Cytochrome c

Overview


Name	Cytochrome c
Smed ID	SMED30021332
Length (bp)	540

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Cytochrome c (SMED30021332) t-SNE clustered cells

Violin plots show distribution of expression levels for Cytochrome c (SMED30021332) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Cytochrome c (SMED30021332) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Cytochrome c (SMED30021332) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30021332

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
intestinal phagocyte	SMED30021332	h1SMcG0004011	Contig1287	GPL15192	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30021332	h1SMcG0020068	Contig1287	GPL15192	PMID:23079596 Forsthoefel et al., 2012
pharynx	SMED30021332	h1SMcG0004011	dd_Smed_v4_464_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30021332	h1SMcG0004011	dd_Smed_v4_464_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30021332	h1SMcG0004011	dd_Smed_v4_464_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
intestinal phagocyte	SMED30021332	h1SMcG0004011	dd_Smed_v6_464_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of Cytochrome c vs. Ensembl Human
Match: CYCS (cytochrome c, somatic [Source:HGNC Symbol;Acc:HGNC:19986])

HSP 1 Score: 176.022 bits (445), Expect = 3.923e-57
Identity = 79/102 (77.45%), Postives = 92/102 (90.20%), Query Frame = 2

Query:  134 GNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLKDAT 439
            G+V KGK +F+ +CSQCHTVEKGG HKTGPNL+GLFGRKTGQAPGY YTAANKNKGI+WG DTL EYL +P+KYIPGTKM+F G+KK++ERAD+IAYLK AT
Sbjct:    2 GDVEKGKKIFIMKCSQCHTVEKGGKHKTGPNLHGLFGRKTGQAPGYSYTAANKNKGIIWGEDTLMEYLENPKKYIPGTKMIFVGIKKKEERADLIAYLKKAT 103

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Query:  134 GNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLKDAT 439
            G+V KGK +F+ +CSQCHTVEKGG HKTGPNL+GLFGRKTGQAPGY YTAANKNKGI+WG DTL EYL +P+KYIPGTKM+F G+KK++ERAD+IAYLK AT
Sbjct:    2 GDVEKGKKIFIMKCSQCHTVEKGGKHKTGPNLHGLFGRKTGQAPGYSYTAANKNKGIIWGEDTLMEYLENPKKYIPGTKMIFVGIKKKEERADLIAYLKKAT 103

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Query:  134 GNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLKDAT 439
            G+V KGK +F+ +CSQCHTVEKGG HKTGPNL+GLFGRKTGQAPGY YTAANKNKGI+WG DTL EYL +P+KYIPGTKM+F G+KK++ERAD+IAYLK AT
Sbjct:    2 GDVEKGKKIFIMKCSQCHTVEKGGKHKTGPNLHGLFGRKTGQAPGYSYTAANKNKGIIWGEDTLMEYLENPKKYIPGTKMIFVGIKKKEERADLIAYLKKAT 103

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BLAST of Cytochrome c vs. Ensembl Human
Match: CYCS (cytochrome c, somatic [Source:HGNC Symbol;Acc:HGNC:19986])

HSP 1 Score: 172.17 bits (435), Expect = 1.281e-55
Identity = 77/99 (77.78%), Postives = 90/99 (90.91%), Query Frame = 2

Query:  134 GNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLK 430
            G+V KGK +F+ +CSQCHTVEKGG HKTGPNL+GLFGRKTGQAPGY YTAANKNKGI+WG DTL EYL +P+KYIPGTKM+F G+KK++ERAD+IAYLK
Sbjct:    2 GDVEKGKKIFIMKCSQCHTVEKGGKHKTGPNLHGLFGRKTGQAPGYSYTAANKNKGIIWGEDTLMEYLENPKKYIPGTKMIFVGIKKKEERADLIAYLK 100

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BLAST of Cytochrome c vs. Ensembl Celegans
Match: cyc-2.2 (Probable cytochrome c 2.2 [Source:UniProtKB/Swiss-Prot;Acc:Q23240])

HSP 1 Score: 141.354 bits (355), Expect = 1.638e-43
Identity = 64/103 (62.14%), Postives = 79/103 (76.70%), Query Frame = 2

Query:  122 TVPEGNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLK 430
             +PEG+  KGK +F QRC QCH V      KTGP LNG+ GR++GQ  G+DY+AANKNKG+VW   TLF+YL DP+KYIPGTKMVFAGLKK  ERAD+I +++
Sbjct:   13 AIPEGDNEKGKKIFKQRCEQCHVVN-SLQTKTGPTLNGVIGRQSGQVAGFDYSAANKNKGVVWDRQTLFDYLADPKKYIPGTKMVFAGLKKADERADLIKFIE 114

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BLAST of Cytochrome c vs. Ensembl Celegans
Match: cyc-2.1 (Cytochrome c 2.1 [Source:UniProtKB/Swiss-Prot;Acc:P19974])

HSP 1 Score: 135.961 bits (341), Expect = 1.364e-41
Identity = 62/102 (60.78%), Postives = 79/102 (77.45%), Query Frame = 2

Query:  125 VPEGNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLK 430
            +P G+  KGK ++ QRC QCH V+   A KTGP L+G+ GR +G   G+DY+AANKNKG+VW  +TLFEYL +P+KYIPGTKMVFAGLKK  ERAD+I Y++
Sbjct:    4 IPAGDYEKGKKVYKQRCLQCHVVD-STATKTGPTLHGVIGRTSGTVSGFDYSAANKNKGVVWTRETLFEYLLNPKKYIPGTKMVFAGLKKADERADLIKYIE 104

