SERPIN domain-containing protein
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30021146 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 5
Homology
BLAST of SERPIN domain-containing protein vs. Ensembl Human
Match: SERPINB13 (serpin family B member 13 [Source:HGNC Symbol;Acc:HGNC:8944]) HSP 1 Score: 181.03 bits (458), Expect = 2.709e-52 Identity = 115/382 (30.10%), Postives = 206/382 (53.93%), Query Frame = 3 Query: 99 LQENKDGNIFYSPLSISAAFCMLLLGTNDESSNQI---------IKALKYKKSKNEI-------HKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTSPT--AIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQRFELNSV--XXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISD-ENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDP 1181 L++ DGNIF+SP+ I A M+LLGT +++Q+ K+ + K + E+ H++ + L + + + N+Y +L+I N LF + + Y + ++K+Y + ++ ++F + + K++N W+ESKTN+KIKD+F +GS ++ T+LVL N VYFK + F+ ENT ++ F + T +V+MM S ++F L K+L IP+KN + + LP L + ++ ++ R+V+ L +P+F+++ +L+ ++ +G+ D F ++AD G+S L+ K +H +F+ V E G EAAAAT + S P +E+ + PFL + H +++I+F GR P Sbjct: 19 LKKTNDGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEKETKSSRIKAEEKEVIENTEAVHQQFQKFLTEISKLTNDY---ELNITNRLFGEKTYLFLQKYLDYVEKYYHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNMVYFKGQWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKNNDLSMFVLLPNDIDGLEKIIDKISPEKLVEWTSPGHMEERKVN-LHLPRFEVEDGYDLEAVLAAMGMGDAFSEHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSAPGHENVH-----CNHPFLFFIRHNESNSILFFGRFSSP 391
BLAST of SERPIN domain-containing protein vs. Ensembl Human
Match: SERPINI1 (serpin family I member 1 [Source:HGNC Symbol;Acc:HGNC:8943]) HSP 1 Score: 181.03 bits (458), Expect = 4.093e-52 Identity = 121/367 (32.97%), Postives = 208/367 (56.68%), Query Frame = 3 Query: 108 NKDGNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTSPTAIKE-VNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDS----QLG--LKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISD-ENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDPK 1184 +D NI +SPLSI+ A M+ LG + +I ++ Y KN +E S L + + ++ + Q + IAN LF+QN F + + + ++K++ + + ++F+ A+ +N W+E+ TN+ +KD+ F+ T L L NAVYFK N+K F ENT SF KD ++++ + MM G++ + E S + G +VLEIP++ ++ +L L Q L ++ +K ++ NS+K ++V +P+F ++ +++LKD++ LG+ +IF + A+L G+SD + +F+ KAIHK+FL+VNE G EAAA + M Y + IVD PF + ++ I+F+GRV P+ Sbjct: 41 GEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKN--GEEFSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQNVAVANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEVPLATLEPLVKAQLVEEWANSVKKQKVEVY-LPRFTVEQEIDLKDVLKALGITEIFIKD-ANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYP-----QVIVDHPFFFLIRNRRTGTILFMGRVMHPE 398
BLAST of SERPIN domain-containing protein vs. Ensembl Human
Match: SERPINI1 (serpin family I member 1 [Source:HGNC Symbol;Acc:HGNC:8943]) HSP 1 Score: 181.03 bits (458), Expect = 4.093e-52 Identity = 121/367 (32.97%), Postives = 208/367 (56.68%), Query Frame = 3 Query: 108 NKDGNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTSPTAIKE-VNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDS----QLG--LKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISD-ENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDPK 1184 +D NI +SPLSI+ A M+ LG + +I ++ Y KN +E S L + + ++ + Q + IAN LF+QN F + + + ++K++ + + ++F+ A+ +N W+E+ TN+ +KD+ F+ T L L NAVYFK N+K F ENT SF KD ++++ + MM G++ + E S + G +VLEIP++ ++ +L L Q L ++ +K ++ NS+K ++V +P+F ++ +++LKD++ LG+ +IF + A+L G+SD + +F+ KAIHK+FL+VNE G EAAA + M Y + IVD PF + ++ I+F+GRV P+ Sbjct: 41 GEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKN--GEEFSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQNVAVANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEVPLATLEPLVKAQLVEEWANSVKKQKVEVY-LPRFTVEQEIDLKDVLKALGITEIFIKD-ANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYP-----QVIVDHPFFFLIRNRRTGTILFMGRVMHPE 398
BLAST of SERPIN domain-containing protein vs. Ensembl Human
Match: SERPINB9 (serpin family B member 9 [Source:HGNC Symbol;Acc:HGNC:8955]) HSP 1 Score: 178.718 bits (452), Expect = 1.395e-51 Identity = 116/373 (31.10%), Postives = 196/373 (52.55%), Query Frame = 3 Query: 90 KTVLQENKDGNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINF--TSPTAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXX--SLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISDE-NLFVDKAIHKTFLDVNEHGIEAAAATAMSI---CCM-SMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDP 1181 K + Q+N N+F SP+SIS+A M+LLG ++ Q+ +AL ++ +IH+ LL + +Y L AN LF + + ++ +FY +E+K+++F + + K +N W+ KT KI+++ S + TRLVL NA+YFK + + F+ T + F + + + V+MM + A ++ ++LE+P+ ++ L+ LP EL++V L L +K +V L +PKFK+ +++ ++ LG+ D F +ADL +S E +L + K +HK+F++VNE G EAAAA++ + CCM S P F D PFL + H A++I+F GR P Sbjct: 17 KILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSLN-TEEDIHRAFQSLLTEVNKAGTQY---LLRTANRLFGEKTCQFLSTFKESCLQFYHAELKELSFIRAAEESRKHINTWVSKKTEGKIEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDETYTREMPFKINQEEQRPVQMMYQEATFKLAHVGEVRAQLLELPYARKELSLLVLLPDDGVELSTVEKSLTFEKLTAWTKPDCMKSTEVEVL-LPKFKLQEDYDMESVLRHLGIVDAFQQGKADLSAMSAERDLCLSKFVHKSFVEVNEEGTEAAAASSCFVVAECCMESGP--------RFCADHPFLFFIRHNRANSILFCGRFSSP 376
BLAST of SERPIN domain-containing protein vs. Ensembl Human
Match: SERPINB13 (serpin family B member 13 [Source:HGNC Symbol;Acc:HGNC:8944]) HSP 1 Score: 177.948 bits (450), Expect = 4.436e-51 Identity = 118/391 (30.18%), Postives = 207/391 (52.94%), Query Frame = 3 Query: 99 LQENKDGNIFYSPLSISAAFCMLLLGTNDESSNQI--------------IKA-----LKYKKSKNEI------HKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTSPT--AIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQRFELNSV--XXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISD-ENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDP 1181 L++ DGNIF+SP+ I A M+LLGT +++Q+ IKA ++ K EI H++ + L + + + N+Y +L+I N LF + + Y + ++K+Y + ++ ++F + + K++N W+ESKTN+KIKD+F +GS ++ T+LVL N VYFK + F+ ENT ++ F + T +V+MM S ++F L K+L IP+KN + + LP L + ++ ++ R+V+ L +P+F+++ +L+ ++ +G+ D F ++AD G+S L+ K +H +F+ V E G EAAAAT + S P +E+ + PFL + H +++I+F GR P Sbjct: 19 LKKTNDGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEKETKSSRIKAEEKEVVRIKAEGKEIENTEAVHQQFQKFLTEISKLTNDY---ELNITNRLFGEKTYLFLQKYLDYVEKYYHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNMVYFKGQWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKNNDLSMFVLLPNDIDGLEKIIDKISPEKLVEWTSPGHMEERKVN-LHLPRFEVEDGYDLEAVLAAMGMGDAFSEHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSAPGHENVH-----CNHPFLFFIRHNESNSILFFGRFSSP 400
BLAST of SERPIN domain-containing protein vs. Ensembl Celegans
Match: srp-7 (SeRPin; Serine or cysteine protease inhibitor [Source:UniProtKB/TrEMBL;Acc:Q6QUQ6]) HSP 1 Score: 146.362 bits (368), Expect = 9.115e-40 Identity = 102/341 (29.91%), Postives = 189/341 (55.43%), Query Frame = 3 Query: 102 QENKDGNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTSPTAIKE-VNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSG-DYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISDENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPF 1118 Q+N ++ +SPLSI+ A ++ + E+ +QI +AL + ++ + + + +A ++ T++ +AN +F + FKIK +Y ++++K Y + ++F + A E +N ++ T D IK + S N+ VL NA+YFK+++++ F+ ++T F +K + + S ++AE+ Q +VL +P+K+ +FLP RF L L L +++L++++ V+ +++PK+KI+T+L L++ + LG++ FD N ADL ++D L+V K HK ++V+E G +AAAAT +SI S F E +F D PF Sbjct: 25 QQNISESLAFSPLSIALALSLVHVAAKGETRDQIREALVKGSTDEQLEQHFANI---SAALLAAERGTEVKLANHVFTRAGFKIKQSYLDDVKKLYNAGASSLDFDNKEATAEAINNFVRENTGDHIKKIIGSDSINSDLVAVLTNALYFKADWQNKFKKDSTFKSEFFSSADSKREIDFLHASSVSRDYAENDQ--FQVLSLPYKDNTFALTIFLPKTRFGLTESLKTLDSATIQHLLSNVSSTSVN-VQIPKWKIETKLGLEEALQSLGIKKAFD-NDADLGNMAD-GLYVSKVTHKALIEVDEEGTKAAAATTVSISLKSAMFV-MEEPKDFTADHPF 356
BLAST of SERPIN domain-containing protein vs. Ensembl Celegans
Match: srp-7 (SeRPin; Serine or cysteine protease inhibitor [Source:UniProtKB/TrEMBL;Acc:Q6QUQ6]) HSP 1 Score: 145.976 bits (367), Expect = 1.042e-39 Identity = 102/341 (29.91%), Postives = 189/341 (55.43%), Query Frame = 3 Query: 102 QENKDGNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTSPTAIKE-VNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSG-DYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISDENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPF 1118 Q+N ++ +SPLSI+ A ++ + E+ +QI +AL + ++ + + + +A ++ T++ +AN +F + FKIK +Y ++++K Y + ++F + A E +N ++ T D IK + S N+ VL NA+YFK+++++ F+ ++T F +K + + S ++AE+ Q +VL +P+K+ +FLP RF L L L +++L++++ V+ +++PK+KI+T+L L++ + LG++ FD N ADL ++D L+V K HK ++V+E G +AAAAT +SI S F E +F D PF Sbjct: 18 QQNISESLAFSPLSIALALSLVHVAAKGETRDQIREALVKGSTDEQLEQHFANI---SAALLAAERGTEVKLANHVFTRAGFKIKQSYLDDVKKLYNAGASSLDFDNKEATAEAINNFVRENTGDHIKKIIGSDSINSDLVAVLTNALYFKADWQNKFKKDSTFKSEFFSSADSKREIDFLHASSVSRDYAENDQ--FQVLSLPYKDNTFALTIFLPKTRFGLTESLKTLDSATIQHLLSNVSSTSVN-VQIPKWKIETKLGLEEALQSLGIKKAFD-NDADLGNMAD-GLYVSKVTHKALIEVDEEGTKAAAATTVSISLKSAMFV-MEEPKDFTADHPF 349
BLAST of SERPIN domain-containing protein vs. Ensembl Celegans
Match: srp-7 (SeRPin; Serine or cysteine protease inhibitor [Source:UniProtKB/TrEMBL;Acc:Q6QUQ6]) HSP 1 Score: 144.05 bits (362), Expect = 4.105e-39 Identity = 104/359 (28.97%), Postives = 196/359 (54.60%), Query Frame = 3 Query: 102 QENKDGNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTSPTAIKE-VNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSG-DYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISDENLFVDKAIHKTFLDVNEHGIEAAAATAMSI--CCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIG 1166 Q+N ++ +SPLSI+ A ++ + E+ +QI +AL + ++ + + + +A ++ T++ +AN +F + FKIK +Y ++++K Y + ++F + A E +N ++ T D IK + S N+ VL NA+YFK+++++ F+ ++T F +K + + S ++AE+ Q +VL +P+K+ +FLP RF L L L +++L++++ V+ +++PK+KI+T+L L++ + LG++ FD N ADL ++D L+V K HK ++V+E G A AAT SI C M E +EF + PF ++H + + +F+G Sbjct: 18 QQNISESLAFSPLSIALALSLVHVAAKGETRDQIREALVKGSTDEQLEQHFANI---SAALLAAERGTEVKLANHVFTRAGFKIKQSYLDDVKKLYNAGASSLDFDNKEATAEAINNFVRENTGDHIKKIIGSDSINSDLVAVLTNALYFKADWQNKFKKDSTFKSEFFSSADSKREIDFLHASSVSRDYAENDQ--FQVLSLPYKDNTFALTIFLPKTRFGLTESLKTLDSATIQHLLSNVSSTSVN-VQIPKWKIETKLGLEEALQSLGIKKAFD-NDADLGNMAD-GLYVSKVTHKALIEVDEDGTVAVAATRCSIERCRKKMK-----ENIEFHAEHPFFFILHHGT--SYIFLG 361
