POU domain protein

Overview


Name	POU domain protein
Smed ID	SMED30021108
Length (bp)	1667

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of POU domain protein (SMED30021108) t-SNE clustered cells

Violin plots show distribution of expression levels for POU domain protein (SMED30021108) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of POU domain protein (SMED30021108) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for POU domain protein (SMED30021108) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30021108

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 7

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
nervous system	SMED30021108	SMESG000008858.1	dd_Smed_v4_38342_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30021108	SMESG000008858.1	dd_Smed_v4_38342_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30021108	SMESG000008858.1	dd_Smed_v4_38342_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30021108	SMESG000008858.1	Contig35971	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30021108	SMESG000008858.1	Contig35971	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
reproductive organ	SMED30021108	SMESG000008858.1	Contig35971	newmark_ests	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30021108	SMESG000008858.1	Contig35971	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of POU domain protein vs. Ensembl Human
Match: POU3F4 (POU class 3 homeobox 4 [Source:HGNC Symbol;Acc:HGNC:9217])

HSP 1 Score: 214.927 bits (546), Expect = 5.225e-64
Identity = 101/140 (72.14%), Postives = 120/140 (85.71%), Query Frame = 1

Query: 1030 ELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            ELEQFAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL+KWLEEAD S + +  +++K+A Q R+RKKRT+IE++ K +LE+ F K PKP A  I SL++ + ++KEVVRVWFCNRRQ
Sbjct:  193 ELEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEAD-SSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGVLETHFLKCPKPAAQEISSLADSLQLEKEVVRVWFCNRRQ 331

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BLAST of POU domain protein vs. Ensembl Human
Match: POU3F2 (POU class 3 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:9215])

HSP 1 Score: 216.083 bits (549), Expect = 1.798e-63
Identity = 102/140 (72.86%), Postives = 120/140 (85.71%), Query Frame = 1

Query: 1030 ELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            +LEQFAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL+KWLEEAD S S +  +++K+A Q R+RKKRT+IE++ K  LES F K PKP+A  I SL++ + ++KEVVRVWFCNRRQ
Sbjct:  269 DLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEAD-SSSGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITSLADSLQLEKEVVRVWFCNRRQ 407

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BLAST of POU domain protein vs. Ensembl Human
Match: POU3F1 (POU class 3 homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9214])

HSP 1 Score: 212.616 bits (540), Expect = 3.916e-62
Identity = 101/140 (72.14%), Postives = 117/140 (83.57%), Query Frame = 1

Query: 1030 ELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            +LEQFAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL+KWLEE D S S +  N++K+A Q R+RKKRT+IE+  K  LES F K PKP+A  I  L++ + ++KEVVRVWFCNRRQ
Sbjct:  254 DLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEETD-SSSGSPTNLDKIAAQGRKRKKRTSIEVGVKGALESHFLKCPKPSAHEITGLADSLQLEKEVVRVWFCNRRQ 392

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BLAST of POU domain protein vs. Ensembl Human
Match: POU3F3 (POU class 3 homeobox 3 [Source:HGNC Symbol;Acc:HGNC:9216])

HSP 1 Score: 213.001 bits (541), Expect = 9.900e-62
Identity = 100/140 (71.43%), Postives = 120/140 (85.71%), Query Frame = 1

Query: 1030 ELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            +LEQFAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL+KWLEEAD S + +  +++K+A Q R+RKKRT+IE++ K  LES F K PKP+A  I +L++ + ++KEVVRVWFCNRRQ
Sbjct:  321 DLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEAD-SSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITNLADSLQLEKEVVRVWFCNRRQ 459

[Close]

Query: 1030 ELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            +LEQFAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL+KWLEEAD S + +  +++K+A Q R+RKKRT+IE++ K  LES F K PKP+A  I +L++ + ++KEVVRVWFCNRRQ
Sbjct:  321 DLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEAD-SSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITNLADSLQLEKEVVRVWFCNRRQ 459

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BLAST of POU domain protein vs. Ensembl Celegans
Match: ceh-6 (Homeobox protein ceh-6 [Source:UniProtKB/Swiss-Prot;Acc:P20268])

HSP 1 Score: 195.667 bits (496), Expect = 5.340e-57
Identity = 104/185 (56.22%), Postives = 130/185 (70.27%), Query Frame = 1

Query:  898 PTAFSYQSSNSMSLLGSQQPEISKDLFLSDSIIENSKLSTMDCRELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQ-NRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            P A+ +   +S S+ G+  P       LSD I ++S+ +  D  +LE FAK FKQRRIKLG+TQADVG+ALGTLYGN+FSQTTICRFEALQLSFKNM KL+PLL KWLEEAD +  +     EK+  Q  R+RKKRT+IE+N K  LE  F  + KP A  I  ++  + ++KEVVRVWFCNRRQ
Sbjct:  157 PPAYQFSCDDSGSVSGAGGPHQP----LSD-ISDDSEQTCPD--DLEGFAKQFKQRRIKLGYTQADVGVALGTLYGNIFSQTTICRFEALQLSFKNMCKLKPLLFKWLEEADSTTGSPNSTFEKMTGQAGRKRKKRTSIEVNVKSRLEFHFQSNQKPNAQEITQVAMELQLEKEVVRVWFCNRRQ 334

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BLAST of POU domain protein vs. Ensembl Celegans
Match: ceh-18 (Homeobox protein ceh-18 [Source:UniProtKB/Swiss-Prot;Acc:P41934])

HSP 1 Score: 150.214 bits (378), Expect = 6.562e-39
Identity = 83/202 (41.09%), Postives = 118/202 (58.42%), Query Frame = 1

Query:  967 KDLFLSDSIIENSKLST---MDCRELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADL---------------------------------SLSNTVVNVEKLANQNRQ-----RKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            + LF   S IE + +S    +D  ELE FA+TFK++RIK GFTQ DVG+ALG  YG  FSQTTI RFEAL LSFKNM KLRPLL +WL + ++                                 S+SN++ +V   +  +R+     R+KRTN++MN ++ L++ F  +P+P    +  ++  + +D++VVRVWFCNRRQ
Sbjct:  273 RRLFDDTSRIEAASMSGDDRIDMNELEAFAQTFKKQRIKFGFTQGDVGVALGKRYGTDFSQTTISRFEALNLSFKNMCKLRPLLKEWLADVEMAIEGGATVTDLIDKKTIHNGNHHTIHHVDIHETSISNSISSVTASSLLSREQHVKRRRKRTNLDMNQRNALDTFFALNPRPDHDKMTDIANSLELDRDVVRVWFCNRRQ 474

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BLAST of POU domain protein vs. Ensembl Celegans
Match: ceh-18 (Homeobox protein ceh-18 [Source:UniProtKB/Swiss-Prot;Acc:P41934])

HSP 1 Score: 149.828 bits (377), Expect = 7.853e-39
Identity = 83/202 (41.09%), Postives = 118/202 (58.42%), Query Frame = 1

Query:  967 KDLFLSDSIIENSKLST---MDCRELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADL---------------------------------SLSNTVVNVEKLANQNRQ-----RKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            + LF   S IE + +S    +D  ELE FA+TFK++RIK GFTQ DVG+ALG  YG  FSQTTI RFEAL LSFKNM KLRPLL +WL + ++                                 S+SN++ +V   +  +R+     R+KRTN++MN ++ L++ F  +P+P    +  ++  + +D++VVRVWFCNRRQ
Sbjct:  271 RRLFDDTSRIEAASMSGDDRIDMNELEAFAQTFKKQRIKFGFTQGDVGVALGKRYGTDFSQTTISRFEALNLSFKNMCKLRPLLKEWLADVEMAIEGGATVTDLIDKKTIHNGNHHTIHHVDIHETSISNSISSVTASSLLSREQHVKRRRKRTNLDMNQRNALDTFFALNPRPDHDKMTDIANSLELDRDVVRVWFCNRRQ 472

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BLAST of POU domain protein vs. Ensembl Celegans
Match: unc-86 (Transcription factor unc-86 [Source:UniProtKB/Swiss-Prot;Acc:P13528])

HSP 1 Score: 136.732 bits (343), Expect = 4.484e-36
Identity = 70/149 (46.98%), Postives = 100/149 (67.11%), Query Frame = 1

Query: 1021 DCRELEQFAKTFKQRRIKLGFTQADVGLALGTL----YGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLS--NTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            D R+LE FA+ FKQRRIKLG TQADVG AL  L     G++ SQ+TICRFE+L LS  NM  L+P+L  WLE+A+ ++   +T+ ++  +     +++KRT+I    K  LE  F + P+P+   I S+++R+ + K VVRVWFCN+RQ
Sbjct:  103 DPRQLETFAEHFKQRRIKLGVTQADVGKALAHLKMPGVGSL-SQSTICRFESLTLSHNNMVALKPILHSWLEKAEEAMKQKDTIGDINGILPNTDKKRKRTSIAAPEKRELEQFFKQQPRPSGERIASIADRLDLKKNVVRVWFCNQRQ 250

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BLAST of POU domain protein vs. Ensembl Celegans
Match: unc-86 (Transcription factor unc-86 [Source:UniProtKB/Swiss-Prot;Acc:P13528])

