cAMP-dependent protein kinase catalytic subunit
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30021250 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 3
Homology
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Human
Match: PRKACB (protein kinase cAMP-activated catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:9381]) HSP 1 Score: 561.992 bits (1447), Expect = 0.000e+0 Identity = 279/351 (79.49%), Postives = 314/351 (89.46%), Query Frame = 1
Query: 94 IGNNPNSKK-NDITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+GN +KK +++ VK FL +AK F++KW+ P+QN A L DFER +TLGTGSFGRVMLV+HK T++Y A+KILDKQKVVKLKQ+EHTLNEKRILQA+ F FLVRL+Y FKDNSNLYMV+E+V GGEMFSHLRRIGRFSEPH+RFYAAQIVL FEYLH LDLIYRDLKPENLLID QGYI+VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS+DLKDLLRNLLQVDLTKR+GNLKN V DIKTHKWF DWI I+++++EAPFIP +G GD+SNFDDYEEE +R++ TEKC KEF +F
Sbjct: 1 MGNAATAKKGSEVESVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Human
Match: PRKACB (protein kinase cAMP-activated catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:9381]) HSP 1 Score: 556.599 bits (1433), Expect = 0.000e+0 Identity = 277/342 (80.99%), Postives = 309/342 (90.35%), Query Frame = 1
Query: 124 DITD--VKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+I+D VK FL +AK F++KW+ P+QN A L DFER +TLGTGSFGRVMLV+HK T++Y A+KILDKQKVVKLKQ+EHTLNEKRILQA+ F FLVRL+Y FKDNSNLYMV+E+V GGEMFSHLRRIGRFSEPH+RFYAAQIVL FEYLH LDLIYRDLKPENLLID QGYI+VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS+DLKDLLRNLLQVDLTKR+GNLKN V DIKTHKWF DWI I+++++EAPFIP +G GD+SNFDDYEEE +R++ TEKC KEF +F
Sbjct: 16 EISDSFVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF 357
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Human
Match: PRKACB (protein kinase cAMP-activated catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:9381]) HSP 1 Score: 556.214 bits (1432), Expect = 0.000e+0 Identity = 277/341 (81.23%), Postives = 309/341 (90.62%), Query Frame = 1
Query: 124 DITD-VKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+I+D VK FL +AK F++KW+ P+QN A L DFER +TLGTGSFGRVMLV+HK T++Y A+KILDKQKVVKLKQ+EHTLNEKRILQA+ F FLVRL+Y FKDNSNLYMV+E+V GGEMFSHLRRIGRFSEPH+RFYAAQIVL FEYLH LDLIYRDLKPENLLID QGYI+VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS+DLKDLLRNLLQVDLTKR+GNLKN V DIKTHKWF DWI I+++++EAPFIP +G GD+SNFDDYEEE +R++ TEKC KEF +F
Sbjct: 17 EISDFVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF 357
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Human
Match: PRKACB (protein kinase cAMP-activated catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:9381]) HSP 1 Score: 556.214 bits (1432), Expect = 0.000e+0 Identity = 275/336 (81.85%), Postives = 305/336 (90.77%), Query Frame = 1
Query: 136 VKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
VK FL +AK F++KW+ P+QN A L DFER +TLGTGSFGRVMLV+HK T++Y A+KILDKQKVVKLKQ+EHTLNEKRILQA+ F FLVRL+Y FKDNSNLYMV+E+V GGEMFSHLRRIGRFSEPH+RFYAAQIVL FEYLH LDLIYRDLKPENLLID QGYI+VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS+DLKDLLRNLLQVDLTKR+GNLKN V DIKTHKWF DWI I+++++EAPFIP +G GD+SNFDDYEEE +R++ TEKC KEF +F
Sbjct: 20 VKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF 355
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Human
Match: PRKACB (protein kinase cAMP-activated catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:9381]) HSP 1 Score: 555.829 bits (1431), Expect = 0.000e+0 Identity = 277/342 (80.99%), Postives = 309/342 (90.35%), Query Frame = 1
Query: 124 DITD--VKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+I+D VK FL +AK F++KW+ P+QN A L DFER +TLGTGSFGRVMLV+HK T++Y A+KILDKQKVVKLKQ+EHTLNEKRILQA+ F FLVRL+Y FKDNSNLYMV+E+V GGEMFSHLRRIGRFSEPH+RFYAAQIVL FEYLH LDLIYRDLKPENLLID QGYI+VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS+DLKDLLRNLLQVDLTKR+GNLKN V DIKTHKWF DWI I+++++EAPFIP +G GD+SNFDDYEEE +R++ TEKC KEF +F
Sbjct: 17 EISDSFVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF 358
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Celegans
Match: kin-1 (cAMP-dependent protein kinase catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P21137]) HSP 1 Score: 558.525 bits (1438), Expect = 0.000e+0 Identity = 280/359 (77.99%), Postives = 317/359 (88.30%), Query Frame = 1
Query: 70 MIKKLNKVIGNNPNSKKN-DITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
M+K L + +SK N + +K FL++A+ F ++W+ P+QNTA L DF+R++TLGTGSFGRVMLV+HK + Y A+KILDKQKVVKLKQVEHTLNEKRILQAI F FLV + + FKDNSNLYMVLEF++GGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLH LDLIYRDLKPENLLIDS GY+K+TDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKV+FPSHFS +LKDLL+NLLQVDLTKRYGNLKN V DIK HKWF + DWI I++K++EAPF+P +GPGD+SNFDDYEEEPLRI+ TEKC KEFA+F
Sbjct: 1 MLKFLKPKSSDEGSSKDNKNSASLKEFLDKAREDFKQRWENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKIEAPFLPKCRGPGDASNFDDYEEEPLRISGTEKCAKEFAEF 359
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Celegans
Match: kin-1 (cAMP-dependent protein kinase catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P21137]) HSP 1 Score: 556.984 bits (1434), Expect = 0.000e+0 Identity = 276/348 (79.31%), Postives = 313/348 (89.94%), Query Frame = 1
Query: 100 NNPNSKKNDITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
++ ++KK + K FL++A+ F ++W+ P+QNTA L DF+R++TLGTGSFGRVMLV+HK + Y A+KILDKQKVVKLKQVEHTLNEKRILQAI F FLV + + FKDNSNLYMVLEF++GGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLH LDLIYRDLKPENLLIDS GY+K+TDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKV+FPSHFS +LKDLL+NLLQVDLTKRYGNLKN V DIK HKWF + DWI I++K++EAPF+P +GPGD+SNFDDYEEEPLRI+ TEKC KEFA+F
Sbjct: 2 SSSSNKKVQVKFFKEFLDKAREDFKQRWENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKIEAPFLPKCRGPGDASNFDDYEEEPLRISGTEKCAKEFAEF 349
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Celegans
Match: kin-1 (cAMP-dependent protein kinase catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P21137]) HSP 1 Score: 556.984 bits (1434), Expect = 0.000e+0 Identity = 275/339 (81.12%), Postives = 308/339 (90.86%), Query Frame = 1
Query: 127 ITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+ D K FL++A+ F ++W+ P+QNTA L DF+R++TLGTGSFGRVMLV+HK + Y A+KILDKQKVVKLKQVEHTLNEKRILQAI F FLV + + FKDNSNLYMVLEF++GGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLH LDLIYRDLKPENLLIDS GY+K+TDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKV+FPSHFS +LKDLL+NLLQVDLTKRYGNLKN V DIK HKWF + DWI I++K++EAPF+P +GPGD+SNFDDYEEEPLRI+ TEKC KEFA+F
Sbjct: 50 VEDFKEFLDKAREDFKQRWENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKIEAPFLPKCRGPGDASNFDDYEEEPLRISGTEKCAKEFAEF 388
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Celegans
Match: kin-1 (cAMP-dependent protein kinase catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P21137]) HSP 1 Score: 556.599 bits (1433), Expect = 0.000e+0 Identity = 275/336 (81.85%), Postives = 307/336 (91.37%), Query Frame = 1
Query: 136 VKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
VK FL++A+ F ++W+ P+QNTA L DF+R++TLGTGSFGRVMLV+HK + Y A+KILDKQKVVKLKQVEHTLNEKRILQAI F FLV + + FKDNSNLYMVLEF++GGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLH LDLIYRDLKPENLLIDS GY+K+TDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKV+FPSHFS +LKDLL+NLLQVDLTKRYGNLKN V DIK HKWF + DWI I++K++EAPF+P +GPGD+SNFDDYEEEPLRI+ TEKC KEFA+F
Sbjct: 35 VKEFLDKAREDFKQRWENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKIEAPFLPKCRGPGDASNFDDYEEEPLRISGTEKCAKEFAEF 370
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Celegans
Match: kin-1 (cAMP-dependent protein kinase catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P21137]) HSP 1 Score: 555.829 bits (1431), Expect = 0.000e+0 Identity = 274/336 (81.55%), Postives = 307/336 (91.37%), Query Frame = 1
Query: 136 VKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+K FL++A+ F ++W+ P+QNTA L DF+R++TLGTGSFGRVMLV+HK + Y A+KILDKQKVVKLKQVEHTLNEKRILQAI F FLV + + FKDNSNLYMVLEF++GGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLH LDLIYRDLKPENLLIDS GY+K+TDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKV+FPSHFS +LKDLL+NLLQVDLTKRYGNLKN V DIK HKWF + DWI I++K++EAPF+P +GPGD+SNFDDYEEEPLRI+ TEKC KEFA+F
