Neuroepithelial cell transforming 1

Overview
NameNeuroepithelial cell transforming 1
Smed IDSMED30021221
Length (bp)1856
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Neuroepithelial cell transforming 1 (SMED30021221) t-SNE clustered cells

Violin plots show distribution of expression levels for Neuroepithelial cell transforming 1 (SMED30021221) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30021221

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
whole organismSMED30021221SMESG000035468.1 Contig29728newmark_estsPMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
whole organismSMED30021221SMESG000035468.1 Contig29728uc_Smed_v2PMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
reproductive organSMED30021221SMESG000035468.1 Contig29728newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30021221SMESG000035468.1 Contig29728uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Human
Match: NET1 (neuroepithelial cell transforming 1 [Source:HGNC Symbol;Acc:HGNC:14592])

HSP 1 Score: 157.918 bits (398), Expect = 6.431e-51
Identity = 101/278 (36.33%), Postives = 149/278 (53.60%), Query Frame = 1 
Query:  910 YCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRLTLLSNFIPEIEFDDHNDYNERALEDTFASNDKYEQSPYDGRLLKNSQTILQTSQLEEKQLWLNTLRKVVA 1740
            YC++   +KA L++K++D  + +FLQ C  S FSRKLDLW+FLD PRSRL+KYPLL + ILK +  EH D   L D +   + +L  ++ K GE  C +Y+ KL++L++ Q    ++   VL+  G +   RS   HK++ FLF++ILV T+       E   Y VY  P+P  +L+LE++ DG++RM GSFR  FS+   +KN+FR          I F D +     A   T  +ND +                        KQ W N +R  +A
Sbjct:  212 YCSNQLAAKALLDQKKQDPRVQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILKHTPKEHPDVQLLEDAILIIQGVLSDINLKKGESECQYYIDKLEYLDEKQRDPRIEASKVLLCHGEL---RSKSGHKLYIFLFQDILVLTRPVTRN--ERHSYQVYRQPIPVQELVLEDLQDGDVRMGGSFRGAFSNSEKAKNIFR----------IRFHDPSP----AQSHTLQANDVF-----------------------HKQQWFNCIRAAIA 447

HSP 2 Score: 64.3142 bits (155), Expect = 6.431e-51
Identity = 39/147 (26.53%), Postives = 72/147 (48.98%), Query Frame = 3 
Query:  453 YGITTAAIII-GRHDSTSSTHSICKQAWIETENGRR------------LGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWVNIGNS 854
            +G T  +  + G H S +S      ++ + T   RR            +  +L+ +EI RQ  I+E+  GE D I DLK   K Y +PM KL ++   +  +IF +++  IP++E  +  +      +G ++ IG +++ W+   N+
Sbjct:   62 FGQTIQSFTLRGDHRSPASAQKFSSRSTVPTPAKRRSSALWSEMLDITMKESLTTREIRRQEAIYEMSRGEQDLIEDLKLARKAYHDPMLKLSIMSEEELTHIFGDLDSYIPLHEDLLTRIGEATKPDGTVEQIGHILVSWLPRLNA 208
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Human
Match: NET1 (neuroepithelial cell transforming 1 [Source:HGNC Symbol;Acc:HGNC:14592])

HSP 1 Score: 157.918 bits (398), Expect = 6.809e-51
Identity = 101/278 (36.33%), Postives = 149/278 (53.60%), Query Frame = 1 
Query:  910 YCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRLTLLSNFIPEIEFDDHNDYNERALEDTFASNDKYEQSPYDGRLLKNSQTILQTSQLEEKQLWLNTLRKVVA 1740
            YC++   +KA L++K++D  + +FLQ C  S FSRKLDLW+FLD PRSRL+KYPLL + ILK +  EH D   L D +   + +L  ++ K GE  C +Y+ KL++L++ Q    ++   VL+  G +   RS   HK++ FLF++ILV T+       E   Y VY  P+P  +L+LE++ DG++RM GSFR  FS+   +KN+FR          I F D +     A   T  +ND +                        KQ W N +R  +A
Sbjct:  266 YCSNQLAAKALLDQKKQDPRVQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILKHTPKEHPDVQLLEDAILIIQGVLSDINLKKGESECQYYIDKLEYLDEKQRDPRIEASKVLLCHGEL---RSKSGHKLYIFLFQDILVLTRPVTRN--ERHSYQVYRQPIPVQELVLEDLQDGDVRMGGSFRGAFSNSEKAKNIFR----------IRFHDPSP----AQSHTLQANDVF-----------------------HKQQWFNCIRAAIA 501

HSP 2 Score: 64.3142 bits (155), Expect = 6.809e-51
Identity = 41/157 (26.11%), Postives = 75/157 (47.77%), Query Frame = 3 
Query:  453 YGITTAAIII-GRHDSTSSTHSICKQAWIETENGRR------------LGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWVNIGNSLQLNHVNDLV 884
            +G T  +  + G H S +S      ++ + T   RR            +  +L+ +EI RQ  I+E+  GE D I DLK   K Y +PM KL ++   +  +IF +++  IP++E  +  +      +G ++ IG +++ W+   N+ +    N L 
Sbjct:  116 FGQTIQSFTLRGDHRSPASAQKFSSRSTVPTPAKRRSSALWSEMLDITMKESLTTREIRRQEAIYEMSRGEQDLIEDLKLARKAYHDPMLKLSIMSEEELTHIFGDLDSYIPLHEDLLTRIGEATKPDGTVEQIGHILVSWLPRLNAYRGYCSNQLA 272
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Human
Match: ARHGEF3 (Rho guanine nucleotide exchange factor 3 [Source:HGNC Symbol;Acc:HGNC:683])

HSP 1 Score: 153.68 bits (387), Expect = 7.452e-49
Identity = 86/209 (41.15%), Postives = 129/209 (61.72%), Query Frame = 1 
Query:  910 YCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRLT 1533
            YC++   +KA L+ K++D  + +FLQ C  S FSRKLDLWNFLD PRSRL+KYPLL   IL+ + +++ D   L + +   + I+  ++ KTGE  C +Y  +L +LE+ Q  +L+ +  VL   G +K  R V   K+H FLF+E+LV T+       E   Y +Y  P+P   L+LE++ DGE+R+ GS R  FS++   KN FR++
Sbjct:  246 YCSNQVAAKALLDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHTPNDNPDQQHLEEAINIIQGIVAEINTKTGESECRYYKERLLYLEEGQKDSLIDSSRVLCCHGELKNNRGV---KLHVFLFQEVLVITRAVTHN--EQLCYQLYRQPIPVKDLLLEDLQDGEVRLGGSLRGAFSNNERIKNFFRVS 449

HSP 2 Score: 61.6178 bits (148), Expect = 7.452e-49
Identity = 38/124 (30.65%), Postives = 65/124 (52.42%), Query Frame = 3 
Query:  483 GRHDSTSSTHSICKQAWIETENGRRLGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWVNIGNS 854
             R+ + SST     + W ET +   +   L+ +EI+RQ  I EL  GE D I DLK   K Y +PM KL ++   +   IF  ++ +IP++E  +  L   +  +G  + +G +++ W+   +S
Sbjct:  120 SRNAAPSSTKRRDSKLWSETFDVC-VNQMLTSKEIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQELNQIFGTLDSLIPLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSS 242
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Human
Match: ARHGEF3 (Rho guanine nucleotide exchange factor 3 [Source:HGNC Symbol;Acc:HGNC:683])

HSP 1 Score: 154.066 bits (388), Expect = 9.020e-49
Identity = 86/209 (41.15%), Postives = 129/209 (61.72%), Query Frame = 1 
Query:  910 YCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRLT 1533
            YC++   +KA L+ K++D  + +FLQ C  S FSRKLDLWNFLD PRSRL+KYPLL   IL+ + +++ D   L + +   + I+  ++ KTGE  C +Y  +L +LE+ Q  +L+ +  VL   G +K  R V   K+H FLF+E+LV T+       E   Y +Y  P+P   L+LE++ DGE+R+ GS R  FS++   KN FR++
Sbjct:  214 YCSNQVAAKALLDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHTPNDNPDQQHLEEAINIIQGIVAEINTKTGESECRYYKERLLYLEEGQKDSLIDSSRVLCCHGELKNNRGV---KLHVFLFQEVLVITRAVTHN--EQLCYQLYRQPIPVKDLLLEDLQDGEVRLGGSLRGAFSNNERIKNFFRVS 417

HSP 2 Score: 61.2326 bits (147), Expect = 9.020e-49
Identity = 38/124 (30.65%), Postives = 65/124 (52.42%), Query Frame = 3 
Query:  483 GRHDSTSSTHSICKQAWIETENGRRLGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWVNIGNS 854
             R+ + SST     + W ET +   +   L+ +EI+RQ  I EL  GE D I DLK   K Y +PM KL ++   +   IF  ++ +IP++E  +  L   +  +G  + +G +++ W+   +S
Sbjct:   88 SRNAAPSSTKRRDSKLWSETFDVC-VNQMLTSKEIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQELNQIFGTLDSLIPLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSS 210
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Human
Match: ARHGEF3 (Rho guanine nucleotide exchange factor 3 [Source:HGNC Symbol;Acc:HGNC:683])

HSP 1 Score: 154.066 bits (388), Expect = 9.252e-49
Identity = 86/209 (41.15%), Postives = 129/209 (61.72%), Query Frame = 1 
Query:  910 YCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRLT 1533
            YC++   +KA L+ K++D  + +FLQ C  S FSRKLDLWNFLD PRSRL+KYPLL   IL+ + +++ D   L + +   + I+  ++ KTGE  C +Y  +L +LE+ Q  +L+ +  VL   G +K  R V   K+H FLF+E+LV T+       E   Y +Y  P+P   L+LE++ DGE+R+ GS R  FS++   KN FR++
Sbjct:  185 YCSNQVAAKALLDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHTPNDNPDQQHLEEAINIIQGIVAEINTKTGESECRYYKERLLYLEEGQKDSLIDSSRVLCCHGELKNNRGV---KLHVFLFQEVLVITRAVTHN--EQLCYQLYRQPIPVKDLLLEDLQDGEVRLGGSLRGAFSNNERIKNFFRVS 388

HSP 2 Score: 61.2326 bits (147), Expect = 9.252e-49
Identity = 38/124 (30.65%), Postives = 65/124 (52.42%), Query Frame = 3 
Query:  483 GRHDSTSSTHSICKQAWIETENGRRLGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWVNIGNS 854
             R+ + SST     + W ET +   +   L+ +EI+RQ  I EL  GE D I DLK   K Y +PM KL ++   +   IF  ++ +IP++E  +  L   +  +G  + +G +++ W+   +S
Sbjct:   59 SRNAAPSSTKRRDSKLWSETFDVC-VNQMLTSKEIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQELNQIFGTLDSLIPLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSS 181
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Zebrafish
Match: net1 (neuroepithelial cell transforming 1 [Source:ZFIN;Acc:ZDB-GENE-041121-18])

HSP 1 Score: 149.828 bits (377), Expect = 3.180e-49
Identity = 81/208 (38.94%), Postives = 125/208 (60.10%), Query Frame = 1 
Query:  910 YCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRL 1530
            YC++   +KA L++K++D  + +FLQ C  S FSRKLDLW+FLD PRSRL+KYPLL + IL+ +  +H D   L   +   + +L  ++ K GE  C +Y+ KL++LE  Q    ++    L+  G +   R+    K+H FLF E+L+ T+           + VY  P+P   L+LE++ DG++RM GSFR  FS+   +KN+FR+
Sbjct:  240 YCSNQLAAKALLDQKKQDPRVQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILRHTPPDHPDKGSLEQAISVIQAVLADINMKKGESECQYYIDKLEYLEDKQKDPRIEQCKSLLCHGEL---RNKSGTKLHVFLFTEVLILTRPVTRNDRHC--FQVYRQPIPVQDLVLEDLQDGDVRMGGSFRGAFSNADKAKNIFRV 442

HSP 2 Score: 66.6254 bits (161), Expect = 3.180e-49
Identity = 40/118 (33.90%), Postives = 61/118 (51.69%), Query Frame = 3 
Query:  531 WIETENGRRLGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWVNIGNSLQLNHVNDLV 884
            W ET +  + G   S +EI+RQ  I EL  GE D I DLK   K Y +PM KL ++   +   IF +++  IP++E  +D L      +G +  IG +V+ W+   N+ +    N L 
Sbjct:  130 WSETLDVHQKGT-FSTKEIKRQEAIFELSRGEQDLIEDLKLARKAYHDPMLKLSIMSEEELTAIFGDLDAYIPLHEDLLDQLAKATGTDGTVRQIGKIVVDWLPRLNAYRAYCSNQLA 246
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Zebrafish
Match: net1 (neuroepithelial cell transforming 1 [Source:ZFIN;Acc:ZDB-GENE-041121-18])

