Neuronal acetylcholine receptor subunit alpha-6
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30021152 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 4
Homology
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Human
Match: CHRNA6 (cholinergic receptor nicotinic alpha 6 subunit [Source:HGNC Symbol;Acc:HGNC:15963]) HSP 1 Score: 142.51 bits (358), Expect = 4.755e-36 Identity = 87/309 (28.16%), Postives = 166/309 (53.72%), Query Frame = 1
Query: 265 EEGLIKRI-ENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVD-NSYLPNSNVSEWQIEAIDFTPKKYRSDLNVS---YQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRY 1173
EE L ++ + N IRP ++ S PV V+ + Q+ + + + + W +W D +L+W+ Y + ++ + A +W PDI + N + DF +++ + Y G++TW A+ +CP+D++FFPFD+Q C L W + +I + + GS VD N + N SEW+I ID + K+ N Y I S +++R P+++ + ++IP +S L L+F L D G+++++ +S++LS+T+++++++ P + +P++G YLL + ++L+ V+ V I Y
Sbjct: 34 EERLFHKLFSHYNQFIRP---VENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLRHIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYN---NAVGDFQVEGKTKALLKYNGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLII--GSKVDMNDFWEN---SEWEI--IDASGYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVVPLVGEYLLFTMIFVTLSIVVTVFVLNIHY 329
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Human
Match: CHRNA3 (cholinergic receptor nicotinic alpha 3 subunit [Source:HGNC Symbol;Acc:HGNC:1957]) HSP 1 Score: 137.502 bits (345), Expect = 2.718e-34 Identity = 86/310 (27.74%), Postives = 167/310 (53.87%), Query Frame = 1
Query: 265 EEGLIKRI-ENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVS-----YQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRY 1173
E L +R+ E+ N IRP + S PV ++ ++ Q++ + + + + W +W D +L+WN + YG + + A+ +W PDI + N + DF +++ + YTG VTW+ A+ +C +DV++FPFDYQ C + W + +I + V GS+++ S EW I Y+ D+ + Y I S++++R PL++ + ++IP ++S L L+F L D G+++++ +S++LS+T+++++++ P + +P+IG YLL + ++L+ V+ V + Y
Sbjct: 35 EHRLFERLFEDYNEIIRPVA---NVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYN---NAVGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDL--VLIGSSMNLKDYWESG--EWAI----IKAPGYKHDIKYNCCEEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHY 330
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Human
Match: CHRNA3 (cholinergic receptor nicotinic alpha 3 subunit [Source:HGNC Symbol;Acc:HGNC:1957]) HSP 1 Score: 137.117 bits (344), Expect = 4.103e-34 Identity = 86/310 (27.74%), Postives = 167/310 (53.87%), Query Frame = 1
Query: 265 EEGLIKRI-ENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVS-----YQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRY 1173
E L +R+ E+ N IRP + S PV ++ ++ Q++ + + + + W +W D +L+WN + YG + + A+ +W PDI + N + DF +++ + YTG VTW+ A+ +C +DV++FPFDYQ C + W + +I + V GS+++ S EW I Y+ D+ + Y I S++++R PL++ + ++IP ++S L L+F L D G+++++ +S++LS+T+++++++ P + +P+IG YLL + ++L+ V+ V + Y
Sbjct: 35 EHRLFERLFEDYNEIIRPVA---NVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYN---NAVGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDL--VLIGSSMNLKDYWESG--EWAI----IKAPGYKHDIKYNCCEEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHY 330
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Human
Match: CHRNA3 (cholinergic receptor nicotinic alpha 3 subunit [Source:HGNC Symbol;Acc:HGNC:1957]) HSP 1 Score: 137.117 bits (344), Expect = 4.103e-34 Identity = 86/310 (27.74%), Postives = 167/310 (53.87%), Query Frame = 1
Query: 265 EEGLIKRI-ENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVS-----YQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRY 1173
E L +R+ E+ N IRP + S PV ++ ++ Q++ + + + + W +W D +L+WN + YG + + A+ +W PDI + N + DF +++ + YTG VTW+ A+ +C +DV++FPFDYQ C + W + +I + V GS+++ S EW I Y+ D+ + Y I S++++R PL++ + ++IP ++S L L+F L D G+++++ +S++LS+T+++++++ P + +P+IG YLL + ++L+ V+ V + Y
Sbjct: 35 EHRLFERLFEDYNEIIRPVA---NVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYN---NAVGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDL--VLIGSSMNLKDYWESG--EWAI----IKAPGYKHDIKYNCCEEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHY 330
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Human
Match: CHRNA6 (cholinergic receptor nicotinic alpha 6 subunit [Source:HGNC Symbol;Acc:HGNC:15963]) HSP 1 Score: 132.88 bits (333), Expect = 8.478e-33 Identity = 87/309 (28.16%), Postives = 162/309 (52.43%), Query Frame = 1
Query: 265 EEGLIKRI-ENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVD-NSYLPNSNVSEWQIEAIDFTPKKYRSDLNVS---YQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRY 1173
EE L ++ + N IRP ++ S PV V+ + Q+ V+W D +L+W+ Y + ++ + A +W PDI + N + DF +++ + Y G++TW A+ +CP+D++FFPFD+Q C L W + +I + + GS VD N + N SEW+I ID + K+ N Y I S +++R P+++ + ++IP +S L L+F L D G+++++ +S++LS+T+++++++ P + +P++G YLL + ++L+ V+ V I Y
Sbjct: 34 EERLFHKLFSHYNQFIRP---VENVSDPVTVHFEVAITQLA---------------NVIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYN---NAVGDFQVEGKTKALLKYNGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLII--GSKVDMNDFWEN---SEWEI--IDASGYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVVPLVGEYLLFTMIFVTLSIVVTVFVLNIHY 314
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Celegans
Match: lgc-4 (Ligand-gated ion channel 4 [Source:UniProtKB/Swiss-Prot;Acc:P54245]) HSP 1 Score: 134.42 bits (337), Expect = 3.940e-33 Identity = 85/311 (27.33%), Postives = 163/311 (52.41%), Query Frame = 1
Query: 259 GFEEGLIKRIENINLH---IRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVD----NSYLPNSNVSEWQIEAIDFTPKK----YRSDLNVSYQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVI 1155
G EE L + + + ++ +RP + H S+P V + + QI+ + + L+ W + W D RL WN +++ + +I I +W PDI ++N ++ ++++ + + V G VTWL A+ +CP+ V ++PFD Q C L W I + G D +SY+ NS + + +D T + + SD N + I + IH+ R+PL++V ++P ++S +A L F + +TG+++++ ++ +LSM +Y+ ++ + P + +P+IG+Y + L ++ LAT + VI
Sbjct: 109 GTEEALYRSLLDHTVYEKDVRPCI---HHSQPTNVTFGFLLNQIVEMDERNQALTTRSWLNINWMDPRLSWNESLWSEIKAIYIPHARIWKPDIILVN--NAIREYYASLVSTDVMVTSDGNVTWLFSALFRSSCPIRVRYYPFDDQQCDLKFASWSHD-----ITEINLGLNTDKGDLSSYMNNS-----EFDLVDMTAVREVVTFPSDTNSDWPIIVIRIHMHRRPLFYVFNHIVPCVLISSMAVLGFLMPPETGEKINMIITTLLSMGVYLQSITESIPPTSEGVPLIGMYYVSSLLMVCLATCVNVI 404
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Celegans
Match: acr-21 (pep chromosome:WBcel235:III:6583461:6586549:1 gene:WBGene00000060.1 transcript:F27B3.2d.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:acr-21) HSP 1 Score: 132.494 bits (332), Expect = 1.143e-32 Identity = 82/314 (26.11%), Postives = 161/314 (51.27%), Query Frame = 1
Query: 298 NLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQI-IIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKY-RSDLNVSYQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRYLKSLPKTKSKSHQYRCPDF 1230
N +RP V H +P+ V +++ QI+ + + L+ + W + W D +L W+ +Y N++ I I + +W PDI + N ++ ++ + + VDY G + W A+ +CPLDV +PFD QTC L W +I ++ ++G + Y+ N +EW + I + S Y +I V + ++R+ +++V +++P ++S +A + F + D+G+++++ ++ +LS T+++++V+ P + LP+IGIY + L++L T + V I + + H Y P F
Sbjct: 12 NNEVRPSV---HSKEPINVTFVFSLTQIIDVDERNQILTTNSWIRLHWVDYKLVWDPRLYQNVTRIHIPSDKIWKPDIILYNNADAQY--MKSVMSTDVIVDYLGNIHWPLSAIFTSSCPLDVKHYPFDRQTCILKYASWAYDGTKIDLLLKSEQGDLTN--YITN---TEWSLIGIRAEKNQVIYSCCPEPYPFIDVHVTIERRAMFYVFNLILPCVLISLIALMGFYMPTDSGEKVTLGITSLLSTTVFLMMVAEGMPPTAEALPLIGIYFGVTIMLVALGTAMTVFTVNIHH--------TGVHGYPVPPF 307
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Celegans
Match: acr-21 (pep chromosome:WBcel235:III:6583461:6586549:1 gene:WBGene00000060.1 transcript:F27B3.2c.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:acr-21) HSP 1 Score: 132.109 bits (331), Expect = 1.736e-32 Identity = 82/314 (26.11%), Postives = 161/314 (51.27%), Query Frame = 1
Query: 298 NLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQI-IIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKY-RSDLNVSYQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRYLKSLPKTKSKSHQYRCPDF 1230
N +RP V H +P+ V +++ QI+ + + L+ + W + W D +L W+ +Y N++ I I + +W PDI + N ++ ++ + + VDY G + W A+ +CPLDV +PFD QTC L W +I ++ ++G + Y+ N +EW + I + S Y +I V + ++R+ +++V +++P ++S +A + F + D+G+++++ ++ +LS T+++++V+ P + LP+IGIY + L++L T + V I + + H Y P F
Sbjct: 12 NNEVRPSV---HSKEPINVTFVFSLTQIIDVDERNQILTTNSWIRLHWVDYKLVWDPRLYQNVTRIHIPSDKIWKPDIILYNNADAQY--MKSVMSTDVIVDYLGNIHWPLSAIFTSSCPLDVKHYPFDRQTCILKYASWAYDGTKIDLLLKSEQGDLTN--YITN---TEWSLIGIRAEKNQVIYSCCPEPYPFIDVHVTIERRAMFYVFNLILPCVLISLIALMGFYMPTDSGEKVTLGITSLLSTTVFLMMVAEGMPPTAEALPLIGIYFGVTIMLVALGTAMTVFTVNIHH--------TGVHGYPVPPF 307
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Celegans
Match: acr-21 (pep chromosome:WBcel235:III:6581927:6586549:1 gene:WBGene00000060.1 transcript:F27B3.2b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:acr-21) HSP 1 Score: 132.494 bits (332), Expect = 1.740e-32 Identity = 82/314 (26.11%), Postives = 161/314 (51.27%), Query Frame = 1
Query: 298 NLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQI-IIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKY-RSDLNVSYQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRYLKSLPKTKSKSHQYRCPDF 1230
