNIGTALKFLEG-RKIKLVNINATDIADGRPSIVLGLMWTIILYFQIEELTSNLPALQALSSSASSVDSMASSETGSPPMKRKVVTKFQGNAKRALLRWVQNTATKRLGIEVKDFGASWRSGVAFHSVIHAIRPELVDMDVVRKRSNRENLEEAFSVAENELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDPHQSETDGQQEEREERKVLREVKIWLDQL-----ERDVL-----RAQGSEESLTDK--YQAFKSFRVQYEMRKKQIESLLQPVHRDGKLSVDQAVVKQ---SWDHVSVRLLDWHIHLDKSLPGPLGV-IGAWLHRAELSLREDVPIQQAHEETAN-IIHRKLEQHKEVLKNLEGHRQTFQQIHRDRSVNGVPVPPEQLQDMAERF 472 HSP 2 Score: 65.0846 bits (157), Expect = 3.566e-9 Identity = 104/477 (21.80%), Postives = 207/477 (43.40%), Query Frame = 2
Query: 10862 ELNNLKMDLDKALEHFNIWLNNSCKWFVNITETRKKVFESNETLQ----MKNNLQALKDDITEHKVDLSRLQTFVDSLMKICNDETFQ-KTLDEITKEYNVLFNKCQNECDKCDHLIKLMTKYEISRADVLHWIEASTQTLLKCSDYTLKQSQMKSKLLMIDNLEKELENYGQSKFVEAIQDGEELLGELAGMPMQIVQQQMADLKSDWMEISRQLNQLSSNLRNTTSRSEAFKEMSNRLSNWLDDIEH------TGLMDLSHIEHQCEIPFESGNSSSKHDRAKTLLTELNRHKQDFLQLANLATEL-----ANPSFDIENSQIQNRYIRLSNNLKDKIEKLNKQQADYDQIKQDIEEMEKWVFQTSIRI---INENAEQGKTTNNTIQEIETLI--KHSNEIIANILSQEPEIVKIGQAVDSLINISNNKNSDKEKELQDDLSKLIENFNNLKSSSIHKRDHLKDSVKKWDTYQD 12229
E N+L L++ L+ F+ L +W + + + +++ E +Q K+ L+AL++ E D L+ ++ L + D Q + + + KEYN L + EC + L++ ++ + D W+ + KC D ++ S L I + E GQ K GE L+ A ++ V+ ++ + DW + L+Q + L+N ++ F+ L +WL+D E + L DL+ + + R ++LL EL + L+L A +L A F SQ+ +Y+ LSN K+K ++ + +++ Q ++E++ WV TS + A++ + I+ +E L+ + EI +L E ++ N ++D ++ + L ++++ L S+SI + L+ ++ +W +YQ+
Sbjct: 2937 EFNSLAAQLEQDLQEFSSKLQ---EWRIKLQQV-EEMSAGEEAVQGWQIAKDTLEALQN--VEPMSD--NLKCQLNDLCRFSRDLGAQSERVSALIKEYNSLSLQASRECQGKEKLLE--QRFRAAFRDFQQWLVNAKINTAKCFDVPQNLAEASSSLQKIQEFLSDREQ-GQGKLNTVAASGELLMSIAAKDRVESVRAKINSAREDWKTLMTNLHQRENALQNLQAQMRDFETSVEPLQDWLNDTEEAVQESSSRLQDLTAKKQELH-------------RLQSLLEELASKEPQLLRLREKAQQLWDGHTAGKGFVHRVSQLSAQYLALSNLTKEKASRIERVVSEHQLFSQGLKELQNWVSDTSHMLQTYCTPTADKNVLDSRMIK-LEALLTARQEKEIQLKMLLTRGE------------SVQRNTSADGVPLVRQQIEDLKDSWDGLLSASIQCKSQLEGALSQWTSYQE 3376
BLAST of Nesprin-1 vs. Ensembl Zebrafish
Match: syne1a (spectrin repeat containing, nuclear envelope 1a [Source:ZFIN;Acc:ZDB-GENE-030131-4172]) HSP 1 Score: 234.187 bits (596), Expect = 2.836e-60 Identity = 170/479 (35.49%), Postives = 259/479 (54.07%), Query Frame = 2
Query: 185 LKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDK------KIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXXXXXALG---------------------MANDPNAKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNELDIVKDFNDKVDKNFENLNSKNNYDIF----ADLMSQRDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLMEPF--PNVHDKTFNDKVLQKLKEHESIFNKKNDVLAKFREVLQ---------NPPANISPKQLEAMKTRMENV 1495
L+DEQE +QK+TFTKW+NS+L ++ PP+++ DL +D+ DG++LL LLE+L+ L E+ + +++IH ++N+ AL+F+E + IKLVNIN +DVVDG+P+IVLGL+WT I+ + E+ L AL + P +G AK+ L+ W N + + GL++KDFG SW G AF+A++ + P LVNME + + N+E LE AF++AE ELGIP+LLD EDVDV+KPDEKSIMTYVAQFLK +P+ + E ++ E L + ++++ D + + Y F QR ++ + D L D V+Q +++ +L +W LD LP LG E+G WL AEE L E HD+T ++L++ E + +L + ++ LQ N P I +QL+ M R+ +
Sbjct: 34 LRDEQEAVQKRTFTKWINSHLAKRNPPLVVSDLFEDVKDGVMLLALLEVLSGHKLPCEQGRKLRRIHWVANVGRALKFLEGRRVRQSIPTIKLVNINTTDVVDGRPSIVLGLIWT-IILYFQIEELTSHLPALQPQSSSNSSVESSNSTETSSPPVKRKPRLSFQGGAKRALLKWVQNTATKRMGLDVKDFGPSWRTGVAFHAVIFALRPHLVNMERVWRRGNRENLEEAFSLAERELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHHPDRQHTETGQQQEEKEQRKTLRELKAWADQME-----RDCAQAQRDGGSLTVRYQTFKRFRVQFEVQRRQVETCVQSTQKDGKLTADQALVKQA---WERLCKRLLDWHLQLDSSLPHPLG-EVGVWLHQAEEILREELIPQQAHDETAKAIHKKRLRDQEIL-----RLLERHKQTLQLIHRDRCVNNMP--IPTEQLQDMAERLHYI 495 HSP 2 Score: 58.151 bits (139), Expect = 4.484e-7 Identity = 85/428 (19.86%), Postives = 181/428 (42.29%), Query Frame = 2
Query: 10964 KKVFESNETLQ-MKNNLQALKDDITEHKVDLSRLQTFVDSLMKICNDETFQKTLDEITKEYNVLFNKCQNECDKCDHLIKLMTKYEISRADVLHWIEASTQTLLKCSDYTLKQSQMKSKLLMIDNLEKELENYGQSKFVEAIQDGEELLGELAGMPMQIVQQQMADLKSDWMEISRQLNQLSSNLRNTTSRSEAFKEMSNRLSNWLDDIEHTGLMDLSHIEHQCEIPFESGNSSSKHDRAKTLLTELNRHKQDFLQLANLATEL-----ANPSFDIENSQIQNRYIRLSNNLKDKIEKLNKQQADYDQIKQDIEEMEKWVFQTSIRIINENAEQGKTTNNTIQEIETLIKHSNEIIANILSQEPEIVKIGQAVDSLINISNNKNSDKEKELQDDLSKLIENFNNLKSSSIHKRDHLKDSVKKWDTYQD 12229
K V E +T + M+ L+A +++ DL V +L+K+ +N L + EC + L++ ++ S D W+ + + KC D L I + E GQ++ + GE+L LA ++ ++ + K DW + L + + L+ S+ + F+ L +WL+ E + + S H ++P + S + +TLL E+ + + L A L A SF Q+ Y+ LSN +K+K+ ++ + ++ Q ++E++ WV +E+ + KT + LI ++ A + + + + +++ + ++ N +++ ++ + L +++ +L S+SI + L+ ++ W +YQ+
Sbjct: 2910 KGVLEGLQTAEVMEEKLKAQLNELCGFSSDLGPQSDRVSALIKL----------------HNSLSLRASRECQNKEKLLE--QRFRSSLHDFRQWLVNANISTAKCFDSPHSIQDASIALQRIQEFMSDKEQ-GQTRLSAVLTYGEQLSSVLAAERVEAIRTKANTAKDDWKSLMDSLQRRETALQVLQSQMQDFEASIEPLQDWLNRTE-ISVQESSARLH--DLPAKRLELS----KLQTLLEEMRSRESELAGLRGRAHGLWDGQGAGKSFVHRVCQLAACYLALSNLIKEKVSRVERVVGEHQLFSQGLQELQNWV--------SESQQVLKTCRCPTSDKTVLITRMGQLEALLAACQGKEIQLKMLITRGESVQRNTSAEGVPVVRKQIQDLKDSWESLLSTSIQCKSQLEGALSHWTSYQE 3303
BLAST of Nesprin-1 vs. Ensembl Zebrafish
Match: syne1a (spectrin repeat containing, nuclear envelope 1a [Source:ZFIN;Acc:ZDB-GENE-030131-4172]) HSP 1 Score: 233.417 bits (594), Expect = 5.361e-60 Identity = 170/479 (35.49%), Postives = 259/479 (54.07%), Query Frame = 2
Query: 185 LKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDK------KIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXXXXXALG---------------------MANDPNAKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNELDIVKDFNDKVDKNFENLNSKNNYDIF----ADLMSQRDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLMEPF--PNVHDKTFNDKVLQKLKEHESIFNKKNDVLAKFREVLQ---------NPPANISPKQLEAMKTRMENV 1495
L+DEQE +QK+TFTKW+NS+L ++ PP+++ DL +D+ DG++LL LLE+L+ L E+ + +++IH ++N+ AL+F+E + IKLVNIN +DVVDG+P+IVLGL+WT I+ + E+ L AL + P +G AK+ L+ W N + + GL++KDFG SW G AF+A++ + P LVNME + + N+E LE AF++AE ELGIP+LLD EDVDV+KPDEKSIMTYVAQFLK +P+ + E ++ E L + ++++ D + + Y F QR ++ + D L D V+Q +++ +L +W LD LP LG E+G WL AEE L E HD+T ++L++ E + +L + ++ LQ N P I +QL+ M R+ +
Sbjct: 34 LRDEQEAVQKRTFTKWINSHLAKRNPPLVVSDLFEDVKDGVMLLALLEVLSGHKLPCEQGRKLRRIHWVANVGRALKFLEGRRVRQSIPTIKLVNINTTDVVDGRPSIVLGLIWT-IILYFQIEELTSHLPALQPQSSSNSSVESSNSTETSSPPVKRKPRLSFQGGAKRALLKWVQNTATKRMGLDVKDFGPSWRTGVAFHAVIFALRPHLVNMERVWRRGNRENLEEAFSLAERELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHHPDRQHTETGQQQEEKEQRKTLRELKAWADQME-----RDCAQAQRDGGSLTVRYQTFKRFRVQFEVQRRQVETCVQSTQKDGKLTADQALVKQA---WERLCKRLLDWHLQLDSGLPHPLG-EVGVWLHQAEEILREELIPQQAHDETAKAIHKKRLRDQEIL-----RLLERHKQTLQLIHRDRCVNNMP--IPTEQLQDMAERLHYI 495 HSP 2 Score: 57.7658 bits (138), Expect = 4.677e-7 Identity = 94/485 (19.38%), Postives = 206/485 (42.47%), Query Frame = 2
Query: 10964 KKVFESNETLQ-MKNNLQALKDDITEHKVDLSRLQTFVDSLMKICNDETFQKTLDEITKEYNVLFNKCQNECDKCDHLIKLMTKYEISRADVLHWIEASTQTLLKCSDYTLKQSQMKSKLLMIDNLEKELENYGQSKFVEAIQDGEELLGELAGMPMQIVQQQMADLKSDWMEISRQLNQLSSNLRNTTSRSEAFKEMSNRLSNWLDDIEHTGLMDLSHIEHQCEIPFESGNSSSKHDRAKTLLTELNRHKQDFLQLANLATEL-----ANPSFDIENSQIQNRYIRLSNNLKDKIEKLNKQQADYDQIKQDIEEMEKWVFQTSIRIINENAEQGKTTNNTIQEIETLIKHSNEIIANILSQEPEIVKIGQAVDSLINISNNKNSDKEKELQDDLSKLIENFNNLKSSSIHKRDHLKDSVKKWDTYQDFLQSTKLFLDN---ELPNWWRERNQDQMKSAYSNFNNEPIL-KEILDMDNKLNGLKT 12388
K V E +T + M+ L+A +++ DL V +L+K+ +N L + EC + L++ ++ S D W+ + + KC D L I + E GQ++ + GE+L LA ++ ++ + K DW + L + + L+ S+ + F+ L +WL+ E + + S H ++P + S + +TLL E+ + + L A L A SF Q+ Y+ LSN +K+K+ ++ + ++ Q ++E++ WV +E+ + KT + LI ++ A + + + + +++ + ++ N +++ ++ + L +++ +L S+SI + L+ ++ W +YQ+ + + +++ L N +++ +M+ +N +L +E+L + L + T
Sbjct: 2910 KGVLEGLQTAEVMEEKLKAQLNELCGFSSDLGPQSDRVSALIKL----------------HNSLSLRASRECQNKEKLLE--QRFRSSLHDFRQWLVNANISTAKCFDSPHSIQDASIALQRIQEFMSDKEQ-GQTRLSAVLTYGEQLSSVLAAERVEAIRTKANTAKDDWKSLMDSLQRRETALQVLQSQMQDFEASIEPLQDWLNRTE-ISVQESSARLH--DLPAKRLELS----KLQTLLEEMRSRESELAGLRGRAHGLWDGQGAGKSFVHRVCQLAACYLALSNLIKEKVSRVERVVGEHQLFSQGLQELQNWV--------SESQQVLKTCRCPTSDKTVLITRMGQLEALLAACQGKEIQLKMLITRGESVQRNTSAEGVPVVRKQIQDLKDSWESLLSTSIQCKSQLEGALSHWTSYQEDVSQFECWMERVEESLGN--SDKHYAEMRDKTANLGRAKLLYEEVLSHSSPLETIAT 3358
BLAST of Nesprin-1 vs. Ensembl Zebrafish
Match: syne2b (spectrin repeat containing, nuclear envelope 2b [Source:ZFIN;Acc:ZDB-GENE-071218-5]) HSP 1 Score: 157.532 bits (397), Expect = 9.903e-42 Identity = 108/266 (40.60%), Postives = 149/266 (56.02%), Query Frame = 2
Query: 194 EQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWT--------------------------AXXXXXXXXXXXXXXXALGMANDPNAKVKGQAKKGLMAWTNNALSDKYG--LNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLK 907
EQE++QK+TFT W+N+ L ++ PP+ + DL + DG LLDLLE+++ + K++ Q SNI AL F++ K IKLVNIN SD++DGKP+I+LGLVWT A L + + +A+ + AKK L+ W + G LN+KDF SW G F A++H + P +V++ TN++ LE AF+IAE EL IP+LLD DVDV PDEKSIMTYVAQFL+
Sbjct: 2 EQEQIQKRTFTNWINAQLSKRSPPVTVVDLFNEFRDGSRLLDLLEVMSGQRIVKKRRGTFQH---RSNIEKALAFLKK-KSIKLVNINVSDIMDGKPSIILGLVWTIIMHIHIEELASTLSFSSRQSSLESLASLDTRSTNSSARSSPVPPRGSPLHARFRVSAKKALLLWVREQ-CQRAGCTLNVKDFKVSWRSGVVFLAILHALRPNIVDLTRARTRTNRQNLEEAFHIAERELHIPRLLDPADVDVRDPDEKSIMTYVAQFLQ 262
BLAST of Nesprin-1 vs. Ensembl Xenopus
Match: SYNE1 (spectrin repeat containing, nuclear envelope 1 [Source:NCBI gene;Acc:100145637]) HSP 1 Score: 238.81 bits (608), Expect = 1.537e-61 Identity = 207/631 (32.81%), Postives = 322/631 (51.03%), Query Frame = 2
Query: 152 RKDTVVKKGVLLKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDK-------KIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXXXXXALGM--------------ANDPNAK------VKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNM--EEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENIS-------------------EEITAEINSGLMSMVQPPNELDIVKDFNDKVDKNFENLNSKNNYDIFADLMSQRDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLMEPF--PNVHDKTFNDKVLQKLKEHESIFNKKNDVLAKFREVLQNPPANISP---KQLEAMKTRMENVCKAEGPVREKLNIFGIQANLKNKAQKWAVDLNSWDSPIQSKQDLLDKIEQFNISMENGTSMDKFTSQLDELVKRKVKFCKENPVLDEDLLNFINKAINECEEENDILPEKFESTLMKLENLSSEWDEISD 1885
+K T K DEQE +QK+TFTKW+NS+L ++ PP++I +L +D+ DG L+ LLE+L+ L E+ + +++IH ++NI AL+F+E + +IKLVNIN +D+ DG+P+IVLGL+WT IL+FQIEE L Q M A P K ++G AKK L+ W + + G+ +KDFG SW +G AF+++++ I P LV+M E++++ TN+E LE AF+IAENELGIP+LLD EDVDV+KPDEKSIMTY+AQFLK YP+ P + S E+ +I+ M P + K + + Y++ +R ++ L+ + D L LD V+Q ++K ++ +W LDK LP LG+ I SWL AE ++ E H++T N + +KL++H+ + F+E+ ++ N P +QLE M R V + KL ++ L L SW ++D ++ + Q I+ +G ++F Q E + +K E V + + K +NE + L + S LE + + WD+ S+
Sbjct: 18 QKKTFNKMFFFFSDEQEAVQKRTFTKWINSHLAKRHPPMVINELFEDIKDGTKLIALLEVLSGQKLPCEQGRQLKRIHWVANIGAALKFLEGRRVMTFLIFQIKLVNINSTDIADGRPSIVLGLIWTIILYFQIEELTSNLPQLHAMSSSTSSVDSVVSSEAASPPIKRKIVNKIQGSAKKALLRWVQYTAAKRLGIEVKDFGPSWRNGIAFHSVIYAIRPDLVDMDIEKLKRRTNRENLEEAFSIAENELGIPRLLDPEDVDVDKPDEKSIMTYIAQFLKHYPD---PHHTSLDGQEDKDRIVLRDMKVWLEQFEKDISRAQMVESSPQDRYQSFKQY-------------RVQYEV------KRKQVEALIHPLGKDGKLSLDQTMVKQA---WEKVSSRIFDWHLQLDKSLPAPLGT-IASWLYRAEVAMREEIVVQQSHEETAN-IMHRKLEQHK---------VTSFQEIHRSRSVNGIPVPIEQLEDMAERFSYVASSSHLHMIKLEFMELKYRLLALLVLAESKLKSWIIKY-GRRDSVELLLQNYIAFIDG---NRFFEQY-EFTSQSLKQAAEMYVKADGSAENVTKFLNETTVQWKNLSVEVRSVRSMLEEVITNWDKYSN 607 HSP 2 Score: 89.7373 bits (221), Expect = 1.654e-16 Identity = 118/512 (23.05%), Postives = 222/512 (43.36%), Query Frame = 2
Query: 10796 ETAENELETLKANWSKLSKRI------------------NELNNLKMDLDKALEHFNIWLNNSCKWFVNITE-----TRKKVFESNETLQMKNNLQALKDDITEHKVDLSRLQTFVDSLMKICND-ETFQKTLDEITKEYNVLFNKCQNECDKCDHLIKLMTKYEISRADVLHWIEASTQTLLKCSDYTLKQSQMKSKLLMIDNLEKELENYGQSKFVEAIQDGEELLGELAGMPMQIVQQQMADLKSDWMEISRQLNQLSSNLRNTTSRSEAFKEMSNRLSNWLDDIEHTGLMDLSHIEHQCEIPFESGNSSSKHDRAKTLLTELNRHKQDFLQLANLATEL-----ANPSFDIENSQIQNRYIRLSNNLKDKIEKLNKQQADYDQIKQDIEEMEKWVFQTSIRIINENAEQGK---TTNNTIQEIET--LIKHSNEIIANILSQEPEIVKIGQAVDSLINISNNKNSDKEKELQDDLSKLIENFNNLKSSSIHKRDHLKDSVKKWDTYQD 12229
E +NE+ +L+A+W + I E +N L+ A++ F+ +L KW + + T K++ E + + K+ L AL D EH D L+T ++ L + D + + + KEYN L + C + + L ++ + D W+ + T KC D S++ + L I E EN GQ K + GE L L ++ +Q+M K DW L+Q S L N + + F+ ++ + WL E + D ++ H ++P + + + +++L E++ H+ +L A +L A SF SQ+ +Y+ LS+ K+K+ ++++ A++ Q Q + E+E W+ + +I ++ ++ + ++E L+K EI N+L E ++ N + + +Q+ L L + +L S I + HL+ ++ KW +YQD
Sbjct: 1932 EQMDNEIHSLQADWKQWEDSICHSQKALDGLLNQMAISEQEFSNQVSKLEDAIQDFSFFLE---KWTQKLNQGEGKDTDKEIVE--QWHRQKDVLTALND--AEHVTD--ELKTKLNDLCRFSKDLSIYSAKVSSLIKEYNSLCLQASKGCQNKEQV--LQQRFRTAFRDFQQWLVNAKVTTAKCFDIPQSVSEVSANLQKIQECLSESEN-GQHKLQTVMTRGELLYSILTEEKAKVTRQKMLTAKDDWKGFISSLHQKESALENLQIQMKDFETSADPVQTWLSATEKI-VRDSNNRLH--DLP----SKKKEQQKLQSILEEISSHEPQITRLKEKAQQLREGQSACKSFAHRGSQLSAQYLALSSLTKEKMSRMDRIVAEHQQFSQGMIELEDWISE-AIHMLQSYCHPTADRSVLDSRMSKLEALLLVKQEKEIEMNMLLSRGE------------SVVRNTSPEGAPAIQNQLQDLKNTWASLLLSCIQCKSHLEGALSKWTSYQD 2411
BLAST of Nesprin-1 vs. Ensembl Xenopus
Match: SYNE1 (spectrin repeat containing, nuclear envelope 1 [Source:NCBI gene;Acc:100145637]) HSP 1 Score: 216.853 bits (551), Expect = 6.634e-55 Identity = 175/513 (34.11%), Postives = 278/513 (54.19%), Query Frame = 2
Query: 218 TFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXXXXXALGM--------------ANDPNAK------VKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNM--EEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENIS-----EEITAEINSGLMSMVQPPNELDIVKDFN---DKVDKNFENL-----NSKNNYDIFADLMSQ----RDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLMEPF--PNVHDKTFNDKVLQKLKEHESIFNKKNDVLAKFREVLQNPPANISP---KQLEAMKTRMENVCKAEGPVREKLNIFGIQANL-------KNKAQKWAVDLNSWDS 1603
T +++ S+L Q+ PP++I +L +D+ DG L+ LLE+L+ L E+ + +++IH ++NI AL+F+E ++IKLVNIN +D+ DG+P+IVLGL+WT IL+FQIEE L Q M A P K ++G AKK L+ W + + G+ +KDFG SW +G AF+++++ I P LV+M E++++ TN+E LE AF+IAENELGIP+LLD EDVDV+KPDEKSIMTY+AQFLK YP+ P + S + + A + + +++D ++ +K+ + ++ Y F Q R ++ L+ + D L LD V+Q ++K ++ +W LDK LP LG+ I SWL AE ++ E H++T N + +KL++H+ + + F+E+ ++ N P +QLE M R V + KL ++ L ++K + W + DS
Sbjct: 12 TLNQYVISFL-QRHPPMVINELFEDIKDGTKLIALLEVLSGQKLPCEQGRQLKRIHWVANIGAALKFLEG-RRIKLVNINSTDIADGRPSIVLGLIWTIILYFQIEELTSNLPQLHAMSSSTSSVDSVVSSEAASPPIKRKIVNKIQGSAKKALLRWVQYTAAKRLGIEVKDFGPSWRNGIAFHSVIYAIRPDLVDMDIEKLKRRTNRENLEEAFSIAENELGIPRLLDPEDVDVDKPDEKSIMTYIAQFLKHYPD---PHHTSLDGQEDSVMAGGTPSFSRSSKHREDRIVLRDMKVWLEQFEKDISRAQMVESSPQDRYQSFKQYRVQYEVKRKQVEALIHPLGKDGKLSLDQTMVKQA---WEKVSSRIFDWHLQLDKSLPAPLGT-IASWLYRAEVAMREEIVVQQSHEETAN-IMHRKLEQHKDVLKNLDGYKKAFQEIHRSRSVNGIPVPIEQLEDMAERFSYVASSSHLHMIKLEFMELKYRLLALLVLAESKLKSWIIKYGRRDS 514 HSP 2 Score: 75.0998 bits (183), Expect = 4.177e-12 Identity = 95/399 (23.81%), Postives = 175/399 (43.86%), Query Frame = 2
Query: 10796 ETAENELETLKANWSKLSKRI------------------NELNNLKMDLDKALEHFNIWLNNSCKWFVNITE-----TRKKVFESNETLQMKNNLQALKDDITEHKVDLSRLQTFVDSLMKICND-ETFQKTLDEITKEYNVLFNKCQNECDKCDHLIKLMTKYEISRADVLHWIEASTQTLLKCSDYTLKQSQMKSKLLMIDNLEKELENYGQSKFVEAIQDGEELLGELAGMPMQIVQQQMADLKSDWMEISRQLNQLSSNLRNTTSRSEAFKEMSNRLSNWLDDIEHTGLMDLSHIEHQCEIPFESGNSSSKHDRAKTLLTELNRHKQDFLQLANLATEL-----ANPSFDIENSQIQNRYIRLSNNLKDKIEKLNKQQADYDQIKQDIEEMEKWV 11905
E +NE+ +L+A+W + I E +N L+ A++ F+ +L KW + + T K++ E + + K+ L AL D EH D L+T ++ L + D + + + KEYN L + C + + L ++ + D W+ + T KC D S++ + L I E EN GQ K + GE L L ++ +Q+M K DW L+Q S L N + + F+ ++ + WL E + D ++ H ++P + + + +++L E++ H+ +L A +L A SF SQ+ +Y+ LS+ K+K+ ++++ A++ Q Q + E+E W+
Sbjct: 2847 EQMDNEIHSLQADWKQWEDSICHSQKALDGLLNQMAISEQEFSNQVSKLEDAIQDFSFFLE---KWTQKLNQGEGKDTDKEIVE--QWHRQKDVLTALND--AEHVTD--ELKTKLNDLCRFSKDLSIYSAKVSSLIKEYNSLCLQASKGCQNKEQV--LQQRFRTAFRDFQQWLVNAKVTTAKCFDIPQSVSEVSANLQKIQECLSESEN-GQHKLQTVMTRGELLYSILTEEKAKVTRQKMLTAKDDWKGFISSLHQKESALENLQIQMKDFETSADPVQTWLSATEKI-VRDSNNRLH--DLP----SKKKEQQKLQSILEEISSHEPQITRLKEKAQQLREGQSACKSFAHRGSQLSAQYLALSSLTKEKMSRMDRIVAEHQQFSQGMIELEDWI 3226
BLAST of Nesprin-1 vs. Ensembl Xenopus
