MICOS complex subunit MIC60

Overview
NameMICOS complex subunit MIC60
Smed IDSMED30021516
Length (bp)2444
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of MICOS complex subunit MIC60 (SMED30021516) t-SNE clustered cells

Violin plots show distribution of expression levels for MICOS complex subunit MIC60 (SMED30021516) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of MICOS complex subunit MIC60 (SMED30021516) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for MICOS complex subunit MIC60 (SMED30021516) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30021516

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30021516SMESG000066687.1 dd_Smed_v4_1605_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30021516SMESG000066687.1 dd_Smed_v4_1605_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30021516SMESG000066687.1 dd_Smed_v4_1605_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of MICOS complex subunit MIC60 vs. Ensembl Human
Match: IMMT (inner membrane mitochondrial protein [Source:HGNC Symbol;Acc:HGNC:6047])

HSP 1 Score: 207.994 bits (528), Expect = 4.964e-57
Identity = 137/413 (33.17%), Postives = 230/413 (55.69%), Query Frame = 2 
Query:  965 IEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNV-SNW----TKKHTDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREAL----LKEREKMRASIDGWRM-------RVEGIEAAVEGRADEEILSREAQDMWVACHAL-HGVLTGNGATP--PLARYLNSFEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECDTEIDPESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSSKTAGS 2146
            ++ AQ  A++ +QY EL+ Q ++ FK+EL S+ P V   W         DKLS DDLN++I HAHRR+ QL   +AE ++ E   +  AL +Q+ +++ + +  V   LE  RS+   E   ++++++   E E+R  L RQA+AH +H+  +L++Q+ E+  +    + E L    L+ R   +  +D + +       R+ GIE AV+  A  E  +R+A  +W++  AL + + T +  TP  PL   + + +  A  S     Q    +IP  +L +GV ++  L  RF  ++++ RRVAMIDET  SL  Y +S+L+SL+L  P  L +   E+ PE  +I+T ++++ A   I   D +LA + +N LKG  R +  DW+ +AR+ LETK   + L++Y S+   G+
Sbjct:  200 VQAAQSEAKVVSQYHELVVQARDDFKRELDSITPEVLPGWKGMSVSDLADKLSTDDLNSLIAHAHRRIDQLNRELAEQKATEKQHITLALEKQKLEEKRAFDSAVAKALEHHRSEIQAEQDRKIEEVRDAMENEMRTQLRRQAAAHTDHLRDVLRVQEQELKSEFEQNLSEKLSEQELQFRRLSQEQVDNFTLDINTAYARLRGIEQAVQSHAVAEEEARKAHQLWLSVEALKYSMKTSSAETPTIPLGSAVEAIK--ANCSDNEFTQALTAAIPPESLTRGVYSEETLRARFYAVQKLARRVAMIDETRNSLYQYFLSYLQSLLLFPPQQL-KPPPELCPE--DINTFKLLSYASYCIEHGDLELAAKFVNQLKGESRRVAQDWLKEARMTLETKQIVEILTAYASAVGIGT 607
[Close]
BLAST of MICOS complex subunit MIC60 vs. Ensembl Human
Match: IMMT (inner membrane mitochondrial protein [Source:HGNC Symbol;Acc:HGNC:6047])

HSP 1 Score: 209.149 bits (531), Expect = 8.344e-57
Identity = 181/673 (26.89%), Postives = 327/673 (48.59%), Query Frame = 2 
Query:  209 IFLGISSITLLGTGLSYYYNDDFREKVAPYLPKRTKQFLDEYFDIPITDRIMKKWDSFNF-FDKLSIKSN--KMESFTSRFKGSKESNGPESSQKESKPFMNESVKK--VPRTPSEKIKDDVEKEAERLKKLNEVFSNKLSNQIDSVEAASTSVILHLMEYADKIQDHSQKLKRAIEDD---GTTIPNPWEEVNESNHLQQTAKTKSDKEMKRLELAIKQLELSINEGNHSEDLKSNPSIHTGQEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNV-SNW----TKKHTDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREAL----LKEREKMRASIDGWRM-------RVEGIEAAVEGRADEEILSREAQDMWVACHAL-HGVLTGNGATP--PLARYLNSFEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECDTEIDPESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSSKTAGS 2146
            +F+G     + GT L   ++  FRE V   +P     + D+ F++ +         ++N    K SI+S   K+ S +   K SK+       QK   P          +   P E++   + ++ ++ +   E  +  L + +    + +   I         +  HS  LK A+++    G      W  V  +   ++ A  ++   + + +  +++++  I      E   + P I   +  L +    +   +  ++ AQ  A++ +QY EL+ Q ++ FK+EL S+ P V   W         DKLS DDLN++I HAHRR+ QL   +AE ++ E   +  AL +Q+ +++ + +  V   LE  RS+   E   ++++++   E E+R  L RQA+AH +H+  +L++Q+ E+  +    + E L    L+ R   +  +D + +       R+ GIE AV+  A  E  +R+A  +W++  AL + + T +  TP  PL   + + +  A  S     Q    +IP  +L +GV ++  L  RF  ++++ RRVAMIDET  SL  Y +S+L+SL+L  P  L +   E+ PE  +I+T ++++ A   I   D +LA + +N LKG  R +  DW+ +AR+ LETK   + L++Y S+   G+
Sbjct:   52 LFVGGG---IGGTILYAKWDSHFRESVEKTIP-----YSDKLFEMVLGP------AAYNVPLPKKSIQSGPLKISSVSEVMKESKQPASQLQKQKGDTPASATEASSSSIRERPPEEVAARLAQQEKQEQVKIESLAKSLEDALRQTASVTLQAIAAQNAAVQAVNAHSNILKAAMDNSEIAGEKKSAQWRTVEGALKERRKAVDEAADALLKAKEELEKMKSVIENAKKKEVAGAKPHITAAEGKLHNMIVDLDNVVKKVQAAQSEAKVVSQYHELVVQARDDFKRELDSITPEVLPGWKGMSVSDLADKLSTDDLNSLIAHAHRRIDQLNRELAEQKATEKQHITLALEKQKLEEKRAFDSAVAKALEHHRSEIQAEQDRKIEEVRDAMENEMRTQLRRQAAAHTDHLRDVLRVQEQELKSEFEQNLSEKLSEQELQFRRLSQEQVDNFTLDINTAYARLRGIEQAVQSHAVAEEEARKAHQLWLSVEALKYSMKTSSAETPTIPLGSAVEAIK--ANCSDNEFTQALTAAIPPESLTRGVYSEETLRARFYAVQKLARRVAMIDETRNSLYQYFLSYLQSLLLFPPQQL-KPPPELCPE--DINTFKLLSYASYCIEHGDLELAAKFVNQLKGESRRVAQDWLKEARMTLETKQIVEILTAYASAVGIGT 705
[Close]
BLAST of MICOS complex subunit MIC60 vs. Ensembl Human
Match: IMMT (inner membrane mitochondrial protein [Source:HGNC Symbol;Acc:HGNC:6047])

HSP 1 Score: 207.608 bits (527), Expect = 1.318e-56
Identity = 137/413 (33.17%), Postives = 230/413 (55.69%), Query Frame = 2 
Query:  965 IEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNV-SNW----TKKHTDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREAL----LKEREKMRASIDGWRM-------RVEGIEAAVEGRADEEILSREAQDMWVACHAL-HGVLTGNGATP--PLARYLNSFEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECDTEIDPESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSSKTAGS 2146
            ++ AQ  A++ +QY EL+ Q ++ FK+EL S+ P V   W         DKLS DDLN++I HAHRR+ QL   +AE ++ E   +  AL +Q+ +++ + +  V   LE  RS+   E   ++++++   E E+R  L RQA+AH +H+  +L++Q+ E+  +    + E L    L+ R   +  +D + +       R+ GIE AV+  A  E  +R+A  +W++  AL + + T +  TP  PL   + + +  A  S     Q    +IP  +L +GV ++  L  RF  ++++ RRVAMIDET  SL  Y +S+L+SL+L  P  L +   E+ PE  +I+T ++++ A   I   D +LA + +N LKG  R +  DW+ +AR+ LETK   + L++Y S+   G+
Sbjct:  246 VQAAQSEAKVVSQYHELVVQARDDFKRELDSITPEVLPGWKGMSVSDLADKLSTDDLNSLIAHAHRRIDQLNRELAEQKATEKQHITLALEKQKLEEKRAFDSAVAKALEHHRSEIQAEQDRKIEEVRDAMENEMRTQLRRQAAAHTDHLRDVLRVQEQELKSEFEQNLSEKLSEQELQFRRLSQEQVDNFTLDINTAYARLRGIEQAVQSHAVAEEEARKAHQLWLSVEALKYSMKTSSAETPTIPLGSAVEAIK--ANCSDNEFTQALTAAIPPESLTRGVYSEETLRARFYAVQKLARRVAMIDETRNSLYQYFLSYLQSLLLFPPQQL-KPPPELCPE--DINTFKLLSYASYCIEHGDLELAAKFVNQLKGESRRVAQDWLKEARMTLETKQIVEILTAYASAVGIGT 653
[Close]
BLAST of MICOS complex subunit MIC60 vs. Ensembl Human
Match: IMMT (inner membrane mitochondrial protein [Source:HGNC Symbol;Acc:HGNC:6047])

HSP 1 Score: 206.838 bits (525), Expect = 7.160e-56
Identity = 137/413 (33.17%), Postives = 230/413 (55.69%), Query Frame = 2 
Query:  965 IEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNV-SNW----TKKHTDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREAL----LKEREKMRASIDGWRM-------RVEGIEAAVEGRADEEILSREAQDMWVACHAL-HGVLTGNGATP--PLARYLNSFEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECDTEIDPESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSSKTAGS 2146
            ++ AQ  A++ +QY EL+ Q ++ FK+EL S+ P V   W         DKLS DDLN++I HAHRR+ QL   +AE ++ E   +  AL +Q+ +++ + +  V   LE  RS+   E   ++++++   E E+R  L RQA+AH +H+  +L++Q+ E+  +    + E L    L+ R   +  +D + +       R+ GIE AV+  A  E  +R+A  +W++  AL + + T +  TP  PL   + + +  A  S     Q    +IP  +L +GV ++  L  RF  ++++ RRVAMIDET  SL  Y +S+L+SL+L  P  L +   E+ PE  +I+T ++++ A   I   D +LA + +N LKG  R +  DW+ +AR+ LETK   + L++Y S+   G+
Sbjct:  334 VQAAQSEAKVVSQYHELVVQARDDFKRELDSITPEVLPGWKGMSVSDLADKLSTDDLNSLIAHAHRRIDQLNRELAEQKATEKQHITLALEKQKLEEKRAFDSAVAKALEHHRSEIQAEQDRKIEEVRDAMENEMRTQLRRQAAAHTDHLRDVLRVQEQELKSEFEQNLSEKLSEQELQFRRLSQEQVDNFTLDINTAYARLRGIEQAVQSHAVAEEEARKAHQLWLSVEALKYSMKTSSAETPTIPLGSAVEAIK--ANCSDNEFTQALTAAIPPESLTRGVYSEETLRARFYAVQKLARRVAMIDETRNSLYQYFLSYLQSLLLFPPQQL-KPPPELCPE--DINTFKLLSYASYCIEHGDLELAAKFVNQLKGESRRVAQDWLKEARMTLETKQIVEILTAYASAVGIGT 741
[Close]
BLAST of MICOS complex subunit MIC60 vs. Ensembl Human
Match: IMMT (inner membrane mitochondrial protein [Source:HGNC Symbol;Acc:HGNC:6047])

HSP 1 Score: 206.838 bits (525), Expect = 8.829e-56
Identity = 137/413 (33.17%), Postives = 230/413 (55.69%), Query Frame = 2 
Query:  965 IEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNV-SNW----TKKHTDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREAL----LKEREKMRASIDGWRM-------RVEGIEAAVEGRADEEILSREAQDMWVACHAL-HGVLTGNGATP--PLARYLNSFEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECDTEIDPESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSSKTAGS 2146
            ++ AQ  A++ +QY EL+ Q ++ FK+EL S+ P V   W         DKLS DDLN++I HAHRR+ QL   +AE ++ E   +  AL +Q+ +++ + +  V   LE  RS+   E   ++++++   E E+R  L RQA+AH +H+  +L++Q+ E+  +    + E L    L+ R   +  +D + +       R+ GIE AV+  A  E  +R+A  +W++  AL + + T +  TP  PL   + + +  A  S     Q    +IP  +L +GV ++  L  RF  ++++ RRVAMIDET  SL  Y +S+L+SL+L  P  L +   E+ PE  +I+T ++++ A   I   D +LA + +N LKG  R +  DW+ +AR+ LETK   + L++Y S+   G+
Sbjct:  344 VQAAQSEAKVVSQYHELVVQARDDFKRELDSITPEVLPGWKGMSVSDLADKLSTDDLNSLIAHAHRRIDQLNRELAEQKATEKQHITLALEKQKLEEKRAFDSAVAKALEHHRSEIQAEQDRKIEEVRDAMENEMRTQLRRQAAAHTDHLRDVLRVQEQELKSEFEQNLSEKLSEQELQFRRLSQEQVDNFTLDINTAYARLRGIEQAVQSHAVAEEEARKAHQLWLSVEALKYSMKTSSAETPTIPLGSAVEAIK--ANCSDNEFTQALTAAIPPESLTRGVYSEETLRARFYAVQKLARRVAMIDETRNSLYQYFLSYLQSLLLFPPQQL-KPPPELCPE--DINTFKLLSYASYCIEHGDLELAAKFVNQLKGESRRVAQDWLKEARMTLETKQIVEILTAYASAVGIGT 751
[Close]
BLAST of MICOS complex subunit MIC60 vs. Ensembl Celegans
Match: immt-1 (MICOS complex subunit MIC60-1 [Source:UniProtKB/Swiss-Prot;Acc:Q22505])

HSP 1 Score: 210.305 bits (534), Expect = 6.606e-58
Identity = 156/523 (29.83%), Postives = 261/523 (49.90%), Query Frame = 2 
Query:  590 NEVFSNKLSNQIDSVEAASTSVILHLMEYADKIQDHSQKLKRAIEDDGTTIPNPWEEVNES-NHLQQTAKTKSDKEMKRLELAIKQLELSINEGNHSEDLKSNPSIHTGQEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNVSNWTKKHTDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREALLKEREKMRASIDGWRMRVEGIEAAVEGRADEEILSREAQDMWVACHAL-----HGVLTGNGATP---PLARYLNSFEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILL-TPSHLIECDTEIDPESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTS 2128
            N+    KL   I S E          ++  + I +H+  LK+ ++D        WE V  +    +  A+  S +E+      I  L   +N+G       +NP +   QE  +  ++++ +  A + K++  + + NQYK+LI + +++F  E+ S+ PNV    K     L+ D+LNA+I HAH ++ QL+ ++++ +  E + +  AL EQR  DE  A  K+ +E+ R   +  +E +  L + +   E EL   L R ASAH+EH+ Q+++ Q+   + + +  V EA+L+ER      +     R+EGIE A+  R   +  +R A+  W+ACH L     HG   GN       PL   LN  +E   P    V    ++S PK A   G  T+  L  RF+++ ++ R+ A IDE   +L  Y  S+++SL L+  P      D  ID   +  D  ++++ A+  +   D D AIR++ LLKG P  +  DWI D R YLE++L A  L ++ +
Sbjct:  160 NQQLEEKLKIAIHSAEGKVRLATEAKLKTINAINEHASILKQTVDDAKHA---NWENVTSALQRAEAEARVDSGQEVDGRNY-IDNLRKIVNDGKRDSTTATNPLLLNAQETANKLSHQLDEINALVNKSRQESAVLNQYKDLIEKSRQQFALEMKSILPNVDIHAKDKN--LNEDELNALIAHAHLKVDQLRCQLSDQQVREELHISKALEEQRLADERIASEKLSIEMSRVGRQNELEIERALVESRSSWEGELENQLKRTASAHSEHLEQVIRTQRQLFEIEQNQKVEEAVLQERNLHSKQVGAALSRLEGIEEALGSRVALDNENRRAKQFWIACHNLIDTLKHGNKAGNNIDERRLPLNESLNLLKE-VNPEDEFV-NAIIDSFPKQATTVGTYTEQDLKNRFEQLYKIGRKTASIDENGGTLGAYFWSYVKSLFLVDMPQQYGNLDA-ID--VNNTDNYEILSRAKQYVHNGDLDKAIRVVQLLKGQPAHLARDWIVDTRSYLESRLLAQLLVAHAA 671
[Close]
BLAST of MICOS complex subunit MIC60 vs. Ensembl Celegans
Match: immt-2 (MICOS complex subunit MIC60-2 [Source:UniProtKB/Swiss-Prot;Acc:Q9XXN2])

