Disks large homolog 1
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30021297 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 11
Homology
BLAST of Disks large homolog 1 vs. Ensembl Human
Match: DLG1 (discs large MAGUK scaffold protein 1 [Source:HGNC Symbol;Acc:HGNC:2900]) HSP 1 Score: 147.517 bits (371), Expect = 1.623e-39 Identity = 136/418 (32.54%), Postives = 201/418 (48.09%), Query Frame = 2
Query: 2 MDIRKDDTERAVNLLKFYXXXXXXXXXXXXXXAMEKLIDTLETPLFSALLDIQEFYEVSL---SSAISGNK--SPVQPVYNDIIPEAKLEVQETPVXXXXXXXXXXXXXXXXXXXXXXXIASPKPVSKVKSNDNYEPEDYP--DYQDPNYNQE-------YEPEANLEDENN--------------------PWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
M +RK DT+RA++LL+ Y+SKL+++E++ L+ ++E++I+ ++ LF AL+DIQEFYEV+L I +K P+QPV E+ P ++ P +S Y+ ED P ++ P E + E NL + N + Y +I L +G G GF++AGG + PH D+ IF+TKIIT GAA DGRL+++D I+ VN+V++ VTH AV+ LK AG + L ++R K P E + E+ LIK GLG SI GG + D+ I ++K+ GG A DG+LQ+GD +L V++ L VTHEEAV LKNT V L +A+
Sbjct: 1 MPVRKQDTQRALHLLEEYRSKLSQTEDRQLRSSIERVINIFQSNLFQALIDIQEFYEVTLLDNPKCIDRSKPSEPIQPVNT-------WEISSLPSSTVTSETL------------------PSSLSPSVEKYRYQDEDTPPQEHISPQITNEVIGPELVHVSEKNLSEIENVHGFVSHSHISPIKVNGTDADYEYEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEVDVRDVTHSKAVEALKEAGSIVRLYVKRRK-------------------------PVSE--------------KIMEIKLIK-GPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNNVCLEEVTHEEAVTALKNTSDFVYLKVAK 353 HSP 2 Score: 73.1738 bits (178), Expect = 2.028e-13 Identity = 48/104 (46.15%), Postives = 63/104 (60.58%), Query Frame = 2
Query: 488 FQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRR-----LKDEYVANETTN 784
+I L KG KG GF++AGG H GDN I+VTKII GAA DG+L+I D +++VN+V LE VTHE AV LKN + L + + + D Y + TN
Sbjct: 267 MEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNNVCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMYMNDGYAPPDITN 370
BLAST of Disks large homolog 1 vs. Ensembl Human
Match: DLG1 (discs large MAGUK scaffold protein 1 [Source:HGNC Symbol;Acc:HGNC:2900]) HSP 1 Score: 147.902 bits (372), Expect = 1.349e-37 Identity = 136/418 (32.54%), Postives = 201/418 (48.09%), Query Frame = 2
Query: 2 MDIRKDDTERAVNLLKFYXXXXXXXXXXXXXXAMEKLIDTLETPLFSALLDIQEFYEVSL---SSAISGNK--SPVQPVYNDIIPEAKLEVQETPVXXXXXXXXXXXXXXXXXXXXXXXIASPKPVSKVKSNDNYEPEDYP--DYQDPNYNQE-------YEPEANLEDENN--------------------PWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
M +RK DT+RA++LL+ Y+SKL+++E++ L+ ++E++I+ ++ LF AL+DIQEFYEV+L I +K P+QPV E+ P ++ P +S Y+ ED P ++ P E + E NL + N + Y +I L +G G GF++AGG + PH D+ IF+TKIIT GAA DGRL+++D I+ VN+V++ VTH AV+ LK AG + L ++R K P E + E+ LIK GLG SI GG + D+ I ++K+ GG A DG+LQ+GD +L V++ L VTHEEAV LKNT V L +A+
Sbjct: 1 MPVRKQDTQRALHLLEEYRSKLSQTEDRQLRSSIERVINIFQSNLFQALIDIQEFYEVTLLDNPKCIDRSKPSEPIQPVNT-------WEISSLPSSTVTSETL------------------PSSLSPSVEKYRYQDEDTPPQEHISPQITNEVIGPELVHVSEKNLSEIENVHGFVSHSHISPIKVNGTDADYEYEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEVDVRDVTHSKAVEALKEAGSIVRLYVKRRK-------------------------PVSE--------------KIMEIKLIK-GPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNNVCLEEVTHEEAVTALKNTSDFVYLKVAK 353 HSP 2 Score: 96.6709 bits (239), Expect = 1.170e-20 Identity = 83/235 (35.32%), Postives = 120/235 (51.06%), Query Frame = 2
Query: 488 FQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRR-----LKDEYVANETTNLHE------------VVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTL 1141
+I L KG KG GF++AGG H GDN I+VTKII GAA DG+L+I D +++VN+V LE VTHE AV LKN + L + + + D Y + TN + Q + YSP + +++ ++ ++ R + GLG +I GG E+ I IS + GG AD+ G L+ GD I+ V+ L +HE+A LKN G+ VT+
Sbjct: 267 MEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNNVCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMYMNDGYAPPDITNSSSQPVDNHVSPSSFLGQTPASPARYSPVSKAVL-----GDDEITREPRKVVLHRGSTGLGFNIVGG------EDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVTI 490
BLAST of Disks large homolog 1 vs. Ensembl Human
Match: DLG1 (discs large MAGUK scaffold protein 1 [Source:HGNC Symbol;Acc:HGNC:2900]) HSP 1 Score: 147.902 bits (372), Expect = 1.349e-37 Identity = 136/418 (32.54%), Postives = 201/418 (48.09%), Query Frame = 2
Query: 2 MDIRKDDTERAVNLLKFYXXXXXXXXXXXXXXAMEKLIDTLETPLFSALLDIQEFYEVSL---SSAISGNK--SPVQPVYNDIIPEAKLEVQETPVXXXXXXXXXXXXXXXXXXXXXXXIASPKPVSKVKSNDNYEPEDYP--DYQDPNYNQE-------YEPEANLEDENN--------------------PWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
M +RK DT+RA++LL+ Y+SKL+++E++ L+ ++E++I+ ++ LF AL+DIQEFYEV+L I +K P+QPV E+ P ++ P +S Y+ ED P ++ P E + E NL + N + Y +I L +G G GF++AGG + PH D+ IF+TKIIT GAA DGRL+++D I+ VN+V++ VTH AV+ LK AG + L ++R K P E + E+ LIK GLG SI GG + D+ I ++K+ GG A DG+LQ+GD +L V++ L VTHEEAV LKNT V L +A+
Sbjct: 1 MPVRKQDTQRALHLLEEYRSKLSQTEDRQLRSSIERVINIFQSNLFQALIDIQEFYEVTLLDNPKCIDRSKPSEPIQPVNT-------WEISSLPSSTVTSETL------------------PSSLSPSVEKYRYQDEDTPPQEHISPQITNEVIGPELVHVSEKNLSEIENVHGFVSHSHISPIKVNGTDADYEYEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEVDVRDVTHSKAVEALKEAGSIVRLYVKRRK-------------------------PVSE--------------KIMEIKLIK-GPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNNVCLEEVTHEEAVTALKNTSDFVYLKVAK 353 HSP 2 Score: 96.6709 bits (239), Expect = 1.170e-20 Identity = 83/235 (35.32%), Postives = 120/235 (51.06%), Query Frame = 2
Query: 488 FQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRR-----LKDEYVANETTNLHE------------VVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTL 1141
+I L KG KG GF++AGG H GDN I+VTKII GAA DG+L+I D +++VN+V LE VTHE AV LKN + L + + + D Y + TN + Q + YSP + +++ ++ ++ R + GLG +I GG E+ I IS + GG AD+ G L+ GD I+ V+ L +HE+A LKN G+ VT+
Sbjct: 267 MEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNNVCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMYMNDGYAPPDITNSSSQPVDNHVSPSSFLGQTPASPARYSPVSKAVL-----GDDEITREPRKVVLHRGSTGLGFNIVGG------EDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVTI 490
BLAST of Disks large homolog 1 vs. Ensembl Human
Match: DLG1 (discs large MAGUK scaffold protein 1 [Source:HGNC Symbol;Acc:HGNC:2900]) HSP 1 Score: 147.517 bits (371), Expect = 1.664e-37 Identity = 136/418 (32.54%), Postives = 201/418 (48.09%), Query Frame = 2
Query: 2 MDIRKDDTERAVNLLKFYXXXXXXXXXXXXXXAMEKLIDTLETPLFSALLDIQEFYEVSL---SSAISGNK--SPVQPVYNDIIPEAKLEVQETPVXXXXXXXXXXXXXXXXXXXXXXXIASPKPVSKVKSNDNYEPEDYP--DYQDPNYNQE-------YEPEANLEDENN--------------------PWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
M +RK DT+RA++LL+ Y+SKL+++E++ L+ ++E++I+ ++ LF AL+DIQEFYEV+L I +K P+QPV E+ P ++ P +S Y+ ED P ++ P E + E NL + N + Y +I L +G G GF++AGG + PH D+ IF+TKIIT GAA DGRL+++D I+ VN+V++ VTH AV+ LK AG + L ++R K P E + E+ LIK GLG SI GG + D+ I ++K+ GG A DG+LQ+GD +L V++ L VTHEEAV LKNT V L +A+
Sbjct: 1 MPVRKQDTQRALHLLEEYRSKLSQTEDRQLRSSIERVINIFQSNLFQALIDIQEFYEVTLLDNPKCIDRSKPSEPIQPVNT-------WEISSLPSSTVTSETL------------------PSSLSPSVEKYRYQDEDTPPQEHISPQITNEVIGPELVHVSEKNLSEIENVHGFVSHSHISPIKVNGTDADYEYEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEVDVRDVTHSKAVEALKEAGSIVRLYVKRRK-------------------------PVSE--------------KIMEIKLIK-GPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNNVCLEEVTHEEAVTALKNTSDFVYLKVAK 353 HSP 2 Score: 96.2857 bits (238), Expect = 1.515e-20 Identity = 83/235 (35.32%), Postives = 120/235 (51.06%), Query Frame = 2
Query: 488 FQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRR-----LKDEYVANETTNLHE------------VVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTL 1141
+I L KG KG GF++AGG H GDN I+VTKII GAA DG+L+I D +++VN+V LE VTHE AV LKN + L + + + D Y + TN + Q + YSP + +++ ++ ++ R + GLG +I GG E+ I IS + GG AD+ G L+ GD I+ V+ L +HE+A LKN G+ VT+
Sbjct: 267 MEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNNVCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMYMNDGYAPPDITNSSSQPVDNHVSPSSFLGQTPASPARYSPVSKAVL-----GDDEITREPRKVVLHRGSTGLGFNIVGG------EDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVTI 490
BLAST of Disks large homolog 1 vs. Ensembl Human
Match: DLG1 (discs large MAGUK scaffold protein 1 [Source:HGNC Symbol;Acc:HGNC:2900]) HSP 1 Score: 147.517 bits (371), Expect = 1.704e-37 Identity = 136/418 (32.54%), Postives = 201/418 (48.09%), Query Frame = 2
Query: 2 MDIRKDDTERAVNLLKFYXXXXXXXXXXXXXXAMEKLIDTLETPLFSALLDIQEFYEVSL---SSAISGNK--SPVQPVYNDIIPEAKLEVQETPVXXXXXXXXXXXXXXXXXXXXXXXIASPKPVSKVKSNDNYEPEDYP--DYQDPNYNQE-------YEPEANLEDENN--------------------PWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
M +RK DT+RA++LL+ Y+SKL+++E++ L+ ++E++I+ ++ LF AL+DIQEFYEV+L I +K P+QPV E+ P ++ P +S Y+ ED P ++ P E + E NL + N + Y +I L +G G GF++AGG + PH D+ IF+TKIIT GAA DGRL+++D I+ VN+V++ VTH AV+ LK AG + L ++R K P E + E+ LIK GLG SI GG + D+ I ++K+ GG A DG+LQ+GD +L V++ L VTHEEAV LKNT V L +A+
Sbjct: 1 MPVRKQDTQRALHLLEEYRSKLSQTEDRQLRSSIERVINIFQSNLFQALIDIQEFYEVTLLDNPKCIDRSKPSEPIQPVNT-------WEISSLPSSTVTSETL------------------PSSLSPSVEKYRYQDEDTPPQEHISPQITNEVIGPELVHVSEKNLSEIENVHGFVSHSHISPIKVNGTDADYEYEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEVDVRDVTHSKAVEALKEAGSIVRLYVKRRK-------------------------PVSE--------------KIMEIKLIK-GPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNNVCLEEVTHEEAVTALKNTSDFVYLKVAK 353 HSP 2 Score: 96.2857 bits (238), Expect = 1.451e-20 Identity = 83/235 (35.32%), Postives = 120/235 (51.06%), Query Frame = 2
Query: 488 FQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRR-----LKDEYVANETTNLHE------------VVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTL 1141
+I L KG KG GF++AGG H GDN I+VTKII GAA DG+L+I D +++VN+V LE VTHE AV LKN + L + + + D Y + TN + Q + YSP + +++ ++ ++ R + GLG +I GG E+ I IS + GG AD+ G L+ GD I+ V+ L +HE+A LKN G+ VT+
Sbjct: 267 MEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNNVCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMYMNDGYAPPDITNSSSQPVDNHVSPSSFLGQTPASPARYSPVSKAVL-----GDDEITREPRKVVLHRGSTGLGFNIVGG------EDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVTI 490
BLAST of Disks large homolog 1 vs. Ensembl Celegans
Match: dlg-1 (Disks large homolog 1 [Source:UniProtKB/Swiss-Prot;Acc:G5ECY0]) HSP 1 Score: 124.405 bits (311), Expect = 3.344e-30 Identity = 93/256 (36.33%), Postives = 128/256 (50.00%), Query Frame = 2
Query: 458 LEDENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEY-------VANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTG-------------------GLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFI 1147
++D W I L KG G GF++ GG ++P +GD I+VT II GAA DGR++ +D+I +VN+ N E V HE AV+ LK++G + L ++R KDE T+ L V TP+ + +H S +L + S G GLG SI GG + + D+ I ++K+ G A++DGRL+VGD IL VD SL THE AVN LKNTG V L I
Sbjct: 191 IDDHGRKWELENIVLEKGHTGLGFSITGGMDQPTEDGDTSIYVTNIIEGGAALADGRMRKNDIITAVNNTNCENVKHEVAVNALKSSGNVVSLSLKRRKDEAFLPIGGNFGGSTSYLRSGV--TPSVSAGNLQHAIHSPSAPIHPPPPPPVHHGSLSQLSVGQYRSTRPNTSVIDLVKGARGLGFSIAGGQGNEHVKGDTDIYVTKIIEEGAAELDGRLRVGDKILEVDHHSLINTTHENAVNVLKNTGNRVRLLI 444 HSP 2 Score: 113.62 bits (283), Expect = 1.501e-26 Identity = 85/238 (35.71%), Postives = 120/238 (50.42%), Query Frame = 2
Query: 494 IDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQE--------------------SYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFI 1147
IDL KG +G GF++AGG H +GD I+VTKII EGAAE+DGRL++ D I+ V+ +L THE AV+ LKN G + L+I++ + + Q P T P Q+ SY + + V L+K GLG +I GG E++ I IS + PGGVAD+ G ++ GD++L V+ L TH+EA L+N G V L +
Sbjct: 362 IDLVKGARGLGFSIAGGQGNEHVKGDTDIYVTKIIEEGAAELDGRLRVGDKILEVDHHSLINTTHENAVNVLKNTGNRVRLLIQQGTGAIFNDSASQ-----QFMPTTPILRPSSVQDYNRSQMGSQSHLSYGGPLNTSYSSQAPIAIPLEPRPVQLVK-GQNGLGFNIVGG------EDNEPIYISFVLPGGVADLSGNVKTGDVLLEVNGVVLRNATHKEAAEALRNAGNPVYLTL 587 HSP 3 Score: 63.1586 bits (152), Expect = 2.481e-10 Identity = 32/89 (35.96%), Postives = 52/89 (58.43%), Query Frame = 2
Query: 887 QFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
+ E ++++ GLG SI GG D + D+ I ++ + GG A DGR++ D+I V++ + V HE AVN LK++G V+L + R
Sbjct: 199 ELENIVLEKGHTGLGFSITGGMDQPTEDGDTSIYVTNIIEGGAALADGRMRKNDIITAVNNTNCENVKHEVAVNALKSSGNVVSLSLKR 287
BLAST of Disks large homolog 1 vs. Ensembl Celegans
Match: dlg-1 (Disks large homolog 1 [Source:UniProtKB/Swiss-Prot;Acc:G5ECY0]) HSP 1 Score: 110.153 bits (274), Expect = 2.595e-26 Identity = 86/245 (35.10%), Postives = 121/245 (49.39%), Query Frame = 2
Query: 458 LEDENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEY-------VANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTG-------------------GLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFL 1114
++D W I L KG G GF++ GG ++P +GD I+VT II GAA DGR++ +D+I +VN+ N E V HE AV+ LK++G + L ++R KDE T+ L V TP+ + +H S +L + S G GLG SI GG + + D+ I ++K+ G A++DGRL+VGD IL VD SL THE AVN L
Sbjct: 145 IDDHGRKWELENIVLEKGHTGLGFSITGGMDQPTEDGDTSIYVTNIIEGGAALADGRMRKNDIITAVNNTNCENVKHEVAVNALKSSGNVVSLSLKRRKDEAFLPIGGNFGGSTSYLRSGV--TPSVSAGNLQHAIHSPSAPIHPPPPPPVHHGSLSQLSVGQYRSTRPNTSVIDLVKGARGLGFSIAGGQGNEHVKGDTDIYVTKIIEEGAAELDGRLRVGDKILEVDHHSLINTTHENAVNVL 387 HSP 2 Score: 61.2326 bits (147), Expect = 5.150e-10 Identity = 32/89 (35.96%), Postives = 52/89 (58.43%), Query Frame = 2
Query: 887 QFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
+ E ++++ GLG SI GG D + D+ I ++ + GG A DGR++ D+I V++ + V HE AVN LK++G V+L + R
Sbjct: 153 ELENIVLEKGHTGLGFSITGGMDQPTEDGDTSIYVTNIIEGGAALADGRMRKNDIITAVNNTNCENVKHEVAVNALKSSGNVVSLSLKR 241
BLAST of Disks large homolog 1 vs. Ensembl Celegans
Match: dlg-1 (Disks large homolog 1 [Source:UniProtKB/Swiss-Prot;Acc:G5ECY0]) HSP 1 Score: 110.153 bits (274), Expect = 2.595e-26 Identity = 86/245 (35.10%), Postives = 121/245 (49.39%), Query Frame = 2
Query: 458 LEDENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEY-------VANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTG-------------------GLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFL 1114
++D W I L KG G GF++ GG ++P +GD I+VT II GAA DGR++ +D+I +VN+ N E V HE AV+ LK++G + L ++R KDE T+ L V TP+ + +H S +L + S G GLG SI GG + + D+ I ++K+ G A++DGRL+VGD IL VD SL THE AVN L
Sbjct: 145 IDDHGRKWELENIVLEKGHTGLGFSITGGMDQPTEDGDTSIYVTNIIEGGAALADGRMRKNDIITAVNNTNCENVKHEVAVNALKSSGNVVSLSLKRRKDEAFLPIGGNFGGSTSYLRSGV--TPSVSAGNLQHAIHSPSAPIHPPPPPPVHHGSLSQLSVGQYRSTRPNTSVIDLVKGARGLGFSIAGGQGNEHVKGDTDIYVTKIIEEGAAELDGRLRVGDKILEVDHHSLINTTHENAVNVL 387 HSP 2 Score: 61.2326 bits (147), Expect = 5.150e-10 Identity = 32/89 (35.96%), Postives = 52/89 (58.43%), Query Frame = 2
Query: 887 QFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
+ E ++++ GLG SI GG D + D+ I ++ + GG A DGR++ D+I V++ + V HE AVN LK++G V+L + R
Sbjct: 153 ELENIVLEKGHTGLGFSITGGMDQPTEDGDTSIYVTNIIEGGAALADGRMRKNDIITAVNNTNCENVKHEVAVNALKSSGNVVSLSLKR 241
BLAST of Disks large homolog 1 vs. Ensembl Celegans
Match: mpz-1 (Multiple PDZ domain protein [Source:UniProtKB/TrEMBL;Acc:G1K0W2]) HSP 1 Score: 72.0182 bits (175), Expect = 2.326e-13 Identity = 69/250 (27.60%), Postives = 111/250 (44.40%), Query Frame = 2
Query: 407 PDYQDPNYNQEYEPEANLEDENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIARF 1156
P+ ++ + + + E EN +ID K KG G ++ GG + + + ++ ++GAA DGRLK D ++ VN +L VTH+ ++ L+ + L+I R N +L + Q + FE+ L+K++ GLGISI G NE Y+S ++ GG+A+ DGRL GD IL V+ K + G E+ LK V L + R+
Sbjct: 13 PNQEELSRKKSFSQERTQAIENGRETMIEID--KDGKGLGLSIVGGADTVL----GTVVIHEVYSDGAAAHDGRLKPGDQVLEVNGTSLRGVTHDQSIAYLRRTPPKVRLLIYR-----DVNLQLSLLDPTQI-------------------------YNIFEIDLVKKTGRGLGISIVG----RKNEPGVYVS--EIVKGGLAESDGRLMTGDQILEVNGKDVRGCMQEDVAAMLKTITGKVHLKLGRW 220 HSP 2 Score: 54.6842 bits (130), Expect = 7.636e-8 Identity = 38/117 (32.48%), Postives = 59/117 (50.43%), Query Frame = 2
Query: 803 ATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
A PN S ++S+ +E + + + I + GLG+SI GG D + I ++ G A DGRL+ GD +L V+ SL GVTH++++ +L+ T V L I R
Sbjct: 11 AAPNQEELS---RKKSFSQERTQAIENGRETMIEIDKDGKGLGLSIVGGADTVLG----TVVIHEVYSDGAAAHDGRLKPGDQVLEVNGTSLRGVTHDQSIAYLRRTPPKVRLLIYR 120