BLAST of SERPIN domain-containing protein vs. Ensembl Celegans
Match: srp-7 (SeRPin; Serine or cysteine protease inhibitor [Source:UniProtKB/TrEMBL;Acc:Q6QUQ6]) HSP 1 Score: 139.428 bits (350), Expect = 2.556e-37 Identity = 101/343 (29.45%), Postives = 189/343 (55.10%), Query Frame = 3 Query: 102 QENKDGNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTSPTAIKE-VNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSG-DYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISDENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSM-PFYESNETLEFIVDEPFL 1121 Q+N ++ +SPLSI+ A ++ + E+ +QI +AL + ++ + + + +A ++ T++ +AN +F + FKIK +Y ++++K Y + ++F + A E +N ++ T D IK + S N+ VL NA+YFK+++++ F+ ++T F +K + + S ++AE+ Q +VL +P+K+ +FLP RF L L L +++L++++ V+ +++PK+KI+T+L L++ + LG++ FD N ADL ++D L+V K HK ++V+E G AAAAT +S S P + + + F D PFL Sbjct: 18 QQNISESLAFSPLSIALALSLVHVAAKGETRDQIREALVKGSTDEQLEQHFANI---SAALLAAERGTEVKLANHVFTRAGFKIKQSYLDDVKKLYNAGASSLDFDNKEATAEAINNFVRENTGDHIKKIIGSDSINSDLVAVLTNALYFKADWQNKFKKDSTFKSEFFSSADSKREIDFLHASSVSRDYAENDQ--FQVLSLPYKDNTFALTIFLPKTRFGLTESLKTLDSATIQHLLSNVSSTSVN-VQIPKWKIETKLGLEEALQSLGIKKAFD-NDADLGNMAD-GLYVSKVTHKALIEVDEEGTTAAAATVVSFVRKSARP--SAIKPIVFQADHPFL 350
BLAST of SERPIN domain-containing protein vs. Ensembl Celegans
Match: srp-2 (SeRPin [Source:UniProtKB/TrEMBL;Acc:O17365]) HSP 1 Score: 134.42 bits (337), Expect = 1.725e-35 Identity = 102/340 (30.00%), Postives = 182/340 (53.53%), Query Frame = 3 Query: 117 GNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFT-SPTAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDY-NFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISDENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSV 1130 G++ SPLSIS ++ G + ++ L + I +E S L++ + + + + I N +F+ + I +Y ++K YK+ + ++F+ + A K +N ++E+ TN KIKD+ S NN L NA+YFK++++ F E+T + F + + ++ ++ ED + +VL + + + + +FLP QRF L L K+ ++NL+N LK VS +++PKFKI+ +L+LK+ + +G+++IF ADL GI+D+ +F+ IHK ++V+E G AAAA+A + M E +F+ D PFL +V Sbjct: 23 GSVVLSPLSISLGLALIHAGACGSTQKELEDVL----GGSRIFEEFSGLME---AVGDTDNGVETKIVNRVFVNQAYTIHQDYLETVEKLYKASGESLDFSQTEQAAKTMNTFVENHTNGKIKDLIPADSANNAFAF-LVNAMYFKADWQSKFAKESTTGREFFTSEAESRQIPFLTELDEHRDYTED--VLFQVLSLKYADPKFTLAIFLPKQRFGLVDALEKINGEYIQNLLNDLKSSYVS-VQIPKFKIEKELDLKETLEAIGIKEIF-AEGADLSGIADK-VFISSGIHKAIIEVDEDGTTAAAASAFKVQLEMMIMAEPT---QFVADHPFLFAV 346
BLAST of SERPIN domain-containing protein vs. Ensembl Fly
Match: Spn55B (gene:FBgn0028983 transcript:FBtr0086733) HSP 1 Score: 153.68 bits (387), Expect = 2.048e-42 Identity = 107/353 (30.31%), Postives = 188/353 (53.26%), Query Frame = 3 Query: 120 NIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQL-SIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFT-SPTAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGI--SDENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIG 1166 N+ +SP SI + G+ E++++I KAL + + E+ ++ +Y + L +AN L++Q ++K YQ+ +++ Y SE + INF + A + +N W+ +KT KI ++ SF++ TRLVL NA++FK ++ F E T + F + ++ + M +N+ LG LE+P+++ + + LP +R + ++ KLK +L +L + L + +V ++ PKFK+D L L + + LG+ +F ++A+ + S E +FV K +HK ++VNE G EAAAAT M + M F L+F D PFL +++K I+F G Sbjct: 31 NVVFSPFSIQTCIALAFAGSQGETADEIAKALHF------VSNFPPEVAQTFQFVLEKYRNSNLLRVANKLYVQEGKQLKPAYQSAIKEQYHSEAESINFALNDAAAQAINAWVNAKTQGKITELVSADSFSDNTRLVLLNALHFKGSWAHKFSEERTEEDIFWVGEEEQVKINYMNQKAKFNYGFFEDLGCTALEMPYQDSDLSMFVLLPQERTGIYALAEKLKTVNLVDLADKLTVEEVH-VKFPKFKVDYSLELAEKLKQLGITKMFT-DQAEFSNLLESPEGVFVSKVLHKATIEVNEEGTEAAAATGMIMMTRMMTF-----PLQFQADRPFLYVIWNKK--NILFAG 368
BLAST of SERPIN domain-containing protein vs. Ensembl Fly
Match: Spn42Da (gene:FBgn0265137 transcript:FBtr0300336) HSP 1 Score: 150.599 bits (379), Expect = 3.462e-41 Identity = 113/364 (31.04%), Postives = 193/364 (53.02%), Query Frame = 3 Query: 99 LQENKDG-NIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQ-LSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFT-SPTAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGI--SDENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVD 1175 L K G NI +SP SI M LG +E++ Q+ + L S E +I+ + ++ Y +Q L IAN +F+ + ++++ + L K + S + ++F+ + A +N W+E +TN IKD+ N+ +RLVL NA++FK ++ F T +FH D + + V MM + +A+ L LE+P+K+ + L+ LP + L ++ KL+ L + SL +V+ L++P+FK + Q+ L ++ LG+ +F ++A+ + S E L V IHK F++VNE G EAAAAT M +C SM +E + ++F V PF + +K + I+F GR++ Sbjct: 24 LSGQKPGENIVFSPFSIQTCAAMARLGAENETATQLDQGLGLASSDPE---QIAHSFHQ---VLAAYQDSQILRIANKIFVMDGYQLRQEFDQLLSKQFLSAAQSVDFSKNVQAAATINNWVEQRTNHLIKDLVPADVLNSESRLVLVNAIHFKGTWQHQFAKHLTRPDTFHLDGERTVQVPMMSLKERFRYADLPALDAMALELPYKDSDLSMLIVLPNTKTGLPALEEKLRLTTLSQITQSLYETKVA-LKLPRFKAEFQVELSEVFQKLGMSRMFS-DQAEFGKMLQSPEPLKVSAIIHKAFIEVNEEGTEAAAATGMVMCYASMLTFEP-QPVQFHVQHPFNYYIINKDS-TILFAGRIN 377
BLAST of SERPIN domain-containing protein vs. Ensembl Fly
Match: Spn42Da (gene:FBgn0265137 transcript:FBtr0086205) HSP 1 Score: 150.599 bits (379), Expect = 3.462e-41 Identity = 113/364 (31.04%), Postives = 193/364 (53.02%), Query Frame = 3 Query: 99 LQENKDG-NIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQ-LSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFT-SPTAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGI--SDENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVD 1175 L K G NI +SP SI M LG +E++ Q+ + L S E +I+ + ++ Y +Q L IAN +F+ + ++++ + L K + S + ++F+ + A +N W+E +TN IKD+ N+ +RLVL NA++FK ++ F T +FH D + + V MM + +A+ L LE+P+K+ + L+ LP + L ++ KL+ L + SL +V+ L++P+FK + Q+ L ++ LG+ +F ++A+ + S E L V IHK F++VNE G EAAAAT M +C SM +E + ++F V PF + +K + I+F GR++ Sbjct: 24 LSGQKPGENIVFSPFSIQTCAAMARLGAENETATQLDQGLGLASSDPE---QIAHSFHQ---VLAAYQDSQILRIANKIFVMDGYQLRQEFDQLLSKQFLSAAQSVDFSKNVQAAATINNWVEQRTNHLIKDLVPADVLNSESRLVLVNAIHFKGTWQHQFAKHLTRPDTFHLDGERTVQVPMMSLKERFRYADLPALDAMALELPYKDSDLSMLIVLPNTKTGLPALEEKLRLTTLSQITQSLYETKVA-LKLPRFKAEFQVELSEVFQKLGMSRMFS-DQAEFGKMLQSPEPLKVSAIIHKAFIEVNEEGTEAAAATGMVMCYASMLTFEP-QPVQFHVQHPFNYYIINKDS-TILFAGRIN 377
BLAST of SERPIN domain-containing protein vs. Ensembl Fly
Match: Spn42Da (gene:FBgn0265137 transcript:FBtr0086202) HSP 1 Score: 150.599 bits (379), Expect = 3.462e-41 Identity = 113/364 (31.04%), Postives = 193/364 (53.02%), Query Frame = 3 Query: 99 LQENKDG-NIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQ-LSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFT-SPTAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGI--SDENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVD 1175 L K G NI +SP SI M LG +E++ Q+ + L S E +I+ + ++ Y +Q L IAN +F+ + ++++ + L K + S + ++F+ + A +N W+E +TN IKD+ N+ +RLVL NA++FK ++ F T +FH D + + V MM + +A+ L LE+P+K+ + L+ LP + L ++ KL+ L + SL +V+ L++P+FK + Q+ L ++ LG+ +F ++A+ + S E L V IHK F++VNE G EAAAAT M +C SM +E + ++F V PF + +K + I+F GR++ Sbjct: 24 LSGQKPGENIVFSPFSIQTCAAMARLGAENETATQLDQGLGLASSDPE---QIAHSFHQ---VLAAYQDSQILRIANKIFVMDGYQLRQEFDQLLSKQFLSAAQSVDFSKNVQAAATINNWVEQRTNHLIKDLVPADVLNSESRLVLVNAIHFKGTWQHQFAKHLTRPDTFHLDGERTVQVPMMSLKERFRYADLPALDAMALELPYKDSDLSMLIVLPNTKTGLPALEEKLRLTTLSQITQSLYETKVA-LKLPRFKAEFQVELSEVFQKLGMSRMFS-DQAEFGKMLQSPEPLKVSAIIHKAFIEVNEEGTEAAAATGMVMCYASMLTFEP-QPVQFHVQHPFNYYIINKDS-TILFAGRIN 377
BLAST of SERPIN domain-containing protein vs. Ensembl Fly
Match: Spn42Da (gene:FBgn0265137 transcript:FBtr0086200) HSP 1 Score: 150.599 bits (379), Expect = 6.618e-41 Identity = 113/364 (31.04%), Postives = 193/364 (53.02%), Query Frame = 3 Query: 99 LQENKDG-NIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQ-LSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFT-SPTAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGI--SDENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVD 1175 L K G NI +SP SI M LG +E++ Q+ + L S E +I+ + ++ Y +Q L IAN +F+ + ++++ + L K + S + ++F+ + A +N W+E +TN IKD+ N+ +RLVL NA++FK ++ F T +FH D + + V MM + +A+ L LE+P+K+ + L+ LP + L ++ KL+ L + SL +V+ L++P+FK + Q+ L ++ LG+ +F ++A+ + S E L V IHK F++VNE G EAAAAT M +C SM +E + ++F V PF + +K + I+F GR++ Sbjct: 56 LSGQKPGENIVFSPFSIQTCAAMARLGAENETATQLDQGLGLASSDPE---QIAHSFHQ---VLAAYQDSQILRIANKIFVMDGYQLRQEFDQLLSKQFLSAAQSVDFSKNVQAAATINNWVEQRTNHLIKDLVPADVLNSESRLVLVNAIHFKGTWQHQFAKHLTRPDTFHLDGERTVQVPMMSLKERFRYADLPALDAMALELPYKDSDLSMLIVLPNTKTGLPALEEKLRLTTLSQITQSLYETKVA-LKLPRFKAEFQVELSEVFQKLGMSRMFS-DQAEFGKMLQSPEPLKVSAIIHKAFIEVNEEGTEAAAATGMVMCYASMLTFEP-QPVQFHVQHPFNYYIINKDS-TILFAGRIN 409
BLAST of SERPIN domain-containing protein vs. Ensembl Zebrafish
Match: serpinb1l3 (serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 3 [Source:ZFIN;Acc:ZDB-GENE-030131-7059]) HSP 1 Score: 172.555 bits (436), Expect = 2.329e-49 Identity = 115/379 (30.34%), Postives = 205/379 (54.09%), Query Frame = 3 Query: 93 TVLQENKDG----NIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQ-LSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTS-PTAIKEV-NGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLP-TQRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEV----PKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGI-SDENLFVDKAIHKTFLDVN---EHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDP 1181 ++ Q+ DG N+F+SPLSISAA ML LG + +Q+ + L + ++++IH ++LL + MN LS+A+ L+ + + + ++ + ++ ++ Y +E++ ++F S P A + + N W+E +T++KI+D+ EGS ++L+RLVL NAVYFKS+++ F E+T ++ F V+MM G + A + ++LE+P+ ++ L+ LP + + + L+ L + + + LEV P+ +++ +L LK L+ LG+ D FDP RAD G+ + L + +H++FL+VN A AA M+ C M F D PFL+ + H +++F GRV +P Sbjct: 14 SLFQKISDGDSSQNVFFSPLSISAALSMLSLGAAGNTKDQMSQTLHFDGAESQIHAGFTKLLTE----MNRAGAPHTLSLASRLYGEQSCRFQETFLSDTRRLYGAELQPLDFISQPEASRGIINRWVEQQTHEKIRDLLAEGSVDSLSRLVLVNAVYFKSSWERKFLEEHTHEQQFRTSRNESKPVQMMFQKGRFPLAFIPDVNCQILELPYAGKELSMLVLLPNAMEDDGTGLEKLERALTLETLTDWTRSDMMDVLEVEVSLPRLRVEERLELKPLLVELGMPDAFDPQRADFSGVCAGGELLLSTVVHQSFLEVNEEGTEAAAATAAVMMTRCLM--------RAERFCADHPFLMLIRHNPTGSLLFYGRVCNP 380
BLAST of SERPIN domain-containing protein vs. Ensembl Zebrafish
