Mitogen-activated protein kinase
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30021209 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 14
Homology
BLAST of Mitogen-activated protein kinase vs. Ensembl Human
Match: MAPK14 (mitogen-activated protein kinase 14 [Source:HGNC Symbol;Acc:HGNC:6876]) HSP 1 Score: 433.335 bits (1113), Expect = 4.199e-144 Identity = 207/347 (59.65%), Postives = 260/347 (74.93%), Query Frame = 1
Query: 1546 FQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTP 2586
F + + W VP RY+NL+P+G GAYGSVCAAFD K +VA+KKL+RPF S +AKRTYREL+++ HM HEN++ L+D +TP + E F+DVYL+T LMGADLN I++ Q+L ++HVQFL+YQILRGLKY+HS++IIHRDLKPSN+AVNEDCELKILDFGLAR TD+EMTGYVATRWYRAPEIML+WMHY VDIWSVGCIMAEL T + LFPG DHIDQLK I+ L GTP E + KI SE AR +I+ Q P+ +F + F + A+DLL++MLVLD D+RI+A ALAH Y A YHD DEP A + E + D+ ++ WK +D + +F P
Sbjct: 8 FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLTQM-PKMNFANVF--IGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESR-DLLIDEWKSLTYDEVISFVP 350
BLAST of Mitogen-activated protein kinase vs. Ensembl Human
Match: MAPK11 (mitogen-activated protein kinase 11 [Source:HGNC Symbol;Acc:HGNC:6873]) HSP 1 Score: 433.335 bits (1113), Expect = 4.675e-144 Identity = 205/347 (59.08%), Postives = 263/347 (75.79%), Query Frame = 1
Query: 1540 AEFQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNF 2580
A F + + W VP R + L P+G GAYGSVC+A+D +L+++VA+KKL+RPF S +A+RTYREL+++ H+ HEN++ L+D +TP ++ E FS+VYL+T LMGADLN I++ Q L +EHVQFLVYQ+LRGLKY+HS+ IIHRDLKPSN+AVNEDCEL+ILDFGLARQ DEEMTGYVATRWYRAPEIML+WMHY VDIWSVGCIMAEL K LFPG+D+IDQLK+IME+ GTP E + KI SE AR +I + + P+KD +S F + AIDLL RMLVLD D+R+SA +ALAH Y + YHD DEP A + + +E K + LE WK+ + + +F
Sbjct: 6 AGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYI-QSLPPMPQKDLSSIF--RGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPEDEPEAEPYDESVEAK-ERTLEEWKELTYQEVLSF 348
BLAST of Mitogen-activated protein kinase vs. Ensembl Human
Match: MAPK11 (mitogen-activated protein kinase 11 [Source:HGNC Symbol;Acc:HGNC:6873]) HSP 1 Score: 433.335 bits (1113), Expect = 4.675e-144 Identity = 205/347 (59.08%), Postives = 263/347 (75.79%), Query Frame = 1
Query: 1540 AEFQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNF 2580
A F + + W VP R + L P+G GAYGSVC+A+D +L+++VA+KKL+RPF S +A+RTYREL+++ H+ HEN++ L+D +TP ++ E FS+VYL+T LMGADLN I++ Q L +EHVQFLVYQ+LRGLKY+HS+ IIHRDLKPSN+AVNEDCEL+ILDFGLARQ DEEMTGYVATRWYRAPEIML+WMHY VDIWSVGCIMAEL K LFPG+D+IDQLK+IME+ GTP E + KI SE AR +I + + P+KD +S F + AIDLL RMLVLD D+R+SA +ALAH Y + YHD DEP A + + +E K + LE WK+ + + +F
Sbjct: 6 AGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYI-QSLPPMPQKDLSSIF--RGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPEDEPEAEPYDESVEAK-ERTLEEWKELTYQEVLSF 348
BLAST of Mitogen-activated protein kinase vs. Ensembl Human
Match: MAPK14 (mitogen-activated protein kinase 14 [Source:HGNC Symbol;Acc:HGNC:6876]) HSP 1 Score: 426.402 bits (1095), Expect = 2.225e-141 Identity = 202/337 (59.94%), Postives = 258/337 (76.56%), Query Frame = 1
Query: 1576 WTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTP 2586
W VP RY+NL+P+G GAYGSVCAAFD K +VA+KKL+RPF S +AKRTYREL+++ HM HEN++ L+D +TP + E F+DVYL+T LMGADLN I++ Q+L ++HVQFL+YQILRGLKY+HS++IIHRDLKPSN+AVNEDCELKILDFGLAR TD+EMTGYVATRWYRAPEIML+WMHY VDIWSVGCIMAEL T + LFPG DHI+QL++IM L GTP +N++ S +AR +I+ Q P+ +F + F + A+DLL++MLVLD D+RI+A ALAH Y A YHD DEP A + E + D+ ++ WK +D + +F P
Sbjct: 18 WEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPAYLINRMPSHEARNYIQSLTQM-PKMNFANVF--IGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESR-DLLIDEWKSLTYDEVISFVP 350
BLAST of Mitogen-activated protein kinase vs. Ensembl Human
Match: MAPK12 (mitogen-activated protein kinase 12 [Source:HGNC Symbol;Acc:HGNC:6874]) HSP 1 Score: 378.637 bits (971), Expect = 6.541e-123 Identity = 174/347 (50.14%), Postives = 243/347 (70.03%), Query Frame = 1
Query: 1546 FQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTP 2586
F + + W V Y +L P+G GAYG+VC+A D + +VAIKKL RPF S +AKR YREL+++ HM HEN++ L+D +TP T + F+D YL+ P MG DL +++ ++L + +QFLVYQ+L+GL+Y+H++ IIHRDLKP N+AVNEDCELKILDFGLARQ D EMTGYV TRWYRAPE++L+WM YT VDIWSVGCIMAE+ T K LF G+DH+DQLK+IM++ GTP EF+ ++ S++A+ +++ + +KDF S + A++LL++MLVLD ++R++A +ALAHPY HD DEP + D + D L+ WK + + +F P
Sbjct: 11 FYRQEVTKTAWEVRAVYRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMKHEKLGEDRIQFLVYQMLKGLRYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADSEMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMKVTGTPPAEFVQRLQSDEAKNYMK-GLPELEKKDFASILTNASP--LAVNLLEKMLVLDAEQRVTAGEALAHPYFESLHDTEDEPQVQKYDDSFD-DVDRTLDEWKRVTYKEVLSFKP 353
BLAST of Mitogen-activated protein kinase vs. Ensembl Celegans
Match: pmk-1 (Mitogen-activated protein kinase pmk-1 [Source:UniProtKB/Swiss-Prot;Acc:Q17446]) HSP 1 Score: 414.846 bits (1065), Expect = 3.487e-137 Identity = 207/345 (60.00%), Postives = 254/345 (73.62%), Query Frame = 1
Query: 1570 SDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLET---WKDTVWDFIQNFTPRIS 2595
S W VP Y NL PIG GAYG+VCAA + +VAIKK RPF S +A+RTYREL+++ M HENI+ L+D +TP DVY ++ LMGADL+ I++ Q L ++H+QFLVYQILRGLKY+HS++IIHRDLKPSNIAVNEDCELKILDFGLARQTD EMTGYVATRWYRAPEIML+WMHYT VD+WSVGCI+AEL T K LFPG+DHIDQL +IM + GTPD+EF+ KI SE+AR +IR + R+DF F Q T AIDLL++ML LDPDRR +AK+A+ H YLA YHDE DEP A + M+ DV +T WK +W+ I +F ++
Sbjct: 27 SVWVVPNYYINLTPIGTGAYGTVCAAECTRSGTRVAIKKFNRPFQSIIHARRTYRELRLLRCMCHENIIDLLDVFTPNENVNDIEDVYFVSMLMGADLSNILKIQRLNDDHIQFLVYQILRGLKYIHSADIIHRDLKPSNIAVNEDCELKILDFGLARQTDSEMTGYVATRWYRAPEIMLNWMHYTQTVDVWSVGCILAELITGKTLFPGSDHIDQLTRIMSVTGTPDEEFLKKISSEEARNYIR-NLPKMTRRDFKRLFAQATP--QAIDLLEKMLHLDPDRRPTAKEAMEHEYLAAYHDETDEPIA----EEMDLNDDVRADTIDEWKKIIWEEISDFQKNVA 364
BLAST of Mitogen-activated protein kinase vs. Ensembl Celegans
Match: pmk-2 (Mitogen-activated protein kinase pmk-2 [Source:UniProtKB/Swiss-Prot;Acc:Q8MXI4]) HSP 1 Score: 358.992 bits (920), Expect = 2.334e-115 Identity = 184/341 (53.96%), Postives = 242/341 (70.97%), Query Frame = 1
Query: 1570 SDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSP--RKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTA--PLFVDVMEGKTDVDLETWKDTVWDFIQNF 2580
+ W +P Y +L P+G GAYG VC A +VAIKK RPF S +AKRTYRELK++ + H+N++ +ID +TP S ++VY ++ LMG+DL I++ Q L +E +Q L+YQ+LRGLKY+HS+ IIHRDLKPSNIAVNE CE+KILDFGLAR D EMTGYVATRWYRAPEIML+WMHYT VD+WSVGCI+AEL + +PLFPG+DHIDQL KIM + GTP +EF +KI SE+AR +I+ + SP R+DF + F + A++LL+ ML+LDPDRRIS AL H YL +Y +DEP A + +D E + L W++ +W+ I+ F
Sbjct: 41 TKWVLPQWYNSLKPLGEGAYGVVCTAEYEPTGDRVAIKKFFRPFQSTIHAKRTYRELKLLRTLQHDNVLEMIDVFTPDPDASSLNNVYFVSVLMGSDLQNIMKIQRLTDEQIQLLIYQVLRGLKYIHSAGIIHRDLKPSNIAVNERCEVKILDFGLARAQDAEMTGYVATRWYRAPEIMLNWMHYTQTVDVWSVGCILAELVSGRPLFPGDDHIDQLTKIMSVVGTPKEEFWSKIQSEEARNYIKNR---SPIIRQDFVTLFPMASP--YALELLEMMLILDPDRRISVSSALRHDYLREYSVPNDEPVAMDTVTIDPAEERA-TTLSDWRELIWNEIRLF 375
BLAST of Mitogen-activated protein kinase vs. Ensembl Celegans
Match: pmk-2 (Mitogen-activated protein kinase pmk-2 [Source:UniProtKB/Swiss-Prot;Acc:Q8MXI4]) HSP 1 Score: 356.681 bits (914), Expect = 2.101e-114 Identity = 184/346 (53.18%), Postives = 242/346 (69.94%), Query Frame = 1
Query: 1570 SDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSP--RKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAP-------LFVDVMEGKTDVDLETWKDTVWDFIQNF 2580
+ W +P Y +L P+G GAYG VC A +VAIKK RPF S +AKRTYRELK++ + H+N++ +ID +TP S ++VY ++ LMG+DL I++ Q L +E +Q L+YQ+LRGLKY+HS+ IIHRDLKPSNIAVNE CE+KILDFGLAR D EMTGYVATRWYRAPEIML+WMHYT VD+WSVGCI+AEL + +PLFPG+DHIDQL KIM + GTP +EF +KI SE+AR +I+ + SP R+DF + F + A++LL+ ML+LDPDRRIS AL H YL +Y +DEP A + +D E + L W++ +W+ I+ F
Sbjct: 41 TKWVLPQWYNSLKPLGEGAYGVVCTAEYEPTGDRVAIKKFFRPFQSTIHAKRTYRELKLLRTLQHDNVLEMIDVFTPDPDASSLNNVYFVSVLMGSDLQNIMKIQRLTDEQIQLLIYQVLRGLKYIHSAGIIHRDLKPSNIAVNERCEVKILDFGLARAQDAEMTGYVATRWYRAPEIMLNWMHYTQTVDVWSVGCILAELVSGRPLFPGDDHIDQLTKIMSVVGTPKEEFWSKIQSEEARNYIKNR---SPIIRQDFVTLFPMASP--YALELLEMMLILDPDRRISVSSALRHDYLREYSVPNDEPVAMDTVINSIVTIDPAEERA-TTLSDWRELIWNEIRLF 380
BLAST of Mitogen-activated protein kinase vs. Ensembl Celegans
Match: jnk-1 (Stress-activated protein kinase jnk-1 [Source:UniProtKB/Swiss-Prot;Acc:Q8WQG9]) HSP 1 Score: 286.189 bits (731), Expect = 3.306e-88 Identity = 152/346 (43.93%), Postives = 221/346 (63.87%), Query Frame = 1
Query: 1558 NIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEE--MTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFI--REKIQTSPRKD-FNSFFWQYTKDEN------AIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVW 2562
I + V RY+NL IG GA G VC+AFD QVAIKKL+RPF + +AKR YRELK++ ++H+NI+ +++ +TPQ + F+D+Y++ LM A+L +I+ +L +E + +L+YQ+L G++++HS+ IIHRDLKPSNI V DC LKILDFGLAR E MT YV TR+YRAPE++L M Y VD+WS+GCI EL + LFPG DHIDQ +I+E GTPD+ F+ ++ R ++ R + Q +P + F+ + T D + A DLL RMLV+DP+RRIS DAL HPY+ + DE + P + ++++W++ ++
Sbjct: 16 TIGEAQMVVLKRYQNLRLIGSGAQGIVCSAFDTVRNEQVAIKKLSRPFQNVTHAKRAYRELKLMSLVNHKNIIGILNCFTPQKKLDEFNDLYIVMELMDANLCQVIQ-MDLDHERLSYLLYQMLCGIRHLHSAGIIHRDLKPSNIVVRSDCTLKILDFGLARTAIEAFMMTPYVVTRYYRAPEVILG-MGYKENVDVWSIGCIFGELIRGRVLFPGGDHIDQWTRIIEQLGTPDRSFLERL-QPTVRNYVENRPRYQATPFEVLFSDNMFPMTADSSRLTGAQARDLLSRMLVIDPERRISVDDALRHPYVNVWFDEIEVYAPPPLPYDHNMDVEQNVDSWREHIF 358
