general transcription factor IIE 1

Overview


Name	general transcription factor IIE 1 (AKG62104.1)
Smed ID	SMED30021388
Length (bp)	1263

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of general transcription factor IIE 1 (SMED30021388) t-SNE clustered cells

Violin plots show distribution of expression levels for general transcription factor IIE 1 (SMED30021388) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of general transcription factor IIE 1 (SMED30021388) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for general transcription factor IIE 1 (SMED30021388) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30021388

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
X1 cell	SMED30021388	SMESG000064941.1	SmedASXL_006341	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X2 cell	SMED30021388	SMESG000064941.1	SmedASXL_006341	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
neoblast	SMED30021388	SMESG000064941.1	dd_Smed_v4_8510_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of general transcription factor IIE 1 vs. Ensembl Human
Match: GTF2E1 (general transcription factor IIE subunit 1 [Source:HGNC Symbol;Acc:HGNC:4650])

HSP 1 Score: 116.316 bits (290), Expect = 6.033e-28
Identity = 75/298 (25.17%), Postives = 137/298 (45.97%), Query Frame = 2

Query:   32 TNIPADIQDMILAIPRVFYDATEGAILNFLIRYNYLSEQQLVEKSEFDFQMVRSSLNKLRKDKLVDMKMQVSTDENGKSINTSYFFINFKQALNCFMYRLESSYKKLEEAQRQNISSGDYCCTECGQTYSDLDIMSLFNFERDCILCGICNGVVESIEDKEKRHNAREEIARFNTKIRNPFVSLFEKCNKYLLTPDMIRPEFKDPNAANDSADNVKSNNA----------------NPNKVDEISVNLNSNATWGDTYNTAE---KEAKENPAWISSNVANNFISNINQSENNSDKNS 868
            T +PA ++ +   + R FY       L+ LIR + + E+ ++E  +FD + +RS LN L+ DK +  +M+V T  +GK+   +Y+FIN++  +N   Y+L+   +++E  +R + +   + C  C  T++DL+   LF+       C  C+  VE  E    + +AR  +ARFN +I  P  +L  +     L  +++ PE  +  A   S D+  +                    P+  D  + N+  N    +  + A    K AKE P W+  +       + +  E   D ++
Sbjct:    8 TEVPAALKRLAKYVIRGFYGIEHALALDILIRNSCVKEEDMLELLKFDRKQLRSVLNNLKGDKFIKCRMRVETAADGKTTRHNYYFINYRTLVNVVKYKLDHMRRRIETDERDSTNRASFKCPVCSSTFTDLEANQLFDPMTGTFRCTFCHTEVEEDESAMPKKDARTLLARFNEQI-EPIYALLRETEDVNLAYEILEPEPTEIPALKQSKDHAATTAGAASLAGGHHREAWATKGPSYEDLYTQNVVINMDDQEDLHRASLEGKSAKERPIWLRESTVQGAYGSEDMKEGGIDMDA 304

[Close]

BLAST of general transcription factor IIE 1 vs. Ensembl Human
Match: GTF2E1 (general transcription factor IIE subunit 1 [Source:HGNC Symbol;Acc:HGNC:4650])

HSP 1 Score: 73.9442 bits (180), Expect = 1.636e-15
Identity = 35/112 (31.25%), Postives = 66/112 (58.93%), Query Frame = 2

Query:   32 TNIPADIQDMILAIPRVFYDATEGAILNFLIRYNYLSEQQLVEKSEFDFQMVRSSLNKLRKDKLVDMKMQVSTDENGKSINTSYFFINFKQALNCFMYRLESSYKKLEEAQR 367
            T +PA ++ +   + R FY       L+ LIR + + E+ ++E  +FD + +RS LN L+ DK +  +M+V T  +GK+   +Y+FIN++  +N   Y+L+   +++E  +R
Sbjct:    8 TEVPAALKRLAKYVIRGFYGIEHALALDILIRNSCVKEEDMLELLKFDRKQLRSVLNNLKGDKFIKCRMRVETAADGKTTRHNYYFINYRTLVNVVKYKLDHMRRRIETDER 119

[Close]

BLAST of general transcription factor IIE 1 vs. Ensembl Celegans
Match: gtf-2E1 (General Transcription Factor homolog; TFIIE-alpha protein [Source:UniProtKB/TrEMBL;Acc:G5EG49])

HSP 1 Score: 93.9745 bits (232), Expect = 1.156e-20
Identity = 50/200 (25.00%), Postives = 101/200 (50.50%), Query Frame = 2

Query:   38 IPADIQDMILAIPRVFYDATEGAILNFLIRYNYLSEQQLVEKSEFDFQMVRSSLNKLRKDKLVDMKMQVSTDENGKSINTSYFFINFKQALNCFMYRLESSYKKLEEAQRQNISSGDYCCTECGQTYSDLDIMSLFNFERDCILCGICNGVVESIEDKEKRHNAREEIARFNTKIRNPFVSLFEKCNKYLLTPDMIRPEF 637
            IP  +  ++L + + F+ +    I+  ++R   + E+ L  + +FD +M+R  L  L+ +KLV  +     +EN ++++  +++IN++  LN   Y+++   +KLE  ++ + +   Y C  C  +Y  L+I  + + E   ++C  C+G V + E        R  +ARFN ++  P  S     N   L P ++ P+ 
Sbjct:   23 IPEALNTILLMVVKNFFSSEHFIIVYHIMRAQCIREENLKARIQFDQKMLRQLLASLKAEKLVKERTITQKNENNRTVSIIFYYINYRAVLNVVRYKIDHMRQKLESREQMDTNRAHYRCGACQSSYDMLEINRILDAESGRLICWRCHGDVLADETVVPSRTTRTAVARFNEQM-TPLFSHICALNGIQLAPHLLEPDI 221

[Close]

BLAST of general transcription factor IIE 1 vs. Ensembl Fly
Match: TfIIEalpha (gene:FBgn0015828 transcript:FBtr0076108)

HSP 1 Score: 111.694 bits (278), Expect = 9.025e-27
Identity = 69/273 (25.27%), Postives = 129/273 (47.25%), Query Frame = 2

Query:   32 TNIPADIQDMILAIPRVFYDATEGAILNFLIRYNYLSEQQLVEKSEFDFQMVRSSLNKLRKDKLVDMKMQVSTDENGKSINTSYFFINFKQALNCFMYRLESSYKKLEEAQRQNISSGDYCCTECGQTYSDLDIMSLFNFERDCILCGICNGVVESIEDKEKRHNAREEIARFNTKIRNPFVSLFEKCNKYLLTPDMIRPEFKD---------PNAANDSADNVKSNNANPNK---VDEISVNLNSNATWGDTYNTAEKEAKENPAWISSNVA 814
            T +P+ ++ +   + R FY   +  I++ L+R   + E  + E   F+ + +R+ +  LR DK + +++++ T  +GK+   +Y+FIN+K  +N   Y+L+   K++E  +R   S   + C+ C +T++DL+   LF+       C  C   VE       + ++R  +A FN +++ P   L  +     L P+++ PE  D         PNA         S  A  N+   V+E  V++      GD  + A  E K  P W++ +  
Sbjct:   22 TEVPSSLKQLARLVVRGFYSLEDALIIDMLVRNPCMKEDDIGELLRFEKKQLRARITTLRTDKFIQIRLKMETGPDGKAQKVNYYFINYKTFVNVVKYKLDLMRKRMETEERDATSRASFKCSSCSKTFTDLEADQLFDMATLEFRCTFCGSSVEEDSAAMPKKDSRLMLAHFNEQLQ-PLYDLLREVEGIKLAPEVLEPEPVDIDTIRGLNKPNATRPDG-MAWSGEATRNQGFAVEETRVDVT---IGGDDTSDAVIERKSRPIWMTESTV 289

[Close]

BLAST of general transcription factor IIE 1 vs. Ensembl Zebrafish
Match: gtf2e1 (general transcription factor IIE, polypeptide 1, alpha [Source:ZFIN;Acc:ZDB-GENE-041210-221])

HSP 1 Score: 112.464 bits (280), Expect = 7.491e-27
Identity = 61/201 (30.35%), Postives = 105/201 (52.24%), Query Frame = 2

Query:   32 TNIPADIQDMILAIPRVFYDATEGAILNFLIRYNYLSEQQLVEKSEFDFQMVRSSLNKLRKDKLVDMKMQVSTDENGKSINTSYFFINFKQALNCFMYRLESSYKKLEEAQRQNISSGDYCCTECGQTYSDLDIMSLFNFERDCILCGICNGVVESIEDKEKRHNAREEIARFNTKIRNPFVSLFEKCNKYLLTPDMIRPE 634
            T +PA ++ +   + R FY       L+ LIR   + E+ ++E  +FD + +RS LN L+ DK V  +M+V T  +GK+   +Y+FIN++  +N   Y+L+   +++E  +R + +   + C  C  T++DL+   LF+       C  C   VE  E    + +AR  +ARFN +I  P   L  +     L+ D++ PE
Sbjct:    8 TEVPASLKRLAKQVVRGFYGIEHALALDVLIRNPCVREEDMLELLKFDRKQLRSVLNTLKADKFVKCRMRVETAPDGKTTRHNYYFINYRLLVNVVKYKLDHMRRRIETDERDSTNRASFRCPCCTNTFTDLEANQLFDPMTGTFRCTFCQTEVEEDESAVPKKDARTLVARFNEQI-EPIYVLLRETENINLSHDLLEPE 207