HSP 1 Score: 137.117 bits (344), Expect = 1.481e-35
Identity = 70/149 (46.98%), Postives = 100/149 (67.11%), Query Frame = 1

Query: 1021 DCRELEQFAKTFKQRRIKLGFTQADVGLALGTL----YGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLS--NTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            D R+LE FA+ FKQRRIKLG TQADVG AL  L     G++ SQ+TICRFE+L LS  NM  L+P+L  WLE+A+ ++   +T+ ++  +     +++KRT+I    K  LE  F + P+P+   I S+++R+ + K VVRVWFCN+RQ
Sbjct:  159 DPRQLETFAEHFKQRRIKLGVTQADVGKALAHLKMPGVGSL-SQSTICRFESLTLSHNNMVALKPILHSWLEKAEEAMKQKDTIGDINGILPNTDKKRKRTSIAAPEKRELEQFFKQQPRPSGERIASIADRLDLKKNVVRVWFCNQRQ 306

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BLAST of POU domain protein vs. Ensembl Fly
Match: vvl (gene:FBgn0086680 transcript:FBtr0345911)

HSP 1 Score: 217.238 bits (552), Expect = 1.818e-64
Identity = 101/152 (66.45%), Postives = 121/152 (79.61%), Query Frame = 1

Query:  994 IENSKLSTMDCRELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            I   +  T    +LE FAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL KWLEEAD S + +  +++K+A Q R+RKKRT+IE++ K  LE  F+K PKP+A  I SL++ + ++KEVVRVWFCNRRQ
Sbjct:  207 ISGGEEDTPTSDDLEAFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLQKWLEEAD-STTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALEQHFHKQPKPSAQEITSLADSLQLEKEVVRVWFCNRRQ 357

[Close]

BLAST of POU domain protein vs. Ensembl Fly
Match: vvl (gene:FBgn0086680 transcript:FBtr0076944)

HSP 1 Score: 217.238 bits (552), Expect = 1.818e-64
Identity = 101/152 (66.45%), Postives = 121/152 (79.61%), Query Frame = 1

Query:  994 IENSKLSTMDCRELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            I   +  T    +LE FAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL KWLEEAD S + +  +++K+A Q R+RKKRT+IE++ K  LE  F+K PKP+A  I SL++ + ++KEVVRVWFCNRRQ
Sbjct:  207 ISGGEEDTPTSDDLEAFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLQKWLEEAD-STTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALEQHFHKQPKPSAQEITSLADSLQLEKEVVRVWFCNRRQ 357

[Close]

BLAST of POU domain protein vs. Ensembl Fly
Match: vvl (gene:FBgn0086680 transcript:FBtr0330059)

HSP 1 Score: 218.394 bits (555), Expect = 2.407e-62
Identity = 101/152 (66.45%), Postives = 121/152 (79.61%), Query Frame = 1

Query:  994 IENSKLSTMDCRELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            I   +  T    +LE FAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL KWLEEAD S + +  +++K+A Q R+RKKRT+IE++ K  LE  F+K PKP+A  I SL++ + ++KEVVRVWFCNRRQ
Sbjct:  207 ISGGEEDTPTSDDLEAFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLQKWLEEAD-STTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALEQHFHKQPKPSAQEITSLADSLQLEKEVVRVWFCNRRQ 357

[Close]

BLAST of POU domain protein vs. Ensembl Fly
Match: vvl (gene:FBgn0086680 transcript:FBtr0346998)

HSP 1 Score: 218.009 bits (554), Expect = 3.465e-62
Identity = 101/152 (66.45%), Postives = 121/152 (79.61%), Query Frame = 1

Query:  994 IENSKLSTMDCRELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            I   +  T    +LE FAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL KWLEEAD S + +  +++K+A Q R+RKKRT+IE++ K  LE  F+K PKP+A  I SL++ + ++KEVVRVWFCNRRQ
Sbjct:  207 ISGGEEDTPTSDDLEAFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLQKWLEEAD-STTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALEQHFHKQPKPSAQEITSLADSLQLEKEVVRVWFCNRRQ 357

[Close]

BLAST of POU domain protein vs. Ensembl Fly
Match: vvl (gene:FBgn0086680 transcript:FBtr0346999)

HSP 1 Score: 218.009 bits (554), Expect = 4.814e-62
Identity = 101/152 (66.45%), Postives = 121/152 (79.61%), Query Frame = 1

Query:  994 IENSKLSTMDCRELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            I   +  T    +LE FAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL KWLEEAD S + +  +++K+A Q R+RKKRT+IE++ K  LE  F+K PKP+A  I SL++ + ++KEVVRVWFCNRRQ
Sbjct:  207 ISGGEEDTPTSDDLEAFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLQKWLEEAD-STTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALEQHFHKQPKPSAQEITSLADSLQLEKEVVRVWFCNRRQ 357

[Close]

BLAST of POU domain protein vs. Ensembl Zebrafish
Match: pou3f2a (POU class 3 homeobox 2a [Source:ZFIN;Acc:ZDB-GENE-980526-139])

HSP 1 Score: 215.312 bits (547), Expect = 1.271e-64
Identity = 102/140 (72.86%), Postives = 120/140 (85.71%), Query Frame = 1

Query: 1030 ELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            +LEQFAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL+KWLEEAD S S +  +++K+A Q R+RKKRT+IE++ K  LES F K PKP A+ I SL++ + ++KEVVRVWFCNRRQ
Sbjct:  166 DLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEAD-STSGSPTSLDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPGASEINSLADSLQLEKEVVRVWFCNRRQ 304

[Close]

BLAST of POU domain protein vs. Ensembl Zebrafish
Match: pou3f2b (POU class 3 homeobox 2b [Source:NCBI gene;Acc:30397])

HSP 1 Score: 216.083 bits (549), Expect = 2.146e-64
Identity = 102/140 (72.86%), Postives = 120/140 (85.71%), Query Frame = 1

Query: 1030 ELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            +LEQFAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL+KWLEEAD S S +  +++K+A Q R+RKKRT+IE++ K  LES F K PKP A+ I SL++ + ++KEVVRVWFCNRRQ
Sbjct:  207 DLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEAD-STSGSPTSLDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPAASEITSLADSLQLEKEVVRVWFCNRRQ 345

[Close]

Query: 1030 ELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            +LEQFAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL+KWLEEAD S S +  +++K+A Q R+RKKRT+IE++ K  LES F K PKP A+ I SL++ + ++KEVVRVWFCNRRQ
Sbjct:  207 DLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEAD-STSGSPTSLDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPAASEITSLADSLQLEKEVVRVWFCNRRQ 345

[Close]

BLAST of POU domain protein vs. Ensembl Zebrafish
Match: pou3f3a (POU class 3 homeobox 3a [Source:NCBI gene;Acc:30386])

HSP 1 Score: 215.312 bits (547), Expect = 1.461e-63
Identity = 101/140 (72.14%), Postives = 120/140 (85.71%), Query Frame = 1

Query: 1030 ELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            +LEQFAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL+KWLEEAD S + +  +++K+A Q R+RKKRT+IE++ K  LES F K PKP+A  I SL++ + ++KEVVRVWFCNRRQ
Sbjct:  249 DLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEAD-STTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITSLADNLQLEKEVVRVWFCNRRQ 387

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BLAST of POU domain protein vs. Ensembl Zebrafish
Match: pou3f3a (POU class 3 homeobox 3a [Source:NCBI gene;Acc:30386])

HSP 1 Score: 215.312 bits (547), Expect = 2.167e-63
Identity = 101/140 (72.14%), Postives = 120/140 (85.71%), Query Frame = 1

Query: 1030 ELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            +LEQFAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL+KWLEEAD S + +  +++K+A Q R+RKKRT+IE++ K  LES F K PKP+A  I SL++ + ++KEVVRVWFCNRRQ
Sbjct:  249 DLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEAD-STTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITSLADNLQLEKEVVRVWFCNRRQ 387

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BLAST of POU domain protein vs. Ensembl Xenopus
Match: pou3f2 (POU class 3 homeobox 2 [Source:NCBI gene;Acc:100486226])

HSP 1 Score: 216.083 bits (549), Expect = 2.911e-64
Identity = 102/140 (72.86%), Postives = 120/140 (85.71%), Query Frame = 1

Query: 1030 ELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            +LEQFAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL+KWLEEAD S S +  +++K+A Q R+RKKRT+IE++ K  LES F K PKP+A  I SL++ + ++KEVVRVWFCNRRQ
Sbjct:  208 DLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEAD-SSSGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITSLADSLQLEKEVVRVWFCNRRQ 346

[Close]

BLAST of POU domain protein vs. Ensembl Xenopus
Match: pou3f4 (POU class 3 homeobox 4 [Source:NCBI gene;Acc:100036711])

HSP 1 Score: 214.157 bits (544), Expect = 9.525e-64
Identity = 101/140 (72.14%), Postives = 120/140 (85.71%), Query Frame = 1

Query: 1030 ELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            ELEQFAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL+KWLEEAD S + +  +++K+A Q R+RKKRT+IE++ K +LE+ F K PKP A  I SL++ + ++KEVVRVWFCNRRQ
Sbjct:  192 ELEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEAD-SSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGVLETHFLKCPKPAAQEISSLADSLQLEKEVVRVWFCNRRQ 330

