Ig-like domain-containing protein
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30021103 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 6
Homology
BLAST of Ig-like domain-containing protein vs. Ensembl Zebrafish
Match: hspg2 (heparan sulfate proteoglycan 2 [Source:ZFIN;Acc:ZDB-GENE-080807-4]) HSP 1 Score: 52.7582 bits (125), Expect = 3.545e-6 Identity = 37/133 (27.82%), Postives = 61/133 (45.86%), Query Frame = 2 Query: 1364 RINVVCNPATHFQCKRFAGKMCIPISQKCDSITQCEDSSDEEECNYCSDKSLSISSGQNVFKERGDTLTMTCSSTMEACYPLIWLRFNKPLEMHRNLVVF-----KQSVFVFNISSIDTGIYRCSASSNKAFI 1747 R C P F C + + CIP S +CD C D SDE C + ++++S +++ RGDT+T TCS+ + P+I R N N + + ++ + ++ D G Y C A + K + Sbjct: 342 RPGAACAPE-QFVC--LSDRKCIPASYQCDEEPDCADRSDEFGC---APPTVTVSPEESITASRGDTVTFTCSA-IGVPVPIITWRLNWGHIPANNRITMISENGQGTLTIRDVKEGDQGAYTCEAINAKGLV 467
BLAST of Ig-like domain-containing protein vs. Ensembl Zebrafish
Match: hspg2 (heparan sulfate proteoglycan 2 [Source:ZFIN;Acc:ZDB-GENE-080807-4]) HSP 1 Score: 52.7582 bits (125), Expect = 3.787e-6 Identity = 37/133 (27.82%), Postives = 61/133 (45.86%), Query Frame = 2 Query: 1364 RINVVCNPATHFQCKRFAGKMCIPISQKCDSITQCEDSSDEEECNYCSDKSLSISSGQNVFKERGDTLTMTCSSTMEACYPLIWLRFNKPLEMHRNLVVF-----KQSVFVFNISSIDTGIYRCSASSNKAFI 1747 R C P F C + + CIP S +CD C D SDE C + ++++S +++ RGDT+T TCS+ + P+I R N N + + ++ + ++ D G Y C A + K + Sbjct: 277 RPGAACAPE-QFVC--LSDRKCIPASYQCDEEPDCADRSDEFGC---APPTVTVSPEESITASRGDTVTFTCSA-IGVPVPIITWRLNWGHIPANNRITMISENGQGTLTIRDVKEGDQGAYTCEAINAKGLV 402
BLAST of Ig-like domain-containing protein vs. Ensembl Zebrafish
Match: hspg2 (heparan sulfate proteoglycan 2 [Source:ZFIN;Acc:ZDB-GENE-080807-4]) HSP 1 Score: 52.7582 bits (125), Expect = 4.192e-6 Identity = 37/133 (27.82%), Postives = 61/133 (45.86%), Query Frame = 2 Query: 1364 RINVVCNPATHFQCKRFAGKMCIPISQKCDSITQCEDSSDEEECNYCSDKSLSISSGQNVFKERGDTLTMTCSSTMEACYPLIWLRFNKPLEMHRNLVVF-----KQSVFVFNISSIDTGIYRCSASSNKAFI 1747 R C P F C + + CIP S +CD C D SDE C + ++++S +++ RGDT+T TCS+ + P+I R N N + + ++ + ++ D G Y C A + K + Sbjct: 277 RPGAACAPE-QFVC--LSDRKCIPASYQCDEEPDCADRSDEFGC---APPTVTVSPEESITASRGDTVTFTCSA-IGVPVPIITWRLNWGHIPANNRITMISENGQGTLTIRDVKEGDQGAYTCEAINAKGLV 402
BLAST of Ig-like domain-containing protein vs. Ensembl Xenopus
Match: LRP6 (LDL receptor related protein 6 [Source:NCBI gene;Acc:100489328]) HSP 1 Score: 53.1434 bits (126), Expect = 4.216e-6 Identity = 25/54 (46.30%), Postives = 32/54 (59.26%), Query Frame = 2 Query: 1379 CNPATHFQCKRFAGKM-CIPISQKCDSITQCEDSSDEEECNYCSDKSLSISSGQ 1537 C+P F C F G++ CIP +CD T+CED SDE+ C CSD +SGQ Sbjct: 1212 CSP-LQFTC--FTGEVDCIPAEWRCDGFTECEDHSDEQNCPMCSDTQYQCASGQ 1262
BLAST of Ig-like domain-containing protein vs. Ensembl Mouse
