cAMP-dependent protein kinase catalytic subunit

Overview
NamecAMP-dependent protein kinase catalytic subunit
Smed IDSMED30021427
Length (bp)1253
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of cAMP-dependent protein kinase catalytic subunit (SMED30021427) t-SNE clustered cells

Violin plots show distribution of expression levels for cAMP-dependent protein kinase catalytic subunit (SMED30021427) in cells (dots) of each of the 12 neoblast clusters.

 

back to top


 

Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020




SMED30021427

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 1

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
testis primordiumSMED30021427SMESG000051702.1 Contig6761_SE3GPL10652PMID:20844018
Wang et al., 2010
whole organism juvenile cDNA to DNA expression microarray evidence
Note: Hover over icons to view figure legend
Homology
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Human
Match: PRKACB (protein kinase cAMP-activated catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:9381])

HSP 1 Score: 267.314 bits (682), Expect = 2.467e-85
Identity = 147/350 (42.00%), Postives = 214/350 (61.14%), Query Frame = 3
Query:   99 SDFPGMWDKLTWEFLGRLKE-------NPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPFPIK---NPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            S+   +WD+   EFL + KE       NP       +DFE  + LG G FGRV+L +HK+   Y A+KI++K+K++K+KQI   + EK IL    F FL+RL   F+ N N+   +E  PGG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI + GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ PF  K   + D S    D+  EE    S+T K  +EF  F
Sbjct:   53 SEHTALWDRSMKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNF--DDYEEEDIRVSITEKCAKEFGEF 398          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Human
Match: PRKACB (protein kinase cAMP-activated catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:9381])

HSP 1 Score: 260.381 bits (664), Expect = 3.255e-83
Identity = 145/343 (42.27%), Postives = 209/343 (60.93%), Query Frame = 3
Query:  120 DKLTWEFLGRLKE-------NPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPFPIK---NPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            D    EFL + KE       NP       +DFE  + LG G FGRV+L +HK+   Y A+KI++K+K++K+KQI   + EK IL    F FL+RL   F+ N N+   +E  PGG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI + GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ PF  K   + D S    D+  EE    S+T K  +EF  F
Sbjct:   19 DSFVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNF--DDYEEEDIRVSITEKCAKEFGEF 357          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Human
Match: PRKACB (protein kinase cAMP-activated catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:9381])

HSP 1 Score: 260.381 bits (664), Expect = 3.902e-83
Identity = 145/343 (42.27%), Postives = 209/343 (60.93%), Query Frame = 3
Query:  120 DKLTWEFLGRLKE-------NPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPFPIK---NPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            D    EFL + KE       NP       +DFE  + LG G FGRV+L +HK+   Y A+KI++K+K++K+KQI   + EK IL    F FL+RL   F+ N N+   +E  PGG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI + GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ PF  K   + D S    D+  EE    S+T K  +EF  F
Sbjct:   20 DSFVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNF--DDYEEEDIRVSITEKCAKEFGEF 358          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Human
Match: PRKACB (protein kinase cAMP-activated catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:9381])

HSP 1 Score: 259.61 bits (662), Expect = 6.155e-83
Identity = 144/338 (42.60%), Postives = 208/338 (61.54%), Query Frame = 3
Query:  135 EFLGRLKE-------NPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPFPIK---NPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            EFL + KE       NP       +DFE  + LG G FGRV+L +HK+   Y A+KI++K+K++K+KQI   + EK IL    F FL+RL   F+ N N+   +E  PGG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI + GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ PF  K   + D S    D+  EE    S+T K  +EF  F
Sbjct:   18 EFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNF--DDYEEEDIRVSITEKCAKEFGEF 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Human
Match: PRKACB (protein kinase cAMP-activated catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:9381])

HSP 1 Score: 258.84 bits (660), Expect = 7.387e-83
Identity = 144/338 (42.60%), Postives = 208/338 (61.54%), Query Frame = 3
Query:  135 EFLGRLKE-------NPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPFPIK---NPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            EFL + KE       NP       +DFE  + LG G FGRV+L +HK+   Y A+KI++K+K++K+KQI   + EK IL    F FL+RL   F+ N N+   +E  PGG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI + GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ PF  K   + D S    D+  EE    S+T K  +EF  F
Sbjct:    6 EFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNF--DDYEEEDIRVSITEKCAKEFGEF 339          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Celegans
Match: kin-1 (cAMP-dependent protein kinase catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P21137])

HSP 1 Score: 258.455 bits (659), Expect = 2.000e-82
Identity = 145/341 (42.52%), Postives = 208/341 (61.00%), Query Frame = 3
Query:  102 DFPGMWDKLTWEFLGRLKENPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            DF    DK   +F  R  ENP       DDF+ I+ LG G FGRV+L +HK    Y A+KI++K+K++K+KQ+   + EK IL    F FL+ +  +F+ N N+   LE   GG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI + GY+K+ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK K P   S E K L+K LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ PF    + P  +    D + E +R  S T K  +EF  F
Sbjct:   52 DFKEFLDKAREDFKQRW-ENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKIEAPFLPKCRGPGDASNFDDYEEEPLR-ISGTEKCAKEFAEF 388          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Celegans
Match: kin-1 (cAMP-dependent protein kinase catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P21137])

HSP 1 Score: 258.455 bits (659), Expect = 2.464e-82
Identity = 135/304 (44.41%), Postives = 192/304 (63.16%), Query Frame = 3
Query:   99 SDFPGMWDKLTWEFLGRLKENPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPP 1010
             DF    DK   +F  R  ENP       DDF+ I+ LG G FGRV+L +HK    Y A+KI++K+K++K+KQ+   + EK IL    F FL+ +  +F+ N N+   LE   GG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI + GY+K+ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK K P   S E K L+K LLQ+D TKR GNL+NG  D++ H +F   DW  +  + + PP
Sbjct:   51 EDFKEFLDKAREDFKQRW-ENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKITPP 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Celegans
Match: kin-1 (cAMP-dependent protein kinase catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P21137])

HSP 1 Score: 256.529 bits (654), Expect = 3.274e-82
Identity = 144/340 (42.35%), Postives = 207/340 (60.88%), Query Frame = 3
Query:  105 FPGMWDKLTWEFLGRLKENPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            F    DK   +F  R  ENP       DDF+ I+ LG G FGRV+L +HK    Y A+KI++K+K++K+KQ+   + EK IL    F FL+ +  +F+ N N+   LE   GG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI + GY+K+ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK K P   S E K L+K LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ PF    + P  +    D + E +R  S T K  +EF  F
Sbjct:   14 FKEFLDKAREDFKQRW-ENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKIEAPFLPKCRGPGDASNFDDYEEEPLR-ISGTEKCAKEFAEF 349          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Celegans
Match: kin-1 (cAMP-dependent protein kinase catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P21137])

HSP 1 Score: 256.529 bits (654), Expect = 4.974e-82
Identity = 134/302 (44.37%), Postives = 191/302 (63.25%), Query Frame = 3
Query:  105 FPGMWDKLTWEFLGRLKENPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPP 1010
            F    DK   +F  R  ENP       DDF+ I+ LG G FGRV+L +HK    Y A+KI++K+K++K+KQ+   + EK IL    F FL+ +  +F+ N N+   LE   GG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI + GY+K+ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK K P   S E K L+K LLQ+D TKR GNL+NG  D++ H +F   DW  +  + + PP
Sbjct:   14 FKEFLDKAREDFKQRW-ENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKITPP 312          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Celegans
Match: kin-1 (cAMP-dependent protein kinase catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P21137])

HSP 1 Score: 256.914 bits (655), Expect = 5.066e-82
Identity = 133/297 (44.78%), Postives = 190/297 (63.97%), Query Frame = 3
Query:  120 DKLTWEFLGRLKENPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPP 1010
            DK   +F  R  ENP       DDF+ I+ LG G FGRV+L +HK    Y A+KI++K+K++K+KQ+   + EK IL    F FL+ +  +F+ N N+   LE   GG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI + GY+K+ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK K P   S E K L+K LLQ+D TKR GNL+NG  D++ H +F   DW  +  + + PP
Sbjct:   29 DKAREDFKQRW-ENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKITPP 322          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Fly
Match: Pka-C1 (gene:FBgn0000273 transcript:FBtr0335495)

HSP 1 Score: 247.669 bits (631), Expect = 1.180e-78
Identity = 137/330 (41.52%), Postives = 203/330 (61.52%), Query Frame = 3
Query:  135 EFLGRLKENPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            EF  + + NP +   A DDFE I+ LG G FGRV++ +HK    Y A+KI++K+K++K+KQ+   + EK IL   +F FL+ L   F+ N N+   LE  PGG+++  ++    F     RFY++Q++L  +YLH + ++YRDLKPEN+LI + GY+K+ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVL+YE+     PF+    I+I+  IV GK + P     + K L++ LLQ+D TKR GNL+ G  D++   +F   DW  +  + ++ PF    K P  +    D + E +R  S T K  +EF  F
Sbjct:   28 EFEDKWRRNPTN-TAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPRCKGPGDTSNFDDYEEEALRISS-TEKCAKEFAEF 353          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Fly
Match: Pka-C1 (gene:FBgn0000273 transcript:FBtr0079852)

HSP 1 Score: 247.669 bits (631), Expect = 1.180e-78
Identity = 137/330 (41.52%), Postives = 203/330 (61.52%), Query Frame = 3
Query:  135 EFLGRLKENPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            EF  + + NP +   A DDFE I+ LG G FGRV++ +HK    Y A+KI++K+K++K+KQ+   + EK IL   +F FL+ L   F+ N N+   LE  PGG+++  ++    F     RFY++Q++L  +YLH + ++YRDLKPEN+LI + GY+K+ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVL+YE+     PF+    I+I+  IV GK + P     + K L++ LLQ+D TKR GNL+ G  D++   +F   DW  +  + ++ PF    K P  +    D + E +R  S T K  +EF  F
Sbjct:   28 EFEDKWRRNPTN-TAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPRCKGPGDTSNFDDYEEEALRISS-TEKCAKEFAEF 353          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Fly
Match: Pka-C1 (gene:FBgn0000273 transcript:FBtr0079851)

HSP 1 Score: 247.669 bits (631), Expect = 1.180e-78
Identity = 137/330 (41.52%), Postives = 203/330 (61.52%), Query Frame = 3
Query:  135 EFLGRLKENPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            EF  + + NP +   A DDFE I+ LG G FGRV++ +HK    Y A+KI++K+K++K+KQ+   + EK IL   +F FL+ L   F+ N N+   LE  PGG+++  ++    F     RFY++Q++L  +YLH + ++YRDLKPEN+LI + GY+K+ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVL+YE+     PF+    I+I+  IV GK + P     + K L++ LLQ+D TKR GNL+ G  D++   +F   DW  +  + ++ PF    K P  +    D + E +R  S T K  +EF  F
Sbjct:   28 EFEDKWRRNPTN-TAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPRCKGPGDTSNFDDYEEEALRISS-TEKCAKEFAEF 353          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Fly
Match: CG12069 (gene:FBgn0039796 transcript:FBtr0085728)