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BLAST of POU domain protein vs. Ensembl Xenopus
Match: tecta.1 (tectorin alpha, gene 1 [Source:Xenbase;Acc:XB-GENE-1011878])

HSP 1 Score: 212.616 bits (540), Expect = 5.186e-63
Identity = 100/140 (71.43%), Postives = 118/140 (84.29%), Query Frame = 1

Query: 1030 ELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            +LEQFAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL+KWLEE D S + +  N++K+A Q R+RKKRT+IE+  K  LE+ F K PKP+A  I SL++ + ++KEVVRVWFCNRRQ
Sbjct:  201 DLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEETD-STTGSPTNLDKIAAQGRKRKKRTSIEVGVKGALENHFLKCPKPSAHEITSLADSLQLEKEVVRVWFCNRRQ 339

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BLAST of POU domain protein vs. Ensembl Xenopus
Match: slc25a38 (solute carrier family 25 member 38 [Source:Xenbase;Acc:XB-GENE-5814283])

HSP 1 Score: 214.157 bits (544), Expect = 9.324e-63
Identity = 100/140 (71.43%), Postives = 120/140 (85.71%), Query Frame = 1

Query: 1030 ELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            +LEQFAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL+KWLEEAD S + +  +++K+A Q R+RKKRT+IE++ K  LES F K PKP+A  I +L++ + ++KEVVRVWFCNRRQ
Sbjct:  269 DLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEAD-SSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITNLADSLQLEKEVVRVWFCNRRQ 407

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BLAST of POU domain protein vs. Ensembl Xenopus
Match: efl1 (elongation factor like GTPase 1 [Source:Xenbase;Acc:XB-GENE-5894854])

HSP 1 Score: 188.734 bits (478), Expect = 6.995e-52
Identity = 95/151 (62.91%), Postives = 114/151 (75.50%), Query Frame = 1

Query: 1021 DCRELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEA-----DLSLSN-TVVNV--EKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            D  ELEQFAKTFKQRRIKLGFTQ DVGLA+G LYGN FSQTTI RFEAL LSFKNM KL+PLL KWL +A     D SLSN +V+N     +   NR+RKKRT+IE N +  LE SF ++ KPT+  I  +++++ M+KEV+RVWFCNRRQ
Sbjct:  284 DLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAENITSDSSLSNQSVLNSPGHGMEGLNRRRKKRTSIETNIRVALEKSFLENQKPTSEEITMIADQLNMEKEVIRVWFCNRRQ 434

[Close]

BLAST of POU domain protein vs. Ensembl Mouse
Match: Pou3f4 (POU domain, class 3, transcription factor 4 [Source:MGI Symbol;Acc:MGI:101894])

HSP 1 Score: 214.927 bits (546), Expect = 3.332e-64
Identity = 101/140 (72.14%), Postives = 120/140 (85.71%), Query Frame = 1

Query: 1030 ELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            ELEQFAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL+KWLEEAD S + +  +++K+A Q R+RKKRT+IE++ K +LE+ F K PKP A  I SL++ + ++KEVVRVWFCNRRQ
Sbjct:  193 ELEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEAD-SSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGVLETHFLKCPKPAAQEISSLADSLQLEKEVVRVWFCNRRQ 331

[Close]

BLAST of POU domain protein vs. Ensembl Mouse
Match: Pou3f2 (POU domain, class 3, transcription factor 2 [Source:MGI Symbol;Acc:MGI:101895])

HSP 1 Score: 216.083 bits (549), Expect = 1.297e-63
Identity = 102/140 (72.86%), Postives = 120/140 (85.71%), Query Frame = 1

Query: 1030 ELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            +LEQFAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL+KWLEEAD S S +  +++K+A Q R+RKKRT+IE++ K  LES F K PKP+A  I SL++ + ++KEVVRVWFCNRRQ
Sbjct:  271 DLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEAD-SSSGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITSLADSLQLEKEVVRVWFCNRRQ 409

[Close]

BLAST of POU domain protein vs. Ensembl Mouse
Match: Pou3f1 (POU domain, class 3, transcription factor 1 [Source:MGI Symbol;Acc:MGI:101896])

HSP 1 Score: 213.001 bits (541), Expect = 2.144e-62
Identity = 101/140 (72.14%), Postives = 117/140 (83.57%), Query Frame = 1

Query: 1030 ELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            +LEQFAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL+KWLEE D S S +  N++K+A Q R+RKKRT+IE+  K  LES F K PKP+A  I  L++ + ++KEVVRVWFCNRRQ
Sbjct:  252 DLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEETD-SSSGSPTNLDKIAAQGRKRKKRTSIEVGVKGALESHFLKCPKPSAHEITGLADSLQLEKEVVRVWFCNRRQ 390

[Close]

BLAST of POU domain protein vs. Ensembl Mouse
Match: Pou3f3 (POU domain, class 3, transcription factor 3 [Source:MGI Symbol;Acc:MGI:102564])

HSP 1 Score: 212.616 bits (540), Expect = 6.976e-62
Identity = 100/140 (71.43%), Postives = 120/140 (85.71%), Query Frame = 1

Query: 1030 ELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            +LEQFAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL+KWLEEAD S + +  +++K+A Q R+RKKRT+IE++ K  LES F K PKP+A  I +L++ + ++KEVVRVWFCNRRQ
Sbjct:  318 DLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEAD-SSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITNLADSLQLEKEVVRVWFCNRRQ 456

[Close]

Query: 1030 ELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            +LEQFAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL+KWLEEAD S + +  +++K+A Q R+RKKRT+IE++ K  LES F K PKP+A  I +L++ + ++KEVVRVWFCNRRQ
Sbjct:  318 DLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEAD-SSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITNLADSLQLEKEVVRVWFCNRRQ 456

[Close]

BLAST of POU domain protein vs. UniProt/SwissProt
Match: sp|P31364|P3F4A_XENLA (POU domain, class 3, transcription factor 4-A OS=Xenopus laevis OX=8355 GN=pou3f4-a PE=2 SV=2)

HSP 1 Score: 215.698 bits (548), Expect = 1.377e-63
Identity = 102/140 (72.86%), Postives = 119/140 (85.00%), Query Frame = 1

Query: 1030 ELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            ELEQFAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL+KWLEEAD S  N   +++K+A Q R+RKKRT+IE++ K +LE+ F K PKP A  I SL++ + ++KEVVRVWFCNRRQ
Sbjct:  193 ELEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEADSSTGNP-TSIDKIAAQGRKRKKRTSIEVSVKGVLETHFLKCPKPAALEITSLADSLQLEKEVVRVWFCNRRQ 331

[Close]

BLAST of POU domain protein vs. UniProt/SwissProt
Match: sp|P79746|PO3F2_DANRE (POU domain, class 3, transcription factor 2 OS=Danio rerio OX=7955 GN=pou3f2 PE=1 SV=1)

HSP 1 Score: 216.083 bits (549), Expect = 1.620e-63
Identity = 102/140 (72.86%), Postives = 120/140 (85.71%), Query Frame = 1

Query: 1030 ELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            +LEQFAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL+KWLEEAD S S +  +++K+A Q R+RKKRT+IE++ K  LES F K PKP A+ I SL++ + ++KEVVRVWFCNRRQ
Sbjct:  207 DLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEAD-STSGSPTSLDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPAASEITSLADSLQLEKEVVRVWFCNRRQ 345

[Close]

BLAST of POU domain protein vs. UniProt/SwissProt
Match: sp|P16241|CF1A_DROME (POU domain protein CF1A OS=Drosophila melanogaster OX=7227 GN=vvl PE=2 SV=5)

HSP 1 Score: 217.238 bits (552), Expect = 1.822e-63
Identity = 101/152 (66.45%), Postives = 121/152 (79.61%), Query Frame = 1

Query:  994 IENSKLSTMDCRELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            I   +  T    +LE FAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL KWLEEAD S + +  +++K+A Q R+RKKRT+IE++ K  LE  F+K PKP+A  I SL++ + ++KEVVRVWFCNRRQ
Sbjct:  207 ISGGEEDTPTSDDLEAFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLQKWLEEAD-STTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALEQHFHKQPKPSAQEITSLADSLQLEKEVVRVWFCNRRQ 357

[Close]

BLAST of POU domain protein vs. UniProt/SwissProt
Match: sp|P62516|PO3F4_RAT (POU domain, class 3, transcription factor 4 OS=Rattus norvegicus OX=10116 GN=Pou3f4 PE=2 SV=1)

HSP 1 Score: 214.927 bits (546), Expect = 2.331e-63
Identity = 101/140 (72.14%), Postives = 120/140 (85.71%), Query Frame = 1

Query: 1030 ELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            ELEQFAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL+KWLEEAD S + +  +++K+A Q R+RKKRT+IE++ K +LE+ F K PKP A  I SL++ + ++KEVVRVWFCNRRQ
Sbjct:  193 ELEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEAD-SSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGVLETHFLKCPKPAAQEISSLADSLQLEKEVVRVWFCNRRQ 331

[Close]

BLAST of POU domain protein vs. UniProt/SwissProt
Match: sp|P62515|PO3F4_MOUSE (POU domain, class 3, transcription factor 4 OS=Mus musculus OX=10090 GN=Pou3f4 PE=2 SV=1)

