Cyclin domain protein
Overview
Neoblast Clusters
Zeng et. al., 2018
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny AppEmbryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30021342 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 6
Homology
BLAST of Cyclin domain protein vs. Ensembl Human
Match: CCNB1 (cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579]) HSP 1 Score: 101.293 bits (251), Expect = 2.647e-22 Identity = 74/248 (29.84%), Postives = 117/248 (47.18%), Query Frame = 1 Query: 742 EYYPYMFKYLYEREREIKFNKNYLALNGFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGL-LACVEIIDTNLMEAFCNF-MFDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEMLI-NIFISTKYTFK--AVKEKYS 1470 EY ++ YL + E E YL + R L+DWL++VQ+ ++ ET+ + V +ID F + K QLVG+ M IA K + + P I +F ++T++ Y + QME +L LNF + P+P HF R + V++ L + M D ++H S +A A +A I + WT LQHY Y+ +E +L M+ L N+ + + K VK KY+ Sbjct: 169 EYVKDIYAYLRQLEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMVH-----FPPSQIAAGAFCLALKIL--DNGEWTPTLQHYLSYT----EESLLPVMQHLAKNVVMVNQGLTKHMTVKNKYA 405
BLAST of Cyclin domain protein vs. Ensembl Human
Match: CCNB2 (cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580]) HSP 1 Score: 99.7525 bits (247), Expect = 5.890e-22 Identity = 72/274 (26.28%), Postives = 131/274 (47.81%), Query Frame = 1 Query: 742 EYYPYMFKYLYEREREIKFNKNYLALNGFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNLMEAFCNFM----FDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEMLINIF-ISTKYT-FKAVKEKYSLNVKKAIAKNDKL--INFIEDLNSK 1539 +Y +++YL + E N ++L R L+DWL++V ++ ETL + V ++D F + + + QLVGI +L+A K + F P I++F Y+T++ Y + +ME ++L++L F + P+P HF R A ++ + + + + +D++ HP+ +SC S + + W Q+YT Y+ ++ E + M N+ ++ T F A+K KY+ + KL I+ I LNSK Sbjct: 133 DYVKDIYQYLRQLEVLQSINPHFLDGRDINGRMRAILVDWLVQVHSKFRLLQETLYMCVGIMDRFLQVQPVSRKKLQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLIDYDMVHYHPSKVAAAASCLSQKVLGQGK---------WNLKQQYYTGYTENEVLE---VMQHMAKNVVKVNENLTKFIAIKNKYA---------SSKLLKISMIPQLNSK 385
BLAST of Cyclin domain protein vs. Ensembl Human
Match: CCNB1 (cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579]) HSP 1 Score: 99.3673 bits (246), Expect = 8.650e-22 Identity = 68/226 (30.09%), Postives = 107/226 (47.35%), Query Frame = 1 Query: 742 EYYPYMFKYLYEREREIKFNKNYLALNGFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGL-LACVEIIDTNLMEAFCNF-MFDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEML 1413 EY ++ YL + E E YL + R L+DWL++VQ+ ++ ET+ + V +ID F + K QLVG+ M IA K + + P I +F ++T++ Y + QME +L LNF + P+P HF R + V++ L + M D ++H S +A A +A I + WT LQHY Y+ +E +L M+ L Sbjct: 169 EYVKDIYAYLRQLEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMVH-----FPPSQIAAGAFCLALKIL--DNGEWTPTLQHYLSYT----EESLLPVMQHL 383
BLAST of Cyclin domain protein vs. Ensembl Human
Match: CCNA1 (cyclin A1 [Source:HGNC Symbol;Acc:HGNC:1577]) HSP 1 Score: 98.5969 bits (244), Expect = 1.511e-21 Identity = 83/282 (29.43%), Postives = 139/282 (49.29%), Query Frame = 1 Query: 652 LLLIRTVTPKSKEMSNLSEQFD---MKIDE-NFFEYYPYMFKYLYEREREIKFNKNYLALN-GFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLL---ACVEIIDTNLMEAFCNFMFDLIILHPASPGIR--SSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEMLINIFISTKYTFKAVKEKY 1467 LL TV+P + S LS+ D + D N EY +++YL E E + +Y+ E RT L+DWL++V K+ ETL + V +D F S + + QLVG A ML+A K + + P + EF Y+T+D Y +++ME ++L+ L F + VP N F + L CV E ++ +L +L A P ++ S +AAA +A + + W + L +T YS++++ C+ + ++I + +A++EKY Sbjct: 132 LLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRT------ENLAKYVAELSLLE-ADPFLKYLPSLIAAAAFCLANYTVNKHF--WPETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQ---QAIREKY 401
BLAST of Cyclin domain protein vs. Ensembl Human
Match: CCNA1 (cyclin A1 [Source:HGNC Symbol;Acc:HGNC:1577]) HSP 1 Score: 98.5969 bits (244), Expect = 1.511e-21 Identity = 83/282 (29.43%), Postives = 139/282 (49.29%), Query Frame = 1 Query: 652 LLLIRTVTPKSKEMSNLSEQFD---MKIDE-NFFEYYPYMFKYLYEREREIKFNKNYLALN-GFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLL---ACVEIIDTNLMEAFCNFMFDLIILHPASPGIR--SSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEMLINIFISTKYTFKAVKEKY 1467 LL TV+P + S LS+ D + D N EY +++YL E E + +Y+ E RT L+DWL++V K+ ETL + V +D F S + + QLVG A ML+A K + + P + EF Y+T+D Y +++ME ++L+ L F + VP N F + L CV E ++ +L +L A P ++ S +AAA +A + + W + L +T YS++++ C+ + ++I + +A++EKY Sbjct: 132 LLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRT------ENLAKYVAELSLLE-ADPFLKYLPSLIAAAAFCLANYTVNKHF--WPETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQ---QAIREKY 401
BLAST of Cyclin domain protein vs. Ensembl Celegans
Match: cya-1 (G2/mitotic-specific cyclin-A1 [Source:UniProtKB/Swiss-Prot;Acc:P34638]) HSP 1 Score: 78.9518 bits (193), Expect = 2.131e-15 Identity = 64/252 (25.40%), Postives = 112/252 (44.44%), Query Frame = 1 Query: 742 EYYPYMFKYLYEREREIKFNKNYLALNG-FEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNLMEAFCNFMFDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEMLINIFISTKYTFKAVKEKYSLNVKKAIA 1494 E++P + KY+ R+ + + + + E RT L+DW V ET + V L+D S+ I K +QLVG M+IA K + F P I++F +T++ Y+ ++ MER +L K +F V +P + F G + T M +++ +L ++ R S +AAA A + SW + + T S + + M +N ++ FK++ YS + +A Sbjct: 211 EFFPDIIKYMLHRQTKNRASHECFDIQSQVNEEMRTILIDWFSDVVKEYNFQKETFHLAVSLVDRALSMFNIDKMRFQLVGTTSMMIAVKYEEIFPPEIEDFALITDNTYRVPDILLMERFLLGKFDFVVAMPTSSWF---GTCFAKRMNFTKKMRNTVHYLLELSLIDVHFLRYRPSDIAAAACCFAN--LQADVESWPQKMVDDTGISTEDFVDVLRDLHRMYLN---ASTADFKSIFYNYSETAQMEVA 454
BLAST of Cyclin domain protein vs. Ensembl Celegans
Match: cyb-2.2 (CYclin B [Source:UniProtKB/TrEMBL;Acc:Q9BLB5]) HSP 1 Score: 76.2554 bits (186), Expect = 8.426e-15 Identity = 37/139 (26.62%), Postives = 74/139 (53.24%), Query Frame = 1 Query: 721 KIDENFFEYYPYMFKYLYEREREIKFNKNYLALNGFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVP 1137 K++E F ++ YL E++ + +++ R L+DWL++V L +T ETL + + ++D ++ K+ +QL+G+A + +A K + P I E+ +TE+ + ++ ME+ +L LNF ++ P Sbjct: 45 KLEEEFNCMAEDIYNYLVHHEKKYVLDDSFINGGNVNSKMRRILVDWLVQVHLRFHLTPETLHLTIFVLDRIIVKNIVSKAEFQLLGVAALFVASKFEDIYLPDILEYELITENTFSKKQILAMEQTILNALNFDLSCP 183
BLAST of Cyclin domain protein vs. Ensembl Celegans
Match: cyb-2.2 (CYclin B [Source:UniProtKB/TrEMBL;Acc:Q9BLB5]) HSP 1 Score: 76.2554 bits (186), Expect = 8.426e-15 Identity = 37/139 (26.62%), Postives = 74/139 (53.24%), Query Frame = 1 Query: 721 KIDENFFEYYPYMFKYLYEREREIKFNKNYLALNGFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVP 1137 K++E F ++ YL E++ + +++ R L+DWL++V L +T ETL + + ++D ++ K+ +QL+G+A + +A K + P I E+ +TE+ + ++ ME+ +L LNF ++ P Sbjct: 45 KLEEEFNCMAEDIYNYLVHHEKKYVLDDSFINGGNVNSKMRRILVDWLVQVHLRFHLTPETLHLTIFVLDRIIVKNIVSKAEFQLLGVAALFVASKFEDIYLPDILEYELITENTFSKKQILAMEQTILNALNFDLSCP 183
BLAST of Cyclin domain protein vs. Ensembl Celegans
Match: cyb-1 (G2/mitotic-specific cyclin-B1 [Source:UniProtKB/Swiss-Prot;Acc:Q10653]) HSP 1 Score: 73.559 bits (179), Expect = 6.538e-14 Identity = 41/164 (25.00%), Postives = 84/164 (51.22%), Query Frame = 1 Query: 649 QLLLIRTVTPKSKEMSNLSEQFDMKIDEN-FFEYYPYMFKYLYEREREIKFNKNYLALNGFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVP 1137 ++L ++ P E + S++ +++ E ++KYL E++ + ++ R L+DWL++V + +T ETL + V ++D + K+ QL+GI+ M +A K + + P I ++ ++TE+ Y ++ ME+ +L LNF ++ P Sbjct: 45 EILALKPSNPAPVETAQKSQRINLQDAETKCLAMADDIYKYLVHHEKKYLLEECFMEGGEPTPKMRRILVDWLVQVHVRFHLTPETLHLTVFILDRMLQKKVTSKADLQLLGISAMFVASKFEEVYLPDIHDYEFITENTYSKKQILAMEQTILNSLNFDLSCP 208
BLAST of Cyclin domain protein vs. Ensembl Celegans