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Query:  125 VPEGNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLK 430
            +P G+  KGK ++ QRC QCH V+   A KTGP L+G+ GR +G   G+DY+AANKNKG+VW  +TLFEYL +P+KYIPGTKMVFAGLKK  ERAD+I Y++
Sbjct:    4 IPAGDYEKGKKVYKQRCLQCHVVD-STATKTGPTLHGVIGRTSGTVSGFDYSAANKNKGVVWTRETLFEYLLNPKKYIPGTKMVFAGLKKADERADLIKYIE 104

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Query:  125 VPEGNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLK 430
            +P G+  KGK ++ QRC QCH V+   A KTGP L+G+ GR +G   G+DY+AANKNKG+VW  +TLFEYL +P+KYIPGTKMVFAGLKK  ERAD+I Y++
Sbjct:    4 IPAGDYEKGKKVYKQRCLQCHVVD-STATKTGPTLHGVIGRTSGTVSGFDYSAANKNKGVVWTRETLFEYLLNPKKYIPGTKMVFAGLKKADERADLIKYIE 104

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BLAST of Cytochrome c vs. Ensembl Fly
Match: Cyt-c-p (gene:FBgn0284248 transcript:FBtr0080889)

HSP 1 Score: 169.474 bits (428), Expect = 8.664e-55
Identity = 80/108 (74.07%), Postives = 88/108 (81.48%), Query Frame = 2

Query:  119 MTVPEGNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLKDATK 442
            M VP G+V KGK LFVQRC+QCHTVE GG HK GPNL+GL GRKTGQA G+ YT ANK KGI W  DTLFEYL +P+KYIPGTKM+FAGLKK  ER D+IAYLK ATK
Sbjct:    1 MGVPAGDVEKGKKLFVQRCAQCHTVEAGGKHKVGPNLHGLIGRKTGQAAGFAYTDANKAKGITWNEDTLFEYLENPKKYIPGTKMIFAGLKKPNERGDLIAYLKSATK 108

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BLAST of Cytochrome c vs. Ensembl Fly
Match: Cyt-c-p (gene:FBgn0284248 transcript:FBtr0344849)

HSP 1 Score: 169.474 bits (428), Expect = 8.664e-55
Identity = 80/108 (74.07%), Postives = 88/108 (81.48%), Query Frame = 2

Query:  119 MTVPEGNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLKDATK 442
            M VP G+V KGK LFVQRC+QCHTVE GG HK GPNL+GL GRKTGQA G+ YT ANK KGI W  DTLFEYL +P+KYIPGTKM+FAGLKK  ER D+IAYLK ATK
Sbjct:    1 MGVPAGDVEKGKKLFVQRCAQCHTVEAGGKHKVGPNLHGLIGRKTGQAAGFAYTDANKAKGITWNEDTLFEYLENPKKYIPGTKMIFAGLKKPNERGDLIAYLKSATK 108

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BLAST of Cytochrome c vs. Ensembl Fly
Match: Cyt-c-d (gene:FBgn0086907 transcript:FBtr0080888)

HSP 1 Score: 136.346 bits (342), Expect = 8.550e-42
Identity = 64/99 (64.65%), Postives = 74/99 (74.75%), Query Frame = 2

Query:  134 GNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLK 430
            G+   GK +FVQ+C+QCHT E GG HK GPNL G+ GRK G A GY YT AN  KG+ W    L EYL DP+KYIPGTKMVFAGLKK +ERAD+IA+LK
Sbjct:    4 GDAENGKKIFVQKCAQCHTYEVGGKHKVGPNLGGVVGRKCGTAAGYKYTDANIKKGVTWTEGNLDEYLKDPKKYIPGTKMVFAGLKKAEERADLIAFLK 102

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BLAST of Cytochrome c vs. Ensembl Fly
Match: Cyt-c-d (gene:FBgn0086907 transcript:FBtr0335141)

HSP 1 Score: 136.346 bits (342), Expect = 8.550e-42
Identity = 64/99 (64.65%), Postives = 74/99 (74.75%), Query Frame = 2

Query:  134 GNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLK 430
            G+   GK +FVQ+C+QCHT E GG HK GPNL G+ GRK G A GY YT AN  KG+ W    L EYL DP+KYIPGTKMVFAGLKK +ERAD+IA+LK
Sbjct:    4 GDAENGKKIFVQKCAQCHTYEVGGKHKVGPNLGGVVGRKCGTAAGYKYTDANIKKGVTWTEGNLDEYLKDPKKYIPGTKMVFAGLKKAEERADLIAFLK 102

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BLAST of Cytochrome c vs. Ensembl Zebrafish
Match: cycsb (cytochrome c, somatic b [Source:NCBI gene;Acc:415158])

HSP 1 Score: 165.622 bits (418), Expect = 4.232e-53
Identity = 76/102 (74.51%), Postives = 88/102 (86.27%), Query Frame = 2

Query:  134 GNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLKDAT 439
            G+V KGK +FVQ+C+QCHTVE GG HK GPNL GLFGRKTGQA G+ YT ANK+KGIVWG DTL EYL +P+KYIPGTKM+FAG+KK+ ERAD+IAYLK AT
Sbjct:    2 GDVEKGKKVFVQKCAQCHTVENGGKHKVGPNLWGLFGRKTGQAEGFSYTDANKSKGIVWGEDTLMEYLENPKKYIPGTKMIFAGIKKKGERADLIAYLKSAT 103

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BLAST of Cytochrome c vs. Ensembl Zebrafish
Match: cycsa (cytochrome c, somatic a [Source:ZFIN;Acc:ZDB-GENE-060503-627])

HSP 1 Score: 64.3142 bits (155), Expect = 6.715e-14
Identity = 31/55 (56.36%), Postives = 38/55 (69.09%), Query Frame = 2