Match: Hspg2 (perlecan (heparan sulfate proteoglycan 2) [Source:MGI Symbol;Acc:MGI:96257]) HSP 1 Score: 53.1434 bits (126), Expect = 3.062e-6 Identity = 38/129 (29.46%), Postives = 59/129 (45.74%), Query Frame = 2 Query: 1376 VCNPATHFQCKRFAGKMCIPISQKCDSITQCEDSSDEEECNYCSDKSLSISSGQNVFKERGDTLTMTCSSTMEACYPLIWLRFN-KPLEMHRNLVVFKQ----SVFVFNISSIDTGIYRCSASSNKAFI 1747 VC P THFQC + CIP S CD + C D SDE C + Q++ RG T+T TC +T P+I R N + H + + + ++ + ++ D G Y C A +++ + Sbjct: 367 VCGP-THFQC--VSTNRCIPASFHCDEESDCPDRSDEFG---CMPPQVVTPPQQSIQASRGQTVTFTCVAT-GVPTPIINWRLNWGHIPAHPRVTMTSEGGRGTLIIRDVKEADQGAYTCEAMNSRGMV 488
BLAST of Ig-like domain-containing protein vs. Ensembl Mouse
Match: Hspg2 (perlecan (heparan sulfate proteoglycan 2) [Source:MGI Symbol;Acc:MGI:96257]) HSP 1 Score: 53.1434 bits (126), Expect = 3.063e-6 Identity = 38/129 (29.46%), Postives = 59/129 (45.74%), Query Frame = 2 Query: 1376 VCNPATHFQCKRFAGKMCIPISQKCDSITQCEDSSDEEECNYCSDKSLSISSGQNVFKERGDTLTMTCSSTMEACYPLIWLRFN-KPLEMHRNLVVFKQ----SVFVFNISSIDTGIYRCSASSNKAFI 1747 VC P THFQC + CIP S CD + C D SDE C + Q++ RG T+T TC +T P+I R N + H + + + ++ + ++ D G Y C A +++ + Sbjct: 367 VCGP-THFQC--VSTNRCIPASFHCDEESDCPDRSDEFG---CMPPQVVTPPQQSIQASRGQTVTFTCVAT-GVPTPIINWRLNWGHIPAHPRVTMTSEGGRGTLIIRDVKEADQGAYTCEAMNSRGMV 488
BLAST of Ig-like domain-containing protein vs. UniProt/SwissProt
Match: sp|A8X765|EGG1_CAEBR (LDL receptor repeat-containing protein egg-1 OS=Caenorhabditis briggsae OX=6238 GN=egg-1 PE=3 SV=2) HSP 1 Score: 54.299 bits (129), Expect = 6.386e-6 Identity = 62/274 (22.63%), Postives = 101/274 (36.86%), Query Frame = 2 Query: 2084 TCSYREKMCADKMKCIPSSMWCDGQKQCHDGSDEEVCNKCRNGFVIVQPSTLVILSRESTQVTCYYHKDCYPVEWRLAKDQQSVNSINGVSVMGNKLMLNNVGLEASKVYECFSGDKSSQINITVIEEVNITFIGNPGFVFVDHGGDIEVNCHSNYGEPRWSKTNFKSIEEITGAKQTYIQPNI---------AQLTIKSATYDARGYYNCSVRSPDSNRELARKLMFIHVHDLTCPEDNIKCDKNTKCIPKHKLCDNVMDCRDNSDEKNCTKC 2878 TCS + C C+P S CDG K C DGSDE CNKC+ G + + ++SR + + C V + + S L + ++ S+V + G K ++E N PG ++ + G+ +EE G + P + AQ + G ++C + + N ++ + TC + KC+ + CD V DC D SDE+NC++C Sbjct: 298 TCSKDQFKCNGSNACLPLSAKCDGVKDCSDGSDENNCNKCQKG------AHVSLVSRNIKHL--FASHVCDGVAQCADRSDEQQCDCKTCSGSDKALCDDGTCIKRSQVCD---GKKDCSDG---MDEENC-----PGTCSIEAFATKVKRVTCSDGKDYTESEACSGVEESCGGSCSKCHPKLTFTCPAAGNAQKKCIKRSKVCDGIFDCDDGADEKNCTPVKECGIDNASQFTC---------DRKCVDASRRCDGVWDCEDKSDEQNCSQC 543
BLAST of Ig-like domain-containing protein vs. TrEMBL
Match: A0A4D6FZI7 (Ig-like domain-containing protein (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 596.66 bits (1537), Expect = 0.000e+0 Identity = 289/293 (98.63%), Postives = 292/293 (99.66%), Query Frame = 2 Query: 1739 AFIDVSVNVIEPPTLKINYPSSVINITAGHDIDIICSITENKASEKQTLRPIWKFDQSKLILNNIKLNYFPNRTSILSIVKATKDVESEYTCEVLWGLGYSKKSSITVRVNVIPLTCSYREKMCADKMKCIPSSMWCDGQKQCHDGSDEEVCNKCRNGFVIVQPSTLVILSRESTQVTCYYHKDCYPVEWRLAKDQQSVNSINGVSVMGNKLMLNNVGLEASKVYECFSGDKSSQINITVIEEVNITFIGNPGFVFVDHGGDIEVNCHSNYGEPRWSKTNFKSIEEITGAKQT 2617 AFIDVSVNVIEP