HSP 1 Score: 149.828 bits (377), Expect = 4.079e-49
Identity = 81/208 (38.94%), Postives = 125/208 (60.10%), Query Frame = 1 
Query:  910 YCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRL 1530
            YC++   +KA L++K++D  + +FLQ C  S FSRKLDLW+FLD PRSRL+KYPLL + IL+ +  +H D   L   +   + +L  ++ K GE  C +Y+ KL++LE  Q    ++    L+  G +   R+    K+H FLF E+L+ T+           + VY  P+P   L+LE++ DG++RM GSFR  FS+   +KN+FR+
Sbjct:  211 YCSNQLAAKALLDQKKQDPRVQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILRHTPPDHPDKGSLEQAISVIQAVLADINMKKGESECQYYIDKLEYLEDKQKDPRIEQCKSLLCHGEL---RNKSGTKLHVFLFTEVLILTRPVTRNDRHC--FQVYRQPIPVQDLVLEDLQDGDVRMGGSFRGAFSNADKAKNIFRV 413

HSP 2 Score: 65.855 bits (159), Expect = 4.079e-49
Identity = 40/118 (33.90%), Postives = 61/118 (51.69%), Query Frame = 3 
Query:  531 WIETENGRRLGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWVNIGNSLQLNHVNDLV 884
            W ET +  + G   S +EI+RQ  I EL  GE D I DLK   K Y +PM KL ++   +   IF +++  IP++E  +D L      +G +  IG +V+ W+   N+ +    N L 
Sbjct:  101 WSETLDVHQKGT-FSTKEIKRQEAIFELSRGEQDLIEDLKLARKAYHDPMLKLSIMSEEELTAIFGDLDAYIPLHEDLLDQLAKATGTDGTVRQIGKIVVDWLPRLNAYRAYCSNQLA 217
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Zebrafish
Match: arhgef3l (Rho guanine nucleotide exchange factor (GEF) 3, like [Source:ZFIN;Acc:ZDB-GENE-050522-85])

HSP 1 Score: 148.673 bits (374), Expect = 7.470e-49
Identity = 85/215 (39.53%), Postives = 125/215 (58.14%), Query Frame = 1 
Query:  892 LDPIIKYCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEI-RMGSFRSTFSSDRGSKNVFRLT 1533
            L+  I YC +   +KA L++K++DK + +FL+ C  S FSRKLDLWNFLD PRSRL+KYPLL + I KS+  +H D   L   ++  + I+  ++ KTGE  C FY   L + E +Q +  ++    L   G +K   S    K+H FLFE +LV T+   ++     ++ VY  P+P   L LE++ DGE    GSFR  F+ +   KN FR++
Sbjct:  226 LEAYITYCCNQVGAKALLDQKKQDKRVEQFLRLCQESSFSRKLDLWNFLDLPRSRLVKYPLLLKEIQKSTPLDHPDEDALPQAMELIQRIITEVNLKTGEAECQFYRRGLCYAEDSQRVAEIQASRFLYCHGELK---STKGQKLHVFLFELVLVLTRPVAQDREGPVQFQVYRQPMPAAHLHLEDLPDGEPSSSGSFRGAFTGNDKVKNCFRVS 437

HSP 2 Score: 66.2402 bits (160), Expect = 7.470e-49
Identity = 37/118 (31.36%), Postives = 61/118 (51.69%), Query Frame = 3 
Query:  483 GRHDSTSSTHSICKQAWIETENGRRLGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRW 836
             R  ++S       Q W +T +   + + LS +EI+RQ +I+EL  GE   I DL  V K Y EPM KL ++   +   IF  ++ +IP++E  +  LEG +     +  +G  ++ W
Sbjct:  107 SRQKASSFPRRRSSQLWSDTVDN--MSHELSTKEIKRQEVIYELTQGEKQLIEDLSLVKKVYYEPMLKLDIMTESELGQIFGTLDSLIPLHEDLLVRLEGLRGAEKTVQEVGPTMMDW 222
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Zebrafish
Match: arhgef3 (Rho guanine nucleotide exchange factor (GEF) 3 [Source:ZFIN;Acc:ZDB-GENE-050208-773])

HSP 1 Score: 148.288 bits (373), Expect = 3.027e-48
Identity = 86/208 (41.35%), Postives = 127/208 (61.06%), Query Frame = 1 
Query:  910 YCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRL 1530
            YC++   +KA L+ K++D  + +FLQ C  S FSRKLDLWNFLD PRSRL+KYPLL   ILK + +EH D   L + +   + I+  ++ +TGE  C +Y  +L +LE  Q   L+++  +LI  G +K  R V   K+H FLF+++LV T+       E   Y +Y  P+P   L  E++ DGE+R+ GS R  FS++  +KN FR+
Sbjct:  216 YCSNQVAAKALLDHKKQDHRVHDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILKHTPNEHPDRQHLDEAINMIQSIVAGINTQTGESECRYYKERLLYLESGQRDLLIESSRILICHGELKNNRGV---KLHVFLFQDVLVITRAISHN--EQLWYQLYRQPIPVRDLEWEDLQDGEMRVGGSIRGAFSNNERTKNFFRV 418

HSP 2 Score: 64.6994 bits (156), Expect = 3.027e-48
Identity = 34/94 (36.17%), Postives = 55/94 (58.51%), Query Frame = 3 
Query:  558 LGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWV 839
            LG+ LS +EI+RQ  I EL  GE D I DLK   K Y +PM KL ++   +   IF  ++ +IP++E  +  L   ++ +G  D +G +++ W+
Sbjct:  114 LGHMLSSKEIKRQEAIFELSQGEQDLIEDLKLAKKAYHDPMLKLCIMTEHELNQIFGTLDSLIPLHEDLLSRLRDVRNPDGSTDHMGHILVHWL 207
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Zebrafish
Match: net1 (neuroepithelial cell transforming 1 [Source:ZFIN;Acc:ZDB-GENE-041121-18])

HSP 1 Score: 142.124 bits (357), Expect = 8.131e-43
Identity = 83/213 (38.97%), Postives = 126/213 (59.15%), Query Frame = 1 
Query:  910 YCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFS-SDRGSKNVFRLTLLS 1542
            YC++   +KA L++K++D  + +FLQ C  S FSRKLDLW+FLD PRSRL+KYPLL + IL+ +  +H D   L   +   + +L  ++ K GE  C +Y+ KL++LE  Q    ++    L+  G +   R+    K+H FLF E+L+ T+           + VY  P+P   L+LE++ DG++RM GSFR  FS +D+G     +LT LS
Sbjct:   90 YCSNQLAAKALLDQKKQDPRVQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILRHTPPDHPDKGSLEQAISVIQAVLADINMKKGESECQYYIDKLEYLEDKQKDPRIEQCKSLLCHGEL---RNKSGTKLHVFLFTEVLILTRPVTRNDRHC--FQVYRQPIPVQDLVLEDLQDGDVRMGGSFRGAFSNADKG-----KLTPLS 292

HSP 2 Score: 52.7582 bits (125), Expect = 8.131e-43
Identity = 31/94 (32.98%), Postives = 48/94 (51.06%), Query Frame = 3 
Query:  603 IHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWVNIGNSLQLNHVNDLV 884
            I EL  GE D I DLK   K Y +PM KL ++   +   IF +++  IP++E  +D L      +G +  IG +V+ W+   N+ +    N L 
Sbjct:    3 IFELSRGEQDLIEDLKLARKAYHDPMLKLSIMSEEELTAIFGDLDAYIPLHEDLLDQLAKATGTDGTVRQIGKIVVDWLPRLNAYRAYCSNQLA 96
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Xenopus
Match: arhgef3.2 (Rho guanine nucleotide exchange factor 3 [Source:NCBI gene;Acc:100486292])

HSP 1 Score: 147.517 bits (371), Expect = 1.276e-47
Identity = 84/208 (40.38%), Postives = 127/208 (61.06%), Query Frame = 1 
Query:  910 YCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRL 1530
            YC++   +KA L+ K++D  + +FLQ C  S FSRKLDLWNFLD PRSRL+KY LL + IL+ + ++H D   L + +   + I+  ++ KTGE  C++Y  +L +L++ Q   L+ N   L   G +K  R   F   H FLF+++LV T+   +   E+  Y VY  P+P   LIL+++ DGE+R+ GS R  FS++   KN FR+
Sbjct:  214 YCSNQVAAKALLDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYHLLLKEILRHTPNDHQDQQHLEEAINIVQGIVADINVKTGESECHYYKERLIYLDECQKDPLIDNSRALCCHGELKNNRGAKF---HVFLFQDVLVITRTITQN--EALYYQVYRQPIPVKDLILDDLQDGEVRLAGSLRGAFSNNERIKNFFRV 416

HSP 2 Score: 63.929 bits (154), Expect = 1.276e-47
Identity = 33/95 (34.74%), Postives = 54/95 (56.84%), Query Frame = 3 
Query:  570 LSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWVNIGNS 854
            L+ QEI+RQ  I EL  GE D I DLK   K Y +PM KL ++   +   IF  ++ +IP++E  +  L   +  +G ++ +G +++ W+   NS
Sbjct:  116 LTSQEIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQELTQIFGTLDSLIPLHEDLLRRLREVRKPDGSMENVGHILVGWLPCLNS 210
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Xenopus
Match: arhgef3.2 (Rho guanine nucleotide exchange factor 3 [Source:NCBI gene;Acc:100486292])

HSP 1 Score: 147.132 bits (370), Expect = 1.319e-47
Identity = 84/208 (40.38%), Postives = 127/208 (61.06%), Query Frame = 1 
Query:  910 YCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRL 1530
            YC++   +KA L+ K++D  + +FLQ C  S FSRKLDLWNFLD PRSRL+KY LL + IL+ + ++H D   L + +   + I+  ++ KTGE  C++Y  +L +L++ Q   L+ N   L   G +K  R   F   H FLF+++LV T+   +   E+  Y VY  P+P   LIL+++ DGE+R+ GS R  FS++   KN FR+
Sbjct:  206 YCSNQVAAKALLDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYHLLLKEILRHTPNDHQDQQHLEEAINIVQGIVADINVKTGESECHYYKERLIYLDECQKDPLIDNSRALCCHGELKNNRGAKF---HVFLFQDVLVITRTITQN--EALYYQVYRQPIPVKDLILDDLQDGEVRLAGSLRGAFSNNERIKNFFRV 408

HSP 2 Score: 64.3142 bits (155), Expect = 1.319e-47
Identity = 33/95 (34.74%), Postives = 54/95 (56.84%), Query Frame = 3 
Query:  570 LSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWVNIGNS 854
            L+ QEI+RQ  I EL  GE D I DLK   K Y +PM KL ++   +   IF  ++ +IP++E  +  L   +  +G ++ +G +++ W+   NS
Sbjct:  108 LTSQEIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQELTQIFGTLDSLIPLHEDLLRRLREVRKPDGSMENVGHILVGWLPCLNS 202
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Xenopus
Match: arhgef3.2 (Rho guanine nucleotide exchange factor 3 [Source:NCBI gene;Acc:100486292])

HSP 1 Score: 147.517 bits (371), Expect = 1.351e-47
Identity = 84/208 (40.38%), Postives = 127/208 (61.06%), Query Frame = 1 
Query:  910 YCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRL 1530
            YC++   +KA L+ K++D  + +FLQ C  S FSRKLDLWNFLD PRSRL+KY LL + IL+ + ++H D   L + +   + I+  ++ KTGE  C++Y  +L +L++ Q   L+ N   L   G +K  R   F   H FLF+++LV T+   +   E+  Y VY  P+P   LIL+++ DGE+R+ GS R  FS++   KN FR+
Sbjct:  254 YCSNQVAAKALLDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYHLLLKEILRHTPNDHQDQQHLEEAINIVQGIVADINVKTGESECHYYKERLIYLDECQKDPLIDNSRALCCHGELKNNRGAKF---HVFLFQDVLVITRTITQN--EALYYQVYRQPIPVKDLILDDLQDGEVRLAGSLRGAFSNNERIKNFFRV 456

HSP 2 Score: 63.929 bits (154), Expect = 1.351e-47
Identity = 33/95 (34.74%), Postives = 54/95 (56.84%), Query Frame = 3 
Query:  570 LSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWVNIGNS 854
            L+ QEI+RQ  I EL  GE D I DLK   K Y +PM KL ++   +   IF  ++ +IP++E  +  L   +  +G ++ +G +++ W+   NS
Sbjct:  156 LTSQEIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQELTQIFGTLDSLIPLHEDLLRRLREVRKPDGSMENVGHILVGWLPCLNS 250
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Xenopus
Match: arhgef3.2 (Rho guanine nucleotide exchange factor 3 [Source:NCBI gene;Acc:100486292])

HSP 1 Score: 147.132 bits (370), Expect = 1.622e-47
Identity = 84/208 (40.38%), Postives = 127/208 (61.06%), Query Frame = 1 
Query:  910 YCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRL 1530
            YC++   +KA L+ K++D  + +FLQ C  S FSRKLDLWNFLD PRSRL+KY LL + IL+ + ++H D   L + +   + I+  ++ KTGE  C++Y  +L +L++ Q   L+ N   L   G +K  R   F   H FLF+++LV T+   +   E+  Y VY  P+P   LIL+++ DGE+R+ GS R  FS++   KN FR+
Sbjct:  217 YCSNQVAAKALLDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYHLLLKEILRHTPNDHQDQQHLEEAINIVQGIVADINVKTGESECHYYKERLIYLDECQKDPLIDNSRALCCHGELKNNRGAKF---HVFLFQDVLVITRTITQN--EALYYQVYRQPIPVKDLILDDLQDGEVRLAGSLRGAFSNNERIKNFFRV 419