N +RP V H +P+ V +++ QI+ + + L+ + W + W D +L W+ +Y N++ I I + +W PDI + N ++ ++ + + VDY G + W A+ +CPLDV +PFD QTC L W +I ++ ++G + Y+ N +EW + I + S Y +I V + ++R+ +++V +++P ++S +A + F + D+G+++++ ++ +LS T+++++V+ P + LP+IGIY + L++L T + V I + + H Y P F
Sbjct: 43 NNEVRPSV---HSKEPINVTFVFSLTQIIDVDERNQILTTNSWIRLHWVDYKLVWDPRLYQNVTRIHIPSDKIWKPDIILYNNADAQY--MKSVMSTDVIVDYLGNIHWPLSAIFTSSCPLDVKHYPFDRQTCILKYASWAYDGTKIDLLLKSEQGDLTN--YITN---TEWSLIGIRAEKNQVIYSCCPEPYPFIDVHVTIERRAMFYVFNLILPCVLISLIALMGFYMPTDSGEKVTLGITSLLSTTVFLMMVAEGMPPTAEALPLIGIYFGVTIMLVALGTAMTVFTVNIHH--------TGVHGYPVPPF 338
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Celegans
Match: acr-21 (pep chromosome:WBcel235:III:6581927:6586549:1 gene:WBGene00000060.1 transcript:F27B3.2a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:acr-21) HSP 1 Score: 132.494 bits (332), Expect = 1.962e-32 Identity = 82/314 (26.11%), Postives = 161/314 (51.27%), Query Frame = 1
Query: 298 NLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQI-IIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKY-RSDLNVSYQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRYLKSLPKTKSKSHQYRCPDF 1230
N +RP V H +P+ V +++ QI+ + + L+ + W + W D +L W+ +Y N++ I I + +W PDI + N ++ ++ + + VDY G + W A+ +CPLDV +PFD QTC L W +I ++ ++G + Y+ N +EW + I + S Y +I V + ++R+ +++V +++P ++S +A + F + D+G+++++ ++ +LS T+++++V+ P + LP+IGIY + L++L T + V I + + H Y P F
Sbjct: 43 NNEVRPSV---HSKEPINVTFVFSLTQIIDVDERNQILTTNSWIRLHWVDYKLVWDPRLYQNVTRIHIPSDKIWKPDIILYNNADAQY--MKSVMSTDVIVDYLGNIHWPLSAIFTSSCPLDVKHYPFDRQTCILKYASWAYDGTKIDLLLKSEQGDLTN--YITN---TEWSLIGIRAEKNQVIYSCCPEPYPFIDVHVTIERRAMFYVFNLILPCVLISLIALMGFYMPTDSGEKVTLGITSLLSTTVFLMMVAEGMPPTAEALPLIGIYFGVTIMLVALGTAMTVFTVNIHH--------TGVHGYPVPPF 338
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Fly
Match: nAChRalpha2 (gene:FBgn0000039 transcript:FBtr0084639) HSP 1 Score: 132.494 bits (332), Expect = 1.397e-32 Identity = 85/309 (27.51%), Postives = 161/309 (52.10%), Query Frame = 1
Query: 286 IENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDN---------SYLPNSNVSEWQIEAIDFT-PKKYRSDLNVSYQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRYLK 1179
+ N N IRP + + V V + + Q++ + ++ L+ + W W+D + +W+ + YG ++ + + ++ +WLPDI + N + + ++ ++ + YTG V W A+ +C +DV +FPFD QTC++ W QI + + + + DN Y P+ EW I + +KY Y I +I L+R+ L++ V ++IP +S L+ L+F L D+G+++++ +S++LS TM+ +++S P + LP++G YLL + L+ L+ V+ +I I Y K
Sbjct: 53 LSNYNRLIRP---VSNNTDTVLVKLGLRLSQLIDLNLKDQILTTNVWLEHEWQDHKFKWDPSEYGGVTELYVPSEHIWLPDIVLYN---NADGEYVVTTMTKAILHYTGKVVWTPPAIFKSSCEIDVRYFPFDQQTCFMKFGSWTYDGDQIDLKHISQKNDKDNKVEIGIDLREYYPS---VEWDILGVPAERHEKYYPCCAEPYPDIFFNITLRRKTLFYTVNLIIPCVGISYLSVLVFYLPADSGEKIALCISILLSQTMFFLLISEIIPSTSLALPLLGKYLLFTMLLVGLSVVITIIILNIHYRK 352
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Fly
Match: nAChRalpha2 (gene:FBgn0000039 transcript:FBtr0084640) HSP 1 Score: 132.494 bits (332), Expect = 1.397e-32 Identity = 85/309 (27.51%), Postives = 161/309 (52.10%), Query Frame = 1
Query: 286 IENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDN---------SYLPNSNVSEWQIEAIDFT-PKKYRSDLNVSYQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRYLK 1179
+ N N IRP + + V V + + Q++ + ++ L+ + W W+D + +W+ + YG ++ + + ++ +WLPDI + N + + ++ ++ + YTG V W A+ +C +DV +FPFD QTC++ W QI + + + + DN Y P+ EW I + +KY Y I +I L+R+ L++ V ++IP +S L+ L+F L D+G+++++ +S++LS TM+ +++S P + LP++G YLL + L+ L+ V+ +I I Y K
Sbjct: 53 LSNYNRLIRP---VSNNTDTVLVKLGLRLSQLIDLNLKDQILTTNVWLEHEWQDHKFKWDPSEYGGVTELYVPSEHIWLPDIVLYN---NADGEYVVTTMTKAILHYTGKVVWTPPAIFKSSCEIDVRYFPFDQQTCFMKFGSWTYDGDQIDLKHISQKNDKDNKVEIGIDLREYYPS---VEWDILGVPAERHEKYYPCCAEPYPDIFFNITLRRKTLFYTVNLIIPCVGISYLSVLVFYLPADSGEKIALCISILLSQTMFFLLISEIIPSTSLALPLLGKYLLFTMLLVGLSVVITIIILNIHYRK 352
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Fly
Match: nAChRalpha6 (gene:FBgn0032151 transcript:FBtr0331284) HSP 1 Score: 119.398 bits (298), Expect = 1.810e-28 Identity = 73/294 (24.83%), Postives = 146/294 (49.66%), Query Frame = 1
Query: 241 KETTQIGFEEGLIKRIENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVS----YQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYL 1107
KE+ Q E+ L+ + + + PV + S+P++V + QI+ + + L+ + W + W D L+WN YG + + I +W PD+ + N S + F + I V + G ++ + TC +D+++FPFD Q C + W Q+ + + ++ N EW + A+ P K + + Y I +I ++R+ LY+ +++P ++S +A L FTL D+G++L++ ++++LS+T+++ +V+ + P + +P+IG Y
Sbjct: 22 KESCQGPHEKRLLNHLLSTYNTLERPVANE--SEPLEVKFGLTLQQIIDVDEKNQILTTNAWLNLEWNDYNLRWNETEYGGVKDLRITPNKLWKPDVLMYN---SADEGFDGTYHTNIVVKHNGSCLYVPPGIFKSTCKIDITWFPFDDQHCEMKFGSWTYDGNQLDLVLNSEDGGDLSDFITN---GEWYLLAM---PGKKNTIVYACCPEPYVDITFTIQIRRRTLYYFFNLIVPCVLISSMALLGFTLPPDSGEKLTLGVTILLSLTVFLNLVAESMPTTSDAVPLIGTYF 304
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Fly
Match: nAChRalpha6 (gene:FBgn0032151 transcript:FBtr0079912) HSP 1 Score: 119.013 bits (297), Expect = 3.986e-28 Identity = 73/295 (24.75%), Postives = 148/295 (50.17%), Query Frame = 1
Query: 241 KETTQIGFEEGLIKRIENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVS----YQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLL 1110
KE+ Q E+ L+ + + + PV + S+P++V + QI+ + + L+ + W + W D L+WN YG + + I +W PD+ + N S + F + I V + G ++ + TC +D+++FPFD Q C + W Q+ + + ++ N EW + A+ P K + + Y I +I ++R+ LY+ +++P ++S +A L FTL D+G++L++ ++++LS+T+++ +V+ + P + +P+IG+ +L
Sbjct: 22 KESCQGPHEKRLLNHLLSTYNTLERPVANE--SEPLEVKFGLTLQQIIDVDEKNQILTTNAWLNLEWNDYNLRWNETEYGGVKDLRITPNKLWKPDVLMYN---SADEGFDGTYHTNIVVKHNGSCLYVPPGIFKSTCKIDITWFPFDDQHCEMKFGSWTYDGNQLDLVLNSEDGGDLSDFITN---GEWYLLAM---PGKKNTIVYACCPEPYVDITFTIQIRRRTLYYFFNLIVPCVLISSMALLGFTLPPDSGEKLTLGVTILLSLTVFLNLVAESMPTTSDAVPLIGVTIL 305
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Fly
Match: nAChRalpha6 (gene:FBgn0032151 transcript:FBtr0079915) HSP 1 Score: 117.857 bits (294), Expect = 5.973e-28 Identity = 72/294 (24.49%), Postives = 145/294 (49.32%), Query Frame = 1
Query: 241 KETTQIGFEEGLIKRIENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVS----YQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYL 1107
KE+ Q E+ L+ + + + PV + S+P++V + QI+ + + L+ + W + W D L+WN YG + + I +W PD+ + N S + F + I V + G ++ + TC +D+++FPFD Q C + W Q+ + + ++ N EW + A+ P K + + Y I +I ++R+ LY+ +++P ++S +A L FTL D+G++L++ ++++LS+T+++ +V+ P+ +P++G Y
Sbjct: 22 KESCQGPHEKRLLNHLLSTYNTLERPVANE--SEPLEVKFGLTLQQIIDVDEKNQILTTNAWLNLEWNDYNLRWNETEYGGVKDLRITPNKLWKPDVLMYN---SADEGFDGTYHTNIVVKHNGSCLYVPPGIFKSTCKIDITWFPFDDQHCEMKFGSWTYDGNQLDLVLNSEDGGDLSDFITN---GEWYLLAM---PGKKNTIVYACCPEPYVDITFTIQIRRRTLYYFFNLIVPCVLISSMALLGFTLPPDSGEKLTLGVTILLSLTVFLNLVAETLPQVSDAIPLLGTYF 304
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Zebrafish
Match: chrne (cholinergic receptor, nicotinic, epsilon [Source:ZFIN;Acc:ZDB-GENE-040808-32]) HSP 1 Score: 145.206 bits (365), Expect = 4.994e-37 Identity = 94/334 (28.14%), Postives = 180/334 (53.89%), Query Frame = 1
Query: 259 GFEEG--LIKRIENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVI--NPWQSSEKQIIIYPVQRGSAVD------NSYLPNSNVSEWQIE---AIDFTPKKYRSDLNVSYQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL--DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSL--ATVLAVINNKIRYLKSLPKTKSKSH 1209
G EE + + +N + +IRP H + VKV + + +++ ++ EETL+ + W + W D RL WN + Y ++ I + +WLPDI + N K FD + A IS D G + WL A+ TC +++++FPFD+Q C LV + ++E I++ + G ++ ++ N EW I+ A T ++Y D ++ YQ + +I ++R+PL++V+ +++P S++S L L + L G +L+V++S++L+ T++++++S P + +P+IG YL+ + + +L + V+N +R + ++S H
Sbjct: 26 GNEESQLIADKFKNYSKNIRPA---RHADEKVKVQVKLTLTNLISLNEKEETLTTNVWIEIQWHDYRLAWNTSEYHDIEQIRVPYYTVWLPDIVLENNIDGK-FDVAYYANVLISSD--GSMYWLPPAIYRSTCAIEITYFPFDWQNCTLVFRSQTYSANEIDIVLAEDENGKPIEWVDIDPEAFTEN---GEWAIKHRPARKLTNQRYSPD-DLEYQEVYYNIIIQRKPLFYVINIILPCSLISSLVVLAYFLPAKAGGQKLTVSISVLLAQTVFLILISQKIPETSLSVPLIGKYLIFVMSMTTLIVTNCIIVLNYSLRSPSTHNMSQSIKH 349
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Zebrafish
Match: chrne (cholinergic receptor, nicotinic, epsilon [Source:ZFIN;Acc:ZDB-GENE-040808-32]) HSP 1 Score: 145.206 bits (365), Expect = 4.994e-37 Identity = 94/334 (28.14%), Postives = 180/334 (53.89%), Query Frame = 1
Query: 259 GFEEG--LIKRIENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVI--NPWQSSEKQIIIYPVQRGSAVD------NSYLPNSNVSEWQIE---AIDFTPKKYRSDLNVSYQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL--DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSL--ATVLAVINNKIRYLKSLPKTKSKSH 1209
G EE + + +N + +IRP H + VKV + + +++ ++ EETL+ + W + W D RL WN + Y ++ I + +WLPDI + N K FD + A IS D G + WL A+ TC +++++FPFD+Q C LV + ++E I++ + G ++ ++ N EW I+ A T ++Y D ++ YQ + +I ++R+PL++V+ +++P S++S L L + L G +L+V++S++L+ T++++++S P + +P+IG YL+ + + +L + V+N +R + ++S H
Sbjct: 26 GNEESQLIADKFKNYSKNIRPA---RHADEKVKVQVKLTLTNLISLNEKEETLTTNVWIEIQWHDYRLAWNTSEYHDIEQIRVPYYTVWLPDIVLENNIDGK-FDVAYYANVLISSD--GSMYWLPPAIYRSTCAIEITYFPFDWQNCTLVFRSQTYSANEIDIVLAEDENGKPIEWVDIDPEAFTEN---GEWAIKHRPARKLTNQRYSPD-DLEYQEVYYNIIIQRKPLFYVINIILPCSLISSLVVLAYFLPAKAGGQKLTVSISVLLAQTVFLILISQKIPETSLSVPLIGKYLIFVMSMTTLIVTNCIIVLNYSLRSPSTHNMSQSIKH 349
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Zebrafish