HSP 1 Score: 130.568 bits (327), Expect = 3.332e-31
Identity = 135/558 (24.19%), Postives = 254/558 (45.52%), Query Frame = 2 
Query:  452 KESNGPESSQKESK-PFMNESVKKVPRTPSEKIKDDVEKEAERLKKLNEVFSNKLSNQIDSVEAASTSVILHLMEYADKIQDHSQKLKRAIE--DDGTTIPNPWEEVNESNHLQQTAKTKSDKEMKRLEL-AIKQLELSINEGNHSEDLKSNPSIHTGQEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNVSNWTKKHTDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQM--ELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREALLKEREKMRASIDGWRMRVEGIEAAVEGRADEEILSREAQDMWVACHALHG-VLTGN-------GATPPLARYLNS-FEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECDTEIDPESDEIDTNQVIASAELAIWRQDFDL-AIRLLNLLKGMPRVIVHDWITDAR 2077
            KE+  P+  +K+ + P++     K P  P E+               NE  +  L N +   E A+       +E    I+ H Q ++ AIE   DG      W+ V  + HL+     + D++ ++L   A+  L    N G   E  + NP +   +      +  + + +++++         + Y + + + + +F+ EL +++PN+ N+  +   K+   DL+ ++ HAH R+ QL  ++          +D+ L E+++   I A+ K  +  +L  E + K      E DK K   + EL RA       ++E + ++++ QK   D +H+  V EA+LKER    +++     ++ GIE A+ G    +I +R+++ MW+A   L G V+ GN       G   PL   + +        +S   ++    ++ K +  +G  T+  L  RF+K+ R+ RRVA ++E  A   +Y  SWL+S + +    L+      +  +  ++ N  + +    +W+      AIR+L L  G  R +  D+I DAR
Sbjct:  116 KETTEPKKIEKKPENPYIGA---KTPLNPQER---------------NEKLTESLKNHLTQAEKATKVATSAKLETIRAIEHHVQTIREAIEAGKDGD-----WDSVTVA-HLKAKRLAEKDEKAEKLARNAVADLVTEANLGGQGETTQLNPLVPISKATAEKLSNELDEMISNVKHVDSERIFVHDYSDRVAESRRKFQMELKAVHPNL-NY--EDGMKIKKADLHTILAHAHLRIDQLSQKL----------IDSKLNEEKRIQSIIAKKKEDLLEKLRLETNAKQAAVIPEFDKKKL--DAELARATAEIQKKYDEKLKEVVRTQKQLYDIEHAKDVDEAVLKERNLHSSAVGKALAQLAGIEKALSGHLQMDIENRKSKQMWLATQNLKGTVIFGNRASCCMEGRRAPLGDQMKTLLSCCGGGNSDEFVKTINTAMSKTSKVRGEYTEQDLNTRFNKVCRIGRRVAYVNEGGALAHLY--SWLKSSLTI---ELVPKKGANESLTPAVENNFTLLTRAEQLWKSGKKSDAIRVLQLTDGATRRVAADFIADAR 629
[Close]
BLAST of MICOS complex subunit MIC60 vs. Ensembl Fly
Match: Mitofilin (gene:FBgn0019960 transcript:FBtr0290271)

HSP 1 Score: 176.792 bits (447), Expect = 7.033e-46
Identity = 175/686 (25.51%), Postives = 327/686 (47.67%), Query Frame = 2 
Query:  188 QQSAFVPIFLGISSITLLGTGLSYY-YNDDFR---EKVAPYLPKRTKQFLDEYFDIP---ITDRIMKKWDSFNFFDKLSIKSNKMESFTSRFKGSKESNGPESSQKESKPFMNESVK------KVPRTPSEKIKDDVE-----KEAERLKKLNEVFSNKLSNQIDSVEAA-STSVILHLMEYADKI-------QDHSQKLKRAIEDDGTTIPNPWEEVNESNHLQQTAKTKSDKEMKRLELAIKQLELSINEGNHSEDLKSNPSIHTGQEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNVSNWTKKHTDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISA-EGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREALLKEREKMRASIDGWRMRVEGIEAAVEGRADEEILSREAQDMWVACHALHGVLTGNGATP---------PLARYLNSFEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECD-TEIDP-ESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSS 2131
            +++ F  + L +S +  +G  ++Y  Y+DDFR   EK  P      K  L E  + P   IT  +  + D       +   ++ ++S TS+  G       +   K+SK    E VK      K P  PSE  K + +       A       +   N L   +  +E A   S  L + EY   I        D  + + +A+E+   ++   W  +      + TA   +++  +  +  I   E++++    +++ K   ++    + L      +K +L    + +  A ++++Y   + + +  F  E+ S+ P +S   KK    LS +DL+  I+HA+  +   Q  +  L++   +RL  A+   R  ++  A   +++  LE ER K ++E Q+++  +    +  LR  L +QA AH +HI  ++  ++ ++ +     + + L  E+   +  + G   ++ G++AA+  RAD E  + +AQ +W AC AL   +    ATP         PL   +N+  + A+     ++   LES+PK A E+GV  ++ L +RF  ++RV RR+A++ E  A LP+Y +S+L+SL +L P + I  D  E  P +  ++DT  ++  A   + R DF  A++ +NLL+G  R I  +W+ +AR+ LET+ AA+ L ++ ++
Sbjct:   67 REAGFGKVVLFVSPLAAVGGVITYAKYDDDFRKLVEKNVPGAGSVIKVALQE--EPPFKGITKNVNDQIDKVK--SGIETVTSTVDSVTSKVTGLFGGGSGDDKSKKSKV---EPVKATPAEEKRPSKPSEVSKTEAKPVSKPAAAAAPAPAAKPKDNPLPRDVVELEKAIELSAQLAVKEYNVAIGVLKGFNDDVRKVVDKAVENGENSL---WTTLKNRASARDTAVATAERAAREAQEKIVACEIALSAAATAQNAKKVEAVRDKIKKLVDHIGNVKDELY---RHKDTASVSDKYWRNVEKARNYFIDEIESIFPGLSLADKKLN--LSKEDLDLFILHAYTHVLAYQKELQRLQTDGELRLKRAIDSVRGDNDSEALRAQLEYHLEAERRKLAVENQKKIFHIHAESDKLLRLQLKKQAEAHADHIKDIVAQRETDLTRSFKRELEDKLATEKANYKLQLAGMLGKLRGMDAALAERADAERTANQAQALWAACQALWASV--RAATPGVHYKDRLRPLKNEINAIAKVAKGDD--LVAAVLESVPKEAQERGVYPEDALRERFLNVERVARRLALVPEEGAGLPIYFLSYLQSLFILRPDNPISKDELENKPFDYSKLDTYDILNRARYHVDRSDFLQALKYMNLLQGASRKIAGEWMKEARLMLETQQAANTLMAHAAA 733
[Close]
BLAST of MICOS complex subunit MIC60 vs. Ensembl Fly
Match: Mitofilin (gene:FBgn0019960 transcript:FBtr0335199)

HSP 1 Score: 176.792 bits (447), Expect = 7.033e-46
Identity = 175/686 (25.51%), Postives = 327/686 (47.67%), Query Frame = 2 
Query:  188 QQSAFVPIFLGISSITLLGTGLSYY-YNDDFR---EKVAPYLPKRTKQFLDEYFDIP---ITDRIMKKWDSFNFFDKLSIKSNKMESFTSRFKGSKESNGPESSQKESKPFMNESVK------KVPRTPSEKIKDDVE-----KEAERLKKLNEVFSNKLSNQIDSVEAA-STSVILHLMEYADKI-------QDHSQKLKRAIEDDGTTIPNPWEEVNESNHLQQTAKTKSDKEMKRLELAIKQLELSINEGNHSEDLKSNPSIHTGQEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNVSNWTKKHTDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISA-EGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREALLKEREKMRASIDGWRMRVEGIEAAVEGRADEEILSREAQDMWVACHALHGVLTGNGATP---------PLARYLNSFEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECD-TEIDP-ESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSS 2131
            +++ F  + L +S +  +G  ++Y  Y+DDFR   EK  P      K  L E  + P   IT  +  + D       +   ++ ++S TS+  G       +   K+SK    E VK      K P  PSE  K + +       A       +   N L   +  +E A   S  L + EY   I        D  + + +A+E+   ++   W  +      + TA   +++  +  +  I   E++++    +++ K   ++    + L      +K +L    + +  A ++++Y   + + +  F  E+ S+ P +S   KK    LS +DL+  I+HA+  +   Q  +  L++   +RL  A+   R  ++  A   +++  LE ER K ++E Q+++  +    +  LR  L +QA AH +HI  ++  ++ ++ +     + + L  E+   +  + G   ++ G++AA+  RAD E  + +AQ +W AC AL   +    ATP         PL   +N+  + A+     ++   LES+PK A E+GV  ++ L +RF  ++RV RR+A++ E  A LP+Y +S+L+SL +L P + I  D  E  P +  ++DT  ++  A   + R DF  A++ +NLL+G  R I  +W+ +AR+ LET+ AA+ L ++ ++
Sbjct:   67 REAGFGKVVLFVSPLAAVGGVITYAKYDDDFRKLVEKNVPGAGSVIKVALQE--EPPFKGITKNVNDQIDKVK--SGIETVTSTVDSVTSKVTGLFGGGSGDDKSKKSKV---EPVKATPAEEKRPSKPSEVSKTEAKPVSKPAAAAAPAPAAKPKDNPLPRDVVELEKAIELSAQLAVKEYNVAIGVLKGFNDDVRKVVDKAVENGENSL---WTTLKNRASARDTAVATAERAAREAQEKIVACEIALSAAATAQNAKKVEAVRDKIKKLVDHIGNVKDELY---RHKDTASVSDKYWRNVEKARNYFIDEIESIFPGLSLADKKLN--LSKEDLDLFILHAYTHVLAYQKELQRLQTDGELRLKRAIDSVRGDNDSEALRAQLEYHLEAERRKLAVENQKKIFHIHAESDKLLRLQLKKQAEAHADHIKDIVAQRETDLTRSFKRELEDKLATEKANYKLQLAGMLGKLRGMDAALAERADAERTANQAQALWAACQALWASV--RAATPGVHYKDRLRPLKNEINAIAKVAKGDD--LVAAVLESVPKEAQERGVYPEDALRERFLNVERVARRLALVPEEGAGLPIYFLSYLQSLFILRPDNPISKDELENKPFDYSKLDTYDILNRARYHVDRSDFLQALKYMNLLQGASRKIAGEWMKEARLMLETQQAANTLMAHAAA 733
[Close]
BLAST of MICOS complex subunit MIC60 vs. Ensembl Fly
Match: Mitofilin (gene:FBgn0019960 transcript:FBtr0335200)

HSP 1 Score: 171.014 bits (432), Expect = 5.907e-44
Identity = 175/693 (25.25%), Postives = 328/693 (47.33%), Query Frame = 2 
Query:  188 QQSAFVPIFLGISSITLLGTGLSYY-YNDDFR---EKVAPYLPKRTKQFLDEYFDIP---ITDRIMKKWDSFNFFDKLSIKSNKMESFTSRFKGSKESNGPESSQKESKPFMNESVK------KVPRTPSEKIKDDVE-----KEAERLKKLNEVFSNKLSNQIDSVEAA-STSVILHLMEYADKI-------QDHSQKLKRAIEDDGTTIPNPWEEVNESNHLQQTAKTKSDKEMKRLELAIKQLELSINEGNHSEDLKSNPSIHTGQEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNVSNWTKKHTDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISA-EGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREALLKEREKMRASIDGWRMRVEGIEAAV-------EGRADEEILSREAQDMWVACHALHGVLTGNGATP---------PLARYLNSFEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECD-TEIDP-ESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSS 2131
            +++ F  + L +S +  +G  ++Y  Y+DDFR   EK  P      K  L E  + P   IT  +  + D       +   ++ ++S TS+  G       +   K+SK    E VK      K P  PSE  K + +       A       +   N L   +  +E A   S  L + EY   I        D  + + +A+E+   ++   W  +      + TA   +++  +  +  I   E++++    +++ K   ++    + L      +K +L    + +  A ++++Y   + + +  F  E+ S+ P +S   KK    LS +DL+  I+HA+  +   Q  +  L++   +RL  A+   R  ++  A   +++  LE ER K ++E Q+++  +    +  LR  L +QA AH +HI  ++  ++ ++ +     + + L  E+   +  + G   ++ G++AA+       + RAD E  + +AQ +W AC AL   +    ATP         PL   +N+  + A+     ++   LES+PK A E+GV  ++ L +RF  ++RV RR+A++ E  A LP+Y +S+L+SL +L P + I  D  E  P +  ++DT  ++  A   + R DF  A++ +NLL+G  R I  +W+ +AR+ LET+ AA+ L ++ ++
Sbjct:   67 REAGFGKVVLFVSPLAAVGGVITYAKYDDDFRKLVEKNVPGAGSVIKVALQE--EPPFKGITKNVNDQIDKVK--SGIETVTSTVDSVTSKVTGLFGGGSGDDKSKKSKV---EPVKATPAEEKRPSKPSEVSKTEAKPVSKPAAAAAPAPAAKPKDNPLPRDVVELEKAIELSAQLAVKEYNVAIGVLKGFNDDVRKVVDKAVENGENSL---WTTLKNRASARDTAVATAERAAREAQEKIVACEIALSAAATAQNAKKVEAVRDKIKKLVDHIGNVKDELY---RHKDTASVSDKYWRNVEKARNYFIDEIESIFPGLSLADKKLN--LSKEDLDLFILHAYTHVLAYQKELQRLQTDGELRLKRAIDSVRGDNDSEALRAQLEYHLEAERRKLAVENQKKIFHIHAESDKLLRLQLKKQAEAHADHIKDIVAQRETDLTRSFKRELEDKLATEKANYKLQLAGMLGKLRGMDAALAEIEDEFQERADAERTANQAQALWAACQALWASV--RAATPGVHYKDRLRPLKNEINAIAKVAKGDD--LVAAVLESVPKEAQERGVYPEDALRERFLNVERVARRLALVPEEGAGLPIYFLSYLQSLFILRPDNPISKDELENKPFDYSKLDTYDILNRARYHVDRSDFLQALKYMNLLQGASRKIAGEWMKEARLMLETQQAANTLMAHAAA 740
[Close]
BLAST of MICOS complex subunit MIC60 vs. Ensembl Zebrafish
Match: immt (inner membrane protein, mitochondrial (mitofilin) [Source:ZFIN;Acc:ZDB-GENE-030131-5417])