BLAST of Disks large homolog 1 vs. Ensembl Celegans
Match: mpz-1 (Multiple PDZ domain protein [Source:UniProtKB/TrEMBL;Acc:G1K0W2]) HSP 1 Score: 72.4034 bits (176), Expect = 3.157e-13 Identity = 69/250 (27.60%), Postives = 111/250 (44.40%), Query Frame = 2
Query: 407 PDYQDPNYNQEYEPEANLEDENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIARF 1156
P+ ++ + + + E EN +ID K KG G ++ GG + + + ++ ++GAA DGRLK D ++ VN +L VTH+ ++ L+ + L+I R N +L + Q + FE+ L+K++ GLGISI G NE Y+S ++ GG+A+ DGRL GD IL V+ K + G E+ LK V L + R+
Sbjct: 523 PNQEELSRKKSFSQERTQAIENGRETMIEID--KDGKGLGLSIVGGADTVL----GTVVIHEVYSDGAAAHDGRLKPGDQVLEVNGTSLRGVTHDQSIAYLRRTPPKVRLLIYR-----DVNLQLSLLDPTQI-------------------------YNIFEIDLVKKTGRGLGISIVG----RKNEPGVYVS--EIVKGGLAESDGRLMTGDQILEVNGKDVRGCMQEDVAAMLKTITGKVHLKLGRW 730 HSP 2 Score: 55.4546 bits (132), Expect = 6.869e-8 Identity = 38/117 (32.48%), Postives = 59/117 (50.43%), Query Frame = 2
Query: 803 ATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
A PN S ++S+ +E + + + I + GLG+SI GG D + I ++ G A DGRL+ GD +L V+ SL GVTH++++ +L+ T V L I R
Sbjct: 521 AAPNQEELS---RKKSFSQERTQAIENGRETMIEIDKDGKGLGLSIVGGADTVLG----TVVIHEVYSDGAAAHDGRLKPGDQVLEVNGTSLRGVTHDQSIAYLRRTPPKVRLLIYR 630
BLAST of Disks large homolog 1 vs. Ensembl Fly
Match: dlg1 (gene:FBgn0001624 transcript:FBtr0073484) HSP 1 Score: 117.472 bits (293), Expect = 7.881e-28 Identity = 88/232 (37.93%), Postives = 125/232 (53.88%), Query Frame = 2
Query: 470 NNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHV----DDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
++ WLY I L +G G GF++AGG + PH D I++TK+I+ GAA DGRL I+D+IVSVNDV++ V H +AVD LK AG + L ++R + TP G + + ++ + E+ L+K GLG SI GG + D+ I ++KL GG A VDGRL +GD ++ V +K+L VTHE AV LK+ VTL I +
Sbjct: 506 DDSWLYEDIQLERGNSGLGFSIAGGTDNPHIGTDTSIYITKLISGGAAAADGRLSINDIIVSVNDVSVVDVPHASAVDALKKAGNVVKLHVKRKRG-------------TATTPAAGSAAGDA-------RDSAASGPKVIEIDLVK-GGKGLGFSIAGGIGNQHIPGDNGIYVTKLMDGGAAQVDGRLSIGDKLIAVRTNGSEKNLENVTHELAVATLKSITDKVTLIIGK 716
BLAST of Disks large homolog 1 vs. Ensembl Fly
Match: dlg1 (gene:FBgn0001624 transcript:FBtr0301288) HSP 1 Score: 117.087 bits (292), Expect = 1.490e-27 Identity = 88/232 (37.93%), Postives = 125/232 (53.88%), Query Frame = 2
Query: 470 NNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHV----DDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
++ WLY I L +G G GF++AGG + PH D I++TK+I+ GAA DGRL I+D+IVSVNDV++ V H +AVD LK AG + L ++R + TP G + + ++ + E+ L+K GLG SI GG + D+ I ++KL GG A VDGRL +GD ++ V +K+L VTHE AV LK+ VTL I +
Sbjct: 447 DDSWLYEDIQLERGNSGLGFSIAGGTDNPHIGTDTSIYITKLISGGAAAADGRLSINDIIVSVNDVSVVDVPHASAVDALKKAGNVVKLHVKRKRG-------------TATTPAAGSAAGD-------ARDSAASGPKVIEIDLVK-GGKGLGFSIAGGIGNQHIPGDNGIYVTKLMDGGAAQVDGRLSIGDKLIAVRTNGSEKNLENVTHELAVATLKSITDKVTLIIGK 657 HSP 2 Score: 50.447 bits (119), Expect = 2.930e-6 Identity = 31/80 (38.75%), Postives = 44/80 (55.00%), Query Frame = 2
Query: 905 IKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLF 1144
I++ GLG +I GG E+ I +S + GG AD+ L+ GD +L V++ +L THEEA LK +G VTL
Sbjct: 747 IQKGPQGLGFNIVGG------EDGQGIYVSFILAGGPADLGSELKRGDQLLSVNNVNLTHATHEEAAQALKTSGGVVTLL 820
BLAST of Disks large homolog 1 vs. Ensembl Fly
Match: dlg1 (gene:FBgn0001624 transcript:FBtr0308088) HSP 1 Score: 116.316 bits (290), Expect = 2.098e-27 Identity = 88/232 (37.93%), Postives = 125/232 (53.88%), Query Frame = 2
Query: 470 NNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHV----DDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
++ WLY I L +G G GF++AGG + PH D I++TK+I+ GAA DGRL I+D+IVSVNDV++ V H +AVD LK AG + L ++R + TP G + + ++ + E+ L+K GLG SI GG + D+ I ++KL GG A VDGRL +GD ++ V +K+L VTHE AV LK+ VTL I +
Sbjct: 41 DDSWLYEDIQLERGNSGLGFSIAGGTDNPHIGTDTSIYITKLISGGAAAADGRLSINDIIVSVNDVSVVDVPHASAVDALKKAGNVVKLHVKRKRG-------------TATTPAAGSAAGD-------ARDSAASGPKVIEIDLVKGGK-GLGFSIAGGIGNQHIPGDNGIYVTKLMDGGAAQVDGRLSIGDKLIAVRTNGSEKNLENVTHELAVATLKSITDKVTLIIGK 251 HSP 2 Score: 50.447 bits (119), Expect = 2.683e-6 Identity = 31/80 (38.75%), Postives = 44/80 (55.00%), Query Frame = 2
Query: 905 IKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLF 1144
I++ GLG +I GG E+ I +S + GG AD+ L+ GD +L V++ +L THEEA LK +G VTL
Sbjct: 497 IQKGPQGLGFNIVGG------EDGQGIYVSFILAGGPADLGSELKRGDQLLSVNNVNLTHATHEEAAQALKTSGGVVTLL 570
BLAST of Disks large homolog 1 vs. Ensembl Fly
Match: dlg1 (gene:FBgn0001624 transcript:FBtr0330390) HSP 1 Score: 116.316 bits (290), Expect = 2.177e-27 Identity = 91/239 (38.08%), Postives = 128/239 (53.56%), Query Frame = 2
Query: 455 NLEDEN--NPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHV----DDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
NL+ N + WLY I L +G G GF++AGG + PH D I++TK+I+ GAA DGRL I+D+IVSVNDV++ V H +AVD LK AG + L ++R + TP G + + ++ + E+ L+K GLG SI GG + D+ I ++KL GG A VDGRL +GD ++ V +K+L VTHE AV LK+ VTL I +
Sbjct: 26 NLDSVNGDDSWLYEDIQLERGNSGLGFSIAGGTDNPHIGTDTSIYITKLISGGAAAADGRLSINDIIVSVNDVSVVDVPHASAVDALKKAGNVVKLHVKRKRG-------------TATTPAAGSAAGD-------ARDSAASGPKVIEIDLVKGGK-GLGFSIAGGIGNQHIPGDNGIYVTKLMDGGAAQVDGRLSIGDKLIAVRTNGSEKNLENVTHELAVATLKSITDKVTLIIGK 243 HSP 2 Score: 59.3066 bits (142), Expect = 5.756e-9 Identity = 38/101 (37.62%), Postives = 56/101 (55.45%), Query Frame = 2
Query: 851 YHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
++ ++ D+ +E ++R GLG SI GG D + D+ I I+KL GG A DGRL + D+I+ V+D S+ V H AV+ LK G V L + R
Sbjct: 25 FNLDSVNGDDSWLYEDIQLERGNSGLGFSIAGGTDNPHIGTDTSIYITKLISGGAAAADGRLSINDIIVSVNDVSVVDVPHASAVDALKKAGNVVKLHVKR 125 HSP 3 Score: 50.8322 bits (120), Expect = 2.625e-6 Identity = 31/80 (38.75%), Postives = 44/80 (55.00%), Query Frame = 2
Query: 905 IKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLF 1144
I++ GLG +I GG E+ I +S + GG AD+ L+ GD +L V++ +L THEEA LK +G VTL
Sbjct: 489 IQKGPQGLGFNIVGG------EDGQGIYVSFILAGGPADLGSELKRGDQLLSVNNVNLTHATHEEAAQALKTSGGVVTLL 562
BLAST of Disks large homolog 1 vs. Ensembl Fly
Match: dlg1 (gene:FBgn0001624 transcript:FBtr0073485) HSP 1 Score: 116.316 bits (290), Expect = 2.189e-27 Identity = 91/239 (38.08%), Postives = 128/239 (53.56%), Query Frame = 2
Query: 455 NLEDEN--NPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHV----DDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
NL+ N + WLY I L +G G GF++AGG + PH D I++TK+I+ GAA DGRL I+D+IVSVNDV++ V H +AVD LK AG + L ++R + TP G + + ++ + E+ L+K GLG SI GG + D+ I ++KL GG A VDGRL +GD ++ V +K+L VTHE AV LK+ VTL I +
Sbjct: 26 NLDSVNGDDSWLYEDIQLERGNSGLGFSIAGGTDNPHIGTDTSIYITKLISGGAAAADGRLSINDIIVSVNDVSVVDVPHASAVDALKKAGNVVKLHVKRKRG-------------TATTPAAGSAAGD-------ARDSAASGPKVIEIDLVKGGK-GLGFSIAGGIGNQHIPGDNGIYVTKLMDGGAAQVDGRLSIGDKLIAVRTNGSEKNLENVTHELAVATLKSITDKVTLIIGK 243 HSP 2 Score: 58.9214 bits (141), Expect = 6.536e-9 Identity = 38/101 (37.62%), Postives = 56/101 (55.45%), Query Frame = 2
Query: 851 YHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
++ ++ D+ +E ++R GLG SI GG D + D+ I I+KL GG A DGRL + D+I+ V+D S+ V H AV+ LK G V L + R
Sbjct: 25 FNLDSVNGDDSWLYEDIQLERGNSGLGFSIAGGTDNPHIGTDTSIYITKLISGGAAAADGRLSINDIIVSVNDVSVVDVPHASAVDALKKAGNVVKLHVKR 125 HSP 3 Score: 50.447 bits (119), Expect = 2.786e-6 Identity = 31/80 (38.75%), Postives = 44/80 (55.00%), Query Frame = 2
Query: 905 IKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLF 1144
I++ GLG +I GG E+ I +S + GG AD+ L+ GD +L V++ +L THEEA LK +G VTL
Sbjct: 489 IQKGPQGLGFNIVGG------EDGQGIYVSFILAGGPADLGSELKRGDQLLSVNNVNLTHATHEEAAQALKTSGGVVTLL 562
BLAST of Disks large homolog 1 vs. Ensembl Zebrafish
Match: dlg3 (discs, large homolog 3 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-050208-93]) HSP 1 Score: 119.398 bits (298), Expect = 2.977e-28 Identity = 88/223 (39.46%), Postives = 115/223 (51.57%), Query Frame = 2
Query: 485 YFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
Y +I L +G G GF++AGG + PH D GIF+TKII GAA +DGRL ++D ++ VNDV++ V H AV+ LK AG + L++RR QA P T EV L+K GLG SI GG + D+ I I+K+ GG A DGRLQ GD +L V++ L V HEEAV LKNT V L +A+
Sbjct: 148 YEEIILERGNSGLGFSIAGGMDNPHIPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNDVDVSEVVHSKAVEALKEAGPVVRLLVRRR----------------QAPPET-----------------------ILEVNLLK-GPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQTGDRLLAVNNIILQDVRHEEAVAALKNTSDMVYLKVAK 330 HSP 2 Score: 106.686 bits (265), Expect = 4.851e-24 Identity = 83/251 (33.07%), Postives = 124/251 (49.40%), Query Frame = 2
Query: 476 PWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRR-----LKDEYV---------------ANETTNLHEVVQATPNTGYYSPEHEQESY----HEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIARF 1156
P +++L KG KG GF++AGG H GDN I++TKII GAA+ DGRL+ D +++VN++ L+ V HE AV LKN + L + + L D Y +++ + P Y P+ Y E D ++ L+ + + GLG +I GG E+ I +S + GG AD+ G L+ GD IL V+ +L THE+A LK G+TVT+ IA++
Sbjct: 240 PETILEVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQTGDRLLAVNNIILQDVRHEEAVAALKNTSDMVYLKVAKPGPVHLNDMYAPPDYSSTFPTMVDNHVGHNSSMAYMGGMEPKPVYQPPQVTPSRYSPVPRHMLGEEDFTREPRKILLHKGSTGLGFNIVGG------EDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQTVTI-IAQY 483 HSP 3 Score: 76.2554 bits (186), Expect = 2.573e-14 Identity = 38/94 (40.43%), Postives = 55/94 (58.51%), Query Frame = 2
Query: 872 NDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
+D ++E +++R GLG SI GG D + +D I I+K+ PGG A +DGRL V D +L V+D ++ V H +AV LK G V L + R
Sbjct: 142 SDGMYKYEEIILERGNSGLGFSIAGGMDNPHIPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNDVDVSEVVHSKAVEALKEAGPVVRLLVRR 235 HSP 4 Score: 53.9138 bits (128), Expect = 2.895e-7 Identity = 59/181 (32.60%), Postives = 80/181 (44.20%), Query Frame = 2
Query: 344 IASPKPVSKVKSNDNYEPEDY---------------------------PDYQDPNYN-QEYEPEAN--LEDENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEV 796
+A P PV ND Y P DY P YQ P Y P L +E+ +I L+KG G GF + GG E GIFV+ I+ G A++ G L+ D I+SVN VNL THE A LK AGQ++ +I + +EY E + +H++
Sbjct: 328 VAKPGPVH---LNDMYAPPDYSSTFPTMVDNHVGHNSSMAYMGGMEPKPVYQPPQVTPSRYSPVPRHMLGEEDFTREPRKILLHKGSTGLGFNIVGG------EDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQTVTIIAQYRPEEYSRFE-SKIHDL 498
BLAST of Disks large homolog 1 vs. Ensembl Zebrafish
Match: dlg3 (discs, large homolog 3 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-050208-93]) HSP 1 Score: 119.398 bits (298), Expect = 3.035e-28 Identity = 88/223 (39.46%), Postives = 115/223 (51.57%), Query Frame = 2
Query: 485 YFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
Y +I L +G G GF++AGG + PH D GIF+TKII GAA +DGRL ++D ++ VNDV++ V H AV+ LK AG + L++RR QA P T EV L+K GLG SI GG + D+ I I+K+ GG A DGRLQ GD +L V++ L V HEEAV LKNT V L +A+
Sbjct: 148 YEEIILERGNSGLGFSIAGGMDNPHIPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNDVDVSEVVHSKAVEALKEAGPVVRLLVRRR----------------QAPPET-----------------------ILEVNLLK-GPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQTGDRLLAVNNIILQDVRHEEAVAALKNTSDMVYLKVAK 330 HSP 2 Score: 104.375 bits (259), Expect = 2.800e-23 Identity = 83/257 (32.30%), Postives = 124/257 (48.25%), Query Frame = 2
Query: 476 PWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRR-----LKDEYV---------------------ANETTNLHEVVQATPNTGYYSPEHEQESY----HEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIARF 1156
P +++L KG KG GF++AGG H GDN I++TKII GAA+ DGRL+ D +++VN++ L+ V HE AV LKN + L + + L D Y +++ + P Y P+ Y E D ++ L+ + + GLG +I GG E+ I +S + GG AD+ G L+ GD IL V+ +L THE+A LK G+TVT+ IA++
Sbjct: 240 PETILEVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQTGDRLLAVNNIILQDVRHEEAVAALKNTSDMVYLKVAKPGPVHLNDMYAPPDYSSSLGLPPAFPTMVDNHVGHNSSMAYMGGMEPKPVYQPPQVTPSRYSPVPRHMLGEEDFTREPRKILLHKGSTGLGFNIVGG------EDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQTVTI-IAQY 489 HSP 3 Score: 76.2554 bits (186), Expect = 2.568e-14 Identity = 38/94 (40.43%), Postives = 55/94 (58.51%), Query Frame = 2
Query: 872 NDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
+D ++E +++R GLG SI GG D + +D I I+K+ PGG A +DGRL V D +L V+D ++ V H +AV LK G V L + R
Sbjct: 142 SDGMYKYEEIILERGNSGLGFSIAGGMDNPHIPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNDVDVSEVVHSKAVEALKEAGPVVRLLVRR 235 HSP 4 Score: 53.9138 bits (128), Expect = 3.488e-7 Identity = 50/136 (36.76%), Postives = 70/136 (51.47%), Query Frame = 2
Query: 398 EDYPDYQDPNYN-QEYEPEAN--LEDENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEV 796
E P YQ P Y P L +E+ +I L+KG G GF + GG E GIFV+ I+ G A++ G L+ D I+SVN VNL THE A LK AGQ++ +I + +EY E + +H++
Sbjct: 376 EPKPVYQPPQVTPSRYSPVPRHMLGEEDFTREPRKILLHKGSTGLGFNIVGG------EDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQTVTIIAQYRPEEYSRFE-SKIHDL 504
BLAST of Disks large homolog 1 vs. Ensembl Zebrafish
Match: dlg3 (discs, large homolog 3 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-050208-93]) HSP 1 Score: 119.398 bits (298), Expect = 3.104e-28 Identity = 88/223 (39.46%), Postives = 115/223 (51.57%), Query Frame = 2
Query: 485 YFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
Y +I L +G G GF++AGG + PH D GIF+TKII GAA +DGRL ++D ++ VNDV++ V H AV+ LK AG + L++RR QA P T EV L+K GLG SI GG + D+ I I+K+ GG A DGRLQ GD +L V++ L V HEEAV LKNT V L +A+
Sbjct: 130 YEEIILERGNSGLGFSIAGGMDNPHIPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNDVDVSEVVHSKAVEALKEAGPVVRLLVRRR----------------QAPPET-----------------------ILEVNLLK-GPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQTGDRLLAVNNIILQDVRHEEAVAALKNTSDMVYLKVAK 312 HSP 2 Score: 104.375 bits (259), Expect = 2.666e-23 Identity = 83/257 (32.30%), Postives = 124/257 (48.25%), Query Frame = 2
Query: 476 PWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRR-----LKDEYV---------------------ANETTNLHEVVQATPNTGYYSPEHEQESY----HEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIARF 1156
P +++L KG KG GF++AGG H GDN I++TKII GAA+ DGRL+ D +++VN++ L+ V HE AV LKN + L + + L D Y +++ + P Y P+ Y E D ++ L+ + + GLG +I GG E+ I +S + GG AD+ G L+ GD IL V+ +L THE+A LK G+TVT+ IA++
Sbjct: 222 PETILEVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQTGDRLLAVNNIILQDVRHEEAVAALKNTSDMVYLKVAKPGPVHLNDMYAPPDYSSSLGLPPAFPTMVDNHVGHNSSMAYMGGMEPKPVYQPPQVTPSRYSPVPRHMLGEEDFTREPRKILLHKGSTGLGFNIVGG------EDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQTVTI-IAQY 471 HSP 3 Score: 76.2554 bits (186), Expect = 2.588e-14 Identity = 38/101 (37.62%), Postives = 59/101 (58.42%), Query Frame = 2
Query: 851 YHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
++++ +D ++E +++R GLG SI GG D + +D I I+K+ PGG A +DGRL V D +L V+D ++ V H +AV LK G V L + R
Sbjct: 117 WYDQVNGSDGMYKYEEIILERGNSGLGFSIAGGMDNPHIPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNDVDVSEVVHSKAVEALKEAGPVVRLLVRR 217 HSP 4 Score: 53.9138 bits (128), Expect = 3.378e-7 Identity = 50/136 (36.76%), Postives = 70/136 (51.47%), Query Frame = 2
Query: 398 EDYPDYQDPNYN-QEYEP--EANLEDENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEV 796
E P YQ P Y P L +E+ +I L+KG G GF + GG E GIFV+ I+ G A++ G L+ D I+SVN VNL THE A LK AGQ++ +I + +EY E + +H++
Sbjct: 358 EPKPVYQPPQVTPSRYSPVPRHMLGEEDFTREPRKILLHKGSTGLGFNIVGG------EDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQTVTIIAQYRPEEYSRFE-SKIHDL 486
BLAST of Disks large homolog 1 vs. Ensembl Zebrafish
Match: dlg1l (discs, large (Drosophila) homolog 1, like [Source:NCBI gene;Acc:497648]) HSP 1 Score: 117.857 bits (294), Expect = 6.290e-28 Identity = 87/237 (36.71%), Postives = 124/237 (52.32%), Query Frame = 2
Query: 488 FQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRR-----LKDEYVANETTNLHE------------VVQATP--NTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTL 1141