Match: chrnb3b (cholinergic receptor, nicotinic, beta 3b (neuronal) [Source:ZFIN;Acc:ZDB-GENE-030102-4]) HSP 1 Score: 135.191 bits (339), Expect = 6.635e-34 Identity = 95/335 (28.36%), Postives = 165/335 (49.25%), Query Frame = 1
Query: 331 HCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSS----EKQIIIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVSYQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLA--VINNKIR---------------YLKSLPK---TKSKSHQYRCPDFTVDSPIMELR 1260
H + VKV + Q++ + + ++ + W W D +L+WN YG ++ I + ++ +WLPDI V+ F+ S + ++ V Y G++TW A C +DV+FFPFD Q C + W E ++ + V R DN EW+I + K R D + SY YI S LKR PL++ + ++IP LS L L+F L D G+++S++ S+++S+T++++++ P S + +P+IG YLL + ++L+ ++ VIN R +L+ LP + + +Y P SP ++ R
Sbjct: 51 HANHTVKVRFGLKISQLVDVDEKNQLMTTNVWLYEEWLDYKLRWNPENYGGITFIRVPSESIWLPDI-VLYENADGRFEGSIMTKA--IVRYNGLITWTPPASYKSACTMDVTFFPFDRQNCSMKFGSWTYDGNMVELVLVNHQVDRSDFFDN--------GEWEILSAT-GHKGSRRDGHYSYPYITYSFILKRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEGEKVSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIVTVFVINVHHRSSATYHPMSPWVRTLFLQRLPDLLCMRGNTDRYHYPQMEPQSPDLKPR 373
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Zebrafish
Match: chrna6 (cholinergic receptor, nicotinic, alpha 6 [Source:ZFIN;Acc:ZDB-GENE-090312-91]) HSP 1 Score: 133.265 bits (334), Expect = 5.669e-33 Identity = 82/303 (27.06%), Postives = 160/303 (52.81%), Query Frame = 1
Query: 298 NLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVS---YQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRYLKSLPKT 1194
N IRP ++ S PV V ++ Q++ + + + + W +W D +L+W+ A + + I + + +W PDI + N + DF +++ + + G +TW+ A+ +CP+D+++FPFDYQ C + W + +I + V GS V+ S EW+I ID K+ N Y I S +++R PL++ + ++IP ++S L L+F L D G+++++ +S++LS+T+++++++ P + +P+IG YLL + ++L+ V+ V + Y + T
Sbjct: 25 NQFIRP---VENVSDPVTVEFEVSISQLVKVDEVNQIMETNLWLRHIWNDYKLKWSPAEFDGIEFIRVPSNKIWRPDIVLYN---NAVGDFLVEDKTKALLKFDGTITWVPPAIFKSSCPMDITYFPFDYQNCSMKFGSWTYDKAKIDL--VLIGSKVNLKDFWESG--EWEI--IDAPGYKHDIKYNCCEEIYPDITYSFYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPMTHT 315
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Zebrafish
Match: chrna6 (cholinergic receptor, nicotinic, alpha 6 [Source:ZFIN;Acc:ZDB-GENE-090312-91]) HSP 1 Score: 133.265 bits (334), Expect = 6.521e-33 Identity = 82/303 (27.06%), Postives = 160/303 (52.81%), Query Frame = 1
Query: 298 NLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVS---YQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRYLKSLPKT 1194
N IRP ++ S PV V ++ Q++ + + + + W +W D +L+W+ A + + I + + +W PDI + N + DF +++ + + G +TW+ A+ +CP+D+++FPFDYQ C + W + +I + V GS V+ S EW+I ID K+ N Y I S +++R PL++ + ++IP ++S L L+F L D G+++++ +S++LS+T+++++++ P + +P+IG YLL + ++L+ V+ V + Y + T
Sbjct: 39 NQFIRP---VENVSDPVTVEFEVSISQLVKVDEVNQIMETNLWLRHIWNDYKLKWSPAEFDGIEFIRVPSNKIWRPDIVLYN---NAVGDFLVEDKTKALLKFDGTITWVPPAIFKSSCPMDITYFPFDYQNCSMKFGSWTYDKAKIDL--VLIGSKVNLKDFWESG--EWEI--IDAPGYKHDIKYNCCEEIYPDITYSFYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPMTHT 329
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Xenopus
Match: ncaph (non-SMC condensin I complex subunit H [Source:Xenbase;Acc:XB-GENE-5738397]) HSP 1 Score: 150.214 bits (378), Expect = 4.076e-39 Identity = 92/313 (29.39%), Postives = 167/313 (53.35%), Query Frame = 1
Query: 253 QIGFEEGLIKRI-ENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVD-NSYLPNSNVSEWQIEAIDFTPKKYRSDLNVS---YQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRY 1173
Q EE L +++ N HIRP ++ S PV V+ + Q++ + + L + W +W D +LQWN Y + + I A +W PDI + N + DF +S+ V Y G++TW A+ +CP+D++FFPFD+Q C + W + +I + + GS VD + N SEW+I +D + K+ N Y I S +++R P+++ + +++P LS L L+F L D G+++++ +S++LS+T+++++++ P + +P++G YLL + ++L+ V+ V I Y
Sbjct: 18 QCETEEKLFQKLLARYNQHIRPV---ENVSDPVMVHFEVAITQLVNVDEVNQILETNLWLRHIWNDYKLQWNPKEYDGIEFMRIPADKIWKPDIVLYN---NAVGDFQVEGKSKALVKYNGLITWSPPAIFKSSCPMDITFFPFDHQNCSMKFGSWSYDKAKIDLAII--GSKVDMKDFWEN---SEWEI--VDASGFKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIMPCLFLSFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVVTVFVLNIHY 317
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Xenopus
Match: ncaph (non-SMC condensin I complex subunit H [Source:Xenbase;Acc:XB-GENE-5738397]) HSP 1 Score: 150.214 bits (378), Expect = 4.780e-39 Identity = 92/313 (29.39%), Postives = 167/313 (53.35%), Query Frame = 1
Query: 253 QIGFEEGLIKRI-ENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVD-NSYLPNSNVSEWQIEAIDFTPKKYRSDLNVS---YQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRY 1173
Q EE L +++ N HIRP ++ S PV V+ + Q++ + + L + W +W D +LQWN Y + + I A +W PDI + N + DF +S+ V Y G++TW A+ +CP+D++FFPFD+Q C + W + +I + + GS VD + N SEW+I +D + K+ N Y I S +++R P+++ + +++P LS L L+F L D G+++++ +S++LS+T+++++++ P + +P++G YLL + ++L+ V+ V I Y
Sbjct: 12 QCETEEKLFQKLLARYNQHIRPV---ENVSDPVMVHFEVAITQLVNVDEVNQILETNLWLRHIWNDYKLQWNPKEYDGIEFMRIPADKIWKPDIVLYN---NAVGDFQVEGKSKALVKYNGLITWSPPAIFKSSCPMDITFFPFDHQNCSMKFGSWSYDKAKIDLAII--GSKVDMKDFWEN---SEWEI--VDASGFKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIMPCLFLSFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVVTVFVLNIHY 311
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Xenopus
Match: ncaph (non-SMC condensin I complex subunit H [Source:Xenbase;Acc:XB-GENE-5738397]) HSP 1 Score: 150.214 bits (378), Expect = 4.846e-39 Identity = 92/313 (29.39%), Postives = 167/313 (53.35%), Query Frame = 1
Query: 253 QIGFEEGLIKRI-ENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVD-NSYLPNSNVSEWQIEAIDFTPKKYRSDLNVS---YQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRY 1173
Q EE L +++ N HIRP ++ S PV V+ + Q++ + + L + W +W D +LQWN Y + + I A +W PDI + N + DF +S+ V Y G++TW A+ +CP+D++FFPFD+Q C + W + +I + + GS VD + N SEW+I +D + K+ N Y I S +++R P+++ + +++P LS L L+F L D G+++++ +S++LS+T+++++++ P + +P++G YLL + ++L+ V+ V I Y
Sbjct: 23 QCETEEKLFQKLLARYNQHIRPV---ENVSDPVMVHFEVAITQLVNVDEVNQILETNLWLRHIWNDYKLQWNPKEYDGIEFMRIPADKIWKPDIVLYN---NAVGDFQVEGKSKALVKYNGLITWSPPAIFKSSCPMDITFFPFDHQNCSMKFGSWSYDKAKIDLAII--GSKVDMKDFWEN---SEWEI--VDASGFKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIMPCLFLSFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVVTVFVLNIHY 322
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Xenopus
Match: ncaph (non-SMC condensin I complex subunit H [Source:Xenbase;Acc:XB-GENE-5738397]) HSP 1 Score: 149.828 bits (377), Expect = 5.256e-39 Identity = 92/313 (29.39%), Postives = 167/313 (53.35%), Query Frame = 1
Query: 253 QIGFEEGLIKRI-ENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVD-NSYLPNSNVSEWQIEAIDFTPKKYRSDLNVS---YQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRY 1173
Q EE L +++ N HIRP ++ S PV V+ + Q++ + + L + W +W D +LQWN Y + + I A +W PDI + N + DF +S+ V Y G++TW A+ +CP+D++FFPFD+Q C + W + +I + + GS VD + N SEW+I +D + K+ N Y I S +++R P+++ + +++P LS L L+F L D G+++++ +S++LS+T+++++++ P + +P++G YLL + ++L+ V+ V I Y
Sbjct: 17 QCETEEKLFQKLLARYNQHIRPV---ENVSDPVMVHFEVAITQLVNVDEVNQILETNLWLRHIWNDYKLQWNPKEYDGIEFMRIPADKIWKPDIVLYN---NAVGDFQVEGKSKALVKYNGLITWSPPAIFKSSCPMDITFFPFDHQNCSMKFGSWSYDKAKIDLAII--GSKVDMKDFWEN---SEWEI--VDASGFKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIMPCLFLSFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVVTVFVLNIHY 316
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Xenopus
Match: ncaph (non-SMC condensin I complex subunit H [Source:Xenbase;Acc:XB-GENE-5738397]) HSP 1 Score: 149.828 bits (377), Expect = 6.691e-39 Identity = 92/313 (29.39%), Postives = 167/313 (53.35%), Query Frame = 1
Query: 253 QIGFEEGLIKRI-ENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVD-NSYLPNSNVSEWQIEAIDFTPKKYRSDLNVS---YQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRY 1173
Q EE L +++ N HIRP ++ S PV V+ + Q++ + + L + W +W D +LQWN Y + + I A +W PDI + N + DF +S+ V Y G++TW A+ +CP+D++FFPFD+Q C + W + +I + + GS VD + N SEW+I +D + K+ N Y I S +++R P+++ + +++P LS L L+F L D G+++++ +S++LS+T+++++++ P + +P++G YLL + ++L+ V+ V I Y
Sbjct: 30 QCETEEKLFQKLLARYNQHIRPV---ENVSDPVMVHFEVAITQLVNVDEVNQILETNLWLRHIWNDYKLQWNPKEYDGIEFMRIPADKIWKPDIVLYN---NAVGDFQVEGKSKALVKYNGLITWSPPAIFKSSCPMDITFFPFDHQNCSMKFGSWSYDKAKIDLAII--GSKVDMKDFWEN---SEWEI--VDASGFKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIMPCLFLSFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVVTVFVLNIHY 329
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Mouse
Match: Chrna6 (cholinergic receptor, nicotinic, alpha polypeptide 6 [Source:MGI Symbol;Acc:MGI:106213]) HSP 1 Score: 150.984 bits (380), Expect = 3.052e-39 Identity = 94/327 (28.75%), Postives = 173/327 (52.91%), Query Frame = 1
Query: 241 KETTQIGFEEGLIKRI-ENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVD-NSYLPNSNVSEWQIEAIDFTPKKYRSDLNVS---YQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRYLKSLPKTKSK 1203
K +T EE L R+ + N IRP ++ S PV V+ + Q+ + + + + W +WKD RL+W+ Y + ++ + A ++W PDI + N + DF +++ + Y GV+TW A+ +CP+D++FFPFD+Q C L W + +I + + GS VD N + N SEW+I +D + K+ N Y I S +++R P+++ + ++IP +S L L+F L D G+++++ +S++LS+T+++++++ P + +P++G YLL + ++L+ V+ V I Y T K
