Methyltransf_11 domain-containing protein

Overview
NameMethyltransf_11 domain-containing protein
Smed IDSMED30021372
Length (bp)928
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Methyltransf_11 domain-containing protein (SMED30021372) t-SNE clustered cells

Violin plots show distribution of expression levels for Methyltransf_11 domain-containing protein (SMED30021372) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Methyltransf_11 domain-containing protein (SMED30021372) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Methyltransf_11 domain-containing protein (SMED30021372) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30021372

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
posterior sideSMED30021372h1SMcG0011858 dd_Smed_v4_10513_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
posterior muscle cellSMED30021372h1SMcG0011858 dd_Smed_v4_10513_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Human
Match: EEF1AKMT4 (EEF1A lysine methyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:53611])

HSP 1 Score: 127.102 bits (318), Expect = 2.431e-34
Identity = 63/199 (31.66%), Postives = 106/199 (53.27%), Query Frame = 1 
Query:  163 YWDKRYENEDN---YEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCKYKDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANE-NQWTYAAKFRIQFENFMLNVHNILKRDGKFLSVSFHQPMFRLPLLIDFSNHSTPF--WKIKIEEIESGFHFILYNFEKSQAL 741
            YWD+RY+   +   Y+W         +L+       ++L+LGCGNS LSYEL+  G+ N+ S DYS  ++  M+ ++  + +L+WE  D+  L +   SFD++ EKG +DA+LA E + WT +++     +  +  V  +L   G+F+S++   P FR        +++  +  W ++     SGFHF LY   K   L
Sbjct:   25 YWDQRYQGAADSAPYDWFGDFSSFRALLEPELRPEDRILVLGCGNSALSYELFLGGFPNVTSVDYSSVVVAAMQARHAHVPQLRWETMDVRKLDFPSASFDVVLEKGTLDALLAGERDPWTVSSEGVHTVDQVLSEVSRVLVPGGRFISMTSAAPHFRT------RHYAQAYYGWSLRHATYGSGFHFHLYLMHKGGKL 217
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Human
Match: ECE2 (endothelin converting enzyme 2 [Source:HGNC Symbol;Acc:HGNC:13275])

HSP 1 Score: 103.99 bits (258), Expect = 5.210e-24
Identity = 45/125 (36.00%), Postives = 75/125 (60.00%), Query Frame = 1 
Query:  163 YWDKRYENEDN---YEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCKYKDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANE-NQWTYAAK 525
            YWD+RY+   +   Y+W         +L+       ++L+LGCGNS LSYEL+  G+ N+ S DYS  ++  M+ ++  + +L+WE  D+  L +   SFD++ EKG +DA+LA E + WT +++
Sbjct:   25 YWDQRYQGAADSAPYDWFGDFSSFRALLEPELRPEDRILVLGCGNSALSYELFLGGFPNVTSVDYSSVVVAAMQARHAHVPQLRWETMDVRKLDFPSASFDVVLEKGTLDALLAGERDPWTVSSE 149
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Human
Match: EEF1AKNMT (eEF1A lysine and N-terminal methyltransferase [Source:HGNC Symbol;Acc:HGNC:24248])

HSP 1 Score: 97.0561 bits (240), Expect = 9.234e-22
Identity = 53/184 (28.80%), Postives = 95/184 (51.63%), Query Frame = 1 
Query:  148 FSTKSYWDKRYENEDN--YEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMK-CKYKDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANENQWTYAAKFRIQFENFMLNVHNILKRDGKFLSVSFHQPMFRLPLLIDFSNHSTPFWKIKIEEI 690
            F +  YW+K ++      +EW     ++  +L +Y     KVL++GCGNS LS +LY  GYR+I++ D SE +I++MK C      ++ +   DM  + +   SF ++ +KG +DAVL +E + T       Q +  +  V  +L+  G++L +S  Q       +  FS      W +++ ++
Sbjct:   11 FGSVDYWEKFFQQRGKKAFEWYGTYLELCGVLHKYIKPREKVLVIGCGNSELSEQLYDVGYRDIVNIDISEVVIKQMKECNATRRPQMSFLKMDMTQMEFPDASFQVVLDKGTLDAVLTDEEEKTLQ-----QVDRMLAEVGRVLQVGGRYLCISLAQAHILKKAVGHFSREG---WMVRVHQV 186
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Human
Match: EEF1AKNMT (eEF1A lysine and N-terminal methyltransferase [Source:HGNC Symbol;Acc:HGNC:24248])

HSP 1 Score: 86.6557 bits (213), Expect = 2.834e-18
Identity = 46/146 (31.51%), Postives = 79/146 (54.11%), Query Frame = 1 
Query:  148 FSTKSYWDKRYENEDN--YEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMK-CKYKDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANENQWTYAAKFRIQFENFMLNVHNILK 576
            F +  YW+K ++      +EW     ++  +L +Y     KVL++GCGNS LS +LY  GYR+I++ D SE +I++MK C      ++ +   DM  + +   SF ++ +KG +DAVL +E + T       Q +  +  V  +L+
Sbjct:   11 FGSVDYWEKFFQQRGKKAFEWYGTYLELCGVLHKYIKPREKVLVIGCGNSELSEQLYDVGYRDIVNIDISEVVIKQMKECNATRRPQMSFLKMDMTQMEFPDASFQVVLDKGTLDAVLTDEEEKTLQ-----QVDRMLAEVGRVLQ 151
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Celegans
Match: C17E4.11 (pep chromosome:WBcel235:I:9419973:9420813:-1 gene:WBGene00044236.1 transcript:C17E4.11.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C17E4.11)

HSP 1 Score: 125.176 bits (313), Expect = 1.673e-34
Identity = 68/213 (31.92%), Postives = 120/213 (56.34%), Query Frame = 1 
Query:  148 FSTKSYWDKRYENEDNYEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCKYKDIMELKWECHDMFDLP-YDWNSFDIIFEKGVIDAVLANE-NQWTYAAKFRIQFENFMLNVHNILKRDGKFLSVSFHQPMFRLPLLIDFSNHSTPFWKIKIEEIESGFHFILYNFEKSQALHHSVNDLISKYSK 780
            ++   YWD+R++ E N+EWL  ++    I+    + ++++  +GCG+S +S +L+  GYRNI + DYS+ +IE  + +Y +   ++W   D+  L   + +SFD++FEK  I+A+L  E + W  +       EN   ++  +LK +G F+SVSF QP FR+P L+   N     W +++ E    FH+ +Y   K  +L+  + D  S  +K
Sbjct:    7 YARMDYWDERFQTEKNFEWLSGLNAFQHIITPLFSKDSRIAHIGCGSSQVSMQLWELGYRNITNIDYSQVLIENGRLEYPN---MEWISDDITTLINCESSSFDVVFEKATIEAILVTEKSAWEPSDSALHNLENIFSSICRVLKPNGIFISVSFTQPHFRIPALLREKN-----WSVEMFEFGDTFHYYVYVCRKGNSLNKELADRYSSIAK 211
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Celegans
Match: C01B10.8 (pep chromosome:WBcel235:IV:6635039:6638155:1 gene:WBGene00015282.1 transcript:C01B10.8.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C01B10.8)

HSP 1 Score: 72.7886 bits (177), Expect = 4.662e-14
Identity = 51/200 (25.50%), Postives = 96/200 (48.00%), Query Frame = 1 
Query:  145 NFSTKSYWDKRY-ENEDNYEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCKYKDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANENQWTYAAKFRIQFENFMLNVHNILKRDGKFLSVSFHQPMFRLPLLIDF-SNHSTPF--WKIKIEEIE---SGFHFILYNF 723
            +F+  +YW   + + +  +EW    + ++ ++ +Y       L LGCGNS L+ +LY  G+  I S D   ++I     K K+ + + +E  D  +L     +  I+ +KG +DA+L      +  A     FE     VH +L   G+++ V+  QP      + +F  NH  P   + ++++++E   SGF   ++ F
Sbjct:    9 SFTDPAYWKNFFAKRKSPFEWYGDYNSLSNVIDKYLKPKDTFLQLGCGNSELATQLYDNGFHCIHSIDVEPSVIATQIRKNKERLGMTFETGDAANLSMADEAHTIVIDKGTLDALLPPSASESDEALVTKMFE----EVHRVLASGGRYIIVTLAQPH-----ITEFWINHFYPLKQYILRVQKVENKASGFPMPVFCF 199
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Celegans
Match: C01B10.8 (pep chromosome:WBcel235:IV:6635089:6638155:1 gene:WBGene00015282.1 transcript:C01B10.8.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C01B10.8)