HSP 2 Score: 63.929 bits (154), Expect = 1.622e-47
Identity = 33/95 (34.74%), Postives = 54/95 (56.84%), Query Frame = 3 
Query:  570 LSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWVNIGNS 854
            L+ QEI+RQ  I EL  GE D I DLK   K Y +PM KL ++   +   IF  ++ +IP++E  +  L   +  +G ++ +G +++ W+   NS
Sbjct:  119 LTSQEIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQELTQIFGTLDSLIPLHEDLLRRLREVRKPDGSMENVGHILVGWLPCLNS 213
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Xenopus
Match: arhgef3.2 (Rho guanine nucleotide exchange factor 3 [Source:NCBI gene;Acc:100486292])

HSP 1 Score: 146.747 bits (369), Expect = 1.622e-47
Identity = 84/208 (40.38%), Postives = 127/208 (61.06%), Query Frame = 1 
Query:  910 YCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRL 1530
            YC++   +KA L+ K++D  + +FLQ C  S FSRKLDLWNFLD PRSRL+KY LL + IL+ + ++H D   L + +   + I+  ++ KTGE  C++Y  +L +L++ Q   L+ N   L   G +K  R   F   H FLF+++LV T+   +   E+  Y VY  P+P   LIL+++ DGE+R+ GS R  FS++   KN FR+
Sbjct:  215 YCSNQVAAKALLDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYHLLLKEILRHTPNDHQDQQHLEEAINIVQGIVADINVKTGESECHYYKERLIYLDECQKDPLIDNSRALCCHGELKNNRGAKF---HVFLFQDVLVITRTITQN--EALYYQVYRQPIPVKDLILDDLQDGEVRLAGSLRGAFSNNERIKNFFRV 417

HSP 2 Score: 64.3142 bits (155), Expect = 1.622e-47
Identity = 33/95 (34.74%), Postives = 54/95 (56.84%), Query Frame = 3 
Query:  570 LSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWVNIGNS 854
            L+ QEI+RQ  I EL  GE D I DLK   K Y +PM KL ++   +   IF  ++ +IP++E  +  L   +  +G ++ +G +++ W+   NS
Sbjct:  117 LTSQEIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQELTQIFGTLDSLIPLHEDLLRRLREVRKPDGSMENVGHILVGWLPCLNS 211
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Mouse
Match: Net1 (neuroepithelial cell transforming gene 1 [Source:MGI Symbol;Acc:MGI:1927138])

HSP 1 Score: 152.525 bits (384), Expect = 2.518e-49
Identity = 83/208 (39.90%), Postives = 131/208 (62.98%), Query Frame = 1 
Query:  910 YCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRL 1530
            YC++   +KA L++K++D  + +FLQ C  S FSRKLDLW+FLD PRSRL+KYPLL + IL+ +  +H D   L + +   + +L  ++ K GE  C +Y+ KL++L++ Q    ++   VL+  G +K   +   HK++ FLF++ILV T+       E   Y VY  P+P  +L+LE++ DG++RM GSFR  F +   +KN+FR+
Sbjct:  266 YCSNQLAAKALLDQKKQDPRVQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILRHTPKDHRDVQLLEEAILIIQGVLSDINLKKGESECQYYINKLEYLDEKQKDPRIEASKVLLCHGELK---NKSGHKLYIFLFQDILVLTRPVTRN--ERHLYQVYRQPIPVQELVLEDLQDGDVRMGGSFRGAFGNSDKAKNIFRV 468

HSP 2 Score: 63.929 bits (154), Expect = 2.518e-49
Identity = 39/142 (27.46%), Postives = 71/142 (50.00%), Query Frame = 3 
Query:  453 YGITTAAIII-GRHDSTSSTHSICKQAWIETENGRR------------LGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWV 839
            +G T  +  + G H S +S      ++ + T   RR            +  +L+ +EI+RQ  I+EL  GE D I DLK   K Y +PM KL ++   +  +IF +++  IP++E  +  +      +G ++ IG +++ W+
Sbjct:  116 FGQTIQSFTLRGDHRSPASAQKSFSRSTVPTPTKRRSSALWSEMLDINMKESLTTREIKRQEAIYELSRGEQDLIEDLKLARKAYHDPMLKLSIMSEEELTHIFGDLDAYIPLHEDLLARIGEATKPDGTVEQIGHILVNWL 257
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Mouse
Match: Net1 (neuroepithelial cell transforming gene 1 [Source:MGI Symbol;Acc:MGI:1927138])

HSP 1 Score: 152.91 bits (385), Expect = 2.925e-49
Identity = 96/278 (34.53%), Postives = 149/278 (53.60%), Query Frame = 1 
Query:  910 YCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRLTLLSNFIPEIEFDDHNDYNERALEDTFASNDKYEQSPYDGRLLKNSQTILQTSQLEEKQLWLNTLRKVVA 1740
            YC++   +KA L++K++D  + +FLQ C  S FSRKLDLW+FLD PRSRL+KYPLL + IL+ +  +H D   L + +   + +L  ++ K GE  C +Y+ KL++L++ Q    ++   VL+  G +K   +   HK++ FLF++ILV T+       E   Y VY  P+P  +L+LE++ DG++RM GSFR  F +   +KN+FR+                                  Q P  G    +S T LQ + +  KQ W N +R  +A
Sbjct:  212 YCSNQLAAKALLDQKKQDPRVQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILRHTPKDHRDVQLLEEAILIIQGVLSDINLKKGESECQYYINKLEYLDEKQKDPRIEASKVLLCHGELK---NKSGHKLYIFLFQDILVLTRPVTRN--ERHLYQVYRQPIPVQELVLEDLQDGDVRMGGSFRGAFGNSDKAKNIFRVRF--------------------------------QDPSPG----HSHT-LQANDVFHKQQWFNCIRAAIA 447

HSP 2 Score: 63.5438 bits (153), Expect = 2.925e-49
Identity = 39/142 (27.46%), Postives = 71/142 (50.00%), Query Frame = 3 
Query:  453 YGITTAAIII-GRHDSTSSTHSICKQAWIETENGRR------------LGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWV 839
            +G T  +  + G H S +S      ++ + T   RR            +  +L+ +EI+RQ  I+EL  GE D I DLK   K Y +PM KL ++   +  +IF +++  IP++E  +  +      +G ++ IG +++ W+
Sbjct:   62 FGQTIQSFTLRGDHRSPASAQKSFSRSTVPTPTKRRSSALWSEMLDINMKESLTTREIKRQEAIYELSRGEQDLIEDLKLARKAYHDPMLKLSIMSEEELTHIFGDLDAYIPLHEDLLARIGEATKPDGTVEQIGHILVNWL 203
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Mouse
Match: Arhgef3 (Rho guanine nucleotide exchange factor (GEF) 3 [Source:MGI Symbol;Acc:MGI:1918954])

HSP 1 Score: 153.68 bits (387), Expect = 4.846e-49
Identity = 86/209 (41.15%), Postives = 128/209 (61.24%), Query Frame = 1 
Query:  910 YCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRLT 1533
            YC++   +KA L+ K++D  + +FLQ C  S FSRKLDLWNFLD PRSRL+KYPLL   IL+ + +++ D   L + +   + I+  ++ KTGE  C +Y  +L +LE+ Q  +L+ +  VL   G +K  R V   K+H FLF+E+LV T+       E   Y +Y  P+P   L LE++ DGE+R+ GS R  FS++   KN FR++
Sbjct:  240 YCSNQVAAKALLDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHTPNDNPDQQHLEEAINIIQGIVAEINTKTGESECRYYKERLLYLEEGQKDSLIDSSRVLCCHGELKNNRGV---KLHVFLFQEVLVITRAVTHN--EQLCYQLYRQPIPVKDLTLEDLQDGEVRLGGSLRGAFSNNERVKNFFRVS 443

HSP 2 Score: 62.003 bits (149), Expect = 4.846e-49
Identity = 38/124 (30.65%), Postives = 66/124 (53.23%), Query Frame = 3 
Query:  483 GRHDSTSSTHSICKQAWIETENGRRLGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWVNIGNS 854
             R+ ++SST     + W ET +   +   L+ +EI+RQ  I EL  GE D I DLK   K Y +PM KL ++   +   IF  ++ +IP++E  +  L   +  +G  + +G +++ W+   +S
Sbjct:  114 SRNATSSSTKRRDSKLWSETFDVC-VNQVLTAKEIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQELNQIFGTLDSLIPLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSS 236
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Mouse
Match: Arhgef3 (Rho guanine nucleotide exchange factor (GEF) 3 [Source:MGI Symbol;Acc:MGI:1918954])

HSP 1 Score: 153.68 bits (387), Expect = 6.062e-49
Identity = 86/209 (41.15%), Postives = 128/209 (61.24%), Query Frame = 1 
Query:  910 YCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRLT 1533
            YC++   +KA L+ K++D  + +FLQ C  S FSRKLDLWNFLD PRSRL+KYPLL   IL+ + +++ D   L + +   + I+  ++ KTGE  C +Y  +L +LE+ Q  +L+ +  VL   G +K  R V   K+H FLF+E+LV T+       E   Y +Y  P+P   L LE++ DGE+R+ GS R  FS++   KN FR++
Sbjct:  220 YCSNQVAAKALLDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHTPNDNPDQQHLEEAINIIQGIVAEINTKTGESECRYYKERLLYLEEGQKDSLIDSSRVLCCHGELKNNRGV---KLHVFLFQEVLVITRAVTHN--EQLCYQLYRQPIPVKDLTLEDLQDGEVRLGGSLRGAFSNNERVKNFFRVS 423

HSP 2 Score: 61.6178 bits (148), Expect = 6.062e-49
Identity = 38/124 (30.65%), Postives = 66/124 (53.23%), Query Frame = 3 
Query:  483 GRHDSTSSTHSICKQAWIETENGRRLGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWVNIGNS 854
             R+ ++SST     + W ET +   +   L+ +EI+RQ  I EL  GE D I DLK   K Y +PM KL ++   +   IF  ++ +IP++E  +  L   +  +G  + +G +++ W+   +S
Sbjct:   94 SRNATSSSTKRRDSKLWSETFDVC-VNQVLTAKEIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQELNQIFGTLDSLIPLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSS 216
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Mouse
Match: Arhgef3 (Rho guanine nucleotide exchange factor (GEF) 3 [Source:MGI Symbol;Acc:MGI:1918954])

HSP 1 Score: 153.295 bits (386), Expect = 8.034e-49
Identity = 86/209 (41.15%), Postives = 128/209 (61.24%), Query Frame = 1 
Query:  910 YCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRLT 1533
            YC++   +KA L+ K++D  + +FLQ C  S FSRKLDLWNFLD PRSRL+KYPLL   IL+ + +++ D   L + +   + I+  ++ KTGE  C +Y  +L +LE+ Q  +L+ +  VL   G +K  R V   K+H FLF+E+LV T+       E   Y +Y  P+P   L LE++ DGE+R+ GS R  FS++   KN FR++
Sbjct:  213 YCSNQVAAKALLDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHTPNDNPDQQHLEEAINIIQGIVAEINTKTGESECRYYKERLLYLEEGQKDSLIDSSRVLCCHGELKNNRGV---KLHVFLFQEVLVITRAVTHN--EQLCYQLYRQPIPVKDLTLEDLQDGEVRLGGSLRGAFSNNERVKNFFRVS 416

HSP 2 Score: 61.6178 bits (148), Expect = 8.034e-49
Identity = 38/124 (30.65%), Postives = 66/124 (53.23%), Query Frame = 3 
Query:  483 GRHDSTSSTHSICKQAWIETENGRRLGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWVNIGNS 854
             R+ ++SST     + W ET +   +   L+ +EI+RQ  I EL  GE D I DLK   K Y +PM KL ++   +   IF  ++ +IP++E  +  L   +  +G  + +G +++ W+   +S
Sbjct:   87 SRNATSSSTKRRDSKLWSETFDVC-VNQVLTAKEIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQELNQIFGTLDSLIPLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSS 209
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. UniProt/SwissProt
Match: sp|Q7Z628|ARHG8_HUMAN (Neuroepithelial cell-transforming gene 1 protein OS=Homo sapiens OX=9606 GN=NET1 PE=1 SV=1)

