SMED30021475
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30021475 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 3
Alignments
SMED30021475 aligns in the following genomic locations:
Homology
BLAST of SMED30021475 vs. Ensembl Human
Match: HSD17B12 (hydroxysteroid 17-beta dehydrogenase 12 [Source:HGNC Symbol;Acc:HGNC:18646]) HSP 1 Score: 173.711 bits (439), Expect = 3.017e-51 Identity = 84/231 (36.36%), Postives = 139/231 (60.17%), Query Frame = -3 Query: 164 GNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHS 856 G W VVTG+TDGIGK + E+LAK ++LISR+++KL S E+ EKF++ + I DF IYD I + GL +G+L+NNVG +Y P+++ D M++ N LS MT+++L + + G I+N+SS S L +P+LT+Y++ K+ ++ F+ CL E ++G +FVQ+ P++V +KL+ I+ P+ E F S ++ + ++ GY+ H+ Sbjct: 50 GEWAVVTGSTDGIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKVETRTIAVDFASEDIYDKIKTGLAGLEIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKMTQLVLPGMVERSKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKG----VFVQSVLPYFVATKLAKIRKPTLDKPSPETFVKSAIKTVGLQSRTNGYLIHA 276
BLAST of SMED30021475 vs. Ensembl Human
Match: HSDL1 (hydroxysteroid dehydrogenase like 1 [Source:HGNC Symbol;Acc:HGNC:16475]) HSP 1 Score: 163.31 bits (412), Expect = 4.894e-47 Identity = 89/263 (33.84%), Postives = 152/263 (57.79%), Query Frame = -3 Query: 122 PVSESKFDKIKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTK-IYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSG----IKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFL 895 P S+ D IK YG W VV+G TDGIGK + E+LA R N+ILISRNEEKL + ++++ + +++ I ADF + IY I E+++ VG+L+NNVG YP P ++T LS+ D+++ N + LM ++L + ++ G I+ +SS S P L +++ K+ L+ F+ LQ E ++G IFVQ+ PF+V + ++ + +LVP+ + + + L + ++ GY +HS + + + +P++L Sbjct: 54 PRLGSRADLIKQYGRWAVVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKDKDVGILVNNVGVFYPYPQYFT--QLSEDKLWDIINVNIAAASLMVHVVLPGMVERKKGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKG----IFVQSLIPFYVATSMTAPSNFLHRCSWLVPSPKVYAHHAVSTLGISKRTTGYWSHSIQ-FLFAQYMPEWL 309
BLAST of SMED30021475 vs. Ensembl Human
Match: HSD17B3 (hydroxysteroid 17-beta dehydrogenase 3 [Source:HGNC Symbol;Acc:HGNC:5212]) HSP 1 Score: 152.91 bits (385), Expect = 2.841e-43 Identity = 89/249 (35.74%), Postives = 138/249 (55.42%), Query Frame = -3 Query: 125 IKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFID-MLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKF 868 ++S G W V+TG DGIGK + +LAKR N++LISR EKL + E+ SVK I ADF K IY+HI E + GL +G+L+NNVG P+ + L+ D I ++HCN S V MT+++LK +Q G+I+N+SS + P+ +MY++ K+ + F+ LQ E A+ + +Q TP+ V + ++ + TA+EF L + ++ G + H FL+ LIP + Sbjct: 44 LRSMGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADFTKDDIYEHIKEKLAGLEIGILVNNVGML---PNLLPSHFLNAPDEIQSLIHCNITSVVKMTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAK----EVIIQVLTPYAVSTAMTKYLNTNVITKTADEFVKESLNYVTIGGETCGCLAHEILAGFLS-LIPAW 284
BLAST of SMED30021475 vs. Ensembl Human
Match: HSD17B3 (hydroxysteroid 17-beta dehydrogenase 3 [Source:HGNC Symbol;Acc:HGNC:5212]) HSP 1 Score: 149.828 bits (377), Expect = 2.692e-42 Identity = 84/235 (35.74%), Postives = 131/235 (55.74%), Query Frame = -3 Query: 167 IKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFID-MLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITH 868 ++S G W V+TG DGIGK + +LAKR N++LISR EKL + E+ SVK I ADF K IY+HI E + GL +G+L+NNVG P+ + L+ D I ++HCN S V MT+++LK +Q G+I+N+SS + P+ +MY++ K+ + F+ LQ E A+ + +Q TP+ V + ++ + TA+EF L + ++ G + H Sbjct: 44 LRSMGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADFTKDDIYEHIKEKLAGLEIGILVNNVGML---PNLLPSHFLNAPDEIQSLIHCNITSVVKMTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAK----EVIIQVLTPYAVSTAMTKYLNTNVITKTADEFVKESLNYVTIGGETCGCLAH 271
BLAST of SMED30021475 vs. Ensembl Human
Match: HSD17B3 (hydroxysteroid 17-beta dehydrogenase 3 [Source:HGNC Symbol;Acc:HGNC:5212]) HSP 1 Score: 137.502 bits (345), Expect = 6.754e-38 Identity = 75/194 (38.66%), Postives = 112/194 (57.73%), Query Frame = -3 Query: 290 IKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFID-MLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFW 868 ++S G W V+TG DGIGK + +LAKR N++LISR EKL + E+ SVK I ADF K IY+HI E + GL +G+L+NNVG P+ + L+ D I ++HCN S V MT+++LK +Q G+I+N+SS + P+ +MY++ K+ + F+ LQ E A+ + + P W Sbjct: 44 LRSMGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADFTKDDIYEHIKEKLAGLEIGILVNNVGML---PNLLPSHFLNAPDEIQSLIHCNITSVVKMTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVIIQAGFLSLIPAW 234
BLAST of SMED30021475 vs. Ensembl Celegans
Match: stdh-1 (Putative steroid dehydrogenase 1 [Source:UniProtKB/Swiss-Prot;Acc:Q17703]) HSP 1 Score: 142.124 bits (357), Expect = 1.588e-39 Identity = 83/275 (30.18%), Postives = 142/275 (51.64%), Query Frame = -3 Query: 56 KIKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFR-ISVKYITADFRKTKI--YDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFLNKVLVRRSMMKLRDQASRKRDK 871 K K+ +W VVTG TDGIGK + +LAKR FN+ ++SR + KL +E++E I V++ T DF + Y+ + + + +G+LINNVG + P+ + ++ N L L++ +L + ++ G+I+N+ S + + ++Y++ K + T CLQ E QG I Q TP V +K++G F P ++ F S L + Q+ GYITH E L KL+P F+ ++++ +LR+ ++ +K Sbjct: 42 KKKAGASWAVVTGATDGIGKSYSFELAKRGFNVYIVSRTQSKLEHTKKEILEVHPDIEVRFATFDFTNPSVSDYEKLLSKLNEVSIGILINNVGMFFDYPEMLHKINGGIDSIANVTIINTLPATLLSAGILPQMVPRKAGIIVNIGSVAGLATMAEWSVYSATKKYVEWITGCLQKEYGHQG----IIFQAITPAMVATKMAGNPNTSFFTPDSDTFAKSALNTIGHASQTTGYITHQIECEML-KLLPDFVIDRSIKQTSAQLREALAKNENK 311
BLAST of SMED30021475 vs. Ensembl Celegans
Match: let-767 (Very-long-chain 3-oxooacyl-coA reductase let-767 [Source:UniProtKB/Swiss-Prot;Acc:Q09517]) HSP 1 Score: 141.739 bits (356), Expect = 2.584e-39 Identity = 84/276 (30.43%), Postives = 145/276 (52.54%), Query Frame = -3 Query: 56 KIKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKF-RISVKYITADFRKT--KIYDHIAESVEGLPVGLLINNVGAAYPSPD-FYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFLNKVLVRRSMMKLRDQASRKRDK 871 K ++ +W VVTG TDGIGK + +LA+R FN++L+SR + KL +E++EK+ I V+ DF Y + ++ + +G+LINNVG +Y PD + D +R ++ N L L++ +L + ++ GVI+N+ S++ ++ + +Y++ K ++ T L+ E + QG I VQ P V +K+S +K F P F S L + + GYITH + ++ LIP F+ ++ + R A RK+++ Sbjct: 42 KKRAGASWAVVTGATDGIGKAYAFELARRGFNVLLVSRTQSKLDETKKEILEKYSSIEVRTAAFDFTNAAPSAYKDLLATLNQVEIGVLINNVGMSYEYPDVLHKVDGGIER-LANITTINTLPPTLLSAGILPQMVARKAGVIVNVGSSAGANQMALWAVYSATKKYVSWLTAILRKEYEHQG----ITVQTIAPMMVATKMSKVKRTSFFTPDGAVFAKSALNTVGNTSDTTGYITHQLQLELMD-LIPTFIRDKILTNMSVGTRAAALRKKER 311
BLAST of SMED30021475 vs. Ensembl Celegans
Match: let-767 (Very-long-chain 3-oxooacyl-coA reductase let-767 [Source:UniProtKB/Swiss-Prot;Acc:Q09517]) HSP 1 Score: 141.739 bits (356), Expect = 2.584e-39 Identity = 84/276 (30.43%), Postives = 145/276 (52.54%), Query Frame = -3 Query: 56 KIKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKF-RISVKYITADFRKT--KIYDHIAESVEGLPVGLLINNVGAAYPSPD-FYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFLNKVLVRRSMMKLRDQASRKRDK 871 K ++ +W VVTG TDGIGK + +LA+R FN++L+SR + KL +E++EK+ I V+ DF Y + ++ + +G+LINNVG +Y PD + D +R ++ N L L++ +L + ++ GVI+N+ S++ ++ + +Y++ K ++ T L+ E + QG I VQ P V +K+S +K F P F S L + + GYITH + ++ LIP F+ ++ + R A RK+++ Sbjct: 42 KKRAGASWAVVTGATDGIGKAYAFELARRGFNVLLVSRTQSKLDETKKEILEKYSSIEVRTAAFDFTNAAPSAYKDLLATLNQVEIGVLINNVGMSYEYPDVLHKVDGGIER-LANITTINTLPPTLLSAGILPQMVARKAGVIVNVGSSAGANQMALWAVYSATKKYVSWLTAILRKEYEHQG----ITVQTIAPMMVATKMSKVKRTSFFTPDGAVFAKSALNTVGNTSDTTGYITHQLQLELMD-LIPTFIRDKILTNMSVGTRAAALRKKER 311
BLAST of SMED30021475 vs. Ensembl Celegans
