ANK_REP_REGION domain-containing protein

Overview
NameANK_REP_REGION domain-containing protein
Smed IDSMED30021240
Length (bp)1665
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of ANK_REP_REGION domain-containing protein (SMED30021240) t-SNE clustered cells

Violin plots show distribution of expression levels for ANK_REP_REGION domain-containing protein (SMED30021240) in cells (dots) of each of the 12 neoblast clusters.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30021240

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30021240h1SMcG0014822 SmedASXL_014274SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30021240h1SMcG0014822 SmedASXL_014274SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X1 cellSMED30021240h1SMcG0014822 SmedASXL_072985SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
tail regionSMED30021240h1SMcG0014822 dd_Smed_v6_15557_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
neoblastSMED30021240h1SMcG0014822 SMED_14799_V2_1GPL14150PMID:22385657
Wagner et al., 2012		whole organism asexual adult cDNA to DNA expression microarray evidence
neoblastSMED30021240h1SMcG0014822 SMED_14799_V2_1GPL14150_gene_modelsPMID:22385657
Wagner et al., 2012		whole organism asexual adult cDNA to DNA expression microarray evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Human
Match: TONSL (tonsoku like, DNA repair protein [Source:HGNC Symbol;Acc:HGNC:7801])

HSP 1 Score: 60.4622 bits (145), Expect = 7.071e-9
Identity = 46/170 (27.06%), Postives = 84/170 (49.41%), Query Frame = 1 
Query:   28 KKRKAITNKSKIDACIEIAILHTENCDIQQAISEYKEVLELADECDDLNMKGKAYRYIGESLLDLHQPMEALEYIKEYLKVAQKSKDIFEIQRAYVTIGRCFLDFSEIVKNPTVKQTVAIKSENAFVKSLQLCQQISENEENLISNYKSITELTNELAEMRAVSLFNLGL 537
            K ++A   + +   C ++  L   +    +A+ ++ + L+L +  DD      A+R IGE L ++     AL++  +YL++A   ++  E+QRA+ TIGR  LD  +  ++    +   ++++ AF KSL +   + E  E  ++          EL EMR     NLGL
Sbjct:   16 KAQRAGQRREEAALCHQLGELLAGHGRYAEALEQHWQELQLRERADDPLGCAVAHRKIGERLAEMEDYPAALQHQHQYLELAHSLRNHTELQRAWATIGRTHLDIYDHCQS----RDALLQAQAAFEKSLAI---VDEELEGTLAQ--------GELNEMRTRLYLNLGL 170
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Zebrafish
Match: tonsl (tonsoku-like, DNA repair protein [Source:NCBI gene;Acc:492655])

HSP 1 Score: 58.5362 bits (140), Expect = 1.970e-8
Identity = 62/218 (28.44%), Postives = 101/218 (46.33%), Query Frame = 1 
Query:   10 LKDLLLKKRKAITN---KSKIDACIEIAILHTENCDIQQAISEYKEVLELADECDDLNMKGKAYRYIGESLLDLHQPMEALEYIKEYLKVAQKSKDIFEIQRAYVTIGRCFLDFSEIVKNPTVKQTVAIKSENAFVKSLQLCQQISENEENLISNYKSITELTNELAEMRAVSLFNLGLANRVKSDEKSFRTAERYFIQCSNISVKHKLNEMLLRSTF 654
            +K L   K KA ++   K +   C ++  ++ +  D Q AI E+++ L L++   D+     A R IGE   +L     AL++ + +L +A+   D  E QRA  TIGR +L   +  ++    +     +E+AF KSL +   + E  E  +S          E++EM+A  L NLG    V    K  +       Q   I+ K+ L E L R+ F
Sbjct:    7 IKQLQKAKSKAQSSNNLKEEASLCNQLGEVYAKTGDYQAAIEEHRQELALSEILHDVIGSAVANRKIGECYAELGNIEAALKHQRLHLNLARSVHDAAEEQRALATIGRTYLFLFDSDQSANSLK----HAEDAFKKSLAI---VDERLEGTVS--------PREISEMKARLLLNLGC---VYDGMKEPQRCSDLIRQSIYIAEKNNLLEDLYRANF 206
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Zebrafish
Match: tonsl (tonsoku-like, DNA repair protein [Source:NCBI gene;Acc:492655])

HSP 1 Score: 58.5362 bits (140), Expect = 2.067e-8
Identity = 62/218 (28.44%), Postives = 101/218 (46.33%), Query Frame = 1 
Query:   10 LKDLLLKKRKAITN---KSKIDACIEIAILHTENCDIQQAISEYKEVLELADECDDLNMKGKAYRYIGESLLDLHQPMEALEYIKEYLKVAQKSKDIFEIQRAYVTIGRCFLDFSEIVKNPTVKQTVAIKSENAFVKSLQLCQQISENEENLISNYKSITELTNELAEMRAVSLFNLGLANRVKSDEKSFRTAERYFIQCSNISVKHKLNEMLLRSTF 654
            +K L   K KA ++   K +   C ++  ++ +  D Q AI E+++ L L++   D+     A R IGE   +L     AL++ + +L +A+   D  E QRA  TIGR +L   +  ++    +     +E+AF KSL +   + E  E  +S          E++EM+A  L NLG    V    K  +       Q   I+ K+ L E L R+ F
Sbjct:    7 IKQLQKAKSKAQSSNNLKEEASLCNQLGEVYAKTGDYQAAIEEHRQELALSEILHDVIGSAVANRKIGECYAELGNIEAALKHQRLHLNLARSVHDAAEEQRALATIGRTYLFLFDSDQSANSLK----HAEDAFKKSLAI---VDERLEGTVS--------PREISEMKARLLLNLGC---VYDGMKEPQRCSDLIRQSIYIAEKNNLLEDLYRANF 206
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Zebrafish
Match: tonsl (tonsoku-like, DNA repair protein [Source:NCBI gene;Acc:492655])

HSP 1 Score: 58.5362 bits (140), Expect = 2.067e-8
Identity = 62/218 (28.44%), Postives = 101/218 (46.33%), Query Frame = 1 
Query:   10 LKDLLLKKRKAITN---KSKIDACIEIAILHTENCDIQQAISEYKEVLELADECDDLNMKGKAYRYIGESLLDLHQPMEALEYIKEYLKVAQKSKDIFEIQRAYVTIGRCFLDFSEIVKNPTVKQTVAIKSENAFVKSLQLCQQISENEENLISNYKSITELTNELAEMRAVSLFNLGLANRVKSDEKSFRTAERYFIQCSNISVKHKLNEMLLRSTF 654
            +K L   K KA ++   K +   C ++  ++ +  D Q AI E+++ L L++   D+     A R IGE   +L     AL++ + +L +A+   D  E QRA  TIGR +L   +  ++    +     +E+AF KSL +   + E  E  +S          E++EM+A  L NLG    V    K  +       Q   I+ K+ L E L R+ F
Sbjct:    7 IKQLQKAKSKAQSSNNLKEEASLCNQLGEVYAKTGDYQAAIEEHRQELALSEILHDVIGSAVANRKIGECYAELGNIEAALKHQRLHLNLARSVHDAAEEQRALATIGRTYLFLFDSDQSANSLK----HAEDAFKKSLAI---VDERLEGTVS--------PREISEMKARLLLNLGC---VYDGMKEPQRCSDLIRQSIYIAEKNNLLEDLYRANF 206
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Zebrafish
Match: tonsl (tonsoku-like, DNA repair protein [Source:NCBI gene;Acc:492655])

