Kunitz-type serine protease inhibitor IX

Overview


Name	Kunitz-type serine protease inhibitor IX
Smed ID	SMED30021202
Length (bp)	320

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Kunitz-type serine protease inhibitor IX (SMED30021202) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Kunitz-type serine protease inhibitor IX (SMED30021202) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30021202

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Expressed In	Reference Transcript	Published Transcript	Transcriptome	Publication
parapharyngeal region	SMED30021202	SmedASXL_079259	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
nervous system	SMED30021202	dd_Smed_v4_1274_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30021202	dd_Smed_v4_1274_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30021202	dd_Smed_v4_1274_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30021202	dd_Smed_v4_1274_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30021202	dd_Smed_v4_1274_0_1	dd_Smed_v4	PMID:30962434 Cote et al., 2019

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Human
Match: COL7A1 (collagen type VII alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2214])

HSP 1 Score: 63.1586 bits (152), Expect = 2.078e-12
Identity = 28/54 (51.85%), Postives = 32/54 (59.26%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNA---EKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            C  P++ G C AY LR+Y+ A     E C  F YGGCGGN N F T E CE RC
Sbjct: 2876 CSLPLDEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGNANRFGTREACERRC 2929

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Human
Match: COL6A3 (collagen type VI alpha 3 chain [Source:HGNC Symbol;Acc:HGNC:2213])

HSP 1 Score: 63.1586 bits (152), Expect = 2.567e-12
Identity = 24/56 (42.86%), Postives = 36/56 (64.29%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS*VFA 258
            C  P + G CR + L++YY+   ++C  F YGGCGGN+N F + ++CE  C+ V A
Sbjct: 2504 CKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLA 2559

[Close]

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS*VFA 258
            C  P + G CR + L++YY+   ++C  F YGGCGGN+N F + ++CE  C+ V A
Sbjct: 2505 CKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLA 2560

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Human
Match: COL6A3 (collagen type VI alpha 3 chain [Source:HGNC Symbol;Acc:HGNC:2213])

HSP 1 Score: 63.1586 bits (152), Expect = 2.574e-12
Identity = 24/56 (42.86%), Postives = 36/56 (64.29%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS*VFA 258
            C  P + G CR + L++YY+   ++C  F YGGCGGN+N F + ++CE  C+ V A
Sbjct: 2906 CKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLA 2961

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Human
Match: COL6A3 (collagen type VI alpha 3 chain [Source:HGNC Symbol;Acc:HGNC:2213])

HSP 1 Score: 63.1586 bits (152), Expect = 2.574e-12
Identity = 24/56 (42.86%), Postives = 36/56 (64.29%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS*VFA 258
            C  P + G CR + L++YY+   ++C  F YGGCGGN+N F + ++CE  C+ V A
Sbjct: 2906 CKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLA 2961

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667211:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3d.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 69.707 bits (169), Expect = 3.993e-15
Identity = 30/56 (53.57%), Postives = 37/56 (66.07%), Query Frame = 1

Query:   76 SRAPECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            +RA  C  P E G C  Y LRFY+NA+   C+ F +GGC GN+NNF  +EDCES C
Sbjct:  534 ARATRCSLPKERGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCESAC 589

HSP 2 Score: 62.7734 bits (151), Expect = 1.193e-12
Identity = 24/62 (38.71%), Postives = 36/62 (58.06%), Query Frame = 1

Query:   58 IFKLGESRAPECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            +  + +S    C   +E+G C   F RF ++     C +F YGGCGGN NNF TL++C ++C
Sbjct:  846 VMAMKKSPVATCEADIEVGECAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKC 907

HSP 3 Score: 61.6178 bits (148), Expect = 2.598e-12
Identity = 23/53 (43.40%), Postives = 36/53 (67.92%), Query Frame = 1

Query:   88 ECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS 246
            +C +P+E G C+ +  R+Y+N +  TC  F YGGC GN+N+F T ++CE  C+
Sbjct: 1073 KCLQPVEPGPCKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECEVHCA 1125

HSP 4 Score: 60.8474 bits (146), Expect = 4.794e-12
Identity = 24/53 (45.28%), Postives = 33/53 (62.26%), Query Frame = 1

Query:   85 PECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            P C +P+  G C+   LR+YY+   ++C  F Y GC GN NNF +LEDC+  C
Sbjct: 2731 PLCIQPVVKGSCQEAHLRYYYDRVTDSCRLFEYSGCDGNANNFGSLEDCQRLC 2783

HSP 5 Score: 60.077 bits (144), Expect = 9.565e-12
Identity = 24/53 (45.28%), Postives = 31/53 (58.49%), Query Frame = 1

Query:   88 ECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS 246
            EC      G C   F R++YN + + CE F Y GCGGN NN+ + E CE RC+
Sbjct:  422 ECVGVSLPGPCHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACEDRCA 474

HSP 6 Score: 58.9214 bits (141), Expect = 2.251e-11
Identity = 22/51 (43.14%), Postives = 33/51 (64.71%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            C  P + G CR  F+R++++ EK+ C+ F Y GC GN NNF + E+C + C
Sbjct:  728 CLHPRDSGNCRGQFVRWFFDDEKKNCDVFTYTGCQGNGNNFASKEECMAIC 778

HSP 7 Score: 56.225 bits (134), Expect = 2.151e-10
Identity = 22/51 (43.14%), Postives = 30/51 (58.82%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            C  P + G C  Y  R+++N++   CE F YG CGGN+NNF     CE +C
Sbjct: 2168 CAMPPDAGVCTNYTPRWFFNSQTGQCEQFAYGSCGGNENNFFDRNTCERKC 2218

HSP 8 Score: 45.0542 bits (105), Expect = 1.670e-6
Identity = 19/52 (36.54%), Postives = 29/52 (55.77%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS 246
            C    + G  + Y +++Y+N +   CE F + G GGN N F TL +CE  C+
Sbjct: 2232 CSFDKDSGSGKGYNVKWYFNMKNLRCEQFVFEGLGGNTNQFETLSECERICT 2283

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667211:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 69.707 bits (169), Expect = 3.993e-15
Identity = 30/56 (53.57%), Postives = 37/56 (66.07%), Query Frame = 1

Query:   76 SRAPECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            +RA  C  P E G C  Y LRFY+NA+   C+ F +GGC GN+NNF  +EDCES C
Sbjct:  534 ARATRCSLPKERGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCESAC 589

HSP 2 Score: 62.7734 bits (151), Expect = 1.193e-12
Identity = 24/62 (38.71%), Postives = 36/62 (58.06%), Query Frame = 1

Query:   58 IFKLGESRAPECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            +  + +S    C   +E+G C   F RF ++     C +F YGGCGGN NNF TL++C ++C
Sbjct:  855 VMAMKKSPVATCEADIEVGECAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKC 916

HSP 3 Score: 61.6178 bits (148), Expect = 2.623e-12
Identity = 23/53 (43.40%), Postives = 36/53 (67.92%), Query Frame = 1

Query:   88 ECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS 246
            +C +P+E G C+ +  R+Y+N +  TC  F YGGC GN+N+F T ++CE  C+
Sbjct: 1082 KCLQPVEPGPCKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECEVHCA 1134

HSP 4 Score: 60.8474 bits (146), Expect = 4.795e-12
Identity = 24/53 (45.28%), Postives = 33/53 (62.26%), Query Frame = 1

Query:   85 PECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            P C +P+  G C+   LR+YY+   ++C  F Y GC GN NNF +LEDC+  C
Sbjct: 2740 PLCIQPVVKGSCQEAHLRYYYDRVTDSCRLFEYSGCDGNANNFGSLEDCQRLC 2792

HSP 5 Score: 60.077 bits (144), Expect = 9.566e-12
Identity = 24/53 (45.28%), Postives = 31/53 (58.49%), Query Frame = 1

Query:   88 ECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS 246
            EC      G C   F R++YN + + CE F Y GCGGN NN+ + E CE RC+
Sbjct:  422 ECVGVSLPGPCHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACEDRCA 474

HSP 6 Score: 58.9214 bits (141), Expect = 2.252e-11
Identity = 22/51 (43.14%), Postives = 33/51 (64.71%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            C  P + G CR  F+R++++ EK+ C+ F Y GC GN NNF + E+C + C
Sbjct:  737 CLHPRDSGNCRGQFVRWFFDDEKKNCDVFTYTGCQGNGNNFASKEECMAIC 787

HSP 7 Score: 56.225 bits (134), Expect = 2.151e-10
Identity = 22/51 (43.14%), Postives = 30/51 (58.82%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            C  P + G C  Y  R+++N++   CE F YG CGGN+NNF     CE +C
Sbjct: 2177 CAMPPDAGVCTNYTPRWFFNSQTGQCEQFAYGSCGGNENNFFDRNTCERKC 2227