Match: serpinb1l1 (serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 1 [Source:ZFIN;Acc:ZDB-GENE-040715-5]) HSP 1 Score: 169.474 bits (428), Expect = 4.189e-48 Identity = 112/379 (29.55%), Postives = 195/379 (51.45%), Query Frame = 3 Query: 90 KTVLQENKDGNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQ----LSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFT--SPTAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLP------TQRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISDEN-LFVDKAIHKTFLDVN--EHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDP 1181 K + N GN+FYSP+SIS+A M+ LG +++Q+ K L + ++ H+ + ++ M+E ++ + LS+AN L+ + +++ + + N+ +++Y + ++K++F S A +N W+E T +KIKD+ G+ + +TRLVL NA+YFK N+++ F E T D F + VKMM ++ ++ VLE+P+ + L+ LP T + ++ + R+V + +PKFK + ++K L+ +G++D+FDP + +L G+S N L + KAIHK F++VN AA A + C P L F D PFL + H +I+F GR+ P Sbjct: 17 KKISGGNASGNVFYSPVSISSALAMVSLGAKGNTADQMFKVLGFN---SQAHQPVEQIHSNFKKFMSELNKPEAPYVLSLANRLYGEQTYQLIEKFLNDTKRYYDAGLEKVDFINKSEDARVNINTWVEKNTQEKIKDLLPSGAIDAMTRLVLVNAIYFKGNWEEKFPKEATRDGVFRLNKNQTKPVKMMHQKAEFPSGYIEEMKSHVLELPYAGKNLSMLIILPDEIEDETTGLQKLERALTYEKLMEWTKPEVMHQREVQ-VSLPKFKTEQTYDMKSLLVSMGMEDVFDPQKVNLTGMSSSNDLVLSKAIHKAFVEVNEEGTEAAAATAAIEKLMCYIPP-------LSFNADHPFLFFIRHNPTKSILFYGRLCSP 384
BLAST of SERPIN domain-containing protein vs. Ensembl Zebrafish
Match: serpinb1l1 (serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 1 [Source:ZFIN;Acc:ZDB-GENE-040715-5]) HSP 1 Score: 169.474 bits (428), Expect = 4.189e-48 Identity = 112/379 (29.55%), Postives = 195/379 (51.45%), Query Frame = 3 Query: 90 KTVLQENKDGNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQ----LSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFT--SPTAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLP------TQRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISDEN-LFVDKAIHKTFLDVN--EHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDP 1181 K + N GN+FYSP+SIS+A M+ LG +++Q+ K L + ++ H+ + ++ M+E ++ + LS+AN L+ + +++ + + N+ +++Y + ++K++F S A +N W+E T +KIKD+ G+ + +TRLVL NA+YFK N+++ F E T D F + VKMM ++ ++ VLE+P+ + L+ LP T + ++ + R+V + +PKFK + ++K L+ +G++D+FDP + +L G+S N L + KAIHK F++VN AA A + C P L F D PFL + H +I+F GR+ P Sbjct: 17 KKISGGNASGNVFYSPVSISSALAMVSLGAKGNTADQMFKVLGFN---SQAHQPVEQIHSNFKKFMSELNKPEAPYVLSLANRLYGEQTYQLIEKFLNDTKRYYDAGLEKVDFINKSEDARVNINTWVEKNTQEKIKDLLPSGAIDAMTRLVLVNAIYFKGNWEEKFPKEATRDGVFRLNKNQTKPVKMMHQKAEFPSGYIEEMKSHVLELPYAGKNLSMLIILPDEIEDETTGLQKLERALTYEKLMEWTKPEVMHQREVQ-VSLPKFKTEQTYDMKSLLVSMGMEDVFDPQKVNLTGMSSSNDLVLSKAIHKAFVEVNEEGTEAAAATAAIEKLMCYIPP-------LSFNADHPFLFFIRHNPTKSILFYGRLCSP 384
BLAST of SERPIN domain-containing protein vs. Ensembl Zebrafish
Match: serpinc1 (serpin peptidase inhibitor, clade C (antithrombin), member 1 [Source:ZFIN;Acc:ZDB-GENE-030131-264]) HSP 1 Score: 169.859 bits (429), Expect = 1.118e-47 Identity = 115/366 (31.42%), Postives = 203/366 (55.46%), Query Frame = 3 Query: 114 DGNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKY----KKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTS-PTAIK-EVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGI----SDENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDP 1181 D NIF SP+SIS AF M LG + + Q++K ++ +K+ +++H ++L + +++ T+L AN LF + + +Q+ + Y +++ ++F P A + +N WI +KT ++IKD EGS + T LVL NA+YFK +K+ F+ +N + FH K V MM + +A+ + +K+LE+P+ + +L LP + L+ V+ + L ++++K V+ +++P+F+++ +LK+ + +G++D+F P A L G+ NLF+ A HK FL+VNE G EA+AATA+ S+ + +F+ D PFLL + S +A++F GRV +P Sbjct: 88 DENIFLSPISISTAFAMTKLGACNTTLEQLMKVFQFDTIKEKTSDQVHFFFAKL--NCRLYRKKHETTELISANRLFGDKSTTFNETFQHISETVYGAKLMPLDFKEKPEASRITINEWIANKTENRIKDTLPEGSIDTNTILVLVNAIYFKGQWKNKFDKQNVMKLDFHVSPTHKCPVPMMYQEKKFQYAKIPEDKVKILELPYNGGDITMVLILPIEGATLSEVVANMNLKKLVGWLHAMKETTVA-VQIPRFRVEDSFSLKEQLTKMGLEDLFSPANASLPGMVADAEGPNLFISDAYHKAFLEVNEEGSEASAATAVVATGRSLNIFRE----QFVADRPFLLFIRESSINALIFTGRVANP 446
BLAST of SERPIN domain-containing protein vs. Ensembl Zebrafish
Match: serpinc1 (serpin peptidase inhibitor, clade C (antithrombin), member 1 [Source:ZFIN;Acc:ZDB-GENE-030131-264]) HSP 1 Score: 169.859 bits (429), Expect = 1.118e-47 Identity = 115/366 (31.42%), Postives = 203/366 (55.46%), Query Frame = 3 Query: 114 DGNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKY----KKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTS-PTAIK-EVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGI----SDENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDP 1181 D NIF SP+SIS AF M LG + + Q++K ++ +K+ +++H ++L + +++ T+L AN LF + + +Q+ + Y +++ ++F P A + +N WI +KT ++IKD EGS + T LVL NA+YFK +K+ F+ +N + FH K V MM + +A+ + +K+LE+P+ + +L LP + L+ V+ + L ++++K V+ +++P+F+++ +LK+ + +G++D+F P A L G+ NLF+ A HK FL+VNE G EA+AATA+ S+ + +F+ D PFLL + S +A++F GRV +P Sbjct: 88 DENIFLSPISISTAFAMTKLGACNTTLEQLMKVFQFDTIKEKTSDQVHFFFAKL--NCRLYRKKHETTELISANRLFGDKSTTFNETFQHISETVYGAKLMPLDFKEKPEASRITINEWIANKTENRIKDTLPEGSIDTNTILVLVNAIYFKGQWKNKFDKQNVMKLDFHVSPTHKCPVPMMYQEKKFQYAKIPEDKVKILELPYNGGDITMVLILPIEGATLSEVVANMNLKKLVGWLHAMKETTVA-VQIPRFRVEDSFSLKEQLTKMGLEDLFSPANASLPGMVADAEGPNLFISDAYHKAFLEVNEEGSEASAATAVVATGRSLNIFRE----QFVADRPFLLFIRESSINALIFTGRVANP 446
BLAST of SERPIN domain-containing protein vs. Ensembl Xenopus
Match: serpini1 (serpin family I member 1 [Source:NCBI gene;Acc:100144746]) HSP 1 Score: 199.134 bits (505), Expect = 5.593e-59 Identity = 130/366 (35.52%), Postives = 213/366 (58.20%), Query Frame = 3 Query: 111 KDGNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFT-SPTAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAE----DSQLG--LKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISD-ENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDPK 1184 +D NI +SPLS + A M+ LG S +I L Y K KN +E S L D + ++ + LSIAN L++QN F I D + ++K++K+E++ ++F+ T +N W+E+ TN++I+D+ F NLT+LVL NA+YFK N+K F ENT SF KD ++++ + MM G++ + E ++ G +VLE+P++ ++ ++ L Q L ++ LK ++ NS+K ++V +P+FK++ +NLKD++ LG+ IF ADL +SD ++LFV KA+HK+FL+VNE G EAAA++ M Y + IVD PF + ++ +++F+GRV P+ Sbjct: 42 EDENIIFSPLSTAIALGMVELGARGSSLKEIRHVLGYDKLKNG--EEFSLLKDLSNMLTAQEKHYVLSIANSLYLQNGFHISDKFIQLMKKYFKAEVENVDFSQGSTVANHINMWVENHTNNRIRDLVTADDFTNLTKLVLVNAMYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQKGEFYYGEFTDGSNEAGGVYQVLELPYEGDEISLIIVLSRQEVPLATLEPLLKAPLIEEWANSVKKQKVEVY-LPRFKVEEVVNLKDVLMQLGITKIFS-GEADLSAVSDSKDLFVAKAVHKSFLEVNEEGSEAAASSGMIANSRMAVLYP-----QVIVDHPFFFVIRNRKTGSVLFMGRVMHPE 398
BLAST of SERPIN domain-containing protein vs. Ensembl Xenopus
Match: marveld3 (MARVEL domain containing 3 [Source:Xenbase;Acc:XB-GENE-5929351]) HSP 1 Score: 175.252 bits (443), Expect = 6.930e-50 Identity = 113/358 (31.56%), Postives = 189/358 (52.79%), Query Frame = 3 Query: 120 NIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTSPTAIKE-VNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXX--XXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISDE-NLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDP 1181 NI +SPL S M+ LG + +QI +ALK + N+ +E SEL AVI E + ++AN L++Q F++K+ Y + + + S +K ++F A E ++ W++ +T+ KI MF G F LT++VL NA+YFK +K F +E T + F + + ++T+ + KVLE+P+K + LL LP + E+ + + +K +K +V + +P+FK++ +++LK L + DIF+ DL GI++ NL++ K K FL++NE G EAAA+T M + MSM + F + PFL + H + I+F+G+V +P Sbjct: 50 NIIFSPLGTSLILGMIKLGARGAALSQIQQALKLQG--NQDSEEFSELKTLLAVISEENKEFTFNLANALYLQEGFQVKEQYLHSNRDVFNSAIKLVDFQDVKASAETISEWVQRQTHGKISKMFSSGDFTPLTKMVLVNALYFKGEWKQKFSVEATHSEEFSVKRGLTVKVPMMHLQTTTKLGYFSVKNASYKVLELPYKGDKFSLLLTLPAEDVEIGELEKIVTATMIKTWFADMK-EEVVEISLPRFKVEHKIDLKKSFLNLNITDIFNEG-CDLSGITESPNLYISKVFQKVFLEINEEGSEAAASTGMQVSAMSMSSH------RFAANRPFLFFIRHIQSGMILFMGKVMNP 397
BLAST of SERPIN domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000024938.1 (serpin peptidase inhibitor, clade B (ovalbumin), member 4 [Source:NCBI gene;Acc:100490314]) HSP 1 Score: 170.629 bits (431), Expect = 2.041e-48 Identity = 116/373 (31.10%), Postives = 202/373 (54.16%), Query Frame = 3 Query: 120 NIFYSPLSISAAFCMLLLGTNDESSNQIIKALKY------KKSKNEIHKEISE-----LL--DKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTSPT--AIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPF-KNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVS-TLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISDE-NLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDPK 1184 NI +SPLSI +A ++LLG+ +++ +I K + + SK ++ + LL D + + D +LSIAN + + +F + Y +++ Y + ++ ++F + I+++N W+ESKT KI+++F +GS ++ T L L NAVYFK ++K F+ ENT D F + K +VKMM G Y + +L ++L++P+ + + M+ + LP L + L L++ + R+V +++P+FK +L +++ +G+ F + A+L GISD+ L + +HK++++VNE G EAAAAT + I S P EFIVD PFL + H S +++F GR P+ Sbjct: 27 NILFSPLSICSAMGLVLLGSKGDTAAEIEKVFHFPAAAGSRSSKPSCQQQTCQAQGVHLLFKDLFSALNKPNDHYELSIANRAYGEKSFPFSEQYLLCIEQLYNATLESVDFKTKADDVIQQINAWVESKTKGKIQNLFAKGSLDSTTALALVNAVYFKGSWKKQFKKENTTDAPFFLNKNDKTSVKMMSQKGKYKLGSNPELKCRILKLPYEEGFSMK--IILPDDIDGLAELETHLTYETFTKLMDLQRTREVQVVVKLPQFKFGETYSLTEVLQSMGMTSAF--HGANLSGISDKAGLAISTVVHKSYIEVNEEGTEAAAATGIGITVTSAPLPPQ----EFIVDRPFLFCIEHISTKSLLFYGRFTFPE 391
BLAST of SERPIN domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000024879.1 (serpin peptidase inhibitor, clade B (ovalbumin), member 4 [Source:NCBI gene;Acc:100490314]) HSP 1 Score: 168.318 bits (425), Expect = 1.422e-47 Identity = 114/369 (30.89%), Postives = 198/369 (53.66%), Query Frame = 3 Query: 120 NIFYSPLSISAAFCMLLLGTNDESSNQIIKALK--------YKKSKNEIHKEISELLDKTAVIMNEY-DQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTSPT--AIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPF-KNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVS-TLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISDE-NLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDPK 1184 NI +SPLSI +A ++LLG+ +++ +I K K + KS + + + L +N+ D +LSIAN + + +F + Y +++ Y + ++ ++F + I+++N W+ESKT KI+++F +GS ++ T L L NAVYFK ++K F+ ENT D F +KMM G Y + +L ++L++P+ + + M+ + LP L + L L++ + R+V +++P+FK +L +++ +G+ F + A+L GISD+ L + +HK++++VNE G EAAAAT + I S P EFIVD PFL + H S +++F GR P+ Sbjct: 27 NILFSPLSICSAMGLVLLGSKGDTAAEIEKVRKIYCTIRGNFGKSPKKTSQGVHLLFKDLFSALNKPNDHYELSIANRAYGEKSFPFSEQYLLCIEQLYNATLESVDFKTKADDVIQQINAWVESKTKGKIQNLFAKGSLDSTTALALVNAVYFKGSWKKQFKKENTTDAPFF----LNKVLKMMSQKGKYKLGSNPELKCRILKLPYEEGFSMK--IILPDDIDGLAELETHLTYETFTKLMDLQRTREVQVVVKLPQFKFGETYSLTEVLQSMGMTSAF--HGANLSGISDKAGLAISTVVHKSYIEVNEEGTEAAAATGIGITVTSAPLPPQ----EFIVDRPFLFCIEHISTKSLLFYGRFTFPE 383