HSP 1 Score: 54.299 bits (129), Expect = 3.794e-7
Identity = 55/183 (30.05%), Postives = 85/183 (46.45%), Query Frame = 1 
Query:  106 DIQQAISEYKEVLELADECDDLNMKGKAYRYIGESLLDLHQPMEALEYIKEYLKVAQKSKDIFEIQRAYVTIGRCFLDFSEIVKNPTVKQTVAIKSENAFVKSLQLCQQISENEENLISNYKSITELTNELAEMRAVSLFNLGLANRVKSDEKSFRTAERYFIQCSNISVKHKLNEMLLRSTF 654
            D Q AI E+++ L L++   D+     A R IGE   +L     AL++ + +L +A+   D  E QRA  TIGR +L   +  ++    +     +E+AF KSL +   + E  E  +S          E++EM+A  L NLG    V    K  +       Q   I+ K+ L E L R+ F
Sbjct:   10 DYQAAIEEHRQELALSEILHDVIGSAVANRKIGECYAELGNIEAALKHQRLHLNLARSVHDAAEEQRALATIGRTYLFLFDSDQSANSLK----HAEDAFKKSLAI---VDERLEGTVS--------PREISEMKARLLLNLGC---VYDGMKEPQRCSDLIRQSIYIAEKNNLLEDLYRANF 174
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Mouse
Match: Tonsl (tonsoku-like, DNA repair protein [Source:MGI Symbol;Acc:MGI:1919999])

HSP 1 Score: 55.0694 bits (131), Expect = 1.535e-7
Identity = 44/156 (28.21%), Postives = 76/156 (48.72%), Query Frame = 1 
Query:   70 CIEIAILHTENCDIQQAISEYKEVLELADECDDLNMKGKAYRYIGESLLDLHQPMEALEYIKEYLKVAQKSKDIFEIQRAYVTIGRCFLDFSEIVKNPTVKQTVAIKSENAFVKSLQLCQQISENEENLISNYKSITELTNELAEMRAVSLFNLGL 537
            C ++  L   +   + A+ E+++ L L +   D      A+R IGE L ++     AL++   YL +A    +  E+QRA+ TIGR  LD  +  ++    +   ++++ AF KSL +   + E  E +++          EL+EMR     NLGL
Sbjct:   30 CHQLGELLASHGRFKDALEEHQQELHLLESVQDTLGCAVAHRKIGERLAEMENYSAALKHQHLYLDLAGSLSNHTELQRAWATIGRTHLDIYDHCQS----RDSLLQAQAAFEKSLAI---VDEKLEGMLTQ--------RELSEMRTRLYLNLGL 170
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Mouse
Match: Tonsl (tonsoku-like, DNA repair protein [Source:MGI Symbol;Acc:MGI:1919999])

HSP 1 Score: 54.6842 bits (130), Expect = 2.821e-7
Identity = 44/156 (28.21%), Postives = 76/156 (48.72%), Query Frame = 1 
Query:   70 CIEIAILHTENCDIQQAISEYKEVLELADECDDLNMKGKAYRYIGESLLDLHQPMEALEYIKEYLKVAQKSKDIFEIQRAYVTIGRCFLDFSEIVKNPTVKQTVAIKSENAFVKSLQLCQQISENEENLISNYKSITELTNELAEMRAVSLFNLGL 537
            C ++  L   +   + A+ E+++ L L +   D      A+R IGE L ++     AL++   YL +A    +  E+QRA+ TIGR  LD  +  ++    +   ++++ AF KSL +   + E  E +++          EL+EMR     NLGL
Sbjct:   30 CHQLGELLASHGRFKDALEEHQQELHLLESVQDTLGCAVAHRKIGERLAEMENYSAALKHQHLYLDLAGSLSNHTELQRAWATIGRTHLDIYDHCQS----RDSLLQAQAAFEKSLAI---VDEKLEGMLTQ--------RELSEMRTRLYLNLGL 170
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. UniProt/SwissProt
Match: sp|Q96HA7|TONSL_HUMAN (Tonsoku-like protein OS=Homo sapiens OX=9606 GN=TONSL PE=1 SV=2)

HSP 1 Score: 60.4622 bits (145), Expect = 3.396e-8
Identity = 46/170 (27.06%), Postives = 84/170 (49.41%), Query Frame = 1 
Query:   28 KKRKAITNKSKIDACIEIAILHTENCDIQQAISEYKEVLELADECDDLNMKGKAYRYIGESLLDLHQPMEALEYIKEYLKVAQKSKDIFEIQRAYVTIGRCFLDFSEIVKNPTVKQTVAIKSENAFVKSLQLCQQISENEENLISNYKSITELTNELAEMRAVSLFNLGL 537
            K ++A   + +   C ++  L   +    +A+ ++ + L+L +  DD      A+R IGE L ++     AL++  +YL++A   ++  E+QRA+ TIGR  LD  +  ++    +   ++++ AF KSL +   + E  E  ++          EL EMR     NLGL
Sbjct:   16 KAQRAGQRREEAALCHQLGELLAGHGRYAEALEQHWQELQLRERADDPLGCAVAHRKIGERLAEMEDYPAALQHQHQYLELAHSLRNHTELQRAWATIGRTHLDIYDHCQS----RDALLQAQAAFEKSLAI---VDEELEGTLAQ--------GELNEMRTRLYLNLGL 170
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. UniProt/SwissProt
Match: sp|D4A615|TONSL_RAT (Tonsoku-like protein OS=Rattus norvegicus OX=10116 GN=Tonsl PE=3 SV=1)

