Thyroid hormone receptor interactor 11

Overview
NameThyroid hormone receptor interactor 11
Smed IDSMED30021093
Length (bp)1809
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Thyroid hormone receptor interactor 11 (SMED30021093) t-SNE clustered cells

Violin plots show distribution of expression levels for Thyroid hormone receptor interactor 11 (SMED30021093) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Thyroid hormone receptor interactor 11 (SMED30021093) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Thyroid hormone receptor interactor 11 (SMED30021093) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30021093

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 10

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X2 cellSMED30021093SMESG000037100.1 SmedASXL_006369SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
nervous systemSMED30021093SMESG000037100.1 dd_Smed_v4_3407_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30021093SMESG000037100.1 dd_Smed_v4_3407_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30021093SMESG000037100.1 dd_Smed_v4_3407_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30021093SMESG000037100.1 dd_Smed_v4_3407_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30021093SMESG000037101.1 SMESG000037100.1 Contig21145uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30021093SMESG000037101.1 SMESG000037100.1 Contig21145newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30021093SMESG000037100.1 Contig10465uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30021093SMESG000037100.1 Contig10465newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
epidermisSMED30021093SMESG000037100.1 dd_Smed_v4_3407_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Thyroid hormone receptor interactor 11 vs. Ensembl Human
Match: TRIP11 (thyroid hormone receptor interactor 11 [Source:HGNC Symbol;Acc:HGNC:12305])

HSP 1 Score: 131.339 bits (329), Expect = 4.672e-31
Identity = 88/244 (36.07%), Postives = 139/244 (56.97%), Query Frame = 2 
Query:  632 LSSEMNELRIERDAAKLQLGEAEVQLAENLRSLGNLQSVLEKFQQEQSLEMLYQKERFQQDIDRLIRERDSCAERNRSLQNEMDNQRDLVDAAQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKLNSFTESKVDKVLMKNLVIGYFHTPTHRRQEALKVIGSLLQFADSDYNQI-GIDTANRSRWF-NWL---RPSVGDKASGTDDRAVPGKSFSELFITFLENESSP-IPQVKLPTN 1345
            L  ++N +  +RD   LQL  ++ Q+ +   SL NLQ VLE FQQE+      + E+ +Q I    +  ++   +  SLQ  +D     +D+A RLT+Q++ K++Q+ EL+     R+E++D  + ++  L + +E KVDKVLM+NL IG+FHTP ++R E L+++GS+L     +  Q+   D    +RW   WL     SV +     + ++V   SFSELF+ FLE ES P IP  KL  +
Sbjct: 1641 LQEQLNVVSKQRDETALQLSVSQEQVKQYALSLANLQMVLEHFQQEEKAMYSAELEKQKQLIAEWKKNAENLEGKVISLQECLDEANAALDSASRLTEQLDVKEEQIEELKRQNELRQEMLDDVQKKLMSLANSSEGKVDKVLMRNLFIGHFHTPKNQRHEVLRLMGSILGVRREEMEQLFHDDQGGVTRWMTGWLGGGSKSVPNTPLRPNQQSVVNSSFSELFVKFLETESHPSIPPPKLSVH 1884
[Close]
BLAST of Thyroid hormone receptor interactor 11 vs. Ensembl Human
Match: TRIP11 (thyroid hormone receptor interactor 11 [Source:HGNC Symbol;Acc:HGNC:12305])