HSP 1 Score: 231.106 bits (588), Expect = 3.989e-72
Identity = 131/344 (38.08%), Postives = 203/344 (59.01%), Query Frame = 3
Query:  102 DFPGMWDKLTWEFLGRLKENPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPF--YYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNP-DYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            D+  + DKL  +F  +   N     T  DD+E    LG G FG+V L R +   +Y A K + K++I+K KQ+  V+ EK +L    F   + L  +++  D++   L L  GG+L+   +    F  +  RFY++QV L L+YLH   ++YRDLKPENI++  NGY+K+ D GFAK ++   RT T CGTPEY+ PE++ +K YGT+VDWWAFGVL++E     +PF  +  D + ++  I +  YK+P   S   + L+ +LLQ+D +KR GNL NG  D++ H +FK ++W  ++ Q +  P+   I NP D S    D+  ++ R K+ T+++ E F +F
Sbjct:   17 DYILILDKLREDFNKKFATNTPSPSTGLDDYEIKATLGSGSFGKVQLVRERESGVYYASKQLSKDQIVKTKQVSHVMSEKNVLRSMTFPNTVNLIASYKDFDSLYLVLPLIGGGELFTYHRKVRKFTEKQARFYAAQVFLALEYLHHCSLLYRDLKPENIMMDKNGYLKVTDFGFAKKVET--RTMTLCGTPEYLPPEIIQSKPYGTSVDWWAFGVLVFEFVAGHSPFSAHNRDVMSMYNKICEADYKMPSYFSGALRHLVDHLLQVDLSKRFGNLINGNRDIKEHEWFKDVEWIPLLNQTVNAPYVPNISNPEDISNF--DKVSDKPRPKAKTMRHEEAFADF 356          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Fly
Match: CG12069 (gene:FBgn0039796 transcript:FBtr0335455)

HSP 1 Score: 231.106 bits (588), Expect = 3.989e-72
Identity = 131/344 (38.08%), Postives = 203/344 (59.01%), Query Frame = 3
Query:  102 DFPGMWDKLTWEFLGRLKENPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPF--YYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNP-DYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            D+  + DKL  +F  +   N     T  DD+E    LG G FG+V L R +   +Y A K + K++I+K KQ+  V+ EK +L    F   + L  +++  D++   L L  GG+L+   +    F  +  RFY++QV L L+YLH   ++YRDLKPENI++  NGY+K+ D GFAK ++   RT T CGTPEY+ PE++ +K YGT+VDWWAFGVL++E     +PF  +  D + ++  I +  YK+P   S   + L+ +LLQ+D +KR GNL NG  D++ H +FK ++W  ++ Q +  P+   I NP D S    D+  ++ R K+ T+++ E F +F
Sbjct:   17 DYILILDKLREDFNKKFATNTPSPSTGLDDYEIKATLGSGSFGKVQLVRERESGVYYASKQLSKDQIVKTKQVSHVMSEKNVLRSMTFPNTVNLIASYKDFDSLYLVLPLIGGGELFTYHRKVRKFTEKQARFYAAQVFLALEYLHHCSLLYRDLKPENIMMDKNGYLKVTDFGFAKKVET--RTMTLCGTPEYLPPEIIQSKPYGTSVDWWAFGVLVFEFVAGHSPFSAHNRDVMSMYNKICEADYKMPSYFSGALRHLVDHLLQVDLSKRFGNLINGNRDIKEHEWFKDVEWIPLLNQTVNAPYVPNISNPEDISNF--DKVSDKPRPKAKTMRHEEAFADF 356          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Match: prkacbb (protein kinase, cAMP-dependent, catalytic, beta b [Source:ZFIN;Acc:ZDB-GENE-050904-4])

HSP 1 Score: 261.922 bits (668), Expect = 4.244e-84
Identity = 141/337 (41.84%), Postives = 211/337 (62.61%), Query Frame = 3
Query:  135 EFLGRLKEN-------PVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            EFL + KE+       P    T  DDF+  + LG G FGRV+L +HK+ + Y A+K+++K+K++K+KQ+   + EK IL    F FL+RL   F+ N N+   +E  PGG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI  +GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNLRNG  D++ H +F   DW  +  + ++ PF    + P  +    D + E++R  S+T K  +EF  F
Sbjct:   18 EFLAKAKEDFLRKWESPQQSTTCLDDFDRQKTLGTGSFGRVLLVKHKASDQYYAMKVLDKQKVVKLKQVEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLRNGVNDIKNHKWFATTDWIAIYERKVEAPFIPKCRGPGDTSNFDDYEEEDIR-VSVTEKCAKEFSEF 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Match: prkacaa (protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a [Source:ZFIN;Acc:ZDB-GENE-050114-6])

HSP 1 Score: 261.151 bits (666), Expect = 1.071e-83
Identity = 143/337 (42.43%), Postives = 208/337 (61.72%), Query Frame = 3
Query:  135 EFLGRLKE-------NPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            EFL + KE       NP     + D FE ++ LG G FGRV+L +HK    + A+KI++K+K++K+KQI   + EK IL    F FL+RL  +F+ N N+   +E  PGG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI   GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ PF    K P  +    D   EE+R  S+T K  +EF  F
Sbjct:   19 EFLAKAKEDFLKKWENPAQNTASLDHFERLKTLGTGSFGRVMLVKHKESGQHFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEHSFKDNTNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKGHKWFATTDWIAIYQKKVEAPFIPKCKGPGDTSNFDDYDEEEIR-VSITEKCGKEFAEF 352          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Match: prkacab (protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b [Source:ZFIN;Acc:ZDB-GENE-040801-208])

HSP 1 Score: 253.062 bits (645), Expect = 1.502e-80
Identity = 135/323 (41.80%), Postives = 200/323 (61.92%), Query Frame = 3
Query:  156 ENPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            ENP       +DF+ ++ LG G FGRV+L RH+    + A+KI+ K+K++K+KQI   + EK IL    F FL+RL  +F+ N N+   ++   GG+++  ++    F     RFY+SQ++L  +YLH + ++YRDLKPEN+LI   GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVL+YE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ PF    + P  +    D + EE+R  S T K  +EF  F
Sbjct:   32 ENPAQNTACLEDFDRLKTLGTGSFGRVMLVRHRETGQHYAMKILNKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYSFKDNTNLYMVMQYVQGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLMYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKGHKWFSTTDWIAIYQRRVEAPFVPKCRGPGDTSNFDDYEEEEIR-VSFTEKCAKEFAEF 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Match: prkacba (protein kinase, cAMP-dependent, catalytic, beta a [Source:ZFIN;Acc:ZDB-GENE-040426-1351])

HSP 1 Score: 248.44 bits (633), Expect = 3.096e-78
Identity = 140/350 (40.00%), Postives = 211/350 (60.29%), Query Frame = 3
Query:   99 SDFPGMWDKLTWEFLGRLKENPVDR-------KTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNP-DYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            S+   +WD    E L + KE+ +++           DDF+ ++ LG G FGRV+L +HK    Y A+KI++K K++K+KQI   + EK IL    F FL++L   F+ N N+   +    GG+++  ++    F  Q  RFY++Q++L  +YLH + ++YRDLKPEN+LI + GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + +  P     + P D S    DE  EE+   S++ +  +EF +F
Sbjct:   50 SEHTVLWDTAMKETLAKAKEDFLNKWECQQKSTACLDDFDKLKTLGTGSFGRVMLVKHKQSEQYFAMKILDKLKVVKLKQIEHTLNEKKILQAVSFPFLVKLECAFKDNSNLYMVMRYIQGGEMFSHLRRIGRFSEQNARFYAAQIVLTFEYLHMLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRYPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKNHRWFASTDWIAIYEKKVDAPIIPKCRGPGDTSNF--DEYDEEVIRVSVSEQCSKEFLDF 395          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Match: prkacba (protein kinase, cAMP-dependent, catalytic, beta a [Source:ZFIN;Acc:ZDB-GENE-040426-1351])

HSP 1 Score: 248.44 bits (633), Expect = 3.096e-78
Identity = 140/350 (40.00%), Postives = 211/350 (60.29%), Query Frame = 3
Query:   99 SDFPGMWDKLTWEFLGRLKENPVDR-------KTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNP-DYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            S+   +WD    E L + KE+ +++           DDF+ ++ LG G FGRV+L +HK    Y A+KI++K K++K+KQI   + EK IL    F FL++L   F+ N N+   +    GG+++  ++    F  Q  RFY++Q++L  +YLH + ++YRDLKPEN+LI + GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + +  P     + P D S    DE  EE+   S++ +  +EF +F
Sbjct:   50 SEHTVLWDTAMKETLAKAKEDFLNKWECQQKSTACLDDFDKLKTLGTGSFGRVMLVKHKQSEQYFAMKILDKLKVVKLKQIEHTLNEKKILQAVSFPFLVKLECAFKDNSNLYMVMRYIQGGEMFSHLRRIGRFSEQNARFYAAQIVLTFEYLHMLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRYPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKNHRWFASTDWIAIYEKKVDAPIIPKCRGPGDTSNF--DEYDEEVIRVSVSEQCSKEFLDF 395          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Match: prkacb (protein kinase cAMP-activated catalytic subunit beta [Source:NCBI gene;Acc:100038053])

HSP 1 Score: 263.462 bits (672), Expect = 1.826e-84
Identity = 144/337 (42.73%), Postives = 211/337 (62.61%), Query Frame = 3
Query:  135 EFLGRLKEN-------PVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            EFL + KE+       P     + DDFE I+ LG G FGRV+L +HK    Y A+KI++K+K++K+KQI   + EK IL    F FL+RL  +F+ N N+   +E  PGG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI   GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ PF    + P  +    D + E++R  SLT K  +EF +F
Sbjct:   18 EFLAKAKEDFLRKWETPPQNTASLDDFERIKTLGTGSFGRVMLVKHKGAEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKCRGPGDTSNFDDYEEEDIR-VSLTEKCAKEFADF 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Match: ints8 (integrator complex subunit 8 [Source:Xenbase;Acc:XB-GENE-980129])

HSP 1 Score: 263.462 bits (672), Expect = 3.955e-84
Identity = 145/343 (42.27%), Postives = 210/343 (61.22%), Query Frame = 3
Query:  117 WDKLTWEFLGRLKE-------NPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            W++   EFL + KE       NP       + FE I+ LG G FGRV+L RHK    + A+KI++K+K++K+KQI   + EK IL    F FL+RL  +F+ N N+   +E   GG+++  ++    F     RFY+SQ++L  +YLH + ++YRDLKPEN+LI   GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ PF    K P  +    D + EE+R  S+T K  +EF +F
Sbjct:   44 WEREMKEFLAKAKEDFLKKWENPAQNTAHLEQFERIKTLGTGSFGRVMLVRHKENGSHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVTDIKGHKWFSTTDWIAVYQKKVEAPFIPKCKGPGDTSNFDDYEEEEIR-VSITEKCAKEFSDF 383          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Match: ints8 (integrator complex subunit 8 [Source:Xenbase;Acc:XB-GENE-980129])