Match: let-767 (Very-long-chain 3-oxooacyl-coA reductase let-767 [Source:UniProtKB/Swiss-Prot;Acc:Q09517]) HSP 1 Score: 141.354 bits (355), Expect = 4.568e-39 Identity = 84/276 (30.43%), Postives = 145/276 (52.54%), Query Frame = -3 Query: 56 KIKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKF-RISVKYITADFRKT--KIYDHIAESVEGLPVGLLINNVGAAYPSPD-FYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFLNKVLVRRSMMKLRDQASRKRDK 871 K ++ +W VVTG TDGIGK + +LA+R FN++L+SR + KL +E++EK+ I V+ DF Y + ++ + +G+LINNVG +Y PD + D +R ++ N L L++ +L + ++ GVI+N+ S++ ++ + +Y++ K ++ T L+ E + QG I VQ P V +K+S +K F P F S L + + GYITH + ++ LIP F+ ++ + R A RK+++ Sbjct: 59 KKRAGASWAVVTGATDGIGKAYAFELARRGFNVLLVSRTQSKLDETKKEILEKYSSIEVRTAAFDFTNAAPSAYKDLLATLNQVEIGVLINNVGMSYEYPDVLHKVDGGIER-LANITTINTLPPTLLSAGILPQMVARKAGVIVNVGSSAGANQMALWAVYSATKKYVSWLTAILRKEYEHQG----ITVQTIAPMMVATKMSKVKRTSFFTPDGAVFAKSALNTVGNTSDTTGYITHQLQLELMD-LIPTFIRDKILTNMSVGTRAAALRKKER 328
BLAST of SMED30021475 vs. Ensembl Celegans
Match: stdh-3 (Putative steroid dehydrogenase 3 [Source:UniProtKB/Swiss-Prot;Acc:Q17704]) HSP 1 Score: 135.961 bits (341), Expect = 3.001e-37 Identity = 83/274 (30.29%), Postives = 141/274 (51.46%), Query Frame = -3 Query: 59 KIKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKF-RISVKYITADFRKTKIYDH--IAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFLNKVLVRRSMMKLRDQASRKRD 871 K K+ +W V+TG TDGIGK F +LAKR FN+ ++SR + KL +E+MEK+ + V++ T DF I D+ + + + +G+LINNVG + P+ ++ N L L++ +L + ++ G+I+N+ S + ++ ++Y++ K + T CL+ E + QG I +Q TP V +KLSG P + F S L + Q+ GYI H + L L P+ V++S ++ R++A K++ Sbjct: 42 KKKAGASWAVITGGTDGIGKSFSFELAKRGFNIYIVSRTQSKLEQTKKEIMEKYSNVEVRFATFDFTNPSISDYKKLLSQLNEVSIGMLINNVGMLFEYPENLHKTVGGIDVVANVTILNTLPVTLLSAGILPQMVSRKTGIIVNIGSVAGAAKMAEWSVYSASKKYVEWLTGCLRKEYEHQG----IIIQAITPALVATKLSGHTETSLFCPDSATFAKSALNTVGHTSQTTGYINHQIQCEML-ALFPECFLDSFVKKSSVETREKALAKKE 310
BLAST of SMED30021475 vs. Ensembl Fly
Match: spidey (gene:FBgn0029975 transcript:FBtr0071091) HSP 1 Score: 164.851 bits (416), Expect = 5.352e-48 Identity = 91/272 (33.46%), Postives = 155/272 (56.99%), Query Frame = -3 Query: 56 GNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKT-KIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFI-DMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENW---FLNKLIPKFLNKVLVRRSMMKLRDQASRKRDK 856 G W VVTG+TDGIGK + ++LA+R L+LISR+ EKL + ++E+ +K+ + V+ I DF +IYD I E GL VG+L+NNVG +Y P+++ + +D F+ +++ N S MT + L + ++ GVIIN+SS + + P+L++Y+S K+ +N F++ LQ E G I +Q+ P +V + +S I+ P+ E + S L L Q+ GY+ H+ F + + + +V ++++ R +A R+ K Sbjct: 52 GEWAVVTGSTDGIGKAYAKELARRGLKLVLISRSLEKLNVVAKEIGDKYGVEVRVIDVDFTGGDEIYDKIREKTTGLNVGVLVNNVGISYGHPEYFLDCYKADPPFLRNIVAANIHSVTHMTALFLPGMISQRRGVIINVSSTAGVIPNPLLSVYSSTKAFVNKFSDDLQTEYKEHG----ILIQSVQPGFVATNMSKIRKASVFAPSPETYVRSALSTLGIATQTAGYLPHALLQLVIHFTEAVFGEQFARNIVMKNILGTRKRALRRLAK 319
BLAST of SMED30021475 vs. Ensembl Fly
Match: CG13284 (gene:FBgn0032614 transcript:FBtr0345747) HSP 1 Score: 157.532 bits (397), Expect = 3.643e-45 Identity = 88/276 (31.88%), Postives = 153/276 (55.43%), Query Frame = -3 Query: 56 IKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTK-IYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTR----KFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFLNKVLVRRSMMKLRDQASRKRDK 868 + +G W VVTG TDGIGK + +LA++ NL+LISR +EKL+ + E+ ++++ K+I ADF K + +YD I + + G+ VG+L+NNVG Y P+ + D +S+ ++L N S ++TR +L + ++ G I+N+ S+S +P +T+YA+ K + F+ L+ E+ A I VQ P +V++K++ R P A F S + L + ++ G+ TH + + + KL P + L + +LR +A ++ K Sbjct: 52 VDKFGQWAVVTGATDGIGKEYARELARQGINLVLISRTKEKLIAVTNEIESQYKVKTKWIAADFAKGREVYDQIEKELAGIDVGILVNNVGMMYEHPE--SLDLVSEDLLWNLLTVNMGSVTMLTRKILPQMIGRRKGAIVNLGSSSELQPLPNMTVYAASKKFVTYFSKALELEV----AEHNIHVQLVMPNFVVTKMNAYTDRVMQGGLFFPNAYTFARSAVFTLGKTSETNGFWTHGIQ-YAIMKLAPLPIRTYLGHQLFKRLRIEALEQKQK 320
BLAST of SMED30021475 vs. Ensembl Fly
Match: CG13284 (gene:FBgn0032614 transcript:FBtr0080926) HSP 1 Score: 157.532 bits (397), Expect = 3.643e-45 Identity = 88/276 (31.88%), Postives = 153/276 (55.43%), Query Frame = -3 Query: 56 IKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTK-IYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTR----KFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFLNKVLVRRSMMKLRDQASRKRDK 868 + +G W VVTG TDGIGK + +LA++ NL+LISR +EKL+ + E+ ++++ K+I ADF K + +YD I + + G+ VG+L+NNVG Y P+ + D +S+ ++L N S ++TR +L + ++ G I+N+ S+S +P +T+YA+ K + F+ L+ E+ A I VQ P +V++K++ R P A F S + L + ++ G+ TH + + + KL P + L + +LR +A ++ K Sbjct: 52 VDKFGQWAVVTGATDGIGKEYARELARQGINLVLISRTKEKLIAVTNEIESQYKVKTKWIAADFAKGREVYDQIEKELAGIDVGILVNNVGMMYEHPE--SLDLVSEDLLWNLLTVNMGSVTMLTRKILPQMIGRRKGAIVNLGSSSELQPLPNMTVYAASKKFVTYFSKALELEV----AEHNIHVQLVMPNFVVTKMNAYTDRVMQGGLFFPNAYTFARSAVFTLGKTSETNGFWTHGIQ-YAIMKLAPLPIRTYLGHQLFKRLRIEALEQKQK 320
BLAST of SMED30021475 vs. Ensembl Fly
Match: CG13284 (gene:FBgn0032614 transcript:FBtr0332333) HSP 1 Score: 157.147 bits (396), Expect = 6.281e-45 Identity = 88/276 (31.88%), Postives = 153/276 (55.43%), Query Frame = -3 Query: 56 IKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTK-IYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTR----KFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFLNKVLVRRSMMKLRDQASRKRDK 868 + +G W VVTG TDGIGK + +LA++ NL+LISR +EKL+ + E+ ++++ K+I ADF K + +YD I + + G+ VG+L+NNVG Y P+ + D +S+ ++L N S ++TR +L + ++ G I+N+ S+S +P +T+YA+ K + F+ L+ E+ A I VQ P +V++K++ R P A F S + L + ++ G+ TH + + + KL P + L + +LR +A ++ K Sbjct: 65 VDKFGQWAVVTGATDGIGKEYARELARQGINLVLISRTKEKLIAVTNEIESQYKVKTKWIAADFAKGREVYDQIEKELAGIDVGILVNNVGMMYEHPE--SLDLVSEDLLWNLLTVNMGSVTMLTRKILPQMIGRRKGAIVNLGSSSELQPLPNMTVYAASKKFVTYFSKALELEV----AEHNIHVQLVMPNFVVTKMNAYTDRVMQGGLFFPNAYTFARSAVFTLGKTSETNGFWTHGIQ-YAIMKLAPLPIRTYLGHQLFKRLRIEALEQKQK 333
BLAST of SMED30021475 vs. Ensembl Fly
Match: CG13284 (gene:FBgn0032614 transcript:FBtr0332334) HSP 1 Score: 157.147 bits (396), Expect = 6.638e-45 Identity = 88/276 (31.88%), Postives = 153/276 (55.43%), Query Frame = -3 Query: 56 IKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTK-IYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTR----KFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFLNKVLVRRSMMKLRDQASRKRDK 868 + +G W VVTG TDGIGK + +LA++ NL+LISR +EKL+ + E+ ++++ K+I ADF K + +YD I + + G+ VG+L+NNVG Y P+ + D +S+ ++L N S ++TR +L + ++ G I+N+ S+S +P +T+YA+ K + F+ L+ E+ A I VQ P +V++K++ R P A F S + L + ++ G+ TH + + + KL P + L + +LR +A ++ K Sbjct: 66 VDKFGQWAVVTGATDGIGKEYARELARQGINLVLISRTKEKLIAVTNEIESQYKVKTKWIAADFAKGREVYDQIEKELAGIDVGILVNNVGMMYEHPE--SLDLVSEDLLWNLLTVNMGSVTMLTRKILPQMIGRRKGAIVNLGSSSELQPLPNMTVYAASKKFVTYFSKALELEV----AEHNIHVQLVMPNFVVTKMNAYTDRVMQGGLFFPNAYTFARSAVFTLGKTSETNGFWTHGIQ-YAIMKLAPLPIRTYLGHQLFKRLRIEALEQKQK 334
BLAST of SMED30021475 vs. Ensembl Zebrafish
Match: hsd17b12b (hydroxysteroid (17-beta) dehydrogenase 12b [Source:NCBI gene;Acc:322626]) HSP 1 Score: 182.185 bits (461), Expect = 1.163e-54 Identity = 97/253 (38.34%), Postives = 150/253 (59.29%), Query Frame = -3 Query: 116 KIKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIP-KFLNK 871 + S G W VVTG TDGIGK + E+LA+R F ++LISR +EKL S+ + K+++ K I+ADF IY I + GL +G+L+NNVG +Y P+F+ D +M++ N +S MTR++L + + GVI+N++SAS +P+LT+Y+S K+ ++ F+ L AE ++G I +Q+ PF+V +KLS I+ +PT E + + L + QS GY+ H+ W L+P K LNK Sbjct: 43 RASSLGKWAVVTGATDGIGKAYAEELARRGFAIVLISRTQEKLDEVSKAIESKYKVETKTISADFGSVDIYPKIESGLAGLEIGVLVNNVGVSYSYPEFFLNIPDVDSFINNMININIMSVCQMTRLVLPRMVDRSKGVILNVASASGMYPVPLLTLYSSTKAFVDFFSRGLDAEYKSKG----IIIQSVLPFYVTTKLSKIRKPTLDIPTPERYVKAQLSTIGLQTQSNGYLPHAIMGWVTASLLPAKLLNK 291
BLAST of SMED30021475 vs. Ensembl Zebrafish
Match: hsd17b12a (hydroxysteroid (17-beta) dehydrogenase 12a [Source:NCBI gene;Acc:327417]) HSP 1 Score: 174.481 bits (441), Expect = 1.155e-51 Identity = 90/244 (36.89%), Postives = 143/244 (58.61%), Query Frame = -3 Query: 131 GNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSD-RDFI-DMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIP 856 G W VVTG TDGIGK + E+LA+R F+++LISR++EKL ++ L +++ K I DF + +Y I + + GL +G+L+NNVG +Y P+F+ H+ D +FI M++ N S MTR++L + GVI+N+SSAS +P+LT+Y+S K+ ++ F+ LQ E +G I +Q+ PF+V +K++ I+ PT E + + L + Q+ GY H+ W L P Sbjct: 56 GKWAVVTGATDGIGKSYAEELARRGFSMMLISRSQEKLDDVAKSLESTYKVETKTIAVDFSQIDVYPKIEKGLAGLEIGILVNNVGISYSYPEFFL--HIPDLENFITTMINVNITSVCQMTRLVLPRMEARAKGVILNISSASGMFPVPLLTIYSSTKAFVDFFSRGLQTEYKCKG----IIIQSVLPFFVATKMTKIRKPTLDKPTPERYVAAELNTVGLQDQTNGYFPHAVMGWVTTILAP 293