BLAST of Mitogen-activated protein kinase vs. Ensembl Celegans
Match: jnk-1 (Stress-activated protein kinase jnk-1 [Source:UniProtKB/Swiss-Prot;Acc:Q8WQG9]) HSP 1 Score: 286.189 bits (731), Expect = 3.306e-88 Identity = 152/346 (43.93%), Postives = 221/346 (63.87%), Query Frame = 1
Query: 1558 NIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEE--MTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFI--REKIQTSPRKD-FNSFFWQYTKDEN------AIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVW 2562
I + V RY+NL IG GA G VC+AFD QVAIKKL+RPF + +AKR YRELK++ ++H+NI+ +++ +TPQ + F+D+Y++ LM A+L +I+ +L +E + +L+YQ+L G++++HS+ IIHRDLKPSNI V DC LKILDFGLAR E MT YV TR+YRAPE++L M Y VD+WS+GCI EL + LFPG DHIDQ +I+E GTPD+ F+ ++ R ++ R + Q +P + F+ + T D + A DLL RMLV+DP+RRIS DAL HPY+ + DE + P + ++++W++ ++
Sbjct: 16 TIGEAQMVVLKRYQNLRLIGSGAQGIVCSAFDTVRNEQVAIKKLSRPFQNVTHAKRAYRELKLMSLVNHKNIIGILNCFTPQKKLDEFNDLYIVMELMDANLCQVIQ-MDLDHERLSYLLYQMLCGIRHLHSAGIIHRDLKPSNIVVRSDCTLKILDFGLARTAIEAFMMTPYVVTRYYRAPEVILG-MGYKENVDVWSIGCIFGELIRGRVLFPGGDHIDQWTRIIEQLGTPDRSFLERL-QPTVRNYVENRPRYQATPFEVLFSDNMFPMTADSSRLTGAQARDLLSRMLVIDPERRISVDDALRHPYVNVWFDEIEVYAPPPLPYDHNMDVEQNVDSWREHIF 358
BLAST of Mitogen-activated protein kinase vs. Ensembl Fly
Match: p38b (gene:FBgn0024846 transcript:FBtr0080534) HSP 1 Score: 413.305 bits (1061), Expect = 1.268e-136 Identity = 202/352 (57.39%), Postives = 254/352 (72.16%), Query Frame = 1
Query: 1540 AEFQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRES---FSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTP 2586
A+F +I ++W +P Y+NL P+G GAYG VC A +VAIKKLARPF S +AKRTYREL+++ HMDHEN++ L+D + P +S F VY++T LM ADLN IIRTQ+L ++HVQFLVYQILRGLKY+HS+ +IHRDLKPSNIAVNEDCEL+ILDFGLAR + EMTGYVATRWYRAPEIML+WMHY DIWSVGCIMAEL T + LFPG DHI QL IME+ GTP EFM++I SE AR +IR + PR++F F + AIDLL++ML LD D+RI+A+ ALAHPY+ YHD DE TA L+ E + ++ +E W++ V+ + F P
Sbjct: 6 AKFYKLDINRTEWEIPETYQNLQPVGQGAYGQVCKAVVRGTSTKVAIKKLARPFQSAVHAKRTYRELRLLKHMDHENVIGLLDVFHPGQPADSLDQFQQVYMVTHLMDADLNNIIRTQKLSDDHVQFLVYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARPAESEMTGYVATRWYRAPEIMLNWMHYNQTADIWSVGCIMAELLTGRTLFPGTDHIHQLNLIMEVLGTPADEFMSRISSESARNYIR-SLPVMPRRNFRDIF--RGANPLAIDLLEKMLELDADKRITAEQALAHPYMEKYHDPTDEQTAALYDQSFE-ENELPVEKWREMVFSEVTAFKP 353
BLAST of Mitogen-activated protein kinase vs. Ensembl Fly
Match: p38a (gene:FBgn0015765 transcript:FBtr0084580) HSP 1 Score: 394.045 bits (1011), Expect = 4.054e-129 Identity = 198/357 (55.46%), Postives = 252/357 (70.59%), Query Frame = 1
Query: 1531 NMAAEFQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQ---STRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDEN--AIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTP 2586
++ +F +I ++W +P Y++L P+G GAYG V A VAIKKLARPF S +AKRTYREL+++ HMDHEN++ L+D + P + E+F VYL+T LM ADLN IIR Q L ++HVQFLVYQILRGLKY+HS+ +IHRDLKPSNIAVNEDCEL+ILDFGLAR T+ EMTGYVATRWYRAPEIML+WMHY VDIWSVGCIMAEL TR+ LFPG DHI QL IME+ GTP EF+ KI SE AR++I+ R N F K+ N AIDLL++ML LD ++RI+A++AL+HPYL Y + E T+P + E D+ ++ WK+ ++ + NF P
Sbjct: 4 SITKKFYKLDINRTEWEIPDIYQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVHAKRTYRELRLLKHMDHENVIGLLDIFHPHPANGSLENFQQVYLVTHLMDADLNNIIRMQHLSDDHVQFLVYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARPTENEMTGYVATRWYRAPEIMLNWMHYDQTVDIWSVGCIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPAEFLKKISSESARSYIQSLPPMKGRSFKNVF-----KNANPLAIDLLEKMLELDAEKRITAEEALSHPYLEKYAEPSVEQTSPPYDHSFE-DMDLPVDKWKELIYKEVTNFKP 354
BLAST of Mitogen-activated protein kinase vs. Ensembl Fly
Match: p38a (gene:FBgn0015765 transcript:FBtr0300572) HSP 1 Score: 394.045 bits (1011), Expect = 4.054e-129 Identity = 198/357 (55.46%), Postives = 252/357 (70.59%), Query Frame = 1
Query: 1531 NMAAEFQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQ---STRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDEN--AIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTP 2586
++ +F +I ++W +P Y++L P+G GAYG V A VAIKKLARPF S +AKRTYREL+++ HMDHEN++ L+D + P + E+F VYL+T LM ADLN IIR Q L ++HVQFLVYQILRGLKY+HS+ +IHRDLKPSNIAVNEDCEL+ILDFGLAR T+ EMTGYVATRWYRAPEIML+WMHY VDIWSVGCIMAEL TR+ LFPG DHI QL IME+ GTP EF+ KI SE AR++I+ R N F K+ N AIDLL++ML LD ++RI+A++AL+HPYL Y + E T+P + E D+ ++ WK+ ++ + NF P
Sbjct: 4 SITKKFYKLDINRTEWEIPDIYQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVHAKRTYRELRLLKHMDHENVIGLLDIFHPHPANGSLENFQQVYLVTHLMDADLNNIIRMQHLSDDHVQFLVYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARPTENEMTGYVATRWYRAPEIMLNWMHYDQTVDIWSVGCIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPAEFLKKISSESARSYIQSLPPMKGRSFKNVF-----KNANPLAIDLLEKMLELDAEKRITAEEALSHPYLEKYAEPSVEQTSPPYDHSFE-DMDLPVDKWKELIYKEVTNFKP 354
BLAST of Mitogen-activated protein kinase vs. Ensembl Fly
Match: p38a (gene:FBgn0015765 transcript:FBtr0084581) HSP 1 Score: 394.045 bits (1011), Expect = 4.054e-129 Identity = 198/357 (55.46%), Postives = 252/357 (70.59%), Query Frame = 1
Query: 1531 NMAAEFQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQ---STRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDEN--AIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTP 2586
++ +F +I ++W +P Y++L P+G GAYG V A VAIKKLARPF S +AKRTYREL+++ HMDHEN++ L+D + P + E+F VYL+T LM ADLN IIR Q L ++HVQFLVYQILRGLKY+HS+ +IHRDLKPSNIAVNEDCEL+ILDFGLAR T+ EMTGYVATRWYRAPEIML+WMHY VDIWSVGCIMAEL TR+ LFPG DHI QL IME+ GTP EF+ KI SE AR++I+ R N F K+ N AIDLL++ML LD ++RI+A++AL+HPYL Y + E T+P + E D+ ++ WK+ ++ + NF P
Sbjct: 4 SITKKFYKLDINRTEWEIPDIYQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVHAKRTYRELRLLKHMDHENVIGLLDIFHPHPANGSLENFQQVYLVTHLMDADLNNIIRMQHLSDDHVQFLVYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARPTENEMTGYVATRWYRAPEIMLNWMHYDQTVDIWSVGCIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPAEFLKKISSESARSYIQSLPPMKGRSFKNVF-----KNANPLAIDLLEKMLELDAEKRITAEEALSHPYLEKYAEPSVEQTSPPYDHSFE-DMDLPVDKWKELIYKEVTNFKP 354
BLAST of Mitogen-activated protein kinase vs. Ensembl Fly
Match: bsk (gene:FBgn0000229 transcript:FBtr0300982) HSP 1 Score: 291.582 bits (745), Expect = 4.105e-90 Identity = 160/358 (44.69%), Postives = 227/358 (63.41%), Query Frame = 1
Query: 1561 IAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQ--TDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQY--------------TKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHD--EHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNF 2580
+ +++T+ +RY NL PIG GA G VCAA+D Q+ VAIKKL+RPF + +AKR YRE K++ ++H+NI+ L++A+TPQ E F DVYL+ LM A+L +I+ +L ++ + +L+YQ+L G+K++HS+ IIHRDLKPSNI V DC LKILDFGLAR T MT YV TR+YRAPE++L M YT VDIWSVGCIM E+ LFPG DHIDQ KI+E GTP FM ++ + +R ++ PR SF + K +A +LL +MLV+DP++RIS +AL H Y+ ++D E D P AP D + + +E WK+ +++ + ++
Sbjct: 13 VGDTNFTIHSRYINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQNVTHAKRAYREFKLMKLVNHKNIIGLLNAFTPQRNLEEFQDVYLVMELMDANLCQVIQ-MDLDHDRMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLARTAGTTFMMTPYVVTRYYRAPEVILG-MGYTENVDIWSVGCIMGEMIRGGVLFPGTDHIDQWNKIIEQLGTPSPSFMQRL-----QPTVRNYVENRPRYTGYSFDRLFPDGLFPNDNNQNSRRKASDARNLLSKMLVIDPEQRISVDEALKHEYINVWYDAEEVDAP-APEPYDHSVDEREHTVEQWKELIYEEVMDY 362
BLAST of Mitogen-activated protein kinase vs. Ensembl Zebrafish
Match: mapk14a (mitogen-activated protein kinase 14a [Source:NCBI gene;Acc:65237]) HSP 1 Score: 431.024 bits (1107), Expect = 1.990e-143 Identity = 206/349 (59.03%), Postives = 263/349 (75.36%), Query Frame = 1
Query: 1546 FQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTPRI 2592
F + + W VP +Y+NL+P+G GAYGSVC+AFD K +VA+KKL+RPF S +AKRTYREL+++ HM HEN++ L+D +TP ++ + F+DVYL+T LMGADLN I++ Q+L ++HVQFL+YQILRGLKY+HS++IIHRDLKPSN+AVNEDCELKILDFGLAR TD+EMTGYVATRWYRAPEIML+WMHY VDIWSVGCIMAEL T + LFPG DHIDQLK IM L GTP + KI SE AR +I Q P+++F F + A+DLL++MLVLD D+RI+A +ALAHPY A YHD DEP A F E + ++D+E WK ++ + +F P +
Sbjct: 9 FYRQEVNKTIWEVPVQYQNLSPVGSGAYGSVCSAFDAKTGFKVAVKKLSRPFQSIIHAKRTYRELRLLKHMRHENVIGLLDVFTPATSLKEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNVTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLIMLLVGTPGPGLLMKISSESARTYISSLPQM-PKRNFADVF--IGANPQAVDLLEKMLVLDTDKRITAAEALAHPYFAQYHDPDDEPEAEPFDQSFESR-ELDIEEWKRQTYEEMISFEPPV 353
BLAST of Mitogen-activated protein kinase vs. Ensembl Zebrafish
Match: mapk14a (mitogen-activated protein kinase 14a [Source:NCBI gene;Acc:65237]) HSP 1 Score: 431.024 bits (1107), Expect = 1.990e-143 Identity = 206/349 (59.03%), Postives = 263/349 (75.36%), Query Frame = 1
Query: 1546 FQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTPRI 2592
F + + W VP +Y+NL+P+G GAYGSVC+AFD K +VA+KKL+RPF S +AKRTYREL+++ HM HEN++ L+D +TP ++ + F+DVYL+T LMGADLN I++ Q+L ++HVQFL+YQILRGLKY+HS++IIHRDLKPSN+AVNEDCELKILDFGLAR TD+EMTGYVATRWYRAPEIML+WMHY VDIWSVGCIMAEL T + LFPG DHIDQLK IM L GTP + KI SE AR +I Q P+++F F + A+DLL++MLVLD D+RI+A +ALAHPY A YHD DEP A F E + ++D+E WK ++ + +F P +
Sbjct: 9 FYRQEVNKTIWEVPVQYQNLSPVGSGAYGSVCSAFDAKTGFKVAVKKLSRPFQSIIHAKRTYRELRLLKHMRHENVIGLLDVFTPATSLKEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNVTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLIMLLVGTPGPGLLMKISSESARTYISSLPQM-PKRNFADVF--IGANPQAVDLLEKMLVLDTDKRITAAEALAHPYFAQYHDPDDEPEAEPFDQSFESR-ELDIEEWKRQTYEEMISFEPPV 353