Query:  131 EGNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKN 295
            E ++ KGK +FVQ+CSQCHT+E  G HK GPNL GLFGR TG+   +  TA  K 
Sbjct:    3 ERDLEKGKKIFVQKCSQCHTIEICGKHKVGPNLYGLFGRMTGRV--HRVTATQKT 55

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BLAST of Cytochrome c vs. Ensembl Xenopus
Match: brd7 (bromodomain containing 7 [Source:Xenbase;Acc:XB-GENE-1017005])

HSP 1 Score: 170.629 bits (431), Expect = 5.279e-55
Identity = 78/102 (76.47%), Postives = 91/102 (89.22%), Query Frame = 2

Query:  134 GNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLKDAT 439
            G+V KGK +FVQ+C+QCHTVEK G HKTGPNL GLFGRKTGQAPG+ YT ANK+KGIVWG DTLFEYL +P+KYIPGTKM+FAG+KK+ ERAD+IAYLK +T
Sbjct:    2 GDVEKGKKIFVQKCAQCHTVEKTGKHKTGPNLWGLFGRKTGQAPGFSYTDANKSKGIVWGEDTLFEYLENPKKYIPGTKMIFAGIKKKNERADLIAYLKKST 103

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BLAST of Cytochrome c vs. Ensembl Xenopus
Match: pgr (progesterone receptor [Source:Xenbase;Acc:XB-GENE-484457])

HSP 1 Score: 164.081 bits (414), Expect = 2.236e-52
Identity = 75/102 (73.53%), Postives = 87/102 (85.29%), Query Frame = 2

Query:  134 GNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLKDAT 439
            G+  KGK +FVQ+CSQCHTVEKGG HKTGPNL+GLFGRKTGQA G+ YT ANKNKGIVW   TL EYL +P+KYIPGTKM+FAG+KK+ ER D+IAYLK +T
Sbjct:    2 GDAEKGKKIFVQKCSQCHTVEKGGKHKTGPNLHGLFGRKTGQAEGFSYTDANKNKGIVWDEGTLLEYLENPKKYIPGTKMIFAGIKKKGERQDLIAYLKQST 103

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BLAST of Cytochrome c vs. Ensembl Mouse
Match: Gm10053 (predicted gene 10053 [Source:MGI Symbol;Acc:MGI:3704493])

HSP 1 Score: 170.244 bits (430), Expect = 5.928e-55
Identity = 78/102 (76.47%), Postives = 90/102 (88.24%), Query Frame = 2

Query:  134 GNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLKDAT 439
            G+V KGK +FVQ+C+QCHTVEKGG HKTGPNL+GLFGRKTGQA G+ YT ANKNKGI WG DTL EYL +P+KYIPGTKM+FAG+KK+ ERAD+IAYLK AT
Sbjct:    2 GDVEKGKKIFVQKCAQCHTVEKGGKHKTGPNLHGLFGRKTGQAAGFSYTDANKNKGITWGEDTLMEYLENPKKYIPGTKMIFAGIKKKGERADLIAYLKKAT 103

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BLAST of Cytochrome c vs. Ensembl Mouse
Match: Cycs (cytochrome c, somatic [Source:MGI Symbol;Acc:MGI:88578])

HSP 1 Score: 170.244 bits (430), Expect = 5.928e-55
Identity = 78/102 (76.47%), Postives = 90/102 (88.24%), Query Frame = 2

Query:  134 GNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLKDAT 439
            G+V KGK +FVQ+C+QCHTVEKGG HKTGPNL+GLFGRKTGQA G+ YT ANKNKGI WG DTL EYL +P+KYIPGTKM+FAG+KK+ ERAD+IAYLK AT
Sbjct:    2 GDVEKGKKIFVQKCAQCHTVEKGGKHKTGPNLHGLFGRKTGQAAGFSYTDANKNKGITWGEDTLMEYLENPKKYIPGTKMIFAGIKKKGERADLIAYLKKAT 103

[Close]

BLAST of Cytochrome c vs. Ensembl Mouse
Match: Cyct (cytochrome c, testis [Source:MGI Symbol;Acc:MGI:88579])

HSP 1 Score: 162.925 bits (411), Expect = 5.224e-52
Identity = 72/102 (70.59%), Postives = 86/102 (84.31%), Query Frame = 2

Query:  134 GNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLKDAT 439
            G+   GK +FVQ+C+QCHTVEKGG HKTGPNL GLFGRKTGQAPG+ YT ANKNKG++W  +TL EYL +P+KYIPGTKM+FAG+KK+ ER D+I YLK AT
Sbjct:    2 GDAEAGKKIFVQKCAQCHTVEKGGKHKTGPNLWGLFGRKTGQAPGFSYTDANKNKGVIWSEETLMEYLENPKKYIPGTKMIFAGIKKKSEREDLIKYLKQAT 103

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BLAST of Cytochrome c vs. UniProt/SwissProt
Match: sp|P00018|CYC_DRONO (Cytochrome c OS=Dromaius novaehollandiae OX=8790 GN=CYC PE=1 SV=2)

HSP 1 Score: 177.563 bits (449), Expect = 6.237e-57
Identity = 80/102 (78.43%), Postives = 91/102 (89.22%), Query Frame = 2

Query:  134 GNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLKDAT 439
            G++ KGK +FVQ+CSQCHTVEKGG HKTGPNLNGLFGRKTGQA G+ YT ANKNKGI WG DTL EYL +P+KYIPGTKM+FAG+KK+ ERAD+IAYLKDAT
Sbjct:    2 GDIEKGKKIFVQKCSQCHTVEKGGKHKTGPNLNGLFGRKTGQAEGFSYTDANKNKGITWGEDTLMEYLENPKKYIPGTKMIFAGIKKKSERADLIAYLKDAT 103