[Close]

Query:   32 TNIPADIQDMILAIPRVFYDATEGAILNFLIRYNYLSEQQLVEKSEFDFQMVRSSLNKLRKDKLVDMKMQVSTDENGKSINTSYFFINFKQALNCFMYRLESSYKKLEEAQRQNISSGDYCCTECGQTYSDLDIMSLFNFERDCILCGICNGVVESIEDKEKRHNAREEIARFNTKIRNPFVSLFEKCNKYLLTPDMIRPE 634
            T +PA ++ +   + R FY       L+ LIR   + E+ ++E  +FD + +RS LN L+ DK V  +M+V T  +GK+   +Y+FIN++  +N   Y+L+   +++E  +R + +   + C  C  T++DL+   LF+       C  C   VE  E    + +AR  +ARFN +I  P   L  +     L+ D++ PE
Sbjct:    8 TEVPASLKRLAKQVVRGFYGIEHALALDVLIRNPCVREEDMLELLKFDRKQLRSVLNTLKADKFVKCRMRVETAPDGKTTRHNYYFINYRLLVNVVKYKLDHMRRRIETDERDSTNRASFRCPCCTNTFTDLEANQLFDPMTGTFRCTFCQTEVEEDESAVPKKDARTLVARFNEQI-EPIYVLLRETENINLSHDLLEPE 207

[Close]

Query:   32 TNIPADIQDMILAIPRVFYDATEGAILNFLIRYNYLSEQQLVEKSEFDFQMVRSSLNKLRKDKLVDMKMQVSTDENGKSINTSYFFINFKQALNCFMYRLESSYKKLEEAQRQNISSGDYCCTECGQTYSDLDIMSLFNFERDCILCGICNGVVESIEDKEKRHNAREEIARFNTKIRNPFVSLFEKCNKYLLTPDMIRPE 634
            T +PA ++ +   + R FY       L+ LIR   + E+ ++E  +FD + +RS LN L+ DK V  +M+V T  +GK+   +Y+FIN++  +N   Y+L+   +++E  +R + +   + C  C  T++DL+   LF+       C  C   VE  E    + +AR  +ARFN +I  P   L  +     L+ D++ PE
Sbjct:    8 TEVPASLKRLAKQVVRGFYGIEHALALDVLIRNPCVREEDMLELLKFDRKQLRSVLNTLKADKFVKCRMRVETAPDGKTTRHNYYFINYRLLVNVVKYKLDHMRRRIETDERDSTNRASFRCPCCTNTFTDLEANQLFDPMTGTFRCTFCQTEVEEDESAVPKKDARTLVARFNEQI-EPIYVLLRETENINLSHDLLEPE 207

[Close]

Query:   32 TNIPADIQDMILAIPRVFYDATEGAILNFLIRYNYLSEQQLVEKSEFDFQMVRSSLNKLRKDKLVDMKMQVSTDENGKSINTSYFFINFKQALNCFMYRLESSYKKLEEAQRQNISSGDYCCTECGQTYSDLDIMSLFNFERDCILCGICNGVVESIEDKEKRHNAREEIARFNTKIRNPFVSLFEKCNKYLLTPDMIRPE 634
            T +PA ++ +   + R FY       L+ LIR   + E+ ++E  +FD + +RS LN L+ DK V  +M+V T  +GK+   +Y+FIN++  +N   Y+L+   +++E  +R + +   + C  C  T++DL+   LF+       C  C   VE  E    + +AR  +ARFN +I  P   L  +     L+ D++ PE
Sbjct:    8 TEVPASLKRLAKQVVRGFYGIEHALALDVLIRNPCVREEDMLELLKFDRKQLRSVLNTLKADKFVKCRMRVETAPDGKTTRHNYYFINYRLLVNVVKYKLDHMRRRIETDERDSTNRASFRCPCCTNTFTDLEANQLFDPMTGTFRCTFCQTEVEEDESAVPKKDARTLVARFNEQI-EPIYVLLRETENINLSHDLLEPE 207

[Close]

BLAST of general transcription factor IIE 1 vs. Ensembl Zebrafish
Match: gtf2e1 (general transcription factor IIE, polypeptide 1, alpha [Source:ZFIN;Acc:ZDB-GENE-041210-221])

HSP 1 Score: 64.6994 bits (156), Expect = 1.238e-12
Identity = 32/93 (34.41%), Postives = 54/93 (58.06%), Query Frame = 2

Query:   23 EKRTNIPADIQDMILAIPRVFYDATEGAILNFLIRYNYLSEQQLVEKSEFDFQMVRSSLNKLRKDKLVDMKMQVSTDENGKSINTSYFFINFK 301
            E  T +PA ++ +   + R FY       L+ LIR   + E+ ++E  +FD + +RS LN L+ DK V  +M+V T  +GK+   +Y+FIN++
Sbjct:    5 ELLTEVPASLKRLAKQVVRGFYGIEHALALDVLIRNPCVREEDMLELLKFDRKQLRSVLNTLKADKFVKCRMRVETAPDGKTTRHNYYFINYR 97

[Close]

BLAST of general transcription factor IIE 1 vs. Ensembl Xenopus
Match: npbwr1 (neuropeptides B/W receptor 1 [Source:Xenbase;Acc:XB-GENE-984596])

HSP 1 Score: 110.923 bits (276), Expect = 3.084e-26
Identity = 62/204 (30.39%), Postives = 108/204 (52.94%), Query Frame = 2

Query:   23 EKRTNIPADIQDMILAIPRVFYDATEGAILNFLIRYNYLSEQQLVEKSEFDFQMVRSSLNKLRKDKLVDMKMQVSTDENGKSINTSYFFINFKQALNCFMYRLESSYKKLEEAQRQNISSGDYCCTECGQTYSDLDIMSLFNFERDCILCGICNGVVESIEDKEKRHNAREEIARFNTKIRNPFVSLFEKCNKYLLTPDMIRPE 634
            E  T +PA ++ +   + R FY       L+ LIRY  + E  +    +F+ + +R+ LN L+ DK +  +M+V T  NGKS   +Y++IN+K  ++   Y+L+   +K+E  +R + +   + C  C  TYSDL++  LF+   +   C  CN  VE       + +AR  +ARFN +I   FV L ++    +L  +++ P+
Sbjct:    5 ETMTEVPAALKRLAKYMVRGFYGLEYSLTLDVLIRYPCVKEDDIGLLLKFEKKQLRTILNTLKADKFIKCRMRVETGPNGKSTRHNYYYINYKVLVDVVKYKLDHVRRKIESDERDSTTRASFKCPGCLSTYSDLEVNQLFDPFTELFRCTYCNVEVEEDSSSLPKRDARTLLARFNEQIEPIFV-LLQETEDIILPCELLEPQ 207

[Close]

BLAST of general transcription factor IIE 1 vs. Ensembl Xenopus
Match: mgc89226 (mgc89226 protein [Source:Xenbase;Acc:XB-GENE-5804925])

HSP 1 Score: 107.071 bits (266), Expect = 9.148e-25
Identity = 58/201 (28.86%), Postives = 104/201 (51.74%), Query Frame = 2

Query:   32 TNIPADIQDMILAIPRVFYDATEGAILNFLIRYNYLSEQQLVEKSEFDFQMVRSSLNKLRKDKLVDMKMQVSTDENGKSINTSYFFINFKQALNCFMYRLESSYKKLEEAQRQNISSGDYCCTECGQTYSDLDIMSLFNFERDCILCGICNGVVESIEDKEKRHNAREEIARFNTKIRNPFVSLFEKCNKYLLTPDMIRPE 634
            T +PA ++ +   + R FY       L+ LIR   + E  ++E  +FD + +R+ LN L+ DK +  +M+V T  +GK+   +Y+FIN++  +N   Y+L+   +++E  +R + +   + C  C  T++DL+   LF+       C  C   VE  E    + +AR  +ARFN +I  P  +L  +     L  +++ PE
Sbjct:    8 TEVPAVLKRLAKYVVRGFYGLEHALALDILIRNPCVKEDDMMELLKFDRKQLRAVLNTLKGDKFIKCRMRVETATDGKTTRHNYYFINYRLLVNVVKYKLDHMRRRIETDERDSTNRASFKCPNCCSTFTDLEANQLFDPMTGMFRCTFCQTEVEEDESAMPKKDARTLVARFNEQI-EPIYALLRETEDINLAYEILEPE 207

[Close]

BLAST of general transcription factor IIE 1 vs. Ensembl Mouse
Match: Gtf2e1 (general transcription factor II E, polypeptide 1 (alpha subunit) [Source:MGI Symbol;Acc:MGI:1921447])

HSP 1 Score: 113.235 bits (282), Expect = 4.163e-27
Identity = 77/298 (25.84%), Postives = 135/298 (45.30%), Query Frame = 2