HSP 1 Score: 214.927 bits (546), Expect = 8.255e-59
Identity = 148/505 (29.31%), Postives = 279/505 (55.25%), Query Frame = 2 
Query:  686 IQDHSQKLKRAIEDDGTTIPNPWEEVNESNHLQQTAKTKSDKEMKRLELAIKQLELSINEGNHSEDLKSNPSIHTGQEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNV-SNWTKKHTDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREALLKE----REKMRASIDGWRM-------RVEGIEAAVEGRADEEILSREAQDMWVACHALHGVLTGNGA---TPPLARYLNSFEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECDTEIDP---ESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSSKTAGS 2146
            I  H+ KL+ A++ +        + +NE+ + +  A   + + + + +  +++L   I++   S+   + P I   +E L S    + + +  ++ AQ  A+I +QY EL+++ + +F+QEL+++ P + +NW K  + KLS DDLN++I HAHRR+ QL   +AE    E I ++ AL +Q+ +D+ + E  V   LE  R    +E ++++ ++++  E E+R  L RQA+AH +H+  +LK+Q+ E+ ++    +   ++++    R   +  +D + +       R++GIE A++     E  +R+A  +W++  AL+  L   GA   T PL   + + +E+   +     Q    +IP+ +L +G+ ++  L  RF  I+R+ RRVA+IDET  SL  Y +S+L+S++L       E D E  P     +++DT +++A A  +I R D +LA + +N L+G  + +  DW+ +AR+ LETK     LS+Y ++   G+
Sbjct:  258 IAAHTDKLREAMDSETPPDEKSTQALNEALNERARAVDDAGEALFKAKGELEKLRSVIDKAKQSKIDSARPQILAAEENLHSMIVDLDKVVTKVQTAQSEAKIVSQYSELVNEAKAQFQQELANITPEIQANW-KGLSGKLSADDLNSLIAHAHRRIDQLNRELAEQRVREQIHIEVALEQQKLEDQKAQERAVISALEHSREDMRLEQEKKVQEVREVMEAEMRTQLRRQAAAHTDHLRDVLKVQEQELREEAQEILNSKMMEQETHYRRLTQEQLDTFTLDMNAAYARLKGIEEAIDSHVIAEEEARKAHQLWLSVEALNYTLKSAGADSPTEPLEGAVRAIKESC--AENEFAQALAIAIPEESLNRGIYSEASLRARFYDIRRLARRVALIDETRNSLYQYFLSYLQSVLLF------ERDQEAPPAKLAPEDLDTFKLLAYATYSIERGDLELAAKFVNQLRGESQRVAQDWLKEARLTLETKQVISLLSAYANAVGLGT 753
[Close]
BLAST of MICOS complex subunit MIC60 vs. Ensembl Xenopus
Match: stau1 (staufen double-stranded RNA binding protein 1 [Source:Xenbase;Acc:XB-GENE-920408])

HSP 1 Score: 221.09 bits (562), Expect = 4.572e-61
Identity = 188/658 (28.57%), Postives = 341/658 (51.82%), Query Frame = 2 
Query:  263 YNDDFREKVAPYLPKRTKQFLDEYFDI------PITDRIMKKWDSFNFFDKLSIKSNKMESFTSRFKGSKESNGP--ESSQKESKPFMNESVKKVPRTPSEKIKDDV----EKEAERLKKLNEVFSNKLSNQIDSVEAASTSVILHLMEYADKIQD-HSQKLKRAIEDDGTTIPNP---WEEVNESNHLQQTAKTKSDKEMKRLELAIKQLELSINEGNHSEDLKSNPSIHTGQEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNVSNWTKKHTDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREAL----LKEREKMRASIDGWRM-------RVEGIEAAVEGRADEEILSREAQDMWVACHALHGVL---TGNGATPPLARYLNSFEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECDTEIDPESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSSKTAGS 2146
            ++  FRE V   +P     + D+ FD+      P +  + KK           +KS  ++  +S  +  KES  P  E  ++  K   +E+  K+   P E++   +    ++E ER+K +     + LSN      A  T   +   E A +  D H+QKL+ A+++   +       W ++ ++  ++  A  ++   + + +  I++++  I +   S    + P I + +E L      +   +  ++ AQ  A+I  QY EL+   +E F++EL S+ P V    K  T +LS DDLN++I HAHRR+ QL  ++AE    E   ++AAL +Q+ +D+ + E  V   LE  R++  +E +++ +++++  E E+R  L RQA+AH++H+  +L +Q+ E+  +   ++ E L    ++ +   +  +DG+ +       R++GIE AVEG A  E  +R+A  +W++  AL   +    G+  T PL   +     +   S+    +    +IP  +L +GV ++  L  RF  ++++ RRVA+IDET  SL  Y +S+L+SL++  P  L +  TE+ P  D++DT +++  A   + R D +LA + +N LKG  R +VHDW+ +AR+ LET+   D LS+Y S+   G+
Sbjct:   67 WDPRFRENVEKTIP-----YSDKLFDLALGPPAPASLPVPKK----------PLKSGPLQ-ISSVSEVMKESKMPKKEKVEEHCKECEHEATHKLKERPPEEVAARLVQQDKEEQERIKSIAAALEDALSNT-----ARVTLQAIGTQESAVQAVDFHAQKLREAMDETQISADKKSLQWRDLEDALKVRSKAVDEAADSLLKAKEEIERMQSIIADSKKSLISGAKPHIISAEENLHRMIVDLDNVVKKVQAAQSEAKIVAQYHELVSLAREEFQRELDSITPEVQPGWKGLTGRLSADDLNSLIAHAHRRIDQLHKQLAEYRVKEQQHIEAALEKQKLEDKKALEAAVTKALEHHRAEIHLEQEKKAEEVREVMEAEMRTQLRRQAAAHSDHLRDVLNVQEQELKAEFQQSLSEKLSDQEMQFKRLAQEQLDGFTLDMNTAYSRLKGIEQAVEGHAAAEEEARKAHHLWLSVEALKFTMKTAAGDSPTEPLETAVQGIRSSC--SNNEFTEALTGAIPHESLHRGVYSEESLRARFYSVRKLARRVALIDETRNSLYQYFLSYLQSLLVFEPKEL-KPPTELSP--DDLDTFKLLCYASFCVERGDLELAAKFINQLKGESRRVVHDWLNEARLTLETRQVIDILSAYASAVGLGT 698
[Close]
BLAST of MICOS complex subunit MIC60 vs. Ensembl Xenopus
Match: stau1 (staufen double-stranded RNA binding protein 1 [Source:Xenbase;Acc:XB-GENE-920408])

HSP 1 Score: 219.164 bits (557), Expect = 1.274e-60
Identity = 164/571 (28.72%), Postives = 305/571 (53.42%), Query Frame = 2 
Query:  503 NESVKKVPRTPSEKIKDDV----EKEAERLKK--LNEVFSNKLSNQIDSVEAASTSVILHLMEYADKIQDHSQKLKRAIEDDGTTIPNP---WEEVNESNHLQQTAKTKSDKEMKRLELAIKQLELSINEGNHSEDLKSNPSIHTGQEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNVSNWTKKHTDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREAL----LKEREKMRASIDGWRM-------RVEGIEAAVEGRADEEILSREAQDMWVACHALHGVL---TGNGATPPLARYLNSFEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECDTEIDPESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSSKTAGS 2146
            +E+  K+   P E++   +    ++E ER+K   L +  SN     + ++    ++V          +  H+QKL+ A+++   +       W ++ ++  ++  A  ++   + + +  I++++  I +   S    + P I + +E L      +   +  ++ AQ  A+I  QY EL+   +E F++EL S+ P V    K  T +LS DDLN++I HAHRR+ QL  ++AE    E   ++AAL +Q+ +D+ + E  V   LE  R++  +E +++ +++++  E E+R  L RQA+AH++H+  +L +Q+ E+  +   ++ E L    ++ +   +  +DG+ +       R++GIE AVEG A  E  +R+A  +W++  AL   +    G+  T PL   +     +   S+    +    +IP  +L +GV ++  L  RF  ++++ RRVA+IDET  SL  Y +S+L+SL++  P  L +  TE+ P  D++DT +++  A   + R D +LA + +N LKG  R +VHDW+ +AR+ LET+   D LS+Y S+   G+
Sbjct:  112 HEATHKLKERPPEEVAARLVQQDKEEQERIKSAALEDALSNTARVTLQAIGTQESAV--------QAVDFHAQKLREAMDETQISADKKSLQWRDLEDALKVRSKAVDEAADSLLKAKEEIERMQSIIADSKKSLISGAKPHIISAEENLHRMIVDLDNVVKKVQAAQSEAKIVAQYHELVSLAREEFQRELDSITPEVQPGWKGLTGRLSADDLNSLIAHAHRRIDQLHKQLAEYRVKEQQHIEAALEKQKLEDKKALEAAVTKALEHHRAEIHLEQEKKAEEVREVMEAEMRTQLRRQAAAHSDHLRDVLNVQEQELKAEFQQSLSEKLSDQEMQFKRLAQEQLDGFTLDMNTAYSRLKGIEQAVEGHAAAEEEARKAHHLWLSVEALKFTMKTAAGDSPTEPLETAVQGIRSSC--SNNEFTEALTGAIPHESLHRGVYSEESLRARFYSVRKLARRVALIDETRNSLYQYFLSYLQSLLVFEPKEL-KPPTELSP--DDLDTFKLLCYASFCVERGDLELAAKFINQLKGESRRVVHDWLNEARLTLETRQVIDILSAYASAVGLGT 669
[Close]
BLAST of MICOS complex subunit MIC60 vs. Ensembl Xenopus
Match: stau1 (staufen double-stranded RNA binding protein 1 [Source:Xenbase;Acc:XB-GENE-920408])

HSP 1 Score: 218.779 bits (556), Expect = 5.320e-60
Identity = 164/550 (29.82%), Postives = 297/550 (54.00%), Query Frame = 2 
Query:  563 KEAERLKKLNEVFSNKLSNQIDSVEAASTSVILHLMEYADKIQD-HSQKLKRAIEDDGTTIPNP---WEEVNESNHLQQTAKTKSDKEMKRLELAIKQLELSINEGNHSEDLKSNPSIHTGQEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNVS-NW---TKKHTDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREAL----LKEREKMRASIDGWRM-------RVEGIEAAVEGRADEEILSREAQDMWVACHALHGVL---TGNGATPPLARYLNSFEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECDTEIDPESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSSKTAGS 2146
            +E ER+K +     + LSN      A  T   +   E A +  D H+QKL+ A+++   +       W ++ ++  ++  A  ++   + + +  I++++  I +   S    + P I + +E L      +   +  ++ AQ  A+I  QY EL+   +E F++EL S+ P V   W   +K  + +LS DDLN++I HAHRR+ QL  ++AE    E   ++AAL +Q+ +D+ + E  V   LE  R++  +E +++ +++++  E E+R  L RQA+AH++H+  +L +Q+ E+  +   ++ E L    ++ +   +  +DG+ +       R++GIE AVEG A  E  +R+A  +W++  AL   +    G+  T PL   +     +   S+    +    +IP  +L +GV ++  L  RF  ++++ RRVA+IDET  SL  Y +S+L+SL++  P  L +  TE+ P  D++DT +++  A   + R D +LA + +N LKG  R +VHDW+ +AR+ LET+   D LS+Y S+   G+
Sbjct:  198 EEQERIKSIAAALEDALSNT-----ARVTLQAIGTQESAVQAVDFHAQKLREAMDETQISADKKSLQWRDLEDALKVRSKAVDEAADSLLKAKEEIERMQSIIADSKKSLISGAKPHIISAEENLHRMIVDLDNVVKKVQAAQSEAKIVAQYHELVSLAREEFQRELDSITPEVQPGWKGLSKSCSGRLSADDLNSLIAHAHRRIDQLHKQLAEYRVKEQQHIEAALEKQKLEDKKALEAAVTKALEHHRAEIHLEQEKKAEEVREVMEAEMRTQLRRQAAAHSDHLRDVLNVQEQELKAEFQQSLSEKLSDQEMQFKRLAQEQLDGFTLDMNTAYSRLKGIEQAVEGHAAAEEEARKAHHLWLSVEALKFTMKTAAGDSPTEPLETAVQGIRSSC--SNNEFTEALTGAIPHESLHRGVYSEESLRARFYSVRKLARRVALIDETRNSLYQYFLSYLQSLLVFEPKEL-KPPTELSP--DDLDTFKLLCYASFCVERGDLELAAKFINQLKGESRRVVHDWLNEARLTLETRQVIDILSAYASAVGLGT 737
[Close]
BLAST of MICOS complex subunit MIC60 vs. Ensembl Xenopus
Match: stau1 (staufen double-stranded RNA binding protein 1 [Source:Xenbase;Acc:XB-GENE-920408])

HSP 1 Score: 217.624 bits (553), Expect = 1.547e-59
Identity = 164/550 (29.82%), Postives = 297/550 (54.00%), Query Frame = 2 
Query:  563 KEAERLKKLNEVFSNKLSNQIDSVEAASTSVILHLMEYADKIQD-HSQKLKRAIEDDGTTIPNP---WEEVNESNHLQQTAKTKSDKEMKRLELAIKQLELSINEGNHSEDLKSNPSIHTGQEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNVS-NW---TKKHTDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREAL----LKEREKMRASIDGWRM-------RVEGIEAAVEGRADEEILSREAQDMWVACHALHGVL---TGNGATPPLARYLNSFEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECDTEIDPESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSSKTAGS 2146
            +E ER+K +     + LSN      A  T   +   E A +  D H+QKL+ A+++   +       W ++ ++  ++  A  ++   + + +  I++++  I +   S    + P I + +E L      +   +  ++ AQ  A+I  QY EL+   +E F++EL S+ P V   W   +K  + +LS DDLN++I HAHRR+ QL  ++AE    E   ++AAL +Q+ +D+ + E  V   LE  R++  +E +++ +++++  E E+R  L RQA+AH++H+  +L +Q+ E+  +   ++ E L    ++ +   +  +DG+ +       R++GIE AVEG A  E  +R+A  +W++  AL   +    G+  T PL   +     +   S+    +    +IP  +L +GV ++  L  RF  ++++ RRVA+IDET  SL  Y +S+L+SL++  P  L +  TE+ P  D++DT +++  A   + R D +LA + +N LKG  R +VHDW+ +AR+ LET+   D LS+Y S+   G+
Sbjct:  222 EEQERIKSIAAALEDALSNT-----ARVTLQAIGTQESAVQAVDFHAQKLREAMDETQISADKKSLQWRDLEDALKVRSKAVDEAADSLLKAKEEIERMQSIIADSKKSLISGAKPHIISAEENLHRMIVDLDNVVKKVQAAQSEAKIVAQYHELVSLAREEFQRELDSITPEVQPGWKGLSKSCSGRLSADDLNSLIAHAHRRIDQLHKQLAEYRVKEQQHIEAALEKQKLEDKKALEAAVTKALEHHRAEIHLEQEKKAEEVREVMEAEMRTQLRRQAAAHSDHLRDVLNVQEQELKAEFQQSLSEKLSDQEMQFKRLAQEQLDGFTLDMNTAYSRLKGIEQAVEGHAAAEEEARKAHHLWLSVEALKFTMKTAAGDSPTEPLETAVQGIRSSC--SNNEFTEALTGAIPHESLHRGVYSEESLRARFYSVRKLARRVALIDETRNSLYQYFLSYLQSLLVFEPKEL-KPPTELSP--DDLDTFKLLCYASFCVERGDLELAAKFINQLKGESRRVVHDWLNEARLTLETRQVIDILSAYASAVGLGT 761
[Close]
BLAST of MICOS complex subunit MIC60 vs. Ensembl Xenopus
Match: stau1 (staufen double-stranded RNA binding protein 1 [Source:Xenbase;Acc:XB-GENE-920408])

