Metaxin 1
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30021481 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 2
Homology
BLAST of Metaxin 1 vs. Ensembl Human
Match: MTX1 (metaxin 1 [Source:HGNC Symbol;Acc:HGNC:7504]) HSP 1 Score: 116.316 bits (290), Expect = 3.586e-29 Identity = 87/305 (28.52%), Postives = 134/305 (43.93%), Query Frame = 2
Query: 107 MNLYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPFLQHSLNSSVGLKH-IIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSYYHHRALTNPNRAPNEIVSANENTLRGKVRVFLTENWIQIRNSSIFVLFVSTMMICYAKSTKVV 1018
M L+ W L S+D +SLAV+TY + AP+ + PW PS +LP L+ S + + H II + RKE Y +Y+L+ A S + + L+P + + W + NY VTR +AEA+ FP++ F M+ + RL T EE ++ LY A+ CLT L L ++FF + P +DA ++ YL +L L VH++ + + I Y+ P P A T E + RN + VL M+ YA + +V
Sbjct: 5 MELFCWSGGWGLPSVDLDSLAVLTYARFTGAPLKVHKISNPWQSPSGTLPALRTSHGEVISVPHKIITHLRKEKYNADYDLSARQGADTLAFMSLLEEKLLPVLVHTFWIDTKNYVEVTRKWYAEAMPFPLNFFLPGRMQRQ-----YMERLQLLTGEHRPEDEEELEKELYREARECLTLLSQRLGSQKFFFGDAPASLDAFVFSYLALLLQAKLPSGKLQVHLRGLHNLCAYCTHILSLYFPWDGAEVP---PQRQTPAGPET---------EEEPYRRRNQILSVLAGLAAMVGYALLSGIV 292
BLAST of Metaxin 1 vs. Ensembl Human
Match: MTX1 (metaxin 1 [Source:HGNC Symbol;Acc:HGNC:7504]) HSP 1 Score: 114.775 bits (286), Expect = 8.525e-28 Identity = 87/305 (28.52%), Postives = 134/305 (43.93%), Query Frame = 2
Query: 107 MNLYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPFLQHSLNSSVGLKH-IIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSYYHHRALTNPNRAPNEIVSANENTLRGKVRVFLTENWIQIRNSSIFVLFVSTMMICYAKSTKVV 1018
M L+ W L S+D +SLAV+TY + AP+ + PW PS +LP L+ S + + H II + RKE Y +Y+L+ A S + + L+P + + W + NY VTR +AEA+ FP++ F M+ + RL T EE ++ LY A+ CLT L L ++FF + P +DA ++ YL +L L VH++ + + I Y+ P P A T E + RN + VL M+ YA + +V
Sbjct: 154 MELFCWSGGWGLPSVDLDSLAVLTYARFTGAPLKVHKISNPWQSPSGTLPALRTSHGEVISVPHKIITHLRKEKYNADYDLSARQGADTLAFMSLLEEKLLPVLVHTFWIDTKNYVEVTRKWYAEAMPFPLNFFLPGRMQRQ-----YMERLQLLTGEHRPEDEEELEKELYREARECLTLLSQRLGSQKFFFGDAPASLDAFVFSYLALLLQAKLPSGKLQVHLRGLHNLCAYCTHILSLYFPWDGAEVP---PQRQTPAGPET---------EEEPYRRRNQILSVLAGLAAMVGYALLSGIV 441
BLAST of Metaxin 1 vs. Ensembl Human
Match: MTX3 (metaxin 3 [Source:HGNC Symbol;Acc:HGNC:24812]) HSP 1 Score: 105.531 bits (262), Expect = 2.825e-25 Identity = 78/267 (29.21%), Postives = 122/267 (45.69%), Query Frame = 2
Query: 107 MNLYVWPPLGALESIDPESLAVITYVKIAQAP--VNIFTNIRPWSCPSYSLPFLQHSLNSSVGLKHIIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSYYHHRALTNPNRAPNEIVSANENTL 901
+ L W L S+ ESL V+ Y K + AP VN+ N W +P L + I+ + RK+ Y +Y L+ + A + + + L+PAV + W S NY +VT+ FA + FP+SL M A ++IL +R + L E V+ +Y AK CL L L +FF + P+ +DA ++G+L P+ + + L H+KQ + + I SY+ +L + A E V AN L
Sbjct: 5 LELSCWGGGWGLPSVHSESLVVMAYAKFSGAPLKVNVIDNT--WRGSRGDVPILTTEDDMVSQPAKILNFLRKQKYNADYELSAKQGADTLAYIALLEEKLLPAVLHTFWVESDNYFTVTKPWFASQIPFPLSLILPGRMSKGALNRILLTRGQPPLYH---LRE--VEAQIYRDAKECLNLLSNRLGTSQFFFGDTPSTLDAYVFGFLAPLYKVRFPKVQLQEHLKQLSNLCRFCDDILSSYFRL-SLGGISPAGQETVDANLQKL 263
BLAST of Metaxin 1 vs. Ensembl Human
Match: MTX3 (metaxin 3 [Source:HGNC Symbol;Acc:HGNC:24812]) HSP 1 Score: 102.834 bits (255), Expect = 7.104e-25 Identity = 68/243 (27.98%), Postives = 111/243 (45.68%), Query Frame = 2
Query: 107 MNLYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPFLQHSLNSSVGLKHIIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSYYH 835
+ L W L S+ ESL V+ Y K + AP+ + W +P L + I+ + RK+ Y +Y L+ + A + + + L+PAV + W S NY +VT+ FA + FP+SL M A ++IL +R + L E V+ +Y AK CL L L +FF + P+ +DA ++G+L P+ + + L H+KQ + + I SY+
Sbjct: 5 LELSCWGGGWGLPSVHSESLVVMAYAKFSGAPLKVNVIDNTWRGSRGDVPILTTEDDMVSQPAKILNFLRKQKYNADYELSAKQGADTLAYIALLEEKLLPAVLHTFWVESDNYFTVTKPWFASQIPFPLSLILPGRMSKGALNRILLTRGQPPLYH---LRE--VEAQIYRDAKECLNLLSNRLGTSQFFFGDTPSTLDAYVFGFLAPLYKVRFPKVQLQEHLKQLSNLCRFCDDILSSYFR 242
BLAST of Metaxin 1 vs. Ensembl Human
Match: MTX3 (metaxin 3 [Source:HGNC Symbol;Acc:HGNC:24812]) HSP 1 Score: 88.1965 bits (217), Expect = 1.512e-19 Identity = 59/197 (29.95%), Postives = 96/197 (48.73%), Query Frame = 2
Query: 299 IIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSYYHHRALTNPNRAPNEIVSAN 889
I+ + RK+ Y +Y L+ + A + + + L+PAV + W S NY +VT+ FA + FP+SL M A ++IL +R + L E V+ +Y AK CL L L +FF + P+ +DA ++G+L P+ + + L H+KQ + + I SY+ +L + A E V AN
Sbjct: 8 ILNFLRKQKYNADYELSAKQGADTLAYIALLEEKLLPAVLHTFWVESDNYFTVTKPWFASQIPFPLSLILPGRMSKGALNRILLTRGQPPLYH---LRE--VEAQIYRDAKECLNLLSNRLGTSQFFFGDTPSTLDAYVFGFLAPLYKVRFPKVQLQEHLKQLSNLCRFCDDILSSYFRL-SLGGISPAGQETVDAN 198
BLAST of Metaxin 1 vs. Ensembl Celegans
Match: mtx-1 (Metaxin-1 homolog [Source:UniProtKB/Swiss-Prot;Acc:O45503]) HSP 1 Score: 105.145 bits (261), Expect = 1.216e-25 Identity = 68/246 (27.64%), Postives = 120/246 (48.78%), Query Frame = 2
Query: 107 MNLYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPFLQHSLNSS---VGLKHIIPYFRK--ENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSY 829
M L++WP L +ID SL + K+ +PV + + RPW PS LP + + + + + +K ++ ++ +LT + A+L S +H +L PAV + W NYN+VT+ +A + FP +L++ + KA ++L+ K E +K+A L +L L + +FF NKPT +DA+++GYL P+L + D L V + C ++ + ++ Y
Sbjct: 1 MELHIWPSDFGLPTIDVVSLQFLACSKMCASPVRVIQSTRPWRSPSGELPMVAQTEGEAKPVTDFEKFVDILKKCGQDVVIDADLTTIEKAQLDAFSCYLHHNLYPAVMHTFWTDELNYNTVTQYWYASHLHFPYNLYYLEKRRKKAL-RLLA----------GKNDTEILKEAFM-----ALNTLSTKLGDNKFFCGNKPTSLDALVFGYLAPLLRVPLPNDRLQVQLSACPNLVRFVETVSSIY 230
BLAST of Metaxin 1 vs. Ensembl Celegans