Query:   32 TNIPADIQDMILAIPRVFYDATEGAILNFLIRYNYLSEQQLVEKSEFDFQMVRSSLNKLRKDKLVDMKMQVSTDENGKSINTSYFFINFKQALNCFMYRLESSYKKLEEAQRQNISSGDYCCTECGQTYSDLDIMSLFNFERDCILCGICNGVVESIEDKEKRHNAREEIARFNTKIRNPFVSLFEKCNKYLLTPDMIRPEFKDPNAANDSADNVKS----------------NNANPNKVDEISVNLNSNATWGDTYNTAE---KEAKENPAWISSNVANNFISNINQSENNSDKNS 868
            T +PA ++ +   + R FY       L+ LIR   + E+ ++E  +FD + +RS LN L+ DK +  +M+V T  +GK+   +Y+FIN++  +N   Y+L+   +++E  +R + +   + C  C  T++DL+   LF+       C  C+  VE  E    + +AR  +ARFN +I  P  +L  +     L  +++ PE  +  A   S D   +                 N  P+  D  + N+  N    D  +      K AKE P W+  +      S+    E   D ++
Sbjct:    8 TEVPAALKRLAKYVIRGFYGIEHVLALDILIRNPCVKEEDMLELLKFDRKQLRSVLNNLKGDKFIKCRMRVETAADGKTTRHNYYFINYRTLVNVVKYKLDHMRRRIETDERNSTNRASFKCPVCCSTFTDLEANQLFDPMTGTFRCTFCHTEVEEDESAMPKKDARTLLARFNEQI-EPIYALLRETEDVNLAYEILEPEPTEIPALKQSKDRAATAAGAAGLAGGHHREAWTNKGPSYEDLYTQNVVINMDDQDDVHRPSLEGKAAKERPIWLRESTVQGAYSSEEMKEGGIDVDT 304

[Close]

BLAST of general transcription factor IIE 1 vs. UniProt/SwissProt
Match: sp|Q5R8H5|T2EA_PONAB (General transcription factor IIE subunit 1 OS=Pongo abelii OX=9601 GN=GTF2E1 PE=2 SV=1)

HSP 1 Score: 117.087 bits (292), Expect = 1.366e-27
Identity = 76/298 (25.50%), Postives = 137/298 (45.97%), Query Frame = 2

Query:   32 TNIPADIQDMILAIPRVFYDATEGAILNFLIRYNYLSEQQLVEKSEFDFQMVRSSLNKLRKDKLVDMKMQVSTDENGKSINTSYFFINFKQALNCFMYRLESSYKKLEEAQRQNISSGDYCCTECGQTYSDLDIMSLFNFERDCILCGICNGVVESIEDKEKRHNAREEIARFNTKIRNPFVSLFEKCNKYLLTPDMIRPEFKDPNAANDSADNVKSNNA----------------NPNKVDEISVNLNSNATWGDTYNTAE---KEAKENPAWISSNVANNFISNINQSENNSDKNS 868
            T +PA ++ +   + R FY       L+ LIR   + E+ ++E  +FD + +RS LN L+ DK +  +M+V T  +GK+   +Y+FIN++  +N   Y+L+   +++E  +R + +   + C  C  T++DL+   LF+       C  C+  VE  E    + +AR  +ARFN +I  P  +L  +     L  +++ PE  +  A   S D+  +                    P+  D  + N+  N    +  + A    K AKE P W+  +      S+ +  E   D ++
Sbjct:    8 TEVPAALKRLAKYVIRGFYGIEHALALDILIRNPCVKEEDMLELLKFDRKQLRSVLNNLKGDKFIKCRMRVETAADGKTTRHNYYFINYRTLVNVVKYKLDHMRRRIETDERDSTNRASFKCPVCSSTFTDLEANQLFDPMTGTFRCTFCHTEVEEDESAMPKKDARTLLARFNEQI-EPIYALLRETEDVNLAYEILEPEPTEIPALKQSKDHAATTAGAASLAGGHHREAWATKGPSYEDLYTQNVVINMDDHEDLHRASLEGKSAKERPIWLRESTVQGAYSSEDMKEGGIDMDA 304

[Close]

BLAST of general transcription factor IIE 1 vs. UniProt/SwissProt
Match: sp|P29083|T2EA_HUMAN (General transcription factor IIE subunit 1 OS=Homo sapiens OX=9606 GN=GTF2E1 PE=1 SV=2)

HSP 1 Score: 116.316 bits (290), Expect = 2.897e-27
Identity = 75/298 (25.17%), Postives = 137/298 (45.97%), Query Frame = 2

Query:   32 TNIPADIQDMILAIPRVFYDATEGAILNFLIRYNYLSEQQLVEKSEFDFQMVRSSLNKLRKDKLVDMKMQVSTDENGKSINTSYFFINFKQALNCFMYRLESSYKKLEEAQRQNISSGDYCCTECGQTYSDLDIMSLFNFERDCILCGICNGVVESIEDKEKRHNAREEIARFNTKIRNPFVSLFEKCNKYLLTPDMIRPEFKDPNAANDSADNVKSNNA----------------NPNKVDEISVNLNSNATWGDTYNTAE---KEAKENPAWISSNVANNFISNINQSENNSDKNS 868
            T +PA ++ +   + R FY       L+ LIR + + E+ ++E  +FD + +RS LN L+ DK +  +M+V T  +GK+   +Y+FIN++  +N   Y+L+   +++E  +R + +   + C  C  T++DL+   LF+       C  C+  VE  E    + +AR  +ARFN +I  P  +L  +     L  +++ PE  +  A   S D+  +                    P+  D  + N+  N    +  + A    K AKE P W+  +       + +  E   D ++
Sbjct:    8 TEVPAALKRLAKYVIRGFYGIEHALALDILIRNSCVKEEDMLELLKFDRKQLRSVLNNLKGDKFIKCRMRVETAADGKTTRHNYYFINYRTLVNVVKYKLDHMRRRIETDERDSTNRASFKCPVCSSTFTDLEANQLFDPMTGTFRCTFCHTEVEEDESAMPKKDARTLLARFNEQI-EPIYALLRETEDVNLAYEILEPEPTEIPALKQSKDHAATTAGAASLAGGHHREAWATKGPSYEDLYTQNVVINMDDQEDLHRASLEGKSAKERPIWLRESTVQGAYGSEDMKEGGIDMDA 304

[Close]

BLAST of general transcription factor IIE 1 vs. UniProt/SwissProt
Match: sp|Q9D0D5|T2EA_MOUSE (General transcription factor IIE subunit 1 OS=Mus musculus OX=10090 GN=Gtf2e1 PE=1 SV=1)

HSP 1 Score: 113.235 bits (282), Expect = 2.912e-26
Identity = 77/298 (25.84%), Postives = 135/298 (45.30%), Query Frame = 2

Query:   32 TNIPADIQDMILAIPRVFYDATEGAILNFLIRYNYLSEQQLVEKSEFDFQMVRSSLNKLRKDKLVDMKMQVSTDENGKSINTSYFFINFKQALNCFMYRLESSYKKLEEAQRQNISSGDYCCTECGQTYSDLDIMSLFNFERDCILCGICNGVVESIEDKEKRHNAREEIARFNTKIRNPFVSLFEKCNKYLLTPDMIRPEFKDPNAANDSADNVKS----------------NNANPNKVDEISVNLNSNATWGDTYNTAE---KEAKENPAWISSNVANNFISNINQSENNSDKNS 868
            T +PA ++ +   + R FY       L+ LIR   + E+ ++E  +FD + +RS LN L+ DK +  +M+V T  +GK+   +Y+FIN++  +N   Y+L+   +++E  +R + +   + C  C  T++DL+   LF+       C  C+  VE  E    + +AR  +ARFN +I  P  +L  +     L  +++ PE  +  A   S D   +                 N  P+  D  + N+  N    D  +      K AKE P W+  +      S+    E   D ++
Sbjct:    8 TEVPAALKRLAKYVIRGFYGIEHVLALDILIRNPCVKEEDMLELLKFDRKQLRSVLNNLKGDKFIKCRMRVETAADGKTTRHNYYFINYRTLVNVVKYKLDHMRRRIETDERNSTNRASFKCPVCCSTFTDLEANQLFDPMTGTFRCTFCHTEVEEDESAMPKKDARTLLARFNEQI-EPIYALLRETEDVNLAYEILEPEPTEIPALKQSKDRAATAAGAAGLAGGHHREAWTNKGPSYEDLYTQNVVINMDDQDDVHRPSLEGKAAKERPIWLRESTVQGAYSSEEMKEGGIDVDT 304

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BLAST of general transcription factor IIE 1 vs. UniProt/SwissProt
Match: sp|A6QLI8|T2EA_BOVIN (General transcription factor IIE subunit 1 OS=Bos taurus OX=9913 GN=GTF2E1 PE=2 SV=1)

HSP 1 Score: 112.464 bits (280), Expect = 5.623e-26
Identity = 76/298 (25.50%), Postives = 134/298 (44.97%), Query Frame = 2