HSP 1 Score: 157.918 bits (398), Expect = 2.987e-50
Identity = 101/278 (36.33%), Postives = 149/278 (53.60%), Query Frame = 1 
Query:  910 YCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRLTLLSNFIPEIEFDDHNDYNERALEDTFASNDKYEQSPYDGRLLKNSQTILQTSQLEEKQLWLNTLRKVVA 1740
            YC++   +KA L++K++D  + +FLQ C  S FSRKLDLW+FLD PRSRL+KYPLL + ILK +  EH D   L D +   + +L  ++ K GE  C +Y+ KL++L++ Q    ++   VL+  G +   RS   HK++ FLF++ILV T+       E   Y VY  P+P  +L+LE++ DG++RM GSFR  FS+   +KN+FR          I F D +     A   T  +ND +                        KQ W N +R  +A
Sbjct:  266 YCSNQLAAKALLDQKKQDPRVQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILKHTPKEHPDVQLLEDAILIIQGVLSDINLKKGESECQYYIDKLEYLDEKQRDPRIEASKVLLCHGEL---RSKSGHKLYIFLFQDILVLTRPVTRN--ERHSYQVYRQPIPVQELVLEDLQDGDVRMGGSFRGAFSNSEKAKNIFR----------IRFHDPSP----AQSHTLQANDVF-----------------------HKQQWFNCIRAAIA 501

HSP 2 Score: 64.3142 bits (155), Expect = 2.987e-50
Identity = 41/157 (26.11%), Postives = 75/157 (47.77%), Query Frame = 3 
Query:  453 YGITTAAIII-GRHDSTSSTHSICKQAWIETENGRR------------LGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWVNIGNSLQLNHVNDLV 884
            +G T  +  + G H S +S      ++ + T   RR            +  +L+ +EI RQ  I+E+  GE D I DLK   K Y +PM KL ++   +  +IF +++  IP++E  +  +      +G ++ IG +++ W+   N+ +    N L 
Sbjct:  116 FGQTIQSFTLRGDHRSPASAQKFSSRSTVPTPAKRRSSALWSEMLDITMKESLTTREIRRQEAIYEMSRGEQDLIEDLKLARKAYHDPMLKLSIMSEEELTHIFGDLDSYIPLHEDLLTRIGEATKPDGTVEQIGHILVSWLPRLNAYRGYCSNQLA 272
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. UniProt/SwissProt
Match: sp|Q9Z206|ARHG8_MOUSE (Neuroepithelial cell-transforming gene 1 protein OS=Mus musculus OX=10090 GN=Net1 PE=1 SV=2)

HSP 1 Score: 152.525 bits (384), Expect = 1.525e-48
Identity = 83/208 (39.90%), Postives = 131/208 (62.98%), Query Frame = 1 
Query:  910 YCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRL 1530
            YC++   +KA L++K++D  + +FLQ C  S FSRKLDLW+FLD PRSRL+KYPLL + IL+ +  +H D   L + +   + +L  ++ K GE  C +Y+ KL++L++ Q    ++   VL+  G +K   +   HK++ FLF++ILV T+       E   Y VY  P+P  +L+LE++ DG++RM GSFR  F +   +KN+FR+
Sbjct:  266 YCSNQLAAKALLDQKKQDPRVQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILRHTPKDHRDVQLLEEAILIIQGVLSDINLKKGESECQYYINKLEYLDEKQKDPRIEASKVLLCHGELK---NKSGHKLYIFLFQDILVLTRPVTRN--ERHLYQVYRQPIPVQELVLEDLQDGDVRMGGSFRGAFGNSDKAKNIFRV 468

HSP 2 Score: 63.929 bits (154), Expect = 1.525e-48
Identity = 39/142 (27.46%), Postives = 71/142 (50.00%), Query Frame = 3 
Query:  453 YGITTAAIII-GRHDSTSSTHSICKQAWIETENGRR------------LGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWV 839
            +G T  +  + G H S +S      ++ + T   RR            +  +L+ +EI+RQ  I+EL  GE D I DLK   K Y +PM KL ++   +  +IF +++  IP++E  +  +      +G ++ IG +++ W+
Sbjct:  116 FGQTIQSFTLRGDHRSPASAQKSFSRSTVPTPTKRRSSALWSEMLDINMKESLTTREIKRQEAIYELSRGEQDLIEDLKLARKAYHDPMLKLSIMSEEELTHIFGDLDAYIPLHEDLLARIGEATKPDGTVEQIGHILVNWL 257
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. UniProt/SwissProt
Match: sp|Q9N0A8|ARHG3_MACFA (Rho guanine nucleotide exchange factor 3 OS=Macaca fascicularis OX=9541 GN=ARHGEF3 PE=2 SV=1)

HSP 1 Score: 154.066 bits (388), Expect = 3.828e-48
Identity = 86/209 (41.15%), Postives = 129/209 (61.72%), Query Frame = 1 
Query:  910 YCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRLT 1533
            YC++   +KA L+ K++D  + +FLQ C  S FSRKLDLWNFLD PRSRL+KYPLL   IL+ + +++ D   L + +   + I+  ++ KTGE  C +Y  +L +LE+ Q  +L+ +  VL   G +K  R V   K+H FLF+E+LV T+       E   Y +Y  P+P   L+LE++ DGE+R+ GS R  FS++   KN FR++
Sbjct:  214 YCSNQVAAKALLDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHTPNDNPDQQHLEEAINIIQGIVAEINTKTGESECRYYKERLLYLEEGQKDSLIDSSRVLCCHGELKNNRGV---KLHVFLFQEVLVITRAVTHN--EQLCYQLYRQPIPVKDLLLEDLQDGEVRLGGSLRGAFSNNERIKNFFRVS 417

HSP 2 Score: 61.2326 bits (147), Expect = 3.828e-48
Identity = 38/124 (30.65%), Postives = 65/124 (52.42%), Query Frame = 3 
Query:  483 GRHDSTSSTHSICKQAWIETENGRRLGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWVNIGNS 854
             R+ + SST     + W ET +   +   L+ +EI+RQ  I EL  GE D I DLK   K Y +PM KL ++   +   IF  ++ +IP++E  +  L   +  +G  + +G +++ W+   +S
Sbjct:   88 SRNAAPSSTKRRDSKLWSETFDVC-VNQMLTSKEIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQELNQIFGTLDSLIPLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSS 210
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. UniProt/SwissProt
Match: sp|Q9NR81|ARHG3_HUMAN (Rho guanine nucleotide exchange factor 3 OS=Homo sapiens OX=9606 GN=ARHGEF3 PE=1 SV=1)

HSP 1 Score: 154.066 bits (388), Expect = 3.957e-48
Identity = 86/209 (41.15%), Postives = 129/209 (61.72%), Query Frame = 1 
Query:  910 YCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRLT 1533
            YC++   +KA L+ K++D  + +FLQ C  S FSRKLDLWNFLD PRSRL+KYPLL   IL+ + +++ D   L + +   + I+  ++ KTGE  C +Y  +L +LE+ Q  +L+ +  VL   G +K  R V   K+H FLF+E+LV T+       E   Y +Y  P+P   L+LE++ DGE+R+ GS R  FS++   KN FR++
Sbjct:  214 YCSNQVAAKALLDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHTPNDNPDQQHLEEAINIIQGIVAEINTKTGESECRYYKERLLYLEEGQKDSLIDSSRVLCCHGELKNNRGV---KLHVFLFQEVLVITRAVTHN--EQLCYQLYRQPIPVKDLLLEDLQDGEVRLGGSLRGAFSNNERIKNFFRVS 417

HSP 2 Score: 61.2326 bits (147), Expect = 3.957e-48
Identity = 38/124 (30.65%), Postives = 65/124 (52.42%), Query Frame = 3 
Query:  483 GRHDSTSSTHSICKQAWIETENGRRLGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWVNIGNS 854
             R+ + SST     + W ET +   +   L+ +EI+RQ  I EL  GE D I DLK   K Y +PM KL ++   +   IF  ++ +IP++E  +  L   +  +G  + +G +++ W+   +S
Sbjct:   88 SRNAAPSSTKRRDSKLWSETFDVC-VNQMLTSKEIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQELNQIFGTLDSLIPLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSS 210
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. UniProt/SwissProt
Match: sp|Q5ZLX4|ARHG3_CHICK (Rho guanine nucleotide exchange factor 3 OS=Gallus gallus OX=9031 GN=Arhgef3 PE=2 SV=1)

HSP 1 Score: 154.066 bits (388), Expect = 4.517e-48
Identity = 88/209 (42.11%), Postives = 128/209 (61.24%), Query Frame = 1 
Query:  910 YCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRLT 1533
            YC++   +KA L+ K++D  + +FLQ C  S FSRKLDLWNFLD PRSRL+KYPLL   IL+ + ++H D   L + +   + I+  ++ KTGE  C +Y  +L +LE  Q  +L+ N  VL   G +K  R V   K+H FLF+E+LV T+       E   Y +Y  P+P   L+LE++ DGE+R+ GS R  FS++   KN FR++
Sbjct:  214 YCSNQVAAKALLDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHTPNDHPDQQHLEEAINIIQGIVAEINIKTGESECQYYKERLIYLEGGQRDSLIDNSRVLCCHGELKNNRGV---KLHVFLFQEVLVITRAITHN--EQLCYQLYRQPIPVMDLVLEDLQDGEVRLGGSIRGAFSNNERIKNFFRVS 417

HSP 2 Score: 60.8474 bits (146), Expect = 4.517e-48
Identity = 32/95 (33.68%), Postives = 54/95 (56.84%), Query Frame = 3 
Query:  570 LSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWVNIGNS 854
            L+ +EI+RQ  I EL  GE D I DLK   K Y +PM KL ++   +   IF  ++ +IP++E  +  L+  +  +G  + +G +++ W+   NS
Sbjct:  116 LTSKEIKRQEAIFELSKGEEDLIEDLKLAKKAYHDPMLKLSIMTEQELNQIFGTLDSLIPLHEDLLRRLQEVRKSDGSTEHVGHILVGWLPCLNS 210
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. TrEMBL
Match: A0A402FXK4 (Uncharacterized protein OS=Paroedura picta OX=143630 GN=parPi_0024851 PE=4 SV=1)

HSP 1 Score: 156.762 bits (395), Expect = 1.016e-49
Identity = 84/208 (40.38%), Postives = 133/208 (63.94%), Query Frame = 1 
Query:  910 YCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRL 1530
            YC++   +KA L++K++D+ + +FLQ C  S FSRKLDLW+FLD PRSRL+KYPLL + IL+ + ++H D   L   +   + +L  ++ K GE  C +Y+ KL++L++ Q    +++  VL+  G +K   + + HK++ FLF+EILV T+       E   Y VY  PLP   L+LE++ DG+++M GSFR  F +   +KN+FR+
Sbjct:  212 YCSNQLAAKALLDQKKQDRRVQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILRHTPNDHPDVQILEKAISIIQGVLSDINLKKGESECQYYIDKLEYLDEKQKDPRIESSKVLLCHGELK---NKNGHKLYVFLFQEILVLTRPVTRN--ERHSYQVYRQPLPVQDLVLEDLQDGDVKMGGSFRGAFGNSDKAKNIFRV 414

HSP 2 Score: 71.633 bits (174), Expect = 1.016e-49
Identity = 43/146 (29.45%), Postives = 70/146 (47.95%), Query Frame = 3 
Query:  483 GRHDSTSSTHSICKQAWIETENGRR------------LGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWVNIGNSLQLNHVNDLV 884
            G   S S     C ++   T   RR            +   LS +EI+RQ  I+EL  GE D I DLK   K Y +PM KL ++   +  +IF +++  IP++E F+  L      +G ++ IG ++++W+   N+ +    N L 
Sbjct:   73 GDSKSPSCAQKPCSRSAAPTPPKRRNSVLWSETLDVNMKETLSAKEIKRQEAIYELSRGEQDLIEDLKLARKAYHDPMLKLSIMSEEELTHIFGDLDSYIPLHEDFLARLAEATRPDGTVEKIGPILVKWLPGLNAYKAYCSNQLA 218
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. TrEMBL
Match: A0A3B3ZJB6 (Neuroepithelial cell transforming 1 OS=Periophthalmus magnuspinnatus OX=409849 PE=4 SV=1)

HSP 1 Score: 157.147 bits (396), Expect = 1.077e-49
Identity = 98/278 (35.25%), Postives = 149/278 (53.60%), Query Frame = 1 
Query:  910 YCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRLTLLSNFIPEIEFDDHNDYNERALEDTFASNDKYEQSPYDGRLLKNSQTILQTSQLEEKQLWLNTLRKVVA 1740
            YC++   +KA L++K++D  + +FLQ C  S FSRKLDLW+FLD PRSRL+KYPLL ++IL+ +  EH D++ L   +   + +L  +D K GE  C +Y+ KL++L++ Q  + ++    L+  G +   RS    K+H FLF E+LV T+       E   + VY  P+P   L+LE++ DG++RM GSFR  FS+   +KN+FR+                            S D  +          +S   LQ + +  KQ WLN LR  +A
Sbjct:  210 YCSNQLAAKALLDQKKQDPRVQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKQILRHTPPEHPDTASLEQAISLIQDVLADIDLKKGESECQYYIDKLEYLDERQRDSRIEQCKSLLCHGEL---RSKSGTKLHVFLFTEVLVLTRSVSRN--ERQCFQVYRQPIPVQDLVLEDLQDGDVRMGGSFRGAFSNADRAKNIFRVR---------------------------SQDPTQ---------THSSHTLQVNDIFHKQQWLNCLRSAIA 446