HSP 1 Score: 130.954 bits (328), Expect = 5.652e-31
Identity = 88/244 (36.07%), Postives = 139/244 (56.97%), Query Frame = 2 
Query:  632 LSSEMNELRIERDAAKLQLGEAEVQLAENLRSLGNLQSVLEKFQQEQSLEMLYQKERFQQDIDRLIRERDSCAERNRSLQNEMDNQRDLVDAAQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKLNSFTESKVDKVLMKNLVIGYFHTPTHRRQEALKVIGSLLQFADSDYNQI-GIDTANRSRWF-NWL---RPSVGDKASGTDDRAVPGKSFSELFITFLENESSP-IPQVKLPTN 1345
            L  ++N +  +RD   LQL  ++ Q+ +   SL NLQ VLE FQQE+      + E+ +Q I    +  ++   +  SLQ  +D     +D+A RLT+Q++ K++Q+ EL+     R+E++D  + ++  L + +E KVDKVLM+NL IG+FHTP ++R E L+++GS+L     +  Q+   D    +RW   WL     SV +     + ++V   SFSELF+ FLE ES P IP  KL  +
Sbjct: 1357 LQEQLNVVSKQRDETALQLSVSQEQVKQYALSLANLQMVLEHFQQEEKAMYSAELEKQKQLIAEWKKNAENLEGKVISLQECLDEANAALDSASRLTEQLDVKEEQIEELKRQNELRQEMLDDVQKKLMSLANSSEGKVDKVLMRNLFIGHFHTPKNQRHEVLRLMGSILGVRREEMEQLFHDDQGGVTRWMTGWLGGGSKSVPNTPLRPNQQSVVNSSFSELFVKFLETESHPSIPPPKLSVH 1600
[Close]
BLAST of Thyroid hormone receptor interactor 11 vs. Ensembl Human
Match: TRIP11 (thyroid hormone receptor interactor 11 [Source:HGNC Symbol;Acc:HGNC:12305])

HSP 1 Score: 48.521 bits (114), Expect = 5.724e-6
Identity = 42/115 (36.52%), Postives = 66/115 (57.39%), Query Frame = 2 
Query:  632 LSSEMNELRIERDAAKLQLGEAEVQLAENLRSLGNLQSVLEKFQQEQSLEMLYQKERFQQDIDRLIRERDSCAE----RNRSLQNEMDNQRDLVDAAQRLTDQIEHKDDQLAELQ 964
            L  ++N +  +RD   LQL  ++ Q+ +   SL NLQ VLE FQQE+  + +Y  E  +Q   +LI E    AE    +  SLQ  +D     +D+A RLT+Q++ K++Q+ EL+
Sbjct:   57 LQEQLNVVSKQRDETALQLSVSQEQVKQYALSLANLQMVLEHFQQEE--KAMYSAELEKQ--KQLIAEWKKNAENLEGKVISLQECLDEANAALDSASRLTEQLDVKEEQIEELK 167
[Close]
BLAST of Thyroid hormone receptor interactor 11 vs. Ensembl Fly
Match: Gmap (gene:FBgn0027287 transcript:FBtr0474150)

HSP 1 Score: 60.077 bits (144), Expect = 5.511e-9
Identity = 67/237 (28.27%), Postives = 113/237 (47.68%), Query Frame = 2 
Query:  665 RDAAKLQLGEAEVQLAENLRSLGNLQSVLEKFQ--QEQSLEMLYQKERFQQDIDRLIRERDSCAERNRSLQNEMDN-QRDLVDA------AQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKLNSFTESKVDKVLMKNLVIGYFHTP-THRRQEALKVIGSLLQFADSDYNQIGIDTANRSRWFNW-LRPSVGDKASGTDDRAVPGKSFSELFITFLENESSPIPQVKLPT 1342
            RD    +LG+ E +  +   +L NLQ  LE+FQ  ++  +EM  Q         R+ RE  +  +R   LQ EM   Q+ L +A      A RL+DQ+E     +A L+  +   +E     +  +    S    K+DK L+K+L+IGY  +     +Q+ L++I S+L F   + +++G++   +S W    L       ++    R    ++  + F+ FLE ES P  Q + PT
Sbjct: 1090 RDELLAKLGQYEDRELKQQAALTNLQCALEQFQNDKDHDIEMATQ---------RIRREMQAQLDRQGQLQLEMSGLQQQLAEANQGLRAAARLSDQLEAGQQTIAVLRDEVESLKEANGQLEQRLSSSESSQTDKIDKSLIKSLLIGYVVSGHAGDKQQVLRMISSVLDFNAQEADKVGLNK-QQSSWLGAILGGGSATASAAGSSRG--NENLVQAFVQFLEQESQPQAQSR-PT 1313
[Close]
BLAST of Thyroid hormone receptor interactor 11 vs. Ensembl Fly
Match: Gmap (gene:FBgn0027287 transcript:FBtr0074042)