BLAST of SMED30021475 vs. Ensembl Zebrafish
Match: hsd17b3 (hydroxysteroid (17-beta) dehydrogenase 3 [Source:ZFIN;Acc:ZDB-GENE-040426-1339]) HSP 1 Score: 166.007 bits (419), Expect = 1.750e-48 Identity = 100/283 (35.34%), Postives = 160/283 (56.54%), Query Frame = -3 Query: 56 PVSESKFDKIKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIAESVEGLPVGLLINNVG---AAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFLNKVLVRRSMMKLRDQASRKRDK 895 P+ E+ F S G W V+TG +DGIG+ + E+L+K+ ++I+ISRN+EKL ++++ VK I ADF K IY HI E++EGL +G+L+NNVG + P T+D L +R + D+++CN S V M RI+L ++ GVI+N+SS + + P+ T+YA+ K + F+ LQAE ++G I +Q PF V + ++G + + TAEEF S L+ L Q++G ITH+ L +++ VL + + + RD+ Sbjct: 37 PLPEAFF---TSLGKWAVITGGSDGIGRAYAEELSKQGMSVIIISRNQEKLDRAAKKIELNTGGKVKVIAADFTKDDIYGHITENIEGLDIGVLVNNVGILPSQIPCKLLETSD-LEERIY-DIVNCNVKSMVKMCRIVLPGMQQRRRGVILNVSSGIAKIPCPIYTLYAASKVFVERFSQGLQAEYISKG----IIIQTVAPFGVSTAMTGHQKPDMVTFTAEEFVRSSLKYLKTGDQTYGSITHT----LLGRIVQSIPTWVLQSETFQHHFQEYVKNRDR 306
BLAST of SMED30021475 vs. Ensembl Zebrafish
Match: hsd17b3 (hydroxysteroid (17-beta) dehydrogenase 3 [Source:ZFIN;Acc:ZDB-GENE-040426-1339]) HSP 1 Score: 165.236 bits (417), Expect = 3.350e-48 Identity = 99/283 (34.98%), Postives = 160/283 (56.54%), Query Frame = -3 Query: 56 PVSESKFDKIKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIAESVEGLPVGLLINNVG---AAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFLNKVLVRRSMMKLRDQASRKRDK 895 P+ E+ F S G W V+TG +DGIG+ + E+L+K+ ++I+ISRN+EKL ++++ VK I ADF K IY HI E++EGL +G+L+NNVG + P T+D L +R + D+++CN S V M RI+L ++ GVI+N+SS + + P+ T+YA+ K + F+ LQAE ++G + +Q PF V + ++G + + TAEEF S L+ L Q++G ITH+ L +++ VL + + + RD+ Sbjct: 37 PLPEAFF---TSLGKWAVITGGSDGIGRAYAEELSKQGMSVIIISRNQEKLDRAAKKIELNTGGKVKVIAADFTKDDIYGHITENIEGLDIGVLVNNVGILPSQIPCKLLETSD-LEERIY-DIVNCNVKSMVKMCRIVLPGMQQRRRGVILNVSSGIAKIPCPIYTLYAASKVFVERFSQGLQAEYISKG----VIIQTVAPFGVSTAMTGHQKPDMVTFTAEEFVRSSLKYLKTGDQTYGSITHT----LLGRIVQSIPTWVLQSETFQHHFQEYVKNRDR 306
BLAST of SMED30021475 vs. Ensembl Zebrafish
Match: hsd20b2 (hydroxysteroid (20-beta) dehydrogenase 2 [Source:ZFIN;Acc:ZDB-GENE-030804-21]) HSP 1 Score: 150.214 bits (378), Expect = 3.586e-42 Identity = 89/273 (32.60%), Postives = 148/273 (54.21%), Query Frame = -3 Query: 122 YKLKPVSESKFDKIKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKT-KIYDHIAESVEGLPVGLLINNVGAAY----------PSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFL 907 +K+ +SE +++YG W VVTG T GIG+ + E+LAKR N++LISR+EEKL ++E+ +K+ I ADF + IY I + +EGL +G+L+NNVG Y P P D+ +L+CN LS M R++L + + G+IIN+SS + + +P++++Y++ K+ + F+ L AE ++G I VQ PF V + ++ LV +A F L + + G +TH+ ++ L+ + P +L Sbjct: 37 FKVYVISEIWRTDLRTYGRWAVVTGATSGIGRAYAEELAKRGLNIVLISRSEEKLHRVAKEIEDKYNQKTHVIQADFTEGHSIYSTITKQLEGLEIGILVNNVGMNYIGVLANFLDVPDP---------DQRITQVLNCNTLSVTQMCRVILPGMVERGKGLIINISSEAGYQPVPMVSLYSATKAFVTYFSLGLNAEYRSKG----ITVQCVAPFMVSTNMTHNVPVNPLVKSAASFARDALNTVGYTTYTSGCLTHALQHIVLSIVFPGWL 296
BLAST of SMED30021475 vs. Ensembl Xenopus
Match: hsd17b12 (hydroxysteroid (17-beta) dehydrogenase 12 [Source:NCBI gene;Acc:549988]) HSP 1 Score: 182.956 bits (463), Expect = 1.011e-54 Identity = 92/243 (37.86%), Postives = 146/243 (60.08%), Query Frame = -3 Query: 131 GNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRK-TKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIP 856 G W VVTG TDGIGK + E+LAKR N++LISR+ EKL ++++ EKF++ K I ADF K T+IY I + L +G+L+NNVG +Y P+++ + M++ N S MTR++L + + GVI+N+SSAS +P+LT+Y++ K+ ++ F+ LQAE ++G + VQ+ PF+V +KL+ I+ + P+ E + S L + Q+ GY+ H+ W L+P Sbjct: 56 GKWAVVTGATDGIGKAYAEELAKRGMNIVLISRSPEKLEEVAKQIKEKFKVETKIIAADFGKPTEIYGRIESGLRDLEIGVLVNNVGVSYEHPEYFLEIPDLENTLDKMININITSVCQMTRLVLPGMLGRGRGVILNISSASGMYPVPLLTVYSATKAFVDFFSRGLQAEYRSKG----VTVQSVLPFYVATKLAKIRKPTWDKPSPETYVQSALNTVGLQTQTNGYLPHAIMGWISTSLVP 294
BLAST of SMED30021475 vs. Ensembl Xenopus
Match: hsd17b12 (hydroxysteroid (17-beta) dehydrogenase 12 [Source:NCBI gene;Acc:549988]) HSP 1 Score: 177.563 bits (449), Expect = 1.071e-52 Identity = 91/243 (37.45%), Postives = 145/243 (59.67%), Query Frame = -3 Query: 131 GNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRK-TKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIP 856 G W VVTG TDGIGK + E+LAKR N++LISR+ EKL ++++ EKF++ K I ADF K T+IY I + L +G+L+NNVG +Y P+++ + D + + H MTR++L + + GVI+N+SSAS +P+LT+Y++ K+ ++ F+ LQAE ++G + VQ+ PF+V +KL+ I+ + P+ E + S L + Q+ GY+ H+ W L+P Sbjct: 56 GKWAVVTGATDGIGKAYAEELAKRGMNIVLISRSPEKLEEVAKQIKEKFKVETKIIAADFGKPTEIYGRIESGLRDLEIGVLVNNVGVSYEHPEYFL--EIPDLENVSTNHT-------MTRLVLPGMLGRGRGVILNISSASGMYPVPLLTVYSATKAFVDFFSRGLQAEYRSKG----VTVQSVLPFYVATKLAKIRKPTWDKPSPETYVQSALNTVGLQTQTNGYLPHAIMGWISTSLVP 285
BLAST of SMED30021475 vs. Ensembl Xenopus
Match: hsd17b12 (hydroxysteroid (17-beta) dehydrogenase 12 [Source:NCBI gene;Acc:549988]) HSP 1 Score: 169.088 bits (427), Expect = 1.830e-49 Identity = 91/243 (37.45%), Postives = 146/243 (60.08%), Query Frame = -3 Query: 131 GNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRK-TKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIP 856 G W VVTG TDGIGK + E+LAKR N++LISR+ EKL ++++ EKF++ K I ADF K T+IY I + L +G+L+NNVG +Y P+++ + M++ N +++V RI+ L + GVI+N+SSAS +P+LT+Y++ K+ ++ F+ LQAE ++G + VQ+ PF+V +KL+ I+ + P+ E + S L + Q+ GY+ H+ W L+P Sbjct: 56 GKWAVVTGATDGIGKAYAEELAKRGMNIVLISRSPEKLEEVAKQIKEKFKVETKIIAADFGKPTEIYGRIESGLRDLEIGVLVNNVGVSYEHPEYFLEIPDLENTLDKMININ-ITSVCQVRIV---GFLGR-GVILNISSASGMYPVPLLTVYSATKAFVDFFSRGLQAEYRSKG----VTVQSVLPFYVATKLAKIRKPTWDKPSPETYVQSALNTVGLQTQTNGYLPHAIMGWISTSLVP 289
BLAST of SMED30021475 vs. Ensembl Xenopus
Match: hsd17b12 (hydroxysteroid (17-beta) dehydrogenase 12 [Source:NCBI gene;Acc:549988]) HSP 1 Score: 166.007 bits (419), Expect = 2.631e-48 Identity = 88/243 (36.21%), Postives = 138/243 (56.79%), Query Frame = -3 Query: 131 GNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRK-TKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIP 856 G W VVTG TDGIGK + E+LAKR N++LISR+ EKL ++++ EKF++ K I ADF K T+IY I + L +G+L+NNVG +Y P+++ L L V + + + GVI+N+SSAS +P+LT+Y++ K+ ++ F+ LQAE ++G + VQ+ PF+V +KL+ I+ + P+ E + S L + Q+ GY+ H+ W L+P Sbjct: 56 GKWAVVTGATDGIGKAYAEELAKRGMNIVLISRSPEKLEEVAKQIKEKFKVETKIIAADFGKPTEIYGRIESGLRDLEIGVLVNNVGVSYEHPEYF-------------LEIPDLENVSTNHTVQQLPLTDPVGVILNISSASGMYPVPLLTVYSATKAFVDFFSRGLQAEYRSKG----VTVQSVLPFYVATKLAKIRKPTWDKPSPETYVQSALNTVGLQTQTNGYLPHAIMGWISTSLVP 281
BLAST of SMED30021475 vs. Ensembl Xenopus
Match: hsd17b12 (hydroxysteroid (17-beta) dehydrogenase 12 [Source:NCBI gene;Acc:549988]) HSP 1 Score: 161.384 bits (407), Expect = 1.223e-46 Identity = 86/243 (35.39%), Postives = 133/243 (54.73%), Query Frame = -3 Query: 131 GNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRK-TKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIP 856 G W VVTG TDGIGK + E+LAKR N++LISR+ EKL ++++ EKF++ K I ADF K T+IY I + L +G+L+NNVG +Y P+++ + M++ N S MTR++L + + GVI+N+SSAS +P+LT+Y++ KS+L PF+V +KL+ I+ + P+ E + S L + Q+ GY+ H+ W L+P Sbjct: 56 GKWAVVTGATDGIGKAYAEELAKRGMNIVLISRSPEKLEEVAKQIKEKFKVETKIIAADFGKPTEIYGRIESGLRDLEIGVLVNNVGVSYEHPEYFLEIPDLENTLDKMININITSVCQMTRLVLPGMLGRGRGVILNISSASGMYPVPLLTVYSATKSVL--------------------------PFYVATKLAKIRKPTWDKPSPETYVQSALNTVGLQTQTNGYLPHAIMGWISTSLVP 272
BLAST of SMED30021475 vs. Ensembl Mouse