Match: cyb-1 (G2/mitotic-specific cyclin-B1 [Source:UniProtKB/Swiss-Prot;Acc:Q10653]) HSP 1 Score: 73.559 bits (179), Expect = 6.538e-14 Identity = 41/164 (25.00%), Postives = 84/164 (51.22%), Query Frame = 1 Query: 649 QLLLIRTVTPKSKEMSNLSEQFDMKIDEN-FFEYYPYMFKYLYEREREIKFNKNYLALNGFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVP 1137 ++L ++ P E + S++ +++ E ++KYL E++ + ++ R L+DWL++V + +T ETL + V ++D + K+ QL+GI+ M +A K + + P I ++ ++TE+ Y ++ ME+ +L LNF ++ P Sbjct: 45 EILALKPSNPAPVETAQKSQRINLQDAETKCLAMADDIYKYLVHHEKKYLLEECFMEGGEPTPKMRRILVDWLVQVHVRFHLTPETLHLTVFILDRMLQKKVTSKADLQLLGISAMFVASKFEEVYLPDIHDYEFITENTYSKKQILAMEQTILNSLNFDLSCP 208
BLAST of Cyclin domain protein vs. Ensembl Fly
Match: CycB3 (gene:FBgn0015625 transcript:FBtr0334578) HSP 1 Score: 95.5153 bits (236), Expect = 2.147e-20 Identity = 77/278 (27.70%), Postives = 131/278 (47.12%), Query Frame = 1 Query: 706 EQFDMKIDENFFEYYPY---MFKYLYEREREIKFNKNYLALN-GFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNLMEAFCNFMFDLIILHPASPGIRSSCKSAAAIFMARFIFYT----EYPSWTKILQHYTFYSVTQLKECVLIYMEMLINIFISTKYTFKAVKEKYSLNVKKAIAKNDKLIN 1515 E FD K ++ F+ Y +F YL RE E +Y+ RT L+DW+++VQ ++ ETL + V ++D++ +I K QL+G A IACK +R P I++F Y+ + Y +V+MER L + + + +P+ F R C ++ L ++ +L ++ A+ S ++AA+FMA + + +WT L +YT Y QL + I + + + T K ++ KYS + +AK L N Sbjct: 289 EDFDRKNWDDPFQVSHYAMDIFNYLKVREAEFPI-ADYMPRQIHLTTWMRTLLVDWMVEVQETFELNHETLYLAVKIVDLYLCREVINKEKLQLLGAAAFFIACKYDERQPPLIEDFLYICDGAYNHDELVRMERETLRVIKYDLGIPLSYRFLRR-YARCAKVPMPTL--TLARYILELSLMDYANISFSDSQMASAALFMALRMHGGPGQLDKQTWTSTLIYYTGY---QLADFAEIVTALNAGLHRKPRATIKTIRNKYSHKIFHEVAKVPLLTN 559
BLAST of Cyclin domain protein vs. Ensembl Fly
Match: CycB3 (gene:FBgn0015625 transcript:FBtr0084728) HSP 1 Score: 95.5153 bits (236), Expect = 2.147e-20 Identity = 77/278 (27.70%), Postives = 131/278 (47.12%), Query Frame = 1 Query: 706 EQFDMKIDENFFEYYPY---MFKYLYEREREIKFNKNYLALN-GFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNLMEAFCNFMFDLIILHPASPGIRSSCKSAAAIFMARFIFYT----EYPSWTKILQHYTFYSVTQLKECVLIYMEMLINIFISTKYTFKAVKEKYSLNVKKAIAKNDKLIN 1515 E FD K ++ F+ Y +F YL RE E +Y+ RT L+DW+++VQ ++ ETL + V ++D++ +I K QL+G A IACK +R P I++F Y+ + Y +V+MER L + + + +P+ F R C ++ L ++ +L ++ A+ S ++AA+FMA + + +WT L +YT Y QL + I + + + T K ++ KYS + +AK L N Sbjct: 289 EDFDRKNWDDPFQVSHYAMDIFNYLKVREAEFPI-ADYMPRQIHLTTWMRTLLVDWMVEVQETFELNHETLYLAVKIVDLYLCREVINKEKLQLLGAAAFFIACKYDERQPPLIEDFLYICDGAYNHDELVRMERETLRVIKYDLGIPLSYRFLRR-YARCAKVPMPTL--TLARYILELSLMDYANISFSDSQMASAALFMALRMHGGPGQLDKQTWTSTLIYYTGY---QLADFAEIVTALNAGLHRKPRATIKTIRNKYSHKIFHEVAKVPLLTN 559
BLAST of Cyclin domain protein vs. Ensembl Fly
Match: CycB (gene:FBgn0000405 transcript:FBtr0071914) HSP 1 Score: 94.3597 bits (233), Expect = 3.571e-20 Identity = 76/297 (25.59%), Postives = 138/297 (46.46%), Query Frame = 1 Query: 682 SKEMSNLSEQFDMKIDENFF---EYYPYMFKYLYEREREIKFNKNYLALNGFEE---SFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITL-IKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNLMEAFCNFMFDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPS--------WTKILQHYTFYSVTQLKECVLIYMEMLINIFISTKYTFKAVKEKYSLNVKKAIAKNDKLINFIED 1527 SK ++ + E D EN EY ++ YLY+ E E +K++LA G +E R L+DW+ +V L + ET Q+ V +ID + + K+++ QLVG+ + IA K + F P I +F ++T+D Y + QME + + ++ ++ P+P HF R A + + M + +L + R S +AA++F++ + + + WT L Y+ YS L+ + ++ + + + KA+ KY + + IA +L + D Sbjct: 204 SKRLAGI-EDIDANDKENLVLVSEYVNDIYDYLYQVELEQPIHKDHLA--GQKEVSHKMRAVLIDWINEVHLQFHLAAETFQLAVAIIDRYLQVVKDTKRTYLQLVGVTALFIATKYEELFPPAIGDFVFITDDTYTARQIRQMELQIFKAIDCNLSRPLPIHFLRRYSKAAGAEDEHHTM---SKYFIELASVDYEMATYRPSEIAAASLFLSLHLLNGNHRAGTGFNDRHWTPTLTFYSRYSAAHLRPITRLIAKLARD---APQAKLKAIYNKYQGSKFQKIALRTELTGALMD 491
BLAST of Cyclin domain protein vs. Ensembl Fly
Match: CycB (gene:FBgn0000405 transcript:FBtr0071913) HSP 1 Score: 94.3597 bits (233), Expect = 4.194e-20 Identity = 76/297 (25.59%), Postives = 138/297 (46.46%), Query Frame = 1 Query: 682 SKEMSNLSEQFDMKIDENFF---EYYPYMFKYLYEREREIKFNKNYLALNGFEE---SFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITL-IKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNLMEAFCNFMFDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPS--------WTKILQHYTFYSVTQLKECVLIYMEMLINIFISTKYTFKAVKEKYSLNVKKAIAKNDKLINFIED 1527 SK ++ + E D EN EY ++ YLY+ E E +K++LA G +E R L+DW+ +V L + ET Q+ V +ID + + K+++ QLVG+ + IA K + F P I +F ++T+D Y + QME + + ++ ++ P+P HF R A + + M + +L + R S +AA++F++ + + + WT L Y+ YS L+ + ++ + + + KA+ KY + + IA +L + D Sbjct: 228 SKRLAGI-EDIDANDKENLVLVSEYVNDIYDYLYQVELEQPIHKDHLA--GQKEVSHKMRAVLIDWINEVHLQFHLAAETFQLAVAIIDRYLQVVKDTKRTYLQLVGVTALFIATKYEELFPPAIGDFVFITDDTYTARQIRQMELQIFKAIDCNLSRPLPIHFLRRYSKAAGAEDEHHTM---SKYFIELASVDYEMATYRPSEIAAASLFLSLHLLNGNHRAGTGFNDRHWTPTLTFYSRYSAAHLRPITRLIAKLARD---APQAKLKAIYNKYQGSKFQKIALRTELTGALMD 515
BLAST of Cyclin domain protein vs. Ensembl Fly
Match: CycB (gene:FBgn0000405 transcript:FBtr0309858) HSP 1 Score: 93.9745 bits (232), Expect = 5.098e-20 Identity = 76/297 (25.59%), Postives = 138/297 (46.46%), Query Frame = 1 Query: 682 SKEMSNLSEQFDMKIDENFF---EYYPYMFKYLYEREREIKFNKNYLALNGFEE---SFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITL-IKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNLMEAFCNFMFDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPS--------WTKILQHYTFYSVTQLKECVLIYMEMLINIFISTKYTFKAVKEKYSLNVKKAIAKNDKLINFIED 1527 SK ++ + E D EN EY ++ YLY+ E E +K++LA G +E R L+DW+ +V L + ET Q+ V +ID + + K+++ QLVG+ + IA K + F P I +F ++T+D Y + QME + + ++ ++ P+P HF R A + + M + +L + R S +AA++F++ + + + WT L Y+ YS L+ + ++ + + + KA+ KY + + IA +L + D Sbjct: 232 SKRLAGI-EDIDANDKENLVLVSEYVNDIYDYLYQVELEQPIHKDHLA--GQKEVSHKMRAVLIDWINEVHLQFHLAAETFQLAVAIIDRYLQVVKDTKRTYLQLVGVTALFIATKYEELFPPAIGDFVFITDDTYTARQIRQMELQIFKAIDCNLSRPLPIHFLRRYSKAAGAEDEHHTM---SKYFIELASVDYEMATYRPSEIAAASLFLSLHLLNGNHRAGTGFNDRHWTPTLTFYSRYSAAHLRPITRLIAKLARD---APQAKLKAIYNKYQGSKFQKIALRTELTGALMD 519
BLAST of Cyclin domain protein vs. Ensembl Zebrafish
Match: ccnb3 (cyclin B3 [Source:ZFIN;Acc:ZDB-GENE-060929-684]) HSP 1 Score: 105.145 bits (261), Expect = 5.708e-24 Identity = 66/224 (29.46%), Postives = 109/224 (48.66%), Query Frame = 1 Query: 742 EYYPYMFKYLYEREREIKFNKNYLALNGFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNLMEAFCNFMFDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEML 1413 EY +F YL RE + + + R L+DWL++VQ ++ ETL + V + D + +++ K+ QL+G MLIA K +R P + +F Y+ +D YK ++ ME +L+ LNF +N+P+P F R CV L F+ +L +L +R+S ++A + +A + + WT+ LQ ++ YS L V ML Sbjct: 141 EYAKEIFDYLKNREEKFVLCDYMVDQPNLNTNMRAILVDWLVEVQENFELNHETLYLAVKVTDHYLAVSQTKREALQLIGSTAMLIASKFEERAPPCVDDFLYICDDAYKRSQLISMEISILQALNFDINIPVPYRFLRR-YAKCVNAGMDTL--TLARFICELSLLEMEFVPVRASLLASACLLIA--LVTKDLGGWTQCLQFHSGYSAEDLAPVVRKLHHML 359
BLAST of Cyclin domain protein vs. Ensembl Zebrafish
Match: ccnb3 (cyclin B3 [Source:ZFIN;Acc:ZDB-GENE-060929-684]) HSP 1 Score: 105.145 bits (261), Expect = 5.708e-24 Identity = 66/224 (29.46%), Postives = 109/224 (48.66%), Query Frame = 1 Query: 742 EYYPYMFKYLYEREREIKFNKNYLALNGFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNLMEAFCNFMFDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEML 1413 EY +F YL RE + + + R L+DWL++VQ ++ ETL + V + D + +++ K+ QL+G MLIA K +R P + +F Y+ +D YK ++ ME +L+ LNF +N+P+P F R CV L F+ +L +L +R+S ++A + +A + + WT+ LQ ++ YS L V ML Sbjct: 141 EYAKEIFDYLKNREEKFVLCDYMVDQPNLNTNMRAILVDWLVEVQENFELNHETLYLAVKVTDHYLAVSQTKREALQLIGSTAMLIASKFEERAPPCVDDFLYICDDAYKRSQLISMEISILQALNFDINIPVPYRFLRR-YAKCVNAGMDTL--TLARFICELSLLEMEFVPVRASLLASACLLIA--LVTKDLGGWTQCLQFHSGYSAEDLAPVVRKLHHML 359
BLAST of Cyclin domain protein vs. Ensembl Zebrafish