HSP 1 Score: 72.7886 bits (177), Expect = 4.662e-14
Identity = 51/200 (25.50%), Postives = 96/200 (48.00%), Query Frame = 1 
Query:  145 NFSTKSYWDKRY-ENEDNYEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCKYKDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANENQWTYAAKFRIQFENFMLNVHNILKRDGKFLSVSFHQPMFRLPLLIDF-SNHSTPF--WKIKIEEIE---SGFHFILYNF 723
            +F+  +YW   + + +  +EW    + ++ ++ +Y       L LGCGNS L+ +LY  G+  I S D   ++I     K K+ + + +E  D  +L     +  I+ +KG +DA+L      +  A     FE     VH +L   G+++ V+  QP      + +F  NH  P   + ++++++E   SGF   ++ F
Sbjct:    9 SFTDPAYWKNFFAKRKSPFEWYGDYNSLSNVIDKYLKPKDTFLQLGCGNSELATQLYDNGFHCIHSIDVEPSVIATQIRKNKERLGMTFETGDAANLSMADEAHTIVIDKGTLDALLPPSASESDEALVTKMFE----EVHRVLASGGRYIIVTLAQPH-----ITEFWINHFYPLKQYILRVQKVENKASGFPMPVFCF 199
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Celegans
Match: F29B9.1 (Protein-lysine N-methyltransferase CELE_F29B9.1 [Source:UniProtKB/TrEMBL;Acc:Q9GYH9])

HSP 1 Score: 55.8398 bits (133), Expect = 5.393e-9
Identity = 44/174 (25.29%), Postives = 82/174 (47.13%), Query Frame = 1 
Query:  145 NFSTKSYWDKRYENE--------DNYEWLIKIDQVNEILK----RYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCKYK---------DIMELKWECHDMFDLPYDWNS--FDIIFEKGVIDAV-LANENQWTYAAKFRIQFENFMLNVHNILKRDGKFL 594
               TK +WD+RYE E        D  E          I+K         +AK+L LGCGN ++  +L +KG++++   DY +  ++      K         +++++++E  D+   P D+ S  FD+I +KG  DA+ L++E +         + + ++  + N L   G+F+
Sbjct:   15 QLGTKDFWDQRYELELKNFKQHGDEGEVWFGTSSETRIVKYLIDSKTGKDAKILDLGCGNGSVLRKLRSKGFQSLKGVDYCQKAVDLSAAASKAEREEEEDEELVDIEFEQLDITTPPADFFSSKFDVILDKGTWDAMSLSDERE--------ARLKAYLGFLDNGLSAGGRFV 180
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Celegans
Match: F29B9.1 (Protein-lysine N-methyltransferase CELE_F29B9.1 [Source:UniProtKB/TrEMBL;Acc:Q9GYH9])

HSP 1 Score: 55.8398 bits (133), Expect = 5.393e-9
Identity = 44/174 (25.29%), Postives = 82/174 (47.13%), Query Frame = 1 
Query:  145 NFSTKSYWDKRYENE--------DNYEWLIKIDQVNEILK----RYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCKYK---------DIMELKWECHDMFDLPYDWNS--FDIIFEKGVIDAV-LANENQWTYAAKFRIQFENFMLNVHNILKRDGKFL 594
               TK +WD+RYE E        D  E          I+K         +AK+L LGCGN ++  +L +KG++++   DY +  ++      K         +++++++E  D+   P D+ S  FD+I +KG  DA+ L++E +         + + ++  + N L   G+F+
Sbjct:   15 QLGTKDFWDQRYELELKNFKQHGDEGEVWFGTSSETRIVKYLIDSKTGKDAKILDLGCGNGSVLRKLRSKGFQSLKGVDYCQKAVDLSAAASKAEREEEEDEELVDIEFEQLDITTPPADFFSSKFDVILDKGTWDAMSLSDERE--------ARLKAYLGFLDNGLSAGGRFV 180
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Fly
Match: CG2614 (gene:FBgn0032873 transcript:FBtr0339520)

HSP 1 Score: 75.485 bits (184), Expect = 8.175e-15
Identity = 46/169 (27.22%), Postives = 87/169 (51.48%), Query Frame = 1 
Query:  148 FSTKSYWDK--RYENEDNYEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKM-KCKYKDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANENQWTYAAKFRIQFENFMLNVHNILKRDGKFLSVSFHQPMFRLPLLIDF 645
            F+   YW++  +   E  +EW  +  ++ + + +Y     ++L+LGCGNS LS ++Y  G+R+I + D S   ++KM +   K   E+K+   D   + +   SF +  +KG +DA+ A++   T A       EN+   +   ++  G+++ +S  Q    L  L+DF
Sbjct:   11 FAQTDYWNEFFKKRGEKAFEWYGEYLELCDQIHKYIKPADRILMLGCGNSKLSMDMYDTGFRDITNIDISPIAVKKMLELNAKSRPEMKFLQMDATAMTFPDESFSVSLDKGTLDALFADDEPETRAV-----VENYFKEILRTMRNGGRYVGISLLQEHI-LNFLLDF 173
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Fly
Match: CG2614 (gene:FBgn0032873 transcript:FBtr0081388)

HSP 1 Score: 75.485 bits (184), Expect = 8.824e-15
Identity = 46/169 (27.22%), Postives = 87/169 (51.48%), Query Frame = 1 
Query:  148 FSTKSYWDK--RYENEDNYEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKM-KCKYKDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANENQWTYAAKFRIQFENFMLNVHNILKRDGKFLSVSFHQPMFRLPLLIDF 645
            F+   YW++  +   E  +EW  +  ++ + + +Y     ++L+LGCGNS LS ++Y  G+R+I + D S   ++KM +   K   E+K+   D   + +   SF +  +KG +DA+ A++   T A       EN+   +   ++  G+++ +S  Q    L  L+DF
Sbjct:   11 FAQTDYWNEFFKKRGEKAFEWYGEYLELCDQIHKYIKPADRILMLGCGNSKLSMDMYDTGFRDITNIDISPIAVKKMLELNAKSRPEMKFLQMDATAMTFPDESFSVSLDKGTLDALFADDEPETRAV-----VENYFKEILRTMRNGGRYVGISLLQEHI-LNFLLDF 173
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Zebrafish
Match: ece2a (endothelin converting enzyme 2a [Source:ZFIN;Acc:ZDB-GENE-070912-214])

HSP 1 Score: 133.65 bits (335), Expect = 3.996e-37
Identity = 68/194 (35.05%), Postives = 102/194 (52.58%), Query Frame = 1 
Query:  163 YWDKRYENEDNYEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCKYKDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANE-NQWTYAAKFRIQFENFMLNVHNILKRDGKFLSVSFHQPMFRLPLLIDFSNHSTPFWKIKIEEIESGFHFILYNFEKSQAL 741
            YW++RY  E+++EW     +   +LK++      +L+LGCGNS LSY++   GY +I + DYS   +E M  ++KD  +L W C D   L +    FD++ EKG +DA+L  E + W  +          +L V  +LK  G+F+SV+F QP FR  L       +   W IK     S FH+ LY   K + L
Sbjct:   16 YWNERYRTEESFEWFGDFTKFGHLLKQHVGTEENILMLGCGNSALSYDMCQAGYSSITNVDYSSVCVESMAERHKDCAQLSWLCLDARRLAFPDGVFDVVLEKGTLDAMLVEETDPWKISENAARLLHQVLLEVSRVLKPGGRFISVTFAQPHFRKRLYA----QAEYDWSIKHYHYGSNFHYFLYVLTKGEKL 205
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Zebrafish
Match: ece2a (endothelin converting enzyme 2a [Source:ZFIN;Acc:ZDB-GENE-070912-214])

HSP 1 Score: 133.65 bits (335), Expect = 1.286e-36
Identity = 68/194 (35.05%), Postives = 102/194 (52.58%), Query Frame = 1 
Query:  163 YWDKRYENEDNYEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCKYKDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANE-NQWTYAAKFRIQFENFMLNVHNILKRDGKFLSVSFHQPMFRLPLLIDFSNHSTPFWKIKIEEIESGFHFILYNFEKSQAL 741
            YW++RY  E+++EW     +   +LK++      +L+LGCGNS LSY++   GY +I + DYS   +E M  ++KD  +L W C D   L +    FD++ EKG +DA+L  E + W  +          +L V  +LK  G+F+SV+F QP FR  L       +   W IK     S FH+ LY   K + L
Sbjct:   65 YWNERYRTEESFEWFGDFTKFGHLLKQHVGTEENILMLGCGNSALSYDMCQAGYSSITNVDYSSVCVESMAERHKDCAQLSWLCLDARRLAFPDGVFDVVLEKGTLDAMLVEETDPWKISENAARLLHQVLLEVSRVLKPGGRFISVTFAQPHFRKRLYA----QAEYDWSIKHYHYGSNFHYFLYVLTKGEKL 254
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Zebrafish
Match: ece2a (endothelin converting enzyme 2a [Source:ZFIN;Acc:ZDB-GENE-070912-214])