HSP 8 Score: 45.0542 bits (105), Expect = 1.670e-6
Identity = 19/52 (36.54%), Postives = 29/52 (55.77%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS 246
            C    + G  + Y +++Y+N +   CE F + G GGN N F TL +CE  C+
Sbjct: 2241 CSFDKDSGSGKGYNVKWYFNMKNLRCEQFVFEGLGGNTNQFETLSECERICT 2292

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667209:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3c.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 69.707 bits (169), Expect = 4.398e-15
Identity = 30/56 (53.57%), Postives = 37/56 (66.07%), Query Frame = 1

Query:   76 SRAPECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            +RA  C  P E G C  Y LRFY+NA+   C+ F +GGC GN+NNF  +EDCES C
Sbjct:  405 ARATRCSLPKERGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCESAC 460

HSP 2 Score: 62.7734 bits (151), Expect = 1.264e-12
Identity = 24/62 (38.71%), Postives = 36/62 (58.06%), Query Frame = 1

Query:   58 IFKLGESRAPECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            +  + +S    C   +E+G C   F RF ++     C +F YGGCGGN NNF TL++C ++C
Sbjct:  726 VMAMKKSPVATCEADIEVGECAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKC 787

HSP 3 Score: 61.6178 bits (148), Expect = 2.833e-12
Identity = 23/53 (43.40%), Postives = 36/53 (67.92%), Query Frame = 1

Query:   88 ECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS 246
            +C +P+E G C+ +  R+Y+N +  TC  F YGGC GN+N+F T ++CE  C+
Sbjct:  953 KCLQPVEPGPCKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECEVHCA 1005

HSP 4 Score: 60.8474 bits (146), Expect = 5.281e-12
Identity = 24/53 (45.28%), Postives = 33/53 (62.26%), Query Frame = 1

Query:   85 PECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            P C +P+  G C+   LR+YY+   ++C  F Y GC GN NNF +LEDC+  C
Sbjct: 2611 PLCIQPVVKGSCQEAHLRYYYDRVTDSCRLFEYSGCDGNANNFGSLEDCQRLC 2663

HSP 5 Score: 60.077 bits (144), Expect = 1.004e-11
Identity = 24/53 (45.28%), Postives = 31/53 (58.49%), Query Frame = 1

Query:   88 ECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS 246
            EC      G C   F R++YN + + CE F Y GCGGN NN+ + E CE RC+
Sbjct:  293 ECVGVSLPGPCHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACEDRCA 345

HSP 6 Score: 58.9214 bits (141), Expect = 2.480e-11
Identity = 22/51 (43.14%), Postives = 33/51 (64.71%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            C  P + G CR  F+R++++ EK+ C+ F Y GC GN NNF + E+C + C
Sbjct:  608 CLHPRDSGNCRGQFVRWFFDDEKKNCDVFTYTGCQGNGNNFASKEECMAIC 658

HSP 7 Score: 56.225 bits (134), Expect = 2.301e-10
Identity = 22/51 (43.14%), Postives = 30/51 (58.82%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            C  P + G C  Y  R+++N++   CE F YG CGGN+NNF     CE +C
Sbjct: 2048 CAMPPDAGVCTNYTPRWFFNSQTGQCEQFAYGSCGGNENNFFDRNTCERKC 2098

HSP 8 Score: 45.0542 bits (105), Expect = 1.769e-6
Identity = 19/52 (36.54%), Postives = 29/52 (55.77%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS 246
            C    + G  + Y +++Y+N +   CE F + G GGN N F TL +CE  C+
Sbjct: 2112 CSFDKDSGSGKGYNVKWYFNMKNLRCEQFVFEGLGGNTNQFETLSECERICT 2163

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667209:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3h.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 68.9366 bits (167), Expect = 8.744e-15
Identity = 30/56 (53.57%), Postives = 37/56 (66.07%), Query Frame = 1

Query:   76 SRAPECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            +RA  C  P E G C  Y LRFY+NA+   C+ F +GGC GN+NNF  +EDCES C
Sbjct:  313 ARATRCSLPKERGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCESAC 368

HSP 2 Score: 62.003 bits (149), Expect = 2.325e-12
Identity = 24/62 (38.71%), Postives = 36/62 (58.06%), Query Frame = 1

Query:   58 IFKLGESRAPECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            +  + +S    C   +E+G C   F RF ++     C +F YGGCGGN NNF TL++C ++C
Sbjct:  634 VMAMKKSPVATCEADIEVGECAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKC 695

HSP 3 Score: 60.8474 bits (146), Expect = 5.063e-12
Identity = 23/53 (43.40%), Postives = 36/53 (67.92%), Query Frame = 1

Query:   88 ECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS 246
            +C +P+E G C+ +  R+Y+N +  TC  F YGGC GN+N+F T ++CE  C+
Sbjct:  861 KCLQPVEPGPCKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECEVHCA 913

HSP 4 Score: 60.077 bits (144), Expect = 9.527e-12
Identity = 24/53 (45.28%), Postives = 33/53 (62.26%), Query Frame = 1

Query:   85 PECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            P C +P+  G C+   LR+YY+   ++C  F Y GC GN NNF +LEDC+  C
Sbjct: 2138 PLCIQPVVKGSCQEAHLRYYYDRVTDSCRLFEYSGCDGNANNFGSLEDCQRLC 2190

HSP 5 Score: 59.3066 bits (142), Expect = 1.828e-11
Identity = 24/53 (45.28%), Postives = 31/53 (58.49%), Query Frame = 1

Query:   88 ECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS 246
            EC      G C   F R++YN + + CE F Y GCGGN NN+ + E CE RC+
Sbjct:  201 ECVGVSLPGPCHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACEDRCA 253

HSP 6 Score: 58.151 bits (139), Expect = 4.220e-11
Identity = 22/51 (43.14%), Postives = 33/51 (64.71%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            C  P + G CR  F+R++++ EK+ C+ F Y GC GN NNF + E+C + C
Sbjct:  516 CLHPRDSGNCRGQFVRWFFDDEKKNCDVFTYTGCQGNGNNFASKEECMAIC 566

HSP 7 Score: 55.4546 bits (132), Expect = 3.916e-10
Identity = 22/51 (43.14%), Postives = 30/51 (58.82%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            C  P + G C  Y  R+++N++   CE F YG CGGN+NNF     CE +C
Sbjct: 1575 CAMPPDAGVCTNYTPRWFFNSQTGQCEQFAYGSCGGNENNFFDRNTCERKC 1625

HSP 8 Score: 44.669 bits (104), Expect = 2.652e-6
Identity = 19/52 (36.54%), Postives = 29/52 (55.77%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS 246
            C    + G  + Y +++Y+N +   CE F + G GGN N F TL +CE  C+
Sbjct: 1639 CSFDKDSGSGKGYNVKWYFNMKNLRCEQFVFEGLGGNTNQFETLSECERICT 1690

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667211:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3e.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 68.9366 bits (167), Expect = 8.749e-15
Identity = 30/56 (53.57%), Postives = 37/56 (66.07%), Query Frame = 1

Query:   76 SRAPECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            +RA  C  P E G C  Y LRFY+NA+   C+ F +GGC GN+NNF  +EDCES C
Sbjct:  534 ARATRCSLPKERGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCESAC 589

HSP 2 Score: 62.003 bits (149), Expect = 2.326e-12
Identity = 24/62 (38.71%), Postives = 36/62 (58.06%), Query Frame = 1

Query:   58 IFKLGESRAPECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            +  + +S    C   +E+G C   F RF ++     C +F YGGCGGN NNF TL++C ++C
Sbjct:  855 VMAMKKSPVATCEADIEVGECAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKC 916

HSP 3 Score: 60.8474 bits (146), Expect = 5.066e-12
Identity = 23/53 (43.40%), Postives = 36/53 (67.92%), Query Frame = 1

Query:   88 ECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS 246
            +C +P+E G C+ +  R+Y+N +  TC  F YGGC GN+N+F T ++CE  C+
Sbjct: 1082 KCLQPVEPGPCKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECEVHCA 1134

HSP 4 Score: 60.077 bits (144), Expect = 9.533e-12
Identity = 24/53 (45.28%), Postives = 33/53 (62.26%), Query Frame = 1

Query:   85 PECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            P C +P+  G C+   LR+YY+   ++C  F Y GC GN NNF +LEDC+  C
Sbjct: 2214 PLCIQPVVKGSCQEAHLRYYYDRVTDSCRLFEYSGCDGNANNFGSLEDCQRLC 2266

HSP 5 Score: 59.3066 bits (142), Expect = 1.829e-11
Identity = 24/53 (45.28%), Postives = 31/53 (58.49%), Query Frame = 1

Query:   88 ECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS 246
            EC      G C   F R++YN + + CE F Y GCGGN NN+ + E CE RC+
Sbjct:  422 ECVGVSLPGPCHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACEDRCA 474