HSP 1 Score: 60.077 bits (144), Expect = 5.603e-9
Identity = 67/237 (28.27%), Postives = 113/237 (47.68%), Query Frame = 2 
Query:  665 RDAAKLQLGEAEVQLAENLRSLGNLQSVLEKFQ--QEQSLEMLYQKERFQQDIDRLIRERDSCAERNRSLQNEMDN-QRDLVDA------AQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKLNSFTESKVDKVLMKNLVIGYFHTP-THRRQEALKVIGSLLQFADSDYNQIGIDTANRSRWFNW-LRPSVGDKASGTDDRAVPGKSFSELFITFLENESSPIPQVKLPT 1342
            RD    +LG+ E +  +   +L NLQ  LE+FQ  ++  +EM  Q         R+ RE  +  +R   LQ EM   Q+ L +A      A RL+DQ+E     +A L+  +   +E     +  +    S    K+DK L+K+L+IGY  +     +Q+ L++I S+L F   + +++G++   +S W    L       ++    R    ++  + F+ FLE ES P  Q + PT
Sbjct: 1090 RDELLAKLGQYEDRELKQQAALTNLQCALEQFQNDKDHDIEMATQ---------RIRREMQAQLDRQGQLQLEMSGLQQQLAEANQGLRAAARLSDQLEAGQQTIAVLRDEVESLKEANGQLEQRLSSSESSQTDKIDKSLIKSLLIGYVVSGHAGDKQQVLRMISSVLDFNAQEADKVGLNK-QQSSWLGAILGGGSATASAAGSSRG--NENLVQAFVQFLEQESQPQAQSR-PT 1313
[Close]
BLAST of Thyroid hormone receptor interactor 11 vs. Ensembl Fly
Match: Gmap (gene:FBgn0027287 transcript:FBtr0074043)

HSP 1 Score: 59.6918 bits (143), Expect = 6.442e-9
Identity = 67/237 (28.27%), Postives = 113/237 (47.68%), Query Frame = 2 
Query:  665 RDAAKLQLGEAEVQLAENLRSLGNLQSVLEKFQ--QEQSLEMLYQKERFQQDIDRLIRERDSCAERNRSLQNEMDN-QRDLVDA------AQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKLNSFTESKVDKVLMKNLVIGYFHTP-THRRQEALKVIGSLLQFADSDYNQIGIDTANRSRWFNW-LRPSVGDKASGTDDRAVPGKSFSELFITFLENESSPIPQVKLPT 1342
            RD    +LG+ E +  +   +L NLQ  LE+FQ  ++  +EM  Q         R+ RE  +  +R   LQ EM   Q+ L +A      A RL+DQ+E     +A L+  +   +E     +  +    S    K+DK L+K+L+IGY  +     +Q+ L++I S+L F   + +++G++   +S W    L       ++    R    ++  + F+ FLE ES P  Q + PT
Sbjct:  900 RDELLAKLGQYEDRELKQQAALTNLQCALEQFQNDKDHDIEMATQ---------RIRREMQAQLDRQGQLQLEMSGLQQQLAEANQGLRAAARLSDQLEAGQQTIAVLRDEVESLKEANGQLEQRLSSSESSQTDKIDKSLIKSLLIGYVVSGHAGDKQQVLRMISSVLDFNAQEADKVGLNK-QQSSWLGAILGGGSATASAAGSSRG--NENLVQAFVQFLEQESQPQAQSR-PT 1123
[Close]
BLAST of Thyroid hormone receptor interactor 11 vs. Ensembl Fly
Match: Gmap (gene:FBgn0027287 transcript:FBtr0343525)