HSP 2 Score: 70.8626 bits (172), Expect = 1.077e-49
Identity = 44/146 (30.14%), Postives = 67/146 (45.89%), Query Frame = 3 
Query:  453 YGITTAAIIIGRHDSTSSTHSICKQAWIETENGRR------------LGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWVNIGNS 854
            +G T  A   G   S ++ H  C +A   T   RR                +S +EI+RQ  I EL  GE D I DL+   K Y +PM KL ++   +   IF N++  IP++E  +  L      +G +  IG +V+ W+   N+
Sbjct:   61 FGQTIQASFRGDGKSPAAPHKTCSKATAPTPPKRRNSILWSENLDLHQKGTMSVKEIKRQEAIFELSRGEHDLIEDLQLARKAYHDPMLKLSIMSEEELTQIFGNLDAFIPLHEDLLQQLSKATAEDGTVGQIGQIVVSWLPRLNA 206
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. TrEMBL
Match: A0A3B3TZ94 (Neuroepithelial cell transforming 1 OS=Poecilia latipinna OX=48699 PE=4 SV=1)

HSP 1 Score: 150.214 bits (378), Expect = 2.018e-49
Identity = 83/208 (39.90%), Postives = 129/208 (62.02%), Query Frame = 1 
Query:  910 YCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRL 1530
            YC++   +KA L++K++D+ + +FLQ C  S FSRKLDLW+FLD PRSRL+KYPLL + IL+ +  +H D+  L + +   + +L  ++ K GE  C +Y+ KL++L+  Q    ++    L+  G +   R+    K+H FLF EILV T+       E   + VY  P+P   L+LE++ DG++RM GSFR  FS+   +KN+FR+
Sbjct:  291 YCSNQLAAKALLDQKKQDRRVQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILRRTPPDHPDAGLLEEAITIIQGVLSDINMKKGESECQYYIEKLEYLDDRQRDPRIEQCKSLLCHGEL---RNKSGTKLHVFLFTEILVLTRPVTRN--ERQCFQVYRQPIPVQDLVLEDLQDGDVRMGGSFRGAFSNSEKAKNIFRV 493

HSP 2 Score: 77.0258 bits (188), Expect = 2.018e-49
Identity = 50/157 (31.85%), Postives = 76/157 (48.41%), Query Frame = 3 
Query:  453 YGITTAAIIIGRHDSTSSTHSICKQA-------------WIETENGRRLGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWVNIGNSLQLNHVNDLV 884
            +G T  A   G   S++  H  C +A             W ET + R+ G  LS QEI+RQ +I EL  GE D I DL+   K Y +PM KL ++   +  +IF N++  IP++E  +  L      +G +  IG +V+ W+   N+ +    N L 
Sbjct:  142 FGQTLQASFRGDGKSSAVPHKPCSKATAPTPPKRRNSTLWSETLDVRQKGT-LSTQEIKRQEVIFELARGEQDLIEDLQLARKAYHDPMLKLSIMSEEELTHIFGNLDDYIPLHEDLLAQLSKATGSDGTVGQIGQIVISWLPRLNAYKEYCSNQLA 297
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. TrEMBL
Match: A0A3B3VEB8 (Neuroepithelial cell transforming 1 OS=Poecilia latipinna OX=48699 PE=4 SV=1)

HSP 1 Score: 150.599 bits (379), Expect = 3.057e-49
Identity = 83/209 (39.71%), Postives = 130/209 (62.20%), Query Frame = 1 
Query:  907 KYCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRL 1530
            +YC++   +KA L++K++D+ + +FLQ C  S FSRKLDLW+FLD PRSRL+KYPLL + IL+ +  +H D+  L + +   + +L  ++ K GE  C +Y+ KL++L+  Q    ++    L+  G +   R+    K+H FLF EILV T+       E   + VY  P+P   L+LE++ DG++RM GSFR  FS+   +KN+FR+
Sbjct:  210 EYCSNQLAAKALLDQKKQDRRVQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILRRTPPDHPDAGLLEEAITIIQGVLSDINMKKGESECQYYIEKLEYLDDRQRDPRIEQCKSLLCHGEL---RNKSGTKLHVFLFTEILVLTRPVTRN--ERQCFQVYRQPIPVQDLVLEDLQDGDVRMGGSFRGAFSNSEKAKNIFRV 413

HSP 2 Score: 76.2554 bits (186), Expect = 3.057e-49
Identity = 48/147 (32.65%), Postives = 73/147 (49.66%), Query Frame = 3 
Query:  453 YGITTAAIIIGRHDSTSSTHSICKQA-------------WIETENGRRLGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWVNIGNS 854
            +G T  A   G   S++  H  C +A             W ET + R+ G  LS QEI+RQ +I EL  GE D I DL+   K Y +PM KL ++   +  +IF N++  IP++E  +  L      +G +  IG +V+ W+   N+
Sbjct:   62 FGQTLQASFRGDGKSSAVPHKPCSKATAPTPPKRRNSTLWSETLDVRQKGT-LSTQEIKRQEVIFELARGEQDLIEDLQLARKAYHDPMLKLSIMSEEELTHIFGNLDDYIPLHEDLLAQLSKATGSDGTVGQIGQIVISWLPRLNA 207
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. TrEMBL
Match: A0A3B3WPG8 (Neuroepithelial cell transforming 1 OS=Poecilia mexicana OX=48701 PE=4 SV=1)

HSP 1 Score: 150.214 bits (378), Expect = 3.523e-49
Identity = 83/209 (39.71%), Postives = 130/209 (62.20%), Query Frame = 1 
Query:  907 KYCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRL 1530
            +YC++   +KA L++K++D+ + +FLQ C  S FSRKLDLW+FLD PRSRL+KYPLL + IL+ +  +H D+  L + +   + +L  ++ K GE  C +Y+ KL++L+  Q    ++    L+  G +   R+    K+H FLF EILV T+       E   + VY  P+P   L+LE++ DG++RM GSFR  FS+   +KN+FR+
Sbjct:  210 EYCSNQLAAKALLDQKKQDRRVQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILRRTPPDHPDAGLLEEAITIIQGVLSDINMKKGESECQYYIEKLEYLDDRQRDPRIEQCKSLLCHGEL---RNKSGTKLHVFLFTEILVLTRPVTRN--ERQCFQVYRQPIPVQDLVLEDLQDGDVRMGGSFRGAFSNSEKAKNIFRV 413

HSP 2 Score: 76.2554 bits (186), Expect = 3.523e-49
Identity = 47/142 (33.10%), Postives = 71/142 (50.00%), Query Frame = 3 
Query:  453 YGITTAAIIIGRHDSTSSTHSICKQA-------------WIETENGRRLGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWV 839
            +G T  A   G   S++  H  C +A             W ET + R+ G  LS QEI+RQ +I EL  GE D I DL+   K Y +PM KL ++   +  +IF N++  IP++E  +  L      +G +  IG +V+ W+
Sbjct:   62 FGQTLQASFRGDGKSSAVPHKPCSKATAPTPPKRRNSTLWSETLDVRQKGT-LSTQEIKRQEVIFELARGEQDLIEDLQLARKAYHDPMLKLSIMSEEELTHIFGNLDDYIPLHEDLLAQLSKATGSDGTVGQIGQIVISWL 202
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Cavefish
Match: arhgef3l (rho guanine nucleotide exchange factor 3-like [Source:NCBI gene;Acc:103046634])

HSP 1 Score: 150.984 bits (380), Expect = 7.796e-50
Identity = 82/215 (38.14%), Postives = 130/215 (60.47%), Query Frame = 1 
Query:  892 LDPIIKYCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEI-RMGSFRSTFSSDRGSKNVFRLT 1533
            L+  I YC +   +KA L++K++ + + EFL+ C  S FSRKLDLWNFLD PRSRL+KYPLL + I K++ ++H D   L   ++  + I+  +++KTGE  C FY   L + E+ Q ++ ++    L   G +K   +    K+H FLFE +LV T+   ++   + ++ VY  PLP  +++LE++ DGE    GSFR  F+ +   KN FR++
Sbjct:  247 LEAYITYCCNQVGAKALLDQKKQVRRVEEFLRLCQESSFSRKLDLWNFLDLPRSRLVKYPLLLKEIQKTTPADHPDEETLPQAMELIQNIITEVNQKTGEAECQFYRRGLSYPEEGQRVSEIQASRFLYCHGELK---NTKGQKLHVFLFERVLVLTRPVVQDKDGTVQFQVYRQPLPAAQILLEDLPDGEASSSGSFRGAFTGNDKVKNCFRVS 458

HSP 2 Score: 67.0106 bits (162), Expect = 7.796e-50
Identity = 37/120 (30.83%), Postives = 62/120 (51.67%), Query Frame = 3 
Query:  477 IIGRHDSTSSTHSICKQAWIETENGRRLGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRW 836
            I  R  ++S       Q W +T +   +  ++S +EI+RQ +I+E+  GE   I DL  V K Y EPM KL ++   +   IF  ++ +IP++E F+  LE  +     +  +G  +L W
Sbjct:  126 IRTRQKASSFPRRRSSQLWSDTVDS--MSQDMSAREIKRQEVIYEMTQGERQLIEDLSLVKKVYYEPMLKLDIMTESELGQIFGTLDSLIPLHEDFLARLEKLRGSEKTVGEVGPTLLDW 243
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Cavefish
Match: arhgef3l (rho guanine nucleotide exchange factor 3-like [Source:NCBI gene;Acc:103046634])

HSP 1 Score: 150.984 bits (380), Expect = 8.685e-50
Identity = 82/215 (38.14%), Postives = 130/215 (60.47%), Query Frame = 1 
Query:  892 LDPIIKYCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEI-RMGSFRSTFSSDRGSKNVFRLT 1533
            L+  I YC +   +KA L++K++ + + EFL+ C  S FSRKLDLWNFLD PRSRL+KYPLL + I K++ ++H D   L   ++  + I+  +++KTGE  C FY   L + E+ Q ++ ++    L   G +K   +    K+H FLFE +LV T+   ++   + ++ VY  PLP  +++LE++ DGE    GSFR  F+ +   KN FR++
Sbjct:  226 LEAYITYCCNQVGAKALLDQKKQVRRVEEFLRLCQESSFSRKLDLWNFLDLPRSRLVKYPLLLKEIQKTTPADHPDEETLPQAMELIQNIITEVNQKTGEAECQFYRRGLSYPEEGQRVSEIQASRFLYCHGELK---NTKGQKLHVFLFERVLVLTRPVVQDKDGTVQFQVYRQPLPAAQILLEDLPDGEASSSGSFRGAFTGNDKVKNCFRVS 437

HSP 2 Score: 66.6254 bits (161), Expect = 8.685e-50
Identity = 37/120 (30.83%), Postives = 62/120 (51.67%), Query Frame = 3 
Query:  477 IIGRHDSTSSTHSICKQAWIETENGRRLGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRW 836
            I  R  ++S       Q W +T +   +  ++S +EI+RQ +I+E+  GE   I DL  V K Y EPM KL ++   +   IF  ++ +IP++E F+  LE  +     +  +G  +L W
Sbjct:  105 IRTRQKASSFPRRRSSQLWSDTVDS--MSQDMSAREIKRQEVIYEMTQGERQLIEDLSLVKKVYYEPMLKLDIMTESELGQIFGTLDSLIPLHEDFLARLEKLRGSEKTVGEVGPTLLDW 222
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Cavefish
Match: arhgef3 (Rho guanine nucleotide exchange factor 3 [Source:NCBI gene;Acc:103038887])

HSP 1 Score: 148.288 bits (373), Expect = 7.859e-49
Identity = 88/219 (40.18%), Postives = 129/219 (58.90%), Query Frame = 1 
Query:  892 LDPIIKYCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRLTLLSN 1545
            LD    YC++   +KA L+ K++D  + +FLQ C  S FSRKLDLWNFLD PRSRL+KYPLL   ILK + ++H D   L + +   + I+  ++ +TGE  C +Y  +L +LE++Q   L+ +  +L   G +K  R     K+H FLF+++LV T+       E   Y +Y  P+P   L  E++ DGEIR+ GS R  FS+   +KN FR+T  S 
Sbjct:  182 LDSYNSYCSNQVAAKALLDHKKQDHRVHDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILKHTANDHPDRQHLDEAINMIQSIVAEINTQTGESECRYYKERLLYLEESQRDMLIDSSRILSCHGELKNNRGA---KLHVFLFQDVLVITRALTHN--EQLWYQLYRQPIPVRDLEWEDLQDGEIRLGGSIRGAFSNTERTKNFFRVTYRSG 395