HSP 1 Score: 214.927 bits (546), Expect = 2.331e-63
Identity = 101/140 (72.14%), Postives = 120/140 (85.71%), Query Frame = 1

Query: 1030 ELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            ELEQFAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL+KWLEEAD S + +  +++K+A Q R+RKKRT+IE++ K +LE+ F K PKP A  I SL++ + ++KEVVRVWFCNRRQ
Sbjct:  193 ELEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEAD-SSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGVLETHFLKCPKPAAQEISSLADSLQLEKEVVRVWFCNRRQ 331

[Close]

BLAST of POU domain protein vs. TrEMBL
Match: Q23958 (DjPOU2 protein (Fragment) OS=Dugesia japonica OX=6161 GN=DjPOU2 PE=3 SV=1)

HSP 1 Score: 224.942 bits (572), Expect = 3.741e-68
Identity = 108/113 (95.58%), Postives = 111/113 (98.23%), Query Frame = 1

Query: 1081 FTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEV 1419
            FTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKL NQ+RQRKKRTNIEMNTKDILE+SFNKDPKPTAAHI SL+ERILMDKEV
Sbjct:    1 FTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLTNQSRQRKKRTNIEMNTKDILETSFNKDPKPTAAHITSLAERILMDKEV 113

[Close]

BLAST of POU domain protein vs. TrEMBL
Match: A0A1Y3BV66 (POU domain protein OS=Euroglyphus maynei OX=6958 GN=BLA29_006121 PE=3 SV=1)

HSP 1 Score: 223.787 bits (569), Expect = 9.765e-65
Identity = 114/182 (62.64%), Postives = 139/182 (76.37%), Query Frame = 1

Query:  916 QSSNSMSLLGSQQPEI----SKDLFLSDSIIENSKLSTMDCRELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            +SS SM LLGS    I    S  +  ++S  E    S+ D   LEQFAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL+KWLEEAD S + +  +++K+A Q R+RKKRT+IE++ K  LE+ F+K PKP+A  I +L+E + ++KEVVRVWFCNRRQ
Sbjct:   26 KSSFSMGLLGSSDSSIPRVHSGSVTGTESAGEEETPSSDD---LEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLAKWLEEAD-STTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALETHFHKQPKPSAQEITTLAEHLQLEKEVVRVWFCNRRQ 203

[Close]

BLAST of POU domain protein vs. TrEMBL
Match: A0A3S3PLI0 (POU domain protein OS=Dinothrombium tinctorium OX=1965070 GN=B4U79_00154 PE=3 SV=1)

HSP 1 Score: 224.172 bits (570), Expect = 8.548e-64
Identity = 112/183 (61.20%), Postives = 134/183 (73.22%), Query Frame = 1

Query:  904 AFSYQSSNSMSLLGSQQPEISKDLFLSDSIIENS-KLSTMDCRELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            A    S   +S LG      S  L       ENS +  T    +LEQFAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL+KWLEEAD S + +  +++K+A Q R+RKKRT+IE++ K  LE+ F+K PKP+A  I SL+E + ++KEVVRVWFCNRRQ
Sbjct:  177 AMRSDSLGGLSELGHGHDRGSVGLHADHRHHENSGEEETPSSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLAKWLEEAD-STTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALENHFHKQPKPSAQEIASLAETLQLEKEVVRVWFCNRRQ 358

[Close]

BLAST of POU domain protein vs. TrEMBL
Match: B7Q3J4 (POU domain protein OS=Ixodes scapularis OX=6945 GN=8035365 PE=3 SV=1)

HSP 1 Score: 223.402 bits (568), Expect = 1.652e-63
Identity = 108/170 (63.53%), Postives = 131/170 (77.06%), Query Frame = 1

Query:  940 LGSQQPEISKDLFLSDSIIENSKLSTMDCRELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            +G Q P        S+S  E +  S     +LEQFAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL+KWLEEAD S + +  +++K+A Q R+RKKRT+IE++ K  LES F+K PKP+A  I SL++ + ++KEVVRVWFCNRRQ
Sbjct:  178 MGHQDPRALDHRHPSESGEEEAPSSD----DLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLAKWLEEAD-STTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFHKQPKPSAQEIASLADSLQLEKEVVRVWFCNRRQ 342

[Close]

BLAST of POU domain protein vs. TrEMBL
Match: A0A3Q3X5P6 (POU domain protein OS=Mola mola OX=94237 PE=3 SV=1)

HSP 1 Score: 219.935 bits (559), Expect = 3.951e-63
Identity = 115/180 (63.89%), Postives = 138/180 (76.67%), Query Frame = 1

Query:  910 SYQSSNSMSLLGSQQPEISKDLFLSDSIIENSKLSTMDCRELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            S  ++N  SL+ SQ P  S       S  E+S   T    +LEQFAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL+KWLEEAD S S +  +++K+A Q R+RKKRT+IE++ K  LES F K PKP+A+ IISL++ + ++KEVVRVWFCNRRQ
Sbjct:  121 SMATTNGQSLIYSQ-PGFSHQ-HRPQSHHEHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEAD-STSGSPTSLDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSASEIISLADSLHLEKEVVRVWFCNRRQ 297

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BLAST of POU domain protein vs. Ensembl Cavefish
Match: POU3F4 (POU class 3 homeobox 4 [Source:NCBI gene;Acc:103039910])

HSP 1 Score: 214.542 bits (545), Expect = 3.748e-64
Identity = 104/160 (65.00%), Postives = 127/160 (79.38%), Query Frame = 1

Query:  970 DLFLSDSIIENSKLSTMDCRELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            D+  +    ++S   T    ELEQFAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL+KWLEEAD S + +  +++K+A Q R+RKKRT+IE++ K +LE+ F K PKP A  I SL++ + ++KEVVRVWFCNRRQ
Sbjct:  165 DVTAAHHCHDHSDEETPTSDELEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEAD-SSTGSPSSIDKIAAQGRKRKKRTSIEVSVKGVLETHFLKCPKPAAQEISSLADSLQLEKEVVRVWFCNRRQ 323

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BLAST of POU domain protein vs. Ensembl Cavefish
Match: pou3f2a (POU class 3 homeobox 2a [Source:ZFIN;Acc:ZDB-GENE-980526-139])

HSP 1 Score: 209.149 bits (531), Expect = 4.550e-63
Identity = 101/140 (72.14%), Postives = 115/140 (82.14%), Query Frame = 1

Query: 1030 ELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            +LEQFA+ FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL KWLEEAD   S     ++KLA   R+RKKRT+IE++ K  LES F K PKP AA I SL++ + ++KEVVRVWFCNRRQ
Sbjct:   82 DLEQFARQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLGKWLEEADCGASGP-AGLDKLAAHGRKRKKRTSIEVSVKGALESHFLKCPKPAAAEITSLADSLRLEKEVVRVWFCNRRQ 220

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BLAST of POU domain protein vs. Ensembl Cavefish
Match: pou3f3a (POU class 3 homeobox 3 [Source:NCBI gene;Acc:103040687])

HSP 1 Score: 213.772 bits (543), Expect = 4.808e-63
Identity = 101/140 (72.14%), Postives = 120/140 (85.71%), Query Frame = 1

Query: 1030 ELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            +LEQFAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL+KWLEEAD S + +  +++K+A Q R+RKKRT+IE++ K  LES F K PKP+A  I SL++ + ++KEVVRVWFCNRRQ
Sbjct:  249 DLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEAD-STTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITSLADNLQLEKEVVRVWFCNRRQ 387

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BLAST of POU domain protein vs. Ensembl Cavefish
Match: ENSAMXT00000041388.1 (POU domain, class 3, transcription factor 3-B-like [Source:NCBI gene;Acc:103021364])

HSP 1 Score: 211.846 bits (538), Expect = 4.061e-62
Identity = 100/140 (71.43%), Postives = 119/140 (85.00%), Query Frame = 1

Query: 1030 ELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            +LE FAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL+KWLEEAD S + +  +++K+A Q R+RKKRT+IE++ K  LES F K PKP+A  I SL++ + ++KEVVRVWFCNRRQ
Sbjct:  249 DLEHFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEAD-SSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITSLADNLQLEKEVVRVWFCNRRQ 387

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BLAST of POU domain protein vs. Ensembl Cavefish
Match: pou3f1 (POU class 3 homeobox 1 [Source:NCBI gene;Acc:30398])

HSP 1 Score: 209.149 bits (531), Expect = 4.643e-62
Identity = 100/140 (71.43%), Postives = 117/140 (83.57%), Query Frame = 1

Query: 1030 ELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            +LEQFAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL+KWLEE D S S +  N++K+A Q R+RKKRT+IE+  K  LE+ F K PKP+A  I +L+  + ++KEVVRVWFCNRRQ
Sbjct:  186 DLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEETD-SNSGSPTNLDKIAAQGRKRKKRTSIEVGVKGALENHFLKCPKPSAHEISTLAGTLQLEKEVVRVWFCNRRQ 324

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BLAST of POU domain protein vs. Ensembl Sea Lamprey
Match: pou2f1b (POU class 2 homeobox 1b [Source:ZFIN;Acc:ZDB-GENE-030131-2422])