Match: ccnb3 (cyclin B3 [Source:ZFIN;Acc:ZDB-GENE-060929-684]) HSP 1 Score: 105.145 bits (261), Expect = 5.708e-24 Identity = 66/224 (29.46%), Postives = 109/224 (48.66%), Query Frame = 1 Query: 742 EYYPYMFKYLYEREREIKFNKNYLALNGFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNLMEAFCNFMFDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEML 1413 EY +F YL RE + + + R L+DWL++VQ ++ ETL + V + D + +++ K+ QL+G MLIA K +R P + +F Y+ +D YK ++ ME +L+ LNF +N+P+P F R CV L F+ +L +L +R+S ++A + +A + + WT+ LQ ++ YS L V ML Sbjct: 141 EYAKEIFDYLKNREEKFVLCDYMVDQPNLNTNMRAILVDWLVEVQENFELNHETLYLAVKVTDHYLAVSQTKREALQLIGSTAMLIASKFEERAPPCVDDFLYICDDAYKRSQLISMEISILQALNFDINIPVPYRFLRR-YAKCVNAGMDTL--TLARFICELSLLEMEFVPVRASLLASACLLIA--LVTKDLGGWTQCLQFHSGYSAEDLAPVVRKLHHML 359
BLAST of Cyclin domain protein vs. Ensembl Zebrafish
Match: ccnb2 (cyclin B2 [Source:ZFIN;Acc:ZDB-GENE-030429-12]) HSP 1 Score: 101.293 bits (251), Expect = 8.328e-23 Identity = 66/257 (25.68%), Postives = 121/257 (47.08%), Query Frame = 1 Query: 706 EQFDMKIDENFFEYYPYMFKYLYEREREIKFNKNYLALNGFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNLMEAFCNFMFDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYME--MLINIFISTKYTFKAVKEKYS 1470 ++ D + + EY ++ YL E + Y+ R L+DWLI+V ++ ETL + V ++D F + + + QLVG+ MLIACK + + P + +F Y+ +D + + +ME +ML LNF + P+P HF R A + + + +L +L S +AAA+ +++ + + W+ QHY+ Y LK + + + +++N +S T V++KY+ Sbjct: 109 DEGDADMPQLCSEYVKDIYFYLRRLEGQQSVRPRYMEGYDINGRMRALLVDWLIQVHSRFQLLQETLYMTVAILDRFLQVQPVTRRKLQLVGVTAMLIACKYEEMYVPMVGDFAYIADDAFTKAQIREMEMLMLSGLNFKLGRPLPLHFLRRASKAGNADAEKH---TLAKYFLELTLLDYDMVHYNPSETAAAALCLSQLVLDGQ--KWSSTQQHYSTYDEAHLKPIMQLIAKNVVMVNEGLSKHLT---VRKKYA 357
BLAST of Cyclin domain protein vs. Ensembl Zebrafish
Match: ccna2 (cyclin A2 [Source:ZFIN;Acc:ZDB-GENE-020418-1]) HSP 1 Score: 94.7449 bits (234), Expect = 2.460e-20 Identity = 72/245 (29.39%), Postives = 121/245 (49.39%), Query Frame = 1 Query: 742 EYYPYMFKYLYEREREIKFNKNYLALN-GFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNLMEAFCNFMFDLIILHPASPGIR--SSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEMLINIFISTKYTFKAVKEKY 1467 +Y + +L E E + K Y+ S R L+DWL++V K+ ETL + V ID F S + + QLVG A ML+A K + + P + EF Y+T+D Y V++ME ++L L+F + P N F + L + + + + E+ F+ +L ++ P ++ S +AAA +A + SW+K L T YS+ L CV ++ ++++ +AV+EKY Sbjct: 173 DYAAEIHTHLREMEVKSKPKAGYMRKQPDITNSMRAILVDWLVEVGEEYKLQNETLYLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLTVLSFDLAAPTINQFLTQYFLH--QPVSSKV-ESLSMFLGELSLID-CDPFLKYLPSQMAAAAFILANHTLASG--SWSKSLVDLTGYSLEDLLPCV---QDLHQTYLAASQHAQQAVREKY 408
BLAST of Cyclin domain protein vs. Ensembl Xenopus
Match: ENSXETT00000018933.1 (cyclin B5 [Source:NCBI gene;Acc:394448]) HSP 1 Score: 103.219 bits (256), Expect = 3.338e-23 Identity = 69/252 (27.38%), Postives = 124/252 (49.21%), Query Frame = 1 Query: 742 EYYPYMFKYLYEREREIKFNKNYLALNGFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNLMEAFCNFM------FDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEMLINIFIST---KYTFKAVKEKYS 1470 +Y ++ YL + E + YL E R L+DWLI+V L ++ ETL + + ++D F I +S QLVG+ + IA K + ++P I +F Y+T++ Y + +ME ++L++LNF + P+P +F R C + + + FM +D++ HP S +AAA+ + + + +W LQ YT YS ++ +++ M+ + + + + F +VK KYS Sbjct: 122 DYVKDIYTYLRQLEVQQAVRPRYLHGMEVNERMRAILVDWLIQVHLKFQLLQETLYMAIAIMDRFLQGQPISRSKLQLVGVTSLFIASKYEEMYYPEISDFVYITDNTYSKAQIREMEMMILKELNFDLGRPLPLNFLRRASKCCSADAGQHTLAKY--FMELTLLDYDMVHFHP-------SAIAAAALCLTQKVL--NIGTWDATLQFYTGYS----QDDLILPMKHMAKVIVQVNQNQTKFLSVKNKYS 358
BLAST of Cyclin domain protein vs. Ensembl Xenopus
Match: ENSXETT00000033191.1 (cyclin B5 [Source:NCBI gene;Acc:394448]) HSP 1 Score: 102.834 bits (255), Expect = 4.095e-23 Identity = 69/252 (27.38%), Postives = 124/252 (49.21%), Query Frame = 1 Query: 742 EYYPYMFKYLYEREREIKFNKNYLALNGFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNLMEAFCNFM------FDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEMLINIFIST---KYTFKAVKEKYS 1470 +Y ++ YL + E + YL E R L+DWLI+V L ++ ETL + + ++D F I +S QLVG+ + IA K + ++P I +F Y+T++ Y + +ME ++L++LNF + P+P +F R C + + + FM +D++ HP S +AAA+ + + + +W LQ YT YS ++ +++ M+ + + + + F +VK KYS Sbjct: 125 DYVKDIYTYLRQLEVQQAVRPRYLHGMEVNERMRAILVDWLIQVHLKFQLLQETLYMAIAIMDRFLQGQPISRSKLQLVGVTSLFIASKYEEMYYPEISDFVYITDNTYSKAQIREMEMMILKELNFDLGRPLPLNFLRRASKCCSADAGQHTLAKY--FMELTLLDYDMVHFHP-------SAIAAAALCLTQKVL--NIGTWDATLQFYTGYS----QDDLILPMKHMAKVIVQVNQNQTKFLSVKNKYS 361
BLAST of Cyclin domain protein vs. Ensembl Xenopus
Match: ENSXETT00000016677.1 (cyclin B3 [Source:NCBI gene;Acc:100494711]) HSP 1 Score: 103.219 bits (256), Expect = 4.544e-23 Identity = 84/283 (29.68%), Postives = 132/283 (46.64%), Query Frame = 1 Query: 676 PKSKEMSNLSEQFDMK-IDENFF--EYYPYMFKYLYEREREIKFN-KNYLALN-GFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDT-NLMEAFCNFM---FDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEMLINIFISTKYTFKAVKEKYSLNVKKAIAK 1497 P+ K + E D +D+ F EY +F Y+ R+RE KF NY+ + + R L+DW+++VQ ++ ETL + V ++D + + T+ K QL+G +LIA K +R P + +F Y+ +D YK VV ME +L+KLNF +N+P+P F R ++T L C +D + S+ K AA + WT LQHY+ Y Q K+ + + + + KAV+ KYS V +AK Sbjct: 133 PEEKVLPPGVEDIDQDSLDDPFSNSEYAMDIFNYM--RDREEKFLLPNYMEMQTDISKDMRAILVDWMVEVQENFELNHETLYLAVKMVDHYLAATVSMKEKLQLIGSTAVLIASKFEERCPPCVDDFMYICDDAYKRDEVVAMEMEILQKLNFDINIPVPYRFLRRFAKCAHATMETLTLARYICELTLQEYDFV--------QESASKMAAGCLLLALKMKG-LGGWTATLQHYSGY---QTKDLLPLVKRLNFLLTHPPNEKLKAVRGKYSHRVFFEVAK 401
BLAST of Cyclin domain protein vs. Ensembl Xenopus
Match: ENSXETT00000033175.1 (cyclin B5 [Source:NCBI gene;Acc:394448]) HSP 1 Score: 102.834 bits (255), Expect = 5.329e-23 Identity = 69/252 (27.38%), Postives = 124/252 (49.21%), Query Frame = 1 Query: 742 EYYPYMFKYLYEREREIKFNKNYLALNGFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNLMEAFCNFM------FDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEMLINIFIST---KYTFKAVKEKYS 1470 +Y ++ YL + E + YL E R L+DWLI+V L ++ ETL + + ++D F I +S QLVG+ + IA K + ++P I +F Y+T++ Y + +ME ++L++LNF + P+P +F R C + + + FM +D++ HP S +AAA+ + + + +W LQ YT YS ++ +++ M+ + + + + F +VK KYS Sbjct: 134 DYVKDIYTYLRQLEVQQAVRPRYLHGMEVNERMRAILVDWLIQVHLKFQLLQETLYMAIAIMDRFLQGQPISRSKLQLVGVTSLFIASKYEEMYYPEISDFVYITDNTYSKAQIREMEMMILKELNFDLGRPLPLNFLRRASKCCSADAGQHTLAKY--FMELTLLDYDMVHFHP-------SAIAAAALCLTQKVL--NIGTWDATLQFYTGYS----QDDLILPMKHMAKVIVQVNQNQTKFLSVKNKYS 370
BLAST of Cyclin domain protein vs. Ensembl Xenopus
Match: ENSXETT00000016648.1 (cyclin B3 [Source:NCBI gene;Acc:100494711]) HSP 1 Score: 101.293 bits (251), Expect = 6.551e-23 Identity = 78/258 (30.23%), Postives = 122/258 (47.29%), Query Frame = 1 Query: 742 EYYPYMFKYLYEREREIKFN-KNYLALN-GFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDT-NLMEAFCNFM---FDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEMLINIFISTKYTFKAVKEKYSLNVKKAIAK 1497 EY +F Y+ R+RE KF NY+ + + R L+DW+++VQ ++ ETL + V ++D + + T+ K QL+G +LIA K +R P + +F Y+ +D YK VV ME +L+KLNF +N+P+P F R ++T L C +D + S+ K AA + WT LQHY+ Y Q K+ + + + + KAV+ KYS V +AK Sbjct: 79 EYAMDIFNYM--RDREEKFLLPNYMEMQTDISKDMRAILVDWMVEVQENFELNHETLYLAVKMVDHYLAATVSMKEKLQLIGSTAVLIASKFEERCPPCVDDFMYICDDAYKRDEVVAMEMEILQKLNFDINIPVPYRFLRRFAKCAHATMETLTLARYICELTLQEYDFV--------QESASKMAAGCLLLALKMKG-LGGWTATLQHYSGY---QTKDLLPLVKRLNFLLTHPPNEKLKAVRGKYSHRVFFEVAK 322
BLAST of Cyclin domain protein vs. Ensembl Mouse
Match: Ccnb2 (cyclin B2 [Source:MGI Symbol;Acc:MGI:88311]) HSP 1 Score: 100.908 bits (250), Expect = 1.525e-22 Identity = 64/247 (25.91%), Postives = 120/247 (48.58%), Query Frame = 1 Query: 742 EYYPYMFKYLYEREREIKFNKNYLALNGFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNLMEAFCNFM----FDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEMLINIFISTKYTFKAVKEKYS 1470 +Y +++YL + E N ++L R L+DWL++V ++ ETL + + ++D F L+ + QLVGI +L+A K + F P I++F Y+T++ Y + +ME ++L++L F + P+P HF R A ++ + + + + +D++ HP+ +SC S + + W Q+YT Y +++ E V+ +M + + F AVK KY+ Sbjct: 133 DYVKDIYQYLRQLEVLQSINPHFLDGRDINGRMRAILVDWLVQVHSKFRLLQETLYMCIAIMDRFLQAQLVCRKKLQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLVDYDMVHYHPSQVAAAASCLSQKVLGQGK---------WNLKQQYYTGYMESEVLE-VMQHMAKNVVKVNDNRTKFIAVKNKYA 369