Match: Hsd17b12 (hydroxysteroid (17-beta) dehydrogenase 12 [Source:MGI Symbol;Acc:MGI:1926967]) HSP 1 Score: 183.341 bits (464), Expect = 4.017e-55 Identity = 95/267 (35.58%), Postives = 157/267 (58.80%), Query Frame = -3 Query: 56 GNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFLNKVLVRRSMMKLRDQASRKRDK 856 G W VVTG TDGIGK + E+LAKR ++LISR+++KL S + EKF + + I DF IYD I + GL +G+L+NNVG +Y P+++ D +++ N LS +TR++L + + GVI+N+SSAS L +P+LT+Y++ K+ ++ F+ CL E ++G IFVQ+ P+ V +KL+ I+ P+AE F S ++ + ++ GY+ HS +N ++P+++ ++ LR++ +KR K Sbjct: 50 GEWAVVTGGTDGIGKAYAEELAKRGMKIVLISRSQDKLNQVSNNIKEKFNVETRTIAVDFSLDDIYDKIKTGLSGLEIGVLVNNVGMSYEYPEYFLEIPDLDNTIKKLININVLSVCKVTRLVLPGMVERSKGVILNISSASGMLPVPLLTIYSATKAFVDFFSQCLHEEYKSKG----IFVQSVMPYLVATKLAKIQKPTLDKPSAETFVKSAIKTVGLQTRTTGYVIHSLMG-SINSIMPRWMYFKIIMGFSKSLRNRYLKKRKK 311
BLAST of SMED30021475 vs. Ensembl Mouse
Match: Hsdl1 (hydroxysteroid dehydrogenase like 1 [Source:MGI Symbol;Acc:MGI:1919802]) HSP 1 Score: 153.295 bits (386), Expect = 1.401e-43 Identity = 91/279 (32.62%), Postives = 151/279 (54.12%), Query Frame = -3 Query: 89 PVSESKFDKIKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADF-RKTKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKF------LVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFL---NKVLVRRSMMK 895 P S+ D IK YG W V++G TDGIGK + E+LA N+ILIS+ EEKL ++ + + +R+ + ADF R +IY I E++ +G+L+N+VGA YP P +++ + + D+++ N + LM I+L + ++ G I+ +SS S P L +++ K+ L+ F+ LQ E ++G IFVQ+ PF+V S SG F L P+ + + L + ++ GY +HS + F + +P++L L+ RS+ K Sbjct: 33 PRLGSRPDLIKQYGRWAVISGATDGIGKAYAEELASHGLNVILISQEEEKLQAAAKHIADTYRVETLVLVADFSRGREIYAPIREALRDRDIGILVNDVGAFYPYPQYFS--QVPEDTLWDIVNVNIAAASLMVHIVLPGMVERKKGAIVTVSSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKG----IFVQSLIPFYVTS--SGAAPASFLHRCPWLAPSPRVYAQHAVSTLGISKRTTGYWSHSIQFLF-AQYMPEWLWVWGANLLNRSLRK 302
BLAST of SMED30021475 vs. Ensembl Mouse
Match: Hsdl1 (hydroxysteroid dehydrogenase like 1 [Source:MGI Symbol;Acc:MGI:1919802]) HSP 1 Score: 152.525 bits (384), Expect = 4.519e-43 Identity = 91/279 (32.62%), Postives = 151/279 (54.12%), Query Frame = -3 Query: 89 PVSESKFDKIKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADF-RKTKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKF------LVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFL---NKVLVRRSMMK 895 P S+ D IK YG W V++G TDGIGK + E+LA N+ILIS+ EEKL ++ + + +R+ + ADF R +IY I E++ +G+L+N+VGA YP P +++ + + D+++ N + LM I+L + ++ G I+ +SS S P L +++ K+ L+ F+ LQ E ++G IFVQ+ PF+V S SG F L P+ + + L + ++ GY +HS + F + +P++L L+ RS+ K Sbjct: 54 PRLGSRPDLIKQYGRWAVISGATDGIGKAYAEELASHGLNVILISQEEEKLQAAAKHIADTYRVETLVLVADFSRGREIYAPIREALRDRDIGILVNDVGAFYPYPQYFS--QVPEDTLWDIVNVNIAAASLMVHIVLPGMVERKKGAIVTVSSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKG----IFVQSLIPFYVTS--SGAAPASFLHRCPWLAPSPRVYAQHAVSTLGISKRTTGYWSHSIQFLF-AQYMPEWLWVWGANLLNRSLRK 323
BLAST of SMED30021475 vs. Ensembl Mouse
Match: Hsd17b3 (hydroxysteroid (17-beta) dehydrogenase 3 [Source:MGI Symbol;Acc:MGI:107177]) HSP 1 Score: 147.902 bits (372), Expect = 1.475e-41 Identity = 83/260 (31.92%), Postives = 143/260 (55.00%), Query Frame = -3 Query: 92 IKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDR-DFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFLNKVLVRRSMM 868 ++S G W V+TG DGIGK + +LA+ N++LISR EKL ++E+ VK + ADF + IYDHI E +EGL +G+L+NNVG P F+ + LS + +++HCN S V MT+++LK ++ G+I+N+SS ++ P+ ++Y++ K+ + F+ L E +G I +Q TP+ + + ++ K + TA+EF L+ + +S G + H LN++ + +R ++ Sbjct: 40 LRSMGQWAVITGAGDGIGKAYSFELARHGLNVVLISRTLEKLQTIAEEIERTTGSCVKIVQADFTREDIYDHIKEHLEGLEIGILVNNVGML---PSFFPSHFLSTSGESQNLIHCNITSVVKMTQLVLKHMESRRKGLILNISSGAALRPWPLYSLYSASKAFVYTFSKALSVEYRDKG----IIIQVLTPYSISTPMTKYLNNK-MTKTADEFVKESLKYVTIGAESCGCLAHEIIAIILNRIPSRIFYSSTAQRFLL 291
BLAST of SMED30021475 vs. Ensembl Mouse
Match: Hsd17b3 (hydroxysteroid (17-beta) dehydrogenase 3 [Source:MGI Symbol;Acc:MGI:107177]) HSP 1 Score: 147.902 bits (372), Expect = 1.475e-41 Identity = 83/260 (31.92%), Postives = 143/260 (55.00%), Query Frame = -3 Query: 92 IKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDR-DFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFLNKVLVRRSMM 868 ++S G W V+TG DGIGK + +LA+ N++LISR EKL ++E+ VK + ADF + IYDHI E +EGL +G+L+NNVG P F+ + LS + +++HCN S V MT+++LK ++ G+I+N+SS ++ P+ ++Y++ K+ + F+ L E +G I +Q TP+ + + ++ K + TA+EF L+ + +S G + H LN++ + +R ++ Sbjct: 40 LRSMGQWAVITGAGDGIGKAYSFELARHGLNVVLISRTLEKLQTIAEEIERTTGSCVKIVQADFTREDIYDHIKEHLEGLEIGILVNNVGML---PSFFPSHFLSTSGESQNLIHCNITSVVKMTQLVLKHMESRRKGLILNISSGAALRPWPLYSLYSASKAFVYTFSKALSVEYRDKG----IIIQVLTPYSISTPMTKYLNNK-MTKTADEFVKESLKYVTIGAESCGCLAHEIIAIILNRIPSRIFYSSTAQRFLL 291
BLAST of SMED30021475 vs. UniProt/SwissProt
Match: sp|O70503|DHB12_MOUSE (Very-long-chain 3-oxoacyl-CoA reductase OS=Mus musculus OX=10090 GN=Hsd17b12 PE=1 SV=1) HSP 1 Score: 183.341 bits (464), Expect = 2.810e-54 Identity = 95/267 (35.58%), Postives = 157/267 (58.80%), Query Frame = -3 Query: 56 GNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFLNKVLVRRSMMKLRDQASRKRDK 856 G W VVTG TDGIGK + E+LAKR ++LISR+++KL S + EKF + + I DF IYD I + GL +G+L+NNVG +Y P+++ D +++ N LS +TR++L + + GVI+N+SSAS L +P+LT+Y++ K+ ++ F+ CL E ++G IFVQ+ P+ V +KL+ I+ P+AE F S ++ + ++ GY+ HS +N ++P+++ ++ LR++ +KR K Sbjct: 50 GEWAVVTGGTDGIGKAYAEELAKRGMKIVLISRSQDKLNQVSNNIKEKFNVETRTIAVDFSLDDIYDKIKTGLSGLEIGVLVNNVGMSYEYPEYFLEIPDLDNTIKKLININVLSVCKVTRLVLPGMVERSKGVILNISSASGMLPVPLLTIYSATKAFVDFFSQCLHEEYKSKG----IFVQSVMPYLVATKLAKIQKPTLDKPSAETFVKSAIKTVGLQTRTTGYVIHSLMG-SINSIMPRWMYFKIIMGFSKSLRNRYLKKRKK 311
BLAST of SMED30021475 vs. UniProt/SwissProt
Match: sp|Q28IU1|DHB12_XENTR (Very-long-chain 3-oxoacyl-CoA reductase OS=Xenopus tropicalis OX=8364 GN=hsd17b12 PE=2 SV=1) HSP 1 Score: 182.956 bits (463), Expect = 5.356e-54 Identity = 92/243 (37.86%), Postives = 146/243 (60.08%), Query Frame = -3 Query: 131 GNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRK-TKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIP 856 G W VVTG TDGIGK + E+LAKR N++LISR+ EKL ++++ EKF++ K I ADF K T+IY I + L +G+L+NNVG +Y P+++ + M++ N S MTR++L + + GVI+N+SSAS +P+LT+Y++ K+ ++ F+ LQAE ++G + VQ+ PF+V +KL+ I+ + P+ E + S L + Q+ GY+ H+ W L+P Sbjct: 56 GKWAVVTGATDGIGKAYAEELAKRGMNIVLISRSPEKLEEVAKQIKEKFKVETKIIAADFGKPTEIYGRIESGLRDLEIGVLVNNVGVSYEHPEYFLEIPDLENTLDKMININITSVCQMTRLVLPGMLGRGRGVILNISSASGMYPVPLLTVYSATKAFVDFFSRGLQAEYRSKG----VTVQSVLPFYVATKLAKIRKPTWDKPSPETYVQSALNTVGLQTQTNGYLPHAIMGWISTSLVP 294
BLAST of SMED30021475 vs. UniProt/SwissProt
Match: sp|Q6QA33|DH12B_DANRE (Very-long-chain 3-oxoacyl-CoA reductase-B OS=Danio rerio OX=7955 GN=hsd17b12b PE=2 SV=2) HSP 1 Score: 182.185 bits (461), Expect = 8.778e-54 Identity = 97/253 (38.34%), Postives = 150/253 (59.29%), Query Frame = -3 Query: 116 KIKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIP-KFLNK 871 + S G W VVTG TDGIGK + E+LA+R F ++LISR +EKL S+ + K+++ K I+ADF IY I + GL +G+L+NNVG +Y P+F+ D +M++ N +S MTR++L + + GVI+N++SAS +P+LT+Y+S K+ ++ F+ L AE ++G I +Q+ PF+V +KLS I+ +PT E + + L + QS GY+ H+ W L+P K LNK Sbjct: 43 RASSLGKWAVVTGATDGIGKAYAEELARRGFAIVLISRTQEKLDEVSKAIESKYKVETKTISADFGSVDIYPKIESGLAGLEIGVLVNNVGVSYSYPEFFLNIPDVDSFINNMININIMSVCQMTRLVLPRMVDRSKGVILNVASASGMYPVPLLTLYSSTKAFVDFFSRGLDAEYKSKG----IIIQSVLPFYVTTKLSKIRKPTLDIPTPERYVKAQLSTIGLQTQSNGYLPHAIMGWVTASLLPAKLLNK 291
BLAST of SMED30021475 vs. UniProt/SwissProt
Match: sp|Q6P7R8|DHB12_RAT (Very-long-chain 3-oxoacyl-CoA reductase OS=Rattus norvegicus OX=10116 GN=Hsd17b12 PE=2 SV=1) HSP 1 Score: 180.644 bits (457), Expect = 3.862e-53 Identity = 90/245 (36.73%), Postives = 148/245 (60.41%), Query Frame = -3 Query: 122 GNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFL 856 G W VVTG TDGIGK + E+LAKR ++LISR+++KL S + EKF + + I DF IYD I + GL +G+L+NNVG +Y P+++ D +++ N LS +TR++L + + GVI+N+SSAS L +P+LT+Y++ K+ ++ F+ CL E ++G IFVQ+ PF+V +KL+ I+ P+AE F S ++ + ++ GY+ H+ +N ++P+++ Sbjct: 50 GEWAVVTGGTDGIGKSYAEELAKRGMKIVLISRSQDKLKEVSNNIKEKFNVETRTIAVDFSLDDIYDKIKTGLSGLEIGVLVNNVGMSYEYPEYFLEIPDLDNTIKKLININVLSICKVTRLVLPGMVERSKGVILNISSASGMLPVPLLTVYSATKAFVDFFSQCLHEEYKSKG----IFVQSVLPFFVATKLAKIRKPTLDKPSAETFVKSAIKTVGLQTRTTGYVIHAIMG-SINSILPRWI 289