HSP 6 Score: 58.151 bits (139), Expect = 4.223e-11
Identity = 22/51 (43.14%), Postives = 33/51 (64.71%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            C  P + G CR  F+R++++ EK+ C+ F Y GC GN NNF + E+C + C
Sbjct:  737 CLHPRDSGNCRGQFVRWFFDDEKKNCDVFTYTGCQGNGNNFASKEECMAIC 787

HSP 7 Score: 55.4546 bits (132), Expect = 3.918e-10
Identity = 22/51 (43.14%), Postives = 30/51 (58.82%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            C  P + G C  Y  R+++N++   CE F YG CGGN+NNF     CE +C
Sbjct: 1651 CAMPPDAGVCTNYTPRWFFNSQTGQCEQFAYGSCGGNENNFFDRNTCERKC 1701

HSP 8 Score: 44.669 bits (104), Expect = 2.654e-6
Identity = 19/52 (36.54%), Postives = 29/52 (55.77%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS 246
            C    + G  + Y +++Y+N +   CE F + G GGN N F TL +CE  C+
Sbjct: 1715 CSFDKDSGSGKGYNVKWYFNMKNLRCEQFVFEGLGGNTNQFETLSECERICT 1766

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Fly
Match: CG3604 (gene:FBgn0031562 transcript:FBtr0077545)

HSP 1 Score: 69.707 bits (169), Expect = 2.263e-16
Identity = 28/52 (53.85%), Postives = 36/52 (69.23%), Query Frame = 1

Query:   88 ECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            +C++P E GRC A F R+ YN + ++CE F YGGC GNKNNF + E CE  C
Sbjct:   54 DCHQPKETGRCFALFYRYAYNVDTQSCEEFVYGGCAGNKNNFESKEQCEQAC 105

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Fly
Match: CG3604 (gene:FBgn0031562 transcript:FBtr0346581)

HSP 1 Score: 69.707 bits (169), Expect = 2.263e-16
Identity = 28/52 (53.85%), Postives = 36/52 (69.23%), Query Frame = 1

Query:   88 ECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            +C++P E GRC A F R+ YN + ++CE F YGGC GNKNNF + E CE  C
Sbjct:   54 DCHQPKETGRCFALFYRYAYNVDTQSCEEFVYGGCAGNKNNFESKEQCEQAC 105

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Fly
Match: CG10031 (gene:FBgn0031563 transcript:FBtr0077544)

HSP 1 Score: 63.1586 bits (152), Expect = 7.206e-14
Identity = 25/53 (47.17%), Postives = 34/53 (64.15%), Query Frame = 1

Query:   85 PECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            P+C +P+++G CR    RFYYN + + CETF YGGC GN N +   + CE  C
Sbjct:   73 PKCLQPLDVGPCRMSLERFYYNKDSKACETFKYGGCRGNDNRWGFRQTCEEAC 125

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Fly
Match: CG2816 (gene:FBgn0031564 transcript:FBtr0300299)

HSP 1 Score: 54.6842 bits (130), Expect = 5.108e-11
Identity = 27/55 (49.09%), Postives = 30/55 (54.55%), Query Frame = 1

Query:   79 RAPECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            R   C +PM  GRC  Y   + YN  K  CE F YGGCGGN N F T  +CE  C
Sbjct:   27 RVKLCLQPMISGRCFGYVESYAYNPIKRHCEPFIYGGCGGNDNRFSTKAECEFNC 81

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Fly
Match: CG42828 (gene:FBgn0262010 transcript:FBtr0303835)

HSP 1 Score: 54.299 bits (129), Expect = 9.753e-11
Identity = 24/78 (30.77%), Postives = 44/78 (56.41%), Query Frame = 1

Query:   13 KIMKSTLALILLICAIFKLGESRAPECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS 246
            K++   L L+ ++ +  +  E R   CY P E G+C  + + + ++ +++ C  F +  CGGN+N F T E+CE  C+
Sbjct:    2 KLLTQFLCLLAVLLSTVESAEKRKAFCYLPYEFGKCGGHRIMWAFSNKEQECVPFVFSNCGGNENRFYTKENCEKACA 79

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Zebrafish
Match: appa (amyloid beta (A4) precursor protein a [Source:ZFIN;Acc:ZDB-GENE-000616-13])

HSP 1 Score: 63.5438 bits (153), Expect = 8.816e-13
Identity = 28/55 (50.91%), Postives = 33/55 (60.00%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS*VF 255
            C+   E G CRA   R+YY  E+  C  F YGGCGGN+NNF + E C S CS V 
Sbjct:  293 CFASAETGPCRAMLSRWYYVREERRCAPFIYGGCGGNRNNFESEEYCLSVCSGVL 347

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Zebrafish
Match: appb (amyloid beta (A4) precursor protein b [Source:ZFIN;Acc:ZDB-GENE-020220-1])

HSP 1 Score: 62.7734 bits (151), Expect = 1.595e-12
Identity = 25/52 (48.08%), Postives = 33/52 (63.46%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS 246
            C+ P   G C A   R+Y+ AEK  C +F +GGCGGN+NNF + E C + CS
Sbjct:  306 CWAPARSGPCHAKLPRWYFVAEKGRCASFTFGGCGGNRNNFESEEYCMAVCS 357

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Zebrafish
Match: appb (amyloid beta (A4) precursor protein b [Source:ZFIN;Acc:ZDB-GENE-020220-1])

HSP 1 Score: 62.7734 bits (151), Expect = 1.596e-12
Identity = 25/52 (48.08%), Postives = 33/52 (63.46%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS 246
            C+ P   G C A   R+Y+ AEK  C +F +GGCGGN+NNF + E C + CS
Sbjct:  294 CWAPARSGPCHAKLPRWYFVAEKGRCASFTFGGCGGNRNNFESEEYCMAVCS 345

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Zebrafish
Match: appb (amyloid beta (A4) precursor protein b [Source:ZFIN;Acc:ZDB-GENE-020220-1])

HSP 1 Score: 62.7734 bits (151), Expect = 1.596e-12
Identity = 25/52 (48.08%), Postives = 33/52 (63.46%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS 246
            C+ P   G C A   R+Y+ AEK  C +F +GGCGGN+NNF + E C + CS
Sbjct:  295 CWAPARSGPCHAKLPRWYFVAEKGRCASFTFGGCGGNRNNFESEEYCMAVCS 346

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Zebrafish
Match: appb (amyloid beta (A4) precursor protein b [Source:ZFIN;Acc:ZDB-GENE-020220-1])

HSP 1 Score: 62.7734 bits (151), Expect = 1.598e-12
Identity = 25/52 (48.08%), Postives = 33/52 (63.46%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS 246
            C+ P   G C A   R+Y+ AEK  C +F +GGCGGN+NNF + E C + CS
Sbjct:  306 CWAPARSGPCHAKLPRWYFVAEKGRCASFTFGGCGGNRNNFESEEYCMAVCS 357

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Xenopus
Match: rlbp1 (retinaldehyde binding protein 1 [Source:Xenbase;Acc:XB-GENE-976303])

HSP 1 Score: 63.929 bits (154), Expect = 9.156e-13
Identity = 25/51 (49.02%), Postives = 32/51 (62.75%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            C+ P ++GRCR  F R+Y+N E   C  F YGGC  NKNN+  +EDC   C
Sbjct:  240 CFAPHKVGRCRGSFTRWYFNPETNDCLEFTYGGCKPNKNNYLRIEDCRQTC 290

HSP 2 Score: 55.4546 bits (132), Expect = 1.079e-9
Identity = 27/61 (44.26%), Postives = 33/61 (54.10%), Query Frame = 1

Query:   61 FKLGESRAPECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            F++  S+A  C +  + G CRA F RFYY+     C  F YGGC GN NNF    DC   C
Sbjct:  366 FEIPNSKA-RCVDLPDTGPCRASFSRFYYDPNIRKCLRFTYGGCAGNDNNFHRESDCMRYC 425

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Xenopus
Match: rlbp1 (retinaldehyde binding protein 1 [Source:Xenbase;Acc:XB-GENE-976303])

HSP 1 Score: 63.929 bits (154), Expect = 9.383e-13
Identity = 25/51 (49.02%), Postives = 32/51 (62.75%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            C+ P ++GRCR  F R+Y+N E   C  F YGGC  NKNN+  +EDC   C
Sbjct:  240 CFAPHKVGRCRGSFTRWYFNPETNDCLEFTYGGCKPNKNNYLRIEDCRQTC 290

HSP 2 Score: 55.0694 bits (131), Expect = 1.096e-9
Identity = 27/61 (44.26%), Postives = 33/61 (54.10%), Query Frame = 1

Query:   61 FKLGESRAPECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            F++  S+A  C +  + G CRA F RFYY+     C  F YGGC GN NNF    DC   C
Sbjct:  366 FEIPNSKA-RCVDLPDTGPCRASFSRFYYDPNIRKCLRFTYGGCAGNDNNFHRESDCMRYC 425