Match: mtx-2 (Metaxin-2 homolog [Source:UniProtKB/Swiss-Prot;Acc:P34599]) HSP 1 Score: 59.6918 bits (143), Expect = 4.716e-10 Identity = 44/230 (19.13%), Postives = 100/230 (43.48%), Query Frame = 2
Query: 158 ESLAVITYVKIAQAPVNIFTNIRP---WSCPSYSLPFLQHSLNSSVGLKHIIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSYYHH 838
+ LAV T++++ P N+ RP + P +P L+ + G I+ + K+ + +L++ +A + S I L +++W H Y+ VT+ + +P+S + + K ++ + +T+ D + A + +L L +++ + PT DA+L+G+++ ++ + L + +K+ + ++E I Q Y+
Sbjct: 44 DCLAVQTFLRMTSLPFNV--RQRPNVDFISPDGVVPLLKINKTLITGFNAIVDFVHKKGVTLTSHLSETQVADMRANISMIEHLLTTVEKFVLWNHDETYDKVTKLRYGSVYHWPLSSVLPFVKRRKILEELSDKDWDTKTM-----------DEVGEQADKVFRALSAQLGSQKYLTGDLPTEADALLFGHMYTLITVRLPLTNITNILKKYSNLIEFTKRIEQQYFKQ 260
BLAST of Metaxin 1 vs. Ensembl Celegans
Match: mtx-2 (Metaxin-2 homolog [Source:UniProtKB/Swiss-Prot;Acc:P34599]) HSP 1 Score: 59.6918 bits (143), Expect = 4.716e-10 Identity = 44/230 (19.13%), Postives = 100/230 (43.48%), Query Frame = 2
Query: 158 ESLAVITYVKIAQAPVNIFTNIRP---WSCPSYSLPFLQHSLNSSVGLKHIIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSYYHH 838
+ LAV T++++ P N+ RP + P +P L+ + G I+ + K+ + +L++ +A + S I L +++W H Y+ VT+ + +P+S + + K ++ + +T+ D + A + +L L +++ + PT DA+L+G+++ ++ + L + +K+ + ++E I Q Y+
Sbjct: 44 DCLAVQTFLRMTSLPFNV--RQRPNVDFISPDGVVPLLKINKTLITGFNAIVDFVHKKGVTLTSHLSETQVADMRANISMIEHLLTTVEKFVLWNHDETYDKVTKLRYGSVYHWPLSSVLPFVKRRKILEELSDKDWDTKTM-----------DEVGEQADKVFRALSAQLGSQKYLTGDLPTEADALLFGHMYTLITVRLPLTNITNILKKYSNLIEFTKRIEQQYFKQ 260
BLAST of Metaxin 1 vs. Ensembl Fly
Match: CG9393 (gene:FBgn0037710 transcript:FBtr0332808) HSP 1 Score: 68.9366 bits (167), Expect = 8.876e-13 Identity = 59/271 (21.77%), Postives = 115/271 (42.44%), Query Frame = 2
Query: 113 LYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPFLQHSLNSSVGLKHIIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSYYHHRALTNPNRAPNEIVSANENTLRGKVRVFL 925
LYV+ L SID E L + ++ + P+++ T+ P + LP+LQ G + I E Y ++ +L+ + ++ + +L Y ++ N+++ TR L+A+ FP + ++ + + +A ++ F +K E D L AK+ + L L K +F + + DA++Y YL I + + L H+K C ++ + I + + ++ + S E +L R FL
Sbjct: 9 LYVYKGEYGLPSIDFECLRALCLLRFTRCPMDVQTSSNPLRSGAGKLPYLQIGNQKFAGYRQIKRVLDLEGYPIDAHLSTKQKHLSTAYANWVFTNLHAYYHYFLFGEPHNFDTTTRGLYAKRTPFPFNFYYPSSYQREACD-VVQVMAGFDVNDKLDKHE---GDYLVVNAKKVVNLLSRKLGRKVWFFGDTYSEFDAIVYSYLAIIFKIALPNNPLQNHIKGCQNLVNFINRITKDIFRIEGYSSVKLT--KTPSGTEASLTASERKFL 273
BLAST of Metaxin 1 vs. Ensembl Fly
Match: CG9393 (gene:FBgn0037710 transcript:FBtr0082113) HSP 1 Score: 68.1662 bits (165), Expect = 1.586e-12 Identity = 59/271 (21.77%), Postives = 115/271 (42.44%), Query Frame = 2
Query: 113 LYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPFLQHSLNSSVGLKHIIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSYYHHRALTNPNRAPNEIVSANENTLRGKVRVFL 925
LYV+ L SID E L + ++ + P+++ T+ P + LP+LQ G + I E Y ++ +L+ + ++ + +L Y ++ N+++ TR L+A+ FP + ++ + + +A ++ F +K E D L AK+ + L L K +F + + DA++Y YL I + + L H+K C ++ + I + + ++ + S E +L R FL
Sbjct: 9 LYVYKGEYGLPSIDFECLRALCLLRFTRCPMDVQTSSNPLRSGAGKLPYLQIGNQKFAGYRQIKRVLDLEGYPIDAHLSTKQKHLSTAYANWVFTNLHAYYHYFLFGEPHNFDTTTRGLYAKRTPFPFNFYYPSSYQREACD-VVQVMAGFDVNDKLDKHE---GDYLVVNAKKVVNLLSRKLGRKVWFFGDTYSEFDAIVYSYLAIIFKIALPNNPLQNHIKGCQNLVNFINRITKDIFRIEGYSSVKLT--KTPSGTEASLTASERKFL 273
BLAST of Metaxin 1 vs. Ensembl Zebrafish
Match: mtx1b (metaxin 1b [Source:ZFIN;Acc:ZDB-GENE-021210-1]) HSP 1 Score: 124.02 bits (310), Expect = 3.295e-32 Identity = 84/305 (27.54%), Postives = 143/305 (46.89%), Query Frame = 2
Query: 107 MNLYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPFLQHSLNSSVGL-KHIIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSYYHHRALTNPNRAPNEIVSANENTLRGKVRVFLTENWIQIRNSSIFVLFVSTMMICYAKSTKVV 1018
+ L+ W L S+D + LAV+ Y K A AP+ + PW P+ SLP L+ S+ II + RK+ Y +Y+L+ ++ A S + + L+PA+ Y +W S NY VTR +AE + FP++ N M S+ K+ R + +L +E +DA C+T L L ++FF + P+ +DA ++ +L P+L + L H+ N + + +I Y+ ++ AP + ++ F E ++ RN + VLF M+ YA T ++
Sbjct: 5 LELFCWKGDYGLPSVDVDCLAVLAYAKFAGAPIKVHKITNPWRSPTGSLPALKTREEGSISQPSKIIIHLRKQKYNADYDLSAKEGADTLAFVSLLEEKLLPALVYTLWIDSKNYVDVTRCWYAENIPFPLNFLLPNRMHSQQLEKLRLVRGDPVLEPGEQLEKELYRDAF-----ECMTLLSQRLGSQKFFFGDSPSSLDAYVFAHLAPLLKIKLPNGKLQQHLNSLNNLEQFCSNILLLYFP----SDQREAPARKIHVQSDS-----SDFDNEPHMR-RNQILSVLFAVGAMLGYAVLTGII 294
BLAST of Metaxin 1 vs. Ensembl Zebrafish
Match: mtx1a (metaxin 1a [Source:ZFIN;Acc:ZDB-GENE-060606-2]) HSP 1 Score: 104.76 bits (260), Expect = 4.251e-25 Identity = 62/212 (29.25%), Postives = 104/212 (49.06%), Query Frame = 2
Query: 113 LYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPFLQHSLNSSVGL-KHIIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHL 745
L+ W L S++ + L V+ Y + A AP+ I PW P+ SLP L+ S II RK+ + +Y+L+ ++ A S + + L+PA+ Y +W NY VTR + E + FP++ F M+++ ++ R N + EE K+ LY+ A CL L L +FF + P+ +DA ++G+L P+ +
Sbjct: 7 LFCWKAGLGLPSVNTDCLIVLAYARFAGAPLKIHKISNPWRSPTGSLPALRTKDEGSCSQPSQIIIQLRKQKFNADYDLSAKEGADTLAFISLLEERLLPALIYALWIDPKNYVEVTRRWYGENMSFPLNFFLPGRMQNRQLERLRLIRGN----GTLEAGEEAEKE-LYHDALECLNLLSQRLGSNKFFFGDSPSSLDAYVFGHLAPLFKI 213
BLAST of Metaxin 1 vs. Ensembl Zebrafish
Match: mtx3 (metaxin 3 [Source:NCBI gene;Acc:402916]) HSP 1 Score: 93.9745 bits (232), Expect = 2.429e-21 Identity = 62/249 (24.90%), Postives = 116/249 (46.59%), Query Frame = 2
Query: 107 MNLYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPFLQHSLNSSVGLKHIIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSYYHHRALTN 853