Sbjct: 26 KGSTGCESEEQLFHRLFAHYNRFIRPV---ENVSDPVTVHFELAITQLANVDEVNQIMETNLWLRHIWKDYRLRWDPTEYDGIETLRVPADNIWKPDIVLYN---NAVGDFQVEGKTKALLKYDGVITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLII--GSKVDMNDFWEN---SEWEI--VDASGYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVVTVFVLNIHYRTPATHTMPK 339
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Mouse
Match: Chrna3 (cholinergic receptor, nicotinic, alpha polypeptide 3 [Source:MGI Symbol;Acc:MGI:87887]) HSP 1 Score: 134.035 bits (336), Expect = 2.209e-33 Identity = 83/299 (27.76%), Postives = 161/299 (53.85%), Query Frame = 1
Query: 289 ENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVS---YQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRY 1173
E+ N IRP + S PV + ++ Q++ + + + + W +W D +L+W + Y + + + A+ +W PDI + N + + DF +++ + YTG VTW+ A+ +C +DV++FPFDYQ C + W + +I + V GS+++ S EW I I K+ N YQ I S++++R PL++ + ++IP ++S L L+F L D G+++++ +S++LS+T+++++++ P + +P+IG YLL + ++L+ V+ V + Y
Sbjct: 38 EDYNEIIRPVA---NVSHPVIIQFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWKPSDYQGVEFMRVPAEKIWKPDIVLYN---NADGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDL--VLIGSSMNLKDYWESG--EWAI--IKAPGYKHEIKYNCCEEIYQDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHY 324
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Mouse
Match: Chrna3 (cholinergic receptor, nicotinic, alpha polypeptide 3 [Source:MGI Symbol;Acc:MGI:87887]) HSP 1 Score: 134.035 bits (336), Expect = 3.357e-33 Identity = 83/299 (27.76%), Postives = 161/299 (53.85%), Query Frame = 1
Query: 289 ENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVS---YQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRY 1173
E+ N IRP + S PV + ++ Q++ + + + + W +W D +L+W + Y + + + A+ +W PDI + N + + DF +++ + YTG VTW+ A+ +C +DV++FPFDYQ C + W + +I + V GS+++ S EW I I K+ N YQ I S++++R PL++ + ++IP ++S L L+F L D G+++++ +S++LS+T+++++++ P + +P+IG YLL + ++L+ V+ V + Y
Sbjct: 38 EDYNEIIRPVA---NVSHPVIIQFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWKPSDYQGVEFMRVPAEKIWKPDIVLYN---NADGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDL--VLIGSSMNLKDYWESG--EWAI--IKAPGYKHEIKYNCCEEIYQDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHY 324
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Mouse
Match: Chrna3 (cholinergic receptor, nicotinic, alpha polypeptide 3 [Source:MGI Symbol;Acc:MGI:87887]) HSP 1 Score: 133.65 bits (335), Expect = 4.227e-33 Identity = 83/299 (27.76%), Postives = 161/299 (53.85%), Query Frame = 1
Query: 289 ENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVS---YQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRY 1173
E+ N IRP + S PV + ++ Q++ + + + + W +W D +L+W + Y + + + A+ +W PDI + N + + DF +++ + YTG VTW+ A+ +C +DV++FPFDYQ C + W + +I + V GS+++ S EW I I K+ N YQ I S++++R PL++ + ++IP ++S L L+F L D G+++++ +S++LS+T+++++++ P + +P+IG YLL + ++L+ V+ V + Y
Sbjct: 43 EDYNEIIRPVA---NVSHPVIIQFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWKPSDYQGVEFMRVPAEKIWKPDIVLYN---NADGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDL--VLIGSSMNLKDYWESG--EWAI--IKAPGYKHEIKYNCCEEIYQDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHY 329
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Mouse
Match: Chrna5 (cholinergic receptor, nicotinic, alpha polypeptide 5 [Source:MGI Symbol;Acc:MGI:87889]) HSP 1 Score: 127.102 bits (318), Expect = 3.509e-31 Identity = 84/312 (26.92%), Postives = 155/312 (49.68%), Query Frame = 1
Query: 265 EEGLIKRI-ENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIII----YPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVSYQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRYLKS 1182
E+ L + + E+ +RP +H S +K+ + Q++ + + ++ + W W D++L+WN YG + I + + +W+PDI + + + F A ++ V Y G VTW A +C +DV+FFPFD Q C + W Q+ I V R DN EW+I + K R+D Y I S +KR PL++ + ++IP LS L ++F L + G+++S+ S+++S+T++++++ P S + +P+IG YL+ + ++L+ ++ V I + S
Sbjct: 18 EDSLFRDLFEDYEKWVRPV---EHLSDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLRWNPDDYGGIKIIRVPSDSLWIPDIVLFDNADGR---FEG-ASTKTVVRYNGTVTWTQPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDRTDFFDN--------GEWEIMSA-MGSKGNRTDSCCWYPCITYSFVIKRLPLFYTLFLIIPCIGLSFLTVVVFYLPSNEGEKISLCTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLVFTMIFVTLSIMVTVFAINIHHRSS 313
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. UniProt/SwissProt
Match: sp|Q9R0W9|ACHA6_MOUSE (Neuronal acetylcholine receptor subunit alpha-6 OS=Mus musculus OX=10090 GN=Chrna6 PE=2 SV=2) HSP 1 Score: 150.984 bits (380), Expect = 2.135e-38 Identity = 94/327 (28.75%), Postives = 173/327 (52.91%), Query Frame = 1
Query: 241 KETTQIGFEEGLIKRI-ENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVD-NSYLPNSNVSEWQIEAIDFTPKKYRSDLNVS---YQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRYLKSLPKTKSK 1203
K +T EE L R+ + N IRP ++ S PV V+ + Q+ + + + + W +WKD RL+W+ Y + ++ + A ++W PDI + N + DF +++ + Y GV+TW A+ +CP+D++FFPFD+Q C L W + +I + + GS VD N + N SEW+I +D + K+ N Y I S +++R P+++ + ++IP +S L L+F L D G+++++ +S++LS+T+++++++ P + +P++G YLL + ++L+ V+ V I Y T K
Sbjct: 26 KGSTGCESEEQLFHRLFAHYNRFIRPV---ENVSDPVTVHFELAITQLANVDEVNQIMETNLWLRHIWKDYRLRWDPTEYDGIETLRVPADNIWKPDIVLYN---NAVGDFQVEGKTKALLKYDGVITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLII--GSKVDMNDFWEN---SEWEI--VDASGYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVVTVFVLNIHYRTPATHTMPK 339
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. UniProt/SwissProt
Match: sp|P43143|ACHA6_RAT (Neuronal acetylcholine receptor subunit alpha-6 OS=Rattus norvegicus OX=10116 GN=Chrna6 PE=2 SV=1) HSP 1 Score: 146.362 bits (368), Expect = 1.145e-36 Identity = 92/319 (28.84%), Postives = 168/319 (52.66%), Query Frame = 1
Query: 265 EEGLIKRI-ENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVD-NSYLPNSNVSEWQIEAIDFTPKKYRSDLNVS---YQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRYLKSLPKTKSK 1203
EE L + + N IRP ++ S PV V+ + Q+ + + + + W VWKD RL W+ Y + ++ + A ++W PDI + N + DF +++ + Y GV+TW A+ +CP+D++FFPFD+Q C L W + +I + + GS VD N + N SEW+I +D + K+ N Y I S +++R P+++ + ++IP +S L L+F L D G+++++ +S++LS+T+++++++ P + +P++G YLL + ++L+ V+ V I Y T K
Sbjct: 34 EEQLFHTLFAHYNRFIRP---VENVSDPVTVHFELAITQLANVDEVNQIMETNLWLRHVWKDYRLCWDPTEYDGIETLRVPADNIWKPDIVLYN---NAVGDFQVEGKTKALLKYDGVITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLII--GSKVDMNDFWEN---SEWEI--VDASGYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVVTVFVLNIHYRTPATHTMPK 339
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. UniProt/SwissProt
Match: sp|Q5IS76|ACHA6_PANTR (Neuronal acetylcholine receptor subunit alpha-6 OS=Pan troglodytes OX=9598 GN=CHRNA6 PE=2 SV=1) HSP 1 Score: 142.895 bits (359), Expect = 1.504e-35 Identity = 88/309 (28.48%), Postives = 166/309 (53.72%), Query Frame = 1
Query: 265 EEGLIKRI-ENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVD-NSYLPNSNVSEWQIEAIDFTPKKYRSDLNVS---YQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRY 1173
EE L ++ + N IRP ++ S PV V+ + Q+ + + + + W +W D +L+W+ Y + ++ I A +W PDI + N + DF +++ + Y G++TW A+ +CP+D++FFPFD+Q C L W + +I + + GS VD N + N SEW+I ID + K+ N Y I S +++R P+++ + ++IP +S L L+F L D G+++++ +S++LS+T+++++++ P + +P++G YLL + ++L+ V+ V I Y
Sbjct: 34 EERLFHKLFSHYNQFIRP---VENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLRHIWNDYKLRWDPMEYDGIETLRIPADKIWKPDIVLYN---NAVGDFQVEGKTKALLKYNGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLII--GSKVDMNDFWEN---SEWEI--IDASGYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVVPLVGEYLLFTMIFVTLSIVVTVFVLNIHY 329
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. UniProt/SwissProt
Match: sp|Q15825|ACHA6_HUMAN (Neuronal acetylcholine receptor subunit alpha-6 OS=Homo sapiens OX=9606 GN=CHRNA6 PE=1 SV=1) HSP 1 Score: 142.51 bits (358), Expect = 2.284e-35 Identity = 87/309 (28.16%), Postives = 166/309 (53.72%), Query Frame = 1
Query: 265 EEGLIKRI-ENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVD-NSYLPNSNVSEWQIEAIDFTPKKYRSDLNVS---YQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRY 1173
EE L ++ + N IRP ++ S PV V+ + Q+ + + + + W +W D +L+W+ Y + ++ + A +W PDI + N + DF +++ + Y G++TW A+ +CP+D++FFPFD+Q C L W + +I + + GS VD N + N SEW+I ID + K+ N Y I S +++R P+++ + ++IP +S L L+F L D G+++++ +S++LS+T+++++++ P + +P++G YLL + ++L+ V+ V I Y
Sbjct: 34 EERLFHKLFSHYNQFIRP---VENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLRHIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYN---NAVGDFQVEGKTKALLKYNGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLII--GSKVDMNDFWEN---SEWEI--IDASGYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVVPLVGEYLLFTMIFVTLSIVVTVFVLNIHY 329
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. UniProt/SwissProt
Match: sp|P13908|ACHN2_CARAU (Neuronal acetylcholine receptor subunit non-alpha-2 OS=Carassius auratus OX=7957 PE=2 SV=1) HSP 1 Score: 138.658 bits (348), Expect = 3.352e-34 Identity = 100/358 (27.93%), Postives = 176/358 (49.16%), Query Frame = 1