BLAST of Mitogen-activated protein kinase vs. Ensembl Zebrafish
Match: mapk14b (mitogen-activated protein kinase 14b [Source:NCBI gene;Acc:266756]) HSP 1 Score: 430.254 bits (1105), Expect = 4.644e-143 Identity = 205/349 (58.74%), Postives = 262/349 (75.07%), Query Frame = 1
Query: 1546 FQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTPRI 2592
F + + W VP RY+NL+P+G GAYGSVC+AFD K +VA+KKL+RPF S +AKRTYREL+++ HM HEN++ L+D ++P ++ E F+DVYL+T LMGADLN I++ Q+L ++HVQFL+YQILR LKY+HS++IIHRDLKPSN+AVNEDCELKILDFGLAR TD+EMTGYVATRWYRAPEIML+WMHY VDIWSVGCIMAEL T + LFPG DHIDQLK IM L GTP E + KI SE AR +I + P+++F F + A+DLL++MLVLD D+RI+A ALAHPY A YHD DEP A + E + D+++E WK ++ + +F P +
Sbjct: 9 FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCSAFDGKAGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFSPATSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRALKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARLTDDEMTGYVATRWYRAPEIMLNWMHYNMTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLIMMLVGTPGPELLMKISSESARNYI-SSLPHMPKRNFADVF--IGANPLAVDLLEKMLVLDTDKRITASQALAHPYFAQYHDPDDEPEADPYDQSFESR-DLEIEEWKSLTYEEVMSFEPPV 353
BLAST of Mitogen-activated protein kinase vs. Ensembl Zebrafish
Match: mapk11 (mitogen-activated protein kinase 11 [Source:ZFIN;Acc:ZDB-GENE-040625-75]) HSP 1 Score: 429.483 bits (1103), Expect = 8.465e-143 Identity = 201/345 (58.26%), Postives = 262/345 (75.94%), Query Frame = 1
Query: 1546 FQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNF 2580
F + + W VP RY+NL P+G GAYGSVC+A+D +L+++VA+KKL+RPF S +++RTYREL+++ HM HEN++ L+D +TP ++ E F++VYL+T LMGADLN I++ Q L +EHVQFL+YQ+LRGLKY+HS+ +IHRDLKPSN+AVNEDCEL+ILDFGLARQTD+EMTGYVATRWYRAPEIML+WMHY VDIWSVGCIM EL K LFPGND+IDQLK+IME+ GTP + + KI SE A+ +I + + P++D F + A+DLL +MLVLD D RISA +AL HPY + YHD DEP AP + E K D +E WK+ V++ + NF
Sbjct: 7 FYRQELNKTVWEVPERYQNLTPVGSGAYGSVCSAYDVRLRQKVAVKKLSRPFQSLIHSRRTYRELRLLKHMKHENVIGLLDVFTPAASLEEFNEVYLVTNLMGADLNNIVKFQRLSDEHVQFLIYQLLRGLKYIHSAGLIHRDLKPSNVAVNEDCELRILDFGLARQTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMGELLKGKVLFPGNDYIDQLKRIMEVVGTPTPDVLKKISSEHAQKYI-QSLPHMPQQDLGKIF--RGANPLAVDLLKKMLVLDCDGRISASEALCHPYFSQYHDPEDEPEAPPYDQTPESK-DRTMEEWKELVFEEVSNF 347
BLAST of Mitogen-activated protein kinase vs. Ensembl Zebrafish
Match: mapk14a (mitogen-activated protein kinase 14a [Source:NCBI gene;Acc:65237]) HSP 1 Score: 427.557 bits (1098), Expect = 5.238e-142 Identity = 201/349 (57.59%), Postives = 265/349 (75.93%), Query Frame = 1
Query: 1546 FQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTPRI 2592
F + + W VP +Y+NL+P+G GAYGSVC+AFD K +VA+KKL+RPF S +AKRTYREL+++ HM HEN++ L+D +TP ++ + F+DVYL+T LMGADLN I++ Q+L ++HVQFL+YQILRGLKY+HS++IIHRDLKPSN+AVNEDCELKILDFGLAR TD+EMTGYVATRWYRAPEIML+WMHY VDIWSVGCIMAEL T + LFPG DHI+QL++IM L GTP ++++ S +AR +I Q P+++F F + A+DLL++MLVLD D+RI+A +ALAHPY A YHD DEP A F E + ++D+E WK ++ + +F P +
Sbjct: 9 FYRQEVNKTIWEVPVQYQNLSPVGSGAYGSVCSAFDAKTGFKVAVKKLSRPFQSIIHAKRTYRELRLLKHMRHENVIGLLDVFTPATSLKEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNVTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPSSLISRMPSHEARTYISSLPQM-PKRNFADVF--IGANPQAVDLLEKMLVLDTDKRITAAEALAHPYFAQYHDPDDEPEAEPFDQSFESR-ELDIEEWKRQTYEEMISFEPPV 353
BLAST of Mitogen-activated protein kinase vs. Ensembl Xenopus
Match: pde6a (phosphodiesterase 6A [Source:Xenbase;Acc:XB-GENE-988755]) HSP 1 Score: 434.876 bits (1117), Expect = 1.031e-144 Identity = 207/352 (58.81%), Postives = 263/352 (74.72%), Query Frame = 1
Query: 1531 NMAAEFQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTP 2586
N + F + + W VP RY+NL P+G GAYGSVC+AFD + + +VA+KKL+RPF S +AKRTYREL+++ HM HEN++ L+D +TP + E F+DVYL+T LMGADLN I++ Q+L ++HVQFL+YQILRGLKY+HS+ IIHRDLKPSN+AVNEDCELKILDFGLAR TDEEMTGYVATRWYRAPEIML+WMHY VDIWSVGCIMAEL T + LFPG DHIDQLK I+ L GTP+ E + KI SE AR +I + + P+ +F F + A+DLL++MLVLD D+RI+A +ALAHPY A YHD DEP A + E + ++D+E WK ++ + F P
Sbjct: 4 NQSYVFYRQELNKTLWEVPDRYQNLTPVGSGAYGSVCSAFDTRTELRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPAKSFEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHTDEEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPEPELLQKISSEAARNYI-QSLPYMPKMNFEDVFL--GANPQAVDLLEKMLVLDTDKRITAAEALAHPYFAQYHDPDDEPIAEPYDQSFESR-ELDIEEWKRLTYEEVICFVP 351
BLAST of Mitogen-activated protein kinase vs. Ensembl Xenopus
Match: pde6a (phosphodiesterase 6A [Source:Xenbase;Acc:XB-GENE-988755]) HSP 1 Score: 429.098 bits (1102), Expect = 1.417e-142 Identity = 203/352 (57.67%), Postives = 263/352 (74.72%), Query Frame = 1
Query: 1531 NMAAEFQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTP 2586
N + F + + W VP RY+NL P+G GAYGSVC+AFD + + +VA+KKL+RPF S +AKRTYREL+++ HM HEN++ L+D +TP + E F+DVYL+T LMGADLN I++ Q+L ++HVQFL+YQILRGLKY+HS+ IIHRDLKPSN+AVNEDCELKILDFGLAR TDEEMTGYVATRWYRAPEIML+WMHY VDIWSVGCIMAEL T + LFPG DHI+QL++IM L GTP +N++ S +AR +I + + P+ +F F + A+DLL++MLVLD D+RI+A +ALAHPY A YHD DEP A + E + ++D+E WK ++ + F P
Sbjct: 4 NQSYVFYRQELNKTLWEVPDRYQNLTPVGSGAYGSVCSAFDTRTELRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPAKSFEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHTDEEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPSYLINRMPSHEARNYI-QSLPYMPKMNFEDVFL--GANPQAVDLLEKMLVLDTDKRITAAEALAHPYFAQYHDPDDEPIAEPYDQSFESR-ELDIEEWKRLTYEEVICFVP 351
BLAST of Mitogen-activated protein kinase vs. Ensembl Xenopus
Match: mapk11 (mitogen-activated protein kinase 11 [Source:NCBI gene;Acc:100101766]) HSP 1 Score: 427.557 bits (1098), Expect = 5.649e-142 Identity = 198/345 (57.39%), Postives = 266/345 (77.10%), Query Frame = 1
Query: 1546 FQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNF 2580
F + + W VP RY+ L P+G GA+GSVC+A+D K +++VA+KKL+RPF S +A+RTYREL+++ HM HEN++ L+D +TP ++ E+F++VYL+T LMGADLN I++ Q+L ++H+QFL+YQ+LRGLKY+HS+ IIHRDLKPSN+AVNEDCEL+ILDFGLARQ D+EMTGYVATRWYRAPEIML+WMHY VDIWSVGCIMAEL K LFPGND+IDQLK+IME+ GTP+ EF+ KI SE AR +I E + P++D F + + AIDLL++ML+LD D+RI+A +ALAHPY YHD DEP A + + E K + ++ WK+ ++ + +F
Sbjct: 7 FYKQELNKTVWEVPDRYQRLTPVGSGAFGSVCSAYDTKTRQKVAVKKLSRPFQSLVHARRTYRELRLLKHMKHENVIGLLDVFTPSTSGENFNEVYLVTNLMGADLNNIVKCQKLTDDHIQFLIYQLLRGLKYIHSAGIIHRDLKPSNLAVNEDCELRILDFGLARQADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLKGKALFPGNDYIDQLKRIMEVVGTPNSEFLLKISSEHARRYI-ESLPYMPQQDLKEVF--HGANPLAIDLLEKMLILDSDKRITATEALAHPYFVQYHDPDDEPEAEPYDESTENK-ERTIDEWKEITYEEVISF 347
BLAST of Mitogen-activated protein kinase vs. Ensembl Xenopus
Match: mapk11 (mitogen-activated protein kinase 11 [Source:NCBI gene;Acc:100101766]) HSP 1 Score: 413.305 bits (1061), Expect = 3.466e-136 Identity = 194/338 (57.40%), Postives = 252/338 (74.56%), Query Frame = 1
Query: 1546 FQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTV 2559
F + + W VP RY+ L P+G GA+GSVC+A+D K +++VA+KKL+RPF S +A+RTYREL+++ HM HEN++ L+D +TP ++ E+F++VYL+T LMGADLN I++ Q+L ++H+QFL+YQ+LRGLKY+HS+ IIHRDLKPSN+AVNEDCEL+ILDFGLARQ D+EMTGYVATRWYRAPEIML+WMHY VDIWSVGCIMAEL K LFPGND+IDQLK+IME+ GTP+ EF+ KI SE F SF + AIDLL++ML+LD D+RI+A +ALAHPY YHD DEP A + + E K + ++ WK V
Sbjct: 9 FYKQELNKTVWEVPDRYQRLTPVGSGAFGSVCSAYDTKTRQKVAVKKLSRPFQSLVHARRTYRELRLLKHMKHENVIGLLDVFTPSTSGENFNEVYLVTNLMGADLNNIVKCQKLTDDHIQFLIYQLLRGLKYIHSAGIIHRDLKPSNLAVNEDCELRILDFGLARQADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLKGKALFPGNDYIDQLKRIMEVVGTPNSEFLLKISSEHVSRF--------------SFLLK------AIDLLEKMLILDSDKRITATEALAHPYFVQYHDPDDEPEAEPYDESTENK-ERTIDEWKGKV 325
BLAST of Mitogen-activated protein kinase vs. Ensembl Xenopus
Match: mapk11 (mitogen-activated protein kinase 11 [Source:NCBI gene;Acc:100101766]) HSP 1 Score: 413.305 bits (1061), Expect = 3.923e-136 Identity = 194/338 (57.40%), Postives = 252/338 (74.56%), Query Frame = 1
Query: 1546 FQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTV 2559
F + + W VP RY+ L P+G GA+GSVC+A+D K +++VA+KKL+RPF S +A+RTYREL+++ HM HEN++ L+D +TP ++ E+F++VYL+T LMGADLN I++ Q+L ++H+QFL+YQ+LRGLKY+HS+ IIHRDLKPSN+AVNEDCEL+ILDFGLARQ D+EMTGYVATRWYRAPEIML+WMHY VDIWSVGCIMAEL K LFPGND+IDQLK+IME+ GTP+ EF+ KI SE F SF + AIDLL++ML+LD D+RI+A +ALAHPY YHD DEP A + + E K + ++ WK V
Sbjct: 7 FYKQELNKTVWEVPDRYQRLTPVGSGAFGSVCSAYDTKTRQKVAVKKLSRPFQSLVHARRTYRELRLLKHMKHENVIGLLDVFTPSTSGENFNEVYLVTNLMGADLNNIVKCQKLTDDHIQFLIYQLLRGLKYIHSAGIIHRDLKPSNLAVNEDCELRILDFGLARQADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLKGKALFPGNDYIDQLKRIMEVVGTPNSEFLLKISSEHVSRF--------------SFLLK------AIDLLEKMLILDSDKRITATEALAHPYFVQYHDPDDEPEAEPYDESTENK-ERTIDEWKGKV 323
BLAST of Mitogen-activated protein kinase vs. Ensembl Mouse
Match: Mapk11 (mitogen-activated protein kinase 11 [Source:MGI Symbol;Acc:MGI:1338024]) HSP 1 Score: 436.802 bits (1122), Expect = 1.340e-145 Identity = 207/349 (59.31%), Postives = 265/349 (75.93%), Query Frame = 1
Query: 1540 AEFQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTP 2586
A F + + W VP R + L P+G GAYGSVC+A+D +L+++VA+KKL+RPF S +A+RTYREL+++ H+ HEN++ L+D +TP ++ E FS+VYL+T LMGADLN I++ Q L +EHVQFLVYQ+LRGLKY+HS+ IIHRDLKPSN+AVNEDCEL+ILDFGLARQ DEEMTGYVATRWYRAPEIML+WMHY VDIWSVGCIMAEL K LFPGND+IDQLK+IME+ GTP E + KI SE AR +I + + P+KD +S F + + AIDLL RMLVLD D+R+SA +ALAH Y + YHD DEP A + + +E K + LE WK+ + + +F P