HSP 1 Score: 101.679 bits (252), Expect = 8.204e-26
Identity = 43/114 (37.72%), Postives = 67/114 (58.77%), Query Frame = 1 
Query:  163 YWDKRYENEDNYEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCKYKDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANEN 504
            YW++RY  E+++EW     +   +LK++      +L+LGCGNS LSY++   GY +I + DYS   +E M  ++KD  +L W C D   L +    FD++ EKG +DA+L  E 
Sbjct:   16 YWNERYRTEESFEWFGDFTKFGHLLKQHVGTEENILMLGCGNSALSYDMCQAGYSSITNVDYSSVCVESMAERHKDCAQLSWLCLDARRLAFPDGVFDVVLEKGTLDAMLVEET 129
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Zebrafish
Match: mettl13 (methyltransferase like 13 [Source:NCBI gene;Acc:557908])

HSP 1 Score: 82.0333 bits (201), Expect = 1.883e-17
Identity = 45/158 (28.48%), Postives = 80/158 (50.63%), Query Frame = 1 
Query:  148 FSTKSYWDK--RYENEDNYEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCKYKDIM-ELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANENQWTYAAKFRIQFENFMLNVHNILKRDGKFLSVSFHQ 612
            FS+  YW++  R   E  +EW    + +  +L +Y     KVL++GCGNS LS +LY  GYR + + D SET++  M  +  +   +L ++  D     ++  SF +  +KG +DA +A+E     A +        +  V  +L   G+++ ++  Q
Sbjct:   11 FSSADYWERFFRKRGEKAFEWYGDYNSLCGVLHKYIKPRDKVLVVGCGNSELSEQLYDVGYRQLTNIDISETVVSHMNQRNAERRPDLSFQQLDATQTGFESGSFQVTLDKGTLDA-MASEEDGALAGR-------MLAEVGRVLAVGGRYVCITLAQ 160
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Zebrafish
Match: mettl13 (methyltransferase like 13 [Source:NCBI gene;Acc:557908])

HSP 1 Score: 81.6481 bits (200), Expect = 8.583e-17
Identity = 45/158 (28.48%), Postives = 80/158 (50.63%), Query Frame = 1 
Query:  148 FSTKSYWDK--RYENEDNYEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCKYKDIM-ELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANENQWTYAAKFRIQFENFMLNVHNILKRDGKFLSVSFHQ 612
            FS+  YW++  R   E  +EW    + +  +L +Y     KVL++GCGNS LS +LY  GYR + + D SET++  M  +  +   +L ++  D     ++  SF +  +KG +DA +A+E     A +        +  V  +L   G+++ ++  Q
Sbjct:   11 FSSADYWERFFRKRGEKAFEWYGDYNSLCGVLHKYIKPRDKVLVVGCGNSELSEQLYDVGYRQLTNIDISETVVSHMNQRNAERRPDLSFQQLDATQTGFESGSFQVTLDKGTLDA-MASEEDGALAGR-------MLAEVGRVLAVGGRYVCITLAQ 160
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Xenopus
Match: bsk146 (brain specific kinase 146 [Source:Xenbase;Acc:XB-GENE-5880592])

HSP 1 Score: 111.309 bits (277), Expect = 7.338e-28
Identity = 70/238 (29.41%), Postives = 112/238 (47.06%), Query Frame = 1 
Query:  148 FSTKSYWDKRYENE----DNYEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCKYKDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANE-NQWTYAAKFRIQFENFMLNVHNILKRDGKFLSVSFHQPMFRLPLLIDFSNHSTP--FWKIKIEEIESGFHFILYNFEKSQALHHSVNDLISKYSKYQRTINRT-ISKESYNDNED 837
            +   SYWD RY  E    + Y+W  +  +  E+  R     A+ L+LGCG S+LS +LY +G   ++S DYS   I++M  K+     + W   D   L +   SFD + EKG +DA++  E + W   ++     +  +  V  +L  +G F+SV+F  P FR        +++ P   W +      S FH+ LY   K + L  +  DL    S +   I+   +   S  D+ED
Sbjct:   89 YKESSYWDARYREERALPNGYDWFGRYREFRELFIRELQPGARGLVLGCGTSSLSMDLYEEGICPLVSIDYSPICIKEMAEKHAGRHGMSWLVMDARKLQFAEGSFDFVIEKGTLDAMMVGERDPWRVTSEAIALIDEVLSEVSRVLSPNGCFISVTFSPPHFRT------RHYAQPSYSWSVSCNTYGSDFHYFLYTMRKGEKL--TAQDLERGQSLHNPYISPVHLPTLSEKDDED 318
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Xenopus
Match: eef1aknmt (methyltransferase like 13 [Source:NCBI gene;Acc:733963])

HSP 1 Score: 82.0333 bits (201), Expect = 1.053e-16
Identity = 50/187 (26.74%), Postives = 89/187 (47.59%), Query Frame = 1 
Query:  148 FSTKSYWDK--RYENEDNYEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCKYKDIME-LKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANENQWTYAAKFRIQFENFMLNVHNILKRDGKFLSVSFHQPMFRLPLLIDFSNHSTPFWKIKIEEIESG 699
            F+   YW++  R   E  +EW     ++  +L +Y     KVL++GCGNS LS  LY  G +N+ + D SE +I +MK +       + ++  D     +D + F  + +KG +DA++ + ++ T         +  M  +  +L   G+FL VS  Q      L+  FS      + I++ ++  G
Sbjct:   11 FAAPEYWEQFFRRRGERAFEWYGGYLELCGLLHKYIKPRDKVLVVGCGNSELSERLYDAGCQNLTNIDVSEVVIRQMKERNSSRRPNMTFQVMDATQTTFDDSYFQTVLDKGTLDAIMTDTDERTLETA-----DKMMSEIGRLLTCGGRFLCVSLAQAHVLEKLVGHFSQGG---FMIRVHQVMQG 189
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Xenopus
Match: eef1aknmt (methyltransferase like 13 [Source:NCBI gene;Acc:733963])

HSP 1 Score: 81.6481 bits (200), Expect = 1.192e-16
Identity = 50/187 (26.74%), Postives = 89/187 (47.59%), Query Frame = 1 
Query:  148 FSTKSYWDK--RYENEDNYEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCKYKDIME-LKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANENQWTYAAKFRIQFENFMLNVHNILKRDGKFLSVSFHQPMFRLPLLIDFSNHSTPFWKIKIEEIESG 699
            F+   YW++  R   E  +EW     ++  +L +Y     KVL++GCGNS LS  LY  G +N+ + D SE +I +MK +       + ++  D     +D + F  + +KG +DA++ + ++ T         +  M  +  +L   G+FL VS  Q      L+  FS      + I++ ++  G
Sbjct:   11 FAAPEYWEQFFRRRGERAFEWYGGYLELCGLLHKYIKPRDKVLVVGCGNSELSERLYDAGCQNLTNIDVSEVVIRQMKERNSSRRPNMTFQVMDATQTTFDDSYFQTVLDKGTLDAIMTDTDERTLETA-----DKMMSEIGRLLTCGGRFLCVSLAQAHVLEKLVGHFSQGG---FMIRVHQVMQG 189
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Mouse
Match: Eef1akmt4 (EEF1A lysine methyltransferase 4 [Source:MGI Symbol;Acc:MGI:5903914])

HSP 1 Score: 128.257 bits (321), Expect = 6.259e-35
Identity = 69/204 (33.82%), Postives = 108/204 (52.94%), Query Frame = 1 
Query:  163 YWDKRYENEDN---YEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCKYKDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANE-NQWTYAAKFRIQFENFMLNVHNILKRDGKFLSVSFHQPMFRLPLLIDFSNHSTPFWKIKIEEIESGFHFILYNFEKSQALHHSVNDL 762
            YWD+RY++  +   YEW         +L+       ++L+LGCGNS LSYEL+  G+ N+ S DYS  ++  M+ +Y  +  L+WE  D+  L +   SFD++ EKG +DA+LA E + W  +++     +  +  V  +L   G+F+S++   P FR    I     S   W ++     SGFHF  Y   K +AL  SV+ L
Sbjct:   25 YWDQRYKDAADSGPYEWFGDFASFRALLEPELCPEDRILVLGCGNSALSYELFLGGFPNVTSVDYSPVVVAAMQVRYAHVPSLRWETMDVRALDFPSGSFDVVLEKGTLDAMLAGEPDPWNVSSEGVHTVDQVLSEVSRLLVPGGRFISMTSAGPHFR----IRHYAQSRYDWSLRHTTYSSGFHFHFYIMHKGRAL--SVSQL 222
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Mouse
Match: Eef1akmt4 (EEF1A lysine methyltransferase 4 [Source:MGI Symbol;Acc:MGI:5903914])