BLAST of Cyclin domain protein vs. Ensembl Mouse
Match: Ccnb1 (cyclin B1 [Source:MGI Symbol;Acc:MGI:88302]) HSP 1 Score: 100.908 bits (250), Expect = 2.166e-22 Identity = 70/221 (31.67%), Postives = 104/221 (47.06%), Query Frame = 1 Query: 715 DMKIDENFF-EYYPYMFKYLYEREREIKFNKNYLALNGFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGL-LACVEIIDTNLMEAFCNF-MFDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYS 1368 D D N EY ++ YL + E E YL + R L+DWLI+VQ+ ++ ET+ + V +ID F + + K QLVG+ M IA K + + P I +F ++T + Y + QME +L LNF + P+P HF R + V++ L + M D ++H A I +A A +A I + WT LQHY YS Sbjct: 156 DDGADPNLCSEYVKDIYAYLRQLEEEQSVRPKYLQGREVTGNMRAILIDWLIQVQMKFRLLQETMYMTVSIIDRFMQNSCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTNNTYTKHQIRQMEMKILRVLNFSLGRPLPLHFLRRASKVGEVDVEQHTLAKYLMELSMLDYDMVHFAPSQI-----AAGAFCLALKIL--DNGEWTPTLQHYLSYS 369
BLAST of Cyclin domain protein vs. Ensembl Mouse
Match: Ccna2 (cyclin A2 [Source:MGI Symbol;Acc:MGI:108069]) HSP 1 Score: 96.6709 bits (239), Expect = 8.787e-22 Identity = 76/271 (28.04%), Postives = 134/271 (49.45%), Query Frame = 1 Query: 667 TVTPKSKEMSNLSEQFDMKIDENFFEYYPYMFKYLYEREREIKFNKNYLALN-GFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNL-MEAFCNFMFDLIILHPASPGIR--SSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEMLINIFISTKYTFKAVKEKY 1467 T +P + +MS + E + ++E +Y + YL E E + K Y+ S R L+DWL++V K+ ETL + V ID F S + + QLVG A ML+A K + + P + EF Y+T+D Y V++ME ++L+ L F + P N F + L + N +E+ F+ +L ++ A P ++ S + AA +A + + SW + L T Y++ LK C++ + + + ++ ++++EKY Sbjct: 6 TESPHAMDMSIVLEDKPVNVNE-VPDYQEDIHTYLREMEVKCKPKVGYMKRQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYSKKQVLRMEHLVLKVLAFDLAAPTVNQFLTQYFL---HLQPANCKVESLAMFLGELSLID-ADPYLKYLPSLIAGAAFHLALYTVTGQ--SWPESLAQQTGYTLESLKPCLVDLHQTYLK---APQHAQQSIREKY 266
BLAST of Cyclin domain protein vs. Ensembl Mouse
Match: Ccna2 (cyclin A2 [Source:MGI Symbol;Acc:MGI:108069]) HSP 1 Score: 97.8265 bits (242), Expect = 2.309e-21 Identity = 75/269 (27.88%), Postives = 133/269 (49.44%), Query Frame = 1 Query: 673 TPKSKEMSNLSEQFDMKIDENFFEYYPYMFKYLYEREREIKFNKNYLALN-GFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNL-MEAFCNFMFDLIILHPASPGIR--SSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEMLINIFISTKYTFKAVKEKY 1467 +P + +MS + E + ++E +Y + YL E E + K Y+ S R L+DWL++V K+ ETL + V ID F S + + QLVG A ML+A K + + P + EF Y+T+D Y V++ME ++L+ L F + P N F + L + N +E+ F+ +L ++ A P ++ S + AA +A + + SW + L T Y++ LK C++ + + + ++ ++++EKY Sbjct: 145 SPHAMDMSIVLEDKPVNVNE-VPDYQEDIHTYLREMEVKCKPKVGYMKRQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYSKKQVLRMEHLVLKVLAFDLAAPTVNQFLTQYFL---HLQPANCKVESLAMFLGELSLID-ADPYLKYLPSLIAGAAFHLALYTVTGQ--SWPESLAQQTGYTLESLKPCLVDLHQTYLK---APQHAQQSIREKY 403
BLAST of Cyclin domain protein vs. Ensembl Mouse
Match: Ccna1 (cyclin A1 [Source:MGI Symbol;Acc:MGI:108042]) HSP 1 Score: 95.5153 bits (236), Expect = 1.099e-20 Identity = 77/269 (28.62%), Postives = 131/269 (48.70%), Query Frame = 1 Query: 670 VTPKSKEMSNLSEQFDMKIDENFFEYYPYMFKYLYEREREIKFNKNYLALN-GFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNLMEAFCNFMFDLIILHPASPGIR--SSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEMLINIFISTKYTFKAVKEKY 1467 V P + S + F + N EY + +YL E E + +Y+ E R L+DWL++V K+ TETL + V +D F S + + QLVG A +L+A K + + P + EF Y+T+D Y +++ME ++L+ L F + VP N F + L I T E ++ +L +L A P ++ S +AAA +A +I + W + L +T YS+ ++ C+ + ++I + +A++EKY Sbjct: 143 VDPTTHAQSEEATDFGSDVI-NVTEYAEEIHRYLREAEVRHRPKAHYMRKQPDITEGMRAILVDWLVEVGEEYKLRTETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAILLASKYEEIYPPDVDEFVYITDDTYTKRQLLRMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCIRT---ENLAKYVAELSLLE-ADPFLKYLPSLVAAAAYCLANYIVNRHF--WPETLAAFTGYSLNEIVPCLSELHKACLSIPHRPQ---QAIREKY 401
BLAST of Cyclin domain protein vs. UniProt/SwissProt
Match: sp|Q9FMH5|CCA31_ARATH (Putative cyclin-A3-1 OS=Arabidopsis thaliana OX=3702 GN=CYCA3-1 PE=3 SV=1) HSP 1 Score: 120.553 bits (301), Expect = 1.111e-28 Identity = 79/255 (30.98%), Postives = 132/255 (51.76%), Query Frame = 1 Query: 745 YYPYMFKYLYEREREIKFNKNYLA--LNGFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTN--LMEAFCNFMFDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEMLINIFISTK-YTFKAVKEKYSLNVKKAIA 1494 Y +F+YL + E + + +Y+ + R L+DWL++V K+ ++TL + V ID F S+ + K QL+G+ MLIA K + P + +FCY+T++ Y +V+ME +L L F + P N F R E + + ME C+++ +L +L S S +A+A+F+ARFI + W +L+ YT Y LKECV M+ ++++S K +A++EKY + K +A Sbjct: 87 YVTSIFEYLRQLEVKSRPLVDYIEKIQKDVTSNMRGVLVDWLVEVAEEYKLLSDTLYLAVSYIDRFLSLKTVNKQRLQLLGVTSMLIASKYEEITPPNVDDFCYITDNTYTKQEIVKMEADILLALQFELGNPTSNTFLRRFTRVAQEDFEMSHLQMEFLCSYLSELSMLDYQSVKFLPSTVAASAVFLARFIIRPKQHPWNVMLEEYTRYKAGDLKECV----AMIHDLYLSRKCGALEAIREKYKQHKFKCVA 337
BLAST of Cyclin domain protein vs. UniProt/SwissProt
Match: sp|A0MEB5|CCA33_ARATH (Cyclin-A3-3 OS=Arabidopsis thaliana OX=3702 GN=CYCA3-3 PE=2 SV=2) HSP 1 Score: 117.857 bits (294), Expect = 6.668e-28 Identity = 76/248 (30.65%), Postives = 135/248 (54.44%), Query Frame = 1 Query: 745 YYPYMFKYLYEREREIKFNKNYLALNGFEE----SFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDT-NL-MEAFCNFMFDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEMLINIFIS-TKYTFKAVKEKY 1467 Y +++YL E E + K + + +E S R L+DWL++V ++ +ETL + V ID F S+ ++ + + QLVG++ M IA K ++ P++++FCY+T + Y V++ME +L L F + P N F R + E NL +E C ++ +L +L + S +A+A+F+ARFI W+++L+ T Y L+ CV E+++++++S ++ KAV+EKY Sbjct: 56 YVSDIYEYLRELEVKPKLRPLHDYIEKIQEDITPSKRGVLVDWLVEVAEEFELVSETLYLTVSYIDRFLSLKMVNEHWLQLVGVSAMFIASKYEEKRRPKVEDFCYITANTYTKQDVLKMEEDILLALEFELGRPTTNTFLRRFIRVAQEDFKVPNLQLEPLCCYLSELSMLDYSCVKFVPSLLAASAVFLARFIILPNQHPWSQMLEECTKYKAADLQVCV----EIMLDLYLSRSEGASKAVREKY 299
BLAST of Cyclin domain protein vs. UniProt/SwissProt
Match: sp|Q9DG99|CCNB2_ORYJA (G2/mitotic-specific cyclin-B2 OS=Oryzias javanicus OX=123683 GN=ccnb2 PE=2 SV=1) HSP 1 Score: 118.242 bits (295), Expect = 1.026e-27 Identity = 74/268 (27.61%), Postives = 135/268 (50.37%), Query Frame = 1 Query: 742 EYYPYMFKYLYEREREIKFNKNYLALNGFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNLME-AFCNFMFDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEMLINIFISTKYTFKAVKEKYSLNVKKAIAKNDKL--INFIEDLNS 1536 +Y ++KYL+ E + NY+ E R L+DWL++V ++ ETL + V ++D F + + + QLVG+ ML+ACK + + P + +F Y+T+D + +V+ME+++L L F + P+P HF R ++ D ++ + ++ +L +L R S +AAA+ +++ + + W+ QHY+ Y LK + + + ++ + + F AVK+KYS + KL I+ I LNS Sbjct: 118 QYVKDIYKYLHTLEEQQAIRPNYMQGYSVTEHMRALLVDWLVQVHSRFQLLQETLYLTVAILDRFLQVHPVSRRKLQLVGVTAMLVACKYEEMYPPEVGDFAYITDDAFTKFQIVEMEQVILRSLGFQLGRPLPLHFLRRA----SKVADADVEKHTLAKYLLELTLLDYHMVHYRPSEAAAAALCLSQLLL--DGLPWSLEQQHYSTYDEQHLKPIMQLMAKNVVQV-TEGRTKFLAVKKKYS---------SSKLMKISLIPQLNS 369
BLAST of Cyclin domain protein vs. UniProt/SwissProt
Match: sp|Q9C6Y3|CCA11_ARATH (Cyclin-A1-1 OS=Arabidopsis thaliana OX=3702 GN=CYCA1-1 PE=1 SV=1) HSP 1 Score: 118.242 bits (295), Expect = 3.152e-27 Identity = 79/251 (31.47%), Postives = 127/251 (50.60%), Query Frame = 1 Query: 757 MFKYLYEREREIKFNKNYL--ALNGFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNLMEAFC--NFMFDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEMLINIFISTKYTFKAVKEKYSLNVKKAIAK 1497 ++K+L E + + + +Y+ S R L+DWLI+V ++ ETL + V ID + S +I + QL+G+A M+IA K + P+++EFCY+T++ Y V+ ME +L L F + P F R + A + + LM+ C N++ +L +L S +A+AIF+A++I W LQHYT Y +L+ CV + S T AV+EKYS + K +AK Sbjct: 198 IYKHLRASEAKKRPDVDYMERVQKDVNSSMRGILVDWLIEVSEEYRLVPETLYLTVNYIDRYLSGNVISRQKLQLLGVACMMIAAKYEEICAPQVEEFCYITDNTYLKDEVLDMESDVLNYLKFEMTAPTTKCFLRRFVRAAHGVHEAPLMQLECMANYIAELSLLEYTMLSHSPSLVAASAIFLAKYILDPTRRPWNSTLQHYTQYKAMELRGCVKDLQRLCSTAHGS---TLPAVREKYSQHKYKFVAK 445