HSP 1 Score: 214.157 bits (544), Expect = 2.577e-58
Identity = 165/551 (29.95%), Postives = 297/551 (53.90%), Query Frame = 2 
Query:  563 KEAERLKKLNEVFSNKLSNQIDSVEAASTSVILHLMEYADKIQD-HSQKLKRAIEDDGTTIPNP---WEEVNESNHLQQTAKTKSDKEMKRLELAIKQLELSINEGNHSEDLKSNPSIHTGQEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNVS-NWTK-KHTD---KLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREAL----LKEREKMRASIDGWRM-------RVEGIEAAVEGRADEEILSREAQDMWVACHALHGVL---TGNGATPPLARYLNSFEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECDTEIDPESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSSKTAGS 2146
            +E ER+K +     + LSN      A  T   +   E A +  D H+QKL+ A+++   +       W ++ ++  ++  A  ++   + + +  I++++  I +   S    + P I + +E L      +   +  ++ AQ  A+I  QY EL+   +E F++EL S+ P V   W   K +D   +LS DDLN++I HAHRR+ QL  ++AE    E   ++AAL +Q+ +D+ + E  V   LE  R++  +E +++ +++++  E E+R  L RQA+AH++H+  +L +Q+ E+  +   ++ E L    ++ +   +  +DG+ +       R++GIE AVEG A  E  +R+A  +W++  AL   +    G+  T PL   +     +   S+    +    +IP  +L +GV ++  L  RF  ++++ RRVA+IDET  SL  Y +S+L+SL++  P  L +  TE+ P  D++DT +++  A   + R D +LA + +N LKG  R +VHDW+ +AR+ LET+   D LS+Y S+   G+
Sbjct:  222 EEQERIKSIAAALEDALSNT-----ARVTLQAIGTQESAVQAVDFHAQKLREAMDETQISADKKSLQWRDLEDALKVRSKAVDEAADSLLKAKEEIERMQSIIADSKKSLISGAKPHIISAEENLHRMIVDLDNVVKKVQAAQSEAKIVAQYHELVSLAREEFQRELDSITPEVQPGWKGLKISDIAGRLSADDLNSLIAHAHRRIDQLHKQLAEYRVKEQQHIEAALEKQKLEDKKALEAAVTKALEHHRAEIHLEQEKKAEEVREVMEAEMRTQLRRQAAAHSDHLRDVLNVQEQELKAEFQQSLSEKLSDQEMQFKRLAQEQLDGFTLDMNTAYSRLKGIEQAVEGHAAAEEEARKAHHLWLSVEALKFTMKTAAGDSPTEPLETAVQGIRSSC--SNNEFTEALTGAIPHESLHRGVYSEESLRARFYSVRKLARRVALIDETRNSLYQYFLSYLQSLLVFEPKEL-KPPTELSP--DDLDTFKLLCYASFCVERGDLELAAKFINQLKGESRRVVHDWLNEARLTLETRQVIDILSAYASAVGLGT 762
[Close]
BLAST of MICOS complex subunit MIC60 vs. Ensembl Mouse
Match: Immt (inner membrane protein, mitochondrial [Source:MGI Symbol;Acc:MGI:1923864])

HSP 1 Score: 211.46 bits (537), Expect = 5.555e-58
Identity = 170/629 (27.03%), Postives = 311/629 (49.44%), Query Frame = 2 
Query:  359 IMKKWDSFNFFDKLSIKSNKMESFTSRFKGSKESNGPESSQKESKPFMNESVK-----------KVPRTPSEKIKDDVEKEAERLKKLNEVFSNKLSNQIDSVEAASTSVILHLMEYADKIQDHSQKLKRAIEDD---GTTIPNPWEEVNESNHLQQTAKTKSDKEMKRLELAIKQLELSINEGNHSEDLKSNPSIHTGQEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNVS-NWTKKH----TDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREAL----LKEREKMRASIDGWRM-------RVEGIEAAVEGRADEEILSREAQDMWVACHAL-HGVLTGNGATPPLARYLNSFEEA--AQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECDTEIDPESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSSKTAGS 2146
            +  KWDS +F + +     K   ++ +  G    + P +     KP  +  +K           K+P   S+K K D    A   K L +  +   S  + ++ A + +V          ++ HS  LK A+++    G      W  V  +   ++ A  ++   + + +  +++++  I +    E   + P I   +  L +    +   +  ++ AQ  A++ +QY EL+ Q ++ F++EL S+ P+++  W          KLS DDLN++I HAHRR+ QL   +A+ ++ E   ++ AL + + +++ + +  V   LE  RS+   E   ++++++   E E+R  L RQA+AH +H+  +LK+Q+ E+  +    + E L    L+ R + +  +D + +       R+ GIE AV+  A  E  +R+A  +W++  AL + + T +   P +   L S  EA     S     Q    +IP  +L +GV ++  L  RF  ++++ RRVAMIDET  SL  Y +S+L+SL+L  P  L +   E+ PE  +I+T ++++ A   I   D +LA + +N LKG  R +  DW+ +AR+ LETK   + L++Y S+   G+
Sbjct:   63 LYAKWDS-HFRESV----EKTIPYSDKLFGMVLGSAPYTVPLPKKPVQSGPLKISSVSEVMKDSKLPVAQSQKTKGDTPASAALAKSLEDALNRTSSVTLQTITAQNAAV--------QAVKAHSNILKTAMDNSEIAGEKKSAQWRTVEGALKERRKAVDEAADALLKAKEELEKMKTIIEDAKKREIAGATPHITAAEGRLHNMIVDLDNVVKKVQAAQSEAKVVSQYHELVVQARDDFRKELDSITPDITPGWKGMSISDLAGKLSTDDLNSLIAHAHRRIDQLNRELAQQKATEKQHIELALEKHKLEEKRTFDSAVAKALEHHRSEIQAEQDRKVEEVRDAMENEMRTQLRRQAAAHTDHLRDVLKVQEQELKYEFEQGLSEKLSEQELEFRRRSQEQMDSFTLDINTAYARLRGIEQAVQSHAVAEEEARKAHQLWLSVEALKYSMKTSSAEMPTIP--LGSAVEAIRVNCSDNEFTQALTAAIPPESLTRGVYSEETLRARFYAVQKLARRVAMIDETRNSLYQYFLSYLQSLLLFPPKQL-KPPAELYPE--DINTFKLLSYASYCIEHGDLELAAKFVNQLKGESRRVAQDWLKEARMTLETKQIVEILTAYASAVGIGT 673
[Close]
BLAST of MICOS complex subunit MIC60 vs. Ensembl Mouse
Match: Immt (inner membrane protein, mitochondrial [Source:MGI Symbol;Acc:MGI:1923864])

HSP 1 Score: 210.305 bits (534), Expect = 1.878e-57
Identity = 182/672 (27.08%), Postives = 329/672 (48.96%), Query Frame = 2 
Query:  209 IFLGISSITLLGTGLSYYYNDDFREKVAPYLPKRTKQFLDEYFDIPITDRIMKKWDSFNFFDKLSIKSNKMESFTSRFKGSKESNG--PESSQKESKPFMNESVK-------KVPRTPSEKIKDDVEKEAERLKKLNEVFSNKLSNQIDSVEAASTSVILHLMEYADKIQDHSQKLKRAIEDD---GTTIPNPWEEVNESNHLQQTAKTKSDKEMKRLELAIKQLELSINEGNHSEDLKSNPSIHTGQEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNVSNWTKKHTDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREAL----LKEREKMRASIDGWRM-------RVEGIEAAVEGRADEEILSREAQDMWVACHAL-HGVLTGNGATPPLARYLNSFEEA--AQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECDTEIDPESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSSKTAGS 2146
            +F+G     + GT L   ++  FRE V   +P   K F       P T  + KK        K+S  S  M+        S+++ G  P S+  ++      +V+       + P T   K   +    A   K L +  +   S  + ++ A + +V          ++ HS  LK A+++    G      W  V  +   ++ A  ++   + + +  +++++  I +    E   + P I   +  L +    +   +  ++ AQ  A++ +QY EL+ Q ++ F++EL S+ P+++   K  T KLS DDLN++I HAHRR+ QL   +A+ ++ E   ++ AL + + +++ + +  V   LE  RS+   E   ++++++   E E+R  L RQA+AH +H+  +LK+Q+ E+  +    + E L    L+ R + +  +D + +       R+ GIE AV+  A  E  +R+A  +W++  AL + + T +   P +   L S  EA     S     Q    +IP  +L +GV ++  L  RF  ++++ RRVAMIDET  SL  Y +S+L+SL+L  P  L +   E+ PE  +I+T ++++ A   I   D +LA + +N LKG  R +  DW+ +AR+ LETK   + L++Y S+   G+
Sbjct:   52 LFVGGG---IGGTILYAKWDSHFRESVEKTIPYSDKLFGMVLGSAPYTVPLPKKPVQSGPL-KISSVSEVMKDSKLPVAQSQKTKGDTPASAAGDTLSVPAPAVQHEDTIKTECPNTNEGKSTSETTALA---KSLEDALNRTSSVTLQTITAQNAAV--------QAVKAHSNILKTAMDNSEIAGEKKSAQWRTVEGALKERRKAVDEAADALLKAKEELEKMKTIIEDAKKREIAGATPHITAAEGRLHNMIVDLDNVVKKVQAAQSEAKVVSQYHELVVQARDDFRKELDSITPDITPGWKGMTGKLSTDDLNSLIAHAHRRIDQLNRELAQQKATEKQHIELALEKHKLEEKRTFDSAVAKALEHHRSEIQAEQDRKVEEVRDAMENEMRTQLRRQAAAHTDHLRDVLKVQEQELKYEFEQGLSEKLSEQELEFRRRSQEQMDSFTLDINTAYARLRGIEQAVQSHAVAEEEARKAHQLWLSVEALKYSMKTSSAEMPTIP--LGSAVEAIRVNCSDNEFTQALTAAIPPESLTRGVYSEETLRARFYAVQKLARRVAMIDETRNSLYQYFLSYLQSLLLFPPKQL-KPPAELYPE--DINTFKLLSYASYCIEHGDLELAAKFVNQLKGESRRVAQDWLKEARMTLETKQIVEILTAYASAVGIGT 703
[Close]
BLAST of MICOS complex subunit MIC60 vs. Ensembl Mouse
Match: Immt (inner membrane protein, mitochondrial [Source:MGI Symbol;Acc:MGI:1923864])

HSP 1 Score: 202.216 bits (513), Expect = 2.664e-54
Identity = 145/509 (28.49%), Postives = 268/509 (52.65%), Query Frame = 2 
Query:  686 IQDHSQKLKRAIEDD---GTTIPNPWEEVNESNHLQQTAKTKSDKEMKRLELAIKQLELSINEGNHSEDLKSNPSIHTGQEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNVSNWTKKHT-----DKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREAL----LKEREKMRASIDGWRM-------RVEGIEAAVEGRADEEILSREAQDMWVACHAL-HGVLTGNGATP--PLARYLNSFEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECDTEIDPESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSSKTAGS 2146
            ++ HS  LK A+++    G      W  V  +   ++ A  ++   + + +  +++++  I +    E   + P I   +  L +    +   +  ++ AQ  A++ +QY EL+ Q ++ F++EL S+ P+++   K  +      KLS DDLN++I HAHRR+ QL   +A+ ++ E   ++ AL + + +++ + +  V   LE  RS+   E   ++++++   E E+R  L RQA+AH +H+  +LK+Q+ E+  +    + E L    L+ R + +  +D + +       R+ GIE AV+  A  E  +R+A  +W++  AL + + T +   P  PL   + +       S     Q    +IP  +L +GV ++  L  RF  ++++ RRVAMIDET  SL  Y +S+L+SL+L  P  L +   E+ PE  +I+T ++++ A   I   D +LA + +N LKG  R +  DW+ +AR+ LETK   + L++Y S+   G+
Sbjct:  248 VKAHSNILKTAMDNSEIAGEKKSAQWRTVEGALKERRKAVDEAADALLKAKEELEKMKTIIEDAKKREIAGATPHITAAEGRLHNMIVDLDNVVKKVQAAQSEAKVVSQYHELVVQARDDFRKELDSITPDITPGWKGMSISDLAGKLSTDDLNSLIAHAHRRIDQLNRELAQQKATEKQHIELALEKHKLEEKRTFDSAVAKALEHHRSEIQAEQDRKVEEVRDAMENEMRTQLRRQAAAHTDHLRDVLKVQEQELKYEFEQGLSEKLSEQELEFRRRSQEQMDSFTLDINTAYARLRGIEQAVQSHAVAEEEARKAHQLWLSVEALKYSMKTSSAEMPTIPLGSAVEAIR--VNCSDNEFTQALTAAIPPESLTRGVYSEETLRARFYAVQKLARRVAMIDETRNSLYQYFLSYLQSLLLFPPKQL-KPPAELYPE--DINTFKLLSYASYCIEHGDLELAAKFVNQLKGESRRVAQDWLKEARMTLETKQIVEILTAYASAVGIGT 751
[Close]
BLAST of MICOS complex subunit MIC60 vs. Ensembl Mouse
Match: Immt (inner membrane protein, mitochondrial [Source:MGI Symbol;Acc:MGI:1923864])

HSP 1 Score: 201.83 bits (512), Expect = 3.121e-54
Identity = 147/509 (28.88%), Postives = 269/509 (52.85%), Query Frame = 2 
Query:  686 IQDHSQKLKRAIEDD---GTTIPNPWEEVNESNHLQQTAKTKSDKEMKRLELAIKQLELSINEGNHSEDLKSNPSIHTGQEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNVSNWTKKHT-----DKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREAL----LKEREKMRASIDGWRM-------RVEGIEAAVEGRADEEILSREAQDMWVACHAL-HGVLTGNGATPPLARYLNSFEEA--AQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECDTEIDPESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSSKTAGS 2146
            ++ HS  LK A+++    G      W  V  +   ++ A  ++   + + +  +++++  I +    E   + P I   +  L +    +   +  ++ AQ  A++ +QY EL+ Q ++ F++EL S+ P+++   K  +      KLS DDLN++I HAHRR+ QL   +A+ ++ E   ++ AL + + +++ + +  V   LE  RS+   E   ++++++   E E+R  L RQA+AH +H+  +LK+Q+ E+  +    + E L    L+ R + +  +D + +       R+ GIE AV+  A  E  +R+A  +W++  AL + + T +   P +   L S  EA     S     Q    +IP  +L +GV ++  L  RF  ++++ RRVAMIDET  SL  Y +S+L+SL+L  P  L +   E+ PE  +I+T ++++ A   I   D +LA + +N LKG  R +  DW+ +AR+ LETK   + L++Y S+   G+
Sbjct:  237 VKAHSNILKTAMDNSEIAGEKKSAQWRTVEGALKERRKAVDEAADALLKAKEELEKMKTIIEDAKKREIAGATPHITAAEGRLHNMIVDLDNVVKKVQAAQSEAKVVSQYHELVVQARDDFRKELDSITPDITPGWKGMSISDLAGKLSTDDLNSLIAHAHRRIDQLNRELAQQKATEKQHIELALEKHKLEEKRTFDSAVAKALEHHRSEIQAEQDRKVEEVRDAMENEMRTQLRRQAAAHTDHLRDVLKVQEQELKYEFEQGLSEKLSEQELEFRRRSQEQMDSFTLDINTAYARLRGIEQAVQSHAVAEEEARKAHQLWLSVEALKYSMKTSSAEMPTIP--LGSAVEAIRVNCSDNEFTQALTAAIPPESLTRGVYSEETLRARFYAVQKLARRVAMIDETRNSLYQYFLSYLQSLLLFPPKQL-KPPAELYPE--DINTFKLLSYASYCIEHGDLELAAKFVNQLKGESRRVAQDWLKEARMTLETKQIVEILTAYASAVGIGT 740
[Close]
BLAST of MICOS complex subunit MIC60 vs. Ensembl Mouse
Match: Immt (inner membrane protein, mitochondrial [Source:MGI Symbol;Acc:MGI:1923864])

HSP 1 Score: 117.087 bits (292), Expect = 1.856e-28
Identity = 76/219 (34.70%), Postives = 121/219 (55.25%), Query Frame = 2 
Query: 1499 IDGWRMRVEGIEAAVEGRADEEILSREAQDMWVACHAL-HGVLTGNGATPPLARYLNSFEEA--AQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECDTEIDPESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSSKTAGS 2146
            I+    R+ GIE AV+  A  E  +R+A  +W++  AL + + T +   P +   L S  EA     S     Q    +IP  +L +GV ++  L  RF  ++++ RRVAMIDET  SL  Y +S+L+SL+L  P  L +   E+ PE  +I+T ++++ A   I   D +LA + +N LKG  R +  DW+ +AR+ LETK   + L++Y S+   G+
Sbjct:   36 INTAYARLRGIEQAVQSHAVAEEEARKAHQLWLSVEALKYSMKTSSAEMPTIP--LGSAVEAIRVNCSDNEFTQALTAAIPPESLTRGVYSEETLRARFYAVQKLARRVAMIDETRNSLYQYFLSYLQSLLLFPPKQL-KPPAELYPE--DINTFKLLSYASYCIEHGDLELAAKFVNQLKGESRRVAQDWLKEARMTLETKQIVEILTAYASAVGIGT 249
[Close]
BLAST of MICOS complex subunit MIC60 vs. UniProt/SwissProt
Match: sp|Q22505|IMMT1_CAEEL (MICOS complex subunit MIC60-1 OS=Caenorhabditis elegans OX=6239 GN=immt-1 PE=2 SV=2)