Sbjct: 46 IKEFLDKAREDFKQRWENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKIEAPFLPKCRGPGDASNFDDYEEEPLRISGTEKCAKEFAEF 381
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Fly
Match: Pka-C1 (gene:FBgn0000273 transcript:FBtr0335495) HSP 1 Score: 570.466 bits (1469), Expect = 0.000e+0 Identity = 289/353 (81.87%), Postives = 313/353 (88.67%), Query Frame = 1
Query: 94 IGNNP---NSKKNDITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+GNN N K + VK FLE+AK F +KW + NTA L DFER++TLGTGSFGRVM+VQHK TK+Y A+KILDKQKVVKLKQVEHTLNEKRILQAI F FLV L YHFKDNSNLYMVLE+V GGEMFSHLR++GRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGY+KVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVL+YEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF +DLKDLLRNLLQVDLTKRYGNLK V DIK KWF + DWI IF+K++EAPFIP KGPGD+SNFDDYEEE LRI++TEKC KEFA+F
Sbjct: 1 MGNNATTSNKKVDAAETVKEFLEQAKEEFEDKWRRNPTNTAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPRCKGPGDTSNFDDYEEEALRISSTEKCAKEFAEF 353
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Fly
Match: Pka-C1 (gene:FBgn0000273 transcript:FBtr0079852) HSP 1 Score: 570.466 bits (1469), Expect = 0.000e+0 Identity = 289/353 (81.87%), Postives = 313/353 (88.67%), Query Frame = 1
Query: 94 IGNNP---NSKKNDITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+GNN N K + VK FLE+AK F +KW + NTA L DFER++TLGTGSFGRVM+VQHK TK+Y A+KILDKQKVVKLKQVEHTLNEKRILQAI F FLV L YHFKDNSNLYMVLE+V GGEMFSHLR++GRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGY+KVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVL+YEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF +DLKDLLRNLLQVDLTKRYGNLK V DIK KWF + DWI IF+K++EAPFIP KGPGD+SNFDDYEEE LRI++TEKC KEFA+F
Sbjct: 1 MGNNATTSNKKVDAAETVKEFLEQAKEEFEDKWRRNPTNTAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPRCKGPGDTSNFDDYEEEALRISSTEKCAKEFAEF 353
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Fly
Match: Pka-C1 (gene:FBgn0000273 transcript:FBtr0079851) HSP 1 Score: 570.466 bits (1469), Expect = 0.000e+0 Identity = 289/353 (81.87%), Postives = 313/353 (88.67%), Query Frame = 1
Query: 94 IGNNP---NSKKNDITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+GNN N K + VK FLE+AK F +KW + NTA L DFER++TLGTGSFGRVM+VQHK TK+Y A+KILDKQKVVKLKQVEHTLNEKRILQAI F FLV L YHFKDNSNLYMVLE+V GGEMFSHLR++GRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGY+KVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVL+YEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF +DLKDLLRNLLQVDLTKRYGNLK V DIK KWF + DWI IF+K++EAPFIP KGPGD+SNFDDYEEE LRI++TEKC KEFA+F
Sbjct: 1 MGNNATTSNKKVDAAETVKEFLEQAKEEFEDKWRRNPTNTAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPRCKGPGDTSNFDDYEEEALRISSTEKCAKEFAEF 353
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Fly
Match: Pka-C3 (gene:FBgn0000489 transcript:FBtr0075529) HSP 1 Score: 346.665 bits (888), Expect = 1.036e-115 Identity = 165/314 (52.55%), Postives = 234/314 (74.52%), Query Frame = 1
Query: 208 QLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANT--EKCLKEFADF 1143
L D++ ++T+GTG+FGRV L + +++++Y A+KIL +V++LKQ+EH NE+ IL+ I F++ L++ KD+SNLYM+ ++V GGE+F++LR G+F+ S FYAA+IV A EYLH L ++YRDLKPENLLI+ G++K+TDFGFAK+++ RTWTLCGTPEY+APEII SKG+NKAVDWWALGVLIYEM GYPPF+ +QP IYEKI+SGK+ + H KDL++ LL D TKR GN+KN D+K H+WF + +W ++ K+L+ P +P++ GD+ NFDDY E+ + A ++ L+ F DF
Sbjct: 187 HLDDYQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIRHPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITDFGFAKKLRDRTWTLCGTPEYIAPEIIQSKGHNKAVDWWALGVLIYEMLVGYPPFYDEQPFGIYEKILSGKIEWERHMDPIAKDLIKKLLVNDRTKRLGNMKNGADDVKRHRWFKHLNWNDVYSKKLKPPILPDVHHDGDTKNFDDYPEKDWKPAKAVDQRDLQYFNDF 500
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Fly
Match: Pka-C3 (gene:FBgn0000489 transcript:FBtr0075528) HSP 1 Score: 346.665 bits (888), Expect = 1.316e-114 Identity = 165/314 (52.55%), Postives = 234/314 (74.52%), Query Frame = 1
Query: 208 QLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANT--EKCLKEFADF 1143
L D++ ++T+GTG+FGRV L + +++++Y A+KIL +V++LKQ+EH NE+ IL+ I F++ L++ KD+SNLYM+ ++V GGE+F++LR G+F+ S FYAA+IV A EYLH L ++YRDLKPENLLI+ G++K+TDFGFAK+++ RTWTLCGTPEY+APEII SKG+NKAVDWWALGVLIYEM GYPPF+ +QP IYEKI+SGK+ + H KDL++ LL D TKR GN+KN D+K H+WF + +W ++ K+L+ P +P++ GD+ NFDDY E+ + A ++ L+ F DF
Sbjct: 270 HLDDYQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIRHPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITDFGFAKKLRDRTWTLCGTPEYIAPEIIQSKGHNKAVDWWALGVLIYEMLVGYPPFYDEQPFGIYEKILSGKIEWERHMDPIAKDLIKKLLVNDRTKRLGNMKNGADDVKRHRWFKHLNWNDVYSKKLKPPILPDVHHDGDTKNFDDYPEKDWKPAKAVDQRDLQYFNDF 583
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Match: prkacab (protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b [Source:ZFIN;Acc:ZDB-GENE-040801-208]) HSP 1 Score: 561.607 bits (1446), Expect = 0.000e+0 Identity = 275/351 (78.35%), Postives = 315/351 (89.74%), Query Frame = 1
Query: 94 IGNNPNSKK-NDITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+GN P +K+ N++ VK FL AK F+ KW+ P+QNTA L DF+RL+TLGTGSFGRVMLV+H+ T ++ A+KIL+KQKVVKLKQ+EHTLNEKRILQA++F FLVRL+Y FKDN+NLYMV+++V GGEMFSHLRRIGRFSEPH+RFYA+QIVL FEYLH LDLIYRDLKPENLLID QGYI+VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVL+YEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS+DLKDLLRNLLQVDLTKRYGNLKN V DIK HKWF DWI I+++ +EAPF+P +GPGD+SNFDDYEEE +R++ TEKC KEFA+F
Sbjct: 1 MGNTPAAKRGNEMESVKEFLAFAKEDFLRKWENPAQNTACLEDFDRLKTLGTGSFGRVMLVRHRETGQHYAMKILNKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYSFKDNTNLYMVMQYVQGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLMYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKGHKWFSTTDWIAIYQRRVEAPFVPKCRGPGDTSNFDDYEEEEIRVSFTEKCAKEFAEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Match: prkacaa (protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a [Source:ZFIN;Acc:ZDB-GENE-050114-6]) HSP 1 Score: 560.836 bits (1444), Expect = 0.000e+0 Identity = 279/352 (79.26%), Postives = 316/352 (89.77%), Query Frame = 1
Query: 94 IGNNPNSKK--NDITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+GN P +K N++ VK FL +AK F++KW+ P+QNTA L FERL+TLGTGSFGRVMLV+HK + ++ A+KILDKQKVVKLKQ+EHTLNEKRILQA++F FLVRL++ FKDN+NLYMV+E+V GGEMFSHLRRIGRFSEPH+RFYAAQIVL FEYLH LDLIYRDLKPENLLID QGYI+VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS+DLKDLLRNLLQVDLTKR+GNLKN V DIK HKWF DWI I++K++EAPFIP KGPGD+SNFDDY+EE +R++ TEKC KEFA+F
Sbjct: 1 MGNAPTAKNKGNEMESVKEFLAKAKEDFLKKWENPAQNTASLDHFERLKTLGTGSFGRVMLVKHKESGQHFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEHSFKDNTNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKGHKWFATTDWIAIYQKKVEAPFIPKCKGPGDTSNFDDYDEEEIRVSITEKCGKEFAEF 352
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Match: prkacbb (protein kinase, cAMP-dependent, catalytic, beta b [Source:ZFIN;Acc:ZDB-GENE-050904-4]) HSP 1 Score: 556.214 bits (1432), Expect = 0.000e+0 Identity = 274/351 (78.06%), Postives = 312/351 (88.89%), Query Frame = 1
Query: 94 IGNNPNSKK-NDITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+GN +KK N++ VK FL +AK F+ KW+ P Q+T L DF+R +TLGTGSFGRV+LV+HK + +Y A+K+LDKQKVVKLKQVEHTLNEKRILQA++F FLVRL+Y FKDNSNLYMV+E+V GGEMFSHLRRIGRFSEPH+RFYAAQIVL FEYLH LDLIYRDLKPENLLID GYI+VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS+DLKDLLRNLLQVDLTKR+GNL+N V DIK HKWF DWI I+++++EAPFIP +GPGD+SNFDDYEEE +R++ TEKC KEF++F
Sbjct: 1 MGNAATAKKGNELESVKEFLAKAKEDFLRKWESPQQSTTCLDDFDRQKTLGTGSFGRVLLVKHKASDQYYAMKVLDKQKVVKLKQVEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLRNGVNDIKNHKWFATTDWIAIYERKVEAPFIPKCRGPGDTSNFDDYEEEDIRVSVTEKCAKEFSEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Match: prkacba (protein kinase, cAMP-dependent, catalytic, beta a [Source:ZFIN;Acc:ZDB-GENE-040426-1351]) HSP 1 Score: 522.316 bits (1344), Expect = 0.000e+0 Identity = 256/338 (75.74%), Postives = 301/338 (89.05%), Query Frame = 1