HSP 1 Score: 103.219 bits (256), Expect = 4.219e-26
Identity = 45/116 (38.79%), Postives = 69/116 (59.48%), Query Frame = 1 
Query:  163 YWDKRYENEDN---YEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCKYKDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANE 501
            YWD+RY++  +   YEW         +L+       ++L+LGCGNS LSYEL+  G+ N+ S DYS  ++  M+ +Y  +  L+WE  D+  L +   SFD++ EKG +DA+LA E
Sbjct:   25 YWDQRYKDAADSGPYEWFGDFASFRALLEPELCPEDRILVLGCGNSALSYELFLGGFPNVTSVDYSPVVVAAMQVRYAHVPSLRWETMDVRALDFPSGSFDVVLEKGTLDAMLAGE 140
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Mouse
Match: Gm49333 (predicted gene, 49333 [Source:MGI Symbol;Acc:MGI:6121518])

HSP 1 Score: 103.219 bits (256), Expect = 6.179e-24
Identity = 45/116 (38.79%), Postives = 69/116 (59.48%), Query Frame = 1 
Query:  163 YWDKRYENEDN---YEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCKYKDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANE 501
            YWD+RY++  +   YEW         +L+       ++L+LGCGNS LSYEL+  G+ N+ S DYS  ++  M+ +Y  +  L+WE  D+  L +   SFD++ EKG +DA+LA E
Sbjct:   25 YWDQRYKDAADSGPYEWFGDFASFRALLEPELCPEDRILVLGCGNSALSYELFLGGFPNVTSVDYSPVVVAAMQVRYAHVPSLRWETMDVRALDFPSGSFDVVLEKGTLDAMLAGE 140
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Mouse
Match: Gm49333 (predicted gene, 49333 [Source:MGI Symbol;Acc:MGI:6121518])

HSP 1 Score: 102.834 bits (255), Expect = 6.973e-24
Identity = 45/116 (38.79%), Postives = 69/116 (59.48%), Query Frame = 1 
Query:  163 YWDKRYENEDN---YEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCKYKDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANE 501
            YWD+RY++  +   YEW         +L+       ++L+LGCGNS LSYEL+  G+ N+ S DYS  ++  M+ +Y  +  L+WE  D+  L +   SFD++ EKG +DA+LA E
Sbjct:   25 YWDQRYKDAADSGPYEWFGDFASFRALLEPELCPEDRILVLGCGNSALSYELFLGGFPNVTSVDYSPVVVAAMQVRYAHVPSLRWETMDVRALDFPSGSFDVVLEKGTLDAMLAGE 140
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Mouse
Match: Eef1aknmt (EEF1A lysine and N-terminal methyltransferase [Source:MGI Symbol;Acc:MGI:1918699])

HSP 1 Score: 93.2041 bits (230), Expect = 1.283e-20
Identity = 55/189 (29.10%), Postives = 96/189 (50.79%), Query Frame = 1 
Query:  148 FSTKSYWDKRYENEDN--YEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMK----CKYKDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANENQWTYAAKFRIQFENFMLNVHNILKRDGKFLSVSFHQPMFRLPLLIDFSNHSTPFWKIKIEEIES 696
            F +  YW+K ++      +EW     ++ E+L +Y     KVL++GCGNS LS +LY  GY++I++ D SE +I++MK     +   +  LK    DM  L +   +F ++ +KG +DAVL +E + T       Q +  +  V  +L+  G++L +S  Q       +  FS      W ++  ++ S
Sbjct:   11 FGSADYWEKFFQQRGKTAFEWYGTYLELCEVLHKYIKPKEKVLVIGCGNSELSEQLYDVGYQDIVNIDISEVVIKQMKERNGSRRPHMSFLKM---DMTQLEFPDATFQVVLDKGTLDAVLTDEEEVTLR-----QVDRMLAEVGRVLQVGGRYLCISLAQAHILKKAVGHFSREG---WMVRAHQVAS 188
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. UniProt/SwissProt
Match: sp|P0DPE0|EFMT4_MOUSE (EEF1A lysine methyltransferase 4 OS=Mus musculus OX=10090 GN=Eef1akmt4 PE=2 SV=1)

HSP 1 Score: 128.257 bits (321), Expect = 4.378e-34
Identity = 69/204 (33.82%), Postives = 108/204 (52.94%), Query Frame = 1 
Query:  163 YWDKRYENEDN---YEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCKYKDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANE-NQWTYAAKFRIQFENFMLNVHNILKRDGKFLSVSFHQPMFRLPLLIDFSNHSTPFWKIKIEEIESGFHFILYNFEKSQALHHSVNDL 762
            YWD+RY++  +   YEW         +L+       ++L+LGCGNS LSYEL+  G+ N+ S DYS  ++  M+ +Y  +  L+WE  D+  L +   SFD++ EKG +DA+LA E + W  +++     +  +  V  +L   G+F+S++   P FR    I     S   W ++     SGFHF  Y   K +AL  SV+ L
Sbjct:   25 YWDQRYKDAADSGPYEWFGDFASFRALLEPELCPEDRILVLGCGNSALSYELFLGGFPNVTSVDYSPVVVAAMQVRYAHVPSLRWETMDVRALDFPSGSFDVVLEKGTLDAMLAGEPDPWNVSSEGVHTVDQVLSEVSRLLVPGGRFISMTSAGPHFR----IRHYAQSRYDWSLRHTTYSSGFHFHFYIMHKGRAL--SVSQL 222
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. UniProt/SwissProt
Match: sp|P0DPD7|EFMT4_HUMAN (EEF1A lysine methyltransferase 4 OS=Homo sapiens OX=9606 GN=EEF1AKMT4 PE=1 SV=1)

HSP 1 Score: 127.102 bits (318), Expect = 1.168e-33
Identity = 63/199 (31.66%), Postives = 106/199 (53.27%), Query Frame = 1 
Query:  163 YWDKRYENEDN---YEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCKYKDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANE-NQWTYAAKFRIQFENFMLNVHNILKRDGKFLSVSFHQPMFRLPLLIDFSNHSTPF--WKIKIEEIESGFHFILYNFEKSQAL 741
            YWD+RY+   +   Y+W         +L+       ++L+LGCGNS LSYEL+  G+ N+ S DYS  ++  M+ ++  + +L+WE  D+  L +   SFD++ EKG +DA+LA E + WT +++     +  +  V  +L   G+F+S++   P FR        +++  +  W ++     SGFHF LY   K   L
Sbjct:   25 YWDQRYQGAADSAPYDWFGDFSSFRALLEPELRPEDRILVLGCGNSALSYELFLGGFPNVTSVDYSSVVVAAMQARHAHVPQLRWETMDVRKLDFPSASFDVVLEKGTLDALLAGERDPWTVSSEGVHTVDQVLSEVSRVLVPGGRFISMTSAAPHFRT------RHYAQAYYGWSLRHATYGSGFHFHLYLMHKGGKL 217
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. UniProt/SwissProt
Match: sp|P0DPE1|EFMT4_BOVIN (EEF1A lysine methyltransferase 4 OS=Bos taurus OX=9913 GN=EEF1AKMT4 PE=2 SV=1)

HSP 1 Score: 118.627 bits (296), Expect = 1.739e-30
Identity = 68/237 (28.69%), Postives = 115/237 (48.52%), Query Frame = 1 
Query:  163 YWDKRYENEDN---YEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCKYKDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANE-NQWTYAAKFRIQFENFMLNVHNILKRDGKFLSVSFHQPMFRLPLLIDFSNHSTPF---WKIKIEEIESGFHFILYNFEKSQALHHSVNDLISKYSKYQRTINRTISKESYNDNEDNFLST 852
            YWD+RY+   +   YEW        ++L+       ++L+LGCGNS LSYE++  G+ ++ S DYS  ++  M+ +Y  +  L+WE  D+  L +   SFD++ EKG +DA+L  E + WT +++     +  +  V  +L   G+F+S++   P FR       + H       W ++     +GF F  Y  +K + L  SV  L             T S    + + ++FLS 
Sbjct:   25 YWDQRYQGAADSAPYEWFGDFSCFRDLLEPELRPLDRILVLGCGNSALSYEIFLGGFPDVTSVDYSSVVVAAMRARYAHVPTLRWETMDVRALGFPSGSFDVVLEKGTLDALLTGEQDPWTVSSEGVHTVDQVLNEVSRVLVPAGRFISLTSAAPHFR-------TRHYAQAHYGWSLRHATYGNGFQFHFYLMQKGKEL--SVAQLAVGAQILSPPRPPTPSCFLQDSDHEDFLSA 252
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. UniProt/SwissProt
Match: sp|P0DPE2|EFCE2_BOVIN (EEF1AKMT4-ECE2 readthrough transcript protein OS=Bos taurus OX=9913 GN=EEF1AKMT4-ECE2 PE=1 SV=1)