BLAST of SMED30021475 vs. UniProt/SwissProt
Match: sp|Q4R5G7|DHB12_MACFA (Very-long-chain 3-oxoacyl-CoA reductase OS=Macaca fascicularis OX=9541 GN=HSD17B12 PE=2 SV=1) HSP 1 Score: 179.104 bits (453), Expect = 1.320e-52 Identity = 88/240 (36.67%), Postives = 141/240 (58.75%), Query Frame = -3 Query: 137 GNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKL 856 G W VVTG TDGIGK + E+LAKR ++LISR+++KL S E+ EKF++ + I DF IYD I + GL +G+L+NNVG +Y P+++ D M++ N LS MT+++L + + G I+N+SS S +P+LT+Y++ K+ ++ F+ CL E ++G IFVQ+ P++V +KL+ I+ PT E F S ++ + ++ GY+ H W ++ L Sbjct: 50 GEWAVVTGGTDGIGKSYAEELAKRGMKVVLISRSQDKLDQVSSEIKEKFKVETRTIAVDFTLEDIYDKIKTGLAGLEIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKMTQLVLPGMVERSKGAILNISSGSGMFPVPLLTIYSATKTFVDFFSQCLHEEYRSKG----IFVQSVLPYFVATKLAKIRKPTLDKPTPETFVKSAIKTVGLQSRTNGYLIHVLMGWIISNL 285
BLAST of SMED30021475 vs. TrEMBL
Match: A0A3M7SUC4 (Very-long-chain 3-oxoacyl-reductase OS=Brachionus plicatilis OX=10195 GN=BpHYR1_039333 PE=3 SV=1) HSP 1 Score: 202.986 bits (515), Expect = 2.946e-59 Identity = 104/274 (37.96%), Postives = 165/274 (60.22%), Query Frame = -3 Query: 50 IKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADF-RKTKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFLNKVLVRRSMMKLRDQASRKRDKIK 868 +K G+W VVTG TDGIGK + EKLA NL+LISR E+KL Q++E+ EKF++ K I ADF + IY I + + GL +G+L+NNVG +YP P+F+ A +++ DM++CN S MT I+L + + K+ G+IIN +S S + P+LT+Y++ K+ ++ F+ L E ++G I VQ+ P++V +KLS ++ R F+ PT EF S L + + G + H+ + W ++P L + M+ +R +A RK K++ Sbjct: 47 LKKIGSWAVVTGCTDGIGKAYAEKLANLGLNLVLISRTEQKLKNQAKEIEEKFKVDTKIIAADFCEQNSIYSEIKQQLTGLDIGILVNNVGVSYPYPEFFDAFAKNEKAVSDMINCNITSVTKMTAIVLPTMIEKRKGLIINNASGSGRIPTPLLTVYSASKAYVDFFSRALNTEYKSKG----IVVQSLCPYFVSTKLSALR-RNFMTPTPAEFVSSALATVNSQPVTNGCLIHNLQGWLYEDVVPSALVDKMTFNMMLGVRAKAIRKAKKLE 315
BLAST of SMED30021475 vs. TrEMBL
Match: C3Y616 (Uncharacterized protein OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_267231 PE=3 SV=1) HSP 1 Score: 200.29 bits (508), Expect = 2.367e-58 Identity = 106/273 (38.83%), Postives = 163/273 (59.71%), Query Frame = -3 Query: 50 IKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFLNKVLVRRSMMKLRDQASRKRDKIK 868 IK+ G+W VVTG+TDGIGK + E+LA R N++LISR E+KL + E+ K + K + ADF IYD+I+ +EGL + L+NNVG Y PDFY A+ +D D + ML+ N LS V MTRI+L + ++ GVI+N+SSAS + P+L++Y++ K+ ++ F+ CL E ++G I +Q+ TP +V +KLSGI+ P+ + S L + +FGY TH+ W + L+P+ L + + +R A +K + K Sbjct: 40 IKNCGSWAVVTGSTDGIGKAYAEELAARGLNIVLISRTEDKLKAVAAEIEGKAGVQTKIVVADFSSADIYDNISLQLEGLDIARLVNNVGVGYKFPDFY-ANTPADMDEM-MLNVNSLSVVKMTRIVLPGMVERKKGVILNISSASGVIPTPLLSLYSASKAFVDYFSRCLAQEYRSKG----IIIQSVTPNFVATKLSGIRKTSLFAPSPTSYVRSALNTVGLADHTFGYSTHALGGWLFD-LLPQRLYMSVSMSIFLGVRKAALKKLQRKK 305
BLAST of SMED30021475 vs. TrEMBL
Match: A0A3Q3KAP3 (Hydroxysteroid (17-beta) dehydrogenase 12a OS=Monopterus albus OX=43700 PE=3 SV=1) HSP 1 Score: 198.364 bits (503), Expect = 2.723e-57 Identity = 106/272 (38.97%), Postives = 160/272 (58.82%), Query Frame = -3 Query: 77 GNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSD-RDFI-DMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPK----FLNKVLVRRSMM------KLRDQ 856 G W VVTG TDGIGK + E+LA+R F ++LISR+++KL ++ L E++++ K I DF KT IY I E + GL +G+L+NNVG +YP P++Y H+ D DFI +M++ N S MTR++L + + GVI+N+SSAS +P+LT+Y++ K+ ++ F+ LQ E QG I +Q+ PF+V +K++ IK PT E + + L + Q+ GY H+ W KL+P +L + RR KLRDQ Sbjct: 56 GKWAVVTGATDGIGKSYAEELARRGFAMVLISRSQDKLDDVAKSLKEQYKVETKTIAVDFGKTDIYSKINEGLAGLEIGVLVNNVGVSYPYPEYYL--HIPDLDDFITNMINVNMTSVCQMTRLVLPRMVERSKGVILNISSASGMYPLPLLTVYSATKAFVDFFSRGLQEEYRRQG----IIIQSVLPFYVATKMTRIKKPTLDKPTPERYVAAELNTVGLQSQTNGYFPHAVMGWVTTKLVPSSIVIYLGAGMNRRQRTGYLQRRKLRDQ 321
BLAST of SMED30021475 vs. TrEMBL
Match: A0A3P8QX52 (Hydroxysteroid (17-beta) dehydrogenase 12a OS=Astatotilapia calliptera OX=8154 PE=3 SV=1) HSP 1 Score: 194.897 bits (494), Expect = 4.634e-56 Identity = 102/271 (37.64%), Postives = 163/271 (60.15%), Query Frame = -3 Query: 50 GNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRD-FI-DMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFLNKVLVRRSMMKLRDQASRKRDKIK 856 G W VVTG TDGIGK + E+LA+R F ++LISR++EKL ++ + E+F++ + I DF KT IY I E + GL +G+L+NNVG +YP P++Y H+ D D FI +M++ N S MTR++L + GVI+N+SSAS +P+LT+Y++ K+ ++ F+ LQ E QG I +Q+ PF+V++K++ IK PT E + + L + Q+ GY H+ W KL+P + + + +M +L+ +R K++ Sbjct: 53 GKWAVVTGATDGIGKSYAEELARRGFAMMLISRSQEKLDDVARSIEEQFKVETRTIAVDFGKTDIYSKIEEGLAGLEIGVLVNNVGVSYPYPEYYL--HIPDLDNFITNMINVNMTSVCQMTRLVLPRMCERSKGVILNISSASGMYPLPLLTVYSATKAFVDFFSRGLQEEYRRQG----ILIQSVLPFFVVTKMTRIKKPTLDKPTPERYVAAELTTVGLQSQTNGYFPHAVMGWVTTKLVPTSI-VIFLGATMNRLQRTGYLQRRKLR 316
BLAST of SMED30021475 vs. TrEMBL
Match: A0A3B4FSS6 (Hydroxysteroid (17-beta) dehydrogenase 12a OS=Pundamilia nyererei OX=303518 PE=3 SV=1) HSP 1 Score: 194.897 bits (494), Expect = 4.634e-56 Identity = 102/271 (37.64%), Postives = 163/271 (60.15%), Query Frame = -3 Query: 50 GNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRD-FI-DMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFLNKVLVRRSMMKLRDQASRKRDKIK 856 G W VVTG TDGIGK + E+LA+R F ++LISR++EKL ++ + E+F++ + I DF KT IY I E + GL +G+L+NNVG +YP P++Y H+ D D FI +M++ N S MTR++L + GVI+N+SSAS +P+LT+Y++ K+ ++ F+ LQ E QG I +Q+ PF+V++K++ IK PT E + + L + Q+ GY H+ W KL+P + + + +M +L+ +R K++ Sbjct: 53 GKWAVVTGATDGIGKSYAEELARRGFAMMLISRSQEKLDDVARSIEEQFKVETRTIAVDFGKTDIYSKIEEGLAGLEIGVLVNNVGVSYPYPEYYL--HIPDLDNFITNMINVNMTSVCQMTRLVLPRMCERSKGVILNISSASGMYPLPLLTVYSATKAFVDFFSRGLQEEYRRQG----ILIQSVLPFFVVTKMTRIKKPTLDKPTPERYVAAELTTVGLQSQTNGYFPHAVMGWVTTKLVPTSI-VIFLGATMNRLQRTGYLQRRKLR 316
BLAST of SMED30021475 vs. Ensembl Cavefish
Match: hsd17b12b (very-long-chain 3-oxoacyl-CoA reductase-B-like [Source:NCBI gene;Acc:103024613]) HSP 1 Score: 186.422 bits (472), Expect = 2.151e-56 Identity = 96/267 (35.96%), Postives = 154/267 (57.68%), Query Frame = -3 Query: 56 GNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFLNKVLVRRSMMKLRDQASRKRDK 856 G W VVTG TDGIGK + E+LA+R F+++LISR +EKL S+ + K+++ K I+ADF IY I + L +G+L+NNVG +Y P+F+ D M++ N S MTR++L + + GVI+N+SSAS +P+LT+Y+S K+ ++ F+ L AE ++G + +Q+ PF+V +KLS IK +PT E + S + + +Q+ GY+ H+ W L+P L LV + + R + +K+ + Sbjct: 51 GAWAVVTGATDGIGKAYAEELARRGFSIVLISRTQEKLDEVSKAIESKYKVQTKTISADFGCVDIYPKIQAGLANLQIGILVNNVGVSYSYPEFFLNVPNLDNVISSMININISSVCQMTRLVLPGMVERSKGVILNISSASGMYPVPLLTLYSSSKAFVDFFSRALDAEYKSKG----VIIQSVLPFYVTTKLSKIKRASLDIPTPERYVRSQISTVGLQNQTNGYLPHAVMGWVTTALLPARLVSNLVMKMGLSQRARYLKKQKQ 313
BLAST of SMED30021475 vs. Ensembl Cavefish
Match: hsd17b12a (hydroxysteroid 17-beta dehydrogenase 12 [Source:NCBI gene;Acc:103027081]) HSP 1 Score: 186.422 bits (472), Expect = 2.533e-56 Identity = 93/244 (38.11%), Postives = 148/244 (60.66%), Query Frame = -3 Query: 131 GNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRD-FID-MLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIP 856 G W VVTG TDGIGK + E+LA+R F+++LISR +EKL +Q L ++++ K + DF + IY I ++ GL +G+L+NNVG +YP P+F+ H+ D D FI+ M++ N S MTR++L + GVI+N+SSAS +P+LT+Y+S K+ ++ F+ LQAE ++G I +Q+ PF+V +K++ I+ PT + + + L + Q+ GY H+ W L+P Sbjct: 48 GKWAVVTGATDGIGKSYAEELARRGFSMMLISRTQEKLDDVAQSLERRYKVETKTVAVDFGQVDIYPKIETALSGLEIGVLVNNVGISYPYPEFFL--HIPDLDNFINTMINVNITSVCQMTRLVLPRMEARAKGVILNISSASGMYPVPLLTVYSSTKAFVDFFSRGLQAEYKSKG----IIIQSVLPFFVATKMTKIRKPTLDKPTPDRYVAAELTTVGLQDQTNGYFPHAVMGWLTTVLVP 285
BLAST of SMED30021475 vs. Ensembl Cavefish
Match: hsd17b12a (hydroxysteroid 17-beta dehydrogenase 12 [Source:NCBI gene;Acc:103027081]) HSP 1 Score: 172.555 bits (436), Expect = 4.831e-51 Identity = 89/243 (36.63%), Postives = 144/243 (59.26%), Query Frame = -3 Query: 131 GNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRD-FIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIP 856 G W VVTG TDGIGK + E+LA+R F+++LISR +EKL +Q L ++++ K + DF + IY I ++ GL +G+L+NNVG +YP P+F+ H+ D D FI+ + +++V + L K GVI+N+SSAS +P+LT+Y+S K+ ++ F+ LQAE ++G I +Q+ PF+V +K++ I+ PT + + + L + Q+ GY H+ W L+P Sbjct: 48 GKWAVVTGATDGIGKSYAEELARRGFSMMLISRTQEKLDDVAQSLERRYKVETKTVAVDFGQVDIYPKIETALSGLEIGVLVNNVGISYPYPEFFL--HIPDLDNFINTMINVNITSVCQFKPLFPHFRAK--GVILNISSASGMYPVPLLTVYSSTKAFVDFFSRGLQAEYKSKG----IIIQSVLPFFVATKMTKIRKPTLDKPTPDRYVAAELTTVGLQDQTNGYFPHAVMGWLTTVLVP 282