Query: 130 TDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
T +K L +AK F+ KW+ ++TA L DF++L+TLGTGSFGRVMLV+HK +++Y A+KILDK KVVKLKQ+EHTLNEK+ILQA++F FLV+L+ FKDNSNLYMV+ ++ GGEMFSHLRRIGRFSE ++RFYAAQIVL FEYLH LDLIYRDLKPENLLID QGYI+VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVR+PSHFS+DLKDLLRNLLQVDLTKR+GNLKN V DIK H+WF + DWI I++K+++AP IP +GPGD+SNFD+Y+EE +R++ +E+C KEF DF
Sbjct: 58 TAMKETLAKAKEDFLNKWECQQKSTACLDDFDKLKTLGTGSFGRVMLVKHKQSEQYFAMKILDKLKVVKLKQIEHTLNEKKILQAVSFPFLVKLECAFKDNSNLYMVMRYIQGGEMFSHLRRIGRFSEQNARFYAAQIVLTFEYLHMLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRYPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKNHRWFASTDWIAIYEKKVDAPIIPKCRGPGDTSNFDEYDEEVIRVSVSEQCSKEFLDF 395
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Match: prkacba (protein kinase, cAMP-dependent, catalytic, beta a [Source:ZFIN;Acc:ZDB-GENE-040426-1351]) HSP 1 Score: 522.316 bits (1344), Expect = 0.000e+0 Identity = 256/338 (75.74%), Postives = 301/338 (89.05%), Query Frame = 1
Query: 130 TDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
T +K L +AK F+ KW+ ++TA L DF++L+TLGTGSFGRVMLV+HK +++Y A+KILDK KVVKLKQ+EHTLNEK+ILQA++F FLV+L+ FKDNSNLYMV+ ++ GGEMFSHLRRIGRFSE ++RFYAAQIVL FEYLH LDLIYRDLKPENLLID QGYI+VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVR+PSHFS+DLKDLLRNLLQVDLTKR+GNLKN V DIK H+WF + DWI I++K+++AP IP +GPGD+SNFD+Y+EE +R++ +E+C KEF DF
Sbjct: 58 TAMKETLAKAKEDFLNKWECQQKSTACLDDFDKLKTLGTGSFGRVMLVKHKQSEQYFAMKILDKLKVVKLKQIEHTLNEKKILQAVSFPFLVKLECAFKDNSNLYMVMRYIQGGEMFSHLRRIGRFSEQNARFYAAQIVLTFEYLHMLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRYPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKNHRWFASTDWIAIYEKKVDAPIIPKCRGPGDTSNFDEYDEEVIRVSVSEQCSKEFLDF 395
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Match: prkacb (protein kinase cAMP-activated catalytic subunit beta [Source:NCBI gene;Acc:100038053]) HSP 1 Score: 569.311 bits (1466), Expect = 0.000e+0 Identity = 284/351 (80.91%), Postives = 314/351 (89.46%), Query Frame = 1
Query: 94 IGNNPNSKK-NDITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+GN +KK N+I VK FL +AK F+ KW+ P QNTA L DFER++TLGTGSFGRVMLV+HK ++Y A+KILDKQKVVKLKQ+EHTLNEKRILQA+ F FLVRL+Y FKDNSNLYMV+E+V GGEMFSHLRRIGRFSEPH+RFYAAQIVL FEYLH LDLIYRDLKPENLLID QGYI+VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS+DLKDLLRNLLQVDLTKRYGNLKN V DIK HKWF DWI I+++++EAPFIP +GPGD+SNFDDYEEE +R++ TEKC KEFADF
Sbjct: 1 MGNAATAKKGNEIESVKEFLAKAKEDFLRKWETPPQNTASLDDFERIKTLGTGSFGRVMLVKHKGAEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKCRGPGDTSNFDDYEEEDIRVSLTEKCAKEFADF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Match: ints8 (integrator complex subunit 8 [Source:Xenbase;Acc:XB-GENE-980129]) HSP 1 Score: 560.836 bits (1444), Expect = 0.000e+0 Identity = 279/351 (79.49%), Postives = 312/351 (88.89%), Query Frame = 1
Query: 94 IGNNPNSKKN-DITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+GN +KK +I VK FL +AK F++KW+ P+QNTA L FER++TLGTGSFGRVMLV+HK + A+KILDKQKVVKLKQ+EHTLNEKRILQA+ F FLVRL+Y FKDNSNLYMV+E+V GGEMFSHLRRIGRFSEPH+RFYA+QIVL FEYLH LDLIYRDLKPENLLID QGYI+VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS+DLKDLLRNLLQVDLTKR+GNLKN V DIK HKWF DWI +++K++EAPFIP KGPGD+SNFDDYEEE +R++ TEKC KEF+DF
Sbjct: 1 MGNAATAKKGGEIESVKEFLAKAKEDFLKKWENPAQNTAHLEQFERIKTLGTGSFGRVMLVRHKENGSHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVTDIKGHKWFSTTDWIAVYQKKVEAPFIPKCKGPGDTSNFDDYEEEEIRVSITEKCAKEFSDF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Match: ints8 (integrator complex subunit 8 [Source:Xenbase;Acc:XB-GENE-980129]) HSP 1 Score: 554.673 bits (1428), Expect = 0.000e+0 Identity = 274/339 (80.83%), Postives = 306/339 (90.27%), Query Frame = 1
Query: 127 ITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
++ VK FL +AK F++KW+ P+QNTA L FER++TLGTGSFGRVMLV+HK + A+KILDKQKVVKLKQ+EHTLNEKRILQA+ F FLVRL+Y FKDNSNLYMV+E+V GGEMFSHLRRIGRFSEPH+RFYA+QIVL FEYLH LDLIYRDLKPENLLID QGYI+VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS+DLKDLLRNLLQVDLTKR+GNLKN V DIK HKWF DWI +++K++EAPFIP KGPGD+SNFDDYEEE +R++ TEKC KEF+DF
Sbjct: 30 LSTVKEFLAKAKEDFLKKWENPAQNTAHLEQFERIKTLGTGSFGRVMLVRHKENGSHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVTDIKGHKWFSTTDWIAVYQKKVEAPFIPKCKGPGDTSNFDDYEEEEIRVSITEKCAKEFSDF 368
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Match: ints8 (integrator complex subunit 8 [Source:Xenbase;Acc:XB-GENE-980129]) HSP 1 Score: 554.288 bits (1427), Expect = 0.000e+0 Identity = 274/336 (81.55%), Postives = 304/336 (90.48%), Query Frame = 1
Query: 136 VKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
VK FL +AK F++KW+ P+QNTA L FER++TLGTGSFGRVMLV+HK + A+KILDKQKVVKLKQ+EHTLNEKRILQA+ F FLVRL+Y FKDNSNLYMV+E+V GGEMFSHLRRIGRFSEPH+RFYA+QIVL FEYLH LDLIYRDLKPENLLID QGYI+VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS+DLKDLLRNLLQVDLTKR+GNLKN V DIK HKWF DWI +++K++EAPFIP KGPGD+SNFDDYEEE +R++ TEKC KEF+DF
Sbjct: 2 VKEFLAKAKEDFLKKWENPAQNTAHLEQFERIKTLGTGSFGRVMLVRHKENGSHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVTDIKGHKWFSTTDWIAVYQKKVEAPFIPKCKGPGDTSNFDDYEEEEIRVSITEKCAKEFSDF 337
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Match: ints8 (integrator complex subunit 8 [Source:Xenbase;Acc:XB-GENE-980129]) HSP 1 Score: 554.288 bits (1427), Expect = 0.000e+0 Identity = 273/337 (81.01%), Postives = 305/337 (90.50%), Query Frame = 1
Query: 133 DVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
++K FL +AK F++KW+ P+QNTA L FER++TLGTGSFGRVMLV+HK + A+KILDKQKVVKLKQ+EHTLNEKRILQA+ F FLVRL+Y FKDNSNLYMV+E+V GGEMFSHLRRIGRFSEPH+RFYA+QIVL FEYLH LDLIYRDLKPENLLID QGYI+VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS+DLKDLLRNLLQVDLTKR+GNLKN V DIK HKWF DWI +++K++EAPFIP KGPGD+SNFDDYEEE +R++ TEKC KEF+DF
Sbjct: 21 NMKEFLAKAKEDFLKKWENPAQNTAHLEQFERIKTLGTGSFGRVMLVRHKENGSHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVTDIKGHKWFSTTDWIAVYQKKVEAPFIPKCKGPGDTSNFDDYEEEEIRVSITEKCAKEFSDF 357
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Mouse
Match: Prkacb (protein kinase, cAMP dependent, catalytic, beta [Source:MGI Symbol;Acc:MGI:97594]) HSP 1 Score: 554.288 bits (1427), Expect = 0.000e+0 Identity = 277/351 (78.92%), Postives = 311/351 (88.60%), Query Frame = 1
Query: 94 IGNNPNSKK-NDITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+GN +KK +++ VK FL +AK F+ KW+ P + A L DFER +TLGTGSFGRVMLV+HK T++Y A+KILDKQKVVKLKQ+EHTLNEKRILQA+ F FLVRL+Y FKDNSNLYMV+E+V GGEMFSHLRRIGRFSEPH+RFYAAQIVL FEYLH LDLIYRDLKPENLLID QGYI+VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS+DLKDLLRNLLQVDLTKR+GNLKN V DIKTHKWF DWI I+++++EAPFIP +G GD+SNFDDYEEE +R++ TEKC KEF +F
Sbjct: 1 MGNTAIAKKGSEVESVKEFLAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEEIRVSITEKCGKEFCEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Mouse
Match: Prkaca (protein kinase, cAMP dependent, catalytic, alpha [Source:MGI Symbol;Acc:MGI:97592]) HSP 1 Score: 554.288 bits (1427), Expect = 0.000e+0 Identity = 276/351 (78.63%), Postives = 312/351 (88.89%), Query Frame = 1
Query: 94 IGNNPNSKK-NDITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+GN +KK ++ VK FL +AK F++KW+ PSQNTAQL F+R++TLGTGSFGRVMLV+HK + + A+KILDKQKVVKLKQ+EHTLNEKRILQA+ F FLV+L++ FKDNSNLYMV+E+V GGEMFSHLRRIGRFSEPH+RFYAAQIVL FEYLH LDLIYRDLKPENLLID QGYI+VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS+DLKDLLRNLLQVDLTKR+GNLKN V DIK HKWF DWI I+++++EAPFIP KGPGD+SNFDDYEEE +R++ EKC KEF +F
Sbjct: 1 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Mouse
Match: Prkaca (protein kinase, cAMP dependent, catalytic, alpha [Source:MGI Symbol;Acc:MGI:97592]) HSP 1 Score: 553.518 bits (1425), Expect = 0.000e+0 Identity = 273/338 (80.77%), Postives = 305/338 (90.24%), Query Frame = 1
Query: 130 TDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