HSP 1 Score: 261.151 bits (666), Expect = 1.180e-83
Identity = 144/337 (42.73%), Postives = 207/337 (61.42%), Query Frame = 3
Query:  135 EFLGRLKE-------NPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            EFL + KE       NP       + FE I+ LG G FGRV+L RHK    + A+KI++K+K++K+KQI   + EK IL    F FL+RL  +F+ N N+   +E   GG+++  ++    F     RFY+SQ++L  +YLH + ++YRDLKPEN+LI   GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ PF    K P  +    D + EE+R  S+T K  +EF +F
Sbjct:   18 EFLAKAKEDFLKKWENPAQNTAHLEQFERIKTLGTGSFGRVMLVRHKENGSHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVTDIKGHKWFSTTDWIAVYQKKVEAPFIPKCKGPGDTSNFDDYEEEEIR-VSITEKCAKEFSDF 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Match: ints8 (integrator complex subunit 8 [Source:Xenbase;Acc:XB-GENE-980129])

HSP 1 Score: 260.766 bits (665), Expect = 1.261e-83
Identity = 144/337 (42.73%), Postives = 207/337 (61.42%), Query Frame = 3
Query:  135 EFLGRLKE-------NPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            EFL + KE       NP       + FE I+ LG G FGRV+L RHK    + A+KI++K+K++K+KQI   + EK IL    F FL+RL  +F+ N N+   +E   GG+++  ++    F     RFY+SQ++L  +YLH + ++YRDLKPEN+LI   GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ PF    K P  +    D + EE+R  S+T K  +EF +F
Sbjct:    4 EFLAKAKEDFLKKWENPAQNTAHLEQFERIKTLGTGSFGRVMLVRHKENGSHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVTDIKGHKWFSTTDWIAVYQKKVEAPFIPKCKGPGDTSNFDDYEEEEIR-VSITEKCAKEFSDF 337          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Match: ints8 (integrator complex subunit 8 [Source:Xenbase;Acc:XB-GENE-980129])

HSP 1 Score: 260.766 bits (665), Expect = 1.317e-83
Identity = 144/337 (42.73%), Postives = 207/337 (61.42%), Query Frame = 3
Query:  135 EFLGRLKE-------NPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            EFL + KE       NP       + FE I+ LG G FGRV+L RHK    + A+KI++K+K++K+KQI   + EK IL    F FL+RL  +F+ N N+   +E   GG+++  ++    F     RFY+SQ++L  +YLH + ++YRDLKPEN+LI   GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ PF    K P  +    D + EE+R  S+T K  +EF +F
Sbjct:    4 EFLAKAKEDFLKKWENPAQNTAHLEQFERIKTLGTGSFGRVMLVRHKENGSHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVTDIKGHKWFSTTDWIAVYQKKVEAPFIPKCKGPGDTSNFDDYEEEEIR-VSITEKCAKEFSDF 337          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Mouse
Match: Prkacb (protein kinase, cAMP dependent, catalytic, beta [Source:MGI Symbol;Acc:MGI:97594])

HSP 1 Score: 266.159 bits (679), Expect = 4.417e-85
Identity = 149/350 (42.57%), Postives = 217/350 (62.00%), Query Frame = 3
Query:   99 SDFPGMWDKLTWEFLGRLKE-------NPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPFPIK---NPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            S+    WDK   EFL + KE       NP       +DFE  + LG G FGRV+L +HK+   Y A+KI++K+K++K+KQI   + EK IL   +F FL+RL  +F+ N N+   +E  PGG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI + GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ PF  K   + D S    D + EE+R  S+T K  +EF  F
Sbjct:   53 SEHTASWDKSMKEFLAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNF-DDYEEEEIR-VSITEKCGKEFCEF 398          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Mouse
Match: Prkacb (protein kinase, cAMP dependent, catalytic, beta [Source:MGI Symbol;Acc:MGI:97594])

HSP 1 Score: 257.684 bits (657), Expect = 1.271e-82
Identity = 145/338 (42.90%), Postives = 212/338 (62.72%), Query Frame = 3
Query:  135 EFLGRLKE-------NPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPFPIK---NPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            EFL + KE       NP       +DFE  + LG G FGRV+L +HK+   Y A+KI++K+K++K+KQI   + EK IL   +F FL+RL  +F+ N N+   +E  PGG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI + GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ PF  K   + D S    D + EE+R  S+T K  +EF  F
Sbjct:    5 EFLAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNF-DDYEEEEIR-VSITEKCGKEFCEF 338          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Mouse
Match: Prkacb (protein kinase, cAMP dependent, catalytic, beta [Source:MGI Symbol;Acc:MGI:97594])

HSP 1 Score: 258.07 bits (658), Expect = 1.311e-82
Identity = 145/338 (42.90%), Postives = 212/338 (62.72%), Query Frame = 3
Query:  135 EFLGRLKE-------NPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPFPIK---NPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            EFL + KE       NP       +DFE  + LG G FGRV+L +HK+   Y A+KI++K+K++K+KQI   + EK IL   +F FL+RL  +F+ N N+   +E  PGG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI + GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ PF  K   + D S    D + EE+R  S+T K  +EF  F
Sbjct:   18 EFLAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNF-DDYEEEEIR-VSITEKCGKEFCEF 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Mouse
Match: Prkacb (protein kinase, cAMP dependent, catalytic, beta [Source:MGI Symbol;Acc:MGI:97594])

HSP 1 Score: 257.684 bits (657), Expect = 1.557e-82
Identity = 145/338 (42.90%), Postives = 212/338 (62.72%), Query Frame = 3
Query:  135 EFLGRLKE-------NPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPFPIK---NPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            EFL + KE       NP       +DFE  + LG G FGRV+L +HK+   Y A+KI++K+K++K+KQI   + EK IL   +F FL+RL  +F+ N N+   +E  PGG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI + GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ PF  K   + D S    D + EE+R  S+T K  +EF  F
Sbjct:    6 EFLAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNF-DDYEEEEIR-VSITEKCGKEFCEF 339          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Mouse
Match: Prkaca (protein kinase, cAMP dependent, catalytic, alpha [Source:MGI Symbol;Acc:MGI:97592])

HSP 1 Score: 251.521 bits (641), Expect = 3.737e-80
Identity = 139/337 (41.25%), Postives = 206/337 (61.13%), Query Frame = 3
Query:  135 EFLGRLKEN-------PVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            EFL + KE+       P       D F+ I+ LG G FGRV+L +HK    + A+KI++K+K++K+KQI   + EK IL    F FL++L  +F+ N N+   +E   GG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI   GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ PF    K P  +    D + EE+R  S+  K  +EF  F
Sbjct:   10 EFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIR-VSINEKCGKEFTEF 343          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Match: sp|P22694|KAPCB_HUMAN (cAMP-dependent protein kinase catalytic subunit beta OS=Homo sapiens OX=9606 GN=PRKACB PE=1 SV=2)

HSP 1 Score: 259.61 bits (662), Expect = 2.956e-82
Identity = 144/338 (42.60%), Postives = 208/338 (61.54%), Query Frame = 3
Query:  135 EFLGRLKE-------NPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPFPIK---NPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            EFL + KE       NP       +DFE  + LG G FGRV+L +HK+   Y A+KI++K+K++K+KQI   + EK IL    F FL+RL   F+ N N+   +E  PGG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI + GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ PF  K   + D S    D+  EE    S+T K  +EF  F
Sbjct:   18 EFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNF--DDYEEEDIRVSITEKCAKEFGEF 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Match: sp|P36887|KAPCA_PIG (cAMP-dependent protein kinase catalytic subunit alpha OS=Sus scrofa OX=9823 GN=PRKACA PE=1 SV=4)

HSP 1 Score: 258.84 bits (660), Expect = 4.906e-82
Identity = 142/337 (42.14%), Postives = 207/337 (61.42%), Query Frame = 3
Query:  135 EFLGRLKE-------NPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            EFL + KE       NP       D FE I+ LG G FGRV+L +HK    + A+KI++K+K++K+KQI   + EK IL    F FL++L  +F+ N N+   +E  PGG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI   GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ PF    K P  +    D + EE+R  S+  K  +EF  F
Sbjct:   18 EFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIR-VSINEKCGKEFSEF 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Match: sp|P68182|KAPCB_RAT (cAMP-dependent protein kinase catalytic subunit beta OS=Rattus norvegicus OX=10116 GN=Prkacb PE=1 SV=2)

HSP 1 Score: 258.07 bits (658), Expect = 9.170e-82
Identity = 145/338 (42.90%), Postives = 212/338 (62.72%), Query Frame = 3
Query:  135 EFLGRLKE-------NPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPFPIK---NPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            EFL + KE       NP       +DFE  + LG G FGRV+L +HK+   Y A+KI++K+K++K+KQI   + EK IL   +F FL+RL  +F+ N N+   +E  PGG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI + GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ PF  K   + D S    D + EE+R  S+T K  +EF  F
Sbjct:   18 EFLAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNF-DDYEEEEIR-VSITEKCGKEFCEF 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Match: sp|P68181|KAPCB_MOUSE (cAMP-dependent protein kinase catalytic subunit beta OS=Mus musculus OX=10090 GN=Prkacb PE=1 SV=2)

HSP 1 Score: 258.07 bits (658), Expect = 9.170e-82
Identity = 145/338 (42.90%), Postives = 212/338 (62.72%), Query Frame = 3
Query:  135 EFLGRLKE-------NPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPFPIK---NPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            EFL + KE       NP       +DFE  + LG G FGRV+L +HK+   Y A+KI++K+K++K+KQI   + EK IL   +F FL+RL  +F+ N N+   +E  PGG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI + GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ PF  K   + D S    D + EE+R  S+T K  +EF  F
Sbjct:   18 EFLAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNF-DDYEEEEIR-VSITEKCGKEFCEF 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Match: sp|P68180|KAPCB_CRIGR (cAMP-dependent protein kinase catalytic subunit beta OS=Cricetulus griseus OX=10029 GN=PRKACB PE=2 SV=2)

HSP 1 Score: 258.07 bits (658), Expect = 9.170e-82
Identity = 145/338 (42.90%), Postives = 212/338 (62.72%), Query Frame = 3
Query:  135 EFLGRLKE-------NPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPFPIK---NPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            EFL + KE       NP       +DFE  + LG G FGRV+L +HK+   Y A+KI++K+K++K+KQI   + EK IL   +F FL+RL  +F+ N N+   +E  PGG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI + GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ PF  K   + D S    D + EE+R  S+T K  +EF  F
Sbjct:   18 EFLAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNF-DDYEEEEIR-VSITEKCGKEFCEF 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. TrEMBL
Match: A0A564Z0W2 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS11015 PE=3 SV=1)

HSP 1 Score: 275.404 bits (703), Expect = 3.753e-86
Identity = 146/345 (42.32%), Postives = 218/345 (63.19%), Query Frame = 3
Query:   93 VESDFPGMWDKLTWEFLGRLKENPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNP----DYSQMKKDEKIEEMRDKSLTLKYFEEF 1109
             +++F  +    + EF+ ++  +P     +WD F  IR LG+G FGRV+L R+K    Y A+K++ K  I+K +QI   I EK ILA    + + RL  TF+ N  +   +E  PGG+L+ +++    F    ++FY++QVLL  +YLH + I YRDLKPENIL+  +G++K+ D+GFAK L    RT+T CGTP+Y+APE+++NKGYG AVDWWAFGVL+YE+     PF + +QIK F +I+ GK K  ++ S + K LI+ L+Q D +KR GNL+NG +D++ HP+F   D+  +     KPP+   +KNP    +Y Q +++E I   R+K  T   FEEF
Sbjct:    2 TQAEFEQILASKSEEFM-QVYNSPPKGNASWDVFTRIRTLGKGAFGRVLLVRYKDTEKYYAMKVLSKLDIVKSRQITSAILEKKILASVNIEQITRLAYTFKDNSFLYLVMEFIPGGELFTLLRSMKSFSEAMVKFYAAQVLLAFEYLHYLTITYRDLKPENILLTADGFVKVTDLGFAKMLPIDKRTWTVCGTPDYMAPEIIMNKGYGHAVDWWAFGVLLYEMTAGFPPFMHQEQIKTFEHIISGKLKFTNQFSSDLKDLIRNLIQTDLSKRYGNLKNGVMDIKGHPYFVDTDFMGIFNHNAKPPYIPKVKNPGDASNYEQWEEEELIVSEREKFAT--EFEEF 343          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. TrEMBL
Match: A0A0R3SUN0 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS9215 PE=3 SV=1)