Sbjct: 6 AGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGNDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYI-QSLPPMPQKDLSSVF--HGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPDDEPEAEPYDESVEAK-ERTLEEWKELTYQEVLSFKP 350
BLAST of Mitogen-activated protein kinase vs. Ensembl Mouse
Match: Mapk14 (mitogen-activated protein kinase 14 [Source:MGI Symbol;Acc:MGI:1346865]) HSP 1 Score: 433.335 bits (1113), Expect = 3.009e-144 Identity = 206/337 (61.13%), Postives = 257/337 (76.26%), Query Frame = 1
Query: 1576 WTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTP 2586
W VP RY+NL+P+G GAYGSVCAAFD K +VA+KKL+RPF S +AKRTYREL+++ HM HEN++ L+D +TP + E F+DVYL+T LMGADLN I++ Q+L ++HVQFL+YQILRGLKY+HS++IIHRDLKPSN+AVNEDCELKILDFGLAR TD+EMTGYVATRWYRAPEIML+WMHY VDIWSVGCIMAEL T + LFPG DHIDQLK I+ L GTP E + KI SE AR +I+ Q P+ +F + F + A+DLL++MLVLD D+RI+A ALAH Y A YHD DEP A + E + D+ ++ WK +D + +F P
Sbjct: 18 WEVPERYQNLSPVGSGAYGSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLAQM-PKMNFANVF--IGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESR-DLLIDEWKSLTYDEVISFVP 350
BLAST of Mitogen-activated protein kinase vs. Ensembl Mouse
Match: Mapk14 (mitogen-activated protein kinase 14 [Source:MGI Symbol;Acc:MGI:1346865]) HSP 1 Score: 426.402 bits (1095), Expect = 1.402e-141 Identity = 202/337 (59.94%), Postives = 258/337 (76.56%), Query Frame = 1
Query: 1576 WTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTP 2586
W VP RY+NL+P+G GAYGSVCAAFD K +VA+KKL+RPF S +AKRTYREL+++ HM HEN++ L+D +TP + E F+DVYL+T LMGADLN I++ Q+L ++HVQFL+YQILRGLKY+HS++IIHRDLKPSN+AVNEDCELKILDFGLAR TD+EMTGYVATRWYRAPEIML+WMHY VDIWSVGCIMAEL T + LFPG DHI+QL++IM L GTP +N++ S +AR +I+ Q P+ +F + F + A+DLL++MLVLD D+RI+A ALAH Y A YHD DEP A + E + D+ ++ WK +D + +F P
Sbjct: 18 WEVPERYQNLSPVGSGAYGSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPAYLINRMPSHEARNYIQSLAQM-PKMNFANVF--IGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESR-DLLIDEWKSLTYDEVISFVP 350
BLAST of Mitogen-activated protein kinase vs. Ensembl Mouse
Match: Mapk12 (mitogen-activated protein kinase 12 [Source:MGI Symbol;Acc:MGI:1353438]) HSP 1 Score: 382.874 bits (982), Expect = 1.003e-124 Identity = 179/349 (51.29%), Postives = 243/349 (69.63%), Query Frame = 1
Query: 1546 FQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVD--LETWKDTVWDFIQNFTP 2586
F + + W V Y++L P+G GAYG+VC+A D + +VAIKKL RPF S +AKR YREL+++ HM HEN++ L+D +TP + + F+D YL+ P MG DL +++ + L + +QFLVYQ+L+GLKY+H++ +IHRDLKP N+AVNEDCELKILDFGLARQ D EMTGYV TRWYRAPE++L+WM YT VDIWSVGCIMAE+ T K LF GNDH+DQLK+IM++ GTP EF+ K+ S +A+ ++ E + +KDF S + A++LL+RMLVLD ++R++A +AL HPY D DEP A + D + DVD LE WK + + +F P
Sbjct: 11 FYRQEVTKTAWEVRAVYQDLQPVGSGAYGAVCSAVDSRTGNKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDESLDDFTDFYLVMPFMGTDLGKLMKHETLSEDRIQFLVYQMLKGLKYIHAAGVIHRDLKPGNLAVNEDCELKILDFGLARQADSEMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKILFKGNDHLDQLKEIMKITGTPPPEFVQKLQSAEAKNYM-EGLPELEKKDFASVLTNASP--QAVNLLERMLVLDAEQRVTAAEALTHPYFESLRDTEDEPKAQKYDDSFD---DVDRTLEEWKRVTYKEVLSFKP 353
BLAST of Mitogen-activated protein kinase vs. Ensembl Mouse
Match: Mapk14 (mitogen-activated protein kinase 14 [Source:MGI Symbol;Acc:MGI:1346865]) HSP 1 Score: 367.081 bits (941), Expect = 2.857e-120 Identity = 167/246 (67.89%), Postives = 201/246 (81.71%), Query Frame = 1
Query: 1546 FQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSE 2283
F + + W VP RY+NL+P+G GAYGSVCAAFD K +VA+KKL+RPF S +AKRTYREL+++ HM HEN++ L+D +TP + E F+DVYL+T LMGADLN I++ Q+L ++HVQFL+YQILRGLKY+HS++IIHRDLKPSN+AVNEDCELKILDFGLAR TD+EMTGYVATRWYRAPEIML+WMHY VDIWSVGCIMAEL T + LFPG DHIDQLK I+ L GTP E + KI SE
Sbjct: 8 FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSE 253
BLAST of Mitogen-activated protein kinase vs. UniProt/SwissProt
Match: sp|Q9WUI1|MK11_MOUSE (Mitogen-activated protein kinase 11 OS=Mus musculus OX=10090 GN=Mapk11 PE=1 SV=2) HSP 1 Score: 436.802 bits (1122), Expect = 9.377e-145 Identity = 207/349 (59.31%), Postives = 265/349 (75.93%), Query Frame = 1
Query: 1540 AEFQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTP 2586
A F + + W VP R + L P+G GAYGSVC+A+D +L+++VA+KKL+RPF S +A+RTYREL+++ H+ HEN++ L+D +TP ++ E FS+VYL+T LMGADLN I++ Q L +EHVQFLVYQ+LRGLKY+HS+ IIHRDLKPSN+AVNEDCEL+ILDFGLARQ DEEMTGYVATRWYRAPEIML+WMHY VDIWSVGCIMAEL K LFPGND+IDQLK+IME+ GTP E + KI SE AR +I + + P+KD +S F + + AIDLL RMLVLD D+R+SA +ALAH Y + YHD DEP A + + +E K + LE WK+ + + +F P
Sbjct: 6 AGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGNDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYI-QSLPPMPQKDLSSVF--HGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPDDEPEAEPYDESVEAK-ERTLEEWKELTYQEVLSFKP 350
BLAST of Mitogen-activated protein kinase vs. UniProt/SwissProt
Match: sp|Q16539|MK14_HUMAN (Mitogen-activated protein kinase 14 OS=Homo sapiens OX=9606 GN=MAPK14 PE=1 SV=3) HSP 1 Score: 433.335 bits (1113), Expect = 2.016e-143 Identity = 207/347 (59.65%), Postives = 260/347 (74.93%), Query Frame = 1
Query: 1546 FQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTP 2586
F + + W VP RY+NL+P+G GAYGSVCAAFD K +VA+KKL+RPF S +AKRTYREL+++ HM HEN++ L+D +TP + E F+DVYL+T LMGADLN I++ Q+L ++HVQFL+YQILRGLKY+HS++IIHRDLKPSN+AVNEDCELKILDFGLAR TD+EMTGYVATRWYRAPEIML+WMHY VDIWSVGCIMAEL T + LFPG DHIDQLK I+ L GTP E + KI SE AR +I+ Q P+ +F + F + A+DLL++MLVLD D+RI+A ALAH Y A YHD DEP A + E + D+ ++ WK +D + +F P
Sbjct: 8 FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLTQM-PKMNFANVF--IGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESR-DLLIDEWKSLTYDEVISFVP 350
BLAST of Mitogen-activated protein kinase vs. UniProt/SwissProt
Match: sp|P47811|MK14_MOUSE (Mitogen-activated protein kinase 14 OS=Mus musculus OX=10090 GN=Mapk14 PE=1 SV=3) HSP 1 Score: 433.335 bits (1113), Expect = 2.105e-143 Identity = 206/337 (61.13%), Postives = 257/337 (76.26%), Query Frame = 1
Query: 1576 WTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTP 2586
W VP RY+NL+P+G GAYGSVCAAFD K +VA+KKL+RPF S +AKRTYREL+++ HM HEN++ L+D +TP + E F+DVYL+T LMGADLN I++ Q+L ++HVQFL+YQILRGLKY+HS++IIHRDLKPSN+AVNEDCELKILDFGLAR TD+EMTGYVATRWYRAPEIML+WMHY VDIWSVGCIMAEL T + LFPG DHIDQLK I+ L GTP E + KI SE AR +I+ Q P+ +F + F + A+DLL++MLVLD D+RI+A ALAH Y A YHD DEP A + E + D+ ++ WK +D + +F P
Sbjct: 18 WEVPERYQNLSPVGSGAYGSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLAQM-PKMNFANVF--IGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESR-DLLIDEWKSLTYDEVISFVP 350
BLAST of Mitogen-activated protein kinase vs. UniProt/SwissProt
Match: sp|Q15759|MK11_HUMAN (Mitogen-activated protein kinase 11 OS=Homo sapiens OX=9606 GN=MAPK11 PE=1 SV=2) HSP 1 Score: 433.335 bits (1113), Expect = 2.245e-143 Identity = 205/347 (59.08%), Postives = 263/347 (75.79%), Query Frame = 1
Query: 1540 AEFQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNF 2580
A F + + W VP R + L P+G GAYGSVC+A+D +L+++VA+KKL+RPF S +A+RTYREL+++ H+ HEN++ L+D +TP ++ E FS+VYL+T LMGADLN I++ Q L +EHVQFLVYQ+LRGLKY+HS+ IIHRDLKPSN+AVNEDCEL+ILDFGLARQ DEEMTGYVATRWYRAPEIML+WMHY VDIWSVGCIMAEL K LFPG+D+IDQLK+IME+ GTP E + KI SE AR +I + + P+KD +S F + AIDLL RMLVLD D+R+SA +ALAH Y + YHD DEP A + + +E K + LE WK+ + + +F
Sbjct: 6 AGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYI-QSLPPMPQKDLSSIF--RGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPEDEPEAEPYDESVEAK-ERTLEEWKELTYQEVLSF 348
BLAST of Mitogen-activated protein kinase vs. UniProt/SwissProt
Match: sp|P70618|MK14_RAT (Mitogen-activated protein kinase 14 OS=Rattus norvegicus OX=10116 GN=Mapk14 PE=1 SV=3) HSP 1 Score: 432.95 bits (1112), Expect = 3.130e-143 Identity = 207/347 (59.65%), Postives = 259/347 (74.64%), Query Frame = 1
Query: 1546 FQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTP 2586
F + + W VP RY+NL+P+G GAYGSVCAAFD K +VA+KKL+RPF S +AKRTYREL+++ HM HEN++ L+D +TP + E F+DVYL+T LMGADLN I++ Q+L ++HVQFL+YQILRGLKY+HS++IIHRDLKPSN+AVNEDCELKILDFGLAR TD+EMTGYVATRWYRAPEIML+WMHY VDIWSVGCIMAEL T + LFPG DHIDQLK I+ L GTP E + KI SE AR +I+ Q P+ +F + F + A+DLL++MLVLD D+RI+A ALAH Y A YHD DEP A + E + D ++ WK +D + +F P
Sbjct: 8 FYRQELNKTVWEVPERYQNLSPVGSGAYGSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLAQM-PKMNFANVF--IGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVAEPYDQSFESR-DFLIDEWKSLTYDEVISFVP 350
BLAST of Mitogen-activated protein kinase vs. TrEMBL
Match: A0A4E0RTP7 (Mitogen-activated protein kinase OS=Fasciola hepatica OX=6192 GN=D915_005042 PE=4 SV=1) HSP 1 Score: 459.914 bits (1182), Expect = 4.740e-151 Identity = 215/344 (62.50%), Postives = 265/344 (77.03%), Query Frame = 1
Query: 1570 SDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTPRISSL 2601
S W VP RY++L +GHGAYG VC A+D +LQR+VAIKKL +PF EYAKRT+RELKI+ H+DHENI+CLIDA++PQ++ E F DVYL+TPLMGADL A+IR+Q L + H++FLVYQILR LKYMHS+ ++HRDLKP NIAVNEDCELKILDFGLAR+ DE MTGYV TRWYRAPEIML+WMHY VDIWS CIMAEL TRKPLF G +HIDQ+K IM + G PD+E M KI S++AR F+ I +D ++F ++ D AIDLL ++L LDPDRR +A ALAHPY YHD+ DEP F+D +E +TDV LE WK VW+ ++NF P++ SL