HSP 1 Score: 58.9214 bits (141), Expect = 1.117e-7
Identity = 55/197 (27.92%), Postives = 95/197 (48.22%), Query Frame = 1 
Query:   70 CIEIAILHTENCDIQQAISEYKEVLELADECDDLNMKGKAYRYIGESLLDLHQPMEALEYIKEYLKVAQKSKDIFEIQRAYVTIGRCFLDFSEIVKNPTVKQTVAIKSENAFVKSLQLCQQISENEENLISNYKSITELTNELAEMRAVSLFNLGLANRVKSDEKSFRTAE--RYFIQCSNISVKHKLNEMLLRSTF 654
            C ++  L   +   Q+A+ E+++ L L +   D      A+R IGE L ++     AL++   YL +A    +  E+QRA+ TIGR  LD    V +    +   ++++ AF KSL +   + E  E +++          EL+EMR     NLGL     + E   +TA+   YF +   ++ ++ L E L R+ +
Sbjct:   30 CHQLGELLASHGRFQEALEEHQQELHLLESVQDTLGCAVAHRKIGERLAEMENYSAALKHQHLYLDLAGSLSNHTELQRAWATIGRTHLD----VYDHCQSRDSLLQAQAAFEKSLAI---VDEKLEGMLTQ--------RELSEMRTRLYLNLGL-----TCESLQQTAQCNNYFKKSIFLAEQNHLYEDLFRARY 206
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. UniProt/SwissProt
Match: sp|A9JR78|TONSL_DANRE (Tonsoku-like protein OS=Danio rerio OX=7955 GN=tonsl PE=2 SV=1)

HSP 1 Score: 57.3806 bits (137), Expect = 3.152e-7
Identity = 61/218 (27.98%), Postives = 101/218 (46.33%), Query Frame = 1 
Query:   10 LKDLLLKKRKAITN---KSKIDACIEIAILHTENCDIQQAISEYKEVLELADECDDLNMKGKAYRYIGESLLDLHQPMEALEYIKEYLKVAQKSKDIFEIQRAYVTIGRCFLDFSEIVKNPTVKQTVAIKSENAFVKSLQLCQQISENEENLISNYKSITELTNELAEMRAVSLFNLGLANRVKSDEKSFRTAERYFIQCSNISVKHKLNEMLLRSTF 654
            +K L   K KA ++   K +   C ++  ++ +  D Q AI E+++ L L++   D+     A R IGE   +L     AL++ + +L +A+   D  E QRA  TIGR +L   +  ++    +     +E+AF +SL +   + E  E  +S          E++EM+A  L NLG    V    K  +       Q   I+ K+ L E L R+ F
Sbjct:    7 IKQLQKAKSKAQSSNNLKEEASLCNQLGEVYAKTGDYQAAIEEHRQELALSEILHDVIGSAVANRKIGECYAELGNIEAALKHQRLHLNLARSVHDAAEEQRALATIGRTYLFLFDSDQSANSLK----HAEDAFKRSLAI---VDERLEGTVS--------PREISEMKARLLLNLGC---VYDGMKEPQRCSDLIRQSIYIAEKNNLLEDLYRANF 206
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. UniProt/SwissProt
Match: sp|Q0P5G1|TONSL_BOVIN (Tonsoku-like protein OS=Bos taurus OX=9913 GN=TONSL PE=2 SV=1)

HSP 1 Score: 56.225 bits (134), Expect = 6.947e-7
Identity = 47/170 (27.65%), Postives = 81/170 (47.65%), Query Frame = 1 
Query:   28 KKRKAITNKSKIDACIEIAILHTENCDIQQAISEYKEVLELADECDDLNMKGKAYRYIGESLLDLHQPMEALEYIKEYLKVAQKSKDIFEIQRAYVTIGRCFLDFSEIVKNPTVKQTVAIKSENAFVKSLQLCQQISENEENLISNYKSITELTNELAEMRAVSLFNLGL 537
            K +++   + +   C ++  L   +    +A+ E+++ L+L +  DD      A+R IGE L ++     AL++   YL++A    +  E QRA+ TIGR  LD    + +    Q    ++++AF KSL +       +E L  +         EL+EMR     NLGL
Sbjct:   16 KAQRSGQLREEASVCHQLGELLASHGCYAEALREHQQELQLLETTDDPLGCAVAHRKIGERLAEMEDYSAALQHQHRYLELACALSNHVEQQRAWATIGRTHLD----IYDHHQSQDALQQAQDAFEKSLAIL------DEKLQGSLPK-----RELSEMRTRIYLNLGL 170
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6NZL6|TONSL_MOUSE (Tonsoku-like protein OS=Mus musculus OX=10090 GN=Tonsl PE=1 SV=2)

HSP 1 Score: 54.6842 bits (130), Expect = 2.077e-6
Identity = 44/156 (28.21%), Postives = 76/156 (48.72%), Query Frame = 1 
Query:   70 CIEIAILHTENCDIQQAISEYKEVLELADECDDLNMKGKAYRYIGESLLDLHQPMEALEYIKEYLKVAQKSKDIFEIQRAYVTIGRCFLDFSEIVKNPTVKQTVAIKSENAFVKSLQLCQQISENEENLISNYKSITELTNELAEMRAVSLFNLGL 537
            C ++  L   +   + A+ E+++ L L +   D      A+R IGE L ++     AL++   YL +A    +  E+QRA+ TIGR  LD  +  ++    +   ++++ AF KSL +   + E  E +++          EL+EMR     NLGL
Sbjct:   30 CHQLGELLASHGRFKDALEEHQQELHLLESVQDTLGCAVAHRKIGERLAEMENYSAALKHQHLYLDLAGSLSNHTELQRAWATIGRTHLDIYDHCQS----RDSLLQAQAAFEKSLAI---VDEKLEGMLTQ--------RELSEMRTRLYLNLGL 170
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. TrEMBL
Match: A0A504YA07 (Nalp (Nacht leucine rich repeat and pyrin domain containing) OS=Fasciola gigantica OX=46835 GN=FGIG_12160 PE=4 SV=1)

HSP 1 Score: 123.25 bits (308), Expect = 3.917e-27
Identity = 109/383 (28.46%), Postives = 191/383 (49.87%), Query Frame = 1 
Query:   10 LKDLLLKKRKAITNKSKIDACIEIAILHTENCDIQQAISEYKEVLELADECDDLNMKGKAYRYIGESLLDLHQPMEALEYIKEYLKVAQKSKDIFEIQRAYVTIGRCFLDFSEIVKNPTVKQTVAIKSENAFVKSLQLCQQISENEENLISNYKSITELTNE-----LAEMRAVSLFNLGLANRVKSDEKSFRTAERYFIQCSNISVKHKLNEMLLRSTFQQFDLNYSQSLNQ----------WTIANSGKSRLIVEESLKVLRKNFGLMTGIPFTSV---MKKIAKEIHELEAQCLIVAERFHKAAKKFRNLMRRSHNCRSNYRMKMLSAIKLSE---KLPRATNNEDIIL---------IGQIYDELGIQLVAGKYYEVAL 1068
            LK LL ++ +A + K + D  +EIA+LHTE+ +   A+ EYK++LEL     D      ++R+I +  ++L    +A+ +  +YLK+A +  +  E QRA+VT+GRCFL+ +E++K+    +                 + +    + L+S+ K ITE T E     L EMRAVSL NLG   R + ++ S   A   F QC +++ K++L ++L R+ +Q  DL+ +    Q           ++ NS   R +    L +L+    L++ +  T++    K++ K + E  AQ  +   +F KAAK +R L   + N     R  +   ++LS     +P + +++   L         +G IY EL +   A ++Y+  L
Sbjct:    3 LKKLLEQRTRAKSAKEQADITLEIAVLHTESGEHVHALREYKKLLELWQSKGDKFQCAISHRFIADCCIELDDYDQAISHTNQYLKLATELGNKLEQQRAFVTLGRCFLNRAELMKDGDSTK-----------------RNLKSAAQALLSSIKMITEFTGELDSKQLGEMRAVSLLNLGQVFRAQREQTS---ALERFTQCISLARKYQLQKLLFRACYQIADLSINMPPTQKYEPLDRASLISLMNSTSLRNV----LTILQ--MALVSPMAKTNLDHETKELLKSLRESMAQVYLSVGQFRKAAKVYRLLKLHNPNSSDYCRRLIRKCMRLSNLMYTIPESVSSDLDSLRATSKAHEKMGDIYSELEMHGPALRHYQFML 359
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. TrEMBL
Match: A0A4E0RVD8 (ANK_REP_REGION domain-containing protein OS=Fasciola hepatica OX=6192 GN=D915_002811 PE=4 SV=1)