Query:   32 TNIPADIQDMILAIPRVFYDATEGAILNFLIRYNYLSEQQLVEKSEFDFQMVRSSLNKLRKDKLVDMKMQVSTDENGKSINTSYFFINFKQALNCFMYRLESSYKKLEEAQRQNISSGDYCCTECGQTYSDLDIMSLFNFERDCILCGICNGVVESIEDKEKRHNAREEIARFNTKIRNPFVSLFEKCNKYLLTPDMIRPEFKDPNAANDSADNVKS----------------NNANPNKVDEISVNLNSNATWGDTYNTAE---KEAKENPAWISSNVANNFISNINQSENNSDKNS 868
            T +PA ++ +   + R FY       L+ LIR   + E+ ++E  +FD + +RS LN L+ DK +  +M+V T  +GK+   +Y+FIN++  +N   Y+L+   +++E  +R + +   + C  C  T++DL+   LF+       C  C   VE  E    + +AR  +ARFN +I  P  +L  +     L  +++ PE  +  A   S D   +                    P+  D  + N+  N    +  + A    K AKE P W+  +      ++    E   D +S
Sbjct:    8 TEVPAALKRLAKYVIRGFYGIEHALALDILIRNPCVKEEDMLELLKFDRKQLRSVLNNLKGDKFIKCRMRVETAADGKTTRHNYYFINYRTLVNVVKYKLDHMRRRIETDERDSTNRASFKCPVCSSTFTDLEANQLFDPMTGTFRCTFCQTEVEEDESAMPKKDARTLLARFNEQI-EPIYALLRETEDVNLAYEILEPEPTEIPALKQSKDRAATAAGAAGLAGGHHREAWTTKGPSYEDLYTQNVVINMDDQEDLHRASLEGKSAKERPIWLRESTVQGAYNSEEMKEGGIDIDS 304

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BLAST of general transcription factor IIE 1 vs. UniProt/SwissProt
Match: sp|Q9P3W1|T2EA_SCHPO (Transcription initiation factor IIE subunit alpha OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=tfa1 PE=1 SV=3)

HSP 1 Score: 73.559 bits (179), Expect = 7.073e-13
Identity = 40/178 (22.47%), Postives = 89/178 (50.00%), Query Frame = 2

Query:   32 TNIPADIQDMILAIPRVFYDATEGAILNFLIRYNYLSEQQLVEKSEFDFQMVRSSLNKLRKDKLVDMKMQVSTDENG-KSINTSYFFINFKQALNCFMYRLESSYKKLEEAQRQNISSGDYCCTECGQTYSDLDIMSLFNFERDCILCGICNGVVESIEDKEKRHNAREEIARFNTKI 562
            +N P  +Q +I  I R FY+      ++ ++R++ L+++Q         +  R    KLR+D+L+ ++ +    E   +  +T+YF+I+F   ++   +R+    K +E+  R +  S  Y C  C + +S LD++SL   E     C +C   ++  E+  +  ++++ + +   ++
Sbjct:    2 SNAPEIVQRLIKMIMRAFYETRHIIFMDAILRHSALTDEQTALLMGIPIKECRFIAGKLREDRLLAIQSRTEMKEGQQRQYHTTYFYIDFCSTIDSIKWRMHQLVKTVEDRMRNDFDSKGYVCPFCNKKFSSLDVLSLVTNE-GTFACNVCGTELKDDEESAEMMSSQKRLGKLMGQV 178

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BLAST of general transcription factor IIE 1 vs. TrEMBL
Match: A0A0F7CYH0 (General transcription factor IIE 1 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 590.882 bits (1522), Expect = 0.000e+0
Identity = 282/284 (99.30%), Postives = 284/284 (100.00%), Query Frame = 2

Query:  362 QRQNISSGDYCCTECGQTYSDLDIMSLFNFERDCILCGICNGVVESIEDKEKRHNAREEIARFNTKIRNPFVSLFEKCNKYLLTPDMIRPEFKDPNAANDSADNVKSNNANPNKVDEISVNLNSNATWGDTYNTAEKEAKENPAWISSNVANNFISNINQSENNSDKNSSAQADNITLTMAPGRVPGAITTVNSSMPVADIMSVLLANEYCVENSIKFYENLRKDLHYKPLQSNLFKVLVNGASYDIWNVTEEMFERMTKEEIIQFKSLGRRLHDYCYDSMYIC 1213
            +RQNISSGDYCCTECGQTYSDLDIMSLFNFERDCILCGICNGVVESIEDKEKRHNAREEIARFNTKIRNPFVSLFEKCNKYLLTPDMIRPEFKDPNAANDSADNVKSNNANPNKVDEISVNLNSNATWGDTYNTAEKEAKENPAWISSNVANNFISNINQSENNSDKNSSAQADNITLTMAPGRVPGAITTVNSSMPVADIMSVLLANEYCVENSIKFYENLRKDLHYKPLQSNLFKVLVNGASYDIWNVTEEMFERMTKEE+IQFKSLGRRLHDYCYDSMYIC
Sbjct:   11 KRQNISSGDYCCTECGQTYSDLDIMSLFNFERDCILCGICNGVVESIEDKEKRHNAREEIARFNTKIRNPFVSLFEKCNKYLLTPDMIRPEFKDPNAANDSADNVKSNNANPNKVDEISVNLNSNATWGDTYNTAEKEAKENPAWISSNVANNFISNINQSENNSDKNSSAQADNITLTMAPGRVPGAITTVNSSMPVADIMSVLLANEYCVENSIKFYENLRKDLHYKPLQSNLFKVLVNGASYDIWNVTEEMFERMTKEEMIQFKSLGRRLHDYCYDSMYIC 294

[Close]

BLAST of general transcription factor IIE 1 vs. TrEMBL
Match: A0A0R3VUT7 (HTH TFE/IIEalpha-type domain-containing protein OS=Taenia asiatica OX=60517 GN=TASK_LOCUS1112 PE=4 SV=1)

HSP 1 Score: 160.614 bits (405), Expect = 1.115e-40
Identity = 88/320 (27.50%), Postives = 161/320 (50.31%), Query Frame = 2

Query:   29 RTNIPADIQDMILAIPRVFYDATEGAILNFLIRYNYLSEQQLVEKSEFDFQMVRSSLNKLRKDKLVDMKMQVSTDENGKSINTSYFFINFKQALNCFMYRLESSYKKLEEAQRQNISSGDYCCTECGQTYSDLDIMSLFNFERDCILCGICNGVVESIEDKEKRHNAREEIARFNTKIRNPFVSLFEKCNKYLLTPDMIRPEFK--DPNAANDSADNVKSNNANPNKVDEISVNLNSNATWGDTYNTAE-----------KEAKENPAWIS-SNVANNFISNINQSENNSDKNSSAQADNITLTMAPGRVPGAITTVNSS 946
            +T +P  ++ ++  I R FY      I++ L+R   + E  L E+  F+ + +R  L+ L+ D+ +  K+Q+ TD  G+     ++FI++K  +N   YRL+   ++LE  QRQ  S   Y C  C   Y+DL +  L + + D ++C  C   V+  ED  +R +AR  +A+F+ ++R P  +L ++C++  L+  ++ PEF+  +P     S  +  SN A+    +    + N N     T +T                KE P W+S S + +   + + + +     + S+ +D+ T T+APGRVP ++   +SS
Sbjct:   20 QTELPICLKRLVRTIVRSFYSREHSLIIDLLVRNTIMKEDDLCERLRFEKKQLRQHLHTLKTDQFIKSKLQLETDTEGRIAKIIHYFIDYKVFVNIVKYRLDQMQRRLETEQRQTSSRPLYRCLSCNSAYTDLQVDRLLSSQNDTLICVYCRAEVKEEEDNAQRSDARALVAKFHQQVRGPLDTLLKECDQVHLSSSILEPEFRALEPLPGTKSETDASSNAADSRAANSWLTDSNKNLMATSTESTVTIVLDAPTSSNVTAPKERPIWMSESTIDSGLGAGLGELDRGPTNDPSSASDSTTQTLAPGRVPTSLLDPSSS 339

[Close]

BLAST of general transcription factor IIE 1 vs. TrEMBL
Match: A0A0R3WJ21 (HTH TFE/IIEalpha-type domain-containing protein OS=Hydatigena taeniaeformis OX=6205 GN=TTAC_LOCUS647 PE=4 SV=1)

HSP 1 Score: 154.451 bits (389), Expect = 2.608e-38
Identity = 91/327 (27.83%), Postives = 164/327 (50.15%), Query Frame = 2