Query: 265 EEGLIKRI-ENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQI----IIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVSYQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLA--VINNKIR---------------YLKSLPK---TKSKSHQYRCPDFTVDSPIMELR 1260
E+ L++ + + +RP H + VKV + Q++ + + ++ + W W D +L+WN YG ++SI + ++ +WLPDI V+ F+ S + ++ V Y G++TW A C +DV+FFPFD Q C + W + I V R DN EW+I + K R D ++SY YI S LKR PL++ + ++IP LS L L+F L D G+++S++ S+++S+T++++++ P S + +P+IG YLL + ++L+ ++ VIN R +L+ LP + + +Y P+ SP ++ R
Sbjct: 31 EDALLRELFQGYQRWVRP---VQHANHSVKVRFGLKISQLVDVDEKNQLMTTNVWLWQEWLDYKLRWNPENYGGITSIRVPSESIWLPDI-VLYENADGRFEGSLMTKA--IVRYNGMITWTPPASYKSACTMDVTFFPFDRQNCSMKFGSWTYDGNMVKLVLINQQVDRSDFFDN--------GEWEILSATGV-KGSRQDSHLSYPYITYSFILKRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEGEKVSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIVTIFVINVHHRSSATYHPMSPWVRSLFLQRLPHLLCMRGNTDRYHYPELEPHSPDLKPR 373
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. TrEMBL
Match: A0A4E0RUV1 (Neuronal acetylcholine receptor subunit alpha-6 OS=Fasciola hepatica OX=6192 GN=D915_003262 PE=3 SV=1) HSP 1 Score: 443.351 bits (1139), Expect = 3.178e-143 Identity = 207/302 (68.54%), Postives = 253/302 (83.77%), Query Frame = 1
Query: 265 EEGLIKRI-ENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVSYQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTLDDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKI 1167
EE L+ ++ +L +RP + S PV VNITYNV+QILAFSQ+EETLSISGWFT+ W D RL W+ + N+ +++ + +W+PD+GVMN K S +FDFS + R++V++ G VTW+HGAVLD TCPLDVSFFPFDYQTC+L++ PWQSSE+Q+++ P GSAVDNSYLPNSNVSEW+I+++ F+ KKYRSDLNV+YQY+ + IHLKRQPLYFVVLVL+PFSMLS LACLIFTLDDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMR LPV+GI+LLDQLGLLS+ATVLAVINNK+
Sbjct: 95 EERLVAQLLHRRSLVVRPNGHNNQSSNPVHVNITYNVVQILAFSQAEETLSISGWFTIKWTDPRLSWDPHAFDNIREVNVPSSKLWIPDVGVMNGKSSTDFDFSAGVRGRLTVNWEGEVTWMHGAVLDTTCPLDVSFFPFDYQTCFLILTPWQSSEQQLLLRPFSHGSAVDNSYLPNSNVSEWEIQSVHFSSKKYRSDLNVTYQYVSIGIHLKRQPLYFVVLVLVPFSMLSALACLIFTLDDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRTLPVLGIFLLDQLGLLSVATVLAVINNKL 396
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. TrEMBL
Match: A0A504YDR0 (Putative nachr subunit OS=Fasciola gigantica OX=46835 GN=FGIG_03463 PE=3 SV=1) HSP 1 Score: 443.351 bits (1139), Expect = 3.635e-143 Identity = 207/302 (68.54%), Postives = 253/302 (83.77%), Query Frame = 1
Query: 265 EEGLIKRI-ENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVSYQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTLDDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKI 1167
EE L+ ++ +L +RP + S PV VNITYNV+QILAFSQ+EETLSISGWFT+ W D RL W+ + N+ +++ + +W+PD+GVMN K S +FDFS + R++V++ G VTW+HGAVLD TCPLDVSFFPFDYQTC+L++ PWQSSE+Q+++ P GSAVDNSYLPNSNVSEW+I+++ F+ KKYRSDLNV+YQY+ + IHLKRQPLYFVVLVL+PFSMLS LACLIFTLDDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMR LPV+GI+LLDQLGLLS+ATVLAVINNK+
Sbjct: 95 EERLVAQLLHRRSLVVRPNGHNNQSSNPVHVNITYNVVQILAFSQAEETLSISGWFTIKWTDPRLSWDPHAFDNIREVNVPSSKLWIPDVGVMNGKSSTDFDFSAGVRGRLTVNWEGEVTWMHGAVLDTTCPLDVSFFPFDYQTCFLILTPWQSSEQQLLLRPFSHGSAVDNSYLPNSNVSEWEIQSVHFSSKKYRSDLNVTYQYVSIGIHLKRQPLYFVVLVLVPFSMLSALACLIFTLDDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRTLPVLGIFLLDQLGLLSVATVLAVINNKL 396
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. TrEMBL
Match: A0A183W0X7 (Neur_chan_LBD domain-containing protein OS=Trichobilharzia regenti OX=157069 GN=TRE_LOCUS6383 PE=3 SV=1) HSP 1 Score: 438.728 bits (1127), Expect = 2.156e-141 Identity = 204/302 (67.55%), Postives = 253/302 (83.77%), Query Frame = 1
Query: 265 EEGLIKRI-ENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVSYQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTLDDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKI 1167
EE L+ ++ +L +RP + + PV V+ITYNV+QIL FSQSEETLSISGWFT+ W D RL WN + ++ +S+ A ++W+PD+GVMN K S +FDFS + R++V+ G VTWLHGAVLDVTCPLDVSFFPFDYQTC+L++ PWQS E+Q++++P GSAVDNSYLPNSNVSEW+I+++ F KKYRSDLNV+YQY+ ++IHLKRQPLYF+VLVL+PFSMLS LACLIFTLDDTGDRLSVALSLVLSMTMYVVIVS+NAPRSMR LPV+GI+LLDQLGLLS+AT+LAV+NNK+
Sbjct: 32 EEKLVAQLLSRGSLTVRPNGHMNQSTNPVHVDITYNVVQILGFSQSEETLSISGWFTLRWNDPRLTWNPEEFSDIQEVSLPATNLWIPDVGVMNGKASTDFDFSAGVRGRVTVNKDGSVTWLHGAVLDVTCPLDVSFFPFDYQTCFLILVPWQSGEQQLLLHPFTHGSAVDNSYLPNSNVSEWEIQSVHFVRKKYRSDLNVTYQYVSIAIHLKRQPLYFIVLVLVPFSMLSALACLIFTLDDTGDRLSVALSLVLSMTMYVVIVSTNAPRSMRTLPVLGIFLLDQLGLLSIATILAVMNNKL 333
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. TrEMBL
Match: A0A4S2MMC4 (Neur_chan_LBD domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_000207 PE=3 SV=1) HSP 1 Score: 434.491 bits (1116), Expect = 1.065e-140 Identity = 200/302 (66.23%), Postives = 254/302 (84.11%), Query Frame = 1
Query: 265 EEGLIKRIENI-NLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVSYQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTLDDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKI 1167
EE L+ ++ N +L +RP + + PV V+ITYNVIQILAFSQ+EET+SISGWFT+ W+D RL W+ + +++ +++ + +W+PD+GVMN K S +FDFS + R+++ G VTWLHGAVLD TCPLDV+FFPFDYQTC+L++ PWQS+E+Q+++ P GSAVDNSYLPNSNVSEW+I+++ F+ +KYRSDLNV+YQY+ + IHL+RQPLYFVVLVL+PFSMLS LACLIFTLDDTGDRLSVALSLVLSMTMYVVIVS+NAPRSMR LPV+GI+LLDQLGLLS+ATVLAVINNK+
Sbjct: 15 EEKLVAQLLNRGSLTVRPNGHNNKTTSPVFVDITYNVIQILAFSQAEETMSISGWFTIKWRDPRLTWDPQEFSDIAEVNVPSGQLWIPDVGVMNGKSSTDFDFSAGVRGRLTLSSQGEVTWLHGAVLDTTCPLDVAFFPFDYQTCFLILTPWQSNEQQLLLRPFTHGSAVDNSYLPNSNVSEWEIQSVHFSSRKYRSDLNVTYQYVSIGIHLRRQPLYFVVLVLVPFSMLSALACLIFTLDDTGDRLSVALSLVLSMTMYVVIVSTNAPRSMRTLPVLGIFLLDQLGLLSIATVLAVINNKL 316
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. TrEMBL
Match: A0A4Z2CP49 (Neuronal acetylcholine receptor subunit alpha-6 isoform 3 OS=Schistosoma japonicum OX=6182 GN=EWB00_008662 PE=3 SV=1) HSP 1 Score: 438.343 bits (1126), Expect = 1.633e-140 Identity = 206/308 (66.88%), Postives = 253/308 (82.14%), Query Frame = 1
Query: 265 EEGLIKRIENI-NLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVSYQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTLDDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRYLKSL 1185
EE L+ ++ N +L +RP + + PV VNITYNV+QIL FSQSEETLSISGWFT+ W D RL WN + + +S+ ++W+PD+GVMN K S +FDFS + R++V+ G VTWLHGAVLDVTCPLDVSFFPFDYQTC+L++ PWQS E+Q+++ P GSAVDNSYLPNSNVSEW+I+++ F KKYRSD+NV+YQY+ ++IHLKRQPLYF+VLVL+PFSMLS LACLIFTLDDTGDRLSVALSLVLSMTMYVVIVS+NAPRSMR LPV+GI+LLDQLGLLS+AT+LAV+NNK+ K L
Sbjct: 89 EEKLVAQLLNRGSLTVRPNGYMNQSTNPVHVNITYNVVQILGFSQSEETLSISGWFTMRWTDPRLTWNPEEFSEIQEVSLPTTNLWIPDVGVMNGKASTDFDFSAGVRGRVTVNNDGSVTWLHGAVLDVTCPLDVSFFPFDYQTCFLILVPWQSGEQQLLLQPFTHGSAVDNSYLPNSNVSEWEIQSVHFVRKKYRSDMNVTYQYVSIAIHLKRQPLYFIVLVLVPFSMLSALACLIFTLDDTGDRLSVALSLVLSMTMYVVIVSTNAPRSMRTLPVLGIFLLDQLGLLSIATILAVMNNKLYQSKEL 396
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Cavefish
Match: chrne (acetylcholine receptor subunit gamma-like [Source:NCBI gene;Acc:103030399]) HSP 1 Score: 138.272 bits (347), Expect = 9.420e-35 Identity = 95/349 (27.22%), Postives = 180/349 (51.58%), Query Frame = 1
Query: 259 GFEEG--LIKRIENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSA------VDNSYLPNSNVSEWQIE---AIDFTPKKYRSDLNVSYQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL--DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSL--ATVLAVINNKIRYLKSLPKTKSKSHQYR--CPDFTVDSPIME 1254
G EE + + +N N +IRP H V+V + + +++ ++ EETL+ + W + W D RL WN + Y ++S I + +WLPDI + N K FD + A I D G + WL A+ TC +++++FPFD+Q C LV S +I + G VD + EW I+ A T +Y D ++ YQ + ++ ++R+PL++++ +++P +++S L L + L G +L+V++S++L+ T+++++VS P + +P+IG YL+ + + +L + V+N +R + +++ H + P F +P+++
Sbjct: 26 GNEESKLIADKFKNYNKNIRPA---RHTEDKVQVQVKLTLTNLISLNEKEETLTTNVWIEIQWNDYRLAWNTSDYHDISLIRVPYNTVWLPDIVLENNIDGK-FDVAYYANVLIYSD--GSMYWLPPAIYRSTCAIEITYFPFDWQNCTLVFRSQTYSANEIDMILAIDGDTQKPIEWVDIDPEAFTENGEWAIKHRPARKLTNTRYSPD-DLEYQEVYFNLIIQRKPLFYIINIILPCALISSLVVLAYFLPAQAGGQKLTVSISVLLAQTVFLILVSQKVPETSLSVPLIGKYLIFVMSVTTLIVTNCIVVLNFSLRSPNTHTMSRTLKHIFLEVVPRFLGMAPLVD 367
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Cavefish
Match: chrnb3a (cholinergic receptor, nicotinic, beta polypeptide 3a [Source:ZFIN;Acc:ZDB-GENE-040108-1]) HSP 1 Score: 135.191 bits (339), Expect = 5.475e-34 Identity = 94/337 (27.89%), Postives = 170/337 (50.45%), Query Frame = 1
Query: 331 HCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSS----EKQIIIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKK-YRSDLNVSYQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLA--VINNKIR---------------YLKSLPK---TKSKSHQYRCPDFTVDSPIMELRK 1263
H + + V + Q++ + + ++ + W W D +L+W+ YG ++SI + ++++WLPDI V+ F+ S + ++ V Y G +TW A +C +DV+FFPFD Q C + W + ++ V R DN EW+I +D T ++ R D SY ++ S LKR PL++ + ++IP LS L L+F L D G++LS++ S+++S+T++++++ P S + +P+IG YLL + ++ + ++ VIN R +L+ LP+ + +YR PD + SP EL++
Sbjct: 38 HANDTIAVRFGLKISQLVDVDEKNQLMTTNVWLWQEWTDYKLRWDPEDYGGITSIRVPSENIWLPDI-VLYENADGRFEGSLMTKA--IVKYDGTITWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLALVDQHVDRKDFFDN--------GEWEI--LDATGRRGSRRDGIYSYPFVTYSFILKRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTFSIIVTVFVINVHHRSSATYHPMAPWVKSLFLQRLPRLLCMHGHTDRYRYPDMELHSP--ELKR 359