DVK FL +AK F++KW+ PSQNTAQL F+R++TLGTGSFGRVMLV+HK + + A+KILDKQKVVKLKQ+EHTLNEKRILQA+ F FLV+L++ FKDNSNLYMV+E+V GGEMFSHLRRIGRFSEPH+RFYAAQIVL FEYLH LDLIYRDLKPENLLID QGYI+VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS+DLKDLLRNLLQVDLTKR+GNLKN V DIK HKWF DWI I+++++EAPFIP KGPGD+SNFDDYEEE +R++ EKC KEF +F
Sbjct: 6 NDVKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 343
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Mouse
Match: Prkacb (protein kinase, cAMP dependent, catalytic, beta [Source:MGI Symbol;Acc:MGI:97594]) HSP 1 Score: 548.895 bits (1413), Expect = 0.000e+0 Identity = 272/336 (80.95%), Postives = 302/336 (89.88%), Query Frame = 1
Query: 136 VKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+K FL +AK F+ KW+ P + A L DFER +TLGTGSFGRVMLV+HK T++Y A+KILDKQKVVKLKQ+EHTLNEKRILQA+ F FLVRL+Y FKDNSNLYMV+E+V GGEMFSHLRRIGRFSEPH+RFYAAQIVL FEYLH LDLIYRDLKPENLLID QGYI+VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS+DLKDLLRNLLQVDLTKR+GNLKN V DIKTHKWF DWI I+++++EAPFIP +G GD+SNFDDYEEE +R++ TEKC KEF +F
Sbjct: 63 MKEFLAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEEIRVSITEKCGKEFCEF 398
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Mouse
Match: Prkacb (protein kinase, cAMP dependent, catalytic, beta [Source:MGI Symbol;Acc:MGI:97594]) HSP 1 Score: 548.51 bits (1412), Expect = 0.000e+0 Identity = 273/337 (81.01%), Postives = 303/337 (89.91%), Query Frame = 1
Query: 133 DVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+VK FL +AK F+ KW+ P + A L DFER +TLGTGSFGRVMLV+HK T++Y A+KILDKQKVVKLKQ+EHTLNEKRILQA+ F FLVRL+Y FKDNSNLYMV+E+V GGEMFSHLRRIGRFSEPH+RFYAAQIVL FEYLH LDLIYRDLKPENLLID QGYI+VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS+DLKDLLRNLLQVDLTKR+GNLKN V DIKTHKWF DWI I+++++EAPFIP +G GD+SNFDDYEEE +R++ TEKC KEF +F
Sbjct: 2 NVKEFLAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEEIRVSITEKCGKEFCEF 338
BLAST of cAMP-dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Match: sp|P12370|KAPC1_DROME (cAMP-dependent protein kinase catalytic subunit 1 OS=Drosophila melanogaster OX=7227 GN=Pka-C1 PE=1 SV=3) HSP 1 Score: 570.466 bits (1469), Expect = 0.000e+0 Identity = 289/353 (81.87%), Postives = 313/353 (88.67%), Query Frame = 1
Query: 94 IGNNP---NSKKNDITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+GNN N K + VK FLE+AK F +KW + NTA L DFER++TLGTGSFGRVM+VQHK TK+Y A+KILDKQKVVKLKQVEHTLNEKRILQAI F FLV L YHFKDNSNLYMVLE+V GGEMFSHLR++GRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGY+KVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVL+YEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF +DLKDLLRNLLQVDLTKRYGNLK V DIK KWF + DWI IF+K++EAPFIP KGPGD+SNFDDYEEE LRI++TEKC KEFA+F
Sbjct: 1 MGNNATTSNKKVDAAETVKEFLEQAKEEFEDKWRRNPTNTAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPRCKGPGDTSNFDDYEEEALRISSTEKCAKEFAEF 353
BLAST of cAMP-dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Match: sp|P22694|KAPCB_HUMAN (cAMP-dependent protein kinase catalytic subunit beta OS=Homo sapiens OX=9606 GN=PRKACB PE=1 SV=2) HSP 1 Score: 561.992 bits (1447), Expect = 0.000e+0 Identity = 279/351 (79.49%), Postives = 314/351 (89.46%), Query Frame = 1
Query: 94 IGNNPNSKK-NDITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+GN +KK +++ VK FL +AK F++KW+ P+QN A L DFER +TLGTGSFGRVMLV+HK T++Y A+KILDKQKVVKLKQ+EHTLNEKRILQA+ F FLVRL+Y FKDNSNLYMV+E+V GGEMFSHLRRIGRFSEPH+RFYAAQIVL FEYLH LDLIYRDLKPENLLID QGYI+VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS+DLKDLLRNLLQVDLTKR+GNLKN V DIKTHKWF DWI I+++++EAPFIP +G GD+SNFDDYEEE +R++ TEKC KEF +F
Sbjct: 1 MGNAATAKKGSEVESVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Match: sp|P05131|KAPCB_BOVIN (cAMP-dependent protein kinase catalytic subunit beta OS=Bos taurus OX=9913 GN=PRKACB PE=1 SV=2) HSP 1 Score: 557.755 bits (1436), Expect = 0.000e+0 Identity = 278/351 (79.20%), Postives = 313/351 (89.17%), Query Frame = 1
Query: 94 IGNNPNSKK-NDITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+GN +KK +++ VK FL +AK F++KW+ P+ N A L DFER +TLGTGSFGRVMLV+HK T++Y A+KILDKQKVVKLKQ+EHTLNEKRILQA+ F FLVRL+Y FKDNSNLYMV+E+V GGEMFSHLRRIGRFSEPH+RFYAAQIVL FEYLH LDLIYRDLKPENLLID QGYI+VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS+DLKDLLRNLLQVDLTKR+GNLKN V DIKTHKWF DWI I+++++EAPFIP +G GD+SNFDDYEEE +R++ TEKC KEF +F
Sbjct: 1 MGNAATAKKGSEVESVKEFLAKAKEDFLKKWENPAPNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCGKEFCEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Match: sp|P05383|KAPCB_PIG (cAMP-dependent protein kinase catalytic subunit beta OS=Sus scrofa OX=9823 GN=PRKACB PE=1 SV=3) HSP 1 Score: 556.599 bits (1433), Expect = 0.000e+0 Identity = 277/351 (78.92%), Postives = 313/351 (89.17%), Query Frame = 1
Query: 94 IGNNPNSKK-NDITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+GN +KK +++ VK FL +AK F++KW+ P+ N A L DFER +TLGTGSFGRVMLV+HK T++Y A+KILDKQKVVKLKQ+EHTLNEKRILQA+ F FLVRL++ FKDNSNLYMV+E+V GGEMFSHLRRIGRFSEPH+RFYAAQIVL FEYLH LDLIYRDLKPENLLID QGYI+VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS+DLKDLLRNLLQVDLTKR+GNLKN V DIKTHKWF DWI I+++++EAPFIP +G GD+SNFDDYEEE +R++ TEKC KEF +F
Sbjct: 1 MGNAATAKKGSEVESVKEFLAKAKEDFLKKWENPAPNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCGKEFCEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Match: sp|P36887|KAPCA_PIG (cAMP-dependent protein kinase catalytic subunit alpha OS=Sus scrofa OX=9823 GN=PRKACA PE=1 SV=4) HSP 1 Score: 555.058 bits (1429), Expect = 0.000e+0 Identity = 277/351 (78.92%), Postives = 312/351 (88.89%), Query Frame = 1
Query: 94 IGNNPNSKK-NDITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+GN +KK ++ VK FL +AK F++KW+ P+QNTA L FER++TLGTGSFGRVMLV+HK T + A+KILDKQKVVKLKQ+EHTLNEKRILQA+ F FLV+L+Y FKDNSNLYMV+E+V GGEMFSHLRRIGRFSEPH+RFYAAQIVL FEYLH LDLIYRDLKPENLLID QGYI+VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS+DLKDLLRNLLQVDLTKR+GNLKN V DIK HKWF DWI I+++++EAPFIP KGPGD+SNFDDYEEE +R++ EKC KEF++F
Sbjct: 1 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. TrEMBL
Match: A0A267E1M0 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig020537g1 PE=3 SV=1) HSP 1 Score: 600.127 bits (1546), Expect = 0.000e+0 Identity = 301/353 (85.27%), Postives = 323/353 (91.50%), Query Frame = 1
Query: 85 NKVIGNNPNSKKNDITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
NK + P SKK DITD K++LEEAK+ F +KWD+P QNTA L DFER+RTLGTGSFGRVMLVQHK KE+ A+KILDKQKVVKLKQVEHTLNEKRILQAITF FLVRLDYHFKDNSNLYM+LEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVL FEYLH LDLIYRDLKPENLL+D+ GYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVL+YEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS+DLKDLLRNLLQVDLTKR+GNLKN V DIK+HKWF DWI ++KKE+EAPF+P KGPGD SNFD+YEEEPLRIA TEKC KEFA+F
Sbjct: 6 NKFSSSAP-SKKGDITDFKSYLEEAKKDFQDKWDRPGQNTASLDDFERIRTLGTGSFGRVMLVQHKQRKEFYAMKILDKQKVVKLKQVEHTLNEKRILQAITFPFLVRLDYHFKDNSNLYMILEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLGFEYLHSLDLIYRDLKPENLLLDAVGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKSHKWFATTDWIQVYKKEVEAPFVPKSKGPGDPSNFDEYEEEPLRIAGTEKCAKEFAEF 357
BLAST of cAMP-dependent protein kinase catalytic subunit vs. TrEMBL
Match: A0A1S3JH22 (cAMP-dependent protein kinase catalytic subunit isoform X11 OS=Lingula unguis OX=7574 GN=LOC106173017 PE=3 SV=1) HSP 1 Score: 594.734 bits (1532), Expect = 0.000e+0 Identity = 297/351 (84.62%), Postives = 322/351 (91.74%), Query Frame = 1
Query: 94 IGNNPNSKKND-ITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+GN +KK D +VKAFL +AK F +KW+KPSQNTA L DFER++TLGTGSFGRVMLVQHK +K+Y A+KILDKQKVVKLKQVEHTLNEKRILQA++F FLV L+YHFKDNSNLYMVLEFV GGEMFSHLRRIGRFSEPH+RFYAAQIVLAFEYLHYLDL+YRDLKPENLLIDS GYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVL+YEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS+DLKDLLRNLLQVDLTKRYGNLKN V DIK HKWF DWI I++K++EAPFIP KGPGD+SNFDDYEEEPLRI++TEKC KEFADF
Sbjct: 1 MGNAQTAKKLDPAENVKAFLAQAKAEFSDKWEKPSQNTAGLDDFERIKTLGTGSFGRVMLVQHKQSKQYYAMKILDKQKVVKLKQVEHTLNEKRILQAVSFPFLVSLEYHFKDNSNLYMVLEFVTGGEMFSHLRRIGRFSEPHARFYAAQIVLAFEYLHYLDLVYRDLKPENLLIDSMGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKNHKWFATTDWIAIYQKKVEAPFIPKCKGPGDASNFDDYEEEPLRISSTEKCAKEFADF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. TrEMBL