Query:   29 RTNIPADIQDMILAIPRVFYDATEGAILNFLIRYNYLSEQQLVEKSEFDFQMVRSSLNKLRKDKLVDMKMQVSTDENGKSINTSYFFINFKQALNCFMYRLESSYKKLEEAQRQNISSGDYCCTECGQTYSDLDIMSLFNFERDCILCGICNGVVESIEDKEKRHNAREEIARFNTKIRNPFVSLFEKCNKYLLTPDMIRPEFK--DP------------NAANDSADNVKSNNANPNKV---DEISVNLNSNATWGDTYNTAEKEAKENPAWIS-SNVANNFISNINQSENNSDKNSSAQADNITLTMAPGRVPGAITTVNSSMPV 955
            +T +P  ++ ++  I R FY      I++ L+R   + E  L E+  F+ + +R  L+ L+ D+ +  K+Q+ TD  GK     ++FI++K  +N   YRL+   ++LE  QRQ  S   + C  C   Y+DL++  L +     ++C  C   V+  ED  +R +AR  +A+F+ ++R P  +L ++C++  L+  ++ PEF+  +P            NA +  A N   N++N N V    E +V +  +A    +        KE P W+S S + +   + + + +     + S+ +D  T T+APGRVP ++    SS P 
Sbjct:   20 QTELPLCLKRLVRTIVRSFYSREHSLIIDLLVRNTIMKEDDLCERLRFEKKQLRQHLHTLKTDQFIKSKLQLETDTEGKIAKIIHYFIDYKVFVNIVKYRLDQMQRRLEAEQRQTSSRALFRCFSCNSAYTDLEVDRLLDPLTGSLVCVYCRAEVKEEEDNAQRSDARALVAKFHQQVRGPLDTLLKECDQVHLSSSILEPEFRALEPLPGTKSETDASSNAVDTRAANSWLNDSNKNPVATSTESTVTIVLDAPISSSVTA----PKERPIWMSESTIDSGLGAGLGELDRGPTSDPSSGSDLTTQTLAPGRVPTSLLDPTSSNPA 342

[Close]

BLAST of general transcription factor IIE 1 vs. TrEMBL
Match: A0A3Q0KU55 (Putative transcription initiation factor IIE, alpha subunit OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 154.836 bits (390), Expect = 2.743e-38
Identity = 120/461 (26.03%), Postives = 204/461 (44.25%), Query Frame = 2

Query:   32 TNIPADIQDMILAIPRVFYDATEGAILNFLIRYNYLSEQQLVEKSEFDFQMVRSSLNKLRKDKLVDMKMQVSTDENGKSINTSYFFINFKQALNCFMYRLESSYKKLEEAQRQNISSGDYCCTECGQTYSDLDIMSLFNFERDC-ILCGICNGVVESIEDKEKRHNAREEIARFNTKIRNPFVSLFEKCNKYLLTPDMIRPEFKDPNAANDSADN---VKSNNANPNKVDEISVNLNSNATWGDTYNTAE-----------KEAKENPAWIS-SNVANNFISNINQSENNSDKNSSAQ--------ADNITLTMAPGRVP------------GAI-------------------TTVNSSMPVADIMSVLLANE---YCVENSIK----------------------FYENLRKDLHYKPLQSNLFKVLVNGASYDIWNVTEEMFERMTKEEIIQFKSLGR 1174
            T +P  +  ++ +I R FY      I++ L+R   + E  L E+  F+ + +R  L+ L+ D+ +  K+Q+ TD +GK+   +++FI++K  +N   YRL+   ++LE  QRQ+ S   + C+ C   Y+DL++  L +F     ++C  C G V   ED   R +AR  IA+F+ ++R+P   +  +C++  L+P ++ PE +     ND   +     S N   N +     N  +++ +G T ++             +  KE P W+S S ++ N    I  +++  +  S+A          D IT T+APGRVP            G++                   T+   +   +DIM +LL +E       NS K                        EN   DLH K      F+V V G      +VT  M + MTKEE   +  +G+
Sbjct:   49 TKVPLCLIKLVRSIVRTFYSREHSLIVDMLVRNTIMKEDDLCERLRFERKQLRQYLHTLKCDQFIKSKLQLETDVDGKTTKITHYFIDYKLFVNVVKYRLDQMQRRLEAEQRQSTSRASFKCSSCNTAYTDLEVDRLMDFTNPGKLVCVYCRGEVCEEEDNASRTDARALIAKFHHQVRDPIDLMLRECDEIHLSPAILEPEIRPLEPLNDDTSDESQTSSQNVGRNSILSGDKNNKNSSLFGSTESSVRIVLSGNSSGSNQVVKERPIWMSDSTISLNPAPGIGDTDSQVNIFSNASEFHANHTPEDAITQTLAPGRVPSGFGSNLSNSVIGSVSHNRLADTTTSETNLMTNTTSGTHTASSSDIMQLLLVHERRSLLTRNSAKNASVPGRNNAHKTTLAQPDPLVNTENTSGDLHPKK-----FEVTVGGQLMLYTDVTPAMVKTMTKEERENYVRVGK 504

[Close]

BLAST of general transcription factor IIE 1 vs. TrEMBL
Match: A0A430Q3S6 (Transcription initiation factor TFIIE subunit alpha OS=Schistosoma bovis OX=6184 GN=DC041_0008289 PE=4 SV=1)

HSP 1 Score: 152.91 bits (385), Expect = 6.515e-38
Identity = 110/414 (26.57%), Postives = 197/414 (47.58%), Query Frame = 2

Query:   32 TNIPADIQDMILAIPRVFYDATEGAILNFLIRYNYLSEQQLVEKSEFDFQMVRSSLNKLRKDKLVDMKMQVSTDENGKSINTSYFFINFKQALNCFMYRLESSYKKLEEAQRQNISSGDYCCTECGQTYSDLDIMSLFNFERDC-ILCGICNGVVESIEDKEKRHNAREEIARFNTKIRNPFVSLFEKCNKYLLTPDMIRPEFKDPNAANDSADNVKSNNANPNKVDEISVNLNSNATWGDTYNTAE-----------KEAKENPAWIS----------SNVANNFISNINQSENN------SDKNSSAQADNITLTMAPGRVPGAITTVNSSMPVA-----DIMSVLLANEYCVENSIKFYENLRKDLHYKPLQSNLFKVLVNGASYDIWNVTEEMFERMTKEEIIQFKSLGR 1174
            T +P  +  ++ +I R FY      I++ L+R   + E  L E+  F+ + +R  L+ L+ D+ +  K+Q+ TD +GK+   +++FI++K  +N   YRL+   ++LE  QRQ+ S   + C+ C   Y+DL++  L +F     ++C  C G V   ED   R +AR  IA+F+ ++R+P   +  +C++  L+P ++ PE +     ND   + +S N   N +     N  +++ +G T ++             +  KE P W+S           N ++N +++   SE N         N+++ +D + L +   R    + T NS+  V+     +     LA    + N+    EN   DLH K      F+V V G      +VT  M + MTKEE   +  +G+
Sbjct:   49 TKVPICLIKLVRSIVRTFYSREHSLIVDMLVRNTIMKEDDLCERLRFERKQLRQYLHTLKCDQFIKSKLQLETDVDGKTTKITHYFIDYKLFVNVVKYRLDQMQRRLEAEQRQSTSRASFKCSSCNTAYTDLEVDRLMDFTNPGKLVCVYCRGEVCEEEDNASRTDARALIAKFHHQVRDPIDLMLRECDEIHLSPSILEPEIRPLEPLNDDTSD-ESQNIGRNSILPGDKNKKNSSLFGPTESSVRIVLSGNSSGSNQVVKERPIWMSDSTISLNPTPGNASHNRLADTTTSETNLMTNTTGGTNAASSSDIMQLLLVHER--RGLLTRNSAKNVSVPGRNNAHKTTLAQPDPLVNT----ENTSVDLHSKK-----FEVTVGGQLMLYTDVTPAMVKTMTKEERENYVRVGK 450

[Close]

BLAST of general transcription factor IIE 1 vs. Ensembl Cavefish
Match: gtf2e1 (general transcription factor IIE subunit 1 [Source:NCBI gene;Acc:103033262])

HSP 1 Score: 115.161 bits (287), Expect = 6.767e-28
Identity = 74/280 (26.43%), Postives = 131/280 (46.79%), Query Frame = 2

Query:   32 TNIPADIQDMILAIPRVFYDATEGAILNFLIRYNYLSEQQLVEKSEFDFQMVRSSLNKLRKDKLVDMKMQVSTDENGKSINTSYFFINFKQALNCFMYRLESSYKKLEEAQRQNISSGDYCCTECGQTYSDLDIMSLFNFERDCILCGICNGVVESIEDKEKRHNAREEIARFNTKIRNPFVSLFEKCNKYLLTPDMIRPEFKDPNAANDSADNVKSNNANPNKVDEISVNLNSNATWGDTY------NTAEKEA----------KENPAWISSNVANNF 823
            T +PA ++ +   + R FY       L+ LIR   + E+ ++E  +FD + +RS LN L+ DK V  +M+V T  +GK+   +Y+FIN++  +N   Y+L+   +++E  +R + +   + C  C  T++DL+   LF+       C  C   VE  E    + +AR  +ARFN +I  P   L  +     L+ D++ PE  +  A   S +    +      +    V     +++GD Y      N  E+E+          KE P W++ +    +
Sbjct:    8 TEVPASLKRLAKQVVRGFYGIEHALALDVLIRNPCVREEDMLELLKFDRKQLRSVLNTLKGDKFVKCRMRVETAPDGKTTRHNYYFINYRLLVNVVKYKLDHIRRRIETDERDSTNRASFRCPCCHNTFTDLEANQLFDPMTGTFRCTFCQTEVEEDESAVPKKDARTLVARFNEQI-EPIYVLLRETEDINLSHDLLEPEPTEIPALKQSRERAAPSGGAGAGMPGRDV-WKKGSSYGDLYTQNVVINMDEQESQGQAAEAKAPKERPVWLTESTVEPY 285