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Cavefish
Match: chrnb3a (cholinergic receptor, nicotinic, beta polypeptide 3a [Source:ZFIN;Acc:ZDB-GENE-040108-1]) HSP 1 Score: 134.806 bits (338), Expect = 9.633e-34 Identity = 94/337 (27.89%), Postives = 170/337 (50.45%), Query Frame = 1
Query: 331 HCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSS----EKQIIIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKK-YRSDLNVSYQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLA--VINNKIR---------------YLKSLPK---TKSKSHQYRCPDFTVDSPIMELRK 1263
H + + V + Q++ + + ++ + W W D +L+W+ YG ++SI + ++++WLPDI V+ F+ S + ++ V Y G +TW A +C +DV+FFPFD Q C + W + ++ V R DN EW+I +D T ++ R D SY ++ S LKR PL++ + ++IP LS L L+F L D G++LS++ S+++S+T++++++ P S + +P+IG YLL + ++ + ++ VIN R +L+ LP+ + +YR PD + SP EL++
Sbjct: 52 HANDTIAVRFGLKISQLVDVDEKNQLMTTNVWLWQEWTDYKLRWDPEDYGGITSIRVPSENIWLPDI-VLYENADGRFEGSLMTKA--IVKYDGTITWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLALVDQHVDRKDFFDN--------GEWEI--LDATGRRGSRRDGIYSYPFVTYSFILKRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTFSIIVTVFVINVHHRSSATYHPMAPWVKSLFLQRLPRLLCMHGHTDRYRYPDMELHSP--ELKR 373
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Cavefish
Match: chrnb3b (neuronal acetylcholine receptor subunit non-alpha-2 [Source:NCBI gene;Acc:103031723]) HSP 1 Score: 134.42 bits (337), Expect = 1.250e-33 Identity = 97/358 (27.09%), Postives = 174/358 (48.60%), Query Frame = 1
Query: 265 EEGLIKRI-ENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIII----YPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVSYQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLA--VINNKIR---------------YLKSLPK---TKSKSHQYRCPDFTVDSPIMELR 1260
E+ L++ + + +RP H + V+V + Q++ + + ++ + W W D +L+WN YG ++ I + ++ +WLPDI V+ F+ S + ++ I Y G VTW A C +DV+FFPFD Q C + W + + Y V R DN EW+I + K R D +SY ++ S LKR PL++ + ++IP LS L L+F L D G+++S++ S+++S+T++++++ P S + +P+IG YLL + ++L+ ++ VIN R +L+ LP + + +Y P+ SP ++ R
Sbjct: 34 EDALLRDLFQGYQRWVRP---TQHSNNTVRVRFGLKISQLVDVDEKNQLMTTNVWLWQEWIDYKLRWNPEDYGGITFIRVPSESIWLPDI-VLYENADGRFEGSLMTKAIIK--YNGAVTWTPPASYKSACTMDVTFFPFDRQNCSMKFGSWTYDGTMVDMVLMNYQVDRRDFFDN--------GEWEILSATGM-KGNRRDGTLSYPFVTYSFILKRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEGEKVSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIVTVFVINVHHRSSATYHPMSPWVRSLFLQRLPHLLCMRGHTDRYHYPELEPQSPELKPR 376
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Cavefish
Match: chrnb3b (neuronal acetylcholine receptor subunit non-alpha-2 [Source:NCBI gene;Acc:103031723]) HSP 1 Score: 134.42 bits (337), Expect = 1.324e-33 Identity = 97/358 (27.09%), Postives = 174/358 (48.60%), Query Frame = 1
Query: 265 EEGLIKRI-ENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIII----YPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVSYQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLA--VINNKIR---------------YLKSLPK---TKSKSHQYRCPDFTVDSPIMELR 1260
E+ L++ + + +RP H + V+V + Q++ + + ++ + W W D +L+WN YG ++ I + ++ +WLPDI V+ F+ S + ++ I Y G VTW A C +DV+FFPFD Q C + W + + Y V R DN EW+I + K R D +SY ++ S LKR PL++ + ++IP LS L L+F L D G+++S++ S+++S+T++++++ P S + +P+IG YLL + ++L+ ++ VIN R +L+ LP + + +Y P+ SP ++ R
Sbjct: 34 EDALLRDLFQGYQRWVRP---TQHSNNTVRVRFGLKISQLVDVDEKNQLMTTNVWLWQEWIDYKLRWNPEDYGGITFIRVPSESIWLPDI-VLYENADGRFEGSLMTKAIIK--YNGAVTWTPPASYKSACTMDVTFFPFDRQNCSMKFGSWTYDGTMVDMVLMNYQVDRRDFFDN--------GEWEILSATGM-KGNRRDGTLSYPFVTYSFILKRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEGEKVSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIVTVFVINVHHRSSATYHPMSPWVRSLFLQRLPHLLCMRGHTDRYHYPELEPQSPELKPR 376
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Sea Lamprey
Match: chrna3 (cholinergic receptor, nicotinic, alpha 3 [Source:ZFIN;Acc:ZDB-GENE-070822-1]) HSP 1 Score: 129.798 bits (325), Expect = 1.325e-32 Identity = 79/296 (26.69%), Postives = 156/296 (52.70%), Query Frame = 1
Query: 298 NLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVS---YQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRY 1173
N +IRP + S PV V ++ Q++ + + ++ + W W D + QWN + + I + + +W PDI + N + + DF +++ + Y G V W+ A+ +C +DV++FPFDYQ C + W + +I + V G+ ++ S EW I ID K+ N Y I S++++R PL++ + ++IP ++S L L+F L D G+++++++S++LS+T+++++++ P + +P+IG YLL + ++L+ V+ + + Y
Sbjct: 20 NPYIRPVF---NVSDPVIVRFEVSMSQLVKLDEVNQIMATNLWLKHTWNDYKFQWNPGQFEGMEYIRVPSDKIWKPDIVLYN---NADGDFQVEGKTKALLKYDGTVMWMPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWTYDKAKIDL--VLVGTKINLKDFWESG--EWVI--IDVPGYKHDIKYNCCEQIYPDITYSVYVRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLSISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITIFVLNVHY 303
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Sea Lamprey
Match: chrnb3b (cholinergic receptor, nicotinic, beta 3b (neuronal) [Source:ZFIN;Acc:ZDB-GENE-030102-4]) HSP 1 Score: 128.642 bits (322), Expect = 1.859e-32 Identity = 97/349 (27.79%), Postives = 170/349 (48.71%), Query Frame = 1
Query: 262 FEEGLIKR-IENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQI----IIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKK-YRSDLNVSYQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLA--VINNKIR---------------YLKSLPK---TKSKSHQYRCPD 1227
E+ L+KR +++ +RP D S V+V + Q++ + + ++ + W W D+ L+WN YG ++SI + A +WLPDI V+ F+ S + ++ + D G + W A+ +C +DV+FFPFD Q C + W + + V RG DN EW E ++ T K R D + Y YI S ++R PL++ + +++P LS L +F L D G+++S+ S+++S+T++++++ P S + +P+IG YLL + ++L+ ++ VIN R +L LPK +S +Y PD
Sbjct: 34 LEDRLLKRMLKDYQKWVRP---VDKLSDTVEVKFGLGIAQLVDVDEKNQLMTTNVWLKQEWVDINLRWNPDDYGGINSIRVPASSIWLPDI-VLYDNADGRFEGSIVTKAVVKHD--GRIKWTPPAIYKSSCTIDVTFFPFDQQNCSMKFGSWTYDGTLVDLIMVNSDVDRGEYFDN--------GEW--EFLNATGNKGVRLDGHRFYPYITYSFVIRRLPLFYTLFLIVPCLGLSFLTVFVFYLPSDEGEKISLCTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIITVFVINVHHRSSSTHHPMAPWVRQLFLHKLPKILCMRSHVDRYTAPD 366
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Sea Lamprey
Match: chrnb1l (cholinergic receptor, nicotinic, beta 1 (muscle) like [Source:ZFIN;Acc:ZDB-GENE-060811-1]) HSP 1 Score: 115.546 bits (288), Expect = 9.190e-28 Identity = 79/281 (28.11%), Postives = 150/281 (53.38%), Query Frame = 1
Query: 346 VKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQI-IIYPVQ------RGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVS---YQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVI 1155
V V + + Q+++ + +++S ++ W+D RL W+ Y NL SI + K +WLPDI + N + NFDF + VDYTG V W+ ++ +C + V +FPFD+Q C +V + +I + Y + R +D S P S EWQI+ K R + N YQ I + ++R+PL++++ +++P +++ A F L D G+++ + +S++L++T+++++++ P + +PVI YL+ + +++ +L VI
Sbjct: 51 VTVRLGMTLSQLISLPACQPDMTLSRLISLSWEDPRLSWDPRNYDNLRSIRLSPKRVWLPDIALSN-NNDGNFDFGLYVH--VLVDYTGAVRWVPPSIYRSSCGMQVKYFPFDWQNCSMVFQSFTYDTSEINLEYALDEHRQEIRHIIIDESTFPVSG--EWQIKH-----KPSRKNTNPRDPLYQDITFYLIMERKPLFYIINIVVPCILITICAVFTFYLPPDAGEKMGLCISVLLALTVFLLLLADKVPETSLGVPVIVNYLMFTMVIVTACVILTVI 321
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Sea Lamprey
Match: chrna2a (cholinergic receptor, nicotinic, alpha 2a (neuronal) [Source:ZFIN;Acc:ZDB-GENE-040108-2]) HSP 1 Score: 110.923 bits (276), Expect = 5.628e-26 Identity = 73/256 (28.52%), Postives = 143/256 (55.86%), Query Frame = 1
Query: 394 QSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDNSYLPNSNVSEWQI-EAID-FTPKKYRSDLNVSYQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAV 1152
+ + ++ + W W D +LQW+ A Y N++SI + ++ +W+PDI + N + + DF+ ++ + +TG V W A+ +C +DV+FFPFD Q C + W + +I + + R + + + EW I A+ + KKY V Y I S ++R PL++ + ++IP ++S L L+F L D G+++++ +S++LS+T+++++++ P + +P+IG YLL + ++L+ V+ V
Sbjct: 15 EKNQMMTTNVWLKQEWDDYKLQWDPAEYENVTSIRVPSELIWVPDIVLYN---NADGDFAVTHMTKAHLFHTGRVRWKPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVSMARDVDLKDYW----ESGEWAIVHAVGTYNTKKYDCCPQV-YPDITYSFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITV 262
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Sea Lamprey
Match: htr3a (5-hydroxytryptamine (serotonin) receptor 3A [Source:ZFIN;Acc:ZDB-GENE-071012-5]) HSP 1 Score: 92.8189 bits (229), Expect = 2.643e-20 Identity = 63/271 (23.25%), Postives = 127/271 (46.86%), Query Frame = 1
Query: 340 KPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGV---MNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVSYQYIRVSIH--LKRQPLYFVVLVLIPFSMLSGLACLIFTLDDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLA 1137
+P+ V I + IL + + L+ W+ W D LQW+ Y + ISI ++W+PDI + ++V S + + + + Y G V + C LD+ FPFD Q C L W + I + + + N EW++ ++ P + L ++ + I+ ++R+PL++VV +++P + L + + D+G+R+S ++L+L ++++++V P + P+I +Y + + LL ++
Sbjct: 58 QPIIVAIDVMLYAILNVDEKNQVLTAYIWYRQRWTDEFLQWDPVQYDGIEQISIPTNNIWVPDIMISEFVDVGKSPDIGY-------VYLSYNGTVMNYKPLQVVSACSLDIYSFPFDVQNCTLTFTSWLHTSNDINLTLWRTTEEIKEDKSIFLNFGEWELISV---PNELLHPLYGENRFSELKIYVVIRRRPLFYVVNLIMPSAFLMVMDAGFYLPPDSGERVSFKITLLLGYSVFLIVVQDTLPATPIGTPLIAVYFVVCMALLVIS 318
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Nematostella
Match: EDO37425 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFX0]) HSP 1 Score: 120.553 bits (301), Expect = 1.933e-30 Identity = 75/293 (25.60%), Postives = 144/293 (49.15%), Query Frame = 1