Match: SYNE1 (spectrin repeat containing, nuclear envelope 1 [Source:NCBI gene;Acc:100145637]) HSP 1 Score: 216.853 bits (551), Expect = 7.033e-55 Identity = 175/508 (34.45%), Postives = 280/508 (55.12%), Query Frame = 2
Query: 218 TFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXXXXXALGM--------------ANDPNAK------VKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNM--EEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNELDIVKDFN---DKVDKNFENL-----NSKNNYDIFADLMSQ----RDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLMEPF--PNVHDKTFNDKVLQKLKEHESIFNKKNDVLAKFREVLQNPPANISP---KQLEAMKTRMENVCKAEGPVREKLNIFGIQANL-------KNKAQKWAVDLNSWDS 1603
T +++ S+L Q+ PP++I +L +D+ DG L+ LLE+L+ L E+ + +++IH ++NI AL+F+E ++IKLVNIN +D+ DG+P+IVLGL+WT IL+FQIEE L Q M A P K ++G AKK L+ W + + G+ +KDFG SW +G AF+++++ I P LV+M E++++ TN+E LE AF+IAENELGIP+LLD EDVDV+KPDEKSIMTY+AQFLK YP+ P + S + + +S ++ + +++D ++ +K+ + ++ Y F Q R ++ L+ + D L LD V+Q ++K ++ +W LDK LP LG+ I SWL AE ++ E H++T N + +KL++H+ + + F+E+ ++ N P +QLE M R V + KL ++ L ++K + W + DS
Sbjct: 29 TLNQYVISFL-QRHPPMVINELFEDIKDGTKLIALLEVLSGQKLPCEQGRQLKRIHWVANIGAALKFLEG-RRIKLVNINSTDIADGRPSIVLGLIWTIILYFQIEELTSNLPQLHAMSSSTSSVDSVVSSEAASPPIKRKIVNKIQGSAKKALLRWVQYTAAKRLGIEVKDFGPSWRNGIAFHSVIYAIRPDLVDMDIEKLKRRTNRENLEEAFSIAENELGIPRLLDPEDVDVDKPDEKSIMTYIAQFLKHYPD---PHHTS--LDGQEDSVSIAKEYFREDRIVLRDMKVWLEQFEKDISRAQMVESSPQDRYQSFKQYRVQYEVKRKQVEALIHPLGKDGKLSLDQTMVKQA---WEKVSSRIFDWHLQLDKSLPAPLGT-IASWLYRAEVAMREEIVVQQSHEETAN-IMHRKLEQHKDVLKNLDGYKKAFQEIHRSRSVNGIPVPIEQLEDMAERFSYVASSSHLHMIKLEFMELKYRLLALLVLAESKLKSWIIKYGRRDS 524 HSP 2 Score: 90.1225 bits (222), Expect = 1.299e-16 Identity = 118/512 (23.05%), Postives = 222/512 (43.36%), Query Frame = 2
Query: 10796 ETAENELETLKANWSKLSKRI------------------NELNNLKMDLDKALEHFNIWLNNSCKWFVNITE-----TRKKVFESNETLQMKNNLQALKDDITEHKVDLSRLQTFVDSLMKICND-ETFQKTLDEITKEYNVLFNKCQNECDKCDHLIKLMTKYEISRADVLHWIEASTQTLLKCSDYTLKQSQMKSKLLMIDNLEKELENYGQSKFVEAIQDGEELLGELAGMPMQIVQQQMADLKSDWMEISRQLNQLSSNLRNTTSRSEAFKEMSNRLSNWLDDIEHTGLMDLSHIEHQCEIPFESGNSSSKHDRAKTLLTELNRHKQDFLQLANLATEL-----ANPSFDIENSQIQNRYIRLSNNLKDKIEKLNKQQADYDQIKQDIEEMEKWVFQTSIRIINENAEQGK---TTNNTIQEIET--LIKHSNEIIANILSQEPEIVKIGQAVDSLINISNNKNSDKEKELQDDLSKLIENFNNLKSSSIHKRDHLKDSVKKWDTYQD 12229
E +NE+ +L+A+W + I E +N L+ A++ F+ +L KW + + T K++ E + + K+ L AL D EH D L+T ++ L + D + + + KEYN L + C + + L ++ + D W+ + T KC D S++ + L I E EN GQ K + GE L L ++ +Q+M K DW L+Q S L N + + F+ ++ + WL E + D ++ H ++P + + + +++L E++ H+ +L A +L A SF SQ+ +Y+ LS+ K+K+ ++++ A++ Q Q + E+E W+ + +I ++ ++ + ++E L+K EI N+L E ++ N + + +Q+ L L + +L S I + HL+ ++ KW +YQD
Sbjct: 2840 EQMDNEIHSLQADWKQWEDSICHSQKALDGLLNQMAISEQEFSNQVSKLEDAIQDFSFFLE---KWTQKLNQGEGKDTDKEIVE--QWHRQKDVLTALND--AEHVTD--ELKTKLNDLCRFSKDLSIYSAKVSSLIKEYNSLCLQASKGCQNKEQV--LQQRFRTAFRDFQQWLVNAKVTTAKCFDIPQSVSEVSANLQKIQECLSESEN-GQHKLQTVMTRGELLYSILTEEKAKVTRQKMLTAKDDWKGFISSLHQKESALENLQIQMKDFETSADPVQTWLSATEKI-VRDSNNRLH--DLP----SKKKEQQKLQSILEEISSHEPQITRLKEKAQQLREGQSACKSFAHRGSQLSAQYLALSSLTKEKMSRMDRIVAEHQQFSQGMIELEDWISE-AIHMLQSYCHPTADRSVLDSRMSKLEALLLVKQEKEIEMNMLLSRGE------------SVVRNTSPEGAPAIQNQLQDLKNTWASLLLSCIQCKSHLEGALSKWTSYQD 3319
BLAST of Nesprin-1 vs. Ensembl Xenopus
Match: SYNE1 (spectrin repeat containing, nuclear envelope 1 [Source:NCBI gene;Acc:100145637]) HSP 1 Score: 216.853 bits (551), Expect = 8.032e-55 Identity = 175/514 (34.05%), Postives = 279/514 (54.28%), Query Frame = 2
Query: 215 KTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXXXXXALGM--------------ANDPNAK------VKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNM--EEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENIS-----EEITAEINSGLMSMVQPPNELDIVKDFN---DKVDKNFENL-----NSKNNYDIFADLMSQ----RDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLMEPF--PNVHDKTFNDKVLQKLKEHESIFNKKNDVLAKFREVLQNPPANISP---KQLEAMKTRMENVCKAEGPVREKLNIFGIQANL-------KNKAQKWAVDLNSWDS 1603
+T +++ S+L Q+ PP++I +L +D+ DG L+ LLE+L+ L E+ + +++IH ++NI AL+F+E ++IKLVNIN +D+ DG+P+IVLGL+WT IL+FQIEE L Q M A P K ++G AKK L+ W + + G+ +KDFG SW +G AF+++++ I P LV+M E++++ TN+E LE AF+IAENELGIP+LLD EDVDV+KPDEKSIMTY+AQFLK YP+ P + S + + A + + +++D ++ +K+ + ++ Y F Q R ++ L+ + D L LD V+Q ++K ++ +W LDK LP LG+ I SWL AE ++ E H++T N + +KL++H+ + + F+E+ ++ N P +QLE M R V + KL ++ L ++K + W + DS
Sbjct: 7 ETLNQYVISFL-QRHPPMVINELFEDIKDGTKLIALLEVLSGQKLPCEQGRQLKRIHWVANIGAALKFLEG-RRIKLVNINSTDIADGRPSIVLGLIWTIILYFQIEELTSNLPQLHAMSSSTSSVDSVVSSEAASPPIKRKIVNKIQGSAKKALLRWVQYTAAKRLGIEVKDFGPSWRNGIAFHSVIYAIRPDLVDMDIEKLKRRTNRENLEEAFSIAENELGIPRLLDPEDVDVDKPDEKSIMTYIAQFLKHYPD---PHHTSLDGQEDSVMAGGTPSFSRSSKHREDRIVLRDMKVWLEQFEKDISRAQMVESSPQDRYQSFKQYRVQYEVKRKQVEALIHPLGKDGKLSLDQTMVKQA---WEKVSSRIFDWHLQLDKSLPAPLGT-IASWLYRAEVAMREEIVVQQSHEETAN-IMHRKLEQHKDVLKNLDGYKKAFQEIHRSRSVNGIPVPIEQLEDMAERFSYVASSSHLHMIKLEFMELKYRLLALLVLAESKLKSWIIKYGRRDS 510 HSP 2 Score: 90.1225 bits (222), Expect = 1.343e-16 Identity = 118/512 (23.05%), Postives = 222/512 (43.36%), Query Frame = 2
Query: 10796 ETAENELETLKANWSKLSKRI------------------NELNNLKMDLDKALEHFNIWLNNSCKWFVNITE-----TRKKVFESNETLQMKNNLQALKDDITEHKVDLSRLQTFVDSLMKICND-ETFQKTLDEITKEYNVLFNKCQNECDKCDHLIKLMTKYEISRADVLHWIEASTQTLLKCSDYTLKQSQMKSKLLMIDNLEKELENYGQSKFVEAIQDGEELLGELAGMPMQIVQQQMADLKSDWMEISRQLNQLSSNLRNTTSRSEAFKEMSNRLSNWLDDIEHTGLMDLSHIEHQCEIPFESGNSSSKHDRAKTLLTELNRHKQDFLQLANLATEL-----ANPSFDIENSQIQNRYIRLSNNLKDKIEKLNKQQADYDQIKQDIEEMEKWVFQTSIRIINENAEQGK---TTNNTIQEIET--LIKHSNEIIANILSQEPEIVKIGQAVDSLINISNNKNSDKEKELQDDLSKLIENFNNLKSSSIHKRDHLKDSVKKWDTYQD 12229
E +NE+ +L+A+W + I E +N L+ A++ F+ +L KW + + T K++ E + + K+ L AL D EH D L+T ++ L + D + + + KEYN L + C + + L ++ + D W+ + T KC D S++ + L I E EN GQ K + GE L L ++ +Q+M K DW L+Q S L N + + F+ ++ + WL E + D ++ H ++P + + + +++L E++ H+ +L A +L A SF SQ+ +Y+ LS+ K+K+ ++++ A++ Q Q + E+E W+ + +I ++ ++ + ++E L+K EI N+L E ++ N + + +Q+ L L + +L S I + HL+ ++ KW +YQD
Sbjct: 2800 EQMDNEIHSLQADWKQWEDSICHSQKALDGLLNQMAISEQEFSNQVSKLEDAIQDFSFFLE---KWTQKLNQGEGKDTDKEIVE--QWHRQKDVLTALND--AEHVTD--ELKTKLNDLCRFSKDLSIYSAKVSSLIKEYNSLCLQASKGCQNKEQV--LQQRFRTAFRDFQQWLVNAKVTTAKCFDIPQSVSEVSANLQKIQECLSESEN-GQHKLQTVMTRGELLYSILTEEKAKVTRQKMLTAKDDWKGFISSLHQKESALENLQIQMKDFETSADPVQTWLSATEKI-VRDSNNRLH--DLP----SKKKEQQKLQSILEEISSHEPQITRLKEKAQQLREGQSACKSFAHRGSQLSAQYLALSSLTKEKMSRMDRIVAEHQQFSQGMIELEDWISE-AIHMLQSYCHPTADRSVLDSRMSKLEALLLVKQEKEIEMNMLLSRGE------------SVVRNTSPEGAPAIQNQLQDLKNTWASLLLSCIQCKSHLEGALSKWTSYQD 3279
BLAST of Nesprin-1 vs. Ensembl Xenopus
Match: SYNE1 (spectrin repeat containing, nuclear envelope 1 [Source:NCBI gene;Acc:100145637]) HSP 1 Score: 216.468 bits (550), Expect = 9.186e-55 Identity = 175/514 (34.05%), Postives = 279/514 (54.28%), Query Frame = 2
Query: 215 KTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXXXXXALGM--------------ANDPNAK------VKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNM--EEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENIS-----EEITAEINSGLMSMVQPPNELDIVKDFN---DKVDKNFENL-----NSKNNYDIFADLMSQ----RDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLMEPF--PNVHDKTFNDKVLQKLKEHESIFNKKNDVLAKFREVLQNPPANISP---KQLEAMKTRMENVCKAEGPVREKLNIFGIQANL-------KNKAQKWAVDLNSWDS 1603
+T +++ S+L Q+ PP++I +L +D+ DG L+ LLE+L+ L E+ + +++IH ++NI AL+F+E ++IKLVNIN +D+ DG+P+IVLGL+WT IL+FQIEE L Q M A P K ++G AKK L+ W + + G+ +KDFG SW +G AF+++++ I P LV+M E++++ TN+E LE AF+IAENELGIP+LLD EDVDV+KPDEKSIMTY+AQFLK YP+ P + S + + A + + +++D ++ +K+ + ++ Y F Q R ++ L+ + D L LD V+Q ++K ++ +W LDK LP LG+ I SWL AE ++ E H++T N + +KL++H+ + + F+E+ ++ N P +QLE M R V + KL ++ L ++K + W + DS
Sbjct: 7 ETLNQYVISFL-QRHPPMVINELFEDIKDGTKLIALLEVLSGQKLPCEQGRQLKRIHWVANIGAALKFLEG-RRIKLVNINSTDIADGRPSIVLGLIWTIILYFQIEELTSNLPQLHAMSSSTSSVDSVVSSEAASPPIKRKIVNKIQGSAKKALLRWVQYTAAKRLGIEVKDFGPSWRNGIAFHSVIYAIRPDLVDMDIEKLKRRTNRENLEEAFSIAENELGIPRLLDPEDVDVDKPDEKSIMTYIAQFLKHYPD---PHHTSLDGQEDSVMAGGTPSFSRSSKHREDRIVLRDMKVWLEQFEKDISRAQMVESSPQDRYQSFKQYRVQYEVKRKQVEALIHPLGKDGKLSLDQTMVKQA---WEKVSSRIFDWHLQLDKSLPAPLGT-IASWLYRAEVAMREEIVVQQSHEETAN-IMHRKLEQHKDVLKNLDGYKKAFQEIHRSRSVNGIPVPIEQLEDMAERFSYVASSSHLHMIKLEFMELKYRLLALLVLAESKLKSWIIKYGRRDS 510 HSP 2 Score: 90.1225 bits (222), Expect = 1.424e-16 Identity = 118/512 (23.05%), Postives = 222/512 (43.36%), Query Frame = 2
Query: 10796 ETAENELETLKANWSKLSKRI------------------NELNNLKMDLDKALEHFNIWLNNSCKWFVNITE-----TRKKVFESNETLQMKNNLQALKDDITEHKVDLSRLQTFVDSLMKICND-ETFQKTLDEITKEYNVLFNKCQNECDKCDHLIKLMTKYEISRADVLHWIEASTQTLLKCSDYTLKQSQMKSKLLMIDNLEKELENYGQSKFVEAIQDGEELLGELAGMPMQIVQQQMADLKSDWMEISRQLNQLSSNLRNTTSRSEAFKEMSNRLSNWLDDIEHTGLMDLSHIEHQCEIPFESGNSSSKHDRAKTLLTELNRHKQDFLQLANLATEL-----ANPSFDIENSQIQNRYIRLSNNLKDKIEKLNKQQADYDQIKQDIEEMEKWVFQTSIRIINENAEQGK---TTNNTIQEIET--LIKHSNEIIANILSQEPEIVKIGQAVDSLINISNNKNSDKEKELQDDLSKLIENFNNLKSSSIHKRDHLKDSVKKWDTYQD 12229
E +NE+ +L+A+W + I E +N L+ A++ F+ +L KW + + T K++ E + + K+ L AL D EH D L+T ++ L + D + + + KEYN L + C + + L ++ + D W+ + T KC D S++ + L I E EN GQ K + GE L L ++ +Q+M K DW L+Q S L N + + F+ ++ + WL E + D ++ H ++P + + + +++L E++ H+ +L A +L A SF SQ+ +Y+ LS+ K+K+ ++++ A++ Q Q + E+E W+ + +I ++ ++ + ++E L+K EI N+L E ++ N + + +Q+ L L + +L S I + HL+ ++ KW +YQD
Sbjct: 2826 EQMDNEIHSLQADWKQWEDSICHSQKALDGLLNQMAISEQEFSNQVSKLEDAIQDFSFFLE---KWTQKLNQGEGKDTDKEIVE--QWHRQKDVLTALND--AEHVTD--ELKTKLNDLCRFSKDLSIYSAKVSSLIKEYNSLCLQASKGCQNKEQV--LQQRFRTAFRDFQQWLVNAKVTTAKCFDIPQSVSEVSANLQKIQECLSESEN-GQHKLQTVMTRGELLYSILTEEKAKVTRQKMLTAKDDWKGFISSLHQKESALENLQIQMKDFETSADPVQTWLSATEKI-VRDSNNRLH--DLP----SKKKEQQKLQSILEEISSHEPQITRLKEKAQQLREGQSACKSFAHRGSQLSAQYLALSSLTKEKMSRMDRIVAEHQQFSQGMIELEDWISE-AIHMLQSYCHPTADRSVLDSRMSKLEALLLVKQEKEIEMNMLLSRGE------------SVVRNTSPEGAPAIQNQLQDLKNTWASLLLSCIQCKSHLEGALSKWTSYQD 3305
BLAST of Nesprin-1 vs. Ensembl Mouse
Match: Syne1 (spectrin repeat containing, nuclear envelope 1 [Source:MGI Symbol;Acc:MGI:1927152]) HSP 1 Score: 253.062 bits (645), Expect = 1.148e-70 Identity = 198/598 (33.11%), Postives = 318/598 (53.18%), Query Frame = 2
Query: 185 LKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXX---------------XXXXALGMANDPN-----AKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNELDIVKDFNDKVDKNFENLNSKNNYDIFADLMSQ----RDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLME--PFPNVHDKTFNDKVLQKLKEHESIFNKKNDVLAKFREVLQNPPAN---ISPKQLEAMKTRMENVCKAEGPVREKLNIFGIQANLKNKAQKWAVDLNSWDSPIQSKQDLLDKIEQFNISMENGTSMDKFTSQLDELVKRKVKFCKENPVLD--EDLLNFINKAINECEEENDILPEKFESTLMKLENLSSEWDEISD 1885
L+DEQE +QK+TFTKW+NS+L ++KPP+++ DL +D+ DG+ LL LLE+L+ L E+ +++IH ++NI TAL+F+E +KIKLVNIN +D+ DG+P+IVLGL+WT IL+FQIEE + + A+ P+ AK++G AKK L+ W + + G+ +KDFG+SW G AF++++H I P LV++E+++ +N+E LE+AF IAE +LGIP+LLD EDVDV+KPDEKSIMTYVAQFL YP+ +E + ++ ++ I + D + ++ Y F Q R ++ ++ + D L LD V+Q +++ +L +W LDK LP LG+ IG+WL AE +L E VH++T N + +KL++H+ + + F E+ Q N + P QLE M R V K+ ++ L + L SW ++ + ++ + +EN +++ L + + K ++ E+++ F+++A + L + S LE + S WD D
Sbjct: 21 LQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGIKLLALLEVLSGQKLPCEQGHRVKRIHAVANIGTALKFLEG-RKIKLVNINATDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSMVSTETASPPSKRKVAAKIQGNAKKTLLKWVQHTAGKQMGIEVKDFGKSWRTGLAFHSVIHAIQPELVDLEKVKTRSNRENLEDAFTIAETQLGIPRLLDPEDVDVDKPDEKSIMTYVAQFLTQYPDIHGAGCDGQEDDRDDR-----LILKETKVWIEQFERDFTRAQMTESSLQDKYQAFKHFRVQYEMKRKQVEHIIQPLQRDGKLTLDQALVKQC---WERVSSRLFDWHIQLDKSLPAPLGT-IGAWLYRAEVALREEITIQQVHEETANT-IQRKLEQHKDLLQNTDAHKRAFHEIYQTRSVNGIPMPPDQLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRESVELLLQSYISFIENSKFFEQYEVTYQILKQTADIYVKAEGSVEEAENVMKFMSEATAQWRN----LSVEVRSVRSMLEEVISNWDRYGD 603
BLAST of Nesprin-1 vs. Ensembl Mouse
Match: Syne1 (spectrin repeat containing, nuclear envelope 1 [Source:MGI Symbol;Acc:MGI:1927152]) HSP 1 Score: 248.825 bits (634), Expect = 2.756e-65 Identity = 172/480 (35.83%), Postives = 267/480 (55.62%), Query Frame = 2
Query: 185 LKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKK------IKLVNINPSDVVDGKPAIVLGLVWT---------------AXXXXXXXXXXXXXXXALGMANDPN-----AKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNELDIVKD---FNDKVDKNFENLNS-----KNNYDIFADLMSQ----RDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLME--PFPNVHDKTFNDKVLQKLKEHESIFNKKNDVLAKFREVLQNPPAN---ISPKQLEAMKTRMENV 1495
L+DEQE +QK+TFTKW+NS+L ++KPP+++ DL +D+ DG+ LL LLE+L+ L E+ +++IH ++NI TAL+F+E K IKLVNIN +D+ DG+P+IVLGL+WT + + + A+ P+ AK++G AKK L+ W + + G+ +KDFG+SW G AF++++H I P LV++E+++ +N+E LE+AF IAE +LGIP+LLD EDVDV+KPDEKSIMTYVAQFL YP+ +G ++ I+K+ + ++ +++F ++ Y F Q R ++ ++ + D L LD V+Q +++ +L +W LDK LP LG+ IG+WL AE +L E VH++T N + +KL++H+ + + F E+ Q N + P QLE M R V
Sbjct: 21 LQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGIKLLALLEVLSGQKLPCEQGHRVKRIHAVANIGTALKFLEGRKSMYRGSPIKLVNINATDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSMVSTETASPPSKRKVAAKIQGNAKKTLLKWVQHTAGKQMGIEVKDFGKSWRTGLAFHSVIHAIQPELVDLEKVKTRSNRENLEDAFTIAETQLGIPRLLDPEDVDVDKPDEKSIMTYVAQFLTQYPDIH-------------GAGCDGQEDDRDDRLILKETKVWIEQFERDFTRAQMTESSLQDKYQAFKHFRVQYEMKRKQVEHIIQPLQRDGKLTLDQALVKQC---WERVSSRLFDWHIQLDKSLPAPLGT-IGAWLYRAEVALREEITIQQVHEETANT-IQRKLEQHKDLLQNTDAHKRAFHEIYQTRSVNGIPMPPDQLEDMAERFHFV 482
BLAST of Nesprin-1 vs. Ensembl Mouse
Match: Syne1 (spectrin repeat containing, nuclear envelope 1 [Source:MGI Symbol;Acc:MGI:1927152]) HSP 1 Score: 250.751 bits (639), Expect = 3.561e-65 Identity = 172/480 (35.83%), Postives = 267/480 (55.62%), Query Frame = 2
Query: 185 LKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKK------IKLVNINPSDVVDGKPAIVLGLVWT---------------AXXXXXXXXXXXXXXXALGMANDPN-----AKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNELDIVKD---FNDKVDKNFENLNS-----KNNYDIFADLMSQ----RDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLME--PFPNVHDKTFNDKVLQKLKEHESIFNKKNDVLAKFREVLQNPPAN---ISPKQLEAMKTRMENV 1495
L+DEQE +QK+TFTKW+NS+L ++KPP+++ DL +D+ DG+ LL LLE+L+ L E+ +++IH ++NI TAL+F+E K IKLVNIN +D+ DG+P+IVLGL+WT + + + A+ P+ AK++G AKK L+ W + + G+ +KDFG+SW G AF++++H I P LV++E+++ +N+E LE+AF IAE +LGIP+LLD EDVDV+KPDEKSIMTYVAQFL YP+ +G ++ I+K+ + ++ +++F ++ Y F Q R ++ ++ + D L LD V+Q +++ +L +W LDK LP LG+ IG+WL AE +L E VH++T N + +KL++H+ + + F E+ Q N + P QLE M R V
Sbjct: 21 LQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGIKLLALLEVLSGQKLPCEQGHRVKRIHAVANIGTALKFLEGRKSMYRGSPIKLVNINATDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSMVSTETASPPSKRKVAAKIQGNAKKTLLKWVQHTAGKQMGIEVKDFGKSWRTGLAFHSVIHAIQPELVDLEKVKTRSNRENLEDAFTIAETQLGIPRLLDPEDVDVDKPDEKSIMTYVAQFLTQYPDIH-------------GAGCDGQEDDRDDRLILKETKVWIEQFERDFTRAQMTESSLQDKYQAFKHFRVQYEMKRKQVEHIIQPLQRDGKLTLDQALVKQC---WERVSSRLFDWHIQLDKSLPAPLGT-IGAWLYRAEVALREEITIQQVHEETANT-IQRKLEQHKDLLQNTDAHKRAFHEIYQTRSVNGIPMPPDQLEDMAERFHFV 482 HSP 2 Score: 65.855 bits (159), Expect = 1.988e-9 Identity = 81/393 (20.61%), Postives = 174/393 (44.27%), Query Frame = 2
Query: 11108 FQKTLDEITKEYNVLFNKCQNECDKCDHLIKLMTKYEISRADVLHWIEASTQTLLKCSDYTLKQSQMKSKLLMIDNLEKELENYGQSKFVEAIQDGEELLGELAGMPMQIVQQQMADLKSDWMEISRQLNQLSSNLRNTTSRSEAFKEMSNRLSNWLDDIEHTGLMDLSHIEHQCEIPFESGNSSSKHDRAKTLLTELNRHKQDFLQLANLATEL-----ANPSFDIENSQIQNRYIRLSNNLKDKIEKLNKQQADYDQIKQDIEEMEKWVFQTSIRIINE---NAEQGKTTNNTIQEIETLIKHSNEIIANILSQEPEIVKIGQAVDSLINISNNKNSDKEKELQDDLSKLIENFNNLKSSSIHKRDHLKDSVKKWDTYQDFLQSTKLFLDN 12262
+ + + + KEYN L + C + + L +++ + W+ + T KC D S++ S L I E EN GQ K + GE L L Q VQ ++ K +W L+Q S L N + + F+ + + NWL E ++ ++ + + +++L E+ ++ +L A +L A+ SF SQ+ ++Y+ LSN K+K+ +L++ A++++ Q ++E++ W+ ++ +++ ++ + ++E L+ + QE EI ++ V + + + + +Q L + + + +L S++I + L+ ++ KW +YQD ++ ++D+