BLAST of SERPIN domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000037442.1 (serpin peptidase inhibitor, clade B (ovalbumin), member 4 [Source:NCBI gene;Acc:100490314]) HSP 1 Score: 165.622 bits (418), Expect = 1.139e-46 Identity = 112/360 (31.11%), Postives = 193/360 (53.61%), Query Frame = 3 Query: 120 NIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTSPT--AIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPF-KNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVS-TLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISDE-NLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDPK 1184 NI +SPLSI +A ++LLG+ +++ +I K +K I I+ L + D +LSIAN + + +F + Y +++ Y + ++ ++F + I+++N W+ESKT KI+++F +GS ++ T L L NAVYFK ++K F+ ENT D +KMM G Y + +L ++L++P+ + + M+ + LP L + L L++ + R+V +++P+FK +L +++ +G+ F + A+L GISD+ L + +HK++++VNE G EAAAAT + I S P EFIVD PFL + H S +++F GR P+ Sbjct: 27 NILFSPLSICSAMGLVLLGSKGDTAAEIEKV---RKIYCTIVSNITCSLLWKRTLNKPNDHYELSIANRAYGEKSFPFSEQYLLCIEQLYNATLESVDFKTKADDVIQQINAWVESKTKGKIQNLFAKGSLDSTTALALVNAVYFKGSWKKQFKKENTTDSCI---PFENSLLKMMSQKGKYKLGSNPELKCRILKLPYEEGFSMK--IILPDDIDGLAELETHLTYETFTKLMDLQRTREVQVVVKLPQFKFGETYSLTEVLQSMGMTSAF--HGANLSGISDKAGLAISTVVHKSYIEVNEEGTEAAAATGIGITVTSAPLPPQ----EFIVDRPFLFCIEHISTKSLLFYGRFTFPE 372
BLAST of SERPIN domain-containing protein vs. Ensembl Mouse
Match: Serpinb3a (serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A [Source:MGI Symbol;Acc:MGI:3573933]) HSP 1 Score: 186.037 bits (471), Expect = 2.043e-54 Identity = 115/373 (30.83%), Postives = 201/373 (53.89%), Query Frame = 3 Query: 114 DGNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNE-------------IHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINF--TSPTAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVST-LEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISD-ENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDP 1181 D NIFYSP+S+ A ML LG + QI K L++ ++ + +H++ +L+ + + YD L AN ++ F + +++++Y++ ++ ++F + + K++N W+ES+TN KIKD+F GS N T +VL NAVYFK + F+ ++T ++ F + T V+MMK + ++NF + K++EIP+K ++ ++ LP + L + +L + L + + L +P+FK+D + +L + +G+ D FDP +AD G+S + L V K +HK+F++VNE G EAAAAT + + S E +F D PFL + H+ ++I+F GR+ P Sbjct: 23 DNNIFYSPISMMTALAMLQLGAKGNTEKQIEKVLQFNETTKKTTEKSAHCHDEENVHEQFQKLMTQLNKSNDAYD---LKAANSIYGAKGFPFVQTFLEDIKEYYQANVESLDFEHAAEESEKKINSWVESQTNGKIKDLFPNGSLNRSTIMVLVNAVYFKGQWNHKFDEKHTTEEKFWLNKNTSKPVQMMKQNIEFNFMFLEDVQAKIVEIPYKGKELSMIVLLPVEINGLKQLEEQLTADKLLEWTRAENMHMTELYLSLPRFKVDEKYDLPIPLEHMGMVDAFDPQKADFSGMSSTQGLVVSKVLHKSFVEVNEEGTEAAAATGVEVSLTSAQIAE-----DFCCDHPFLFFIIHRKTNSILFFGRISSP 387
BLAST of SERPIN domain-containing protein vs. Ensembl Mouse
Match: Serpinb3a (serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A [Source:MGI Symbol;Acc:MGI:3573933]) HSP 1 Score: 186.037 bits (471), Expect = 2.043e-54 Identity = 115/373 (30.83%), Postives = 201/373 (53.89%), Query Frame = 3 Query: 114 DGNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNE-------------IHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINF--TSPTAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVST-LEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISD-ENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDP 1181 D NIFYSP+S+ A ML LG + QI K L++ ++ + +H++ +L+ + + YD L AN ++ F + +++++Y++ ++ ++F + + K++N W+ES+TN KIKD+F GS N T +VL NAVYFK + F+ ++T ++ F + T V+MMK + ++NF + K++EIP+K ++ ++ LP + L + +L + L + + L +P+FK+D + +L + +G+ D FDP +AD G+S + L V K +HK+F++VNE G EAAAAT + + S E +F D PFL + H+ ++I+F GR+ P Sbjct: 23 DNNIFYSPISMMTALAMLQLGAKGNTEKQIEKVLQFNETTKKTTEKSAHCHDEENVHEQFQKLMTQLNKSNDAYD---LKAANSIYGAKGFPFVQTFLEDIKEYYQANVESLDFEHAAEESEKKINSWVESQTNGKIKDLFPNGSLNRSTIMVLVNAVYFKGQWNHKFDEKHTTEEKFWLNKNTSKPVQMMKQNIEFNFMFLEDVQAKIVEIPYKGKELSMIVLLPVEINGLKQLEEQLTADKLLEWTRAENMHMTELYLSLPRFKVDEKYDLPIPLEHMGMVDAFDPQKADFSGMSSTQGLVVSKVLHKSFVEVNEEGTEAAAATGVEVSLTSAQIAE-----DFCCDHPFLFFIIHRKTNSILFFGRISSP 387
BLAST of SERPIN domain-containing protein vs. Ensembl Mouse
Match: Serpinb11 (serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 11 [Source:MGI Symbol;Acc:MGI:1914207]) HSP 1 Score: 184.111 bits (466), Expect = 1.427e-53 Identity = 122/377 (32.36%), Postives = 206/377 (54.64%), Query Frame = 3 Query: 99 LQENKDG-NIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYK------KSKNEIHKEISEL----LDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTSPT--AIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKL--RQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGIS-DENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDP 1181 L N G NIF+SPL+ A MLLLGT +S+ Q+ K L Y K+K + E S++ D A+I + Q LS+AN ++ + Y +K Y+++++ ++F T K +N W+++KTN KI ++F +G+ + + +VL +A+YFK +++ F+ TV FH V V MM +G + A + ++VLE+P+ N ++R ++ LP ++ + L L+ N + R+V + +PKF + + +L L+ LG++DIF+ ADL G+S D+ L++ K +HK+++DVNE G EAAAAT SI +P T++F + PFL ++ +S + I+F G+ P Sbjct: 19 LSSNNVGENIFFSPLTTFYALSMLLLGTRGKSAEQMEKVLHYDSFSGVLKAKTKNSSECSQVGVMHPDFRALISHINQQNSLSVANRIYGTRSISFHKQYVRCCEKLYQAKLQTVDFELSTEETRKSINAWVKNKTNGKITNLFAKGTIDPSSVMVLVSAIYFKGQWQNKFQKRETVKAPFHMGVGKSAVVNMMYQTGTFKLAIIKEPEMQVLELPYANNKLRMIILLPVGTASVSQIEKHLNVKMLREWTNPSNMVEREVD-VHIPKFSLSVKYDLNTLLKSLGMRDIFNVANADLSGMSPDKGLYLSKVVHKSYVDVNEEGTEAAAATGESISVKRLPV-----TVQFTANCPFLFFIWDESGN-ILFAGKFASP 388
BLAST of SERPIN domain-containing protein vs. Ensembl Mouse
Match: Serpinb1c (serine (or cysteine) peptidase inhibitor, clade B, member 1c [Source:MGI Symbol;Acc:MGI:2445363]) HSP 1 Score: 182.57 bits (462), Expect = 3.175e-53 Identity = 121/370 (32.70%), Postives = 197/370 (53.24%), Query Frame = 3 Query: 93 TVLQENKDGNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINF--TSPTAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQ-RFELNSVXXXXXXXXXXXXXXSLKLRQVS-TLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGIS-DENLFVDKAIHKTFLDVNEHGIEAAAATAMSI--CCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDP 1181 T+ + N GN +SP+SIS+A M+ LG ++ Q+ K L + S +IH + L TA + L +AN L+ + + Y +QK Y +++ ++F S A KE+N W++ +T +KI+++F G +++T+LVL NA YFK ++ F +T D F K TVKMM + F L KVLE+P++ ++ ++ LP E + K+ L+ L L+ + +++PKFK++ L +G LGVQD+F ++ADL G+S +LF+ K +HK++++VNE G E AA ++ CC+ MP +EF VD PFL + H ++F+GRV P Sbjct: 18 TLNESNPTGNTIFSPVSISSALAMVYLGARGSTAAQLSKTLHFD-SAEDIHSQFQSL---TAEVSKRGASHTLKLANRLYGEKTYNFLPEYLASIQKTYSADLALVDFQHASEDARKEINQWVKGQTEEKIQELFAVGVVDSMTKLVLVNATYFKGMWQKKFMARDTTDAPFRLSKKVTKTVKMMYLKNNLPFGYIPDLKCKVLEMPYQGGELSMVILLPEDIEDETTGLEEIEKQLTLEKLQECENLQNIDVCVKLPKFKMEESYILNSNLGQLGVQDLFSSSKADLSGMSGSRDLFISKIVHKSYVEVNEEGTETDAAMPGTVVGCCL-MP-------MEFTVDHPFLFFIRHNPTAHVLFLGRVCSP 375
BLAST of SERPIN domain-containing protein vs. Ensembl Mouse
Match: Serpinb6c (serine (or cysteine) peptidase inhibitor, clade B, member 6c [Source:MGI Symbol;Acc:MGI:2145481]) HSP 1 Score: 179.489 bits (454), Expect = 6.022e-52 Identity = 113/371 (30.46%), Postives = 198/371 (53.37%), Query Frame = 3 Query: 96 VLQENKDGNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKN----EIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTSPT--AIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXX--XXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISD-ENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDP 1181 +L E++ N+F SP+SIS+A M+LLG ++ QI +AL K + ++H+ LL + +Y L AN LF + F I ++++ KFY++EM++++F T + + +N W+ KT DKIK++ G+ ++ T L+L NAVYFK ++ F E+T + F + V+MM + ++ K+L +P+ ++ ++ LP + EL++V ++ ++ +K +V +P FK++ ++KD++ LG+ D F+ RAD GIS + LF+ IHK+ ++VNE G EA AAT + + S T F V+ PF+ + H + I+F+GR+ P Sbjct: 19 ILGEDRSKNVFLSPISISSALVMVLLGAKGTTAIQITQALSLGKCSSSEDGDVHQGFQLLLSEVNKTGTQYS---LKAANRLFGEKTFDILASFKDSCHKFYEAEMEELDFKGATEQSRQHINTWVAKKTEDKIKELLSPGTIHSNTPLILVNAVYFKGKWEKQFNKEDTREMPFKVSKNEEKPVQMMFQKSTFKMTYVEEISTKILLLPYVGNELNMIIMLPDEHVELSTVEKEITHEKFIEWTRLDRMKGEKVEVF-LPWFKLEENYDMKDVLCKLGMTDAFEEGRADFSGISSKQGLFLSNVIHKSVVEVNEEGSEATAATTIVLKG------SSRSTPCFCVNRPFIFFIQHIKTNEILFLGRLSSP 379
BLAST of SERPIN domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9JLD2|NEUS_RAT (Neuroserpin OS=Rattus norvegicus OX=10116 GN=Serpini1 PE=1 SV=1) HSP 1 Score: 185.652 bits (470), Expect = 3.941e-53 Identity = 126/368 (34.24%), Postives = 216/368 (58.70%), Query Frame = 3 Query: 108 NKDGNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTSPTAIKE-VNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDS----QLG--LKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISD-ENLFVDKAIHKTFLDVNEHGIEAAAATAM-SICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDPK 1184 +D NI +SPLSI+ A ++ LG + +I ++ Y+ K+ +E S L D ++++ E Q + IAN LF+QN F I + + ++ ++ +E+ ++F+ A+ +N W+E+ TN +KD+ G F+ +T L L NAVYFK N+K F ENT SF KD ++++ + MM G++ + E S + G +VLEIP++ ++ +L L Q L ++ LK ++ NS+K ++V +P+F ++ +++LKD++ LGV +IF + A+L +SD + LF+ KA+HK+F++VNE G EAA A+ M +I M++ F + IVD PFL + ++ I+F+GRV P+ Sbjct: 41 GEDENILFSPLSIALAMGVMELGAQGSTLKEIRHSMGYESLKS--GEEFSFLRDFSSMVSAEEGQYVMKIANSLFVQNGFHINEEFLQMMKMYFNAEVNHVDFSENVAVANYINKWVENYTNSLLKDLVSPGDFDAVTHLALINAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEVPLATLEPLLKPQLIEEWANSVKKQKVEVY-LPRFTVEQEIDLKDILKALGVTEIFIKD-ANLTAMSDKKELFLSKAVHKSFIEVNEEGSEAAVASGMIAISRMAVLF------PQVIVDHPFLFLIKNRKTGTILFMGRVMHPE 398
BLAST of SERPIN domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9CQV3|SPB11_MOUSE (Serpin B11 OS=Mus musculus OX=10090 GN=Serpinb11 PE=2 SV=1) HSP 1 Score: 184.111 bits (466), Expect = 9.979e-53 Identity = 122/377 (32.36%), Postives = 206/377 (54.64%), Query Frame = 3 Query: 99 LQENKDG-NIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYK------KSKNEIHKEISEL----LDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTSPT--AIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKL--RQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGIS-DENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDP 1181 L N G NIF+SPL+ A MLLLGT +S+ Q+ K L Y K+K + E S++ D A+I + Q LS+AN ++ + Y +K Y+++++ ++F T K +N W+++KTN KI ++F +G+ + + +VL +A+YFK +++ F+ TV FH V V MM +G + A + ++VLE+P+ N ++R ++ LP ++ + L L+ N + R+V + +PKF + + +L L+ LG++DIF+ ADL G+S D+ L++ K +HK+++DVNE G EAAAAT SI +P T++F + PFL ++ +S + I+F G+ P Sbjct: 19 LSSNNVGENIFFSPLTTFYALSMLLLGTRGKSAEQMEKVLHYDSFSGVLKAKTKNSSECSQVGVMHPDFRALISHINQQNSLSVANRIYGTRSISFHKQYVRCCEKLYQAKLQTVDFELSTEETRKSINAWVKNKTNGKITNLFAKGTIDPSSVMVLVSAIYFKGQWQNKFQKRETVKAPFHMGVGKSAVVNMMYQTGTFKLAIIKEPEMQVLELPYANNKLRMIILLPVGTASVSQIEKHLNVKMLREWTNPSNMVEREVD-VHIPKFSLSVKYDLNTLLKSLGMRDIFNVANADLSGMSPDKGLYLSKVVHKSYVDVNEEGTEAAAATGESISVKRLPV-----TVQFTANCPFLFFIWDESGN-ILFAGKFASP 388