HSP 2 Score: 66.2402 bits (160), Expect = 7.859e-49
Identity = 45/136 (33.09%), Postives = 71/136 (52.21%), Query Frame = 3 
Query:  462 TTAAIIIGRHDSTSSTHSICKQ----AWIET-ENGRRLGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWVNIGNS 854
            + A I+  R  S  +  +I K+     W ET + G  LG  LS +EI+RQ  I EL  GE D I DLK   K Y +PM KL ++   +   IF  ++ +IP++E  +  L   +  +G  D +G +++ W+   +S
Sbjct:   51 SRAEIVPHRPWSRQAPPTITKRRDSKLWSETFDVG--LGQMLSSKEIKRQEAIFELSQGEQDLIEDLKLAKKAYHDPMLKLSIMTELELNQIFGTLDSLIPLHEDLLSRLREARKPDGSTDHVGHILVDWLPCLDS 184
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Cavefish
Match: arhgef3 (Rho guanine nucleotide exchange factor 3 [Source:NCBI gene;Acc:103038887])

HSP 1 Score: 147.902 bits (372), Expect = 8.748e-49
Identity = 88/219 (40.18%), Postives = 129/219 (58.90%), Query Frame = 1 
Query:  892 LDPIIKYCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRLTLLSN 1545
            LD    YC++   +KA L+ K++D  + +FLQ C  S FSRKLDLWNFLD PRSRL+KYPLL   ILK + ++H D   L + +   + I+  ++ +TGE  C +Y  +L +LE++Q   L+ +  +L   G +K  R     K+H FLF+++LV T+       E   Y +Y  P+P   L  E++ DGEIR+ GS R  FS+   +KN FR+T  S 
Sbjct:  207 LDSYNSYCSNQVAAKALLDHKKQDHRVHDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILKHTANDHPDRQHLDEAINMIQSIVAEINTQTGESECRYYKERLLYLEESQRDMLIDSSRILSCHGELKNNRGA---KLHVFLFQDVLVITRALTHN--EQLWYQLYRQPIPVRDLEWEDLQDGEIRLGGSIRGAFSNTERTKNFFRVTYRSG 420

HSP 2 Score: 66.6254 bits (161), Expect = 8.748e-49
Identity = 45/136 (33.09%), Postives = 71/136 (52.21%), Query Frame = 3 
Query:  462 TTAAIIIGRHDSTSSTHSICKQ----AWIET-ENGRRLGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWVNIGNS 854
            + A I+  R  S  +  +I K+     W ET + G  LG  LS +EI+RQ  I EL  GE D I DLK   K Y +PM KL ++   +   IF  ++ +IP++E  +  L   +  +G  D +G +++ W+   +S
Sbjct:   76 SRAEIVPHRPWSRQAPPTITKRRDSKLWSETFDVG--LGQMLSSKEIKRQEAIFELSQGEQDLIEDLKLAKKAYHDPMLKLSIMTELELNQIFGTLDSLIPLHEDLLSRLREARKPDGSTDHVGHILVDWLPCLDS 209
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Cavefish
Match: arhgef3 (Rho guanine nucleotide exchange factor 3 [Source:NCBI gene;Acc:103038887])

HSP 1 Score: 148.288 bits (373), Expect = 9.741e-49
Identity = 88/219 (40.18%), Postives = 129/219 (58.90%), Query Frame = 1 
Query:  892 LDPIIKYCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRLTLLSN 1545
            LD    YC++   +KA L+ K++D  + +FLQ C  S FSRKLDLWNFLD PRSRL+KYPLL   ILK + ++H D   L + +   + I+  ++ +TGE  C +Y  +L +LE++Q   L+ +  +L   G +K  R     K+H FLF+++LV T+       E   Y +Y  P+P   L  E++ DGEIR+ GS R  FS+   +KN FR+T  S 
Sbjct:  208 LDSYNSYCSNQVAAKALLDHKKQDHRVHDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILKHTANDHPDRQHLDEAINMIQSIVAEINTQTGESECRYYKERLLYLEESQRDMLIDSSRILSCHGELKNNRGA---KLHVFLFQDVLVITRALTHN--EQLWYQLYRQPIPVRDLEWEDLQDGEIRLGGSIRGAFSNTERTKNFFRVTYRSG 421

HSP 2 Score: 66.2402 bits (160), Expect = 9.741e-49
Identity = 45/136 (33.09%), Postives = 71/136 (52.21%), Query Frame = 3 
Query:  462 TTAAIIIGRHDSTSSTHSICKQ----AWIET-ENGRRLGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWVNIGNS 854
            + A I+  R  S  +  +I K+     W ET + G  LG  LS +EI+RQ  I EL  GE D I DLK   K Y +PM KL ++   +   IF  ++ +IP++E  +  L   +  +G  D +G +++ W+   +S
Sbjct:   77 SRAEIVPHRPWSRQAPPTITKRRDSKLWSETFDVG--LGQMLSSKEIKRQEAIFELSQGEQDLIEDLKLAKKAYHDPMLKLSIMTELELNQIFGTLDSLIPLHEDLLSRLREARKPDGSTDHVGHILVDWLPCLDS 210
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Sea Lamprey
Match: net1 (neuroepithelial cell transforming 1 [Source:ZFIN;Acc:ZDB-GENE-041121-18])

HSP 1 Score: 129.798 bits (325), Expect = 2.633e-44
Identity = 74/199 (37.19%), Postives = 118/199 (59.30%), Query Frame = 1 
Query:  910 YCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSD 1503
            YC +   +KA L++K++D  + +FLQ C  S FSRKL+LW+FLD PRSRL+KYPLL   IL+ + +EH D   L + +   + ++  ++ +TGE  C ++  KLD+L++ Q   L+     L L G ++  R     K+   LF ++LV ++     + +   Y VY  P+P   L LE++ DGE++M GSFR  F ++
Sbjct:  203 YCANQVAAKALLDQKKQDPRVQDFLQRCLESPFSRKLELWSFLDVPRSRLVKYPLLLREILRHTPNEHPDQQCLEEAISIIQGVVADVNTRTGESECCYFRDKLDYLDERQRDPLIATSRTLHLHGELRNNRGT---KLFVLLFGDVLVLSRPASRGN-DGCCYQVYRQPIPLRDLRLEDLQDGEVKMGGSFRGAFGNN 397

HSP 2 Score: 67.3958 bits (163), Expect = 2.633e-44
Identity = 33/104 (31.73%), Postives = 57/104 (54.81%), Query Frame = 3 
Query:  573 SKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWVNIGNSLQLNHVNDLV 884
            S+ EI+RQ  I EL  GE D I DLK   K Y++PM KL ++ + +   IF  ++ +IP++E  +  L+  +  NG  + +G +++ W+   N+      N + 
Sbjct:  106 SRSEIKRQEAIFELAQGEQDLIEDLKLAKKAYRDPMLKLSIMTAVELAQIFGALDSLIPLHEDLLTGLQKARKPNGATERVGHILVEWLPCLNAYTCYCANQVA 209
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Sea Lamprey
Match: net1 (neuroepithelial cell transforming 1 [Source:ZFIN;Acc:ZDB-GENE-041121-18])

HSP 1 Score: 131.724 bits (330), Expect = 6.249e-43
Identity = 82/217 (37.79%), Postives = 122/217 (56.22%), Query Frame = 1 
Query:  892 LDPIIKYCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTK--QTGEESIESTRYTVYGNPLPTNKLILENINDGEIRMGSFRSTFSSDRGSKNVFRLTL 1536
            L+    YC +   +KA L++K++D  + +FLQ C  S FSRKL+LW+FLD PRSRL+KYPLL   I + + +EH D   L    +    IL  ++ +TGE  C FY  +L+F++       + +  +L   G ++  R     K+H FLF+E+LV T+    GE S     Y V+  P+PT +L LE+I +   R GSFR  F  +   KN FR+ +
Sbjct:  177 LNAYTSYCGNQVAAKALLDQKKRDPRVQDFLQRCIESPFSRKLELWSFLDVPRSRLVKYPLLLREIERHTPAEHPDVDLLRHATEIVRGILSEINLRTGESECCFYRERLEFVDARHRDPRIASARLLHCHGELRNQRGT---KLHVFLFDEVLVLTRPGARGERSF----YQVFRQPVPTAELRLEDITEPGGR-GSFRGPFGPNDRGKNAFRVGV 385

HSP 2 Score: 60.8474 bits (146), Expect = 6.249e-43
Identity = 34/108 (31.48%), Postives = 56/108 (51.85%), Query Frame = 3 
Query:  531 WIETENGRRLGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWVNIGNS 854
            W ET   R  G+ L   EI+RQ  I EL  GE   I DL+   K Y +PM KL ++   +   IF +++  IP+++  +  LE  +  +G +  +G  ++ W+   N+
Sbjct:   73 WSETFTVRD-GDALPSSEIKRQETIFELFQGEQALIEDLQLAKKAYHDPMLKLGIMNEEELTKIFGDLDSFIPLHQDLVRRLEEARGPDGTVKEVGQTLVTWLPCLNA 179
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004597.1 (pep scaffold:Pmarinus_7.0:GL479903:23161:30151:1 gene:ENSPMAG00000004180.1 transcript:ENSPMAT00000004597.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 67.781 bits (164), Expect = 2.644e-13
Identity = 35/103 (33.98%), Postives = 55/103 (53.40%), Query Frame = 3 
Query:  531 WIETENGRRLGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWV 839
            W ET         LS  E++RQ +I EL  GE D I DL+   K Y +PM  L ++   +   IF +++  IP++E  +  L+G +  +G I  +G ++L WV
Sbjct:  104 WCETFTDAAACQQLSGHELKRQEVIFELFRGEHDLIKDLQVAKKAYHDPMLTLAIMTEEELAQIFGSLDSFIPLHEDLVRRLDGARQGDGSIHHVGPLLLDWV 206
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Nematostella
Match: EDO37874 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEJ8])

HSP 1 Score: 128.257 bits (321), Expect = 9.404e-41
Identity = 96/317 (30.28%), Postives = 142/317 (44.79%), Query Frame = 1 
Query:  904 IKYCTHLYFSKAFLEEKRK-DKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXF------------------------------------EIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRLTLLSNFIPEIEFDDHNDYNERALEDTFASNDKYEQSPYDGRLLKNSQTILQTSQLEEKQLWLNTLRKVVA 1740
            +KYC + + +KA L+EK K D  + +FLQ C AS FSRKLDLW+FLD+PRSRL+KYPL+ + I+K   + H           +F                                    E I+  +D+KTGE  C   L ++ FL  NQ    +     L+  G +K   + H  K+HAFLFE++ + T+        S  Y V+  PL    L +E++ DG++R+ GSF++  S    S+NV R++           D HN  +                              LQ S   +K+ WLN LR +V+
Sbjct:  312 VKYCANQFEAKAMLDEKMKSDNNVKDFLQRCQASPFSRKLDLWSFLDSPRSRLVKYPLMLKSIMKLVSTIHLRLDSHQVQQVQFTLDSHQVRLTLDFYLVQQTPRDHPDRKLLEDAIACIETIIEDVDQKTGEAKCQCVLSRIVFLYDNQMCPELFKSKRLLCSGVLK---NKHGTKLHAFLFEKVFLLTRPATRGGRSS--YQVFTEPLLAEYLFVEDLPDGDVRLGGSFKTAISRLATSRNVLRIS---------STDRHNGQSH----------------------------TLQASSEPDKRQWLNALRSIVS 586

HSP 2 Score: 57.7658 bits (138), Expect = 9.404e-41
Identity = 31/92 (33.70%), Postives = 52/92 (56.52%), Query Frame = 3 
Query:  564 NNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDH-NGIIDGIGLVVLRW 836
              LS  ++ RQ  I+EL +GE D ++DL  + + Y +PM KL+L+   +   IF  IE ++ I+   I  L+  +   +G+ D IG ++L W
Sbjct:  213 QTLSPMQLRRQEAIYELSSGEEDVVSDLTMMQEVYYKPMYKLKLMSEYEFTTIFGYIETLLEIHSDIIVKLKAARSSADGMTDSIGQIMLEW 304
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Nematostella
Match: EDO33665 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRI8])

HSP 1 Score: 45.0542 bits (105), Expect = 2.219e-10
Identity = 25/93 (26.88%), Postives = 52/93 (55.91%), Query Frame = 3 
Query:  552 RRLGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVL 830
            R+    L ++EI+RQ  IHEL+  E   + +LK + K + +PM+K+ ++       +F N++++I I+   +  ++  +    +I  IG ++L
Sbjct:    1 RQTIKKLKQKEIKRQEFIHELIYTEKTHVRNLKVLDKVFHKPMKKMNIMPYEYIKKLFPNLQELIEIHGDLLQSMKKREAEGEVIQCIGDIML 93

HSP 2 Score: 38.5058 bits (88), Expect = 2.219e-10
Identity = 22/58 (37.93%), Postives = 31/58 (53.45%), Query Frame = 1 
Query:  928 FSKAFLEE----KRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERI 1089
            + K  LEE    ++KD ++ +F+  C AS   R+L L   +     RL KYPLL E I
Sbjct:  114 YQKNALEELRQRQKKDPKLLQFIMNCEASPLCRRLKLNEIISTSYQRLTKYPLLLEGI 171
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Nematostella
Match: EDO32824 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STY6])