BLAST of SMED30021475 vs. Ensembl Cavefish
Match: hsd17b3 (hydroxysteroid 17-beta dehydrogenase 3 [Source:NCBI gene;Acc:103031519]) HSP 1 Score: 149.058 bits (375), Expect = 4.603e-42 Identity = 86/256 (33.59%), Postives = 140/256 (54.69%), Query Frame = -3 Query: 137 PVSESKFDKIKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIAESVEGLPVGLLINNVG---AAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKL 895 P+ E+ F S G W V+TG +DGIGK + ++LA+R N+++ISR +EKL ++E+ K V+ I ADF K IY I E++EGL +GLL+NNVG P TA+ + +++CN + V M I+L + + G+++N+SS + + P +YA+ K+ + F+ L AE + G I +Q+ +PF V + ++G + TAEEF + L L Q++G + HS W + + Sbjct: 37 PLPENFFT---SKGKWAVITGGSDGIGKAYAQELARRGLNVVIISRTKEKLDGVAREIELKTEAKVRAIAADFTKDDIYRDIEENIEGLDIGLLVNNVGILPTQLPCILLETAN--LEEKINQVINCNVKTMVKMCHIVLPGMVERGRGIVLNVSSGIAKIPCPTYALYAASKAFVERFSQGLLAEYRSSG----ILIQSVSPFGVSTTMTGHPKPDLITFTAEEFVRNSLMYLKTGEQTYGSVRHSILGWVIQAI 283
BLAST of SMED30021475 vs. Ensembl Cavefish
Match: hsd20b2 (very-long-chain 3-oxoacyl-CoA reductase-like [Source:NCBI gene;Acc:103033448]) HSP 1 Score: 149.443 bits (376), Expect = 5.527e-42 Identity = 86/264 (32.58%), Postives = 148/264 (56.06%), Query Frame = -3 Query: 122 YKLKPVSESKFDKIKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTK-IYDHIAESVEGLPVGLLINNVGAAYPSPDFYTAD-HLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFL 907 +K+ +SE ++ +G W VVTG T GIG+ + +LA+R +++LISR+EEKLL ++E+ ++R + I ADF + IY IA+ ++GL +G+L+NNV Y + D S++ +++CN LS MTR++L + + G+IIN+SS ++ P+L +Y++ K + F+ CL +E ++G I VQ PF V + ++ LV +AE F L + + + G +TH+ +N L+ P + Sbjct: 36 FKVYMLSEVWRTDVRKFGQWAVVTGATSGIGRAYALELARRGLDIVLISRSEEKLLQTAKEIESQYRRQTRIIQADFTGGESIYPAIAQQLKGLEIGILVNNVAMNYAEEFAHFLDVPDSEQRITQVINCNILSVTQMTRVILPHMVERGSGLIINLSSEAASKPQPMLALYSATKIFVTYFSRCLHSEYRSRG----ITVQCVAPFVVSTNMTNNVPVSPLVKSAESFARDALNTVGYSSFTSGCLTHALQNIALSIFFPAWF 295
BLAST of SMED30021475 vs. Ensembl Sea Lamprey
Match: hsd17b12b (hydroxysteroid (17-beta) dehydrogenase 12b [Source:NCBI gene;Acc:322626]) HSP 1 Score: 155.221 bits (391), Expect = 1.241e-45 Identity = 86/262 (32.82%), Postives = 150/262 (57.25%), Query Frame = -3 Query: 62 VVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTK-IYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFLNKVLVRRSMMKLRDQASRKR 844 VVTG TDGIGK + E++ K L L+ + +E+ E+F++ K + DF ++ IY + ++ LPVG+L+NNVG +Y P+++ D ++L+ N LS + MT+I+L + ++GGVIIN+SS S+ +P+L++Y++ K ++ F+ L E ++G I VQ+ PF+V S +S I+ +P AE F S L + +++GY+ H+ + W L+ ++P L ++++KL +Q R R Sbjct: 2 VVTGATDGIGKAYVEQMLKTDLPLRLVVCSSHNCAQIVREMSERFKVETKTVAVDFTASEEIYPKVLAALRDLPVGVLVNNVGISYTYPEYFLDIPNLDDMIKNILNVNVLSVLKMTQIILPGMLERKGGVIINISSGSALFPVPLLSLYSATKVFVDFFSRGLNTEYKSKG----IIVQSVLPFYVKSNMSRIQRATLNMPEAETFACSALATVGRQSRTYGYLPHALQAW-LSNMVP----TCLAMKTILKL-NQGIRAR 253
BLAST of SMED30021475 vs. Ensembl Sea Lamprey
Match: hsd17b12b (hydroxysteroid (17-beta) dehydrogenase 12b [Source:NCBI gene;Acc:322626]) HSP 1 Score: 150.214 bits (378), Expect = 9.458e-44 Identity = 84/263 (31.94%), Postives = 152/263 (57.79%), Query Frame = -3 Query: 62 VVTGTTDGIGKCFCEKLAKRKFNLILISRN-EEKLLIQSQELMEKFRISVKYITADFRKTK-IYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFLNKVLVRRSMMKLRDQASRKR 844 VVTG TDGIGK + E+++ R + +++ +L + + E+F++ K + DF ++ IY + ++ LPVG+L+NNVG +Y P+++ D ++L+ N LS + MT+I+L + ++GGVIIN+SS S+ +P+L++Y++ K ++ F+ L E ++G I VQ+ PF+V S +S I+ +P AE F S L + +++GY+ H+ + W L+ ++P L ++++KL +Q R R Sbjct: 2 VVTGATDGIGKAYVEQVSSRGRIMSPTAKSLPTRLGVAHVYVCERFKVETKTVAVDFTASEEIYPKVLAALRDLPVGVLVNNVGISYTYPEYFLDIPNLDDMIKNILNVNVLSVLKMTQIILPGMLERKGGVIINISSGSALFPVPLLSLYSATKVFVDFFSRGLNTEYKSKG----IIVQSVLPFYVKSNMSRIQRATLNMPEAETFACSALATVGRQSRTYGYLPHALQAW-LSNMVP----TCLAMKTILKL-NQGIRAR 254
BLAST of SMED30021475 vs. Ensembl Sea Lamprey
Match: dhrs7b (dehydrogenase/reductase (SDR family) member 7B [Source:NCBI gene;Acc:550454]) HSP 1 Score: 53.5286 bits (127), Expect = 2.288e-8 Identity = 53/208 (25.48%), Postives = 87/208 (41.83%), Query Frame = -3 Query: 272 YGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRI---------SVKYITADFRKTKIYDHIAESVEGL--PVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQG-GVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLS 859 +G VVVTG + G+G L+L R+ +L EL E+ RI + + + D AE V V +L++ G +Y TA + + ++ N + + LL S MLKQG G I+ +SS + IP + YA+ K + + L+AE+ G + V +P ++ + LS Sbjct: 54 HGKVVVVTGASSGLGLACARAFHAEGARLVLCGRDLRRLESLRDELSERVRILAPQGPEDRTPRVVPFDLGSPGEVARAAELVVAAHGRVDVLVSGAGISYRGEAALTAMDVHRQ----LMEVNYFGAIALLTALLPS-MLKQGEGHIVAISSVQGRIAIPFRSAYAASKHATQAYFDSLRAEVADSG----LKVTVVSPGYIRTNLS 252
BLAST of SMED30021475 vs. Ensembl Sea Lamprey
Match: kdsr (3-ketodihydrosphingosine reductase [Source:ZFIN;Acc:ZDB-GENE-040426-853]) HSP 1 Score: 49.2914 bits (116), Expect = 4.225e-7 Identity = 43/174 (24.71%), Postives = 78/174 (44.83%), Query Frame = -3 Query: 344 VTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFR--------ISVKYITADFRKTKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEI 841 VTG + GIGK + ++ + L++RNE KLL +E E ISV ++ DF + + A+ G PV +L+N G + + + ++F ++ N L +V + ++ ++ G ++ +SS + L + T Y+ K L LQ E+ Sbjct: 4 VTGGSSGIGKAIAIECVRQGACVTLVARNEAKLLQAKREAEEHVVNESQAVLCISVD-VSNDFNQVESVIKQAQEKLG-PVDMLVNAAGTSVAG----RFEDIKPQEFKRLMEVNYLGSVFTSLAVVPGMKERRKGRVVYVSSQAGQLGLYGFTAYSPTKFALRGLAEALQMEV 171
BLAST of SMED30021475 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010315.1 (pep scaffold:Pmarinus_7.0:GL479994:4152:14615:1 gene:ENSPMAG00000009341.1 transcript:ENSPMAT00000010315.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 49.2914 bits (116), Expect = 6.242e-7 Identity = 45/183 (24.59%), Postives = 83/183 (45.36%), Query Frame = -3 Query: 341 IKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRI---SVKYITADFRKTKIYDHIAESVEGL--PVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCML--KQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEID 868 +K G+ V VTG + GIG+ +LA+ L+L +R E +L + +E + + + D ++ ++V V +L+NN G + S F D R ++ N L+ V + R +L M GG+++ +SS + +P+ Y + K + N L++E+D Sbjct: 46 LKLRGHVVWVTGASSGIGEALARELARCGCQLVLSARREAELQRVRKNCLEDSSLKESDILVLPMDVLDLSTHEACTKAVLDRFGRVDVLVNNAGRSQRSL-FMDTDLCVYRTLFEL---NVLAPVSLARCVLPGMMAPGSHGGILLAVSSIAGLAGVPLSAGYCASKHAVQGAFNALRSELD 224
BLAST of SMED30021475 vs. Ensembl Yeast
Match: IFA38 (Microsomal beta-keto-reductase; contains oleate response element (ORE) sequence in the promoter region; mutants exhibit reduced VLCFA synthesis, accumulate high levels of dihydrosphingosine, phytosphingosine and medium-chain ceramides [Source:SGD;Acc:S000000363]) HSP 1 Score: 117.857 bits (294), Expect = 6.231e-31 Identity = 78/253 (30.83%), Postives = 132/253 (52.17%), Query Frame = -3 Query: 170 FDKIKS-YGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKI--YDHIAESVEGLPVGLLINNVGAAY--PSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRIL-------LKSCMLKQG--GVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQL---CENHQSFGYIT 877 FDK + G + +TG +DGIGK F ++AKR FNL+LISR + KL +EL ++ + VK + D + K Y+ I E LP+ +L+NNVG ++ P P T +++ +++ N +T+L+T+I+ +K+ K G G+I+ M S + P+L Y+ KS L ++N L E+ D I V+ + V S +S I+ ++P ++F S LR + C + + + +T Sbjct: 54 FDKYGAKTGKYCAITGASDGIGKEFARQMAKRGFNLVLISRTQSKLEALQKELEDQHHVVVKILAIDIAEDKESNYESIKELCAQLPITVLVNNVGQSHSIPVPFLET----EEKELRNIITINNTATLLITQIIAPKIVETVKAENKKSGTRGLILTMGSFGGLIPTPLLATYSGSKSFLQGWSNSLAGELSK----DAIDVELIISYLVTSSMSKIRRSSLMIPNPQQFVKSTLRSVGRRCGSQERYATMT 298
BLAST of SMED30021475 vs. Ensembl Yeast