[Close]

Query:   32 TNIPADIQDMILAIPRVFYDATEGAILNFLIRYNYLSEQQLVEKSEFDFQMVRSSLNKLRKDKLVDMKMQVSTDENGKSINTSYFFINFKQALNCFMYRLESSYKKLEEAQRQNISSGDYCCTECGQTYSDLDIMSLFNFERDCILCGICNGVVESIEDKEKRHNAREEIARFNTKIRNPFVSLFEKCNKYLLTPDMIRPEFKDPNAANDSADNVKSNNANPNKVDEISVNLNSNATWGDTY------NTAEKEA----------KENPAWISSNVANNF 823
            T +PA ++ +   + R FY       L+ LIR   + E+ ++E  +FD + +RS LN L+ DK V  +M+V T  +GK+   +Y+FIN++  +N   Y+L+   +++E  +R + +   + C  C  T++DL+   LF+       C  C   VE  E    + +AR  +ARFN +I  P   L  +     L+ D++ PE  +  A   S +    +      +    V     +++GD Y      N  E+E+          KE P W++ +    +
Sbjct:    8 TEVPASLKRLAKQVVRGFYGIEHALALDVLIRNPCVREEDMLELLKFDRKQLRSVLNTLKGDKFVKCRMRVETAPDGKTTRHNYYFINYRLLVNVVKYKLDHIRRRIETDERDSTNRASFRCPCCHNTFTDLEANQLFDPMTGTFRCTFCQTEVEEDESAVPKKDARTLVARFNEQI-EPIYVLLRETEDINLSHDLLEPEPTEIPALKQSRERAAPSGGAGAGMPGRDV-WKKGSSYGDLYTQNVVINMDEQESQGQAAEAKAPKERPVWLTESTVEPY 285

[Close]

BLAST of general transcription factor IIE 1 vs. Ensembl Sea Lamprey
Match: gtf2e1 (general transcription factor IIE, polypeptide 1, alpha [Source:ZFIN;Acc:ZDB-GENE-041210-221])

HSP 1 Score: 116.316 bits (290), Expect = 6.868e-30
Identity = 63/204 (30.88%), Postives = 109/204 (53.43%), Query Frame = 2

Query:   32 TNIPADIQDMILAIPRVFYDATEGAILNFLIRYNYLSEQQLVEKSEFDFQMVRSSLNKLRKDKLVDMKMQVSTDENGKSINTSYFFINFKQALNCFMYRLESSYKKLEEAQRQNISSGDYCCTECGQTYSDLDIMSLFNFERDCILCGICNGVVESIEDKEKRHNAREEIARFNTKIRNPFVSLFEKCNKYLLTPDMIRPEFKD 643
            T +PA ++ +   I R FY +     L+ LIR   + E+ + E  +FD + +RS LN L+ DK +  +M + T  +GKS   +Y+FIN++  +N   Y+L+   +KLE  +R + +   + C +C +T++DL+   L++      +C  C   VE  E    + +AR  +ARFN +I  P  +L  +     L+ D++ PE  D
Sbjct:    8 TEVPASLKRLAKFIVRGFYGSEYALALDVLIRNPCVREEDIQELLKFDRKQLRSVLNTLKADKFIKCRMCMETAPDGKSTRHNYYFINYRLLVNVVKYKLDHMRRKLETDERDSTNRASFRCPDCSKTFTDLEANQLYDLASGLFMCTFCRREVEEDESAVPKKDARTLVARFNEQI-EPIYALLRETEDINLSHDVLEPEPSD 210

[Close]

BLAST of general transcription factor IIE 1 vs. Ensembl Sea Lamprey
Match: gtf2e1 (general transcription factor IIE, polypeptide 1, alpha [Source:ZFIN;Acc:ZDB-GENE-041210-221])

HSP 1 Score: 116.316 bits (290), Expect = 7.000e-30
Identity = 63/204 (30.88%), Postives = 109/204 (53.43%), Query Frame = 2

Query:   32 TNIPADIQDMILAIPRVFYDATEGAILNFLIRYNYLSEQQLVEKSEFDFQMVRSSLNKLRKDKLVDMKMQVSTDENGKSINTSYFFINFKQALNCFMYRLESSYKKLEEAQRQNISSGDYCCTECGQTYSDLDIMSLFNFERDCILCGICNGVVESIEDKEKRHNAREEIARFNTKIRNPFVSLFEKCNKYLLTPDMIRPEFKD 643
            T +PA ++ +   I R FY +     L+ LIR   + E+ + E  +FD + +RS LN L+ DK +  +M + T  +GKS   +Y+FIN++  +N   Y+L+   +KLE  +R + +   + C +C +T++DL+   L++      +C  C   VE  E    + +AR  +ARFN +I  P  +L  +     L+ D++ PE  D
Sbjct:    8 TEVPASLKRLAKFIVRGFYGSEYALALDVLIRNPCVREEDIQELLKFDRKQLRSVLNTLKADKFIKCRMCMETAPDGKSTRHNYYFINYRLLVNVVKYKLDHMRRKLETDERDSTNRASFRCPDCSKTFTDLEANQLYDLASGLFMCTFCRREVEEDESAVPKKDARTLVARFNEQI-EPIYALLRETEDINLSHDVLEPEPSD 210

[Close]

BLAST of general transcription factor IIE 1 vs. Ensembl Sea Lamprey
Match: gtf2e1 (general transcription factor IIE, polypeptide 1, alpha [Source:ZFIN;Acc:ZDB-GENE-041210-221])

HSP 1 Score: 114.005 bits (284), Expect = 1.899e-29
Identity = 63/204 (30.88%), Postives = 109/204 (53.43%), Query Frame = 2

Query:   32 TNIPADIQDMILAIPRVFYDATEGAILNFLIRYNYLSEQQLVEKSEFDFQMVRSSLNKLRKDKLVDMKMQVSTDENGKSINTSYFFINFKQALNCFMYRLESSYKKLEEAQRQNISSGDYCCTECGQTYSDLDIMSLFNFERDCILCGICNGVVESIEDKEKRHNAREEIARFNTKIRNPFVSLFEKCNKYLLTPDMIRPEFKD 643
            T +PA ++ +   I R FY +     L+ LIR   + E+ + E  +FD + +RS LN L+ DK +  +M + T  +GKS   +Y+FIN++  +N   Y+L+   +KLE  +R + +   + C +C +T++DL+   L++      +C  C   VE  E    + +AR  +ARFN +I  P  +L  +     L+ D++ PE  D
Sbjct:    8 TEVPASLKRLAKFIVRGFYGSEYALALDVLIRNPCVREEDIQELLKFDRKQLRSVLNTLKADKFIKCRMCMETAPDGKSTRHNYYFINYRLLVNVVKYKLDHMRRKLETDERDSTNRASFRCPDCSKTFTDLEANQLYDLASGLFMCTFCRREVEEDESAVPKKDARTLVARFNEQI-EPIYALLRETEDINLSHDVLEPEPSD 210

[Close]

BLAST of general transcription factor IIE 1 vs. Ensembl Yeast
Match: TFA1 (TFIIE large subunit; involved in recruitment of RNA polymerase II to the promoter, activation of TFIIH, and promoter opening [Source:SGD;Acc:S000001511])

HSP 1 Score: 70.0922 bits (170), Expect = 1.461e-13
Identity = 36/183 (19.67%), Postives = 91/183 (49.73%), Query Frame = 2

Query:   50 IQDMILAIPRVFYDATEGAILNFLIRYNYLSEQQLVEKSEFDFQMVRSSLNKLRKDKLVDMKMQVSTDENGKSINTSYFFINFKQALNCFMYRLESSYKKLEEAQRQNISSGDYCCTECGQTYSDLDIMSLFNFERDCILCGICNGVVESIEDKEKRHNAREEIARFNTKIRNPFVSLFEKCN 598
            +++++  + R FY  +   +L+ ++ ++ L+E  L +    +   +   + +LR D+L+ +  Q     N KS+   Y+++ +  A++   +++    ++L++   +N     Y C  C   Y+ L+ + L NF+R   LC +C+  +   +  +K    ++++ R   +I+ P +   +K +
Sbjct:    9 VKNLLKFVVRGFYGGSFVLVLDAILFHSVLAEDDLKQLLSINKTELGPLIARLRSDRLISIHKQREYPPNSKSVERVYYYVKYPHAIDAIKWKVHQVVQRLKDDLDKNSEPNGYMCPICLTKYTQLEAVQLLNFDRTEFLCSLCDEPLVEDDSGKKNKEKQDKLNRLMDQIQ-PIIDSLKKID 190

[Close]

BLAST of general transcription factor IIE 1 vs. Ensembl Nematostella
Match: EDO37785 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SES2])