+ L W L S+ +SL V+ Y K A A + + W + S+P + + + I+ + RK+ + ++ LT + A + + + L PA+ + W + NY ++TR F FP++ F S A S+IL ++ +N +TE V+ +Y+ AK CL L + L FF + PT +DA ++G++ P++ L H+ Q + + + +I ++Y+ + N
Sbjct: 5 IELLCWGGDWDLPSVQTDSLTVLAYAKFAGAELTVKFVDWTWRTITASVPQIHYEGTTVTEPTQILNFLRKQRFNADFELTAKQGADTMAYIALLEEKLRPALLHTFWVDAENYANLTRPWFTSHSPFPLNFFVPGRQASLALSRILLTKAESPLLN---ITE--VEGKIYSEAKECLNLLSHRLGNFNFFFGDTPTSLDAFVFGHIAPLIKAPLPSGQLQKHLNQLDNLCQFCNTILKNYFTDATVEN 248
BLAST of Metaxin 1 vs. Ensembl Zebrafish
Match: mtx3 (metaxin 3 [Source:NCBI gene;Acc:402916]) HSP 1 Score: 93.9745 bits (232), Expect = 2.649e-21 Identity = 62/249 (24.90%), Postives = 116/249 (46.59%), Query Frame = 2
Query: 107 MNLYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPFLQHSLNSSVGLKHIIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSYYHHRALTN 853
+ L W L S+ +SL V+ Y K A A + + W + S+P + + + I+ + RK+ + ++ LT + A + + + L PA+ + W + NY ++TR F FP++ F S A S+IL ++ +N +TE V+ +Y+ AK CL L + L FF + PT +DA ++G++ P++ L H+ Q + + + +I ++Y+ + N
Sbjct: 9 IELLCWGGDWDLPSVQTDSLTVLAYAKFAGAELTVKFVDWTWRTITASVPQIHYEGTTVTEPTQILNFLRKQRFNADFELTAKQGADTMAYIALLEEKLRPALLHTFWVDAENYANLTRPWFTSHSPFPLNFFVPGRQASLALSRILLTKAESPLLN---ITE--VEGKIYSEAKECLNLLSHRLGNFNFFFGDTPTSLDAFVFGHIAPLIKAPLPSGQLQKHLNQLDNLCQFCNTILKNYFTDATVEN 252
BLAST of Metaxin 1 vs. Ensembl Zebrafish
Match: mtx2 (metaxin 2 [Source:ZFIN;Acc:ZDB-GENE-021210-2]) HSP 1 Score: 61.2326 bits (147), Expect = 3.186e-10 Identity = 48/228 (21.05%), Postives = 97/228 (42.54%), Query Frame = 2
Query: 161 SLAVITYVKIAQAPVNIFTNIRP-WSCPSYSLPFLQHSLNSSVGLKHIIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSYYHHR 841
SLAV T++++ PV + + PS +PF+Q L I+ + + + + + L D A++ ++ L+ A Y+ W ++R ++ +P++ A K R + + + E V Y +C +L L + +F + +PT +DA+++G+L+ IL D L+ VK + ++ I Q+Y+ +
Sbjct: 41 SLAVQTFLRMCGLPVQVSCRANAEYMSPSGKVPFIQVGNQVVSELGPIVQFTKAKGHSLSDGLDDVQRAEMKAYMELVNNMLLTAELYIQWCDDFTATEISRPRYSSPYSWPLNHIL-------AYQKQWEVRRKMNAIGWSGKSLEQV----YEDVSQCCQALSQRLGTQPYFFNKQPTELDALVFGHLFTILTTQLTSDELVEKVKSYSNLLSFCHRIEQAYFKEQ 257
BLAST of Metaxin 1 vs. Ensembl Xenopus
Match: MTX3 (metaxin 3 [Source:NCBI gene;Acc:100493350]) HSP 1 Score: 103.99 bits (258), Expect = 1.274e-24 Identity = 68/248 (27.42%), Postives = 114/248 (45.97%), Query Frame = 2
Query: 104 FMNLYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPFLQHSLNSSVGLKHIIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAK-----LTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSYY 832
M L W L S+ PE L V+ Y + A AP+ + W+ P ++P L + +I+ + RK+ Y +Y L+ ++ + + + + L+PAV + W + NY SVTR +A FP++ + M A ++IL V K + LTE V+ LY AK CL + L ++F + PT +DA ++G+L P+ L H+KQ + + I +Y+
Sbjct: 23 MMELRCWGGDWGLPSVHPECLVVLAYARFAGAPLKVTPIDYTWASPKGTVPLLTSAGEDISQPANILNFLRKQKYNADYVLSAKEGSDTLAYIALLEEKLLPAVLHTFWVDTDNYCSVTRPWYASRTPFPLNYYLPGRMSRDALNRIL--------VTKGQPPLYCLTE--VEAQLYKDAKECLNLISNRLGTAQYFFGSTPTSLDAFVFGFLAPLYKAHLPKVNLQQHLKQLSNLCHFCDHILSTYF 260
BLAST of Metaxin 1 vs. Ensembl Xenopus
Match: dcaf17 (DDB1 and CUL4 associated factor 17 [Source:Xenbase;Acc:XB-GENE-6043873]) HSP 1 Score: 55.0694 bits (131), Expect = 4.452e-8 Identity = 50/247 (20.24%), Postives = 107/247 (43.32%), Query Frame = 2
Query: 110 NLYVWPPLGA---LESIDPESLAVITYVKIAQAPVNIFTNIRP-WSCPSYSLPFLQHSLNSSVG-LKHIIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSYYH 835
N ++ PL + L S + LAV ++K+ PV + + PS +PF+ H N + L I+ + + + + + L + A++ ++ L+ A Y+ W + +T+ ++ +P++ F K + K+ + +T+ + ++ +C +L L + +F + +PT +DA+++G+L+ IL D L VK + ++ I Q Y+
Sbjct: 21 NAALYQPLKSEQVLLSDNASCLAVQAFLKMCNLPVQVVCRANAEYMSPSGKVPFI-HVGNQVISELGPIVQFVKAKGHSLSDGLDEVQRAEMKAYMELVNNMLLTAELYIQWCDEATLEEITQPRYSFPYSWPLNYFLVFQRKWEIKRKMKAIGWATKTLEQ-----------VFEDVDQCCQALSQRLGTQPYFFNKQPTELDALVFGHLFTILTTQLTNDELQEKVKNYSNLIAFCRRIEQHYFE 255
BLAST of Metaxin 1 vs. Ensembl Mouse
Match: Mtx1 (metaxin 1 [Source:MGI Symbol;Acc:MGI:103025]) HSP 1 Score: 109.768 bits (273), Expect = 3.852e-26 Identity = 70/226 (30.97%), Postives = 109/226 (48.23%), Query Frame = 2
Query: 107 MNLYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPFLQHSLNSSVGLKH-IIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVK 781
M L+ W L S+D +SLAV+TY + AP+ I PW PS +LP L+ S + + H II + RKE Y +Y+L+ A S + + L+P + + W + NY VTR +AEA+ FP++ F M+ + RL EE ++ LY A+ CLT L L ++FF + P +DA ++ +L +L L H++
Sbjct: 149 MELFCWSGGWGLPSVDLDSLAVLTYTRFTGAPLKIHKTSNPWQSPSGTLPALRTSDGKVITVPHKIITHLRKEKYNADYDLSARQGADTLAFMSLLEEKLLPVLIHTFWIDAKNYVEVTRKWYAEAMPFPLNFFLPGRMQRQ-----YMERLQLLCGEHKSENEEELEKELYQEARECLTLLSQRLGSQKFFFGDAPASLDAFVFSHLALLLQAKLPSGKLQAHLR 369
BLAST of Metaxin 1 vs. Ensembl Mouse
Match: Mtx3 (metaxin 3 [Source:MGI Symbol;Acc:MGI:2686040]) HSP 1 Score: 98.5969 bits (244), Expect = 5.427e-23 Identity = 71/265 (26.79%), Postives = 116/265 (43.77%), Query Frame = 2
Query: 107 MNLYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPFLQHSLNSSVGLKHIIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSYYHHRALTNPNRAPNEIVSANENTL 901
M L W L S+ ESL V+ Y K + AP+ I W +P L + I+ + RK+ Y + L+ + A + + + L+PAV + W + NY +VT+ FA + FP+SL M A ++IL +R + + V+ +Y A+ CL L L +FF + P+ +DA ++G+L P+ + + L H+KQ + I SY+ + A E+V AN L
Sbjct: 5 MELSCWGGGWGLPSVHSESLVVLAYAKFSGAPLKINIIDNTWRGSRGDVPILTTEDSIVSKPAKILNFLRKQKYNADCELSAKQGADTLAYIALLEEKLLPAVLHTFWVENENYFTVTKPWFASRIPFPLSLILPGRMSRGALNRILLTRGEPPLYHVQE-----VEAQIYRDARECLNLLSNRLGTSQFFFGDTPSTLDAYVFGFLAPLYKVSFPKVHLQKHLKQLCNLCRFCDDILDSYFRP-GPGGVSPAGQEMVDANLQKL 263
BLAST of Metaxin 1 vs. Ensembl Mouse