Match: A0A267E497 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig032677g1 PE=3 SV=1) HSP 1 Score: 592.808 bits (1527), Expect = 0.000e+0 Identity = 292/350 (83.43%), Postives = 324/350 (92.57%), Query Frame = 1
Query: 94 IGNNPNSKKNDITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+GN SKK+D +DVKAFLEEAK+ F EKWD+P+QNTAQL DF+R+RTLGTGSFGRVMLVQHK K++ A+KILDKQKVVKLKQ+EHTLNEKRILQAI+F FLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSE SR Y AQIVLAFEYLH+LDL+YRDLKPEN+LI++ G++KVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVL+YEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS+DLKDLLRNLLQVDLTKR+GNLKN V DIK+HKWF DWI ++KKE+EAPF+P KGPGD SNFD+YEEEPLRIA++EKC KEFA+F
Sbjct: 7 LGNTQQSKKSDPSDVKAFLEEAKKDFQEKWDRPAQNTAQLDDFDRIRTLGTGSFGRVMLVQHKQKKDFYAMKILDKQKVVKLKQIEHTLNEKRILQAISFPFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEDVSRLYGAQIVLAFEYLHHLDLVYRDLKPENILINADGFLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKSHKWFATTDWIQVYKKEVEAPFVPKSKGPGDPSNFDEYEEEPLRIASSEKCAKEFAEF 356
BLAST of cAMP-dependent protein kinase catalytic subunit vs. TrEMBL
Match: D2JWR5 (cAMP-dependent protein kinase catalytic subunit OS=Schistosoma japonicum OX=6182 GN=EWB00_007721 PE=2 SV=1) HSP 1 Score: 592.423 bits (1526), Expect = 0.000e+0 Identity = 290/350 (82.86%), Postives = 321/350 (91.71%), Query Frame = 1
Query: 94 IGNNPNSKKNDITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+GN +KK D DVKA LEEAK+ F+EKW+KP+QNTA L F+R++TLGTGSFGRVMLVQHKV+KEY A+KILDKQKVVKLKQVEHTLNEKRILQAI+F FLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSE HSRFYA+Q+VLAFEYLH+L+L+YRDLKPEN+LID GY+K+TDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVL+YEMAAGYPPFFADQPIQIYE+IVSGKVRFPSHFS+DLKDLLRNLLQVDLTKR+GNLKN V DIKTHKWF DW +IFK+++EAPF P G GD+SNFDDYEEEPLRIA TEKC KEF++F
Sbjct: 1 MGNAQTAKKGDPADVKALLEEAKKEFLEKWEKPAQNTATLDSFDRIKTLGTGSFGRVMLVQHKVSKEYYAMKILDKQKVVKLKQVEHTLNEKRILQAISFPFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHSRFYASQVVLAFEYLHHLELVYRDLKPENILIDQYGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYERIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKTHKWFATTDWFSIFKRDIEAPFTPKCSGAGDASNFDDYEEEPLRIATTEKCAKEFSEF 350
BLAST of cAMP-dependent protein kinase catalytic subunit vs. TrEMBL
Match: D2JVC2 (cAMP-dependent protein kinase catalytic subunit OS=Schistosoma haematobium OX=6185 PE=2 SV=1) HSP 1 Score: 592.038 bits (1525), Expect = 0.000e+0 Identity = 289/350 (82.57%), Postives = 320/350 (91.43%), Query Frame = 1
Query: 94 IGNNPNSKKNDITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+GN +KK D DVKA LEEAK+ F+EKW+KP+QNTA L F+R++TLGTGSFGRVMLVQHKV+KEY A+K LDKQKVVKLKQVEHTLNEKRILQAI+F FLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSE HSRFYA+Q+VLAFEYLH+L+L+YRDLKPEN+LID GY+K+TDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVL+YEMAAGYPPFFADQPIQIYE+IVSGKVRFPSHFS+DLKDLLRNLLQVDLTKR+GNLKN V DIKTHKWF DW +IFK+++EAPF P G GD+SNFDDYEEEPLRIA TEKC KEF++F
Sbjct: 1 MGNAQAAKKGDPADVKALLEEAKKEFLEKWEKPAQNTATLDSFDRIKTLGTGSFGRVMLVQHKVSKEYYAMKTLDKQKVVKLKQVEHTLNEKRILQAISFPFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHSRFYASQVVLAFEYLHHLELVYRDLKPENVLIDQYGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYERIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKTHKWFATTDWFSIFKRDIEAPFTPKCSGAGDASNFDDYEEEPLRIATTEKCAKEFSEF 350
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Match: prkacaa (cAMP-dependent protein kinase catalytic subunit alpha [Source:NCBI gene;Acc:103024963]) HSP 1 Score: 564.688 bits (1454), Expect = 0.000e+0 Identity = 281/352 (79.83%), Postives = 316/352 (89.77%), Query Frame = 1
Query: 94 IGNNPNSKK--NDITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+GN P +K N++ VK FL +AK F++KW+ P+QNTA L FERL+TLGTGSFGRVMLV+HK T ++ A+KILDKQKVVKLKQ+EHTLNEKRILQA++F FLVRL++ FKDNSNLYMV+E+V GGEMFSHLRRIGRFSEPH+RFYAAQIVL FEYLH LDLIYRDLKPENLLID QGYI+VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS+DLKDLLRNLLQVDLTKR+GNLKN V DIK HKWF DWI I+++++EAPFIP KGPGD+SNFDDYEEE +R++ TEKC KEFA+F
Sbjct: 1 MGNAPTAKNKGNEMESVKEFLAKAKEDFLKKWENPAQNTASLDQFERLKTLGTGSFGRVMLVKHKETGQHFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEHSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKGHKWFATTDWIAIYQRKVEAPFIPKCKGPGDTSNFDDYEEEEIRVSFTEKCGKEFAEF 352
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Match: prkacbb (cAMP-dependent protein kinase catalytic subunit beta [Source:NCBI gene;Acc:103034112]) HSP 1 Score: 560.451 bits (1443), Expect = 0.000e+0 Identity = 278/351 (79.20%), Postives = 313/351 (89.17%), Query Frame = 1
Query: 94 IGNNPNSKK-NDITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+GN +KK N++ VK FL +AK F+ KW+ P Q+T L DFERL+TLGTGSFGRVMLV+HK T+++ A+K+LDKQKVVKLKQ+EHTLNEKRILQA++F FLVRL+Y FKDNSNLYMV+E+V GGEMFSHLRRIGRFSEPH+RFYAAQIVL FEYLH LDLIYRDLKPENLLID GYI+VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS+DLKDLLRNLLQVDLTKRYGNLKN V DIK HKWF DWI I+++++EAPFIP +GPGD+SNFDDYEEE +R++ TEKC KEF +F
Sbjct: 1 MGNAAAAKKGNELESVKEFLAKAKEDFLRKWECPPQSTTTLDDFERLKTLGTGSFGRVMLVKHKGTEQFFAMKVLDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKNHKWFATTDWIAIYERKVEAPFIPKCRGPGDTSNFDDYEEEDIRVSVTEKCAKEFTEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Match: prkacaa (cAMP-dependent protein kinase catalytic subunit alpha [Source:NCBI gene;Acc:103024963]) HSP 1 Score: 559.681 bits (1441), Expect = 0.000e+0 Identity = 277/339 (81.71%), Postives = 309/339 (91.15%), Query Frame = 1
Query: 127 ITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+ DVK FL +AK F++KW+ P+QNTA L FERL+TLGTGSFGRVMLV+HK T ++ A+KILDKQKVVKLKQ+EHTLNEKRILQA++F FLVRL++ FKDNSNLYMV+E+V GGEMFSHLRRIGRFSEPH+RFYAAQIVL FEYLH LDLIYRDLKPENLLID QGYI+VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS+DLKDLLRNLLQVDLTKR+GNLKN V DIK HKWF DWI I+++++EAPFIP KGPGD+SNFDDYEEE +R++ TEKC KEFA+F
Sbjct: 81 LVDVKEFLAKAKEDFLKKWENPAQNTASLDQFERLKTLGTGSFGRVMLVKHKETGQHFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEHSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKGHKWFATTDWIAIYQRKVEAPFIPKCKGPGDTSNFDDYEEEEIRVSFTEKCGKEFAEF 419
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Match: ENSAMXT00000050353.1 (protein kinase cAMP-activated catalytic subunit beta [Source:NCBI gene;Acc:103029308]) HSP 1 Score: 556.599 bits (1433), Expect = 0.000e+0 Identity = 278/351 (79.20%), Postives = 312/351 (88.89%), Query Frame = 1
Query: 94 IGNNPNSKK-NDITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+GN +KK N++ VK FL +AK F+ KW+ P Q+T L DFERL+TLGTGSFGRVMLV+HK T++Y A+KILDKQKVVKLKQ+EHTLNEKRILQA++F FLVRL+Y FKDNSNLYMV+E+V GGEMFSHLRRIGRFSE H+RFYAAQIVL FEYLH LDLIYRDLKPENLLID GYI+VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS+DLKDLLRNLLQVDLTKR+GNLKN V DIK HKWF DWI I+++++EAP IP +GPGD+SNFDDYEEE +RI++TEKC KEF +F
Sbjct: 1 MGNAAAAKKGNELESVKEFLAKAKEDFLRKWECPPQSTTCLDDFERLKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEHHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYERKVEAPIIPKCRGPGDTSNFDDYEEEEIRISDTEKCAKEFLEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Match: prkacab (cAMP-dependent protein kinase catalytic subunit alpha [Source:NCBI gene;Acc:103023241]) HSP 1 Score: 550.821 bits (1418), Expect = 0.000e+0 Identity = 270/351 (76.92%), Postives = 311/351 (88.60%), Query Frame = 1
Query: 94 IGNNPNSKK-NDITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+GN P +K+ N++ V+ FL A+ F+ KW+ P+QNTA L F+ L+TLGTGSFGRVMLV+H+ ++ A+KIL+KQKVVKLKQ+EHTLNEKRILQA++F FLV+L+Y FKDNSNLYMV+E+V GGEMFSHLRRIGRFSEPH+RFYA+QIVL FEYLH LDLIYRDLKPENLLID QGYI+VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVL+YEMAAGYPPFFADQPI IYEKIVSGKVRFPSHFS+DLK+LLRNLLQVDLTKRYGNLKN V DIK HKWF DWI I+++ +EAPFIP +GPGD+SNFDDYEEE +R++ TEKC KEFA+F