Query: 304 HIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKK--YRSDLNVSYQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTLD-DTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRY 1173
IRP ++ S+PV V + + ++ + ++ L+ W W + R+QW+ ++G + +++ D+W PDI + N + + + V Y G W + C + V FPFD Q C L WQ +I ++ V+ +DN+ + N EW + + T Y +V Y I + L+R+ L+++ ++IP +++ LA F + + G+R+S ++++LSMT+++++V+ + P + LP I +Y + L++LA V I K+ Y
Sbjct: 16 RIRP---VENTSRPVNVTMDMTLSNVIDIDEKQQILTSCVWMRQEWINERMQWDPKLFGGIKDVTLHTSDIWQPDIVLYNNVFEEFDGRLDHVSTLVRVYYNGSTHWNAPFIFKTLCKIQVKNFPFDLQECTLKFGSWQYDSSEIDLHYVKTEGKLDNTRVRN---GEWDVIRVKITRNALSYPCCPDVVYPDITFIVQLRRRSLFYIFNLIIPNFLIALLAFFSFYIPIECGERISFVITVLLSMTVFLLLVAESIPPTSEALPAIALYYTSSMILVALALVATGITLKVNY 302
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Nematostella
Match: EDO32053 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SW63]) HSP 1 Score: 119.398 bits (298), Expect = 7.897e-30 Identity = 80/307 (26.06%), Postives = 162/307 (52.77%), Query Frame = 1
Query: 265 EEGLIKRI-ENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNV------SYQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQL--GLLSLATVLAVI 1155
E L+K + +N + RP + + + PV++ + + Q++ ++ ++ L+I+ W WKD L+WN +G + SI+I +W PD+ + N + + + + V++ G TWL A++ C +DV FFPFD Q+C L W +I I+ +++ S +D S+ EW ++ R D+ + Y + +I L+R+ +++V +++P +++ L+ F L ++G+R+S ++++L+M++Y+++V+ N PRS +P++ + + + LSLA VI
Sbjct: 1 EPALLKYLLQNYSKDARPVL---NVNDPVQLKLGIMLRQVIDLNERDQILTINVWIRQYWKDHLLKWNPDDFGGIKSINIAPDRVWKPDVLLYNRTDLRFGSLNNKIDTNVIVNHDGSTTWLAPAIIKSECKIDVRFFPFDVQSCELTFGSWTHDGLKIDIH-LKQESGIDTENF--SDNREWFLKG-----TSGRRDVKMYICCPEPYPTVTYTIILRRRAMFYVFNMVLPTGVIALLSLFSFYLPPNSGERVSFVITVLLAMSVYLIMVTENIPRST-DIPLVSKFFMASMIQIALSLAATCVVI 295
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Nematostella
Match: EDO49045 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHV9]) HSP 1 Score: 118.627 bits (296), Expect = 1.773e-29 Identity = 84/306 (27.45%), Postives = 157/306 (51.31%), Query Frame = 1
Query: 265 EEGLIKRIENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDNSYLPNSNVSEWQIE--AIDFTPKKYRSDLNVSYQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTLD-DTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRY 1173
E+ L++R+ N + P+ + V ++IT+N I+ + + LS S W W L W+ A YG ++ I + ++ +W PD + N + +R+ V +G V W V C +DV+ FPFD Q C + WQ + ++ + +R + V ++ + N EW +E AI+ Y+ N Y I IH++R+ L++VV +++P +++ LA F + + G+R+S ++++LSMT+++++V+ + P + +PVIG+Y + + LA V I+ +I Y
Sbjct: 12 EQRLLERLINASGSGVRPILDLARPTNVTLDITFN--SIIDVDEKHQILSSSVWIRQSWIAETLSWDPAEYGGVNQIVVSSQLLWQPDTVLYNNIFEEFDSRLDTTVTRVRVYSSGFVYWAMPYVFKTMCKIDVTDFPFDSQRCPITFGAWQYDQNEVNLINNKRLATVASTRVENG---EWTVEKVAIERRVIFYQCCPNQPYPEISFVIHMQRRSLFYVVNLVLPNFLITLLAFFSFFIPVECGERMSFVITVLLSMTVFLLLVAESIPPTSEAVPVIGVYYTFCIVEVFLALVATGISFRINY 312
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Nematostella
Match: EDO36173 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJF7]) HSP 1 Score: 115.161 bits (287), Expect = 1.708e-28 Identity = 71/286 (24.83%), Postives = 140/286 (48.95%), Query Frame = 1
Query: 331 HCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMN---VKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVS-YQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTLD-DTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRY 1173
H S P+ V+ + +++ + + L W T W + L WN++ YG + SI + D+W+PD + N V F T + V+ G+ TW+ A +C LDV+FFPFD Q C +V W + + + + + + + + N +W++E I + + I S L+R PLY V+ V++P +++ L + F + + G+R+ + ++++L+M++Y+ +V+ + P + +P++GIY + + + A V + + Y
Sbjct: 28 HPSLPLNVSFNMQLSKLVDLNTKSQILQTDVWITQKWVNPFLTWNVSEYGGVHSIHVSPLDVWVPDTVLYNRCVVLSGSVEKFKT----DVVVESDGLCTWMSPATFKSSCVLDVTFFPFDTQVCSMVFGSWTYDTRLLRLELMAQLHSNADHFTVN---GDWKVENISLRQRDTNYTCCAHPFSDIVFSFALERLPLYHVIYVVLPCVIIAALTLVCFYVPVECGERIGLCITILLAMSVYLFVVAQSLPENSNTIPLLGIYYMATMCQVGAAIVATAVVLRCHY 306
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Nematostella
Match: EDO46124 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RR86]) HSP 1 Score: 115.546 bits (288), Expect = 1.313e-27 Identity = 70/279 (25.09%), Postives = 146/279 (52.33%), Query Frame = 1
Query: 337 SKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVSY-QYIRV--SIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIY---LLDQLGLLSLATVLAV 1152
S+P+KV Q++ + ++ W W + RL+W+ + YG +S+++ +WLPDI + N +S +++ + TG + W ++ C +D+++FPFD Q C LV W + + + +++ + Y PN Q E + K+ + Y YI V ++H++R+PL+FV+ +++P +L+ L+ F+L +G+R+++ ++L+L +T+Y++I + N P++ P+I + +L ++ + LAT + +
Sbjct: 55 SQPIKVIFDIAFAQLVELDSKNQIMTSYIWVRQFWSNTRLRWDPSKYGGQTSVNLSPHLIWLPDIVLYNNINSNTIGEMFKFDTKVVLHNTGAIEWYAPTLVKSICKIDITYFPFDKQNCSLVFGSWTYTS-EFLSLDIKQKEPDLSKYTPNG-----QWEMMHAEVKRNVVKYSCCYWPYIDVTYTVHIRRRPLFFVLNLILPCILLATLSVFSFSLPPGSGERIALVITLLLGLTVYMLIFTENIPKTSEVTPLINKFFNVVLFEVAICLLATSITL 327
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Medaka
Match: chrnb3b (neuronal acetylcholine receptor subunit non-alpha-2 [Source:NCBI gene;Acc:101162690]) HSP 1 Score: 134.42 bits (337), Expect = 1.458e-33 Identity = 91/326 (27.91%), Postives = 163/326 (50.00%), Query Frame = 1
Query: 346 VKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVSYQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLA--VINNKIR---------------YLKSLPK---TKSKSHQYRCPDFTVDSPIMELR 1260
V+V + Q++ + + ++ + W W D +L+WN YG ++SI + ++++WLPDI + K F ++ V + G VTW+ A C +DV+FFPFD Q C + W + + V S VD ++ EW+I + K R D Y +I S LKR PL++ + ++IP LS L L+F L D G++LS++ S+++S+T++++++ P S + +P+IG YLL + ++L+ ++ VIN R +L+ LP+ + + +Y P+ +SP ++ R
Sbjct: 59 VRVRFGLKISQLVDVDEKNQLMTTNVWLRQEWIDYKLRWNPDKYGGITSIRVPSENIWLPDIVLYENADGK---FEGSLMTKAIVKFNGAVTWMPPASYKSACTMDVTFFPFDRQNCSMKFGSWTYDGNMVDL--VLMDSQVDRKDFFDNG--EWEILSAT-GAKGNRKDGLYFYPFITCSFILKRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIVTVFVINVHHRSSATYHPMSPWVRSLFLQKLPRLLCMRGHADRYHYPELAPESPALKSR 376
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Medaka
Match: chrna6 (neuronal acetylcholine receptor subunit alpha-3 [Source:NCBI gene;Acc:101162933]) HSP 1 Score: 135.576 bits (340), Expect = 1.752e-33 Identity = 84/303 (27.72%), Postives = 159/303 (52.48%), Query Frame = 1
Query: 298 NLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVS---YQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRYLKSLPKT 1194
N IRP ++ S PV V ++ Q++ + + + + W VW D +L+W A Y + I + + +W PDI + N + DF +++ + + G +TW+ A+ +CP+D+++FPFDYQ C + W + +I + V GS V+ S EW+I ID K+ N Y I S +++R PL++ + ++IP ++S L L+F L D G+++++ +S++LS+T+++++++ P + +P+IG YLL + ++L+ V+ V + Y + T
Sbjct: 75 NQFIRP---VENVSDPVTVEFEVSISQLVKVDEVNQIMETNLWLRHVWNDYKLKWTPAEYDGIEFIRVPSNRIWRPDIVLYN---NAVGDFLVADKTKALLKFDGTITWVPPAIFKSSCPMDITYFPFDYQNCSMKFGSWTYDKAKIDL--VLIGSKVNLKDFWESG--EWEI--IDAPGYKHDIKYNCCEEIYTDITYSFYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPMTHT 365
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Medaka
Match: ENSORLT00000017941.2 (neuronal acetylcholine receptor subunit alpha-3-like [Source:NCBI gene;Acc:101168601]) HSP 1 Score: 133.265 bits (334), Expect = 3.584e-33 Identity = 84/315 (26.67%), Postives = 165/315 (52.38%), Query Frame = 1
Query: 265 EEGLIKRI-ENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVS---YQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRYLKSLPKT 1194
E+ L +++ N IRP ++ S PV V ++ Q++ + + + + W +W D +L+W A + + I + + +W PDI + N + DF +++ + + G +TW+ A+ +CP+D+++FPFDYQ C + W + +I + V GS V+ S EW+I ID K+ N Y I S +++R PL++ + ++IP ++S L L+F L D G+++++ +S++LS+T+++++++ P + +P+IG YLL + ++L+ V+ V + Y + T
Sbjct: 29 EDRLFRKLFRRYNQFIRP---VENVSDPVTVEFEVSISQLVKVDEVNQIMETNLWLRHIWNDYKLRWTPAEFDGIEFIRVPSNKIWRPDIVLYN---NAVGDFLVEDKTKALLKFDGTITWVPPAIFKSSCPMDITYFPFDYQNCSMKFGSWTYDKAKIDL--VLIGSKVNLKDFWESG--EWEI--IDAPGYKHDIKYNCCEEIYPDITYSFYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPMTHT 331
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Medaka
Match: chrna3 (neuronal acetylcholine receptor subunit alpha-3 [Source:NCBI gene;Acc:101159658]) HSP 1 Score: 134.035 bits (336), Expect = 4.062e-33 Identity = 86/307 (28.01%), Postives = 163/307 (53.09%), Query Frame = 1
Query: 292 NINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVS---YQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRYLKSLPKTKS 1200
N N +IRP ++ S PV V ++ Q++ + + + + W +W D +L+WN +G + I + + +W PDI + N + DF +++ + + G VTW+ A+ +C +DV++FPFDYQ C + W + +I + V GS ++ S EW I ID K+ N Y I S++++R PL++ + ++IP ++S L L+F L D G+++++ +S++LS+T+++++++ P + +P+IG YLL + ++L+ V+ V + Y PKT +
Sbjct: 38 NYNQYIRP---VENVSDPVIVQFEVSMSQLVKVDEVNQIMETNLWLRHIWNDYKLKWNPKEFGGVEFIRVPSNRIWKPDIVLYN---NAVGDFQVDDKTKALLRFNGDVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWTYDKAKIDL--VLIGSTINLKDFWES--GEWTI--IDAPGYKHDIKYNCCEEIYTDITYSLYIRRLPLFYTINMIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHY--RTPKTHT 330
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Medaka