Sbjct: 26 SIWLVPERYQDLTLLGHGAYGVVCTAYDTRLQRRVAIKKLTKPFEDKEYAKRTHRELKILSHVDHENILCLIDAFSPQTSLEQFKDVYLVTPLMGADLEAVIRSQSLSDGHIRFLVYQILRALKYMHSAGLVHRDLKPVNIAVNEDCELKILDFGLARRKDEVMTGYVTTRWYRAPEIMLNWMHYNESVDIWSTACIMAELRTRKPLFTGKNHIDQIKMIMRVLGKPDEECMKKITSQNARDFV-ASIAIEEPQDLYTYFAGFSPD--AIDLLQKLLHLDPDRRYTATQALAHPYFQGYHDDQDEPVGEPFIDPLEDRTDVSLEEWKKHVWNALENFVPKLDSL 366
BLAST of Mitogen-activated protein kinase vs. TrEMBL
Match: A0A3Q0KM47 (Mitogen-activated protein kinase OS=Schistosoma mansoni OX=6183 PE=4 SV=1) HSP 1 Score: 452.981 bits (1164), Expect = 1.808e-148 Identity = 213/361 (59.00%), Postives = 271/361 (75.07%), Query Frame = 1
Query: 1519 SHLDNMAAEFQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTPRISSL 2601
S N+ + F + +W VP+RY L+ IG+GAYG+VC+A D+KL R+VAIKKL+RPF + EY KRTYRE+ I+ MDHENIVCLIDA++PQ++ + FSD+YL+TPLMGADL AII TQ L +E ++FLVYQILRGLKYMHS +IHRDLKP+NIAVNEDCELKILDFGLARQ EEMTGYVATRWYRAPE+ML+WMHY VD+WSV CIMAEL R PLF G +HI Q++ I+ L G PD+EFM KI S +A FIR+ + P ++ ++F ++ D A+DLL +ML LDPDRR++A ALAH Y YHDE DEP A F D + ++V L+ K+ VW+ ++NF P ++SL
Sbjct: 2 SSAKNLKSGFVSLQLNQVEWCVPSRYNELSMIGYGAYGTVCSAHDNKLNRRVAIKKLSRPFENIEYTKRTYREINILSQMDHENIVCLIDAFSPQTSLKEFSDIYLVTPLMGADLGAIIETQSLSDEQIRFLVYQILRGLKYMHSIGLIHRDLKPANIAVNEDCELKILDFGLARQKQEEMTGYVATRWYRAPEVMLNWMHYNESVDVWSVACIMAELRNRAPLFKGGNHIHQIQLILNLLGKPDEEFMRKINSPEACGFIRDISKCEP-QNLYTYFSSFSSD--AVDLLQKMLHLDPDRRLTAAQALAHRYFTTYHDESDEPIAERFDDPFQDDSNVSLDQLKEAVWNTLENFVPNLNSL 359
BLAST of Mitogen-activated protein kinase vs. TrEMBL
Match: A0A4S2L8C7 (Mitogen-activated protein kinase OS=Opisthorchis felineus OX=147828 GN=CRM22_009273 PE=4 SV=1) HSP 1 Score: 451.44 bits (1160), Expect = 1.143e-147 Identity = 207/367 (56.40%), Postives = 274/367 (74.66%), Query Frame = 1
Query: 1501 SNTHKPSHLDNMAAEFQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTPRISSL 2601
S +KP + +F H+ WTVP RY +L+ IGHG YG+VC+A+D +L R+VAIKKL +PF EYAKRTYREL+I+ H+ HENI+CLIDA++PQS+ ++F D+YL+TP M ADL+A++RTQ+L + H++FL+YQ+LR LKY+HS +IHRDLKP NI VNEDCELK+LDFGLARQ D+EMTGYVATRWYRAPEIML+W HY +VDIWSV CIM+EL TRKPLFPG +HIDQL++I+ L G PD+ +M K+ AR+FI + ++ + D N +F + E+ +DLL +L LDPDRR +A ALAH Y YHDE DEPT FVD +E DV ++ WK+ +W ++NF P+++SL
Sbjct: 10 SQNNKPGKPGFVTVDFN-----HTQWTVPERYRDLSLIGHGVYGAVCSAYDSQLHRRVAIKKLTKPFDDSEYAKRTYRELRILAHVSHENILCLIDAFSPQSSLDTFKDLYLVTPFMAADLSAVVRTQDLSDSHIRFLIYQLLRALKYLHSCGLIHRDLKPGNIGVNEDCELKLLDFGLARQRDDEMTGYVATRWYRAPEIMLNWTHYNEQVDIWSVACIMSELRTRKPLFPGRNHIDQLRRIICLLGKPDELYMEKVTGAGARSFI-DNLEVTDPSDLNVYFSDFP--EDGVDLLRHLLQLDPDRRYTASQALAHRYFELYHDEQDEPTGDRFVDALEEAKDVSVQEWKEHIWKTLENFVPKLNSL 368
BLAST of Mitogen-activated protein kinase vs. TrEMBL
Match: A0A4Z2CN26 (Mitogen-activated protein kinase OS=Schistosoma japonicum OX=6182 GN=EWB00_009122 PE=4 SV=1) HSP 1 Score: 448.358 bits (1152), Expect = 1.221e-146 Identity = 210/361 (58.17%), Postives = 271/361 (75.07%), Query Frame = 1
Query: 1519 SHLDNMAAEFQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTPRISSL 2601
S ++ + F + +W VP+RY +L+ IG+GAYG+VC+A D +L R+VAIKKL+RPF + EY KRTYRE+ I+ MDHENIVCLIDA++PQ++ + F+D+YL+TPLMGADL AII TQ L +E ++FLVYQILRGLKYMHS +IHRDLKP+NIAVNEDCELKILDFGLARQ EEMTGYVATRWYRAPE+ML+WMHY VD+WSV CIMAEL R PLF G +HI Q++ I+ L G PD+EFM KI S +A FIR+ + P ++ ++F ++ D A+DLL +ML LDPDRR++A ALAH Y A YHDE DEP A F D + ++ L+ K+ VW+ ++NF P ++SL
Sbjct: 2 SSTKDLKSGFVSLQLNQVEWCVPSRYSDLSMIGYGAYGTVCSAHDDRLNRRVAIKKLSRPFENIEYTKRTYREINILSQMDHENIVCLIDAFSPQASLKEFTDIYLVTPLMGADLGAIIETQSLSDEQIRFLVYQILRGLKYMHSIGLIHRDLKPANIAVNEDCELKILDFGLARQKQEEMTGYVATRWYRAPEVMLNWMHYNESVDVWSVACIMAELRNRTPLFKGGNHIHQIQLILNLLGKPDEEFMGKINSPEACGFIRDISKCEP-QNLYTYFSSFSSD--AVDLLQQMLHLDPDRRLTAAQALAHRYFATYHDESDEPVAEKFDDPFQDDSNASLDQLKEAVWNTLENFVPNLNSL 359
BLAST of Mitogen-activated protein kinase vs. TrEMBL
Match: A0A2U9K5Z7 (Mitogen-activated protein kinase OS=Bugula neritina OX=10212 PE=2 SV=1) HSP 1 Score: 446.432 bits (1147), Expect = 5.977e-146 Identity = 215/342 (62.87%), Postives = 259/342 (75.73%), Query Frame = 1
Query: 1576 WTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTPRISSL 2601
W VP RY+ L+P+G GAYG VC+A D + +VAIKKL RPF SP +A+RT+RE+K++ HM+HENI+ L+ +TP ++ E FSDVYL+T LMGADLN I+RTQ+L +EHVQFL+YQILRGLKY+HS+ IIHRDLKPSNIAVNEDCELKILDFGLARQ D+ MTGYVATRWYRAPEIML+WMHY VDIWSVGCIMAEL T K LFPGND IDQL KIM+L GTP EF+ +I S++AR +I +Q P++DF +F D A+DLL+RML LD DRRI+A +AL HPYLA YHDE DEP A F D E + + W+ VW NF PR L
Sbjct: 25 WEVPKRYQMLSPVGTGAYGQVCSALDTEKNMKVAIKKLTRPFQSPIHARRTFREIKMLKHMNHENIIGLLAIFTPATSIEKFSDVYLVTNLMGADLNNIVRTQKLTDEHVQFLIYQILRGLKYVHSAGIIHRDLKPSNIAVNEDCELKILDFGLARQADDSMTGYVATRWYRAPEIMLNWMHYNRTVDIWSVGCIMAELMTGKTLFPGNDQIDQLHKIMKLVGTPGPEFLKRITSDEARRYI-ASLQVMPKRDFREYFLGSNPD--ALDLLERMLDLDADRRITAPEALRHPYLAQYHDESDEPEAEPFDDSFE-HVEKTVADWRLAVWGETNNFIPREEQL 362
BLAST of Mitogen-activated protein kinase vs. Ensembl Cavefish
Match: mapk11 (mitogen-activated protein kinase 11 [Source:NCBI gene;Acc:103035641]) HSP 1 Score: 436.802 bits (1122), Expect = 9.684e-146 Identity = 203/350 (58.00%), Postives = 266/350 (76.00%), Query Frame = 1
Query: 1546 FQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTPRIS 2595
F + + W VP RY+NL P+G GAYGSVC+A+D +L+++VA+KKL+RPF S +++R+YREL+++ HM HEN++ L+D ++P ++ E F++VYL+T LMGADLN I++ Q L +EHVQFL+YQ+LRGLKY+HS+ +IHRDLKPSN+AVNEDCEL+ILDFGLARQTD+EMTGYVATRWYRAPEIML+WMHY VDIWSVGCIM EL K LFPGND+IDQLK+IME+ GTP + + KI SE A+ +I + + P++D F + A+DLL +MLVLD DRRISA +AL HPY + YHD DEP APL+ E K D LE WKD V++ + +F +S
Sbjct: 7 FYRQELNKTVWEVPERYQNLTPVGSGAYGSVCSAYDVRLRQKVAVKKLSRPFQSLIHSRRSYRELRLLKHMKHENVIGLLDVFSPAASLEEFNEVYLVTNLMGADLNNIVKFQRLSDEHVQFLIYQLLRGLKYIHSAGLIHRDLKPSNVAVNEDCELRILDFGLARQTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMGELLKGKVLFPGNDYIDQLKRIMEVVGTPTPDLLKKISSEHAQKYI-QSLPYMPQQDLGKIF--RGANPMAVDLLKKMLVLDCDRRISASEALCHPYFSQYHDPEDEPEAPLYDQTPESK-DCTLEEWKDLVFEEVNSFKAPVS 352
BLAST of Mitogen-activated protein kinase vs. Ensembl Cavefish
Match: mapk14a (mitogen-activated protein kinase 14A-like [Source:NCBI gene;Acc:103046996]) HSP 1 Score: 436.032 bits (1120), Expect = 1.884e-145 Identity = 206/350 (58.86%), Postives = 265/350 (75.71%), Query Frame = 1
Query: 1543 EFQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTPRI 2592
+F + + W VP RY+NL+P+G GAYGSVC+A D K+ +VA+KKL+RPF S +AKRTYREL+++ HM HEN++ L+DA+TP ++ E F+DVYL+T LMGADLN I++ Q+L ++HVQFL+YQI+RGLKY+HS++IIHRDLKP N+AVNEDCELKILDFGLAR TD+EMTGYVATRWYRAPEIML+WMHY VDIWSVGCIMAEL T + LFPG DHIDQLK IM L GTP E + KI S+ AR +I + P+++F F + A+DLL++MLVLD D+RI+A +ALAHPY A YHD DEP A + E + ++D+E WK ++ + NF P I
Sbjct: 8 KFYRQEVNKTIWEVPLRYQNLSPVGSGAYGSVCSAVDEKMGLKVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDAFTPATSLEGFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQIIRGLKYIHSADIIHRDLKPGNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNMTVDIWSVGCIMAELLTGRALFPGTDHIDQLKLIMMLVGTPGPELLKKISSDSARNYIH-SLPNMPKRNFADVF--IGANPQAVDLLEKMLVLDTDKRITAAEALAHPYFAQYHDPDDEPEADPYDQSFESR-ELDIEEWKRLTYEEVINFEPPI 353
BLAST of Mitogen-activated protein kinase vs. Ensembl Cavefish
Match: mapk14a (mitogen-activated protein kinase 14A-like [Source:NCBI gene;Acc:103046996]) HSP 1 Score: 430.254 bits (1105), Expect = 4.152e-143 Identity = 201/350 (57.43%), Postives = 266/350 (76.00%), Query Frame = 1
Query: 1543 EFQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTPRI 2592
+F + + W VP RY+NL+P+G GAYGSVC+A D K+ +VA+KKL+RPF S +AKRTYREL+++ HM HEN++ L+DA+TP ++ E F+DVYL+T LMGADLN I++ Q+L ++HVQFL+YQI+RGLKY+HS++IIHRDLKP N+AVNEDCELKILDFGLAR TD+EMTGYVATRWYRAPEIML+WMHY VDIWSVGCIMAEL T + LFPG DHI+QL++IM L GTP ++++ S +AR +I + P+++F F + A+DLL++MLVLD D+RI+A +ALAHPY A YHD DEP A + E + ++D+E WK ++ + NF P I
Sbjct: 8 KFYRQEVNKTIWEVPLRYQNLSPVGSGAYGSVCSAVDEKMGLKVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDAFTPATSLEGFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQIIRGLKYIHSADIIHRDLKPGNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNMTVDIWSVGCIMAELLTGRALFPGTDHINQLQQIMRLTGTPPSSLISRMPSHEARNYIH-SLPNMPKRNFADVF--IGANPQAVDLLEKMLVLDTDKRITAAEALAHPYFAQYHDPDDEPEADPYDQSFESR-ELDIEEWKRLTYEEVINFEPPI 353
BLAST of Mitogen-activated protein kinase vs. Ensembl Cavefish
Match: mapk14b (mitogen-activated protein kinase 14A [Source:NCBI gene;Acc:103028137]) HSP 1 Score: 421.779 bits (1083), Expect = 7.210e-140 Identity = 197/339 (58.11%), Postives = 261/339 (76.99%), Query Frame = 1
Query: 1576 WTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTPRI 2592
W VP RY+NL+P+G GAYGSVC+A+D + ++A+KKL+RPF S +AKRTYREL+++ HM HEN++ L+D +TP + E F+DVYL+T LMGADLN I++ Q+L ++HVQFL+YQILRGLKY+HS++IIHRDLKPSN+AVNEDCELKILDFGLAR TD+EMTGYVATRWYRAPEIML+WMHY VDIWSVGCIMAEL T + LFPG DHI+QL++IM L GTP ++++ S +AR +I + P+++F F + A+DLL++MLVLD D+RI+A +ALAHPY A YHD DEP A + E + ++D+E WK ++ + +F P +
Sbjct: 19 WEVPERYQNLSPVGSGAYGSVCSAYDIQSGLKIAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPATNLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNMTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPASLISRMPSHEARNYIN-SLPHMPKRNFADVF--IGANPLAVDLLEKMLVLDTDKRITASEALAHPYFAQYHDPDDEPEADPYDQSFESR-ELDIEEWKRLTYEEVLSFEPPV 353
BLAST of Mitogen-activated protein kinase vs. Ensembl Cavefish
Match: mapk14a (mitogen-activated protein kinase 14A-like [Source:NCBI gene;Acc:103046996]) HSP 1 Score: 411.379 bits (1056), Expect = 5.417e-136 Identity = 199/350 (56.86%), Postives = 255/350 (72.86%), Query Frame = 1