BLAST of SERPIN domain-containing protein vs. UniProt/SwissProt
Match: sp|Q5SV42|ILEUC_MOUSE (Leukocyte elastase inhibitor C OS=Mus musculus OX=10090 GN=Serpinb1c PE=1 SV=1) HSP 1 Score: 182.57 bits (462), Expect = 2.221e-52 Identity = 121/370 (32.70%), Postives = 197/370 (53.24%), Query Frame = 3 Query: 93 TVLQENKDGNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINF--TSPTAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQ-RFELNSVXXXXXXXXXXXXXXSLKLRQVS-TLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGIS-DENLFVDKAIHKTFLDVNEHGIEAAAATAMSI--CCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDP 1181 T+ + N GN +SP+SIS+A M+ LG ++ Q+ K L + S +IH + L TA + L +AN L+ + + Y +QK Y +++ ++F S A KE+N W++ +T +KI+++F G +++T+LVL NA YFK ++ F +T D F K TVKMM + F L KVLE+P++ ++ ++ LP E + K+ L+ L L+ + +++PKFK++ L +G LGVQD+F ++ADL G+S +LF+ K +HK++++VNE G E AA ++ CC+ MP +EF VD PFL + H ++F+GRV P Sbjct: 18 TLNESNPTGNTIFSPVSISSALAMVYLGARGSTAAQLSKTLHFD-SAEDIHSQFQSL---TAEVSKRGASHTLKLANRLYGEKTYNFLPEYLASIQKTYSADLALVDFQHASEDARKEINQWVKGQTEEKIQELFAVGVVDSMTKLVLVNATYFKGMWQKKFMARDTTDAPFRLSKKVTKTVKMMYLKNNLPFGYIPDLKCKVLEMPYQGGELSMVILLPEDIEDETTGLEEIEKQLTLEKLQECENLQNIDVCVKLPKFKMEESYILNSNLGQLGVQDLFSSSKADLSGMSGSRDLFISKIVHKSYVEVNEEGTETDAAMPGTVVGCCL-MP-------MEFTVDHPFLFFIRHNPTAHVLFLGRVCSP 375
BLAST of SERPIN domain-containing protein vs. UniProt/SwissProt
Match: sp|Q90935|NEUS_CHICK (Neuroserpin OS=Gallus gallus OX=9031 GN=SERPINI1 PE=1 SV=1) HSP 1 Score: 182.57 bits (462), Expect = 5.072e-52 Identity = 124/367 (33.79%), Postives = 213/367 (58.04%), Query Frame = 3 Query: 111 KDGNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTSPTAIK-EVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDS----QLG--LKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISD-ENLFVDKAIHKTFLDVNEHGIEAAAATAM-SICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDPK 1184 +D NI + PLSI+ A M+ LG + + +I +L + KN +E + L D + + E L++AN L++QN F + + + ++K++K+E++ I+F+ A+ +N W+E+ TN+ IKD F+ LT LVL NA+YFK N+K F ENT SF KD +T++ + MM G++ + E S + G +VLEIP++ ++ ++ L Q L ++ +K + + NS+K ++V +P+F ++ +++LKD++ LG+ ++F ADL +SD + L++ KA HK FL+VNE G EAAAA+ M +I M++ + + IVD PF V ++ ++F+GRV P+ Sbjct: 42 EDENILFCPLSIAIAMGMIELGAHGTTLKEIRHSLGFDSLKN--GEEFTFLKDLSDMATTEESHYVLNMANSLYVQNGFHVSEKFLQLVKKYFKAEVENIDFSQSAAVATHINKWVENHTNNMIKDFVSSRDFSALTHLVLINAIYFKGNWKSQFRPENTRTFSFTKDDETEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMIVLSRQEVPLVTLEPLVKASLINEWANSVKKQKVEVY-LPRFTVEQEIDLKDVLKGLGITEVFS-RSADLTAMSDNKELYLAKAFHKAFLEVNEEGSEAAAASGMIAISRMAVLY------PQVIVDHPFFFLVRNRRTGTVLFMGRVMHPE 398
BLAST of SERPIN domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9UIV8|SPB13_HUMAN (Serpin B13 OS=Homo sapiens OX=9606 GN=SERPINB13 PE=1 SV=2) HSP 1 Score: 181.03 bits (458), Expect = 1.301e-51 Identity = 115/382 (30.10%), Postives = 206/382 (53.93%), Query Frame = 3 Query: 99 LQENKDGNIFYSPLSISAAFCMLLLGTNDESSNQI---------IKALKYKKSKNEI-------HKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTSPT--AIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQRFELNSV--XXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISD-ENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDP 1181 L++ DGNIF+SP+ I A M+LLGT +++Q+ K+ + K + E+ H++ + L + + + N+Y +L+I N LF + + Y + ++K+Y + ++ ++F + + K++N W+ESKTN+KIKD+F +GS ++ T+LVL N VYFK + F+ ENT ++ F + T +V+MM S ++F L K+L IP+KN + + LP L + ++ ++ R+V+ L +P+F+++ +L+ ++ +G+ D F ++AD G+S L+ K +H +F+ V E G EAAAAT + S P +E+ + PFL + H +++I+F GR P Sbjct: 19 LKKTNDGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEKETKSSRIKAEEKEVIENTEAVHQQFQKFLTEISKLTNDY---ELNITNRLFGEKTYLFLQKYLDYVEKYYHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNMVYFKGQWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKNNDLSMFVLLPNDIDGLEKIIDKISPEKLVEWTSPGHMEERKVN-LHLPRFEVEDGYDLEAVLAAMGMGDAFSEHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSAPGHENVH-----CNHPFLFFIRHNESNSILFFGRFSSP 391
BLAST of SERPIN domain-containing protein vs. TrEMBL
Match: C3YTM6 (SERPIN domain-containing protein OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_66649 PE=3 SV=1) HSP 1 Score: 208.764 bits (530), Expect = 7.365e-60 Identity = 124/365 (33.97%), Postives = 197/365 (53.97%), Query Frame = 3 Query: 99 LQENKDGNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINF-TSPTAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEV--PKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISDE-NLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDP 1181 L + DGNIF+SP SISAA M +G +++Q+ + L ++ + H+ S L + + + L AN LF Q K++D++ + ++Y + M+K++F + +N W+ ++T KI D+ +G N LTRLVL NAVYFK ++ F+ T D+ F +T M G + A+ L ++LE+P+ ++ + LP Q F L + L L + S L++V +L+V PKF++ L+LKD + LG+ D+F ADL G++ E L V + +HK F++VNE G EAAAATA+ + S F S F+V+ PFL + HK I+F+GRV +P Sbjct: 21 LSQRTDGNIFFSPYSISAALAMTYMGARHTTADQMAEVLHL--TEGDFHQAFSNL---SRAMFGNLKKHTLVQANKLFGQQGMKLEDDFLSGTSRYYNARMEKVDFFDEERSRSRINSWVSTQTKRKINDLIPKGVLNALTRLVLVNAVYFKGTWQTQFDPRETYDRKFFASSGNHVTTPTMHQRGKFRMADLPNLRCRMLELPYAGDELAMFVILPKQMFGLKDLEAVLTSEALLDATRSKSLQEVRSLDVALPKFRLTHALSLKDQLTALGMTDLFSMETADLSGVTGEKGLHVSEVLHKAFVEVNEEGSEAAAATAVVMRGRSGNFGRS-----FMVNRPFLFFIQHKPTGTILFLGRVTNP 375
BLAST of SERPIN domain-containing protein vs. TrEMBL
Match: Q6GLT7 (MGC84260 protein OS=Xenopus laevis OX=8355 GN=serpini1 PE=2 SV=1) HSP 1 Score: 207.608 bits (527), Expect = 5.434e-59 Identity = 132/366 (36.07%), Postives = 217/366 (59.29%), Query Frame = 3 Query: 111 KDGNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTSPTAI-KEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAE----DSQLG--LKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISD-ENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDPK 1184 +D NI +SPLS + A M+ LG S +I L Y K KN +E S L D ++++ + LSIAN L++QN F I D + ++K++K+E++ ++F+ +A+ +N W+E+ TN++I+D+F FNNLT+LVL NA+YFK N+K F ENT SF KD ++++ + MM G++ + E ++ G +VLE+P++ ++ ++ L Q L ++ LK ++ NS+K ++V +P+FK++ +NLKD++ LG+ IF ADL ISD ++LFV K +HK+FL+VNE G EAAA++ M Y + IVD PF + ++ +++F+GRV P+ Sbjct: 42 EDENIIFSPLSTAIALGMVELGARGSSLKEIRHVLGYDKLKNG--EEFSLLKDLSSMLTAQEKHYVLSIANSLYLQNGFHISDKFIQLMKKYFKAEVENVDFSQGSAVASHINLWVENHTNNRIRDLFTADDFNNLTKLVLVNALYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQKGEFYYGEFTDGSNEAGGVYQVLELPYEGEEISLIIILSRQEVPLATIEPLLKAPLIEEWANSVKKQKVEVY-LPRFKVEEVVNLKDILMRLGITKIFS-GEADLSAISDSKDLFVAKVVHKSFLEVNEEGAEAAASSGMIANSRMAVLYP-----QVIVDHPFFFLIRNRKTGSVLFMGRVMHPE 398
BLAST of SERPIN domain-containing protein vs. TrEMBL
Match: A2VD89 (LOC734183 protein OS=Xenopus laevis OX=8355 GN=serpini1 PE=2 SV=1) HSP 1 Score: 204.142 bits (518), Expect = 9.431e-58 Identity = 130/365 (35.62%), Postives = 215/365 (58.90%), Query Frame = 3 Query: 114 DGNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFT-SPTAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAE----DSQLG--LKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISD-ENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDPK 1184 D NI +SPLS + A M+ LG S +I L Y K KN +E S L D ++++ + LSIAN L++QN F I D + ++K++K+E++ ++F+ T +N W+E+ TN++I+D+F FNNLT+LVL NA+YFK N+K F ENT SF KD ++++ + MM G++ + E ++ G +VLE+P++ ++ ++ L Q L ++ LK + ++ S+K ++V +P+FK++ +NLK+++ LG+ IF ADL ISD ++LFV KA+HK+FL++NE G EAAA++ M Y + IVD PF + ++ +++F+GRV P+ Sbjct: 43 DENIIFSPLSTAIALGMVELGARGSSLKEIRHVLGYDKLKNG--EEFSLLKDLSSMLTAQEKHYVLSIANSLYLQNGFHISDKFIQLMKKYFKAEVENVDFSQGSTVANHINLWVENHTNNRIRDLFTADDFNNLTKLVLVNAMYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQKGEFYYGEFTDGSNEAGGVYQVLELPYEGDEISLIIVLSRQEVPLATIEPLLKAHLIEEWAKSVKKQKVEVY-LPRFKVEEVVNLKEVLMRLGITKIFS-GEADLSAISDSKDLFVAKAVHKSFLEINEEGSEAAASSGMIANSRMAVLYP-----QVIVDHPFFFVIRNRKTGSVLFMGRVMHPE 398
BLAST of SERPIN domain-containing protein vs. TrEMBL
Match: Q2MDE1 (Neuroserpin OS=Xenopus laevis OX=8355 GN=serpin I1 PE=2 SV=1) HSP 1 Score: 203.756 bits (517), Expect = 1.204e-57 Identity = 130/365 (35.62%), Postives = 215/365 (58.90%), Query Frame = 3 Query: 114 DGNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFT-SPTAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAE----DSQLG--LKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISD-ENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDPK 1184 D NI +SPLS + A M+ LG S +I L Y K KN +E S L D ++++ + LSIAN L++QN F I D + ++K++K+E++ ++F+ T +N W+E+ TN++I+D+F FNNLT+LVL NA+YFK N+K F ENT SF KD ++++ + MM G++ + E ++ G +VLE+P++ ++ ++ L Q L ++ LK + ++ S+K ++V +P+FK++ +NLK+++ LG+ IF ADL ISD ++LFV KA+HK+FL++NE G EAAA++ M Y + IVD PF + ++ +++F+GRV P+ Sbjct: 43 DENIIFSPLSTAIALGMVELGARGSSLKEIRHVLGYDKLKNG--EEFSLLKDLSSMLTAQEKHYVLSIANSLYLQNGFHISDKFIQLMKKYFKAEVENVDFSQGSTVANHINLWVENHTNNRIRDLFTADDFNNLTKLVLVNAMYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQKGEFYYGEFTDGSNEAGGVYQVLELPYEGDEISLIIVLSRQEVPLATIEPLLKAHLIEEWAKSVKKQKVEVY-LPRFKVEEVVNLKEVLMRLGITKIFS-GEADLSAISDSKDLFVAKAVHKSFLEINEEGSEAAASSGMIANSRMAVLYP-----QVIVDHPFFFVIRNRKTGSVLFMGRVMHPE 398
BLAST of SERPIN domain-containing protein vs. TrEMBL
Match: A0A496UZV9 (Serpin family protein OS=Gammaproteobacteria bacterium OX=1913989 GN=DRR08_28490 PE=3 SV=1) HSP 1 Score: 202.601 bits (514), Expect = 6.572e-57 Identity = 120/375 (32.00%), Postives = 202/375 (53.87%), Query Frame = 3 Query: 96 VLQENKDGNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTSP--TAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRF----------LLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISD-ENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDP 1181 ++ + K N+F+SP S+S A M G ++ Q+ K L + + + E+H L + + ++ IAN + Q + +N+++ ++ +Y++++K+++F + T KE+N W+E +TN KIK++ + G ++LTRLVL NA+YFK N+ F+ +T SF + V MM + + E+ +L ++VLE+P+ F ++ LP QR L + LK +L+ +++L+ RQ + +PKFKI T NL + +G+ D F+ N AD GI + L + +HK F+DVNE G EAAAAT + I +P T EF D PF+ + H S +I+F+GRV +P Sbjct: 57 LIAKGKSDNLFFSPYSLSTALAMTYAGAGGRTATQMSKVLHFPEEQAELHTAFYHLQNDVNDAAKKASNLEIRIANAFWGQKGYPFLENFKDSVENYYQAKLKEVDFRTAYQTIRKEINAWVEEQTNKKIKNLIKPGLIDHLTRLVLVNAIYFKGNWASPFKTGDTKKASFWVTSTKDVRVPMMTQKNHFGYTENRRLQVQVLELPYGGNSQDFPSYGDNNISMIVLLPRQRNGLAKLEKSLKGKNLEQWLDNLQWRQKVKVFLPKFKISTGFNLSKTLASMGMPDAFNEN-ADFSGIDGVKELHITSIVHKAFVDVNEKGTEAAAATGVMIGTRGLP----PPTPEFRADHPFIFLIRHNSTKSILFMGRVVNP 426