Sbjct: 3024 YSEKVSGLIKEYNCLCLQASKGCQNKEQI--LQERFQKASRGFQQWLVNAKITTAKCFDLPQNLSEVSSSLQKIQEFLSESEN-GQHKLNTMLFKGELLSSLLTEEKAQAVQAKVLTAKEEWKSFHANLHQKESALENLKIQMKDFEVSAELVQNWLSKTERL-------VQESSNRLYDLPAKRREQQKLQSVLEEIQCYEPQLHRLKEKARQLWEGQAASKSFVHRVSQLSSQYLALSNVTKEKVSRLDRIIAEHNRFSQGVKELQDWM-SDAVHMLDSYCLPTSDKSVLDSRMLKLEALLS---------VRQEKEI-QMKMVVTRGEYVLQSTSLEGSAAVQQQLQAVKDMWESLLSAAIRCKSQLEGALSKWTSYQDDVRQFSSWMDS 3395
BLAST of Nesprin-1 vs. Ensembl Mouse
Match: Syne2 (spectrin repeat containing, nuclear envelope 2 [Source:MGI Symbol;Acc:MGI:2449316]) HSP 1 Score: 181.03 bits (458), Expect = 3.858e-47 Identity = 154/464 (33.19%), Postives = 240/464 (51.72%), Query Frame = 2
Query: 185 LKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXX-------------XXXALGMANDP----------NAKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNELDIVKDFNDKVDKNFENLNSKNNYDIFADLMSQRDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLMEPFPNVHDKTFNDKVLQ-KLKEHESI---FNKKNDVLAKFREVLQNPPANISPKQLEAMKTRMENV 1495
L+ EQE QKKTFT W+NS L + PP ++ DL D+ G +LLDLLE+L+ L ++K N C NI AL F++N + IKL+NI+ +D+V+G P+I+LGL+WT ILHF IE+ + + A + P A+ + AKK L+ W + +N+ DF SW +G AF A++H + P L++M+ + +NK+ L+ AF IAE+EL IPKLL+ EDVDV PDEKSIMTYVAQFLK + P + ++ A++ L+ + E K D + + N + + + + S ++ + +D +S + D ++ + ++ W+ LD LP L E +WL+D E + E P + ++Q KL +S+ F+ +DVL F+ + + P +LE M R+ NV
Sbjct: 25 LQAEQEDTQKKTFTCWINSQLAKHTPPSVVSDLFADIKKGHVLLDLLEVLSGQQLPRDKGSNT--FQCRINIEHALTFLKN-RSIKLINIHVADIVEGNPSIILGLIWTIILHFHIEKLAQTLSCDYNQPSPEVVSVAASSPTSSPPTKKCSKAQAQARWQWSAKKALLQWAQEQCARSESVNVTDFKSSWRNGMAFLAVIHALRPDLIDMDSMRHRSNKDNLKEAFRIAEHELKIPKLLEPEDVDVVNPDEKSIMTYVAQFLKYSKDAPGPGDSTQ---AKVRDALVWLTL--QEKRFQKMLKDSASETYCN----KYHSLLSFMESLNEEKESFIDVLSLKGRMGELNEDESRLRQGWTSLMHQVAAWRAQLDDALPSPL-KETEAWLKDIEGVVQEGVPTSQSYSEARTLIQGKLSSFKSLMGSFDYHSDVLMAFQSNAEKSLPAVPPVKLEEMTRRINNV 475
BLAST of Nesprin-1 vs. Ensembl Mouse
Match: Syne2 (spectrin repeat containing, nuclear envelope 2 [Source:MGI Symbol;Acc:MGI:2449316]) HSP 1 Score: 181.8 bits (460), Expect = 2.184e-44 Identity = 154/464 (33.19%), Postives = 240/464 (51.72%), Query Frame = 2
Query: 185 LKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXX-------------XXXALGMANDP----------NAKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNELDIVKDFNDKVDKNFENLNSKNNYDIFADLMSQRDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLMEPFPNVHDKTFNDKVLQ-KLKEHESI---FNKKNDVLAKFREVLQNPPANISPKQLEAMKTRMENV 1495
L+ EQE QKKTFT W+NS L + PP ++ DL D+ G +LLDLLE+L+ L ++K N C NI AL F++N + IKL+NI+ +D+V+G P+I+LGL+WT ILHF IE+ + + A + P A+ + AKK L+ W + +N+ DF SW +G AF A++H + P L++M+ + +NK+ L+ AF IAE+EL IPKLL+ EDVDV PDEKSIMTYVAQFLK + P + ++ A++ L+ + E K D + + N + + + + S ++ + +D +S + D ++ + ++ W+ LD LP L E +WL+D E + E P + ++Q KL +S+ F+ +DVL F+ + + P +LE M R+ NV
Sbjct: 25 LQAEQEDTQKKTFTCWINSQLAKHTPPSVVSDLFADIKKGHVLLDLLEVLSGQQLPRDKGSNT--FQCRINIEHALTFLKN-RSIKLINIHVADIVEGNPSIILGLIWTIILHFHIEKLAQTLSCDYNQPSPEVVSVAASSPTSSPPTKKCSKAQAQARWQWSAKKALLQWAQEQCARSESVNVTDFKSSWRNGMAFLAVIHALRPDLIDMDSMRHRSNKDNLKEAFRIAEHELKIPKLLEPEDVDVVNPDEKSIMTYVAQFLKYSKDAPGPGDSTQ---AKVRDALVWLT--LQEKRFQKMLKDSASETYCN----KYHSLLSFMESLNEEKESFIDVLSLKGRMGELNEDESRLRQGWTSLMHQVAAWRAQLDDALPSPL-KETEAWLKDIEGVVQEGVPTSQSYSEARTLIQGKLSSFKSLMGSFDYHSDVLMAFQSNAEKSLPAVPPVKLEEMTRRINNV 475
BLAST of Nesprin-1 vs. UniProt/SwissProt
Match: sp|Q8NF91|SYNE1_HUMAN (Nesprin-1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=4) HSP 1 Score: 258.07 bits (658), Expect = 1.499e-66 Identity = 182/479 (38.00%), Postives = 269/479 (56.16%), Query Frame = 2
Query: 185 LKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAXX------------XXXXXXXXXXXXXALGMANDPN--------AKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNELD-----IVKDFNDKVDKNFENL--------NSKNNYDIFADLMSQ----RDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLMEPFP--NVHDKTFNDKVLQKLKEHESIFNKKNDVLAKFREVLQNPPAN---ISPKQLEAMKTRMENV 1495
L+DEQE +QK+TFTKW+NS+L ++KPP+++ DL +D+ DG+ LL LLE+L+ L E+ + M++IH ++NI TAL+F+E +KIKLVNIN +D+ DG+P+IVLGL+WT IL Q + ++ + P+ K++G AKK L+ W + G+ +KDFG+SW G AF++++H I P LV++E ++ +N+E LE+AF IAE ELGIP+LLD EDVDV+KPDEKSIMTYVAQFLK YP+ +E EI G S I K+ +++ +L N ++ Y F Q R ++ L+ + D L LD V+Q +D+ +L +W LDK LP LG+ IG+WL AE +L E VH++T N + +KL++H+ + + F E+ + N + P QLE M R V
Sbjct: 21 LQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGVKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEG-RKIKLVNINSTDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSIVSSETPSPPSKRKVTTKIQGNAKKALLKWVQYTAGKQTGIEVKDFGKSWRSGVAFHSVIHAIRPELVDLETVKGRSNRENLEDAFTIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDIHNASTDGQE-DDEILPGFPSFANSVQNFKREDRVIFKEMKVWIEQFERDLTRAQMVESNLQDKYQSFKHFRVQYEMKRKQIEHLIQPLHRDGKLSLDQALVKQ---SWDRVTSRLFDWHIQLDKSLPAPLGT-IGAWLYRAEVALREEITVQQVHEETANT-IQRKLEQHKDLLQNTDAHKRAFHEIYRTRSVNGIPVPPDQLEDMAERFHFV 492 HSP 2 Score: 81.2629 bits (199), Expect = 3.683e-13 Identity = 158/754 (20.95%), Postives = 305/754 (40.45%), Query Frame = 2
Query: 10796 ETAENELETLKANW------------------SKLSKRINELNNLKMDLDKALEHFNIWLNNSCKWFVNITETRKKVFESNETLQMKNNLQALKDDITEHKVDLSRLQTFVDSLMKICND-ETFQKTLDEITKEYNVLFNKCQNECDKCDHLIKLMTKYEISRADVLHWIEASTQTLLKCSDYTLKQSQMKSKLLMIDNLEKELENYGQSKFVEAIQDGEELLGELAGMPMQIVQQQMADLKSDWMEISRQLNQLSSNLRNTTSRSEAFKEMSNRLSNWLDDIEHTGLMDLSHIEHQCEIPFESGNSSSKHDRAKTLLTELNRHKQDFLQLANLATEL-----ANPSFDIENSQIQNRYIRLSNNLKDKIEKLNKQQADYDQIKQDIEEMEKWVFQTSIRIINENAEQGKTTNNTIQEIETL-------IKHSNEIIANILSQEPEIVKIGQAVDSLINISNNKNSDKEKELQDDLSKLIENFNNLKSSSIHKRDHLKDSVKKWDTYQDFLQSTKLFLDNELPNWWRERNQDQMKSAYSNFN-NEPILKEILDMDNKLNGLKTTMELEAKACDGILPTIAITASRSQTPNFKSNRSLYSPSSNWSTNKSDVTPNDELIPNILSKSIYEDLDENIKKVSNLKKEIIEK----ITDWNNFNREKTSFKNWMDNEMLKFS--SVLYTEPGISNFASLQKSKLKEIQEEMNY--KKQALLNLNTHFKE--LTSNVSGAADLVLKNLNQDFDETEKKIS 12931
E E++ L+A+W S+++ E + L++ALE F+ L W +T K + E ++ + Q + D + + + L++ ++ L + D T+ + + KEYN L + C + + L ++ + D W+ + T KC D S++ + L I E EN GQ K + GE L L + +Q ++ K DW L+Q S L N + + F+ + + +WL E + ++ + + +++L E++ ++ +L A +L A+ SF SQ+ ++Y+ LSN K+K+ +L++ A+++Q I+E++ W+ +I +++ T++ ++ + TL +K EI Q IV G++V N + + +Q L + + + +L S+ I + L+ ++ KW +YQD ++ + W M S +N N +E E+ D L K E E + +L TI + + T ++ + L +DL E + + KE + K + + R+ +F+ W+ E K SVL + A ++ L+++QE + + QALLN H +E + S + A D L++L QD+ + ++S
Sbjct: 2917 ELMHTEMQALRADWKQWEDSVFQTQSCLENLVSQMALSEQEFSGQVAQLEQALEQFSALLKT---WAQQLTLLEGKNTD-EEIVECWHKGQEILDALQKAEPRTEDLKSQLNELCRFSRDLSTYSGKVSGLIKEYNCLCLQASKGCQNKEQI--LQQRFRKAFRDFQQWLVNAKITTAKCFDIPQNISEVSTSLQKIQEFLSESEN-GQHKLNMMLSKGELLSTLLTKEKAKGIQAKVTAAKEDWKNFHSNLHQKESALENLKIQMKDFEVSAEPIQDWLSKTEKM-------VHESSNRLYDLPAKRREQQKLQSVLEEIHCYEPQLNRLKEKAQQLWEGQAASKSFRHRVSQLSSQYLALSNLTKEKVSRLDRIVAEHNQFSLGIKELQDWM-TDAIHMLDSYCH--PTSDKSVLDSRTLKLEALLSVKQEKEI------QMKMIVTRGESV------LQNTSPEGIPTIQQQLQSVKDMWASLLSAGIRCKSQLEGALSKWTSYQDGVR--------QFSGW--------MDSMEANLNESERQHAELRDKTTMLGKAKLLNE-EVLSYSSLLETIEVKGA-GMTEHYVTQLEL------------------------------QDLQERYRAIQERAKEAVTKSEKLVRLHQEYQRDLKAFEVWLGQEQEKLDQYSVLEGD------AHTHETTLRDLQELQVHCAEGQALLNSVLHTREDVIPSGIPQAEDRALESLRQDWQAYQHRLS 3587
BLAST of Nesprin-1 vs. UniProt/SwissProt
Match: sp|Q6ZWR6|SYNE1_MOUSE (Nesprin-1 OS=Mus musculus OX=10090 GN=Syne1 PE=1 SV=2) HSP 1 Score: 257.299 bits (656), Expect = 2.582e-66 Identity = 176/480 (36.67%), Postives = 274/480 (57.08%), Query Frame = 2
Query: 185 LKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWT---------------AXXXXXXXXXXXXXXXALGMANDPN-----AKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYP-------EGKKPENISEEITAEINSGLMSMVQPPNELDI--VKDFNDKVDKNFENLNS-----KNNYDIFADLMSQ----RDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLME--PFPNVHDKTFNDKVLQKLKEHESIFNKKNDVLAKFREVLQNPPAN---ISPKQLEAMKTRMENV 1495
L+DEQE +QK+TFTKW+NS+L ++KPP+++ DL +D+ DG+ LL LLE+L+ L E+ +++IH ++NI TAL+F+E +KIKLVNIN +D+ DG+P+IVLGL+WT + + + A+ P+ AK++G AKK L+ W + + G+ +KDFG+SW G AF++++H I P LV++E+++ +N+E LE+AF IAE +LGIP+LLD EDVDV+KPDEKSIMTYVAQFL YP +G++ + + T N L+ Q + L + K + ++ +++F ++ Y F Q R ++ ++ + D L LD V+Q +++ +L +W LDK LP LG+ IG+WL AE +L E VH++T N + +KL++H+ + + F E+ Q N + P QLE M R V
Sbjct: 21 LQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGIKLLALLEVLSGQKLPCEQGHRVKRIHAVANIGTALKFLEG-RKIKLVNINATDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSMVSTETASPPSKRKVAAKIQGNAKKTLLKWVQHTAGKQMGIEVKDFGKSWRTGLAFHSVIHAIQPELVDLEKVKTRSNRENLEDAFTIAETQLGIPRLLDPEDVDVDKPDEKSIMTYVAQFLTQYPDIHGAGCDGQEDDVVFVGFTN--NIALLLGFQRDDRLILKETKVWIEQFERDFTRAQMTESSLQDKYQAFKHFRVQYEMKRKQVEHIIQPLQRDGKLTLDQALVKQC---WERVSSRLFDWHIQLDKSLPAPLGT-IGAWLYRAEVALREEITIQQVHEETANT-IQRKLEQHKDLLQNTDAHKRAFHEIYQTRSVNGIPMPPDQLEDMAERFHFV 492 HSP 2 Score: 66.2402 bits (160), Expect = 1.147e-8 Identity = 81/393 (20.61%), Postives = 174/393 (44.27%), Query Frame = 2
Query: 11108 FQKTLDEITKEYNVLFNKCQNECDKCDHLIKLMTKYEISRADVLHWIEASTQTLLKCSDYTLKQSQMKSKLLMIDNLEKELENYGQSKFVEAIQDGEELLGELAGMPMQIVQQQMADLKSDWMEISRQLNQLSSNLRNTTSRSEAFKEMSNRLSNWLDDIEHTGLMDLSHIEHQCEIPFESGNSSSKHDRAKTLLTELNRHKQDFLQLANLATEL-----ANPSFDIENSQIQNRYIRLSNNLKDKIEKLNKQQADYDQIKQDIEEMEKWVFQTSIRIINE---NAEQGKTTNNTIQEIETLIKHSNEIIANILSQEPEIVKIGQAVDSLINISNNKNSDKEKELQDDLSKLIENFNNLKSSSIHKRDHLKDSVKKWDTYQDFLQSTKLFLDN 12262
+ + + + KEYN L + C + + L +++ + W+ + T KC D S++ S L I E EN GQ K + GE L L Q VQ ++ K +W L+Q S L N + + F+ + + NWL E ++ ++ + + +++L E+ ++ +L A +L A+ SF SQ+ ++Y+ LSN K+K+ +L++ A++++ Q ++E++ W+ ++ +++ ++ + ++E L+ + QE EI ++ V + + + + +Q L + + + +L S++I + L+ ++ KW +YQD ++ ++D+
Sbjct: 3034 YSEKVSGLIKEYNCLCLQASKGCQNKEQI--LQERFQKASRGFQQWLVNAKITTAKCFDLPQNLSEVSSSLQKIQEFLSESEN-GQHKLNTMLFKGELLSSLLTEEKAQAVQAKVLTAKEEWKSFHANLHQKESALENLKIQMKDFEVSAELVQNWLSKTERL-------VQESSNRLYDLPAKRREQQKLQSVLEEIQCYEPQLHRLKEKARQLWEGQAASKSFVHRVSQLSSQYLALSNVTKEKVSRLDRIIAEHNRFSQGVKELQDWM-SDAVHMLDSYCLPTSDKSVLDSRMLKLEALLS---------VRQEKEI-QMKMVVTRGEYVLQSTSLEGSAAVQQQLQAVKDMWESLLSAAIRCKSQLEGALSKWTSYQDDVRQFSSWMDS 3405
BLAST of Nesprin-1 vs. UniProt/SwissProt
Match: sp|Q6ZWQ0|SYNE2_MOUSE (Nesprin-2 OS=Mus musculus OX=10090 GN=Syne2 PE=1 SV=2) HSP 1 Score: 181.415 bits (459), Expect = 1.661e-43 Identity = 154/464 (33.19%), Postives = 240/464 (51.72%), Query Frame = 2
Query: 185 LKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXX-------------XXXALGMANDP----------NAKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNELDIVKDFNDKVDKNFENLNSKNNYDIFADLMSQRDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLMEPFPNVHDKTFNDKVLQ-KLKEHESI---FNKKNDVLAKFREVLQNPPANISPKQLEAMKTRMENV 1495
L+ EQE QKKTFT W+NS L + PP ++ DL D+ G +LLDLLE+L+ L ++K N C NI AL F++N + IKL+NI+ +D+V+G P+I+LGL+WT ILHF IE+ + + A + P A+ + AKK L+ W + +N+ DF SW +G AF A++H + P L++M+ + +NK+ L+ AF IAE+EL IPKLL+ EDVDV PDEKSIMTYVAQFLK + P + ++ A++ L+ + E K D + + N + + + + S ++ + +D +S + D ++ + ++ W+ LD LP L E +WL+D E + E P + ++Q KL +S+ F+ +DVL F+ + + P +LE M R+ NV
Sbjct: 25 LQAEQEDTQKKTFTCWINSQLAKHTPPSVVSDLFADIKKGHVLLDLLEVLSGQQLPRDKGSNT--FQCRINIEHALTFLKN-RSIKLINIHVADIVEGNPSIILGLIWTIILHFHIEKLAQTLSCDYNQPSPEVVSVAASSPTSSPPTKKCSKAQAQARWQWSAKKALLQWAQEQCARSESVNVTDFKSSWRNGMAFLAVIHALRPDLIDMDSMRHRSNKDNLKEAFRIAEHELKIPKLLEPEDVDVVNPDEKSIMTYVAQFLKYSKDAPGPGDSTQ---AKVRDALVWLT--LQEKRFQKMLKDSASETYCN----KYHSLLSFMESLNEEKESFIDVLSLKGRMGELNEDESRLRQGWTSLMHQVAAWRAQLDDALPSPL-KETEAWLKDIEGVVQEGVPTSQSYSEARTLIQGKLSSFKSLMGSFDYHSDVLMAFQSNAEKSLPAVPPVKLEEMTRRINNV 475
BLAST of Nesprin-1 vs. UniProt/SwissProt
Match: sp|Q8WXH0|SYNE2_HUMAN (Nesprin-2 OS=Homo sapiens OX=9606 GN=SYNE2 PE=1 SV=3) HSP 1 Score: 180.259 bits (456), Expect = 4.138e-43 Identity = 167/506 (33.00%), Postives = 261/506 (51.58%), Query Frame = 2
Query: 179 VLLKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXXXXXALGM-------------ANDPNAK----VKGQ----AKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNELD-IVKDFNDKVDKNFENLNSKNNYDIFADLMSQRDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLMEPFPNVHDKTFNDKVLQ-KLKEHESI---FNKKNDVLAKFREVLQNPPANISPKQLEAMKTRMENVCKAEGPV-----REKLNIFGIQANLKNKAQKWAVDLNSWDS 1603
+ L+ EQE QKK FT W+NS L + P +I DL D+ G +LLDLLE+L+ L ++K N C NI AL F+ N + IKL+NI+ +D++DG P+I+LGL+WT ILHF IE+ + L A+ P AK V+ + A+K L+ W + +N+ DF SW +G AF A++H + P L++M+ ++ +NK+ L AF IAE EL IP+LL+ EDVDV PDEKSIMTYVAQFL+ K EE ++ + + +L ++KD + D F+ NS + + + S ++ K LD +S LD D Q+ +D + ++N W+ L+ LP L + +WLQ+ EE + E D + ++Q K+ +S+ F +++L F +N + P +LE MK R+ N+ + + + K + G+ +K+K W + S +S
Sbjct: 23 ISLQAEQEDTQKKAFTCWINSQLARHTSPSVISDLFTDIKKGHVLLDLLEVLSGQQLPRDKGSNT--FQCRINIEHALTFLRN-RSIKLINIHVTDIIDGNPSIILGLIWTIILHFHIEKLAQTLSCNYNQPSLDDVSVVDSSPASSPPAKKCSKVQARWQMSARKALLLWAQEQCATYESVNVTDFKSSWRNGMAFLAIIHALRPDLIDMKSVKHRSNKDNLREAFRIAEQELKIPRLLEPEDVDVVDPDEKSIMTYVAQFLQY---SKDAPGTGEEAQGKVKDAMGWLTLQKEKLQKLLKDSEN--DTYFKKYNS-----LLSFMESFNEEKKSFLDVLSIKRDLDELDKDHLQLREAWDGLDHQINAWKIKLNYALPPPL-HQTEAWLQEVEELMDEDLSASQDHSQAVTLIQEKMTLFKSLMDRFEHHSNILLTFENKDENHLPLVPPNKLEEMKRRINNILEKKFILLLEFHYYKCLVLGLVDEVKSKLDIWNIKYGSRES 514
BLAST of Nesprin-1 vs. UniProt/SwissProt
Match: sp|Q96JQ2|CLMN_HUMAN (Calmin OS=Homo sapiens OX=9606 GN=CLMN PE=1 SV=1) HSP 1 Score: 150.984 bits (380), Expect = 8.660e-35 Identity = 110/297 (37.04%), Postives = 174/297 (58.59%), Query Frame = 2
Query: 185 LKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWT----------AXXXXXXXXXXXXXXXALGMAND------PNAK------VKGQAK--KGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNE 1003
L+ E+E +QK+TFT+W+N +L + PP+ +KDL D+ DG +L+ LLE+L+ L E + +I L+NI AL+F+E D +KLV+I+ +++ DG P++VLGL+W + + G +D P A+ VK Q K K L+AW + KYG+ ++DF SW G AF A++ IDP+LV+M++ + + +E LE AF+IA++ L IP+LL+ ED+ V+ PDE+SIMTYVAQFL+ +PE + + + I S + + + P+E
Sbjct: 26 LQVERENVQKRTFTRWINLHLEKCNPPLEVKDLFVDIQDGKILMALLEVLSGRNLLHEYKSSSHRIFRLNNIAKALKFLE-DSNVKLVSIDAAEIADGNPSLVLGLIWNIILFFQIKELTGNLSRNSPSSSLSPGSGGTDSDSSFPPTPTAERSVAISVKDQRKAIKALLAWVQRK-TRKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALENSTRENLEKAFSIAQDALHIPRLLEPEDIMVDTPDEQSIMTYVAQFLERFPELEAEDIFDSDKEVPIESTFVRIKETPSE 320
BLAST of Nesprin-1 vs. TrEMBL
Match: A0A267EWS2 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig031215g1 PE=4 SV=1) HSP 1 Score: 339.347 bits (869), Expect = 3.103e-90 Identity = 215/483 (44.51%), Postives = 302/483 (62.53%), Query Frame = 2
Query: 146 MDRKDTVVKKGVLLKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXXXXXALGMAN--DPNAKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEG--KKPENIS--EEITAEINSGLMSMVQPPNELDIVKDFNDKVDKNFENLNSKN-----NYDIFADLMSQRDDMK----LLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLMEPFPNVH----DKTFNDKVLQKLKEHESIFNKKNDVLAKFREVLQNPPANISPKQLEAMKTRMENVCKAEGPVREKLNIF 1537
M R+ + + L+DEQE++QKKTFT W+N+YL Q +PP I DL ++ DG+ LL LLE+L+ L E K MQ++HCLSN+RTAL F+E+ KKIKLVNINP+D+VDGKP+IVLGL+WT IL+FQIEEQE+ ++++L + K KG AKK L+AW N L DKY ++I+DFG SW DG AFNA+VHNIDP+LV+ME++ TN+E LE AF AE+ L IP+L+D EDVDV+KPDEKSIMTYVAQFLK+YPEG KKP+ + E+ +++ + + Q N+L + DF + V++ NY F + Q+ +K LL + + + L L ++V + + +LNEW+W LD LPG LG ++G WL AE L EPFP+ D+ + Q+L EH +IF + F+E ++ + +QL + R+ V + E VR+KL
Sbjct: 1 MQRRQSFMSNVKNLRDEQERVQKKTFTNWINTYLIQCQPPCKIADLFPEVKDGIKLLLLLEVLSGQKLPHESRKVMQRVHCLSNVRTALSFLES-KKIKLVNINPADIVDGKPSIVLGLIWTIILYFQIEEQEDTIMKSLEGTELAERGEKFKGSAKKALLAWAQNNLGDKYAIDIRDFGNSWRDGSAFNAMVHNIDPSLVDMEKLGDRTNRENLEAAFAAAESGLNIPRLIDPEDVDVDKPDEKSIMTYVAQFLKAYPEGSKKKPKLLEQIEDAQSKVEAAKQAAEQERNDLRKISDFCEAVERELPTSGKGRGDPVENYKKFEEFRQQQAALKEAYEALLKRRADGHLLTLKPDEVDALEAQWRAASDQLNEWRWQLDSALPGDLG-KVGGWLARAERCLREPFPDTAAGEPDEAIAQALHQRLTEHRAIFADAPAMRKAFQEARKSAGRGLPAEQLADIDRRLTQVQQDEPEVRQKLEFL 481
BLAST of Nesprin-1 vs. TrEMBL