HSP 1 Score: 173.711 bits (439), Expect = 2.136e-49
Identity = 88/148 (59.46%), Postives = 106/148 (71.62%), Query Frame = 1

Query: 1021 DCRELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEE-----ADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            D  ELE FAK FKQRRIKLGFTQ DVGLA+G LYGN FSQTTI RFEAL LSFKNM KL+PLL KWL +     AD S  N   +   L    R+RKKRT+I+ + +  LE SF ++ KPT+  +  ++E++ M+KEVVRVWFCNRRQ
Sbjct:  211 DLEELEVFAKMFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDTEHIPADSSPGNQNASPSGLEGLGRRRKKRTSIDTHVRVALEKSFLENCKPTSEELSMIAEQLHMEKEVVRVWFCNRRQ 358

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BLAST of POU domain protein vs. Ensembl Sea Lamprey
Match: pou4f2 (POU class 4 homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-040401-1])

HSP 1 Score: 141.739 bits (356), Expect = 9.143e-38
Identity = 74/147 (50.34%), Postives = 99/147 (67.35%), Query Frame = 1

Query: 1021 DCRELEQFAKTFKQRRIKLGFTQADVGLALGTL----YGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            D RELE FA+ FKQRRIKLG TQADVG ALG L     G++ SQ+TICRFE+L LS  NM  L+P+L  WLEEA+ +  N     + L N   +++KRT+I    K  LE+ F   P+P++  I +++E++ + K VVRVWFCN+RQ
Sbjct:  207 DPRELEAFAERFKQRRIKLGVTQADVGSALGNLKIPGVGSL-SQSTICRFESLTLSHNNMIALKPILQAWLEEAEKAHRNKQTKPD-LFNGGEKKRKRTSIAAPEKRSLEAYFAVQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQ 351

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BLAST of POU domain protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002675.1 (pep scaffold:Pmarinus_7.0:GL479714:4410:5816:-1 gene:ENSPMAG00000002443.1 transcript:ENSPMAT00000002675.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 118.627 bits (296), Expect = 2.171e-31
Identity = 57/147 (38.78%), Postives = 87/147 (59.18%), Query Frame = 1

Query: 1015 TMDCRELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQ--NRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
             +D  E+ +FAK FK RR+ LG TQ  VG AL    G  +SQ+ ICRFE L L+ K+  K+RP+L +W+ EA+         +        +++RK+RT+       IL + F+    PT+A +  ++E++  D+EVVR+WFCN+RQ
Sbjct:    2 AVDLEEIREFAKVFKLRRLALGLTQTQVGQALSAAEGPAYSQSAICRFEKLDLTPKSAQKMRPILERWMGEAEARHRMGTHTLTDFIGSEPSKRRKRRTSFTQEALVILNAHFDVGMHPTSAEMTQIAEQLGYDREVVRIWFCNKRQ 148

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BLAST of POU domain protein vs. Ensembl Sea Lamprey
Match: pou6f2 (POU class 6 homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-091118-71])

HSP 1 Score: 121.324 bits (303), Expect = 5.164e-31
Identity = 53/151 (35.10%), Postives = 93/151 (61.59%), Query Frame = 1

Query: 1003 SKLSTMDCRELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQ--NRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
             ++  ++  E+ +FA+ FK RR+ LG TQ  VG AL    G  +SQ+ ICRFE L ++ K+  K++P+L +W+EEA+      + ++        +++RK+RT+      ++L + F ++  P+   + +++ER+  D+EVVRVWFCN+RQ
Sbjct:  136 GEVDGVNLEEMREFARAFKIRRLSLGLTQTQVGQALSAAEGPAYSQSAICRFEKLDITPKSAQKIKPVLERWMEEAEARKQAGLQSLSDFVGGEPSKKRKRRTSFTPQALELLNAHFERNTHPSGQEMTAIAERLCYDREVVRVWFCNKRQ 286

[Close]

BLAST of POU domain protein vs. Ensembl Sea Lamprey
Match: pou6f2 (POU class 6 homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-091118-71])

HSP 1 Score: 120.553 bits (301), Expect = 7.994e-31
Identity = 53/151 (35.10%), Postives = 93/151 (61.59%), Query Frame = 1

Query: 1003 SKLSTMDCRELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQ--NRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
             ++  ++  E+ +FA+ FK RR+ LG TQ  VG AL    G  +SQ+ ICRFE L ++ K+  K++P+L +W+EEA+      + ++        +++RK+RT+      ++L + F ++  P+   + +++ER+  D+EVVRVWFCN+RQ
Sbjct:  133 GEVDGVNLEEMREFARAFKIRRLSLGLTQTQVGQALSAAEGPAYSQSAICRFEKLDITPKSAQKIKPVLERWMEEAEARKQAGLQSLSDFVGGEPSKKRKRRTSFTPQALELLNAHFERNTHPSGQEMTAIAERLCYDREVVRVWFCNKRQ 283

[Close]

BLAST of POU domain protein vs. Ensembl Nematostella
Match: EDO33532 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRV9])

HSP 1 Score: 213.386 bits (542), Expect = 1.747e-66
Identity = 110/187 (58.82%), Postives = 132/187 (70.59%), Query Frame = 1

Query:  889 LNIPTAFSYQSSNSMSLLGSQQPEISKDLFLSDSIIENSKLSTMDCRELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            + +P +F+  +       G Q P++  D+  +D     S        +LEQFAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL KWLEEAD + +     V+KLA   R+RKKRT+IE+  K  LE+ F K PKPTA  I +L+E + +DKEVVRVWFCNRRQ
Sbjct:    1 MTLPASFAPNNQTIRENPGVQDPQLQHDILDADDDTPTSD-------DLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLQKWLEEAD-NNNGATGGVDKLATTGRKRKKRTSIEVAVKGALENHFCKSPKPTAQEISALAENLGLDKEVVRVWFCNRRQ 179

[Close]

BLAST of POU domain protein vs. Ensembl Nematostella
Match: EDO43881 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXQ0])

HSP 1 Score: 177.563 bits (449), Expect = 4.092e-53
Identity = 89/149 (59.73%), Postives = 108/149 (72.48%), Query Frame = 1

Query: 1030 ELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEK------LANQN---RQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            EL  FAK F+QRR+ LGFTQADVG+ALGTLYGNV SQTTICRFEALQLS KNM KL+PLL KWL+E D S S      ++       A  N   ++RK+RT IE N K +LE+ F K P+P+ + I SL+E + +D+EVVRVWFCNRRQ
Sbjct:    8 ELSTFAKQFRQRRVALGFTQADVGVALGTLYGNVLSQTTICRFEALQLSLKNMCKLKPLLQKWLQETDASSSGHEGEKQQNPSNFAFATHNGPYKKRKRRTIIEKNVKGVLENHFEKMPRPSTSDISSLAESLGLDREVVRVWFCNRRQ 156

[Close]

BLAST of POU domain protein vs. Ensembl Nematostella
Match: EDO30968 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SZ94])

HSP 1 Score: 166.007 bits (419), Expect = 4.613e-49
Identity = 83/140 (59.29%), Postives = 102/140 (72.86%), Query Frame = 1

Query: 1057 KQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEK------LANQN---RQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            +QRR+ LGFTQADVG+ALGTLYGNV SQTTICRFEALQLS KNM KL+PLL KWL+E D S S      ++       A  N   ++RK+RT IE N K +LE+ F K P+P+ + I SL+E + +D+EVVRVWFCNRRQ
Sbjct:    1 RQRRVALGFTQADVGVALGTLYGNVLSQTTICRFEALQLSLKNMCKLKPLLQKWLQETDASSSGHEGEKQQNPSNFAFATHNGPYKKRKRRTIIEKNVKGVLENHFEKMPRPSTSDISSLAESLGLDREVVRVWFCNRRQ 140

[Close]

BLAST of POU domain protein vs. Ensembl Nematostella
Match: EDO38767 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SC36])

HSP 1 Score: 159.073 bits (401), Expect = 3.470e-46
Identity = 79/141 (56.03%), Postives = 102/141 (72.34%), Query Frame = 1

Query: 1027 RELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            RELE+FA  FK RRIKLGFTQ +VG AL  ++G  FSQTTICRFE LQLSFKN  KL+P+L++WLEEA+ S        EK   + R+RK+RT I +  K+ LE+ F K  KP++  I+ +++ + +DKEVVRVWFCNRRQ
Sbjct:    7 RELEEFATQFKLRRIKLGFTQTNVGAALAAVHGTDFSQTTICRFENLQLSFKNACKLKPILARWLEEAERSGGAC---GEKFGAE-RRRKRRTTIGLAAKEALENHFMKQTKPSSPEIVRIADGLRLDKEVVRVWFCNRRQ 143

[Close]

BLAST of POU domain protein vs. Ensembl Nematostella
Match: EDO47033 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNB5])

HSP 1 Score: 136.346 bits (342), Expect = 8.803e-38
Identity = 75/148 (50.68%), Postives = 101/148 (68.24%), Query Frame = 1