BLAST of SERPIN domain-containing protein vs. Ensembl Cavefish
Match: serpini1 (serpin family I member 1 [Source:NCBI gene;Acc:103031312]) HSP 1 Score: 165.622 bits (418), Expect = 1.991e-46 Identity = 102/366 (27.87%), Postives = 206/366 (56.28%), Query Frame = 3 Query: 120 NIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTSPTAIKE-VNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAE----DSQLG--LKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISDE-----NLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDP 1181 NI +SPLS++ A M+ LG S +I +A+ Y + + +E S L + T + + Q + +AN LF+Q+ ++ +++++ ++++ ++F+ A+ + +N W+++ T KI D+ F+++TR+ L NA+YF+ ++K+ F ENT SF KD +++ MM GD+ + E ++ G +VLE+P++ + ++ LP Q L ++ ++ L + N++K ++V +P+FK++ +++L+D + LG+++IF + ADL ++ E +LF+ KA+ K++L+V E G E AA + M ++ Y + + D PF + ++ +++F+GRV +P Sbjct: 46 NIIFSPLSVALALGMVELGARGSSLQEIRQAVGYSNFRED--EEFSVLRNLTLALSGDEAQYVVRLANSLFLQSGVHFNADFLRLMKQYFHAQVETVDFSESAAVAQHINTWVQNHTESKIHDLVSADDFSSVTRITLVNAMYFRGSWKNQFRPENTRTFSFSKDDGSEVQTLMMYQQGDFYYGEFSDGSAEAGGVYQVLEMPYEGEDVSMMIVLPRQEVPLATLEPIIRPQLLDDWANNVKKQKVEVY-LPRFKVEQKIDLRDTLQQLGIKNIFTKD-ADLSAMTAEREDGSDLFIGKAVQKSYLEVTEEGAEGAAGSGMIALTRTLVLYP-----QVMADHPFFFVIRNRRTGSLLFMGRVMNP 402
BLAST of SERPIN domain-containing protein vs. Ensembl Cavefish
Match: SERPINB8 (leukocyte elastase inhibitor-like [Source:NCBI gene;Acc:103033961]) HSP 1 Score: 160.229 bits (404), Expect = 8.151e-45 Identity = 116/378 (30.69%), Postives = 206/378 (54.50%), Query Frame = 3 Query: 90 KTVLQENKDGNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTS--PTAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPT---------QRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISD-ENLFVDKAIHKTFLDVNEHGIEAAAATA--MSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDP 1181 K + NK GN+FYSPLSIS+A M+ LG + Q+ + L++ K+ +++H ++L+ + Y LS+AN L+ + ++ + + + ++ Y +E++ ++F S A ++N W+E +T +KIKD+ +G + LTRLVL NA+YFK +++ F T + F + K V+MM + A + ++LE+P+ + L+ LPT ++ E N L E ++++++++ QVS +P+FK++ ++K L+ +G+ D FD + D +S ++L + K +HK+F++VNE G EAAAATA M + C +P F+ D PFL + H + +I+F GR P Sbjct: 17 KKIRDGNKQGNLFYSPLSISSALAMVSLGAAGNTEAQMSETLQFSKANDDVHTGFNKLMSQLNKAGAPY---SLSLANRLYGEQTYQFVEKFLGDTKQHYSAELEAVDFKSNAEAARVKINKWVEKQTQEKIKDLLAKGVVDELTRLVLVNAIYFKGSWEKKFNSNGTREVPFRLNKKDTKPVQMMNQKAKFPLAFTPDMNCQILEMPYAGKDLSMLIILPTEMADDTTGLEKIEKNLTYENLMEWTRPDMMDNVEV-QVS---LPRFKLEDTYDMKGLLVSMGMVDAFDRVKCDFSRMSPCDDLVLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCAMLP------PERFVADHPFLFFIRHNATKSILFCGRFSSP 381
BLAST of SERPIN domain-containing protein vs. Ensembl Cavefish
Match: serpinb1l3 (leukocyte elastase inhibitor-like [Source:NCBI gene;Acc:103029950]) HSP 1 Score: 156.762 bits (395), Expect = 1.561e-43 Identity = 115/374 (30.75%), Postives = 203/374 (54.28%), Query Frame = 3 Query: 90 KTVLQENKDGNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINF--TSPTAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQ-RFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEV----PKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISD-ENLFVDKAIHKTFLDVNEHGIEAAAATA--MSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDP 1181 K + + NK GN+FYSPLSIS+A M+ LG + Q+ + L++ K+K +IH ++LL++ Y L++AN L+ + ++ + + + ++ Y +E++ +F S A +N W+E +T +KIKD+ EG + LTRLVL NA+YFK N++ F T + F + K V+MM ++ A + ++LE+P++ + L LP + + + + + +N + + + T+ V P+FK++ ++K+L+ +G+ D FD + D +S +NL + K +HK+F++VNE G EAAAATA M++ C+ + F+ D PFL + H + +I+F GR P Sbjct: 17 KKIREGNKQGNMFYSPLSISSALAMVSLGAAGNTEAQMSETLQFNKAKVDIHIGFNQLLNELNKAGAPYS---LTLANRLYGEQTYQFVEKFLADTKQHYHAELETADFKSNSEAARVHINTWVEKQTQEKIKDLLAEGVVDELTRLVLVNAIYFKCNWEKRFLSFETREVQFKLNKKETKPVQMMNQEERFHLALIPDINCQILEMPYEGNDLSMLFILPNEIQDDTTGLEKLEQSLTYENFMEWTRPDMMETVNVEVSLPRFKLEQTYDMKELLVSMGMVDAFDQVKCDFSRMSPCDNLVLSKVVHKSFVEVNEEGTEAAAATAAIMTLDCLLIC------QRRFVADHPFLFFIRHNATGSILFCGRFSSP 381
BLAST of SERPIN domain-containing protein vs. Ensembl Cavefish
Match: serpinc1 (serpin family C member 1 [Source:NCBI gene;Acc:103038850]) HSP 1 Score: 154.066 bits (388), Expect = 9.480e-42 Identity = 111/363 (30.58%), Postives = 191/363 (52.62%), Query Frame = 3 Query: 120 NIFYSPLSISAAFCMLLLGTNDESSNQIIKALKY----KKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTSPTAIK--EVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGI---SDENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDP 1181 NIF SPLSIS AF M LG + + QI+K ++ +K+ +++H ++L + +++ +L AN LF + + I +N+QN + Y +++ +NF I ++N WI KT KI D +GS + +VL N +YFK +K+ F+ ++ + FH K V MM + + + + +KVLE+P+ + +L LP + L V + + L N N++ V+ +++P+F+I+ +LK+ M +G+ +F A L GI D +++ A HK FL+VNE G EAAAATA+ S+ + F+ ++PFLL + + + I+F GR+ +P Sbjct: 111 NIFMSPLSISTAFAMTKLGACNSTLEQIMKVFEFDTIKEKTSDQVHFFFAKL--NCRLYRKKHNTVELVSANRLFGEQSLNINENFQNISEVVYGAKLMPLNFKEKPEISRLKINQWISEKTKGKINDTLPQGSIDATAVMVLVNTIYFKGQWKNKFDKKDVMSLQFHVSSTKKCQVHMMYKEAKFQYKKFPEDKVKVLELPYNGGGISMVLVLPMKDSNLTEVEKIITYSKLTNWTNTMSETTVA-VQIPRFRIEDSFSLKEKMRDMGLNHLFSAEHASLPGIVEGVDNGIYISDAYHKAFLEVNEEGSEAAAATAVVALGRSLNVNRES----FVANKPFLLFIREATINTIIFAGRISNP 466
BLAST of SERPIN domain-containing protein vs. Ensembl Cavefish
Match: SERPINA4 (alpha-1-antitrypsin homolog [Source:NCBI gene;Acc:103041583]) HSP 1 Score: 150.984 bits (380), Expect = 9.777e-41 Identity = 115/365 (31.51%), Postives = 190/365 (52.05%), Query Frame = 3 Query: 105 ENKDGNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKK----SKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTSP-TAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGIS-DENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDP 1181 E K NIF+SPLSIS A ML LG + +QI L Y NE ++ + +LD + D+ L + + ++ +FK D + ++Q FY+ E ++++ P A++E+N +I KT D I DM + + + T ++L N +YF+ +K FE T FH D TK+TV MM+ +G Y+F D ++++P+K +L LP + ++ + + ++ +K + L R V +PKF I +L + + +G+ D F + AD GIS D L K +HK L V+E G EAAAAT + I +SMP ++ PFL+ + S +I+F+G++++P Sbjct: 101 EAKGKNIFFSPLSISMALSMLALGAKGNTHSQIFSTLGYSTLTPDQVNEGYEHLLHMLDHSQ------DEMLLEAGSAVAVREDFKPVDKFLKDVQHFYQGEAFTVDYSKPEVAVQEINKYIAKKTKDMITDMVK--TLDPQTVMMLINYIYFRGKWKKPFEQRFTQKADFHVDDNTKVTVDMMQNTGRYHFYIDWDNSTSIIKVPYKG-NASMMLILPDEG-KMQDLERNISKDHIKYWHDKLSYRVVD-FSMPKFSISASSSLAETLQEMGMVDAF-LDIADFSGISVDTKLLASKVLHKAVLKVDEKGTEAAAATTIEIIPLSMP-------RTITLNRPFLVFIVEDSTKSILFMGKINNP 446
BLAST of SERPIN domain-containing protein vs. Ensembl Sea Lamprey
Match: SERPINB1 (serpin family B member 1 [Source:HGNC Symbol;Acc:HGNC:3311]) HSP 1 Score: 166.392 bits (420), Expect = 7.543e-48 Identity = 111/374 (29.68%), Postives = 191/374 (51.07%), Query Frame = 3 Query: 90 KTVLQENKDGNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTSP--TAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPT----QRFELNSVXXXXXXXXXXXXXXSLKLRQVST-LEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGI-SDENLFVDKAIHKTFLDVN--EHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDP 1181 +T+ GN+F+SPLSISAA M+LLG ++S Q+ K L Y+ +++H+ LL + + L +AN L+ + +F + QKFY +++ ++FT K++N W+E KT+ KIKD+ +EG+ + +TRLV+ NAVYFK + F +NT +FH + + V+MM + + L VLE+P+ + ++ LP + L + +L +L+ + +R L +P+F+++ L + +LG+ D+F P ADL G+ + +LFV H+ F++VN AA A M + C +MP + +F D PF+ + +++F+GR P Sbjct: 17 RTLGAREVGGNVFFSPLSISAALAMVLLGAKGQTSEQMSKVLCYE-GVSDVHEAFKGLL---GTLKSPGAGCVLRVANRLYGEKSFGFLKGFLQATQKFYDAKLAAVDFTKSFDGVRKKINAWVEEKTDGKIKDLLEEGTLDVMTRLVIVNAVYFKGKWTKKFNSQNTTQSNFHLNQRETKQVQMMSQKNTFQHGFVQNMNLNVLELPYVGNALSMIILLPAAIEDETNGLEKLERELNLQNLQTWTSPTTMRSGDVLLHLPRFRLEQSYTLNKPLSILGMGDLFSPLTADLSGMDGNRDLFVSHVAHRAFVEVNEEGTEAAAATAVTMKLRC-AMP---TQPPFKFCADHPFVFLIRDNRNGSVLFLGRYTSP 382
BLAST of SERPIN domain-containing protein vs. Ensembl Sea Lamprey
Match: SERPINB1 (serpin family B member 1 [Source:HGNC Symbol;Acc:HGNC:3311]) HSP 1 Score: 152.91 bits (385), Expect = 3.030e-43 Identity = 92/301 (30.56%), Postives = 152/301 (50.50%), Query Frame = 3 Query: 309 LSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTSP--TAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLP------TQRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGI-SDENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCM-SMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDP 1181 L +AN L+ + F + + +KFY++E+ ++FT KE+N W+E T KIKD+ EG+ + TRLV+ NAVYFK + F ++NT +F+ + V+MM + + LKVLE+P+ ++ ++ LP T E L +++ V L +P+F+++ L + + LG+ D+F P ADL G+ + +LFV H+ F++VNE G EAAAAT +S+ M +MP + F D PF+ + +++F+GR P Sbjct: 29 LRLANRLYGEKTFGFLKEFLDMTEKFYEAELAAVDFTGAFNDVRKEINSWVEGNTEGKIKDILAEGTVGSTTRLVVVNAVYFKGKWTTPFNLQNTAQTTFYLSKRETKPVQMMFQEKKFRHGFVPHMNLKVLELPYVGNELSMIILLPAAIEDETTGLEKLERELNLLNLQTWTSPTTMRSGDV-LLHLPRFRLEQSYTLNEPLSSLGMGDLFSPLTADLSGMDGNRDLFVSHVAHRAFVEVNEEGTEAAAATTISVMLMCAMP---TQPPFTFCADHPFVFLIRDNRNGSVLFLGRYTSP 325
BLAST of SERPIN domain-containing protein vs. Ensembl Sea Lamprey
Match: SERPINB1 (serpin family B member 1 [Source:HGNC Symbol;Acc:HGNC:3311]) HSP 1 Score: 129.798 bits (325), Expect = 1.731e-34 Identity = 93/308 (30.19%), Postives = 158/308 (51.30%), Query Frame = 3 Query: 309 LSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTSP--TAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLK-LRQVST----------LEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISD-ENLFVDKAIHKTFLDVNEHGIEAAAAT---AMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDP 1181 L +AN L+ + + ++ + KFY++E+ +NF A KE+N W+E +T KI+D+ G N+LTRLVL NAVYFK ++ F+ E T D F + K VKMM YNF+ +L + ++E+P++ +++ ++ +P ++ ++ + +LK LRQ ++ L +P+F+++ L + + LG+ +F AD GI+ +L+V HK F++VNE G EAAAAT M C P + D PF+ + S+ +++F+GR P Sbjct: 48 LRMANRLYGEKGYNFLQDFLDSSAKFYRAELAAVNFKGAFEEARKEINAWVEGQTEGKIQDLLASGVVNSLTRLVLVNAVYFKGSWDAKFDPEVTRDAEFKINKNEKKPVKMMYKKAKYNFSHVEELNVNIVELPYEGHKLSMVILVPL------AIEDETTGLEKLESALTLKSLRQWTSPENMSKLEVELHLPRFRLEKSYTLNEHLQRLGMASVFTQGEADFSGINGARDLYVSHVAHKAFVEVNEEGTEAAAATAAIVMMRCARMGPVVRA--------DHPFIFFIRENSSGSVLFLGRFASP 341