BLAST of Cyclin domain protein vs. UniProt/SwissProt
Match: sp|Q9C6A9|CCA32_ARATH (Cyclin-A3-2 OS=Arabidopsis thaliana OX=3702 GN=CYCA3-2 PE=2 SV=1) HSP 1 Score: 113.235 bits (282), Expect = 5.072e-26 Identity = 79/248 (31.85%), Postives = 127/248 (51.21%), Query Frame = 1 Query: 751 PYMFK-YLYEREREIKFNKNYL------ALNGFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHR-GLLACVEIIDTNL-MEAFCNFMFDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEMLINIFISTKYTFKAVKEKY 1467 PY+ Y Y R+ E+K + L S R L+DWL++V K+ +ETL + V ID F S+ + K QLVG++ MLIA K + P++ +FCY+T++ + VV+ME +L L F + P N F R +A + +L +E C ++ +L IL + S +A+A+F+ARFI + W ++L+ YT Y L+ CV I ++ ++ +AV+EKY Sbjct: 101 PYVADIYEYLRQLEVKPKQRPLPDYIEKVQKDVTPSMRGVLVDWLVEVAEEYKLGSETLYLTVSHIDRFLSLKTVNKQKLQLVGVSAMLIASKYEEISPPKVDDFCYITDNTFSKQDVVKMEADILLALQFELGRPTINTFMRRFTRVAQDDFKVPHLQLEPLCCYLSELSILDYKTVKFVPSLLAASAVFLARFIIRPKQHPWNQMLEEYTKYKAADLQVCVGIIHDLYLS---RRGGALQAVREKY 345
BLAST of Cyclin domain protein vs. TrEMBL
Match: D2DJT4 (CyclinA-like protein (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 207.608 bits (527), Expect = 9.517e-62 Identity = 97/97 (100.00%), Postives = 97/97 (100.00%), Query Frame = 1 Query: 889 MTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACV 1179 MTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACV Sbjct: 1 MTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACV 97
BLAST of Cyclin domain protein vs. TrEMBL
Match: A0A183AY11 (Cyclin N-terminal domain-containing protein OS=Echinostoma caproni OX=27848 GN=ECPE_LOCUS11846 PE=3 SV=1) HSP 1 Score: 149.828 bits (377), Expect = 7.762e-36 Identity = 77/209 (36.84%), Postives = 121/209 (57.89%), Query Frame = 1 Query: 712 FDMKIDENFFEYYPYMFKYLYEREREIK--FNKNYLALNGFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSI-TLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEII--DTNLMEAFCNFMFDLIILHPASPGIRSSCKSAAAIFMARFIFYTE 1323 DM + F ++ +F+YLY R+ E + +L NG R TL DW+IKVQ Y K+ TETL + V L+D +T + + S YQLVGI + +A K V+RF P CYLTE+ YKP V++ E +L+ L+F V +P+P+HF R +LAC ++ + +E C ++F+L + ++ G+ +S + AAA+ + R + E Sbjct: 136 IDMAQFDEFHMHHERIFRYLYTRDLEATSYYKAEFLRRNGLSADIRATLCDWMIKVQQYLKLRTETLHLAVSLVDRYTWLQDRMNPSDYQLVGITALFVAAKFVERFAPTTTTLCYLTENSYKPKQVLEFELHLLQTLDFDVAIPLPHHFLTRAMLACDDLTYSERAKVELICCYLFELSLTEVSAVGVPASTRCAAAVRLVRQLLQVE 344
BLAST of Cyclin domain protein vs. TrEMBL
Match: A0A4Z2DTV0 (G2/mitotic-specific cyclin-B1 isoform 1 OS=Schistosoma japonicum OX=6182 GN=EWB00_007066 PE=3 SV=1) HSP 1 Score: 152.14 bits (383), Expect = 1.458e-35 Identity = 75/196 (38.27%), Postives = 123/196 (62.76%), Query Frame = 1 Query: 757 MFKYLYEREREIK--FNKNYLALNGFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFT--SITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTN--LMEAFCNFMFDLIILHPASPGIRSSCKSAAAIFMARFIFYTEY 1326 +F+YL+ ++ ++ + +N+L +G ES R+TL DW+IKVQ Y K+ TE+L + V L+D +T ITL S YQL+GI + IA K ++RF P K CYLTE+ Y P V+ E ML+ L+F +N+P+P+HF R ++AC ++ T +E C ++F+L + ++ G+ ++ K AA +++ R + EY Sbjct: 354 IFRYLFTQDLKVTSYYQENFLERHGLTESVRSTLCDWMIKVQQYLKLRTESLHLAVNLVDQYTWRQITLCP-SDYQLLGITAIFIAVKFIERFPPATKTLCYLTENSYSPKQVLDFEMKMLQVLDFCINIPLPHHFLDRAIVACNDLTVTGKAKIELACRYLFELSLTELSAAGVLATVKCAAGVYLTRELIRLEY 548
BLAST of Cyclin domain protein vs. TrEMBL
Match: A0A4E0R5N2 (Putative cyclin OS=Fasciola hepatica OX=6192 GN=D915_007018 PE=3 SV=1) HSP 1 Score: 150.599 bits (379), Expect = 5.446e-35 Identity = 97/300 (32.33%), Postives = 153/300 (51.00%), Query Frame = 1 Query: 712 FDM-KIDENFFEYYPYMFKYLYEREREIK--FNKNYLALNGFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITL-IKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEII--DTNLMEAFCNFMFDLIILHPASPGIRSSCKSAAAIFMARFIFYTE---------------------YPSWT----KILQHYTFYSVTQLKECVLIYMEMLINI---FISTKYTFKAVKEKYSLNVKKAIAKNDKL 1509 DM K+DE F ++ +F+YLY R+ E + +L G E+ R+TL DW+IKVQ Y K+ TETL + + L+D +T + + S YQLVGI + +A K V+RF P CYLTE+ Y+ V+ E +L+ L+F V +P+P+HF R LLAC ++ + +E C ++F+L + ++ G+ +S + AAA+ + R + E + +W +IL H L+ LIY+ L + K F+A K+S +AIA+ D L Sbjct: 350 IDMAKLDE-FHMHHERIFRYLYARDLEATSYYKAEFLKRIGLSENIRSTLCDWMIKVQQYLKLRTETLHLAISLVDRYTWLQCELNPSDYQLVGITALFVAAKFVERFAPTTSTLCYLTENSYRTKQVLDFELHLLQTLDFDVAIPLPHHFLTRALLACDDLTYSERAKVELICCYLFELSLTEASAVGVAASTRCAAAVRLVRQLLQAERERVTSSPNTSALDTDSFELGFDAWNDRMVRILGH---DDSPHLRATALIYVRALRRFQPGAVVFKGKFEAAFHKFSNRGYRAIAQCDTL 645
BLAST of Cyclin domain protein vs. TrEMBL
Match: A0A074ZNV4 (Uncharacterized protein (Fragment) OS=Opisthorchis viverrini OX=6198 GN=T265_13461 PE=3 SV=1) HSP 1 Score: 147.517 bits (371), Expect = 3.230e-34 Identity = 94/283 (33.22%), Postives = 144/283 (50.88%), Query Frame = 1 Query: 748 YPYMFKYLYER--EREIKFNKNYLALNGFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSF----YQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEI--IDTNLMEAFCNFMFDLIILHPASPGIRSSCKSAAAIFMARFIFYTE---------------YPS------WTKILQHYTFYSVT-QLKECVLIYMEMLINI---FISTKYTFKAVKEKYSLNVKKAIAK 1497 + +++YL+ R ER FN +L N E R TL DW+IKVQ Y K+ TETL + V ++D +T +KK+ YQLVGI + +A K V+RF P CYLTE+ YKP V+ E +L KL+F + +P+P+HF R +LAC ++ I+ +E ++F+L + + G +S + AAA+ +AR + E +P W +IL + T +L+ L Y+ L F ST F+A K+S K +A+ Sbjct: 290 HAVIYRYLFTRDMERTSLFNPEFLKQNSLTEDIRATLCDWMIKVQQYLKLRTETLHLAVSIVDQYT---WLKKNMNPIDYQLVGITALFVAAKFVERFAPSSATLCYLTENSYKPRQVLDFEHSLLRKLDFDLTIPLPHHFLTRAVLACSDLTTIEKAKVELISCYLFELSLTETSIVGFSASIRCAAAVRLARHLIDLERIRIQQTRSSSPLLLHPDRQQVEPWPEILIRSVGHGDTPRLRAVCLTYVRALRRFKTGFSSTTEKFEAAFHKFSNRGYKGVAQ 569
BLAST of Cyclin domain protein vs. Ensembl Cavefish
Match: ccnb2 (G2/mitotic-specific cyclin-B2 [Source:NCBI gene;Acc:103043733]) HSP 1 Score: 107.071 bits (266), Expect = 8.616e-25 Identity = 76/263 (28.90%), Postives = 129/263 (49.05%), Query Frame = 1 Query: 706 EQFDMKIDENFFEYYPYMFKYLYEREREIKFNKNYLALNGFE--ESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLAC-VEIIDTNLMEAFCNFM---FDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEMLINIF-ISTKYT-FKAVKEKYS 1470 ++ D +I + EY ++ YL E + Y+ +G+E E R L+DWLI+V ++ ETL + V ++D F + + + QL G+ ML+A K + F P + +F Y+T++ + + +ME I+L +LNF + P+P HF R A + L + F +D++ HP+ G AA + +++ + + W+ +HYT YS LK I M N+ ++ T F AVK+KYS Sbjct: 107 DKGDAEIPQLCSEYVKDIYVYLRSLEAQQSIRPRYM--DGYEINERMRALLVDWLIQVHSRFQLLQETLYMTVAILDRFLQVQPVSRKKLQLAGVTAMLLASKYEEMFVPEVGDFAYITDNAFTKPQIREMEMIILRELNFELGRPLPLHFLRRASKAGNADAEKHTLAKYFLELTLLDYDMVHYHPSEIG-------AAGLCLSQLVIDGQ--KWSPTQEHYTTYSEAHLKP---IMQHMAKNVVKVNEGLTKFMAVKKKYS 355
BLAST of Cyclin domain protein vs. Ensembl Cavefish
Match: ccnb3 (G2/mitotic-specific cyclin-B3-like [Source:NCBI gene;Acc:103043213]) HSP 1 Score: 105.916 bits (263), Expect = 1.901e-24 Identity = 64/227 (28.19%), Postives = 113/227 (49.78%), Query Frame = 1 Query: 742 EYYPYMFKYLYEREREI---KFNKNYLALNGFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNLMEAFCNFMFDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEML 1413 EY +F YL RE + + + L+LN ++ R L+DWL++VQ ++ ETL + V + D + +++ + QL+G ML+ACK +R P + +F Y+ +D YK ++ ME +L+ LNF +N+P+P F R CV L F+ +L ++ +R+S ++A + +A + + WT L+ ++ Y+ L ML Sbjct: 148 EYAKEIFDYLKNREEKFVLKDYMDSQLSLN---QNMRAILVDWLVEVQENFELNHETLYLAVKMTDHYLAVSQASRESLQLIGSTAMLLACKFEERLPPCVDDFLYICDDAYKRSQIITMEGTILQALNFDINIPVPYRFLRR-YAKCVNAGMDTL--TLARFVCELSLMEMQFVPVRASLLASACLLIA--LVTKDLGGWTPCLEFHSGYNTEDLAPVARKLQHML 366
BLAST of Cyclin domain protein vs. Ensembl Cavefish