Query: 1018 MDCRELEQFAKTFKQRRIKLGFTQADVGLALGTL----YGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            M+ RELE FA+ FKQRRIKLG TQADVG AL  L     G++ SQ+TICRFE+L LS  NM  L+P+L+ WLEEA+ +      N   L N +++R KRT+I    K  LE+ F  +P+P++  I S++E++ + K VVRVWFCN+RQ
Sbjct:    1 MNPRELEWFAERFKQRRIKLGVTQADVGSALAHLKIPGVGSL-SQSTICRFESLTLSHNNMMALKPVLTAWLEEAEKAYKTKQCNSAFLPNSDKKR-KRTSIGAAEKRSLEAYFAMNPRPSSDKIASIAEKLDLSKNVVRVWFCNQRQ 146

[Close]

BLAST of POU domain protein vs. Ensembl Medaka
Match: pou3f2b (POU domain, class 3, transcription factor 2 [Source:NCBI gene;Acc:101159940])

HSP 1 Score: 217.624 bits (553), Expect = 8.154e-66
Identity = 103/140 (73.57%), Postives = 121/140 (86.43%), Query Frame = 1

Query: 1030 ELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            +LEQFAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL+KWLEEAD S S +  +++K+A Q R+RKKRT+IE++ K  LES F K PKP A+ IISL++ + ++KEVVRVWFCNRRQ
Sbjct:  154 DLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEAD-STSGSPTSLDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPAASEIISLADNLHLEKEVVRVWFCNRRQ 292

[Close]

BLAST of POU domain protein vs. Ensembl Medaka
Match: pou3f2a (POU domain, class 3, transcription factor 2-like [Source:NCBI gene;Acc:111947099])

HSP 1 Score: 217.624 bits (553), Expect = 1.579e-65
Identity = 104/140 (74.29%), Postives = 119/140 (85.00%), Query Frame = 1

Query: 1030 ELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            ELEQFAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL+KWLEEAD S S +  +++K+A Q R+RKKRT+IE+  K  LES F K PKP AA I SL++ + ++KEVVRVWFCNRRQ
Sbjct:  175 ELEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEAD-STSGSPTSLDKIAAQGRKRKKRTSIEVGVKGALESHFLKCPKPGAAEINSLADSLQLEKEVVRVWFCNRRQ 313

[Close]

BLAST of POU domain protein vs. Ensembl Medaka
Match: pou3f3a (POU domain, class 3, transcription factor 3-B [Source:NCBI gene;Acc:101174234])

HSP 1 Score: 212.231 bits (539), Expect = 1.802e-63
Identity = 100/140 (71.43%), Postives = 119/140 (85.00%), Query Frame = 1

Query: 1030 ELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            +LE FAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL+KWLEEAD S + +  +++K+A Q R+RKKRT+IE++ K  LES F K PKP+A  I SL++ + ++KEVVRVWFCNRRQ
Sbjct:  164 DLEHFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEAD-STTGSPTSIDKIATQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEINSLADTLQLEKEVVRVWFCNRRQ 302

[Close]

BLAST of POU domain protein vs. Ensembl Medaka
Match: pou3f3b (POU domain, class 3, transcription factor 3-B [Source:NCBI gene;Acc:101162433])

HSP 1 Score: 212.231 bits (539), Expect = 1.770e-62
Identity = 100/139 (71.94%), Postives = 119/139 (85.61%), Query Frame = 1

Query: 1033 LEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            LEQFAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL+KWLEEAD S + +  +++K+A Q R+RKKRT+IE++ K  LES F K PKP+A  I +L++ + ++KEVVRVWFCNRRQ
Sbjct:  244 LEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEAD-SSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEISTLADNLQLEKEVVRVWFCNRRQ 381

[Close]

BLAST of POU domain protein vs. Ensembl Medaka
Match: pou3f3b (POU domain, class 3, transcription factor 3-B [Source:NCBI gene;Acc:101162433])

HSP 1 Score: 212.231 bits (539), Expect = 2.054e-62
Identity = 100/139 (71.94%), Postives = 119/139 (85.61%), Query Frame = 1

Query: 1033 LEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            LEQFAK FKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KL+PLL+KWLEEAD S + +  +++K+A Q R+RKKRT+IE++ K  LES F K PKP+A  I +L++ + ++KEVVRVWFCNRRQ
Sbjct:  244 LEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEAD-SSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEISTLADNLQLEKEVVRVWFCNRRQ 381

[Close]

BLAST of POU domain protein vs. Planmine SMEST
Match: SMESG000008858.1 (SMESG000008858.1)

HSP 1 Score: 941.414 bits (2432), Expect = 0.000e+0
Identity = 454/454 (100.00%), Postives = 454/454 (100.00%), Query Frame = 1

Query:   88 MSISENNKEKDIIYGLEAKHIVDFNVASHLDEEQDAISKSIGRNQKTDKHSQSLNGKTPNEPLDHNSYIKAYNDALFEQRTNFNGLNSDLSYSFLSQYGYNNDERMDFTPYSLPIDMIEQSYNSWSKSNACTFTEAHLNSPWYNHYPYPGYASYNSYMCNIPPVATSSINDQSNMSFPNHPAFSDLEEYEQLKQFQASNYSVFPQDSFLNHSISTLMPPLRNSQSTTPFNSINPSSHWLDVKNWPKSASQSDQFDQNSLKRQIDHFPLNIPTAFSYQSSNSMSLLGSQQPEISKDLFLSDSIIENSKLSTMDCRELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            MSISENNKEKDIIYGLEAKHIVDFNVASHLDEEQDAISKSIGRNQKTDKHSQSLNGKTPNEPLDHNSYIKAYNDALFEQRTNFNGLNSDLSYSFLSQYGYNNDERMDFTPYSLPIDMIEQSYNSWSKSNACTFTEAHLNSPWYNHYPYPGYASYNSYMCNIPPVATSSINDQSNMSFPNHPAFSDLEEYEQLKQFQASNYSVFPQDSFLNHSISTLMPPLRNSQSTTPFNSINPSSHWLDVKNWPKSASQSDQFDQNSLKRQIDHFPLNIPTAFSYQSSNSMSLLGSQQPEISKDLFLSDSIIENSKLSTMDCRELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ
Sbjct:    1 MSISENNKEKDIIYGLEAKHIVDFNVASHLDEEQDAISKSIGRNQKTDKHSQSLNGKTPNEPLDHNSYIKAYNDALFEQRTNFNGLNSDLSYSFLSQYGYNNDERMDFTPYSLPIDMIEQSYNSWSKSNACTFTEAHLNSPWYNHYPYPGYASYNSYMCNIPPVATSSINDQSNMSFPNHPAFSDLEEYEQLKQFQASNYSVFPQDSFLNHSISTLMPPLRNSQSTTPFNSINPSSHWLDVKNWPKSASQSDQFDQNSLKRQIDHFPLNIPTAFSYQSSNSMSLLGSQQPEISKDLFLSDSIIENSKLSTMDCRELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 454

[Close]

BLAST of POU domain protein vs. Planmine SMEST
Match: SMESG000057970.1 (SMESG000057970.1)

HSP 1 Score: 209.92 bits (533), Expect = 1.697e-60
Identity = 104/140 (74.29%), Postives = 119/140 (85.00%), Query Frame = 1

Query: 1030 ELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            +LEQFAK FKQRRIKLG+TQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM KLRPLL KWL EAD S S +  N +K++ Q+R+RKKRT+IE N K ILESSF K  KP+A  I SL+E++ ++KEVVRVWFCNRRQ
Sbjct:  272 DLEQFAKMFKQRRIKLGYTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLRPLLQKWLHEAD-SSSESPTNFDKISAQSRKRKKRTSIEANVKLILESSFMKLSKPSAQDISSLAEKLSLEKEVVRVWFCNRRQ 410

[Close]

BLAST of POU domain protein vs. Planmine SMEST
Match: SMESG000076173.1 (SMESG000076173.1)

HSP 1 Score: 203.756 bits (517), Expect = 4.091e-59
Identity = 102/164 (62.20%), Postives = 123/164 (75.00%), Query Frame = 1

Query:  970 DLFLSDSIIENSKLSTMDCR----ELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            D  L D I  N ++S ++ +    ELEQFAK FKQRRIKLGFTQADVGLALG LYG+VFSQTTICRFEALQLSFKNM KLRPLL KWL+EAD S       ++K+    R+RKKRT+IE+  K+ LES F++  KPTA  I  L++ + ++KEVVRVWFCNRRQ
Sbjct:  190 DTELQDQIDSNGEISRLNQKISTDELEQFAKIFKQRRIKLGFTQADVGLALGNLYGSVFSQTTICRFEALQLSFKNMCKLRPLLGKWLQEAD-STGCAPSGIDKVTAAGRKRKKRTSIEVGVKNALESHFSRQSKPTAQIITQLADSLGLEKEVVRVWFCNRRQ 352

[Close]

BLAST of POU domain protein vs. Planmine SMEST
Match: SMESG000030759.1 (SMESG000030759.1)

HSP 1 Score: 135.191 bits (339), Expect = 6.100e-35
Identity = 69/147 (46.94%), Postives = 99/147 (67.35%), Query Frame = 1