HSP 1 Score: 124.405 bits (311), Expect = 8.291e-26
Identity = 104/377 (27.59%), Postives = 186/377 (49.34%), Query Frame = 1 
Query:   28 KKRKAITNKSKIDACIEIAILHTENCDIQQAISEYKEVLELADECDDLNMKGKAYRYIGESLLDLHQPMEALEYIKEYLKVAQKSKDIFEIQRAYVTIGRCFLDFSEIVKNPTVKQTVAIKSENAFVKSLQLCQQISENEENLISNYKSITELTNE-----LAEMRAVSLFNLGLANRVKSDEKSFRTAERYFIQCSNISVKHKLNEMLLRSTFQQFDLNYSQSLNQ----------WTIANSGKSRLIVEESLKVLRKNFGLMTGIPFTSV---MKKIAKEIHELEAQCLIVAERFHKAAKKFRNLMRRSHNCRSNYRMKMLSAIKLSE---KLPRATNNEDIIL---------IGQIYDELGIQLVAGKYYEVAL 1068
            ++ +A + K + D  +EIA+LHTE+ +   A+ EYK++LEL     D      ++R+I +  ++L    +A+ +  +YLK+A +  +  E QRA+VT+GRCFL+ +E++K+    +                 + +    + L+S+ K ITE T E     L EMRAVSL NLG   R + +      A   F QC +++ K++L ++L R+ +Q  DL+ +    Q           ++ NS   R +    L +L+    L++ +  T++    K++ K + E  AQ  +   +F KAAK +R L   + N     R  +   ++LS     +P + +++   L         +G IY EL +   A ++Y++ L
Sbjct:    6 QRTRAKSAKEQADITLEIAVLHTESGEHVHALREYKKLLELWQSKGDKFQCAISHRFIADCCIELDDYDQAISHTNQYLKLATELGNKLEQQRAFVTLGRCFLNRAELMKDGDSTK-----------------RNLKSAAQALLSSIKMITEFTGELDSKQLGEMRAVSLLNLGQVFRAQRERTG---ALERFTQCISLARKYQLQKLLFRACYQIADLSINMPPTQKYEPLDRASLISLMNSTSLRNV----LTILQ--MALVSPMAKTNLDHETKELLKSLRESMAQVYLSVGQFRKAAKVYRLLKLHNPNSSDYCRRLIRKCMRLSNLMYAIPESVSSDLDSLRATSKAHEKMGDIYSELEMHGPALRHYQLML 356
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. TrEMBL
Match: A0A183A0T0 (Uncharacterized protein OS=Echinostoma caproni OX=27848 GN=ECPE_LOCUS565 PE=4 SV=1)

HSP 1 Score: 115.931 bits (289), Expect = 1.385e-23
Identity = 107/377 (28.38%), Postives = 187/377 (49.60%), Query Frame = 1 
Query:   16 DLLLKKRKAITNKSKIDACIEIAILHTENCDIQQAISEYKEVLELADECDDLNMKGKAYRYIGESLLDLHQPMEALEYIKEYLKVAQKSKDIFEIQRAYVTIGRCFLDFSEIVKNPTVKQTVAIKSENAFVKSLQLCQQISENEENLISNYKSITELTNE-----LAEMRAVSLFNLGLANRVKSDEKSFRTA--ERYFIQCSNISVKHKLNEMLLRSTFQQFDL--NYSQSLNQWTIANSGKSRLIVEESLKVLRK--NFGLMTGIPFTSV---MKKIAKEIHELEAQCLIVAERFHKAAKKFRNLMRRSHNCRSNYRMKMLSAIKLSE---KLPRA---------TNNEDIILIGQIYDELGIQLVAGKYYEVAL 1068
            +LL ++ +A + K + D  +EIA+LHTE+ D   A+ E+ ++LEL     D      ++R++ +  ++L +  +A+ +  +YL++A +  +  E QRA+VT+GRCFL+ SE +K+    +     +  A + S+Q+                 ITE T E     L EMRAVSL NLG   R + +    RTA  ER F QC +++ K++L ++L R+ +Q  DL  N   + +   +  SG   L+    L+ +       L++ +  T+V    K++ K + E  AQ  +   +F KAAK +R L   + N     R  +   ++LS+    +P +         T +     +G IY  L +  +A ++Y+  L
Sbjct:   17 ELLEQRNRAKSVKEEADLTLEIAVLHTESGDHTHALREFTKLLELWQSKGDKLQCAISHRFLADCCIELDEYDQAISHTNQYLRLATELGNKLEQQRAFVTLGRCFLNRSEAMKDGDFVEKNLKSAAQALLNSIQM-----------------ITEFTGELDSKQLGEMRAVSLLNLGQVFRAQRE----RTAALER-FTQCISLARKYQLQKLLFRACYQIADLSMNTPPTHSYEPVNRSGLITLMNSAPLRNVMTVLQMALVSPMAKTNVDQESKELIKSLRESMAQIYLSIGQFRKAAKVYRLLKLHNPNSSDYCRQLIQKCMRLSKLMYTIPESVPFDLETFRTTSRAHERMGDIYSGLEMHGLALRHYQFML 371
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. TrEMBL
Match: A0A0V0JC59 (Uncharacterized protein OS=Schistocephalus solidus OX=70667 GN=TR120419 PE=4 SV=1)