+I L KG KG GF++AGG H GDN I+VTKII GAA DGRL+I D +++VN LE VTHE AV LKN + L + + + D + + TN + + Q P ++G +SP + ++D ++ ++ R T GLG +I GG E+ I IS + GG AD+ G L+ GD ++ V+ L G THE+A LKN G+TVT+
Sbjct: 247 MEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKLLAVNSSCLEEVTHEHAVTALKNTPDVVYLKVAKPNSVFMNDSFAPPDITNSYSQHMENHISPPSYLSQPLPPVHSGRFSPTPKTTV-----GDDDVTREPRKVVLHRGTTGLGFNIVGG------EDGEGIFISFILAGGPADLCGELRKGDRLVSVNGIDLRGATHEQAAAALKNAGQTVTI 472 HSP 2 Score: 117.087 bits (292), Expect = 1.161e-27 Identity = 86/223 (38.57%), Postives = 116/223 (52.02%), Query Frame = 2
Query: 485 YFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
Y +I L +G G GF++AGG + PH D IF+TK+I GAA DGRL+++DVI+ VN+V++ VTH AV+ LK AG + L +RR K A+E + E+ LIK GLG SI GG + D+ I ++K+ GG A DGRLQ+GD +L V+ L VTHE AV LKNT V L +A+
Sbjct: 151 YEEITLERGNSGLGFSIAGGTDNPHIGEDPSIFITKVIPGGAAAQDGRLRVNDVILRVNEVDVRDVTHSKAVEALKEAGSLVRLYVRRRKS---ASE------------------------------------KVMEIKLIK-GPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKLLAVNSSCLEEVTHEHAVTALKNTPDVVYLKVAK 333 HSP 3 Score: 77.0258 bits (188), Expect = 1.562e-14 Identity = 43/97 (44.33%), Postives = 58/97 (59.79%), Query Frame = 2
Query: 863 NAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
N +F+ E+TL +R GLG SI GG D + ED I I+K+ PGG A DGRL+V D+IL V++ + VTH +AV LK G V L++ R
Sbjct: 143 NGTEADFEYEEITL-ERGNSGLGFSIAGGTDNPHIGEDPSIFITKVIPGGAAAQDGRLRVNDVILRVNEVDVRDVTHSKAVEALKEAGSLVRLYVRR 238 HSP 4 Score: 52.373 bits (124), Expect = 7.657e-7 Identity = 36/106 (33.96%), Postives = 60/106 (56.60%), Query Frame = 2
Query: 446 PEANLEDENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEY 763
P+ + D++ ++ L++G G GF + GG E GIF++ I+ G A++ G L+ D +VSVN ++L THE A LKNAGQ++ ++ + +EY
Sbjct: 382 PKTTVGDDDVTREPRKVVLHRGTTGLGFNIVGG------EDGEGIFISFILAGGPADLCGELRKGDRLVSVNGIDLRGATHEQAAAALKNAGQTVTIVAQYRPEEY 481
BLAST of Disks large homolog 1 vs. Ensembl Zebrafish
Match: dlg2 (discs, large homolog 2 (Drosophila) [Source:NCBI gene;Acc:497638]) HSP 1 Score: 117.857 bits (294), Expect = 8.493e-28 Identity = 84/223 (37.67%), Postives = 116/223 (52.02%), Query Frame = 2
Query: 485 YFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
+ +I L +G G GF++AGG + PH D GIF+TKII GAA DGRL+++D I+ VN+ ++ V+H AV+ LK AG + L +RR + + E V E+ LIK GLG SI GG + D+ I ++K+ GG A DGRLQVGD +L V++ +L VTHEEAV LKNT V L + +
Sbjct: 134 FEEITLERGNSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNESDVSEVSHSKAVEALKAAGSIVRLYVRRRRP---------MLETVT------------------------------EIKLIK-GPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYTLEEVTHEEAVAILKNTSDVVYLKVGK 316 HSP 2 Score: 107.842 bits (268), Expect = 1.706e-24 Identity = 93/263 (35.36%), Postives = 127/263 (48.29%), Query Frame = 2
Query: 491 QIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRR-----LKDEYVANETTNLHEVVQATPN---------------------TGYYS--PEH--------EQESYHEENAENDNFQQFEV-----TLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIARF 1156
+I L KG KG GF++AGG H GDN I+VTKII GAA+ DGRL++ D ++ VN+ LE VTHE AV LKN + L + + L D Y + T H A N G YS P+H S E + Q F++ ++ + + GLG +I GG E+ I +S + GG AD+ G L+ GD IL V+ L G THE+A LK G+TVT+ IA++
Sbjct: 231 EIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYTLEEVTHEEAVAILKNTSDVVYLKVGKPTSVYLSDPYGPPDIT--HSFSPAMENHISSPGNNGTLEYKSSLPPISPGRYSPLPKHLLGEEDINRNPSLDEMEGHRFDSQHFQLREPRKIVLHKGSTGLGFNIVGG------EDGEGIFVSFILAGGPADLSGELRRGDQILSVNGIDLRGATHEQAAAALKGAGQTVTI-IAQY 484 HSP 3 Score: 74.3294 bits (181), Expect = 1.183e-13 Identity = 38/89 (42.70%), Postives = 54/89 (60.67%), Query Frame = 2
Query: 887 QFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
+FE ++R GLG SI GG D + +D I I+K+ PGG A DGRL+V D IL V++ ++ V+H +AV LK G V L++ R
Sbjct: 133 EFEEITLERGNSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNESDVSEVSHSKAVEALKAAGSIVRLYVRR 221 HSP 4 Score: 53.1434 bits (126), Expect = 5.133e-7 Identity = 37/91 (40.66%), Postives = 53/91 (58.24%), Query Frame = 2
Query: 491 QIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEY 763
+I L+KG G GF + GG E GIFV+ I+ G A++ G L+ D I+SVN ++L THE A LK AGQ++ +I + +EY
Sbjct: 405 KIVLHKGSTGLGFNIVGG------EDGEGIFVSFILAGGPADLSGELRRGDQILSVNGIDLRGATHEQAAAALKGAGQTVTIIAQYRPEEY 489
BLAST of Disks large homolog 1 vs. Ensembl Xenopus
Match: pinx1 (PIN2 (TERF1) interacting telomerase inhibitor 1 [Source:Xenbase;Acc:XB-GENE-951063]) HSP 1 Score: 147.517 bits (371), Expect = 1.414e-37 Identity = 133/388 (34.28%), Postives = 192/388 (49.48%), Query Frame = 2
Query: 2 MDIRKDDTERAVNLLKFYXXXXXXXXXXXXXXAMEKLIDTLETPLFSALLDIQEFYEVSL--SSAISGNKSPVQPVYNDIIPEAKLEVQETPVXXXXXXXXXXXXXXXXXXXXXXXIASPKPVSKVKSNDNYEPEDYPDYQDPNY--NQEYEPEANLEDENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
M +RK DT+RA+ LL+ Y+ KL+++E+K L+K++E++I ++ LF AL+DIQEFYEV+L + S N P +PV E T S + I PV V + N P P P N + E A + + + Y +I L +G G GF++AGG + PH D IF+TKII+ GAA DGRL+++D I+ VN+V++ VTH AV+ LK AG + L +RR K P E + ++ L+K GLG SI GG + D+ I ++K+ GG A DGRLQ+GD +L V+ L V+HE+AV LKNT V L +A+
Sbjct: 1 MPVRKQDTQRALTLLEEYRCKLHQTEDKQLRKSIERVIGIFQSNLFQALIDIQEFYEVTLLDNPKSSDNAKPTEPVQTINTWEYSSLPNSTATCETLPSSLILNVETPEADTPCPPIVPVIPVIPVPAESNVIPSSTPQANPPPVIVNTDLETPAYVNGTDAEYEYEEITLERGTSGLGFSIAGGTDNPHIGDDISIFITKIISGGAAAQDGRLRVNDCILRVNEVDVHDVTHSKAVEALKEAGSIVRLYVRRRK-------------------------PVTE--------------KIMDIKLVK-GPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKLLAVNTVCLEEVSHEDAVTALKNTSDFVNLKVAK 348 HSP 2 Score: 116.316 bits (290), Expect = 3.808e-27 Identity = 90/235 (38.30%), Postives = 122/235 (51.91%), Query Frame = 2
Query: 494 IDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRR-----LKDEYVANETTNLHEVV-------------QATPNTGYYSPEHEQESYHEENAENDNF-QQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTL 1141
I L KG KG GF++AGG H GDN I+VTKII GAA DGRL+I D +++VN V LE V+HE AV LKN + L + + + D Y + TN + P+ G YSP + E+D+ ++ +++R T GLG +I GG E+ I IS + GG AD+ G LQ GD I+ V+ L THE+A LKN G+TVT+
Sbjct: 264 IKLVKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKLLAVNTVCLEEVSHEDAVTALKNTSDFVNLKVAKPTTMYMNDNYAPPDITNSYSQQVDNHISPSGFIGHPLPPSPGRYSPAPKG------MLEDDDLTREPRKVVLQRGTTGLGFNIVGG------EDGEGIFISFILAGGPADLSGELQKGDRIMSVNGVDLKSATHEQAAAALKNAGQTVTI 486 HSP 3 Score: 55.8398 bits (133), Expect = 1.044e-7 Identity = 39/106 (36.79%), Postives = 61/106 (57.55%), Query Frame = 2
Query: 446 PEANLEDENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEY 763
P+ LED++ ++ L +G G GF + GG E GIF++ I+ G A++ G L+ D I+SVN V+L+ THE A LKNAGQ++ ++ + +EY
Sbjct: 396 PKGMLEDDDLTREPRKVVLQRGTTGLGFNIVGG------EDGEGIFISFILAGGPADLSGELQKGDRIMSVNGVDLKSATHEQAAAALKNAGQTVTIVAQYRPEEY 495
BLAST of Disks large homolog 1 vs. Ensembl Xenopus
Match: pinx1 (PIN2 (TERF1) interacting telomerase inhibitor 1 [Source:Xenbase;Acc:XB-GENE-951063]) HSP 1 Score: 122.479 bits (306), Expect = 3.190e-29 Identity = 91/230 (39.57%), Postives = 124/230 (53.91%), Query Frame = 2
Query: 494 IDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRR-----LKDEYVANETTNLHEVVQAT--------PNTGYYSPEHEQESYHEENAENDNF-QQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTL 1141
I L KG KG GF++AGG H GDN I+VTKII GAA DGRL+I D +++VN V LE V+HE AV LKN + L + + + D Y + TNL + + P+ G YSP + E+D+ ++ +++R T GLG +I GG E+ I IS + GG AD+ G LQ GD I+ V+ L THE+A LKN G+TVT+
Sbjct: 195 IKLVKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKLLAVNTVCLEEVSHEDAVTALKNTSDFVNLKVAKPTTMYMNDNYAPPDITNLDNHISPSGFIGHPLPPSPGRYSPAPKG------MLEDDDLTREPRKVVLQRGTTGLGFNIVGG------EDGEGIFISFILAGGPADLSGELQKGDRIMSVNGVDLKSATHEQAAAALKNAGQTVTI 412 HSP 2 Score: 114.39 bits (285), Expect = 1.596e-26 Identity = 90/261 (34.48%), Postives = 128/261 (49.04%), Query Frame = 2
Query: 377 SNDNYEPEDYPDYQDPNY--NQEYEPEANLEDENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
+ N P P P N + E A + + + Y +I L +G G GF++AGG + PH D IF+TKII+ GAA DGRL+++D I+ VN+V++ VTH AV+ LK AG + L +RR K P E + ++ L+K GLG SI GG + D+ I ++K+ GG A DGRLQ+GD +L V+ L V+HE+AV LKNT V L +A+
Sbjct: 59 AESNVIPSSTPQANPPPVIVNTDLETPAYVNGTDAEYEYEEITLERGTSGLGFSIAGGTDNPHIGDDISIFITKIISGGAAAQDGRLRVNDCILRVNEVDVHDVTHSKAVEALKEAGSIVRLYVRRRK-------------------------PVTE--------------KIMDIKLVK-GPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKLLAVNTVCLEEVSHEDAVTALKNTSDFVNLKVAK 279 HSP 3 Score: 56.225 bits (134), Expect = 7.321e-8 Identity = 47/142 (33.10%), Postives = 71/142 (50.00%), Query Frame = 2
Query: 380 NDNYEPEDYPDYQD------------PNYNQEYEP--EANLEDENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEY 763
NDNY P D + + P Y P + LED++ ++ L +G G GF + GG E GIF++ I+ G A++ G L+ D I+SVN V+L+ THE A LKNAGQ++ ++ + +EY
Sbjct: 286 NDNYAPPDITNLDNHISPSGFIGHPLPPSPGRYSPAPKGMLEDDDLTREPRKVVLQRGTTGLGFNIVGG------EDGEGIFISFILAGGPADLSGELQKGDRIMSVNGVDLKSATHEQAAAALKNAGQTVTIVAQYRPEEY 421
BLAST of Disks large homolog 1 vs. Ensembl Xenopus
Match: hmmr (hyaluronan-mediated motility receptor (RHAMM) [Source:Xenbase;Acc:XB-GENE-5851601]) HSP 1 Score: 122.094 bits (305), Expect = 4.342e-29 Identity = 88/237 (37.13%), Postives = 123/237 (51.90%), Query Frame = 2
Query: 443 EPEANLEDENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
+P +++ + + Y +I L +G G GF++AGG + PH D GIF+TKII GAA +DGRL + D ++ VNDV++ V H AV+ LK AG + L++RR Q+ P T EV L+K GLG SI GG + D+ I I+K+ GG A DGRLQ+GD +L V++ +L V HEEAV LKNT V L +A+
Sbjct: 124 DPGSSVNGSDTLYKYEEIVLERGNSGLGFSIAGGIDNPHVPDDPGIFITKIIPGGAAAMDGRLSVSDCVLRVNDVDVTEVVHSKAVEALKEAGPVVRLLVRRR----------------QSPPET-----------------------IVEVNLLK-GPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQIGDRLLAVNNTNLQDVRHEEAVAALKNTSDMVYLKVAK 320 HSP 2 Score: 103.99 bits (258), Expect = 4.928e-23 Identity = 86/251 (34.26%), Postives = 125/251 (49.80%), Query Frame = 2
Query: 467 ENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRR----------LKDEYVANETTNLHEVVQATPNTGYYSPEHEQES----------------YHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTL 1141
++ P +++L KG KG GF++AGG H GDN I++TKII GAA+ DGRL+I D +++VN+ NL+ V HE AV LKN + L + + +Y + T + H + G Y E +S H E+ + ++ L K ST GLG +I GG E+ I +S + GG AD+ G L+ GD IL V+ +L THE+A LK G+TVT+
Sbjct: 227 QSPPETIVEVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQIGDRLLAVNNTNLQDVRHEEAVAALKNTSDMVYLKVAKPGPVHLNEIYAPPDYASTFTVDNH--ISHNSTLGAYLSSMESKSPYPPPQVTPSRFSPVPRHMLGEEDFTREPRKIILHKGST-GLGFNIVGG------EDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRSATHEQAAAALKRAGQTVTI 468 HSP 3 Score: 53.5286 bits (127), Expect = 5.380e-7 Identity = 39/96 (40.62%), Postives = 55/96 (57.29%), Query Frame = 2
Query: 491 QIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANET 778
+I L+KG G GF + GG E GIFV+ I+ G A++ G L+ D I+SVN VNL THE A LK AGQ++ ++ + +EY E+
Sbjct: 393 KIILHKGSTGLGFNIVGG------EDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRSATHEQAAAALKRAGQTVTIVAQYRPEEYSRFES 482
BLAST of Disks large homolog 1 vs. Ensembl Xenopus
Match: hmmr (hyaluronan-mediated motility receptor (RHAMM) [Source:Xenbase;Acc:XB-GENE-5851601]) HSP 1 Score: 122.094 bits (305), Expect = 4.876e-29 Identity = 88/237 (37.13%), Postives = 123/237 (51.90%), Query Frame = 2
Query: 443 EPEANLEDENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
+P +++ + + Y +I L +G G GF++AGG + PH D GIF+TKII GAA +DGRL + D ++ VNDV++ V H AV+ LK AG + L++RR Q+ P T EV L+K GLG SI GG + D+ I I+K+ GG A DGRLQ+GD +L V++ +L V HEEAV LKNT V L +A+
Sbjct: 124 DPGSSVNGSDTLYKYEEIVLERGNSGLGFSIAGGIDNPHVPDDPGIFITKIIPGGAAAMDGRLSVSDCVLRVNDVDVTEVVHSKAVEALKEAGPVVRLLVRRR----------------QSPPET-----------------------IVEVNLLK-GPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQIGDRLLAVNNTNLQDVRHEEAVAALKNTSDMVYLKVAK 320 HSP 2 Score: 103.605 bits (257), Expect = 5.589e-23 Identity = 86/251 (34.26%), Postives = 125/251 (49.80%), Query Frame = 2
Query: 467 ENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRR----------LKDEYVANETTNLHEVVQATPNTGYYSPEHEQES----------------YHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTL 1141
++ P +++L KG KG GF++AGG H GDN I++TKII GAA+ DGRL+I D +++VN+ NL+ V HE AV LKN + L + + +Y + T + H + G Y E +S H E+ + ++ L K ST GLG +I GG E+ I +S + GG AD+ G L+ GD IL V+ +L THE+A LK G+TVT+
Sbjct: 227 QSPPETIVEVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQIGDRLLAVNNTNLQDVRHEEAVAALKNTSDMVYLKVAKPGPVHLNEIYAPPDYASTFTVDNH--ISHNSTLGAYLSSMESKSPYPPPQVTPSRFSPVPRHMLGEEDFTREPRKIILHKGST-GLGFNIVGG------EDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRSATHEQAAAALKRAGQTVTI 468 HSP 3 Score: 53.9138 bits (128), Expect = 5.105e-7 Identity = 39/96 (40.62%), Postives = 55/96 (57.29%), Query Frame = 2
Query: 491 QIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANET 778
+I L+KG G GF + GG E GIFV+ I+ G A++ G L+ D I+SVN VNL THE A LK AGQ++ ++ + +EY E+
Sbjct: 393 KIILHKGSTGLGFNIVGG------EDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRSATHEQAAAALKRAGQTVTIVAQYRPEEYSRFES 482
BLAST of Disks large homolog 1 vs. Ensembl Xenopus
Match: hmmr (hyaluronan-mediated motility receptor (RHAMM) [Source:Xenbase;Acc:XB-GENE-5851601]) HSP 1 Score: 121.709 bits (304), Expect = 4.976e-29 Identity = 88/237 (37.13%), Postives = 123/237 (51.90%), Query Frame = 2
Query: 443 EPEANLEDENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
+P +++ + + Y +I L +G G GF++AGG + PH D GIF+TKII GAA +DGRL + D ++ VNDV++ V H AV+ LK AG + L++RR Q+ P T EV L+K GLG SI GG + D+ I I+K+ GG A DGRLQ+GD +L V++ +L V HEEAV LKNT V L +A+
Sbjct: 38 DPGSSVNGSDTLYKYEEIVLERGNSGLGFSIAGGIDNPHVPDDPGIFITKIIPGGAAAMDGRLSVSDCVLRVNDVDVTEVVHSKAVEALKEAGPVVRLLVRRR----------------QSPPET-----------------------IVEVNLLK-GPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQIGDRLLAVNNTNLQDVRHEEAVAALKNTSDMVYLKVAK 234 HSP 2 Score: 106.686 bits (265), Expect = 4.732e-24 Identity = 85/246 (34.55%), Postives = 125/246 (50.81%), Query Frame = 2
Query: 467 ENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRR-----LKDEYVANETTNLHEVVQATPNTGYYSPEHEQES----------------YHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTL 1141
++ P +++L KG KG GF++AGG H GDN I++TKII GAA+ DGRL+I D +++VN+ NL+ V HE AV LKN + L + + L + Y + ++ + G Y E +S H E+ + ++ L K ST GLG +I GG E+ I +S + GG AD+ G L+ GD IL V+ +L THE+A LK G+TVT+
Sbjct: 141 QSPPETIVEVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQIGDRLLAVNNTNLQDVRHEEAVAALKNTSDMVYLKVAKPGPVHLNEIYAPPDYASIDNHISHNSTLGAYLSSMESKSPYPPPQVTPSRFSPVPRHMLGEEDFTREPRKIILHKGST-GLGFNIVGG------EDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRSATHEQAAAALKRAGQTVTI 379 HSP 3 Score: 53.1434 bits (126), Expect = 6.795e-7 Identity = 39/96 (40.62%), Postives = 55/96 (57.29%), Query Frame = 2
Query: 491 QIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANET 778
+I L+KG G GF + GG E GIFV+ I+ G A++ G L+ D I+SVN VNL THE A LK AGQ++ ++ + +EY E+
Sbjct: 304 KIILHKGSTGLGFNIVGG------EDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRSATHEQAAAALKRAGQTVTIVAQYRPEEYSRFES 393
BLAST of Disks large homolog 1 vs. Ensembl Mouse
Match: Dlg1 (discs large MAGUK scaffold protein 1 [Source:MGI Symbol;Acc:MGI:107231]) HSP 1 Score: 119.398 bits (298), Expect = 1.383e-28 Identity = 96/269 (35.69%), Postives = 133/269 (49.44%), Query Frame = 2
Query: 347 ASPKPVSKVKSNDNYEPEDYPDYQDPNYNQEYEPEANLEDENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
A+P PV + + D+ E Y + D +Y EYE +I L +G G GF++AGG + PH D+ IF+TKIIT GAA DGRL+++D I+ VN+ ++ VTH AV+ LK AG + L ++R K P E + E+ LIK GLG SI GG + D+ I ++K+ GG A DG+LQ+GD +L V+ L VTHEEAV LKNT V L +A+
Sbjct: 162 ANPPPV--LVNTDSLETPTYVNGTDADY--EYE---------------EITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEADVRDVTHSKAVEALKEAGSIVRLYVKRRK-------------------------PASE--------------KIMEIKLIK-GPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSVCLEEVTHEEAVTALKNTSDFVYLKVAK 371 HSP 2 Score: 100.138 bits (248), Expect = 4.064e-22 Identity = 81/221 (36.65%), Postives = 117/221 (52.94%), Query Frame = 2