Match: YMR226C (NADP(+)-dependent serine dehydrogenase and carbonyl reductase; acts on serine, L-allo-threonine, and other 3-hydroxy acids; green fluorescent protein fusion protein localizes to the cytoplasm and nucleus; may interact with ribosomes, based on co-purification experiments [Source:SGD;Acc:S000004839]) HSP 1 Score: 51.6026 bits (122), Expect = 3.991e-8 Identity = 44/182 (24.18%), Postives = 79/182 (43.41%), Query Frame = -3 Query: 344 VVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIY---------DHIAESVEGLP-----VGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEI 847 V++TG + GIGK + S + KL++ ++ L EK K I +F K++ + I +E LP + +L+NN G A S ++ D D+ N + + +T+ +L K G I+N+ S + P ++Y + K + FT+ L+ E+ Sbjct: 16 VLITGASAGIGKATA-------LEYLEASNGDMKLILAARRL-EKLEELKKTIDQEFPNAKVHVAQLDITQAEKIKPFIENLPQEFKDIDILVNNAGKALGSD---RVGQIATEDIQDVFDTNVTALINITQAVLPIFQAKNSGDIVNLGSIAGRDAYPTGSIYCASKFAVGAFTDSLRKEL 186
BLAST of SMED30021475 vs. Ensembl Nematostella
Match: EDO41444 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4B0]) HSP 1 Score: 163.31 bits (412), Expect = 8.334e-48 Identity = 90/252 (35.71%), Postives = 147/252 (58.33%), Query Frame = -3 Query: 122 IKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADF-RKTKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTR--KFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFL 868 +K YG+W VVTG TDGIG+C+ EKLA R N++LISR+ EKL Q + +F + K I DF ++Y + E + L +G+L+NNVG A F AD L ML+ N LS V+MT I+L + +Q GV++N+SS +P++++Y + K+ L+ F++CL +E ++G IFVQ P +V +K++G++ + PTA+++ + L + ++ G+ +HS W +IP ++ Sbjct: 47 LKRYGSWAVVTGCTDGIGRCYAEKLAGRGLNIVLISRSLEKLKQVQQHIESQFSVQTKIIVKDFGGNAEVYQDLDEQLSNLDIGILVNNVGMASMINRF--AD-LKIEVCWKMLNVNALSAVMMTHIVLPGMLSRQRGVVVNVSSLVGSDPMPLMSVYCATKAFLDFFSSCLHSEYSSKG----IFVQCVRPAFVATKMTGMRNKPGTAFTPTADQYVEQALGTIGVEQRTSGFWSHSLMAWVTFNIIPAWV 291
BLAST of SMED30021475 vs. Ensembl Nematostella
Match: EDO41442 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4A6]) HSP 1 Score: 142.51 bits (358), Expect = 7.912e-41 Identity = 78/233 (33.48%), Postives = 135/233 (57.94%), Query Frame = -3 Query: 152 VVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTK-IYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENW 847 +VVTG TDGIGK F +LA + NLILISR +EKL E+ +++ + I DF + IY+ + + GL +G+L+NNVG ++ P+F+T ++ D M++ N LS ++MT I+L + + G+++N+SS + P+L++Y+SCK+ ++ F+ CL E +G I VQ+ P +V +K+S I+ VP +E+ L + ++ G +H+ + + Sbjct: 5 LVVTGCTDGIGKSFAYQLAAQGINLILISRTKEKLENMEAEIKSAYKVDTRIIALDFSGSADIYEGLDVKLGGLDIGILVNNVGVSH-YPEFFT--NMKREDCWKMINVNDLSVIMMTHIILPGMVSRGKGLVLNLSSGAGLEPRPLLSVYSSCKAFVDFFSCCLHDEYSGKG----IIVQSVMPLYVATKMSRIRKPNLFVPGPDEYVKQVLGTVGVQSRTNGCWSHALQVY 230
BLAST of SMED30021475 vs. Ensembl Nematostella
Match: EDO41496 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4C5]) HSP 1 Score: 56.6102 bits (135), Expect = 3.901e-9 Identity = 63/274 (22.99%), Postives = 111/274 (40.51%), Query Frame = -3 Query: 104 LKPVSESKFDKIKSY-GNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIAESVEGLP--VGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEF-----TDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFLNKVLVR 901 + +++ F + KS G V++TG GIG+ LAK+ L+L N E L +QE+ + Y D RK + +A +VE V +LINN G + S+ D + N L+ + + + S M K G I++++S + + + Y + K L+ EI G F F +G+K + +P E + + + N ++ S +++L +IP + +LVR Sbjct: 19 FQALAQFVFPRRKSLRGETVLITGAASGIGRLTALILAKKGCKLVLWDINLEALKAVAQEI-QDLGAETHYFECDVRKKDEVEKVANAVEDQAGNVTILINNAGVVTGKKFL----NCSESDVMRTFQVNSLAHIWTIQRFIPSMMEKNRGHIVSIASVAGYFGLVGCVDYCASKFAAVGLIEALRREIHGLGKMGIEFTTICPHFTATGMFAGVKLKYPNLPGLGELKPEFVAEKIVDGIETNSRTVFIPFMSRISYYLQTVIPTHSSDMLVR 287
BLAST of SMED30021475 vs. Ensembl Nematostella
Match: EDO31654 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SXC4]) HSP 1 Score: 53.9138 bits (128), Expect = 1.797e-8 Identity = 47/200 (23.50%), Postives = 91/200 (45.50%), Query Frame = -3 Query: 260 GNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIAESVEGL-PVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKT 856 G +VTG + GIG + LA+ + L +R EE+L E++ +++ T K ++ + + L PV +L++ G Y + + + +D+ M+ NC + +L + + G I+ +SS++ P L +Y+ K + + L+ EI AG + V P V++++ G+KT Sbjct: 3 GQVAIVTGASSGIGAAVAKALAEAGVKVALAARREERLTQLRDEIIANGDVAISVKTDVTIKEQMESLVKRTDSTLGPVDILVSCAGVMY----YQMMKNCAMKDWEQMVDINCKGVMFGIGAVLPGMLERAKGHIVTISSSAGRKAFPGLAIYSGTKFFVEALSQGLRQEI----AGSGVKVTTIQPGDVVTEI-GLKT 193
BLAST of SMED30021475 vs. Ensembl Nematostella
Match: EDO35908 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SK77]) HSP 1 Score: 51.9878 bits (123), Expect = 1.072e-7 Identity = 51/190 (26.84%), Postives = 85/190 (44.74%), Query Frame = -3 Query: 344 KIKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYD-HIAESVEGL------------PVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQG-GVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEI 871 K + G+ +VTG + GIG+ +LA++ ++ L++RN+ KL E R V+ RK ++ + +SVE + PV LL N G A + DF +M++ N L +V T ++K M K+G G ++ SS I ++ Y+ K + F CL E+ Sbjct: 26 KTQINGSHAIVTGGSSGIGRALAVQLAQQGASVTLLARNKAKL--------EGARQRVEKHLQPGRKVSVFSVDLCQSVEAVQKVIDEACLALGPVNLLFNCAGYAVCG----VFEDTRPEDFKNMINTNYLGSVYPTYAVMKG-MKKRGCGHVVFTSSIGGQFGIFGMSAYSGSKFAVRGFAECLYMEV 202
BLAST of SMED30021475 vs. Ensembl Medaka
Match: hsd17b12a (very-long-chain 3-oxoacyl-CoA reductase-A [Source:NCBI gene;Acc:101163971]) HSP 1 Score: 186.808 bits (473), Expect = 2.842e-56 Identity = 98/273 (35.90%), Postives = 157/273 (57.51%), Query Frame = -3 Query: 38 GNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFLNKVLVRRSMMKLRDQASRKRDKIKNL*N 856 G W VVTG TDGIGK + E+LA+R F ++LISR++EKL ++ L E+F + K I DF KT IY I + GL +G+L+NNVG +Y P++Y D +M++ N S MTR++L + + GVI+N+SSAS +P+LT+Y++ K+ ++ F+ LQ E QG I +Q+ PF+V +K++ I+ PT E + + L + +Q+ GY H+ W KL+P + + + SM +++ R K++ + N Sbjct: 56 GKWAVVTGATDGIGKSYAEELARRGFAMMLISRSQEKLDDVAKSLEEQFGVETKTIAVDFGKTDIYPKIEAGLVGLEIGVLVNNVGVSYHYPEYYLNIPDLDNFLTNMINVNMTSVCQMTRLVLPGMVSRAKGVILNISSASGMYPLPLLTVYSATKAFMDFFSRGLQEEYRRQG----IIIQSVLPFFVATKMTRIRKPTLDKPTPERYVAAELTTVGLQNQTNGYFPHAVMGWVTTKLVPTSI-VIFLGASMNRVQRSGYLHRRKLREMKN 323
BLAST of SMED30021475 vs. Ensembl Medaka
Match: hsd17b12b (very-long-chain 3-oxoacyl-CoA reductase-B [Source:NCBI gene;Acc:101160884]) HSP 1 Score: 172.555 bits (436), Expect = 5.296e-51 Identity = 90/244 (36.89%), Postives = 145/244 (59.43%), Query Frame = -3 Query: 131 GNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRD-FID-MLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIP 856 G W VVTG TDGIGK + E+LA+R F+++LISR++EKL S+ + K + K I DF IY I + GL +G+L+NNVG +Y P+F+ ++ + D FID M++ N S MTR++L + ++ G I+N+SSAS +P+LT+Y++ K+ ++ F+ LQAE ++G I +Q+ PF+V +KLS I+ P + + + + + Q+ GY+ H+ W L+P Sbjct: 56 GKWAVVTGATDGIGKAYAEELARRGFSIVLISRSQEKLDEVSKAIAGKCGVETKTIAVDFSSVDIYPKIEAGLAGLEIGVLVNNVGISYSHPEFFL--NVPNLDTFIDTMVNINITSVCQMTRLVLPRMVERKKGAILNISSASGMYPVPLLTIYSASKAFVDFFSRGLQAEYKSKG----IIIQSVLPFFVATKLSKIRRATLDKPNPDRYVAAEINTVGLQTQTNGYLPHAVMGWVTTALLP 293
BLAST of SMED30021475 vs. Ensembl Medaka
Match: hsd17b12b (very-long-chain 3-oxoacyl-CoA reductase-B [Source:NCBI gene;Acc:101160884]) HSP 1 Score: 163.696 bits (413), Expect = 8.775e-48 Identity = 86/242 (35.54%), Postives = 137/242 (56.61%), Query Frame = -3 Query: 131 GNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIP 856 G W VVTG TDGIGK + E+LA+R F+++LISR++EKL S+ + K + K I DF IY I + GL +G+L+NNVG +Y P+F+ L+ L T MTR++L + ++ G I+N+SSAS +P+LT+Y++ K+ ++ F+ LQAE ++G I +Q+ PF+V +KLS I+ P + + + + + Q+ GY+ H+ W L+P Sbjct: 56 GKWAVVTGATDGIGKAYAEELARRGFSIVLISRSQEKLDEVSKAIAGKCGVETKTIAVDFSSVDIYPKIEAGLAGLEIGVLVNNVGISYSHPEFF-------------LNVPNLDT--MTRLVLPRMVERKKGAILNISSASGMYPVPLLTIYSASKAFVDFFSRGLQAEYKSKG----IIIQSVLPFFVATKLSKIRRATLDKPNPDRYVAAEINTVGLQTQTNGYLPHAVMGWVTTALLP 278
BLAST of SMED30021475 vs. Ensembl Medaka