HSP 1 Score: 106.301 bits (264), Expect = 3.295e-25
Identity = 75/292 (25.68%), Postives = 141/292 (48.29%), Query Frame = 2

Query:   32 TNIPADIQDMILAIPRVFYDATEGAILNFLI--RYNYLSEQQLVEKSEFDFQMVRSSLNKLRKDKLVDMKMQV-STDENGKSINTSYFFINFKQALNCFMYRLESSYKKLEEAQRQNISSGDYCCTECGQTYSDLDIMSLFNFERDCILCGICNGVVES-IEDKEKRHNAREEIARFNTKIRNPFVSLFEKCNKYLLTPDMIRPEF------KDPNAANDSADNVKSNNANPNKVDEISVNLNSNATWG--DTYNTAEKEAKENPAWISSNVANNFISNINQSENNSDKNSS 871
            T IP  ++ +   + R FYD  + AI+N L   ++  + E  L++   FD + +R +L +L+ DKL+  ++      + G ++  +Y+FINFK  +N   Y+L+   KK+E  ++Q  +   + C+EC   YSDL++  L +     + C  C+G+VE    + ++ +N R  +A+FN +I  P   L        L   ++ PE       K  + ++ S    +S  A+ ++    + +L    + G  D    A K  KE P W+  +  ++    + Q+   S  ++S
Sbjct:   12 TEIPPVLKRLAKVVVRGFYDTEQVAIINVLTNAKHPCVKEDDLMDLVRFDKRQLRQALVRLKNDKLIKQRIHKEKAPDTGMTLTFNYYFINFKVFVNVVKYKLDHVRKKIESDEKQAKNRPSFVCSECHNKYSDLEVDRLIDMTTGLLKCTYCSGIVEEDTSEIQEGNNKRTSLAKFNEQIE-PIFKLLRDSENINLADAILEPEPDLTSINKHVSHSHISGHASRSGWAS-DRYGMEATDLGIKISMGAEDEAGAANKRVKEAPIWMKQSTVHSAPEAVAQAATPSAASTS 301

[Close]

BLAST of general transcription factor IIE 1 vs. Ensembl Medaka
Match: gtf2e1 (general transcription factor IIE subunit 1 [Source:NCBI gene;Acc:101173377])

HSP 1 Score: 110.538 bits (275), Expect = 2.736e-26
Identity = 76/299 (25.42%), Postives = 136/299 (45.48%), Query Frame = 2

Query:   32 TNIPADIQDMILAIPRVFYDATEGAILNFLIRYNYLSEQQLVEKSEFDFQMVRSSLNKLRKDKLVDMKMQVSTDENGKSINTSYFFINFKQALNCFMYRLESSYKKLEEAQRQNISSGDYCCTECGQTYSDLDIMSLFNFERDCILCGICNGVVESIEDKEKRHNAREEIARFNTKIRNPFVSLFEKCNKYLLTPDMIRPEFKDPNAANDSADNVKSNNANPNKVDEISVNLNSNATWGDTYNT----------AEKEA-------KENPAWISSNVANNFISNINQSENNSDKNSSAQ 877
            T +PA ++ +   + R FY+      L+ LIR   + E+ + E  +FD + +RS LN L+ DK V  +M+V T  +GK+   +Y+FIN++  +N   Y+L+   +++E  +R + +   + C  C   ++DL+   LF+       C  C   VE  ED     + R  +ARFN +I  P  +L  +     L+ D++ PE  +  A   S +   +  AN              A++ D Y            A+++A       KE P W++ +      S+ +  +++      AQ
Sbjct:    8 TEVPAALKRLAKQVVRGFYEVEHALALDVLIRNPCVREEDMQELLKFDRKQLRSVLNTLKADKFVKCRMRVETAPDGKTTRHNYYFINYRVLVNVVKYKLDHMRRRIETDERDSTNRASFRCPCCSSAFTDLEANLLFDMMTGTFRCTFCQTEVE--EDSSVCPDGRTLVARFNEQI-EPIYALLRETEDVNLSHDLLEPEPAEIPALKQSRERAAAAAANAAGGQHREAWSTKGASYSDLYTQNVVISMDEQDAQQKAIGEAKALKERPVWLTQSTVQGAYSDADALKSDGAALPGAQ 303

[Close]

BLAST of general transcription factor IIE 1 vs. Planmine SMEST
Match: SMESG000064941.1 (SMESG000064941.1)

HSP 1 Score: 824.313 bits (2128), Expect = 0.000e+0
Identity = 398/398 (100.00%), Postives = 398/398 (100.00%), Query Frame = 2

Query:   20 MEKRTNIPADIQDMILAIPRVFYDATEGAILNFLIRYNYLSEQQLVEKSEFDFQMVRSSLNKLRKDKLVDMKMQVSTDENGKSINTSYFFINFKQALNCFMYRLESSYKKLEEAQRQNISSGDYCCTECGQTYSDLDIMSLFNFERDCILCGICNGVVESIEDKEKRHNAREEIARFNTKIRNPFVSLFEKCNKYLLTPDMIRPEFKDPNAANDSADNVKSNNANPNKVDEISVNLNSNATWGDTYNTAEKEAKENPAWISSNVANNFISNINQSENNSDKNSSAQADNITLTMAPGRVPGAITTVNSSMPVADIMSVLLANEYCVENSIKFYENLRKDLHYKPLQSNLFKVLVNGASYDIWNVTEEMFERMTKEEIIQFKSLGRRLHDYCYDSMYIC 1213
            MEKRTNIPADIQDMILAIPRVFYDATEGAILNFLIRYNYLSEQQLVEKSEFDFQMVRSSLNKLRKDKLVDMKMQVSTDENGKSINTSYFFINFKQALNCFMYRLESSYKKLEEAQRQNISSGDYCCTECGQTYSDLDIMSLFNFERDCILCGICNGVVESIEDKEKRHNAREEIARFNTKIRNPFVSLFEKCNKYLLTPDMIRPEFKDPNAANDSADNVKSNNANPNKVDEISVNLNSNATWGDTYNTAEKEAKENPAWISSNVANNFISNINQSENNSDKNSSAQADNITLTMAPGRVPGAITTVNSSMPVADIMSVLLANEYCVENSIKFYENLRKDLHYKPLQSNLFKVLVNGASYDIWNVTEEMFERMTKEEIIQFKSLGRRLHDYCYDSMYIC
Sbjct:    1 MEKRTNIPADIQDMILAIPRVFYDATEGAILNFLIRYNYLSEQQLVEKSEFDFQMVRSSLNKLRKDKLVDMKMQVSTDENGKSINTSYFFINFKQALNCFMYRLESSYKKLEEAQRQNISSGDYCCTECGQTYSDLDIMSLFNFERDCILCGICNGVVESIEDKEKRHNAREEIARFNTKIRNPFVSLFEKCNKYLLTPDMIRPEFKDPNAANDSADNVKSNNANPNKVDEISVNLNSNATWGDTYNTAEKEAKENPAWISSNVANNFISNINQSENNSDKNSSAQADNITLTMAPGRVPGAITTVNSSMPVADIMSVLLANEYCVENSIKFYENLRKDLHYKPLQSNLFKVLVNGASYDIWNVTEEMFERMTKEEIIQFKSLGRRLHDYCYDSMYIC 398

The following BLAST results are available for this feature:

BLAST of general transcription factor IIE 1 vs. Ensembl Human
BLAST of general transcription factor IIE 1 vs. Ensembl Celegans
BLAST of general transcription factor IIE 1 vs. Ensembl Fly
BLAST of general transcription factor IIE 1 vs. Ensembl Zebrafish
BLAST of general transcription factor IIE 1 vs. Ensembl Xenopus
BLAST of general transcription factor IIE 1 vs. Ensembl Mouse
BLAST of general transcription factor IIE 1 vs. UniProt/SwissProt
BLAST of general transcription factor IIE 1 vs. TrEMBL
BLAST of general transcription factor IIE 1 vs. Ensembl Cavefish
BLAST of general transcription factor IIE 1 vs. Ensembl Sea Lamprey
BLAST of general transcription factor IIE 1 vs. Ensembl Yeast
BLAST of general transcription factor IIE 1 vs. Ensembl Nematostella
BLAST of general transcription factor IIE 1 vs. Ensembl Medaka
BLAST of general transcription factor IIE 1 vs. Planmine SMEST

BLAST of general transcription factor IIE 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 2


Match Name	E-value	Identity	Description
GTF2E1	6.033e-28	25.17	general transcription factor IIE subunit 1 [Source...	[more]
GTF2E1	1.636e-15	31.25	general transcription factor IIE subunit 1 [Source...	[more]

BLAST of general transcription factor IIE 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1


Match Name	E-value	Identity	Description
gtf-2E1	1.156e-20	25.00	General Transcription Factor homolog; TFIIE-alpha ...	[more]

BLAST of general transcription factor IIE 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1


Match Name	E-value	Identity	Description
TfIIEalpha	9.025e-27	25.27	gene:FBgn0015828 transcript:FBtr0076108	[more]