HSP 1 Score: 210.305 bits (534), Expect = 8.403e-57
Identity = 156/523 (29.83%), Postives = 261/523 (49.90%), Query Frame = 2 
Query:  590 NEVFSNKLSNQIDSVEAASTSVILHLMEYADKIQDHSQKLKRAIEDDGTTIPNPWEEVNES-NHLQQTAKTKSDKEMKRLELAIKQLELSINEGNHSEDLKSNPSIHTGQEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNVSNWTKKHTDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREALLKEREKMRASIDGWRMRVEGIEAAVEGRADEEILSREAQDMWVACHAL-----HGVLTGNGATP---PLARYLNSFEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILL-TPSHLIECDTEIDPESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTS 2128
            N+    KL   I S E          ++  + I +H+  LK+ ++D        WE V  +    +  A+  S +E+      I  L   +N+G       +NP +   QE  +  ++++ +  A + K++  + + NQYK+LI + +++F  E+ S+ PNV    K     L+ D+LNA+I HAH ++ QL+ ++++ +  E + +  AL EQR  DE  A  K+ +E+ R   +  +E +  L + +   E EL   L R ASAH+EH+ Q+++ Q+   + + +  V EA+L+ER      +     R+EGIE A+  R   +  +R A+  W+ACH L     HG   GN       PL   LN  +E   P    V    ++S PK A   G  T+  L  RF+++ ++ R+ A IDE   +L  Y  S+++SL L+  P      D  ID   +  D  ++++ A+  +   D D AIR++ LLKG P  +  DWI D R YLE++L A  L ++ +
Sbjct:  160 NQQLEEKLKIAIHSAEGKVRLATEAKLKTINAINEHASILKQTVDDAKHA---NWENVTSALQRAEAEARVDSGQEVDGRNY-IDNLRKIVNDGKRDSTTATNPLLLNAQETANKLSHQLDEINALVNKSRQESAVLNQYKDLIEKSRQQFALEMKSILPNVDIHAKDKN--LNEDELNALIAHAHLKVDQLRCQLSDQQVREELHISKALEEQRLADERIASEKLSIEMSRVGRQNELEIERALVESRSSWEGELENQLKRTASAHSEHLEQVIRTQRQLFEIEQNQKVEEAVLQERNLHSKQVGAALSRLEGIEEALGSRVALDNENRRAKQFWIACHNLIDTLKHGNKAGNNIDERRLPLNESLNLLKE-VNPEDEFV-NAIIDSFPKQATTVGTYTEQDLKNRFEQLYKIGRKTASIDENGGTLGAYFWSYVKSLFLVDMPQQYGNLDA-ID--VNNTDNYEILSRAKQYVHNGDLDKAIRVVQLLKGQPAHLARDWIVDTRSYLESRLLAQLLVAHAA 671
[Close]
BLAST of MICOS complex subunit MIC60 vs. UniProt/SwissProt
Match: sp|Q16891|MIC60_HUMAN (MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1)

HSP 1 Score: 206.838 bits (525), Expect = 4.862e-55
Identity = 137/413 (33.17%), Postives = 230/413 (55.69%), Query Frame = 2 
Query:  965 IEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNV-SNW----TKKHTDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREAL----LKEREKMRASIDGWRM-------RVEGIEAAVEGRADEEILSREAQDMWVACHAL-HGVLTGNGATP--PLARYLNSFEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECDTEIDPESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSSKTAGS 2146
            ++ AQ  A++ +QY EL+ Q ++ FK+EL S+ P V   W         DKLS DDLN++I HAHRR+ QL   +AE ++ E   +  AL +Q+ +++ + +  V   LE  RS+   E   ++++++   E E+R  L RQA+AH +H+  +L++Q+ E+  +    + E L    L+ R   +  +D + +       R+ GIE AV+  A  E  +R+A  +W++  AL + + T +  TP  PL   + + +  A  S     Q    +IP  +L +GV ++  L  RF  ++++ RRVAMIDET  SL  Y +S+L+SL+L  P  L +   E+ PE  +I+T ++++ A   I   D +LA + +N LKG  R +  DW+ +AR+ LETK   + L++Y S+   G+
Sbjct:  345 VQAAQSEAKVVSQYHELVVQARDDFKRELDSITPEVLPGWKGMSVSDLADKLSTDDLNSLIAHAHRRIDQLNRELAEQKATEKQHITLALEKQKLEEKRAFDSAVAKALEHHRSEIQAEQDRKIEEVRDAMENEMRTQLRRQAAAHTDHLRDVLRVQEQELKSEFEQNLSEKLSEQELQFRRLSQEQVDNFTLDINTAYARLRGIEQAVQSHAVAEEEARKAHQLWLSVEALKYSMKTSSAETPTIPLGSAVEAIK--ANCSDNEFTQALTAAIPPESLTRGVYSEETLRARFYAVQKLARRVAMIDETRNSLYQYFLSYLQSLLLFPPQQL-KPPPELCPE--DINTFKLLSYASYCIEHGDLELAAKFVNQLKGESRRVAQDWLKEARMTLETKQIVEILTAYASAVGIGT 752
[Close]
BLAST of MICOS complex subunit MIC60 vs. UniProt/SwissProt
Match: sp|Q8CAQ8|MIC60_MOUSE (MICOS complex subunit Mic60 OS=Mus musculus OX=10090 GN=Immt PE=1 SV=1)

HSP 1 Score: 202.216 bits (513), Expect = 1.864e-53
Identity = 145/509 (28.49%), Postives = 268/509 (52.65%), Query Frame = 2 
Query:  686 IQDHSQKLKRAIEDD---GTTIPNPWEEVNESNHLQQTAKTKSDKEMKRLELAIKQLELSINEGNHSEDLKSNPSIHTGQEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNVSNWTKKHT-----DKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREAL----LKEREKMRASIDGWRM-------RVEGIEAAVEGRADEEILSREAQDMWVACHAL-HGVLTGNGATP--PLARYLNSFEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECDTEIDPESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSSKTAGS 2146
            ++ HS  LK A+++    G      W  V  +   ++ A  ++   + + +  +++++  I +    E   + P I   +  L +    +   +  ++ AQ  A++ +QY EL+ Q ++ F++EL S+ P+++   K  +      KLS DDLN++I HAHRR+ QL   +A+ ++ E   ++ AL + + +++ + +  V   LE  RS+   E   ++++++   E E+R  L RQA+AH +H+  +LK+Q+ E+  +    + E L    L+ R + +  +D + +       R+ GIE AV+  A  E  +R+A  +W++  AL + + T +   P  PL   + +       S     Q    +IP  +L +GV ++  L  RF  ++++ RRVAMIDET  SL  Y +S+L+SL+L  P  L +   E+ PE  +I+T ++++ A   I   D +LA + +N LKG  R +  DW+ +AR+ LETK   + L++Y S+   G+
Sbjct:  248 VKAHSNILKTAMDNSEIAGEKKSAQWRTVEGALKERRKAVDEAADALLKAKEELEKMKTIIEDAKKREIAGATPHITAAEGRLHNMIVDLDNVVKKVQAAQSEAKVVSQYHELVVQARDDFRKELDSITPDITPGWKGMSISDLAGKLSTDDLNSLIAHAHRRIDQLNRELAQQKATEKQHIELALEKHKLEEKRTFDSAVAKALEHHRSEIQAEQDRKVEEVRDAMENEMRTQLRRQAAAHTDHLRDVLKVQEQELKYEFEQGLSEKLSEQELEFRRRSQEQMDSFTLDINTAYARLRGIEQAVQSHAVAEEEARKAHQLWLSVEALKYSMKTSSAEMPTIPLGSAVEAIR--VNCSDNEFTQALTAAIPPESLTRGVYSEETLRARFYAVQKLARRVAMIDETRNSLYQYFLSYLQSLLLFPPKQL-KPPAELYPE--DINTFKLLSYASYCIEHGDLELAAKFVNQLKGESRRVAQDWLKEARMTLETKQIVEILTAYASAVGIGT 751
[Close]
BLAST of MICOS complex subunit MIC60 vs. UniProt/SwissProt
Match: sp|P91928|MIC60_DROME (MICOS complex subunit Mic60 OS=Drosophila melanogaster OX=7227 GN=Mitofilin PE=1 SV=4)

HSP 1 Score: 176.792 bits (447), Expect = 7.050e-45
Identity = 175/686 (25.51%), Postives = 327/686 (47.67%), Query Frame = 2 
Query:  188 QQSAFVPIFLGISSITLLGTGLSYY-YNDDFR---EKVAPYLPKRTKQFLDEYFDIP---ITDRIMKKWDSFNFFDKLSIKSNKMESFTSRFKGSKESNGPESSQKESKPFMNESVK------KVPRTPSEKIKDDVE-----KEAERLKKLNEVFSNKLSNQIDSVEAA-STSVILHLMEYADKI-------QDHSQKLKRAIEDDGTTIPNPWEEVNESNHLQQTAKTKSDKEMKRLELAIKQLELSINEGNHSEDLKSNPSIHTGQEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNVSNWTKKHTDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISA-EGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREALLKEREKMRASIDGWRMRVEGIEAAVEGRADEEILSREAQDMWVACHALHGVLTGNGATP---------PLARYLNSFEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECD-TEIDP-ESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSS 2131
            +++ F  + L +S +  +G  ++Y  Y+DDFR   EK  P      K  L E  + P   IT  +  + D       +   ++ ++S TS+  G       +   K+SK    E VK      K P  PSE  K + +       A       +   N L   +  +E A   S  L + EY   I        D  + + +A+E+   ++   W  +      + TA   +++  +  +  I   E++++    +++ K   ++    + L      +K +L    + +  A ++++Y   + + +  F  E+ S+ P +S   KK    LS +DL+  I+HA+  +   Q  +  L++   +RL  A+   R  ++  A   +++  LE ER K ++E Q+++  +    +  LR  L +QA AH +HI  ++  ++ ++ +     + + L  E+   +  + G   ++ G++AA+  RAD E  + +AQ +W AC AL   +    ATP         PL   +N+  + A+     ++   LES+PK A E+GV  ++ L +RF  ++RV RR+A++ E  A LP+Y +S+L+SL +L P + I  D  E  P +  ++DT  ++  A   + R DF  A++ +NLL+G  R I  +W+ +AR+ LET+ AA+ L ++ ++
Sbjct:   67 REAGFGKVVLFVSPLAAVGGVITYAKYDDDFRKLVEKNVPGAGSVIKVALQE--EPPFKGITKNVNDQIDKVK--SGIETVTSTVDSVTSKVTGLFGGGSGDDKSKKSKV---EPVKATPAEEKRPSKPSEVSKTEAKPVSKPAAAAAPAPAAKPKDNPLPRDVVELEKAIELSAQLAVKEYNVAIGVLKGFNDDVRKVVDKAVENGENSL---WTTLKNRASARDTAVATAERAAREAQEKIVACEIALSAAATAQNAKKVEAVRDKIKKLVDHIGNVKDELY---RHKDTASVSDKYWRNVEKARNYFIDEIESIFPGLSLADKKLN--LSKEDLDLFILHAYTHVLAYQKELQRLQTDGELRLKRAIDSVRGDNDSEALRAQLEYHLEAERRKLAVENQKKIFHIHAESDKLLRLQLKKQAEAHADHIKDIVAQRETDLTRSFKRELEDKLATEKANYKLQLAGMLGKLRGMDAALAERADAERTANQAQALWAACQALWASV--RAATPGVHYKDRLRPLKNEINAIAKVAKGDD--LVAAVLESVPKEAQERGVYPEDALRERFLNVERVARRLALVPEEGAGLPIYFLSYLQSLFILRPDNPISKDELENKPFDYSKLDTYDILNRARYHVDRSDFLQALKYMNLLQGASRKIAGEWMKEARLMLETQQAANTLMAHAAA 733
[Close]
BLAST of MICOS complex subunit MIC60 vs. UniProt/SwissProt
Match: sp|Q3KR86|MIC60_RAT (MICOS complex subunit Mic60 (Fragment) OS=Rattus norvegicus OX=10116 GN=Immt PE=1 SV=1)

HSP 1 Score: 144.436 bits (363), Expect = 1.129e-34
Identity = 141/573 (24.61%), Postives = 258/573 (45.03%), Query Frame = 2 
Query:  209 IFLGISSITLLGTGLSYYYNDDFREKVAPYLPKRTKQFLDEYFDIPITDRIMKKWDSFNFFDKLSIKSNKMESFTSRFKGSKESNGPESSQKESKPFMNESVKKVPRTPSEKIKDDVEKEAERLKKLNEVF-----SNKLSNQIDSVEAASTSVILHLMEYADKIQDHSQKLKRAIEDD---GTTIPNPWEEVNESNHLQQTAKTKSDKEMKRLELAIKQLELSINEGNHSEDLKSNPSIHTGQEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNVS-NWTKKH----TDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREAL----LKEREKMRASIDGWRM-------RVEGIEAAVEGRADEEILSREAQDMWVACHAL-HGVLTGNGATP--PLARYLNSFEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASL 1846
            +F+G     + GT L   ++  FRE V   +P   K F       P T  + KK        K+S  S  M         ++E+NG   +     P            P  + +D +  E     +    F     +  L + ++     +   I         ++ HS  LK A+++    G      W  V  +   ++ A  ++   + + +  +++++  I +    E   + P I   +E L S    +   +  ++ AQ  A++ +QY EL+ Q ++ F++EL S+ P+++  W           LS DDLNA+I HAHRR+ QL   +A+ ++ E   ++ AL  Q+ +++ + +  V   LE  RS+   E   ++++++   E E+R  L RQA+AH +H+  +LK+Q+ E+  +    + E L    L+   + +  +D + +       R+ GIE AV+  A  E  +R+A  +W++  AL + + T +   P  PL   + +   +   S     Q    +IP  +L +GV ++  L  RF  ++++  RVAMIDET  SL
Sbjct:   52 LFVGGG---IGGTILYAKWDSHFRESVEKTIPYSDKLFGMVLGSAPYTVPLPKKPIQSGPL-KISSVSEVMTDSELPMAQTQETNGDTPASAAGDP-----------APEVEHEDTINTECPNTDEGTSTFVTAALAKSLEDALNQTATVTRQTITAQNAAVQAVKAHSSTLKTAMDNSEIAGEKKSAQWRTVEGALKERRKAVDEAADALLKAKEELEKMKTIIEDAKKREIAGATPYITAAEEKLHSMIVDLDSVVKKVQAAQSEAKVVSQYHELVVQARDDFRKELDSITPDITPGWKGMSISDLAGTLSTDDLNALIAHAHRRIDQLNRELAQQKATEKQHIELALERQKLEEKRAFDSAVAKALEHHRSEIQAEQDRKVEEVRDAMENEMRTQLRRQAAAHTDHLRDVLKVQEQELKFEFEQDLSEKLSEQELEFHRRSQEQMDNFTLDINTAYARLRGIEQAVQSHAVAEEEARKAHQLWLSVEALKYSMKTSSAEMPTIPLGSAVEAIRVSC--SDNEFTQALTAAIPPESLTRGVYSEETLRARFYAVQKLAGRVAMIDETKNSL 607
[Close]
BLAST of MICOS complex subunit MIC60 vs. TrEMBL
Match: A0A2T7PBT7 (MICOS complex subunit MIC60 OS=Pomacea canaliculata OX=400727 GN=C0Q70_10153 PE=3 SV=1)