HSP 1 Score: 117.087 bits (292), Expect = 1.497e-23
Identity = 104/358 (29.05%), Postives = 163/358 (45.53%), Query Frame = 1 
Query:   10 LKDLLLKKRKAITNKSKIDACIEIAILHTENCDIQQAISEYKEVLELADECDDLNMKGKAYRYIGESLLDLHQPMEALEYIKEYLKVAQKSKDIFEIQRAYVTIGRCFLDFSEIVKNPTVKQTVAIKSENAFVKSLQLCQQISENEENLISNYKSITELTNELAEMRAVSLFNLGLANRVKSDEKSFRTAERYFIQCSNISVKHKLNEMLLRSTFQQFDLNYSQSLNQWTIANSGKSRLIVEESLKVLRKNF---------GLMTGIPFTSVMKK----IAKEIHELEAQCLIVAERFHKAAKKFRNLMRRSHNCRSNYRMKMLSAIKLSEKLPR-----ATNNEDIILIGQIYDELG 1029
            L+ LL ++    ++  +    +EIA+ ++E  D   A+ EYK ++ L +   D       YR + E  L+L    EA+ Y   YLK  ++  ++ E QRA+VTIGRCFL  S+ +KN  + +           KSL   QQ   N    IS+ K ++    E AEM+ VSL NLG   R     +S R  ER F QC N+S K+ L ++L RS +Q  +L    SL  W   +     L   E L V  K +           +   P  S + K    + + + EL  Q  +      ++AK ++ L          YR     A+K+   L +     +T  ED++ + ++Y+ LG
Sbjct:    3 LQRLLSQRDACHSSTERCALTLEIALCYSEQGDFSAAVEEYKTLVVLLEAGTDRLKTALCYRSLSECFLELSNFNEAIRYASMYLKATREIHNLLEQQRAFVTIGRCFLCRSDNLKNGELAR-----------KSLMAAQQALINSIKCISSLKELS--ATEAAEMKGVSLLNLGQVLRSLGQTESAR--ER-FEQCINLSRKYSLLKILFRSVYQHAEL----SLLSW--PDFRGQILRPSELLTVTEKGYLDNAVFLCSKTLRSYPARSCLDKETKMLRQNLEELLGQLYLAVGDCKRSAKVYKRLALAYPQTSQTYRSACRKALKMHSLLTKIQQFISTAAEDLLQVSRLYESLG 338
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. TrEMBL
Match: A0A0R3T590 (Uncharacterized protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS2227 PE=4 SV=1)

HSP 1 Score: 117.087 bits (292), Expect = 1.635e-23
Identity = 100/358 (27.93%), Postives = 175/358 (48.88%), Query Frame = 1 
Query:   13 KDLLLKKRKAITNKSKIDACIEIAILHTENCDIQQAISEYKEVLEL---ADECDDLNMKGKAYRYIGESLLDLHQPMEALEYIKEYLKVAQKSKDIFEIQRAYVTIGRCFLDFSEIVKNPTVKQTVAIKSENAFVKSLQLCQQISENEENLISNYKSITELTNELAEMRAVSLFNLGLANRVKSDEKSFRTAERYFIQCSNISVKHKLNEMLLRSTFQQFDLNYSQSLNQWTIANSGKSR---LIVEESLKVLRKNFGLMTGI--PFTSV------MKKIAKEIHELEAQCLIVAERFHKAAKKFRNLMRRSHNCRSNYRMKMLSAIKLSEKLPR-----ATNNEDIILIGQIYDELG 1029
            + L+ +++ A T + ++D+ + +AI H E  +   AIS YK +L L    D  D+L +    +R I E  L+L    EA+++  +YLK+++   +  E QRAYVTIGRCF   S+   N  V +   + ++ A + S++L  Q++           S+T +  + AEM+AVSL NLG A     D   F +A   F QC NI+ KH L  +L R+ FQ  ++     L+ W +    + R   L+  E   ++ K   L +    P  S        K   + + +L AQ  +    +  AAK +R + R   +   NY+     A++L + + R       + + ++ + ++Y+++G
Sbjct:   63 RQLIKQQQNAKTFRERVDSTLALAIFHFEQSNFSTAISVYKTLLSLYESHDSRDELQI-ALTHRAIAECNLELGDFNEAIKHTSQYLKISKVINNKLEQQRAYVTIGRCFQCRSDSASNGEVARKSLLAAQQAILNSIKLTNQLT-----------SLTSV--QQAEMKAVSLLNLGHALCSMGD---FESAASRFDQCINIARKHALRSILFRAVFQNCEI----PLHHWPVIAQSRLRHTDLLNHEESSIIAKAISLCSQTLKPAGSQNCLSKETKTYRRNLEDLLAQLYVAKSSYRTAAKVYRQISRADSSSSLNYKELCGKALRLDKIISRFQYSDCESVDGMLQVSKLYEKMG 399
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Cavefish
Match: tonsl (tonsoku like, DNA repair protein [Source:NCBI gene;Acc:103023933])

HSP 1 Score: 66.2402 bits (160), Expect = 6.602e-11
Identity = 65/225 (28.89%), Postives = 107/225 (47.56%), Query Frame = 1 
Query:   52 KSKIDACIEIAILHTENCDIQQAISEYKEVLELADECDDLNMKGKAYRYIGESLLDLHQPMEALEYIKEYLKVAQKSKDIFEIQRAYVTIGRCFLDFSEIVKN-PTVKQTVAIKSENAFVKSLQLCQQISENEENLISNYKSITELTNELAEMRAVSLFNLGLANRVKSDEKSFRTAERYFIQCSNISVKHKLNEMLLRSTFQQFDLNYSQSLNQWTIANSGKSR 723
            K +   C ++  +  ++ D Q AI E+++ L L+    D+     A R IGE   +L     AL+Y + +L +A+   D  E QRA  TIGR +L   +  ++  ++KQ     +E+AF KSL +   ++E+ E  +S          E +EMRA  L NLG    V    K  +    +  Q   IS K+ L E L R+ F   ++++    +  +I    KS+
Sbjct:   24 KEEASLCNQLGEVLAKSGDYQAAIEEHRQELALSQVLHDVIGCAVANRKIGECYAELGNIATALKYQRRHLDLARSVNDAVEEQRALATIGRTYLFLHDTDQSLDSLKQ-----AEDAFKKSLAI---VNEHLEGRVS--------ARERSEMRARLLLNLGF---VCDGLKDPQRCNEFIRQSIYISEKNNLLEDLYRANFNLGNIHFRNGQHSLSIRCFEKSK 229
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Sea Lamprey
Match: tonsl (tonsoku-like, DNA repair protein [Source:NCBI gene;Acc:492655])