HSP 1 Score: 103.99 bits (258), Expect = 2.132e-23
Identity = 49/150 (32.67%), Postives = 84/150 (56.00%), Query Frame = 1 
Query:  163 YWDKRYENEDN---YEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCKYKDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANE-NQWTYAAKFRIQFENFMLNVHNILKRDGKFLSV 600
            YWD+RY+   +   YEW        ++L+       ++L+LGCGNS LSYE++  G+ ++ S DYS  ++  M+ +Y  +  L+WE  D+  L +   SFD++ EKG +DA+L  E + WT +++  +   + +LN     KR  + L +
Sbjct:   25 YWDQRYQGAADSAPYEWFGDFSCFRDLLEPELRPLDRILVLGCGNSALSYEIFLGGFPDVTSVDYSSVVVAAMRARYAHVPTLRWETMDVRALGFPSGSFDVVLEKGTLDALLTGEQDPWTVSSE-GVHTVDQVLNEAGFRKRTSRLLGL 173
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. UniProt/SwissProt
Match: sp|P0DPD8|EFCE2_HUMAN (EEF1AKMT4-ECE2 readthrough transcript protein OS=Homo sapiens OX=9606 GN=EEF1AKMT4-ECE2 PE=1 SV=1)

HSP 1 Score: 103.99 bits (258), Expect = 2.502e-23
Identity = 45/125 (36.00%), Postives = 75/125 (60.00%), Query Frame = 1 
Query:  163 YWDKRYENEDN---YEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCKYKDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANE-NQWTYAAK 525
            YWD+RY+   +   Y+W         +L+       ++L+LGCGNS LSYEL+  G+ N+ S DYS  ++  M+ ++  + +L+WE  D+  L +   SFD++ EKG +DA+LA E + WT +++
Sbjct:   25 YWDQRYQGAADSAPYDWFGDFSSFRALLEPELRPEDRILVLGCGNSALSYELFLGGFPNVTSVDYSSVVVAAMQARHAHVPQLRWETMDVRKLDFPSASFDVVLEKGTLDALLAGERDPWTVSSE 149
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. TrEMBL
Match: W4ZBZ4 (Methyltransf_11 domain-containing protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1)

HSP 1 Score: 157.532 bits (397), Expect = 7.580e-43
Identity = 83/242 (34.30%), Postives = 136/242 (56.20%), Query Frame = 1 
Query:  145 NFSTKSYWDKRYENEDNYEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCKYKDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANE-NQWTYAAKFRIQFENFMLNVHNILKRDGKFLSVSFHQPMFRLPLLIDFSNHSTPFWKIKIEEIESGFHFILYNFEKSQALHHSVNDL-----ISKYSKYQRTINRTISKESYNDNEDNFLST 852
            +F+T+SYWD+R++ E+ Y+WL+K  Q +  ++++ N N ++L+LGCGNS LS E+Y  GY NI++ D+S   IEKMK K++    ++W   D+ DL +   SFD++ EKG +DA++ANE + W    +     E  +  V  +LK  G FLS++F QP FR PLL      +   W +++  +   FHF  +  EK + +     +L     + + S  Q  + R        ++E  FL+ 
Sbjct:   16 DFTTESYWDERFKEEETYDWLLKYHQFSHFVEKHVNRNERILMLGCGNSKLSLEMYEDGYHNIVNVDFSSVCIEKMKEKHQHCPIMQWMVMDIKDLKFPDCSFDVVLEKGTLDALVANERDPWNMTDEGYDVMEQSLTQVSRVLKPGGYFLSITFSQPHFRRPLLA----RTLLKWNVELMTLGDHFHFFSFAMEKGKEMSAKDKELEKESMLKRQSNAQGNVKRQYVYVKDEESEQTFLNA 253
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. TrEMBL
Match: A0A3M6T6M4 (Methyltranfer_dom domain-containing protein OS=Pocillopora damicornis OX=46731 GN=pdam_00016449 PE=4 SV=1)

HSP 1 Score: 151.754 bits (382), Expect = 1.598e-40
Identity = 72/200 (36.00%), Postives = 112/200 (56.00%), Query Frame = 1 
Query:  145 NFSTKSYWDKRYENEDNYEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCKYKDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANE-NQWTYAAKFRIQFENFMLNVHNILKRDGKFLSVSFHQPMFRLPLLIDFSNHSTPFWKIKIEEIESGFHFILYNFEKSQAL 741
            ++  + YWD+R+  EDN+EW         ++  + N + ++LILGCGNS+LS ++Y  GYRNI++ D+S  +IE MK K KD+ E++W   DM ++ +   SF++I EK  +DA++  E + W      R   +  +  V  ILK  G+F+SV+F QP FR P L     +    W I  +     FHF  Y  EK + +
Sbjct:   22 SYKQQEYWDRRFSKEDNFEWCKSYKDFEHLINEHVNRSDRILILGCGNSSLSEDMYRDGYRNIVNIDFSAVVIENMKRKCKDLTEMQWMVMDMTNMTFPEGSFEVIIEKATLDALMVEERDPWNPTGDIRNSMDCVLSQVSKILKDGGRFISVTFSQPHFRKPFLAKLQYN----WSISQQTFGESFHFFFYVMEKGRPM 217
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. TrEMBL
Match: H2Z6S3 (Methyltranfer_dom domain-containing protein OS=Ciona savignyi OX=51511 PE=4 SV=1)

HSP 1 Score: 147.517 bits (371), Expect = 1.967e-39
Identity = 78/201 (38.81%), Postives = 117/201 (58.21%), Query Frame = 1 
Query:  148 FSTKSYWDKRYENEDNYEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCKYKDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANENQ-WTYAAKFRIQFENFMLNVHNILKRDGKFLSVSFHQPMFRLPLLIDFSNHSTPFWKIKIEEI-ESG-FHFILYNFEKSQAL 741
            +  K YWD RYENED+Y+W    D    +LK + + N K+LILGCGNS  S +LY  GY+N+ + DYS   IE MK KY+++ E+ W   D+ +L ++ ++FD++ +KG +DA+L  EN  W  +       E  + NV  +LK  G+F+S++F QP FR  +L      S   W ++   I +SG F + LY   K + L
Sbjct:    8 YKEKEYWDHRYENEDSYDWFKSYDDFKNVLKDHMDKNDKILILGCGNSPFSLDLYKDGYKNVTNVDYSTVCIENMKQKYQNLSEMSWYVMDITNLQFEASTFDVVIDKGTLDALLVEENDVWNISETAFETMEAVLRNVSTVLKVGGRFVSITFSQPHFRKKILA----RSKFNWDVQTFSIGDSGCFEYFLYVMTKGKEL 204
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. TrEMBL
Match: A0A3Q0JVU6 (EEF1A lysine methyltransferase 4-like OS=Ciona intestinalis OX=7719 GN=LOC100183625 PE=4 SV=1)

HSP 1 Score: 147.902 bits (372), Expect = 3.593e-39
Identity = 76/204 (37.25%), Postives = 116/204 (56.86%), Query Frame = 1 
Query:  148 FSTKSYWDKRYENEDNYEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCKYKDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANENQWTY-AAKFRIQFENFMLNVHNILKRDGKFLSVSFHQPMFRLPLLIDFSNHSTPFWKIKIEEIESG--FHFILYNFEKSQALHHS 750
            +  K YWD+RYE E++Y+W    D    +LK + N   ++L+LGCGNS  S  LY  GYRNI++ DYS   IEKM+ K KD+ E+KW   D+ DL +   SFD++ +KG +DA+L +++ + +   K     E  + NV  +L   G+F+S++F QP+FR  L +     S   W ++   I  G    + +Y  EK + L  S
Sbjct:    8 YKEKEYWDERYETEESYDWFKGYDDFKSVLKNHMNTQDRILMLGCGNSPFSEHLYKDGYRNIVNIDYSHICIEKMEAKCKDLAEMKWLVMDIMDLKFGDASFDLVIDKGTLDAILTDQSGFGHLCEKAFDAIEVVLTNVSRVLVNGGRFVSITFAQPLFRKKLYV----RSIFGWNVQTFSIGEGGCLQYFVYVMEKGKQLSDS 207
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. TrEMBL
Match: F7AMD9 (Methyltransf_11 domain-containing protein OS=Ciona intestinalis OX=7719 PE=4 SV=2)