Match: A0A267EZS9 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig015905g1 PE=4 SV=1) HSP 1 Score: 338.961 bits (868), Expect = 9.518e-90 Identity = 214/481 (44.49%), Postives = 299/481 (62.16%), Query Frame = 2
Query: 146 MDRKDTVVKKGVLLKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXXXXXALGMAN--DPNAKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEG--KKPENISEEITAEINSGLMSMVQPPNELDIVKDFNDKVDKNFENLNSKN-----NYDIFADLMSQRDDMK----LLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLMEPFPNVH----DKTFNDKVLQKLKEHESIFNKKNDVLAKFREVLQNPPANISPKQLEAMKTRMENVCKAEGPVREKLNIF 1537
M R+ + + L+DEQE++QKKTFT W+N+YL Q +PP I DL ++ DG+ LL LLE+L+ L E K MQ++HCLSN+RTAL F+E+ KKIKLVNINP+D+VDGKP+IVLGL+WT IL+FQIEEQE+ ++++L + K KG AKK L+AW N L DKY ++I+DFG SW DG AFNA+VHNIDP+LV+ME++ TN+E LE AF AE+ L IP+L+D EDVDV+KPDEKSIMTYVAQFLK+YPEG KKP ++ ++ + + Q N+L + DF + V++ NY F + Q+ +K LL + + + L L ++V + + +LNEW+W LD LPG LG ++G WL AE L EPFP+ D+ + Q+L EH +IF + F+E ++ + +QL + R+ V + E VR+KL
Sbjct: 1 MQRRQSFMSNVKNLRDEQERVQKKTFTNWINTYLIQCQPPCKIADLFPEVKDGIKLLLLLEVLSGQKLPHESRKVMQRVHCLSNVRTALSFLES-KKIKLVNINPADIVDGKPSIVLGLIWTIILYFQIEEQEDTIMKSLEGTELAERGEKFKGSAKKALLAWAQNNLGDKYAIDIRDFGNSWRDGSAFNAMVHNIDPSLVDMEKLGDRTNRENLEAAFAAAESGLNIPRLIDPEDVDVDKPDEKSIMTYVAQFLKAYPEGSKKKP-----KLLEQVEAAKQAAEQERNDLRKISDFCEAVERELPTSGKGRGDPVENYKKFEEFRQQQAALKEAYEALLKRRADGHLLTLKPDEVDALEAQWRAASDQLNEWRWQLDSALPGDLG-KVGGWLARAERCLREPFPDTAAGEPDEAIAQALHQRLTEHRAIFADAPAMRKAFQEARKSAGRGLPAEQLADIDRRLTQVQQDEPEVRQKLEFL 474
BLAST of Nesprin-1 vs. TrEMBL
Match: A0A1I8GMD0 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 319.701 bits (818), Expect = 5.630e-87 Identity = 223/552 (40.40%), Postives = 324/552 (58.70%), Query Frame = 2
Query: 152 RKDTVVKKGVLLKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXXXXXALGMAN--DPNAKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPE-NISEEITAEINSGLMSMVQPPNELDIVKDFNDKVDKNFENLNSKNNYDIFADLMSQRDDMKLL---LDKMSTDN-YLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLME--PFPNVHDKTFNDKVLQKLKEHESIFNK-KNDVLAKFREVLQNPPANISPKQLEAMKTRMENVCKAEGPVREKLNIFGIQANLKNKAQKWAVDLNSWDSPIQSKQDLLDKIEQFNISMENGTSMDKFTSQLDELVKRKVKFCKENPVLDEDLLNFIN 1777
R+ +++ L+DEQE++QKKTFT W+N+YL +PP I DL ++ DG LL LLE+L+ L+KE NMQ++HCLSN+RTAL F+E+ K+IKLVNINP+D+VDGKP IVLGL+WT IL+FQIEEQE+ + ++L + KG AKK L+AW N L DKY +++KDFG SW DG AFNA+VHNIDP+LV+M+ + +N+E LE AF AEN L IP+LLD+EDVDV+KPDEKSIMTY+AQFLK+YPEG K + +++ A +G + +LD + DF KV+ N +Y A+L ++RD+++ L K S D L DV + + + + +L + +W LD LPG G IG WL AE L + P + D + +++ ++L+EH +F++ V + + PPA +S Q+ M TR+ V E VR +L + L + L W +Q++ D +N + +G +D LD L K+ K +P + F++
Sbjct: 2 RRSSLMTNVKSLRDEQERVQKKTFTNWINTYLITCQPPCKISDLFTEIKDGTRLLLLLEVLSGNKLQKENRGNMQRVHCLSNVRTALSFLES-KQIKLVNINPADIVDGKPTIVLGLMWTIILYFQIEEQEDMIRKSLEGTELAERGELFKGSAKKALLAWAQNNLGDKYDVDLKDFGSSWRDGAAFNAMVHNIDPSLVDMDALRSRSNRENLEAAFQAAENGLNIPRLLDAEDVDVDKPDEKSIMTYIAQFLKAYPEGGKNRPKLQDQLDAARQAGEKERL----DLDSINDFCRKVESEAPN----GDYQTLAELQAERDNLQPSVEDLAKRSKDGRLLSTPPADVDAALAAWRQADDQLRKLRWRLDAELPGDFG-RIGQWLGRAEACLYQDWPADDAPDDSAAEELSERLREHNEVFSEDPQSVRRDLQAARRAPPAGVSDAQIANMDTRLGRVIADEPDVRRRLEFLEPKRRLLASLAQCERKLPLWTGKCGKQQEVEDLFSDYNAFVIDGKLVDGVEQALDSLRKQAEPMRKRDPSGSREADRFLS 543
BLAST of Nesprin-1 vs. TrEMBL
Match: A0A267F524 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig010703g1 PE=4 SV=1) HSP 1 Score: 320.857 bits (821), Expect = 1.013e-83 Identity = 223/552 (40.40%), Postives = 324/552 (58.70%), Query Frame = 2
Query: 152 RKDTVVKKGVLLKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXXXXXALGMAN--DPNAKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPE-NISEEITAEINSGLMSMVQPPNELDIVKDFNDKVDKNFENLNSKNNYDIFADLMSQRDDMKLL---LDKMSTDN-YLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLME--PFPNVHDKTFNDKVLQKLKEHESIFNKK-NDVLAKFREVLQNPPANISPKQLEAMKTRMENVCKAEGPVREKLNIFGIQANLKNKAQKWAVDLNSWDSPIQSKQDLLDKIEQFNISMENGTSMDKFTSQLDELVKRKVKFCKENPVLDEDLLNFIN 1777
R+ +++ L+DEQE++QKKTFT W+N+YL +PP I DL ++ DG LL LLE+L+ L+KE NMQ++HCLSN+RTAL F+E+ K+IKLVNINP+D+VDGKP IVLGL+WT IL+FQIEEQE+ + ++L + KG AKK L+AW N L DKY +++KDFG SW DG AFNA+VHNIDP+LV+M+ + +N+E LE AF AEN L IP+LLD+EDVDV+KPDEKSIMTY+AQFLK+YPEG K + +++ A +G + +LD + DF KV+ N +Y A+L ++RD+++ L K S D L DV + + + + +L + +W LD LPG G IG WL AE L + P + D + +++ ++L+EH +F++ V + + PPA +S Q+ M TR+ V E VR +L + L + L W +Q++ D +N + +G +D LD L K+ K +P + F++
Sbjct: 2 RRSSLMTNVKSLRDEQERVQKKTFTNWINTYLISCQPPCKISDLFTEIKDGTRLLLLLEVLSGNKLQKENRGNMQRVHCLSNVRTALSFLES-KQIKLVNINPADIVDGKPTIVLGLMWTIILYFQIEEQEDMIRKSLEGTELAERGELFKGSAKKALLAWAQNNLGDKYDVDLKDFGSSWRDGAAFNAMVHNIDPSLVDMDALRSRSNRENLEAAFQAAENGLNIPRLLDAEDVDVDKPDEKSIMTYIAQFLKAYPEGGKNRPKLQDQLDAARQAGEKERL----DLDSINDFCRKVESEAPN----GDYQTLAELQAERDNLQPSVEDLAKRSKDGRLLSTPPADVDAALAAWRQADDQLRKLRWRLDAELPGDFGR-IGQWLGRAEACLYQDWPADDAPDDSAAEELSERLREHNEVFSEDPQSVRRDLQAARRAPPAGVSDAQIANMDTRLGRVIADEPDVRRRLEFLEPKRRLLASLAQCERKLPLWTGKCGKQQEVEDLFSDYNAFVIDGKLVDGVEQALDSLRKQAEPMRKRDPSGSREADRFLS 543
BLAST of Nesprin-1 vs. TrEMBL
Match: A0A1I8GVC4 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 319.701 bits (818), Expect = 3.031e-83 Identity = 224/557 (40.22%), Postives = 324/557 (58.17%), Query Frame = 2
Query: 137 TD*MDRKDTVVKKGVLLKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXXXXXALGMAN--DPNAKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPE-NISEEITAEINSGLMSMVQPPNELDIVKDFNDKVDKNFENLNSKNNYDIFADLMSQRDDMKLL---LDKMSTDN-YLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLME--PFPNVHDKTFNDKVLQKLKEHESIFNK-KNDVLAKFREVLQNPPANISPKQLEAMKTRMENVCKAEGPVREKLNIFGIQANLKNKAQKWAVDLNSWDSPIQSKQDLLDKIEQFNISMENGTSMDKFTSQLDELVKRKVKFCKENPVLDEDLLNFIN 1777
D +D D + V+ + EQE++QKKTFT W+N+YL +PP I DL ++ DG LL LLE+L+ L+KE NMQ++HCLSN+RTAL F+E+ K+IKLVNINP+D+VDGKP IVLGL+WT IL+FQIEEQE+ + ++L + KG AKK L+AW N L DKY +++KDFG SW DG AFNA+VHNIDP+LV+M+ + +N+E LE AF AEN L IP+LLD+EDVDV+KPDEKSIMTY+AQFLK+YPEG K + +++ A +G + +LD + DF KV+ N +Y A+L ++RD+++ L K S D L DV + + + + +L + +W LD LPG G IG WL AE L + P + D + +++ ++L+EH +F++ V + + PPA +S Q+ M TR+ V E VR +L + L + L W +Q++ D +N + +G +D LD L K+ K +P + F++
Sbjct: 558 ADGVDITDVIDAAIVIFRYEQERVQKKTFTNWINTYLITCQPPCKISDLFTEIKDGTRLLLLLEVLSGNKLQKENRGNMQRVHCLSNVRTALSFLES-KQIKLVNINPADIVDGKPTIVLGLMWTIILYFQIEEQEDMIRKSLEGTELAERGELFKGSAKKALLAWAQNNLGDKYDVDLKDFGSSWRDGAAFNAMVHNIDPSLVDMDALRSRSNRENLEAAFQAAENGLNIPRLLDAEDVDVDKPDEKSIMTYIAQFLKAYPEGGKNRPKLQDQLDAARQAGEKERL----DLDSINDFCRKVESEAPN----GDYQTLAELQAERDNLQPSVEDLAKRSKDGRLLSTPPADVDAALAAWRQADDQLRKLRWRLDAELPGDFG-RIGQWLGRAEACLYQDWPADDAPDDSAAEELSERLREHNEVFSEDPQSVRRDLQAARRAPPAGVSDAQIANMDTRLGRVIADEPDVRRRLEFLEPKRRLLASLAQCERKLPLWTGKCGKQQEVEDLFSDYNAFVIDGKLVDGVEQALDSLRKQAEPMRKRDPSGSREADRFLS 1104
BLAST of Nesprin-1 vs. Ensembl Cavefish
Match: ENSAMXT00000039764.1 (pep primary_assembly:Astyanax_mexicanus-2.0:9:24167966:24185412:1 gene:ENSAMXG00000043596.1 transcript:ENSAMXT00000039764.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 246.514 bits (628), Expect = 3.802e-70 Identity = 176/436 (40.37%), Postives = 261/436 (59.86%), Query Frame = 2
Query: 194 EQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKK------IKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXXXXXALGMANDPNA--------------------KVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPE--NISEEITAEINSGLMSMVQPPNE--LDIVKDFNDKVDKNFENL-----NSKNNYDIFADLMSQ----RDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLME--PFPNVHDKTFNDKVLQKLKEHE 1378
EQE +QK+TFTKW+NS+L ++ PP+ I DL +D+ DG+ LL LLE+L+ L E+ + +++IH +SNI TAL+F+E + IKLVNIN +D+ DG+P+IVLGL+WT IL+FQIEE L ++N ++ K +G AK+ L+ W + + G+ +KDFG SW G AF+++++ I P LV+ME +++ +N+E LE AF +AENELGIP+LLD EDVDV+KPDEKSIMTYVAQFLK YP+ + E EE+ +NS L VQ L +K + D+++++ N + Y F + Q + ++ LL + D L +D V+Q +D+ ++L +W LDK LPG LG IG+WL AE +L E P H++T N + +KL++H+
Sbjct: 10 EQESVQKRTFTKWINSHLAKRNPPLEINDLFEDIKDGVKLLALLEVLSGQRLPSEQGRQLKRIHWVSNIGTALKFLEGRRSVYRGSPIKLVNINATDIADGRPSIVLGLMWTIILYFQIEELTSNLPALQALSNSASSVDSMASSETASPPMKRKVVTKFQGNAKRALLRWVQCTATKRLGIEVKDFGSSWRTGVAFHSVIYAIRPDLVDMELVKRRSNRENLEEAFTVAENELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDPHQSETDGQQEEV---LNSSLNVFVQREERKVLRELKAWLDQLERDILRAQGAEGNLSDKYQAFKNFRVQYEVRKKQVESLLQPVHRDGKLSVDQAVVKQ---SWDQVSVRLLDWHIHLDKSLPGPLGV-IGAWLHRAELALREDIPIQQAHEETAN-IIHRKLEQHK 437
BLAST of Nesprin-1 vs. Ensembl Cavefish
Match: ENSAMXT00000036923.1 (pep primary_assembly:Astyanax_mexicanus-2.0:9:24166584:24185412:1 gene:ENSAMXG00000043596.1 transcript:ENSAMXT00000036923.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 246.514 bits (628), Expect = 4.894e-70 Identity = 176/437 (40.27%), Postives = 262/437 (59.95%), Query Frame = 2
Query: 191 DEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKK------IKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXXXXXALGMANDPNA--------------------KVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPE--NISEEITAEINSGLMSMVQPPNE--LDIVKDFNDKVDKNFENL-----NSKNNYDIFADLMSQ----RDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLME--PFPNVHDKTFNDKVLQKLKEHE 1378
+EQE +QK+TFTKW+NS+L ++ PP+ I DL +D+ DG+ LL LLE+L+ L E+ + +++IH +SNI TAL+F+E + IKLVNIN +D+ DG+P+IVLGL+WT IL+FQIEE L ++N ++ K +G AK+ L+ W + + G+ +KDFG SW G AF+++++ I P LV+ME +++ +N+E LE AF +AENELGIP+LLD EDVDV+KPDEKSIMTYVAQFLK YP+ + E EE+ +NS L VQ L +K + D+++++ N + Y F + Q + ++ LL + D L +D V+Q +D+ ++L +W LDK LPG LG IG+WL AE +L E P H++T N + +KL++H+
Sbjct: 12 NEQESVQKRTFTKWINSHLAKRNPPLEINDLFEDIKDGVKLLALLEVLSGQRLPSEQGRQLKRIHWVSNIGTALKFLEGRRSVYRGSPIKLVNINATDIADGRPSIVLGLMWTIILYFQIEELTSNLPALQALSNSASSVDSMASSETASPPMKRKVVTKFQGNAKRALLRWVQCTATKRLGIEVKDFGSSWRTGVAFHSVIYAIRPDLVDMELVKRRSNRENLEEAFTVAENELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDPHQSETDGQQEEV---LNSSLNVFVQREERKVLRELKAWLDQLERDILRAQGAEGNLSDKYQAFKNFRVQYEVRKKQVESLLQPVHRDGKLSVDQAVVKQ---SWDQVSVRLLDWHIHLDKSLPGPLGV-IGAWLHRAELALREDIPIQQAHEETAN-IIHRKLEQHK 440
BLAST of Nesprin-1 vs. Ensembl Cavefish
Match: ENSAMXT00000045503.1 (pep primary_assembly:Astyanax_mexicanus-2.0:9:24166584:24193162:1 gene:ENSAMXG00000043596.1 transcript:ENSAMXT00000045503.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 252.292 bits (643), Expect = 1.651e-66 Identity = 188/522 (36.02%), Postives = 295/522 (56.51%), Query Frame = 2
Query: 191 DEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKK------IKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXXXXXALGMANDPNA--------------------KVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYP-------EGKKPENISEEITAEINSGLMSMVQPPNELDIVK------DFNDKVDKNFENLNSKNNYDIFADLMSQRDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLME--PFPNVHDKTFNDKVLQKLKEHESIFNKKNDVLAKFREVLQNPPANISP---KQLEAMKTRMENVCKAEGPVREKLNIFGIQANL-------KNKAQKWAVDLNSWDS 1603
+EQE +QK+TFTKW+NS+L ++ PP+ I DL +D+ DG+ LL LLE+L+ L E+ + +++IH +SNI TAL+F+E + IKLVNIN +D+ DG+P+IVLGL+WT IL+FQIEE L ++N ++ K +G AK+ L+ W + + G+ +KDFG SW G AF+++++ I P LV+ME +++ +N+E LE AF +AENELGIP+LLD EDVDV+KPDEKSIMTYVAQFLK YP +G++ E ++ E+ + L + E DI++ + +DK + F+N + Y++ ++ ++ LL + D L +D V+Q +D+ ++L +W LDK LPG LG IG+WL AE +L E P H++T N + +KL++H+ + F+++ ++ N P +QL+ M R V + KL + ++ L ++K + W + DS
Sbjct: 12 NEQESVQKRTFTKWINSHLAKRNPPLEINDLFEDIKDGVKLLALLEVLSGQRLPSEQGRQLKRIHWVSNIGTALKFLEGRRSVYRGSPIKLVNINATDIADGRPSIVLGLMWTIILYFQIEELTSNLPALQALSNSASSVDSMASSETASPPMKRKVVTKFQGNAKRALLRWVQCTATKRLGIEVKDFGSSWRTGVAFHSVIYAIRPDLVDMELVKRRSNRENLEEAFTVAENELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDPHQSETDGQQEEREERKVLRELKAWLDQL-----ERDILRAQGAEGNLSDKY-QAFKNF--RVQYEV------RKKQVESLLQPVHRDGKLSVDQAVVKQ---SWDQVSVRLLDWHIHLDKSLPGPLGV-IGAWLHRAELALREDIPIQQAHEETANI-IHRKLEQHKDVLTNLEGHRQAFQQIHRDRSVNGVPVPAEQLQDMAERFNFVSTSSHVHLIKLEFWEMKYRLMAFLILAESKLKSWIIKYGRRDS 514
BLAST of Nesprin-1 vs. Ensembl Cavefish
Match: syne1a (spectrin repeat containing, nuclear envelope 1a [Source:ZFIN;Acc:ZDB-GENE-030131-4172]) HSP 1 Score: 229.18 bits (583), Expect = 7.612e-59 Identity = 202/636 (31.76%), Postives = 326/636 (51.26%), Query Frame = 2
Query: 185 LKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXXXXXALG--------------------MANDPNAKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNEL--DIVKDFNDKVDKNFENLNSKNNYDIFADLMSQRDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLM-EPFPNVHDKTFNDKVLQKLKEHESIFNKKNDVLAKFREVLQNPPANISP---KQLEAMKTRMENVCKAEGPVREKLNIFGIQANL-------KNKAQKWAVDLNSWDSPIQSKQDLLDKIEQFNISMENGTSMDKFTSQLDELVKRKVKFCKENPVLDEDLLNFINKAINECEEENDILPEKFESTLMKLENLSSEWDEISDGEQKIETFSRRLSKALQLDDFQQQRSLVDQLPEVLD 1993
L+DEQE +QK+TFTKW+NS+L ++ PP+++KDL +D+ DG++LL LLE+L+ L E+ + +++IH L+N+ TAL F+E ++IKLVNIN +DVVDG+P+IVLGL+WT IL+FQIEE L G + P +G AK+ L+ W + + GL++KDFG SW G AF+A++ + P LVNME + N+ LE AF++AE ELGIP+LLD EDVDV+KPDEKSIMTYVAQFLK +P+G + E++ ++ E L + ++L D + DK D + S Y + +L +R + L D L D +Q +++ +L +W LD LP LG+ +G WL AE+ L EP P + + + Q L++H+ I F+++ ++ + P +QL+ M R+ + + KL + ++ + ++K + W V +++ Q LL F +E K+ S ++L + V + + +E + F+ ++ L + S L+ + W++ S ++ + AL + +R LP +D
Sbjct: 35 LRDEQEAVQKRTFTKWINSHLAKRDPPLVVKDLYEDIKDGVMLLALLEVLSGHKLPCEQGRKLRRIHWLANVGTALRFLEG-RRIKLVNINTTDVVDGRPSIVLGLIWTIILYFQIEELTSSLPPQKGQNSSNSSVDSSNSTETASPPVKRKPRLSFQGGAKRALLKWVQRTATKRLGLDVKDFGPSWRSGVAFHAVIFALRPQLVNMERVWNRPNRANLEEAFSLAERELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHHPDGGEAESVGQQEEREQRKVLRELKVWADQLEKDCAQAQMDKGDPGHQ-YKSFKQYRVQYEL--KRRQVLSSLQSTQRDGILTSDQALFKQA---WERISTRLLDWHIQLDSALPNPLGA-VGIWLHQAEKILQEEPLPQQSHEQTANAIHQTLQQHQEILGLFETHQQTFQQLHRDRSVSGVPVPAEQLQDMAERLNYISTSSHVHLSKLEFWELKYRMLALLTLGESKLKSWIVKYGR----LETTQLLLQSYVSF---VEGQQFFQKYESLYEDLKQAAVLYTNADSSAEEAVRRFLRDMADQWRS----LAVEIRSVRSMLKEVEGNWEKYSSAVSSLQAWLEDAQVALHQPE-NTKREFFRNLPHWMD 650 HSP 2 Score: 63.929 bits (154), Expect = 6.202e-9 Identity = 84/377 (22.28%), Postives = 164/377 (43.50%), Query Frame = 2
Query: 11129 ITKEYNVLFNKCQNECDKCDHLIKLMTKYEISRADVLHWIEASTQTLLKCSDYTLKQSQMKSKLLMIDNLEKELENYGQSKFVEAIQDGEELLGELAGMPMQIVQQQMADLKSDWMEISRQLNQLSSNLRNTTSRSEAFKEMSNRLSNWLDDIEHTGLMDLSHIEHQCEIPFESGNSSSKHDRAKTLLTELNRHKQDFLQLANLATEL-----ANPSFDIENSQIQNRYIRLSNNLKDKIEKLNKQQADYDQIKQDIEEMEKWVFQTSIRIINENAEQGKTTNNTIQEIETLIKHSNEIIANILSQEPEI-----VKIGQAVDSLINISNNKNSDKEKELQDDLSKLIENFNNLKSSSIHKRDHLKDSVKKWDTYQD 12229
+ K +N L + EC + L++ ++ S D W+ + + KC D + + L I + E GQ++ + GE+L + ++ V+ + + DW + L Q + L+ SR +AF+E L +WL+ E T + D S H ++P + + +++L E+ + + L A L A F Q+ RY+ LSN K+K+ ++ + ++ Q ++E++ WV + +I+ E ++T + T + H +++ QE EI + G+AV N S K++QD L ++++ L S +I + L+ ++ W +YQ+
Sbjct: 2916 LIKLHNSLGLRASRECQNKEKLLE--QRFRSSLRDFRQWLVNANISTAKCFDSPHSIQEASAALQRIQEFMSDREQ-GQARLDAVLAHGEQLSAVVQADRVEAVRAKTSAASDDWRSLMDNLQQREAILQGLQSRMQAFEESLQPLQDWLNRTEIT-VQDSSTRLH--DLPAKRLELC----KLQSVLEEMCCREPELGGLRERAHSLWEGQAAGKGFVHRVCQLAARYLALSNRTKEKVSRIERVVGEHQLFSQGLQELQSWVSEAQ-KIL----ETCRSTTADKSMLVTRMGHLEDLLTA--RQEREIQLKMLITRGEAVQR--NTSAEGVPVVRKQIQD----LKDSWDLLLSGTIQCKSQLEGALSHWTSYQE 3269
BLAST of Nesprin-1 vs. Ensembl Cavefish
Match: MACF1 (microtubule actin crosslinking factor 1 [Source:HGNC Symbol;Acc:HGNC:13664]) HSP 1 Score: 155.606 bits (392), Expect = 4.179e-38 Identity = 104/284 (36.62%), Postives = 156/284 (54.93%), Query Frame = 2
Query: 158 DTVVKKGVLLKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXXXXXALGMANDPNAKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYP------EGKKPENISEEITAEINSGLMSMVQ 991
D + V + DE++++QKKTFTKW+N +L + + I + + + ++ + K + H L N++ AL+F++ +++KLVNI D+ DG P + LGL+WT ILHFQI E G + D AK K L+ WT A GL +F SW +GR FNAL+H P L++ME + + +N+E LE AF IAE+ LG+ +LLD+EDVDV PDEKS++TYV+ ++P EG P + + AE S S++Q