HSP 1 Score: 295.819 bits (756), Expect = 8.124e-85
Identity = 199/675 (29.48%), Postives = 366/675 (54.22%), Query Frame = 2 
Query:  212 FLGISSITLLGTGLSYYYNDDFR---EKVAPYLPKRTKQFLDEYFD-IPITDRIMKKWDSFNFFDKLSIKSNKMESFTSRFKGSKESNGP------ESSQKESKPFMNESVKKVPRTPSEKIKDDVEKEAE-RLKKLNEVFSNK-------LSNQIDSVEAASTSVILHLMEYADKIQDHSQKLKRAIEDDGTTIP--NPWEEVNESNHLQQTAKTKSDKEMKRLELAIKQLELSINEGNHSEDLKSNPSIHTGQEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNVSNWTKKHTDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREALLKEREKMRASIDGWRMRVEGIEAAVEGRADEEILSREAQDMWVACHALHGVLT-GN-------GATPPLARYLNSFEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECDTEID-PESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSSKTAGSI 2149
             LG++++ + G     +Y+ +FR   EK  PY    +K+FLD  F+ +P         +  ++F     + +         +  KE   P      E  +K+ K    E  K+ P+  +E+ K++  +  E R ++     + +       L N I        + I    +  D ++ H+  LK+A+ED    +   + W++V E+   ++    ++DK +K     + +L  +I++G  ++    N  ++T QE  +  N  +K    ++ + +  A++ ++YK+LI +G+++F +EL S+ P+V     + + KL+ ++LNA+I HAHRR+ QLQ  +AE  +ME  R+  AL +Q+K++++     V +E ER +   ++E Q      +   E ELR+ L RQA+AH++H+  +L +Q+ E++ Q    +   +L+ER+  +  + GW  R++GIEAAVE RA+ E ++R AQD+W++C AL+GV+  GN           PL + + +  +A      P ++  +++IP+ AL++GV T++ L +RF ++K+VC+RVAMID+   SL  +++S+++SL +      +   TE D    +E+D    +A AE  + R D + A+R +N LKG PR +  DWI +A++ LE + AA AL+++ S+   G+I
Sbjct:   79 LLGVTTVGIGGVIGYAWYDPEFRKYLEKKVPY----SKKFLDVVFEYLP---------NRSSYFPSTPEEPSPPPCPPPLSRPKKEDTRPLNLGPKEPEKKDDKCAQIEVPKEDPKITAERAKEEQRRLVEQRFREKEAEEAAENAALEVVLDNLIRKANEVVETTICIQKKQIDAVRKHTALLKQAMEDVSEILDKDHQWQQVAEAFKQRENISKEADKSVKEARETLDRLRSAIDDGKKNKVTHRNKVLNTAQETFTKVNNELKNAEKEVSRCECEARVLSKYKDLIERGRKQFAEELDSIMPDVK--LGRRSKKLTEEELNALIAHAHRRIEQLQRTLAEQVAMEAKRIQDALEQQKKEEDLLTTKLVMIENERLKDTFAMEKQNWEANARVEFEKELRQQLARQAAAHSDHLKDVLCVQEQELNAQCEKRIHAKILEERQSFQTEVVGWIGRLKGIEAAVEARAESEKIARVAQDLWLSCIALNGVIRHGNEEAHEWENRLRPLKKEVEAVSDAG--GKHPFVETIIQTIPEEALDRGVWTEDSLRERFPRVKKVCKRVAMIDDKGGSLFKFMLSYVQSLFVFDS---VFAKTEEDLVNVNELDAFSALAHAEFWLERGDLETALRFMNQLKGEPRRVASDWIREAKLLLEARQAAYALTAFASASGLGTI 733
[Close]
BLAST of MICOS complex subunit MIC60 vs. TrEMBL
Match: V3ZVC8 (MICOS complex subunit MIC60 (Fragment) OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_128909 PE=3 SV=1)

HSP 1 Score: 281.952 bits (720), Expect = 7.739e-82
Identity = 172/524 (32.82%), Postives = 302/524 (57.63%), Query Frame = 2 
Query:  611 LSNQIDSVEAASTSVILHLMEYADKIQDHSQKLKRAIEDDGTTIPNP---WEEVNESNHLQQTAKTKSDKEMKRLELAIKQLELSINEGNHSEDLKSNPSIHTGQEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNVSNWTKKHTDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREALLKEREKMRASIDGWRMRVEGIEAAVEGRADEEILSREAQDMWVACHALHGV--------LTGNGATPPLARYLNSFEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECDTEIDPESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSSKTAGSI 2149
            + N +D+    + +VI    +  D  + H++ LK+A+ +D + I N    WEEV +   L++ A  ++ K        + +L+ ++ EG      K N  + T QE  +   + I    A +EKA   +++ ++YK+L+ +G+++F++EL S+ P+V    K    KL+ D+LN+MI HAHRR+ QLQ ++AE  ++E  +++ AL  QR +DE   + +V +E +R R +  +E +   D  K   E ELR  L RQA+AH++H+  +L+ Q+ ++ +     +   L++ER+  +  + GW  R++GIEAAV+ RA+ E  +R AQ++W+AC A++G+        +T      PLA    +  EAA   + P +Q  L+++P+ AL +GV T++ L +RF K+K+VC+RVAMIDE   +L  Y +S+++S  +    +    D  +D    ++DT  ++A  +  + + D   A+R +N L+G PR +  DWI +A++ LET+ AA AL+S+ S+   G+I
Sbjct:    8 VENLVDTNSKLTKAVIEAQNKVIDLTKKHTEALKKAM-NDTSQILNKDKQWEEVADIYSLREEAVKEAQKLKDSAIDNLTKLQKAVEEGKQDPVTKKNQILKTSQEKWNKLTHEIDDITAQVEKAASESRVVSKYKDLVEKGRKQFQKELESIMPDVKLGEKGK--KLTEDELNSMIAHAHRRIEQLQKQLAEQLAVESQKIEKALEFQRNEDEKLIQNRVNVERQRLREQFKLEKERWNDDSKVEFEQELRHHLARQAAAHSDHLKDVLRNQEADLSQYFEREMHTRLIEERQSFQTEVAGWIARLQGIEAAVDARAENERTARTAQELWLACIAMNGIIRLGKEDGITMEDKLQPLASQATAITEAA--GNHPFIQAVLKTVPEEALTRGVYTEDSLKQRFPKVKKVCKRVAMIDENGGTLFRYFLSYVQSFFIFNSVYATSIDDTVDI--SDLDTFTILAHTDYYLEKGDLLQALRFMNQLQGEPRKVAADWIKEAKLLLETQQAAFALTSFASASGLGTI 524
[Close]
BLAST of MICOS complex subunit MIC60 vs. TrEMBL
Match: K1QNN9 (MICOS complex subunit MIC60 OS=Crassostrea gigas OX=29159 GN=CGI_10028115 PE=3 SV=1)

HSP 1 Score: 268.47 bits (685), Expect = 3.198e-75
Identity = 162/505 (32.08%), Postives = 297/505 (58.81%), Query Frame = 2 
Query:  671 EYADKIQDHSQKLKRAIEDDGTTIPNP---WEEVNESNHLQQTAKTKSDKEMKRLELAIKQLELSINEGNHSEDLKSNPSIHTGQEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNVSNWTKKHTDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREALLKEREKMRASIDGWRMRVEGIEAAVEGRADEEILSREAQDMWVACHALHGV--------LTGNGATPPLARYLNSFEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIE-CDTEIDPESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSSKTAGSI 2149
            E    ++ H+Q L+ A+ DD T I N    W  V E+   +      + K M  L L  ++L+  + E  +++  KSN  ++  QE  ++ + ++    + I K++   +   ++ +L+ +G+++F++EL SL P+V     K   KLS ++LN++I HAHRR+ QLQ ++A   ++E  R+  AL  QRK DE   + +++ E ++ ++   +E Q+  ++ +   EVELR+ L RQA+AH++H+ ++LK+Q+ E+ +++        ++ER+  +A I GW  R++GIE AVE RA  E ++REAQD+W+AC AL+G         L       PL   + +  +AA   + P + + + +IP+ A  +GV T++ L +RF+K+  VC++VA IDE   +L  Y +S+L+S+ +   S+ ++  + ++D ES  +D  +++A+A   + R DF+ A+R +N L+G  R +  DW+ +A++ LET+ AA AL+++ S+   G++
Sbjct:  193 EVISAVKKHAQALQTAM-DDKTDILNKEGQWNAVTEAFQKRGVVTDNAKKVMDSLRLEKEKLKAMVEEARNNKSTKSNKILNQAQEAYNTVSSKLNAIESAIAKSESENRGLVKFNDLVEEGKKKFQKELESLMPDVKPGKGK---KLSEEELNSLIAHAHRRIEQLQHQLANHLALEKERIQEALDMQRKADESVCDRRIEDEAQKIKNNVDLEKQKWGEEARVQFEVELRQQLARQAAAHSDHLQEVLKVQEQELLQKYERQFNLKFIEERQAFQAEIAGWVARLKGIETAVENRAAAEKIAREAQDLWLACLALNGTIRRGKEEELAWEERLKPLGNEIVAVYDAA--GNHPFVNMIVSTIPEKAYVRGVWTEDTLRERFEKVSSVCKKVAAIDECGGTLYKYFISYLQSVFISLRSYDVKNLNDQVDVES--MDNFEILANASYWMDRGDFEAAVRYMNQLQGEARKVAGDWLKEAKLLLETRQAAFALTAFASASGLGTV 689
[Close]
BLAST of MICOS complex subunit MIC60 vs. TrEMBL
Match: A0A3S1B2R0 (MICOS complex subunit MIC60 OS=Elysia chlorotica OX=188477 GN=EGW08_013772 PE=3 SV=1)

HSP 1 Score: 263.848 bits (673), Expect = 8.444e-73
Identity = 170/515 (33.01%), Postives = 291/515 (56.50%), Query Frame = 2 
Query:  635 EAASTSVILHLMEYADKIQDHSQKLKRAIEDDGTTIPNP--WEEVNESNHLQQTAKTKSDKEMKRLELAIKQLELSINEGNHSEDLKSNPSIHTGQEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNVSNWTKKHTDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKD-------EISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREALLKEREKMRASIDGWRMRVEGIEAAVEGRADEEILSREAQDMWVACHALHGVL-TGNGA----TPPLARYLNSFEEAAQPSS--RPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECDTEIDPESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSS 2131
            E+ S   +   ++YA  +++H++ L++A++D    +     WE V  +   ++ AK +++  +   +  I++L   I  G  S+  K NP+I    + ++     I    A I +A+  A +  +YK+L+ +G+++F++E+ SL P+V   T K   KLS D+LNA+I HAHRR+ QLQ ++AE  +ME  RL  AL  QR++D        +    +++ E + E+ K  +E+  +L       E E+R+ L RQA+AH++HI  +L +Q+D++ ++ +  +   LL+EREK +  + GW  R++GIEAAV+ RAD E L+R AQD+W+AC AL+ +L  GN +      P+   L S  EA   S    P ++   ++IP  AL++GV T++ L  RF ++ R+CRR+ ++   + SL  Y+VS+  S ++    H      E+D    ++D   +IA A+  + R   +LA++ +  L G  R     WITDAR+ LETK  A  L+++ S+
Sbjct:  259 ESLSEEAVKAQVDYASAVRNHTKLLRQAMDDTSDILQKDAQWEAVAIAYSEREYAKDRANDLVAEAKRTIEKLREVIGNGKSSKATKQNPAIVPASKKINEFLKDIGGSAAQIRQAESEANVMLKYKDLVDKGKKQFQKEIESLLPDVKIGTGK---KLSEDELNALIAHAHRRIEQLQKQVAEHLAMERQRLKTALETQRQEDVHLTNSAVLDERARLKQEFDVEQQKMEMEYLVQL-------EAEVRKQLARQAAAHSDHIKDVLAVQQDQLAQEFNRELNAKLLEEREKFQTEVAGWISRLKGIEAAVDARADSEKLARSAQDLWLACIALNAILHFGNESETDEKKPVP--LRSKVEAIMNSGLKHPFVETVAKAIPAEALDEGVNTEDELKARFVRVARICRRLGLVQAPNTSLYKYLVSYFHSFLVFDHIHAQGAADELDLA--KLDNFDLIAYAQYWMDRGSLELALKFMTQLSGESRRAASGWITDARLLLETKQCAFTLTAFASA 759
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BLAST of MICOS complex subunit MIC60 vs. TrEMBL
Match: W4XLS8 (Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1)

HSP 1 Score: 260.381 bits (664), Expect = 2.606e-72
Identity = 179/523 (34.23%), Postives = 299/523 (57.17%), Query Frame = 2 
Query:  626 DSVEAASTSVILHLMEYADKIQDHSQKLKRAI----EDDGTTIPNPWEEVNESNHLQQTAKTKSDKEMKRLELAIKQLELSINEGNHSEDLKSNPSIHTG-QEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNVSNWTKKHTDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREALLK--EREKMRASIDGWRMRVEGIEAAVEGRADEEILSREAQDMWVACHAL-HGVLTGNGATP-------PLARYLNSFEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECDTEIDPESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSSKTAGSI 2149
            DSVEA   + +    E  +  + H+ KLK A+    E++G      W+EV  +   +  A T++ K       A+ +L+  + E N ++      S   G Q  L+   Y ++   A++  AQ  A+I   Y ELI +G+E FK+E+ SL P       K   KL+ ++LNA+I HAHRR++QLQ  +AE ++ME  RL AA+  Q+++DE   + KV +ELER+ +  ++ +Q + + +    E ELR  L RQA+AH++H++ +L+ Q+ E D+Q  L+V++ L++  ER+     + G   ++ G+EAAVEGRA  E+ +++AQ++W+AC  L   + TG            PLA  + + +EA+   S   +   +++IP+ AL +GV T++ L +R+D+ +RVC+RVAMIDETS+ +  Y +S+ +SL+LL        +  ID  +  +DT ++++ A   +   + + A+R  N L GMPR +  DW+ +AR+ LET  AA  LSS+ S+   G +
Sbjct:  160 DSVEATRIA-MGSKKEAVEATKQHTDKLKLAMGDLEEENGELKKKQWDEVVVAAENKLKAVTQASKGEAAAREALAKLKAVLEEANRTKTSAGQSSNLIGAQANLNQMVYDLEFATAEVVVAQNEARILKNYHELIQEGRESFKKEVQSLMPEAK--IGKKGKKLTEEELNALIAHAHRRVYQLQKGLAEQQAMEQKRLAAAMEVQKEEDEGVTKSKVMVELERQAADLAVLYQRKQEDLLAEAEQELRLQLRRQAAAHSDHLSDVLQQQRQEFDRQ--LSVQDVLVRDQERDNYYKQLSGAMAKLRGVEAAVEGRAGLEVQNQKAQELWLACETLKRTIATGKLEASSWEEKLKPLASEVQAIKEAS--VSNDFVDTVVKTIPEEALTRGVFTEDSLRQRWDQTQRVCKRVAMIDETSSGMFAYFLSYFQSLLLLNDPLPPNSEEAIDLST--LDTFKLVSYASYHMENGNLEQALRYANQLTGMPRKVASDWLREARLLLETSQAASVLSSHASASGLGGL 673
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BLAST of MICOS complex subunit MIC60 vs. Ensembl Cavefish
Match: immt (inner membrane mitochondrial protein [Source:NCBI gene;Acc:103027233])