Query: 1543 EFQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTPRI 2592
+F + + W VP RY+NL+P+G GAYGSVC+A D K+ +VA+KKL+RPF S +AKRTYREL+++ HM HEN++ L+DA+TP ++ E F+DVYL+T LMGADLN I++ Q+L ++HVQFL+YQI+RGLK DLKP N+AVNEDCELKILDFGLAR TD+EMTGYVATRWYRAPEIML+WMHY VDIWSVGCIMAEL T + LFPG DHIDQLK IM L GTP E + KI S+ AR +I + P+++F F + A+DLL++MLVLD D+RI+A +ALAHPY A YHD DEP A + E + ++D+E WK ++ + NF P I
Sbjct: 8 KFYRQEVNKTIWEVPLRYQNLSPVGSGAYGSVCSAVDEKMGLKVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDAFTPATSLEGFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQIIRGLK----------DLKPGNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNMTVDIWSVGCIMAELLTGRALFPGTDHIDQLKLIMMLVGTPGPELLKKISSDSARNYIH-SLPNMPKRNFADVF--IGANPQAVDLLEKMLVLDTDKRITAAEALAHPYFAQYHDPDDEPEADPYDQSFESR-ELDIEEWKRLTYEEVINFEPPI 343
BLAST of Mitogen-activated protein kinase vs. Ensembl Sea Lamprey
Match: mapk14a (mitogen-activated protein kinase 14a [Source:NCBI gene;Acc:65237]) HSP 1 Score: 399.438 bits (1025), Expect = 6.397e-132 Identity = 192/341 (56.30%), Postives = 251/341 (73.61%), Query Frame = 1
Query: 1576 WTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDH----IDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTP 2586
W VP RY NL +G GAYGSVC++ D K +VA+KKL+RPF S +AKRTYREL+++ HM HEN++ L+D +TP S+ E F D+YL+T LMGADLN I++ Q+L ++HVQFLVYQILRGLKY+HS+ IIHRDLKPSN+AVNEDCELKILDFGLAR D+EMTGYVATRWYRAPEIML+WMHY VDIWSVGCIMAEL T + LFPG D I+QL KI++L GTP + ++++ S++AR +I + + + ++DF F + +DLL+RMLVLD D+RI+A +AL H Y A YHD DEP A + E + + +E W+ ++ + +F P
Sbjct: 19 WEVPRRYVNLTSVGSGAYGSVCSSLDTKTGMKVAVKKLSRPFQSVIHAKRTYRELRLLKHMKHENVIGLMDVFTPNSSLEEFDDLYLVTDLMGADLNNIVKCQKLTDDHVQFLVYQILRGLKYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDRILSDINQLVKILQLTGTPPQYLIDRMQSKEARNYI-QSLPYTQKRDFKDVFL--GANPLVVDLLERMLVLDTDQRITAAEALVHQYFAQYHDPDDEPEAEPYDQSFENQ-EFPVEEWRRLTYEEVISFVP 355
BLAST of Mitogen-activated protein kinase vs. Ensembl Sea Lamprey
Match: mapk12a (mitogen-activated protein kinase 12a [Source:NCBI gene;Acc:30681]) HSP 1 Score: 360.918 bits (925), Expect = 4.261e-117 Identity = 171/334 (51.20%), Postives = 232/334 (69.46%), Query Frame = 1
Query: 1576 WTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLET--WKDTVWDFI 2571
W VP RY L +G GAYG+VC++ D +VA+KKL RPF S +AKR YREL+++ HM HEN++ L+D +TP T + F D YL+ P MG DL+ I++ + ++ VQ+L+YQIL+GLKY+HSS IIHRDLKP N+AVNEDCELKILDFGLAR D+EMTGYV TRWYRAPE++L+WMHYT VDIWSVGCIMAE+ T KPLFPGNDH+DQL I++L GTP + ++++ +A +I+ + R+ F + AIDLL++ML LDP++R +A +AL HP+ ++ + +E A + EG V+LET WK + +
Sbjct: 21 WEVPKRYSQLFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFMGTDLSKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARHADQEMTGYVVTRWYRAPEVILNWMHYTQTVDIWSVGCIMAEMITGKPLFPGNDHMDQLMLILKLTGTPPQYLVDRMDENEAAKYIKTLPKMEKRRISTVF---PNANPIAIDLLEKMLALDPEQRPTASEALQHPFFSETREPLEETEAEPYDQTFEG---VELETSEWKSNDFSLV 348
BLAST of Mitogen-activated protein kinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000729.1 (pep scaffold:Pmarinus_7.0:GL477416:20288:37329:-1 gene:ENSPMAG00000000656.1 transcript:ENSPMAT00000000729.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 301.597 bits (771), Expect = 9.977e-94 Identity = 161/368 (43.75%), Postives = 226/368 (61.41%), Query Frame = 1
Query: 1534 MAAEFQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEE--MTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQY-------------TKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHD-EPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTPR 2589
+ +F + S +TV RY+NL PIG GA G VCAA+D R VAIKKL+RPF + +AKR YREL ++ ++H+NI+CL + +TPQ + E F DVYL+ LM A+L +I+ EL +E + +L+YQ+L G+K++HS+ IIHRDLKPSNI V DC LKILDFGLAR MT YV TR+YRAPE++L M YT VDIWSVGC++ E+ + LFPG D+IDQ KI+E GTP EFM K+ + +R ++ P+ SF + K A DLL +MLV+DP +RI+ ALAHPY+ ++D + E P D + + ++ WK+ ++ + ++ R
Sbjct: 6 LETQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDIMQNRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVIQM-ELDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVILG-MGYTENVDIWSVGCVLGEMIRHRILFPGKDYIDQWNKIIEQLGTPMAEFMKKL-----QPTVRNYVENRPKYAGYSFEKLFPDVLFPADSENNRLKASQARDLLSKMLVIDPAKRINVDQALAHPYINIWYDPSEVEAPPPKIYDKQLDEREHSIDEWKELIYKEVLDWEER 366
BLAST of Mitogen-activated protein kinase vs. Ensembl Sea Lamprey
Match: mapk1 (mitogen-activated protein kinase 1 [Source:ZFIN;Acc:ZDB-GENE-030722-2]) HSP 1 Score: 296.204 bits (757), Expect = 1.681e-92 Identity = 161/374 (43.05%), Postives = 231/374 (61.76%), Query Frame = 1
Query: 1495 CCSNTHKPSHL--DNMAAEFQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEE------MTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTA--PLFVDVMEGKTDVDLETWKDTVWDFIQNFTP 2586
C + P + A Q + + V RY +L+ IG GAYG VCAAFD+ +VAIKK++ PF Y +RT RE+KI+ HENI+ + D ST + DVY++ LM DL +++ Q+L N+H+ + +YQILRGLKY+HS+ ++HRDLKPSN+ +N C+LKI DFGLAR D + +T YVATRWYRAPEIML+ YT +DIWSVGCI+AE+ + +PLFPG ++DQL I+ + G+P +E ++ I++ AR ++ + + + +N F + D A+DLLD+ML +P RRI+ ++ALAHPYL Y+D DEP A P D ME D+ E K+ +++ F P
Sbjct: 1 CAARAQGPPKMATPTQGAAQQPEVVKGQVFDVGPRYTSLSYIGEGAYGMVCAAFDNVKLVRVAIKKIS-PFEHQTYCQRTLREIKILLRFKHENIIGINDILR-ASTIDQMKDVYIVQDLMETDLYKLLKGQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPLFPGKHYLDQLNHILGILGSPSQEDLDCIINMKARNYL-QSLPPKAKVPWNRLFPK--ADSKALDLLDKMLTFNPHRRITVEEALAHPYLEQYYDPSDEPVAEEPFRFD-ME-LDDLPKERLKEMIFEETARFQP 367
BLAST of Mitogen-activated protein kinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002110.1 (pep scaffold:Pmarinus_7.0:GL476899:162663:183382:1 gene:ENSPMAG00000001908.1 transcript:ENSPMAT00000002110.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 271.166 bits (692), Expect = 2.493e-84 Identity = 137/289 (47.40%), Postives = 190/289 (65.74%), Query Frame = 1
Query: 1606 NPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHD 2472
+P G+GA+GS +A D +VA+KKL+RPF S +AKR YREL+++ HM+HEN++ L+D +TP + F+D+YL+T LMGADLN I++ Q+L ++HVQFLVYQ LRGLKY+HS+ IIHRDLKPSN+AVNEDCELK+ DE+ Y ++YR ++ + Y R+DIWSVGCIMAEL T + LFPG D+IDQLK IM+L GTP E M KI S+ AR +I + + ++DF F + N ++ + VL+ R+ + A + HD
Sbjct: 1 SPTGNGAFGS--SALDRHRAMKVAVKKLSRPFQSLIHAKRAYRELRLLKHMNHENVIGLLDVFTPDKSLGVFNDMYLVTHLMGADLNNIVKCQKLTDDHVQFLVYQTLRGLKYIHSAGIIHRDLKPSNLAVNEDCELKVSGSRNNSTPDEDRLHYYTLQYYRFFHSNINVILYGQRMDIWSVGCIMAELLTGRALFPGTDYIDQLKLIMQLVGTPGPELMQKISSDSARNYI-QSLPVMKKRDFRDVFL--GANPNVVECCGAVRVLERRGRLFVELGFARRSIVQEHD 284
BLAST of Mitogen-activated protein kinase vs. Ensembl Yeast
Match: HOG1 (Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]) HSP 1 Score: 338.191 bits (866), Expect = 1.192e-107 Identity = 167/347 (48.13%), Postives = 230/347 (66.28%), Query Frame = 1
Query: 1543 EFQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQY-TKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNF 2580
EF I + + + RY +LNP+G GA+G VC+A D + VAIKK+ +PF + AKRTYRELK++ H+ HEN++CL D + D+Y +T L G DL+ +++T+ L + VQ+ +YQILRGLKY+HS+ +IHRDLKPSNI +NE+C+LKI DFGLAR D +MTGYV+TR+YRAPEIML+W Y VDIWS GCI AE+ KPLFPG DH+ Q I +L G+P K+ +N I SE+ F + + P +D F ++ T + +A+DLL++MLV DP +RI+A DALAHPY A YHD DEP A D D+ ++TW+ ++ I +F
Sbjct: 6 EFIRTQIFGTVFEITNRYNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLRHENLICLQDIFL-----SPLEDIYFVTELQGTDLHRLLQTRPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVINTICSENTLKF----VTSLPHRDPIPFSERFKTVEPDAVDLLEKMLVFDPKKRITAADALAHPYSAPYHDPTDEPVADAKFDWHFNDADLPVDTWRVMMYSEILDF 343
BLAST of Mitogen-activated protein kinase vs. Ensembl Yeast
Match: FUS3 (Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]) HSP 1 Score: 279.641 bits (714), Expect = 1.020e-86 Identity = 154/365 (42.19%), Postives = 214/365 (58.63%), Query Frame = 1
Query: 1531 NMAAEFQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEE-------------MTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEF-MNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTA----PLFVDVMEGKTDVDLETWKDTVWDFI 2571
N++++FQL ++ +G GAYG VC+A VAIKK+ PF P +A RT RE+KI+ H HENI+ + + P S E+F++VY+I LM DL+ +I TQ L ++H+Q+ +YQ LR +K +H S +IHRDLKPSN+ +N +C+LK+ DFGLAR DE MT YVATRWYRAPE+ML+ Y+ +D+WS GCI+AELF R+P+FPG D+ QL I + GTP + + I S AR +I+ + P F + + IDLL RMLV DP +RI+AK+AL HPYL YHD +DEP P F + K + + K +W+ I
Sbjct: 8 NISSDFQLKSL----------------LGEGAYGVVCSATHKPTGEIVAIKKI-EPFDKPLFALRTLREIKILKHFKHENIITIFNIQRPDSF-ENFNEVYIIQELMQTDLHRVISTQMLSDDHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLLINSNCDLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFLRRPIFPGRDYRHQLLLIFGIIGTPHSDNDLRCIESPRAREYIKS-LPMYPAAPLEKMFPRV--NPKGIDLLQRMLVFDPAKRITAKEALEHPYLQTYHDPNDEPEGEPIPPSFFEFDHYKEALTTKDLKKLIWNEI 351
BLAST of Mitogen-activated protein kinase vs. Ensembl Yeast
Match: KSS1 (Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]) HSP 1 Score: 275.018 bits (702), Expect = 9.598e-85 Identity = 146/321 (45.48%), Postives = 208/321 (64.80%), Query Frame = 1
Query: 1582 VPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHM-DHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQE-----LLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLAR----QTDEE------MTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAP 2496