Sbjct: 54 DPAERAVVRVADERDRVQKKTFTKWVNKHLIKVRKHIT----DLYEDLRDGHNLISLLEVLSGVQLPREKGRMRFHRLQNVQIALDFLKQ-RQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISEIYVS-----GESGDLTAKEK------LLLWTQQATEGYPGLRCSNFSSSWSNGRMFNALLHRYRPDLIDMEVVARQSNRENLEQAFEIAES-LGVTRLLDAEDVDVPSPDEKSVITYVSSIYDAFPKIPEGGEGITPHEVDQRW-AEYQSRFSSLLQ 319
BLAST of Nesprin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009426.1 (pep scaffold:Pmarinus_7.0:GL476614:383620:553344:1 gene:ENSPMAG00000008375.1 transcript:ENSPMAT00000009426.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 194.126 bits (492), Expect = 6.246e-49 Identity = 153/409 (37.41%), Postives = 222/409 (54.28%), Query Frame = 2
Query: 191 DEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWT---------AXXXXXXXXXXXXXXXALGMANDPNAK---------VKGQAKKGLMAWTNNAL----SDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPEN--ISEEITAEINSGLMSMVQPPNELDIVK--DFNDKVDKNFENLN-------SKNNYDIFADLMSQRDDMK----LLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESL 1306
DEQE +QK+TFTKW+NS+L +PP+++ DL KDL DG+ L+ LLE+LT L E+ + +++IH LSNI TAL+FME ++IKLVNIN + DGKP+IVLGL+WT A + M A ++ AKK L+ W + S G I+DFG SW G AF+ ++ I P LVN+E++ + +N E LE AF +AE +LGIP+LLD +DVDV+KPDEK IMTYVAQFLK YP + E + +E+ V D +K + +++ ++++ K +Y F + +D K L+L + + L ++ + ++ D+D KL EWQ LD LP L +E+G WL E +L
Sbjct: 1 DEQEAVQKRTFTKWINSHLALVRPPLVVDDLFKDLRDGVKLIALLEVLTGERLPYEQGRQLKRIHALSNIGTALKFMEA-RRIKLVNINAPYIADGKPSIVLGLIWTIILYFQIEEATNNLLPISPWSSETSLSSMEGSSTASPQRKRRQTPMRSTAKKALLKWVQLVVPSLESRVGGTEIRDFGASWRTGIAFHLMIRAIQPELVNLEQVTQRSNHENLEEAFIVAEEKLGIPRLLDPKDVDVDKPDEKIIMTYVAQFLKHYPNAAESEGNLLGDEVCLSTIPTFALSVPKLQREDRIKFMELQAWLNQAIKDVSLQATPEALKEHYQAFRRIKVPYEDRKSTVLLMLQPLKGNGKLSVEQSTAKK---DWDLLSAKLWEWQGLLDGALPPPL-AEVGVWLHRVETAL 404 HSP 2 Score: 55.0694 bits (131), Expect = 6.557e-7 Identity = 63/301 (20.93%), Postives = 130/301 (43.19%), Query Frame = 2
Query: 11201 LMTKYEISRADVLHWIEASTQTLLKCSDYTLKQSQMKSKLLMIDNLEKELE-----NYGQSKFVEAIQDGEELLGELAGMPMQIVQQQMADLKSDWMEISRQLNQLSSNLRNTTSRSEAFKEMSNRLSNWLDDIEHTGLMDLSHIEHQCEIPFESGNSSSKHDRAKTLLTELNRHKQDFLQLANLATELANP------SFDIENSQIQNRYIRLSNNLKDKIEKLNKQQADYDQIKQDIEEMEKWVFQTSIRIINENAEQGKTT--NNTIQEIETLI--KHSNEIIANILSQEPEIVKIGQ 12058
L +++ + DV W+ + +L++ SD + ++ D+L+K E GQS+ GE L+ L VQ ++A + +W + LN+ + L+ + E + + + WL + E T L + Q ++P + R +++L ++ H +L A ++A SF + S + RY+ L+N KD+ ++ + ++ Q +Q E++ W+ + + + A G T + + ++E L+ + EI N++ + V I Q
Sbjct: 2737 LESRFRSALRDVQLWMAQARASLVQGSDTGVA--------VVTDSLQKTQEVLSQSEEGQSRLNTLASKGELLMSVLGHEEAGGVQAELASAREEWKALLGSLNKQEAQLQGLQEQLEELEASTAPVHKWLGETE-TSLAQAADGGAQADLPAKR----QLQRRLQSVLEDVACHAPQLARLRERAQQMAEACAPAAHSFGLRVSALNTRYLALANLAKDQAQRATRALQEHQQFEQGWRELQDWLADSRLLLDTYLAPSGDRTVLRSRLAKVEALVATRLEKEIQLNLVLSRGDTVLITQ 3024
BLAST of Nesprin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006506.1 (pep scaffold:Pmarinus_7.0:GL476558:286440:335800:-1 gene:ENSPMAG00000005865.1 transcript:ENSPMAT00000006506.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 151.754 bits (382), Expect = 4.755e-37 Identity = 88/242 (36.36%), Postives = 137/242 (56.61%), Query Frame = 2
Query: 185 LKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXXXXXALGMANDPNAKVKG-----QAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVA 895
L DE++++QKKTFTKW+NS+L Q + I + + + + + K ++H + NI+ L ++++ +++KLVNI D+VDG P + LGL+WT I L N A ++G Q+++ L+AW D GL+ +F SW DGR A+VH P LV++EE+ + ++ LE A ++AE+ELG+P+LLD EDVDV+ PDEKSI+TYV+
Sbjct: 1 LADERDRVQKKTFTKWINSHLQQVRMNI----GDLYEDLRDGQALISLLESLSGDCIIREKGRLRVHHVQNIQIVLNYLQH-QQVKLVNIRKEDIVDGNPKLTLGLIWTII---------------LHYQNASFAHIEGNHSSMQSRERLLAWARLVAKDVPGLSCHNFSSSWRDGRLLCAIVHAHRPGLVDLEEVRRRGARQNLEEALSLAESELGVPRLLDPEDVDVDAPDEKSIITYVS 222
BLAST of Nesprin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006515.1 (pep scaffold:Pmarinus_7.0:GL476558:286719:335794:-1 gene:ENSPMAG00000005865.1 transcript:ENSPMAT00000006515.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 145.591 bits (366), Expect = 1.993e-35 Identity = 87/237 (36.71%), Postives = 135/237 (56.96%), Query Frame = 2
Query: 191 DEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXXXXXALGMANDPNAKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQF 901
DE++++QKKTFTKW+NS+L Q + I + + + + + K ++H + NI+ L ++++ +++KLVNI D+VDG P + LGL+WT ILH+Q+ A G+ + L+AW D GL+ +F SW DGR A+VH P LV++EE+ + ++ LE A ++AE+ELG+P+LLD EDVDV+ PDEKSI+TYV+
Sbjct: 1 DERDRVQKKTFTKWINSHLQQVRMNI----GDLYEDLRDGQALISLLESLSGDCIIREKGRLRVHHVQNIQIVLNYLQH-QQVKLVNIRKEDIVDGNPKLTLGLIWTIILHYQVS------------AGQVGGGTPGRER--LLAWARLVAKDVPGLSCHNFSSSWRDGRLLCAIVHAHRPGLVDLEEVRRRGARQNLEEALSLAESELGVPRLLDPEDVDVDAPDEKSIITYVSAL 218
BLAST of Nesprin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002838.1 (pep scaffold:Pmarinus_7.0:GL477168:22072:87306:1 gene:ENSPMAG00000002584.1 transcript:ENSPMAT00000002838.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 145.976 bits (367), Expect = 3.753e-35 Identity = 96/271 (35.42%), Postives = 144/271 (53.14%), Query Frame = 2
Query: 179 VLLKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXXXXXALGMANDPNAKVKGQ-----AKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGL 976
+L+ DE++++QKKTFTKW+N +L + + + + + + K + K + H L N++ AL+F+ ++IKLVNI D+ DG P + LGL+WT ILHFQI + +V GQ AK L+ W+ + G+ +F SW DGR FNA++H P L++M+ + N+E LE AF +AE ++G+ +LLD EDVDV PDEKSI+TYV+ P + P E+NSGL
Sbjct: 2 LLIADERDRVQKKTFTKWVNKHLMKVRKHV----NDMYEDLRDGHNLISLLEVLSGEKLPREKGRMRFHRLHNVQIALDFLRL-RQIKLVNIRSDDIADGNPKLTLGLIWTIILHFQI----------------ADIQVSGQSEDMTAKDRLLLWSQRMVEGYPGIRCDNFTTSWRDGRLFNAIIHRHRPELIDMKRVAVRANRENLEQAFTVAERDMGVTRLLDPEDVDVPSPDEKSIITYVSSLYDVIP--RMP---------EVNSGL 240
BLAST of Nesprin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008111.1 (pep scaffold:Pmarinus_7.0:GL478136:8967:48859:1 gene:ENSPMAG00000007298.1 transcript:ENSPMAT00000008111.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 145.976 bits (367), Expect = 1.637e-34 Identity = 92/247 (37.25%), Postives = 141/247 (57.09%), Query Frame = 2
Query: 185 LKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXXXXXALGMANDPNAKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGK 925
L DE+E +QKKTFTKW+NS+L + I + +L L + + + +IHCL N+ AL+F++ ++K+ L N+ D+VDG ++LGL+WT IL FQI++ + + + N K + AK L+ W + +NI +F SW DG AFNA+VH P L+ ++++K L+NAFNIAE +LG+ KLLD ED+ V++PDEKSI+TYV + + + K
Sbjct: 51 LADEREAVQKKTFTKWVNSHLARVSCRIT---DLYTDLRDGRMLIKLLEVLSGEKLPKPTRGKMRIHCLENVDKALQFLK-EQKVHLENMGSHDIVDGNHRLILGLIWTIILRFQIQD--------ISVETEDN-KERRSAKDALLLWCQMKTAGYQNVNIHNFTTSWRDGLAFNAIVHKHRPDLIEFDKLKKSNAHHNLQNAFNIAEQKLGLTKLLDPEDISVDQPDEKSIITYVVTYYHYFSKMK 284
BLAST of Nesprin-1 vs. Ensembl Nematostella
Match: EDO37708 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SF38]) HSP 1 Score: 149.443 bits (376), Expect = 3.141e-35 Identity = 95/249 (38.15%), Postives = 142/249 (57.03%), Query Frame = 2
Query: 191 DEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXXXXXALGMANDPNAKVKGQ------AKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDV-EKPDEKSIMTYVAQFLKSYP 916
D ++ +QKKTFTKW+N+ L + + ++ L LL + +K + + + + H L N++TALEF+E+ KKIKLVNI D+VDG P + LGL+WT IL+F ND + ++ G+ AK L+ W+ +++K+F SW DG AFNA++H P LV+ ++ K + + +E AF++AE EL +P+LLD EDV V E PDEKSIMTYVA + +P
Sbjct: 33 DHRDAVQKKTFTKWVNNRLLK----VGVRILDLYEELRDGEDLLLLLEVLCNVKLPRERGLLRFHMLQNVQTALEFLES-KKIKLVNIRSDDIVDGNPKLTLGLIWTIILYF--------------QINDLDVEIAGEKVQDLSAKDALLHWSKKVTQGYPKVDVKNFSSSWRDGFAFNAIIHRYRPDLVDFSKLSKTSPEANIEYAFHVAEKELNVPRLLDVEDVVVSENPDEKSIMTYVASLYEVFP 262
BLAST of Nesprin-1 vs. Ensembl Nematostella
Match: EDO29101 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T4L2]) HSP 1 Score: 131.339 bits (329), Expect = 3.258e-32 Identity = 95/257 (36.96%), Postives = 149/257 (57.98%), Query Frame = 2
Query: 185 LKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXXXXXALGMANDPNAKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEIT 955
LK+E+ QKKTFTKW+NS+L + + + + DL +DL+DG +L+ LLEI++ + ++H + N+ ALEF++ K +KL +I DVVDG ++LGL+W IL FQI + D +K + AK+ L+ W ++I++F SW +G AFNAL+H P L++ + ++ L NAF +AE +LGI +LLD+EDVD +PD++S+MTYVA + + + + K E I
Sbjct: 17 LKNERIFSQKKTFTKWVNSFLDKVRSGLHVNDLFEDLADGKILISLLEIISGEKIGFAARGKF-RVHNIQNVNKALEFLQ--KSVKLESIGAEDVVDGNERLILGLIWMIILRFQIADISY---------QDDMSKERKSAKEALLLWCQRMTRGYPDVDIQNFSTSWRNGLAFNALLHKHRPDLIDYATLRPSQHEANLNNAFTVAEEKLGITRLLDAEDVDCPRPDDRSVMTYVAAYYQYFAKLKSEETGGRRIA 261
BLAST of Nesprin-1 vs. Ensembl Nematostella
Match: EDO37406 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFT6]) HSP 1 Score: 124.79 bits (312), Expect = 4.784e-31 Identity = 96/261 (36.78%), Postives = 144/261 (55.17%), Query Frame = 2
Query: 191 DEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDG----------------KPAIVLGLVWTAXXXXXXXXXXXXXXXALGMANDPNAKVKG--------QAKKGLMAWTNNALSDKYGLN--IKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVA 895
D+QEK+QKKTFTKWMN YL + KP + + D+ +L DG LL LLE+L+ L+KE+ ++ H L+N+ ++F+ +KK+KLVNI+P +VDG + + + + + + A + ++++G + +K ++ W A S G N IKDF SW G+AF ++H+ P LVN+ I + N L AF++A L +PKLL+ EDVDVEKPDEKSIMTY+A
Sbjct: 7 DDQEKIQKKTFTKWMNFYLAKSKPSVQVDDIFTELQDGTKLLTLLEVLSGEKLRKERGN--KRPHQLANLGHVIDFL-TEKKVKLVNIHPESIVDGNTTIILGLLWIIIHHYQSSKIAQNIKAQRSLSEKYRIVPASNSLVPCAFETISQIQGFYATKKKVRTRKFMLEWAKKATSKASGSNEAIKDFSTSWRTGQAFLQIIHSFRPDLVNIATIAERDNITNLTEAFDLAYTHLNVPKLLEPEDVDVEKPDEKSIMTYMA 264
BLAST of Nesprin-1 vs. Ensembl Nematostella
Match: EDO42431 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1C0]) HSP 1 Score: 135.191 bits (339), Expect = 5.247e-31 Identity = 99/251 (39.44%), Postives = 146/251 (58.17%), Query Frame = 2
Query: 182 LLKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXXXXXALGMANDPNAKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPE 934
+L DE+E++QKKTFTKW+NS+L ++ + +L DL DG L+ LLE+L+ L K M +IH L N+ +L F++ +++ L N+ D+VDG I LGL+WT IL FQI+ + + K AK L+ W + + I +F SW DG AFNA++H P L+ E++ K ++ LE AF +AE +LGI LLD+EDV+V+ PDEKSI+TYVA + + + K E
Sbjct: 17 VLADERERVQKKTFTKWINSHL--QRVGARVNELYHDLQDGRKLILLLEVLSGEKLPKPSKGRM-RIHNLENVEKSLVFLKK-QRVHLENVGAHDIVDGNQKITLGLIWTIILRFQIQ----------DITIEGETTEKRSAKDALLLWCQSKTVGYVHVTITNFTTSWRDGLAFNAIIHRHRPDLIEFEKLTKADAEQNLEQAFEVAETQLGITPLLDAEDVNVDFPDEKSILTYVAAYYHYFAKMKTVE 253
BLAST of Nesprin-1 vs. Ensembl Nematostella
Match: EDO49576 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGP7]) HSP 1 Score: 130.183 bits (326), Expect = 7.178e-30 Identity = 96/257 (37.35%), Postives = 148/257 (57.59%), Query Frame = 2
Query: 185 LKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXXXXXALGMANDPNAKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEIT 955
LK+E+ QKKTFTKW+NS+L K + + DL +DL+DG +L+ LLEI++ + ++H + N+ ALEF++ K +KL +I DVVDG ++LGL+W IL FQI + D +K + AK+ L+ W G++I++F SW +G AFNAL+H P L++ + ++ L NAF +A +LGI +LLD+EDVD +PD++S+MTYVA + + + + K E I
Sbjct: 17 LKNERIFSQKKTFTKWVNSFL--DKSGLHVNDLFEDLADGKILISLLEIISGEKIGFAARGKF-RVHNIQNVNKALEFLQ--KSVKLESIGAEDVVDGNERLILGLIWMIILRFQIADISY---------QDDMSKERKSAKEALLLWCQRMTRGYPGVDIQNFSTSWRNGLAFNALLHKHRPDLIDYATLRPSQHEANLNNAFTVAAEKLGITRLLDAEDVDCPRPDDRSVMTYVAAYYQYFAKLKSEETGGRRIA 259
BLAST of Nesprin-1 vs. Ensembl Medaka
Match: ENSORLT00000000374.2 (pep primary_assembly:ASM223467v1:22:316712:329038:1 gene:ENSORLG00000000306.2 transcript:ENSORLT00000000374.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 241.506 bits (615), Expect = 4.544e-66 Identity = 179/468 (38.25%), Postives = 260/468 (55.56%), Query Frame = 2
Query: 194 EQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWT---------------AXXXXXXXXXXXXXXXALGMANDPN-----AKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNELDIVKDFNDKVDKNF-----ENLNSKNNYDIFADLMSQ----RDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLMEPFPNVHDKTFNDKVL-QKLKEHESIFNKKNDVLAKFREVLQNPPAN---ISPKQLEAMKTRMENVC 1498
EQE +QK+TFTKW+NS+L + + DL +D+ DG+ LL LLE+L+ L E+ +++++IH +SNI TAL+F+E +KIKLVNI+ +DV DG+P+IVLGL+WT A+ F L + + P K +G AKK L+ W + +G+ +KDFG SW DG AF ++VH I P LV+MEE+ + +N+E LE AF++AENELGIP+LLD EDVDV+KPDEKSIMTYVAQFLK YP E + + L + L +K F D+++K+ + N + Y +F Q + + LL + D L +D V+Q +D +L +W LDK LPG LGS IG+WL AE +L E FP H VL +KL++H+ + F+++ ++ + + P+QL+ M R V
Sbjct: 5 EQEAVQKRTFTKWINSHLEK------MNDLFEDIKDGVKLLALLEVLSGQRLPCEQGRHLKRIHWVSNISTALKFLEG-RKIKLVNIHATDVADGRPSIVLGLIWTIILYFQIEELTSNLPALQAFSNSSSSVDSLTSSETGSPPVKRKVLHKFQGNAKKVLLRWVQCTAAKHHGIEVKDFGPSWRDGVAFQSMVHAIRPDLVDMEEVRRRSNRENLEEAFSLAENELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPNPGPAAGQQEVLLWPADCNLTR--EERKMLRELKVFLDQLEKDVLRAQGSDGNLSDKYQVFKHFHVQFEMKKKQAEPLLQPVHPDGKLSVDQALVKQA---WDHVSARLLDWHIHLDKSLPGPLGS-IGAWLHRAEMALREDFPLHHAPEETANVLHRKLQQHQDVLKNLEVHRRTFQQIHKDRSVHGVPVPPEQLQDMAERFNFVS 459
BLAST of Nesprin-1 vs. Ensembl Medaka
Match: ENSORLT00000028699.1 (pep primary_assembly:ASM223467v1:24:9030419:9045840:-1 gene:ENSORLG00000028886.1 transcript:ENSORLT00000028699.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 207.223 bits (526), Expect = 1.185e-56 Identity = 165/446 (37.00%), Postives = 245/446 (54.93%), Query Frame = 2
Query: 194 EQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKK------IKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXX---------------------XXXALGMANDPNAKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNELDIVKDFNDKVDKNFENLNSKNN-----YDIFADLMSQ----RDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLM-EPFPNVHDKTFNDKVLQKLKEHESIFNKKNDVLAKFR 1420
EQE +QK+TFTKW+NS+L + PP+ +KDL +D+ DG++LL LLE+L+ L E+ K +++IH ++NI TAL+F+E K IKLVNIN +D+VDG+P+IVLGLVWT IL++QIEE + + P V+G A+K L+ W + L +KDFG SW G AF AL++ + P LV+ME + + +N+E L+ AF +AE ELGIP+LLD EDVDV+KPDEKS+MTYVAQFLK YP +K + + E+ S + + L +K + D+++++ Y +F L Q R ++ L D L +D V+Q +++ L +W LD+ LP L + +G WL +AE +L E + D + V + L++H+ L FR
Sbjct: 15 EQEAVQKRTFTKWINSHLAKHAPPLEVKDLFEDIKDGVMLLALLEVLSGQKLPCEQGKKLKRIHWVANIGTALKFLEGRKSAYRGSPIKLVNINSTDIVDGRPSIVLGLVWTIILYYQIEELTSSLPELPLLSSSTSSMDSSTSSTDTTSPPVKRKPLPPVQGGARKALLRWVQQTSTKCLRLEVKDFGPSWRTGLAFFALINALRPNLVDMERVRRRSNRENLQEAFLLAETELGIPQLLDPEDVDVDKPDEKSVMTYVAQFLK-YPPQRKQRDAQGQQQEEVTS-CQNCREQRKALRELKMWLDQLERDALQTQETGGSLAQQYQLFKSLHVQLEVRRKQVEGALQSTQRDGMLTVDQALVKQA---WERAS-NLLDWHLQLDRSLPAPLDT-VGVWLHEAEGALRDEMVVQLADDITANTVHRALEQHKVNGEAHEYFLPSFR 453
BLAST of Nesprin-1 vs. Ensembl Medaka
Match: ENSORLT00000033742.1 (pep primary_assembly:ASM223467v1:24:9030654:9050235:-1 gene:ENSORLG00000028886.1 transcript:ENSORLT00000033742.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 213.386 bits (542), Expect = 1.689e-56 Identity = 175/477 (36.69%), Postives = 258/477 (54.09%), Query Frame = 2
Query: 197 QEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXX---------------------XXXALGMANDPNAKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNELDIVKDFNDKVDKNFENLNSKNN-----YDIFADLMSQ----RDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLMEPFP----------NVHDKTFNDK-VLQKLKEHESIFNKKNDVLAKFREVLQNPPANISPKQLEAMKTRMENVCKA 1504
QE +QK+TFTKW+NS+L + PP+ +KDL +D+ DG++LL LLE+L+ L E+ K +++IH ++NI TAL+F+E +KIKLVNIN +D+VDG+P+IVLGLVWT IL++QIEE + + P V+G A+K L+ W + L +KDFG SW G AF AL++ + P LV+ME + + +N+E L+ AF +AE ELGIP+LLD EDVDV+KPDEKS+MTYVAQFLK YP +K + + E+ S + + L +K + D+++++ Y +F L Q R ++ L D L +D V+Q + L +W LD+ LP L + +G WL +AE +L + VH K VL+ L+ H+ IF + + K R V P + P QL+ M R+ V +