TLKINYPSSVINITAGHDIDIICSITENKA+EKQTLRPIWKFDQSK+ILNNIKLNYFPNRTSILS+VKATKDVESEYTCEVLWGLGYSKKSSITVRVNVIPLTCSYREKMCADKMKCIPSSMWCDGQKQCHDGSDEEVCNKCRNGFVIVQPSTLVILSRESTQVTCYYHKDCYPVEWRLAKDQQSVNSINGVSVMGNKLMLNNVGLEASKVYECFSGDKSSQINITVIEEVNITFIGNPGFVFVDHGGDIEVNCHSNYGEPRWSKTNFKSIEEITGAKQT Sbjct: 1 AFIDVSVNVIEPXTLKINYPSSVINITAGHDIDIICSITENKAAEKQTLRPIWKFDQSKMILNNIKLNYFPNRTSILSMVKATKDVESEYTCEVLWGLGYSKKSSITVRVNVIPLTCSYREKMCADKMKCIPSSMWCDGQKQCHDGSDEEVCNKCRNGFVIVQPSTLVILSRESTQVTCYYHKDCYPVEWRLAKDQQSVNSINGVSVMGNKLMLNNVGLEASKVYECFSGDKSSQINITVIEEVNITFIGNPGFVFVDHGGDIEVNCHSNYGEPRWSKTNFKSIEEITGAKQT 293 HSP 2 Score: 74.7146 bits (182), Expect = 1.499e-10 Identity = 66/278 (23.74%), Postives = 118/278 (42.45%), Query Frame = 2 Query: 2444 INITVIEEVNITFIGNPGFVFVDHGGDIEVNC--------HSNYGEPRWSKTNFKSIEEITGAKQTYIQPNIAQLTIKSATYDARGYYNCSVRSPDSNRELARKLMFIHVHDLTCPEDNIKCDKNTKCIPKHKLCDNVMDCRDNSDEKNCTKC-NFELEIKPKFILLSTAGWGNLQCIVPHKDCLPIQW-ITRNGDNLSPKNYIKYNHSLFMFNLEPQENQEII-CTNGQKSTSAFLTV-KYLDITIVPYQPDGSTLYINKGDTQIIECRSTLGTPQW 3241 +++ VIE + + + G DI++ C P W K I + K Y + L++ AT D Y C V + + + ++V LTC C KCIP CD C D SDE+ C KC N + ++P +++ + + C HKDC P++W + ++ +++ N + + M N E ++ C +G KS+ +TV + ++IT + + ++++ G + C S G P+W Sbjct: 5 VSVNVIEPXTLKINYPSSVINITAGHDIDIICSITENKAAEKQTLRPIWKFDQSKMI--LNNIKLNYFPNRTSILSMVKATKDVESEYTCEVLWGLGYSKKSSITVRVNVIPLTCSYREKMCADKMKCIPSSMWCDGQKQCHDGSDEEVCNKCRNGFVIVQPSTLVILSRESTQVTCYY-HKDCYPVEWRLAKDQQSVNSINGVSVMGNKLMLNNVGLEASKVYECFSGDKSSQINITVIEEVNITFI---GNPGFVFVDHGGDIEVNCHSNYGEPRW 276 HSP 3 Score: 62.003 bits (149), Expect = 2.834e-6 Identity = 55/198 (27.78%), Postives = 89/198 (44.95%), Query Frame = 2 Query: 1277 IIRSLSETTDVK----CQVRWGFEERGNIMTSVRINVVCNPAT-HFQCKRFAGKM-CIPISQKCDSITQCEDSSDEEECNYCSDKSLSISSGQNVFKERGDTLTMTCSSTMEACYPLIW--LRFNKPLEMHRNLVVFKQSVFVFNISSIDTGIYRCSASSNKAFIDVSVNVIEPPTLKINYPSSVINITAGHDIDIIC 1846 I+ + T DV+ C+V WG +VR+NV+ P T ++ K A KM CIP S CD QC D SDEE CN C + + + V R T +TC + CYP+ W + + + + V + + N+ + +Y C + + I+++ VIE + + + G DI++ C Sbjct: 76 ILSMVKATKDVESEYTCEVLWGLGYSKKSSITVRVNVI--PLTCSYREKMCADKMKCIPSSMWCDGQKQCHDGSDEEVCNKCRNGFVIVQPSTLVILSREST-QVTCYYHKD-CYPVEWRLAKDQQSVNSINGVSVMGNKLMLNNVGLEASKVYECFSGDKSSQINIT--VIEEVNITFIGNPGFVFVDHGGDIEVNC 267
BLAST of Ig-like domain-containing protein vs. TrEMBL
Match: A0A1B6CLV9 (Uncharacterized protein (Fragment) OS=Clastoptera arizonana OX=38151 GN=g.42728 PE=4 SV=1) HSP 1 Score: 75.0998 bits (183), Expect = 1.261e-9 Identity = 103/420 (24.52%), Postives = 161/420 (38.33%), Query Frame = 2 Query: 1556 GDTLTMTCSSTMEACYPLIWLRFNKPLEMHRNLVVFKQSVFVF-NISSIDTGIYRCSASSNKAFI-----DVSVN----VIEPPTLKINYPSSVINITAGHDIDIICSITENKASEKQTLRPIWKFDQ-SKLILNNIKLNYFPNRTSILSIVKATKDVESEYTCEVLWGLGYSKKSSITVRVNVIPLTCSYREKMCADKMKCIPSSMWCDGQKQCHDGSDEEVCNKCRNGFVI--------VQPSTLVILSRESTQVTCYYHKDC-YPVEWRLAKDQQSVNSINGVSVMGNKLMLNNVGLEASKVYECFSGDKSSQI---NITVIEEVNITFIGNPGFVFVDHGGDIEVNCHSNYGEP---RWSKTNFKSIEEITGAKQTYIQPNIAQLTIKSATYDARGYYNCSVRSPDSNRELARKLM 2737 GD + C++T E + WL + L N VV + +F NI D G Y C A + I