HSP 1 Score: 147.517 bits (371), Expect = 3.824e-39
Identity = 76/204 (37.25%), Postives = 116/204 (56.86%), Query Frame = 1 
Query:  148 FSTKSYWDKRYENEDNYEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCKYKDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANENQWTY-AAKFRIQFENFMLNVHNILKRDGKFLSVSFHQPMFRLPLLIDFSNHSTPFWKIKIEEIESG--FHFILYNFEKSQALHHS 750
            +  K YWD+RYE E++Y+W    D    +LK + N   ++L+LGCGNS  S  LY  GYRNI++ DYS   IEKM+ K KD+ E+KW   D+ DL +   SFD++ +KG +DA+L +++ + +   K     E  + NV  +L   G+F+S++F QP+FR  L +     S   W ++   I  G    + +Y  EK + L  S
Sbjct:    4 YKEKEYWDERYETEESYDWFKGYDDFKSVLKNHMNTQDRILMLGCGNSPFSEHLYKDGYRNIVNIDYSHICIEKMEAKCKDLAEMKWLVMDIMDLKFGDASFDLVIDKGTLDAILTDQSGFGHLCEKAFDAIEVVLTNVSRVLVNGGRFVSITFAQPLFRKKLYV----RSIFGWNVQTFSIGEGGCLQYFVYVMEKGKQLSDS 203
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Cavefish
Match: ece2a (endothelin-converting enzyme 2-like [Source:NCBI gene;Acc:103031349])

HSP 1 Score: 122.479 bits (306), Expect = 5.826e-33
Identity = 63/195 (32.31%), Postives = 99/195 (50.77%), Query Frame = 1 
Query:  163 YWDKRYENEDNYEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCKYKDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANE-NQWTYAAKFRIQFENFMLNVHNILKRDGKFLSVSFHQPMFRLPLLIDFSNHSTPF-WKIKIEEIESGFHFILYNFEKSQAL 741
            YW+ RY+ E+++EW     +   +L ++      +L+LGCGNS LS ++   GY +I + DYS   +E M  ++ D   L W C D+  L +   SFD++ EKG +DA+L +E + W  +          +  +  +LK  G+F+SV+F QP FR  L        T + W I        FH+ LY   K + L
Sbjct:   19 YWNTRYQTEESFEWFGDFSRFQHLLVQHVGRYDSILMLGCGNSALSTDMCQAGYTSITNVDYSSVCVETMAQRHSDCAGLSWVCMDIRRLAFPDASFDVVIEKGTLDAMLVDERDPWNVSDSSAHLLHQVLSEISRVLKPGGRFISVTFAQPHFRKRLYA-----RTEYDWSINHHHYGEAFHYFLYVLTKGEEL 208
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Cavefish
Match: mettl13 (eEF1A lysine and N-terminal methyltransferase [Source:NCBI gene;Acc:103031783])

HSP 1 Score: 81.2629 bits (199), Expect = 1.011e-16
Identity = 53/181 (29.28%), Postives = 89/181 (49.17%), Query Frame = 1 
Query:  148 FSTKSYWDK--RYENEDNYEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCK-YKDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANENQWTYAAKFRIQFENFMLNVHNILKRDGKFLSVSFHQPMFRLPLLIDFSNHSTPFWKIKI 681
            FS+  YW++  R   E  +EW    + +  +L +Y     KVL++GCGNS LS +LY  GYR++ + D SET++  M  +  +   +L +E  D     Y+  S+    +KG +DA +A+E +   A +        +  V  +L   G+++ V+  Q       +  FSN     W I+I
Sbjct:   11 FSSADYWERFFRKRGEKAFEWYGDYNSLCGVLHKYIKPKDKVLVVGCGNSELSEQLYDVGYRHLTNIDISETVVSHMNQRNVQRRPDLIFEQVDATQTGYENGSYQAALDKGTLDA-MASEEEGALAGR-------MLAEVARVLTVGGRYVCVTLAQEHVIKLAVEHFSNAG---WAIRI 180
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Cavefish
Match: mettl13 (eEF1A lysine and N-terminal methyltransferase [Source:NCBI gene;Acc:103031783])

HSP 1 Score: 81.2629 bits (199), Expect = 1.011e-16
Identity = 53/181 (29.28%), Postives = 89/181 (49.17%), Query Frame = 1 
Query:  148 FSTKSYWDK--RYENEDNYEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCK-YKDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANENQWTYAAKFRIQFENFMLNVHNILKRDGKFLSVSFHQPMFRLPLLIDFSNHSTPFWKIKI 681
            FS+  YW++  R   E  +EW    + +  +L +Y     KVL++GCGNS LS +LY  GYR++ + D SET++  M  +  +   +L +E  D     Y+  S+    +KG +DA +A+E +   A +        +  V  +L   G+++ V+  Q       +  FSN     W I+I
Sbjct:   11 FSSADYWERFFRKRGEKAFEWYGDYNSLCGVLHKYIKPKDKVLVVGCGNSELSEQLYDVGYRHLTNIDISETVVSHMNQRNVQRRPDLIFEQVDATQTGYENGSYQAALDKGTLDA-MASEEEGALAGR-------MLAEVARVLTVGGRYVCVTLAQEHVIKLAVEHFSNAG---WAIRI 180
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Cavefish
Match: eef1akmt2 (EEF1A lysine methyltransferase 2 [Source:NCBI gene;Acc:503749])

HSP 1 Score: 55.8398 bits (133), Expect = 7.036e-9
Identity = 42/163 (25.77%), Postives = 76/163 (46.63%), Query Frame = 1 
Query:  148 FSTKSYWDKRYENE-DNYEWLIKIDQVNE--------ILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMK--CKYKDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANENQWTYAAKFRIQFENFMLNVHNILKRDGKFLSVS 603
              TK YWD  Y+ E   Y+ +  + ++ E        ++K+    NA +L +G GN     EL  +G+ N+   DYS   IE  +   + + ++ +K +  D  +   +   FD+  +KG  DA+  N +    AAK +     ++ ++  +LK  G F+  S
Sbjct:   19 LGTKEYWDDAYKRELQTYKDIGDVGEIWESMHRVLKWMVKQNIPKNAAILDIGTGNGVFLVELAKEGFDNLTGIDYSNASIELTRNILEEEGLVNIKVQEQDFLNPSAELKDFDVCIDKGTFDAISLNPDGQN-AAKLQ-----YVSSLTTVLKPQGHFIITS 175
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Nematostella
Match: EDO44209 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RW62])

HSP 1 Score: 134.42 bits (337), Expect = 2.511e-38
Identity = 69/200 (34.50%), Postives = 109/200 (54.50%), Query Frame = 1 
Query:  145 NFSTKSYWDKRYENEDNYEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCKYKDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVL-ANENQWTYAAKFRIQFENFMLNVHNILKRDGKFLSVSFHQPMFRLPLLIDFSNHSTPFWKIKIEEIESGFHFILYNFEKSQAL 741
            ++  K YW+ R+  ED +EW     +   +L+ +     ++LILGCGNS LS ++Y +GY +I + DYS  +IE MK K   +  ++W+  D+  L +  NSFD++ EK  +DA+L A ++ W  + +     E  +  V  IL+  G F+S++F QP FRLP L      S   W I ++     FHF  +  EK + L
Sbjct:    9 SYKDKEYWNNRFAKEDTFEWCKSYKEFRHLLRGHVRTCDRILILGCGNSGLSEDMYNEGYTDITNIDYSPIVIENMKRKCHAMRGMEWKVMDITKLDFPPNSFDVVIEKATLDALLVAEKDPWNPSVEALKTMECVLSKVSEILEPAGHFMSMTFSQPNFRLPFLA----RSCYNWSISVQTYGESFHFFFFLMEKGKQL 204
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Nematostella
Match: EDO44200 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RWN9])

HSP 1 Score: 71.633 bits (174), Expect = 7.295e-15
Identity = 51/180 (28.33%), Postives = 81/180 (45.00%), Query Frame = 1 
Query:  145 NFSTKSYWDKRYENE---DNYEWLIKIDQVNEILKRYANNNAKV--LILGCGNSNLSYEL--YAKGYRNIISTDYSETIIEKMKCKYK----DIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANENQWTYAAKFRIQFENFMLNVHNILKRDGKFLSVSFHQPMFRLPLLIDFSN 651
            N S  S+W+K Y++    + +EW +    V+  L +Y + ++ +  L LGCG S    +L  Y +G   +   D+SE  I+ M+   +    D         ++ DLP+    FDII +KG  DAVL +    T        F   ++    +LK +G  L  S   P  R+ LL   S 
Sbjct:    5 NLSDMSFWEKFYKSRGPNNTFEWFLDFQDVHNSLDKYIHKDSHINTLDLGCGTSEFCIQLFYYLRGNCKVAGIDFSEEAIQVMRNLLRQHGLDDSVFSLHVGNVLDLPFSRECFDIIIDKGTADAVLRSPAAET-------AFCAVLVEACRVLKSEGTILQFSDESPEVRMDLLTKASQ 177
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Nematostella
Match: EDO48242 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJC9])