Sbjct: 19 QEAVQKRTFTKWINSHLAKHAPPLEVKDLFEDIKDGVMLLALLEVLSGQKLPCEQGKKLKRIHWVANIGTALKFLEG-RKIKLVNINSTDIVDGRPSIVLGLVWTIILYYQIEELTSSLPELPLLSSSTSSMDSSTSSTDTTSPPVKRKPLPPVQGGARKALLRWVQQTSTKCLRLEVKDFGPSWRTGLAFFALINALRPNLVDMERVRRRSNRENLQEAFLLAETELGIPQLLDPEDVDVDKPDEKSVMTYVAQFLK-YPPQRKQRDAQGQQQEEVTS-CQNCREQRKALRELKMWLDQLERDALQTQETGGSLAQQYQLFKSLHVQLEVRRKQVEGALQSTQRDGMLTVDQALVKQAW----ERASNLLDWHLQLDRSLPAPLDT-VGVWLHEAEGALRDEMVVQLADDITANTVHRALEQHKDVLRSLESHQQIFQR----IHKDRSVDGVP---VPPDQLQDMAERLNFVSTS 480
BLAST of Nesprin-1 vs. Ensembl Medaka
Match: ENSORLT00000031933.1 (pep primary_assembly:ASM223467v1:24:9030419:9050235:-1 gene:ENSORLG00000028886.1 transcript:ENSORLT00000031933.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 205.297 bits (521), Expect = 5.275e-56 Identity = 164/445 (36.85%), Postives = 242/445 (54.38%), Query Frame = 2
Query: 197 QEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKK------IKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXX---------------------XXXALGMANDPNAKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNELDIVKDFNDKVDKNFENLNSKNN-----YDIFADLMSQ----RDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLM-EPFPNVHDKTFNDKVLQKLKEHESIFNKKNDVLAKFR 1420
QE +QK+TFTKW+NS+L + PP+ +KDL +D+ DG++LL LLE+L+ L E+ K +++IH ++NI TAL+F+E K IKLVNIN +D+VDG+P+IVLGLVWT IL++QIEE + + P V+G A+K L+ W + L +KDFG SW G AF AL++ + P LV+ME + + +N+E L+ AF +AE ELGIP+LLD EDVDV+KPDEKS+MTYVAQFLK YP +K + + E+ S + + L +K + D+++++ Y +F L Q R ++ L D L +D V+Q + L +W LD+ LP L + +G WL +AE +L E + D + V + L++H+ L FR
Sbjct: 19 QEAVQKRTFTKWINSHLAKHAPPLEVKDLFEDIKDGVMLLALLEVLSGQKLPCEQGKKLKRIHWVANIGTALKFLEGRKSAYRGSPIKLVNINSTDIVDGRPSIVLGLVWTIILYYQIEELTSSLPELPLLSSSTSSMDSSTSSTDTTSPPVKRKPLPPVQGGARKALLRWVQQTSTKCLRLEVKDFGPSWRTGLAFFALINALRPNLVDMERVRRRSNRENLQEAFLLAETELGIPQLLDPEDVDVDKPDEKSVMTYVAQFLK-YPPQRKQRDAQGQQQEEVTS-CQNCREQRKALRELKMWLDQLERDALQTQETGGSLAQQYQLFKSLHVQLEVRRKQVEGALQSTQRDGMLTVDQALVKQAW----ERASNLLDWHLQLDRSLPAPLDT-VGVWLHEAEGALRDEMVVQLADDITANTVHRALEQHKVNGEAHEYFLPSFR 456
BLAST of Nesprin-1 vs. Ensembl Medaka
Match: ENSORLT00000037920.1 (pep primary_assembly:ASM223467v1:11:16926158:17021095:-1 gene:ENSORLG00000025786.1 transcript:ENSORLT00000037920.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 151.369 bits (381), Expect = 1.212e-36 Identity = 102/267 (38.20%), Postives = 150/267 (56.18%), Query Frame = 2
Query: 158 DTVVKKGVLLKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXXXXXALGMANDPNAKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITA 958
D + V + DE++++QKKTFTKW+N +L + + I + + + + + K + H L N++ AL+F++ +++KLVNI D+ DG P + LGL+WT ILHFQI E G + D AK K L+ W+ A GL +F SW DGR FNAL+H P L+NME + + +N++ LE AF IAE+ LG+ +LLD+EDVDV PDEKS++TYV+ ++P K PE E I+A
Sbjct: 64 DPAERAVVRVADERDRVQKKTFTKWVNKHLIKVRKHI----ADLYEDLRDGHNLISLLEVLSGVALPREKGRMRFHRLQNVQIALDFLKQ-RQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISEIYVS-----GESADLTAKEK------LLLWSQQATDGYPGLRCVNFTSSWSDGRMFNALLHRYRPDLINMEVVSQQSNRDNLEQAFEIAES-LGVTRLLDAEDVDVPSPDEKSVITYVSSIYDAFP--KIPEG-GEGISA 310
BLAST of Nesprin-1 vs. Planmine SMEST
Match: SMESG000077685.1 (SMESG000077685.1) HSP 1 Score: 6555.7 bits (17007), Expect = 0.000e+0 Identity = 3471/3576 (97.06%), Postives = 3514/3576 (98.27%), Query Frame = 2
Query: 3164 DWQDFKQTKDLMTKCFDDIIDDLKESHQKRKGVHGENLTDKADXXXXXXXXXXXXIKQEDXXXXXXXXXXXXXXEKPINEVKNLKDQILKQKANLEEEIQQNEKDLENHQQFNNDIQSLHDWLAQTELLTNQIQNLPNTKEGLIEKQKLLEDLNSLKSTGDKKLKELKNLQKVVLNETAPDEKENINIQLNAEIEKFNEVFVNLDKQGGINETIEKIEDLGEKSDQISENINEINKRLEKCLNLPSNTLNEKEKLAKELNNTIRLVDQQLAQINDLKSQCGSLEHSAALEDLLNKLESLEEHCFXXXXXXXXXXXXVDSDIKFQSALEEKLNDLSEIMNEVEIEFDYSKPKESSEAAINESLSQLQKLKAQHEPGKNILKTMIKLRNEFNAPEQCVTACNDLEQKYFDIEDDIKNLQKELEMKTTVWQKFNALKADLDKTCNTAILEIGNEHKKRSGIHGGDCEDKFNLLEDKKKILSNMTNKDPQVDALIEVSGKLGFDKALFDAQNIKRKYLKLIDDLQQEISQNEIDLDNHKKFDQSLFEFEDWMKNTEKIVKQIANLPNDKNGLLEKQNRLEEMKTLKSNGNEMIKNIKHLQNVVINETAGNFKTTLNEKVKNKIENFERVFGDLDQETDNIKETIDKLKVIDEKSXXXXXXXXXXXXXXXKCSIVPSESVGDKEKLGKIYRSLEHDIEQHLIDLDSLKQQCNALNATTANSAMINKLNKMTDECKSMKADISQLFSKNVSDLKNLKTFQDKMNEFNESMDRIETEIEKCSPNGCNEAAIKDNIKKLKKFRSLHENSKDVLTDLLRIGFELSGLSQISEASDQAEQKYSDVEDEITKLESKLEMQKNDWSNFNSDKNDLEKWLNEITKKVENLEQISDGIHGGKLSEKEKVLDSHQKLLQEALNREADIKLFLDRSTPLFSAVNQDSPKRVTNTLCKKYEKLLETLTNRIQKNEEDINLHENYAKQIDNFKEENNIIIKRMNEEIASLPNTKEGLKRKVDLLGNLKDLYNQRKMILVNLENLKNAVIDHSSSNYYSNLEQEWDQIIDSFEKSFNPSIENQSKLLLAVQQIEKTESICQDLQHQLENLERRLQEAVDQHISSLNDIDMKLETLKELRYELRDLQTPINDVQRKHCQNPSDVELIQERIEQIAKQHKVLNESISQNINETENHHKQLCNLTTSLNNFKTWLDYSSSQIEEKGKPGNLEMNNLKKNLTSLKQLADSISCQCDDQLSKIREHMLKIHKFSSEKLKDDLQKELNIMNGNVNSLKDKIQTTTEHEINRINEVEKIDILKNEIKENFLKFESQININFKNFDLNEKQNYITQLRNVQNLMKENEKKIEFLETSIQNIIKHSHGKMLDXXXXXXXXXXXXXXXQLNELINKLTQMSDEQMQFTDLLNDTKXXXXXXXXXXXXXXSFDNNIDQDKNNLNIVNEYLNINSKLSENKIEILRQKFKTVSRYVNEQENLKLEAEVDKLEKKFHETIELSKDNQSALLLNINNVTEADLFYERTIKWLNSKVSELEQFYVKPETLREKENRLRILNKIKFETEENTSMIKRQMDNLPVLLTVQNKNVDNKINTLKIQLKEIFERVSEEFNIHEEFSENFHSLINNMESCKYQLIQCVESIEFDXXXXXXXXXXXXXFTENISNNNKQLNKVNELYQTVKYQTSPGGIAILDTEMQLAQTLSKDIDELFLKLKTKEQKFENLQNKFESLINSIENSLTENEDEMKKLSELKRDLKQKASTKQHLVENILPEIHGTQSLIDELKEVCYEYLSEIIDRNKSRRANDIFYRFSELSRLAESSIKKVQKACEDHELFDKFYKEAVEYFNEINDEIEFVSNLLDVETNTFHELTKLTAKLSSYETQRTEFFQSMHNVESQGQITMELSNKEGRDLVRRQIKEINEHCNKLVDKINSTKIKLDRNIDNYNATKEKLDKINEFTNEINDRLNIIKSEVRDFNEKNQSIIWLGNCKDECDSNLKNLKLIKSSSVFPDLNXXXXXXXXXXXXXXXXXXDLTSNLKTELRRINEFENEKLTINKWLESLEKQYETLITSFSISDNLDLKINLIKNFETTSIDQVKISKFEEIQNQLQIQKTIVTNLMYMNQEFEVKDQIKKVNLFHEMIKRSIAIFEETSXXXXXXXXXXXXXXXXXXXAKSILQTKQNSEHNLKELKINVENLFEEFSKLNGEIDIEKFVITSVLSSENVEPXXXXXXXXXXXXXQLKSEMEIISKDIERRLKQIQIEEEIQNKFLENSERFYLFANEINVNIDEFDLQSINNFNQIDTITNKIIEIQKLFENIKETSVKQINQTKDLQIENEVKLARKKLSELNEKYENLFQVVQEKVKQVDAFSKLETDLENWLKYADNYMERYSENKPYSTHLQCETNLENMKEFFHEFEDKEYLLDKLKQMHCANNFPYIEKIEILTESFKKLKTEIENQINHLNKKTSGVLEMAESMESFNQYLRQDYLEYEKLEEIFNKCKNQFNQTAMNKLRLCLNDNAFSIRQETLWNLLQNVRKFSKLVERSRIDIAGNLLDQKETAENELETLKANWSKLSKRINELNNLKMDLDKALEHFNIWLNNSCKWFVNITETRKKVFESNETLQMKNNLQALKDDITEHKVDLSRLQTFVDSLMKICNDETFQKTLDEITKEYNVLFNKCQNECDKCDHLIKLMTKYEISRADVLHWIEASTQTLLKCSDYTLKQSQMKSKLLMIDNLEKELENYGQSKFVEAIQDGEELLGELAGMPMQIVQQQMADLKSDWMEISRQLNQLSSNLRNTTSRSEAFKEMSNRLSNWLDDIEHTGLMDLSHIEHQCEIPFESGNSSSKHDRAKTLLTELNRHKQDFLQLANLATELANPSFDIENSQIQNRYIRLSNNLKDKIEKLNKQQADYDQIKQDIEEMEKWVFQTSIRIINENAEQGKTTNNTIQEIETLIKHSNEIIANILSQEPEIVKIGQAVDSLINISNNKNSDKEKELQDDLSKLIENFNNLKSSSIHKRDHLKDSVKKWDTYQDFLQSTKLFLDNELPNWWRERNQDQMKSAYSNFNNEPILKEILDMDNKLNGLKTTMELEAKACDGILPTIAITASRSQTPNFKSNRSLYSPSSNWSTNKSDVTPNDELIPNILSKSIYEDLDENIKKVSNLKKEIIEKITDWNNFNREKTSFKNWMDNEMLKFSSVLYTEPGISNFASLQKSKLKEIQEEMNYKKQALLNLNTHFKELTSNVSGAADLVLKNLNQDFDETEKKISKLLNREDKGVEADFTDEESNMDIIQERKVPKLNLKNLESPQLFRYESPENLNRFTQTNISKDETDYKFKKTNFSSQTPGTKTTQTNFNDMSNFGTQTNDKYQKKRERKLESELQILNSLKNMNSEFERSKPFPEYNNISSVPMSAKPRSSALESVRRNIYPSYSQTRQTTCSPLMQRIENGYKSRRPLSPSTHSQNLLNKPLSQNSNLNLTKSSGDNLDDLIPTKNKWVDLEINAQLINSSLKSYPFDVPSREFHIDYNTKFEGFPVSLRKKSPQRRSSGXXXXXXXXXXXXXXITDSINRITEDANELRNLSQKLRSVK 13891
+W + K + K + + DD+ SH+ RKG+HG++ DK + +NK+RL++L +E + +L + A LG EKP+NEV LK L+ K +LE EI+ NEKDL+NH+Q+ ND+ HDW+ + E L ++I P+TK GLIEKQ LL L +LK G+K LKE+KNLQKVVLNETAPDEKENINIQLNAEIEKFNEVFVNLD Q GINETIEKIEDLGE+SDQ+SE+I+EINK+LEKCLNLPSNTLNEKEKLAKELN+T RL+DQQLA+INDLKSQCGSLEHSAALEDLLNKLESLEEHCFEIKTKIEERIKEVDSDIKFQSALEEKLNDLSEIMNEVEIEFDYSKPKESSEAAINESLSQLQKLKAQHEPGKNILKTMIKLRNEFNAPEQCVTACNDLEQKYFDIEDDIKNLQKELEMKTTVWQKFNALKADLDKTCNTAILEIGNEHKKRSGIHGGDCEDKFNLLEDKKKILSNMTNKDPQVDALIEVSGKLGFDKALFDAQNIKRKYLKLIDDLQQEISQNEIDLDNHKKFDQSLFEFEDWMKNTEKIVKQIANLPNDKNGLLEKQNRLEEMKTLKSNGNEMIKNIKHLQNVVINETAGNFKTTLNEKVKNKIENFERVFGDLDQETDNIKETIDKLKVIDEKSNEMERNIREIENTINKCSIVPSESVGDKEKLGKIYRSLEHDIEQHLIDLDSLKQQCNALNATTANSAMINKLNKMTDECKSMKADISQLFSKNVSDLKNLKTFQDKMNEFNESMDRIETEIEKCSPNGCNEAAIKDNIKKLKKFRSLHENSKDVLTDLLRIGFELSGLSQISEASDQAEQKYSDVEDEITKLESKLEMQKNDWSNFNSDKNDLEKWLNEITKKVENLEQISDGIHGGKLSEKEKVLDSHQKLLQEALNREADIKLFLDRSTPLFSAVNQDSPKRVTNTLCKKYEKLLETLTNRIQKNEEDINLHENYAKQIDNFKEENNIIIKRMNEEIASLPNTKEGLKRKVDLLGNLKDLYNQRKMILVNLENLKNAVIDHSSSNYYSNLEQEWDQIIDSFEKSFNPSIENQSKLLLAVQQIEKTESICQDLQHQLENLERRLQEAVDQHISSLNDIDMKLETLKELRYELRDLQTPINDVQRKHCQNPSDVELIQERIEQIAKQHKVLNESISQNINETENHHKQLCNLTTSLNNFKTWLDYSSSQIEEKGKPGNLEMNNLKKNLTSLKQLADSISCQCDDQLSKIREHMLKIHKFSSEKLKDDLQKELNIMNGNVNSLKDKIQTTTEHEINRINEVEKIDILKNEIKENFLKFESQININFKNFDLNEKQNYITQLRNVQNLMKENEKKIEFLETSIQNIIKHSHGKMLDINANKIINKRNSIKIQLNELINKLTQMSDEQMQFTDLLNDTKICIENQHNEINIEISFDNNIDQDKNNLNIVNEYLNINSKLSENKIEILRQKFKTVSRYVNEQENLKLEAEVDKLEKKFHETIELSKDNQSALLLNINNVTEADLFYERTIKWLNSKVSELEQFYVKPETLREKENRLRILNKIKFETEENTSMIKRQMDNLPVLLTVQNKNVDNKINTLKIQLKEIFERVSEEFNIHEEFSENFHSLINNMESCKYQLIQCVESIEFDKENKIIKKNSEEIFTENISNNNKQLNKVNELYQTVKYQTSPGGIAILDTEMQLAQTLSKDIDELFLKLKTKEQKFENLQNKFESLINSIENSLTENEDEMKKLSELKRDLKQKASTKQHLVENILPEIHGTQSLIDELKEVCYEYLSEIIDRNKSRRANDIFYRFSELSRLAESSIKKVQKACEDHELFDKFYKEAVEYFNEINDEIEFVSNLLDVETNTFHELTKLTAKLSSYETQRTEFFQSMHNVESQGQITMELSNKEGRDLVRRQIKEINEHCNKLVDKINSTKIKLDRNIDNYNATKEKLDKINEFTNEINDRLNIIKSEVRDFNEKNQSIIWLGNCKDECDSNLKNLKLIKSSSVFPDLNKGIETIELKLEKLNKKIKDLTSNLKTELRRINEFENEKLTINKWLESLEKQYETLITSFSISDNLDLKINLIKNFETTSIDQVKISKFEEIQNQLQIQKTIVTNLMYMNQEFEVKDQIKKVNLFHEMIKRSIAIFEETSTKINENKTIINKIEKWIINAKSILQTKQNSEHNLKELKINVENLFEEFSKLNGEIDIEKFVITSVLSSENVEPFFNILSNNLSNINQLKSEMEIISKDIERRLKQIQIEEEIQNKFLENSERFYLFANEINVNIDEFDLQSINNFNQIDTITNKIIEIQKLFENIKETSVKQINQTKDLQIENEVKLARKKLSELNEKYENLFQVVQEKVKQVDAFSKLETDLENWLKYADNYMERYSENKPYSTHLQCETNLENMKEFFHEFEDKEYLLDKLKQMHCANNFPYIEKIEILTESFKKLKTEIENQINHLNKKTSGVLEMAESMESFNQYLRQDYLEYEKLEEIFNKCKNQFNQTAMNKLRLCLNDNAFSIRQETLWNLLQNVRKFSKLVERSRIDIAGNLLDQKETAENELETLKANWSKLSKRINELNNLKMDLDKALEHFNIWLNNSCKWFVNITETRKKVFESNETLQMKNNLQALKDDITEHKVDLSRLQTFVDSLMKICNDETFQKTLDEITKEYNVLFNKCQNECDKCDHLIKLMTKYEISRADVLHWIEASTQTLLKCSDYTLKQSQMKSKLLMIDNLEKELENYGQSKFVEAIQDGEELLGELAGMPMQIVQQQMADLKSDWMEISRQLNQLSSNLRNTTSRSEAFKEMSNRLSNWLDDIEHTGLMDLSHIEHQCEIPFESGNSSSKHDRAKTLLTELNRHKQDFLQLANLATELANPSFDIENSQIQNRYIRLSNNLKDKIEKLNKQQADYDQIKQDIEEMEKWVFQTSIRIINENAEQGKTTNNTIQEIETLIKHSNEIIANILSQEPEIVKIGQAVDSLINISNNKNSDKEKELQDDLSKLIENFNNLKSSSIHKRDHLKDSVKKWDTYQDFLQSTKLFLDNELPNWWRERNQDQMKSAYSNFNNEPILKEILDMDNKLNGLKTTMELEAKACDGILPTIAITASRSQTPNFKSNRSLYSPSSNWSTNKSDVTPNDELIPNILSKSIYEDLDENIKKVSNLKKEIIEKITDWNNFNREKTSFKNWMDNEMLKFSSVLYTEPGISNFASLQKSKLKEIQEEMNYKKQALLNLNTHFKELTSNVSGAADLVLKNLNQDFDETEKKISKLLNREDKGVEADFTDEESNMDIIQERKVPKLNLKNLESPQLFRYESPENLNRFTQTNISKDETDYKFKKTNFSSQTPGTKTTQTNFNDMSNFGTQTNDKYQKKRERKLESELQILNSLKNMNSEFERSKPFPEYNNISSVPMSAKPRSSALESVRRNIYPSYSQTRQTTCSPLMQRIENGYKSRRPLSPSTHSQNLLNKPLSQNSNLNLTKSSGDNLDDLIPTKNKWVDLEINAQLINSSLKSYPFDVPSREFHIDYNTKFEGFPVSLRKKSPQRRSSGSPKRNRSKSARNSRITDSINRITEDANELRNLSQKLRSVK
Sbjct: 1856 NWSRYNLIKSDIEKSLETLKDDINVSHEMRKGIHGKDSKDKETIFHDNKKRLQDLNDKEKVINELIEMAKLLGSEKPVNEVLQLKKTFLEDKDDLENEIKINEKDLKNHRQYENDLDLFHDWILEAESLADKISGTPSTKAGLIEKQNLLNKLKNLKPVGEKMLKEIKNLQKVVLNETAPDEKENINIQLNAEIEKFNEVFVNLDIQDGINETIEKIEDLGEQSDQVSEDISEINKKLEKCLNLPSNTLNEKEKLAKELNSTNRLLDQQLAKINDLKSQCGSLEHSAALEDLLNKLESLEEHCFEIKTKIEERIKEVDSDIKFQSALEEKLNDLSEIMNEVEIEFDYSKPKESSEAAINESLSQLQKLKAQHEPGKNILKTMIKLRNEFNAPEQCVTACNDLEQKYFDIEDDIKNLQKELEMKTTVWQKFNALKADLDKTCNTAILEIGNEHKKRSGIHGGDCEDKFNLLEDKKKILSNMTNKDPQVDALIEVSGKLGFDKALFDAQNIKRKYLKLIDDLQQEISQNEIDLDNHKKFDQSLFEFEDWMKNTEKIVKQIANLPNDKNGLLEKQNRLEEMKTLKSNGNEMIKNIKHLQNVVINETAGNFKTTLNEKVKNKIENFERVFGDLDQETDNIKETIDKLKVIDEKSNEMERNIREIENTINKCSIVPSESVGDKEKLGKIYRSLEHDIEQHLIDLDSLKQQCNALNATTANSAMINKLNKMTDECKSMKADISQLFSKNVSDLKNLKTFQDKMNEFNESMDRIETEIEKCSPNGCNEAAIKDNIKKLKKFRSLHENSKDVLTDLLRIGFELSGLSQISEASDQAEQKYSDVEDEITKLESKLEMQKNDWSNFNSDKNDLEKWLNEITKKVENLEQISDGIHGGKLSEKEKVLDSHQKLLQEALNREADIKLFLDRSTPLFSAVNQDSPKRVTNTLCKKYEKLLETLTNRIQKNEEDINLHENYAKQIDNFKEENNIIIKRMNEEIASLPNTKEGLKRKVDLLGNLKDLYNQRKMILVNLENLKNAVIDHSSSNYYSNLEQEWDQIIDSFEKSFNPSIENQSKLLLAVQQIEKTESICQDLQHQLENLERRLQEAVDQHISSLNDIDMKLETLKELRYELRDLQTPINDVQRKHCQNPSDVELIQERIEQIAKQHKVLNESISQNINETENHHKQLCNLTTSLNNFKTWLDYSSSQIEEKGKPGNLEMNNLKKNLTSLKQLADSISCQCDDQLSKIREHMLKIHKFSSEKLKDDLQKELNIMNGNVNSLKDKIQTTTEHEINRINEVEKIDILKNEIKENFLKFESQININFKNFDLNEKQNYITQLRNVQNLMKENEKKIEFLETSIQNIIKHSHGKMLDINANKIINKRNSIKIQLNELINKLTQMSDEQMQFTDLLNDTKICIENQHNEINIEISFDNNIDQDKNNLNIVNEYLNINSKLSENKIEILRQKFKTVSRYVNEQENLKLEAEVDKLEKKFHETIELSKDNQSALLLNINNVTEADLFYERTIKWLNSKVSELEQFYVKPETLREKENRLRILNKIKFETEENTSMIKRQMDNLPVLLTVQNKNVDNKINTLKIQLKEIFERVSEEFNIHEEFSENFHSLINNMESCKYQLIQCVESIEFDKENKIIKKNSEEIFTENISNNNKQLNKVNELYQTVKYQTSPGGIAILDTEMQLAQTLSKDIDELFLKLKTKEQKFENLQNKFESLINSIENSLTENEDEMKKLSELKRDLKQKASTKQHLVENILPEIHGTQSLIDELKEVCYEYLSEIIDRNKSRRANDIFYRFSELSRLAESSIKKVQKACEDHELFDKFYKEAVEYFNEINDEIEFVSNLLDVETNTFHELTKLTAKLSSYETQRTEFFQSMHNVESQGQITMELSNKEGRDLVRRQIKEINEHCNKLVDKINSTKIKLDRNIDNYNATKEKLDKINEFTNEINDRLNIIKSEVRDFNEKNQSIIWLGNCKDECDSNLKNLKLIKSSSVFPDLNKGIETIELKLEKLNKKIKDLTSNLKTELRRINEFENEKLTINKWLESLEKQYETLITSFSISDNLDLKINLIKNFETTSIDQVKISKFEEIQNQLQIQKTIVTNLMYMNQEFEVKDQIKKVNLFHEMIKRSIAIFEETSTKINENKTIINKIEKWIINAKSILQTKQNSEHNLKELKINVENLFEEFSKLNGEIDIEKFVITSVLSSENVEPFFNILSNNLSNINQLKSEMEIISKDIERRLKQIQIEEEIQNKFLENSERFYLFANEINVNIDEFDLQSINNFNQIDTITNKIIEIQKLFENIKETSVKQINQTKDLQIENEVKLARKKLSELNEKYENLFQVVQEKVKQVDAFSKLETDLENWLKYADNYMERYSENKPYSTHLQCETNLENMKEFFHEFEDKEYLLDKLKQMHCANNFPYIEKIEILTESFKKLKTEIENQINHLNKKTSGVLEMAESMESFNQYLRQDYLEYEKLEEIFNKCKNQFNQTAMNKLRLCLNDNAFSIRQETLWNLLQNVRKFSKLVERSRIDIAGNLLDQKETAENELETLKANWSKLSKRINELNNLKMDLDKALEHFNIWLNNSCKWFVNITETRKKVFESNETLQMKNNLQALKDDITEHKVDLSRLQTFVDSLMKICNDETFQKTLDEITKEYNVLFNKCQNECDKCDHLIKLMTKYEISRADVLHWIEASTQTLLKCSDYTLKQSQMKSKLLMIDNLEKELENYGQSKFVEAIQDGEELLGELAGMPMQIVQQQMADLKSDWMEISRQLNQLSSNLRNTTSRSEAFKEMSNRLSNWLDDIEHTGLMDLSHIEHQCEIPFESGNSSSKHDRAKTLLTELNRHKQDFLQLANLATELANPSFDIENSQIQNRYIRLSNNLKDKIEKLNKQQADYDQIKQDIEEMEKWVFQTSIRIINENAEQGKTTNNTIQEIETLIKHSNEIIANILSQEPEIVKIGQAVDSLINISNNKNSDKEKELQDDLSKLIENFNNLKSSSIHKRDHLKDSVKKWDTYQDFLQSTKLFLDNELPNWWRERNQDQMKSAYSNFNNEPILKEILDMDNKLNGLKTTMELEAKACDGILPTIAITASRSQTPNFKSNRSLYSPSSNWSTNKSDVTPNDELIPNILSKSIYEDLDENIKKVSNLKKEIIEKITDWNNFNREKTSFKNWMDNEMLKFSSVLYTEPGISNFASLQKSKLKEIQEEMNYKKQALLNLNTHFKELTSNVSGAADLVLKNLNQDFDETEKKISKLLNREDKGVEADFTDEESNMDIIQERKVPKLNLKNLESPQLFRYESPENLNRFTQTNISKDETDYKFKKTNFSSQTPGTKTTQTNFNDMSNFGTQTNDKYQKKRERKLESELQILNSLKNMNSEFERSKPFPEYNNISSVPMSAKPRSSALESVRRNIYPSYSQTRQTTCSPLMQRIENGYKSRRPLSPSTHSQNLLNKPLSQNSNLNLTKSSGDNLDDLIPTKNKWVDLEINAQLINSSLKSYPFDVPSREFHIDYNTKFEGFPVSLRKKSPQRRSSGSPKRNRSKSARNSRITDSINRITEDANELRNLSQKLRSVK 5431 HSP 2 Score: 2623.58 bits (6799), Expect = 0.000e+0 Identity = 1552/2065 (75.16%), Postives = 1748/2065 (84.65%), Query Frame = 2
Query: 146 MDRKDTVVKKGVLLKDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXXXXXALGMANDPNAKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNELDIVKDFNDKVDKNFENLNSKNNYDIFADLMSQRDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLMEPFPNVHDKTFNDKVLQKLKEHESIFNKKNDVLAKFREVLQNPPANISPKQLEAMKTRMENVCKAEGPVREKLNIFGIQANLKNKAQKWAVDLNSWDSPIQSKQDLLDKIEQFNISMENGTSMDKFTSQLDELVKRKVKFCKENPVLDEDLLNFINKAINECEEENDILPEKFESTLMKLENLSSEWDEISDGEQKIETFSRRLSKALQLDDFQQQRSLVDQLPEVLDLLNDVKYKIQNDLTPHCSEKLLYTMXXXXXXXXXXXXXXGAXXXXXXXXXXXXXXXXXXAARDTLIDEIFSCGQANVDSIKQWMNDLDQCMETPINGSSADLQYVLSKLKDLDKESPKIQKLIDQGYQKVDDLENENSPEKAQELKESLNEFQKKFKRYTEKEIPKNLQNLKTFIDTLNIVENDINDLEKTMKEGEFIKNHLDDLEFSNGTDDIIFKEQEFLEKENEXXXXXXXXXXXXXXXXXXVESTDLKIDLKPLEKRIFDSENVLQDLLTNAKENLTANNQCNEACTSADQSLECLLDQIEKNSSINNDEEGQKTKLKNIQNFXXXXXXXXKQINAAVAXXXXXXXXXXXXXXDKIDNSISKIKQKTVSIKENLQKTKVNLSNNLNDWQDFKQTKDLMTKCFDDIIDDLKESHQKRKGVHGENLTDKADXXXXXXXXXXXXIKQEDXXXXXXXXXXXXXXEKPINEVKNLKDQILKQKANLEEEIQQNEKDLENHQQFNNDIQSLHDWLAQTELLTNQIQNLPNTKEGLIEKQKLLEDLNSLKSTGDKKLKELKNLQKVVLNETAPDEKENINIQLNAEIEKFNEVFVNLDKQGGINETIEKIEDLGEKSDQISENINEINKRLEKCLNLPSNTLNEKEKLAKELNNTIRLVDQQLAQINDLKSQCGSLEHSAALEDLLNKLESLEEHCFXXXXXXXXXXXXVDSDIKFQSALEEKLNDLSEIMNEVEIEFDYSKPKESSEAAINESLSQLQKLKAQHEPGKNILKTMIKLRNEFNAPEQCVTACNDLEQKYFDIEDDIKNLQKELEMKTTVWQKFNALKADLDKTCNTAILEIGNEHKKRSGIHGGDCEDKFNLLEDKKKILSNMTNKDPQVDALIEVSGKLGFDKALFDAQNIKRKYLKLIDDLQQEISQNEIDLDNHKKFDQSLFEFEDWMKNTEKIVKQIANLPNDKNGLLEKQNRLEEMKTLKSNGNEMIKNIKHLQNVVINETAGNFKTTLNEKVKNKIENFERVFGDLDQETDNIKETIDKLKVIDEKSXXXXXXXXXXXXXXXKCSIVPSESVGDKEKLGKIYRSLEHDIEQHLIDLDSLKQQCNALNATTANSAMINKLNKMTDECKSMKADISQLFSKNVSDLKNLKTFQDKMNEFNESMDRIETEIEKCSPNGCNEAAIKDNIKKLKKFRSLHENSKDVLTDLLRIGFELSGLSQISEASDQAEQKYSDVEDEITKLESKLEMQKNDWSNFNSDKNDLEKWLNEITKKVENLEQISDGIHGGKLSEKEKVLDSHQKLLQEALNREADIKLFLDRSTPLFSAVNQDSPKRVTNTLCKKYEKLLETLTNRIQKNEEDINLHENYAKQIDNFKEENNIII--KRMNEEIASLPNTKEGLKRKVDLLGNLKDLYNQRKMILVNLENLKNAVIDHSSSNYYSNLEQEWDQIIDSFEKSF 6334