Query: 488 FQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRR--LKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLF 1144
+I L KG KG GF++AGG H GDN I+VTKII GAA DG+L+I D +++VN V LE VTHE AV LKN + L + + + V N + + Q + YSP + +++ ++ ++ R + GLG +I GG E+ I IS + GG AD+ G L+ GD I+ V+ L +HE+A LKN G+ VT+
Sbjct: 285 MEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSVCLEEVTHEEAVTALKNTSDFVYLKVAKPTTSSQSVDNHVSPSSCLGQTPTSPARYSPISKAVL-----GDDEITREPRKVVLHRGSTGLGFNIVGG------EDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVTIV 494 HSP 3 Score: 57.3806 bits (137), Expect = 2.519e-8 Identity = 36/79 (45.57%), Postives = 59/79 (74.68%), Query Frame = 2
Query: 2 MDIRKDDTERAVNLLKFYXXXXXXXXXXXXXXAMEKLIDTLETPLFSALLDIQEFYEVSL---SSAISGNKS--PVQPV 223
M +RK DT+RA++LL+ Y+SKL+++E++ L+ ++E++I+ ++ LF AL+DIQEFYEV+L + +K PVQPV
Sbjct: 1 MPVRKQDTQRALHLLEEYRSKLSQTEDRQLRSSIERVINIFQSNLFQALIDIQEFYEVTLLDNPKCVDHSKQCEPVQPV 79 HSP 4 Score: 50.447 bits (119), Expect = 4.085e-6 Identity = 46/138 (33.33%), Postives = 71/138 (51.45%), Query Frame = 2
Query: 356 KPVSKVKSNDNYEPEDYPDYQDPNYNQEYEP--EANLEDENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEY 763
KP + +S DN+ Q P Y P +A L D+ ++ L++G G GF + GG E GIF++ I+ G A++ G L+ D I+SVN V+L +HE A LKNAGQ++ ++ + +EY
Sbjct: 371 KPTTSSQSVDNHVSPSSCLGQTPTSPARYSPISKAVLGDDEITREPRKVVLHRGSTGLGFNIVGG------EDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVTIVAQYRPEEY 502
BLAST of Disks large homolog 1 vs. Ensembl Mouse
Match: Dlg1 (discs large MAGUK scaffold protein 1 [Source:MGI Symbol;Acc:MGI:107231]) HSP 1 Score: 120.168 bits (300), Expect = 1.707e-28 Identity = 85/223 (38.12%), Postives = 116/223 (52.02%), Query Frame = 2
Query: 485 YFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
Y +I L +G G GF++AGG + PH D+ IF+TKIIT GAA DGRL+++D I+ VN+ ++ VTH AV+ LK AG + L ++R K P E + E+ LIK GLG SI GG + D+ I ++K+ GG A DG+LQ+GD +L V+ L VTHEEAV LKNT V L +A+
Sbjct: 222 YEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEADVRDVTHSKAVEALKEAGSIVRLYVKRRK-------------------------PASE--------------KIMEIKLIK-GPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSVCLEEVTHEEAVTALKNTSDFVYLKVAK 404 HSP 2 Score: 97.4413 bits (241), Expect = 4.360e-21 Identity = 84/235 (35.74%), Postives = 120/235 (51.06%), Query Frame = 2
Query: 488 FQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRR-----LKDEYVANETTNL-----------HEVVQATPNT-GYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTL 1141
+I L KG KG GF++AGG H GDN I+VTKII GAA DG+L+I D +++VN V LE VTHE AV LKN + L + + + D Y + TN + TP + YSP + +++ ++ ++ R + GLG +I GG E+ I IS + GG AD+ G L+ GD I+ V+ L +HE+A LKN G+ VT+
Sbjct: 318 MEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSVCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMYINDGYAPPDITNSSSQSVDNHVSPSSCLGQTPTSPARYSPISKAVL-----GDDEITREPRKVVLHRGSTGLGFNIVGG------EDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVTI 541 HSP 3 Score: 74.7146 bits (182), Expect = 1.125e-13 Identity = 41/97 (42.27%), Postives = 58/97 (59.79%), Query Frame = 2
Query: 863 NAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
N + +++ E+TL +R GLG SI GG D + +DS I I+K+ GG A DGRL+V D IL V++ + VTH +AV LK G V L++ R
Sbjct: 214 NGTDADYEYEEITL-ERGNSGLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEADVRDVTHSKAVEALKEAGSIVRLYVKR 309 HSP 4 Score: 57.7658 bits (138), Expect = 2.248e-8 Identity = 36/79 (45.57%), Postives = 59/79 (74.68%), Query Frame = 2
Query: 2 MDIRKDDTERAVNLLKFYXXXXXXXXXXXXXXAMEKLIDTLETPLFSALLDIQEFYEVSL---SSAISGNKS--PVQPV 223
M +RK DT+RA++LL+ Y+SKL+++E++ L+ ++E++I+ ++ LF AL+DIQEFYEV+L + +K PVQPV
Sbjct: 1 MPVRKQDTQRALHLLEEYRSKLSQTEDRQLRSSIERVINIFQSNLFQALIDIQEFYEVTLLDNPKCVDHSKQCEPVQPV 79
BLAST of Disks large homolog 1 vs. Ensembl Mouse
Match: Dlg1 (discs large MAGUK scaffold protein 1 [Source:MGI Symbol;Acc:MGI:107231]) HSP 1 Score: 120.168 bits (300), Expect = 1.828e-28 Identity = 85/223 (38.12%), Postives = 116/223 (52.02%), Query Frame = 2
Query: 485 YFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
Y +I L +G G GF++AGG + PH D+ IF+TKIIT GAA DGRL+++D I+ VN+ ++ VTH AV+ LK AG + L ++R K P E + E+ LIK GLG SI GG + D+ I ++K+ GG A DG+LQ+GD +L V+ L VTHEEAV LKNT V L +A+
Sbjct: 222 YEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEADVRDVTHSKAVEALKEAGSIVRLYVKRRK-------------------------PASE--------------KIMEIKLIK-GPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSVCLEEVTHEEAVTALKNTSDFVYLKVAK 404 HSP 2 Score: 97.8265 bits (242), Expect = 3.863e-21 Identity = 84/235 (35.74%), Postives = 120/235 (51.06%), Query Frame = 2
Query: 488 FQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRR-----LKDEYVANETTNL-----------HEVVQATPNT-GYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTL 1141
+I L KG KG GF++AGG H GDN I+VTKII GAA DG+L+I D +++VN V LE VTHE AV LKN + L + + + D Y + TN + TP + YSP + +++ ++ ++ R + GLG +I GG E+ I IS + GG AD+ G L+ GD I+ V+ L +HE+A LKN G+ VT+
Sbjct: 318 MEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSVCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMYINDGYAPPDITNSSSQSVDNHVSPSSCLGQTPTSPARYSPISKAVL-----GDDEITREPRKVVLHRGSTGLGFNIVGG------EDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVTI 541 HSP 3 Score: 74.7146 bits (182), Expect = 1.133e-13 Identity = 41/97 (42.27%), Postives = 58/97 (59.79%), Query Frame = 2
Query: 863 NAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
N + +++ E+TL +R GLG SI GG D + +DS I I+K+ GG A DGRL+V D IL V++ + VTH +AV LK G V L++ R
Sbjct: 214 NGTDADYEYEEITL-ERGNSGLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEADVRDVTHSKAVEALKEAGSIVRLYVKR 309 HSP 4 Score: 57.7658 bits (138), Expect = 2.434e-8 Identity = 36/79 (45.57%), Postives = 59/79 (74.68%), Query Frame = 2
Query: 2 MDIRKDDTERAVNLLKFYXXXXXXXXXXXXXXAMEKLIDTLETPLFSALLDIQEFYEVSL---SSAISGNKS--PVQPV 223
M +RK DT+RA++LL+ Y+SKL+++E++ L+ ++E++I+ ++ LF AL+DIQEFYEV+L + +K PVQPV
Sbjct: 1 MPVRKQDTQRALHLLEEYRSKLSQTEDRQLRSSIERVINIFQSNLFQALIDIQEFYEVTLLDNPKCVDHSKQCEPVQPV 79
BLAST of Disks large homolog 1 vs. Ensembl Mouse
Match: Dlg1 (discs large MAGUK scaffold protein 1 [Source:MGI Symbol;Acc:MGI:107231]) HSP 1 Score: 120.168 bits (300), Expect = 1.828e-28 Identity = 85/223 (38.12%), Postives = 116/223 (52.02%), Query Frame = 2
Query: 485 YFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
Y +I L +G G GF++AGG + PH D+ IF+TKIIT GAA DGRL+++D I+ VN+ ++ VTH AV+ LK AG + L ++R K P E + E+ LIK GLG SI GG + D+ I ++K+ GG A DG+LQ+GD +L V+ L VTHEEAV LKNT V L +A+
Sbjct: 222 YEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEADVRDVTHSKAVEALKEAGSIVRLYVKRRK-------------------------PASE--------------KIMEIKLIK-GPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSVCLEEVTHEEAVTALKNTSDFVYLKVAK 404 HSP 2 Score: 97.8265 bits (242), Expect = 3.863e-21 Identity = 84/235 (35.74%), Postives = 120/235 (51.06%), Query Frame = 2
Query: 488 FQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRR-----LKDEYVANETTNL-----------HEVVQATPNT-GYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTL 1141
+I L KG KG GF++AGG H GDN I+VTKII GAA DG+L+I D +++VN V LE VTHE AV LKN + L + + + D Y + TN + TP + YSP + +++ ++ ++ R + GLG +I GG E+ I IS + GG AD+ G L+ GD I+ V+ L +HE+A LKN G+ VT+
Sbjct: 318 MEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSVCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMYINDGYAPPDITNSSSQSVDNHVSPSSCLGQTPTSPARYSPISKAVL-----GDDEITREPRKVVLHRGSTGLGFNIVGG------EDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVTI 541 HSP 3 Score: 74.7146 bits (182), Expect = 1.133e-13 Identity = 41/97 (42.27%), Postives = 58/97 (59.79%), Query Frame = 2
Query: 863 NAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
N + +++ E+TL +R GLG SI GG D + +DS I I+K+ GG A DGRL+V D IL V++ + VTH +AV LK G V L++ R
Sbjct: 214 NGTDADYEYEEITL-ERGNSGLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEADVRDVTHSKAVEALKEAGSIVRLYVKR 309 HSP 4 Score: 57.7658 bits (138), Expect = 2.434e-8 Identity = 36/79 (45.57%), Postives = 59/79 (74.68%), Query Frame = 2
Query: 2 MDIRKDDTERAVNLLKFYXXXXXXXXXXXXXXAMEKLIDTLETPLFSALLDIQEFYEVSL---SSAISGNKS--PVQPV 223
M +RK DT+RA++LL+ Y+SKL+++E++ L+ ++E++I+ ++ LF AL+DIQEFYEV+L + +K PVQPV
Sbjct: 1 MPVRKQDTQRALHLLEEYRSKLSQTEDRQLRSSIERVINIFQSNLFQALIDIQEFYEVTLLDNPKCVDHSKQCEPVQPV 79
BLAST of Disks large homolog 1 vs. Ensembl Mouse
Match: Dlg1 (discs large MAGUK scaffold protein 1 [Source:MGI Symbol;Acc:MGI:107231]) HSP 1 Score: 120.168 bits (300), Expect = 1.870e-28 Identity = 85/223 (38.12%), Postives = 116/223 (52.02%), Query Frame = 2
Query: 485 YFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
Y +I L +G G GF++AGG + PH D+ IF+TKIIT GAA DGRL+++D I+ VN+ ++ VTH AV+ LK AG + L ++R K P E + E+ LIK GLG SI GG + D+ I ++K+ GG A DG+LQ+GD +L V+ L VTHEEAV LKNT V L +A+
Sbjct: 222 YEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEADVRDVTHSKAVEALKEAGSIVRLYVKRRK-------------------------PASE--------------KIMEIKLIK-GPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSVCLEEVTHEEAVTALKNTSDFVYLKVAK 404 HSP 2 Score: 97.8265 bits (242), Expect = 3.879e-21 Identity = 84/235 (35.74%), Postives = 120/235 (51.06%), Query Frame = 2
Query: 488 FQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRR-----LKDEYVANETTNL-----------HEVVQATPNT-GYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTL 1141
+I L KG KG GF++AGG H GDN I+VTKII GAA DG+L+I D +++VN V LE VTHE AV LKN + L + + + D Y + TN + TP + YSP + +++ ++ ++ R + GLG +I GG E+ I IS + GG AD+ G L+ GD I+ V+ L +HE+A LKN G+ VT+
Sbjct: 318 MEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSVCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMYINDGYAPPDITNSSSQSVDNHVSPSSCLGQTPTSPARYSPISKAVL-----GDDEITREPRKVVLHRGSTGLGFNIVGG------EDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVTI 541 HSP 3 Score: 74.7146 bits (182), Expect = 1.050e-13 Identity = 41/97 (42.27%), Postives = 58/97 (59.79%), Query Frame = 2
Query: 863 NAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
N + +++ E+TL +R GLG SI GG D + +DS I I+K+ GG A DGRL+V D IL V++ + VTH +AV LK G V L++ R
Sbjct: 214 NGTDADYEYEEITL-ERGNSGLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEADVRDVTHSKAVEALKEAGSIVRLYVKR 309 HSP 4 Score: 57.7658 bits (138), Expect = 2.256e-8 Identity = 36/79 (45.57%), Postives = 59/79 (74.68%), Query Frame = 2
Query: 2 MDIRKDDTERAVNLLKFYXXXXXXXXXXXXXXAMEKLIDTLETPLFSALLDIQEFYEVSL---SSAISGNKS--PVQPV 223
M +RK DT+RA++LL+ Y+SKL+++E++ L+ ++E++I+ ++ LF AL+DIQEFYEV+L + +K PVQPV
Sbjct: 1 MPVRKQDTQRALHLLEEYRSKLSQTEDRQLRSSIERVINIFQSNLFQALIDIQEFYEVTLLDNPKCVDHSKQCEPVQPV 79
BLAST of Disks large homolog 1 vs. UniProt/SwissProt
Match: sp|Q6R005|DLG4_DANRE (Disks large homolog 4 OS=Danio rerio OX=7955 GN=dlg4 PE=2 SV=1) HSP 1 Score: 127.487 bits (319), Expect = 3.733e-30 Identity = 121/384 (31.51%), Postives = 180/384 (46.88%), Query Frame = 2
Query: 2 MDIRKDDTERAVNLLKFYXXXXXXXXXXXXXXAMEKLIDTLETPLFSALLDIQEFYEVSLSSAISGNKSPVQPVYNDIIPEAKLEVQETPVXXXXXXXXXXXXXXXXXXXXXXXIASPKPVSKVKSNDNYEPEDYPDYQDPNYNQEYEPEANLEDENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
M ++++DTERA+ ++ + ++ + E+L+ ++ LF ALLDIQEFYE+++ + ++ + E +Q +P L KS + S + I + P V +P P P Y + + Y +I L +G G GF++AGG + PH D IF+TKII GAA DGRL+++D I+ VNDV++ VTH AV+ LK AG + L + R H+ +AE E+ LIK GLG SI GG + D+ I ++K+ GG A DGRLQ+GD IL V++ L V HE+AV LKNTG V L +A+
Sbjct: 1 MPLKREDTERALQAME----ACQSAGDEGFRTRAERLLTIFQSDLFQALLDIQEFYELTVFENQTAGRALTPGLKYRYHDEETPPLQHSPAHLSTGKSAEMLHLGDSGHAPIDGIHAYTPQMHVSPA---KPVLLPSGHAPYYATS----TLMNGMDGDVEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNDVDVREVTHSFAVEALKEAGPIVRLYVLR-----------------------------------HKPSAEKIT----ELKLIK-GPKGLGFSIAGGVGNQHVPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNNMYLEEVMHEDAVAALKNTGDVVFLRVAK 333 HSP 2 Score: 116.316 bits (290), Expect = 2.321e-26 Identity = 86/234 (36.75%), Postives = 122/234 (52.14%), Query Frame = 2
Query: 491 QIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENA----------------ENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLF 1144
++ L KG KG GF++AGG H GDN I+VTKII GAA DGRL+I D I++VN++ LE V HE AV LKN G + L + + ++ + N ++ T YSP + Y + + ++D ++ +I R + GLG +I GG E+ I IS + GG AD+ G L+ GD IL V+ L THE+A LKN G+TVT+
Sbjct: 248 ELKLIKGPKGLGFSIAGGVGNQHVPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNNMYLEEVMHEDAVAALKNTGDVVFLRVAKTLHQHHHQDAYNPPDI------TSSYSPHMDMSDYPQALSPSSPRRYSPIPKGLFLDDDISREPRRVVIHRGSTGLGFNIVGG------EDGEGIFISFILAGGAADLSGELRKGDQILSVNGVDLRHATHEQAAAALKNAGQTVTII 469 HSP 3 Score: 61.6178 bits (148), Expect = 9.655e-9 Identity = 47/145 (32.41%), Postives = 77/145 (53.10%), Query Frame = 2
Query: 401 DYPDYQDPNYNQEYEP--EANLEDENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYS 829
DYP P+ + Y P + D++ ++ +++G G GF + GG E GIF++ I+ GAA++ G L+ D I+SVN V+L + THE A LKNAGQ++ +I + +EY E +H++ + N+ S
Sbjct: 361 DYPQALSPSSPRRYSPIPKGLFLDDDISREPRRVVIHRGSTGLGFNIVGG------EDGEGIFISFILAGGAADLSGELRKGDQILSVNGVDLRHATHEQAAAALKNAGQTVTIITQYRPEEYSRFE-AKIHDLREQLMNSSLVS 498
BLAST of Disks large homolog 1 vs. UniProt/SwissProt
Match: sp|G5ECY0|DLG1_CAEEL (Disks large homolog 1 OS=Caenorhabditis elegans OX=6239 GN=dlg-1 PE=1 SV=1) HSP 1 Score: 124.405 bits (311), Expect = 4.253e-29 Identity = 93/256 (36.33%), Postives = 128/256 (50.00%), Query Frame = 2
Query: 458 LEDENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEY-------VANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTG-------------------GLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFI 1147
++D W I L KG G GF++ GG ++P +GD I+VT II GAA DGR++ +D+I +VN+ N E V HE AV+ LK++G + L ++R KDE T+ L V TP+ + +H S +L + S G GLG SI GG + + D+ I ++K+ G A++DGRL+VGD IL VD SL THE AVN LKNTG V L I
Sbjct: 191 IDDHGRKWELENIVLEKGHTGLGFSITGGMDQPTEDGDTSIYVTNIIEGGAALADGRMRKNDIITAVNNTNCENVKHEVAVNALKSSGNVVSLSLKRRKDEAFLPIGGNFGGSTSYLRSGV--TPSVSAGNLQHAIHSPSAPIHPPPPPPVHHGSLSQLSVGQYRSTRPNTSVIDLVKGARGLGFSIAGGQGNEHVKGDTDIYVTKIIEEGAAELDGRLRVGDKILEVDHHSLINTTHENAVNVLKNTGNRVRLLI 444 HSP 2 Score: 113.62 bits (283), Expect = 1.910e-25 Identity = 85/238 (35.71%), Postives = 120/238 (50.42%), Query Frame = 2
Query: 494 IDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQE--------------------SYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFI 1147
IDL KG +G GF++AGG H +GD I+VTKII EGAAE+DGRL++ D I+ V+ +L THE AV+ LKN G + L+I++ + + Q P T P Q+ SY + + V L+K GLG +I GG E++ I IS + PGGVAD+ G ++ GD++L V+ L TH+EA L+N G V L +
Sbjct: 362 IDLVKGARGLGFSIAGGQGNEHVKGDTDIYVTKIIEEGAAELDGRLRVGDKILEVDHHSLINTTHENAVNVLKNTGNRVRLLIQQGTGAIFNDSASQ-----QFMPTTPILRPSSVQDYNRSQMGSQSHLSYGGPLNTSYSSQAPIAIPLEPRPVQLVK-GQNGLGFNIVGG------EDNEPIYISFVLPGGVADLSGNVKTGDVLLEVNGVVLRNATHKEAAEALRNAGNPVYLTL 587 HSP 3 Score: 63.1586 bits (152), Expect = 3.155e-9 Identity = 32/89 (35.96%), Postives = 52/89 (58.43%), Query Frame = 2
Query: 887 QFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
+ E ++++ GLG SI GG D + D+ I ++ + GG A DGR++ D+I V++ + V HE AVN LK++G V+L + R
Sbjct: 199 ELENIVLEKGHTGLGFSITGGMDQPTEDGDTSIYVTNIIEGGAALADGRMRKNDIITAVNNTNCENVKHEVAVNALKSSGNVVSLSLKR 287
BLAST of Disks large homolog 1 vs. UniProt/SwissProt
Match: sp|Q811D0|DLG1_MOUSE (Disks large homolog 1 OS=Mus musculus OX=10090 GN=Dlg1 PE=1 SV=1) HSP 1 Score: 120.168 bits (300), Expect = 1.278e-27 Identity = 85/223 (38.12%), Postives = 116/223 (52.02%), Query Frame = 2
Query: 485 YFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
Y +I L +G G GF++AGG + PH D+ IF+TKIIT GAA DGRL+++D I+ VN+ ++ VTH AV+ LK AG + L ++R K P E + E+ LIK GLG SI GG + D+ I ++K+ GG A DG+LQ+GD +L V+ L VTHEEAV LKNT V L +A+