Match: hsd17b3 (hydroxysteroid 17-beta dehydrogenase 3 [Source:NCBI gene;Acc:100125485]) HSP 1 Score: 133.65 bits (335), Expect = 8.707e-36 Identity = 82/261 (31.42%), Postives = 139/261 (53.26%), Query Frame = -3 Query: 119 PVSESKFDKIKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIAESVEGLPVGLLINNVGAAYPS--PDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFLN 895 P+SE+ F S G W VVTG ++GIG+ + LA+R N++++SR + L ++E+ V+ I ADF I+ I E ++ L VG+L+NNVG PS P + D+ +++CN + V M R++L ++ GVI+N+SS + + P+ T+YA+ K + F+ LQAE + +G I +Q PF V ++++G + + E+F + L+ L +++ G I H W L + K L+ Sbjct: 69 PISETFF---TSMGEWAVVTGASEGIGRAYAFALAERGMNIVIMSRTKSTLDQVAKEISNSTGQKVRVIIADFTDENIFSEIEEQLKDLCVGILVNNVG-ILPSFIPYRFLESEDLDQTITKVINCNVKTMVKMCRMILPQMDKRRKGVIVNISSGIASVPFPLYTLYAASKIFVERFSQGLQAEYENRG----ILIQAVAPFGVCTRMAGYQPPNRVTFLPEDFVKNSLQYLRAGNKTHGSICHIVLGWILQCIPLKVLH 321
BLAST of SMED30021475 vs. Ensembl Medaka
Match: hsd17b3 (hydroxysteroid 17-beta dehydrogenase 3 [Source:NCBI gene;Acc:100125485]) HSP 1 Score: 130.183 bits (326), Expect = 7.313e-35 Identity = 78/250 (31.20%), Postives = 133/250 (53.20%), Query Frame = -3 Query: 119 SYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIAESVEGLPVGLLINNVGAAYPS--PDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFLN 862 S G W VVTG ++GIG+ + LA+R N++++SR + L ++E+ V+ I ADF I+ I E ++ L VG+L+NNVG PS P + D+ +++CN + V M R++L ++ GVI+N+SS + + P+ T+YA+ K + F+ LQAE + +G I +Q PF V ++++G + + E+F + L+ L +++ G I H W L + K L+ Sbjct: 49 SMGEWAVVTGASEGIGRAYAFALAERGMNIVIMSRTKSTLDQVAKEISNSTGQKVRVIIADFTDENIFSEIEEQLKDLCVGILVNNVG-ILPSFIPYRFLESEDLDQTITKVINCNVKTMVKMCRMILPQMDKRRKGVIVNISSGIASVPFPLYTLYAASKIFVERFSQGLQAEYENRG----ILIQAVAPFGVCTRMAGYQPPNRVTFLPEDFVKNSLQYLRAGNKTHGSICHIVLGWILQCIPLKVLH 293
BLAST of SMED30021475 vs. Planmine SMEST
Match: SMESG000062708.1 (SMESG000062708.1) HSP 1 Score: 625.55 bits (1612), Expect = 0.000e+0 Identity = 319/324 (98.46%), Postives = 321/324 (99.07%), Query Frame = -3 Query: 44 NCLVYLDYNLILYLCLIXXXXXXXXXXXXXXXVLWTYKLKPVSESKFDKIKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFLNKVLVRRSMMKLRDQASRKRDKIKNL 1015 N LVYLDYNLILYLCLI CVSF+FYHVVYFAAVLWTYKLKPVSESKFDKIKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIA SVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVI+NMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFLNKVLVRRSMMKLRDQASRKRDKIKNL Sbjct: 4 NFLVYLDYNLILYLCLIACVSFIFYHVVYFAAVLWTYKLKPVSESKFDKIKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIAASVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIVNMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFLNKVLVRRSMMKLRDQASRKRDKIKNL 327
BLAST of SMED30021475 vs. Planmine SMEST
Match: SMESG000077527.1 (SMESG000077527.1) HSP 1 Score: 224.557 bits (571), Expect = 3.039e-71 Identity = 122/281 (43.42%), Postives = 171/281 (60.85%), Query Frame = -3 Query: 53 PVSESKFDKIKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKLSGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFLNKVLVRRSMMKLRDQASRKRDKI 895 P S +I YGNWVVVTG TDGIGK F E LAK KFNL+LISR+ EKL E++EK + ++ I+ADF K IYD I ++ L +GLLINNVG + PD+ T++ S I++L+CNCLSTVLMTR+LLK M +GG I+N+SSASS IP L++Y S K+ +N FT + +E +++ QN PF+V +K+S ++ PT + +S L +L + ++G H + WF+ L+P F+ + LV R +A RK KI Sbjct: 39 PFVFSSRQEINKYGNWVVVTGATDGIGKAFAELLAKDKFNLVLISRSFEKLEKVKNEILEKHNVDIRIISADFSKLDIYDKIESEIKDLEIGLLINNVGMSSKYPDYLTSEINSPDSVINILNCNCLSTVLMTRLLLKIRMADKGGFILNVSSASSMFPIPFLSVYGSSKAFINSFTRSMISEFR-----NKVHFQNVAPFFVSTKMSKLRP-SLTAPTPRNYANSVLNRLGTSTFTYGCFVHELQGWFIG-LLPSFVIEKLVYNVNYGTRIRAIRKATKI 312
BLAST of SMED30021475 vs. Planmine SMEST
Match: SMESG000075064.1 (SMESG000075064.1) HSP 1 Score: 147.517 bits (371), Expect = 1.014e-41 Identity = 105/287 (36.59%), Postives = 161/287 (56.10%), Query Frame = -3 Query: 80 LWTYKLKPVSESKFDKIKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIAESVEGLPVGLLINNVGAAYPSP-DFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKL-SGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFLN----KVLVR--RSMMKLRD 916 ++ YK S IK G W VVTG TDGIG+ +C +LAK N+ LISR+E+KL I S+EL + ++I V Y ADF IY+ + E ++GL +G+L+NNVG P DF D +++ N LS V+M++I+ ++ G+IIN+SSASS +P+ +Y++ KS L F+ L E+ G I VQ PF+V +KL + + KF + EEF +S +R + +FG + HS + + IP F++ K++ R +S +KLR+ Sbjct: 25 IFKYKFLLQSNKHVKLIKESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGIQQPFVCDFIDIDE--SFSLSGIININILSAVMMSKIISAEMSQRKRGIIINISSASSLSPLPMAAIYSATKSFLTHFSLALNEELSKYG----ILVQTVRPFFVQTKLIAAYRLPKFFMSPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRS-IPLFISIKIGKMIFRYFQSGLKLRE 304
BLAST of SMED30021475 vs. Planmine SMEST
Match: SMESG000075064.1 (SMESG000075064.1) HSP 1 Score: 147.517 bits (371), Expect = 1.077e-41 Identity = 105/287 (36.59%), Postives = 161/287 (56.10%), Query Frame = -3 Query: 80 LWTYKLKPVSESKFDKIKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIAESVEGLPVGLLINNVGAAYPSP-DFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKL-SGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFLN----KVLVR--RSMMKLRD 916 ++ YK S IK G W VVTG TDGIG+ +C +LAK N+ LISR+E+KL I S+EL + ++I V Y ADF IY+ + E ++GL +G+L+NNVG P DF D +++ N LS V+M++I+ ++ G+IIN+SSASS +P+ +Y++ KS L F+ L E+ G I VQ PF+V +KL + + KF + EEF +S +R + +FG + HS + + IP F++ K++ R +S +KLR+ Sbjct: 24 IFKYKFLLQSNKHVKLIKESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGIQQPFVCDFIDIDE--SFSLSGIININILSAVMMSKIISAEMSQRKRGIIINISSASSLSPLPMAAIYSATKSFLTHFSLALNEELSKYG----ILVQTVRPFFVQTKLIAAYRLPKFFMSPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRS-IPLFISIKIGKMIFRYFQSGLKLRE 303
BLAST of SMED30021475 vs. Planmine SMEST
Match: SMESG000079254.1 (SMESG000079254.1) HSP 1 Score: 54.6842 bits (130), Expect = 2.127e-8 Identity = 53/198 (26.77%), Postives = 92/198 (46.46%), Query Frame = -3 Query: 275 VVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKL-----LIQSQELMEKFRISVKYITADFRKTKIYDHIAES--VEGLPVGLLINNVGAAYPSPDFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIINMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKL 847 ++TG + GIGK E K N+++ RN E L L + ++ E RI TAD + +AE +E + +LINN G S D T +++ +F +++ N S + +T LL ++ + G I+N+SS + P + Y K+ L FT C ++ ++G + V +P ++ L Sbjct: 12 ALITGASSGIGKSTAELFFKLGANILITGRNLENLNDTIKLCELSKVNENQRIVA--FTADLTNEEDVKKLAEKTLLEFPKLDILINNAGVI--SND--TIENVEMENFDSVMNMNLRSVIQLTN-LLSPSLIDRKGSIVNVSSVAGTRAFPNVMSYCISKAALEQFTKCTALDLASKG----VRVNAVSPGVTVTNL 198 The following BLAST results are available for this feature:
BLAST of SMED30021475 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of SMED30021475 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of SMED30021475 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of SMED30021475 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of SMED30021475 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of SMED30021475 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of SMED30021475 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of SMED30021475 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of SMED30021475 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of SMED30021475 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of SMED30021475 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 2
BLAST of SMED30021475 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of SMED30021475 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of SMED30021475 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30021475 ID=SMED30021475|Name=SMED30021475|organism=Schmidtea mediterranea sexual|type=transcript|length=1020bpback to top protein sequence of SMED30021475-orf-1 >SMED30021475-orf-1 ID=SMED30021475-orf-1|Name=SMED30021475-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=227bp MEKFRISVKYITADFRKTKIYDHIAESVEGLPVGLLINNVGAAYPSPDFYback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
|