DV VN V ++Y S + + D D I + SE P F Q S LIL+N+KL + Y C+ G +S + + V P C +E C + +CI + CDGQ C D SDE +C R G + ++PS ++ +S V C+ + V W + + N G+ L ++N E S V+ C + ++ + + + E NI V++G I + C ++ P W+K ++ N L I S TY+ G Y CS + + E+ R L+ Sbjct: 2658 GDNAQILCTATGEEPIEITWLAIGRDLP---NSVVTRGGQILFRNIKLSDAGRYMCRARDARGQIAESNSDVIVNEHNYVKAVDRHPVSYEGSSVRLQC--DTDTHTQIIWTRDSEP---LPRNSFIQGSVLILDNLKL-----------------EDGGRYICQTDTSTG---TASDYIELRVEPSGCGMKEFRCGNG-ECIELDLVCDGQPHCQDRSDETICGA-RQGRGLDSEPMELGIEPSKDIVNFGDSVDVRCFDKRSSNTKVYWSKVQSSMAFNE----RTSGDMLRIDNANTENSGVFRCTAQSQNGHVVEKDYVLNVEGNIPINNEVQQFSVNYGDIIPLECQTDLEPPVTYTWTKQG--------SVLPSHSTANGILLNISSVTYEDAGLYICSANNSNVRMEIPRLLL 3035
BLAST of Ig-like domain-containing protein vs. TrEMBL
Match: A0A1B6EDX6 (Uncharacterized protein OS=Clastoptera arizonana OX=38151 GN=g.42720 PE=4 SV=1) HSP 1 Score: 74.7146 bits (182), Expect = 1.613e-9 Identity = 103/420 (24.52%), Postives = 161/420 (38.33%), Query Frame = 2 Query: 1556 GDTLTMTCSSTMEACYPLIWLRFNKPLEMHRNLVVFKQSVFVF-NISSIDTGIYRCSASSNKAFI-----DVSVN----VIEPPTLKINYPSSVINITAGHDIDIICSITENKASEKQTLRPIWKFDQ-SKLILNNIKLNYFPNRTSILSIVKATKDVESEYTCEVLWGLGYSKKSSITVRVNVIPLTCSYREKMCADKMKCIPSSMWCDGQKQCHDGSDEEVCNKCRNGFVI--------VQPSTLVILSRESTQVTCYYHKDC-YPVEWRLAKDQQSVNSINGVSVMGNKLMLNNVGLEASKVYECFSGDKSSQI---NITVIEEVNITFIGNPGFVFVDHGGDIEVNCHSNYGEP---RWSKTNFKSIEEITGAKQTYIQPNIAQLTIKSATYDARGYYNCSVRSPDSNRELARKLM 2737 GD + C++T E + WL + L N VV + +F NI D G Y C A + I DV VN V ++Y S + + D D I + SE P F Q S LIL+N+KL + Y C+ G +S + + V P C +E C + +CI + CDGQ C D SDE +C R G + ++PS ++ +S V C+ + V W + + N G+ L ++N E S V+ C + ++ + + + E NI V++G I + C ++ P W+K ++ N L I S TY+ G Y CS + + E+ R L+ Sbjct: 2714 GDNAQILCTATGEEPIEITWLAIGRDLP---NSVVTRGGQILFRNIKLSDAGRYMCRARDARGQIAESNSDVIVNEHNYVKAVDRHPVSYEGSSVRLQC--DTDTHTQIIWTRDSEP---LPRNSFIQGSVLILDNLKL-----------------EDGGRYICQTDTSTG---TASDYIELRVEPSGCGMKEFRCGNG-ECIELDLVCDGQPHCQDRSDETICGA-RQGRGLDSEPMELGIEPSKDIVNFGDSVDVRCFDKRSSNTKVYWSKVQSSMAFNE----RTSGDMLRIDNANTENSGVFRCTAQSQNGHVVEKDYVLNVEGNIPINNEVQQFSVNYGDIIPLECQTDLEPPVTYTWTKQG--------SVLPSHSTANGILLNISSVTYEDAGLYICSANNSNVRMEIPRLLL 3091
BLAST of Ig-like domain-containing protein vs. TrEMBL
Match: A0A1B6DS91 (Uncharacterized protein (Fragment) OS=Clastoptera arizonana OX=38151 GN=g.42739 PE=4 SV=1) HSP 1 Score: 74.7146 bits (182), Expect = 1.687e-9 Identity = 103/420 (24.52%), Postives = 161/420 (38.33%), Query Frame = 2 Query: 1556 GDTLTMTCSSTMEACYPLIWLRFNKPLEMHRNLVVFKQSVFVF-NISSIDTGIYRCSASSNKAFI-----DVSVN----VIEPPTLKINYPSSVINITAGHDIDIICSITENKASEKQTLRPIWKFDQ-SKLILNNIKLNYFPNRTSILSIVKATKDVESEYTCEVLWGLGYSKKSSITVRVNVIPLTCSYREKMCADKMKCIPSSMWCDGQKQCHDGSDEEVCNKCRNGFVI--------VQPSTLVILSRESTQVTCYYHKDC-YPVEWRLAKDQQSVNSINGVSVMGNKLMLNNVGLEASKVYECFSGDKSSQI---NITVIEEVNITFIGNPGFVFVDHGGDIEVNCHSNYGEP---RWSKTNFKSIEEITGAKQTYIQPNIAQLTIKSATYDARGYYNCSVRSPDSNRELARKLM 2737 GD + C++T E + WL + L N VV + +F NI D G Y C A + I DV VN V ++Y S + + D D I + SE P F Q S LIL+N+KL + Y C+ G +S + + V P C +E C + +CI + CDGQ C D SDE +C R G + ++PS ++ +S V C+ + V W + + N G+ L ++N E S V+ C + ++ + + + E NI V++G I + C ++ P W+K ++ N L I S TY+ G Y CS + + E+ R L+ Sbjct: 2839 GDNAQILCTATGEEPIEITWLAIGRDLP---NSVVTRGGQILFRNIKLSDAGRYMCRARDARGQIAESNSDVIVNEHNYVKAVDRHPVSYEGSSVRLQC--DTDTHTQIIWTRDSEP---LPRNSFIQGSVLILDNLKL-----------------EDGGRYICQTDTSTG---TASDYIELRVEPSGCGMKEFRCGNG-ECIELDLVCDGQPHCQDRSDETICGA-RQGRGLDSEPMELGIEPSKDIVNFGDSVDVRCFDKRSSNTKVYWSKVQSSMAFNE----RTSGDMLRIDNANTENSGVFRCTAQSQNGHVVEKDYVLNVEGNIPINNEVQQFSVNYGDIIPLECQTDLEPPVTYTWTKQG--------SVLPSHSTANGILLNISSVTYEDAGLYICSANNSNVRMEIPRLLL 3216
BLAST of Ig-like domain-containing protein vs. TrEMBL
Match: H9JRT0 (Uncharacterized protein OS=Bombyx mori OX=7091 PE=4 SV=1) HSP 1 Score: 66.6254 bits (161), Expect = 5.688e-7 Identity = 54/224 (24.11%), Postives = 94/224 (41.96%), Query Frame = 2 Query: 2216 VIVQPSTLVILSRESTQVTCYYHKD-CYPVEWRLAKDQQSVNSINGVSVMGNKLMLNNVGLEASKVYECFS----GDKSSQINITVIEEVN-ITFIGNPGFVFVDHGGDIEVNCHSNYGEPRWSKTNFKSIEEITGAKQTYIQPNIAQLTIKSATYDARGYYNCSVRSPDSNRELARKLMFIHVHDLTCPEDNIKCDKNTKCIPKHKLCDNVMDCRDNSDEKNC 2869 + ++P+ + +S V C D V WR ++ V + G L+ NN+ +E + +Y C + G+ ++ N+ V E + T + + G + + C N +P K + ++Q L IK A G Y C VR D + + +H+ + C E + +C N+ CI K +C+ DC D+SDE+NC Sbjct: 2757 ITLRPANQTVRPGQSLTVECLVEGDEILDVTWRYDREPSRR-----VEIRGPVLVFNNIEVEDAGIYYCIARSRYGNDTATANVIVTENTDRPTVESHNNEQYAHSGAAVHLGC--NVSQPNLRIYWTKDGRPVPRSRQK----TDGSLFIKVAQKSDSGRYECFVR--DQYGRRSSNYVNLHIEGIKCSELDFRCSDNSGCIDKSLVCNGFRDCYDDSDEENC 2967
BLAST of Ig-like domain-containing protein vs. Planmine SMEST
Match: SMESG000042512.1 (SMESG000042512.1) HSP 1 Score: 2293.85 bits (5943), Expect = 0.000e+0 Identity = 1107/1111 (99.64%), Postives = 1110/1111 (99.91%), Query Frame = 2 Query: 53 MTVNNVIIYFFLVYFNLKFIYPQITNGESRSKNVIDLHDGSGNGHENVNHHLNAKLMTLDDEDSMKTTNSKILQSSGDGQPEPPDMYPTLHPYAKSRSTATIIVDIAIESDFKSYMLPGSPFSSDLNAFYKKVIRNLQEELSQINVDLGFKIISLRPGPLISKRHSIKAPEAHSPSVFARINVTQYNSSIVNPMIIFHISHCGRLGILGNLTISDQVIFPLYVCPNDHVYCLPNCRKGTYCDGIVDCPSSNLDEAPSCPKCLYKTLQLTSNTEYLNEGENLVLSCNLKESCNELQNKIEWSFPGQLEKYQIRFRGERWINSLPKNKISSGIYKCHLDEESAIKNITVFKRPDVFITNTVSNAVELIMTESYGSDINLWCNCSEGHAQWNNVESTNGYVNQMDREHSKLIIRSLSETTDVKCQVRWGFEERGNIMTSVRINVVCNPATHFQCKRFAGKMCIPISQKCDSITQCEDSSDEEECNYCSDKSLSISSGQNVFKERGDTLTMTCSSTMEACYPLIWLRFNKPLEMHRNLVVFKQSVFVFNISSIDTGIYRCSASSNKAFIDVSVNVIEPPTLKINYPSSVINITAGHDIDIICSITENKASEKQTLRPIWKFDQSKLILNNIKLNYFPNRTSILSIVKATKDVESEYTCEVLWGLGYSKKSSITVRVNVIPLTCSYREKMCADKMKCIPSSMWCDGQKQCHDGSDEEVCNKCRNGFVIVQPSTLVILSRESTQVTCYYHKDCYPVEWRLAKDQQSVNSINGVSVMGNKLMLNNVGLEASKVYECFSGDKSSQINITVIEEVNITFIGNPGFVFVDHGGDIEVNCHSNYGEPRWSKTNFKSIEEITGAKQTYIQPNIAQLTIKSATYDARGYYNCSVRSPDSNRELARKLMFIHVHDLTCPEDNIKCDKNTKCIPKHKLCDNVMDCRDNSDEKNCTKCNFELEIKPKFILLSTAGWGNLQCIVPHKDCLPIQWITRNGDNLSPKNYIKYNHSLFMFNLEPQENQEIICTNGQKSTSAFLTVKYLDITIVPYQPDGSTLYINKGDTQIIECRSTLGTPQWIFPRLNLLSNFGVRYLTDEPNVAKILLTNVQENASGLYVCSVAFTRET 