Sbjct: 1 MGNTPAAKRGNEMESVREFLALAREDFLRKWETPAQNTASLDQFDLLKTLGTGSFGRVMLVRHRENGQHYAMKILNKQKVVKLKQIEHTLNEKRILQAVSFPFLVQLEYSFKDNSNLYMVMEYVQGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIHIYEKIVSGKVRFPSHFSSDLKELLRNLLQVDLTKRYGNLKNGVNDIKGHKWFSTTDWIAIYQRRVEAPFIPKCRGPGDTSNFDDYEEEEIRVSLTEKCGKEFAEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001814.1 (pep scaffold:Pmarinus_7.0:GL481074:830:17391:1 gene:ENSPMAG00000001637.1 transcript:ENSPMAT00000001814.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 499.59 bits (1285), Expect = 1.309e-179 Identity = 235/266 (88.35%), Postives = 250/266 (93.98%), Query Frame = 1
Query: 346 VEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
VEHTLNEKRILQAI+F FLVRL+Y FKDNSNLYMVLE+V GGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLH LDLIYRDLKPENLLID QGYI+VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS+DLKDLLRNLLQVDLTKR+GNLKN V DIK HKWF DWI I+++++EAPFIP KGPGD+SNFDDYEEE +RI++TEKC KEFADF
Sbjct: 23 VEHTLNEKRILQAISFPFLVRLEYSFKDNSNLYMVLEYVPGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFSTTDWIAIYQRKVEAPFIPKCKGPGDASNFDDYEEEEIRISSTEKCAKEFADF 288
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004852.1 (pep scaffold:Pmarinus_7.0:GL488704:3417:7135:1 gene:ENSPMAG00000004407.1 transcript:ENSPMAT00000004852.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 251.521 bits (641), Expect = 1.692e-83 Identity = 138/179 (77.09%), Postives = 153/179 (85.47%), Query Frame = 1
Query: 103 NPNSKKNDITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKV 639
+P I VK FL +AK F++KW+ P QNT+ L DFER++TLGTGSFGRVMLV+HK T Y A+KILDKQKVVKLKQVEHTLNEKRILQAI+F FLV L+Y +KDNSNLYMVLE+V GGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLH LDLIYRDLKPENLLID QGYI+V
Sbjct: 5 SPAVSAMCIFAVKEFLAKAKEDFLKKWENPQQNTSCLDDFERMKTLGTGSFGRVMLVKHKATDRYFAMKILDKQKVVKLKQVEHTLNEKRILQAISFPFLVSLEYSYKDNSNLYMVLEYVPGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDQQGYIQV 183
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002200.1 (pep scaffold:Pmarinus_7.0:GL479132:31244:36905:-1 gene:ENSPMAG00000001993.1 transcript:ENSPMAT00000002200.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 249.21 bits (635), Expect = 2.252e-80 Identity = 128/292 (43.84%), Postives = 189/292 (64.73%), Query Frame = 1
Query: 229 LRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG--KVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEE 1092
+ TLG G FGRV LV+ K + A+K L K+ VV+ +Q EH +EKRILQ + F+VR F+D +++++E GGE++S LR G F E +RF A +V A YLH ++YRDLKPENLL+D++GYIK+ DFGFAK++ + WT CGTPEY+ PE+I+++G+++ D WALGVL+YE+ AG PPF P++ Y I+ G +V FP+ +D++R L + + ++R GN K+ VGD++ HKWF DW ++ +L +P + GP D NFD + E+
Sbjct: 37 IATLGVGGFGRVQLVKLKDSDVTFALKCLKKKFVVESRQQEHVYSEKRILQECSCPFIVRFYRTFRDQKFVFLLMEACLGGELWSVLRDSGGFQEVSARFCVACVVEALAYLHARGILYRDLKPENLLLDARGYIKMADFGFAKKLACGRKAWTFCGTPEYVCPEMIVNRGHDRGADCWALGVLVYELLAGVPPFSGTDPMKTYNAILWGMERVHFPNEVGKRAEDIIRRLCRQNPSERLGNQKHGVGDVRKHKWFQGFDWESLRSNQLASPLKREVSGPTDFKNFDWFPED 328
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008480.1 (pep scaffold:Pmarinus_7.0:GL482122:191709:206473:1 gene:ENSPMAG00000007654.1 transcript:ENSPMAT00000008480.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 234.572 bits (597), Expect = 4.960e-73 Identity = 127/302 (42.05%), Postives = 185/302 (61.26%), Query Frame = 1
Query: 187 KPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHY-LDLIYRDLKPENLLIDSQGYIKVTDFGFAKR--VKGRTW-TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDD 1080
KP ++ +++F+ L+ LG G+FG+V+LV+ K T +Y A+KIL K+ +V +V HTL E R+LQ FL L Y F+ + L V+E+VNGGE+F HL R FSE +RFY A+IV A +YLH +++YRDLK ENL++D G+IK+ DFG K G T T CGTPEYLAPE++ Y +AVDWW LGV++YEM G PF+ +++E I+ +RFP S D + LL LL+ D +R G ++ +I H +F W ++ +++ PF P + D+ FD+
Sbjct: 140 KP-KSKVTMNNFDYLKLLGKGTFGKVILVREKATGQYYAMKILKKEVIVAKDEVAHTLTENRVLQTTKHPFLTLLKYSFQTHDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHTEKNVVYRDLKLENLMLDKDGHIKIADFGLCKEGITDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIRFPRTLSNDARALLSGLLKKDPKQRLGGGVDDAKEIMRHSFFAGIIWQDVYDRKMTPPFKPQVASETDTRYFDE 440
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006766.1 (pep scaffold:Pmarinus_7.0:GL478342:9725:27922:-1 gene:ENSPMAG00000006086.1 transcript:ENSPMAT00000006766.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 232.646 bits (592), Expect = 5.713e-73 Identity = 127/312 (40.71%), Postives = 191/312 (61.22%), Query Frame = 1
Query: 190 PSQN-TAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRIL-QAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKR---VKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDD-YEEEPLRIA 1107
PS N A+ SDF+ L LG GSFG+V+L +HK + A+K++ K +++ K+ +H + E+ +L + + FLV L Y F+ LY V+++VNGGE+F HL+R G F E ++FYAA+I A YLH L+++YRDLKPEN+L+D QG+I +TDFG K T T CGTPEYLAPE++ Y++ VDWW LG ++YEM G PPF++ Q+YE I+ ++ + +L LL D +R G +++ +IK H +F +W + K + +P+ P + GP D NFD + EPL ++
Sbjct: 81 PSANLQAKPSDFDFLTVLGKGSFGKVLLAKHKSDGIFYAVKVMKKSIILQKKEEKHIMAERNVLVKNVRHPFLVGLHYSFQSADKLYFVMDYVNGGELFFHLQRQGSFPESRAQFYAAEIGSAIGYLHSLNIVYRDLKPENILLDYQGHIVLTDFGLCKEGIDPHSTTCTFCGTPEYLAPEVLKKHPYDRTVDWWCLGCVLYEMLYGLPPFYSKNLKQMYESILHQPLQLRPCTTNAAISVLEGLLHKDPHQRLG-ATSDILEIKNHVFFSTINWNDLDAKRIPSPYNPGVSGPCDLHNFDPAFTAEPLSMS 391
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Yeast
Match: TPK2 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]) HSP 1 Score: 322.398 bits (825), Expect = 1.223e-108 Identity = 168/320 (52.50%), Postives = 227/320 (70.94%), Query Frame = 1
Query: 193 SQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNI-KGPGDSSNFDDYEEEPLR--IANTEKCLKEFADF 1143
S+ L DF+ +RTLGTGSFGRV LV+ Y AIK+L KQ+VVK+KQVEHT +E+R+L+ + FL+R+ F+D N++MV++++ GGE+FS LR+ RF P ++FYAA+++LA EYLH ++IYRDLKPEN+L+D G+IK+TDFGFAK V+ TWTLCGTP+Y+APE+I +K YNK+VDWW+LGVLIYEM AGY PF+ P++ YEKI+ GKV +P +F D+ DLL L+ DLT+R GNL++ DIK H WF W + K++E P+ P I G GD+S FD Y EE L I + + F DF
Sbjct: 61 SKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVDLLSKLITADLTRRIGNLQSGSRDIKAHPWFSEVVWERLLAKDIETPYEPPITSGIGDTSLFDQYPEEQLDYGIQGDDPYAEYFQDF 380
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Yeast
Match: TPK1 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]) HSP 1 Score: 309.686 bits (792), Expect = 1.761e-103 Identity = 150/297 (50.51%), Postives = 215/297 (72.39%), Query Frame = 1
Query: 211 LSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNI-KGPGDSSNFDDYEEEPL 1098
L DF+ LRTLGTGSFGRV L++ + Y A+K+L K+ VV+LKQVEHT +E+ +L +T F++R+ F+D ++M+++++ GGE+FS LR+ RF P ++FYAA++ LA EYLH D+IYRDLKPEN+L+D G+IK+TDFGFAK V T+TLCGTP+Y+APE++ +K YNK++DWW+ G+LIYEM AGY PF+ ++ YEKI++ ++RFP F+ D+KDLL L+ DL++R GNL+N D+K H WF W + + +E P+ P I +G GD+S FD Y EE +
Sbjct: 84 LQDFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFFNEDVKDLLSRLITRDLSQRLGNLQNGTEDVKNHPWFKEVVWEKLLSRNIETPYEPPIQQGQGDTSQFDKYPEEDI 380
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Yeast
Match: TPK3 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]) HSP 1 Score: 305.834 bits (782), Expect = 7.641e-102 Identity = 150/295 (50.85%), Postives = 212/295 (71.86%), Query Frame = 1
Query: 211 LSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNI-KGPGDSSNFDDYEEE 1092
LSDF+ LRTLGTGSFGRV L++ + A+K L K +VKLKQVEHT +E+R+L ++ F++R+ F+D+ ++MV++++ GGE+FS LR+ RF P ++FYAA++ LA EYLH D+IYRDLKPEN+L+D G+IK+TDFGFAK V T+TLCGTP+Y+APE++ +K YNK+VDWW+ GVLIYEM AGY PF+ ++ YE I++ +++FP F D +DLL+ L+ DL++R GNL+N D+K H WF W + + +E P+ P I +G GD+S FD Y EE
Sbjct: 85 LSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWFNEVIWEKLLARYIETPYEPPIQQGQGDTSQFDRYPEE 379
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Yeast
Match: YPK1 (S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]) HSP 1 Score: 255.373 bits (651), Expect = 3.134e-79 Identity = 135/310 (43.55%), Postives = 193/310 (62.26%), Query Frame = 1
Query: 187 KPSQNTA-QLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAK---RVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDD--YEEEPL 1098