HSP 1 Score: 43.1282 bits (100), Expect = 1.699e-9
Identity = 28/98 (28.57%), Postives = 53/98 (54.08%), Query Frame = 3 
Query:  525 QAWIETENGRRLGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIG 818
            +AW  T + + L   ++ ++I+RQ++IHEL+  E+  +  LK + K +   M  L  L       +F  +E+++ +  TF+  L+  +D   I+D IG
Sbjct:  301 EAWSVTVDKKTL-KKMTAKDIKRQDVIHELIQTEVHYVRTLKIMHKIFYNGMVTLLNLSRETVDQLFPQLEELLDLNGTFLTRLKHRQDEGIIVDKIG 397

HSP 2 Score: 37.3502 bits (85), Expect = 1.699e-9
Identity = 22/62 (35.48%), Postives = 33/62 (53.23%), Query Frame = 1 
Query:  910 YCTHLYFSKAFLEEK--RKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERI 1089
            +C+H +     L +K  R DK   +F++ C  +KF R+L +   +     RL KYPLL E I
Sbjct:  419 FCSH-HIEAVELYKKLLRTDKRFADFVKKCGLNKFCRRLSVPECITLVTQRLTKYPLLIEAI 479
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Medaka
Match: ENSORLT00000031678.1 (neuroepithelial cell-transforming gene 1 protein [Source:NCBI gene;Acc:101174345])

HSP 1 Score: 151.369 bits (381), Expect = 6.897e-49
Identity = 83/211 (39.34%), Postives = 130/211 (61.61%), Query Frame = 1 
Query:  910 YCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRLTLL 1539
            YC++   +KA L++K++D+ + +FLQ C  S FSRKLDLW+FLD PRSRL+KYPLL   IL+ +  +H D + L   +   + IL  ++ + GE  C +Y+ KL++L++ Q   L+ N   L+  G +   R+    ++H FLF E+LV T+       + + + V   P+P   L LE++ DGEIRM GSFR  F++   +KNVFR++ +
Sbjct:  269 YCSNQLAAKALLDQKKQDRRVQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLREILRHTPPDHPDVTSLEKAIAIIQEILSDINVRKGESECQYYIDKLEYLDEKQRDPLIDNCKTLLCHGEL---RTKSGSRLHVFLFSELLVLTRPVTRN--DKSCFQVCRRPIPVKDLALEDLQDGEIRMGGSFRGAFTNGEKAKNVFRVSSM 474

HSP 2 Score: 63.5438 bits (153), Expect = 6.897e-49
Identity = 32/92 (34.78%), Postives = 53/92 (57.61%), Query Frame = 3 
Query:  564 NNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWV 839
            +  S +EI+RQ  I+EL  GE D I DL+   K Y +PM KL ++   +  +IF +++  IP++E  +  L  E   +G +  IG +V+ W+
Sbjct:  169 STFSTKEIKRQEAIYELFRGEQDLIEDLQLARKAYHDPMLKLSIMTEEELAHIFGDLDAYIPLHEDLLIKLTEETGSDGTVAQIGQIVIDWL 260
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Medaka
Match: ENSORLT00000004804.2 (neuroepithelial cell-transforming gene 1 protein [Source:NCBI gene;Acc:101174345])

HSP 1 Score: 150.984 bits (380), Expect = 1.479e-48
Identity = 83/209 (39.71%), Postives = 129/209 (61.72%), Query Frame = 1 
Query:  910 YCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRLT 1533
            YC++   +KA L++K++D+ + +FLQ C  S FSRKLDLW+FLD PRSRL+KYPLL   IL+ +  +H D + L   +   + IL  ++ + GE  C +Y+ KL++L++ Q   L+ N   L+  G +   R+    ++H FLF E+LV T+       + + + V   P+P   L LE++ DGEIRM GSFR  F++   +KNVFR++
Sbjct:  207 YCSNQLAAKALLDQKKQDRRVQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLREILRHTPPDHPDVTSLEKAIAIIQEILSDINVRKGESECQYYIDKLEYLDEKQRDPLIDNCKTLLCHGEL---RTKSGSRLHVFLFSELLVLTRPVTRN--DKSCFQVCRRPIPVKDLALEDLQDGEIRMGGSFRGAFTNGEKAKNVFRVS 410

HSP 2 Score: 62.7734 bits (151), Expect = 1.479e-48
Identity = 32/92 (34.78%), Postives = 53/92 (57.61%), Query Frame = 3 
Query:  564 NNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWV 839
            +  S +EI+RQ  I+EL  GE D I DL+   K Y +PM KL ++   +  +IF +++  IP++E  +  L  E   +G +  IG +V+ W+
Sbjct:  107 STFSTKEIKRQEAIYELFRGEQDLIEDLQLARKAYHDPMLKLSIMTEEELAHIFGDLDAYIPLHEDLLIKLTEETGSDGTVAQIGQIVIDWL 198
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Medaka
Match: net1 (neuroepithelial cell transforming 1 [Source:NCBI gene;Acc:101166022])

HSP 1 Score: 150.599 bits (379), Expect = 1.702e-48
Identity = 86/214 (40.19%), Postives = 131/214 (61.21%), Query Frame = 1 
Query:  892 LDPIIKYCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRL 1530
            LD    YC++   +KA L++K++D  + +FLQ C  S FSRKLDLW+FLD PRSRL+KYPLL + IL+ +  +H D   L + +     +L  ++ K GE  C +Y+ KL++LE+ Q   L++    L+  G +   R+    K+H FLF E+LV T+       E   + VY  P+P + L+LE++ DG++RM GSFR  FS+   +KN+FR+
Sbjct:  181 LDAYKNYCSNQLAAKALLDQKKQDPRVQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILRHTPVDHPDKGSLEEAITIIHGVLSDINVKKGESECQYYIEKLEYLEERQKDPLMEQCRSLLCHGEL---RNKSGTKLHVFLFTELLVLTRPVTRN--ERQCFQVYRQPIPVHDLVLEDLQDGDVRMGGSFRGAFSNADKAKNIFRV 389

HSP 2 Score: 63.1586 bits (152), Expect = 1.702e-48
Identity = 41/141 (29.08%), Postives = 62/141 (43.97%), Query Frame = 3 
Query:  453 YGITTAAIIIGRHDSTSSTHSICKQAWIETENGRR------------LGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWV 839
            +G T  A   G   S  +    C +    T   RR                 S +EI+RQ  I EL  GE D I DL+   K Y +PM KL ++   +  +IF N++  IP++E  +  L      +G +  IG +V+ W+
Sbjct:   38 FGQTIQASFRGDGKSPGAPQKPCGKVPAPTPPKRRNSILWSETLDIHQKGTFSTKEIKRQEAIFELSRGEQDLIEDLQLARKAYHDPMLKLSIMSEVELTHIFGNLDAYIPLHEELLAQLSKATRPDGTVGQIGQIVINWL 178
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Medaka
Match: net1 (neuroepithelial cell transforming 1 [Source:NCBI gene;Acc:101166022])

HSP 1 Score: 150.599 bits (379), Expect = 1.848e-48
Identity = 86/214 (40.19%), Postives = 131/214 (61.21%), Query Frame = 1 
Query:  892 LDPIIKYCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRL 1530
            LD    YC++   +KA L++K++D  + +FLQ C  S FSRKLDLW+FLD PRSRL+KYPLL + IL+ +  +H D   L + +     +L  ++ K GE  C +Y+ KL++LE+ Q   L++    L+  G +   R+    K+H FLF E+LV T+       E   + VY  P+P + L+LE++ DG++RM GSFR  FS+   +KN+FR+
Sbjct:  205 LDAYKNYCSNQLAAKALLDQKKQDPRVQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILRHTPVDHPDKGSLEEAITIIHGVLSDINVKKGESECQYYIEKLEYLEERQKDPLMEQCRSLLCHGEL---RNKSGTKLHVFLFTELLVLTRPVTRN--ERQCFQVYRQPIPVHDLVLEDLQDGDVRMGGSFRGAFSNADKAKNIFRV 413

HSP 2 Score: 63.1586 bits (152), Expect = 1.848e-48
Identity = 41/141 (29.08%), Postives = 62/141 (43.97%), Query Frame = 3 
Query:  453 YGITTAAIIIGRHDSTSSTHSICKQAWIETENGRR------------LGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWV 839
            +G T  A   G   S  +    C +    T   RR                 S +EI+RQ  I EL  GE D I DL+   K Y +PM KL ++   +  +IF N++  IP++E  +  L      +G +  IG +V+ W+
Sbjct:   62 FGQTIQASFRGDGKSPGAPQKPCGKVPAPTPPKRRNSILWSETLDIHQKGTFSTKEIKRQEAIFELSRGEQDLIEDLQLARKAYHDPMLKLSIMSEVELTHIFGNLDAYIPLHEELLAQLSKATRPDGTVGQIGQIVINWL 202
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Medaka
Match: arhgef3 (Rho guanine nucleotide exchange factor 3 [Source:NCBI gene;Acc:101162119])

HSP 1 Score: 146.747 bits (369), Expect = 1.183e-47
Identity = 83/209 (39.71%), Postives = 128/209 (61.24%), Query Frame = 1 
Query:  910 YCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRM-GSFRSTFSSDRGSKNVFRLT 1533
            YC++   +KA L++K++D+ + +FLQ C  S FSRKLDLWNFLD PRSRL+KYPLL   ILK +  +H D   L + +   + ++  ++++TGE  C +Y  +L + E+ Q   L+     L   G +K  RSV   K+H FLF+ ILV T+     + +   Y +   P+P  +L LE+++DGE+R+ GS R  FS+   +KN FR++
Sbjct:  174 YCSNQVKAKALLDQKKQDRRVQDFLQRCLQSPFSRKLDLWNFLDIPRSRLVKYPLLLREILKHTAIDHPDRQHLDEAMLMVQSVVADINRQTGESECQYYKERLLYSEEGQRDQLIDRSKTLCCHGELKNNRSV---KLHVFLFQNILVITRSVSLHN-QPVSYQLCRQPIPLTRLDLEDLSDGEMRVGGSIRGAFSNTERTKNFFRVS 378

HSP 2 Score: 63.929 bits (154), Expect = 1.183e-47
Identity = 36/109 (33.03%), Postives = 57/109 (52.29%), Query Frame = 3 
Query:  531 WIETENGRR-LGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWVNIGNS 854
            W ET + R      LS +EI+RQ  I EL  GE D + DLK   K Y +PM KL ++   +   IF  +E +IP++E  +  L   +  +G  + +G ++  W+   +S
Sbjct:   62 WSETFDVRTGATQTLSPKEIKRQEAIFELAQGEQDLVEDLKLAKKAYHDPMLKLSIMTEQELNQIFGTLESLIPLHEDLLGRLRDARKPDGSTEHVGHILTAWLPCLSS 170
[Close]
BLAST of Neuroepithelial cell transforming 1 vs. Planmine SMEST
Match: SMESG000035468.1 (SMESG000035468.1)

HSP 1 Score: 549.666 bits (1415), Expect = 0.000e+0
Identity = 293/293 (100.00%), Postives = 293/293 (100.00%), Query Frame = 1 
Query:  883 SDLLDPIIKYCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERIXXXXXXXXXXXXXXXXXXXXFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRMGSFRSTFSSDRGSKNVFRLTLLSNFIPEIEFDDHNDYNERALEDTFASNDKYEQSPYDGRLLKNSQTILQTSQLEEKQLWLNTLRKVVAREIKREN 1761
            SDLLDPIIKYCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERILKSSDSEHSDSSDLVDVLKKFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRMGSFRSTFSSDRGSKNVFRLTLLSNFIPEIEFDDHNDYNERALEDTFASNDKYEQSPYDGRLLKNSQTILQTSQLEEKQLWLNTLRKVVAREIKREN
Sbjct:  275 SDLLDPIIKYCTHLYFSKAFLEEKRKDKEIGEFLQCCSASKFSRKLDLWNFLDNPRSRLMKYPLLFERILKSSDSEHSDSSDLVDVLKKFEIILLSLDKKTGEEMCNFYLGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVFTKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRMGSFRSTFSSDRGSKNVFRLTLLSNFIPEIEFDDHNDYNERALEDTFASNDKYEQSPYDGRLLKNSQTILQTSQLEEKQLWLNTLRKVVAREIKREN 567