Match: Mtx1 (metaxin 1 [Source:MGI Symbol;Acc:MGI:103025]) HSP 1 Score: 98.2117 bits (243), Expect = 6.855e-23 Identity = 79/291 (27.15%), Postives = 127/291 (43.64%), Query Frame = 2
Query: 149 IDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPFLQHSLNSSVGLKH-IIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSYYHHRALTNPNRAPNEIVSANENTLRGKVRVFLTENWIQIRNSSIFVLFVSTMMICYAKSTKVV 1018
+D +SLAV+TY + AP+ I PW PS +LP L+ S + + H II + RKE Y +Y+L+ A S + + L+P + + W + NY VTR +AEA+ FP++ F M+ + RL EE ++ LY A+ CLT L L ++FF + P +DA ++ +L +L L H++ + + I Y+ P P + +A E E + R + VL M+ YA + +V
Sbjct: 2 VDLDSLAVLTYTRFTGAPLKIHKTSNPWQSPSGTLPALRTSDGKVITVPHKIITHLRKE-YNADYDLSARQGADTLAFMSLLEEKLLPVLIHTFWIDAKNYVEVTRKWYAEAMPFPLNFFLPGRMQRQ-----YMERLQLLCGEHKSENEEELEKELYQEARECLTLLSQRLGSQKFFFGDAPASLDAFVFSHLALLLQAKLPSGKLQAHLRGLHNLCAYCTHILNLYFPRDGDEVP--LPRQTPAAPET----------EEEPYRRRTQILSVLAGLAAMVGYALLSGIV 274
BLAST of Metaxin 1 vs. Ensembl Mouse
Match: Mtx1 (metaxin 1 [Source:MGI Symbol;Acc:MGI:103025]) HSP 1 Score: 93.2041 bits (230), Expect = 3.758e-22 Identity = 49/147 (33.33%), Postives = 77/147 (52.38%), Query Frame = 2
Query: 107 MNLYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPFLQHSLNSSVGLKH-IIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKI 544
M L+ W L S+D +SLAV+TY + AP+ I PW PS +LP L+ S + + H II + RKE Y +Y+L+ A S + + L+P + + W + NY VTR +AEA+ FP++ F M+ + ++
Sbjct: 12 MELFCWSGGWGLPSVDLDSLAVLTYTRFTGAPLKIHKTSNPWQSPSGTLPALRTSDGKVITVPHKIITHLRKEKYNADYDLSARQGADTLAFMSLLEEKLLPVLIHTFWIDAKNYVEVTRKWYAEAMPFPLNFFLPGRMQRQYMERL 158
BLAST of Metaxin 1 vs. Ensembl Mouse
Match: Mtx1 (metaxin 1 [Source:MGI Symbol;Acc:MGI:103025]) HSP 1 Score: 91.6633 bits (226), Expect = 3.277e-20 Identity = 84/343 (24.49%), Postives = 133/343 (38.78%), Query Frame = 2
Query: 107 MNLYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSY--------------------------------------SLPFLQHSLNSSVGLKH-IIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSYYHHRALTNPNRAPNEIVSANENTLRGKVRVFLTENWIQIRNSSIFVLFVSTMMICYAKSTKVV 1018
M L+ W L S+D +SLAV+TY + AP+ I PW PS +LP L+ S + + H II + RKE Y +Y+L+ A S + + L+P + + W + NY VTR +AEA+ FP++ F M+ + RL EE ++ LY A+ CLT L L ++FF + P +DA ++ +L +L L H++ + + I Y+ P P + +A E E + R + VL M+ YA + +V
Sbjct: 10 MELFCWSGGWGLPSVDLDSLAVLTYTRFTGAPLKIHKTSNPWQSPSGIPEGQECARGGAGDRNAMQMSMTRQAGPCEYTSFSISGTLPALRTSDGKVITVPHKIITHLRKEKYNADYDLSARQGADTLAFMSLLEEKLLPVLIHTFWIDAKNYVEVTRKWYAEAMPFPLNFFLPGRMQRQ-----YMERLQLLCGEHKSENEEELEKELYQEARECLTLLSQRLGSQKFFFGDAPASLDAFVFSHLALLLQAKLPSGKLQAHLRGLHNLCAYCTHILNLYFPRDGDEVP--LPRQTPAAPET----------EEEPYRRRTQILSVLAGLAAMVGYALLSGIV 335
BLAST of Metaxin 1 vs. UniProt/SwissProt
Match: sp|Q27HK4|MTX1_PIG (Metaxin-1 OS=Sus scrofa OX=9823 GN=MTX1 PE=2 SV=1) HSP 1 Score: 114.775 bits (286), Expect = 5.852e-28 Identity = 75/241 (31.12%), Postives = 112/241 (46.47%), Query Frame = 2
Query: 107 MNLYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPFLQHSLNSSVGLKH-IIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYL-------WPILHLDYELDGLIVHVKQCNKIMEL 805
M L+ W L S+D +SLAV+TY + AP+ + PW PS +LP L+ S + + H II + RKE Y +Y+L+ A S + + L+P + + W + NY VTR +AEA+ FP++ F M+ + RL EE ++ LY A+ CLT L L ++FF + P +DA ++ YL P L L GL C I+ L
Sbjct: 5 MELFCWSGGWGLPSVDLDSLAVLTYARFTGAPLKVHKITNPWRSPSGTLPALRTSQGEVISVPHKIITHLRKEKYNADYDLSARQGADTLAFMSLLEEKLLPVLIHTFWVDAKNYVEVTRKWYAEAMPFPLNFFLPGRMQRQ-----YMERLQLLCGEHRPEEEEELEKELYQEARECLTLLSQRLGAQKFFFGDAPASLDAFVFSYLALLQQAKLPSGKLQAHLRGLHNLCAYCTHILSL 240
BLAST of Metaxin 1 vs. UniProt/SwissProt
Match: sp|Q2TBS1|MTX1_BOVIN (Metaxin-1 OS=Bos taurus OX=9913 GN=MTX1 PE=2 SV=1) HSP 1 Score: 112.849 bits (281), Expect = 2.832e-27 Identity = 85/305 (27.87%), Postives = 131/305 (42.95%), Query Frame = 2
Query: 107 MNLYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPFLQHSLNSSVGLKH-IIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSYYHHRALTNPNRAPNEIVSANENTLRGKVRVFLTENWIQIRNSSIFVLFVSTMMICYAKSTKVV 1018
M L+ W L S+D +SLAV+TY + AP+ + PW PS +LP L+ S + + H II + RKE Y +Y+L+ A S + + L+P + + W + NY VTR +AEA+ FP++ F M+ + RL EE ++ LY A+ CLT L L ++FF + P +DA ++ YL + L H++ + + I Y+ P P AN T E + RN + VL M YA + +V
Sbjct: 5 MELFCWSGGWGLPSVDLDSLAVLTYARFTGAPLKVHKITNPWRSPSGTLPALRTSHGEVISVPHRIITHLRKEKYNADYDLSARQGADTLAFMSLLEEKLLPVLKHTFWIDAKNYVEVTRKWYAEAMPFPLNFFLPGRMQRQ-----YMERLQLLCGEHRPEDEEELEKELYQEAQECLTLLSQRLGSQKFFFGDAPASLDAFVFSYLALLQQAKLPSGKLQAHLRGLHNLCAYCAHILSLYFPWEGAKAP---PPRQTPANPET---------EEEPYRRRNQILTVLAGLAAMAGYALLSGIV 292
BLAST of Metaxin 1 vs. UniProt/SwissProt
Match: sp|Q13505|MTX1_HUMAN (Metaxin-1 OS=Homo sapiens OX=9606 GN=MTX1 PE=1 SV=3) HSP 1 Score: 114.775 bits (286), Expect = 4.094e-27 Identity = 87/305 (28.52%), Postives = 134/305 (43.93%), Query Frame = 2
Query: 107 MNLYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPFLQHSLNSSVGLKH-IIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSYYHHRALTNPNRAPNEIVSANENTLRGKVRVFLTENWIQIRNSSIFVLFVSTMMICYAKSTKVV 1018
M L+ W L S+D +SLAV+TY + AP+ + PW PS +LP L+ S + + H II + RKE Y +Y+L+ A S + + L+P + + W + NY VTR +AEA+ FP++ F M+ + RL T EE ++ LY A+ CLT L L ++FF + P +DA ++ YL +L L VH++ + + I Y+ P P A T E + RN + VL M+ YA + +V
Sbjct: 154 MELFCWSGGWGLPSVDLDSLAVLTYARFTGAPLKVHKISNPWQSPSGTLPALRTSHGEVISVPHKIITHLRKEKYNADYDLSARQGADTLAFMSLLEEKLLPVLVHTFWIDTKNYVEVTRKWYAEAMPFPLNFFLPGRMQRQ-----YMERLQLLTGEHRPEDEEELEKELYREARECLTLLSQRLGSQKFFFGDAPASLDAFVFSYLALLLQAKLPSGKLQVHLRGLHNLCAYCTHILSLYFPWDGAEVP---PQRQTPAGPET---------EEEPYRRRNQILSVLAGLAAMVGYALLSGIV 441