HSP 1 Score: 275.404 bits (703), Expect = 4.559e-86
Identity = 146/345 (42.32%), Postives = 218/345 (63.19%), Query Frame = 3
Query:   93 VESDFPGMWDKLTWEFLGRLKENPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNP----DYSQMKKDEKIEEMRDKSLTLKYFEEF 1109
             +++F  +    + EF+ ++  +P     +WD F  IR LG+G FGRV+L R+K    Y A+K++ K  I+K +QI   I EK ILA    + + RL  TF+ N  +   +E  PGG+L+ +++    F    ++FY++QVLL  +YLH + I YRDLKPENIL+  +G++K+ D+GFAK L    RT+T CGTP+Y+APE+++NKGYG AVDWWAFGVL+YE+     PF + +QIK F +I+ GK K  ++ S + K LI+ L+Q D +KR GNL+NG +D++ HP+F   D+  +     KPP+   +KNP    +Y Q +++E I   R+K  T   FEEF
Sbjct:    2 TQAEFEQILANKSEEFM-QVYNSPPKGNASWDVFTRIRTLGKGAFGRVLLVRYKDTEKYYAMKVLSKLDIVKSRQITSAILEKKILASVNIEQITRLAYTFKDNSFLYLVMEFIPGGELFTLLRSMKSFSEAMVKFYAAQVLLAFEYLHYLTITYRDLKPENILLTADGFVKVTDLGFAKMLPIDKRTWTVCGTPDYMAPEIIMNKGYGHAVDWWAFGVLLYEMTAGFPPFMHQEQIKTFEHIISGKLKFTNQFSSDLKDLIRNLIQTDLSKRYGNLKNGVMDIKGHPYFVDTDFMGIFNHNAKPPYIPKVKNPGDASNYEQWEEEELIVSEREKFAT--EFEEF 343          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. TrEMBL
Match: A0A3P9PHK6 (Uncharacterized protein OS=Poecilia reticulata OX=8081 PE=3 SV=1)

HSP 1 Score: 275.018 bits (702), Expect = 2.177e-85
Identity = 150/349 (42.98%), Postives = 218/349 (62.46%), Query Frame = 3
Query:   99 SDFPGMWDKLTWEFLGRLKEN-------PVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            S+F  MWDKL  EFL + KE+       P    T  D+FE  + LG G FGRV+L RHK  N + A+KI++K+K++K+KQI   + EK IL    F FL+RL   F+ N N+   +E  PGG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI  +GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ PF    + P  +    D + E++R  S T K  +EF +F
Sbjct:   35 SEFTVMWDKLMKEFLAKAKEDFLRKWECPAQCTTTLDEFERFKTLGTGSFGRVMLVRHKGTNQFYAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRTGRFSEHHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFSTTDWIAIYERKIEAPFLPKCRGPGDTSNFDDYEEEDIR-VSQTEKCAKEFADF 380          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. TrEMBL
Match: I3JKF0 (Uncharacterized protein OS=Oreochromis niloticus OX=8128 GN=prkacb PE=3 SV=1)

HSP 1 Score: 274.633 bits (701), Expect = 2.554e-85
Identity = 150/349 (42.98%), Postives = 219/349 (62.75%), Query Frame = 3
Query:   99 SDFPGMWDKLTWEFLGRLKEN-------PVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            S+F  MWDK   EFL + KE+       P    T+ DDFE  + LG G FGRV+L +HK+ N + A+KI++K+K++K+KQI   + EK IL    F FL+RL   F+ N N+   +E  PGG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI  +GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ PF    + P  +    D + EE+R  S T K  +EF +F
Sbjct:   36 SEFTIMWDKCMKEFLAKAKEDFLRKWECPPQCTTSLDDFERFKTLGTGSFGRVMLVKHKATNQFYAMKILDKQKVVKLKQIEHTLNEKKILQAVSFPFLVRLVYAFKDNSNLYMVMEYVPGGEMFSHLRRTGRFSEHHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFSTTDWIAIYERKVEAPFLPKCRGPGDTSNFDDYEEEEIR-VSQTEKCAKEFADF 381          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. TrEMBL
Match: A0A315US60 (Uncharacterized protein OS=Gambusia affinis OX=33528 GN=CCH79_00015021 PE=3 SV=1)

HSP 1 Score: 274.633 bits (701), Expect = 2.731e-85
Identity = 150/349 (42.98%), Postives = 218/349 (62.46%), Query Frame = 3
Query:   99 SDFPGMWDKLTWEFLGRLKEN-------PVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            S+F  MWDKL  EFL + KE+       P    T  D+FE  + LG G FGRV+L RHK  N + A+KI++K+K++K+KQI   + EK IL    F FL+RL   F+ N N+   +E  PGG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI  +GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ PF    + P  +    D + E++R  S T K  +EF +F
Sbjct:   35 SEFTVMWDKLMKEFLAKAKEDFLRKWECPAQCTTTLDEFERFKTLGTGSFGRVMLVRHKGTNQFYAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRTGRFSEHHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFSTTDWIAIYERKVEAPFLPKCRGPGDTSNFDDYEEEDIR-VSQTEKCAKEFADF 380          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Match: ENSAMXT00000056663.1 (protein kinase cAMP-activated catalytic subunit beta [Source:NCBI gene;Acc:103029308])

HSP 1 Score: 264.233 bits (674), Expect = 1.740e-84
Identity = 145/348 (41.67%), Postives = 213/348 (61.21%), Query Frame = 3
Query:   99 SDFPGMWDKLTWEFLGRLKEN-------PVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNPDYSQMKKDEKIEEMR--DKSLTLKYFEEF 1109
            S++  +WD    EFL + KE+       P    T  DDFE ++ LG G FGRV+L +HK+   Y A+KI++K+K++K+KQI   + EK IL    F FL+RL   F+ N N+   +E  PGG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI  +GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ P     + P  +    D + EE+R  D     K F EF
Sbjct:   50 SEYTLIWDGRMKEFLAKAKEDFLRKWECPPQSTTCLDDFERLKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEHHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYERKVEAPIIPKCRGPGDTSNFDDYEEEEIRISDTEKCAKEFLEF 395          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Match: prkacaa (cAMP-dependent protein kinase catalytic subunit alpha [Source:NCBI gene;Acc:103024963])

HSP 1 Score: 262.307 bits (669), Expect = 3.189e-84
Identity = 143/337 (42.43%), Postives = 208/337 (61.72%), Query Frame = 3
Query:  135 EFLGRLKE-------NPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            EFL + KE       NP     + D FE ++ LG G FGRV+L +HK    + A+KI++K+K++K+KQI   + EK IL    F FL+RL  +F+ N N+   +E  PGG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI   GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ PF    K P  +    D + EE+R  S T K  +EF  F
Sbjct:   19 EFLAKAKEDFLKKWENPAQNTASLDQFERLKTLGTGSFGRVMLVKHKETGQHFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEHSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKGHKWFATTDWIAIYQRKVEAPFIPKCKGPGDTSNFDDYEEEEIR-VSFTEKCGKEFAEF 352          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Match: prkacbb (cAMP-dependent protein kinase catalytic subunit beta [Source:NCBI gene;Acc:103034112])

HSP 1 Score: 260.381 bits (664), Expect = 1.682e-83
Identity = 141/337 (41.84%), Postives = 211/337 (62.61%), Query Frame = 3
Query:  135 EFLGRLKEN-------PVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            EFL + KE+       P    T  DDFE ++ LG G FGRV+L +HK    + A+K+++K+K++K+KQI   + EK IL    F FL+RL  +F+ N N+   +E  PGG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI  +GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ PF    + P  +    D + E++R  S+T K  +EF  F
Sbjct:   18 EFLAKAKEDFLRKWECPPQSTTTLDDFERLKTLGTGSFGRVMLVKHKGTEQFFAMKVLDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKNHKWFATTDWIAIYERKVEAPFIPKCRGPGDTSNFDDYEEEDIR-VSVTEKCAKEFTEF 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Match: prkacaa (cAMP-dependent protein kinase catalytic subunit alpha [Source:NCBI gene;Acc:103024963])

HSP 1 Score: 261.922 bits (668), Expect = 3.072e-83
Identity = 143/337 (42.43%), Postives = 208/337 (61.72%), Query Frame = 3
Query:  135 EFLGRLKE-------NPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            EFL + KE       NP     + D FE ++ LG G FGRV+L +HK    + A+KI++K+K++K+KQI   + EK IL    F FL+RL  +F+ N N+   +E  PGG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI   GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ PF    K P  +    D + EE+R  S T K  +EF  F
Sbjct:   86 EFLAKAKEDFLKKWENPAQNTASLDQFERLKTLGTGSFGRVMLVKHKETGQHFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEHSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKGHKWFATTDWIAIYQRKVEAPFIPKCKGPGDTSNFDDYEEEEIR-VSFTEKCGKEFAEF 419          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Match: ENSAMXT00000050353.1 (protein kinase cAMP-activated catalytic subunit beta [Source:NCBI gene;Acc:103029308])

HSP 1 Score: 259.225 bits (661), Expect = 3.943e-83
Identity = 142/336 (42.26%), Postives = 207/336 (61.61%), Query Frame = 3
Query:  135 EFLGRLKEN-------PVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNPDYSQMKKDEKIEEMR--DKSLTLKYFEEF 1109
            EFL + KE+       P    T  DDFE ++ LG G FGRV+L +HK+   Y A+KI++K+K++K+KQI   + EK IL    F FL+RL   F+ N N+   +E  PGG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI  +GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ P     + P  +    D + EE+R  D     K F EF
Sbjct:   18 EFLAKAKEDFLRKWECPPQSTTCLDDFERLKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEHHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYERKVEAPIIPKCRGPGDTSNFDDYEEEEIRISDTEKCAKEFLEF 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001814.1 (pep scaffold:Pmarinus_7.0:GL481074:830:17391:1 gene:ENSPMAG00000001637.1 transcript:ENSPMAT00000001814.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 229.565 bits (584), Expect = 4.609e-73
Identity = 115/266 (43.23%), Postives = 166/266 (62.41%), Query Frame = 3
Query:  327 VIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
             + EK IL    F FL+RL  +F+ N N+   LE  PGG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI   GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ PF    K P  +    D + EE+R  S T K  +EF +F
Sbjct:   26 TLNEKRILQAISFPFLVRLEYSFKDNSNLYMVLEYVPGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFSTTDWIAIYQRKVEAPFIPKCKGPGDASNFDDYEEEEIRISS-TEKCAKEFADF 288          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Match: PRKCD (protein kinase C delta [Source:HGNC Symbol;Acc:HGNC:9399])