[Close]

BLAST of Cytochrome c vs. UniProt/SwissProt
Match: sp|Q5RFH4|CYC_PONAB (Cytochrome c OS=Pongo abelii OX=9601 GN=CYCS PE=3 SV=3)

HSP 1 Score: 176.022 bits (445), Expect = 1.884e-56
Identity = 79/102 (77.45%), Postives = 92/102 (90.20%), Query Frame = 2

Query:  134 GNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLKDAT 439
            G+V KGK +F+ +CSQCHTVEKGG HKTGPNL+GLFGRKTGQAPGY YTAANKNKGI+WG DTL EYL +P+KYIPGTKM+F G+KK++ERAD+IAYLK AT
Sbjct:    2 GDVEKGKKIFIMKCSQCHTVEKGGKHKTGPNLHGLFGRKTGQAPGYSYTAANKNKGIIWGEDTLMEYLENPKKYIPGTKMIFVGIKKKEERADLIAYLKKAT 103

[Close]

BLAST of Cytochrome c vs. UniProt/SwissProt
Match: sp|P99998|CYC_PANTR (Cytochrome c OS=Pan troglodytes OX=9598 GN=CYCS PE=1 SV=2)

HSP 1 Score: 176.022 bits (445), Expect = 1.884e-56
Identity = 79/102 (77.45%), Postives = 92/102 (90.20%), Query Frame = 2

Query:  134 GNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLKDAT 439
            G+V KGK +F+ +CSQCHTVEKGG HKTGPNL+GLFGRKTGQAPGY YTAANKNKGI+WG DTL EYL +P+KYIPGTKM+F G+KK++ERAD+IAYLK AT
Sbjct:    2 GDVEKGKKIFIMKCSQCHTVEKGGKHKTGPNLHGLFGRKTGQAPGYSYTAANKNKGIIWGEDTLMEYLENPKKYIPGTKMIFVGIKKKEERADLIAYLKKAT 103

[Close]

BLAST of Cytochrome c vs. UniProt/SwissProt
Match: sp|P99999|CYC_HUMAN (Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS PE=1 SV=2)

HSP 1 Score: 176.022 bits (445), Expect = 1.884e-56
Identity = 79/102 (77.45%), Postives = 92/102 (90.20%), Query Frame = 2

Query:  134 GNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLKDAT 439
            G+V KGK +F+ +CSQCHTVEKGG HKTGPNL+GLFGRKTGQAPGY YTAANKNKGI+WG DTL EYL +P+KYIPGTKM+F G+KK++ERAD+IAYLK AT
Sbjct:    2 GDVEKGKKIFIMKCSQCHTVEKGGKHKTGPNLHGLFGRKTGQAPGYSYTAANKNKGIIWGEDTLMEYLENPKKYIPGTKMIFVGIKKKEERADLIAYLKKAT 103

[Close]

BLAST of Cytochrome c vs. UniProt/SwissProt
Match: sp|Q6WUX8|CYC_GORGO (Cytochrome c OS=Gorilla gorilla gorilla OX=9595 GN=CYCS PE=3 SV=3)

HSP 1 Score: 176.022 bits (445), Expect = 1.884e-56
Identity = 79/102 (77.45%), Postives = 92/102 (90.20%), Query Frame = 2

Query:  134 GNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLKDAT 439
            G+V KGK +F+ +CSQCHTVEKGG HKTGPNL+GLFGRKTGQAPGY YTAANKNKGI+WG DTL EYL +P+KYIPGTKM+F G+KK++ERAD+IAYLK AT
Sbjct:    2 GDVEKGKKIFIMKCSQCHTVEKGGKHKTGPNLHGLFGRKTGQAPGYSYTAANKNKGIIWGEDTLMEYLENPKKYIPGTKMIFVGIKKKEERADLIAYLKKAT 103

[Close]

BLAST of Cytochrome c vs. TrEMBL
Match: A0A267GGN7 (Cytochrome c domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig033436g1 PE=3 SV=1)

HSP 1 Score: 189.889 bits (481), Expect = 2.536e-59
Identity = 87/106 (82.08%), Postives = 99/106 (93.40%), Query Frame = 2

Query:  125 VPEGNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLKDATK 442
            +P+G+V KGK +F+QRC QCHTVEKGGAHKTGPNLNGLFGRKTGQAPG+ YT ANK+KGI WGPDTLFEYL +P+KYIPGTKMVFAGLKKEK+RAD+IAYLK+ATK
Sbjct:    8 IPDGDVEKGKKIFIQRCLQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGFSYTDANKSKGITWGPDTLFEYLLNPKKYIPGTKMVFAGLKKEKDRADLIAYLKEATK 113

[Close]

BLAST of Cytochrome c vs. TrEMBL
Match: A0A267G6N2 (Cytochrome c domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig033436g2 PE=3 SV=1)

HSP 1 Score: 189.889 bits (481), Expect = 2.904e-59
Identity = 87/106 (82.08%), Postives = 99/106 (93.40%), Query Frame = 2

Query:  125 VPEGNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLKDATK 442
            +P+G+V KGK +F+QRC QCHTVEKGGAHKTGPNLNGLFGRKTGQAPG+ YT ANK+KGI WGPDTLFEYL +P+KYIPGTKMVFAGLKKEK+RAD+IAYLK+ATK
Sbjct:    4 IPDGDVEKGKKIFIQRCLQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGFSYTDANKSKGITWGPDTLFEYLLNPKKYIPGTKMVFAGLKKEKDRADLIAYLKEATK 109

[Close]