KPS+N + DF+ L+ +G GSFG+VM V+ K T++ A+K + K +V +V HTL E+ +L + F+V L + F+ LY VL F+NGGE+F HL++ GRF +RFY A+++ A + LH LD++YRDLKPEN+L+D QG+I + DFG K + +T T CGTPEYLAPE++L GY KAVDWW LGVL+YEM G PP++ + ++Y+KI+ + FP F D KDLL LL D T+R G N +I+ H +F W + K P+ P + D+SNFD+ E+P+
Sbjct: 335 KPSRNKPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPDGFDRDAKDLLIGLLSRDPTRRLG--YNGADEIRNHPFFSQLSWKRLLMKGYIPPYKPAVSNSMDTSNFDEEFTREKPI 642
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Yeast
Match: YPK2 (Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]) HSP 1 Score: 253.062 bits (645), Expect = 2.226e-78 Identity = 136/310 (43.87%), Postives = 194/310 (62.58%), Query Frame = 1
Query: 187 KPSQNTA-QLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAK---RVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDD--YEEEPL 1098
KPS+N + DF+ L+ +G GSFG+VM V+ K T++ A+K L K +V +V HTL E+ +L + F+V L + F+ LY+VL F+NGGE+F HL+ GRFS SRFY A+++ A + LH LD+IYRDLKPEN+L+D QG+I + DFG K + +T T CGTPEYLAPEI+L +GY K VDWW LG+L+YEM G PP++ + +Y+KI+ + FP F KDLL LL D ++R G N +I+ H +F + W + K P+ P +K D++NFD +E+P+
Sbjct: 332 KPSKNKPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQPLLFPDGFDPAAKDLLIGLLSRDPSRRLG--VNGTDEIRNHPFFKDISWKKLLLKGYIPPYKPIVKSEIDTANFDQEFTKEKPI 639
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Match: EDO35228 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM62]) HSP 1 Score: 326.25 bits (835), Expect = 2.164e-110 Identity = 169/314 (53.82%), Postives = 221/314 (70.38%), Query Frame = 1
Query: 211 LSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF-SADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIAN--TEKCLKEFADF 1143
L DFE +TLGTG+FGRV+L + + E+ A+KI++ +V++LKQVEH NEK IL +I F+V L + D + LYM+LE+ GGE+F++LR GRF+ F+ ++IV A +YLH ++YRDLKPEN+L+D G++K+TDFGFAK V +TWTLCGTPEYLAPEII SKG+NKAVDWWALG+LIYEM GYPPFF D P IYEKI+SGKV +P H + KDL++ LL D T+R G++KN D+K HKWF DW + +++L+ P P I PGD+ NFDDY EE R A K L+ F DF
Sbjct: 15 LQDFELSKTLGTGTFGRVLLARDRRGGEFYALKIMNISEVIRLKQVEHVQNEKNILMSIEHPFIVNLLWTQHDQTFLYMLLEYACGGELFTYLRTAGRFNNGTGLFFGSEIVSAMDYLHGHSIVYRDLKPENILLDRDGHVKLTDFGFAKEVHDKTWTLCGTPEYLAPEIIQSKGHNKAVDWWALGILIYEMLVGYPPFFDDNPFGIYEKILSGKVEWPKHMDNTSAKDLIKKLLVHDRTRRLGSMKNGSEDVKNHKWFKVIDWNLVLQRKLKPPINPKISHPGDTRNFDDYPEEDWRGAPPLNAKHLEPFKDF 328
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Match: EDO37800 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEW2]) HSP 1 Score: 253.062 bits (645), Expect = 9.030e-81 Identity = 141/340 (41.47%), Postives = 212/340 (62.35%), Query Frame = 1
Query: 100 NNPNSKKNDITDVKAFLEEAKRLFVEKWDKPSQNT--AQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRIL-QAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKR---VKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFD-DYEEEPL 1098
+NP + + + D + ++A VEK D N A+ SDF L+ +G GSFG+V L ++K ++ AIK+L+K + K + +H + E+ +L Q +T FLV L Y F+ LY VL++VNGGE+F HL+R F E +RFYAA+I A YLH L +IYRDLKPEN+L+DS+G+I +TDFG K G T T CGTPEYLAPE++ + Y+K+VDWW LG ++YEM G PPF++ ++Y+ I+ +R ++ S + +L LLQ D TKR G+ + + DI+TH +F + +W + + +E P+ PN+ G D +FD ++ EP+
Sbjct: 35 DNPKNAQANDEDEQPGSDDAD---VEKIDLGESNNPKAKPSDFLFLKVIGKGSFGKVFLSKNKQEDKFYAIKVLNKSAIRKRNEAKHIMAERNVLVQNVTHPFLVGLHYSFQTKDKLYFVLDYVNGGELFFHLQRERYFPESRARFYAAEIASAIGYLHGLQIIYRDLKPENILLDSKGHIVLTDFGLCKEGIDRSGTTSTFCGTPEYLAPEVLRKQDYDKSVDWWCLGAVLYEMMYGLPPFYSRDTAEMYDNILHKPLRLRTNISQSARHILEGLLQKDKTKRLGSGEGDFEDIRTHSFFRSINWQQLVARGIEPPYNPNVSGQLDLKHFDPEFVREPV 371
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Match: EDO38407 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCZ7]) HSP 1 Score: 244.973 bits (624), Expect = 5.292e-75 Identity = 129/293 (44.03%), Postives = 185/293 (63.14%), Query Frame = 1
Query: 208 QLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVK-GR-TWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG--KVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNF 1074
+L D ++TLG G FGRV LVQ K A+K L K +V+ +Q +H ++EK+I+ F+VRL FKD LYM+LE GGE+++ LR G F + +RFY ++ AF+YLH ++YRDLKPENLL+D GY K+ DFGFAK++ GR TWT CGTPEY+APEIIL+KG++ + D+W+LG+L+YE+ G PPF P++ Y I+ G + FP + + L++ L + + +R G K + DI HKWF +W + ++L +P P IK P D+SNF
Sbjct: 348 RLEDLTVVKTLGIGGFGRVELVQVAGDKRTFALKTLKKHHIVETRQQDHIMSEKKIMMESNSPFIVRLHKTFKDKKYLYMLLEVCLGGELWTILRDRGSFDDSTTRFYVGCVIEAFQYLHSKGIVYRDLKPENLLLDGHGYCKLVDFGFAKKIGFGRKTWTFCGTPEYVAPEIILNKGHDLSADYWSLGILMYELLTGSPPFSGTDPMKTYNIILKGIDMIDFPRKITRNAHALIKKLCRDNPVERLGYQKGGLKDIMKHKWFDGFNWDGLRSRKLNSPIAPKIKSPVDASNF 640
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Match: EDO41166 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S521]) HSP 1 Score: 233.032 bits (593), Expect = 6.347e-73 Identity = 118/303 (38.94%), Postives = 172/303 (56.77%), Query Frame = 1
Query: 190 PSQNTAQLSDFERLRTLGTGSFGRVMLVQ----HKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRV---KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFD 1077
P FE L+ LG G +G+V LV+ H K + + + K HT E+ IL+ + F+V L Y F+ LY++LE+++GGE+F L R G F E + FY ++I +A E+LH ++YRDLKPEN+L+D+ G++K+TDFG K T T CGT EY+APEI+ G+ KAVDWW+LG L+Y+M G PPF AD + +KI+ GK+ P + + + KD +R LL+ R G + + IK H +F + W + K++E PF P+I G D S FD
Sbjct: 55 PKDEKVGPESFELLKVLGKGGYGKVFLVKKNHGHSKEKIFAMKVLKKAAIIRSQKDTAHTKAERNILECVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFLEDTACFYLSEISMALEHLHKQGIVYRDLKPENILLDANGHVKLTDFGLCKESIFENSLTHTFCGTIEYMAPEILTRSGHGKAVDWWSLGALMYDMLTGTPPFCADNRKKTIDKILKGKLIIPPYLTPEAKDFIRKLLKRHPQARLGGMAGDANPIKAHSFFRHICWEDLLAKKVEPPFRPSISGEEDVSQFD 357
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Match: EDO38399 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCY8]) HSP 1 Score: 220.705 bits (561), Expect = 7.488e-66 Identity = 131/307 (42.67%), Postives = 190/307 (61.89%), Query Frame = 1
Query: 91 VIGNNPNSKKNDITDVKAFLEEAKRLF--VEKWDKPSQNTAQLS--DFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRV-KGR-TWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG--KVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFL 987
VIGN ++ D D K AKR E+ K S+ A L+ D E + TLGTG FGRV LV + A+K L K+ ++ +Q EH +EKRIL F+ ++ FKD +YM+LE GGE+++ LR G F + +RF A +V FEYLH ++YRDLKPENLL+D++GY+K+ DFGFAK++ GR TWT CGTPEY+APEIIL+KG++ + D+W+LG+LI+E+ G PPF + P++ Y I+ G V FP + ++L++ L + + +R G K+ + DIK HK+ +
Sbjct: 287 VIGNMDELREKDYGDEK---RGAKRTLDVPEEERKVSKEFADLTLEDLEVVATLGTGGFGRVELVTY-------ALKCLKKKHILDTRQQEHVYSEKRILMETNSPFICKIYRTFKDRKYVYMLLEACLGGELWTILRDRGTFEDATARFCIACVVEGFEYLHSKGIVYRDLKPENLLLDAKGYVKLVDFGFAKKIGSGRKTWTFCGTPEYVAPEIILNKGHDLSSDYWSLGILIFELLTGSPPFSSSDPMKTYNIILRGLDMVEFPKRIGRNPQNLIKRLCKDNPVERLGYQKDGLSDIKKHKYVV 583
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Medaka
Match: ENSORLT00000040218.1 (cAMP-dependent protein kinase catalytic subunit alpha [Source:NCBI gene;Acc:101160964]) HSP 1 Score: 564.688 bits (1454), Expect = 0.000e+0 Identity = 277/351 (78.92%), Postives = 316/351 (90.03%), Query Frame = 1
Query: 94 IGNNPNSKK-NDITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+GN P ++K N++ VK FL +AK F++KW+ PSQNTA L FERL+TLGTGSFGRVMLV+H+ T ++ A+KIL+KQKVVKLKQ+EHTLNEKRILQA++F FLVRL++ FKDN+NLYMV+E+V GGEMFSHLR+IGRFSEPH+RFYA QIVL FEYLH LDLIYRDLKPENLLID QGYI+VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVL+YEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS+DLKDLLRNLLQVDLTKRYGNLKN V DIK HKWF DWI IF+K++EAPF+P KGPGD+SNFDDYEEE +R++ +EKC KEFA+F
Sbjct: 1 MGNAPTARKGNEMESVKEFLAKAKEDFLKKWENPSQNTANLEQFERLKTLGTGSFGRVMLVKHRETGQHYAMKILNKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEFSFKDNTNLYMVMEYVPGGEMFSHLRKIGRFSEPHARFYATQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKGHKWFAATDWIAIFQKKVEAPFVPKFKGPGDTSNFDDYEEEEIRVSFSEKCAKEFAEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Medaka
Match: prkacaa (cAMP-dependent protein kinase catalytic subunit alpha [Source:NCBI gene;Acc:101163742]) HSP 1 Score: 560.836 bits (1444), Expect = 0.000e+0 Identity = 277/351 (78.92%), Postives = 315/351 (89.74%), Query Frame = 1