HSP 1 Score: 60.8474 bits (146), Expect = 5.594e-10
Identity = 61/217 (28.11%), Postives = 108/217 (49.77%), Query Frame = 1 
Query:   28 KKRKAITNKSKIDACIEIAILHTENCDIQQAISEYKEVLELADECDDLNMKGKAYRYIGESLLDLHQPMEALEYIKEYLKVAQKSKDIFEIQRAYVTIGRCFLDFSEIVKNPTVKQTVAIKSENAFVKSLQLCQQISENEENLISNYKSITELT-NELAEMRAVSLFNLGLANRVKSDEKSFRTAERYFIQCSNISVKHKLNEMLLRSTFQQFDLNY 675
            K +KA   + +   C  I  L   +   ++AI E+++ L+L++  +D+     A R IGES   L     AL++ +++L++++   +  E QRA  TIGR +L + +   +P   + +  K+E AF+ SL++  Q  E             EL   EL EMRA    NLGL    + D      ++++F +   ++ K+ L E L R+ F   +L++
Sbjct:   16 KAQKANNLREEATICNLIGDLLASHGHYKEAIEEHQQELQLSEALNDVIGTAVANRKIGESWAMLENYSRALKHQQKHLELSRSMGNRVEEQRALATIGRTYLFYCDT--DPENTEALQ-KAEEAFLASLKIVDQQLE------------VELPWKELNEMRARLFLNLGLVYDHRQDAAR---SQKFFRKSIFLAEKNNLTEDLYRANFILGNLHF 214
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Sea Lamprey
Match: tonsl (tonsoku-like, DNA repair protein [Source:NCBI gene;Acc:492655])

HSP 1 Score: 60.8474 bits (146), Expect = 6.009e-10
Identity = 61/217 (28.11%), Postives = 108/217 (49.77%), Query Frame = 1 
Query:   28 KKRKAITNKSKIDACIEIAILHTENCDIQQAISEYKEVLELADECDDLNMKGKAYRYIGESLLDLHQPMEALEYIKEYLKVAQKSKDIFEIQRAYVTIGRCFLDFSEIVKNPTVKQTVAIKSENAFVKSLQLCQQISENEENLISNYKSITELT-NELAEMRAVSLFNLGLANRVKSDEKSFRTAERYFIQCSNISVKHKLNEMLLRSTFQQFDLNY 675
            K +KA   + +   C  I  L   +   ++AI E+++ L+L++  +D+     A R IGES   L     AL++ +++L++++   +  E QRA  TIGR +L + +   +P   + +  K+E AF+ SL++  Q  E             EL   EL EMRA    NLGL    + D      ++++F +   ++ K+ L E L R+ F   +L++
Sbjct:   16 KAQKANNLREEATICNLIGDLLASHGHYKEAIEEHQQELQLSEALNDVIGTAVANRKIGESWAMLENYSRALKHQQKHLELSRSMGNRVEEQRALATIGRTYLFYCDT--DPENTEALQ-KAEEAFLASLKIVDQQLE------------VELPWKELNEMRARLFLNLGLVYDHRQDAA---RSQKFFRKSIFLAEKNNLTEDLYRANFILGNLHF 214
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Sea Lamprey
Match: tonsl (tonsoku-like, DNA repair protein [Source:NCBI gene;Acc:492655])

HSP 1 Score: 60.8474 bits (146), Expect = 6.522e-10
Identity = 61/217 (28.11%), Postives = 108/217 (49.77%), Query Frame = 1 
Query:   28 KKRKAITNKSKIDACIEIAILHTENCDIQQAISEYKEVLELADECDDLNMKGKAYRYIGESLLDLHQPMEALEYIKEYLKVAQKSKDIFEIQRAYVTIGRCFLDFSEIVKNPTVKQTVAIKSENAFVKSLQLCQQISENEENLISNYKSITELT-NELAEMRAVSLFNLGLANRVKSDEKSFRTAERYFIQCSNISVKHKLNEMLLRSTFQQFDLNY 675
            K +KA   + +   C  I  L   +   ++AI E+++ L+L++  +D+     A R IGES   L     AL++ +++L++++   +  E QRA  TIGR +L + +   +P   + +  K+E AF+ SL++  Q  E             EL   EL EMRA    NLGL    + D      ++++F +   ++ K+ L E L R+ F   +L++
Sbjct:   16 KAQKANNLREEATICNLIGDLLASHGHYKEAIEEHQQELQLSEALNDVIGTAVANRKIGESWAMLENYSRALKHQQKHLELSRSMGNRVEEQRALATIGRTYLFYCDT--DPENTEALQ-KAEEAFLASLKIVDQQLE------------VELPWKELNEMRARLFLNLGLVYDHRQDAAR---SQKFFRKSIFLAEKNNLTEDLYRANFILGNLHF 214
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Nematostella
Match: EDO37052 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SGW7])

HSP 1 Score: 59.3066 bits (142), Expect = 2.455e-9
Identity = 50/182 (27.47%), Postives = 92/182 (50.55%), Query Frame = 1 
Query:  112 QQAISEYKEVLELADECDDLNMKGKAYRYIGESLLDLHQPMEALEYIKEYLKVAQKSKDIFEIQRAYVTIGRC-FLDFSEIVKNPTVKQTVAIKSENAFVKSLQLCQQISENEENLISNYKSITELTNELAEMRAVSLFNLGLANRVKSDEKSFRTAERYFIQCSNISVKHKLNEMLLRSTF 654
            ++AI E+K+ ++L++  +D      A+R +GE L  L +  EAL +   +L++A+ + ++ E QRA  TIGR  F+     V +    +   ++++ AF+ SL++C  + E+         +I +   EL EMR+    NLGL    ++D    + A ++  +   IS    L E   R  +
Sbjct:   35 EKAIKEHKQEVQLSEAVNDDIGSAIAHRKVGECLSALGKYKEALFHQNLHLQLAKTANNLVEQQRALATIGRTWFVHADSPVNDDQEVEESLVEAQKAFLLSLEICDALQED--------GNIPD--KELLEMRSRLYLNLGLVYESRND---IQNARKFIDKALAISRDQNLRETEFRCHY 203
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Medaka
Match: tonsl (tonsoku like, DNA repair protein [Source:NCBI gene;Acc:101173594])

HSP 1 Score: 65.4698 bits (158), Expect = 1.261e-10
Identity = 64/218 (29.36%), Postives = 105/218 (48.17%), Query Frame = 1 
Query:   10 LKDLLLKKRKAITN---KSKIDACIEIAILHTENCDIQQAISEYKEVLELADECDDLNMKGKAYRYIGESLLDLHQPMEALEYIKEYLKVAQKSKDIFEIQRAYVTIGRCFLDFSEIVKNPTVKQTVAIKSENAFVKSLQLCQQISENEENLISNYKSITELTNELAEMRAVSLFNLGLANRVKSDEKSFRTAERYFIQCSNISVKHKLNEMLLRSTF 654
            +K L   K KA  +   K + + C ++  L + N D + AI E+++ L L++  DD+  +  A R IGE   ++     AL++ + +L +A    D  E+QRA  TIGR +L   E  ++ +  +    K+E+AF KSL +       +E L       T    E+AEM+A    NLG+      + K       +  +   I+VK +L E L R+ F
Sbjct:    7 IKQLQKAKSKAQASNNLKEEANICNQLGELLSRNGDYEAAIREHQQELSLSESLDDVIGRAVANRKIGECYAEMGNIKAALKHQQCHLDLAHSVGDHAEVQRALATIGRTYLFRYESDQSKSSLK----KAEDAFRKSLAIV------DERL-----GGTVPDREIAEMKARLFLNLGIVCDHLGESKH---CSEFIRRSVFIAVKSQLLEDLYRANF 206
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Planmine SMEST
Match: SMESG000012441.1 (SMESG000012441.1)