HSP 1 Score: 219.55 bits (558), Expect = 2.070e-60
Identity = 157/537 (29.24%), Postives = 291/537 (54.19%), Query Frame = 2 
Query:  599 FSNKLSNQ-IDSVEAASTSVILHLMEYADKIQDHSQKLKRAI--EDDGTTIPNPWEEVNESNHLQQTAKTKSDKEMKRLELAIKQLELSINEGNHSEDLKSNPSIHTGQEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNV-SNWTKKHTDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREALLKEREKMR----ASIDGWRM-------RVEGIEAAVEGRADEEILSREAQDMWVACHALHGVL---TGNGATPPLARYLNSFEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECDTEIDP---ESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSSKTAGS 2146
            FS KL+ Q I + EAA T+           I  H+ +L+ A+  ED        W E+ ++   +  A  ++ + + + +  +++L + IN    S+   + P I   +E L S    + + +  ++ AQ  A+I +QY EL+++ + +F++ELSS+ P V +NW K  T KLS DDLN++I HAHRR+ QL   +AE    E IR++AAL +Q+ + + + +  V   ++    +  +E ++++ ++++  E E+R  L RQA+AH +H+  +LK+Q+ E+ ++   A+   ++++  + R      +D + +       R++G+E A++     E  +R+A  +W++  AL+  L     +  T PL   + + +E+   +     Q    ++P  +L +GV ++  L  RF  ++R+ RRVA+IDET  SL  Y +S+L+S++L       E + E  P    + ++DT +++A A  +I R D +LA + +N L G  R +  DW+ +AR+ LETK     LS+Y ++   G+
Sbjct:  249 FSAKLTLQAIGAQEAALTA-----------IGTHTHRLREAMDSEDPPDKKSAQWRELEDALSERTRAVDQAGQSLLQAKEQLEKLRVVINGAKESKIEAARPQILAAEENLHSMIVDLDKVVTKVQAAQTEAKIVSQYSELVNEAKVQFQKELSSITPEVQANW-KGLTGKLSADDLNSLIAHAHRRIDQLNRELAEQRVREQIRIEAALEQQKHEHQRAVDSAVDKAIQHNHEQLRLEQEKKMQEVREVMEAEMRTQLRRQAAAHTDHLRDVLKVQEQELREEAQEALSSKMMEQETQHRRLAQEQLDSFTLDMNSAYARLKGMEEAIDSHVVAEEEARKAHQLWLSVEALNYTLKTAAADAPTEPLEGAVRTIKESC--AENEFAQALATALPDESLTRGVYSEASLRARFYGVRRLARRVALIDETRNSLYQYFLSYLQSILLF------EKEQEAPPTKLAAQDLDTFKLLAYATYSIERGDLELAAKFVNQLHGESRRVAQDWLKEARLTLETKQVVSLLSAYANAVGLGT 765
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BLAST of MICOS complex subunit MIC60 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004532.1 (pep scaffold:Pmarinus_7.0:GL477554:141141:147823:1 gene:ENSPMAG00000004090.1 transcript:ENSPMAT00000004532.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 181.8 bits (460), Expect = 2.530e-49
Identity = 122/417 (29.26%), Postives = 219/417 (52.52%), Query Frame = 2 
Query:  965 IEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNVSNWTKKH-----TDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQH-----------SLAVREALLKEREKMRASIDGWRMRVEGIEAAVEGRADEEILSREAQDMWVACHALHGVLT------GNGATPPLARYLNSFEEAAQPSSRPVL------QLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECDTEIDPESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSS 2131
            +E AQ  A++ +QY+E+  + +E F+QEL S+ P    W  +         L+ ++LNA+++HAHRR  QL+  +AE +++E  RL  A  +QR  D+   E  +   L ++R +  +  Q +++++K   E+E+R  L R  +AH++H+ + LK+Q  E+   H            L  R  +L +R+     I+    +V GI  AV+G A+ E ++++A  +W+A  AL   L        +G   PLA++++        ++R VL      Q+   ++P  + E+GV +   L  RF  ++R+ RRVA+IDET  SL  Y +S++++ I   P+  ++   E     +  D  +V+A A   +   D + A R +  L+G  R +   W+ +AR+ LET+ A   L+++ S+
Sbjct:  127 VEAAQTEARLVSQYQEMAERAKEEFRQELESIVPG---WQGRGDALGLPGDLNKEELNALLLHAHRRTEQLRRELAERQALEEHRLVLAREQQRTVDQRGLEEALATALHQQRQELVVAQQRKIEELKDAMEMEMRTQLRRATAAHSDHLQEALKLQAFELGNSHKKELTDKMVEQDLMFRREILDQRDSFTQDINKAFAQVHGIRNAVDGLAEREEIAKKAHSLWLAGEALRTALAEAGPDGPDGPCVPLAKHVD--------AARAVLAESEFAQVVTGAVPSESRERGVYSLEALRHRFRSVRRLARRVALIDETRNSLYQYFLSYVQTFIAKFPTLTLKPPAEGVAVEELGDAFRVLAYAAFCLEHGDLEQAARFVTALRGEARRVADSWLHEARLTLETRQAIALLTAHASA 532
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BLAST of MICOS complex subunit MIC60 vs. Ensembl Nematostella
Match: EDO31080 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SYX7])

HSP 1 Score: 187.193 bits (474), Expect = 4.073e-51
Identity = 135/512 (26.37%), Postives = 270/512 (52.73%), Query Frame = 2 
Query:  644 STSVILHLMEYADKIQDHSQKLKRAIEDD--------GTTIPNPWEEVNESNHLQQTAKTKSDKEMKRLELAIKQLELSINEGNHSEDLKSNPSIHTGQEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNVSNWTKKHTDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREALLKEREKMRASIDGWRMRVEGIEAAVEGRADEEILSREAQDMWVACHALHGVLT-GNGATPPLARYLNSFEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECDTEIDPE---SDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSSKTAG 2143
            +T  +LH          H+ +LK A+ED           TI +  +E  ++    Q A+ K ++E+++  + IK+ E +   G     ++++       E  +  +Y +    A+++KA+    +  +Y++   + +   ++EL  + P  +   K+   K        ++ +A +R+  L+  +A+    E  RL   L+ QR++D   A+ +++ E ++  ++  +  +++  +M    E ++R+ L RQA+A+++H+ ++L++Q  E+ ++H   + +   +E +   A +     R+ G+E+A++GRA+ E  ++ +Q++W+AC AL   +  G     PL   +++  + + P   PV+   LE+IP  AL++GV  ++ LT RF++++R CRRVAM+ E SA    +++S+L+S  +       + D   D E   ++E+DT  ++A A+  I R D +L  RL+N L G  R + +DW+ + RI LET+ A   LSSY ++   G
Sbjct:   53 ATEAVLH----------HTDQLKHALEDVEVVSMKDLSKTILSSQKEAEDAITGAQEAQVKVNEEVEKFHILIKEAETA---GAKEAGVRAS-------EEAAKVSYGVLNATAELQKAKAQDMVLGEYQKFFDESRAVLRKELEEVMPGAAMSDKEQKAKGGK---TVLLAYARKRLEHLKQELAKHRQEEQKRLQQILSVQREEDNKLADIRLKQEKDKMMAEMDVALRKKESEMAAVFESDVRQQLRRQAAAYSDHLAEVLRVQAAELQERHREELEKKSNEEHQAFNAKLTAAFSRLRGVESAIDGRAEIEKTNKRSQELWLACQALTSAIDRGYQKRRPLNHEVSAVYDCS-PED-PVVNTVLEAIPPEALQKGVYNEDNLTARFNQVRRQCRRVAMVGEDSAGPWTFLLSYLQSFFIFD-----KFDPRTDGELVDAEELDTFGLLARADYYIKRGDLELGARLVNQLTGEARKLAYDWLKETRILLETRQAVRLLSSYAAAAAMG 534
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BLAST of MICOS complex subunit MIC60 vs. Ensembl Medaka
Match: immt (inner membrane mitochondrial protein [Source:NCBI gene;Acc:101155755])

HSP 1 Score: 213.386 bits (542), Expect = 3.157e-58
Identity = 150/510 (29.41%), Postives = 278/510 (54.51%), Query Frame = 2 
Query:  686 IQDHSQKLKRAIEDDGTTIPNP--WEEVNESNHLQQTAKTKSDKEMKRLELAIKQLELSINEGNHSEDLKS---NPSIHTGQEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNV-SNWTKKHTDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREALLKE----REKMRASIDGWRM-------RVEGIEAAVEGRADEEILSREAQDMWVACHALHGVLTGNGATPPLARYLNSFEEAAQPSSRP--VLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECDTEIDP----ESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSSKTAGS 2146
            I  H+QKLK A+E +         W+++  +   + +A T +   +++ + A+  L  +IN    S+DLK     P +   +E L      + + +A ++ A+  ++I +QY +L+ + +++F++E+SSL P + +NW K  T KLS DDLNA+I HAHRR+ QL   +AE    E + +DAAL +Q+ +D+   E  V   L+  + +  +E + +++++++  E E+R  L RQA+AH +H+  +LK+Q+ E+  +    +   LL++    R+  +  +D + +       R++G+E A++     E  +R A  +W++  AL+  L   G   P +  L+S  +  + S R         E++P  +L +GV  +  L  RF+ ++ +  RVA+IDE+  SL  Y +S+L++ +L         D +  P     S+++DT ++++ A   +   D +LA +L+N LKG  R +V DW+T+AR+ LET+     LS+Y ++   G+
Sbjct:  263 INQHTQKLKEAMEAESPPEEKSVQWKDLEAALMDRTSAVTDATAALQKAKEALDGLRATIN---GSKDLKVAAVRPLVLAAEENLHKMVVDLDRVVAQVQSAEVESKIVSQYSDLVQEAKQQFQKEVSSLTPEIQANW-KGLTGKLSTDDLNALIAHAHRRIDQLNRELAEQRVREQVHIDAALQQQKLEDQRVLERAVSSSLQHVKEEARLEQERKMNEVREVMEAEMRTQLRRQAAAHTDHVRDVLKVQEQELRAEAEQILSSKLLEQDTLHRQLTQEQLDSFTLDMNAAYARLKGVEEAIDSHLVAEDEARRAHQLWLSVEALNHTLKTAGTEEP-SVPLDSAAQMVRDSCRQDDFASALAEALPAESLSRGVYGEASLRARFNSLRSLVLRVALIDESHNSLYQYFLSYLQAALLFE-------DQQAAPPTQLSSEDLDTFKLLSYASYCLEHGDLELAAKLVNQLKGESRRVVEDWLTEARLTLETRQVVSLLSAYANAVGLGT 760
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BLAST of MICOS complex subunit MIC60 vs. Planmine SMEST
Match: SMESG000066687.1 (SMESG000066687.1)

HSP 1 Score: 1428.69 bits (3697), Expect = 0.000e+0
Identity = 694/697 (99.57%), Postives = 695/697 (99.71%), Query Frame = 2 
Query:   65 MLRINPRNKLVTLEYVIKRFNSKSTNLQSTSEKSHKQ--KYEYQQSAFVPIFLGISSITLLGTGLSYYYNDDFREKVAPYLPKRTKQFLDEYFDIPITDRIMKKWDSFNFFDKLSIKSNKMESFTSRFKGSKESNGPESSQKESKPFMNESVKKVPRTPSEKIKDDVEKEAERLKKLNEVFSNKLSNQIDSVEAASTSVILHLMEYADKIQDHSQKLKRAIEDDGTTIPNPWEEVNESNHLQQTAKTKSDKEMKRLELAIKQLELSINEGNHSEDLKSNPSIHTGQEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNVSNWTKKHTDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREALLKEREKMRASIDGWRMRVEGIEAAVEGRADEEILSREAQDMWVACHALHGVLTGNGATPPLARYLNSFEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECDTEIDPESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSSKTAGSI 2149
            MLRINPRNKLVTLEYVIKRFNSKSTNLQSTSEKSHKQ  +YEYQQSAFVPIFLGISSITLLGTGLSYYYNDDFREKVAPYLPKRTKQFLDEYFDIPITDRIMKKWDSFNFFDKLSIKSNKMESFTSRFKGSKESNGPESSQKESKPFMNESVKKVPRTPSEKIKDDVEKEAERLKKLNEVFSNKLSNQIDSVEAASTSVILHLMEYADKIQDHSQKLKRAIEDDGTTIPNPWEEVNESNHLQQTAKTKSDKEMKRLELAIKQLELSINEGNHSEDLKSNPSIHTGQEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNVSNWTKKHTDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREALLKEREKMRASIDGWRMRVEGIEAAVEGRADEEILSREAQDMWVACHALHGVLTGNGATPPLARYLNSFEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECDTEIDPESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSSKTAGSI
Sbjct:    1 MLRINPRNKLVTLEYVIKRFNSKSTNLQSTSEKSHKQNNRYEYQQSAFVPIFLGISSITLLGTGLSYYYNDDFREKVAPYLPKRTKQFLDEYFDIPITDRIMKKWDSFNFFDKLSIKSNKMESFTSRFKGSKESNGPESSQKESKPFMNESVKKVPRTPSEKIKDDVEKEAERLKKLNEVFSNKLSNQIDSVEAASTSVILHLMEYADKIQDHSQKLKRAIEDDGTTIPNPWEEVNESNHLQQTAKTKSDKEMKRLELAIKQLELSINEGNHSEDLKSNPSIHTGQEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNVSNWTKKHTDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREALLKEREKMRASIDGWRMRVEGIEAAVEGRADEEILSREAQDMWVACHALHGVLTGNGATPPLARYLNSFEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECDTEIDPESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSSKTAGSI 697
[Close]
BLAST of MICOS complex subunit MIC60 vs. Planmine SMEST
Match: SMESG000066687.1 (SMESG000066687.1)

HSP 1 Score: 1408.66 bits (3645), Expect = 0.000e+0
Identity = 685/695 (98.56%), Postives = 685/695 (98.56%), Query Frame = 2 
Query:   65 MLRINPRNKLVTLEYVIKRFNSKSTNLQSTSEKSHKQKYEYQQSAFVPIFLGISSITLLGTGLSYYYNDDFREKVAPYLPKRTKQFLDEYFDIPITDRIMKKWDSFNFFDKLSIKSNKMESFTSRFKGSKESNGPESSQKESKPFMNESVKKVPRTPSEKIKDDVEKEAERLKKLNEVFSNKLSNQIDSVEAASTSVILHLMEYADKIQDHSQKLKRAIEDDGTTIPNPWEEVNESNHLQQTAKTKSDKEMKRLELAIKQLELSINEGNHSEDLKSNPSIHTGQEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNVSNWTKKHTDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREALLKEREKMRASIDGWRMRVEGIEAAVEGRADEEILSREAQDMWVACHALHGVLTGNGATPPLARYLNSFEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECDTEIDPESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSSKTAGSI 2149
            MLRINPRNKLVTLEYVIKRFNSKSTNLQSTSEKSHKQKYEYQQSAFVPIFLGISSITLLGTGLSYYYNDDFREKVAPYLPKRTKQFLDEYFDIPITDRIMKKWDSFNFF          ESFTSRFKGSKESNGPESSQKESKPFMNESVKKVPRTPSEKIKDDVEKEAERLKKLNEVFSNKLSNQIDSVEAASTSVILHLMEYADKIQDHSQKLKRAIEDDGTTIPNPWEEVNESNHLQQTAKTKSDKEMKRLELAIKQLELSINEGNHSEDLKSNPSIHTGQEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNVSNWTKKHTDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREALLKEREKMRASIDGWRMRVEGIEAAVEGRADEEILSREAQDMWVACHALHGVLTGNGATPPLARYLNSFEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECDTEIDPESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSSKTAGSI
Sbjct:    1 MLRINPRNKLVTLEYVIKRFNSKSTNLQSTSEKSHKQKYEYQQSAFVPIFLGISSITLLGTGLSYYYNDDFREKVAPYLPKRTKQFLDEYFDIPITDRIMKKWDSFNFF----------ESFTSRFKGSKESNGPESSQKESKPFMNESVKKVPRTPSEKIKDDVEKEAERLKKLNEVFSNKLSNQIDSVEAASTSVILHLMEYADKIQDHSQKLKRAIEDDGTTIPNPWEEVNESNHLQQTAKTKSDKEMKRLELAIKQLELSINEGNHSEDLKSNPSIHTGQEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNVSNWTKKHTDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREALLKEREKMRASIDGWRMRVEGIEAAVEGRADEEILSREAQDMWVACHALHGVLTGNGATPPLARYLNSFEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECDTEIDPESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSSKTAGSI 685
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BLAST of MICOS complex subunit MIC60 vs. Planmine SMEST
Match: SMESG000066687.1 (SMESG000066687.1)