BLAST of Metaxin 1 vs. UniProt/SwissProt
Match: sp|Q4R3I0|MTX1_MACFA (Metaxin-1 OS=Macaca fascicularis OX=9541 GN=MTX1 PE=2 SV=1) HSP 1 Score: 112.464 bits (280), Expect = 4.754e-27 Identity = 84/305 (27.54%), Postives = 134/305 (43.93%), Query Frame = 2
Query: 107 MNLYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPFLQHSLNSSVGLKH-IIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSYYHHRALTNPNRAPNEIVSANENTLRGKVRVFLTENWIQIRNSSIFVLFVSTMMICYAKSTKVV 1018
M L+ W L S+D +SLAV+TY + AP+ + PW PS +LP L+ S + + H II + RKE Y +Y+L+ A S + + L+P + + W + NY VTR +AEA+ FP++ F M+ + RL + EE ++ LY A+ CLT L L ++FF + P +DA ++ YL +L L H++ + + I Y+ P P + + E E + RN + VL M+ YA + +V
Sbjct: 5 MELFCWSGGWGLPSVDLDSLAVLTYARFTGAPLKVHKISNPWRSPSGTLPALRTSHGEVISVPHKIITHLRKEKYNADYDLSARQGADTLAFMSLLEEKLLPVLVHTFWIDTKNYVEVTRKWYAEAMPFPLNFFLPGRMQRQYM-----ERLELLSGEHMPEDEEELEKELYREARECLTLLSQRLGSQKFFFGDAPASLDAFVFSYLALLLQAKLPSGKLQAHLRGLHNLCAYCTHILSLYFPWDGAEVP--PPRQTPAGPET----------EEEPYRRRNQILSVLAGLAAMVGYALLSGIV 292
BLAST of Metaxin 1 vs. UniProt/SwissProt
Match: sp|P47802|MTX1_MOUSE (Metaxin-1 OS=Mus musculus OX=10090 GN=Mtx1 PE=1 SV=1) HSP 1 Score: 107.842 bits (268), Expect = 1.931e-25 Identity = 71/243 (29.22%), Postives = 113/243 (46.50%), Query Frame = 2
Query: 107 MNLYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPFLQHSLNSSVGL-KHIIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSYY 832
M L+ W L S+D +SLAV+TY + AP+ I PW PS +LP L+ S + + II + RKE Y +Y+L+ A S + + L+P + + W + NY VTR +AEA+ FP++ F M+ + RL EE ++ LY A+ CLT L L ++FF + P +DA ++ +L +L L H++ + + I Y+
Sbjct: 5 MELFCWSGGWGLPSVDLDSLAVLTYTRFTGAPLKIHKTSNPWQSPSGTLPALRTSDGKVITVPDKIITHLRKEKYNADYDLSARQGADTLAFMSLLEEKLLPVLIHTFWIDAKNYVEVTRKWYAEAMPFPLNFFLPGRMQRQ-----YMERLQLLCGEHKSENEEELEKELYQEARECLTLLSQRLGSQKFFFGDAPASLDAFVFSHLALLLQAKLPSGKLQAHLRGLHNLCAYCTHILNLYF 242
BLAST of Metaxin 1 vs. TrEMBL
Match: A0A087VYH0 (Metaxin 1 OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000092500 PE=4 SV=1) HSP 1 Score: 162.54 bits (410), Expect = 4.367e-43 Identity = 89/256 (34.77%), Postives = 137/256 (53.52%), Query Frame = 2
Query: 107 MNLYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPFLQHSLNSSVGLKHIIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYE--------LDGLIVHVKQCNKIMELLVSIHQSYYHHRALT 850
M+LYVWP +ES D + L VITY+++ + P+N+ + Y P L H N G+ II Y RKENYG+EY L+DE+LA L L +++ + + PA +L+W +S Y+S T L+ + + L++ + K S+L+ T K V+ LY RCLT+L YIL++K+FF +KP+ +DA L+G LWP+L+ D LI HV QC +++L + + + A T
Sbjct: 1 MDLYVWPDGRGIESFDSDCLVVITYLRLGKCPINLKSCRNSDKSCFYRTPLLIHGSNEVTGVSKIIAYLRKENYGLEYELSDEELACLESLVTSLERRVTPACRWLIWADTSVYHSYTSLLYRSNLSYLQGLWYPRRWRDKLIQSAEFSQLSLCTNGNTKNRYGDVEVTLYEGVIRCLTALSYILSDKQFFFGDKPSAIDAYLFGRLWPLLNYDCMRRQQESKICHRLINHVYQCENLLQLCCRVQRLCFPSAAST 256
BLAST of Metaxin 1 vs. TrEMBL
Match: A0A068X4V1 (Metaxin 1 OS=Echinococcus granulosus OX=6210 GN=EgrG_000092500 PE=4 SV=1) HSP 1 Score: 162.54 bits (410), Expect = 4.531e-43 Identity = 87/247 (35.22%), Postives = 133/247 (53.85%), Query Frame = 2
Query: 107 MNLYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPFLQHSLNSSVGLKHIIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYE--------LDGLIVHVKQCNKIMELLVSIHQ 823
M+LYVWP +ES D + L VITY+++ P+N+ + Y P L H N G+ II Y RKENYG+EY L+DE+LA+L L +++ + + PA +L+W +S Y+S T L+ + + L++ + K S+L T K V+ LY RCLT+L YIL++K+FF +KP+ +DA L+G LWP+L+ D LI HV QC +++L + +
Sbjct: 1 MDLYVWPDGRGIESFDSDCLVVITYLRLGGCPINLKSCRNSDKSYFYRTPLLIHGSNEVTGVSKIIEYLRKENYGLEYELSDEELARLESLVTSLERRVTPACRWLIWADTSVYHSYTSLLYRSNLSYLQGLWYPRRWRDKLIQSAEFSQLTLCTNGNTKNRYRDVELTLYEGVIRCLTALSYILSDKQFFFGDKPSAIDAYLFGRLWPLLNYDCMRRQQESKICHRLINHVYQCENLLQLCCRVQR 247
BLAST of Metaxin 1 vs. TrEMBL
Match: W6U974 (Metaxin-3 OS=Echinococcus granulosus OX=6210 GN=EGR_10109 PE=4 SV=1) HSP 1 Score: 162.54 bits (410), Expect = 4.749e-43 Identity = 87/247 (35.22%), Postives = 133/247 (53.85%), Query Frame = 2
Query: 107 MNLYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPFLQHSLNSSVGLKHIIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYE--------LDGLIVHVKQCNKIMELLVSIHQ 823
M+LYVWP +ES D + L VITY+++ P+N+ + Y P L H N G+ II Y RKENYG+EY L+DE+LA+L L +++ + + PA +L+W +S Y+S T L+ + + L++ + K S+L T K V+ LY RCLT+L YIL++K+FF +KP+ +DA L+G LWP+L+ D LI HV QC +++L + +
Sbjct: 1 MDLYVWPDGRGIESFDSDCLVVITYLRLGGCPINLKSCRNSDKSYFYRTPLLIHGSNEVTGVSKIIEYLRKENYGLEYELSDEELARLESLVTSLERRVTPACRWLIWADTSVYHSYTSLLYRSNLSYLQGLWYPRRWRDKLIQSAEFSQLTLCTNGNTKNRYRDVELTLYEGVIRCLTALSYILSDKQFFFGDKPSAIDAYLFGRLWPLLNYDCMRRQQESKICHRLINHVYQCENLLQLCCRVQR 247
BLAST of Metaxin 1 vs. TrEMBL
Match: A0A5K3F6V5 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1) HSP 1 Score: 157.147 bits (396), Expect = 4.716e-41 Identity = 84/272 (30.88%), Postives = 150/272 (55.15%), Query Frame = 2
Query: 107 MNLYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPFLQHSLNSSVGLKHIIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDY-------ELDGLIVHVKQCNKIMELLVSIHQSYYHHRA---LTNPNRAPNEIVSANE 892
M+L++WP ++S D + L +ITY+++ + P+N+F++ P S+P L H N + II Y RKENYG+EY L+DE+LA+L L +++ + + PA +L+W ++ YNS T L+ + + L+ + + S+L+ + + +K + V+ +L+ A+RCLT+L Y+L +K FF +P+ +DA ++G LWP+L+ D + LI HV QC + L + + + A LT+P E+ + ++
Sbjct: 1 MDLHIWPGSSGIDSFDSDCLVIITYLRLGKCPINLFSS-PPQKSDMNSIPLLVHGSNEVTTVHKIIEYLRKENYGLEYELSDEELARLDSLVTSLERRITPAFRWLLWADTNVYNSYTSLLYRSKLPYFYGLWLLRCWRKRIIENTEFSQLSLCSKSNSKNRYKEVESSLFEGARRCLTALSYVLGKKPFFFGERPSAIDAYVFGRLWPLLNYDRLCRKQNSNIHRLISHVYQCENLFLLCRRVQRLCFPSGADSFLTSPASDLREVQATDK 271