Match: ccnb3 (G2/mitotic-specific cyclin-B3-like [Source:NCBI gene;Acc:103043213]) HSP 1 Score: 106.301 bits (264), Expect = 2.932e-24 Identity = 70/249 (28.11%), Postives = 121/249 (48.59%), Query Frame = 1 Query: 742 EYYPYMFKYLYEREREI---KFNKNYLALNGFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNLMEAFCNFMFDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEMLINIFISTKYTFKAVKEKYSLNV 1479 EY +F YL RE + + + L+LN ++ R L+DWL++VQ ++ ETL + V + D + +++ + QL+G ML+ACK +R P + +F Y+ +D YK ++ ME +L+ LNF +N+P+P F R CV L F+ +L ++ +R+S ++A + +A + + WT L+ ++ Y+ L ML S T ++ KYS V Sbjct: 168 EYAKEIFDYLKNREEKFVLKDYMDSQLSLN---QNMRAILVDWLVEVQENFELNHETLYLAVKMTDHYLAVSQASRESLQLIGSTAMLLACKFEERLPPCVDDFLYICDDAYKRSQIITMEGTILQALNFDINIPVPYRFLRR-YAKCVNAGMDTL--TLARFVCELSLMEMQFVPVRASLLASACLLIA--LVTKDLGGWTPCLEFHSGYNTEDLAPVARKLQHMLSRTPDSKLAT---IRSKYSHKV 405
BLAST of Cyclin domain protein vs. Ensembl Cavefish
Match: ccnb2 (G2/mitotic-specific cyclin-B2 [Source:NCBI gene;Acc:103043733]) HSP 1 Score: 105.145 bits (261), Expect = 5.708e-24 Identity = 77/263 (29.28%), Postives = 125/263 (47.53%), Query Frame = 1 Query: 706 EQFDMKIDENFFEYYPYMFKYLYEREREIKFNKNYLALNGFE--ESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLAC-VEIIDTNLMEAFCNFM---FDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEMLINIF-ISTKYT-FKAVKEKYS 1470 ++ D +I + EY ++ YL E + Y+ +G+E E R L+DWLI+V ++ ETL + V ++D F + + + QL G+ ML+A K + F P + +F Y+T++ + + +ME I+L +LNF + P+P HF R A + L + F +D++ HP+ G C S I + W+ +HYT YS LK I M N+ ++ T F AVK+KYS Sbjct: 138 DKGDAEIPQLCSEYVKDIYVYLRSLEAQQSIRPRYM--DGYEINERMRALLVDWLIQVHSRFQLLQETLYMTVAILDRFLQVQPVSRKKLQLAGVTAMLLASKYEEMFVPEVGDFAYITDNAFTKPQIREMEMIILRELNFELGRPLPLHFLRRASKAGNADAEKHTLAKYFLELTLLDYDMVHYHPSEIGAAGLCLSQLVI---------DGQKWSPTQEHYTTYSEAHLKP---IMQHMAKNVVKVNEGLTKFMAVKKKYS 386
BLAST of Cyclin domain protein vs. Ensembl Cavefish
Match: ccnb2 (G2/mitotic-specific cyclin-B2 [Source:NCBI gene;Acc:103043733]) HSP 1 Score: 101.293 bits (251), Expect = 1.009e-22 Identity = 65/232 (28.02%), Postives = 114/232 (49.14%), Query Frame = 1 Query: 706 EQFDMKIDENFFEYYPYMFKYLYEREREIKFNKNYLALNGFE--ESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLAC-VEIIDTNLMEAFCNFM---FDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLK 1383 ++ D +I + EY ++ YL E + Y+ +G+E E R L+DWLI+V ++ ETL + V ++D F + + + QL G+ ML+A K + F P + +F Y+T++ + + +ME I+L +LNF + P+P HF R A + L + F +D++ HP+ G AA + +++ + + W+ +HYT YS LK Sbjct: 107 DKGDAEIPQLCSEYVKDIYVYLRSLEAQQSIRPRYM--DGYEINERMRALLVDWLIQVHSRFQLLQETLYMTVAILDRFLQVQPVSRKKLQLAGVTAMLLASKYEEMFVPEVGDFAYITDNAFTKPQIREMEMIILRELNFELGRPLPLHFLRRASKAGNADAEKHTLAKYFLELTLLDYDMVHYHPSEIG-------AAGLCLSQLVIDGQ--KWSPTQEHYTTYSEAHLK 327
BLAST of Cyclin domain protein vs. Ensembl Sea Lamprey
Match: ccnb2 (cyclin B2 [Source:ZFIN;Acc:ZDB-GENE-030429-12]) HSP 1 Score: 98.2117 bits (243), Expect = 2.204e-22 Identity = 60/221 (27.15%), Postives = 107/221 (48.42%), Query Frame = 1 Query: 742 EYYPYMFKYLYEREREIKFNKNYLALNGFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNLMEAFCNFM----FDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECV 1392 EY ++ Y+ E+E NYL R+ L+DWL++VQ+ ++ ETL + V +ID + + QLVG+ M IA K + + P +++F Y+T+ Y + ME+ +L L F + P+P HF R A D + + + + ++++ HP S +AAA+++++ + + W LQ+YT Y+ +L V Sbjct: 134 EYVKDIYVYMKTLEKEQSVQANYLEGKKINGRMRSILVDWLVQVQMKFRLLQETLYLTVAIIDRYLQVVPFSLVNLQLVGVTAMFIAAKYEEMYSPEMEDFVYITDHAYTKAEIRAMEQAILLGLQFNLGRPLPLHFLRRASKAGSVDADKHTLAKYLMELSLVDYNMVHFHP-------SQIAAAALYLSQKLM--DDSKWNMDLQYYTTYTEEELMPVV 345
BLAST of Cyclin domain protein vs. Ensembl Sea Lamprey
Match: ccna1 (cyclin A1 [Source:ZFIN;Acc:ZDB-GENE-040311-2]) HSP 1 Score: 73.9442 bits (180), Expect = 6.336e-15 Identity = 44/133 (33.08%), Postives = 70/133 (52.63%), Query Frame = 1 Query: 757 MFKYLYEREREIKFNKNYLALN-GFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHF 1152 +++YL + E K Y+ S R+ L+DWL++V K+ +ETL + V ID F S + + QLVG A M +A K + + P + EF ++T+D Y V++ME ++L L+F V P F Sbjct: 31 IYQYLQKAELRCKPKAGYMRKQPDITTSMRSILVDWLVEVVEEYKLHSETLYLAVNYIDRFLSSMSVLRGKLQLVGTAAMYLAAKFEEIYPPEVSEFVFITDDTYTKQQVLRMEHLILRVLSFEVASPTIMQF 163
BLAST of Cyclin domain protein vs. Ensembl Sea Lamprey
Match: ccne1 (cyclin E1 [Source:NCBI gene;Acc:30188]) HSP 1 Score: 57.3806 bits (137), Expect = 2.874e-9 Identity = 37/115 (32.17%), Postives = 59/115 (51.30%), Query Frame = 1 Query: 781 EREIKFNKNYLALNGFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSI-TLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNF 1122 ER+ F + AL R L+DWL++V ++ ETL + + D F + T + KS QL+GI + IA K + + P++ EF Y+T+ +V ME ML+ L + Sbjct: 53 ERDRHFLDRHPALTA---RMRAVLLDWLMQVCEVYRLHRETLYLALDYFDRFLATQTDVCKSQLQLIGITALFIAAKTEEIYPPKLTEFAYVTDGACTEEDIVVMELNMLQSLKW 164
BLAST of Cyclin domain protein vs. Ensembl Yeast
Match: CLB4 (B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the G2/M transition; may be involved in DNA replication and spindle assembly; accumulates during S phase and G2, then targeted for ubiquitin-mediated degradation; CLB4 has a paralog, CLB3, that arose from the whole genome duplication [Source:SGD;Acc:S000004200]) HSP 1 Score: 82.8037 bits (203), Expect = 2.489e-17 Identity = 59/218 (27.06%), Postives = 109/218 (50.00%), Query Frame = 1 Query: 742 EYYPYMFKYLYEREREIKFNKN-YLALNGFEES--FRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNLMEAFCNFMFDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQH--YTFYSVTQL 1380 EY +F YL RE E+K+ N Y N E + FR T++DWL+++ ++ ETL + + ++D F S + + +QLVG++ + IA K + P + + Y+ E+ Y +++ E+ M++ L F + P P F R ++ + D ++ + I+ P S +A A F++R I + W+ L+H Y+ Y+ +Q+ Sbjct: 206 EYASDIFYYL--RELEVKYRPNPYYMQNQVELTWPFRRTMIDWLVQLHFRFQLLPETLYLTINIVDRFLSKKTVTLNRFQLVGVSALFIAAKFEEINCPTLDDLVYMLENTYTRDDIIRAEQYMIDTLEFEIGWPGPMPFLRR--ISKADDYDFE-PRTLAKYLLETTIVEPKLVAAAPSWLAAGAYFLSRTILGSN--DWS--LKHVFYSGYTSSQI 414
BLAST of Cyclin domain protein vs. Ensembl Yeast
Match: CLB3 (B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the G2/M transition; may be involved in DNA replication and spindle assembly; accumulates during S phase and G2, then targeted for ubiquitin-mediated degradation; relative distribution to the nucleus increases upon DNA replication stress; CLB3 has a paralog, CLB4, that arose from the whole genome duplication [Source:SGD;Acc:S000002314]) HSP 1 Score: 81.6481 bits (200), Expect = 4.221e-17 Identity = 59/218 (27.06%), Postives = 105/218 (48.17%), Query Frame = 1 Query: 757 MFKYLYEREREIKFNKNYLALNG-FEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNLMEAFCNFMFDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYME 1407 +F+Y+ + E K N Y+ SFR+TL+DW+++V ++ ETL + + +ID + ++ + +QLVG A + IA K + P IK+F Y++E+CY ++ ER +L L F + P P F R A DT + ++ + I+ + S +A A F+++ I W+ +Y+ Y+ Q+ I +E Sbjct: 172 IFEYMRKLEDLYKPNPYYMDKQPELRWSFRSTLIDWIVQVHEKFQLLPETLYLCINIIDRYLCKEVVPVNKFQLVGAASLFIAAKYEEINCPTIKDFVYMSENCYSRNDLLDAERTILNGLEFELGWPGPMSFLRRISKADDYEHDTRTL---AKYLLESTIMDHRLVSAQPSWLAAGAYFLSKIILGQN--QWSLAHVYYSNYTQEQILPLATIILE 384
BLAST of Cyclin domain protein vs. Ensembl Yeast
Match: CLB6 (B-type cyclin involved in DNA replication during S phase; activates Cdc28p to promote initiation of DNA synthesis; functions in formation of mitotic spindles along with Clb3p and Clb4p; most abundant during late G1; CLB6 has a paralog, CLB5, that arose from the whole genome duplication [Source:SGD;Acc:S000003341]) HSP 1 Score: 74.7146 bits (182), Expect = 6.119e-15 Identity = 63/227 (27.75%), Postives = 105/227 (46.26%), Query Frame = 1 Query: 718 MKIDENFF--EYYPYMFKYLYEREREIKFNKNYLALNG----FEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNLMEAF-------CNFMFDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYT 1359 +++D+ F EY +F +LYE+E ++ NYL + S R L+DWL++V ETL + + L+D F S ++K + QL+ I + IACK + P+I F Y+T+ + + E +L L + +++P P +F R A I+T M F CN L + S +A ++++AR I E W + HY+ Sbjct: 109 IEMDDPFMVAEYTDSIFSHLYEKEIQMLPTHNYLMDTQSPYHLKSSMRALLIDWLVEVHEKFHCLPETLFLAINLLDRFLSQNVVKLNKLQLLCITCLFIACKFEEVKLPKITNFAYVTDGAATVEGIRKAELFVLSSLGYNISLPNPLNFIRRISKADNYCIETRNMAKFIMEYSICCNKFIHL----------KPSYLAAMSMYIARKI-KNENSKWDETFIHYS 324