MDRKDTVVKKGVLLKDEQEKMQKKTFTKWMNSYLCQKKPPIIIKDLMKDLSDGLLLLDLLEILTKTTLKKEKPKNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAILHFQIEEQEEFLLQALGMANDPNAKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNELDIVKDFNDKVDKNFENLNSKNNYDIFADLMSQRDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLMEPFPNVHDKTFNDKVLQKLKEHESIFNKKNDVLAKFREVLQNPPANISPKQLEAMKTRMENVCKAEGPVREKLNIFGIQANLKNKAQKWAVDLNSWDSPIQSKQDLLDKIEQFNISMENGTSMDKFTSQLDELVKRKVKFCKENPVLDEDLLNFINKAINECEEENDILPEKFESTLMKLENLSSEWDEISDGEQKIETFSRRLSKALQLDDFQQQRSLVDQLPEVLDLLNDVKYKIQNDLTPHCSEKLLYTMKENLNELEINLKELGAQVVDKVEKQKQKIEQQQQAARDTLIDEIFSCGQANVDSIKQWMNDLDQCMETPINGSSADLQYVLSKLKDLDKESPKIQKLIDQGYQKVDDLENENSPEKAQELKESLNEFQKKFKRYTEKEIPKNLQNLKTFIDTLNIVENDINDLEKTMKEGEFIKNHLDDLEFSNGTDDIIFKEQEFLEKENEISKSLIKDKDLLKHIKKLVESTDLKIDLKPLEKRIFDSENVLQDLLTNAKENLTANNQCNEACTSADQSLECLLDQIEKNSSINNDEEGQKTKLKNIQNFEEEIEEVEKQINAAVALRNNLLSNLNKSNLDKIDNSISKIKQKTVSIKENLQKTKVNLSNNLNDWQDFKQTKDLMTKCFDDIIDDLKESHQKRKGVHGENLTDKADLLEENKERLENLIKQEDKLKDLNKKALKLGLEKPINEVKNLKDQILKQKANLEEEIQQNEKDLENHQQFNNDIQSLHDWLAQTELLTNQIQNLPNTKEGLIEKQKLLEDLNSLKSTGDKKLKELKNLQKVVLNETAPDEKENINIQLNAEIEKFNEVFVNLDKQGGINETIEKIEDLGEKSDQISENINEINKRLEKCLNLPSNTLNEKEKLAKELNNTIRLVDQQLAQINDLKSQC LE+ A+E+LLN LESLEE C K KIEE++ E +SDIK Q ALE L L+++MNE E E S K++ +A+ E+L +L+ LK++ E KNIL+ + + +++FN P+ C+ AC ++KY D++D+I L++ L + W +F++ K+ ++++ T +I N H +GIHGGDC+DK +LL +KK L ++ ++ + + L + KLG + + + QN+K + LK ++L++EI QNE DL+NH++F+ + DW+ TE + QI NLPN K GL+EKQ LE++ +LKS G++ +K +K+LQ VV+NETA + K +N ++ +IE F VF +LD++ I ETI+K++ + EKS+++ NI EI + KC +PS ++ +KEKL K + ++Q L ++ LK QC +L A +++KL + ++C K++I +N ++K F++K++EF M+ E EI P +E AI+++++KL+ +S H K+ L ++L+ EL + SE ++ E+KY ++E+ I L + LE +K++WS +N K+D+EK L + + ++ GIHG +KE + ++K LQ+ ++E I ++ + L S + P L K + + + L N I+ NE+D+ H Y +D F ++ I+ + + ++I+ P+TK GL K +LL LK+L + +L ++NL+ V++ ++ + N+ + + I+ F + F
Sbjct: 1 MDRKDTVVKKGVLLKDEQEKMQKKTFTKWMNSYLCQKKPPIIIKDLMKDLSDGLLLLDLLEILTKTTLKKEKPKNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAILHFQIEEQEEFLLQALGMANDPNAKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNELDIVKDFNDKVDKNFENLNSKNNYDIFADLMSQRDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLMEPFPNVHDKTFNDKVLQKLKEHESIFNKKNDVLAKFREVLQNPPANISPKQLEAMKTRMENVCKAEGPVREKLNIFGIQANLKNKAQKWAVDLNSWDSPIQSKQDLLDKIEQFNISMENGTSMDKFTSQLDELVKRKVKFCKENPVLDEDLLNFINKAINECEEENDILPEKFESTLMKLENLSSEWDEISDGEQKIETFSRRLSKALQLDDFQQQRSLVDQLPEVLDLLNDVKYKIQNDLTPHCSEKLLYTMKENLNELEINLKELGAQVVDKVEKQKQKIEQQQQAARDTLIDEIFSCGQANVDSIKQWMNDLDQCMETPINGSSADLQYVLSKLKDLDKESPKIQKLIDQGYQKVDDLENENSPEKAQELKESLNEFQKKFKRYTEKEIPKNLQNLKTFIDTLNIVENDINDLEKTMKEGEFIKNHLDDLEFSNGTDDIIFKEQEFLEKENEISKSLIKDKDLLKHIKKLVESTDLKIDLKPLEKRIFDSENVLQDLLTNAKENLTANNQCNEACTSADQSLECLLDQIEKNSSINNDEEGQKTKLKNIQNFEEEIEEVEKQINAAVALRNNLLSNLNKSNLDKIDNSISKIKQKTVSIKENLQKTKVNLSNNLNDWQDFKQTKDLMTKCFDDIIDDLKESHQKRKGVHGENLTDKADLLEENKERLENLIKQEDKLKDLNKKALKLGLEKPINEVKNLKDQILKQKANLEEEIQQNEKDLENHQQFNNDIQSLHDWLAQTELLTNQIQNLPNTKEGLIEKQKLLEDLNSLKSTGDKKLKELKNLQKVVLNETAPDEKENINIQLNAEIEKFNEVFVNLDKQGGINETIEKIEDLGEKSDQISENINEINKRLEKCLNLPSNTLNEKEKLAKELNNTIRLVDQQLAQINDLKSQCKHLENCEAVEELLNNLESLEEQCNIRKAKIEEKMNETESDIKKQVALENNLKILADLMNETETEMKISVTKQTGASAVEENLEKLKGLKSKLESEKNILENIEEQKDDFNVPKHCLMACKSSKKKYLDLKDEIHQLEENLNLMKNNWSEFDSAKSKIEESLETIGNDIENMHVTHNGIHGGDCDDKVSLLNEKKNELDDLIRQEEETNDLFSKAKKLGSNAPMIEIQNLKERILKQKENLKKEIKQNEKDLENHQQFNNDIQSLHDWLAQTELLTNQIQNLPNTKEGLIEKQKLLEDLNSLKSTGDKKLKELKNLQKVVLNETAPDEKENINIQLNAEIEKFNEVFVNLDKQG-GINETIEKIEDLGEKSDQISENINEINKRLEKCLNLPSNTLNEKEKLAKELNNTIRLVDQQLAQINDLKSQCESLENCEAVEELLDKLESLEEQCNENKSEIEDKIVENNINIKMQAAFEEKLDEFANLMNEAEIEITSL-PKENSEIAIEESLQKLENIKSKHLPGKNTLEEILKSQTELRIPQEYSETCEKYEEKYCNLENGIKDLTNALEQKKSNWSRYNLIKSDIEKSLETLKDDINVSHEMRKGIHGKDSKDKETIFHDNKKRLQDLNDKEKVINELIEMAKLLGS----EKPVNEVLQLKKTFLEDKDDLENEIKINEKDLKNHRQYENDLDLF---HDWILEAESLADKISGTPSTKAGLIEKQNLLNKLKNLKPVGEKMLKEIKNLQKVVLNETAPDEKENINIQLNAEIEKFNEVF 2056
BLAST of Nesprin-1 vs. Planmine SMEST
Match: SMESG000077685.1 (SMESG000077685.1) HSP 1 Score: 6555.31 bits (17006), Expect = 0.000e+0 Identity = 3476/3594 (96.72%), Postives = 3523/3594 (98.02%), Query Frame = 2
Query: 3122 NLQKTKVNLSNNL----NDWQDFKQTKDLMTKCFDDIIDDLKESHQKRKGVHGENLTDKADXXXXXXXXXXXXIKQEDXXXXXXXXXXXXXXEKPINEVKNLKDQILKQKANLEEEIQQNEKDLENHQQFNNDIQSLHDWLAQTELLTNQIQNLPNTKEGLIEKQKLLEDLNSLKSTGDKKLKELKNLQKVVLNETAPDEKENINIQLNAEIEKFNEVFVNLDKQGGINETIEKIEDLGEKSDQISENINEINKRLEKCLNLPSNTLNEKEKLAKELNNTIRLVDQQLAQINDLKSQCGSLEHSAALEDLLNKLESLEEHCFXXXXXXXXXXXXVDSDIKFQSALEEKLNDLSEIMNEVEIEFDYSKPKESSEAAINESLSQLQKLKAQHEPGKNILKTMIKLRNEFNAPEQCVTACNDLEQKYFDIEDDIKNLQKELEMKTTVWQKFNALKADLDKTCNTAILEIGNEHKKRSGIHGGDCEDKFNLLEDKKKILSNMTNKDPQVDALIEVSGKLGFDKALFDAQNIKRKYLKLIDDLQQEISQNEIDLDNHKKFDQSLFEFEDWMKNTEKIVKQIANLPNDKNGLLEKQNRLEEMKTLKSNGNEMIKNIKHLQNVVINETAGNFKTTLNEKVKNKIENFERVFGDLDQETDNIKETIDKLKVIDEKSXXXXXXXXXXXXXXXKCSIVPSESVGDKEKLGKIYRSLEHDIEQHLIDLDSLKQQCNALNATTANSAMINKLNKMTDECKSMKADISQLFSKNVSDLKNLKTFQDKMNEFNESMDRIETEIEKCSPNGCNEAAIKDNIKKLKKFRSLHENSKDVLTDLLRIGFELSGLSQISEASDQAEQKYSDVEDEITKLESKLEMQKNDWSNFNSDKNDLEKWLNEITKKVENLEQISDGIHGGKLSEKEKVLDSHQKLLQEALNREADIKLFLDRSTPLFSAVNQDSPKRVTNTLCKKYEKLLETLTNRIQKNEEDINLHENYAKQIDNFKEENNIIIKRMNEEIASLPNTKEGLKRKVDLLGNLKDLYNQRKMILVNLENLKNAVIDHSSSNYYSNLEQEWDQIIDSFEKSFNPSIENQSKLLLAVQQIEKTESICQDLQHQLENLERRLQEAVDQHISSLNDIDMKLETLKELRYELRDLQTPINDVQRKHCQNPSDVELIQERIEQIAKQHKVLNESISQNINETENHHKQLCNLTTSLNNFKTWLDYSSSQIEEKGKPGNLEMNNLKKNLTSLKQLADSISCQCDDQLSKIREHMLKIHKFSSEKLKDDLQKELNIMNGNVNSLKDKIQTTTEHEINRINEVEKIDILKNEIKENFLKFESQININFKNFDLNEKQNYITQLRNVQNLMKENEKKIEFLETSIQNIIKHSHGKMLDXXXXXXXXXXXXXXXQLNELINKLTQMSDEQMQFTDLLNDTKXXXXXXXXXXXXXXSFDNNIDQDKNNLNIVNEYLNINSKLSENKIEILRQKFKTVSRYVNEQENLKLEAEVDKLEKKFHETIELSKDNQSALLLNINNVTEADLFYERTIKWLNSKVSELEQFYVKPETLREKENRLRILNKIKFETEENTSMIKRQMDNLPVLLTVQNKNVDNKINTLKIQLKEIFERVSEEFNIHEEFSENFHSLINNMESCKYQLIQCVESIEFDXXXXXXXXXXXXXFTENISNNNKQLNKVNELYQTVKYQTSPGGIAILDTEMQLAQTLSKDIDELFLKLKTKEQKFENLQNKFESLINSIENSLTENEDEMKKLSELKRDLKQKASTKQHLVENILPEIHGTQSLIDELKEVCYEYLSEIIDRNKSRRANDIFYRFSELSRLAESSIKKVQKACEDHELFDKFYKEAVEYFNEINDEIEFVSNLLDVETNTFHELTKLTAKLSSYETQRTEFFQSMHNVESQGQITMELSNKEGRDLVRRQIKEINEHCNKLVDKINSTKIKLDRNIDNYNATKEKLDKINEFTNEINDRLNIIKSEVRDFNEKNQSIIWLGNCKDECDSNLKNLKLIKSSSVFPDLNXXXXXXXXXXXXXXXXXXDLTSNLKTELRRINEFENEKLTINKWLESLEKQYETLITSFSISDNLDLKINLIKNFETTSIDQVKISKFEEIQNQLQIQKTIVTNLMYMNQEFEVKDQIKKVNLFHEMIKRSIAIFEETSXXXXXXXXXXXXXXXXXXXAKSILQTKQNSEHNLKELKINVENLFEEFSKLNGEIDIEKFVITSVLSSENVEPXXXXXXXXXXXXXQLKSEMEIISKDIERRLKQIQIEEEIQNKFLENSERFYLFANEINVNIDEFDLQSINNFNQIDTITNKIIEIQKLFENIKETSVKQINQTKDLQIENEVKLARKKLSELNEKYENLFQVVQEKVKQVDAFSKLETDLENWLKYADNYMERYSENKPYSTHLQCETNLENMKEFFHEFEDKEYLLDKLKQMHCANNFPYIEKIEILTESFKKLKTEIENQINHLNKKTSGVLEMAESMESFNQYLRQDYLEYEKLEEIFNKCKNQFNQTAMNKLRLCLNDNAFSIRQETLWNLLQNVRKFSKLVERSRIDIAGNLLDQKETAENELETLKANWSKLSKRINELNNLKMDLDKALEHFNIWLNNSCKWFVNITETRKKVFESNETLQMKNNLQALKDDITEHKVDLSRLQTFVDSLMKICNDETFQKTLDEITKEYNVLFNKCQNECDKCDHLIKLMTKYEISRADVLHWIEASTQTLLKCSDYTLKQSQMKSKLLMIDNLEKELENYGQSKFVEAIQDGEELLGELAGMPMQIVQQQMADLKSDWMEISRQLNQLSSNLRNTTSRSEAFKEMSNRLSNWLDDIEHTGLMDLSHIEHQCEIPFESGNSSSKHDRAKTLLTELNRHKQDFLQLANLATELANPSFDIENSQIQNRYIRLSNNLKDKIEKLNKQQADYDQIKQDIEEMEKWVFQTSIRIINENAEQGKTTNNTIQEIETLIKHSNEIIANILSQEPEIVKIGQAVDSLINISNNKNSDKEKELQDDLSKLIENFNNLKSSSIHKRDHLKDSVKKWDTYQDFLQSTKLFLDNELPNWWRERNQDQMKSAYSNFNNEPILKEILDMDNKLNGLKTTMELEAKACDGILPTIAITASRSQTPNFKSNRSLYSPSSNWSTNKSDVTPNDELIPNILSKSIYEDLDENIKKVSNLKKEIIEKITDWNNFNREKTSFKNWMDNEMLKFSSVLYTEPGISNFASLQKSKLKEIQEEMNYKKQALLNLNTHFKELTSNVSGAADLVLKNLNQDFDETEKKISKLLNREDKGVEADFTDEESNMDIIQERKVPKLNLKNLESPQLFRYESPENLNRFTQTNISKDETDYKFKKTNFSSQTPGTKTTQTNFNDMSNFGTQTNDKYQKKRERKLESELQILNSLKNMNSEFERSKPFPEYNNISSVPMSAKPRSSALESVRRNIYPSYSQTRQTTCSPLMQRIENGYKSRRPLSPSTHSQNLLNKPLSQNSNLNLTKSSGDNLDDLIPTKNKWVDLEINAQLINSSLKSYPFDVPSREFHIDYNTKFEGFPVSLRKKSPQRRSSGXXXXXXXXXXXXXXITDSINRITEDANELRNLSQKLRSVK 13891
NL+ +L+N L ++W + K + K + + DD+ SH+ RKG+HG++ DK + +NK+RL++L +E + +L + A LG EKP+NEV LK L+ K +LE EI+ NEKDL+NH+Q+ ND+ HDW+ + E L ++I P+TK GLIEKQ LL L +LK G+K LKE+KNLQKVVLNETAPDEKENINIQLNAEIEKFNEVFVNLD Q GINETIEKIEDLGE+SDQ+SE+I+EINK+LEKCLNLPSNTLNEKEKLAKELN+T RL+DQQLA+INDLKSQCGSLEHSAALEDLLNKLESLEEHCFEIKTKIEERIKEVDSDIKFQSALEEKLNDLSEIMNEVEIEFDYSKPKESSEAAINESLSQLQKLKAQHEPGKNILKTMIKLRNEFNAPEQCVTACNDLEQKYFDIEDDIKNLQKELEMKTTVWQKFNALKADLDKTCNTAILEIGNEHKKRSGIHGGDCEDKFNLLEDKKKILSNMTNKDPQVDALIEVSGKLGFDKALFDAQNIKRKYLKLIDDLQQEISQNEIDLDNHKKFDQSLFEFEDWMKNTEKIVKQIANLPNDKNGLLEKQNRLEEMKTLKSNGNEMIKNIKHLQNVVINETAGNFKTTLNEKVKNKIENFERVFGDLDQETDNIKETIDKLKVIDEKSNEMERNIREIENTINKCSIVPSESVGDKEKLGKIYRSLEHDIEQHLIDLDSLKQQCNALNATTANSAMINKLNKMTDECKSMKADISQLFSKNVSDLKNLKTFQDKMNEFNESMDRIETEIEKCSPNGCNEAAIKDNIKKLKKFRSLHENSKDVLTDLLRIGFELSGLSQISEASDQAEQKYSDVEDEITKLESKLEMQKNDWSNFNSDKNDLEKWLNEITKKVENLEQISDGIHGGKLSEKEKVLDSHQKLLQEALNREADIKLFLDRSTPLFSAVNQDSPKRVTNTLCKKYEKLLETLTNRIQKNEEDINLHENYAKQIDNFKEENNIIIKRMNEEIASLPNTKEGLKRKVDLLGNLKDLYNQRKMILVNLENLKNAVIDHSSSNYYSNLEQEWDQIIDSFEKSFNPSIENQSKLLLAVQQIEKTESICQDLQHQLENLERRLQEAVDQHISSLNDIDMKLETLKELRYELRDLQTPINDVQRKHCQNPSDVELIQERIEQIAKQHKVLNESISQNINETENHHKQLCNLTTSLNNFKTWLDYSSSQIEEKGKPGNLEMNNLKKNLTSLKQLADSISCQCDDQLSKIREHMLKIHKFSSEKLKDDLQKELNIMNGNVNSLKDKIQTTTEHEINRINEVEKIDILKNEIKENFLKFESQININFKNFDLNEKQNYITQLRNVQNLMKENEKKIEFLETSIQNIIKHSHGKMLDINANKIINKRNSIKIQLNELINKLTQMSDEQMQFTDLLNDTKICIENQHNEINIEISFDNNIDQDKNNLNIVNEYLNINSKLSENKIEILRQKFKTVSRYVNEQENLKLEAEVDKLEKKFHETIELSKDNQSALLLNINNVTEADLFYERTIKWLNSKVSELEQFYVKPETLREKENRLRILNKIKFETEENTSMIKRQMDNLPVLLTVQNKNVDNKINTLKIQLKEIFERVSEEFNIHEEFSENFHSLINNMESCKYQLIQCVESIEFDKENKIIKKNSEEIFTENISNNNKQLNKVNELYQTVKYQTSPGGIAILDTEMQLAQTLSKDIDELFLKLKTKEQKFENLQNKFESLINSIENSLTENEDEMKKLSELKRDLKQKASTKQHLVENILPEIHGTQSLIDELKEVCYEYLSEIIDRNKSRRANDIFYRFSELSRLAESSIKKVQKACEDHELFDKFYKEAVEYFNEINDEIEFVSNLLDVETNTFHELTKLTAKLSSYETQRTEFFQSMHNVESQGQITMELSNKEGRDLVRRQIKEINEHCNKLVDKINSTKIKLDRNIDNYNATKEKLDKINEFTNEINDRLNIIKSEVRDFNEKNQSIIWLGNCKDECDSNLKNLKLIKSSSVFPDLNKGIETIELKLEKLNKKIKDLTSNLKTELRRINEFENEKLTINKWLESLEKQYETLITSFSISDNLDLKINLIKNFETTSIDQVKISKFEEIQNQLQIQKTIVTNLMYMNQEFEVKDQIKKVNLFHEMIKRSIAIFEETSTKINENKTIINKIEKWIINAKSILQTKQNSEHNLKELKINVENLFEEFSKLNGEIDIEKFVITSVLSSENVEPFFNILSNNLSNINQLKSEMEIISKDIERRLKQIQIEEEIQNKFLENSERFYLFANEINVNIDEFDLQSINNFNQIDTITNKIIEIQKLFENIKETSVKQINQTKDLQIENEVKLARKKLSELNEKYENLFQVVQEKVKQVDAFSKLETDLENWLKYADNYMERYSENKPYSTHLQCETNLENMKEFFHEFEDKEYLLDKLKQMHCANNFPYIEKIEILTESFKKLKTEIENQINHLNKKTSGVLEMAESMESFNQYLRQDYLEYEKLEEIFNKCKNQFNQTAMNKLRLCLNDNAFSIRQETLWNLLQNVRKFSKLVERSRIDIAGNLLDQKETAENELETLKANWSKLSKRINELNNLKMDLDKALEHFNIWLNNSCKWFVNITETRKKVFESNETLQMKNNLQALKDDITEHKVDLSRLQTFVDSLMKICNDETFQKTLDEITKEYNVLFNKCQNECDKCDHLIKLMTKYEISRADVLHWIEASTQTLLKCSDYTLKQSQMKSKLLMIDNLEKELENYGQSKFVEAIQDGEELLGELAGMPMQIVQQQMADLKSDWMEISRQLNQLSSNLRNTTSRSEAFKEMSNRLSNWLDDIEHTGLMDLSHIEHQCEIPFESGNSSSKHDRAKTLLTELNRHKQDFLQLANLATELANPSFDIENSQIQNRYIRLSNNLKDKIEKLNKQQADYDQIKQDIEEMEKWVFQTSIRIINENAEQGKTTNNTIQEIETLIKHSNEIIANILSQEPEIVKIGQAVDSLINISNNKNSDKEKELQDDLSKLIENFNNLKSSSIHKRDHLKDSVKKWDTYQDFLQSTKLFLDNELPNWWRERNQDQMKSAYSNFNNEPILKEILDMDNKLNGLKTTMELEAKACDGILPTIAITASRSQTPNFKSNRSLYSPSSNWSTNKSDVTPNDELIPNILSKSIYEDLDENIKKVSNLKKEIIEKITDWNNFNREKTSFKNWMDNEMLKFSSVLYTEPGISNFASLQKSKLKEIQEEMNYKKQALLNLNTHFKELTSNVSGAADLVLKNLNQDFDETEKKISKLLNREDKGVEADFTDEESNMDIIQERKVPKLNLKNLESPQLFRYESPENLNRFTQTNISKDETDYKFKKTNFSSQTPGTKTTQTNFNDMSNFGTQTNDKYQKKRERKLESELQILNSLKNMNSEFERSKPFPEYNNISSVPMSAKPRSSALESVRRNIYPSYSQTRQTTCSPLMQRIENGYKSRRPLSPSTHSQNLLNKPLSQNSNLNLTKSSGDNLDDLIPTKNKWVDLEINAQLINSSLKSYPFDVPSREFHIDYNTKFEGFPVSLRKKSPQRRSSGSPKRNRSKSARNSRITDSINRITEDANELRNLSQKLRSVK
Sbjct: 1839 NLENGIKDLTNALEQKKSNWSRYNLIKSDIEKSLETLKDDINVSHEMRKGIHGKDSKDKETIFHDNKKRLQDLNDKEKVINELIEMAKLLGSEKPVNEVLQLKKTFLEDKDDLENEIKINEKDLKNHRQYENDLDLFHDWILEAESLADKISGTPSTKAGLIEKQNLLNKLKNLKPVGEKMLKEIKNLQKVVLNETAPDEKENINIQLNAEIEKFNEVFVNLDIQDGINETIEKIEDLGEQSDQVSEDISEINKKLEKCLNLPSNTLNEKEKLAKELNSTNRLLDQQLAKINDLKSQCGSLEHSAALEDLLNKLESLEEHCFEIKTKIEERIKEVDSDIKFQSALEEKLNDLSEIMNEVEIEFDYSKPKESSEAAINESLSQLQKLKAQHEPGKNILKTMIKLRNEFNAPEQCVTACNDLEQKYFDIEDDIKNLQKELEMKTTVWQKFNALKADLDKTCNTAILEIGNEHKKRSGIHGGDCEDKFNLLEDKKKILSNMTNKDPQVDALIEVSGKLGFDKALFDAQNIKRKYLKLIDDLQQEISQNEIDLDNHKKFDQSLFEFEDWMKNTEKIVKQIANLPNDKNGLLEKQNRLEEMKTLKSNGNEMIKNIKHLQNVVINETAGNFKTTLNEKVKNKIENFERVFGDLDQETDNIKETIDKLKVIDEKSNEMERNIREIENTINKCSIVPSESVGDKEKLGKIYRSLEHDIEQHLIDLDSLKQQCNALNATTANSAMINKLNKMTDECKSMKADISQLFSKNVSDLKNLKTFQDKMNEFNESMDRIETEIEKCSPNGCNEAAIKDNIKKLKKFRSLHENSKDVLTDLLRIGFELSGLSQISEASDQAEQKYSDVEDEITKLESKLEMQKNDWSNFNSDKNDLEKWLNEITKKVENLEQISDGIHGGKLSEKEKVLDSHQKLLQEALNREADIKLFLDRSTPLFSAVNQDSPKRVTNTLCKKYEKLLETLTNRIQKNEEDINLHENYAKQIDNFKEENNIIIKRMNEEIASLPNTKEGLKRKVDLLGNLKDLYNQRKMILVNLENLKNAVIDHSSSNYYSNLEQEWDQIIDSFEKSFNPSIENQSKLLLAVQQIEKTESICQDLQHQLENLERRLQEAVDQHISSLNDIDMKLETLKELRYELRDLQTPINDVQRKHCQNPSDVELIQERIEQIAKQHKVLNESISQNINETENHHKQLCNLTTSLNNFKTWLDYSSSQIEEKGKPGNLEMNNLKKNLTSLKQLADSISCQCDDQLSKIREHMLKIHKFSSEKLKDDLQKELNIMNGNVNSLKDKIQTTTEHEINRINEVEKIDILKNEIKENFLKFESQININFKNFDLNEKQNYITQLRNVQNLMKENEKKIEFLETSIQNIIKHSHGKMLDINANKIINKRNSIKIQLNELINKLTQMSDEQMQFTDLLNDTKICIENQHNEINIEISFDNNIDQDKNNLNIVNEYLNINSKLSENKIEILRQKFKTVSRYVNEQENLKLEAEVDKLEKKFHETIELSKDNQSALLLNINNVTEADLFYERTIKWLNSKVSELEQFYVKPETLREKENRLRILNKIKFETEENTSMIKRQMDNLPVLLTVQNKNVDNKINTLKIQLKEIFERVSEEFNIHEEFSENFHSLINNMESCKYQLIQCVESIEFDKENKIIKKNSEEIFTENISNNNKQLNKVNELYQTVKYQTSPGGIAILDTEMQLAQTLSKDIDELFLKLKTKEQKFENLQNKFESLINSIENSLTENEDEMKKLSELKRDLKQKASTKQHLVENILPEIHGTQSLIDELKEVCYEYLSEIIDRNKSRRANDIFYRFSELSRLAESSIKKVQKACEDHELFDKFYKEAVEYFNEINDEIEFVSNLLDVETNTFHELTKLTAKLSSYETQRTEFFQSMHNVESQGQITMELSNKEGRDLVRRQIKEINEHCNKLVDKINSTKIKLDRNIDNYNATKEKLDKINEFTNEINDRLNIIKSEVRDFNEKNQSIIWLGNCKDECDSNLKNLKLIKSSSVFPDLNKGIETIELKLEKLNKKIKDLTSNLKTELRRINEFENEKLTINKWLESLEKQYETLITSFSISDNLDLKINLIKNFETTSIDQVKISKFEEIQNQLQIQKTIVTNLMYMNQEFEVKDQIKKVNLFHEMIKRSIAIFEETSTKINENKTIINKIEKWIINAKSILQTKQNSEHNLKELKINVENLFEEFSKLNGEIDIEKFVITSVLSSENVEPFFNILSNNLSNINQLKSEMEIISKDIERRLKQIQIEEEIQNKFLENSERFYLFANEINVNIDEFDLQSINNFNQIDTITNKIIEIQKLFENIKETSVKQINQTKDLQIENEVKLARKKLSELNEKYENLFQVVQEKVKQVDAFSKLETDLENWLKYADNYMERYSENKPYSTHLQCETNLENMKEFFHEFEDKEYLLDKLKQMHCANNFPYIEKIEILTESFKKLKTEIENQINHLNKKTSGVLEMAESMESFNQYLRQDYLEYEKLEEIFNKCKNQFNQTAMNKLRLCLNDNAFSIRQETLWNLLQNVRKFSKLVERSRIDIAGNLLDQKETAENELETLKANWSKLSKRINELNNLKMDLDKALEHFNIWLNNSCKWFVNITETRKKVFESNETLQMKNNLQALKDDITEHKVDLSRLQTFVDSLMKICNDETFQKTLDEITKEYNVLFNKCQNECDKCDHLIKLMTKYEISRADVLHWIEASTQTLLKCSDYTLKQSQMKSKLLMIDNLEKELENYGQSKFVEAIQDGEELLGELAGMPMQIVQQQMADLKSDWMEISRQLNQLSSNLRNTTSRSEAFKEMSNRLSNWLDDIEHTGLMDLSHIEHQCEIPFESGNSSSKHDRAKTLLTELNRHKQDFLQLANLATELANPSFDIENSQIQNRYIRLSNNLKDKIEKLNKQQADYDQIKQDIEEMEKWVFQTSIRIINENAEQGKTTNNTIQEIETLIKHSNEIIANILSQEPEIVKIGQAVDSLINISNNKNSDKEKELQDDLSKLIENFNNLKSSSIHKRDHLKDSVKKWDTYQDFLQSTKLFLDNELPNWWRERNQDQMKSAYSNFNNEPILKEILDMDNKLNGLKTTMELEAKACDGILPTIAITASRSQTPNFKSNRSLYSPSSNWSTNKSDVTPNDELIPNILSKSIYEDLDENIKKVSNLKKEIIEKITDWNNFNREKTSFKNWMDNEMLKFSSVLYTEPGISNFASLQKSKLKEIQEEMNYKKQALLNLNTHFKELTSNVSGAADLVLKNLNQDFDETEKKISKLLNREDKGVEADFTDEESNMDIIQERKVPKLNLKNLESPQLFRYESPENLNRFTQTNISKDETDYKFKKTNFSSQTPGTKTTQTNFNDMSNFGTQTNDKYQKKRERKLESELQILNSLKNMNSEFERSKPFPEYNNISSVPMSAKPRSSALESVRRNIYPSYSQTRQTTCSPLMQRIENGYKSRRPLSPSTHSQNLLNKPLSQNSNLNLTKSSGDNLDDLIPTKNKWVDLEINAQLINSSLKSYPFDVPSREFHIDYNTKFEGFPVSLRKKSPQRRSSGSPKRNRSKSARNSRITDSINRITEDANELRNLSQKLRSVK 5432 HSP 2 Score: 2593.53 bits (6721), Expect = 0.000e+0 Identity = 1537/2051 (74.94%), Postives = 1734/2051 (84.54%), Query Frame = 2