Query: 1021 DCRELEQFAKTFKQRRIKLGFTQADVGLALGTL----YGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            + RELE FA+ FKQRRIKL  TQADVG ALG L     G++ SQ+TICRFE+L LS  NM  L+P+L  WLE+A+      +   +  ++ + +++KRT+I  + K  LE+ F   P+P++  II ++E++ + K VVRVWFCN+RQ
Sbjct:  192 ETRELEAFAEWFKQRRIKLRVTQADVGRALGNLKLAGVGSL-SQSTICRFESLTLSHNNMIALKPVLQTWLEDAETEAKERLNGSDAFSDIDERKRKRTSITDSEKRSLEAFFTIQPRPSSEKIIQIAEKLNLKKNVVRVWFCNQRQ 337

[Close]

BLAST of POU domain protein vs. Planmine SMEST
Match: SMESG000013430.1 (SMESG000013430.1)

HSP 1 Score: 134.806 bits (338), Expect = 1.789e-34
Identity = 70/147 (47.62%), Postives = 98/147 (66.67%), Query Frame = 1

Query: 1021 DCRELEQFAKTFKQRRIKLGFTQADVGLALGTL----YGNVFSQTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNRQRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFCNRRQ 1449
            D RELE F++ FKQRRIKLG TQADVG ALG L     G++ SQ+TICRFE+L LS  NM  L+P+L  WLEEA+   +  + N +   +   +++KRT+I    K  LE+ F   P+P++  I  +++++ + K VVRVWFCN+RQ
Sbjct:  229 DPRELEIFSERFKQRRIKLGVTQADVGKALGNLKLSGVGSL-SQSTICRFESLTLSHNNMVALKPILQAWLEEAERQAAERLKNPDIYNDSLDRKRKRTSITDAEKRSLEAYFAVQPRPSSEKIAQIADKLNLKKNVVRVWFCNQRQ 374

The following BLAST results are available for this feature:

BLAST of POU domain protein vs. Ensembl Human
BLAST of POU domain protein vs. Ensembl Celegans
BLAST of POU domain protein vs. Ensembl Fly
BLAST of POU domain protein vs. Ensembl Zebrafish
BLAST of POU domain protein vs. Ensembl Xenopus
BLAST of POU domain protein vs. Ensembl Mouse
BLAST of POU domain protein vs. UniProt/SwissProt
BLAST of POU domain protein vs. TrEMBL
BLAST of POU domain protein vs. Ensembl Cavefish
BLAST of POU domain protein vs. Ensembl Sea Lamprey
BLAST of POU domain protein vs. Ensembl Yeast
BLAST of POU domain protein vs. Ensembl Nematostella
BLAST of POU domain protein vs. Ensembl Medaka
BLAST of POU domain protein vs. Planmine SMEST

BLAST of POU domain protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
POU3F4	5.225e-64	72.14	POU class 3 homeobox 4 [Source:HGNC Symbol;Acc:HGN...	[more]
POU3F2	1.798e-63	72.86	POU class 3 homeobox 2 [Source:HGNC Symbol;Acc:HGN...	[more]
POU3F1	3.916e-62	72.14	POU class 3 homeobox 1 [Source:HGNC Symbol;Acc:HGN...	[more]
POU3F3	9.900e-62	71.43	POU class 3 homeobox 3 [Source:HGNC Symbol;Acc:HGN...	[more]
POU3F3	9.900e-62	71.43	POU class 3 homeobox 3 [Source:HGNC Symbol;Acc:HGN...	[more]

BLAST of POU domain protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ceh-6	5.340e-57	56.22	Homeobox protein ceh-6 [Source:UniProtKB/Swiss-Pr...	[more]
ceh-18	6.562e-39	41.09	Homeobox protein ceh-18 [Source:UniProtKB/Swiss-P...	[more]
ceh-18	7.853e-39	41.09	Homeobox protein ceh-18 [Source:UniProtKB/Swiss-P...	[more]
unc-86	4.484e-36	46.98	Transcription factor unc-86 [Source:UniProtKB/Swi...	[more]
unc-86	1.481e-35	46.98	Transcription factor unc-86 [Source:UniProtKB/Swi...	[more]

BLAST of POU domain protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
vvl	1.818e-64	66.45	gene:FBgn0086680 transcript:FBtr0345911	[more]
vvl	1.818e-64	66.45	gene:FBgn0086680 transcript:FBtr0076944	[more]
vvl	2.407e-62	66.45	gene:FBgn0086680 transcript:FBtr0330059	[more]
vvl	3.465e-62	66.45	gene:FBgn0086680 transcript:FBtr0346998	[more]
vvl	4.814e-62	66.45	gene:FBgn0086680 transcript:FBtr0346999	[more]

BLAST of POU domain protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pou3f2a	1.271e-64	72.86	POU class 3 homeobox 2a [Source:ZFIN;Acc:ZDB-GENE-...	[more]
pou3f2b	2.146e-64	72.86	POU class 3 homeobox 2b [Source:NCBI gene;Acc:3039...	[more]
pou3f2b	2.146e-64	72.86	POU class 3 homeobox 2b [Source:NCBI gene;Acc:3039...	[more]
pou3f3a	1.461e-63	72.14	POU class 3 homeobox 3a [Source:NCBI gene;Acc:3038...	[more]
pou3f3a	2.167e-63	72.14	POU class 3 homeobox 3a [Source:NCBI gene;Acc:3038...	[more]

BLAST of POU domain protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pou3f2	2.911e-64	72.86	POU class 3 homeobox 2 [Source:NCBI gene;Acc:10048...	[more]
pou3f4	9.525e-64	72.14	POU class 3 homeobox 4 [Source:NCBI gene;Acc:10003...	[more]
tecta.1	5.186e-63	71.43	tectorin alpha, gene 1 [Source:Xenbase;Acc:XB-GENE...	[more]
slc25a38	9.324e-63	71.43	solute carrier family 25 member 38 [Source:Xenbase...	[more]
efl1	6.995e-52	62.91	elongation factor like GTPase 1 [Source:Xenbase;Ac...	[more]

BLAST of POU domain protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Pou3f4	3.332e-64	72.14	POU domain, class 3, transcription factor 4 [Sourc...	[more]
Pou3f2	1.297e-63	72.86	POU domain, class 3, transcription factor 2 [Sourc...	[more]
Pou3f1	2.144e-62	72.14	POU domain, class 3, transcription factor 1 [Sourc...	[more]
Pou3f3	6.976e-62	71.43	POU domain, class 3, transcription factor 3 [Sourc...	[more]
Pou3f3	6.976e-62	71.43	POU domain, class 3, transcription factor 3 [Sourc...	[more]

BLAST of POU domain protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P31364\|P3F4A_XENLA	1.377e-63	72.86	POU domain, class 3, transcription factor 4-A OS=X...	[more]
sp\|P79746\|PO3F2_DANRE	1.620e-63	72.86	POU domain, class 3, transcription factor 2 OS=Dan...	[more]
sp\|P16241\|CF1A_DROME	1.822e-63	66.45	POU domain protein CF1A OS=Drosophila melanogaster...	[more]
sp\|P62516\|PO3F4_RAT	2.331e-63	72.14	POU domain, class 3, transcription factor 4 OS=Rat...	[more]
sp\|P62515\|PO3F4_MOUSE	2.331e-63	72.14	POU domain, class 3, transcription factor 4 OS=Mus...	[more]

BLAST of POU domain protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
Q23958	3.741e-68	95.58	DjPOU2 protein (Fragment) OS=Dugesia japonica OX=6...	[more]
A0A1Y3BV66	9.765e-65	62.64	POU domain protein OS=Euroglyphus maynei OX=6958 G...	[more]
A0A3S3PLI0	8.548e-64	61.20	POU domain protein OS=Dinothrombium tinctorium OX=...	[more]
B7Q3J4	1.652e-63	63.53	POU domain protein OS=Ixodes scapularis OX=6945 GN...	[more]
A0A3Q3X5P6	3.951e-63	63.89	POU domain protein OS=Mola mola OX=94237 PE=3 SV=1	[more]

BLAST of POU domain protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
POU3F4	3.748e-64	65.00	POU class 3 homeobox 4 [Source:NCBI gene;Acc:10303...	[more]
pou3f2a	4.550e-63	72.14	POU class 3 homeobox 2a [Source:ZFIN;Acc:ZDB-GENE-...	[more]
pou3f3a	4.808e-63	72.14	POU class 3 homeobox 3 [Source:NCBI gene;Acc:10304...	[more]
ENSAMXT00000041388.1	4.061e-62	71.43	POU domain, class 3, transcription factor 3-B-like...	[more]
pou3f1	4.643e-62	71.43	POU class 3 homeobox 1 [Source:NCBI gene;Acc:30398...	[more]

BLAST of POU domain protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pou2f1b	2.136e-49	59.46	POU class 2 homeobox 1b [Source:ZFIN;Acc:ZDB-GENE-...	[more]
pou4f2	9.143e-38	50.34	POU class 4 homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-0...	[more]
ENSPMAT00000002675.1	2.171e-31	38.78	pep scaffold:Pmarinus_7.0:GL479714:4410:5816:-1 ge...	[more]
pou6f2	5.164e-31	35.10	POU class 6 homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-0...	[more]
pou6f2	7.994e-31	35.10	POU class 6 homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-0...	[more]