BLAST of Metaxin 1 vs. TrEMBL
Match: A0A0R3WJH1 (Uncharacterized protein OS=Hydatigena taeniaeformis OX=6205 GN=TTAC_LOCUS820 PE=4 SV=1) HSP 1 Score: 156.377 bits (394), Expect = 8.336e-41 Identity = 83/247 (33.60%), Postives = 133/247 (53.85%), Query Frame = 2
Query: 107 MNLYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPFLQHSLNSSVGLKHIIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDG--------LIVHVKQCNKIMELLVSIHQ 823
M+LYVWP +ES D + L VITY+++ +N+ + +++P L H N+ + II Y RKENYG+EY L+DE+LA+L L +++ + + PA +L+W S+ Y S T + + + + L++ + K S+L T AK V+ LY A RCLT+L YIL +K+FF +KP+ +DA ++G LWP+L+ D LI H+ QC ++ L + +
Sbjct: 1 MDLYVWPCSEGIESFDSDCLVVITYLRLGGCLINLNSCRDCDKSDFHNIPLLVHGSNTVTTVSKIINYLRKENYGLEYELSDEELARLESLVTSVERRVTPACRWLIWADSNVYRSYTSAFYRSNLSYLQGLWYPRRWRDKLVEAAEFSQLALCTNRDAKGRRRNVEMTLYEGAIRCLTALSYILGDKQFFFGDKPSAIDAYVFGRLWPLLNYDRLCRQQESKICHRLISHIYQCENLLNLCGRVQR 247
BLAST of Metaxin 1 vs. Ensembl Cavefish
Match: mtx1b (metaxin-1-like [Source:NCBI gene;Acc:103026555]) HSP 1 Score: 117.472 bits (293), Expect = 7.468e-30 Identity = 80/305 (26.23%), Postives = 132/305 (43.28%), Query Frame = 2
Query: 107 MNLYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPFLQHSLNSSVGL-KHIIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSYYHHRALTNPNRAPNEIVSANENTLRGKVRVFLTENWIQIRNSSIFVLFVSTMMICYAKSTKVV 1018
M LY W L S+D + L V+ Y K A AP+ + PW P+ LP L+ S II RK+ Y +Y+L+ ++ A S + + L+PA+ Y W + NY TR +AE + FP++ N M + ++ R + +L +E +DAL C+T L L +FF + P+ +DA ++G+L PIL + + L H+ + + +I Y+ + P R + + R RN + VLF M+ YA + ++
Sbjct: 5 MELYCWRGDHGLPSVDVDCLTVLAYAKFAGAPLKVHKITNPWRSPTGILPALKTREEGSFSQPSKIIIQLRKQKYNADYDLSAKEGADTLAFVSLLEEKLLPALIYTQWVDAKNYVDATRRWYAENIPFPLNFLLPNRMHGRQLERLRLVRGDPALEPGEQLEKELYQDAL-----ECMTLLSQRLGSHKFFFGDSPSSLDAYVFGHLAPILKIKLPNNKLQQHINSLENLRQFCNNILVLYFPSESRELPTRKVSPQAEGGDFDNEPHKR----------RNQILSVLFAVGAMLGYAVLSGII 294
BLAST of Metaxin 1 vs. Ensembl Cavefish
Match: mtx1a (metaxin-1-like [Source:NCBI gene;Acc:103044318]) HSP 1 Score: 114.005 bits (284), Expect = 1.266e-28 Identity = 82/303 (27.06%), Postives = 135/303 (44.55%), Query Frame = 2
Query: 113 LYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPFLQHSLNSSVGLKH-IIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSYYHHRALTNPNRAPNEIVSANENTLRGKVRVFLTENWIQIRNSSIFVLFVSTMMICYAKSTKVV 1018
L+ W L S+DP+SL V+ Y + A AP+ I PW P+ LP L+ S + II RK+ Y +Y+L+ ++ A S + + L+PA+ Y +W NY VTR A+ + FP++ F + M+ + R+ N+A E + L + A C+ L L +FF + P+ +DA ++G+L P+L + L H+K + +I Y+ PN + + +T G F E + + R + VL M+ YA T +V
Sbjct: 7 LFCWKGGWGLPSVDPDSLIVLAYARFAGAPLKIHKISNPWRSPTGCLPALKTKDEGSFSQPNKIIIQLRKQKYNADYDLSAKEGADTLAFISLLQEMLMPALIYTLWVDPKNYVEVTRRWHADNISFPLNFFLPSRMQRQQL-----ERVQLMRGNRALEAGEEAEKELNHDALECMNLLSQRLGSNKFFFGDSPSSLDAYVFGHLAPLLKIKLPSSSLQQHLKSLENLDSFCCNILSLYF-------PNESREGVGRPVSSTPEGS--EFDNEPY-KRRKQLLSVLVAVAAMLSYALLTGIV 294
BLAST of Metaxin 1 vs. Ensembl Cavefish
Match: mtx1a (metaxin-1-like [Source:NCBI gene;Acc:103044318]) HSP 1 Score: 113.62 bits (283), Expect = 3.445e-28 Identity = 82/304 (26.97%), Postives = 135/304 (44.41%), Query Frame = 2
Query: 110 NLYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPFLQHSLNSSVGLKH-IIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSYYHHRALTNPNRAPNEIVSANENTLRGKVRVFLTENWIQIRNSSIFVLFVSTMMICYAKSTKVV 1018
L+ W L S+DP+SL V+ Y + A AP+ I PW P+ LP L+ S + II RK+ Y +Y+L+ ++ A S + + L+PA+ Y +W NY VTR A+ + FP++ F + M+ + R+ N+A E + L + A C+ L L +FF + P+ +DA ++G+L P+L + L H+K + +I Y+ PN + + +T G F E + + R + VL M+ YA T +V
Sbjct: 46 ELFCWKGGWGLPSVDPDSLIVLAYARFAGAPLKIHKISNPWRSPTGCLPALKTKDEGSFSQPNKIIIQLRKQKYNADYDLSAKEGADTLAFISLLQEMLMPALIYTLWVDPKNYVEVTRRWHADNISFPLNFFLPSRMQRQQL-----ERVQLMRGNRALEAGEEAEKELNHDALECMNLLSQRLGSNKFFFGDSPSSLDAYVFGHLAPLLKIKLPSSSLQQHLKSLENLDSFCCNILSLYF-------PNESREGVGRPVSSTPEGS--EFDNEPY-KRRKQLLSVLVAVAAMLSYALLTGIV 334
BLAST of Metaxin 1 vs. Ensembl Cavefish
Match: mtx3 (metaxin 3 [Source:NCBI gene;Acc:103040731]) HSP 1 Score: 97.4413 bits (241), Expect = 1.090e-22 Identity = 75/261 (28.74%), Postives = 119/261 (45.59%), Query Frame = 2
Query: 107 MNLYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPFLQHSLNSSVGLKHIIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSYYHHRALTNPNRAPNEIVSAN 889
M L W L S+ ESL V+ Y K A A + + W + S+P L +S+ I+ RK + +Y L+ + A + + + L PA+ + W + NY ++TR FA FP++ F S A S+IL L +TE V+ +Y+ AK CL L + L +F N PT +DA ++GYL P+ L H+KQ + + + SI ++Y+ A + + A + V AN
Sbjct: 5 MELLCWGGDWDLPSVHTESLIVLAYAKFAGASLTVKPVDWTWRTITASIPQLYCEGSSATEPAQILNLLRKNRFNADYELSAKQGADTMAYIALLEEKLRPALLHTFWVDAENYANLTRPWFASHSPFPLNFFVPARQASLALSRIL---LTKAEAPLHSITE--VEGKIYSEAKECLNLLSHRLGISHYFFGNMPTSLDAFVFGYLAPLHKASLPSGQLQQHLKQLHNLCQFCSSILKNYF-TEAGSGSSPASQDAVDAN 259
BLAST of Metaxin 1 vs. Ensembl Cavefish
Match: mtx1a (metaxin-1-like [Source:NCBI gene;Acc:103044318]) HSP 1 Score: 80.4925 bits (197), Expect = 8.234e-17 Identity = 61/240 (25.42%), Postives = 105/240 (43.75%), Query Frame = 2
Query: 299 IIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSYYHHRALTNPNRAPNEIVSANENTLRGKVRVFLTENWIQIRNSSIFVLFVSTMMICYAKSTKVV 1018
II RK+ Y +Y+L+ ++ A S + + L+PA+ Y +W NY VTR A+ + FP++ F + M+ + R+ N+A E + L + A C+ L L +FF + P+ +DA ++G+L P+L + L H+K + +I Y+ PN + + +T G F E + + R + VL M+ YA T +V