Query: 94 IGNNPNSKK-NDITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+GN P +KK N++ VK FL +AK F++KW+ P+Q TA L FERL+TLGTGSFGRVMLV+HK T ++ A+KILDKQKVVKLKQ+EHTLNEKRILQA++F FLV+L++ FKD SNLYMV+E+V GGEMFSHLRRIGRFSEPH+RFYAAQIVL FEYLH LDLIYRDLKPENLLID QGYI+VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS+DLKDLLRNLLQVDLTKR+GNL+N V DIK HKWF DWI I+++++EAPFIP KGPGD+SNFDDYEEE +R++ +EKC KEFA+F
Sbjct: 1 MGNTPTAKKGNEVESVKEFLAKAKEDFLKKWENPAQQTAALDHFERLKTLGTGSFGRVMLVKHKETGQHFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVQLEHSFKDTSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLRNGVNDIKGHKWFATTDWIAIYQRKVEAPFIPKCKGPGDTSNFDDYEEEEIRVSFSEKCAKEFAEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Medaka
Match: ENSORLT00000033457.1 (cAMP-dependent protein kinase catalytic subunit beta [Source:NCBI gene;Acc:101170876]) HSP 1 Score: 558.91 bits (1439), Expect = 0.000e+0 Identity = 278/351 (79.20%), Postives = 314/351 (89.46%), Query Frame = 1
Query: 94 IGNNPNSKK-NDITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+GN +KK N++ VK FL +AK F+ KW+ P Q+T L DF+R++TLGTGSFGRVMLV+HK +++Y A+KILDKQKVVKLKQ+EHTLNEKRILQA++F FLVRL+Y FKDNSNLYMV+E+V GGEMFSHLRRIGRFSEPH+RFYAAQIVL FEYLH LDLIYRDLKPENLLID GYI+VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS+DLKDLLRNLLQVDLTKRYGNLKN V DIK HKWF DWI I+++++EAPFIP +GPGD+SNFDDYEEE +R++ TEKC KEFA+F
Sbjct: 1 MGNAATAKKGNELESVKEFLAKAKEDFLRKWECPPQSTTCLEDFDRIKTLGTGSFGRVMLVKHKSSEQYFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHHGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKGHKWFATTDWIAIYERKVEAPFIPKCRGPGDTSNFDDYEEEEIRVSLTEKCAKEFAEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Medaka
Match: ENSORLT00000018528.2 (cAMP-dependent protein kinase catalytic subunit alpha [Source:NCBI gene;Acc:101160964]) HSP 1 Score: 556.984 bits (1434), Expect = 0.000e+0 Identity = 277/359 (77.16%), Postives = 316/359 (88.02%), Query Frame = 1
Query: 94 IGNNPNSKK-NDITDVKAFLEEAKRLFVEKWDKPSQ--------NTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+GN P ++K N++ VK FL +AK F++KW+ PSQ NTA L FERL+TLGTGSFGRVMLV+H+ T ++ A+KIL+KQKVVKLKQ+EHTLNEKRILQA++F FLVRL++ FKDN+NLYMV+E+V GGEMFSHLR+IGRFSEPH+RFYA QIVL FEYLH LDLIYRDLKPENLLID QGYI+VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVL+YEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS+DLKDLLRNLLQVDLTKRYGNLKN V DIK HKWF DWI IF+K++EAPF+P KGPGD+SNFDDYEEE +R++ +EKC KEFA+F
Sbjct: 1 MGNAPTARKGNEMESVKEFLAKAKEDFLKKWENPSQGQDFFQFANTANLEQFERLKTLGTGSFGRVMLVKHRETGQHYAMKILNKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEFSFKDNTNLYMVMEYVPGGEMFSHLRKIGRFSEPHARFYATQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKGHKWFAATDWIAIFQKKVEAPFVPKFKGPGDTSNFDDYEEEEIRVSFSEKCAKEFAEF 359
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Medaka
Match: ENSORLT00000035979.1 (cAMP-dependent protein kinase catalytic subunit beta [Source:NCBI gene;Acc:101170876]) HSP 1 Score: 554.673 bits (1428), Expect = 0.000e+0 Identity = 279/354 (78.81%), Postives = 315/354 (88.98%), Query Frame = 1
Query: 94 IGNNPNSKK-NDI---TDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+GN +KK N++ T VK FL +AK F+ KW+ P Q+T L DF+R++TLGTGSFGRVMLV+HK +++Y A+KILDKQKVVKLKQ+EHTLNEKRILQA++F FLVRL+Y FKDNSNLYMV+E+V GGEMFSHLRRIGRFSEPH+RFYAAQIVL FEYLH LDLIYRDLKPENLLID GYI+VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS+DLKDLLRNLLQVDLTKRYGNLKN V DIK HKWF DWI I+++++EAPFIP +GPGD+SNFDDYEEE +R++ TEKC KEFA+F
Sbjct: 1 MGNAATAKKGNELESDTFVKEFLAKAKEDFLRKWECPPQSTTCLEDFDRIKTLGTGSFGRVMLVKHKSSEQYFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHHGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKGHKWFATTDWIAIYERKVEAPFIPKCRGPGDTSNFDDYEEEEIRVSLTEKCAKEFAEF 354
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Planmine SMEST
Match: SMESG000038292.1 (SMESG000038292.1) HSP 1 Score: 668.307 bits (1723), Expect = 0.000e+0 Identity = 336/336 (100.00%), Postives = 336/336 (100.00%), Query Frame = 1
Query: 136 VKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
VKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAIKILDKQKVVKLKQVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF
Sbjct: 172 VKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAIKILDKQKVVKLKQVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 507
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Planmine SMEST
Match: SMESG000038292.1 (SMESG000038292.1) HSP 1 Score: 667.537 bits (1721), Expect = 0.000e+0 Identity = 336/336 (100.00%), Postives = 336/336 (100.00%), Query Frame = 1
Query: 136 VKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
VKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAIKILDKQKVVKLKQVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF
Sbjct: 295 VKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAIKILDKQKVVKLKQVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 630
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Planmine SMEST
Match: SMESG000038292.1 (SMESG000038292.1) HSP 1 Score: 667.152 bits (1720), Expect = 0.000e+0 Identity = 335/336 (99.70%), Postives = 336/336 (100.00%), Query Frame = 1
Query: 136 VKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+KAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAIKILDKQKVVKLKQVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF
Sbjct: 247 MKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAIKILDKQKVVKLKQVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 582
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Planmine SMEST
Match: SMESG000016651.1 (SMESG000016651.1) HSP 1 Score: 520.39 bits (1339), Expect = 0.000e+0 Identity = 253/352 (71.88%), Postives = 305/352 (86.65%), Query Frame = 1
Query: 94 IGNNPNSKKN--DITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
+GN P K++ D + VK FLEEAK+ F +K+D P Q T +L +FE L+TLGTGSFGRV+L HK +K+Y A+K+LDK K+VKLKQVEHTLNEKRILQAI F FL++LDY FKDNSNLYMVLEFVNGGEMFSHLRR+G+FSE H++FYA+Q+VLAFEYLH+LDLIYRDLKPEN+LID++GY+K+TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+R+GN++N DIK H WF + DW + FKKEL APFIP +GPGD+SNFD+YEEE L+I+ T KC EF +F
Sbjct: 1 MGNTPTVKRDEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAVKVLDKLKIVKLKQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 352
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Planmine SMEST
Match: SMESG000000892.1 (SMESG000000892.1) HSP 1 Score: 473.781 bits (1218), Expect = 7.919e-168 Identity = 235/345 (68.12%), Postives = 281/345 (81.45%), Query Frame = 1
Query: 112 SKKNDITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAXXXXXXXXXXXXXXVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFL-NCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 1143
SKK + +V+ FLE A++ F +KWD P N A L++F R++TLGTG+FG V+LV T Y A+K+L+KQK+VK+KQVEHTLNEKRILQA+ F FLV L Y FKDNS LY+VLE+V GGEMFSHLR+ GR+SE + FYA+Q+V+ FEYLHYLD++YRDLKPEN+LI+ GYIK+TDFGFAKR+KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALG+LIYEM GYPPF ADQPI IYEKIV GK +FP++ S D KDL+R LLQ DLTKRYGNLKN V DIK HKWF N DWI I+K+++ PF P +K GD+S FDDY+EEPL+I+ EKC KEF DF
Sbjct: 6 SKKENNCEVEEFLENARQEFFDKWDLPVHNNATLAEFTRVKTLGTGTFGTVILVYKPQTDTYYAMKVLNKQKIVKMKQVEHTLNEKRILQAVNFPFLVNLHYSFKDNSYLYLVLEYVVGGEMFSHLRKSGRYSECQANFYASQVVMTFEYLHYLDIVYRDLKPENILINKNGYIKITDFGFAKRIKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGILIYEMIVGYPPFIADQPIHIYEKIVIGKFKFPNYVSPDAKDLIRCLLQSDLTKRYGNLKNGVADIKNHKWFYGNSDWINIYKEKILPPFKPELKSIGDTSYFDDYDEEPLKISKREKCAKEFLDF 350 The following BLAST results are available for this feature:
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30021250 ID=SMED30021250|Name=cAMP-dependent protein kinase catalytic subunit|organism=Schmidtea mediterranea sexual|type=transcript|length=1170bpback to top protein sequence of SMED30021250-orf-1 >SMED30021250-orf-1 ID=SMED30021250-orf-1|Name=SMED30021250-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=359bp MIKKLNKVIGNNPNSKKNDITDVKAFLEEAKRLFVEKWDKPSQNTAQLSDback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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