BLAST of general transcription factor IIE 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
gtf2e1	7.491e-27	30.35	general transcription factor IIE, polypeptide 1, a...	[more]
gtf2e1	7.491e-27	30.35	general transcription factor IIE, polypeptide 1, a...	[more]
gtf2e1	7.491e-27	30.35	general transcription factor IIE, polypeptide 1, a...	[more]
gtf2e1	7.491e-27	30.35	general transcription factor IIE, polypeptide 1, a...	[more]
gtf2e1	1.238e-12	34.41	general transcription factor IIE, polypeptide 1, a...	[more]

BLAST of general transcription factor IIE 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2


Match Name	E-value	Identity	Description
npbwr1	3.084e-26	30.39	neuropeptides B/W receptor 1 [Source:Xenbase;Acc:X...	[more]
mgc89226	9.148e-25	28.86	mgc89226 protein [Source:Xenbase;Acc:XB-GENE-58049...	[more]

BLAST of general transcription factor IIE 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1


Match Name	E-value	Identity	Description
Gtf2e1	4.163e-27	25.84	general transcription factor II E, polypeptide 1 (...	[more]

BLAST of general transcription factor IIE 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q5R8H5\|T2EA_PONAB	1.366e-27	25.50	General transcription factor IIE subunit 1 OS=Pong...	[more]
sp\|P29083\|T2EA_HUMAN	2.897e-27	25.17	General transcription factor IIE subunit 1 OS=Homo...	[more]
sp\|Q9D0D5\|T2EA_MOUSE	2.912e-26	25.84	General transcription factor IIE subunit 1 OS=Mus ...	[more]
sp\|A6QLI8\|T2EA_BOVIN	5.623e-26	25.50	General transcription factor IIE subunit 1 OS=Bos ...	[more]
sp\|Q9P3W1\|T2EA_SCHPO	7.073e-13	22.47	Transcription initiation factor IIE subunit alpha ...	[more]

BLAST of general transcription factor IIE 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A0F7CYH0	0.000e+0	99.30	General transcription factor IIE 1 (Fragment) OS=S...	[more]
A0A0R3VUT7	1.115e-40	27.50	HTH TFE/IIEalpha-type domain-containing protein OS...	[more]
A0A0R3WJ21	2.608e-38	27.83	HTH TFE/IIEalpha-type domain-containing protein OS...	[more]
A0A3Q0KU55	2.743e-38	26.03	Putative transcription initiation factor IIE, alph...	[more]
A0A430Q3S6	6.515e-38	26.57	Transcription initiation factor TFIIE subunit alph...	[more]

BLAST of general transcription factor IIE 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2


Match Name	E-value	Identity	Description
gtf2e1	6.767e-28	26.43	general transcription factor IIE subunit 1 [Source...	[more]
gtf2e1	6.767e-28	26.43	general transcription factor IIE subunit 1 [Source...	[more]

BLAST of general transcription factor IIE 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3


Match Name	E-value	Identity	Description
gtf2e1	6.868e-30	30.88	general transcription factor IIE, polypeptide 1, a...	[more]
gtf2e1	7.000e-30	30.88	general transcription factor IIE, polypeptide 1, a...	[more]
gtf2e1	1.899e-29	30.88	general transcription factor IIE, polypeptide 1, a...	[more]

BLAST of general transcription factor IIE 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
TFA1	1.461e-13	19.67	TFIIE large subunit; involved in recruitment of RN...	[more]

BLAST of general transcription factor IIE 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO37785	3.295e-25	25.68	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of general transcription factor IIE 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1


Match Name	E-value	Identity	Description
gtf2e1	2.736e-26	25.42	general transcription factor IIE subunit 1 [Source...	[more]

BLAST of general transcription factor IIE 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1


Match Name	E-value	Identity	Description
SMESG000064941.1	0.000e+0	100.00	SMESG000064941.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Cross References

External references for this transcript


Database	Accession
SmedGD GBrowse	SMED30021388
GenBank	AKG62104.1

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30021388 ID=SMED30021388|Name=general transcription factor IIE 1|organism=Schmidtea mediterranea sexual|type=transcript|length=1263bp
CTATATAAATCTTATATGAATGGAAAAACGTACAAATATACCTGCAGATA
TTCAAGATATGATTTTAGCAATTCCTCGTGTCTTTTACGATGCAACAGAA
GGAGCAATTCTTAACTTTTTAATTCGCTATAATTATCTCAGTGAACAACA
ATTAGTTGAGAAATCTGAGTTTGATTTTCAAATGGTTCGGTCTTCGTTAA
ATAAATTAAGAAAAGATAAATTAGTTGATATGAAAATGCAAGTTTCCACT
GATGAAAATGGCAAATCAATCAATACATCTTATTTTTTCATTAATTTTAA
ACAAGCCTTGAACTGCTTTATGTACAGACTAGAAAGTAGTTATAAGAAAC
TCGAAGAAGCTCAAAGACAAAATATAAGCAGCGGTGATTACTGCTGTACT
GAATGTGGTCAAACATACAGCGATTTAGATATAATGTCATTGTTTAATTT
TGAAAGAGACTGTATTCTCTGTGGTATCTGTAACGGAGTCGTTGAATCAA
TTGAAGACAAAGAAAAGCGACATAATGCCCGTGAAGAAATAGCCAGATTT
AACACAAAAATAAGGAATCCGTTTGTATCGCTGTTTGAAAAATGCAACAA
ATATTTATTGACTCCCGATATGATTCGCCCAGAATTTAAGGATCCAAATG
CTGCCAACGATTCTGCTGATAATGTGAAATCTAACAACGCAAACCCGAAC
AAAGTGGATGAAATCTCAGTCAACCTCAACTCCAACGCCACCTGGGGCGA
TACATATAATACGGCAGAAAAAGAAGCCAAAGAAAATCCCGCATGGATCA
GTTCGAACGTGGCGAATAATTTCATTTCCAATATTAACCAATCAGAAAAC
AATTCAGATAAAAACTCATCTGCTCAAGCTGACAACATCACATTGACCAT
GGCTCCCGGCAGGGTCCCCGGTGCCATAACGACGGTTAATTCCTCGATGC
CTGTCGCTGACATCATGAGCGTTCTTTTAGCCAATGAATATTGCGTTGAG
AATTCGATAAAGTTCTATGAGAATCTAAGAAAAGATCTCCACTATAAACC
TCTGCAATCCAATTTATTCAAAGTGCTTGTCAATGGTGCCAGTTATGACA
TCTGGAATGTAACTGAGGAGATGTTTGAGCGCATGACCAAAGAAGAAATC
ATTCAGTTTAAATCGCTAGGACGACGGCTTCATGATTATTGCTATGATTC
GATGTATATCTGTTAATAAATTGTGGCAATTTGTTTTTTACTAGTTTACA
CTCATCTTTTAAA

protein sequence of SMED30021388-orf-1

>SMED30021388-orf-1 ID=SMED30021388-orf-1|Name=SMED30021388-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=399bp
MEKRTNIPADIQDMILAIPRVFYDATEGAILNFLIRYNYLSEQQLVEKSE
FDFQMVRSSLNKLRKDKLVDMKMQVSTDENGKSINTSYFFINFKQALNCF
MYRLESSYKKLEEAQRQNISSGDYCCTECGQTYSDLDIMSLFNFERDCIL
CGICNGVVESIEDKEKRHNAREEIARFNTKIRNPFVSLFEKCNKYLLTPD
MIRPEFKDPNAANDSADNVKSNNANPNKVDEISVNLNSNATWGDTYNTAE
KEAKENPAWISSNVANNFISNINQSENNSDKNSSAQADNITLTMAPGRVP
GAITTVNSSMPVADIMSVLLANEYCVENSIKFYENLRKDLHYKPLQSNLF
KVLVNGASYDIWNVTEEMFERMTKEEIIQFKSLGRRLHDYCYDSMYIC*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **biological process**
Term	Definition
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006367	transcription initiation from RNA polymerase II promoter

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000429	neoblast
PLANA:0002109	X1 cell
PLANA:0002111	X2 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR039997	TFE
IPR002853	TFIIE_asu
IPR024550	TFIIEa/SarR/Rpc3_HTH_dom
IPR013083	Znf_RING/FYVE/PHD

Vocabulary: **molecular function**
Term	Definition
GO:0043565	sequence-specific DNA binding

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR002853	Transcription initiation factor IIE subunit alpha, N-terminal	SMART	SM00531	tfiie3	coord: 25..172 e-value: 6.1E-17 score: 72.3
IPR013083	Zinc finger, RING/FYVE/PHD-type	GENE3D	G3DSA:3.30.40.10		coord: 110..171 e-value: 5.9E-10 score: 40.4
IPR024550	TFIIEalpha/SarR/Rpc3 HTH domain	PFAM	PF02002	TFIIE_alpha	coord: 20..118 e-value: 3.6E-13 score: 49.3
IPR039997	Transcription factor E	PANTHER	PTHR13097	TRANSCRIPTION INITIATION FACTOR IIE, ALPHA SUBUNIT	coord: 11..288
None	No IPR available	SUPERFAMILY	SSF57783	Zinc beta-ribbon	coord: 110..160