HSP 2 Score: 496.508 bits (1277), Expect = 0.000e+0
Identity = 255/277 (92.06%), Postives = 257/277 (92.78%), Query Frame = 3 
Query:   18 MKRFNIFNRNRKDKEKNPENFDETFINNGLNDHHDTFGLKEDLDFYMIKNKNHETAEDAISIRSVDCKNKIKWNKRIVNFEKGEIPSRINSPKYQFVKNTDQKFNYDNLXXXXX-XXXXXXXXXXXXXXXXXXXHDGEDKRSESPLYGITTAAIIIGRHDSTSSTHSICKQAWIETENGRRLGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWVNI 845
            MKRFNIFNRNRKDKEKNPENFDETFINNGLNDHHDTFGLKEDLDFYMIKNKNHETAEDAISIRSVDCKNKIKWNKRIVNFEKGEIPSRINSPKYQFVKNTDQKFNYDNLIKKMI          K         HDGEDKRSESPLYGITTAAIIIGRHDSTSSTHSICKQAWIETENGRRLGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRW ++
Sbjct:    1 MKRFNIFNRNRKDKEKNPENFDETFINNGLNDHHDTFGLKEDLDFYMIKNKNHETAEDAISIRSVDCKNKIKWNKRIVNFEKGEIPSRINSPKYQFVKNTDQKFNYDNLIKKMIHIKNENIEIKKLECEINKNLHDGEDKRSESPLYGITTAAIIIGRHDSTSSTHSICKQAWIETENGRRLGNNLSKQEIERQNIIHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPIYETFIDLLEGEKDHNGIIDGIGLVVLRWSDL 277
The following BLAST results are available for this feature:
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
NET16.431e-5136.33neuroepithelial cell transforming 1 [Source:HGNC S... [more]
NET16.809e-5136.33neuroepithelial cell transforming 1 [Source:HGNC S... [more]
ARHGEF37.452e-4941.15Rho guanine nucleotide exchange factor 3 [Source:H... [more]
ARHGEF39.020e-4941.15Rho guanine nucleotide exchange factor 3 [Source:H... [more]
ARHGEF39.252e-4941.15Rho guanine nucleotide exchange factor 3 [Source:H... [more]
back to top
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
net13.180e-4938.94neuroepithelial cell transforming 1 [Source:ZFIN;A... [more]
net14.079e-4938.94neuroepithelial cell transforming 1 [Source:ZFIN;A... [more]
arhgef3l7.470e-4939.53Rho guanine nucleotide exchange factor (GEF) 3, li... [more]
arhgef33.027e-4841.35Rho guanine nucleotide exchange factor (GEF) 3 [So... [more]
net18.131e-4338.97neuroepithelial cell transforming 1 [Source:ZFIN;A... [more]
back to top
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
arhgef3.21.276e-4740.38Rho guanine nucleotide exchange factor 3 [Source:N... [more]
arhgef3.21.319e-4740.38Rho guanine nucleotide exchange factor 3 [Source:N... [more]
arhgef3.21.351e-4740.38Rho guanine nucleotide exchange factor 3 [Source:N... [more]
arhgef3.21.622e-4740.38Rho guanine nucleotide exchange factor 3 [Source:N... [more]
arhgef3.21.622e-4740.38Rho guanine nucleotide exchange factor 3 [Source:N... [more]
back to top
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Net12.518e-4939.90neuroepithelial cell transforming gene 1 [Source:M... [more]
Net12.925e-4934.53neuroepithelial cell transforming gene 1 [Source:M... [more]
Arhgef34.846e-4941.15Rho guanine nucleotide exchange factor (GEF) 3 [So... [more]
Arhgef36.062e-4941.15Rho guanine nucleotide exchange factor (GEF) 3 [So... [more]
Arhgef38.034e-4941.15Rho guanine nucleotide exchange factor (GEF) 3 [So... [more]
back to top
BLAST of Neuroepithelial cell transforming 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q7Z628|ARHG8_HUMAN2.987e-5036.33Neuroepithelial cell-transforming gene 1 protein O... [more]
sp|Q9Z206|ARHG8_MOUSE1.525e-4839.90Neuroepithelial cell-transforming gene 1 protein O... [more]
sp|Q9N0A8|ARHG3_MACFA3.828e-4841.15Rho guanine nucleotide exchange factor 3 OS=Macaca... [more]
sp|Q9NR81|ARHG3_HUMAN3.957e-4841.15Rho guanine nucleotide exchange factor 3 OS=Homo s... [more]
sp|Q5ZLX4|ARHG3_CHICK4.517e-4842.11Rho guanine nucleotide exchange factor 3 OS=Gallus... [more]
back to top
BLAST of Neuroepithelial cell transforming 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A402FXK41.016e-4940.38Uncharacterized protein OS=Paroedura picta OX=1436... [more]
A0A3B3ZJB61.077e-4935.25Neuroepithelial cell transforming 1 OS=Periophthal... [more]
A0A3B3TZ942.018e-4939.90Neuroepithelial cell transforming 1 OS=Poecilia la... [more]
A0A3B3VEB83.057e-4939.71Neuroepithelial cell transforming 1 OS=Poecilia la... [more]
A0A3B3WPG83.523e-4939.71Neuroepithelial cell transforming 1 OS=Poecilia me... [more]
back to top
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
arhgef3l7.796e-5038.14rho guanine nucleotide exchange factor 3-like [Sou... [more]
arhgef3l8.685e-5038.14rho guanine nucleotide exchange factor 3-like [Sou... [more]
arhgef37.859e-4940.18Rho guanine nucleotide exchange factor 3 [Source:N... [more]
arhgef38.748e-4940.18Rho guanine nucleotide exchange factor 3 [Source:N... [more]
arhgef39.741e-4940.18Rho guanine nucleotide exchange factor 3 [Source:N... [more]
back to top
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
net12.633e-4437.19neuroepithelial cell transforming 1 [Source:ZFIN;A... [more]
net16.249e-4337.79neuroepithelial cell transforming 1 [Source:ZFIN;A... [more]
ENSPMAT00000004597.12.644e-1333.98pep scaffold:Pmarinus_7.0:GL479903:23161:30151:1 g... [more]
back to top
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 3
Match NameE-valueIdentityDescription
EDO378749.404e-4130.28Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO336652.219e-1026.88Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO328241.699e-928.57Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of Neuroepithelial cell transforming 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000031678.16.897e-4939.34neuroepithelial cell-transforming gene 1 protein [... [more]
ENSORLT00000004804.21.479e-4839.71neuroepithelial cell-transforming gene 1 protein [... [more]
net11.702e-4840.19neuroepithelial cell transforming 1 [Source:NCBI g... [more]
net11.848e-4840.19neuroepithelial cell transforming 1 [Source:NCBI g... [more]
arhgef31.183e-4739.71Rho guanine nucleotide exchange factor 3 [Source:N... [more]
back to top
BLAST of Neuroepithelial cell transforming 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000035468.10.000e+0100.00SMESG000035468.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30021221 ID=SMED30021221|Name=Neuroepithelial cell transforming 1|organism=Schmidtea mediterranea sexual|type=transcript|length=1856bp
TAATTAATCATTCCTTTATGAAAAGATTTAATATCTTTAACAGAAATCGA
AAAGACAAAGAAAAAAATCCCGAAAATTTTGACGAAACCTTTATTAATAA
TGGATTAAATGATCATCATGATACATTTGGTTTGAAAGAAGACTTGGATT
TTTACATGATCAAAAATAAAAATCATGAAACGGCAGAAGATGCAATAAGC
ATTAGAAGCGTCGATTGTAAAAACAAAATAAAATGGAATAAACGAATTGT
GAATTTTGAGAAAGGAGAAATTCCTAGCAGAATAAACAGTCCAAAATATC
AGTTTGTAAAAAATACAGATCAAAAGTTCAATTATGATAATTTAATAAAA
AAGATGATTCATATTAAAAATGAAAACATCGAAATCAAGAAATTGGAATG
TGAAATTAATAAAAACCACGATGGTGAAGACAAAAGATCCGAATCTCCAT
TATATGGAATCACAACGGCTGCTATTATCATCGGTCGACACGATTCAACA
TCTTCAACTCATTCCATTTGTAAACAAGCTTGGATTGAAACAGAAAATGG
CCGACGGTTGGGAAACAATTTAAGTAAACAAGAAATCGAAAGACAAAATA
TTATCCACGAGTTATTAACTGGAGAAATAGATTCCATCAATGATTTGAAA
GGAGTCATTAAACATTATAAAGAGCCAATGGAAAAGCTTCAATTGCTAGG
ATCAGGCGATTCTTTCAACATATTTTATAATATCGAGAAAATCATTCCAA
TCTATGAAACATTTATTGATTTGTTAGAAGGAGAAAAAGATCACAATGGA
ATCATTGACGGAATTGGACTAGTTGTGTTGCGATGGGTAAATATTGGAAA
TTCTCTACAACTGAATCATGTTAATGATTTAGTCTGACTTGTTGGATCCA
ATTATTAAGTATTGTACTCATTTGTACTTTTCTAAAGCTTTCCTAGAAGA
AAAACGTAAGGATAAAGAAATTGGGGAATTTTTGCAATGTTGTTCCGCAT
CAAAGTTCAGTCGAAAATTGGATCTATGGAATTTCCTCGATAATCCCAGA
AGTCGCCTTATGAAGTATCCTCTATTATTTGAAAGAATTTTAAAATCTAG
CGATTCTGAACATTCTGACTCGTCGGATTTGGTTGATGTTTTGAAGAAAT
TTGAAATTATTTTATTATCATTAGACAAAAAGACTGGTGAAGAAATGTGT
AATTTCTATCTGGGGAAACTCGATTTCCTTGAACAAAATCAATATATTAA
TTTAGTAAAAAATCAAAATGTTCTTATTCTTGAGGGAAATGTAAAAATTG
GCCGATCAGTTCATTTTCACAAAGTTCATGCATTTTTATTCGAAGAAATT
TTAGTTTTTACGAAGCAAACTGGAGAAGAAAGCATAGAAAGCACCCGGTA
CACGGTTTATGGCAATCCGTTACCTACTAATAAATTAATTCTGGAAAATA
TAAATGATGGCGAAATTAGAATGGGCTCATTTAGGTCGACTTTCAGTTCA
GACAGAGGGAGTAAGAACGTCTTTCGTTTAACTCTGTTGTCAAATTTTAT
TCCTGAAATTGAGTTTGATGATCATAATGATTACAATGAAAGAGCCTTGG
AAGATACATTTGCTAGTAATGATAAATACGAACAGTCTCCTTATGATGGG
CGTTTATTAAAGAATTCTCAAACAATTCTTCAAACTTCTCAACTAGAAGA
AAAGCAATTATGGTTAAACACATTAAGAAAAGTCGTTGCTAGGGAAATTA
AACGAGAAAATTAAATAACTTTATATGTGATTAATCTTTCATAAAATTAA
TATTTTTATTAATTTAGTGATATGTCATGATTTGGTATGATTTATTCACT
CAACGC
back to top

protein sequence of SMED30021221-orf-1

>SMED30021221-orf-1 ID=SMED30021221-orf-1|Name=SMED30021221-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=235bp
MKYPLLFERILKSSDSEHSDSSDLVDVLKKFEIILLSLDKKTGEEMCNFY
LGKLDFLEQNQYINLVKNQNVLILEGNVKIGRSVHFHKVHAFLFEEILVF
TKQTGEESIESTRYTVYGNPLPTNKLILENINDGEIRMGSFRSTFSSDRG
SKNVFRLTLLSNFIPEIEFDDHNDYNERALEDTFASNDKYEQSPYDGRLL
KNSQTILQTSQLEEKQLWLNTLRKVVAREIKREN*
back to top

protein sequence of SMED30021221-orf-2

>SMED30021221-orf-2 ID=SMED30021221-orf-2|Name=SMED30021221-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=295bp
INHSFMKRFNIFNRNRKDKEKNPENFDETFINNGLNDHHDTFGLKEDLDF
YMIKNKNHETAEDAISIRSVDCKNKIKWNKRIVNFEKGEIPSRINSPKYQ
FVKNTDQKFNYDNLIKKMIHIKNENIEIKKLECEINKNHDGEDKRSESPL
YGITTAAIIIGRHDSTSSTHSICKQAWIETENGRRLGNNLSKQEIERQNI
IHELLTGEIDSINDLKGVIKHYKEPMEKLQLLGSGDSFNIFYNIEKIIPI
YETFIDLLEGEKDHNGIIDGIGLVVLRWVNIGNSLQLNHVNDLV*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000136whole organism
PLANA:0002089reproductive organ
Vocabulary: INTERPRO
TermDefinition
IPR035899DBL_dom_sf
IPR011993PH-like_dom_sf
IPR000219DH-domain
Vocabulary: molecular function
TermDefinition
GO:0005089Rho guanyl-nucleotide exchange factor activity
GO:0005085guanyl-nucleotide exchange factor activity
Vocabulary: biological process
TermDefinition
GO:0035023regulation of Rho protein signal transduction
GO:0035556intracellular signal transduction
GO:0043547positive regulation of GTPase activity
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 121..141
NoneNo IPR availablePANTHERPTHR46006FAMILY NOT NAMEDcoord: 52..280
NoneNo IPR availablePANTHERPTHR46006:SF6coord: 52..280
IPR000219Dbl homology (DH) domainPFAMPF00621RhoGEFcoord: 201..278
e-value: 2.1E-6
score: 28.1
IPR000219Dbl homology (DH) domainPROSITEPS50010DH_2coord: 197..295
score: 10.956
IPR035899Dbl homology (DH) domain superfamilyGENE3DG3DSA:1.20.900.10coord: 181..289
e-value: 2.7E-15
score: 58.3
IPR035899Dbl homology (DH) domain superfamilySUPERFAMILYSSF48065DBL homology domain (DH-domain)coord: 189..281