BLAST of Cytochrome c vs. TrEMBL
Match: A0A074ZFW7 (Cytochrome OS=Opisthorchis viverrini OX=6198 GN=T265_09703 PE=3 SV=1)

HSP 1 Score: 186.422 bits (472), Expect = 5.839e-58
Identity = 86/108 (79.63%), Postives = 98/108 (90.74%), Query Frame = 2

Query:  119 MTVPEGNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLKDATK 442
            MTVPEG+  KGK LFVQRC+QCHTVEKGG+HKTGPNLNGLFGRKTGQAPGY YTAANK+KGI W  +TLFEYL +P+KYIPGTKMVFAGLKK ++RA +IAYLK++TK
Sbjct:    1 MTVPEGDSEKGKKLFVQRCAQCHTVEKGGSHKTGPNLNGLFGRKTGQAPGYSYTAANKDKGITWTEETLFEYLENPKKYIPGTKMVFAGLKKAEDRAHLIAYLKESTK 108

[Close]

BLAST of Cytochrome c vs. TrEMBL
Match: A0A4S2MDB7 (Cytochrome c domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_002248 PE=3 SV=1)

HSP 1 Score: 186.037 bits (471), Expect = 8.198e-58
Identity = 85/108 (78.70%), Postives = 98/108 (90.74%), Query Frame = 2

Query:  119 MTVPEGNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLKDATK 442
            MTVPEG+  KGK LFVQRC+QCHTVEKGG+HKTGPNLNGLFGRKTGQAPGY YTAAN++KGI W  +TLFEYL +P+KYIPGTKMVFAGLKK  +RA++IAYLK++TK
Sbjct:    1 MTVPEGDSEKGKKLFVQRCAQCHTVEKGGSHKTGPNLNGLFGRKTGQAPGYSYTAANRDKGITWTEETLFEYLENPKKYIPGTKMVFAGLKKADDRANLIAYLKESTK 108

[Close]

BLAST of Cytochrome c vs. TrEMBL
Match: A0A419QF28 (Cytochrome c OS=Clonorchis sinensis OX=79923 GN=CSKR_2411s PE=3 SV=1)

HSP 1 Score: 185.652 bits (470), Expect = 1.066e-57
Identity = 86/108 (79.63%), Postives = 97/108 (89.81%), Query Frame = 2

Query:  119 MTVPEGNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLKDATK 442
            MTVPEG+  KGK LFVQRC+QCHTVEKGG+HKTGPNLNGLFGRKTGQAPGY YTAANK+KGI W  +TLFEYL  P+KYIPGTKMVFAGLKK ++RA +IAYLK++TK
Sbjct:    1 MTVPEGDSDKGKKLFVQRCAQCHTVEKGGSHKTGPNLNGLFGRKTGQAPGYSYTAANKDKGITWTEETLFEYLESPKKYIPGTKMVFAGLKKAEDRAHLIAYLKESTK 108

[Close]

BLAST of Cytochrome c vs. Ensembl Cavefish
Match: ENSAMXT00000039245.1 (cytochrome c [Source:NCBI gene;Acc:103040542])

HSP 1 Score: 159.844 bits (403), Expect = 5.668e-51
Identity = 73/102 (71.57%), Postives = 86/102 (84.31%), Query Frame = 2

Query:  134 GNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLKDAT 439
            G+V KGK +FVQ+C+QCHTVE GG HK GPNL GLFGRKTGQA G+ YT ANK+KGI W  DTL EYL +P+KYIPGTKM+FAG+KK+ ERAD+IAYLK +T
Sbjct:    2 GDVEKGKKVFVQKCAQCHTVENGGKHKVGPNLWGLFGRKTGQAEGFSYTDANKSKGITWNEDTLMEYLENPKKYIPGTKMIFAGIKKKGERADLIAYLKAST 103

[Close]

BLAST of Cytochrome c vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010092.1 (pep scaffold:Pmarinus_7.0:GL476758:13769:19979:-1 gene:ENSPMAG00000009134.1 transcript:ENSPMAT00000010092.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 166.392 bits (420), Expect = 2.995e-54
Identity = 74/102 (72.55%), Postives = 90/102 (88.24%), Query Frame = 2

Query:  134 GNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLKDAT 439
            G+V KGK +FVQ+CSQCH+VEKGG HKTGPNL+G+FGR+TGQAPG+ YT AN++KGIVW  DTLF YL +P+KYIPGTKM+FAG+KKE ER D+IAYLK +T
Sbjct:    2 GDVEKGKKVFVQKCSQCHSVEKGGKHKTGPNLSGIFGRQTGQAPGFSYTDANRDKGIVWNEDTLFLYLENPKKYIPGTKMIFAGIKKEGERKDLIAYLKQST 103

[Close]

BLAST of Cytochrome c vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009796.1 (pep scaffold:Pmarinus_7.0:GL483755:2404:12631:-1 gene:ENSPMAG00000008855.1 transcript:ENSPMAT00000009796.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 165.622 bits (418), Expect = 5.347e-54
Identity = 75/102 (73.53%), Postives = 89/102 (87.25%), Query Frame = 2

Query:  134 GNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLKDAT 439
            G+V KGK +FVQ+C+QCHTVEK G HKTGPNL+GLFGRKTGQAPG+ YT ANK+KGIVW  +TLF YL +P+KYIPGTKM+FAG+KKE ER D+IAYLK +T
Sbjct:    2 GDVEKGKKVFVQKCAQCHTVEKSGKHKTGPNLSGLFGRKTGQAPGFSYTDANKSKGIVWNEETLFVYLENPKKYIPGTKMIFAGIKKEGERKDLIAYLKKST 103

[Close]