HSP 1 Score: 208.379 bits (529), Expect = 3.579e-62
Identity = 112/287 (39.02%), Postives = 176/287 (61.32%), Query Frame = 3
Query:  174 KTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILAL-CKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQA--IRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAK-FLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPFPIK 1022
            K + D F  +++LG+G FG+V+L+  K +  + A+K ++KE ++    +   + EK +L + C+  FL  L  TFQT +++ F +E   GGDL   I+    FD+     RFY+++V+ GLQ+LH+  I+YRDLK +N+L+   G++K+AD G  K  +       TFCGTP+YIAPE++L + YGT+VDWW+ GVLIYE+    +PFY +D+ ++F  I       P  LS  +++++  L + D TKR+G +     D+R HPFFK IDW  +  + + PPF  K
Sbjct:  246 KLSLDHFHLLKVLGKGSFGKVMLAELKEQGKFFAIKALKKEVVLMGDDVECTMVEKRVLLMACEHPFLTHLCGTFQTKEHLFFVMEFLTGGDLMFHIQDKGKFDLPTGTNRFYAAEVICGLQFLHSHNIIYRDLKLDNVLLDREGHVKIADFGMCKEHVGAGNLATTFCGTPDYIAPEILLGRAYGTSVDWWSMGVLIYEMLIGQSPFYGSDEDELFEAIKGHTPHYPRWLSDSSRNILSCLFERDHTKRLGAVG----DIRLHPFFKNIDWPSLEARKITPPFKPK 528          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008480.1 (pep scaffold:Pmarinus_7.0:GL482122:191709:206473:1 gene:ENSPMAG00000007654.1 transcript:ENSPMAT00000008480.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 205.682 bits (522), Expect = 1.273e-61
Identity = 110/282 (39.01%), Postives = 170/282 (60.28%), Query Frame = 3
Query:  174 KTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMR-IVYRDLKPENILIANNGYIKLADMGFAKF-LQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF 1013
            K   ++F+++++LG+G FG+VIL R K+   Y A+KI++KE I+   ++   + E  +L   K  FL  L  +FQT+D +CF +E   GG+L+  +     F     RFY ++++  L YLHT + +VYRDLK EN+++  +G+IK+AD G  K  + D     TFCGTPEY+APEV+ +  YG AVDWW  GV++YE+     PFY  D  K+F  I+    + P  LS +A++L+  LL+ D  +R+G   + A ++  H FF  I W D+  + + PPF
Sbjct:  144 KVTMNNFDYLKLLGKGTFGKVILVREKATGQYYAMKILKKEVIVAKDEVAHTLTENRVLQTTKHPFLTLLKYSFQTHDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHTEKNVVYRDLKLENLMLDKDGHIKIADFGLCKEGITDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIRFPRTLSNDARALLSGLLKKDPKQRLGGGVDDAKEIMRHSFFAGIIWQDVYDRKMTPPF 425          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002200.1 (pep scaffold:Pmarinus_7.0:GL479132:31244:36905:-1 gene:ENSPMAG00000001993.1 transcript:ENSPMAT00000002200.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 201.445 bits (511), Expect = 1.666e-61
Identity = 107/273 (39.19%), Postives = 162/273 (59.34%), Query Frame = 3
Query:  201 IRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKI--PHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF 1013
            I  LG GGFGRV L + K  ++  ALK ++K+ +++ +Q   V  EK IL  C   F++R Y TF+    +   +E   GG+L+ V++    F   + RF  + V+  L YLH   I+YRDLKPEN+L+   GYIK+AD GFAK L    + +TFCGTPEY+ PE+++N+G+    D WA GVL+YEL     PF  TD +K +  I+ G  ++  P+E+   A+ +I+ L + + ++R+GN ++G  DVR H +F+  DW  +    L  P 
Sbjct:   37 IATLGVGGFGRVQLVKLKDSDVTFALKCLKKKFVVESRQQEHVYSEKRILQECSCPFIVRFYRTFRDQKFVFLLMEACLGGELWSVLRDSGGFQEVSARFCVACVVEALAYLHARGILYRDLKPENLLLDARGYIKMADFGFAKKLACGRKAWTFCGTPEYVCPEMIVNRGHDRGADCWALGVLVYELLAGVPPFSGTDPMKTYNAILWGMERVHFPNEVGKRAEDIIRRLCRQNPSERLGNQKHGVGDVRKHKWFQGFDWESLRSNQLASPL 309          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Match: PRKCD (protein kinase C delta [Source:HGNC Symbol;Acc:HGNC:9399])

HSP 1 Score: 175.637 bits (444), Expect = 1.566e-52
Identity = 88/228 (38.60%), Postives = 143/228 (62.72%), Query Frame = 3
Query:  336 EKTILALC-KFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAK-FLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF 1013
            EK IL+L     +L  LY+TFQT +++ F +E   GGDL   I++   F++    FY+++++ GLQ+LH   I+YRDLK +NIL+  +G++K+AD G  K  +    R  TFCGTP+YIAPE+V+ + Y  +VDWW+FGVL+YE+    +PF   D+ ++F +I       P  ++ +++ ++  LL+ +  KR+G       ++R HPFF+ I+W  +  + L+PPF
Sbjct:   37 EKRILSLAWGHPYLAHLYSTFQTKEHLMFVMEYLNGGDLMFHIQVKGRFEIDRATFYAAEIVSGLQFLHDQGIIYRDLKLDNILLDKDGHVKIADFGMCKENIVGDVRAGTFCGTPDYIAPEIVIGQKYNCSVDWWSFGVLLYEMLIGQSPFRGDDEEELFESIRTSVPYYPRWITKDSRDILPLLLEREPMKRLGV----TGEIRQHPFFRTINWEALEKRELEPPF 260          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Yeast
Match: TPK3 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649])

HSP 1 Score: 230.335 bits (586), Expect = 3.322e-72
Identity = 115/280 (41.07%), Postives = 181/280 (64.64%), Query Frame = 3
Query:  174 KTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF 1013
            K +  DF+ +R LG G FGRV L R      + ALK ++K  I+K+KQ+     E+ +L++    F++R++ TFQ +  +   ++   GG+L+ +++    F     +FY+++V L L+YLH+  I+YRDLKPENIL+  NG+IK+ D GFAK++ D   TYT CGTP+YIAPEVV  K Y  +VDWW+FGVLIYE+    TPFY ++ +K + NI+  + K P     +A+ L+K L+  D ++R+GNL+NG+ DV+ HP+F  + W  ++ + ++ P+
Sbjct:   82 KYSLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDV--TYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWFNEVIWEKLLARYIETPY 359          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Yeast
Match: TPK1 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700])

HSP 1 Score: 225.713 bits (574), Expect = 2.179e-70
Identity = 117/296 (39.53%), Postives = 188/296 (63.51%), Query Frame = 3
Query:  174 KTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIK--NPDYSQMKK 1049
            K +  DF+ +R LG G FGRV L R +    Y A+K+++KE ++++KQ+     E+ +L++    F++R++ TFQ    I   ++   GG+L+ +++    F     +FY+++V L L+YLH+  I+YRDLKPENIL+  NG+IK+ D GFAK++ D   TYT CGTP+YIAPEVV  K Y  ++DWW+FG+LIYE+    TPFY ++ +K +  I+  + + P   + + K L+  L+  D ++R+GNL+NG  DV+ HP+FK + W  ++ + ++ P+  PI+    D SQ  K
Sbjct:   81 KYSLQDFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDV--TYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFFNEDVKDLLSRLITRDLSQRLGNLQNGTEDVKNHPWFKEVVWEKLLSRNIETPYEPPIQQGQGDTSQFDK 374          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Yeast
Match: TPK2 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124])

HSP 1 Score: 221.09 bits (562), Expect = 6.540e-69
Identity = 123/314 (39.17%), Postives = 191/314 (60.83%), Query Frame = 3
Query:  189 DFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNPDYSQMKKDEKIEEMRDKSLT-----LKYFEEF 1109
            DF+ +R LG G FGRV L R      Y A+K+++K++++KMKQ+     E+ +L L +  FL+R++ TFQ   NI   ++   GG+L+ +++    F     +FY+++V+L L+YLH   I+YRDLKPENIL+  NG+IK+ D GFAK +Q    T+T CGTP+YIAPEV+  K Y  +VDWW+ GVLIYE+    TPFY T  +K +  I++GK   P     +   L+  L+  D T+RIGNL++G+ D++ HP+F  + W  ++ + ++ P+  PI +        D+  EE  D  +       +YF++F
Sbjct:   69 DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTV--TWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVDLLSKLITADLTRRIGNLQSGSRDIKAHPWFSEVVWERLLAKDIETPYEPPITSGIGDTSLFDQYPEEQLDYGIQGDDPYAEYFQDF 380          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Yeast
Match: YPK1 (S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609])

HSP 1 Score: 200.29 bits (508), Expect = 3.020e-58
Identity = 106/277 (38.27%), Postives = 165/277 (59.57%), Query Frame = 3
Query:  186 DDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKF-LQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF 1013
            DDF+ ++++G+G FG+V+  R K      ALK + K  I+   ++   + E+T+LA     F++ L  +FQ+ + + F L    GG+L+  ++    FD+   RFY++++L  L  LH + +VYRDLKPENIL+   G+I L D G  K  ++D  +T TFCGTPEY+APE++L  GY  AVDWW  GVL+YE+     P+Y  D  K+++ I++     P     +AK L+  LL  D T+R+G   NGA ++R HPFF  + W  ++ +   PP+
Sbjct:  345 DDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPDGFDRDAKDLLIGLLSRDPTRRLG--YNGADEIRNHPFFSQLSWKRLLMKGYIPPY 619          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Yeast
Match: KIN82 (Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687])

HSP 1 Score: 196.823 bits (499), Expect = 8.926e-57
Identity = 114/297 (38.38%), Postives = 168/297 (56.57%), Query Frame = 3
Query:  192 FEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSP--FDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFA-------------------KFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPH--ELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF 1013
            FE IR+LG+G  G+V L R +  N   ALK++ K ++IK K+I  V+ E+ ILA     F++ LY +FQT D +  C+E   GG+ +  ++         +  +FY+S+V+  L+YLH +  +YRDLKPENIL+  +G++ L+D   +                   K   D  RT +F GT EY+APEV+   G+  AVDWW  G+LIYE+ F  TPF   +  + F NI+    K PH  E+S   K LIK LL  +  KR+G+ ++GA D++ HPFFK + W+ +  Q   PP 
Sbjct:  324 FEKIRLLGQGDVGKVYLVRERDTNQIFALKVLNKHEMIKRKKIKRVLTEQEILATSDHPFIVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLLGFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVIRGNGHTAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNILTKDVKFPHDKEVSKNCKDLIKKLLNKNEAKRLGS-KSGAADIKRHPFFKKVQWSFLRNQ--DPPL 617          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Match: EDO35228 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM62])