3385 MTVNNVIIYFFLVYFNLKFIYPQITNGESRSKNVIDLHDGSGNGHENVNHHLNAKL+TLDDEDSMKTTNSKILQSSGDGQPEPPDMYPTLHPYAKSRSTATIIVDIAIESDFKSYMLPGSPFSSDLNAFYKKVIRNLQEELSQINVDLGFKIISLRPGPLISKRHSIKAPEAHSPSVFARINVTQYNSSIVNPMIIFHISHCGRLGILGNLTISDQVIFPLYVCPNDHVYCLPNCRKGTYCDGIVDCPSSNLDEAPSCPKCLYKTLQLTSNTEYLNEGENLVLSCNLKESCNELQNKIEWSFPGQLEKYQIRFRGERWINSLPKNKISSGIYKCHLDE+SAIKNITVFKRPDVFITNTVSNAVELIMTESYGSDINLWCNCSEGHAQWNNVESTNGYVNQMDREHSKLIIRSLSETTDVKCQVRWGFEERGNIMTSVRINVVCNPATHFQCKRFAGKMCIPISQKCDSITQCEDSSDEEECNYCSDKSLSISSGQNVFKERGDTLTMTCSSTMEACYPLIWLRFNKPLEMHRNLVVFKQSVFVFNISSIDTGIYRCSASSNKAFIDVSVNVIEPPTLKINYPSSVINITAGHDIDIICSITE +ASEKQTLRPIWKFDQSKLILNNIKLNYFPNRTSILSIVKATKDVESEYTCEVLWGLGYSKKSSITVRVNVIPLTCSYREKMCADKMKCIPSSMWCDGQKQCHDGSDEEVCNKCRNGFVIVQPSTLVILSRESTQVTCYYHKDCYPVEWRLAKDQQSVNSINGVSVMGNKLMLNNVGLEASKVYECFSGDKSSQINITVIEEVNITFIGNPGFVFVDHGGDIEVNCHSNYGEPRWSKTNFKSIEEITGAKQTYIQPNIAQLTIKSATYDARGYYNCSVRSPDSNRELARKLMFIHVHDLTCPEDNIKCDKNTKCIPKHKLCDNVMDCRDNSDEKNCTKCNFELEIKPKFILLSTAGWGNLQCIVPHKDCLPIQWITRNGDNLSPKNYIKYNHSLFMFNLEPQENQEIICTNGQKSTSAFLTVKYLDITIVPYQPDGSTLYINKGDTQIIECRSTLGTPQWIFPRLNLLSNFGVRYLTDEPNVAKILLTNVQENASGLYVCSVAFTRET Sbjct: 1 MTVNNVIIYFFLVYFNLKFIYPQITNGESRSKNVIDLHDGSGNGHENVNHHLNAKLLTLDDEDSMKTTNSKILQSSGDGQPEPPDMYPTLHPYAKSRSTATIIVDIAIESDFKSYMLPGSPFSSDLNAFYKKVIRNLQEELSQINVDLGFKIISLRPGPLISKRHSIKAPEAHSPSVFARINVTQYNSSIVNPMIIFHISHCGRLGILGNLTISDQVIFPLYVCPNDHVYCLPNCRKGTYCDGIVDCPSSNLDEAPSCPKCLYKTLQLTSNTEYLNEGENLVLSCNLKESCNELQNKIEWSFPGQLEKYQIRFRGERWINSLPKNKISSGIYKCHLDEKSAIKNITVFKRPDVFITNTVSNAVELIMTESYGSDINLWCNCSEGHAQWNNVESTNGYVNQMDREHSKLIIRSLSETTDVKCQVRWGFEERGNIMTSVRINVVCNPATHFQCKRFAGKMCIPISQKCDSITQCEDSSDEEECNYCSDKSLSISSGQNVFKERGDTLTMTCSSTMEACYPLIWLRFNKPLEMHRNLVVFKQSVFVFNISSIDTGIYRCSASSNKAFIDVSVNVIEPPTLKINYPSSVINITAGHDIDIICSITEPRASEKQTLRPIWKFDQSKLILNNIKLNYFPNRTSILSIVKATKDVESEYTCEVLWGLGYSKKSSITVRVNVIPLTCSYREKMCADKMKCIPSSMWCDGQKQCHDGSDEEVCNKCRNGFVIVQPSTLVILSRESTQVTCYYHKDCYPVEWRLAKDQQSVNSINGVSVMGNKLMLNNVGLEASKVYECFSGDKSSQINITVIEEVNITFIGNPGFVFVDHGGDIEVNCHSNYGEPRWSKTNFKSIEEITGAKQTYIQPNIAQLTIKSATYDARGYYNCSVRSPDSNRELARKLMFIHVHDLTCPEDNIKCDKNTKCIPKHKLCDNVMDCRDNSDEKNCTKCNFELEIKPKFILLSTAGWGNLQCIVPHKDCLPIQWITRNGDNLSPKNYIKYNHSLFMFNLEPQENQEIICTNGQKSTSAFLTVKYLDITIVPYQPDGSTLYINKGDTQIIECRSTLGTPQWIFPRLNLLSNFGVRYLTDEPNVAKILLTNVQENASGLYVCSVAFTRET 1111
BLAST of Ig-like domain-containing protein vs. Planmine SMEST
Match: SMESG000042512.1 (SMESG000042512.1) HSP 1 Score: 2230.29 bits (5778), Expect = 0.000e+0 Identity = 1083/1111 (97.48%), Postives = 1086/1111 (97.75%), Query Frame = 2 Query: 53 