Sbjct: 42 IIIQLRKQKYNADYDLSAKEGADTLAFISLLQEMLMPALIYTLWVDPKNYVEVTRRWHADNISFPLNFFLPSRMQRQQL-----ERVQLMRGNRALEAGEEAEKELNHDALECMNLLSQRLGSNKFFFGDSPSSLDAYVFGHLAPLLKIKLPSSSLQQHLKSLENLDSFCCNILSLYF-------PNESREGVGRPVSSTPEGS--EFDNEPYKR-RKQLLSVLVAVAAMLSYALLTGIV 266
BLAST of Metaxin 1 vs. Ensembl Sea Lamprey
Match: mtx3 (metaxin 3 [Source:NCBI gene;Acc:402916]) HSP 1 Score: 93.2041 bits (230), Expect = 8.803e-22 Identity = 66/249 (26.51%), Postives = 108/249 (43.37%), Query Frame = 2
Query: 107 MNLYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPFLQHSLNSSVGLKHIIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSYYHHRALTN 853
M L W L S+D L V+ Y + APV + P + LP L+ + +I+ FRKE Y +Y+L+ + A + I + L PA+ + W NY VTR +A + FP N++ +S+ +RL ++ ++ +Y AK CL L + L EK FF P+ +DAV++G+L P+L L +H+K + + + +A N
Sbjct: 6 MELLCWRGDWGLPSVDSGCLIVMAYAHFSNAPVKLKKTGNPRESLTGCLPILKSGEKTISKPLNILNCFRKEQYNADYDLSPKQGADTMAFVALIEEKLFPALLHTFWVDDQNYTGVTRPWYASTMPFPF-----NMLAPYRSSRQALTRLKLSVGRPPYMSLAEMEAQIYWDAKECLNLLSFQLGEKAFFFGEMPSSLDAVVFGHLAPLLKAPLLTKKLQLHLKAIENLCAFCERVLMRCFPGQAPVN 249
BLAST of Metaxin 1 vs. Ensembl Sea Lamprey
Match: mtx2 (metaxin 2 [Source:ZFIN;Acc:ZDB-GENE-021210-2]) HSP 1 Score: 56.6102 bits (135), Expect = 1.592e-9 Identity = 46/228 (20.18%), Postives = 102/228 (44.74%), Query Frame = 2
Query: 164 LAVITYVKIAQAPVNIFTNIRPWS---CPSYSLPFLQHSLNSSVGLKHIIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSYYHH 838
LAV ++++ PV + RP + PS +PF+ + L I+ + + + + + +L ++ A++ ++ L+ A Y++W + ++R + +P++ + A K R + ++ A T E V D + +CL +L L + +F +PT +DA+++G+L+ +L + D L V+ + +L + + Y+
Sbjct: 41 LAVQAFLRMCSLPVYVV--YRPNAEQMSPSGKVPFIHVGNHVVSELGPIVQFVKAKGHCLSSSLDEQQKAEMKAYMELVNNVLLTAELYILWCDDTTCKEISRPRYGSPYPWPLN-------RLLAYQKQWEVRRKMKALSWASKTPEQVHDEV----NQCLRALSLRLGSQSYFFGRQPTELDALVFGHLFTLLTTELSSDTLPELVRAYPNLADLCQRVERQYFRE 255
BLAST of Metaxin 1 vs. Ensembl Nematostella
Match: EDO33160 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7ST15]) HSP 1 Score: 100.523 bits (249), Expect = 4.147e-24 Identity = 58/209 (27.75%), Postives = 103/209 (49.28%), Query Frame = 2
Query: 101 NFMNLYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPFLQHSLNSSVGLKHIIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYL 727
+ + L+ WP L S+D LAV++YVK A P+ + + + W P++ P ++ I+ + R++N+ +Y LT + A + I L+PA+ Y +W S NY TR ++A + P++ F + A K L R+ + + + +++ L+ A CLT L +L +K+FF PT +DAV + +L
Sbjct: 3 DVLELFSWPGDFGLPSVDIPCLAVLSYVKFAGCPLKVNRSNKFWKSPTWEFPVMKSGEEVLTSPYKIMDHLRQKNFNADYQLTAKQGADTLAFIALIEDKLLPAMHYTLWVDSKNYVEFTRPMYARKLPLPLNFFVPGRI---ANQKKL--RIGHKLDPEEEEANGELENMLFKEAIECLTHLSVLLGDKDFFFGESPTTLDAVAFAHL 206
BLAST of Metaxin 1 vs. Ensembl Nematostella
Match: EDO34336 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SPN8]) HSP 1 Score: 49.2914 bits (116), Expect = 7.187e-7 Identity = 49/225 (21.78%), Postives = 98/225 (43.56%), Query Frame = 2
Query: 167 AVITYVKIAQAPVNI--FTNIRPWSCPSYSLPFLQHSLNSSVGLKHIIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSL-FWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSYY 832
++I ++K Q P ++ N S P+ +P L+ + G + I + V + D A++ S I++ ++P Y++W T ++ FP+ L + + K A + L + LN+Q +A + EEF ++ +L L ++FI +PT VDA+ +G++ IL D L+ V + + + ++ I ++
Sbjct: 31 SLIAFLKFCQLPYDLKCVKNAESMS-PTGEVPLLRAGKDLVGGPQDIFSLVNHKGLSVSQDFEARDKAEMKAYISLINRSILPTELYMLWCKPGWQIRTTHQYGSQ---FPVPLNYILSYRKQWAAHRSLHA-LNWQRKKEAGVVEEF---------EKACQALAEKLGTNQYFIQGRPTEVDALAFGHINSILSRYQPDDTLVAIVHKHRNLEDFVMRILNDFF 241
BLAST of Metaxin 1 vs. Ensembl Nematostella
Match: EDO43101 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZI7]) HSP 1 Score: 48.521 bits (114), Expect = 1.067e-6 Identity = 47/209 (22.49%), Postives = 88/209 (42.11%), Query Frame = 2
Query: 113 LYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPFLQHSLNSSVGLKHIIPYFRKE-NYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNK---AKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYL 727
L+ PP + P SL + TY+++ + P F + S +PF+++ + I Y K+ N + +L+ E A H + + ++ ++ Y W NY + ++SNL K L +L+ K A + K+ +Y A+ L ++ +L EKEFF+ ++P +D ++G L
Sbjct: 3 LHQHPPGPTIPGFLPNSLKLETYLRMVKIPYENFYESKLGSSKE-KVPFIEYQGDKVQDTNFCIKYLNKKFNVDPDAHLSAEQKAMCHAIQAMAEENTYWSLAYYRW--VDNYQETKK-------------YYSNLA---PVYKDLRPKLDQNKCIKCMQAHGIGKHTKEEIYAIAEEDLRAMSALLGEKEFFMDSEPCTLDCTMFGLL 192
BLAST of Metaxin 1 vs. Ensembl Nematostella
Match: EDO27861 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T835]) HSP 1 Score: 46.9802 bits (110), Expect = 4.264e-6 Identity = 21/69 (30.43%), Postives = 37/69 (53.62%), Query Frame = 2
Query: 299 IIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLF 505
I+ + R++N+ +Y LT + A + I L+PA+ Y +W S NY TR ++A + P++ F
Sbjct: 19 IMDHLRQKNFNADYQLTAKQGADTLAFIALIEDKLLPAMHYTLWVDSKNYVEFTRPMYARKLPLPLNFF 87
BLAST of Metaxin 1 vs. Ensembl Medaka
Match: mtx1a (metaxin-1 [Source:NCBI gene;Acc:101163689]) HSP 1 Score: 114.39 bits (285), Expect = 8.513e-29 Identity = 73/242 (30.17%), Postives = 116/242 (47.93%), Query Frame = 2
Query: 110 NLYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPFLQHSLNSSVG-LKHIIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSYY 832
L+ W L S+ + L V+ Y + A AP+ + PW PS SLP + S ++ II + RK+ + +Y+L+ ++ A S + + L PA+ Y W NY VTR FAE + FP++ F M+S+ K+ RL Q + + EE K+ LY A CL L L ++FF + P+ +DA ++G+L PIL L H+K + + +I Y+
Sbjct: 6 ELFCWEGDWGLPSVSTDCLVVLAYAQFAGAPLKVRKICNPWRSPSGSLPAFRTSQKETLSRTSDIIIHLRKQKFNADYDLSAKEGADSLAFISLMDEKLKPALIYTFWIEPKNYVDVTRRWFAEHMPFPLNFFLPGRMQSQQLEKL---RL-LQGDERLEAGEELEKE-LYRDATECLNLLSQRLGSQKFFFGDSPSSLDAYVFGHLAPILRCKLPNGKLQQHLKSLDNLANFCSNILLLYF 242