BLAST of SERPIN domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006795.1 (pep scaffold:Pmarinus_7.0:GL479006:3227:9631:1 gene:ENSPMAG00000006108.1 transcript:ENSPMAT00000006795.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 130.568 bits (327), Expect = 8.380e-34 Identity = 102/363 (28.10%), Postives = 179/363 (49.31%), Query Frame = 3 Query: 120 NIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYK-----KSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFT-SPTAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLR-QVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISD-ENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDPK 1184 NIF+SPLSI++A ++ G N + ++ AL +K K K + K + L + + +L N +F + + + + +KS ++ ++F S A++ +N +IE T+ K D+ + + T L++ N +YFK ++ + FE + T + F + + V M ++A+D +L V+++P++ L+ +P + EL V + + L+ ++ L L +PKFKI +LK + +G+ +F ADL I+ + L VDK HK+ L VNE G EA A T + I +SMP VD PF++ +Y + A++F+GRV DPK Sbjct: 130 NIFFSPLSIASALGVVAAGANGSTRAELDTALGFKELLHGKKKAKSMKYFARL---NSALYRRSAGFELMGKNVVFSKKGLWLYRQFTRTVAHLFKSNVRSVDFGESKEAVELMNAYIEKVTSKKFTDVISD--VDTATSLMIVNVIYFKGSWANKFEPDLTKNVRFWVNSSYSMMVPTMHQRAKLSYAQDRKLRSTVIKLPYEG-GASMLVIVPHRTEELPKVEESVSQEQLEEWLSLLGPSNHYVQLSLPKFKISVSYDLKAYLSAMGMPSMFSYG-ADLSRITGMQKLHVDKITHKSVLHVNEEGTEAKAETVVGIMPISMP-------PTVTVDRPFVVLIYDEKTRAVIFMGRVADPK 478
BLAST of SERPIN domain-containing protein vs. Ensembl Sea Lamprey
Match: serpind1 (serpin peptidase inhibitor, clade D (heparin cofactor), member 1 [Source:ZFIN;Acc:ZDB-GENE-030711-2]) HSP 1 Score: 121.324 bits (303), Expect = 9.552e-31 Identity = 100/375 (26.67%), Postives = 188/375 (50.13%), Query Frame = 3 Query: 90 KTVLQENKDG-NIFYSPLSISAAFCMLLLGTNDESSNQIIKALKY--------KKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTSPTAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQ-RFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISD-ENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDP 1181 ++V + G N+ +PL IS+ M+ LG N + +I KAL + K + + +HK L + + + + T L A+ L++Q + + +YQ L+K Y +E ++F P ++ +N W+ S T I D + + T ++ N+VYFK ++ F T +SF + K + V+MM+T + D +LG +L++ ++ + +L +P + + L ++ L + L+ + ++ R + +PKF + + NLK+ + LGV ++F N ADL G++ +++ V H+ F+ ++E G EAAA T + P N F+ D PF+ VY +++F+G+V +P Sbjct: 83 RSVSESTPSGENLLLAPLGISSTLGMIALGANGGTHKEIYKALGFESLVDSSSKYNISTVHKLFHRLNHR--LFRHNFGYT-LKSASALYLQRRWPLLPSYQQCLRKTYFAEAHTVDFKDPATVQRINRWVSSATKGTISDAVT--NIDPSTVFLVINSVYFKGPWEIKFSKHQTSVRSFRLNDKETVKVQMMQTKASFLVTTDHELGCDILQLAYQG-NVSMILAVPHKLKGGLKTLERALSFDLLEKWLQAMTNRTRDVI-IPKFNLQQKYNLKNNLKELGVTELFQAN-ADLSGMTGAKDVQVSSFQHQGFIKIDEEGSEAAAVTTVGFT----PLTSHN---RFVADRPFVFIVYEHHTMSVLFLGQVSNP 442
BLAST of SERPIN domain-containing protein vs. Ensembl Nematostella
Match: EDO35632 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKW8]) HSP 1 Score: 189.504 bits (480), Expect = 3.655e-56 Identity = 119/369 (32.25%), Postives = 206/369 (55.83%), Query Frame = 3 Query: 99 LQENKDGNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSK-NEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTSPT--AIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSG--DYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEV--PKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGIS-DENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDP 1181 L ++ N+F+SPLS+S A ++ LG+ ++ QI +K+S+ E H+ + + A++ ++ ++ + N ++ + F+I + + + ++FY SEM +++F + A KEVN W+ +T IK++ G N+LTRL++ NAVYFK +K F ENT +F + +++ + NF D+ + +V+E+P+ ++ LP E + + + K D++ + +L +T+EV PKF++ +L L+ L+ LGV DIFD +ADL GIS + L+V AIHK ++VNE G AAA T + + S+ + NE F D PFL S++HK + AI+F+G+V P Sbjct: 20 LSKSSASNVFFSPLSMSMALGLVYLGSRGTTAIQIANIFGWKESEFEETHRTFKQFHE--ALLTSDLGYGEIQLVNKIWGHDEFEILEEFLHGTREFYHSEMAQVDFVNKAFDARKEVNAWVHQQTKGNIKELIPHGVINSLTRLIIVNAVYFKGVWKKEFGEENTFHAAFFVPESHESKIEVEMMTRKMKVNFYYDADIKCRVVELPYSGDDTAMVIILPE---EPSGIFSLEKSIDVEIMEKWRRLMINTTVEVSIPKFRLSQKLELRSLLQDLGVSDIFDSRKADLSGISAAKGLYVSSAIHKAHIEVNERGTVAAATTGVVMAKRSL---DMNEV--FYADHPFLFSIHHKPSSAILFLGKVMQP 378
BLAST of SERPIN domain-containing protein vs. Ensembl Nematostella
Match: EDO40288 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S7S1]) HSP 1 Score: 185.267 bits (469), Expect = 1.172e-54 Identity = 117/363 (32.23%), Postives = 187/363 (51.52%), Query Frame = 3 Query: 111 KDG--NIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFT--SPTAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEV--PKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISDENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDP 1181 +DG N+FYSP SI A M LG ++ Q+ K + E + + L+ + D Q+ +AN LF Q F+I + ++ ++ + +EM +++ S A VN W+E KT DKIK++ EG FN T L L NAVYFK ++ F T F ++ V+ M S ++ + E S LG +++E+P+ ++ ++ LP + L + + L + L+ + SL+ +EV PKF + + +L + + +G D+F P +ADL GIS L V + +HK F++VNE G AAAAT + I MSMP F + PFL + H A++F+GR+ P Sbjct: 24 QDGQTNLFYSPASIVVALAMTYLGARGNTATQMTKTFHFPTDVPEKFHDFLQALNAS-----NSDGNQILMANRLFAQMGFEILEEFKKASKESFSAEMALVDYVKNSNGARDTVNRWVEQKTKDKIKNLIPEGMFNKDTILCLVNAVYFKGSWMKHFNRNATQSGKFKTTPSQEIQVQFMYQSSEFRYLESSTLGCQIVELPYAGEKLSMVVLLPNEVDGLGKLESSLNKETLQEAMTSLRNSHPEEVEVTLPKFTLTQEFSLGETLKGMGASDLFSPGKADLSGISAAPLVVSEVVHKAFVEVNEEGTIAAAATGVGIMLMSMPMNPV-----FYANHPFLFLIRHNDTGAVLFMGRLVVP 376
BLAST of SERPIN domain-containing protein vs. Ensembl Nematostella
Match: EDO35650 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKW7]) HSP 1 Score: 167.548 bits (423), Expect = 4.846e-48 Identity = 123/368 (33.42%), Postives = 199/368 (54.08%), Query Frame = 3 Query: 120 NIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYK------KSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTS--PTAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEV--PKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGIS--DENLFVDKAIHKTFLDVNEHGIEAAAATA--MSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDP 1181 N FYSP SI A M+ G E+++++ A+ ++ SK++ HKE+S L+ N ++SIAN LF+Q +F I + + QK+Y +++ +++ + A K VN W+E +T KI D+ G FN LTRL L NA+YFK + F+ E++ F ++ V+MM + + + K+LE+P+ + Q+ +L LP + L L + + ++ NS+ ++ + +EV PKFK+ ++ L + + LG++ +FD AD GIS E+LFV +HK F++VNE G EAAAATA M + C M E L F D PFL + H + ++F+GRV +P Sbjct: 16 NTFYSPASICVALGMVYAGARGETADEMATAMHWEGHKPMLPSKHQEHKELSVALN------NPGATNEMSIANNLFLQKDFSILKEFTDICQKYYDADISLVDYKTDFEGARKHVNQWVEERTKKKICDLIAPGVFNMLTRLTLVNAIYFKGMWDKPFKKEHSHSSEFRTTSSNEVEVEMMFQKSKFKYLHSDKYKCKLLELPYVDTQLSMVLVLPDETEGLARFEQDLTHDKMTDIFNSVSSQRPADVEVYIPKFKMTSEFKLNEALQELGMKKMFDQAAADFTGISLPPEHLFVSAVLHKAFVEVNEEGTEAAAATAAIMMMRCAIM-----REPLVFRADHPFLFLIQHCKSKCVLFMGRVMNP 372
BLAST of SERPIN domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000035931.1 (leukocyte elastase inhibitor-like [Source:NCBI gene;Acc:111946638]) HSP 1 Score: 190.66 bits (483), Expect = 3.268e-56 Identity = 124/379 (32.72%), Postives = 207/379 (54.62%), Query Frame = 3 Query: 90 KTVLQENKDGNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFT--SPTAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPT---------QRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISDEN-LFVDKAIHKTFLDVN--EHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDPK 1184 K + ++K N+FYSP SIS+A M++LG +++Q+ ++LK + S++++H +ELL + Y LS+AN LF + ++ + + +K YK+E++K+NF S A +N W+E +T KIKD+ EGS NNLTRLVL NA+YFK N+ F+ + T D F + K TVKMM + ++ ++LE+P+K+ ++ L+FLPT ++ E E +++N +++R + P+FK++ + ++K ++ +G+ D FD ++ D G+S N L + + HK F++VN AA A M + C MP FI D PFL + H S+ +I+F GR P+ Sbjct: 20 KQLSNKDKTANVFYSPFSISSALAMVMLGARGTTASQMTESLKLRDSQDQVHASFAELLGQLNKPKASY---ALSVANRLFGEQTYQFVEEFLGNSRKHYKAELEKVNFMQGSEAARLNINTWVEKQTQGKIKDILAEGSLNNLTRLVLVNAIYFKGNWNKKFDAQETRDADFRLNKNAKKTVKMMYQKSKFPLTYIPEINCQILEMPYKDKELSMLVFLPTDIEDSTTGLEKLEKALTYENFMEWTRPDMMNEVEVR----VGFPRFKMEQKYDMKKVLVSMGMADAFDMSKCDFSGMSPANDLVLSEVFHKAFVEVNEEGTEAAAATAAVMMLRCALMP-------AAFIADHPFLFFIRHNSSMSILFAGRYCSPQ 384
BLAST of SERPIN domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000040134.1 (leukocyte elastase inhibitor-like [Source:NCBI gene;Acc:111946638]) HSP 1 Score: 190.66 bits (483), Expect = 3.268e-56 Identity = 124/379 (32.72%), Postives = 207/379 (54.62%), Query Frame = 3 Query: 90 KTVLQENKDGNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFT--SPTAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPT---------QRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISDEN-LFVDKAIHKTFLDVN--EHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDPK 1184 K + ++K N+FYSP SIS+A M++LG +++Q+ ++LK + S++++H +ELL + Y LS+AN LF + ++ + + +K YK+E++K+NF S A +N W+E +T KIKD+ EGS NNLTRLVL NA+YFK N+ F+ + T D F + K TVKMM + ++ ++LE+P+K+ ++ L+FLPT ++ E E +++N +++R + P+FK++ + ++K ++ +G+ D FD ++ D G+S N L + + HK F++VN AA A M + C MP FI D PFL + H S+ +I+F GR P+ Sbjct: 20 KQLSNKDKTANVFYSPFSISSALAMVMLGARGTTASQMTESLKLRDSQDQVHASFAELLGQLNKPKASY---ALSVANRLFGEQTYQFVEEFLGNSRKHYKAELEKVNFMQGSEAARLNINTWVEKQTQGKIKDILAEGSLNNLTRLVLVNAIYFKGNWNKKFDAQETRDADFRLNKNAKKTVKMMYQKSKFPLTYIPEINCQILEMPYKDKELSMLVFLPTDIEDSTTGLEKLEKALTYENFMEWTRPDMMNEVEVR----VGFPRFKMEQKYDMKKVLVSMGMADAFDMSKCDFSGMSPANDLVLSEVFHKAFVEVNEEGTEAAAATAAVMMLRCALMP-------AAFIADHPFLFFIRHNSSMSILFAGRYCSPQ 384
BLAST of SERPIN domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000036493.1 (pep primary_assembly:ASM223467v1:20:10521870:10567427:1 gene:ENSORLG00000029922.1 transcript:ENSORLT00000036493.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 188.734 bits (478), Expect = 1.431e-55 Identity = 129/379 (34.04%), Postives = 215/379 (56.73%), Query Frame = 3 Query: 90 KTVLQENKDGNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFT--SPTAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPT---------QRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISDEN-LFVDKAIHKTFLDVNEHGIEAAAATA--MSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDPK 1184 K + E+K N+FYSP SIS+A M++LG +++Q+ ++LK + S++++H +ELL + Y LS+AN LF + ++ + + +K YK+E++K+NF S A +N W+E +T KI+D+ EGS NNLTRLVL NA+YFK N+ F+ +NT D F + K TVKMM + + ++ ++LE+P+K+ ++ L+FLPT ++ E E +++ +++R + P+FK++ + ++K ++ +G+ D FD ++ D G+S N L + + HK F++VNE G EAAAATA M + C ++ T FI D PFL + H S+ +I+F GR P+ Sbjct: 20 KQLSNEDKMANVFYSPFSISSALAMVMLGARGTTASQMTESLKLRDSQDQVHASFAELLGQLNKPKASY---ALSVANRLFGEQTYQFVEEFLGNSRKHYKAELEKVNFMQGSEAARLNINTWVEKQTQGKIRDILAEGSLNNLTRLVLVNAIYFKGNWNKKFDAQNTRDADFRLNKNAKKTVKMMYRTSKFPLTYIPEINCQILEMPYKDKELSMLVFLPTDIEDSTTGLEKLEKALTYENFMEWTRPDMMKKVEVR----VGFPRFKMEQKYDMKKVLVSMGMADAFDMSKCDFSGMSPANDLVLSEVFHKAFVEVNEEGTEAAAATAALMMLGCA-----KNFSTDVFIADHPFLFFIRHNSSMSILFAGRYCSPQ 386