+P++Y+ ++ IG GAYG+VC+A +VAIKK+ +PF + RT RE+K++ + +HENI+ ++D P S + + VYL+ LM DL +I Q L ++HVQ+ YQILR LK +HS+++IHRD+KPSN+ +N +C+LK+ DFGLAR +D MT YVATRWYRAPEIML++ YT +DIWS GCI+AE+ + KPLFPG D+ QL I+E+ GTP E N+I S+ A+ +I + P + + + + + + IDLLD+ML +PD+RISA +AL HPYLA YHD DEP P
Sbjct: 9 IPSQYKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKI-QPFSKKLFVTRTIREIKLLRYFHEHENIISILDKVRPVSI-DKLNAVYLVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVLGTPSFEDFNQIKSKRAKEYI-ANLPMRPPLPWETVWSKTDLNPDMIDLLDKMLQFNPDKRISAAEALRHPYLAMYHDPSDEPEYP 326
BLAST of Mitogen-activated protein kinase vs. Ensembl Yeast
Match: SLT2 (Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway [Source:SGD;Acc:S000001072]) HSP 1 Score: 268.085 bits (684), Expect = 9.653e-81 Identity = 149/362 (41.16%), Postives = 217/362 (59.94%), Query Frame = 1
Query: 1534 MAAEFQLHN--IAHSDWTVPTRYENLNPIGHGAYGSVCAA-FDHKLQ-RQVAIKKLARPFHSPEYAKRTYRELKIIHHM-DHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRT-QELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEE-------MTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNF 2580
MA + + H + + D++V R++ + IGHGAYG VC+A F + VAIKK+ F KR+ RELK++ H H+NI CL D S + +YL LM D++ II++ Q L + H Q YQIL GLKY+HS++++HRDLKP N+ VN DC+LKI DFGLAR E +T YVATRWYRAPEIMLS+ YT +D+WS GCI+AE KP+F G D+++QL +I+++ GTP E + +I S++ + +I + + P+ F + + + A+DLL++ML DP +RI+ +AL HPYL+ +HD DEP + + D+E K V +Q+F
Sbjct: 1 MADKIERHTFKVFNQDFSVDKRFQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGSINGLYLYEELMECDMHQIIKSGQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDYIHQ-LGFIPKVPFVNLYP--NANSQALDLLEQMLAFDPQKRITVDEALEHPYLSIWHDPADEPVCSEKFEFSFESVN-DMEDLKQMVIQEVQDF 358
BLAST of Mitogen-activated protein kinase vs. Ensembl Yeast
Match: KDX1 (Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication [Source:SGD;Acc:S000001644]) HSP 1 Score: 227.639 bits (579), Expect = 1.505e-66 Identity = 123/315 (39.05%), Postives = 185/315 (58.73%), Query Frame = 1
Query: 1573 DWTVPTRYENLNPIGHGAYGSVCAAF--DHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHM-DHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRT-QELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLA-------RQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDE 2484
D+ + + IG G++ +C++ + + VAI+K+ F + KRT RELK++ H+ H NIV L D + + VYL LM DL+ IIR+ Q L + H Q +YQIL LKY+HS+ ++H DLKP N+ VN DC+LKI +FGL+ + D + GY+ + WY+APEI+L++ T VDIWS GCI+AEL RKP+F G D++D L I+++ GTP +E + +I S+ +I + P + F S + A++LL +ML DP +RI+ +DAL HPYL+ +HD +E
Sbjct: 16 DFILNKHFHLTGKIGRGSHSLICSSTYTESNEETHVAIRKIPNAFGNKLSCKRTLRELKLLRHLRGHPNIVWLFDTDIVFYPNGALNGVYLYEELMECDLSQIIRSEQRLEDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWSTGCILAELLGRKPMFEGKDYVDHLNHILQILGTPPEETLQEIASQKVYNYIFQ-FGNIPGRSFESILP--GANPEALELLKKMLEFDPKKRITVEDALEHPYLSMWHDIDEE 327
BLAST of Mitogen-activated protein kinase vs. Ensembl Nematostella
Match: EDO46881 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNM4]) HSP 1 Score: 405.601 bits (1041), Expect = 7.505e-134 Identity = 203/364 (55.77%), Postives = 259/364 (71.15%), Query Frame = 1
Query: 1525 LDNMAAEFQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAF-------DHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTPRIS 2595
+ ++ F + ++ + VP +Y+ L+PIG GAYG VC++ + VAIKKL+RPF S +AKRTYRELK++ HM HEN++ L+D +T S E F DVY++T LMG+DLN I+R Q+L +EHVQFLVYQILRGLKY+HS+ +IHRDLKPSNIAVNEDCELKILDFGLAR TD EMTGYVATRWYRAPEIML+WMHY VDIWSVGCIMAEL T K LFPGNDHIDQL KIM+L G P +F+ KI SE AR +I + + + F+ +F + A+DLL++ML LD D RI+A +AL+HPYLA Y D +DEPT F D + K ++ +E W+ V+ I +F + S
Sbjct: 1 MGDLPPGFYRTELVNTVYEVPRKYQELSPIGTGAYGQVCSSTITEPDPTNPDGPNTVAIKKLSRPFQSTMHAKRTYRELKLLRHMRHENVISLLDVFTTASAFEHFQDVYMVTELMGSDLNGILRFQKLSDEHVQFLVYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELKILDFGLARMTDAEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTSKTLFPGNDHIDQLTKIMQLVGKPSDDFLQKIDSESARNYIAQ-MPDYRKTPFDEYF--VGANPLAVDLLEKMLNLDTDHRITAVEALSHPYLASYADPNDEPTCSTFDDSFDEK-ELSIEGWRALVYQEILDFQQKRS 360
BLAST of Mitogen-activated protein kinase vs. Ensembl Nematostella
Match: EDO40573 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6R5]) HSP 1 Score: 308.145 bits (788), Expect = 2.238e-96 Identity = 155/346 (44.80%), Postives = 227/346 (65.61%), Query Frame = 1
Query: 1576 WTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRT-QELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLAR-------QTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKD---FNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNF 2580
+ V RY+ + IG+GAYG VC+A D + +VA+KK++R F A+RT+RELKI+ H H+NI+C+ D P + F DVY++ LM +DL+ II T Q L EHV++ +YQILRGLKY+HS++++HRDLKPSN+ VNE+ ELKI DFG+AR + MT YVATRWYRAPE+MLS Y+ +D+WSVGCI+AE+ R+PLFPG ++++QL+ I+ + GTP + F+ ++ +E + ++ + P KD F FF + + AI+LL +ML LDP RI+ ++AL HP+L +YH E DEPT +D + E K+ + + I++F
Sbjct: 17 FVVDARYKLIETIGNGAYGVVCSAMDTRTGAKVAVKKISRAFDVLTTARRTHRELKILRHFKHDNIICIRDILKPPVNLDEFDDVYVVLDLMESDLHRIIHTDQPLTTEHVRYFLYQILRGLKYIHSAKVLHRDLKPSNLLVNENAELKIGDFGMARGLCSSPLEQKRFMTEYVATRWYRAPELMLSLNEYSEAIDMWSVGCILAEMIGRRPLFPGANYLNQLQMILSVTGTPSQNFIERMGAERVKTYLNQ----LPHKDPVPFEKFFPKAHPE--AINLLSQMLQLDPKERITVENALQHPFLKEYHSEEDEPTCYSPLDFKFDTVLMTKEALKEAIVNEIKDF 356
BLAST of Mitogen-activated protein kinase vs. Ensembl Nematostella
Match: EDO37435 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFQ0]) HSP 1 Score: 290.041 bits (741), Expect = 3.192e-90 Identity = 145/327 (44.34%), Postives = 211/327 (64.53%), Query Frame = 1
Query: 1534 MAAEFQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAY-TPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEE------MTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTA 2493
MAA + + V RY NLN IG GAYG V A D+ ++AIKK++ PF Y +RT RE+KI+ HENI+ ++D P++ E D+Y++ PLM D+ +++TQ L N+H+ + +YQILRGLKY+HS+ ++HRDLKPSN+ +N C+LKI DFGLAR D + +T YVATRWYRAPEIML+ Y+ +DIWSVGCI+AE+ +PLFPG ++DQL I+ + G+P + + I +E AR+++ + + P+ F F D A+DL++ +L +P++RI+ ++ALAHPYL Y+D DEP A
Sbjct: 1 MAASTGPEVVRGQVFDVAPRYTNLNYIGEGAYGMVVAGVDNTTGERIAIKKIS-PFEHQTYCQRTLREIKILSRFKHENIIGILDIIRAPRA--EDMKDIYIVQPLMETDMYKLLKTQRLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARIADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYSKAIDIWSVGCILAEMLANRPLFPGKHYLDQLNLILNVLGSPIADDLLCIKNEKARSYL-QSLPYKPKTPFIKLFSN--ADAKALDLIENLLAFNPNKRITVEEALAHPYLEQYYDPADEPVA 321
BLAST of Mitogen-activated protein kinase vs. Ensembl Nematostella
Match: EDO45525 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RSV5]) HSP 1 Score: 248.054 bits (632), Expect = 1.167e-74 Identity = 120/245 (48.98%), Postives = 167/245 (68.16%), Query Frame = 1
Query: 1546 FQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEE--MTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKI 2274
F + + + V RY+NL PIG GA G VCAA D +VAIKKL+RPF + +AKR +REL ++ ++H+NI+ L++ +TP T E F+D+YL+ LM A L +I +L +E + +L+YQ+L G+K++H ++IIHRDLKPSNI V DC LKILDFGLAR MT YV TR+YRAPE++L M Y + VD+WS+GCI+AE+ +FPG DHIDQ K+ E GTP + F+N++
Sbjct: 2 FYTAQVGDTIFIVLKRYQNLQPIGSGAQGMVCAAIDTVTGEKVAIKKLSRPFQNVTHAKRAFRELVLMRMVNHKNIIGLLNVFTPDRTLEQFNDLYLVMELMDASLCQVIH-MDLDHERLSYLLYQMLCGVKHLHDADIIHRDLKPSNIVVKSDCSLKILDFGLARTAGSAFMMTPYVVTRYYRAPEVILG-MGYCDNVDVWSIGCILAEMIRGHVMFPGTDHIDQWNKVTEQLGTPSESFLNQL 244
BLAST of Mitogen-activated protein kinase vs. Ensembl Nematostella
Match: EDO30527 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T0K0]) HSP 1 Score: 232.646 bits (592), Expect = 6.048e-68 Identity = 127/290 (43.79%), Postives = 188/290 (64.83%), Query Frame = 1
Query: 1609 PIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRT-QELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLAR--QTDEE--MTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKI-VSEDARAFIREKIQTSPR-KDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYL 2457
PIG+GA+G V + D + ++VA+KK+ + F + ++R YREL+++ + H+N++ ID P + F ++Y+++ LM +DL+ II + Q L +HV+ +YQILRGLKY+ S++I+HRD+KP N+ VN +C LKI DFGLAR + DE MT V T++YR+PE++ HYT VDIWSVGCI AEL +RK LF + QL +I++L GTP E ++K SE A +I ++ P + Q T + A+ LL RMLV +P++RIS DAL+HPYL
Sbjct: 44 PIGYGAFGVVWSVTDPRNGKRVALKKMPKVFQNITSSRRAYRELRMLCTLKHDNVISAIDIVHPGHI-DLFHEIYVVSELMQSDLHKIIVSPQPLTADHVKVFLYQILRGLKYLDSAKILHRDIKPGNLLVNSNCLLKICDFGLARLEEPDESVIMTQEVVTQYYRSPELLTGSTHYTQAVDIWSVGCIFAELLSRKILFQAQSPVQQLNQIIDLLGTPCLEDLSKAGSSEGATKYILQRPHKPPALASLYNLSNQATHE--AVHLLCRMLVFNPNKRISCIDALSHPYL 330
BLAST of Mitogen-activated protein kinase vs. Ensembl Medaka
Match: mapk14b (mitogen-activated protein kinase 14A [Source:NCBI gene;Acc:101162042]) HSP 1 Score: 431.024 bits (1107), Expect = 1.769e-143 Identity = 204/347 (58.79%), Postives = 264/347 (76.08%), Query Frame = 1
Query: 1546 FQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTP 2586
F L + + W VP RY+NL+P+G GAYGSVC+++D K +VA+KKL+RPF S +AKRTYREL+++ HM HEN++ L+D +TP ++ + FSDVYL+T LMGADLN I++ Q+L ++HVQFL+YQILRGLKY+HS+ I+HRDLKPSN+AVNEDCELKILDFGLAR TD+EMTGYVATRWYRAPEIML+WMHY VDIWSVGCIMAEL T + LFPG DHIDQLK IM L GTP E + KI SE AR +I + P+++F F + A+DLL++MLVLD D+RI+A +ALAHPY A YHD DEP A + E + ++++E W+ ++D + +F P