BLAST of Metaxin 1 vs. Ensembl Medaka
Match: mtx3 (metaxin 3 [Source:NCBI gene;Acc:101155695]) HSP 1 Score: 78.1814 bits (191), Expect = 6.914e-16 Identity = 50/180 (27.78%), Postives = 84/180 (46.67%), Query Frame = 2
Query: 296 HIIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQ-------CNKIMELLVS 814
I+ + RK+ + +Y LT A + + + L PA+ + W + NY S+TR FA FP++ + + A S+IL L +++E ++ +Y+ AK CL L Y L F N PT +DA ++G++ P+ L H+KQ C+ I+E+ S
Sbjct: 60 QILSFMRKQRFNADYELTARQGADTMAYIALLEEKLRPALLHTFWVDTENYTSLTRPWFASRSPFPLNFIVPSRLARMALSRIL---LTKGEAPLHRISE--IEGKIYSDAKECLNLLSYRLGTANHFFGNSPTSLDAFVFGFVAPLHRASLPSSHLQSHLKQLENLTHFCDNILEVYFS 234
BLAST of Metaxin 1 vs. Ensembl Medaka
Match: mtx3 (metaxin 3 [Source:NCBI gene;Acc:101155695]) HSP 1 Score: 76.6406 bits (187), Expect = 8.809e-16 Identity = 51/181 (28.18%), Postives = 83/181 (45.86%), Query Frame = 2
Query: 296 HIIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKD-ALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQ-------CNKIMELLVS 814
I+ + RK+ + +Y LT A + + + L PA+ + W + NY S+TR FA FP++ + + A S+IL T + L+ V+ +Y+ AK CL L Y L F N PT +DA ++G++ P+ L H+KQ C+ I+E+ S
Sbjct: 7 QILSFMRKQRFNADYELTARQGADTMAYIALLEEKLRPALLHTFWVDTENYTSLTRPWFASRSPFPLNFIVPSRLARMALSRIL------LTKGECGLSTLPVRHLRIYSDAKECLNLLSYRLGTANHFFGNSPTSLDAFVFGFVAPLHRASLPSSHLQSHLKQLENLTHFCDNILEVYFS 181
BLAST of Metaxin 1 vs. Ensembl Medaka
Match: mtx2 (metaxin 2 [Source:NCBI gene;Acc:101167474]) HSP 1 Score: 61.2326 bits (147), Expect = 2.207e-10 Identity = 51/231 (22.08%), Postives = 103/231 (44.59%), Query Frame = 2
Query: 161 SLAVITYVKIAQAPVNIFTNIRP---WSCPSYSLPFLQHSLNSSVG-LKHIIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSYYHHR 841
SLAV TY+++ PV + RP + PS +PF+ H N V L I+ + + + + + L D A++ ++ L+ A ++ W + + +TR + +P++L + + + K+ + +TV D +Y +C +L L + +F PT +DA+++G+L+ IL L+ V+ + ++ I Q+Y+ +
Sbjct: 41 SLAVQTYLRMCGLPVQVV--CRPNAEYMSPSGKIPFI-HVGNQVVSELGPIVQFSKAKGHSLSDGLDDVQRAEMKAYMELVNNMLLTAELFIQWCDETTVSQITRHRYGTPYSWPLNLILAYQKQWEVRRKMNAVGWGGKTV-----------DQVYEDVSQCCQALSQRLGTQPYFF-KIPTELDALVFGHLFTILTTQLTNTELLERVRSYSNLLSFCRRIEQTYFESK 256
BLAST of Metaxin 1 vs. Ensembl Medaka
Match: mtx2 (metaxin 2 [Source:NCBI gene;Acc:101167474]) HSP 1 Score: 55.4546 bits (132), Expect = 1.797e-8 Identity = 47/226 (20.80%), Postives = 99/226 (43.81%), Query Frame = 2
Query: 176 TYVKIAQAPVNIFTNIRP---WSCPSYSLPFLQHSLNSSVG-LKHIIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSYYHHR 841
TY+++ PV + RP + PS +PF+ H N V L I+ + + + + + L D A++ ++ L+ A ++ W + + +TR + +P++L + + + K+ + +TV D +Y +C +L L + +F PT +DA+++G+L+ IL L+ V+ + ++ I Q+Y+ +
Sbjct: 47 TYLRMCGLPVQVV--CRPNAEYMSPSGKIPFI-HVGNQVVSELGPIVQFSKAKGHSLSDGLDDVQRAEMKAYMELVNNMLLTAELFIQWCDETTVSQITRHRYGTPYSWPLNLILAYQKQWEVRRKMNAVGWGGKTV-----------DQVYEDVSQCCQALSQRLGTQPYFF-KIPTELDALVFGHLFTILTTQLTNTELLERVRSYSNLLSFCRRIEQTYFESK 257
BLAST of Metaxin 1 vs. Planmine SMEST
Match: SMESG000013267.1 (SMESG000013267.1) HSP 1 Score: 629.402 bits (1622), Expect = 0.000e+0 Identity = 305/305 (100.00%), Postives = 305/305 (100.00%), Query Frame = 2
Query: 107 MNLYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPFLQHSLNSSVGLKHIIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSYYHHRALTNPNRAPNEIVSANENTLRGKVRVFLTENWIQIRNSSIFVLFVSTMMICYAKSTKVVK 1021
MNLYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPFLQHSLNSSVGLKHIIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSYYHHRALTNPNRAPNEIVSANENTLRGKVRVFLTENWIQIRNSSIFVLFVSTMMICYAKSTKVVK
Sbjct: 1 MNLYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPFLQHSLNSSVGLKHIIPYFRKENYGVEYNLTDEDLAKLHVLSSNIHQDLIPAVDYLMWYHSSNYNSVTRSLFAEAVGFPMSLFWSNLMKSKATSKILSSRLNFQTVNKAKLTEEFVKDALYNTAKRCLTSLEYILNEKEFFISNKPTYVDAVLYGYLWPILHLDYELDGLIVHVKQCNKIMELLVSIHQSYYHHRALTNPNRAPNEIVSANENTLRGKVRVFLTENWIQIRNSSIFVLFVSTMMICYAKSTKVVK 305 The following BLAST results are available for this feature:
BLAST of Metaxin 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Metaxin 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 3
BLAST of Metaxin 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 2
BLAST of Metaxin 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Metaxin 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 2
BLAST of Metaxin 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Metaxin 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Metaxin 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Metaxin 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Metaxin 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 2
BLAST of Metaxin 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Metaxin 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 4
BLAST of Metaxin 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Metaxin 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 1
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30021481 ID=SMED30021481|Name=Metaxin 1|organism=Schmidtea mediterranea sexual|type=transcript|length=1087bpback to top protein sequence of SMED30021481-orf-1 >SMED30021481-orf-1 ID=SMED30021481-orf-1|Name=SMED30021481-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=306bp MNLYVWPPLGALESIDPESLAVITYVKIAQAPVNIFTNIRPWSCPSYSLPback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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