BLAST of Cyclin domain protein vs. Ensembl Yeast
Match: CLB5 (B-type cyclin involved in DNA replication during S phase; activates Cdc28p to promote initiation of DNA synthesis; functions in formation of mitotic spindles along with Clb3p and Clb4p; most abundant during late G1 phase; CLB5 has a paralog, CLB6, that arose from the whole genome duplication [Source:SGD;Acc:S000006324]) HSP 1 Score: 74.3294 bits (181), Expect = 1.057e-14 Identity = 62/217 (28.57%), Postives = 98/217 (45.16%), Query Frame = 1 Query: 742 EYYPYMFKYLYEREREIKFNKNYLALNG----FEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLA-CVEIIDTNLME-----AFCNFMFDLIILHPASPGIRSSCKSAAAIFMA-RFIFYTEYPSWTKILQHYT 1359 EY +F +LY RE E + NYL S RT L+DWL++V + ETL + + L+D F + + + QL+ + + IA K + P++ E+ Y+T+ + E ML L F + P P +F R A + ++ N+ + A+C F I L P S SA A+++A R + W LQHY+ Sbjct: 161 EYSAEIFAFLYRRELETLPSHNYLLDKTSKYYLRPSMRTILVDWLVEVHEKFQCYPETLFLSINLMDRFLAKNKVTMNKLQLLAVTSLFIAAKFEEVNLPKLAEYAYITDGAASKNDIKNAEMFMLTSLEFNIGWPNPLNFLRRISKADDYDPVNRNIGKFILEYAYCCHQF--IHLPP-------STVSAMAMYIARRMTNRNKNELWNGTLQHYS 368
BLAST of Cyclin domain protein vs. Ensembl Yeast
Match: CLB2 (B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome; CLB2 has a paralog, CLB1, that arose from the whole genome duplication [Source:SGD;Acc:S000006323]) HSP 1 Score: 72.7886 bits (177), Expect = 3.841e-14 Identity = 59/234 (25.21%), Postives = 109/234 (46.58%), Query Frame = 1 Query: 742 EYYPYMFKYLYEREREIKFNKNYLALNGFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNLMEAFCNFMFDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYT-FYSVTQLKECVLIYMEMLINIFISTKY 1440 EY +F+YL++ E K L + R L++WL+K+ + ETL + + ++D F L++ QLVG + + IA K + + P IK F T+ + + E+ +L+ L F +N P P +F R ++ + D F+ ++ ++ GI S +AAA+FM+R + W L HY+ Y+ +L + M+ L++ + ++ Sbjct: 228 EYVNDIFEYLHQLEVITLPKKEDLYQHRNIHQNRDILVNWLVKIHNKFGLLPETLYLAINIMDRFLGKELVQLDKLQLVGTSCLFIASKYEEVYSPSIKHFASETDGACTEDEIKEGEKFILKTLKFNLNYPNPMNFLRR--ISKADDYDIQ-SRTLAKFLLEISLVDFRFIGILPSLCAAAAMFMSRKMLGK--GKWDGNLIHYSGGYTKEELAPVCHMIMDYLVSPIVHDEF 456
BLAST of Cyclin domain protein vs. Ensembl Nematostella
Match: EDO34387 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SPG5]) HSP 1 Score: 102.449 bits (254), Expect = 3.594e-24 Identity = 68/244 (27.87%), Postives = 119/244 (48.77%), Query Frame = 1 Query: 742 EYYPYMFKYLYEREREIKFNKNYLA-LNGFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNLMEAFCNFMFDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEMLINIFISTKYTFKAVKEKYS 1470 EY + ++L E + Y+ E R L+DWL++V L ++ ETL + + +ID F ++ + K QLVG+ ML+A K + F P I +F Y+T+ Y + QME ++ KL+F + P+ HF R A + + M ++ +L ++ S S +AA++ +A + + WT L+HY+ YS +L C+ ++++ S + KAV KY+ Sbjct: 34 EYAKEIMRFLRAMEEHYSVSPTYMNNQQEVNEKMRAILLDWLVQVHLKFRLLQETLYITMSIIDRFLAVHQVSKRELQLVGVGAMLLASKYEEMFAPEIGDFVYITDHAYTKKQIRQMESLIFRKLDFSLGKPLCLHFLRRNSKAGAVGAEEHTM---AKYLMELTLIDYQSIKFLPSEIAAASLSLAMRVM-GKGSEWTPTLEHYSGYSEKKLSTCMQRLAQLVLGARDSKQ---KAVYNKYA 270
BLAST of Cyclin domain protein vs. Ensembl Nematostella
Match: EDO39942 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S8H6]) HSP 1 Score: 95.5153 bits (236), Expect = 2.078e-22 Identity = 73/237 (30.80%), Postives = 112/237 (47.26%), Query Frame = 1 Query: 835 SFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNLMEAFCNFMFDLIILH----PASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEMLINIFISTKYTFKAVKEKYSLNVKKAIAKNDKLINFIEDLN 1533 S R L+DWL++VQ ++ ETL +GV ++D + + +++ QLVG + IACK+ +R P + +F Y+ +D Y+ V ME+ +L L F +N+PIP F R A V D + F+ + + H P ++ A+ M WT + HYT YSV QL CV+ EM+ K V+ KYS V +A LI ++ LN Sbjct: 10 SMRAILVDWLVEVQESFELYHETLYLGVRVLDNYLMRSYVERENLQLVGAVSLYIACKVEERHPPCLDDFLYICDDAYQQKAFVAMEKKILNSLEFNINMPIPYRFLRR--FAKVASADVKTL-TLSRFILETTLHHYKFIVHKPSFLAAACLRLALRMKGC------DDWTPTVVHYTGYSVAQLDGCVIELNEMISE---PPKQNLMTVRNKYSHKVFHEVA----LIPPLDSLN 230
BLAST of Cyclin domain protein vs. Ensembl Nematostella
Match: EDO37884 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEI5]) HSP 1 Score: 95.5153 bits (236), Expect = 8.440e-22 Identity = 68/227 (29.96%), Postives = 114/227 (50.22%), Query Frame = 1 Query: 742 EYYPYMFKYLYEREREIKFNKNYLALN-GFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNL-------MEAFCNFMFDLIILHPASPGIR--SSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECV 1392 EY +FKYL + E + Y+ S R L+DWL++V K+ +TL + V ID F S + + QLVG A ML+A K + + P + EF Y+T+D Y V++ME+++L+ L F ++VP +F R + A TN+ +EA ++ ++ +L + P ++ S +A+AI ++ Y W L HYT + + L+ C+ Sbjct: 40 EYASDIFKYLKQAELNNRAKPGYMRKQPDINNSMRAILVDWLVEVAEEYKLLPQTLYLTVNYIDRFLSAMSVLRGKLQLVGTACMLLASKFEEIYPPEVSEFVYITDDTYTAKQVLKMEQLVLKVLTFDLSVPTILNFLERFIKA------TNVPESMAPKVEALARYLCEISLLD-SEPFLKYLPSTIAASAIVLSLHTLGLSY--WNNTLSHYTGFELHDLQTCI 257
BLAST of Cyclin domain protein vs. Ensembl Nematostella
Match: EDO32608 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SUL2]) HSP 1 Score: 73.1738 bits (178), Expect = 5.091e-15 Identity = 44/155 (28.39%), Postives = 77/155 (49.68%), Query Frame = 1 Query: 841 RTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNLMEAFCNFMFDLIILHPASPGIRSSCKSAAAIFMAR 1305 R L+DWLI+V L+ + L + V L+D + S+ + + +QL+G+A +L+ACK RF P +E + + + ++ ME +L L F + P+P F A ++T ++ F+ + +L + S +A A FMAR Sbjct: 46 RAVLIDWLIEVHLFYNFPQDCLYLIVALVDRYMSLRTVPVAHFQLLGMACLLVACKYEDRFVPTREELVAMADQAFDQSELMHMETRLLTCLEFDLAQPLPTFFLRPIARASAIDLETYVVS---KFIMEAAMLDAIMVTFKPSIIAATAFFMAR 197
BLAST of Cyclin domain protein vs. Ensembl Nematostella
Match: EDO33920 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SQU4]) HSP 1 Score: 69.3218 bits (168), Expect = 3.562e-13 Identity = 40/126 (31.75%), Postives = 70/126 (55.56%), Query Frame = 1 Query: 757 MFKYLYEREREIKFNKNYLALNG---FEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITL-IKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNF 1122 ++ Y+ E++R K+ K++L L + R L+DWLI+V ++ ET + V +D + S+ I K QLVG + IA K+ + + P++ EF Y+T+ K ++Q E +ML+ LN+ Sbjct: 14 LWSYMLEKDR--KYTKDHLYLRQHPHLQPRMRAILLDWLIEVCEVYRLHRETYFLAVDFVDRYLSVKKDIPKQRLQLVGTTALFIAAKLEEIYPPKLSEFAYVTDGACKEDEILQQELLMLQDLNW 137
BLAST of Cyclin domain protein vs. Ensembl Medaka
Match: ccnb2 (cyclin B2 [Source:NCBI gene;Acc:100049213]) HSP 1 Score: 114.775 bits (286), Expect = 1.929e-27 Identity = 87/338 (25.74%), Postives = 156/338 (46.15%), Query Frame = 1 Query: 550 KPTRFTFSHNRTSFKHGSKITDLSSEDNLVMICQ-----LLLIRTVTPKSKEMSNLSEQFDMKIDENFFEYYPYMFKYLYEREREIKFNKNYLALNGFE--ESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNLMEAFCNFMFDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEMLINIFISTKYTFKAVKEKYSLNVKKAIAKNDKL--INFIEDLNS 1536 KPT+ S +T + + S +CQ LL ++ V + + L Q+ I +KYL+ E + NY+ G+E E R L+DWL++V ++ ETL + V ++D F + + + QLVG+ ML+ACK + + P + +F Y+T++ + +V+ME+++L L+F + P+P HF R ++ + ++ +L +L R S +AAA+ +++ + + W+ Q Y+ Y LK ++ +M + + + F AVK+KYS + KL I+ I LNS Sbjct: 65 KPTQLVASMIQTGAAASAPVLAKPSVKEEQELCQAFSEVLLAVQDVDEQDADQPQLCSQYVKDI-----------YKYLHILEEQQPVRANYM--QGYEVTERMRALLVDWLVQVHSRFQLLQETLYLTVAILDRFLQVHPVSRRKLQLVGVTAMLVACKYEEMYAPEVGDFAYITDNAFTKSQIVEMEQVILRSLSFQLGRPLPLHFLRRATKVAGADVEKH---TLAKYLMELTLLDYHMVHYRPSEVAAAALCLSQLLL--DGLPWSLTQQQYSTYEEQHLKP-IMQHMAKNVVLVNEGRTKFLAVKKKYS---------SSKLMKISLIPQLNS 374
BLAST of Cyclin domain protein vs. Ensembl Medaka