Match: chrnb3a (neuronal acetylcholine receptor subunit non-alpha-3 [Source:NCBI gene;Acc:101168098]) HSP 1 Score: 130.183 bits (326), Expect = 3.875e-32 Identity = 90/337 (26.71%), Postives = 169/337 (50.15%), Query Frame = 1
Query: 331 HCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQI----IIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKK-YRSDLNVSYQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTL-DDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLA--VINNKIR---------------YLKSLPK---TKSKSHQYRCPDFTVDSPIMELRK 1263
H + + V + Q++ + + ++ + W W D++L+WN YG ++SI + ++ +WLPDI V+ F+ S + ++ + D G +TW A +C +DV+FFPFD Q C + W + + + V R DN EW+I ++ T ++ R D Y ++ S LKR PL++ + ++IP LS L L+F L D G++LS++ S+++S+T++++++ P S + +P+IG YLL + ++ + ++ VIN R +L+ LP+ + + +Y PD + SP ++ R+
Sbjct: 54 HANDTITVRFGLKISQLVDVDEKNQLMTTNVWLWQEWIDVKLKWNPDDYGGITSIRVPSETIWLPDI-VLYENADGRFEGSLMTKAIVRWD--GTITWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGNMVDLVLVDHYVDRKDFFDN--------GEWEI--LNATGQRGSRRDEMYWYPFLTYSFILKRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTFSIIVTVFVINVHHRSSATYHPMAPWVKSLFLQKLPRLLCMRGHTDRYHFPDIEMRSPELKTRR 377
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Planmine SMEST
Match: SMESG000052669.1 (SMESG000052669.1) HSP 1 Score: 879.782 bits (2272), Expect = 0.000e+0 Identity = 481/483 (99.59%), Postives = 481/483 (99.59%), Query Frame = 1
Query: 145 MIFSRRITDDAVFILQRIXXXXXXXXXXXXXXKETTQIGFEEGLIKRIENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVSYQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTLDDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRYLKSLPKTKSKSHQYRCPDFTVDSPIMELRKYRMSCNNSFGYXXXXXXXXXXXXXXXXXXXXLSKPNNVDNEISESFPNIPLNYSEFSSEKYIRKYVYRELADKLDKFQMVIYLFISFINGIFCLLIMPRYFQNSTLNPPD 1593
MIFSRRITDDAVFILQRISFFFQLLLVVSVFFKETTQIGFEEGLIKRIENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWN AVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVSYQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTLDDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRYLKSLPKTKSKSHQYRCPDFTVDSPIMELRKYRMSCNNSFGYKNSKNFRFSIKSSFKSSKENLSKPNNVDNEIS SFPNIPLNYSEFSSEKYIRKYVYRELADKLDKFQMVIYLFISFINGIFCLLIMPRYFQNSTLNPPD
Sbjct: 1 MIFSRRITDDAVFILQRISFFFQLLLVVSVFFKETTQIGFEEGLIKRIENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNQAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVSYQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTLDDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRYLKSLPKTKSKSHQYRCPDFTVDSPIMELRKYRMSCNNSFGYKNSKNFRFSIKSSFKSSKENLSKPNNVDNEISGSFPNIPLNYSEFSSEKYIRKYVYRELADKLDKFQMVIYLFISFINGIFCLLIMPRYFQNSTLNPPD 483
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Planmine SMEST
Match: SMESG000043840.1 (SMESG000043840.1) HSP 1 Score: 562.377 bits (1448), Expect = 0.000e+0 Identity = 294/468 (62.82%), Postives = 355/468 (75.85%), Query Frame = 1
Query: 259 GFEEGLIKRIENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVSYQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTLDDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIRYLKSLPKTKSKSH--QYRCPDFTVDSPIMELRKYRMSCNNSFGYXXXXXXXXXXXXXXXXXXXXLSKPNNVDNEISESFPN--IPLNYSEFSS-------------EKYIRKY------VYRELADKLDKFQMVIYLFISFINGIFCLLIMPRYFQNSTLNPPD 1593
+EE L+ + NL +RP C HC+ PV VNITYNVIQILAFSQ+EET+SISGWFT+VW D RL+WN YGNL+++SI A+DMWLPDIG+MNVK+SKNFDFSTIAQSRISV+ G +TWLHGA+LDVTCPLDV FFPFD QTCYLVI PWQSS+KQ++I+P Q GSAVDNSYLPNSNVSEW+I A+ F K+YRSDLNV+YQYIRVSIHL+RQPLYFVVLVLIPFSMLSGLACLIFTL+DTGDRLSVALSLVLSMTMYVVIVSSNAPRSMR LPVIGIYLLDQLGLLSLATVLAVINNK+RY K P++KS+ YRCP++ DSPI++L+ + N++ ++K N D S+S+ N + +N++ +S ++ Y +Y++LAD+ DK +MV YL ISFING+FCL+++P YFQ+ LNPPD
Sbjct: 24 SYEEELLNILRKRNLKVRPNPCRSHCANPVNVNITYNVIQILAFSQAEETMSISGWFTIVWSDNRLEWNSEKYGNLNAVSIPAQDMWLPDIGIMNVKNSKNFDFSTIAQSRISVESDGRITWLHGAILDVTCPLDVRFFPFDVQTCYLVITPWQSSDKQMLIHPYQLGSAVDNSYLPNSNVSEWEIRAVHFKRKRYRSDLNVTYQYIRVSIHLRRQPLYFVVLVLIPFSMLSGLACLIFTLEDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRSLPVIGIYLLDQLGLLSLATVLAVINNKVRYFKVSPESKSRKQPTGYRCPEYNNDSPIIQLQNSKNRMNDA--------------------NHKINKKFNADYNFSKSYANNSVRVNFNVANSLSRNSSPSTSLSSTDFLPLYQPRGVNIYKDLADRFDKIEMVTYLIISFINGVFCLIVVPSYFQDVNLNPPD 471
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Planmine SMEST
Match: SMESG000077071.1 (SMESG000077071.1) HSP 1 Score: 474.552 bits (1220), Expect = 1.322e-164 Identity = 245/435 (56.32%), Postives = 308/435 (70.80%), Query Frame = 1
Query: 301 LHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVSYQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTLDDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKI----RYLKSLPKTKSKSHQ----YRCPDFTVDSPIMELRKYR-MSCNNSFGYXXXXXXXXXXXXXXXXXXXXLSKPNNVDNEISESFPNIPLNYSEFSSEKYIRKYVYRELADKLDKFQMVIYLFISFINGIFCLLIMPRYFQNST 1578
L +RP C HC+ PV VNITYNVIQILAFSQ+EETL ISGWFTV W D RL+WN YG++ ++S+ +K++W PD+GVMN K S++FDFS I QSRISV +TG + WLHGA+LDVTCPLDV +FPFD QTCYL++ PWQSS KQ++I PVQ GSAVDNSYLPNSNVSEW+I + F+ K Y S ++ YQ+I +SI LKRQPLYF+VLVL+PFSMLSGLACLIFTL DTGDRL+VALSLVLSMTMYVVIVS+NAPRSMR LPV+G+YLL+QLGLLS+AT+LAV+NNK+ RY + ++ ++ YRC D +SPI LRK ++CN + + + + P N ++S +S YIR LADK+D ++ IYL +S +N I CLLIMPR Q ++
Sbjct: 9 LTVRPNACRVHCNNPVIVNITYNVIQILAFSQAEETLKISGWFTVEWMDFRLRWNPKYYGDIDTVSLNSKNLWRPDVGVMNGKASEDFDFSNIPQSRISVKHTGNIYWLHGAILDVTCPLDVRYFPFDKQTCYLILTPWQSSIKQMVIEPVQHGSAVDNSYLPNSNVSEWEIVDVKFSKKTYESQISEVYQFISISISLKRQPLYFIVLVLVPFSMLSGLACLIFTLSDTGDRLTVALSLVLSMTMYVVIVSTNAPRSMRTLPVLGVYLLNQLGLLSVATILAVVNNKLRDNNRYSDMISTNPNEIYRGPMNYRCYDQCNESPIKSLRKQSIIACNYAMRH-----------------RATVCLPGNGGLKVS-------------NSASYIR------LADKMDHIELTIYLILSLLNAIVCLLIMPRVSQKTS 407
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Planmine SMEST
Match: SMESG000077071.1 (SMESG000077071.1) HSP 1 Score: 474.552 bits (1220), Expect = 1.567e-164 Identity = 245/435 (56.32%), Postives = 308/435 (70.80%), Query Frame = 1
Query: 301 LHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVSYQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTLDDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKI----RYLKSLPKTKSKSHQ----YRCPDFTVDSPIMELRKYR-MSCNNSFGYXXXXXXXXXXXXXXXXXXXXLSKPNNVDNEISESFPNIPLNYSEFSSEKYIRKYVYRELADKLDKFQMVIYLFISFINGIFCLLIMPRYFQNST 1578
L +RP C HC+ PV VNITYNVIQILAFSQ+EETL ISGWFTV W D RL+WN YG++ ++S+ +K++W PD+GVMN K S++FDFS I QSRISV +TG + WLHGA+LDVTCPLDV +FPFD QTCYL++ PWQSS KQ++I PVQ GSAVDNSYLPNSNVSEW+I + F+ K Y S ++ YQ+I +SI LKRQPLYF+VLVL+PFSMLSGLACLIFTL DTGDRL+VALSLVLSMTMYVVIVS+NAPRSMR LPV+G+YLL+QLGLLS+AT+LAV+NNK+ RY + ++ ++ YRC D +SPI LRK ++CN + + + + P N ++S +S YIR LADK+D ++ IYL +S +N I CLLIMPR Q ++
Sbjct: 7 LTVRPNACRVHCNNPVIVNITYNVIQILAFSQAEETLKISGWFTVEWMDFRLRWNPKYYGDIDTVSLNSKNLWRPDVGVMNGKASEDFDFSNIPQSRISVKHTGNIYWLHGAILDVTCPLDVRYFPFDKQTCYLILTPWQSSIKQMVIEPVQHGSAVDNSYLPNSNVSEWEIVDVKFSKKTYESQISEVYQFISISISLKRQPLYFIVLVLVPFSMLSGLACLIFTLSDTGDRLTVALSLVLSMTMYVVIVSTNAPRSMRTLPVLGVYLLNQLGLLSVATILAVVNNKLRDNNRYSDMISTNPNEIYRGPMNYRCYDQCNESPIKSLRKQSIIACNYAMRH-----------------RATVCLPGNGGLKVS-------------NSASYIR------LADKMDHIELTIYLILSLLNAIVCLLIMPRVSQKTS 405
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Planmine SMEST
Match: SMESG000061997.1 (SMESG000061997.1) HSP 1 Score: 436.417 bits (1121), Expect = 4.120e-148 Identity = 237/480 (49.38%), Postives = 328/480 (68.33%), Query Frame = 1
Query: 250 TQIGFEEGLIKRI-ENINLHIRPPVCEDHCSKPVKVNITYNVIQILAFSQSEETLSISGWFTVVWKDLRLQWNLAVYGNLSSISILAKDMWLPDIGVMNVKHSKNFDFSTIAQSRISVDYTGVVTWLHGAVLDVTCPLDVSFFPFDYQTCYLVINPWQSSEKQIIIYPVQRGSAVDNSYLPNSNVSEWQIEAIDFTPKKYRSDLNVSYQYIRVSIHLKRQPLYFVVLVLIPFSMLSGLACLIFTLDDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRRLPVIGIYLLDQLGLLSLATVLAVINNKIR------YLKSLPKTKSKSHQY---RCP---DFTVDSPIMELR------KYRMSCNNSFGYXXXXXXXXXXXXXXXXXXXXLSKPNN---------------------VDNEISESFPNI-PLNYSEFSSEKYIRKYVY-RELADKLDKFQMVIYLFISFINGIFCLLIMPRY 1563
+ G EE LI ++ + +L +RP C C+ V VNITYNVIQILAFSQ+EET SISGWFT+ W+D RL W+ GN++ + + ++ +WLPD+GVMN +++K+FDFS +QSR+SV + G VTW+HG +LDV+CPLDVS+FPFD QTCY+++ PWQS KQI++ PVQ GS VDNSYLPNSN+SEW I + F K Y S +N++YQYI +SI ++RQPLYF++LVL+PFSMLSGLACLIFTLDD+GDRL+VALSLVLSMTMYVVIVSSNAPRSMR LPV+ IYLL+QLGLLS++TVLAV+N K+R + + + ++ + Y P D+ DSP+ L+ +Y+ + + N+++ S ++ +N+ K N+ D+E ++ P L S+ + + IR+ Y ++LA+KLD++++ IYLFIS IN I CL++MP Y
Sbjct: 30 SSFGDEEKLITQLMKRHSLKVRPTACF-QCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLDDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREKYRLSFWQDYQQARTIFNGYYLEESPLMTDYCSDSPLATLKRAWQSQRYKNTKTETIFNSNAEDNLKSTQAYNSHRFKNIVKENDNPKSQPIKTNKDDRKHPPKSSFDDEGNKKRPFFNELFDSDQNHKGNIRQQRYYKKLANKLDRWELAIYLFISLINAIICLVLMPHY 508 The following BLAST results are available for this feature:
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30021152 ID=SMED30021152|Name=Neuronal acetylcholine receptor subunit alpha-6|organism=Schmidtea mediterranea sexual|type=transcript|length=1698bpback to top protein sequence of SMED30021152-orf-1 >SMED30021152-orf-1 ID=SMED30021152-orf-1|Name=SMED30021152-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=484bp MIFSRRITDDAVFILQRISFFFQLLLVVSVFFKETTQIGFEEGLIKRIENback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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