HSP 1 Score: 862.833 bits (2228), Expect = 0.000e+0
Identity = 497/497 (100.00%), Postives = 497/497 (100.00%), Query Frame = 1 
Query:  175 MKGKAYRYIGESLLDLHQPMEALEYIKEYLKVAQKSKDIFEIQRAYVTIGRCFLDFSEIVKNPTVKQTVAIKSENAFVKSLQLCQQISENEENLISNYKSITELTNELAEMRAVSLFNLGLANRVKSDEKSFRTAERYFIQCSNISVKHKLNEMLLRSTFQQFDLNYSQSLNQWTIANSGKSRLIVEESLKVLRKNFGLMTGIPFTSVMKKIAKEIHELEAQCLIVAERFHKAAKKFRNLMRRSHNCRSNYRMKMLSAIKLSEKLPRATNNEDIILIGQIYDELGIQLVAGKYYEVALQKVRTSQRELYYKLVNRLININQSIGHYNENIKLLESKLRWKLERNEAPICCKIIEQLLDCYLRSGAAFNKLDRVIFIAQQLDSLAISTGRSNIKISAVKSIISLYEELGTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMAETXXXXXXXXXXXXXXXQIEELEAVGKRVKPGNNNSFIK 1665
            MKGKAYRYIGESLLDLHQPMEALEYIKEYLKVAQKSKDIFEIQRAYVTIGRCFLDFSEIVKNPTVKQTVAIKSENAFVKSLQLCQQISENEENLISNYKSITELTNELAEMRAVSLFNLGLANRVKSDEKSFRTAERYFIQCSNISVKHKLNEMLLRSTFQQFDLNYSQSLNQWTIANSGKSRLIVEESLKVLRKNFGLMTGIPFTSVMKKIAKEIHELEAQCLIVAERFHKAAKKFRNLMRRSHNCRSNYRMKMLSAIKLSEKLPRATNNEDIILIGQIYDELGIQLVAGKYYEVALQKVRTSQRELYYKLVNRLININQSIGHYNENIKLLESKLRWKLERNEAPICCKIIEQLLDCYLRSGAAFNKLDRVIFIAQQLDSLAISTGRSNIKISAVKSIISLYEELGTEALKVELVKEREKLKHLELNSESSEENEELNDEEDLELSDLEISENDMAETLSSDSDIDLRSLSESQIEELEAVGKRVKPGNNNSFIK
Sbjct:    1 MKGKAYRYIGESLLDLHQPMEALEYIKEYLKVAQKSKDIFEIQRAYVTIGRCFLDFSEIVKNPTVKQTVAIKSENAFVKSLQLCQQISENEENLISNYKSITELTNELAEMRAVSLFNLGLANRVKSDEKSFRTAERYFIQCSNISVKHKLNEMLLRSTFQQFDLNYSQSLNQWTIANSGKSRLIVEESLKVLRKNFGLMTGIPFTSVMKKIAKEIHELEAQCLIVAERFHKAAKKFRNLMRRSHNCRSNYRMKMLSAIKLSEKLPRATNNEDIILIGQIYDELGIQLVAGKYYEVALQKVRTSQRELYYKLVNRLININQSIGHYNENIKLLESKLRWKLERNEAPICCKIIEQLLDCYLRSGAAFNKLDRVIFIAQQLDSLAISTGRSNIKISAVKSIISLYEELGTEALKVELVKEREKLKHLELNSESSEENEELNDEEDLELSDLEISENDMAETLSSDSDIDLRSLSESQIEELEAVGKRVKPGNNNSFIK 497
The following BLAST results are available for this feature:
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 1
Match NameE-valueIdentityDescription
TONSL7.071e-927.06tonsoku like, DNA repair protein [Source:HGNC Symb... [more]
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BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
tonsl1.970e-828.44tonsoku-like, DNA repair protein [Source:NCBI gene... [more]
tonsl2.067e-828.44tonsoku-like, DNA repair protein [Source:NCBI gene... [more]
tonsl2.067e-828.44tonsoku-like, DNA repair protein [Source:NCBI gene... [more]
tonsl3.794e-730.05tonsoku-like, DNA repair protein [Source:NCBI gene... [more]
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BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Tonsl1.535e-728.21tonsoku-like, DNA repair protein [Source:MGI Symbo... [more]
Tonsl2.821e-728.21tonsoku-like, DNA repair protein [Source:MGI Symbo... [more]
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BLAST of ANK_REP_REGION domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q96HA7|TONSL_HUMAN3.396e-827.06Tonsoku-like protein OS=Homo sapiens OX=9606 GN=TO... [more]
sp|D4A615|TONSL_RAT1.117e-727.92Tonsoku-like protein OS=Rattus norvegicus OX=10116... [more]
sp|A9JR78|TONSL_DANRE3.152e-727.98Tonsoku-like protein OS=Danio rerio OX=7955 GN=ton... [more]
sp|Q0P5G1|TONSL_BOVIN6.947e-727.65Tonsoku-like protein OS=Bos taurus OX=9913 GN=TONS... [more]
sp|Q6NZL6|TONSL_MOUSE2.077e-628.21Tonsoku-like protein OS=Mus musculus OX=10090 GN=T... [more]
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BLAST of ANK_REP_REGION domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A504YA073.917e-2728.46Nalp (Nacht leucine rich repeat and pyrin domain c... [more]
A0A4E0RVD88.291e-2627.59ANK_REP_REGION domain-containing protein OS=Fascio... [more]
A0A183A0T01.385e-2328.38Uncharacterized protein OS=Echinostoma caproni OX=... [more]
A0A0V0JC591.497e-2329.05Uncharacterized protein OS=Schistocephalus solidus... [more]
A0A0R3T5901.635e-2327.93Uncharacterized protein OS=Rodentolepis nana OX=10... [more]
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BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
tonsl6.602e-1128.89tonsoku like, DNA repair protein [Source:NCBI gene... [more]
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BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
tonsl5.594e-1028.11tonsoku-like, DNA repair protein [Source:NCBI gene... [more]
tonsl6.009e-1028.11tonsoku-like, DNA repair protein [Source:NCBI gene... [more]
tonsl6.522e-1028.11tonsoku-like, DNA repair protein [Source:NCBI gene... [more]
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BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO370522.455e-927.47Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
tonsl1.261e-1029.36tonsoku like, DNA repair protein [Source:NCBI gene... [more]
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BLAST of ANK_REP_REGION domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000012441.10.000e+0100.00SMESG000012441.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30021240 ID=SMED30021240|Name=ANK_REP_REGION domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1665bp
ATGAGCAATTTAAAAGATTTATTACTGAAAAAACGTAAGGCAATTACCAA
TAAATCAAAAATTGATGCTTGCATCGAAATTGCAATTTTACATACTGAAA
ATTGTGATATTCAACAAGCTATATCTGAATATAAAGAAGTATTGGAATTA
GCCGATGAATGTGATGATTTAAATATGAAAGGCAAGGCTTATCGATATAT
TGGAGAAAGTTTGTTAGATTTGCACCAACCAATGGAAGCGCTTGAATATA
TCAAAGAATATTTAAAAGTTGCACAAAAATCCAAAGATATATTTGAAATC
CAAAGAGCCTATGTCACTATAGGTCGATGCTTTCTTGATTTTTCTGAAAT
TGTAAAAAATCCAACTGTCAAACAAACTGTTGCAATCAAATCTGAAAACG
CATTTGTTAAAAGTCTTCAATTGTGTCAGCAGATTTCCGAAAATGAAGAA
AACTTGATTAGCAACTACAAATCGATTACTGAATTAACTAATGAATTAGC
AGAAATGCGAGCGGTTTCCTTGTTCAACCTAGGTCTCGCCAATCGAGTAA
AATCTGATGAAAAATCATTTAGAACCGCTGAAAGATATTTCATTCAATGC
AGCAATATTTCAGTGAAACATAAATTAAATGAAATGCTCCTCCGATCCAC
ATTCCAACAATTCGATCTGAATTATTCTCAATCTCTCAACCAGTGGACGA
TTGCCAATTCCGGCAAATCCCGTCTCATTGTTGAGGAATCTTTGAAGGTT
CTCAGAAAGAATTTCGGACTAATGACTGGAATACCTTTTACGAGTGTCAT
GAAGAAGATTGCCAAGGAAATTCACGAACTCGAGGCACAATGTTTGATAG
TTGCCGAGAGATTCCACAAAGCTGCTAAGAAATTCAGAAATTTGATGAGA
CGATCTCACAATTGTCGCAGTAACTATCGAATGAAAATGCTTTCTGCAAT
TAAATTGAGTGAAAAATTGCCTCGTGCTACTAATAATGAAGATATTATTT
TGATTGGACAGATTTATGATGAACTAGGAATTCAATTGGTCGCCGGGAAG
TATTACGAAGTTGCTTTGCAAAAAGTGAGAACATCTCAAAGGGAATTATA
TTACAAGTTAGTAAACCGTCTCATTAATATTAATCAATCTATCGGCCATT
ATAATGAAAATATTAAACTACTCGAGTCGAAATTGAGATGGAAACTGGAA
CGAAATGAAGCTCCTATTTGTTGTAAGATAATCGAACAGTTGCTGGATTG
TTATTTACGATCTGGGGCTGCTTTCAATAAACTCGATCGAGTAATTTTTA
TCGCCCAACAGCTGGATTCCTTAGCTATTTCGACAGGGCGATCAAATATA
AAAATTTCAGCTGTCAAATCCATTATCAGTCTTTACGAGGAACTTGGAAC
TGAAGCACTGAAAGTCGAACTTGTAAAGGAAAGAGAAAAATTAAAACACC
TAGAGCTAAATTCGGAATCCAGTGAGGAAAATGAGGAATTGAATGATGAA
GAAGATCTGGAGTTATCTGATCTGGAGATATCAGAAAATGATATGGCAGA
GACTTTGTCATCCGATTCTGATATTGACTTACGCTCACTGAGTGAAAGTC
AAATCGAAGAACTGGAAGCAGTTGGAAAAAGAGTGAAGCCTGGAAACAAT
AACTCTTTTATTAAG
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protein sequence of SMED30021240-orf-1