Sbjct: 222 YEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEADVRDVTHSKAVEALKEAGSIVRLYVKRRK-------------------------PASE--------------KIMEIKLIK-GPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSVCLEEVTHEEAVTALKNTSDFVYLKVAK 404 HSP 2 Score: 97.8265 bits (242), Expect = 2.702e-20 Identity = 84/235 (35.74%), Postives = 120/235 (51.06%), Query Frame = 2
Query: 488 FQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRR-----LKDEYVANETTNL-----------HEVVQATPNT-GYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTL 1141
+I L KG KG GF++AGG H GDN I+VTKII GAA DG+L+I D +++VN V LE VTHE AV LKN + L + + + D Y + TN + TP + YSP + +++ ++ ++ R + GLG +I GG E+ I IS + GG AD+ G L+ GD I+ V+ L +HE+A LKN G+ VT+
Sbjct: 318 MEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSVCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMYINDGYAPPDITNSSSQSVDNHVSPSSCLGQTPTSPARYSPISKAVL-----GDDEITREPRKVVLHRGSTGLGFNIVGG------EDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVTI 541 HSP 3 Score: 74.7146 bits (182), Expect = 7.927e-13 Identity = 41/97 (42.27%), Postives = 58/97 (59.79%), Query Frame = 2
Query: 863 NAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
N + +++ E+TL +R GLG SI GG D + +DS I I+K+ GG A DGRL+V D IL V++ + VTH +AV LK G V L++ R
Sbjct: 214 NGTDADYEYEEITL-ERGNSGLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEADVRDVTHSKAVEALKEAGSIVRLYVKR 309 HSP 4 Score: 57.7658 bits (138), Expect = 1.702e-7 Identity = 36/79 (45.57%), Postives = 59/79 (74.68%), Query Frame = 2
Query: 2 MDIRKDDTERAVNLLKFYXXXXXXXXXXXXXXAMEKLIDTLETPLFSALLDIQEFYEVSL---SSAISGNKS--PVQPV 223
M +RK DT+RA++LL+ Y+SKL+++E++ L+ ++E++I+ ++ LF AL+DIQEFYEV+L + +K PVQPV
Sbjct: 1 MPVRKQDTQRALHLLEEYRSKLSQTEDRQLRSSIERVINIFQSNLFQALIDIQEFYEVTLLDNPKCVDHSKQCEPVQPV 79
BLAST of Disks large homolog 1 vs. UniProt/SwissProt
Match: sp|Q12959|DLG1_HUMAN (Disks large homolog 1 OS=Homo sapiens OX=9606 GN=DLG1 PE=1 SV=2) HSP 1 Score: 119.398 bits (298), Expect = 2.022e-27 Identity = 86/223 (38.57%), Postives = 118/223 (52.91%), Query Frame = 2
Query: 485 YFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
Y +I L +G G GF++AGG + PH D+ IF+TKIIT GAA DGRL+++D I+ VN+V++ VTH AV+ LK AG + L ++R K P E + E+ LIK GLG SI GG + D+ I ++K+ GG A DG+LQ+GD +L V++ L VTHEEAV LKNT V L +A+
Sbjct: 222 YEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEVDVRDVTHSKAVEALKEAGSIVRLYVKRRK-------------------------PVSE--------------KIMEIKLIK-GPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNNVCLEEVTHEEAVTALKNTSDFVYLKVAK 404 HSP 2 Score: 97.0561 bits (240), Expect = 4.984e-20 Identity = 83/235 (35.32%), Postives = 120/235 (51.06%), Query Frame = 2
Query: 488 FQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRR-----LKDEYVANETTNLHE------------VVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTL 1141
+I L KG KG GF++AGG H GDN I+VTKII GAA DG+L+I D +++VN+V LE VTHE AV LKN + L + + + D Y + TN + Q + YSP + +++ ++ ++ R + GLG +I GG E+ I IS + GG AD+ G L+ GD I+ V+ L +HE+A LKN G+ VT+
Sbjct: 318 MEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNNVCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMYMNDGYAPPDITNSSSQPVDNHVSPSSFLGQTPASPARYSPVSKAVL-----GDDEITREPRKVVLHRGSTGLGFNIVGG------EDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVTI 541 HSP 3 Score: 73.559 bits (179), Expect = 1.441e-12 Identity = 41/97 (42.27%), Postives = 58/97 (59.79%), Query Frame = 2
Query: 863 NAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
N + +++ E+TL +R GLG SI GG D + +DS I I+K+ GG A DGRL+V D IL V++ + VTH +AV LK G V L++ R
Sbjct: 214 NGTDADYEYEEITL-ERGNSGLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEVDVRDVTHSKAVEALKEAGSIVRLYVKR 309 HSP 4 Score: 57.7658 bits (138), Expect = 1.601e-7 Identity = 36/79 (45.57%), Postives = 59/79 (74.68%), Query Frame = 2
Query: 2 MDIRKDDTERAVNLLKFYXXXXXXXXXXXXXXAMEKLIDTLETPLFSALLDIQEFYEVSL---SSAISGNK--SPVQPV 223
M +RK DT+RA++LL+ Y+SKL+++E++ L+ ++E++I+ ++ LF AL+DIQEFYEV+L I +K P+QPV
Sbjct: 1 MPVRKQDTQRALHLLEEYRSKLSQTEDRQLRSSIERVINIFQSNLFQALIDIQEFYEVTLLDNPKCIDRSKPSEPIQPV 79
BLAST of Disks large homolog 1 vs. UniProt/SwissProt
Match: sp|Q5PYH7|DLG2_DANRE (Disks large homolog 2 OS=Danio rerio OX=7955 GN=dlg2 PE=2 SV=1) HSP 1 Score: 117.857 bits (294), Expect = 6.686e-27 Identity = 84/223 (37.67%), Postives = 116/223 (52.02%), Query Frame = 2
Query: 485 YFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
+ +I L +G G GF++AGG + PH D GIF+TKII GAA DGRL+++D I+ VN+ ++ V+H AV+ LK AG + L +RR + + E V E+ LIK GLG SI GG + D+ I ++K+ GG A DGRLQVGD +L V++ +L VTHEEAV LKNT V L + +
Sbjct: 153 FEEITLERGNSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNESDVSEVSHSKAVEALKAAGSIVRLYVRRRRP---------MLETVT------------------------------EIKLIK-GPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYTLEEVTHEEAVAILKNTSDVVYLKVGK 335 HSP 2 Score: 107.842 bits (268), Expect = 1.566e-23 Identity = 93/263 (35.36%), Postives = 127/263 (48.29%), Query Frame = 2
Query: 491 QIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRR-----LKDEYVANETTNLHEVVQATPN---------------------TGYYS--PEH--------EQESYHEENAENDNFQQFEV-----TLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIARF 1156
+I L KG KG GF++AGG H GDN I+VTKII GAA+ DGRL++ D ++ VN+ LE VTHE AV LKN + L + + L D Y + T H A N G YS P+H S E + Q F++ ++ + + GLG +I GG E+ I +S + GG AD+ G L+ GD IL V+ L G THE+A LK G+TVT+ IA++
Sbjct: 250 EIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYTLEEVTHEEAVAILKNTSDVVYLKVGKPTSVYLSDPYGPPDIT--HSFSPAMENHISSPGNNGTLEYKSSLPPISPGRYSPLPKHLLGEEDINRNPSLDEMEGHRFDSQHFQLREPRKIVLHKGSTGLGFNIVGG------EDGEGIFVSFILAGGPADLSGELRRGDQILSVNGIDLRGATHEQAAAALKGAGQTVTI-IAQY 503 HSP 3 Score: 74.3294 bits (181), Expect = 8.785e-13 Identity = 38/89 (42.70%), Postives = 54/89 (60.67%), Query Frame = 2
Query: 887 QFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
+FE ++R GLG SI GG D + +D I I+K+ PGG A DGRL+V D IL V++ ++ V+H +AV LK G V L++ R
Sbjct: 152 EFEEITLERGNSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNESDVSEVSHSKAVEALKAAGSIVRLYVRR 240 HSP 4 Score: 53.1434 bits (126), Expect = 4.179e-6 Identity = 37/91 (40.66%), Postives = 53/91 (58.24%), Query Frame = 2
Query: 491 QIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEY 763
+I L+KG G GF + GG E GIFV+ I+ G A++ G L+ D I+SVN ++L THE A LK AGQ++ +I + +EY
Sbjct: 424 KIVLHKGSTGLGFNIVGG------EDGEGIFVSFILAGGPADLSGELRRGDQILSVNGIDLRGATHEQAAAALKGAGQTVTIIAQYRPEEY 508
BLAST of Disks large homolog 1 vs. TrEMBL
Match: A0A2P1GIU4 (DLG OS=Oscarella lobularis OX=121494 PE=2 SV=1) HSP 1 Score: 150.984 bits (380), Expect = 1.407e-35 Identity = 142/403 (35.24%), Postives = 203/403 (50.37%), Query Frame = 2
Query: 2 MDIRKDDTERAVNLLKFYXXXXXXXXXXXXXXAMEKLIDTLETPLFSALLDIQEFYEVSLSSAISGNKSPVQPVYNDIIPEAKLEVQETPVXXXXXXXXXXXXXXXXXXXXXXX-----IASPKPVSK------VKSNDNYEPEDYPDY----QDPNYNQEYEPEANLEDENNP--WLYFQ--IDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
M RK D RA+ LL+ Y +KL ++++ L+ A+EK+I + LF ALLDIQEFYE +L + KS Q + + A E Q +P+ KK+K + AS PV+ ++ +E + + D + P E + D+ P W + Q I L KG G GF++AGGY+ PH DN ++VTKII G A DGRL++DD I+SVN L+YVTH AVD L++AG +IL+++R + V AT SP+ E + E+ L+K + GLG SI GG + D+ I ++K+ G A DGRL VGD IL V++ S+ VTHEEAV LK T +TV L + +
Sbjct: 25 MPARKQDAHRALELLEDYHAKLTGTDDRQLRSAIEKVIRIFRSRLFQALLDIQEFYEETL---LDSGKSKEQKTHETMEMAAAWEKQ-SPMPHKKKKEVAVSATAAATAAAVVVEKENDKASSSPVASDLLPPPPEATVTFERQAFLDESMPPEIPPSTSGVEVSPIVVDQPGPDKWQWEQETIILEKGSSGLGFSIAGGYDHPHSPDDNLVYVTKIIPTGGAAKDGRLRLDDCILSVNGNELKYVTHGEAVDALRHAGNRVILLVKR-----------KVLLVEMAT------SPKGEGRIH-------------EIKLVK-AGKGLGFSIAGGVGNQHIPGDNGIFVTKIIDTGAAAADGRLSVGDRILRVNEGSVENVTHEEAVQALKMTDQTVILLVEK 392 HSP 2 Score: 116.316 bits (290), Expect = 5.886e-24 Identity = 84/227 (37.00%), Postives = 114/227 (50.22%), Query Frame = 2
Query: 491 QIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLK--------DEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFI 1147
+I L K KG GF++AGG H GDNGIFVTKII GAA DGRL + D I+ VN+ ++E VTHE AV LK Q++IL++ + K + V + H+VV + Y A D +K+ + GLG +I GG E+ I IS + GG AD G L+ GD I+ V+ + THE+A LK G TVT+ +
Sbjct: 307 EIKLVKAGKGLGFSIAGGVGNQHIPGDNGIFVTKIIDTGAAAADGRLSVGDRILRVNEGSVENVTHEEAVQALKMTDQTVILLVEKAKKDENDGAFSQPVVTSSPMPHQVVDVS--VASYEESASPTKVDAARASRD----LRTVELKKGSTGLGFNIIGG------EDGEGIFISFILAGGAADRSGMLRRGDQIIEVNGADMRLATHEDAALALKGAGSTVTMVV 521
BLAST of Disks large homolog 1 vs. TrEMBL
Match: A0A4W4FCC0 (Uncharacterized protein OS=Electrophorus electricus OX=8005 PE=3 SV=1) HSP 1 Score: 148.673 bits (374), Expect = 9.851e-35 Identity = 135/398 (33.92%), Postives = 202/398 (50.75%), Query Frame = 2
Query: 2 MDIRKDDTERAVNLLKFYXXXXXXXXXXXXXXAMEKLIDTLETPLFSALLDIQEFYEVSLSSAISGNKSPVQPVYNDIIPEAKL----EVQETPVXXXXXXXXXXXXXXXXXXXXXXXIASPKPVSKVKSNDNYEPEDYPDYQDPNYNQ-----EYEPEANLE-----DENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
M +RK+D +RA+ LL+ Y++KLN +E++ LK +++++ID ++ LF AL+DIQEFYEV+L + K D P+A L VQ T V S + + + ++ ASP+ S + DN + + N +Q Y A++ + Y +I L +G G GF++AGG + PH D GIF+TK+I GAA DGRL+++DVI+ VN+V++ VTH AV+ LK AG + L +RR K ++ E + E+ L+K GLG SI GG + D+ I ++K+ GG A DGRLQ+GD +L V+ L VTHE+AV LKNT V L +A+
Sbjct: 1 MPVRKNDAQRALLLLEEYRTKLNNAEDRPLKNSIQRVIDIFQSNLFQALIDIQEFYEVTL---LDNQKCGASLKVTDAAPQANLWDFSSVQNTSVTSDTLPSLSTSTEKYRQHDED---ASPQEQSSPQLTDNTPDPELVQVAEKNISQIENVHGYVAHAHISPLKVNGTEADYEYEEITLERGNSGLGFSIAGGTDNPHIGEDPGIFITKVIPGGAAAQDGRLRVNDVILRVNEVDVRDVTHSKAVEALKEAGSLVRLYVRRRK---------SVSEKI------------------------------VEIKLVK-GPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKLLAVNSTCLEEVTHEQAVTALKNTTDVVYLKVAK 352 HSP 2 Score: 112.849 bits (281), Expect = 9.341e-23 Identity = 86/237 (36.29%), Postives = 120/237 (50.63%), Query Frame = 2
Query: 491 QIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRR-----LKDEYVANETTNLHE------------VVQATPNT--GYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLF 1144
+I L KG KG GF++AGG H GDN I+VTKII GAA DGRL+I D +++VN LE VTHE AV LKN + L + + + D + + TN + + Q P T G YSP + ++D ++ ++ R GLG +I GG E+ I IS + GG AD+ G L+ GD ++ V+ L THE+A LKN G+ VT+
Sbjct: 267 EIKLVKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKLLAVNSTCLEEVTHEQAVTALKNTTDVVYLKVAKPNNVFMNDNFAPPDITNSYSQHMENHISPPSFLSQPVPPTTSGPYSP-----TPRPTGGDDDITREPRKVVLHRGATGLGFNIVGG------EDGEGIFISFILAGGPADLSGELRKGDRLVSVNGVDLRSATHEQAAAALKNAGQIVTII 492
BLAST of Disks large homolog 1 vs. TrEMBL
Match: W5KTN9 (Discs, large homolog 1 (Drosophila) OS=Astyanax mexicanus OX=7994 PE=3 SV=2) HSP 1 Score: 147.517 bits (371), Expect = 2.097e-34 Identity = 125/399 (31.33%), Postives = 193/399 (48.37%), Query Frame = 2
Query: 2 MDIRKDDTERAVNLLKFYXXXXXXXXXXXXXXAMEKLIDTLETPLFSALLDIQEFYEVSLSSAISGNKSPVQPVYNDII--PEAKLEVQETPVXXXXXXXXXXXXXXXXXXXXXXXIASPKPVSKVKSNDNYEPEDY---PDYQDPNYNQEYEPE----------ANLEDENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
M +RK+DT+RA+ LL+ Y+SKL+++++ +++++E++I+ ++ LF AL+DIQEFYEVSL P +P + P + ++ P + P ++ Y+ ED P++ P + +P + +E+ + + I KG G GF++AGG + PH D IF+TKII GAA DGRL+++D I+ VNDVN+ VTH AV+ LK AG + L +RR K P E + ++ L+K GLG SI GG + D+ I ++K+ GG A DGRLQ+GD ++ V+ L VTHE+AV LKNT V L +A+
Sbjct: 1 MPVRKNDTQRALKLLEEYRSKLSQTKDPQIRQSIERVINIFQSSLFQALIDIQEFYEVSLQEKPDACTEPSEPAQPSLPSPPANQWDITSIPSTSAAVE------------------TQPSSLTSTSEKYRYQDEDTTSPPEHSSPRLPADLQPPELVQVSEKNISQIENVHGFVSHSHISPMKGNSGLGFSIAGGTDNPHIGEDPSIFITKIIPGGAAAQDGRLRVNDCILRVNDVNVRDVTHSKAVEALKEAGCIVRLYVRRRK-------------------------PGSE--------------KIVDLKLVK-GPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKLVAVNAACLEEVTHEDAVAALKNTTDVVYLKVAK 341 HSP 2 Score: 112.079 bits (279), Expect = 1.371e-22 Identity = 88/237 (37.13%), Postives = 120/237 (50.63%), Query Frame = 2
Query: 494 IDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRR-----LKDEYVANETTNLHE----------------VVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTL 1141
+ L KG KG GF++AGG H GDN I+VTKII GAA DGRL+I D +V+VN LE VTHE AV LKN + L + + + D Y + TN + + ATP+ YSP + EE ++ ++ R + GLG +I GG E+ I IS + GG AD+ G L+ GD ++ V+ L THE+A LKN G+TVT+
Sbjct: 257 LKLVKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKLVAVNAACLEEVTHEDAVAALKNTTDVVYLKVAKPTSVFMNDSYAPPDVTNSYSQHMENHITTPNYLSQPLTPATPSR--YSPVSKSTLGDEEIT-----REPRKVVLHRGSTGLGFNIVGG------EDGEGIFISFILAGGPADLCGELRKGDRLISVNGVDLRSATHEQAAAALKNAGQTVTI 480
BLAST of Disks large homolog 1 vs. TrEMBL
Match: F7CY76 (PIN2 (TERF1) interacting telomerase inhibitor 1 OS=Xenopus tropicalis OX=8364 GN=map3k15 PE=3 SV=2) HSP 1 Score: 147.517 bits (371), Expect = 2.220e-34 Identity = 133/388 (34.28%), Postives = 192/388 (49.48%), Query Frame = 2
Query: 2 MDIRKDDTERAVNLLKFYXXXXXXXXXXXXXXAMEKLIDTLETPLFSALLDIQEFYEVSL--SSAISGNKSPVQPVYNDIIPEAKLEVQETPVXXXXXXXXXXXXXXXXXXXXXXXIASPKPVSKVKSNDNYEPEDYPDYQDPNY--NQEYEPEANLEDENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
M +RK DT+RA+ LL+ Y+ KL+++E+K L+K++E++I ++ LF AL+DIQEFYEV+L + S N P +PV E T S + I PV V + N P P P N + E A + + + Y +I L +G G GF++AGG + PH D IF+TKII+ GAA DGRL+++D I+ VN+V++ VTH AV+ LK AG + L +RR K P E + ++ L+K GLG SI GG + D+ I ++K+ GG A DGRLQ+GD +L V+ L V+HE+AV LKNT V L +A+
Sbjct: 1 MPVRKQDTQRALTLLEEYRCKLHQTEDKQLRKSIERVIGIFQSNLFQALIDIQEFYEVTLLDNPKSSDNAKPTEPVQTINTWEYSSLPNSTATCETLPSSLILNVETPEADTPCPPIVPVIPVIPVPAESNVIPSSTPQANPPPVIVNTDLETPAYVNGTDAEYEYEEITLERGTSGLGFSIAGGTDNPHIGDDISIFITKIISGGAAAQDGRLRVNDCILRVNEVDVHDVTHSKAVEALKEAGSIVRLYVRRRK-------------------------PVTE--------------KIMDIKLVK-GPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKLLAVNTVCLEEVSHEDAVTALKNTSDFVNLKVAK 348 HSP 2 Score: 116.316 bits (290), Expect = 5.979e-24 Identity = 90/235 (38.30%), Postives = 122/235 (51.91%), Query Frame = 2
Query: 494 IDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRR-----LKDEYVANETTNLHEVV-------------QATPNTGYYSPEHEQESYHEENAENDNF-QQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTL 1141
I L KG KG GF++AGG H GDN I+VTKII GAA DGRL+I D +++VN V LE V+HE AV LKN + L + + + D Y + TN + P+ G YSP + E+D+ ++ +++R T GLG +I GG E+ I IS + GG AD+ G LQ GD I+ V+ L THE+A LKN G+TVT+
Sbjct: 264 IKLVKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKLLAVNTVCLEEVSHEDAVTALKNTSDFVNLKVAKPTTMYMNDNYAPPDITNSYSQQVDNHISPSGFIGHPLPPSPGRYSPAPKG------MLEDDDLTREPRKVVLQRGTTGLGFNIVGG------EDGEGIFISFILAGGPADLSGELQKGDRIMSVNGVDLKSATHEQAAAALKNAGQTVTI 486
BLAST of Disks large homolog 1 vs. TrEMBL
Match: A0A2K5KXB5 (Discs large MAGUK scaffold protein 1 OS=Cercocebus atys OX=9531 GN=DLG1 PE=3 SV=1) HSP 1 Score: 147.517 bits (371), Expect = 2.269e-34 Identity = 136/418 (32.54%), Postives = 201/418 (48.09%), Query Frame = 2
Query: 2 MDIRKDDTERAVNLLKFYXXXXXXXXXXXXXXAMEKLIDTLETPLFSALLDIQEFYEVSL---SSAISGNK--SPVQPVYNDIIPEAKLEVQETPVXXXXXXXXXXXXXXXXXXXXXXXIASPKPVSKVKSNDNYEPEDYP--DYQDPNYNQE-------YEPEANLEDENN--------------------PWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
M +RK DT+RA++LL+ Y+SKL+++E++ L+ ++E++I+ ++ LF AL+DIQEFYEV+L I +K P+QPV E+ P ++ P +S Y+ ED P ++ P E + E NL + N + Y +I L +G G GF++AGG + PH D+ IF+TKIIT GAA DGRL+++D I+ VN+V++ VTH AV+ LK AG + L ++R K P E + E+ LIK GLG SI GG + D+ I ++K+ GG A DG+LQ+GD +L V++ L VTHEEAV LKNT V L +A+
Sbjct: 1 MPVRKQDTQRALHLLEEYRSKLSQTEDRQLRSSIERVINIFQSNLFQALIDIQEFYEVTLLDNPKCIDRSKLSEPIQPVNT-------WEISSLPSSTVTSETL------------------PSSLSPSVEKYRYQDEDTPPQEHISPQITNEVVGPELVHVSEKNLSEIENVHGFVSHSHISPIKVNGTDADYEYEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEVDVRDVTHSKAVEALKEAGSIVRLYVKRRK-------------------------PVSE--------------KIMEIKLIK-GPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNNVCLEEVTHEEAVTALKNTSDFVYLKVAK 353 HSP 2 Score: 98.9821 bits (245), Expect = 2.790e-18 Identity = 84/234 (35.90%), Postives = 121/234 (51.71%), Query Frame = 2