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Xenopus
Match: rlbp1 (retinaldehyde binding protein 1 [Source:Xenbase;Acc:XB-GENE-976303])

HSP 1 Score: 63.929 bits (154), Expect = 9.388e-13
Identity = 25/51 (49.02%), Postives = 32/51 (62.75%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            C+ P ++GRCR  F R+Y+N E   C  F YGGC  NKNN+  +EDC   C
Sbjct:  240 CFAPHKVGRCRGSFTRWYFNPETNDCLEFTYGGCKPNKNNYLRIEDCRQTC 290

HSP 2 Score: 53.9138 bits (128), Expect = 3.626e-9
Identity = 24/51 (47.06%), Postives = 27/51 (52.94%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            C +  + G CRA F RFYY+     C  F YGGC GN NNF    DC   C
Sbjct:  358 CVDLPDTGPCRASFSRFYYDPNIRKCLRFTYGGCAGNDNNFHRESDCMRYC 408

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Xenopus
Match: tfpi2 (tissue factor pathway inhibitor 2 [Source:NCBI gene;Acc:548483])

HSP 1 Score: 62.3882 bits (150), Expect = 1.509e-12
Identity = 31/65 (47.69%), Postives = 37/65 (56.92%), Query Frame = 1

Query:   52 CAIFKLGESRAPE-CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            C  F      AP  CY P + G C A   R+Y+N E + CE F Y GCGGN NNF  +EDC+S C
Sbjct:  135 CMDFCSPRRDAPSFCYSPKDEGSCSASVTRYYFNIESKACEEFVYTGCGGNSNNFVKMEDCDSVC 199

HSP 2 Score: 56.225 bits (134), Expect = 2.475e-10
Identity = 27/75 (36.00%), Postives = 40/75 (53.33%), Query Frame = 1

Query:   19 MKSTLALILLICAIFKLGESRAPECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            +++ +A  LLI       +     C  P + G C+A    +YY+   +TC+ F YGGC GN N F ++EDCE  C
Sbjct:    5 LQALMAASLLIQVFGSPMQGNTTVCLLPPDEGPCKALIPHYYYDRYTQTCQEFLYGGCDGNSNKFLSMEDCEKFC 79

HSP 3 Score: 45.8246 bits (107), Expect = 1.795e-6
Identity = 23/50 (46.00%), Postives = 28/50 (56.00%), Query Frame = 1

Query:   97 EPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS 246
            +P E G CR +  R+ YN +   CE F YGGC GN NNF+    C   CS
Sbjct:   92 DPDE-GPCRGFLKRYAYNMQTMKCEQFYYGGCYGNDNNFKDKASCMDFCS 140

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Xenopus
Match: itch (itchy E3 ubiquitin protein ligase [Source:Xenbase;Acc:XB-GENE-976485])

HSP 1 Score: 63.5438 bits (153), Expect = 1.537e-12
Identity = 26/58 (44.83%), Postives = 37/58 (63.79%), Query Frame = 1

Query:   73 ESRAPE-CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            ++  PE C    E G CR + L++YY+ E ++C  F YGGCGGN+N F T ++CE  C
Sbjct: 3002 QTTGPEVCNLQKEEGTCRDFVLKWYYDPETKSCARFWYGGCGGNENRFSTQKECEKIC 3059

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Mouse
Match: Spint3 (serine peptidase inhibitor, Kunitz type, 3 [Source:MGI Symbol;Acc:MGI:3651470])

HSP 1 Score: 64.6994 bits (156), Expect = 1.123e-14
Identity = 28/58 (48.28%), Postives = 39/58 (67.24%), Query Frame = 1

Query:   73 ESRAPECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS 246
            +S  P C  P +IG CRA F+R+YYN++   CE F YGGC GN+NNF +   C++ C+
Sbjct:   29 KSLPPMCILPKDIGGCRAVFVRWYYNSKTGKCEWFRYGGCKGNENNFPSRSQCQAVCT 86

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Mouse
Match: Spint5 (serine protease inhibitor, Kunitz type 5 [Source:MGI Symbol;Acc:MGI:3651687])

HSP 1 Score: 57.3806 bits (137), Expect = 1.261e-11
Identity = 29/65 (44.62%), Postives = 39/65 (60.00%), Query Frame = 1

Query:   49 ICAIFKLGESRAPECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            +C    LG  R   C +P++ G C   F R+Y+N E   CE+F + GCGGN+NNF+T   CE RC
Sbjct:   36 LCESGHLGAKRI-ICNQPVKKGFCSFTFYRYYFNPESALCESFIFTGCGGNRNNFKTKYLCEVRC 99

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Mouse
Match: Eppin (epididymal peptidase inhibitor [Source:MGI Symbol;Acc:MGI:1922776])

HSP 1 Score: 57.7658 bits (138), Expect = 1.387e-11
Identity = 27/68 (39.71%), Postives = 39/68 (57.35%), Query Frame = 1

Query:   52 CAIFKLGE----SRAPECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            C +F  G+     +   C  P + G C AYF R+++N E  TC+ F YGGC GN NNF++   C++ C
Sbjct:   60 CCVFNCGKKCLNPQQDICSLPKDSGYCMAYFRRWWFNKENSTCQVFIYGGCQGNNNNFQSQSICQNAC 127

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Mouse
Match: Tfpi2 (tissue factor pathway inhibitor 2 [Source:MGI Symbol;Acc:MGI:108543])

HSP 1 Score: 57.3806 bits (137), Expect = 1.443e-11
Identity = 26/51 (50.98%), Postives = 32/51 (62.75%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            C  P + G C A   RFY+N+  +TCETF Y GCGGN+NNF  L+ C   C
Sbjct:   38 CSSPKDEGLCSANVTRFYFNSRNKTCETFTYTGCGGNENNFYYLDACHRAC 88

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Mouse
Match: Spint5 (serine protease inhibitor, Kunitz type 5 [Source:MGI Symbol;Acc:MGI:3651687])

HSP 1 Score: 56.9954 bits (136), Expect = 1.531e-11
Identity = 25/51 (49.02%), Postives = 34/51 (66.67%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            C +P++ G C   F R+Y+N E   CE+F + GCGGN+NNF+T   CE RC
Sbjct:   49 CNQPVKKGFCSFTFYRYYFNPESALCESFIFTGCGGNRNNFKTKYLCEVRC 99

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. UniProt/SwissProt
Match: sp|P0DN13|VKT9_ANEVI (U-actitoxin-Avd3l OS=Anemonia viridis OX=51769 PE=3 SV=1)

HSP 1 Score: 74.7146 bits (182), Expect = 6.445e-18
Identity = 35/71 (49.30%), Postives = 44/71 (61.97%), Query Frame = 1

Query:   37 LILLICAIFKLGESRA--PECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            ++ L+C       S     +C  PM++GRCRA F R+YYN+    CE F YGGCGGN NNF TLE+CE  C
Sbjct:    1 MVFLLCFFLVADVSYGINKDCLLPMDVGRCRARFPRYYYNSSSRRCEKFNYGGCGGNANNFHTLEECEKVC 71

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. UniProt/SwissProt
Match: sp|P0DN19|VKTF_ANEVI (U-actitoxin-Avd3r (Fragment) OS=Anemonia viridis OX=51769 PE=2 SV=1)

HSP 1 Score: 70.8626 bits (172), Expect = 1.613e-16
Identity = 31/52 (59.62%), Postives = 37/52 (71.15%), Query Frame = 1

Query:   88 ECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            +C  PM++GRCRA F R+YYN+    CE F YGGC GN NNF TLE+CE  C
Sbjct:   10 DCLLPMDVGRCRAKFPRYYYNSSSRRCEKFNYGGCRGNANNFHTLEECEKVC 61

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. UniProt/SwissProt
Match: sp|P0DMW7|VKT3B_ACTEQ (PI-actitoxin-Aeq3b OS=Actinia equina OX=6106 PE=1 SV=1)

HSP 1 Score: 69.707 bits (169), Expect = 3.213e-16
Identity = 30/51 (58.82%), Postives = 36/51 (70.59%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            C  P  +G+CR YF RFYYN E   C+ F YGGCGGN+NNF T+EDC + C
Sbjct:    6 CQLPAVVGKCRGYFPRFYYNTEAGKCQQFIYGGCGGNRNNFETVEDCRATC 56

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. UniProt/SwissProt
Match: sp|P0DN06|VKT1A_ANEVI (U-actitoxin-Avd3f OS=Anemonia viridis OX=51769 PE=3 SV=1)

HSP 1 Score: 69.3218 bits (168), Expect = 1.105e-15
Identity = 33/71 (46.48%), Postives = 43/71 (60.56%), Query Frame = 1

Query:   37 LILLICAIFKLGESRA--PECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            ++ L+C       S     +C  PM++GRCRA   R+YYN+  + CE F YGGC GN NNF TLE+CE  C
Sbjct:    1 MVFLLCFFLVADVSYGINKDCLLPMDVGRCRASHPRYYYNSSSKRCEKFIYGGCRGNANNFHTLEECEKVC 71