HSP 1 Score: 225.328 bits (573), Expect = 1.062e-70
Identity = 131/321 (40.81%), Postives = 195/321 (60.75%), Query Frame = 3
Query:  168 DRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIP-HELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNPDYSQMKKDEKIEEMRDK-SLTLKYFEEFKNF 1118
            D++T   DFE  + LG G FGRV+L+R +    + ALKIM   ++I++KQ+  V  EK IL   +  F++ L  T      +   LE A GG+L+  ++    F+     F+ S+++  + YLH   IVYRDLKPENIL+  +G++KL D GFAK + D  +T+T CGTPEY+APE++ +KG+  AVDWWA G+LIYE+     PF+  +   I+  I+ GK + P H  +  AK LIK LL  D T+R+G+++NG+ DV+ H +FK+IDW  ++ + LKPP    I +P  ++   D   E+ R    L  K+ E FK+F
Sbjct:   10 DKRTTLQDFELSKTLGTGTFGRVLLARDRRGGEFYALKIMNISEVIRLKQVEHVQNEKNILMSIEHPFIVNLLWTQHDQTFLYMLLEYACGGELFTYLRTAGRFNNGTGLFFGSEIVSAMDYLHGHSIVYRDLKPENILLDRDGHVKLTDFGFAKEVHD--KTWTLCGTPEYLAPEIIQSKGHNKAVDWWALGILIYEMLVGYPPFFDDNPFGIYEKILSGKVEWPKHMDNTSAKDLIKKLLVHDRTRRLGSMKNGSEDVKNHKWFKVIDWNLVLQRKLKPPINPKISHPGDTRNFDDYPEEDWRGAPPLNAKHLEPFKDF 328          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Match: EDO37800 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEW2])

HSP 1 Score: 200.29 bits (508), Expect = 4.223e-60
Identity = 110/316 (34.81%), Postives = 183/316 (57.91%), Query Frame = 3
Query:   96 ESDFPGMWDKLTWEFLGRLKENPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILAL-CKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAK-FLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPFPIKNPDYS 1037
            E + PG  D    +       NP   K    DF  ++++G+G FG+V LS++K ++ + A+K++ K  I K  +   ++ E+ +L       FL+ L+ +FQT D + F L+   GG+L+  ++    F     RFY++++   + YLH ++I+YRDLKPENIL+ + G+I L D G  K  +  S  T TFCGTPEY+APEV+  + Y  +VDWW  G ++YE+ +   PFY  D  +++ NI+    ++   +S  A+ +++ LLQ D TKR+G+      D+R H FF+ I+W  ++ + ++PP+   NP+ S
Sbjct:   45 EDEQPGSDDADVEKIDLGESNNP---KAKPSDFLFLKVIGKGSFGKVFLSKNKQEDKFYAIKVLNKSAIRKRNEAKHIMAERNVLVQNVTHPFLVGLHYSFQTKDKLYFVLDYVNGGELFFHLQRERYFPESRARFYAAEIASAIGYLHGLQIIYRDLKPENILLDSKGHIVLTDFGLCKEGIDRSGTTSTFCGTPEYLAPEVLRKQDYDKSVDWWCLGAVLYEMMYGLPPFYSRDTAEMYDNILHKPLRLRTNISQSARHILEGLLQKDKTKRLGSGEGDFEDIRTHSFFRSINWQQLVARGIEPPY---NPNVS 354          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Match: EDO41166 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S521])

HSP 1 Score: 199.134 bits (505), Expect = 1.629e-59
Identity = 106/290 (36.55%), Postives = 163/290 (56.21%), Query Frame = 3
Query:  159 NPVDRKTAWDDFEHIRILGEGGFGRVILSR----HKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAK-FLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF 1013
            NP D K   + FE +++LG+GG+G+V L +    H  + ++    + +   I   K       E+ IL   K  F++ L   FQT   +   LE   GG+L+  ++    F      FY S++ + L++LH   IVYRDLKPENIL+  NG++KL D G  K  + ++  T+TFCGT EY+APE++   G+G AVDWW+ G L+Y++   T PF   ++ K    I+KGK  IP  L+ EAK  I+ LL+     R+G +   A  ++ H FF+ I W D++ + ++PPF
Sbjct:   54 NPKDEKVGPESFELLKVLGKGGYGKVFLVKKNHGHSKEKIFAMKVLKKAAIIRSQKDTAHTKAERNILECVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFLEDTACFYLSEISMALEHLHKQGIVYRDLKPENILLDANGHVKLTDFGLCKESIFENSLTHTFCGTIEYMAPEILTRSGHGKAVDWWSLGALMYDMLTGTPPFCADNRKKTIDKILKGKLIIPPYLTPEAKDFIRKLLKRHPQARLGGMAGDANPIKAHSFFRHICWEDLLAKKVEPPF 343          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Match: EDO38407 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCZ7])

HSP 1 Score: 195.667 bits (496), Expect = 3.764e-56
Identity = 109/285 (38.25%), Postives = 168/285 (58.95%), Query Frame = 3
Query:  186 DDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKI--PHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPFP--IKNP 1028
            +D   ++ LG GGFGRV L +        ALK ++K  I++ +Q   ++ EK I+      F++RL+ TF+    +   LE+  GG+L+ +++    FD    RFY   V+   QYLH+  IVYRDLKPEN+L+  +GY KL D GFAK +    +T+TFCGTPEY+APE++LNKG+  + D+W+ G+L+YEL   + PF  TD +K +  I+KG   I  P +++  A +LIK L + +  +R+G  + G  D+  H +F   +W  +  + L  P    IK+P
Sbjct:  350 EDLTVVKTLGIGGFGRVELVQVAGDKRTFALKTLKKHHIVETRQQDHIMSEKKIMMESNSPFIVRLHKTFKDKKYLYMLLEVCLGGELWTILRDRGSFDDSTTRFYVGCVIEAFQYLHSKGIVYRDLKPENLLLDGHGYCKLVDFGFAKKIGFGRKTWTFCGTPEYVAPEIILNKGHDLSADYWSLGILMYELLTGSPPFSGTDPMKTYNIILKGIDMIDFPRKITRNAHALIKKLCRDNPVERLGYQKGGLKDIMKHKWFDGFNWDGLRSRKLNSPIAPKIKSP 634          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Match: EDO31895 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWM6])

HSP 1 Score: 189.889 bits (481), Expect = 1.564e-54
Identity = 101/285 (35.44%), Postives = 164/285 (57.54%), Query Frame = 3
Query:  171 RKTAWDDFEHIRILGEGGFGRVILSRH----KSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF 1013
            +K     FE +++LG+G FG+V L R      +  LY     + K+  +K++     + E+ IL   +  F++RL   FQT   +   L+   GGDL+  +     F  + ++FY +++ L L +LH + I+YRDLKPENIL+  +G++ L D G +K  +   +TY+FCGT EY+APEVV  +G+  A DWW++GVL++E+   + PF   D+      I+K K  +P  L+ EA+SL++ L + +   R+G    G  D++ HPFF  I+W  +  + +KPPF
Sbjct:    2 KKADPSQFELLKVLGQGSFGKVFLVRKVIGADAGTLYA--MKVLKKATLKVRDRMRTMKERDILVDVQHPFIVRLNYAFQTEGKVYLILDFLRGGDLFTRLSKEIMFTEEDVKFYLAELALALDHLHGLGIIYRDLKPENILLDASGHVALTDFGLSKESEHDQKTYSFCGTVEYMAPEVVNRRGHSQAADWWSYGVLMFEMLTGSLPFQGKDRKDTMNMILKAKLGMPQFLTPEAQSLLRQLFKRNPLNRLGAGDLGIEDIKKHPFFSTINWELLYKREIKPPF 284          

HSP 2 Score: 77.411 bits (189), Expect = 2.207e-15
Identity = 47/165 (28.48%), Postives = 81/165 (49.09%), Query Frame = 3
Query:  372 LLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNG----YIKLADMGFAKFLQDSPRT-YTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIK---IFRNIVKGKYKI 842
            ++ L   ++    +   +EL  GG+L   I  +     +        +   + +LH   +V+RDLKP NI+ A++      +++ D GFAK ++ +     T C T  ++APEV+  +GY  A D W+ GVL+Y +    TPF    +     I + I +GKY +
Sbjct:  410 IVHLRDAYEAGKQVYIVMELMRGGELLDRILKHKCLSEREAGNIMYTLTSTIAFLHEEGVVHRDLKPSNIMYADDSGTPESLRIVDFGFAKQMRATNGLLMTPCYTANFVAPEVLKKQGYDAACDIWSLGVLLYTMLSGLTPFAVGPEDTPSVILKRIGEGKYSL 574          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Medaka
Match: ENSORLT00000028912.1 (protein kinase cAMP-activated catalytic subunit beta [Source:NCBI gene;Acc:101160305])

HSP 1 Score: 270.781 bits (691), Expect = 3.775e-87
Identity = 151/350 (43.14%), Postives = 218/350 (62.29%), Query Frame = 3
Query:   99 SDFPGMWDKLTWEFLGRLKEN-------PVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNP-DYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            S+F   WDKL  EFL + KE+       P    T+ DDFE  + LG G FGRV+L +HK+ N + A+KI++K+K++K+KQI   + EK IL    F FL+RL   F+ N N+   +E  PGG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI  +GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ PF    + P D S    D+  EE    S T K  +EF +F
Sbjct:   35 SEFTITWDKLMKEFLAKAKEDFLRKWECPPQCTTSLDDFERFKTLGTGSFGRVMLVKHKATNQFYAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLVYAFKDNSNLYMVMEYVPGGEMFSHLRRTGRFSEHHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKKVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFSTTDWIAIYERKIEAPFLPKCRGPGDTSNF--DDYEEEDIHVSQTEKCGKEFADF 380          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Medaka
Match: ENSORLT00000035979.1 (cAMP-dependent protein kinase catalytic subunit beta [Source:NCBI gene;Acc:101170876])

HSP 1 Score: 264.233 bits (674), Expect = 5.804e-85
Identity = 146/342 (42.69%), Postives = 213/342 (62.28%), Query Frame = 3
Query:  120 DKLTWEFLGRLKEN-------PVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            D    EFL + KE+       P    T  +DF+ I+ LG G FGRV+L +HKS   Y A+KI++K+K++K+KQI   + EK IL    F FL+RL   F+ N N+   +E  PGG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI ++GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ PF    + P  +    D + EE+R  SLT K  +EF  F
Sbjct:   16 DTFVKEFLAKAKEDFLRKWECPPQSTTCLEDFDRIKTLGTGSFGRVMLVKHKSSEQYFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHHGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKGHKWFATTDWIAIYERKVEAPFIPKCRGPGDTSNFDDYEEEEIR-VSLTEKCAKEFAEF 354          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Medaka
Match: ENSORLT00000033457.1 (cAMP-dependent protein kinase catalytic subunit beta [Source:NCBI gene;Acc:101170876])

HSP 1 Score: 263.462 bits (672), Expect = 9.900e-85
Identity = 145/337 (43.03%), Postives = 212/337 (62.91%), Query Frame = 3
Query:  135 EFLGRLKEN-------PVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            EFL + KE+       P    T  +DF+ I+ LG G FGRV+L +HKS   Y A+KI++K+K++K+KQI   + EK IL    F FL+RL   F+ N N+   +E  PGG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI ++GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ PF    + P  +    D + EE+R  SLT K  +EF  F
Sbjct:   18 EFLAKAKEDFLRKWECPPQSTTCLEDFDRIKTLGTGSFGRVMLVKHKSSEQYFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHHGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKGHKWFATTDWIAIYERKVEAPFIPKCRGPGDTSNFDDYEEEEIR-VSLTEKCAKEFAEF 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Medaka
Match: ENSORLT00000007944.2 (protein kinase cAMP-activated catalytic subunit beta [Source:NCBI gene;Acc:101160305])