>SMED30021240-orf-1 ID=SMED30021240-orf-1|Name=SMED30021240-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=555bp
MSNLKDLLLKKRKAITNKSKIDACIEIAILHTENCDIQQAISEYKEVLEL
ADECDDLNMKGKAYRYIGESLLDLHQPMEALEYIKEYLKVAQKSKDIFEI
QRAYVTIGRCFLDFSEIVKNPTVKQTVAIKSENAFVKSLQLCQQISENEE
NLISNYKSITELTNELAEMRAVSLFNLGLANRVKSDEKSFRTAERYFIQC
SNISVKHKLNEMLLRSTFQQFDLNYSQSLNQWTIANSGKSRLIVEESLKV
LRKNFGLMTGIPFTSVMKKIAKEIHELEAQCLIVAERFHKAAKKFRNLMR
RSHNCRSNYRMKMLSAIKLSEKLPRATNNEDIILIGQIYDELGIQLVAGK
YYEVALQKVRTSQRELYYKLVNRLININQSIGHYNENIKLLESKLRWKLE
RNEAPICCKIIEQLLDCYLRSGAAFNKLDRVIFIAQQLDSLAISTGRSNI
KISAVKSIISLYEELGTEALKVELVKEREKLKHLELNSESSEENEELNDE
EDLELSDLEISENDMAETLSSDSDIDLRSLSESQIEELEAVGKRVKPGNN
NSFIK
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000421tail
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR019734TPR_repeat
IPR011990TPR-like_helical_dom_sf
IPR013026TPR-contain_dom
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
GO:0042393histone binding
Vocabulary: biological process
TermDefinition
GO:0000724double-strand break repair via homologous recombination
GO:0006281DNA repair
GO:0006974cellular response to DNA damage stimulus
GO:0031297replication fork processing
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
GO:0005654nucleoplasm
GO:0005662DNA replication factor A complex
GO:0005737cytoplasm
GO:0016604nuclear body
GO:0035101FACT complex
GO:0042555MCM complex
GO:0043596nuclear replication fork
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 467..494
NoneNo IPR availablePANTHERPTHR46358FAMILY NOT NAMEDcoord: 18..520
IPR019734Tetratricopeptide repeatSMARTSM00028tpr_5coord: 61..94
e-value: 25.0
score: 11.5
coord: 21..54
e-value: 2.7
score: 17.0
IPR011990Tetratricopeptide-like helical domain superfamilyGENE3DG3DSA:1.25.40.10coord: 5..204
e-value: 1.3E-15
score: 59.5
IPR011990Tetratricopeptide-like helical domain superfamilySUPERFAMILYSSF48452TPR-likecoord: 18..168
IPR013026Tetratricopeptide repeat-containing domainPROSITEPS50293TPR_REGIONcoord: 21..94
score: 8.991