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. UniProt/SwissProt
Match: sp|P0DMW6|VKT3A_ACTEQ (PI-actitoxin-Aeq3a OS=Actinia equina OX=6106 PE=1 SV=1)

HSP 1 Score: 68.1662 bits (165), Expect = 1.313e-15
Identity = 29/51 (56.86%), Postives = 36/51 (70.59%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            C  P  +G+CR YF R+YYN E   C+ F YGGCGGN+NNF T+EDC + C
Sbjct:    6 CQLPAVVGKCRGYFPRYYYNTEAGKCQQFIYGGCGGNRNNFETVEDCRATC 56

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. TrEMBL
Match: C8YJ94 (Serine protease inhibitor 2 OS=Tabanus yao OX=485572 PE=2 SV=1)

HSP 1 Score: 78.1814 bits (191), Expect = 6.738e-17
Identity = 34/74 (45.95%), Postives = 50/74 (67.57%), Query Frame = 1

Query:   28 TLALILLICAIFKL-GESRAPECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS 246
             L+LI +I ++  L   ++ P C +P  +GRC A F +FYYN+    C+ F YGGCGGN+NNF TLE+C ++C+
Sbjct:    3 VLSLIFVIFSVLVLFASAKDPVCDQPKAVGRCFAAFPKFYYNSSSGQCQAFIYGGCGGNENNFNTLEECNAKCA 76

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. TrEMBL
Match: A0A1D2MN35 (Kunitz-type serine protease inhibitor kalicludine-1 OS=Orchesella cincta OX=48709 GN=Ocin01_12432 PE=4 SV=1)

HSP 1 Score: 78.5666 bits (192), Expect = 7.003e-17
Identity = 34/71 (47.89%), Postives = 46/71 (64.79%), Query Frame = 1

Query:   34 ALILLICAIFKLGESRAPECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS 246
            A+++L CA      +    C +PME G CRA   RFYYN+E + CE F YGGC  N+NNF+T+E+CE  C+
Sbjct:   11 AMLILFCANSASAAALEDSCQQPMERGTCRAMHARFYYNSETKKCEKFNYGGCKKNQNNFKTMEECEKACA 81

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. TrEMBL
Match: C8YJ95 (Serine protease inhibitor 3 OS=Tabanus yao OX=485572 PE=2 SV=1)

HSP 1 Score: 77.7962 bits (190), Expect = 1.089e-16
Identity = 34/74 (45.95%), Postives = 50/74 (67.57%), Query Frame = 1

Query:   28 TLALILLICAIFKL-GESRAPECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS 246
             L+LI +I ++  L   ++ P C +P  +GRC A F +FY+N+    CE F YGGCGGN+NNF TLE+C ++C+
Sbjct:    3 VLSLIFVIFSVLVLFASAKDPVCDQPKAVGRCFAAFPKFYFNSSSGQCEAFIYGGCGGNENNFSTLEECNAKCA 76

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. TrEMBL
Match: C1IBY4 (Tabserpin OS=Tabanus yao OX=485572 PE=2 SV=1)

HSP 1 Score: 76.6406 bits (187), Expect = 2.910e-16
Identity = 33/74 (44.59%), Postives = 50/74 (67.57%), Query Frame = 1

Query:   28 TLALILLICAIFKL-GESRAPECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS 246
             L+LI ++ ++  L   ++ P C +P  +GRC A F +FY+N+    CE F YGGCGGN+NNF TLE+C ++C+
Sbjct:    3 VLSLIFVLFSVLVLFASAKDPVCDQPKAVGRCFAAFPKFYFNSSSGQCEAFIYGGCGGNENNFNTLEECNAKCA 76

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. TrEMBL
Match: C8YJ96 (Serine protease inhibitor 4 OS=Tabanus yao OX=485572 PE=2 SV=1)

HSP 1 Score: 75.0998 bits (183), Expect = 1.356e-15
Identity = 33/74 (44.59%), Postives = 49/74 (66.22%), Query Frame = 1

Query:   28 TLALILLICAIFKL-GESRAPECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS 246
             L+LI +I ++  L   ++ P C +P  +GRC A F +FY+N+     E F YGGCGGN+NNF TLE+C ++C+
Sbjct:    3 VLSLIFVIFSVLVLFASAKDPVCDQPKAVGRCFAAFPKFYFNSSSAQGEAFFYGGCGGNENNFNTLEECNAKCA 76

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BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Cavefish
Match: appb (amyloid beta A4 protein-like [Source:NCBI gene;Acc:103046668])

HSP 1 Score: 62.003 bits (149), Expect = 2.980e-12
Identity = 25/52 (48.08%), Postives = 32/52 (61.54%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS 246
            C+ P   G CRA   R+Y+ AE   C  F +GGCGGN+NNF + E C + CS
Sbjct:  311 CWAPPRRGPCRATLSRWYFVAETGRCAPFSFGGCGGNRNNFESEEYCMAVCS 362

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Cavefish
Match: appb (amyloid beta A4 protein-like [Source:NCBI gene;Acc:103046668])

HSP 1 Score: 62.003 bits (149), Expect = 3.032e-12
Identity = 25/52 (48.08%), Postives = 32/52 (61.54%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS 246
            C+ P   G CRA   R+Y+ AE   C  F +GGCGGN+NNF + E C + CS
Sbjct:  311 CWAPPRRGPCRATLSRWYFVAETGRCAPFSFGGCGGNRNNFESEEYCMAVCS 362

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Cavefish
Match: col28a2b (collagen, type XXVIII, alpha 2b [Source:ZFIN;Acc:ZDB-GENE-130530-762])

HSP 1 Score: 62.003 bits (149), Expect = 3.052e-12
Identity = 23/53 (43.40%), Postives = 32/53 (60.38%), Query Frame = 1

Query:   85 PECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            P C   ++ G CR Y +R+YY+ +   C  F YGGC GN+N F T E+C+  C
Sbjct: 1081 PRCELTLDQGPCREYNIRWYYDKQANACAQFWYGGCDGNRNRFDTEEECKKTC 1133

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BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Cavefish
Match: ENSAMXT00000056342.1 (pep primary_assembly:Astyanax_mexicanus-2.0:25:41015233:41016395:-1 gene:ENSAMXG00000036709.1 transcript:ENSAMXT00000056342.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 58.151 bits (139), Expect = 3.969e-12
Identity = 26/76 (34.21%), Postives = 44/76 (57.89%), Query Frame = 1

Query:   16 IMKSTLALILLICAIFKLGESRAPECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            I  +  A++  I ++ +L       C  P ++G+C  + L+++++   + C  F YGGCGGN N F T E+CE+RC
Sbjct:   16 ISGTAAAMVTAIASLQRL----TLHCKLPHDLGKCYNFALKWHFDTSIQECTRFWYGGCGGNGNRFETQEECEARC 87

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Cavefish
Match: ENSAMXT00000039940.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000999.1:23065:40314:1 gene:ENSAMXG00000037874.1 transcript:ENSAMXT00000039940.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 60.4622 bits (145), Expect = 1.102e-11
Identity = 23/51 (45.10%), Postives = 31/51 (60.78%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            C  P E G C  + L+++Y++   +C  F YGGCGGN N F T E+CE  C
Sbjct:  438 CKLPKEEGTCIKFVLKWFYDSVSNSCTRFWYGGCGGNLNRFNTQEECEKEC 488

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Sea Lamprey
Match: tfpi2 (tissue factor pathway inhibitor 2 [Source:ZFIN;Acc:ZDB-GENE-060503-38])

HSP 1 Score: 58.151 bits (139), Expect = 8.532e-12
Identity = 27/63 (42.86%), Postives = 39/63 (61.90%), Query Frame = 1

Query:   58 IFKLGESRAPECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS 246
            +F L + R   C  P + G CRA F R+++N     CE+F YGGC  N+NNF T+++C + CS
Sbjct:   17 VFTLEDQRV-TCTLPAKPGDCRAAFPRYFFNRSTLRCESFIYGGCHSNENNFETMQECRAACS 78

HSP 2 Score: 55.8398 bits (133), Expect = 4.436e-11
Identity = 25/52 (48.08%), Postives = 31/52 (59.62%), Query Frame = 1

Query:   88 ECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            EC    + G C+  F RFYYN +K +C  F Y GCGGN NNF + + C S C
Sbjct:  146 ECLSRHDTGNCQGNFRRFYYNIQKRSCLPFSYSGCGGNNNNFISAKTCLSTC 197

HSP 3 Score: 52.7582 bits (125), Expect = 7.610e-10
Identity = 24/51 (47.06%), Postives = 28/51 (54.90%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            C    E GRCRA+  R++YN     C  F YGGCGGN N F  +E C   C
Sbjct:   87 CRPDAETGRCRAHITRYFYNMTLGMCMPFVYGGCGGNNNRFEDMESCVFSC 137