MTVNNVIIYFFLVYFNLKFIYPQITNGESRSKNVIDLHDGSGNGHENVNHHLNAKLMTLDDEDSMKTTNSKILQSSGDGQPEPPDMYPTLHPYAKSRSTATIIVDIAIESDFKSYMLPGSPFSSDLNAFYKKVIRNLQEELSQINVDLGFKIISLRPGPLISKRHSIKAPEAHSPSVFARINVTQYNSSIVNPMIIFHISHCGRLGILGNLTISDQVIFPLYVCPNDHVYCLPNCRKGTYCDGIVDCPSSNLDEAPSCPKCLYKTLQLTSNTEYLNEGENLVLSCNLKESCNELQNKIEWSFPGQLEKYQIRFRGERWINSLPKNKISSGIYKCHLDEESAIKNITVFKRPDVFITNTVSNAVELIMTESYGSDINLWCNCSEGHAQWNNVESTNGYVNQMDREHSKLIIRSLSETTDVKCQVRWGFEERGNIMTSVRINVVCNPATHFQCKRFAGKMCIPISQKCDSITQCEDSSDEEECNYCSDKSLSISSGQNVFKERGDTLTMTCSSTMEACYPLIWLRFNKPLEMHRNLVVFKQSVFVFNISSIDTGIYRCSASSNKAFIDVSVNVIEPPTLKINYPSSVINITAGHDIDIICSITENKASEKQTLRPIWKFDQSKLILNNIKLNYFPNRTSILSIVKATKDVESEYTCEVLWGLGYSKKSSITVRVNVIPLTCSYREKMCADKMKCIPSSMWCDGQKQCHDGSDEEVCNKCRNGFVIVQPSTLVILSRESTQVTCYYHKDCYPVEWRLAKDQQSVNSINGVSVMGNKLMLNNVGLEASKVYECFSGDKSSQINITVIEEVNITFIGNPGFVFVDHGGDIEVNCHSNYGEPRWSKTNFKSIEEITGAKQTYIQPNIAQLTIKSATYDARGYYNCSVRSPDSNRELARKLMFIHVHDLTCPEDNIKCDKNTKCIPKHKLCDNVMDCRDNSDEKNCTKCNFELEIKPKFILLSTAGWGNLQCIVPHKDCLPIQWITRNGDNLSPKNYIKYNHSLFMFNLEPQENQEIICTNGQKSTSAFLTVKYLDITIVPYQPDGSTLYINKGDTQIIECRSTLGTPQWIFPRLNLLSNFGVRYLTDEPNVAKILLTNVQENASGLYVCSVAFTRET 3385 MTVNNVIIYFFLVYFNLKFIYPQITNGESRSK +TLDDEDSMKTTNSKILQSSGDGQPEPPDMYPTLHPYAKSRSTATIIVDIAIESDFKSYMLPGSPFSSDLNAFYKKVIRNLQEELSQINVDLGFKIISLRPGPLISKRHSIKAPEAHSPSVFARINVTQYNSSIVNPMIIFHISHCGRLGILGNLTISDQVIFPLYVCPNDHVYCLPNCRKGTYCDGIVDCPSSNLDEAPSCPKCLYKTLQLTSNTEYLNEGENLVLSCNLKESCNELQNKIEWSFPGQLEKYQIRFRGERWINSLPKNKISSGIYKCHLDE+SAIKNITVFKRPDVFITNTVSNAVELIMTESYGSDINLWCNCSEGHAQWNNVESTNGYVNQMDREHSKLIIRSLSETTDVKCQVRWGFEERGNIMTSVRINVVCNPATHFQCKRFAGKMCIPISQKCDSITQCEDSSDEEECNYCSDKSLSISSGQNVFKERGDTLTMTCSSTMEACYPLIWLRFNKPLEMHRNLVVFKQSVFVFNISSIDTGIYRCSASSNKAFIDVSVNVIEPPTLKINYPSSVINITAGHDIDIICSITE +ASEKQTLRPIWKFDQSKLILNNIKLNYFPNRTSILSIVKATKDVESEYTCEVLWGLGYSKKSSITVRVNVIPLTCSYREKMCADKMKCIPSSMWCDGQKQCHDGSDEEVCNKCRNGFVIVQPSTLVILSRESTQVTCYYHKDCYPVEWRLAKDQQSVNSINGVSVMGNKLMLNNVGLEASKVYECFSGDKSSQINITVIEEVNITFIGNPGFVFVDHGGDIEVNCHSNYGEPRWSKTNFKSIEEITGAKQTYIQPNIAQLTIKSATYDARGYYNCSVRSPDSNRELARKLMFIHVHDLTCPEDNIKCDKNTKCIPKHKLCDNVMDCRDNSDEKNCTKCNFELEIKPKFILLSTAGWGNLQCIVPHKDCLPIQWITRNGDNLSPKNYIKYNHSLFMFNLEPQENQEIICTNGQKSTSAFLTVKYLDITIVPYQPDGSTLYINKGDTQIIECRSTLGTPQWIFPRLNLLSNFGVRYLTDEPNVAKILLTNVQENASGLYVCSVAFTRET Sbjct: 1 MTVNNVIIYFFLVYFNLKFIYPQITNGESRSK------------------------LTLDDEDSMKTTNSKILQSSGDGQPEPPDMYPTLHPYAKSRSTATIIVDIAIESDFKSYMLPGSPFSSDLNAFYKKVIRNLQEELSQINVDLGFKIISLRPGPLISKRHSIKAPEAHSPSVFARINVTQYNSSIVNPMIIFHISHCGRLGILGNLTISDQVIFPLYVCPNDHVYCLPNCRKGTYCDGIVDCPSSNLDEAPSCPKCLYKTLQLTSNTEYLNEGENLVLSCNLKESCNELQNKIEWSFPGQLEKYQIRFRGERWINSLPKNKISSGIYKCHLDEKSAIKNITVFKRPDVFITNTVSNAVELIMTESYGSDINLWCNCSEGHAQWNNVESTNGYVNQMDREHSKLIIRSLSETTDVKCQVRWGFEERGNIMTSVRINVVCNPATHFQCKRFAGKMCIPISQKCDSITQCEDSSDEEECNYCSDKSLSISSGQNVFKERGDTLTMTCSSTMEACYPLIWLRFNKPLEMHRNLVVFKQSVFVFNISSIDTGIYRCSASSNKAFIDVSVNVIEPPTLKINYPSSVINITAGHDIDIICSITEPRASEKQTLRPIWKFDQSKLILNNIKLNYFPNRTSILSIVKATKDVESEYTCEVLWGLGYSKKSSITVRVNVIPLTCSYREKMCADKMKCIPSSMWCDGQKQCHDGSDEEVCNKCRNGFVIVQPSTLVILSRESTQVTCYYHKDCYPVEWRLAKDQQSVNSINGVSVMGNKLMLNNVGLEASKVYECFSGDKSSQINITVIEEVNITFIGNPGFVFVDHGGDIEVNCHSNYGEPRWSKTNFKSIEEITGAKQTYIQPNIAQLTIKSATYDARGYYNCSVRSPDSNRELARKLMFIHVHDLTCPEDNIKCDKNTKCIPKHKLCDNVMDCRDNSDEKNCTKCNFELEIKPKFILLSTAGWGNLQCIVPHKDCLPIQWITRNGDNLSPKNYIKYNHSLFMFNLEPQENQEIICTNGQKSTSAFLTVKYLDITIVPYQPDGSTLYINKGDTQIIECRSTLGTPQWIFPRLNLLSNFGVRYLTDEPNVAKILLTNVQENASGLYVCSVAFTRET 1087