HSP 1 Score: 73.9442 bits (180), Expect = 9.611e-15
Identity = 50/182 (27.47%), Postives = 90/182 (49.45%), Query Frame = 1 
Query:  148 FSTKSYWDKRYENEDNYEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCKY-KDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANENQWTYAAKFRIQFENFMLNVHNILKRDGKFLSVSFHQPMFRLPLLIDFSNHSTPFWKIKIEEI 690
            F T+ +     E    YEW  + + + +++ +Y   N ++L L CG+S L   LY  GYRNIIS D SE +I+KM+ +      ++++   D+ DL YD  SF+++F+K  +D    N ++         + +     +  +LK  G+F+  +  Q      LL  FS      W +++ ++
Sbjct:   14 FGTEQWNKLMKEVSRPYEWHSEYEILCDLMHKYVKLNDRLLRLACGDSKLGENLYDVGYRNIISVDSSEKVIKKMRKRNDSGKRDMEYTRMDVTDLKYDDESFNVVFDKQWLDYTFTNTSEDILK-----KVDKTFAEIQRVLKVGGRFIVCTLAQDHILDKLLAHFSQG----WLVRVHKL 186
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Nematostella
Match: EDO28352 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T6Q3])

HSP 1 Score: 56.225 bits (134), Expect = 5.530e-9
Identity = 29/76 (38.16%), Postives = 44/76 (57.89%), Query Frame = 1 
Query:  148 FSTKSYWDKRYENEDNYEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMK 375
            F T+ +     E    YEW  + + + +++ +Y   N ++L L CG+S L   LY  GYRNIIS D SE +I+KM+
Sbjct:   14 FGTEQWNKLMKEVSRPYEWHSEYEILCDLMHKYVKLNDRLLRLACGDSKLGENLYDVGYRNIISVDSSEKVIKKMR 89
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Nematostella
Match: EDO48155 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKE2])

HSP 1 Score: 51.2174 bits (121), Expect = 1.098e-7
Identity = 40/159 (25.16%), Postives = 71/159 (44.65%), Query Frame = 1 
Query:  148 FSTKSYWDKRYENE--------DNYEWLIKIDQVNEILK-----RYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIE-KMKCKYKDIMELKWECHDMFDL---PYDWNSFDIIFEKGVIDAVLANENQWTYAAKFRIQFENFMLNVHNIL 573
              TK YWD  YE E        D  E       +N ++K        + N+ +L +GCGN  L   L    Y++++  DYS   I+  +    ++ + +K+   D+ +L   P +  +FD+  +KG  DA+  N +      +  I+  + +L  H +L
Sbjct:   18 LGTKQYWDSAYETELSNFDDHGDVGEIWFGEGCLNRMIKWIKKCPRISKNSSILDVGCGNGMLLVPLAQDNYKDLLGIDYSAAAIKLAISVAEQESVNIKFMECDILELRGGPLEEKTFDMCLDKGTYDAISLNPDDSLACRQKYIKSVSELLRPHALL 176
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Medaka
Match: ece2a (methyltransferase-like protein 13-like [Source:NCBI gene;Acc:101156439])

HSP 1 Score: 119.013 bits (297), Expect = 1.292e-31
Identity = 60/194 (30.93%), Postives = 97/194 (50.00%), Query Frame = 1 
Query:  163 YWDKRYENEDNYEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCKYKDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANE-NQWTYAAKFRIQFENFMLNVHNILKRDGKFLSVSFHQPMFRLPLLIDFSNHSTPFWKIKIEEIESGFHFILYNFEKSQAL 741
            YWD+RY+ E +Y+WL    +   +L++       +L+LGCGNS+LS ++Y  GY NI + DYS   I+ M  +Y     + W   D+  L +   SFD+I EK  +DA++ +E   W  + +        +  +   LK  G+F+S++F QP FR  L       +   W I+      GF +  Y   K + +
Sbjct:   16 YWDERYKTEQSYDWLGSFSKFQHLLEKVVKKEDSILMLGCGNSSLSGDMYDAGYHNITNIDYSSVCIDTMSARYSSCPSMSWHQMDVRKLSFCDASFDVIIEKATLDAIMVDEKTPWELSKETANFIHQALTEISRCLKPGGRFISITFAQPFFRKRLYA----RTQYSWSIQHSSYGDGFEYFFYVMTKGERM 205
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Medaka
Match: mettl13 (eEF1A lysine and N-terminal methyltransferase [Source:NCBI gene;Acc:110014767])

HSP 1 Score: 76.6406 bits (187), Expect = 4.155e-15
Identity = 49/158 (31.01%), Postives = 80/158 (50.63%), Query Frame = 1 
Query:  148 FSTKSYWDKRYENEDN--YEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCK-YKDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANENQWTYAAKFRIQFENFMLNVHNILKRDGKFLSVSFHQ 612
            FS+  YWDK +++  +  +EW    +++  IL +Y     KVL+LGCGNS LS +LY  GY+++ + D SET++  M  +       L +   D     Y+  SF +  +KG +DA+ A E      A  R      +  V  +L   G+++ V+  Q
Sbjct:   11 FSSAEYWDKFFKSRGDKAFEWYGDYNKLCGILHKYIKVQDKVLVLGCGNSELSEQLYDVGYKHLTNIDISETVVTHMNQRNAARRPGLSFHRVDATQTLYEDASFQVSLDKGTLDAMAAEEG----GALAR----RMLQEVSRVLSVGGRYICVTLAQ 160
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Medaka
Match: eef1akmt2 (EEF1A lysine methyltransferase 2 [Source:NCBI gene;Acc:101168144])

HSP 1 Score: 50.8322 bits (120), Expect = 4.947e-7
Identity = 43/168 (25.60%), Postives = 71/168 (42.26%), Query Frame = 1 
Query:  148 FSTKSYWDKRYENEDNYEWLIKIDQVNEI------LKRYAN--------NNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMK--CKYKDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANENQWTYAAKFRIQFENFMLNVHNILKRDGKFLSVS 603
              TK YW++ Y+ E   E    I  V EI      + R            NA +L +G GN     EL   G++N+   DYS   +E  +   + + + ++  +  D  +   +   FD+  +KG  DA+  N N    A K  +Q       + + LK +G F S++
Sbjct:   32 LGTKEYWEEMYQKE--LETFKDIGDVGEIWFGEESMSRVLGWMQTAKIPENAAILDIGTGNGAFLVELAKHGFKNLTGVDYSPASVELARNVLQTECLSDITVKEVDFLNCNRELKEFDVCIDKGTFDAISLNPNNSKEAKKLYVQ------ALRDALKENG-FFSIT 190
[Close]
BLAST of Methyltransf_11 domain-containing protein vs. Planmine SMEST
Match: SMESG000007804.1 (SMESG000007804.1)