HSP 1 Score: 259.996 bits (663), Expect = 2.096e-83
Identity = 145/338 (42.90%), Postives = 211/338 (62.43%), Query Frame = 3
Query:  135 EFLGRLKEN-------PVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNP-DYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            EFL + KE+       P    T+ DDFE  + LG G FGRV+L +HK+ N + A+KI++K+K++K+KQI   + EK IL    F FL+RL   F+ N N+   +E  PGG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI  +GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNL+NG  D++ H +F   DW  +  + ++ PF    + P D S    D+  EE    S T K  +EF +F
Sbjct:   18 EFLAKAKEDFLRKWECPPQCTTSLDDFERFKTLGTGSFGRVMLVKHKATNQFYAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLVYAFKDNSNLYMVMEYVPGGEMFSHLRRTGRFSEHHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKKVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFSTTDWIAIYERKIEAPFLPKCRGPGDTSNF--DDYEEEDIHVSQTEKCGKEFADF 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Medaka
Match: prkacaa (cAMP-dependent protein kinase catalytic subunit alpha [Source:NCBI gene;Acc:101163742])

HSP 1 Score: 259.61 bits (662), Expect = 3.227e-83
Identity = 142/337 (42.14%), Postives = 208/337 (61.72%), Query Frame = 3
Query:  135 EFLGRLKE-------NPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPF--PIKNPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            EFL + KE       NP  +  A D FE ++ LG G FGRV+L +HK    + A+KI++K+K++K+KQI   + EK IL    F FL++L  +F+   N+   +E  PGG+++  ++    F     RFY++Q++L  +YLH++ ++YRDLKPEN+LI   GYI++ D GFAK ++   RT+T CGTPEY+APE++L+KGY  AVDWWA GVLIYE+     PF+    I+I+  IV GK + P   S + K L++ LLQ+D TKR GNLRNG  D++ H +F   DW  +  + ++ PF    K P  +    D + EE+R  S + K  +EF  F
Sbjct:   18 EFLAKAKEDFLKKWENPAQQTAALDHFERLKTLGTGSFGRVMLVKHKETGQHFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVQLEHSFKDTSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLRNGVNDIKGHKWFATTDWIAIYQRKVEAPFIPKCKGPGDTSNFDDYEEEEIR-VSFSEKCAKEFAEF 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Planmine SMEST
Match: SMESG000051702.1 (SMESG000051702.1)

HSP 1 Score: 691.804 bits (1784), Expect = 0.000e+0
Identity = 353/353 (100.00%), Postives = 353/353 (100.00%), Query Frame = 3
Query:   60 MHKPIDKIPLRVESDFPGMWDKLTWEFLGRLKENPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPFPIKNPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            MHKPIDKIPLRVESDFPGMWDKLTWEFLGRLKENPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALKIMEKEKIIKMKQIPIVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPFPIKNPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF
Sbjct:    1 MHKPIDKIPLRVESDFPGMWDKLTWEFLGRLKENPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALKIMEKEKIIKMKQIPIVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPFPIKNPDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 353          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Planmine SMEST
Match: SMESG000077092.1 (SMESG000077092.1)

HSP 1 Score: 262.307 bits (669), Expect = 1.743e-84
Identity = 134/296 (45.27%), Postives = 194/296 (65.54%), Query Frame = 3
Query:   99 SDFPGMWDKLTWEFLGRLKENPVDRKTAWDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDM 986
            +DF  +  K   EFL +  +NP       +DFE I+ LG+G FGRVIL +HK+   Y ALK++ K +IIK KQI   + EK ILA  +F FL+ L  +F+ N  +   LE   GG+++ +++    F    ++FY +QV++  +YLH + I YRDLKPENIL+ ++GY+K+ DMGFAK +    RT+T CGTP+Y+APE+++NKGY  AVDWWAFGVL+YE+     PF + DQ+K F +I+ GK K     S + K LI+ L+Q+D ++R GNL+NG  D++ H +F  IDW D+
Sbjct:    2 TDFNAVLIKKHEEFLVKW-DNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDV 296          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Planmine SMEST
Match: SMESG000037955.1 (SMESG000037955.1)

HSP 1 Score: 261.151 bits (666), Expect = 5.169e-84
Identity = 127/260 (48.85%), Postives = 172/260 (66.15%), Query Frame = 3
Query:  201 IRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWT 980
            I+ LG+G FG+VIL +H       A K + K ++IK +Q+   + EK I+A C F F++ + +TFQ N N+   LE A GG+L+G+++    F    ++FY+ QVL+GL+YLH + I YRDLKPEN+LI  +GY+K+AD+GFAK +    RTYT CGTP+Y+APE++ NKGY   VDWWAFGVLIYEL     PF   DQ+K F  I+ GK+K       E K L+  LLQ+D +KR GNL+NG  D+R H FF  IDW 
Sbjct:   39 IKALGKGAFGKVILVKHIDSGRLYACKQLSKAQVIKTRQVENAMNEKNIIACCNFPFVIGIGSTFQDNTNLYLLLEFASGGELFGLLRKLKRFPEGWVKFYTCQVLMGLEYLHCLTIAYRDLKPENVLICEDGYLKVADLGFAKLIPREKRTYTLCGTPDYMAPEIIQNKGYSFPVDWWAFGVLIYELISGVPPFMQRDQMKTFERIISGKFKFTENFRPEVKDLVTNLLQVDLSKRFGNLQNGVCDIRNHEFFHEIDWV 298          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Planmine SMEST
Match: SMESG000043218.1 (SMESG000043218.1)

HSP 1 Score: 248.825 bits (634), Expect = 4.032e-79
Identity = 138/313 (44.09%), Postives = 203/313 (64.86%), Query Frame = 3
Query:  186 DDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPFPIKN--PDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            DDF  ++ LG G +GRVIL +HK K  Y A+K++EK  I+KMKQI   + EK IL    F FL++L+  F+ N  +   +E   GG+++  ++    F    ++FY+SQV+L L+YLH + ++YRDLKPENILI   GYIK+ DMGFAK ++   +T+TFCGTPEY+APEV+L+KGY  AVDWW+ GVLIYE+   + PF   + I ++  IV GK  +P   + + K L++ LLQ+D TKRIGNL+NG  D++ H +F  I+W  +  +    PF  K+  PD +    D + + ++  + T+KY +EF +F
Sbjct:   44 DDFLRLKTLGTGSYGRVILVQHKKKQTYYAMKVLEKHTIVKMKQIEHTLNEKRILQAINFPFLVKLHYHFKDNSYLYMVMEFIGGGEMFTHLRRIGKFRENHVQFYASQVVLALEYLHHLDVIYRDLKPENILIDLTGYIKITDMGFAKRVKG--KTWTFCGTPEYLAPEVILSKGYDHAVDWWSLGVLIYEMSTDSPPFSGENHIHMYEKIVSGKVFLPTYFTSDLKDLLRSLLQVDLTKRIGNLKNGVNDIKNHKWFLSINWNAVFRKEAVVPFKPKSNGPDDTDNFNDYEEQSLK-IAATVKYHKEFLDF 353          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Planmine SMEST
Match: SMESG000048623.1 (SMESG000048623.1)