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005043.1 (pep scaffold:Pmarinus_7.0:GL481015:31246:35903:1 gene:ENSPMAG00000004579.1 transcript:ENSPMAT00000005043.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 55.4546 bits (132), Expect = 5.901e-11
Identity = 24/53 (45.28%), Postives = 33/53 (62.26%), Query Frame = 1

Query:   88 ECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS 246
             C   ++ G CRAY  R +YN   + CE F YGGC GN NNF +L +C ++C+
Sbjct:    2 SCMMDLDPGPCRAYLPRVFYNRYTQRCEPFHYGGCFGNGNNFESLAECNAKCA 54

HSP 2 Score: 54.299 bits (129), Expect = 1.908e-10
Identity = 26/55 (47.27%), Postives = 33/55 (60.00%), Query Frame = 1

Query:   82 APE-CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            AP+ C   ME+G CRA   R+++N    +CE FGYGGC GN NNF+    C   C
Sbjct:   70 APKACRLDMEVGVCRALLRRYFFNMTSGSCEEFGYGGCQGNLNNFKDAASCYQHC 124

HSP 3 Score: 53.1434 bits (126), Expect = 4.577e-10
Identity = 24/51 (47.06%), Postives = 29/51 (56.86%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            C    + G C A   RF+YN +   CE+F YGGCGGN NNF +   C S C
Sbjct:  166 CLMKADPGECTAVIPRFHYNPKTSNCESFTYGGCGGNDNNFSSERSCMSVC 216

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005038.1 (pep scaffold:Pmarinus_7.0:GL481015:31246:35903:1 gene:ENSPMAG00000004579.1 transcript:ENSPMAT00000005038.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 55.4546 bits (132), Expect = 7.009e-11
Identity = 24/53 (45.28%), Postives = 33/53 (62.26%), Query Frame = 1

Query:   88 ECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS 246
             C   ++ G CRAY  R +YN   + CE F YGGC GN NNF +L +C ++C+
Sbjct:    2 SCMMDLDPGPCRAYLPRVFYNRYTQRCEPFHYGGCFGNGNNFESLAECNAKCA 54

HSP 2 Score: 54.299 bits (129), Expect = 1.847e-10
Identity = 26/55 (47.27%), Postives = 33/55 (60.00%), Query Frame = 1

Query:   82 APE-CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            AP+ C   ME+G CRA   R+++N    +CE FGYGGC GN NNF+    C   C
Sbjct:   71 APKACRLDMEVGVCRALLRRYFFNMTSGSCEEFGYGGCQGNLNNFKDAASCYQHC 125

HSP 3 Score: 52.7582 bits (125), Expect = 5.426e-10
Identity = 25/54 (46.30%), Postives = 30/54 (55.56%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS*V 252
            C    + G C A   RF+YN +   CE+F YGGCGGN NNF +   C S C  V
Sbjct:  167 CLMKADPGECTAVIPRFHYNPKTSNCESFTYGGCGGNDNNFSSERSCMSVCGQV 220

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Sea Lamprey
Match: WFIKKN1 (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30912])

HSP 1 Score: 54.6842 bits (130), Expect = 2.461e-10
Identity = 23/59 (38.98%), Postives = 35/59 (59.32%), Query Frame = 1

Query:   67 LGESRAPECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            + E  A EC+EP ++  C +   ++YY++    C+TF YGGC  N+N F T E C+  C
Sbjct:  333 IAEFPASECHEPPDVTHCGSARTKWYYDSGLNACDTFVYGGCDSNRNRFDTYEGCKRWC 391

HSP 2 Score: 46.595 bits (109), Expect = 1.540e-7
Identity = 21/51 (41.18%), Postives = 28/51 (54.90%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            C+ P   G CR +   + YN   + C+   YGGC GN+NNF + E CE  C
Sbjct:  399 CHLPPVQGPCRDWERHWAYNPLIKQCQLLVYGGCEGNENNFESREACEDNC 449

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Sea Lamprey
Match: WFIKKN1 (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30912])

HSP 1 Score: 53.5286 bits (127), Expect = 5.337e-10
Identity = 23/51 (45.10%), Postives = 34/51 (66.67%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            C  P++ G C+ + LR+ YN   + C++F YGGC GN+NNF++ E CE  C
Sbjct:  374 CSLPVQQGPCKQWALRWAYNPLIKRCQSFIYGGCEGNENNFQSQELCEDNC 424

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Nematostella
Match: EDO29819 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T2J6])

HSP 1 Score: 60.8474 bits (146), Expect = 4.811e-14
Identity = 25/51 (49.02%), Postives = 34/51 (66.67%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            C  P ++G CRA   R ++N++   CE F YGGCGGN NNF T+E+C+  C
Sbjct:   14 CTLPKKVGDCRAAMPRVFFNSQSGKCEDFIYGGCGGNANNFHTMEECKKAC 64

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Nematostella
Match: EDO41696 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3T1])

HSP 1 Score: 59.6918 bits (143), Expect = 1.318e-13
Identity = 26/52 (50.00%), Postives = 33/52 (63.46%), Query Frame = 1

Query:   88 ECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            EC +P   G CRAYF R++YN     C+ F YGGC GN NNF +  +CE +C
Sbjct:    1 ECLQPKLTGPCRAYFERWFYNQTSRKCKQFVYGGCQGNSNNFESKAECEKKC 52

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Nematostella
Match: EDO26263 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3T1])

HSP 1 Score: 59.6918 bits (143), Expect = 1.318e-13
Identity = 26/52 (50.00%), Postives = 33/52 (63.46%), Query Frame = 1

Query:   88 ECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            EC +P   G CRAYF R++YN     C+ F YGGC GN NNF +  +CE +C
Sbjct:    1 ECLQPKLTGPCRAYFERWFYNQTSRKCKQFVYGGCQGNSNNFESKAECEKKC 52

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Nematostella
Match: EDO41922 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S322])

HSP 1 Score: 55.0694 bits (131), Expect = 1.035e-11
Identity = 27/59 (45.76%), Postives = 33/59 (55.93%), Query Frame = 1

Query:   67 LGESRAPECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            +G  +   C  P   GRC AY   FYY+ ++E C+ F YGGC GN N F T E CE  C
Sbjct:    1 MGGEQPSFCSLPAVTGRCMAYIPSFYYDMKEEKCKEFIYGGCNGNLNRFDTQEKCEEAC 59

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Nematostella
Match: EDO31759 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SX08])

HSP 1 Score: 53.9138 bits (128), Expect = 2.069e-11
Identity = 25/51 (49.02%), Postives = 31/51 (60.78%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            C  P   G CRA   ++YYN ++  C  F YGGCGGN NNF T  +C+S C
Sbjct:    2 CKMPAAAGPCRAAMPQWYYNFKRHRCIRFIYGGCGGNPNNFDTKNECKSAC 52

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Medaka
Match: spint1a (kunitz-type protease inhibitor 1 [Source:NCBI gene;Acc:101175207])

HSP 1 Score: 62.7734 bits (151), Expect = 1.281e-12
Identity = 28/58 (48.28%), Postives = 35/58 (60.34%), Query Frame = 1

Query:   73 ESRAPECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS 246
            E     C  P ++G CR  F R+YYNA  E CETF +GGC  NKNN+ T E+C   C+
Sbjct:  228 EQSMDHCLVPKKVGPCRGSFPRWYYNAASEKCETFFFGGCRQNKNNYLTEEECAMACN 285

HSP 2 Score: 50.447 bits (119), Expect = 2.688e-8
Identity = 27/65 (41.54%), Postives = 34/65 (52.31%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC-----S*VFAFNNN 270
            C E  + G CR    ++YY   +E C  F Y GCGGN+N F T   C+S C     + VFA  NN
Sbjct:  358 CTETPDTGTCRESSTKWYYEPYQEDCFPFNYSGCGGNENKFDTKNYCQSFCRGVTKADVFALLNN 422

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Medaka
Match: col28a2a (collagen alpha-1(XXVIII) chain [Source:NCBI gene;Acc:101157899])

HSP 1 Score: 62.7734 bits (151), Expect = 1.542e-12
Identity = 23/53 (43.40%), Postives = 32/53 (60.38%), Query Frame = 1

Query:   85 PECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            P C   ++ G CR Y +R+YY+ +   C  F YGGCGGN+N F T  +C+  C
Sbjct:  968 PRCSITLDQGTCRDYVIRWYYDQQANACAQFWYGGCGGNENRFETESECKKTC 1020

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Medaka
Match: tfpi2 (tissue factor pathway inhibitor 2 [Source:NCBI gene;Acc:101174930])