Match: ccnb3 (cyclin B3 [Source:NCBI gene;Acc:101158560]) HSP 1 Score: 106.686 bits (265), Expect = 1.970e-24 Identity = 75/250 (30.00%), Postives = 117/250 (46.80%), Query Frame = 1 Query: 742 EYYPYMFKYLYEREREIKFNKNYLALNGFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDT-NLMEAFCNFMF---DLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEMLINIFISTKYTFKAVKEKYSLNV 1479 EY +F YL ERE + + L R L+DWL++VQ ++ ETL + V + D + S I + QLVG MLIA K +R P + +F Y+ +D YK ++ ME +L+ L+F +N+PIP F R ++T L +C DL+ R S ++A + MA + + SW+ ILQ F+S Q E + ++ + + +AV+ KYS V Sbjct: 167 EYAKDIFDYLKEREEKFVLSNYMLTHTSLNPEMRAILVDWLVEVQENFELYHETLYLAVKMTDHYLSKASIHREMLQLVGSTAMLIASKFEERSPPCVDDFLYICDDAYKREELISMEASILQTLSFDINIPIPYRFLRRYAKCVSASMETLTLARYYCEMSLMEMDLV-------SERGSLLASACLLMA--LITKDLGSWSPILQ---FHSGYQASEVAPVVRKLHLMLQGPADDKLRAVRNKYSHKV 404
BLAST of Cyclin domain protein vs. Ensembl Medaka
Match: ccnb3 (cyclin B3 [Source:NCBI gene;Acc:101158560]) HSP 1 Score: 105.916 bits (263), Expect = 2.213e-24 Identity = 75/250 (30.00%), Postives = 117/250 (46.80%), Query Frame = 1 Query: 742 EYYPYMFKYLYEREREIKFNKNYLALNGFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDT-NLMEAFCNFMF---DLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEMLINIFISTKYTFKAVKEKYSLNV 1479 EY +F YL ERE + + L R L+DWL++VQ ++ ETL + V + D + S I + QLVG MLIA K +R P + +F Y+ +D YK ++ ME +L+ L+F +N+PIP F R ++T L +C DL+ R S ++A + MA + + SW+ ILQ F+S Q E + ++ + + +AV+ KYS V Sbjct: 123 EYAKDIFDYLKEREEKFVLSNYMLTHTSLNPEMRAILVDWLVEVQENFELYHETLYLAVKMTDHYLSKASIHREMLQLVGSTAMLIASKFEERSPPCVDDFLYICDDAYKREELISMEASILQTLSFDINIPIPYRFLRRYAKCVSASMETLTLARYYCEMSLMEMDLV-------SERGSLLASACLLMA--LITKDLGSWSPILQ---FHSGYQASEVAPVVRKLHLMLQGPADDKLRAVRNKYSHKV 360
BLAST of Cyclin domain protein vs. Ensembl Medaka
Match: ccna2 (cyclin A2 [Source:NCBI gene;Acc:101166612]) HSP 1 Score: 100.908 bits (250), Expect = 1.959e-22 Identity = 82/265 (30.94%), Postives = 125/265 (47.17%), Query Frame = 1 Query: 697 NLSEQFDMKIDEN-FFEYYPYMFKYLYEREREIKFNKNYLALN-GFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPN-----HFCHRGLLACVEIIDTNLMEAFCNFMFDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEMLINIFIS-TKYTFKAVKEKY 1467 +L E D +++ N EY + YL E E + + Y+ S R L+DWL++V K+ ETL + V ID F S + + QLVG A ML+A K + + P + EF Y+T+D Y V++ME ++L+ L+F + P N +FCH G+ VE + L E LI P + S +AA I + SW K L T Y + L C+ E L +F+S ++ ++V+EKY Sbjct: 158 SLVEVDDKQVNVNEVPEYAAEIHLYLREMEVKTRPKAGYMKKQPDITNSMRAILVDWLVEVGEEYKLHNETLYLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLAAKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLSFDLAAPTINQFLTQYFCHHGVNKQVESLAMYLGE------LSLIDSDPFLKYLPSQTAAAAYILANHAVTGG---SWPKSLAEMTGYMLVDLMPCI----EDLHKMFLSAAQHAQQSVREKY 409
BLAST of Cyclin domain protein vs. Ensembl Medaka
Match: ccnb1 (cyclin B1 [Source:NCBI gene;Acc:100049212]) HSP 1 Score: 90.1225 bits (222), Expect = 3.275e-19 Identity = 69/267 (25.84%), Postives = 122/267 (45.69%), Query Frame = 1 Query: 742 EYYPYMFKYLYEREREIKFNKNYLALNGFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNLMEAFCNFMFDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEMLINIFISTKYTFKAVKEKYSLNVKKAIAKNDKL-INFIEDLNSK 1539 EY ++KYL + E E NYL + R L+DWL++V L ++ ET+ + V +ID F + K QLVG+ M +A K + + P I +F Y+T+ Y + ME +L L F + P+P F R E+ T ++ +L ++ S ++AA+ + + + W LQHY Y+ L + + ++ + + + A+K KYS + + IA +L + ++DL ++ Sbjct: 103 EYVKDIYKYLRQLEMEQSVKPNYLEGQEITGNMRAILIDWLVQVGLKFRLLQETMYMTVGIIDRFLQDHPVPKKQLQLVGVTAMFLASKYEEMYPPEISDFAYVTDRAYTTAQIRDMEMTILRVLKFQLGRPLPLQFLRRA-SKIYEV--TAEQHTLAKYLLELSMVDYDMAHFPPSLVASAALALTLKVL--DAGEWDVTLQHYMEYTAETLTPVMAHIAKNVVKVN-NGQTKHMAIKGKYSTSKQMRIATISQLKSSVVKDLATQ 363
BLAST of Cyclin domain protein vs. Planmine SMEST
Match: SMESG000048937.1 (SMESG000048937.1) HSP 1 Score: 926.776 bits (2394), Expect = 0.000e+0 Identity = 482/482 (100.00%), Postives = 482/482 (100.00%), Query Frame = 1 Query: 121 MPIYTSSQRKSLIPDAYKKGSSLQKFYKTTPYYERRKSSPYIQEKNVTENKLEFASDSLLQQRKSKISLSKVKRMKCFIRRYXXXXXXXXXXXXXETRKSNLSSDRFSQLRHIWXXXXXXXXXXXXXXXXQSERKHVSNTPTSKPTRFTFSHNRTSFKHGSKITDLSSEDNLVMICQLLLIRTVTPKSKEMSNLSEQFDMKIDENFFEYYPYMFKYLYEREREIKFNKNYLALNGFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNLMEAFCNFMFDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEMLINIFISTKYTFKAVKEKYSLNVKKAIAKNDKLINFIEDLNSKQRIINYFEK 1566 MPIYTSSQRKSLIPDAYKKGSSLQKFYKTTPYYERRKSSPYIQEKNVTENKLEFASDSLLQQRKSKISLSKVKRMKCFIRRYSKSTKLSSSNSNNETRKSNLSSDRFSQLRHIWSKERSKPKPKPIIPRRQSERKHVSNTPTSKPTRFTFSHNRTSFKHGSKITDLSSEDNLVMICQLLLIRTVTPKSKEMSNLSEQFDMKIDENFFEYYPYMFKYLYEREREIKFNKNYLALNGFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNLMEAFCNFMFDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEMLINIFISTKYTFKAVKEKYSLNVKKAIAKNDKLINFIEDLNSKQRIINYFEK Sbjct: 1 MPIYTSSQRKSLIPDAYKKGSSLQKFYKTTPYYERRKSSPYIQEKNVTENKLEFASDSLLQQRKSKISLSKVKRMKCFIRRYSKSTKLSSSNSNNETRKSNLSSDRFSQLRHIWSKERSKPKPKPIIPRRQSERKHVSNTPTSKPTRFTFSHNRTSFKHGSKITDLSSEDNLVMICQLLLIRTVTPKSKEMSNLSEQFDMKIDENFFEYYPYMFKYLYEREREIKFNKNYLALNGFEESFRTTLMDWLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKPGHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNLMEAFCNFMFDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYPSWTKILQHYTFYSVTQLKECVLIYMEMLINIFISTKYTFKAVKEKYSLNVKKAIAKNDKLINFIEDLNSKQRIINYFEK 482
BLAST of Cyclin domain protein vs. Planmine SMEST
Match: SMESG000077303.1 (SMESG000077303.1) HSP 1 Score: 48.9062 bits (115), Expect = 3.213e-6 Identity = 48/194 (24.74%), Postives = 85/194 (43.81%), Query Frame = 1 Query: 859 WLIKVQLYSKMTTETLQVGVVLIDMFTSITLIKKSFYQLVGIAGMLIACKIVQRFHPRIKEFCYLTEDCYKP--GHVVQMERIMLEKLNFFVNVPIPNHFCHRGLLACVEIIDTNLMEAFCNFMFDLIILHPASPGIRSSCKSAAAIFMARFIFYTEYP----SWTKILQHYTFYSVTQLKECVLIYMEMLINI 1422 W I + ++++ +++ + + L D + I +KK + +GI + IA KI F +K T Y G ME +L +L+F VN+P P F R V +T A F+ DL + G+ S +A++ F + P SW +L+ Y+ + + + + + MLIN+ Sbjct: 2 WFITIANKTEISNDSIHLAIALFDYYYQI--VKKDYNLYIGIIMLWIASKIEDSFPISLKNIINHTHLNYDEIHGQCKTMELDILNELDFDVNLPTPIQFL-RHFTKIVHTTETCHQTA--KFIIDLTLTDNKFIGLNYSLMAASS-FCIALDLIKKVPEMGDSWNTLLKRYSSFDKSNILPVMKEMVAMLINL 189 The following BLAST results are available for this feature:
BLAST of Cyclin domain protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Cyclin domain protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Cyclin domain protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Cyclin domain protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Cyclin domain protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Cyclin domain protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Cyclin domain protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Cyclin domain protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Cyclin domain protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Cyclin domain protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 3
BLAST of Cyclin domain protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Cyclin domain protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Cyclin domain protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Cyclin domain protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 2
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30021342 ID=SMED30021342|Name=Cyclin domain protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1655bpback to top protein sequence of SMED30021342-orf-1 >SMED30021342-orf-1 ID=SMED30021342-orf-1|Name=SMED30021342-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=483bp MPIYTSSQRKSLIPDAYKKGSSLQKFYKTTPYYERRKSSPYIQEKNVTENback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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