HSP 1 Score: 248.825 bits (634), Expect = 6.244e-79
Identity = 142/330 (43.03%), Postives = 210/330 (63.64%), Query Frame = 3
Query:  138 FLGRLKENPVDRKTA-WDDFEHIRILGEGGFGRVILSRHKSKNLYVALXXXXXXXXXXXXXXXXVIGEKTILALCKFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSSQVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTYTFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKIFRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPFFKLIDWTDMMGQLLKPPFPIKN--PDYSQMKKDEKIEEMRDKSLTLKYFEEFKNF 1118
            FL +  +   +R  A  DDF  ++ LG G +GRVIL +HK K  Y A+K++EK  I+KMKQI   + EK IL    F FL++L+  F+ N  +   +E   GG+++  ++    F    ++FY+SQV+L L+YLH + ++YRDLKPENILI   GYIK+ DMGFAK ++   +T+TFCGTPEY+APEV+L+KGY  AVDWW+ GVLIYE+   + PF   + I ++  IV GK  +P   + + K L++ LLQ+D TKRIGNL+NG  D++ H +F  I+W  +  +    PF  K+  PD +    D + + ++  + T+KY +EF +F
Sbjct:   45 FLQKYGKISKERNVACLDDFLRLKTLGTGSYGRVILVQHKKKQTYYAMKVLEKHTIVKMKQIEHTLNEKRILQAINFPFLVKLHYHFKDNSYLYMVMEFIGGGEMFTHLRRIGKFRENHVQFYASQVVLALEYLHHLDVIYRDLKPENILIDLTGYIKITDMGFAKRVKG--KTWTFCGTPEYLAPEVILSKGYDHAVDWWSLGVLIYEMSTDSPPFSGENHIHMYEKIVSGKVFLPTYFTSDLKDLLRSLLQVDLTKRIGNLKNGVNDIKNHKWFLSINWNAVFRKEAVVPFKPKSNGPDDTDNFNDYEEQSLKIAA-TVKYHKEFLDF 371          
The following BLAST results are available for this feature:
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PRKACB2.467e-8542.00protein kinase cAMP-activated catalytic subunit be... [more]
PRKACB3.255e-8342.27protein kinase cAMP-activated catalytic subunit be... [more]
PRKACB3.902e-8342.27protein kinase cAMP-activated catalytic subunit be... [more]
PRKACB6.155e-8342.60protein kinase cAMP-activated catalytic subunit be... [more]
PRKACB7.387e-8342.60protein kinase cAMP-activated catalytic subunit be... [more]
back to top
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kin-12.000e-8242.52cAMP-dependent protein kinase catalytic subunit [... [more]
kin-12.464e-8244.41cAMP-dependent protein kinase catalytic subunit [... [more]
kin-13.274e-8242.35cAMP-dependent protein kinase catalytic subunit [... [more]
kin-14.974e-8244.37cAMP-dependent protein kinase catalytic subunit [... [more]
kin-15.066e-8244.78cAMP-dependent protein kinase catalytic subunit [... [more]
back to top
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Pka-C11.180e-7841.52gene:FBgn0000273 transcript:FBtr0335495[more]
Pka-C11.180e-7841.52gene:FBgn0000273 transcript:FBtr0079852[more]
Pka-C11.180e-7841.52gene:FBgn0000273 transcript:FBtr0079851[more]
CG120693.989e-7238.08gene:FBgn0039796 transcript:FBtr0085728[more]
CG120693.989e-7238.08gene:FBgn0039796 transcript:FBtr0335455[more]
back to top
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
prkacbb4.244e-8441.84protein kinase, cAMP-dependent, catalytic, beta b ... [more]
prkacaa1.071e-8342.43protein kinase, cAMP-dependent, catalytic, alpha, ... [more]
prkacab1.502e-8041.80protein kinase, cAMP-dependent, catalytic, alpha, ... [more]
prkacba3.096e-7840.00protein kinase, cAMP-dependent, catalytic, beta a ... [more]
prkacba3.096e-7840.00protein kinase, cAMP-dependent, catalytic, beta a ... [more]
back to top
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
prkacb1.826e-8442.73protein kinase cAMP-activated catalytic subunit be... [more]
ints83.955e-8442.27integrator complex subunit 8 [Source:Xenbase;Acc:X... [more]
ints81.180e-8342.73integrator complex subunit 8 [Source:Xenbase;Acc:X... [more]
ints81.261e-8342.73integrator complex subunit 8 [Source:Xenbase;Acc:X... [more]
ints81.317e-8342.73integrator complex subunit 8 [Source:Xenbase;Acc:X... [more]
back to top
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Prkacb4.417e-8542.57protein kinase, cAMP dependent, catalytic, beta [S... [more]
Prkacb1.271e-8242.90protein kinase, cAMP dependent, catalytic, beta [S... [more]
Prkacb1.311e-8242.90protein kinase, cAMP dependent, catalytic, beta [S... [more]
Prkacb1.557e-8242.90protein kinase, cAMP dependent, catalytic, beta [S... [more]
Prkaca3.737e-8041.25protein kinase, cAMP dependent, catalytic, alpha [... [more]
back to top
BLAST of cAMP-dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P22694|KAPCB_HUMAN2.956e-8242.60cAMP-dependent protein kinase catalytic subunit be... [more]
sp|P36887|KAPCA_PIG4.906e-8242.14cAMP-dependent protein kinase catalytic subunit al... [more]
sp|P68182|KAPCB_RAT9.170e-8242.90cAMP-dependent protein kinase catalytic subunit be... [more]
sp|P68181|KAPCB_MOUSE9.170e-8242.90cAMP-dependent protein kinase catalytic subunit be... [more]
sp|P68180|KAPCB_CRIGR9.170e-8242.90cAMP-dependent protein kinase catalytic subunit be... [more]
back to top
BLAST of cAMP-dependent protein kinase catalytic subunit vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A564Z0W23.753e-8642.32Uncharacterized protein OS=Hymenolepis diminuta OX... [more]
A0A0R3SUN04.559e-8642.32Uncharacterized protein OS=Hymenolepis diminuta OX... [more]
A0A3P9PHK62.177e-8542.98Uncharacterized protein OS=Poecilia reticulata OX=... [more]
I3JKF02.554e-8542.98Uncharacterized protein OS=Oreochromis niloticus O... [more]
A0A315US602.731e-8542.98Uncharacterized protein OS=Gambusia affinis OX=335... [more]
back to top
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000056663.11.740e-8441.67protein kinase cAMP-activated catalytic subunit be... [more]
prkacaa3.189e-8442.43cAMP-dependent protein kinase catalytic subunit al... [more]
prkacbb1.682e-8341.84cAMP-dependent protein kinase catalytic subunit be... [more]
prkacaa3.072e-8342.43cAMP-dependent protein kinase catalytic subunit al... [more]
ENSAMXT00000050353.13.943e-8342.26protein kinase cAMP-activated catalytic subunit be... [more]
back to top
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000001814.14.609e-7343.23pep scaffold:Pmarinus_7.0:GL481074:830:17391:1 gen... [more]
PRKCD3.579e-6239.02protein kinase C delta [Source:HGNC Symbol;Acc:HGN... [more]
ENSPMAT00000008480.11.273e-6139.01pep scaffold:Pmarinus_7.0:GL482122:191709:206473:1... [more]
ENSPMAT00000002200.11.666e-6139.19pep scaffold:Pmarinus_7.0:GL479132:31244:36905:-1 ... [more]
PRKCD1.566e-5238.60protein kinase C delta [Source:HGNC Symbol;Acc:HGN... [more]
back to top
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
TPK33.322e-7241.07cAMP-dependent protein kinase catalytic subunit; p... [more]
TPK12.179e-7039.53cAMP-dependent protein kinase catalytic subunit; p... [more]
TPK26.540e-6939.17cAMP-dependent protein kinase catalytic subunit; p... [more]
YPK13.020e-5838.27S/T protein kinase; phosphorylates, downregulates ... [more]
KIN828.926e-5738.38Putative serine/threonine protein kinase; implicat... [more]
back to top
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO352281.062e-7040.81Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO378004.223e-6034.81Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO411661.629e-5936.55Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO384073.764e-5638.25Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO318951.564e-5435.44Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000028912.13.775e-8743.14protein kinase cAMP-activated catalytic subunit be... [more]
ENSORLT00000035979.15.804e-8542.69cAMP-dependent protein kinase catalytic subunit be... [more]
ENSORLT00000033457.19.900e-8543.03cAMP-dependent protein kinase catalytic subunit be... [more]
ENSORLT00000007944.22.096e-8342.90protein kinase cAMP-activated catalytic subunit be... [more]
prkacaa3.227e-8342.14cAMP-dependent protein kinase catalytic subunit al... [more]
back to top
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000051702.10.000e+0100.00SMESG000051702.1[more]
SMESG000077092.11.743e-8445.27SMESG000077092.1[more]
SMESG000037955.15.169e-8448.85SMESG000037955.1[more]
SMESG000043218.14.032e-7944.09SMESG000043218.1[more]
SMESG000048623.16.244e-7943.03SMESG000048623.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30021427 ID=SMED30021427|Name=cAMP-dependent protein kinase catalytic subunit|organism=Schmidtea mediterranea sexual|type=transcript|length=1253bp
GATTTCCTATAATTATTTAGTAATCTATTTTTGAAAATTAATAATTATAA
ATTTAAAATATGCATAAGCCAATAGATAAAATTCCGCTTCGAGTAGAATC
GGATTTCCCTGGAATGTGGGATAAACTAACTTGGGAATTCCTCGGAAGAC
TTAAAGAAAATCCAGTTGATAGAAAGACAGCATGGGATGATTTTGAACAC
ATACGTATATTAGGAGAAGGAGGGTTTGGAAGAGTTATTTTAAGTAGACA
CAAATCGAAGAATCTATATGTTGCCCTGAAAATTATGGAAAAAGAAAAAA
TAATTAAAATGAAACAGATCCCGATTGTAATTGGAGAAAAGACTATTTTG
GCTTTATGCAAATTCCAATTTTTATTGAGACTATATACAACTTTTCAAAC
AAACGATAATATATGTTTCTGTTTGGAATTAGCCCCGGGTGGAGACTTAT
ATGGTGTCATAAAGCTATACTCACCTTTCGATATGCAAGCAATAAGATTT
TACAGCAGTCAAGTTTTATTAGGTCTTCAATATTTGCATACAATGAGAAT
CGTTTATAGAGATCTTAAACCTGAAAATATATTAATTGCAAATAATGGAT
ATATAAAACTTGCAGATATGGGATTTGCCAAATTTTTGCAAGATTCTCCA
CGGACATATACTTTTTGTGGGACACCAGAGTACATTGCACCGGAAGTAGT
TTTGAATAAAGGGTATGGAACAGCAGTTGACTGGTGGGCGTTTGGTGTTT
TAATTTATGAACTATTTTTCTCAACAACACCATTCTATTATACGGATCAA
ATTAAAATATTTAGAAATATTGTAAAAGGTAAATATAAAATACCACACGA
GCTTTCGATTGAAGCAAAAAGTTTAATAAAATATCTTCTTCAAATAGACT
GTACAAAGAGAATAGGAAATTTAAGAAACGGAGCGCTGGATGTAAGGTAT
CATCCGTTCTTCAAACTAATAGACTGGACAGATATGATGGGACAATTATT
AAAACCCCCTTTTCCTATTAAAAATCCAGATTATTCACAAATGAAAAAAG
ATGAAAAAATTGAAGAGATGAGAGATAAATCACTTACTTTGAAATACTTT
GAAGAATTTAAAAATTTTTAGTAAATCCTAGTTTATTAAATGGACAAGAT
ATTTCAAAGGCTCGAATGATATTATGGGTAAACAAACTCAATAAGAATTA
ATGATATAAACATCAAGTCCATCAATTTTTTAAAAATTTTGTTTGAAATT
TGC
back to top

protein sequence of SMED30021427-orf-1

>SMED30021427-orf-1 ID=SMED30021427-orf-1|Name=SMED30021427-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=354bp
MHKPIDKIPLRVESDFPGMWDKLTWEFLGRLKENPVDRKTAWDDFEHIRI
LGEGGFGRVILSRHKSKNLYVALKIMEKEKIIKMKQIPIVIGEKTILALC
KFQFLLRLYTTFQTNDNICFCLELAPGGDLYGVIKLYSPFDMQAIRFYSS
QVLLGLQYLHTMRIVYRDLKPENILIANNGYIKLADMGFAKFLQDSPRTY
TFCGTPEYIAPEVVLNKGYGTAVDWWAFGVLIYELFFSTTPFYYTDQIKI
FRNIVKGKYKIPHELSIEAKSLIKYLLQIDCTKRIGNLRNGALDVRYHPF
FKLIDWTDMMGQLLKPPFPIKNPDYSQMKKDEKIEEMRDKSLTLKYFEEF
KNF*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0004679AMP-activated protein kinase activity
GO:0004691cAMP-dependent protein kinase activity
GO:0034237protein kinase A regulatory subunit binding
GO:0004672protein kinase activity
GO:0005524ATP binding
GO:0000166nucleotide binding
GO:0004674protein serine/threonine kinase activity
GO:0016301kinase activity
GO:0016740transferase activity
Vocabulary: biological process
TermDefinition
GO:0007186G-protein coupled receptor signaling pathway
GO:0006468protein phosphorylation
GO:0016310phosphorylation
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0003304testis primordium
Vocabulary: INTERPRO
TermDefinition
IPR000719Prot_kinase_dom
IPR017441Protein_kinase_ATP_BS
IPR008271Ser/Thr_kinase_AS
IPR011009Kinase-like_dom_sf
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000719Protein kinase domainSMARTSM00220serkin_6coord: 45..301
e-value: 1.3E-88
score: 310.4
IPR000719Protein kinase domainPFAMPF00069Pkinasecoord: 45..301
e-value: 1.7E-66
score: 224.3
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 45..301
score: 45.361
NoneNo IPR availableGENE3DG3DSA:1.10.510.10coord: 129..321
e-value: 3.2E-102
score: 343.4
NoneNo IPR availableGENE3DG3DSA:3.30.200.20coord: 43..128
e-value: 3.2E-102
score: 343.4
NoneNo IPR availablePIRSFPIRSF000654ILKcoord: 30..285
e-value: 1.7E-23
score: 80.6
NoneNo IPR availablePANTHERPTHR24353:SF117PROTEIN KINASE CAMP-ACTIVATED CATALYTIC SUBUNIT BETAcoord: 33..343
NoneNo IPR availablePANTHERPTHR24353CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASEcoord: 33..343
IPR008271Serine/threonine-protein kinase, active sitePROSITEPS00108PROTEIN_KINASE_STcoord: 164..176
IPR017441Protein kinase, ATP binding sitePROSITEPS00107PROTEIN_KINASE_ATPcoord: 51..74
IPR011009Protein kinase-like domain superfamilySUPERFAMILYSSF56112Protein kinase-like (PK-like)coord: 33..325