HSP 1 Score: 61.2326 bits (147), Expect = 3.355e-12
Identity = 26/51 (50.98%), Postives = 33/51 (64.71%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            C +P++ G+C A   RFYYN   +TCE F Y GCGG+ NNF + E CE  C
Sbjct:  204 CLDPLDKGKCSASMRRFYYNKATKTCEEFAYSGCGGSSNNFVSRESCEDVC 254

HSP 2 Score: 56.225 bits (134), Expect = 2.267e-10
Identity = 27/57 (47.37%), Postives = 32/57 (56.14%), Query Frame = 1

Query:   79 RAPE-CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS 246
            + P+ C  P E G CRA F  +++N     CE F YGGCGGN N FR L  C   CS
Sbjct:  139 KVPQICRFPKEEGHCRALFPSYFFNMSTMQCEPFSYGGCGGNSNRFRDLTSCMDFCS 195

HSP 3 Score: 49.2914 bits (116), Expect = 7.309e-8
Identity = 27/73 (36.99%), Postives = 39/73 (53.42%), Query Frame = 1

Query:   40 ILLICAIFKL---GESRAPE--CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            +L + A+F     G S  P+  C   ++ G CR    R++YN   + CE F YGGC GN NNF + + C+  C
Sbjct:   62 MLTLFALFSSLPGGLSLVPKGACLLRVDEGPCRGQIERYFYNTITQKCEVFYYGGCHGNANNFMSFQKCQKTC 134

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Medaka
Match: APP (amyloid-beta A4 protein [Source:NCBI gene;Acc:101162104])

HSP 1 Score: 61.2326 bits (147), Expect = 4.825e-12
Identity = 26/55 (47.27%), Postives = 34/55 (61.82%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRCS*VF 255
            C+   E G CRA   R++++ E+  C  F YGGCGGN+NNF + E C S CS V 
Sbjct:  330 CWADAETGPCRALLPRWFFDREEGRCVQFIYGGCGGNRNNFESEEYCMSVCSSVL 384

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Medaka
Match: ENSORLT00000040309.1 (pep primary_assembly:ASM223467v1:11:20946373:20947959:-1 gene:ENSORLG00000024141.1 transcript:ENSORLT00000040309.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 56.225 bits (134), Expect = 8.150e-12
Identity = 23/51 (45.10%), Postives = 33/51 (64.71%), Query Frame = 1

Query:   91 CYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            C +P++ G CR Y +R+Y++ +  +C  F YGGC GN+NNF T E C   C
Sbjct:    8 CSQPLDPGPCRLYRVRWYFDPQANSCAQFWYGGCHGNQNNFETEEICRKAC 58

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Planmine SMEST
Match: SMESG000037994.1 (SMESG000037994.1)

HSP 1 Score: 95.5153 bits (236), Expect = 2.921e-27
Identity = 43/75 (57.33%), Postives = 52/75 (69.33%), Query Frame = 1

Query:   19 MKSTLALILLICAIFKLGESRAPECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            M S +   L+ C IF LGESRAPEC EP + G C AYF RFY+N +   CE+F YGGC  N NNF T+E+CE+RC
Sbjct:    1 MNSIVIFTLIFCVIFSLGESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 75

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Planmine SMEST
Match: SMESG000037999.1 (SMESG000037999.1)

HSP 1 Score: 81.6481 bits (200), Expect = 8.100e-22
Identity = 38/75 (50.67%), Postives = 53/75 (70.67%), Query Frame = 1

Query:   19 MKSTLALILLICAIFKLGESRAPECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            MKS + +++++ ++ +L ESR  EC EP + G C AYF RFY+N+E   CETF YGGCG N NNF+T ++CE  C
Sbjct:    1 MKSKILVLVVLFSLSQLLESRLKECNEPKQSGMCEAYFKRFYFNSETGKCETFIYGGCGKNGNNFQTEDECEELC 75

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Planmine SMEST
Match: SMESG000037999.1 (SMESG000037999.1)

HSP 1 Score: 81.6481 bits (200), Expect = 9.123e-22
Identity = 38/75 (50.67%), Postives = 53/75 (70.67%), Query Frame = 1

Query:   19 MKSTLALILLICAIFKLGESRAPECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            MKS + +++++ ++ +L ESR  EC EP + G C AYF RFY+N+E   CETF YGGCG N NNF+T ++CE  C
Sbjct:    3 MKSKILVLVVLFSLSQLLESRLKECNEPKQSGMCEAYFKRFYFNSETGKCETFIYGGCGKNGNNFQTEDECEELC 77

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Planmine SMEST
Match: SMESG000037995.1 (SMESG000037995.1)

HSP 1 Score: 81.6481 bits (200), Expect = 1.148e-21
Identity = 38/75 (50.67%), Postives = 53/75 (70.67%), Query Frame = 1

Query:   19 MKSTLALILLICAIFKLGESRAPECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            MKS + +++++ ++ +L ESR  EC EP + G C AYF RFY+N+E   CETF YGGCG N NNF+T ++CE  C
Sbjct:    3 MKSKILVLVVLFSLSQLLESRLKECNEPKQSGMCMAYFKRFYFNSETGKCETFIYGGCGKNGNNFQTEDECEELC 77

[Close]

BLAST of Kunitz-type serine protease inhibitor IX vs. Planmine SMEST
Match: SMESG000037997.1 (SMESG000037997.1)

HSP 1 Score: 73.9442 bits (180), Expect = 1.363e-18
Identity = 35/74 (47.30%), Postives = 45/74 (60.81%), Query Frame = 1

Query:   22 KSTLALILLICAIFKLGESRAPECYEPMEIGRCRAYFLRFYYNAEKETCETFGYGGCGGNKNNFRTLEDCESRC 243
            K  + L L++  I    ES  P C +P+  G C AYF R++YN   E CE F YGGCG N NNF+TL+DC+  C
Sbjct:    4 KLIIWLALVLSFIIFTIESLEPNCEDPLVKGLCEAYFPRYFYNDTSEKCERFIYGGCGANGNNFKTLKDCQDLC 77

The following BLAST results are available for this feature:

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Human
BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Celegans
BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Fly
BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Zebrafish
BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Xenopus
BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Mouse
BLAST of Kunitz-type serine protease inhibitor IX vs. UniProt/SwissProt
BLAST of Kunitz-type serine protease inhibitor IX vs. TrEMBL
BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Cavefish
BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Sea Lamprey
BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Yeast
BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Nematostella
BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Medaka
BLAST of Kunitz-type serine protease inhibitor IX vs. Planmine SMEST

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
COL7A1	2.078e-12	51.85	collagen type VII alpha 1 chain [Source:HGNC Symbo...	[more]
COL6A3	2.567e-12	42.86	collagen type VI alpha 3 chain [Source:HGNC Symbol...	[more]
COL6A3	2.567e-12	42.86	collagen type VI alpha 3 chain [Source:HGNC Symbol...	[more]
COL6A3	2.574e-12	42.86	collagen type VI alpha 3 chain [Source:HGNC Symbol...	[more]
COL6A3	2.574e-12	42.86	collagen type VI alpha 3 chain [Source:HGNC Symbol...	[more]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mlt-11	3.993e-15	53.57	pep chromosome:WBcel235:V:20667211:20678513:1 gene...	[more]
mlt-11	3.993e-15	53.57	pep chromosome:WBcel235:V:20667211:20678513:1 gene...	[more]
mlt-11	4.398e-15	53.57	pep chromosome:WBcel235:V:20667209:20678513:1 gene...	[more]
mlt-11	8.744e-15	53.57	pep chromosome:WBcel235:V:20667209:20678513:1 gene...	[more]
mlt-11	8.749e-15	53.57	pep chromosome:WBcel235:V:20667211:20678513:1 gene...	[more]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CG3604	2.263e-16	53.85	gene:FBgn0031562 transcript:FBtr0077545	[more]
CG3604	2.263e-16	53.85	gene:FBgn0031562 transcript:FBtr0346581	[more]
CG10031	7.206e-14	47.17	gene:FBgn0031563 transcript:FBtr0077544	[more]
CG2816	5.108e-11	49.09	gene:FBgn0031564 transcript:FBtr0300299	[more]
CG42828	9.753e-11	30.77	gene:FBgn0262010 transcript:FBtr0303835	[more]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
appa	8.816e-13	50.91	amyloid beta (A4) precursor protein a [Source:ZFIN...	[more]
appb	1.595e-12	48.08	amyloid beta (A4) precursor protein b [Source:ZFIN...	[more]
appb	1.596e-12	48.08	amyloid beta (A4) precursor protein b [Source:ZFIN...	[more]
appb	1.596e-12	48.08	amyloid beta (A4) precursor protein b [Source:ZFIN...	[more]
appb	1.598e-12	48.08	amyloid beta (A4) precursor protein b [Source:ZFIN...	[more]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rlbp1	9.156e-13	49.02	retinaldehyde binding protein 1 [Source:Xenbase;Ac...	[more]
rlbp1	9.383e-13	49.02	retinaldehyde binding protein 1 [Source:Xenbase;Ac...	[more]
rlbp1	9.388e-13	49.02	retinaldehyde binding protein 1 [Source:Xenbase;Ac...	[more]
tfpi2	1.509e-12	47.69	tissue factor pathway inhibitor 2 [Source:NCBI gen...	[more]
itch	1.537e-12	44.83	itchy E3 ubiquitin protein ligase [Source:Xenbase;...	[more]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Spint3	1.123e-14	48.28	serine peptidase inhibitor, Kunitz type, 3 [Source...	[more]
Spint5	1.261e-11	44.62	serine protease inhibitor, Kunitz type 5 [Source:M...	[more]
Eppin	1.387e-11	39.71	epididymal peptidase inhibitor [Source:MGI Symbol;...	[more]
Tfpi2	1.443e-11	50.98	tissue factor pathway inhibitor 2 [Source:MGI Symb...	[more]
Spint5	1.531e-11	49.02	serine protease inhibitor, Kunitz type 5 [Source:M...	[more]