BLAST of POU domain protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of POU domain protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO33532	1.747e-66	58.82	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO43881	4.092e-53	59.73	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO30968	4.613e-49	59.29	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO38767	3.470e-46	56.03	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO47033	8.803e-38	50.68	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of POU domain protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pou3f2b	8.154e-66	73.57	POU domain, class 3, transcription factor 2 [Sourc...	[more]
pou3f2a	1.579e-65	74.29	POU domain, class 3, transcription factor 2-like [...	[more]
pou3f3a	1.802e-63	71.43	POU domain, class 3, transcription factor 3-B [Sou...	[more]
pou3f3b	1.770e-62	71.94	POU domain, class 3, transcription factor 3-B [Sou...	[more]
pou3f3b	2.054e-62	71.94	POU domain, class 3, transcription factor 3-B [Sou...	[more]

BLAST of POU domain protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000008858.1	0.000e+0	100.00	SMESG000008858.1	[more]
SMESG000057970.1	1.697e-60	74.29	SMESG000057970.1	[more]
SMESG000076173.1	4.091e-59	62.20	SMESG000076173.1	[more]
SMESG000030759.1	6.100e-35	46.94	SMESG000030759.1	[more]
SMESG000013430.1	1.789e-34	47.62	SMESG000013430.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30021108 ID=SMED30021108|Name=POU domain protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1667bp
TTCTGGATTACGAATAGCCTATTGCAATTAATAACCGAGTTTTTTTCAAG
ATTGTCCTACAATGATCATTAAATAAAAATAATCCACATGAGTATATCAG
AAAATAATAAAGAAAAAGATATTATTTACGGCTTGGAAGCAAAGCATATT
GTAGATTTCAATGTTGCATCTCATTTAGATGAAGAACAAGACGCAATTTC
AAAATCTATTGGGCGCAACCAAAAAACTGATAAACACTCTCAGTCGTTAA
ATGGGAAAACTCCCAATGAACCACTGGATCACAATTCATATATCAAAGCC
TATAACGATGCGCTGTTTGAACAGCGGACTAATTTCAATGGTTTGAATTC
AGATTTAAGCTATTCATTTTTATCTCAGTATGGCTATAATAATGATGAAA
GAATGGATTTTACACCGTATTCTTTGCCAATTGATATGATTGAACAATCT
TATAATTCCTGGTCTAAATCTAACGCATGCACATTTACAGAGGCGCATCT
AAATTCACCTTGGTACAATCATTATCCGTATCCAGGATATGCATCATATA
ATTCTTATATGTGTAATATTCCACCGGTTGCAACTTCATCTATCAATGAT
CAATCTAATATGAGTTTTCCTAATCATCCAGCATTCTCAGATCTGGAAGA
GTATGAACAATTAAAACAATTCCAAGCAAGTAATTATTCTGTATTTCCAC
AAGATTCTTTTTTAAATCATTCAATATCAACTCTAATGCCTCCGTTAAGG
AATTCTCAAAGCACCACCCCTTTCAACTCAATCAATCCATCATCTCATTG
GTTGGATGTTAAAAATTGGCCGAAATCTGCCTCTCAATCAGATCAATTCG
ATCAAAATTCATTGAAACGTCAAATTGATCATTTTCCTTTGAATATCCCA
ACGGCGTTTTCTTATCAATCATCCAACTCAATGTCCCTACTCGGCTCTCA
ACAGCCAGAAATCAGTAAAGATCTCTTTTTGTCCGATTCCATAATTGAAA
ATTCAAAACTAAGCACGATGGACTGTCGAGAATTGGAACAATTTGCCAAG
ACTTTCAAACAAAGACGAATCAAGCTAGGATTTACTCAGGCTGATGTCGG
TCTGGCGTTGGGTACGTTATACGGGAACGTATTCAGTCAAACCACAATTT
GCCGATTTGAAGCATTACAGTTAAGCTTTAAGAACATGAACAAGTTGCGA
CCGTTATTAAGCAAATGGTTAGAAGAGGCTGATTTGTCCTTGTCAAACAC
AGTCGTGAATGTAGAGAAATTAGCGAACCAAAATCGACAAAGAAAGAAAA
GAACAAATATAGAAATGAATACCAAAGATATATTGGAATCAAGTTTCAAT
AAAGATCCAAAACCAACTGCTGCTCATATTATATCATTGTCAGAGAGAAT
TTTAATGGATAAAGAAGTAGTTCGGGTTTGGTTTTGTAATAGAAGACAGA
AAGAAAAAAAATCCAGTTTAACCAAATCTATTTCCAGTAGTTAATACAAT
CTTTCCAAAAAGAAATTCTTTTACAGATTCGACGTTTTATTATGGAAATG
GTGTGAATAAATAATTTCTTCCCATAAATTTTGCCGGTTTTCTAGCTTGT
ACAGATAAAGAAAAATACCCGTTTTTACATTTTCCTAAACTTAAAATATT
CAACATTAATTTTGAAC

protein sequence of SMED30021108-orf-1

>SMED30021108-orf-1 ID=SMED30021108-orf-1|Name=SMED30021108-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=469bp
MSISENNKEKDIIYGLEAKHIVDFNVASHLDEEQDAISKSIGRNQKTDKH
SQSLNGKTPNEPLDHNSYIKAYNDALFEQRTNFNGLNSDLSYSFLSQYGY
NNDERMDFTPYSLPIDMIEQSYNSWSKSNACTFTEAHLNSPWYNHYPYPG
YASYNSYMCNIPPVATSSINDQSNMSFPNHPAFSDLEEYEQLKQFQASNY
SVFPQDSFLNHSISTLMPPLRNSQSTTPFNSINPSSHWLDVKNWPKSASQ
SDQFDQNSLKRQIDHFPLNIPTAFSYQSSNSMSLLGSQQPEISKDLFLSD
SIIENSKLSTMDCRELEQFAKTFKQRRIKLGFTQADVGLALGTLYGNVFS
QTTICRFEALQLSFKNMNKLRPLLSKWLEEADLSLSNTVVNVEKLANQNR
QRKKRTNIEMNTKDILESSFNKDPKPTAAHIISLSERILMDKEVVRVWFC
NRRQKEKKSSLTKSISSS*

Aliases

The feature 'POU domain protein' has the following synonyms


Synonym
Dj-POU2

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0002089	reproductive organ

Vocabulary: **INTERPRO**
Term	Definition
IPR013847	POU
IPR001356	Homeobox_dom
IPR000327	POU_dom
IPR010982	Lambda_DNA-bd_dom_sf
IPR009057	Homeobox-like_sf
IPR017970	Homeobox_CS

Vocabulary: **molecular function**
Term	Definition
GO:0003677	DNA binding
GO:0003700	transcription factor activity, sequence-specific DNA binding
GO:0043565	sequence-specific DNA binding

Vocabulary: **biological process**
Term	Definition
GO:0006355	regulation of transcription, DNA-templated

Vocabulary: **cellular component**
Term	Definition
GO:0005634	nucleus

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR013847	POU domain	PRINTS	PR00028	POUDOMAIN	coord: 400..420 score: 52.28 coord: 327..344 score: 80.38 coord: 350..363 score: 89.58 coord: 435..450 score: 58.01 coord: 366..381 score: 69.01
IPR001356	Homeobox domain	SMART	SM00389	HOX_1	coord: 401..463 e-value: 5.5E-16 score: 69.1
IPR001356	Homeobox domain	PFAM	PF00046	Homeodomain	coord: 402..458 e-value: 2.2E-16 score: 59.5
IPR001356	Homeobox domain	PROSITE	PS50071	HOMEOBOX_2	coord: 399..459 score: 15.677
IPR001356	Homeobox domain	CDD	cd00086	homeodomain	coord: 402..456 e-value: 2.48985E-12 score: 59.5645
IPR000327	POU-specific domain	SMART	SM00352	pou	coord: 308..382 e-value: 2.3E-50 score: 183.3
IPR000327	POU-specific domain	PFAM	PF00157	Pou	coord: 313..382 e-value: 7.4E-36 score: 122.0
IPR000327	POU-specific domain	PROSITE	PS00035	POU_1	coord: 326..338
IPR000327	POU-specific domain	PROSITE	PS00465	POU_2	coord: 350..363
IPR000327	POU-specific domain	PROSITE	PS51179	POU_3	coord: 308..382 score: 54.549
None	No IPR available	GENE3D	G3DSA:1.10.10.60		coord: 385..451 e-value: 1.3E-18 score: 68.6
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 47..62
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 40..65
None	No IPR available	PANTHER	PTHR11636	POU DOMAIN	coord: 155..458
None	No IPR available	PANTHER	PTHR11636:SF89	POU DOMAIN PROTEIN 2, ISOFORM B-RELATED	coord: 155..458
IPR010982	Lambda repressor-like, DNA-binding domain superfamily	GENE3D	G3DSA:1.10.260.40		coord: 313..382 e-value: 1.7E-38 score: 132.4
IPR010982	Lambda repressor-like, DNA-binding domain superfamily	SUPERFAMILY	SSF47413	lambda repressor-like DNA-binding domains	coord: 311..382
IPR017970	Homeobox, conserved site	PROSITE	PS00027	HOMEOBOX_1	coord: 434..457
IPR009057	Homeobox-like domain superfamily	SUPERFAMILY	SSF46689	Homeodomain-like	coord: 390..459

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POU domain protein

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 7

Owlery

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