Query: 488 FQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRR-----LKDEYVANETTNLHEVV-----------QATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTL 1141
+I L KG KG GF++AGG H GDN I+VTKII GAA DG+L+I D +++VN+V LE VTHE AV LKN + L + + + D Y + TN + V Q + YSP + +++ ++ ++ R + GLG +I GG E+ I IS + GG AD+ G L+ GD I+ V+ L +HE+A LKN G+ VT+
Sbjct: 267 MEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNNVCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMYMNDGYAPPDITNSSQPVDNHVSPSSFLGQTPASPARYSPVSKAVL-----GDDEITREPRKVVLHRGSTGLGFNIVGG------EDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVTI 489
BLAST of Disks large homolog 1 vs. Ensembl Cavefish
Match: dlg1 (disks large homolog 1 [Source:NCBI gene;Acc:103021716]) HSP 1 Score: 147.517 bits (371), Expect = 7.943e-38 Identity = 125/399 (31.33%), Postives = 193/399 (48.37%), Query Frame = 2
Query: 2 MDIRKDDTERAVNLLKFYXXXXXXXXXXXXXXAMEKLIDTLETPLFSALLDIQEFYEVSLSSAISGNKSPVQPVYNDII--PEAKLEVQETPVXXXXXXXXXXXXXXXXXXXXXXXIASPKPVSKVKSNDNYEPEDY---PDYQDPNYNQEYEPE----------ANLEDENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
M +RK+DT+RA+ LL+ Y+SKL+++++ +++++E++I+ ++ LF AL+DIQEFYEVSL P +P + P + ++ P + P ++ Y+ ED P++ P + +P + +E+ + + I KG G GF++AGG + PH D IF+TKII GAA DGRL+++D I+ VNDVN+ VTH AV+ LK AG + L +RR K P E + ++ L+K GLG SI GG + D+ I ++K+ GG A DGRLQ+GD ++ V+ L VTHE+AV LKNT V L +A+
Sbjct: 1 MPVRKNDTQRALKLLEEYRSKLSQTKDPQIRQSIERVINIFQSSLFQALIDIQEFYEVSLQEKPDACTEPSEPAQPSLPSPPANQWDITSIPSTSAAVE------------------TQPSSLTSTSEKYRYQDEDTTSPPEHSSPRLPADLQPPELVQVSEKNISQIENVHGFVSHSHISPMKGNSGLGFSIAGGTDNPHIGEDPSIFITKIIPGGAAAQDGRLRVNDCILRVNDVNVRDVTHSKAVEALKEAGCIVRLYVRRRK-------------------------PGSE--------------KIVDLKLVK-GPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKLVAVNAACLEEVTHEDAVAALKNTTDVVYLKVAK 341 HSP 2 Score: 112.079 bits (279), Expect = 5.191e-26 Identity = 88/237 (37.13%), Postives = 120/237 (50.63%), Query Frame = 2
Query: 494 IDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRR-----LKDEYVANETTNLHE----------------VVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTL 1141
+ L KG KG GF++AGG H GDN I+VTKII GAA DGRL+I D +V+VN LE VTHE AV LKN + L + + + D Y + TN + + ATP+ YSP + EE ++ ++ R + GLG +I GG E+ I IS + GG AD+ G L+ GD ++ V+ L THE+A LKN G+TVT+
Sbjct: 257 LKLVKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKLVAVNAACLEEVTHEDAVAALKNTTDVVYLKVAKPTSVFMNDSYAPPDVTNSYSQHMENHITTPNYLSQPLTPATPSR--YSPVSKSTLGDEEIT-----REPRKVVLHRGSTGLGFNIVGG------EDGEGIFISFILAGGPADLCGELRKGDRLISVNGVDLRSATHEQAAAALKNAGQTVTI 480 HSP 3 Score: 55.4546 bits (132), Expect = 8.029e-8 Identity = 52/156 (33.33%), Postives = 78/156 (50.00%), Query Frame = 2
Query: 356 KPVSKVKSNDNYEPED----YPDYQD-----PNYNQE---------YEP--EANLEDENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEY 763
KP S V ND+Y P D Y + + PNY + Y P ++ L DE ++ L++G G GF + GG E GIF++ I+ G A++ G L+ D ++SVN V+L THE A LKNAGQ++ ++ + +EY
Sbjct: 341 KPTS-VFMNDSYAPPDVTNSYSQHMENHITTPNYLSQPLTPATPSRYSPVSKSTLGDEEITREPRKVVLHRGSTGLGFNIVGG------EDGEGIFISFILAGGPADLCGELRKGDRLISVNGVDLRSATHEQAAAALKNAGQTVTIVAQYRPEEY 489
BLAST of Disks large homolog 1 vs. Ensembl Cavefish
Match: dlg3 (discs, large homolog 3 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-050208-93]) HSP 1 Score: 138.272 bits (347), Expect = 1.177e-34 Identity = 129/389 (33.16%), Postives = 191/389 (49.10%), Query Frame = 2
Query: 8 IRKDDTERAVNLLKFYXXXXXXXXXXXXXXAMEKLIDTLETPLFSALLDIQEFYEVSLSSAIS-------GNKSPVQPVYNDIIPEAKLEVQETPVXXXXXXXXXXXXXXXXXXXXXXXIASPKPVSKVKSNDNYEPEDYPDYQDPNYNQEYEPEANLEDENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
+ K DTERAV LLK Y++ L EE++L+ ++ K+ + LF ALLDIQE YEV+L + G K ++ + + ++ + +P K+++ S+ H ++ + A+P P+ + + D+ + Y + D Y Y +I L +G G GF++AGG + PH D GIF+TKII GAA +DGRL ++D ++ VN+V++ V H AV+ LK AG + L++RR QA P T EV L+K GLG SI GG + D+ I I+K+ GG A DGRLQ GD +L V++ L V HEEAV LKNT V L +A+
Sbjct: 2 VHKYDTERAVGLLKQYQASLTSPEEQALRTSVGKVSAIFGSQLFKALLDIQECYEVTLQLNTTENGIKENGPKETLENSEEECVSRVRVTSRRSPQKVERVAGLVSRSHVETPK------ANPPPI--IVNADSLDAGPYVNGSDGMYK-----------------YEEIILERGNSGLGFSIAGGIDNPHIPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNEVDVSEVVHSRAVEALKEAGPVVRLLVRRR----------------QAPPET-----------------------ILEVNLLK-GPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQTGDRLLAVNNIILQDVRHEEAVAALKNTSDMVYLKVAK 325 HSP 2 Score: 107.842 bits (268), Expect = 1.599e-24 Identity = 81/247 (32.79%), Postives = 122/247 (49.39%), Query Frame = 2
Query: 476 PWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRR-----LKDEYV---------------ANETTNLHEVVQATPNTGYYSPEHEQESY----HEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLF 1144
P +++L KG KG GF++AGG H GDN I++TKII GAA+ DGRL+ D +++VN++ L+ V HE AV LKN + L + + L D Y + +++ + P Y P+ Y E+D ++ L+ + + GLG +I GG E+ I +S + GG AD+ G L+ GD IL V+ +L THE+A LK G+TVT+
Sbjct: 235 PETILEVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQTGDRLLAVNNIILQDVRHEEAVAALKNTSDMVYLKVAKPGPVHLNDMYAPPDYSSTFPTMVDNHVSHNSSMAYMGGMEPKPVYQPPQVTPSRYSPVPRHMLGEDDFTREPRKVLLHKGSTGLGFNIVGG------EDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQTVTII 475 HSP 3 Score: 52.373 bits (124), Expect = 7.378e-7 Identity = 57/181 (31.49%), Postives = 80/181 (44.20%), Query Frame = 2
Query: 344 IASPKPVSKVKSNDNYEPEDY---------------------------PDYQDPNYN-QEYEP--EANLEDENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEV 796
+A P PV ND Y P DY P YQ P Y P L +++ ++ L+KG G GF + GG E GIFV+ I+ G A++ G L+ D I+SVN VNL THE A LK AGQ++ +I + +EY E + +H++
Sbjct: 323 VAKPGPV---HLNDMYAPPDYSSTFPTMVDNHVSHNSSMAYMGGMEPKPVYQPPQVTPSRYSPVPRHMLGEDDFTREPRKVLLHKGSTGLGFNIVGG------EDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQTVTIIAQYRPEEYSRFE-SKIHDL 493
BLAST of Disks large homolog 1 vs. Ensembl Cavefish
Match: dlg3 (discs, large homolog 3 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-050208-93]) HSP 1 Score: 119.783 bits (299), Expect = 1.645e-28 Identity = 87/225 (38.67%), Postives = 116/225 (51.56%), Query Frame = 2
Query: 479 WLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
+ Y +I L +G G GF++AGG + PH D GIF+TKII GAA +DGRL ++D ++ VN+V++ V H AV+ LK AG + L++RR QA P T EV L+K GLG SI GG + D+ I I+K+ GG A DGRLQ GD +L V++ L V HEEAV LKNT V L +A+
Sbjct: 122 YKYEEIILERGNSGLGFSIAGGIDNPHIPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNEVDVSEVVHSRAVEALKEAGPVVRLLVRRR----------------QAPPET-----------------------ILEVNLLK-GPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQTGDRLLAVNNIILQDVRHEEAVAALKNTSDMVYLKVAK 306 HSP 2 Score: 107.842 bits (268), Expect = 1.302e-24 Identity = 81/247 (32.79%), Postives = 122/247 (49.39%), Query Frame = 2
Query: 476 PWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRR-----LKDEYV---------------ANETTNLHEVVQATPNTGYYSPEHEQESY----HEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLF 1144
P +++L KG KG GF++AGG H GDN I++TKII GAA+ DGRL+ D +++VN++ L+ V HE AV LKN + L + + L D Y + +++ + P Y P+ Y E+D ++ L+ + + GLG +I GG E+ I +S + GG AD+ G L+ GD IL V+ +L THE+A LK G+TVT+
Sbjct: 216 PETILEVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQTGDRLLAVNNIILQDVRHEEAVAALKNTSDMVYLKVAKPGPVHLNDMYAPPDYSSTFPTMVDNHVSHNSSMAYMGGMEPKPVYQPPQVTPSRYSPVPRHMLGEDDFTREPRKVLLHKGSTGLGFNIVGG------EDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQTVTII 456 HSP 3 Score: 73.9442 bits (180), Expect = 1.293e-13 Identity = 37/94 (39.36%), Postives = 54/94 (57.45%), Query Frame = 2
Query: 872 NDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
+D ++E +++R GLG SI GG D + +D I I+K+ PGG A +DGRL V D +L V++ ++ V H AV LK G V L + R
Sbjct: 118 SDGMYKYEEIILERGNSGLGFSIAGGIDNPHIPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNEVDVSEVVHSRAVEALKEAGPVVRLLVRR 211 HSP 4 Score: 52.7582 bits (125), Expect = 7.081e-7 Identity = 39/96 (40.62%), Postives = 55/96 (57.29%), Query Frame = 2
Query: 491 QIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANET 778
++ L+KG G GF + GG E GIFV+ I+ G A++ G L+ D I+SVN VNL THE A LK AGQ++ +I + +EY E+
Sbjct: 380 KVLLHKGSTGLGFNIVGG------EDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQTVTIIAQYRPEEYSRFES 469
BLAST of Disks large homolog 1 vs. Ensembl Cavefish
Match: dlg3 (discs, large homolog 3 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-050208-93]) HSP 1 Score: 119.398 bits (298), Expect = 2.025e-28 Identity = 87/225 (38.67%), Postives = 116/225 (51.56%), Query Frame = 2
Query: 479 WLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
+ Y +I L +G G GF++AGG + PH D GIF+TKII GAA +DGRL ++D ++ VN+V++ V H AV+ LK AG + L++RR QA P T EV L+K GLG SI GG + D+ I I+K+ GG A DGRLQ GD +L V++ L V HEEAV LKNT V L +A+
Sbjct: 97 YKYEEIILERGNSGLGFSIAGGIDNPHIPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNEVDVSEVVHSRAVEALKEAGPVVRLLVRRR----------------QAPPET-----------------------ILEVNLLK-GPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQTGDRLLAVNNIILQDVRHEEAVAALKNTSDMVYLKVAK 281 HSP 2 Score: 107.842 bits (268), Expect = 1.423e-24 Identity = 81/247 (32.79%), Postives = 122/247 (49.39%), Query Frame = 2
Query: 476 PWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRR-----LKDEYV---------------ANETTNLHEVVQATPNTGYYSPEHEQESY----HEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLF 1144
P +++L KG KG GF++AGG H GDN I++TKII GAA+ DGRL+ D +++VN++ L+ V HE AV LKN + L + + L D Y + +++ + P Y P+ Y E+D ++ L+ + + GLG +I GG E+ I +S + GG AD+ G L+ GD IL V+ +L THE+A LK G+TVT+
Sbjct: 191 PETILEVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQTGDRLLAVNNIILQDVRHEEAVAALKNTSDMVYLKVAKPGPVHLNDMYAPPDYSSTFPTMVDNHVSHNSSMAYMGGMEPKPVYQPPQVTPSRYSPVPRHMLGEDDFTREPRKVLLHKGSTGLGFNIVGG------EDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQTVTII 431 HSP 3 Score: 73.9442 bits (180), Expect = 1.320e-13 Identity = 37/94 (39.36%), Postives = 54/94 (57.45%), Query Frame = 2
Query: 872 NDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
+D ++E +++R GLG SI GG D + +D I I+K+ PGG A +DGRL V D +L V++ ++ V H AV LK G V L + R
Sbjct: 93 SDGMYKYEEIILERGNSGLGFSIAGGIDNPHIPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNEVDVSEVVHSRAVEALKEAGPVVRLLVRR 186 HSP 4 Score: 52.7582 bits (125), Expect = 7.079e-7 Identity = 39/96 (40.62%), Postives = 55/96 (57.29%), Query Frame = 2
Query: 491 QIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANET 778
++ L+KG G GF + GG E GIFV+ I+ G A++ G L+ D I+SVN VNL THE A LK AGQ++ +I + +EY E+
Sbjct: 355 KVLLHKGSTGLGFNIVGG------EDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQTVTIIAQYRPEEYSRFES 444
BLAST of Disks large homolog 1 vs. Ensembl Cavefish
Match: dlg3 (discs, large homolog 3 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-050208-93]) HSP 1 Score: 119.013 bits (297), Expect = 3.338e-28 Identity = 87/223 (39.01%), Postives = 115/223 (51.57%), Query Frame = 2
Query: 485 YFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
Y +I L +G G GF++AGG + PH D GIF+TKII GAA +DGRL ++D ++ VN+V++ V H AV+ LK AG + L++RR QA P T EV L+K GLG SI GG + D+ I I+K+ GG A DGRLQ GD +L V++ L V HEEAV LKNT V L +A+
Sbjct: 130 YEEIILERGNSGLGFSIAGGIDNPHIPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNEVDVSEVVHSRAVEALKEAGPVVRLLVRRR----------------QAPPET-----------------------ILEVNLLK-GPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQTGDRLLAVNNIILQDVRHEEAVAALKNTSDMVYLKVAK 312 HSP 2 Score: 107.457 bits (267), Expect = 1.964e-24 Identity = 83/251 (33.07%), Postives = 126/251 (50.20%), Query Frame = 2
Query: 476 PWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRR-----LKDEYV---------------ANETTNLHEVVQATPNTGYYSPEHEQESY----HEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIARF 1156
P +++L KG KG GF++AGG H GDN I++TKII GAA+ DGRL+ D +++VN++ L+ V HE AV LKN + L + + L D Y + +++ + P Y P+ Y E+D ++ L+ + + GLG +I GG E+ I +S + GG AD+ G L+ GD IL V+ +L THE+A LK G+TVT+ IA++
Sbjct: 222 PETILEVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQTGDRLLAVNNIILQDVRHEEAVAALKNTSDMVYLKVAKPGPVHLNDMYAPPDYSSTFPTMVDNHVSHNSSMAYMGGMEPKPVYQPPQVTPSRYSPVPRHMLGEDDFTREPRKVLLHKGSTGLGFNIVGG------EDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQTVTI-IAQY 465 HSP 3 Score: 73.9442 bits (180), Expect = 1.281e-13 Identity = 37/101 (36.63%), Postives = 58/101 (57.43%), Query Frame = 2
Query: 851 YHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
++++ +D ++E +++R GLG SI GG D + +D I I+K+ PGG A +DGRL V D +L V++ ++ V H AV LK G V L + R
Sbjct: 117 WYDQVNGSDGMYKYEEIILERGNSGLGFSIAGGIDNPHIPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNEVDVSEVVHSRAVEALKEAGPVVRLLVRR 217 HSP 4 Score: 52.7582 bits (125), Expect = 6.822e-7 Identity = 39/96 (40.62%), Postives = 55/96 (57.29%), Query Frame = 2
Query: 491 QIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANET 778
++ L+KG G GF + GG E GIFV+ I+ G A++ G L+ D I+SVN VNL THE A LK AGQ++ +I + +EY E+
Sbjct: 386 KVLLHKGSTGLGFNIVGG------EDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQTVTIIAQYRPEEYSRFES 475
BLAST of Disks large homolog 1 vs. Ensembl Sea Lamprey
Match: scrib (scribble planar cell polarity protein [Source:NCBI gene;Acc:368473]) HSP 1 Score: 83.5741 bits (205), Expect = 2.503e-17 Identity = 67/216 (31.02%), Postives = 111/216 (51.39%), Query Frame = 2
Query: 518 GYGFAVAGGYNKPHYEG-DNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSM-ILIIR-RLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGY-DLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
G G ++AGG Y+G D GIF++++ EG A + G +++ D ++ VN V L H+ AV LKN+G M +L++R R+ + A TT ++ + ++PE E E Q V L+ R+ GLG SI GG S I IS++ GG AD++G + V D +L ++ + H++AV L ++ ++T+ + R
Sbjct: 551 GLGISIAGGKGSTPYKGEDEGIFISRVSDEGPAGIAG-VRVGDKLLQVNGVVLVDAEHQEAVSALKNSGSVMELLVLRERMVEPEHAVLTTPAQPPLRERRSAVTFAPEPEPTVMRE---------QLSVRLL-RNERGLGFSIAGGKGSTPFKGSHSGIFISRIAEGGTADLEGTMAVADRVLAINGVDMTEARHDQAVALLTSSATSITMLLQR 755 HSP 2 Score: 67.3958 bits (163), Expect = 3.691e-12 Identity = 62/239 (25.94%), Postives = 115/239 (48.12%), Query Frame = 2
Query: 443 EPEANLEDENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGD-NGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNE---EDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFI 1147
EPE + E + L + +G GF++AGG ++G +GIF+++I G A+++G + + D ++++N V++ H+ AV L ++ S+ ++++R + + + + E S H E + E+ L+K + G LG+SI GG D +++ + I ISK+ G A ++VGD IL V+ + TH+EAV L + +F+
Sbjct: 658 EPEPTVMREQ-----LSVRLLRNERGLGFSIAGGKGSTPFKGSHSGIFISRIAEGGTADLEGTMAVADRVLAINGVDMTEARHDQAVALLTSSATSITMLLQREQAQGHKPPGRPSSPPPGYPLSPDEEDGDEEDGSNHVSEQEEHPYPVEEIVLLK-TDGPLGLSIVGGSDHSSHPFGIDKPGIFISKIIADGQA-AKTNMRVGDRILSVNGLDVRHCTHQEAVCALLGGKPAIHMFV 889
BLAST of Disks large homolog 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004677.1 (pep scaffold:Pmarinus_7.0:GL479538:28591:32639:-1 gene:ENSPMAG00000004260.1 transcript:ENSPMAT00000004677.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 60.8474 bits (146), Expect = 2.750e-11 Identity = 54/193 (27.98%), Postives = 85/193 (44.04%), Query Frame = 2
Query: 578 IFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIARF 1156
I + ++ EGAA DGRL D I+ VN +L THE A++ L+ + Q + L + R + Y ++ + LH F V L+K++ GLG+SI G + + + +S++ GG A+ DGRL GD IL VD + + + E LK V + + R
Sbjct: 4 IMIHEVYEEGAAAKDGRLWAGDQILKVNGTDLRSATHEDAINALRASPQLVRLYVYRDEARYRGDDESALH--------------------------------VFTVELLKKAGRGLGLSIVG------KKSGNGVFVSEVVHGGAAEADGRLTQGDQILSVDGEDVRSASQETVAAILKCAQGVVKMEVGRM 158
BLAST of Disks large homolog 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006056.1 (pep scaffold:Pmarinus_7.0:GL477535:225:55869:1 gene:ENSPMAG00000005437.1 transcript:ENSPMAT00000006056.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 62.7734 bits (151), Expect = 9.278e-11 Identity = 65/215 (30.23%), Postives = 100/215 (46.51%), Query Frame = 2