Query: 188 KDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXXXXXALGMANDPNAKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNELDIVKDFNDKVDKNFENLNSKNNYDIFADLMSQRDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLMEPFPNVHDKTFNDKVLQKLKEHESIFNKKNDVLAKFREVLQNPPANISPKQLEAMKTRMENVCKAEGPVREKLNIFGIQANLKNKAQKWAVDLNSWDSPIQSKQDLLDKIEQFNISMENGTSMDKFTSQLDELVKRKVKFCKENPVLDEDLLNFINKAINECEEENDILPEKFESTLMKLENLSSEWDEISDGEQKIETFSRRLSKALQLDDFQQQRSLVDQLPEVLDLLNDVKYKIQNDLTPHCSEKLLYTMXXXXXXXXXXXXXXGAXXXXXXXXXXXXXXXXXXAARDTLIDEIFSCGQANVDSIKQWMNDLDQCMETPINGSSADLQYVLSKLKDLDKESPKIQKLIDQGYQKVDDLENENSPEKAQELKESLNEFQKKFKRYTEKEIPKNLQNLKTFIDTLNIVENDINDLEKTMKEGEFIKNHLDDLEFSNGTDDIIFKEQEFLEKENEXXXXXXXXXXXXXXXXXXVESTDLKIDLKPLEKRIFDSENVLQDLLTNAKENLTANNQCNEACTSADQSLECLLDQIEKNSSINNDEEGQKTKLKNIQNFXXXXXXXXKQINAAVAXXXXXXXXXXXXXXDKIDNSISKIKQKTVSIKENLQKTKVNLSNNLNDWQDFKQTKDLMTKCFDDIIDDLKESHQKRKGVHGENLTDKADXXXXXXXXXXXXIKQEDXXXXXXXXXXXXXXEKPINEVKNLKDQILKQKANLEEEIQQNEKDLENHQQFNNDIQSLHDWLAQTELLTNQIQNLPNTKEGLIEKQKLLEDLNSLKSTGDKKLKELKNLQKVVLNETAPDEKENINIQLNAEIEKFNEVFVNLDKQGGINETIEKIEDLGEKSDQISENINEINKRLEKCLNLPSNTLNEKEKLAKELNNTIRLVDQQLAQINDLKSQCGSLEHSAALEDLLNKLESLEEHCFXXXXXXXXXXXXVDSDIKFQSALEEKLNDLSEIMNEVEIEFDYSKPKESSEAAINESLSQLQKLKAQHEPGKNILKTMIKLRNEFNAPEQCVTACNDLEQKYFDIEDDIKNLQKELEMKTTVWQKFNALKADLDKTCNTAILEIGNEHKKRSGIHGGDCEDKFNLLEDKKKILSNMTNKDPQVDALIEVSGKLGFDKALFDAQNIKRKYLKLIDDLQQEISQNEIDLDNHKKFDQSLFEFEDWMKNTEKIVKQIANLPNDKNGLLEKQNRLEEMKTLKSNGNEMIKNIKHLQNVVINETAGNFKTTLNEKVKNKIENFERVFGDLDQETDNIKETIDKLKVIDEKSXXXXXXXXXXXXXXXKCSIVPSESVGDKEKLGKIYRSLEHDIEQHLIDLDSLKQQCNALNATTANSAMINKLNKMTDECKSMKADISQLFSKNVSDLKNLKTFQDKMNEFNESMDRIETEIEKCSPNGCNEAAIKDNIKKLKKFRSLHENSKDVLTDLLRIGFELSGLSQISEASDQAEQKYSDVEDEITKLESKLEMQKNDWSNFNSDKNDLEKWLNEITKKVENLEQISDGIHGGKLSEKEKVLDSHQKLLQEALNREADIKLFLDRSTPLFSAVNQDSPKRVTNTLCKKYEKLLETLTNRIQKNEEDINLHENYAKQIDNFKEENNIII--KRMNEEIASLPNTKEGLKRKVDLLGNLKDLYNQRKMILVNLENLKNAVIDHSSSNYYSNLEQEWDQIIDSFEKSF 6334
K+EQEKMQKKTFTKWMNSYLCQKKPPIIIKDLMKDLSDGLLLLDLLEILTKTTLKKEKPKNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAILHFQIEEQEEFLLQALGMANDPNAKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNELDIVKDFNDKVDKNFENLNSKNNYDIFADLMSQRDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLMEPFPNVHDKTFNDKVLQKLKEHESIFNKKNDVLAKFREVLQNPPANISPKQLEAMKTRMENVCKAEGPVREKLNIFGIQANLKNKAQKWAVDLNSWDSPIQSKQDLLDKIEQFNISMENGTSMDKFTSQLDELVKRKVKFCKENPVLDEDLLNFINKAINECEEENDILPEKFESTLMKLENLSSEWDEISDGEQKIETFSRRLSKALQLDDFQQQRSLVDQLPEVLDLLNDVKYKIQNDLTPHCSEKLLYTMKENLNELEINLKELGAQVVDKVEKQKQKIEQQQQAARDTLIDEIFSCGQANVDSIKQWMNDLDQCMETPINGSSADLQYVLSKLKDLDKESPKIQKLIDQGYQKVDDLENENSPEKAQELKESLNEFQKKFKRYTEKEIPKNLQNLKTFIDTLNIVENDINDLEKTMKEGEFIKNHLDDLEFSNGTDDIIFKEQEFLEKENEISKSLIKDKDLLKHIKKLVESTDLKIDLKPLEKRIFDSENVLQDLLTNAKENLTANNQCNEACTSADQSLECLLDQIEKNSSINNDEEGQKTKLKNIQNFEEEIEEVEKQINAAVALRNNLLSNLNKSNLDKIDNSISKIKQKTVSIKENLQKTKVNLSNNLNDWQDFKQTKDLMTKCFDDIIDDLKESHQKRKGVHGENLTDKADLLEENKERLENLIKQEDKLKDLNKKALKLGLEKPINEVKNLKDQILKQKANLEEEIQQNEKDLENHQQFNNDIQSLHDWLAQTELLTNQIQNLPNTKEGLIEKQKLLEDLNSLKSTGDKKLKELKNLQKVVLNETAPDEKENINIQLNAEIEKFNEVFVNLDKQGGINETIEKIEDLGEKSDQISENINEINKRLEKCLNLPSNTLNEKEKLAKELNNTIRLVDQQLAQINDLKSQC LE+ A+E+LLN LESLEE C K KIEE++ E +SDIK Q ALE L L+++MNE E E S K++ +A+ E+L +L+ LK++ E KNIL+ + + +++FN P+ C+ AC ++KY D++D+I L++ L + W +F++ K+ ++++ T +I N H +GIHGGDC+DK +LL +KK L ++ ++ + + L + KLG + + + QN+K + LK ++L++EI QNE DL+NH++F+ + DW+ TE + QI NLPN K GL+EKQ LE++ +LKS G++ +K +K+LQ VV+NETA + K +N ++ +IE F VF +LD++ I ETI+K++ + EKS+++ NI EI + KC +PS ++ +KEKL K + ++Q L ++ LK QC +L A +++KL + ++C K++I +N ++K F++K++EF M+ E EI P +E AI+++++KL+ +S H K+ L ++L+ EL + SE ++ E+KY ++E+ I L + LE +K++WS +N K+D+EK L + + ++ GIHG +KE + ++K LQ+ ++E I ++ + L S + P L K + + + L N I+ NE+D+ H Y +D F ++ I+ + + ++I+ P+TK GL K +LL LK+L + +L ++NL+ V++ ++ + N+ + + I+ F + F
Sbjct: 16 KNEQEKMQKKTFTKWMNSYLCQKKPPIIIKDLMKDLSDGLLLLDLLEILTKTTLKKEKPKNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAILHFQIEEQEEFLLQALGMANDPNAKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPPNELDIVKDFNDKVDKNFENLNSKNNYDIFADLMSQRDDMKLLLDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESLMEPFPNVHDKTFNDKVLQKLKEHESIFNKKNDVLAKFREVLQNPPANISPKQLEAMKTRMENVCKAEGPVREKLNIFGIQANLKNKAQKWAVDLNSWDSPIQSKQDLLDKIEQFNISMENGTSMDKFTSQLDELVKRKVKFCKENPVLDEDLLNFINKAINECEEENDILPEKFESTLMKLENLSSEWDEISDGEQKIETFSRRLSKALQLDDFQQQRSLVDQLPEVLDLLNDVKYKIQNDLTPHCSEKLLYTMKENLNELEINLKELGAQVVDKVEKQKQKIEQQQQAARDTLIDEIFSCGQANVDSIKQWMNDLDQCMETPINGSSADLQYVLSKLKDLDKESPKIQKLIDQGYQKVDDLENENSPEKAQELKESLNEFQKKFKRYTEKEIPKNLQNLKTFIDTLNIVENDINDLEKTMKEGEFIKNHLDDLEFSNGTDDIIFKEQEFLEKENEISKSLIKDKDLLKHIKKLVESTDLKIDLKPLEKRIFDSENVLQDLLTNAKENLTANNQCNEACTSADQSLECLLDQIEKNSSINNDEEGQKTKLKNIQNFEEEIEEVEKQINAAVALRNNLLSNLNKSNLDKIDNSISKIKQKTVSIKENLQKTKVNLSNNLNDWQDFKQTKDLMTKCFDDIIDDLKESHQKRKGVHGENLTDKADLLEENKERLENLIKQEDKLKDLNKKALKLGLEKPINEVKNLKDQILKQKANLEEEIQQNEKDLENHQQFNNDIQSLHDWLAQTELLTNQIQNLPNTKEGLIEKQKLLEDLNSLKSTGDKKLKELKNLQKVVLNETAPDEKENINIQLNAEIEKFNEVFVNLDKQGGINETIEKIEDLGEKSDQISENINEINKRLEKCLNLPSNTLNEKEKLAKELNNTIRLVDQQLAQINDLKSQCKHLENCEAVEELLNNLESLEEQCNIRKAKIEEKMNETESDIKKQVALENNLKILADLMNETETEMKISVTKQTGASAVEENLEKLKGLKSKLESEKNILENIEEQKDDFNVPKHCLMACKSSKKKYLDLKDEIHQLEENLNLMKNNWSEFDSAKSKIEESLETIGNDIENMHVTHNGIHGGDCDDKVSLLNEKKNELDDLIRQEEETNDLFSKAKKLGSNAPMIEIQNLKERILKQKENLKKEIKQNEKDLENHQQFNNDIQSLHDWLAQTELLTNQIQNLPNTKEGLIEKQKLLEDLNSLKSTGDKKLKELKNLQKVVLNETAPDEKENINIQLNAEIEKFNEVFVNLDKQG-GINETIEKIEDLGEKSDQISENINEINKRLEKCLNLPSNTLNEKEKLAKELNNTIRLVDQQLAQINDLKSQCESLENCEAVEELLDKLESLEEQCNENKSEIEDKIVENNINIKMQAAFEEKLDEFANLMNEAEIEITSL-PKENSEIAIEESLQKLENIKSKHLPGKNTLEEILKSQTELRIPQEYSETCEKYEEKYCNLENGIKDLTNALEQKKSNWSRYNLIKSDIEKSLETLKDDINVSHEMRKGIHGKDSKDKETIFHDNKKRLQDLNDKEKVINELIEMAKLLGS----EKPVNEVLQLKKTFLEDKDDLENEIKINEKDLKNHRQYENDLDLF---HDWILEAESLADKISGTPSTKAGLIEKQNLLNKLKNLKPVGEKMLKEIKNLQKVVLNETAPDEKENINIQLNAEIEKFNEVF 2057
BLAST of Nesprin-1 vs. Planmine SMEST
Match: SMESG000069851.1 (SMESG000069851.1) HSP 1 Score: 238.424 bits (607), Expect = 4.989e-62 Identity = 161/279 (57.71%), Postives = 199/279 (71.33%), Query Frame = 2
Query: 146 MDRKDTVVKKGVLL----KDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAXXXXXXXXXXXXXXXALGMANDPNAKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINS 970
M+ D+V K L KDEQE++Q+KTFT W+N+YL Q PP I +L + + DGL L+ LLE +T L+KE+PKNMQKIH LSNI TALEF+++ +KIKLVNIN +D+ DG+P+I+LGL+WT IL FQIEEQEE L+ ALG D K AK L+ W N + DKY LN+ DFG SW DG+AFNALVHNIDP+LV+ ++ TNKE L+ AF AE +LGIP LLD +DVDV KPDEKSIMTY+ QFLKSYPEG K I E I A N+
Sbjct: 1 MEDHDSVKGKTETLILSKKDEQERVQRKTFTNWINTYLVQAHPPYKIDNLYESIKDGLCLIHLLEAMTGEKLRKEQPKNMQKIHRLSNINTALEFLKS-RKIKLVNINATDIADGRPSIILGLMWTVILFFQIEEQEEILIGALGADYDG----KLNAKTSLLNWVNKTIGDKYNLNVTDFGPSWRDGKAFNALVHNIDPSLVDWNGVKNKTNKENLQEAFKQAE-QLGIPHLLDVQDVDVAKPDEKSIMTYITQFLKSYPEGGKE--IEENIVATNNA 271 HSP 2 Score: 90.1225 bits (222), Expect = 4.797e-17 Identity = 240/1149 (20.89%), Postives = 479/1149 (41.69%), Query Frame = 2
Query: 10145 ARKKLSELNEKYENLFQVVQEKVKQVDAFSKLETDLENWLKYADNYMERYSENKPYSTHLQCETNLENMKEFFHEFEDKEYLLDKLKQMHCANNFPYIEKIEILT------ESFKKLKTEIENQINHLNKKTSGVLEMAESMESFNQYLRQDYLEYEKL-----------EEIFNKCKNQFNQTAMNKLRL-CLNDNAFSIRQETLWNL--LQNVRKFSKLVERSRIDIAGNLLDQKETAENELETLKANWSKLSKRINELNNLKMDLDKALEHFNIWLNNSCKWFVNITETRKKVFESNETLQMKNNLQALKDDITEHKVDLSRL----QTFVDSLMKICNDETFQKTLDEITKEYNVLFNKCQNECDKCDHLIKLMTKYEISRADVLHWIEASTQTLLKCSDYTLKQSQMKSKLLMIDNLEKELEN------YGQSKFVEAIQDGEELLGELAGMPMQIV------QQQMADLKSDWMEISRQLNQLSSNLRNTTSRSEAFKEMSNRLSNWLDDIEHTGLMDLSHIEHQCEIPFESGNSSSKHDRAKTLLTELNRHKQDFLQLANLATELAN----PSFDIENSQIQNRYIRLSNNLKDKIEKLNKQQADYDQIKQDIEEMEKWVFQTSIRIINENAEQGKTTNNTIQEIETLIKHSNEIIANILSQEPEIVKIGQAVDSLI-------NISNNKNSDKEKELQDDLSKLIENFNNLKSSSIHKRDHLKDSVKKWDTYQDFLQSTKLFLDNELPNWWRERNQDQMKSAYSNFNN-EPILKEILDMDNKLNGLKTTMELEAKACDGILPTIAITASRSQTPNFKSNRSLYSPSSNWSTNKSDVTPNDELIPNILSKSIYEDLDENIKKVSNLKKEIIEKITDWNNFNREKTSFKNWMDNEMLKFSSVLYTEPGISN--FASLQKSKLKEIQEEMNYKKQALLNLNTHFKELTSNVSGAADLVLKNLNQDFDETEKKISKLLNREDKGVEA---DFTDEESNMDIIQERKVPKLNLKNLESPQLFRYESPENLNRFTQTNISKDETDYKFKKTNF-----SSQTPGTKTTQTN--FNDMSNFGTQTNDKYQKKRERKLESELQILNSLKNMNSEFERSKPFPEYNNISSVPMSA--KPRSSALESVRRN 13405
A +KL++ ++ NL +++ +K + K D +N + A ++E K +T + ++E MK ++ +++KL + +N + K + + E+ K K EI N + LNK G L++ + + + Q L + + EE NK N + ++K++L C + A S E L N L N +F E + + NL E A+ ++ N + IN N+ + WLN + K + ET + ++ + + L+ L +D+ E + + ++ + DS + LD+I ++ L +++ + I+ +++ S W+ +TQ LLK SD +KQ ID+ + EN YG+ I G++ L L Q Q+++ DL+ +W + +Q++ ++ N+ + F + N+L ++ + E+ G+ +L +E K ++ EL+ D +L A E+ PS + I +RY + NL+ ++ K + + D++ K + EKW+ T RII EN + + +E K ++I + + ++VKIG+ + S + + S N +S E E+ D+ L + NL ++ + L + + W Y+D +Q +L N+L +WWR + NF + + ++E ++ LN + M++ CD + +S + NF + + N S TP L++S+ L++NI+++ E+ + +W +F+++ F+ W++ + F S + +P + + Q++ +++++E++ +++ H +L + L + ++ ++++ KLL R+D+ ++A D+ D+++ + + +LNL + Q PE N T T +T + K +F ++ G + + N + M T+D +KL + + LKN F + P + P K RS+A ESVRRN
Sbjct: 849 ALRKLNQTKQQLSNLQTNIKDAIKDAENNVKNHQDFDNKMNGASEWLEMAKALKLDATSKETPGSIEEMKR-------RKDIIEKL--IESKSNGENLVKAAVTSGEIVAKETSLKGKEEILNGVRGLNK---GFLDLLDGLGAAKQSLEMKLAKASNINRDLDALVNWAEEFENKLFN-ITDSDLDKIKLLCDDAQAKSYLAENLVNQTKLMNDPEFQSRAENIKELVKHNL----ENAQQMYSQIRENLQAYNGLINNCKNM-----------DSWLNEAEKKMARLGETSG--YSPDDLAKNLSLLEKLAEDVKEKRNYIEKINNQGRDLTDS--SPSKGKETNALLDKINNKHKKLMENLEDKNQEVRRNIEDQKEFDESIHKAQQWMNDATQKLLKYSD--IKQCSP----TQIDSFSRNFENIVDSVPYGEEIVSSTIYTGQKHLEHLRQSKRQDSNNYERDQKRINDLEKNWGDFQKQIDLVNKNVHRVKDSLDEFNLLKNKLEEFITEKEN-GMKELPSVEI-----------------LKYIINELDDSINDLDKLQTKAVEVGGSLNYPSAIMVAKGITDRYQNMKKNLESELNKSKQLENDWNAYKNALNVCEKWIVDTGFRII-ENDYSAYSPEDAQVRLEEYSKLCDQI-QSFGEEVNKVVKIGKQLASKLPKDQKPDSNSMNFSSHSEPEIHADIENLQRSHKNLVENANQTKSRLIEQLDNWRKYRDLVQVNDKYLTNDLTDWWRNKKY----FPPQNFKDVDENIREAEEILRVLNDKQNEMKMTKSNCDSL-------SSENGPRNFSATAEI-----NRKRKISSTTPLSR-----LAESVETGLEKNIEEIKKYIPELENLLKEWQSFDKDTAEFEIWINEKEQMFESTI-GKPSMKSTCLTDKQRTFGEQLKKEIDGQEK-------HINDLLEKARVVGSRKINPLLKRIEDLKRQLKKLLERKDEEIDAVDFDYVDKQT---VGCQNNEMQLNLSETIATQTL----PEKYNISTSTEPRTRKTKVQTFKQDFIVPVNANNVFGLRNSGGNRGLSKMLYPYCCTSDLLN----QKLHLDYVHGSRLKNNQKSFIPNAPTRPIDGGKYPPRLGISKVRSAAEESVRRN 1899
BLAST of Nesprin-1 vs. Planmine SMEST
Match: SMESG000016745.1 (SMESG000016745.1) HSP 1 Score: 213.386 bits (542), Expect = 3.892e-54 Identity = 183/552 (33.15%), Postives = 298/552 (53.99%), Query Frame = 2
Query: 188 KDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTA----XXXXXXXXXXXXXXXALGMANDPNAKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPP--NELDIVKDFNDKVDK--------NFENLNSKNNY-DIFADLMSQRDDMKLL--LDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESL-------MEPFPNVHDKTFNDKVLQKLKEHESIFNKK---NDVLAKFREVLQNPPAN--ISPKQLEAMKTRMENVCKAEGPVREKLNIFGIQANLKNKAQKWAVDLNSWDSPIQSKQDLLDKIEQFNISMENGTSMDKFTSQLDELVKRKVKFCKENPVLDE 1756
KDEQ+ +QKKTFTKW+N YL + +I+KDL D+ DGL+L+ LLE+L+ +T++KE+ NM+K+H LSN++ AL ++ +++KIKLVNINPSD+V+GKP IVLGL+W + +++ A+ AN N+ K L+ W N + +Y + I DFG+SW G AF+AL+ +P LV+M+ + +G ++ L++AF+IAE LGI KLLDSEDV EKPDEKSIMTYV+QFL+ +PE+ +++ +SM +P NE + NDK+ + E L N+ D+F + + +++++L+ D+ S+ L LD DF + + QW LD+ + + + WL +E L ++ + + +D +Q +KE+E+ F + LA+ + + N N + +++ R++ V K E +R+KL + A+LK K ++ L W S + D++ F +M NG F + + E++ K +P E
Sbjct: 11 KDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYL-SERKIKLVNINPSDIVEGKPVIVLGLIWLIILFFQIQEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTI--TRPESPRKKLK-------LSMPEPAKSNE----RGVNDKIKRFIINVKESRIEKLKQIENFNDVFKLISNLKNELELIPEWDQTSSTGDLLLDQ--------DFKAAKRLVLSCQWLLDESVNNGWKN-LCKWLISSERILEFHKNNQIDVSKEISPELLDDLTVQ-IKEYETHFKNSPFHSPTLAELKRCMINTDKNNKVFISYTISVERRIQKVVKEEFSIRQKLLLLHKIASLKMKEKEINYKLQYWKREFDSLANAEDRLLDFESAMANGN----FVAIVTEMINDIEKLLSADPTFKE 534
BLAST of Nesprin-1 vs. Planmine SMEST
Match: SMESG000016745.1 (SMESG000016745.1) HSP 1 Score: 213.001 bits (541), Expect = 4.776e-54 Identity = 181/552 (32.79%), Postives = 298/552 (53.99%), Query Frame = 2
Query: 188 KDEQEKMQKKTFTKWMNSYLCQKKPPIIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTA----XXXXXXXXXXXXXXXALGMANDPNAKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPP--NELDIVKDFNDKVDK--------NFENLNSKNNY-DIFADLMSQRDDMKLL--LDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESL-------MEPFPNVHDKTFNDKVLQKLKEHESIFNKK---NDVLAKFREVLQNPPAN--ISPKQLEAMKTRMENVCKAEGPVREKLNIFGIQANLKNKAQKWAVDLNSWDSPIQSKQDLLDKIEQFNISMENGTSMDKFTSQLDELVKRKVKFCKENPVLDE 1756
++EQ+ +QKKTFTKW+N YL + +I+KDL D+ DGL+L+ LLE+L+ +T++KE+ NM+K+H LSN++ AL ++ +++KIKLVNINPSD+V+GKP IVLGL+W + +++ A+ AN N+ K L+ W N + +Y + I DFG+SW G AF+AL+ +P LV+M+ + +G ++ L++AF+IAE LGI KLLDSEDV EKPDEKSIMTYV+QFL+ +PE+ +++ +SM +P NE + NDK+ + E L N+ D+F + + +++++L+ D+ S+ L LD DF + + QW LD+ + + + WL +E L ++ + + +D +Q +KE+E+ F + LA+ + + N N + +++ R++ V K E +R+KL + A+LK K ++ L W S + D++ F +M NG F + + E++ K +P E
Sbjct: 52 RNEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYL-SERKIKLVNINPSDIVEGKPVIVLGLIWLIILFFQIQEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTI--TRPESPRKKLK-------LSMPEPAKSNE----RGVNDKIKRFIINVKESRIEKLKQIENFNDVFKLISNLKNELELIPEWDQTSSTGDLLLDQ--------DFKAAKRLVLSCQWLLDESVNNGWKN-LCKWLISSERILEFHKNNQIDVSKEISPELLDDLTVQ-IKEYETHFKNSPFHSPTLAELKRCMINTDKNNKVFISYTISVERRIQKVVKEEFSIRQKLLLLHKIASLKMKEKEINYKLQYWKREFDSLANAEDRLLDFESAMANGN----FVAIVTEMINDIEKLLSADPTFKE 575 The following BLAST results are available for this feature:
BLAST of Nesprin-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Nesprin-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Nesprin-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Nesprin-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Nesprin-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Nesprin-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Nesprin-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Nesprin-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Nesprin-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Nesprin-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Nesprin-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Nesprin-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Nesprin-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Nesprin-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30021613 ID=SMED30021613|Name=Nesprin-1|organism=Schmidtea mediterranea sexual|type=transcript|length=14045bpback to top protein sequence of SMED30021613-orf-1 >SMED30021613-orf-1 ID=SMED30021613-orf-1|Name=SMED30021613-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=4583bp MDRKDTVVKKGVLLKDEQEKMQKKTFTKWMNSYLCQKKPPIIIKDLMKDLback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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