BLAST of Cytochrome c vs. Ensembl Yeast
Match: CYC1 (Cytochrome c, isoform 1; also known as iso-1-cytochrome c; electron carrier of mitochondrial intermembrane space that transfers electrons from ubiquinone-cytochrome c oxidoreductase to cytochrome c oxidase during cellular respiration; CYC1 has a paralog, CYC7, that arose from the whole genome duplication; human homolog CYC1 can complement yeast null mutant; mutations in human CYC1 cause insulin-responsive hyperglycemia [Source:SGD;Acc:S000003809])

HSP 1 Score: 137.502 bits (345), Expect = 6.215e-43
Identity = 63/101 (62.38%), Postives = 76/101 (75.25%), Query Frame = 2

Query:  134 GNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLKDA 436
            G+  KG +LF  RC QCHTVEKGG HK GPNL+G+FGR +GQA GY YT AN  K ++W  + + EYL +P+KYIPGTKM F GLKKEK+R D+I YLK A
Sbjct:    7 GSAKKGATLFKTRCLQCHTVEKGGPHKVGPNLHGIFGRHSGQAEGYSYTDANIKKNVLWDENNMSEYLTNPKKYIPGTKMAFGGLKKEKDRNDLITYLKKA 107

[Close]

BLAST of Cytochrome c vs. Ensembl Yeast
Match: CYC7 (Cytochrome c isoform 2, expressed under hypoxic conditions; also known as iso-2-cytochrome c; electron carrier of the mitochondrial intermembrane space that transfers electrons from ubiquinone-cytochrome c oxidoreductase to cytochrome c oxidase during cellular respiration; protein abundance increases in response to DNA replication stress; CYC7 has a paralog, CYC1, that arose from the whole genome duplication [Source:SGD;Acc:S000000765])

HSP 1 Score: 136.346 bits (342), Expect = 1.506e-42
Identity = 61/103 (59.22%), Postives = 77/103 (74.76%), Query Frame = 2

Query:  134 GNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLKDATK 442
            G+  KG +LF  RC QCHT+E+GG +K GPNL+G+FGR +GQ  GY YT AN NK + W  D++ EYL +P+KYIPGTKM FAGLKKEK+R D+I Y+  A K
Sbjct:   11 GSAKKGATLFKTRCQQCHTIEEGGPNKVGPNLHGIFGRHSGQVKGYSYTDANINKNVKWDEDSMSEYLTNPKKYIPGTKMAFAGLKKEKDRNDLITYMTKAAK 113

[Close]

BLAST of Cytochrome c vs. Ensembl Nematostella
Match: EDO46857 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RP70])

HSP 1 Score: 160.614 bits (405), Expect = 1.065e-51
Identity = 73/107 (68.22%), Postives = 87/107 (81.31%), Query Frame = 2

Query:  119 MTVPEGNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLKDAT 439
            M++PEG+ TKG  +F  +CS CHTVE GG HKTGPNL+G+FGRKTGQA GY YT AN  KGI W  +TLF YL +P+KYIPGTKMVFAG+KK+ ERAD+IAYLK+ T
Sbjct:    1 MSIPEGDATKGAKIFKTKCSACHTVEAGGKHKTGPNLHGMFGRKTGQAEGYTYTPANLTKGITWNDETLFVYLENPKKYIPGTKMVFAGIKKKNERADLIAYLKETT 107

[Close]

BLAST of Cytochrome c vs. Ensembl Nematostella
Match: EDO43318 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZ03])

HSP 1 Score: 155.992 bits (393), Expect = 7.884e-50
Identity = 71/102 (69.61%), Postives = 83/102 (81.37%), Query Frame = 2

Query:  134 GNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLKDAT 439
            G+ TKG  +F  +C+QCHTVE GG HKTGPNL+GLFGRKTGQA G+ YT AN+NKGI WG DTL  YL +P+KYIPGTKMVFAG+KK+ ER D+IAYLK  T
Sbjct:    2 GDATKGAKVFKTKCAQCHTVEAGGKHKTGPNLHGLFGRKTGQAEGFSYTTANQNKGITWGEDTLMVYLENPKKYIPGTKMVFAGIKKKNERLDLIAYLKQET 103

[Close]

BLAST of Cytochrome c vs. Ensembl Medaka
Match: ENSORLT00000023225.2 (cytochrome c iso-1/iso-2 [Source:NCBI gene;Acc:101171965])

HSP 1 Score: 160.229 bits (404), Expect = 4.729e-51
Identity = 73/102 (71.57%), Postives = 86/102 (84.31%), Query Frame = 2

Query:  134 GNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLKDAT 439
            G+V KGK +FVQ+C+QCHTVE+GG HK GPNL GLFGRKTGQAPGY YT ANK+KGI W  DTL  YL +P+KYIPGTKM+FAG+KK+ ER D+I+YLK AT
Sbjct:    2 GDVDKGKKVFVQKCAQCHTVEEGGKHKVGPNLWGLFGRKTGQAPGYSYTDANKSKGITWNEDTLMVYLENPKKYIPGTKMIFAGIKKKGERQDLISYLKSAT 103

[Close]

BLAST of Cytochrome c vs. Ensembl Medaka
Match: cycsb (cytochrome c iso-1/iso-2 [Source:NCBI gene;Acc:101165110])

HSP 1 Score: 159.844 bits (403), Expect = 6.997e-51
Identity = 71/102 (69.61%), Postives = 86/102 (84.31%), Query Frame = 2

Query:  134 GNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLKDAT 439
            G++ KGK  FVQ+C+QCHTVE+GG HK GPNL GLFGR+TGQAPGY YT ANK+KGI+W  +TL  YL +P+KYIPGTKM+FAG+KK+ ER D+IAYLK AT
Sbjct:    3 GDIEKGKKAFVQKCAQCHTVEQGGKHKVGPNLWGLFGRQTGQAPGYSYTDANKSKGIIWNEETLMIYLENPKKYIPGTKMIFAGIKKKNERVDLIAYLKSAT 104