Query: 494 IDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNA--GQSMILIIRR-----LKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLK 1117
I L KG G GF +A + P G I+V I+++GAA DGRLK D ++ VN +++ T E V L++ G S+ L++ R L + A + + A SP+ +E F + L LG+S++G D N D I I + GG A DGRL+V D ++ V+ +SL G ++ EA+ L+
Sbjct: 415 IHLKKGLDGLGFTIAT-RDTP-VGGRTPIYVKSIMSKGAALSDGRLKSGDRLLEVNGLDVTSRTQEEVVAILRSTKLGGSVDLLVSRHHDVPLSPDDPAGLNSRVWRCSAAEEEDRLLSPDGSRE-----------FLTLHIPLHDMGAASLGVSVKGTKDRRTNA-DLGIFIKTIIAGGAAAKDGRLRVDDQLIAVNRESLLGRSNLEAMESLR 615
BLAST of Disks large homolog 1 vs. Ensembl Sea Lamprey
Match: lin7a (lin-7 homolog A (C. elegans) [Source:ZFIN;Acc:ZDB-GENE-040426-1665]) HSP 1 Score: 59.3066 bits (142), Expect = 1.044e-10 Identity = 34/75 (45.33%), Postives = 45/75 (60.00%), Query Frame = 2
Query: 923 GLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFI 1147
GLG +I GG E++S I IS++ PGGVAD G L+ GD +L V+ S+ G HE+AV LK TV L +
Sbjct: 89 GLGFNIMGG-----KEQNSPIYISRIIPGGVADRQGGLKRGDQLLSVNGVSVEGEHHEKAVELLKQAQGTVKLVV 158
BLAST of Disks large homolog 1 vs. Ensembl Sea Lamprey
Match: LIN7B (lin-7 homolog B, crumbs cell polarity complex component [Source:HGNC Symbol;Acc:HGNC:17788]) HSP 1 Score: 56.9954 bits (136), Expect = 5.772e-10 Identity = 32/75 (42.67%), Postives = 44/75 (58.67%), Query Frame = 2
Query: 923 GLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFI 1147
GLG ++ GG E++S I IS++ PGGVAD G L+ GD +L V+ S+ G HE AV LK +V L +
Sbjct: 79 GLGFNVMGG-----KEQNSPIYISRIIPGGVADRQGGLKRGDQLLSVNGVSVEGEHHERAVELLKQAQGSVKLVV 148
BLAST of Disks large homolog 1 vs. Ensembl Nematostella
Match: EDO46059 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RR65]) HSP 1 Score: 111.694 bits (278), Expect = 1.014e-28 Identity = 82/223 (36.77%), Postives = 117/223 (52.47%), Query Frame = 2
Query: 488 FQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIARF 1156
+I L +G G GF++AGG + PH + D GI++TK+I GAA DGRL+++D I+SVN N + H+ AVD LK AG + L+ + + +P E E+ LIK S G LG SI GG + D+ I I+K+ GG A DGRLQVGD I+ V+ ++L V+HE+AV LK T + VT+ ++R
Sbjct: 5 LEITLERGGSGLGFSIAGGTDNPHVDDDFGIYITKVIPGGAAAQDGRLQVNDCILSVNGTNTVDIEHQQAVDALKAAGSQVTLVREKKRGN----------------------APTRE-----------------EIVLIKGSKG-LGFSIAGGSGNQHVPGDNGIYITKIIEGGAAQQDGRLQVGDKIISVNLQNLEDVSHEDAVQVLKATKERVTIVVSRL 187 HSP 2 Score: 76.2554 bits (186), Expect = 4.324e-16 Identity = 46/91 (50.55%), Postives = 61/91 (67.03%), Query Frame = 2
Query: 491 QIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEY 763
+I L KG KG GF++AGG H GDNGI++TKII GAA+ DGRL++ D I+SVN NLE V+HE AV LK + + +++ RL Y
Sbjct: 101 EIVLIKGSKGLGFSIAGGSGNQHVPGDNGIYITKIIEGGAAQQDGRLQVGDKIISVNLQNLEDVSHEDAVQVLKATKERVTIVVSRLTAYY 191 HSP 3 Score: 70.4774 bits (171), Expect = 4.057e-14 Identity = 40/89 (44.94%), Postives = 55/89 (61.80%), Query Frame = 2
Query: 878 NFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLF 1144
N++ E+TL +R GLG SI GG D + ++D I I+K+ PGG A DGRLQV D IL V+ + + H++AV+ LK G VTL
Sbjct: 1 NYETLEITL-ERGGSGLGFSIAGGTDNPHVDDDFGIYITKVIPGGAAAQDGRLQVNDCILSVNGTNTVDIEHQQAVDALKAAGSQVTLV 88
BLAST of Disks large homolog 1 vs. Ensembl Nematostella
Match: EDO33432 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SS78]) HSP 1 Score: 97.0561 bits (240), Expect = 2.321e-21 Identity = 78/224 (34.82%), Postives = 115/224 (51.34%), Query Frame = 2
Query: 500 LNKGRKGYGFAVAGGY-NKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEY---VANETTNLHEVVQATPNTGY-YSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGY-DLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
+++ KG G +AGG + P+ E D GIF+++I G A DG L + D I+ VN V++ TH AVD LK+ G+ + L + R K E +T V + TG ++PE E E E E + +TL + GLG SI GG + D I ISK+ G A+ DGRL+VGD +L ++ + + H++AVN L + VTL + R
Sbjct: 571 IHRDTKGLGINIAGGKGSTPYKENDEGIFISRISENGPAGRDGILHVGDKILKVNGVDISNATHHQAVDVLKSTGKDITLYVVREKQEIEKRTVPKTAKDESVKEEPKKTGVRFAPEPEMEDI-ETRPEKET-----ITLKRGGDKGLGFSIAGGKGSTPYKDGDPGIFISKIAKDGTAERDGRLKVGDKVLSINSRDMKNAKHDDAVNMLTSGPSFVTLIVYR 788 HSP 2 Score: 90.1225 bits (222), Expect = 3.527e-19 Identity = 78/249 (31.33%), Postives = 123/249 (49.40%), Query Frame = 2
Query: 437 EYEPEANLED-ENNPWLYFQIDLNKGRKGYGFAVAGGY-NKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEV-VQATPNTGYY------SPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNE---EDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFI 1147
+ PE +ED E P G KG GF++AGG + P+ +GD GIF++KI +G AE DGRLK+ D ++S+N +++ H+ AV+ L + + LI+ R D + + T L Q P+ SP + Y A + + ++K+ LG SI GG D A++ ++ I ISK+ P GVA L++GD +L V+ K + TH++AV L + L +
Sbjct: 683 RFAPEPEMEDIETRPEKETITLKRGGDKGLGFSIAGGKGSTPYKDGDPGIFISKIAKDGTAERDGRLKVGDKVLSINSRDMKNAKHDDAVNMLTSGPSFVTLIVYR--DRVINKKMTPLTRAGKQYNPSPSRAGKQYNPSPARAGKQYSPSPARAEINHEI---ILKKGNNPLGFSIVGGSDHASHPFGMDEPGIFISKIVPTGVAATTN-LKIGDRVLMVNGKDMRNATHQDAVAALIANVSLIKLLV 925 HSP 3 Score: 66.2402 bits (160), Expect = 1.466e-11 Identity = 71/227 (31.28%), Postives = 99/227 (43.61%), Query Frame = 2
Query: 491 QIDLNKGRKGYGFAVAGGYNK---PHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLAN----NEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIA 1150
+I L KG GF++ GG + P + GIF++KI+ G A LKI D ++ VN ++ TH+ AV L A S+I ++ R P G ++H+ E LGISI+GG ++ D I ISK++ G A DGRL VG IL V+ SL G TH EAV L++ G VTL +
Sbjct: 840 EIILKKGNNPLGFSIVGGSDHASHPFGMDEPGIFISKIVPTGVAATTN-LKIGDRVLMVNGKDMRNATHQDAVAALI-ANVSLIKLLVR-----------------HDPPPKGL-----NDVNFHKSPGEK-----------------LGISIRGGAKGHPGNPLDKTDEGIFISKVSEGAAAHKDGRLMVGQRILEVNGVSLLGATHLEAVRALRSMGDRVTLLVC 1025
BLAST of Disks large homolog 1 vs. Ensembl Nematostella
Match: EDO33706 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRG3]) HSP 1 Score: 85.8853 bits (211), Expect = 8.556e-18 Identity = 73/224 (32.59%), Postives = 109/224 (48.66%), Query Frame = 2
Query: 500 LNK-GRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEY-VTHETAVDTLKNAGQSMILIIRR--LKDEYVANETTNLHEVVQATP-NTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIARF 1156
LNK G+ G GF+V G K G+ GIF+ +I EG A DGRL+ D I+S++ L+ ++HE A+ L+ + LI+ R + + T+ V+ TP N S S + +++Q E + GLG I GG S +SI + PGGVAD DGRLQ D I+ + D ++ G+ E+ L++ G V L I+R
Sbjct: 167 LNKPGQGGLGFSVVG--LKSENRGELGIFIQEIQEEGVAGRDGRLRESDQILSIDGQQLDSGISHEEAIVLLQKTRGEVELIVARGGIPRTGTSRTTSGASSVISRTPSNVSLVS----DASTTIPADDGTHWRQIETIDLHNDGTGLGFGIIGG-------RSSGVSIKTILPGGVADKDGRLQEHDQIMQIGDVNVGGMGSEQVAQVLRDAGSHVRLVISRL 377 HSP 2 Score: 67.781 bits (164), Expect = 6.012e-12 Identity = 42/104 (40.38%), Postives = 61/104 (58.65%), Query Frame = 2
Query: 842 QESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
Q++ + A ++ + F V L+K T GLGI+I G AN++E + I I + G A +DGRL+V D I+ V SL+G + EAV LK TG V+L +AR
Sbjct: 598 QQTLKDIQAGEEDVELFNVDLVK-GTRGLGITIAGYIGEANSDELAGIFIKSIAHGSTAALDGRLRVNDQIIQVGSVSLHGKNNGEAVEILKQTGPVVSLKVAR 700 HSP 3 Score: 61.6178 bits (148), Expect = 5.229e-10 Identity = 38/94 (40.43%), Postives = 55/94 (58.51%), Query Frame = 2
Query: 461 EDENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILII 742
E+ +P I+L +G +G GF++ GG+ PH GD I+V + GAA DGRLK D I++VN +L V+HE+AV LK +IL +
Sbjct: 1740 EESESPLQTKIIELERGPEGLGFSIVGGHGSPH--GDLPIYVKTVFPTGAASRDGRLKRGDQIIAVNGQSLVGVSHESAVSQLKKTRGKIILTV 1831 HSP 4 Score: 60.4622 bits (145), Expect = 1.102e-9 Identity = 60/221 (27.15%), Postives = 101/221 (45.70%), Query Frame = 2
Query: 485 YFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKD--EYVA--NETTNLHEV--------VQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRST---GGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEA 1102
+ + L+KG G G ++AGG N IF+ + + G AE DGR+K D I+ VN + ++H A LKN G S+ L + R ++ EY++ + + H +Q T +T SP + + + +KRS+ G + +S +L+ + YI K DGRL+ GD ++ VDD+++ G++H E
Sbjct: 1425 HLLVSLSKGNTGLGLSIAGGKGV----AVNRIFIVDVKSGGPAEQDGRIKQADEILEVNRTPVRGMSHYQASTVLKNTGTSVELALGRSREAAEYLSRTRQQASPHSTEPDIKPSNIQTTESTPSISPRGVEVAAGPRRTPPPVAPKPSTDSLKRSSPQAGSVTVSPTLLAELSGGQLVEYIDFVK---------DGRLRKGDQLIAVDDQAIVGLSHAEG 1632 HSP 5 Score: 58.9214 bits (141), Expect = 3.637e-9 Identity = 36/105 (34.29%), Postives = 59/105 (56.19%), Query Frame = 2
Query: 833 EHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFI 1147
+ + S ++ E+++ Q ++ ++R GLG SI GG+ + D I + + P G A DGRL+ GD I+ V+ +SL GV+HE AV+ LK T + L +
Sbjct: 1729 QQDSPSQSDDEEESESPLQTKIIELERGPEGLGFSIVGGH--GSPHGDLPIYVKTVFPTGAASRDGRLKRGDQIIAVNGQSLVGVSHESAVSQLKKTRGKIILTV 1831 HSP 6 Score: 56.9954 bits (136), Expect = 1.148e-8 Identity = 40/115 (34.78%), Postives = 61/115 (53.04%), Query Frame = 2
Query: 827 SPEHEQESYHEENAENDNFQQFEVT----LIKRSTG--GLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
+P+H + +E+ + +VT L+ S G GLG+SI GG +A N I I + GG A+ DGR++ D IL V+ + G++H +A LKNTG +V L + R
Sbjct: 1398 APDHSEMPSYEDRIRELQAKYPDVTGEHLLVSLSKGNTGLGLSIAGGKGVAVNR----IFIVDVKSGGPAEQDGRIKQADEILEVNRTPVRGMSHYQASTVLKNTGTSVELALGR 1508 HSP 7 Score: 53.9138 bits (128), Expect = 1.222e-7 Identity = 66/261 (25.29%), Postives = 109/261 (41.76%), Query Frame = 2
Query: 485 YFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMIL-IIRRLKDEYVANET--TNLHEVVQATPNTGY---------YSPEH------------------------EQESYHEENAENDNFQQFEVTLIKRS-TGGLGISIQGG-YDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
F +DL KG +G G +AG + + + GIF+ I A +DGRL+++D I+ V V+L + AV+ LK G + L + R + ++ ET + H + TP + + PE E H + DN + + K S GGLGIS++G Y L + + I + P G +G +Q GD ++ V+ + + H E V +++ L +AR
Sbjct: 613 LFNVDLVKGTRGLGITIAGYIGEANSDELAGIFIKSIAHGSTAALDGRLRVNDQIIQVGSVSLHGKNNGEAVEILKQTGPVVSLKVARHIPGKHSRPETPHSTPHSPGRQTPQSSHSPRSVTPVVIQPEKSIAVESADAKAEAELQRELQTLDTEAVKQHYQTIIGDNMEILVAEMTKFSPAGGLGISLEGTQYPLDGSM--PWHRIHAVNPEGPVGKNGIIQSGDHLIEVNGVGVLDLGHNEVVTLIQSLPMEFRLVVAR 871
BLAST of Disks large homolog 1 vs. Ensembl Nematostella
Match: EDO34828 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNC4]) HSP 1 Score: 68.5514 bits (166), Expect = 7.924e-14 Identity = 40/90 (44.44%), Postives = 54/90 (60.00%), Query Frame = 2
Query: 884 QQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
Q FEV LIK G LG+S+ GG E I I +L PGG A + G+LQV D+IL V+ KSL+ +T+ EA++ L+N V L + R
Sbjct: 40 QPFEVHLIKGPQG-LGMSLTGG------ESGGPIYIKRLVPGGSAALCGQLQVNDVILQVNGKSLDRLTYREALSILRNCPPEVRLLVKR 122
BLAST of Disks large homolog 1 vs. Ensembl Nematostella
Match: EDO45624 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RSE9]) HSP 1 Score: 66.2402 bits (160), Expect = 3.374e-12 Identity = 65/211 (30.81%), Postives = 92/211 (43.60%), Query Frame = 2
Query: 515 KGYGFAVAGGYNKPHYEGDNGIFVTKIITEGA-AEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLF 1144
+G G V GG + P G+ K I G AE G L+ D ++ VND L VTH A++ LKN + L + R KD P+ + + F V L K S G LGI + GG + I + + P GVA DGR++ GD +L V+ +S G+TH+E +N L+N + V LF
Sbjct: 7 QGIGLMVIGGLDTPL-----GMLYIKDIQPGTPAEKCGHLRTGDQLLQVNDECLVGVTHAYALEVLKNTPPLVKLTVARKKD------------------------PDRDSDV-------------FTVELKKDSKGSLGIHVSGGVG------TNCIDVRHVVPLGVAAKDGRIRKGDRVLSVNGRSTKGLTHQEVLNLLQNLPRRVRLF 169 HSP 2 Score: 49.2914 bits (116), Expect = 1.254e-6 Identity = 30/77 (38.96%), Postives = 42/77 (54.55%), Query Frame = 2
Query: 923 GLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
G+G+ + GG D + I + PG A+ G L+ GD +L V+D+ L GVTH A+ LKNT V L +AR
Sbjct: 8 GIGLMVIGGLD----TPLGMLYIKDIQPGTPAEKCGHLRTGDQLLQVNDECLVGVTHAYALEVLKNTPPLVKLTVAR 80
BLAST of Disks large homolog 1 vs. Ensembl Medaka
Match: dlg3 (discs large MAGUK scaffold protein 3 [Source:NCBI gene;Acc:101169708]) HSP 1 Score: 137.502 bits (345), Expect = 1.839e-34 Identity = 133/387 (34.37%), Postives = 185/387 (47.80%), Query Frame = 2
Query: 8 IRKDDTERAVNLLKFYXXXXXXXXXXXXXXAMEKLIDTLETPLFSALLDIQEFYEVSLSSAISGNKSPVQPVYNDIIPEAKLEVQETPVXXXXXXXXXXXXXXXXXXXXXXXIASPKPVSKVKSNDNYEPEDYPDYQDPNY-----NQEYEPEANLEDENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
+ + DTERAV LLK Y++ L EE++LK ++ K+ L + LF ALLDIQE YEV+L +S Q + + +++ +V E P + + + SP V +V D P P + + P N D + Y +I L +G G GF++AGG + PH D GIF+TKII GAA +DGRL ++D ++ VNDV++ V H AV+ LK AG + L++RR QA P T EV L+K GLG SI GG + D+ I I+K+ GG A DGRLQ GD +L V++ L V HEEAV LKNT V L +A+
Sbjct: 2 VHRYDTERAVGLLKQYQANLTSPEEQALKTSVGKVSAILGSHLFQALLDIQECYEVTL------QQSAEQTIVKE---DSRKDVWEDPEDEGVSRVRVTSSR------------SPHKVERVSGLVVLCHVDMPKANPPPIIVNADSLDAGPYVNGSDAM--YKYEEIILERGNSGLGFSIAGGIDNPHIPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNDVDVSEVVHSRAVEALKEAGPVVRLLVRRR----------------QAPPET-----------------------ILEVNLLK-GPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQTGDRLLAVNNIVLQDVRHEEAVAALKNTSDMVYLKVAK 325 HSP 2 Score: 108.612 bits (270), Expect = 8.074e-25 Identity = 87/244 (35.66%), Postives = 124/244 (50.82%), Query Frame = 2
Query: 476 PWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRR-----LKDEYVANETTNL----------HEVVQAT-PNTGYYSPEHEQESY-----HEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLF 1144
P +++L KG KG GF++AGG H GDN I++TKII GAA+ DGRL+ D +++VN++ L+ V HE AV LKN + L + + L D Y + ++ H + A P Y P+ Y H E+ + +V L K ST GLG +I GG E+ I +S + GG AD+ G L+ GD IL V+ +L THE+A LK G+TVT+
Sbjct: 235 PETILEVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQTGDRLLAVNNIVLQDVRHEEAVAALKNTSDMVYLKVAKPGPVHLNDMYAPPDYSSTFPTMVDNHVSHNYMGAMEPKPVYPPPQVTPSRYSPVPRHMMGEEDFTREPRKVVLHKGST-GLGFNIVGG------EDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQTVTII 471 HSP 3 Score: 52.7582 bits (125), Expect = 6.158e-7 Identity = 40/102 (39.22%), Postives = 59/102 (57.84%), Query Frame = 2
Query: 491 QIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEV 796
++ L+KG G GF + GG E GIFV+ I+ G A++ G L+ D I+SVN VNL THE A LK AGQ++ +I + +EY E + +H++
Sbjct: 395 KVVLHKGSTGLGFNIVGG------EDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQTVTIIAQYRPEEYSRFE-SKIHDL 489
BLAST of Disks large homolog 1 vs. Ensembl Medaka
Match: dlg3 (discs large MAGUK scaffold protein 3 [Source:NCBI gene;Acc:101169708]) HSP 1 Score: 137.502 bits (345), Expect = 2.082e-34 Identity = 134/384 (34.90%), Postives = 181/384 (47.14%), Query Frame = 2
Query: 20 DTERAVNLLKFYXXXXXXXXXXXXXXAMEKLIDTLETPLFSALLDIQEFYEVSLSSAISGNKSPVQPVYNDIIPE-AKLEVQETPVXXXXXXXXXXXXXXXXXXXXXXXIASPKPVSKVKSNDNYEPEDYPDYQDPNY-----NQEYEPEANLEDENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
DTERAV LLK Y++ L EE++LK ++ K+ L + LF ALLDIQE YEV+L Q I+ E ++ +V E P + + + SP V +V D P P + + P N D + Y +I L +G G GF++AGG + PH D GIF+TKII GAA +DGRL ++D ++ VNDV++ V H AV+ LK AG + L++RR QA P T EV L+K GLG SI GG + D+ I I+K+ GG A DGRLQ GD +L V++ L V HEEAV LKNT V L +A+
Sbjct: 9 DTERAVGLLKQYQANLTSPEEQALKTSVGKVSAILGSHLFQALLDIQECYEVTLQ----------QSAEQTIVKEDSRKDVWEDPEDEGVSRVRVTSSR------------SPHKVERVSGLVVLCHVDMPKANPPPIIVNADSLDAGPYVNGSDAM--YKYEEIILERGNSGLGFSIAGGIDNPHIPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNDVDVSEVVHSRAVEALKEAGPVVRLLVRRR----------------QAPPET-----------------------ILEVNLLK-GPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQTGDRLLAVNNIVLQDVRHEEAVAALKNTSDMVYLKVAK 328 HSP 2 Score: 108.997 bits (271), Expect = 6.444e-25 Identity = 87/244 (35.66%), Postives = 124/244 (50.82%), Query Frame = 2
Query: 476 PWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRR-----LKDEYVANETTNL----------HEVVQAT-PNTGYYSPEHEQESY-----HEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLF 1144
P +++L KG KG GF++AGG H GDN I++TKII GAA+ DGRL+ D +++VN++ L+ V HE AV LKN + L + + L D Y + ++ H + A P Y P+ Y H E+ + +V L K ST GLG +I GG E+ I +S + GG AD+ G L+ GD IL V+ +L THE+A LK G+TVT+
Sbjct: 238 PETILEVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQTGDRLLAVNNIVLQDVRHEEAVAALKNTSDMVYLKVAKPGPVHLNDMYAPPDYSSTFPTMVDNHVSHNYMGAMEPKPVYPPPQVTPSRYSPVPRHMMGEEDFTREPRKVVLHKGST-GLGFNIVGG------EDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQTVTII 474 HSP 3 Score: 52.7582 bits (125), Expect = 5.802e-7 Identity = 40/102 (39.22%), Postives = 59/102 (57.84%), Query Frame = 2