HSP 1 Score: 486.108 bits (1250), Expect = 7.440e-176
Identity = 236/238 (99.16%), Postives = 237/238 (99.58%), Query Frame = 1 
Query:  142 MNFSTKSYWDKRYENEDNYEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCKYKDIMELKWECHDMFDLPYDWNSFDIIFEKGVIDAVLANENQWTYAAKFRIQFENFMLNVHNILKRDGKFLSVSFHQPMFRLPLLIDFSNHSTPFWKIKIEEIESGFHFILYNFEKSQALHHSVNDLISKYSKYQRTINRTISKESYNDNEDNFLSTG 855
            MNFSTKSYWDKRYENEDNYEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCKYKDIMELKWECHDMF+LPYDWNSFDIIFEKGVIDAVLANENQWTYAAKFRIQFENFMLNVHNILKRDGKFLSVSFHQPMFRLPLLIDFSNHSTPFWKIKIEEIESGFHFILYNFEKS ALHHSVNDLISKYSKYQRTINRTISKESYNDNEDNFLSTG
Sbjct:    1 MNFSTKSYWDKRYENEDNYEWLIKIDQVNEILKRYANNNAKVLILGCGNSNLSYELYAKGYRNIISTDYSETIIEKMKCKYKDIMELKWECHDMFNLPYDWNSFDIIFEKGVIDAVLANENQWTYAAKFRIQFENFMLNVHNILKRDGKFLSVSFHQPMFRLPLLIDFSNHSTPFWKIKIEEIESGFHFILYNFEKSPALHHSVNDLISKYSKYQRTINRTISKESYNDNEDNFLSTG 238
The following BLAST results are available for this feature:
BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 4
Match NameE-valueIdentityDescription
EEF1AKMT42.431e-3431.66EEF1A lysine methyltransferase 4 [Source:HGNC Symb... [more]
ECE25.210e-2436.00endothelin converting enzyme 2 [Source:HGNC Symbol... [more]
EEF1AKNMT9.234e-2228.80eEF1A lysine and N-terminal methyltransferase [Sou... [more]
EEF1AKNMT2.834e-1831.51eEF1A lysine and N-terminal methyltransferase [Sou... [more]
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BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
C17E4.111.673e-3431.92pep chromosome:WBcel235:I:9419973:9420813:-1 gene:... [more]
C01B10.84.662e-1425.50pep chromosome:WBcel235:IV:6635039:6638155:1 gene:... [more]
C01B10.84.662e-1425.50pep chromosome:WBcel235:IV:6635089:6638155:1 gene:... [more]
F29B9.15.393e-925.29Protein-lysine N-methyltransferase CELE_F29B9.1 [... [more]
F29B9.15.393e-925.29Protein-lysine N-methyltransferase CELE_F29B9.1 [... [more]
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BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
CG26148.175e-1527.22gene:FBgn0032873 transcript:FBtr0339520[more]
CG26148.824e-1527.22gene:FBgn0032873 transcript:FBtr0081388[more]
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BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ece2a3.996e-3735.05endothelin converting enzyme 2a [Source:ZFIN;Acc:Z... [more]
ece2a1.286e-3635.05endothelin converting enzyme 2a [Source:ZFIN;Acc:Z... [more]
ece2a8.204e-2637.72endothelin converting enzyme 2a [Source:ZFIN;Acc:Z... [more]
mettl131.883e-1728.48methyltransferase like 13 [Source:NCBI gene;Acc:55... [more]
mettl138.583e-1728.48methyltransferase like 13 [Source:NCBI gene;Acc:55... [more]
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BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3
Match NameE-valueIdentityDescription
bsk1467.338e-2829.41brain specific kinase 146 [Source:Xenbase;Acc:XB-G... [more]
eef1aknmt1.053e-1626.74methyltransferase like 13 [Source:NCBI gene;Acc:73... [more]
eef1aknmt1.192e-1626.74methyltransferase like 13 [Source:NCBI gene;Acc:73... [more]
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BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Eef1akmt46.259e-3533.82EEF1A lysine methyltransferase 4 [Source:MGI Symbo... [more]
Eef1akmt44.219e-2638.79EEF1A lysine methyltransferase 4 [Source:MGI Symbo... [more]
Gm493336.179e-2438.79predicted gene, 49333 [Source:MGI Symbol;Acc:MGI:6... [more]
Gm493336.973e-2438.79predicted gene, 49333 [Source:MGI Symbol;Acc:MGI:6... [more]
Eef1aknmt1.283e-2029.10EEF1A lysine and N-terminal methyltransferase [Sou... [more]
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BLAST of Methyltransf_11 domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P0DPE0|EFMT4_MOUSE4.378e-3433.82EEF1A lysine methyltransferase 4 OS=Mus musculus O... [more]
sp|P0DPD7|EFMT4_HUMAN1.168e-3331.66EEF1A lysine methyltransferase 4 OS=Homo sapiens O... [more]
sp|P0DPE1|EFMT4_BOVIN1.739e-3028.69EEF1A lysine methyltransferase 4 OS=Bos taurus OX=... [more]
sp|P0DPE2|EFCE2_BOVIN2.132e-2332.67EEF1AKMT4-ECE2 readthrough transcript protein OS=B... [more]
sp|P0DPD8|EFCE2_HUMAN2.502e-2336.00EEF1AKMT4-ECE2 readthrough transcript protein OS=H... [more]
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BLAST of Methyltransf_11 domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
W4ZBZ47.580e-4334.30Methyltransf_11 domain-containing protein OS=Stron... [more]
A0A3M6T6M41.598e-4036.00Methyltranfer_dom domain-containing protein OS=Poc... [more]
H2Z6S31.967e-3938.81Methyltranfer_dom domain-containing protein OS=Cio... [more]
A0A3Q0JVU63.593e-3937.25EEF1A lysine methyltransferase 4-like OS=Ciona int... [more]
F7AMD93.824e-3937.25Methyltransf_11 domain-containing protein OS=Ciona... [more]
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BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
ece2a5.826e-3332.31endothelin-converting enzyme 2-like [Source:NCBI g... [more]
mettl131.011e-1629.28eEF1A lysine and N-terminal methyltransferase [Sou... [more]
mettl131.011e-1629.28eEF1A lysine and N-terminal methyltransferase [Sou... [more]
eef1akmt27.036e-925.77EEF1A lysine methyltransferase 2 [Source:NCBI gene... [more]
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BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO442092.511e-3834.50Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO442007.295e-1528.33Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO482429.611e-1527.47Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO283525.530e-938.16Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO481551.098e-725.16Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Methyltransf_11 domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ece2a1.292e-3130.93methyltransferase-like protein 13-like [Source:NCB... [more]
mettl134.155e-1531.01eEF1A lysine and N-terminal methyltransferase [Sou... [more]
eef1akmt24.947e-725.60EEF1A lysine methyltransferase 2 [Source:NCBI gene... [more]
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BLAST of Methyltransf_11 domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000007804.17.440e-17699.16SMESG000007804.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30021372 ID=SMED30021372|Name=Methyltransf_11 domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=928bp
GTTTTGTTGGAGTGATTTATTAAAAGTTTAAATTATTTTGTCACTAATTT
TTTAGTGAACTTCAAATTCAAATTAATTTTAATAAATATTTTGATTAGAT
TCCTATTATTGTAAATCTTTTTAAAGTCTTTAATTTATTTAATGAATTTT
TCAACTAAATCTTATTGGGATAAACGTTATGAAAATGAAGATAATTATGA
GTGGCTAATAAAGATTGATCAAGTAAACGAGATTTTAAAGCGATATGCAA
ATAATAATGCAAAAGTATTGATACTTGGTTGTGGTAATAGCAATTTAAGT
TATGAATTATATGCCAAAGGTTATCGAAACATTATTTCTACTGATTATTC
TGAAACAATAATTGAAAAGATGAAATGTAAATATAAAGATATAATGGAGT
TAAAGTGGGAATGTCATGACATGTTTGATTTACCTTATGATTGGAATTCT
TTTGATATTATTTTTGAGAAAGGTGTAATTGATGCAGTTTTAGCCAATGA
GAACCAGTGGACGTATGCAGCAAAATTTCGAATTCAATTTGAAAATTTTA
TGTTGAATGTACACAATATTTTGAAGAGAGATGGTAAATTTTTGTCTGTT
TCTTTTCATCAGCCAATGTTTCGTTTACCTTTACTTATTGATTTTTCCAA
TCACAGTACCCCTTTTTGGAAAATTAAAATTGAAGAAATCGAATCTGGAT
TTCATTTTATTCTCTACAATTTCGAGAAAAGTCAAGCGTTACATCATTCT
GTTAATGATTTAATTTCAAAATATTCCAAATATCAGCGAACAATAAATAG
AACAATTTCAAAAGAAAGCTACAATGATAACGAGGATAATTTCCTCTCTA
CGGGATTTGAGCTCTAAATATTATTTTCGTTATTTTGAAAATTGTTTTTA
AAAAATTATTAAACAGCTTTTAATTAAA
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protein sequence of SMED30021372-orf-1

>SMED30021372-orf-1 ID=SMED30021372-orf-1|Name=SMED30021372-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=242bp
MNFSTKSYWDKRYENEDNYEWLIKIDQVNEILKRYANNNAKVLILGCGNS
NLSYELYAKGYRNIISTDYSETIIEKMKCKYKDIMELKWECHDMFDLPYD
WNSFDIIFEKGVIDAVLANENQWTYAAKFRIQFENFMLNVHNILKRDGKF
LSVSFHQPMFRLPLLIDFSNHSTPFWKIKIEEIESGFHFILYNFEKSQAL
HHSVNDLISKYSKYQRTINRTISKESYNDNEDNFLSTGFEL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000101muscle cell
PLANA:0000142posterior region of the whole animal
Vocabulary: INTERPRO
TermDefinition
IPR041698Methyltransf_25
IPR025714Methyltranfer_dom
IPR029063SAM-dependent_MTases
Vocabulary: biological process
TermDefinition
GO:0008152metabolic process
GO:0032259methylation
Vocabulary: molecular function
TermDefinition
GO:0008168methyltransferase activity
GO:0016740transferase activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableGENE3DG3DSA:3.40.50.150coord: 1..212
e-value: 3.5E-51
score: 175.4
NoneNo IPR availablePANTHERPTHR12176UNCHARACTERIZEDcoord: 4..218
NoneNo IPR availablePANTHERPTHR12176:SF57EEF1A LYSINE METHYLTRANSFERASE 4coord: 4..218
NoneNo IPR availableCDDcd02440AdoMet_MTasescoord: 41..156
e-value: 3.8335E-5
score: 39.7207
IPR041698Methyltransferase domain 25PFAMPF13649Methyltransf_25coord: 42..119
e-value: 6.4E-10
score: 39.6
IPR029063S-adenosyl-L-methionine-dependent methyltransferaseSUPERFAMILYSSF53335S-adenosyl-L-methionine-dependent methyltransferasescoord: 4..159