BLAST of SERPIN domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000046159.1 (leukocyte elastase inhibitor-like [Source:NCBI gene;Acc:111946699]) HSP 1 Score: 185.267 bits (469), Expect = 1.235e-53 Identity = 129/377 (34.22%), Postives = 212/377 (56.23%), Query Frame = 3 Query: 90 KTVLQENKDGNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFT--SPTAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPT---------QRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISDEN-LFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDPK 1184 K + E+K N+FYSP SIS+A M++LG +++Q+ K+LK + S++++H +ELL + Y LS+AN LF + ++ + + +K YK+E++K+NF S A +N W+E +T KIKD+ EGS NNLTRLVL NA+YFK N+ F+ + T D F + K TVKMM + + ++ ++LE+P+K+ ++ L+FLPT ++ E E +++N +++R + P+FK++ + ++K ++ +G+ D FD ++ D G+S N L + + HK F++VNE G EAAAATA + F + T FI D PFL + H + +I+F GR P+ Sbjct: 78 KQLSNEDKMANVFYSPFSISSALAMVMLGARGTTASQMTKSLKLRDSQDQVHASFAELLGQLNKPKASY---ALSVANRLFGEQTYQFVEEFLGNSRKHYKAELEKVNFMQGSEAARLNINTWVEKQTQGKIKDILAEGSLNNLTRLVLVNAIYFKGNWNKKFDAQETRDADFRLNKNAKKTVKMMYRTSKFPLTYIPEINCQILEMPYKDKELSMLVFLPTDIEDSTTGLEKLEKALTYENFMEWTRPDMMNEVEVR----VGFPRFKMEQKYDMKKVLVSMGMADAFDMSKCDFSGMSPANDLVLSEVFHKAFVEVNEEGTEAAAATAF----IKYGFMLNFSTDVFIADHPFLFFIRHNRSMSILFAGRYCSPQ 443
BLAST of SERPIN domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000037003.1 (leukocyte elastase inhibitor-like [Source:NCBI gene;Acc:111946699]) HSP 1 Score: 182.956 bits (463), Expect = 3.232e-52 Identity = 127/377 (33.69%), Postives = 212/377 (56.23%), Query Frame = 3 Query: 90 KTVLQENKDGNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFT--SPTAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPT---------QRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISDEN-LFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDPK 1184 K + ++K N+FYSP SIS+A M++LG +++Q+ ++LK + S++++H +ELL + Y LS+AN LF + ++ + + +K YK+E++K+NF S A +N W+E +T KIKD+ EGS NNLTRLVL NA+YFK N+ F+ + T D F + K TVKMM + + ++ ++LE+P+K+ ++ L+FLPT ++ E E +++N +++R + P+FK++ + ++K ++ +G+ D FD ++ D G+S N L + + HK F++VNE G EAAAATA + F + T FI D PFL + H + +I+F GR P+ Sbjct: 139 KQLSNKDKTANVFYSPFSISSALAMVMLGARGTTASQMTESLKLRDSQDQVHASFAELLGQLNKPKASY---ALSVANRLFGEQTYQFVEEFLGNSRKHYKAELEKVNFMQGSEAARLNINTWVEKQTQGKIKDILAEGSLNNLTRLVLVNAIYFKGNWNKKFDAQETRDADFRLNKNAKKTVKMMYRTSKFPLTYIPEINCQILEMPYKDKELSMLVFLPTDIEDSTTGLEKLEKALTYENFMEWTRPDMMNEVEVR----VGFPRFKMEQKYDMKKVLVSMGMADAFDMSKCDFSGMSPANDLVLSEVFHKAFVEVNEEGTEAAAATAF----IKYGFMLNFSTDVFIADHPFLFFIRHNRSMSILFAGRYCSPQ 504
BLAST of SERPIN domain-containing protein vs. Planmine SMEST
Match: SMESG000054563.1 (SMESG000054563.1) HSP 1 Score: 678.322 bits (1749), Expect = 0.000e+0 Identity = 364/365 (99.73%), Postives = 365/365 (100.00%), Query Frame = 3 Query: 90 KTVLQENKDGNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTSPTAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISDENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDPK 1184 KTVLQENKDGNIFYSPLSISAAFCMLLLGTND+SSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTSPTAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHKDVKTKLTVKMMKTSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQRFELNSVLNKLKENDLKNLINSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISDENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDPK Sbjct: 15 KTVLQENKDGNIFYSPLSISAAFCMLLLGTNDKSSNQIIKALKYKKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTSPTAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHKDVKTKLTVKMMKTSGDYNFAEDSQLGLKVLEIPFKNYQMRFLLFLPTQRFELNSVLNKLKENDLKNLINSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISDENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRVDDPK 379
BLAST of SERPIN domain-containing protein vs. Planmine SMEST
Match: SMESG000032430.1 (SMESG000032430.1) HSP 1 Score: 167.933 bits (424), Expect = 4.366e-48 Identity = 115/353 (32.58%), Postives = 197/353 (55.81%), Query Frame = 3 Query: 138 LSISAAFCMLLLGTNDESSNQIIKALKYKKSKNE-IHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTS--PTAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFK---NYQMRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVST-LEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKG-ISDENLFVDKAIHKTFLDVNEHGIEAAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGRV 1172 +SI A M L G ++S +++K L + + +E H+++S+ + + V +E DQ + +AN LF++N +++ D+Y + KFY ++K++F S + +++N W+E++TN KIKD+ Q + N+LTRL+L NA+YFK+++K+ F + DK+FH + M+ + Y + ++ LG ++IPFK N F++ LP +R L L + + K + + V + +PKF+I++ LK+ + LG+ F + AD IS L +D +HK F+DV EHG+EAAAATA+ + P + +EFI D PF+ +V K +FIG Sbjct: 1 MSIYMALGMTLYGAKGDTSGEMMKTLHWDQLNSESFHQQLSDCIKTSNV--DEKDQGTIRVANKLFLENKYELLDSYVKAVDKFYNGGIEKMDFQSNPDKSCRDINCWVENQTNGKIKDLLQPNNINSLTRLILVNAIYFKNSWKNEFSVVG--DKTFHLLNGSSKPTTMISKTETYKYLKNPTLGFAAVQIPFKRIHNDDYSFMVVLPLERCSLPKFETVLFQQEWKTVFDDSLFEFVGVHITMPKFRIESSFKLKEELMHLGMVKPFT-DAADFSSMISKPELMIDDVVHKAFIDVTEHGVEAAAATAVMMMLRCAPM-RPIDPIEFICDHPFMFAVV-KQGSLPLFIGHC 346
BLAST of SERPIN domain-containing protein vs. Planmine SMEST
Match: SMESG000032448.1 (SMESG000032448.1) HSP 1 Score: 147.517 bits (371), Expect = 1.741e-40 Identity = 104/348 (29.89%), Postives = 190/348 (54.60%), Query Frame = 3 Query: 153 AFCMLLLGTNDESSNQIIKALKYKKSKNE-IHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTS--PTAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQ---MRFLLFLPTQRFELNSVXXXX-XXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISDE-NLFVDKAIHKTFLDVNEHGIE-AAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGR 1169 A M L G ++S +++K L + + +E H+++S+ + + V +E DQ + +AN LF++N +++ D+Y + KFY ++K++F S + +++N W+E++TN KIKD+ Q + N+LTRL+L NA+YFK ++ F + K FH + + MM Y + DS LG ++IPF+N + + LP L + + + + L + L + + +PKF+I+ +LK + LG+ F + AD +++E +L +D +HK F+D++E+G+E AAA M + CM + ++ +EF D PF+ ++ K +FIG+ Sbjct: 2 ALGMTLYGAKGDTSGEMMKTLHWDQLNSESFHQQLSDCIKTSNV--DEKDQGTIRVANKLFLENKYELLDSYVKAVDKFYNGGIEKMDFQSNPDKSCRDINCWVENQTNGKIKDLLQPNNINSLTRLILVNAIYFKGAWEKTFSV--CGQKPFHLINGSVKSTNMMDNVEQYRYLNDSSLGFSAVQIPFRNIKDDHYSLFVILPKAPKTLPELEGLIFQHSWKSILSDELFQNKRVRITMPKFRIECSFSLKKKLQNLGMVKPF-TSSADFSLMTNELDLMLDDVVHKAFIDIDENGVEAAAATAVMMVECMMI--IREDDPIEFKCDRPFMFALV-KQGSLPLFIGQ 341
BLAST of SERPIN domain-containing protein vs. Planmine SMEST
Match: SMESG000032440.1 (SMESG000032440.1) HSP 1 Score: 147.517 bits (371), Expect = 1.741e-40 Identity = 104/348 (29.89%), Postives = 190/348 (54.60%), Query Frame = 3 Query: 153 AFCMLLLGTNDESSNQIIKALKYKKSKNE-IHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTS--PTAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQ---MRFLLFLPTQRFELNSVXXXX-XXXXXXXXXXSLKLRQVSTLEVPKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGISDE-NLFVDKAIHKTFLDVNEHGIE-AAAATAMSICCMSMPFYESNETLEFIVDEPFLLSVYHKSADAIVFIGR 1169 A M L G ++S +++K L + + +E H+++S+ + + V +E DQ + +AN LF++N +++ D+Y + KFY ++K++F S + +++N W+E++TN KIKD+ Q + N+LTRL+L NA+YFK ++ F + K FH + + MM Y + DS LG ++IPF+N + + LP L + + + + L + L + + +PKF+I+ +LK + LG+ F + AD +++E +L +D +HK F+D++E+G+E AAA M + CM + ++ +EF D PF+ ++ K +FIG+ Sbjct: 2 ALGMTLYGAKGDTSGEMMKTLHWDQLNSESFHQQLSDCIKTSNV--DEKDQGTIRVANKLFLENKYELLDSYVKAVDKFYNGGIEKMDFQSNPDKSCRDINCWVENQTNGKIKDLLQPNNINSLTRLILVNAIYFKGAWEKTFSV--CGQKPFHLINGSVKSTNMMDNVEQYRYLNDSSLGFSAVQIPFRNIKDDHYSLFVILPKAPKTLPELEGLIFQHSWKSILSDELFQNKRVRITMPKFRIECSFSLKKKLQNLGMVKPF-TSSADFSLMTNELDLMLDDVVHKAFIDIDENGVEAAAATAVMMVECMMI--IREDDPIEFKCDRPFMFALV-KQGSLPLFIGQ 341
BLAST of SERPIN domain-containing protein vs. Planmine SMEST
Match: SMESG000032457.1 (SMESG000032457.1) HSP 1 Score: 148.288 bits (373), Expect = 2.055e-40 Identity = 109/357 (30.53%), Postives = 201/357 (56.30%), Query Frame = 3 Query: 90 KTVLQENKDGNIFYSPLSISAAFCMLLLGTNDESSNQIIKALKY-KKSKNEIHKEISELLDKTAVIMNEYDQTQLSIANGLFMQNNFKIKDNYQNELQKFYKSEMKKINFTS--PTAIKEVNGWIESKTNDKIKDMFQEGSFNNLTRLVLANAVYFKSNFKDGFEIENTVDKSFHXXXXXXXXXXXXXXSGDYNFAEDSQLGLKVLEIPFKNYQ---MRFLLFLPTQRFELNSVXXXXXXXXXXXXXXSLKLRQVSTLEV--PKFKIDTQLNLKDLMGLLGVQDIFDPNRADLKGIS-DENLFVDKAIHKTFLDVNEHGIEA---AAATAMSICCMSMPFYESNETLEFIVDEPFLL 1124 ++++ +N D NI +SP+SI A M L G E+ +++ K+L + +++ N H+++ +++ KT I + + T + IAN LF++ + + D Y L Y S++K+++F + A +++N W+E++TN KIK++ Q+ NN T+L+L NA+YF + F++ K F+ T +++M+ S +++ ++ L ++IPFK + F++ LP +R L V + +++ + N L +EV PKFKI+ +L D + LG+ F P+ AD G++ +++L ++ +HK F+DV+E+GIEA A T M C M+ P + +EF D PF+ Sbjct: 14 QSIINDNYDKNIIFSPISIYLALGMTLWGAQGETLSEMSKSLYWNQENCNLYHQQLHDVI-KTCNIESSPNGT-VKIANKLFLETKYNLIDTYVKSLSCLYDSKIKQLDFENHPEQACQDINNWVENETNGKIKNLLQQRQINNQTKLILVNAIYFNGAWLKQFKV--IGHKQFYLLNGTSKSIEMISNSEHFSYLKNDSLKFSAVKIPFKIMESILFSFMIILPDERDSLAKVEQDIFQSNWETTFND-DLFTAKNVEVIMPKFKIENSFSLSDELKKLGMLKPFSPD-ADFSGMTGNKDLMINDVVHKAFIDVDENGIEAAAATAVTMMLGCAMTQP----QQPIEFKCDHPFMF 360 The following BLAST results are available for this feature:
BLAST of SERPIN domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of SERPIN domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of SERPIN domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of SERPIN domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of SERPIN domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of SERPIN domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of SERPIN domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of SERPIN domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of SERPIN domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of SERPIN domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of SERPIN domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of SERPIN domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 3
BLAST of SERPIN domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of SERPIN domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30021146 ID=SMED30021146|Name=SERPIN domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1241bpback to top protein sequence of SMED30021146-orf-1 >SMED30021146-orf-1 ID=SMED30021146-orf-1|Name=SMED30021146-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=380bp MASESLESFSIEFLKTVLQENKDGNIFYSPLSISAAFCMLLLGTNDESSNback to top Annotated Terms
The following terms have been associated with this transcript:
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