HSP 1 Score: 1401.34 bits (3626), Expect = 0.000e+0
Identity = 684/697 (98.13%), Postives = 685/697 (98.28%), Query Frame = 2 
Query:   65 MLRINPRNKLVTLEYVIKRFNSKSTNLQSTSEKSHKQ--KYEYQQSAFVPIFLGISSITLLGTGLSYYYNDDFREKVAPYLPKRTKQFLDEYFDIPITDRIMKKWDSFNFFDKLSIKSNKMESFTSRFKGSKESNGPESSQKESKPFMNESVKKVPRTPSEKIKDDVEKEAERLKKLNEVFSNKLSNQIDSVEAASTSVILHLMEYADKIQDHSQKLKRAIEDDGTTIPNPWEEVNESNHLQQTAKTKSDKEMKRLELAIKQLELSINEGNHSEDLKSNPSIHTGQEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNVSNWTKKHTDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREALLKEREKMRASIDGWRMRVEGIEAAVEGRADEEILSREAQDMWVACHALHGVLTGNGATPPLARYLNSFEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECDTEIDPESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSSKTAGSI 2149
            MLRINPRNKLVTLEYVIKRFNSKSTNLQSTSEKSHKQ  +YEYQQSAFVPIFLGISSITLLGTGLSYYYNDDFREKVAPYLPKRTKQFLDEYFDIPITDRIMKKWDSFNFF          ESFTSRFKGSKESNGPESSQKESKPFMNESVKKVPRTPSEKIKDDVEKEAERLKKLNEVFSNKLSNQIDSVEAASTSVILHLMEYADKIQDHSQKLKRAIEDDGTTIPNPWEEVNESNHLQQTAKTKSDKEMKRLELAIKQLELSINEGNHSEDLKSNPSIHTGQEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNVSNWTKKHTDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREALLKEREKMRASIDGWRMRVEGIEAAVEGRADEEILSREAQDMWVACHALHGVLTGNGATPPLARYLNSFEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECDTEIDPESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSSKTAGSI
Sbjct:    1 MLRINPRNKLVTLEYVIKRFNSKSTNLQSTSEKSHKQNNRYEYQQSAFVPIFLGISSITLLGTGLSYYYNDDFREKVAPYLPKRTKQFLDEYFDIPITDRIMKKWDSFNFF----------ESFTSRFKGSKESNGPESSQKESKPFMNESVKKVPRTPSEKIKDDVEKEAERLKKLNEVFSNKLSNQIDSVEAASTSVILHLMEYADKIQDHSQKLKRAIEDDGTTIPNPWEEVNESNHLQQTAKTKSDKEMKRLELAIKQLELSINEGNHSEDLKSNPSIHTGQEVLSSTNYRIKQKLADIEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNVSNWTKKHTDKLSNDDLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKVQMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLKIQKDEIDKQHSLAVREALLKEREKMRASIDGWRMRVEGIEAAVEGRADEEILSREAQDMWVACHALHGVLTGNGATPPLARYLNSFEEAAQPSSRPVLQLFLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVSWLRSLILLTPSHLIECDTEIDPESDEIDTNQVIASAELAIWRQDFDLAIRLLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSSKTAGSI 687
The following BLAST results are available for this feature:
BLAST of MICOS complex subunit MIC60 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
IMMT4.964e-5733.17inner membrane mitochondrial protein [Source:HGNC ... [more]
IMMT8.344e-5726.89inner membrane mitochondrial protein [Source:HGNC ... [more]
IMMT1.318e-5633.17inner membrane mitochondrial protein [Source:HGNC ... [more]
IMMT7.160e-5633.17inner membrane mitochondrial protein [Source:HGNC ... [more]
IMMT8.829e-5633.17inner membrane mitochondrial protein [Source:HGNC ... [more]
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BLAST of MICOS complex subunit MIC60 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
immt-16.606e-5829.83MICOS complex subunit MIC60-1 [Source:UniProtKB/S... [more]
immt-23.332e-3124.19MICOS complex subunit MIC60-2 [Source:UniProtKB/S... [more]
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BLAST of MICOS complex subunit MIC60 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Mitofilin7.033e-4625.51gene:FBgn0019960 transcript:FBtr0290271[more]
Mitofilin7.033e-4625.51gene:FBgn0019960 transcript:FBtr0335199[more]
Mitofilin5.907e-4425.25gene:FBgn0019960 transcript:FBtr0335200[more]
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BLAST of MICOS complex subunit MIC60 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
immt8.255e-5929.31inner membrane protein, mitochondrial (mitofilin) ... [more]
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BLAST of MICOS complex subunit MIC60 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
stau14.572e-6128.57staufen double-stranded RNA binding protein 1 [Sou... [more]
stau11.274e-6028.72staufen double-stranded RNA binding protein 1 [Sou... [more]
stau15.320e-6029.82staufen double-stranded RNA binding protein 1 [Sou... [more]
stau11.547e-5929.82staufen double-stranded RNA binding protein 1 [Sou... [more]
stau12.577e-5829.95staufen double-stranded RNA binding protein 1 [Sou... [more]
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BLAST of MICOS complex subunit MIC60 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Immt5.555e-5827.03inner membrane protein, mitochondrial [Source:MGI ... [more]
Immt1.878e-5727.08inner membrane protein, mitochondrial [Source:MGI ... [more]
Immt2.664e-5428.49inner membrane protein, mitochondrial [Source:MGI ... [more]
Immt3.121e-5428.88inner membrane protein, mitochondrial [Source:MGI ... [more]
Immt1.856e-2834.70inner membrane protein, mitochondrial [Source:MGI ... [more]
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BLAST of MICOS complex subunit MIC60 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q22505|IMMT1_CAEEL8.403e-5729.83MICOS complex subunit MIC60-1 OS=Caenorhabditis el... [more]
sp|Q16891|MIC60_HUMAN4.862e-5533.17MICOS complex subunit MIC60 OS=Homo sapiens OX=960... [more]
sp|Q8CAQ8|MIC60_MOUSE1.864e-5328.49MICOS complex subunit Mic60 OS=Mus musculus OX=100... [more]
sp|P91928|MIC60_DROME7.050e-4525.51MICOS complex subunit Mic60 OS=Drosophila melanoga... [more]
sp|Q3KR86|MIC60_RAT1.129e-3424.61MICOS complex subunit Mic60 (Fragment) OS=Rattus n... [more]
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BLAST of MICOS complex subunit MIC60 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2T7PBT78.124e-8529.48MICOS complex subunit MIC60 OS=Pomacea canaliculat... [more]
V3ZVC87.739e-8232.82MICOS complex subunit MIC60 (Fragment) OS=Lottia g... [more]
K1QNN93.198e-7532.08MICOS complex subunit MIC60 OS=Crassostrea gigas O... [more]
A0A3S1B2R08.444e-7333.01MICOS complex subunit MIC60 OS=Elysia chlorotica O... [more]
W4XLS82.606e-7234.23Uncharacterized protein OS=Strongylocentrotus purp... [more]
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BLAST of MICOS complex subunit MIC60 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
immt2.070e-6029.24inner membrane mitochondrial protein [Source:NCBI ... [more]
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BLAST of MICOS complex subunit MIC60 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSPMAT00000004532.12.530e-4929.26pep scaffold:Pmarinus_7.0:GL477554:141141:147823:1... [more]
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BLAST of MICOS complex subunit MIC60 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of MICOS complex subunit MIC60 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO310804.073e-5126.37Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of MICOS complex subunit MIC60 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
immt3.157e-5829.41inner membrane mitochondrial protein [Source:NCBI ... [more]
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BLAST of MICOS complex subunit MIC60 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000066687.10.000e+099.57SMESG000066687.1[more]
SMESG000066687.10.000e+098.56SMESG000066687.1[more]
SMESG000066687.10.000e+098.13SMESG000066687.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30021516 ID=SMED30021516|Name=MICOS complex subunit MIC60|organism=Schmidtea mediterranea sexual|type=transcript|length=2444bp
TGGAACTATTGTTTTAATATATTCATGAGGTTTGCAAATTAAATTATTAC
AATTTTCGATATTAATGCTCAGAATTAATCCCAGAAATAAATTAGTGACT
TTAGAATATGTAATTAAACGATTCAATTCTAAATCAACAAATTTGCAAAG
TACATCAGAAAAATCACACAAGCAAAAATATGAATATCAGCAGTCAGCCT
TTGTTCCAATTTTCTTAGGAATTTCATCAATTACTTTATTAGGAACTGGA
TTGTCATATTATTACAATGATGATTTTCGAGAAAAGGTTGCGCCGTATCT
ACCAAAGCGAACTAAACAATTTCTAGACGAATATTTTGATATACCAATTA
CTGATAGAATAATGAAAAAATGGGATAGTTTCAATTTCTTCGATAAATTA
TCAATAAAAAGCAATAAAATGGAGTCTTTTACAAGTCGCTTTAAGGGATC
CAAGGAATCTAATGGGCCTGAATCGAGTCAGAAAGAATCCAAACCTTTTA
TGAATGAGTCCGTAAAGAAAGTACCACGTACGCCTTCAGAGAAAATCAAA
GATGATGTAGAAAAAGAAGCGGAAAGATTAAAAAAGTTAAACGAAGTATT
CTCCAATAAACTTTCAAATCAAATAGACTCAGTGGAAGCAGCTTCAACAA
GTGTCATACTCCATCTAATGGAATATGCTGATAAAATCCAGGACCACAGC
CAGAAATTGAAACGAGCTATCGAAGATGATGGGACCACAATTCCGAATCC
TTGGGAAGAAGTCAACGAGAGCAATCACCTTCAACAAACTGCTAAAACAA
AATCCGATAAAGAAATGAAACGACTCGAATTGGCGATCAAGCAACTGGAA
TTATCGATAAACGAAGGCAATCATTCAGAAGACCTGAAGTCCAATCCATC
AATCCACACCGGCCAGGAAGTGTTATCAAGCACCAATTATCGAATCAAAC
AAAAACTAGCTGATATAGAAAAGGCTCAATTCAATGCTCAAATCACTAAT
CAATACAAAGAATTGATCCATCAGGGTCAAGAGCGGTTTAAACAGGAATT
GTCCAGCTTGAATCCAAACGTGTCTAACTGGACAAAGAAGCATACCGATA
AATTATCGAACGATGACCTCAACGCAATGATTGTGCACGCCCATCGTAGA
ATGCACCAATTACAAGCGAGAATCGCAGAACTGGAATCGATGGAAGTGAT
CAGATTGGATGCAGCATTAACGGAACAGAGAAAAAAGGACGAGATATCAG
CAGAAGGAAAGGTGCAAATGGAACTGGAAAGGGAACGATCAAAGAAGTCA
ATAGAATTTCAAGAGGAACTGGATAAGATGAAGCAACATCAAGAGGTGGA
GTTGCGACGGGCACTGACTAGACAGGCCTCGGCACACAATGAGCACATAA
ACCAGCTGTTGAAAATCCAAAAGGACGAGATCGATAAGCAGCACAGTTTG
GCGGTGCGAGAGGCGCTGCTGAAGGAGCGCGAGAAGATGCGTGCATCAAT
CGATGGGTGGCGGATGCGAGTGGAGGGCATTGAGGCAGCGGTGGAGGGCC
GTGCTGACGAGGAGATCCTGTCCCGGGAGGCACAGGACATGTGGGTGGCC
TGTCACGCGCTCCATGGAGTCCTCACTGGCAACGGTGCCACTCCTCCGCT
TGCCCGCTACTTGAACTCATTTGAGGAAGCAGCGCAACCGTCGAGCAGAC
CCGTGTTGCAACTGTTTCTCGAATCGATACCGAAATGCGCCCTGGAGCAA
GGCGTTTGCACCCAGAACCTGTTGACAAAGCGATTCGATAAGATCAAACG
CGTCTGTCGTCGGGTAGCAATGATAGATGAGACGAGCGCATCGTTGCCAA
TGTACATCGTGTCCTGGTTACGCTCCCTCATCCTGCTGACTCCGTCCCAT
CTCATCGAATGCGACACGGAAATCGATCCAGAATCCGATGAGATCGACAC
CAATCAGGTCATTGCCAGTGCTGAGTTGGCTATTTGGCGCCAGGATTTCG
ATCTGGCCATCCGGTTGCTGAATCTGCTGAAGGGGATGCCGCGCGTCATC
GTGCACGACTGGATAACTGACGCCAGGATTTACCTGGAAACCAAGCTGGC
AGCGGACGCGCTCAGCAGCTACACATCATCAAAAACAGCTGGCAGCATTC
CACCCCTCATGCCGCAGCCTCTAGAGTAGCCGTAACCAAGGATATAATAA
ATAAATCAATAAATATATATATTTATATGAATATTGACGGTGGATATTAG
TTTTCAAATAGAAGATGTTTCATTTTGTTCTTTTGTCAATTTCCGTTTTT
ATTGATTATTTATAATTTTTCACCCATTCATTCGCTTGTCTCATTTTTAT
ATATCTTTGATGAATCAATAAATATTTATTTGTTTCTAGGTGGCTAATTG
ATAAAGTACAAGTACATTTTGGGAGGTGAAATCCTCTCCCTCCC
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protein sequence of SMED30021516-orf-1

>SMED30021516-orf-1 ID=SMED30021516-orf-1|Name=SMED30021516-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=705bp
MLRINPRNKLVTLEYVIKRFNSKSTNLQSTSEKSHKQKYEYQQSAFVPIF
LGISSITLLGTGLSYYYNDDFREKVAPYLPKRTKQFLDEYFDIPITDRIM
KKWDSFNFFDKLSIKSNKMESFTSRFKGSKESNGPESSQKESKPFMNESV
KKVPRTPSEKIKDDVEKEAERLKKLNEVFSNKLSNQIDSVEAASTSVILH
LMEYADKIQDHSQKLKRAIEDDGTTIPNPWEEVNESNHLQQTAKTKSDKE
MKRLELAIKQLELSINEGNHSEDLKSNPSIHTGQEVLSSTNYRIKQKLAD
IEKAQFNAQITNQYKELIHQGQERFKQELSSLNPNVSNWTKKHTDKLSND
DLNAMIVHAHRRMHQLQARIAELESMEVIRLDAALTEQRKKDEISAEGKV
QMELERERSKKSIEFQEELDKMKQHQEVELRRALTRQASAHNEHINQLLK
IQKDEIDKQHSLAVREALLKEREKMRASIDGWRMRVEGIEAAVEGRADEE
ILSREAQDMWVACHALHGVLTGNGATPPLARYLNSFEEAAQPSSRPVLQL
FLESIPKCALEQGVCTQNLLTKRFDKIKRVCRRVAMIDETSASLPMYIVS
WLRSLILLTPSHLIECDTEIDPESDEIDTNQVIASAELAIWRQDFDLAIR
LLNLLKGMPRVIVHDWITDARIYLETKLAADALSSYTSSKTAGSIPPLMP
QPLE*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000026gut
PLANA:0000429neoblast
Vocabulary: INTERPRO
TermDefinition
IPR019133Mt-IM_prot_Mitofilin
Vocabulary: cellular component
TermDefinition
GO:0005739mitochondrion
GO:0005743mitochondrial inner membrane
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 158..182
NoneNo IPR availableCOILSCoilCoilcoord: 201..221
NoneNo IPR availableCOILSCoilCoilcoord: 244..271
NoneNo IPR availableCOILSCoilCoilcoord: 356..376
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 125..144
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 145..164
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 125..164
NoneNo IPR availableTMHMMTMhelixcoord: 45..67
IPR019133Mitochondrial inner membrane protein MitofilinPFAMPF09731Mitofilincoord: 60..687
e-value: 5.5E-98
score: 329.4
IPR019133Mitochondrial inner membrane protein MitofilinPANTHERPTHR15415MITOFILINcoord: 28..693