[Close]

BLAST of Cytochrome c vs. Planmine SMEST
Match: SMESG000045852.1 (SMESG000045852.1)

HSP 1 Score: 225.713 bits (574), Expect = 5.284e-77
Identity = 108/108 (100.00%), Postives = 108/108 (100.00%), Query Frame = 2

Query:  119 MTVPEGNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLKDATK 442
            MTVPEGNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLKDATK
Sbjct:    1 MTVPEGNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPGYDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADIIAYLKDATK 108

The following BLAST results are available for this feature:

BLAST of Cytochrome c vs. Ensembl Human
BLAST of Cytochrome c vs. Ensembl Celegans
BLAST of Cytochrome c vs. Ensembl Fly
BLAST of Cytochrome c vs. Ensembl Zebrafish
BLAST of Cytochrome c vs. Ensembl Xenopus
BLAST of Cytochrome c vs. Ensembl Mouse
BLAST of Cytochrome c vs. UniProt/SwissProt
BLAST of Cytochrome c vs. TrEMBL
BLAST of Cytochrome c vs. Ensembl Cavefish
BLAST of Cytochrome c vs. Ensembl Sea Lamprey
BLAST of Cytochrome c vs. Ensembl Yeast
BLAST of Cytochrome c vs. Ensembl Nematostella
BLAST of Cytochrome c vs. Ensembl Medaka
BLAST of Cytochrome c vs. Planmine SMEST

BLAST of Cytochrome c vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 4


Match Name	E-value	Identity	Description
CYCS	3.923e-57	77.45	cytochrome c, somatic [Source:HGNC Symbol;Acc:HGNC...	[more]
CYCS	3.923e-57	77.45	cytochrome c, somatic [Source:HGNC Symbol;Acc:HGNC...	[more]
CYCS	3.923e-57	77.45	cytochrome c, somatic [Source:HGNC Symbol;Acc:HGNC...	[more]
CYCS	1.281e-55	77.78	cytochrome c, somatic [Source:HGNC Symbol;Acc:HGNC...	[more]

BLAST of Cytochrome c vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 4


Match Name	E-value	Identity	Description
cyc-2.2	1.638e-43	62.14	Probable cytochrome c 2.2 [Source:UniProtKB/Swiss...	[more]
cyc-2.1	1.364e-41	60.78	Cytochrome c 2.1 [Source:UniProtKB/Swiss-Prot;Acc...	[more]
cyc-2.1	1.364e-41	60.78	Cytochrome c 2.1 [Source:UniProtKB/Swiss-Prot;Acc...	[more]
cyc-2.1	1.364e-41	60.78	Cytochrome c 2.1 [Source:UniProtKB/Swiss-Prot;Acc...	[more]

BLAST of Cytochrome c vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4


Match Name	E-value	Identity	Description
Cyt-c-p	8.664e-55	74.07	gene:FBgn0284248 transcript:FBtr0080889	[more]
Cyt-c-p	8.664e-55	74.07	gene:FBgn0284248 transcript:FBtr0344849	[more]
Cyt-c-d	8.550e-42	64.65	gene:FBgn0086907 transcript:FBtr0080888	[more]
Cyt-c-d	8.550e-42	64.65	gene:FBgn0086907 transcript:FBtr0335141	[more]

BLAST of Cytochrome c vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2


Match Name	E-value	Identity	Description
cycsb	4.232e-53	74.51	cytochrome c, somatic b [Source:NCBI gene;Acc:4151...	[more]
cycsa	6.715e-14	56.36	cytochrome c, somatic a [Source:ZFIN;Acc:ZDB-GENE-...	[more]

BLAST of Cytochrome c vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2


Match Name	E-value	Identity	Description
brd7	5.279e-55	76.47	bromodomain containing 7 [Source:Xenbase;Acc:XB-GE...	[more]
pgr	2.236e-52	73.53	progesterone receptor [Source:Xenbase;Acc:XB-GENE-...	[more]

BLAST of Cytochrome c vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3


Match Name	E-value	Identity	Description
Gm10053	5.928e-55	76.47	predicted gene 10053 [Source:MGI Symbol;Acc:MGI:37...	[more]
Cycs	5.928e-55	76.47	cytochrome c, somatic [Source:MGI Symbol;Acc:MGI:8...	[more]
Cyct	5.224e-52	70.59	cytochrome c, testis [Source:MGI Symbol;Acc:MGI:88...	[more]

BLAST of Cytochrome c vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P00018\|CYC_DRONO	6.237e-57	78.43	Cytochrome c OS=Dromaius novaehollandiae OX=8790 G...	[more]
sp\|Q5RFH4\|CYC_PONAB	1.884e-56	77.45	Cytochrome c OS=Pongo abelii OX=9601 GN=CYCS PE=3 ...	[more]
sp\|P99998\|CYC_PANTR	1.884e-56	77.45	Cytochrome c OS=Pan troglodytes OX=9598 GN=CYCS PE...	[more]
sp\|P99999\|CYC_HUMAN	1.884e-56	77.45	Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS PE=1 ...	[more]
sp\|Q6WUX8\|CYC_GORGO	1.884e-56	77.45	Cytochrome c OS=Gorilla gorilla gorilla OX=9595 GN...	[more]