Sbjct: 9 FYLQELNKTVWEVPERYQNLSPVGSGAYGSVCSSYDVKTCLKVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPATSLDEFSDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSAGIVHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNMTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLIMMLVGTPGPELLMKISSEPARNYIN-SLPHMPKRNFADVF--IGANPLAVDLLEKMLVLDTDKRITASEALAHPYFAQYHDPDDEPEAEPYDQSFESR-ELEIEEWRSLIYDEVLSFEP 351
BLAST of Mitogen-activated protein kinase vs. Ensembl Medaka
Match: mapk14b (mitogen-activated protein kinase 14A [Source:NCBI gene;Acc:101162042]) HSP 1 Score: 425.631 bits (1093), Expect = 2.451e-141 Identity = 198/347 (57.06%), Postives = 265/347 (76.37%), Query Frame = 1
Query: 1546 FQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTP 2586
F L + + W VP RY+NL+P+G GAYGSVC+++D K +VA+KKL+RPF S +AKRTYREL+++ HM HEN++ L+D +TP ++ + FSDVYL+T LMGADLN I++ Q+L ++HVQFL+YQILRGLKY+HS+ I+HRDLKPSN+AVNEDCELKILDFGLAR TD+EMTGYVATRWYRAPEIML+WMHY VDIWSVGCIMAEL T + LFPG DHI+QL++IM L GTP ++++ S +AR +I + P+++F F + A+DLL++MLVLD D+RI+A +ALAHPY A YHD DEP A + E + ++++E W+ ++D + +F P
Sbjct: 9 FYLQELNKTVWEVPERYQNLSPVGSGAYGSVCSSYDVKTCLKVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPATSLDEFSDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSAGIVHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNMTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPASLISRMPSHEARNYIN-SLPHMPKRNFADVF--IGANPLAVDLLEKMLVLDTDKRITASEALAHPYFAQYHDPDDEPEAEPYDQSFESR-ELEIEEWRSLIYDEVLSFEP 351
BLAST of Mitogen-activated protein kinase vs. Ensembl Medaka
Match: mapk14a (mitogen-activated protein kinase 14A [Source:NCBI gene;Acc:101160731]) HSP 1 Score: 421.779 bits (1083), Expect = 6.847e-140 Identity = 201/349 (57.59%), Postives = 258/349 (73.93%), Query Frame = 1
Query: 1546 FQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTPRI 2592
F + + W VP RY+NL+P+G GAYGSVC+A+D K +VA+KKL+RPF S +AKRTYREL+++ HM HEN++ L+D +TP ++ + F+DVY + LMGADLN I++ Q+L ++HVQFL+YQILRGLKY+HS++IIHRDLKPSN+AVNEDCELKILDFGLAR TD+EMTGYVATRWYRAPEIML+WMHY VDIWSVGCIMAEL T + LFPG DHIDQLK IM L GTP E + KI SE AR +I + R + F + A+DLL++MLVLD DRRI+A +AL HPY A YHD DEP A + E + D++++ WK ++ + +F P +
Sbjct: 9 FYRQEVNKTIWEVPDRYQNLSPVGSGAYGSVCSAYDTKTGLKVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPATSLKEFTDVYFVNHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARLTDDEMTGYVATRWYRAPEIMLNWMHYNMTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLIMMLVGTPGPELLMKISSESARTYISSLPHMAKRNFADVFI---GANPLAVDLLEKMLVLDTDRRITAAEALEHPYFAQYHDPDDEPEAEPYDQSFESR-DLNIKEWKRLTYEELCSFEPPV 353
BLAST of Mitogen-activated protein kinase vs. Ensembl Medaka
Match: mapk14a (mitogen-activated protein kinase 14A [Source:NCBI gene;Acc:101160731]) HSP 1 Score: 414.461 bits (1064), Expect = 3.918e-137 Identity = 195/349 (55.87%), Postives = 261/349 (74.79%), Query Frame = 1
Query: 1546 FQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTPRI 2592
F + + W VP RY+NL+P+G GAYGSVC+A+D K +VA+KKL+RPF S +AKRTYREL+++ HM HEN++ L+D +TP ++ + F+DVY + LMGADLN I++ Q+L ++HVQFL+YQILRGLKY+HS++IIHRDLKPSN+AVNEDCELKILDFGLAR TD+EMTGYVATRWYRAPEIML+WMHY VDIWSVGCIMAEL T + LFPG DHI+QL++IM L GTP ++++ S +AR +I + +++F F + A+DLL++MLVLD DRRI+A +AL HPY A YHD DEP A + E + D++++ WK ++ + +F P +
Sbjct: 9 FYRQEVNKTIWEVPDRYQNLSPVGSGAYGSVCSAYDTKTGLKVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPATSLKEFTDVYFVNHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARLTDDEMTGYVATRWYRAPEIMLNWMHYNMTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPAALISRMPSHEARTYI-SSLPHMAKRNFADVF--IGANPLAVDLLEKMLVLDTDRRITAAEALEHPYFAQYHDPDDEPEAEPYDQSFESR-DLNIKEWKRLTYEELCSFEPPV 353
BLAST of Mitogen-activated protein kinase vs. Ensembl Medaka
Match: mapk11 (mitogen-activated protein kinase 11 [Source:NCBI gene;Acc:101175696]) HSP 1 Score: 397.127 bits (1019), Expect = 1.665e-130 Identity = 194/348 (55.75%), Postives = 251/348 (72.13%), Query Frame = 1
Query: 1546 FQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELK---ILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNF 2580
F + + W VP RY+NL P+G GAYGSVC+A+D L+++VA+KKL+RPF S + +R+YREL+++ HM HEN++ L+D +TP +T E F+++YL+T LMGADLN I++ Q L +EHVQFL+YQ+LRGLK DLKPSN+AVNEDCEL+ ILDFGLARQTD+EMTGYVATRWYRAPEIML+WMHY VDIWSVGCIM EL K LFPG D+IDQLK+IME+ GTP + + KI SE A+ +I + + P++D F + A+DLL RMLVLD D RISA +AL+HPY + YHD DEP AP + E K D LE WK+ V++ + +F
Sbjct: 7 FYRQELNKTVWEVPERYQNLTPVGSGAYGSVCSAYDVVLRQKVAVKKLSRPFQSLIHGRRSYRELRLLKHMKHENVIGLLDVFTPAATLEDFNELYLVTNLMGADLNNIVKFQRLSDEHVQFLIYQLLRGLK----------DLKPSNVAVNEDCELRVRPILDFGLARQTDDEMTGYVATRWYRAPEIMLNWMHYNQNVDIWSVGCIMGELLKGKVLFPGTDYIDQLKRIMEVVGTPTPDLLKKICSEHAQKYI-QSLPFMPQQDLAKIF--RGANPLAVDLLKRMLVLDCDGRISASEALSHPYFSQYHDPDDEPEAPPYDQTPESK-DRTLEEWKELVFEEVNSF 340
BLAST of Mitogen-activated protein kinase vs. Planmine SMEST
Match: SMESG000075533.1 (SMESG000075533.1) HSP 1 Score: 806.209 bits (2081), Expect = 0.000e+0 Identity = 383/384 (99.74%), Postives = 383/384 (99.74%), Query Frame = 1
Query: 1462 MPRKAWWNALNCCSNTHKPSHLDNMAAEFQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTPRISSLIQSD 2613
MPRK WWNALNCCSNTHKPSHLDNMAAEFQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTPRISSLIQSD
Sbjct: 1 MPRKTWWNALNCCSNTHKPSHLDNMAAEFQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTPRISSLIQSD 384
BLAST of Mitogen-activated protein kinase vs. Planmine SMEST
Match: SMESG000075533.1 (SMESG000075533.1) HSP 1 Score: 753.051 bits (1943), Expect = 0.000e+0 Identity = 360/360 (100.00%), Postives = 360/360 (100.00%), Query Frame = 1
Query: 1534 MAAEFQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTPRISSLIQSD 2613
MAAEFQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTPRISSLIQSD
Sbjct: 1 MAAEFQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTPRISSLIQSD 360
BLAST of Mitogen-activated protein kinase vs. Planmine SMEST
Match: SMESG000075539.1 (SMESG000075539.1) HSP 1 Score: 422.55 bits (1085), Expect = 2.211e-140 Identity = 193/353 (54.67%), Postives = 262/353 (74.22%), Query Frame = 1
Query: 1543 EFQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTPRISSL 2601
+F+ + I +SDW V +RYENL IGHG+ GSVC+AFD + + VAIKKLA PF S + AKRTYRE+KI+HHMDHEN++CLID ++ + R +F+DVY +TPL+ DL+ II + + E++ F +YQILRGLKY+HS+ +IHRDL P NIAVNED EL+ILDFGL+R+ D+ MTGYV +R+YRAPEI+ +YTN++D+WS GCIMAE+ + LF GND DQL++IM++A T + F +I +E+ + + E ++ P DF+ FF QYT+D AIDLL +MLVLDP++RISA DAL HPYL YHDE DE ++D +E +DVD+ETWKD +WD + F P+I +L
Sbjct: 3 KFKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSADRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVPKIENL 355
BLAST of Mitogen-activated protein kinase vs. Planmine SMEST
Match: SMESG000001435.1 (SMESG000001435.1) HSP 1 Score: 296.975 bits (759), Expect = 1.169e-92 Identity = 150/317 (47.32%), Postives = 211/317 (66.56%), Query Frame = 1
Query: 1561 IAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEE------MTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTA 2493
I + V RY +LN IG GAYG V +A+D+ + +VAIKK++ PF Y +RT RE+KI+ HENI+ + D T S E DVY++ LM DL +++TQ+L N+H + +YQILRGLKY+HS+ ++HRDLKPSN+ +N C+LKI DFGLAR D E +T YVATRWYRAPEIML+ YT +DIWSVGCI+AE+ KPLFPG +IDQL I+ + G+P++E ++ IV+ AR ++++ + P+ + S + D+ A+DL++++L +P RI +DALAHPYL Y+D DEP A
Sbjct: 8 IKGQAFEVKPRYIDLNYIGEGAYGMVASAYDNIKKEKVAIKKIS-PFEYQTYCQRTLREIKILTRFKHENIIDIRDIITANSINE-MKDVYIVQCLMETDLFKLLKTQQLSNDHTCYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPEHDHTGLLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLNNKPLFPGKHYIDQLNLILGVLGSPNQEDLDSIVNLKARGYLQQ-LPYKPKVSWKSLYP--NADDQALDLIEKLLTFNPVNRIGVEDALAHPYLKQYYDPADEPVA 319
BLAST of Mitogen-activated protein kinase vs. Planmine SMEST
Match: SMESG000012868.1 (SMESG000012868.1) HSP 1 Score: 293.123 bits (749), Expect = 6.451e-91 Identity = 147/356 (41.29%), Postives = 224/356 (62.92%), Query Frame = 1
Query: 1534 MAAEFQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDE------EMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFT 2583
MA + + + + V +RY NL IG GAYG V +A D+ VAIK+++ PF + +RTYRE+KI+ H HEN++ + + TP S E D+Y++ LM D+ +I+ Q+L NEH+ + +YQILRG+KY+HS+ ++HRDLKPSN+ VN +C+LKI DFGLAR D +T YVATRWYRAPE+ML+ Y+ +D+WS+GCI+AE+ KPLFPG ++ QLK I ++ G+PD E + IV+E AR F+ EK+ P++ + F + +D+LD++L +P +R++A AL HPYL Y++ DEP + + ++ L T K +W+ + ++
Sbjct: 1 MAEDATVQIFRNQPFYVGSRYTNLRFIGEGAYGIVVSATDNVTHEDVAIKRIS-PFEHQTFCQRTYREIKILLHFKHENVIDIKNLLTPASKIEDIKDIYIVQSLMDTDMYKLIKDQKLSNEHICYFLYQILRGVKYIHSANVLHRDLKPSNLLVNSNCDLKICDFGLARVNDPVQDHNGMLTEYVATRWYRAPEVMLNSKGYSKAMDMWSIGCILAEMLGCKPLFPGKHYVQQLKLIFDVLGSPDYEDKSWIVNEKARNFV-EKLIDIPKRPWEELF--PNSEPFCLDILDQLLAFNPSKRLTADKALQHPYLQQYYEPTDEPESDSPFNSEHELDNLSLNTLKQMIWEQVSSYV 352 The following BLAST results are available for this feature:
BLAST of Mitogen-activated protein kinase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30021209 ID=SMED30021209|Name=Mitogen-activated protein kinase|organism=Schmidtea mediterranea sexual|type=transcript|length=2766bpback to top protein sequence of SMED30021209-orf-1 >SMED30021209-orf-1 ID=SMED30021209-orf-1|Name=SMED30021209-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=385bp MPRKAWWNALNCCSNTHKPSHLDNMAAEFQLHNIAHSDWTVPTRYENLNPback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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