Query: 491 QIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEV 796
++ L+KG G GF + GG E GIFV+ I+ G A++ G L+ D I+SVN VNL THE A LK AGQ++ +I + +EY E + +H++
Sbjct: 398 KVVLHKGSTGLGFNIVGG------EDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQTVTIIAQYRPEEYSRFE-SKIHDL 492
BLAST of Disks large homolog 1 vs. Ensembl Medaka
Match: dlg3 (discs large MAGUK scaffold protein 3 [Source:NCBI gene;Acc:101169708]) HSP 1 Score: 119.783 bits (299), Expect = 1.792e-28 Identity = 88/223 (39.46%), Postives = 115/223 (51.57%), Query Frame = 2
Query: 485 YFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
Y +I L +G G GF++AGG + PH D GIF+TKII GAA +DGRL ++D ++ VNDV++ V H AV+ LK AG + L++RR QA P T EV L+K GLG SI GG + D+ I I+K+ GG A DGRLQ GD +L V++ L V HEEAV LKNT V L +A+
Sbjct: 150 YEEIILERGNSGLGFSIAGGIDNPHIPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNDVDVSEVVHSRAVEALKEAGPVVRLLVRRR----------------QAPPET-----------------------ILEVNLLK-GPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQTGDRLLAVNNIVLQDVRHEEAVAALKNTSDMVYLKVAK 332 HSP 2 Score: 108.997 bits (271), Expect = 6.522e-25 Identity = 89/248 (35.89%), Postives = 128/248 (51.61%), Query Frame = 2
Query: 476 PWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRR-----LKDEYVANETTNL----------HEVVQAT-PNTGYYSPEHEQESY-----HEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIARF 1156
P +++L KG KG GF++AGG H GDN I++TKII GAA+ DGRL+ D +++VN++ L+ V HE AV LKN + L + + L D Y + ++ H + A P Y P+ Y H E+ + +V L K ST GLG +I GG E+ I +S + GG AD+ G L+ GD IL V+ +L THE+A LK G+TVT+ IA++
Sbjct: 242 PETILEVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQTGDRLLAVNNIVLQDVRHEEAVAALKNTSDMVYLKVAKPGPVHLNDMYAPPDYSSTFPTMVDNHVSHNYMGAMEPKPVYPPPQVTPSRYSPVPRHMMGEEDFTREPRKVVLHKGST-GLGFNIVGG------EDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQTVTI-IAQY 481 HSP 3 Score: 75.485 bits (184), Expect = 3.958e-14 Identity = 38/94 (40.43%), Postives = 54/94 (57.45%), Query Frame = 2
Query: 872 NDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
+D ++E +++R GLG SI GG D + +D I I+K+ PGG A +DGRL V D +L V+D ++ V H AV LK G V L + R
Sbjct: 144 SDAMYKYEEIILERGNSGLGFSIAGGIDNPHIPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNDVDVSEVVHSRAVEALKEAGPVVRLLVRR 237 HSP 4 Score: 53.1434 bits (126), Expect = 4.801e-7 Identity = 40/102 (39.22%), Postives = 59/102 (57.84%), Query Frame = 2
Query: 491 QIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEV 796
++ L+KG G GF + GG E GIFV+ I+ G A++ G L+ D I+SVN VNL THE A LK AGQ++ +I + +EY E + +H++
Sbjct: 402 KVVLHKGSTGLGFNIVGG------EDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQTVTIIAQYRPEEYSRFE-SKIHDL 496
BLAST of Disks large homolog 1 vs. Ensembl Medaka
Match: dlg4a (disks large homolog 4 [Source:NCBI gene;Acc:101159214]) HSP 1 Score: 115.931 bits (289), Expect = 2.608e-27 Identity = 91/234 (38.89%), Postives = 122/234 (52.14%), Query Frame = 2
Query: 491 QIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANE------TTNLHEVVQATPNTGYY-----------SPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTL 1141
+I L KG KG GF++AGG H GDN I+VTKII GAA DGRL+I D I++VN+V LE V HE AV LKN + + L + + + ++ N TT H + + + GY SP H ++D ++ LI R + GLG +I GG E+ I IS + GG AD+ G L GD IL V+ L THE+A LKN G+TVT+
Sbjct: 143 EIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNNVCLEDVMHEDAVGALKNTAEVVYLRVAKPNNLFLTNSYNPPDLTTYSHMDTELS-HPGYLGSDYPQALTPTSPSRFSPVLHGMMGDDDIPREPRRILIHRGSTGLGFNIVGG------EDGEGIFISFILAGGPADLSGELHKGDQILSVNGVDLRMATHEQAAAALKNAGQTVTI 369 HSP 2 Score: 68.5514 bits (166), Expect = 5.718e-12 Identity = 54/158 (34.18%), Postives = 72/158 (45.57%), Query Frame = 2
Query: 680 VTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
VTH AV+ LK AG + L + R K P E+ + E+ LIK GLG SI GG + D+ I ++K+ GG A DGRLQ+GD IL V++ L V HE+AV LKNT + V L +A+
Sbjct: 111 VTHSQAVEALKEAGAIVRLYVLRRK-------------------------PAAEKVT--------------EIKLIK-GPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNNVCLEDVMHEDAVGALKNTAEVVYLRVAK 228 HSP 3 Score: 62.003 bits (149), Expect = 7.522e-10 Identity = 49/153 (32.03%), Postives = 76/153 (49.67%), Query Frame = 2
Query: 377 SNDNYEPEDYPDYQDPNYNQEYEP--EANLEDENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYS 829
S+ Y DYP P + P + D++ P +I +++G G GF + GG E GIF++ I+ G A++ G L D I+SVN V+L THE A LKNAGQ++ ++ + DEY E +H++ + N+ S
Sbjct: 254 SHPGYLGSDYPQALTPTSPSRFSPVLHGMMGDDDIPREPRRILIHRGSTGLGFNIVGG------EDGEGIFISFILAGGPADLSGELHKGDQILSVNGVDLRMATHEQAAAALKNAGQTVTIVAQYRPDEYSRFE-AKIHDLREQLMNSSMGS 399
BLAST of Disks large homolog 1 vs. Ensembl Medaka
Match: dlg4a (disks large homolog 4 [Source:NCBI gene;Acc:101159214]) HSP 1 Score: 115.931 bits (289), Expect = 3.310e-27 Identity = 89/234 (38.03%), Postives = 120/234 (51.28%), Query Frame = 2
Query: 491 QIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANE------TTNLHEVVQATPNTGYY-----------SPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTL 1141
+I L KG KG GF++AGG H GDN I+VTKII GAA DGRL+I D I++VN+V LE V HE AV LKN + + L + + + ++ N T+ + + GY SP H ++D ++ LI R + GLG +I GG E+ I IS + GG AD+ G L GD IL V+ L THE+A LKN G+TVT+
Sbjct: 213 EIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNNVCLEDVMHEDAVGALKNTAEVVYLRVAKPNNLFLTNSYNPPDLTSTYSHMDTELSHPGYLGSDYPQALTPTSPSRFSPVLHGMMGDDDIPREPRRILIHRGSTGLGFNIVGG------EDGEGIFISFILAGGPADLSGELHKGDQILSVNGVDLRMATHEQAAAALKNAGQTVTI 440 HSP 2 Score: 113.62 bits (283), Expect = 1.803e-26 Identity = 86/223 (38.57%), Postives = 115/223 (51.57%), Query Frame = 2
Query: 485 YFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
Y +I L +G G GF++AGG + PH D IF+TKII GAA DGRL ++D I+ VNDV++ VTH AV+ LK AG + L + R K P E+ + E+ LIK GLG SI GG + D+ I ++K+ GG A DGRLQ+GD IL V++ L V HE+AV LKNT + V L +A+
Sbjct: 116 YEEITLERGNSGLGFSIAGGTDNPHVGDDPSIFITKIIPGGAAAQDGRLSVNDCILFVNDVDVREVTHSQAVEALKEAGAIVRLYVLRRK-------------------------PAAEKVT--------------EIKLIK-GPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNNVCLEDVMHEDAVGALKNTAEVVYLRVAK 298 HSP 3 Score: 74.3294 bits (181), Expect = 1.103e-13 Identity = 39/89 (43.82%), Postives = 52/89 (58.43%), Query Frame = 2
Query: 887 QFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
++E ++R GLG SI GG D + +D I I+K+ PGG A DGRL V D IL V+D + VTH +AV LK G V L++ R
Sbjct: 115 EYEEITLERGNSGLGFSIAGGTDNPHVGDDPSIFITKIIPGGAAAQDGRLSVNDCILFVNDVDVREVTHSQAVEALKEAGAIVRLYVLR 203 HSP 4 Score: 61.6178 bits (148), Expect = 8.802e-10 Identity = 49/153 (32.03%), Postives = 76/153 (49.67%), Query Frame = 2
Query: 377 SNDNYEPEDYPDYQDPNYNQEYEP--EANLEDENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYS 829
S+ Y DYP P + P + D++ P +I +++G G GF + GG E GIF++ I+ G A++ G L D I+SVN V+L THE A LKNAGQ++ ++ + DEY E +H++ + N+ S
Sbjct: 325 SHPGYLGSDYPQALTPTSPSRFSPVLHGMMGDDDIPREPRRILIHRGSTGLGFNIVGG------EDGEGIFISFILAGGPADLSGELHKGDQILSVNGVDLRMATHEQAAAALKNAGQTVTIVAQYRPDEYSRFE-AKIHDLREQLMNSSMGS 470
BLAST of Disks large homolog 1 vs. Planmine SMEST
Match: SMESG000020502.1 (SMESG000020502.1) HSP 1 Score: 674.855 bits (1740), Expect = 0.000e+0 Identity = 418/418 (100.00%), Postives = 418/418 (100.00%), Query Frame = 2
Query: 2 MDIRKDDTERAVNLLKFYXXXXXXXXXXXXXXAMEKLIDTLETPLFSALLDIQEFYEVSLSSAISGNKSPVQPVYNDIIPEAKLEVQETPVXXXXXXXXXXXXXXXXXXXXXXXIASPKPVSKVKSNDNYEPEDYPDYQDPNYNQEYEPEANLEDENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIARFXXXXXXXXXXXXXXXXXXXXXXXXXXHRRDREE 1255
MDIRKDDTERAVNLLKFYKSKLNKSEEKSLKKAMEKLIDTLETPLFSALLDIQEFYEVSLSSAISGNKSPVQPVYNDIIPEAKLEVQETPVKLKKEKSKKSKRHQKSEEEQSEEIASPKPVSKVKSNDNYEPEDYPDYQDPNYNQEYEPEANLEDENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKIDDVIVSVNDVNLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIARFIPETVEQEPEPEEPIVEKTEKKKKKKHRRDREE
Sbjct: 1 MDIRKDDTERAVNLLKFYKSKLNKSEEKSLKKAMEKLIDTLETPLFSALLDIQEFYEVSLSSAISGNKSPVQPVYNDIIPEAKLEVQETPVKLKKEKSKKSKRHQKSEEEQSEEIASPKPVSKVKSNDNYEPEDYPDYQDPNYNQEYEPEANLEDENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKIDDVIVSVNDVNLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIARFIPETVEQEPEPEEPIVEKTEKKKKKKHRRDREE 418
BLAST of Disks large homolog 1 vs. Planmine SMEST
Match: SMESG000020500.1 (SMESG000020500.1) HSP 1 Score: 178.718 bits (452), Expect = 1.088e-52 Identity = 110/232 (47.41%), Postives = 153/232 (65.95%), Query Frame = 2
Query: 467 ENNPWLYFQIDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKD-EYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLAN-NEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIARF 1156
E + W++ ++ L KGRKG+GFA ++ + D+ I +TKI+ EG A+ DGRLKI D+IVSVNDV+ + V +E A+ TL+N G ++ + +RRLK+ Y ++E +++ PN S E + E FQQ EV L+KR+ GGLGI+I+GGY+ N +EED+YI ISKL GVA DGRLQVGD+IL VD +S +G+TH EAV LKN GK VT+F+ RF
Sbjct: 48 EGHEWIFIKVHLKKGRKGFGFAFIN--DRSIHREDDAISITKIVHEGVAQQDGRLKIGDIIVSVNDVDFDEVPYEKAISTLRNIGPNLTMTVRRLKEYCYESDENDDMN-----PPNAYEISDSFESDDQPE-------FQQLEVNLVKRAVGGLGINIEGGYNTENEDEEDNYIRISKLAVNGVAANDGRLQVGDIILQVDLQSFDGLTHYEAVEILKNCGKEVTIFVGRF 265
BLAST of Disks large homolog 1 vs. Planmine SMEST
Match: SMESG000034854.1 (SMESG000034854.1) HSP 1 Score: 98.9821 bits (245), Expect = 1.107e-21 Identity = 86/257 (33.46%), Postives = 123/257 (47.86%), Query Frame = 2
Query: 506 KGRKGYGFAVAGGYNKPHYE-GDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILII----------------RRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEE-------------------NAENDNFQQFE-----VTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
KG G+GF+VAGG + P++ D GI+VTKI G+ ++ G L IDD I+SVN +N+ Y+THE AV LK AG + L+I RR A+ ++ + QA ++ SPE+ + + H + N +F + ++LIK GLG SI GG + D I I+K+ G A G + GD ++ V+D L VTHEEAV L N G V L I +
Sbjct: 193 KGSTGFGFSVAGGIDNPYFHLNDPGIYVTKITPGGSVDLSGSLNIDDQILSVNGINMTYLTHEAAVSALKEAGDELHLVIQRDPTLKHRMSGLGYMRRKNASLTASTISDSRQDSQAEKSSSQVSPEYIKTNSHSSVWVTSSKASSVPSNLSQGIKSSNSSFVSLKSRIVTISLIK-GERGLGFSIGGGRGNEHYVGDPGIYITKVMDKGAAATCGLISEGDKLVQVNDYLLTDVTHEEAVKILCNVGSKVELKILK 448 HSP 2 Score: 97.8265 bits (242), Expect = 2.403e-21 Identity = 79/240 (32.92%), Postives = 114/240 (47.50%), Query Frame = 2
Query: 494 IDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEE------NAENDN----FQQFEVTLIKRS-----------TGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIA 1150
I L KG +G GF++ GG HY GD GI++TK++ +GAA G + D +V VND L VTHE AV L N G + L I + N T E P + S + ES N ++N F + + I +S T G G +I GG E++ I +S + P G+AD +G + VGD I V+ ++ TH+EA + LK +GKT+ L +
Sbjct: 364 ISLIKGERGLGFSIGGGRGNEHYVGDPGIYITKVMDKGAAATCGLISEGDKLVQVNDYLLTDVTHEEAVKILCNVGSKVELKILKPNSGVSNNVTEQFEE-----PFSNCQSSKDLSESLSNNDSPVRLNGSDNNHDIFFDEVDSNFINKSPRIVVLSRPNETVGFGFNIVGG------EDEDGIFVSFIIPSGIADKNGNIFVGDRIWQVNGTDISIATHDEAASLLKGSGKTLELLLT 592
BLAST of Disks large homolog 1 vs. Planmine SMEST
Match: SMESG000034854.1 (SMESG000034854.1) HSP 1 Score: 98.9821 bits (245), Expect = 1.132e-21 Identity = 86/257 (33.46%), Postives = 123/257 (47.86%), Query Frame = 2
Query: 506 KGRKGYGFAVAGGYNKPHYE-GDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILII----------------RRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEE-------------------NAENDNFQQFE-----VTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
KG G+GF+VAGG + P++ D GI+VTKI G+ ++ G L IDD I+SVN +N+ Y+THE AV LK AG + L+I RR A+ ++ + QA ++ SPE+ + + H + N +F + ++LIK GLG SI GG + D I I+K+ G A G + GD ++ V+D L VTHEEAV L N G V L I +
Sbjct: 181 KGSTGFGFSVAGGIDNPYFHLNDPGIYVTKITPGGSVDLSGSLNIDDQILSVNGINMTYLTHEAAVSALKEAGDELHLVIQRDPTLKHRMSGLGYMRRKNASLTASTISDSRQDSQAEKSSSQVSPEYIKTNSHSSVWVTSSKASSVPSNLSQGIKSSNSSFVSLKSRIVTISLIK-GERGLGFSIGGGRGNEHYVGDPGIYITKVMDKGAAATCGLISEGDKLVQVNDYLLTDVTHEEAVKILCNVGSKVELKILK 436 HSP 2 Score: 97.8265 bits (242), Expect = 2.690e-21 Identity = 79/240 (32.92%), Postives = 114/240 (47.50%), Query Frame = 2
Query: 494 IDLNKGRKGYGFAVAGGYNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEE------NAENDN----FQQFEVTLIKRS-----------TGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIA 1150
I L KG +G GF++ GG HY GD GI++TK++ +GAA G + D +V VND L VTHE AV L N G + L I + N T E P + S + ES N ++N F + + I +S T G G +I GG E++ I +S + P G+AD +G + VGD I V+ ++ TH+EA + LK +GKT+ L +
Sbjct: 352 ISLIKGERGLGFSIGGGRGNEHYVGDPGIYITKVMDKGAAATCGLISEGDKLVQVNDYLLTDVTHEEAVKILCNVGSKVELKILKPNSGVSNNVTEQFEE-----PFSNCQSSKDLSESLSNNDSPVRLNGSDNNHDIFFDEVDSNFINKSPRIVVLSRPNETVGFGFNIVGG------EDEDGIFVSFIIPSGIADKNGNIFVGDRIWQVNGTDISIATHDEAASLLKGSGKTLELLLT 580
BLAST of Disks large homolog 1 vs. Planmine SMEST
Match: SMESG000030959.1 (SMESG000030959.1) HSP 1 Score: 84.7297 bits (208), Expect = 4.930e-17 Identity = 63/214 (29.44%), Postives = 111/214 (51.87%), Query Frame = 2
Query: 515 KGYGFAVAGGYNKPHYEGDN-GIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRRLKDEYVANETTNLHEVVQATPNTGYYSPEHEQESYHEENAENDNFQQFEVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLKNTGKTVTLFIAR 1153
+G+GF + + G + G ++ K+I A+ G L++ D I+SVN ++ + HE V T+KN G+++ L I + +E + T+++ + + S SY + + + F+VTL R + G G SI+GG D + + ++ G A DGRL+VGD IL ++ KS G+TH +A+N ++ GK++ L + R
Sbjct: 1162 EGFGFVIVTSMTR---SGSHVGEYIGKLIENSPAQKCGLLRVGDRILSVNGNSVSRMRHEKIVQTIKNCGRNVTLRISPVPEEGGHSGPTSINSYESSDQGSSIRS---SNASYQKSDTNSSGDVDFDVTL-NRGSKGFGFSIRGGQDF----NKMPLFVLRIADDGPAKQDGRLKVGDKILQINGKSTTGMTHNQAINIIQAGGKSIRLLVRR 1364 HSP 2 Score: 57.7658 bits (138), Expect = 1.546e-8 Identity = 33/89 (37.08%), Postives = 56/89 (62.92%), Query Frame = 2
Query: 488 FQIDLNKGRKGYGFAVAGG--YNKPHYEGDNGIFVTKIITEGAAEVDGRLKXXXXXXXXXXXXLEYVTHETAVDTLKNAGQSMILIIRR 748
F + LN+G KG+GF++ GG +NK +FV +I +G A+ DGRLK+ D I+ +N + +TH A++ ++ G+S+ L++RR
Sbjct: 1282 FDVTLNRGSKGFGFSIRGGQDFNK------MPLFVLRIADDGPAKQDGRLKVGDKILQINGKSTTGMTHNQAINIIQAGGKSIRLLVRR 1364 HSP 3 Score: 55.8398 bits (133), Expect = 6.385e-8 Identity = 33/89 (37.08%), Postives = 50/89 (56.18%), Query Frame = 2
Query: 893 EVTLIKRSTGGLGISIQGGYDLANNEEDSYISISKLTPGGVADVDGRLQVGDLILHVDDKSLNGVTHEEAVNFLK--NTGKTVTLFIAR 1153
TLIK S G G +I GG D + E ++ I + PGG A VDGRL+ GD++++VD + G H + V + + G+ VTL + +
Sbjct: 575 RTTLIK-SPRGFGFTIIGGSDRSRPE---FLQIKHVMPGGPAAVDGRLETGDVLVYVDHTLVLGFLHADIVELFQCISIGQHVTLTVCK 659 The following BLAST results are available for this feature:
BLAST of Disks large homolog 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Disks large homolog 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Disks large homolog 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Disks large homolog 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Disks large homolog 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Disks large homolog 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Disks large homolog 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Disks large homolog 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Disks large homolog 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Disks large homolog 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Disks large homolog 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Disks large homolog 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Disks large homolog 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Disks large homolog 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30021297 ID=SMED30021297|Name=Disks large homolog 1|organism=Schmidtea mediterranea sexual|type=transcript|length=1364bpback to top protein sequence of SMED30021297-orf-1 >SMED30021297-orf-1 ID=SMED30021297-orf-1|Name=SMED30021297-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=419bp MDIRKDDTERAVNLLKFYKSKLNKSEEKSLKKAMEKLIDTLETPLFSALLback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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