BLAST of Kunitz-type serine protease inhibitor IX vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P0DN13\|VKT9_ANEVI	6.445e-18	49.30	U-actitoxin-Avd3l OS=Anemonia viridis OX=51769 PE=...	[more]
sp\|P0DN19\|VKTF_ANEVI	1.613e-16	59.62	U-actitoxin-Avd3r (Fragment) OS=Anemonia viridis O...	[more]
sp\|P0DMW7\|VKT3B_ACTEQ	3.213e-16	58.82	PI-actitoxin-Aeq3b OS=Actinia equina OX=6106 PE=1 ...	[more]
sp\|P0DN06\|VKT1A_ANEVI	1.105e-15	46.48	U-actitoxin-Avd3f OS=Anemonia viridis OX=51769 PE=...	[more]
sp\|P0DMW6\|VKT3A_ACTEQ	1.313e-15	56.86	PI-actitoxin-Aeq3a OS=Actinia equina OX=6106 PE=1 ...	[more]

BLAST of Kunitz-type serine protease inhibitor IX vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
C8YJ94	6.738e-17	45.95	Serine protease inhibitor 2 OS=Tabanus yao OX=4855...	[more]
A0A1D2MN35	7.003e-17	47.89	Kunitz-type serine protease inhibitor kalicludine-...	[more]
C8YJ95	1.089e-16	45.95	Serine protease inhibitor 3 OS=Tabanus yao OX=4855...	[more]
C1IBY4	2.910e-16	44.59	Tabserpin OS=Tabanus yao OX=485572 PE=2 SV=1	[more]
C8YJ96	1.356e-15	44.59	Serine protease inhibitor 4 OS=Tabanus yao OX=4855...	[more]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
appb	2.980e-12	48.08	amyloid beta A4 protein-like [Source:NCBI gene;Acc...	[more]
appb	3.032e-12	48.08	amyloid beta A4 protein-like [Source:NCBI gene;Acc...	[more]
col28a2b	3.052e-12	43.40	collagen, type XXVIII, alpha 2b [Source:ZFIN;Acc:Z...	[more]
ENSAMXT00000056342.1	3.969e-12	34.21	pep primary_assembly:Astyanax_mexicanus-2.0:25:410...	[more]
ENSAMXT00000039940.1	1.102e-11	45.10	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tfpi2	8.532e-12	42.86	tissue factor pathway inhibitor 2 [Source:ZFIN;Acc...	[more]
ENSPMAT00000005043.1	5.901e-11	45.28	pep scaffold:Pmarinus_7.0:GL481015:31246:35903:1 g...	[more]
ENSPMAT00000005038.1	7.009e-11	45.28	pep scaffold:Pmarinus_7.0:GL481015:31246:35903:1 g...	[more]
WFIKKN1	2.461e-10	38.98	WAP, follistatin/kazal, immunoglobulin, kunitz and...	[more]
WFIKKN1	5.337e-10	45.10	WAP, follistatin/kazal, immunoglobulin, kunitz and...	[more]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO29819	4.811e-14	49.02	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO41696	1.318e-13	50.00	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO26263	1.318e-13	50.00	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO41922	1.035e-11	45.76	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO31759	2.069e-11	49.02	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Kunitz-type serine protease inhibitor IX vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
spint1a	1.281e-12	48.28	kunitz-type protease inhibitor 1 [Source:NCBI gene...	[more]
col28a2a	1.542e-12	43.40	collagen alpha-1(XXVIII) chain [Source:NCBI gene;A...	[more]
tfpi2	3.355e-12	50.98	tissue factor pathway inhibitor 2 [Source:NCBI gen...	[more]
APP	4.825e-12	47.27	amyloid-beta A4 protein [Source:NCBI gene;Acc:1011...	[more]
ENSORLT00000040309.1	8.150e-12	45.10	pep primary_assembly:ASM223467v1:11:20946373:20947...	[more]

BLAST of Kunitz-type serine protease inhibitor IX vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000037994.1	2.921e-27	57.33	SMESG000037994.1	[more]
SMESG000037999.1	8.100e-22	50.67	SMESG000037999.1	[more]
SMESG000037999.1	9.123e-22	50.67	SMESG000037999.1	[more]
SMESG000037995.1	1.148e-21	50.67	SMESG000037995.1	[more]
SMESG000037997.1	1.363e-18	47.30	SMESG000037997.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence

transcript sequence

>SMED30021202 ID=SMED30021202|Name=Kunitz-type serine protease inhibitor IX|organism=Schmidtea mediterranea sexual|type=transcript|length=320bp
CGGCNNNANNATAAAATCATGAAATCAACATTAGCATTAATTCTTTTAAT
TTGCGCGATTTTTAAGCTTGGAGAAAGTAGAGCTCCAGAATGCTACGAGC
CAATGGAAATTGGAAGGTGTAGAGCTTATTTCCTTAGGTTTTATTATAAT
GCCGAAAAAGAGACCTGCGAAACCTTCGGCTACGGTGGATGCGGCGGAAA
TAAAAACAATTTCCGAACTCTTGAAGATTGCGAAAGTCGTTGTTCCTAAG
TATTTGCATTCAATAATAATTTAACAATAACGATTTTTATTAAATAAAAG
CAATTTGTTTTAAAAAAAAA

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **cellular component**
Term	Definition
GO:0005576	extracellular region
GO:0016020	membrane
GO:0016021	integral component of membrane

Vocabulary: **biological process**
Term	Definition
GO:0010466	negative regulation of peptidase activity
GO:0006508	proteolysis
GO:0010951	negative regulation of endopeptidase activity

Vocabulary: **molecular function**
Term	Definition
GO:0030414	peptidase inhibitor activity
GO:0090729	toxin activity
GO:0004867	serine-type endopeptidase inhibitor activity
GO:0008233	peptidase activity

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000016	pharynx
PLANA:0000025	nervous system
PLANA:0000099	neuron
PLANA:0000420	parapharyngeal region

Vocabulary: **INTERPRO**
Term	Definition
IPR036880	Kunitz_BPTI_sf
IPR002223	Kunitz_BPTI
IPR020901	Prtase_inh_Kunz-CS

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR002223	Pancreatic trypsin inhibitor Kunitz domain	PRINTS	PR00759	BASICPTASE	coord: 52..62 score: 65.64 coord: 24..38 score: 31.77 coord: 62..77 score: 48.8
IPR002223	Pancreatic trypsin inhibitor Kunitz domain	SMART	SM00131	KU_2	coord: 25..78 e-value: 2.9E-22 score: 90.0
IPR002223	Pancreatic trypsin inhibitor Kunitz domain	PFAM	PF00014	Kunitz_BPTI	coord: 27..77 e-value: 1.1E-18 score: 67.1
IPR002223	Pancreatic trypsin inhibitor Kunitz domain	PROSITE	PS50279	BPTI_KUNITZ_2	coord: 27..77 score: 15.637
IPR002223	Pancreatic trypsin inhibitor Kunitz domain	CDD	cd00109	KU	coord: 27..77 e-value: 9.7839E-23 score: 79.9866
IPR036880	Pancreatic trypsin inhibitor Kunitz domain superfamily	GENE3D	G3DSA:4.10.410.10		coord: 23..78 e-value: 2.7E-22 score: 80.3
IPR036880	Pancreatic trypsin inhibitor Kunitz domain superfamily	SUPERFAMILY	SSF57362	BPTI-like	coord: 22..77
None	No IPR available	PANTHER	PTHR10083	KUNITZ-TYPE PROTEASE INHIBITOR-RELATED	coord: 24..77
None	No IPR available	SIGNALP_EUK	SignalP-noTM	SignalP-noTM	coord: 1..22 score: 0.872
IPR020901	Proteinase inhibitor I2, Kunitz, conserved site	PROSITE	PS00280	BPTI_KUNITZ_1	coord: 55..73

Main menu

Kunitz-type serine protease inhibitor IX

Zeng et. al., 2018

▻ Overview

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

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