BLAST of Ig-like domain-containing protein vs. Planmine SMEST
Match: SMESG000026265.1 (SMESG000026265.1) HSP 1 Score: 51.6026 bits (122), Expect = 4.110e-6 Identity = 73/323 (22.60%), Postives = 132/323 (40.87%), Query Frame = 2 Query: 2150 DGQKQCHDG---SDEEVCNKCRNGFVIVQPSTLVILSRESTQVTC----YYHKDCYPVEWRLAKDQQSVN----------SINGVSVMGNKLMLNNVGLEASKVYECFSGDK-SSQINITVIEE---VNITFIGNPGFVFVDHGGDIEVNCHSN------YGEPRWSKTNFKSIEEITGAKQTYIQPNIAQLTI-KSATYDARGYYNCSVRSPDSNRELARKLMFIHVHDLTCPEDNIKCDKNTKCIPKHKLCDNVMDCRDNSDEKNCTKCNFELEIKPKFILLSTAGWGNLQCIVPHKDCLPIQWITRNGDNLSPKNYIKYN 3034 +G+ +C G + V +G ++ PS + ++ + C Y+ D + WR + +N + + ++ + + L+ + S EC SG+ ++Q + V+E+ NIT P + V E C YGEP++ K +E T + P+ ++T CSV N++++ ++I V + TCP + +C +N +C+P K CD + DC D SDE + T CN +P F ++ P + + WI +G+N NY + N Sbjct: 479 EGRYECRYGIVRKEATVMLDIDSGMIVTNPSKIKVIEGSPVEFHCRIDDVYNIDNRNLSWRFYNNNFQINYSLENSKWRLTESKIADHTSFINLDRATMADSGYIECISGNGLTAQSQLIVVEDKHKFNITV--TPNHLRVRKNQLFEFECFGQSDEGIPYGEPKFEFPGGKPVENDKRFLVTTVGPSRIRITAPHGVNIKDELKLICSV-----NKQVS--AVYIQVQE-TCPPNQRQC-QNRQCLPVGKFCDGIADCVDGSDE-DPTVCN---SCEPAFTTCQ-----DVYGFAPTRKTINKNWIC-DGENDCGNNYDEIN 780 The following BLAST results are available for this feature:
BLAST of Ig-like domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 0
BLAST of Ig-like domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of Ig-like domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of Ig-like domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 3
BLAST of Ig-like domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 1
BLAST of Ig-like domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 2
BLAST of Ig-like domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 1
BLAST of Ig-like domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Ig-like domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 0
BLAST of Ig-like domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of Ig-like domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Ig-like domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 0
BLAST of Ig-like domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 0
BLAST of Ig-like domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 3
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30021103 ID=SMED30021103|Name=Ig-like domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=3625bpback to top protein sequence of SMED30021103-orf-1 >SMED30021103-orf-1 ID=SMED30021103-orf-1|Name=SMED30021103-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1122bp MTVNNVIIYFFLVYFNLKFIYPQITNGESRSKNVIDLHDGSGNGHENVNHback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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