BLAST of Cytochrome c vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A267GGN7	2.536e-59	82.08	Cytochrome c domain-containing protein (Fragment) ...	[more]
A0A267G6N2	2.904e-59	82.08	Cytochrome c domain-containing protein OS=Macrosto...	[more]
A0A074ZFW7	5.839e-58	79.63	Cytochrome OS=Opisthorchis viverrini OX=6198 GN=T2...	[more]
A0A4S2MDB7	8.198e-58	78.70	Cytochrome c domain-containing protein OS=Opisthor...	[more]
A0A419QF28	1.066e-57	79.63	Cytochrome c OS=Clonorchis sinensis OX=79923 GN=CS...	[more]

BLAST of Cytochrome c vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ENSAMXT00000039245.1	5.668e-51	71.57	cytochrome c [Source:NCBI gene;Acc:103040542]	[more]

BLAST of Cytochrome c vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
ENSPMAT00000010092.1	2.995e-54	72.55	pep scaffold:Pmarinus_7.0:GL476758:13769:19979:-1 ...	[more]
ENSPMAT00000009796.1	5.347e-54	73.53	pep scaffold:Pmarinus_7.0:GL483755:2404:12631:-1 g...	[more]

BLAST of Cytochrome c vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2


Match Name	E-value	Identity	Description
CYC1	6.215e-43	62.38	Cytochrome c, isoform 1; also known as iso-1-cytoc...	[more]
CYC7	1.506e-42	59.22	Cytochrome c isoform 2, expressed under hypoxic co...	[more]

BLAST of Cytochrome c vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2


Match Name	E-value	Identity	Description
EDO46857	1.065e-51	68.22	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO43318	7.884e-50	69.61	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Cytochrome c vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2


Match Name	E-value	Identity	Description
ENSORLT00000023225.2	4.729e-51	71.57	cytochrome c iso-1/iso-2 [Source:NCBI gene;Acc:101...	[more]
cycsb	6.997e-51	69.61	cytochrome c iso-1/iso-2 [Source:NCBI gene;Acc:101...	[more]

BLAST of Cytochrome c vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1


Match Name	E-value	Identity	Description
SMESG000045852.1	5.284e-77	100.00	SMESG000045852.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30021332 ID=SMED30021332|Name=Cytochrome c|organism=Schmidtea mediterranea sexual|type=transcript|length=540bp
GTCGTTTTAGTCAATTATTAAAAATTGTGAAATGTTTTAATTATTTATTT
TTCACATTTTGTTATATAAATATATTAAACACTTCAAACTCAAATATTTT
GTTTTCCATTTTTGTAAAATGACTGTTCCCGAAGGTAATGTTACAAAAGG
CAAAAGTCTATTTGTTCAAAGATGTTCACAATGTCATACAGTTGAAAAAG
GAGGTGCCCATAAAACTGGTCCTAATTTGAATGGGTTATTTGGTCGTAAA
ACTGGGCAAGCACCAGGTTACGATTACACTGCTGCAAATAAAAATAAAGG
CATAGTATGGGGTCCAGATACGTTGTTCGAATATTTACATGATCCTAGAA
AGTACATCCCAGGAACAAAAATGGTTTTTGCTGGATTAAAAAAAGAGAAA
GAACGTGCTGATATAATTGCGTATTTGAAAGATGCAACAAAATAATTTTA
ATTCTAGGAATAGTTTATAGTGTGTTTGAATGTTAATAAAAGAATGCTAA
GTTTTTAATTGTAGATTTATTTAATACATTTTTAATAGGG

protein sequence of SMED30021332-orf-1

>SMED30021332-orf-1 ID=SMED30021332-orf-1|Name=SMED30021332-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=109bp
MTVPEGNVTKGKSLFVQRCSQCHTVEKGGAHKTGPNLNGLFGRKTGQAPG
YDYTAANKNKGIVWGPDTLFEYLHDPRKYIPGTKMVFAGLKKEKERADII
AYLKDATK*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **biological process**
Term	Definition
GO:0022900	electron transport chain
GO:0006915	apoptotic process
GO:0055114	oxidation-reduction process

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000016	pharynx
PLANA:0000026	gut
PLANA:0000070	intestinal phagocyte

Vocabulary: **INTERPRO**
Term	Definition
IPR036909	Cyt_c-like_dom_sf
IPR002327	Cyt_c_1A/1B
IPR009056	Cyt_c-like_dom

Vocabulary: **molecular function**
Term	Definition
GO:0009055	electron carrier activity
GO:0020037	heme binding
GO:0045155	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity
GO:0046872	metal ion binding

Vocabulary: **cellular component**
Term	Definition
GO:0005634	nucleus
GO:0005739	mitochondrion
GO:0005758	mitochondrial intermembrane space
GO:0005829	cytosol
GO:0070469	respiratory chain

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR002327	Cytochrome c, class IA/ IB	PRINTS	PR00604	CYTCHRMECIAB	coord: 31..46 score: 78.21 coord: 97..105 score: 67.08 coord: 47..57 score: 59.81 coord: 18..25 score: 72.66 coord: 80..90 score: 83.86 coord: 61..77 score: 49.2
IPR002327	Cytochrome c, class IA/ IB	PANTHER	PTHR11961	CYTOCHROME C	coord: 5..107
IPR009056	Cytochrome c-like domain	PFAM	PF00034	Cytochrom_C	coord: 9..105 e-value: 1.0E-12 score: 49.0
IPR009056	Cytochrome c-like domain	PROSITE	PS51007	CYTC	coord: 6..107 score: 15.628
IPR036909	Cytochrome c-like domain superfamily	GENE3D	G3DSA:1.10.760.10		coord: 1..106 e-value: 8.8E-43 score: 147.6
IPR036909	Cytochrome c-like domain superfamily	SUPERFAMILY	SSF46626	Cytochrome c	coord: 5..105
None	No IPR available	PANTHER	PTHR11961:SF25	CYTOCHROME C	coord: 5..107