HSP 1 Score: 59.6918 bits (143), Expect = 6.442e-9
Identity = 67/237 (28.27%), Postives = 113/237 (47.68%), Query Frame = 2 
Query:  665 RDAAKLQLGEAEVQLAENLRSLGNLQSVLEKFQ--QEQSLEMLYQKERFQQDIDRLIRERDSCAERNRSLQNEMDN-QRDLVDA------AQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKLNSFTESKVDKVLMKNLVIGYFHTP-THRRQEALKVIGSLLQFADSDYNQIGIDTANRSRWFNW-LRPSVGDKASGTDDRAVPGKSFSELFITFLENESSPIPQVKLPT 1342
            RD    +LG+ E +  +   +L NLQ  LE+FQ  ++  +EM  Q         R+ RE  +  +R   LQ EM   Q+ L +A      A RL+DQ+E     +A L+  +   +E     +  +    S    K+DK L+K+L+IGY  +     +Q+ L++I S+L F   + +++G++   +S W    L       ++    R    ++  + F+ FLE ES P  Q + PT
Sbjct:  900 RDELLAKLGQYEDRELKQQAALTNLQCALEQFQNDKDHDIEMATQ---------RIRREMQAQLDRQGQLQLEMSGLQQQLAEANQGLRAAARLSDQLEAGQQTIAVLRDEVESLKEANGQLEQRLSSSESSQTDKIDKSLIKSLLIGYVVSGHAGDKQQVLRMISSVLDFNAQEADKVGLNK-QQSSWLGAILGGGSATASAAGSSRG--NENLVQAFVQFLEQESQPQAQSR-PT 1123
[Close]
BLAST of Thyroid hormone receptor interactor 11 vs. Ensembl Zebrafish
Match: trip11 (thyroid hormone receptor interactor 11 [Source:ZFIN;Acc:ZDB-GENE-030131-9833])

HSP 1 Score: 127.487 bits (319), Expect = 2.738e-30
Identity = 86/251 (34.26%), Postives = 143/251 (56.97%), Query Frame = 2 
Query:  632 LSSEMNELRIERDAAKLQLGEAEVQLAENLRSLGNLQSVLEKFQQEQSLEMLYQKERFQQDIDRLIRERDSCAERNRSLQNEMDNQRDLVDAAQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKLNSFTESKVDKVLMKNLVIGYFHTPTHRRQEALKVIGSLLQFADSDYNQIG--IDTANRSRWFNWLRPSVGDKA----SGTDDRAVPGK----SFSELFITFLENESSP-IPQVKLPTNQI 1351
            L  ++N    +RD A +QL  ++ Q+ +   SL NLQ VLE+FQQE+      + E+ +++      + +S  E   +L+  +D     +++A RLTDQ++ KD+Q+ +L   +  R+E+++  + ++  L + TE KVDKVLMKNL +GYFHTP ++R E L+++G++L     D +++G  +    +S    W+   +G +A      T  R    +    SFSE+F+ FLE ESSP +P  KLP   I
Sbjct:  372 LQEQLNGAVRQRDEALIQLRASQDQVNQYAVSLSNLQMVLEQFQQEEKAMYSAELEKHKREKMEWRNKAESLEEIAAALRINLDEANAALESASRLTDQLDLKDEQIEDLNKQVEVRQEMLEEAQRKLMNLLNTTEGKVDKVLMKNLYLGYFHTPQNKRGEVLRLMGNVLGL---DRDEVGQLLKEEVKSGMTGWVSSWLGGRAVQSVPNTPQRPTQAQSLNSSFSEMFVKFLEVESSPALPAPKLPMYDI 619
[Close]
BLAST of Thyroid hormone receptor interactor 11 vs. Ensembl Zebrafish
Match: trip11 (thyroid hormone receptor interactor 11 [Source:ZFIN;Acc:ZDB-GENE-030131-9833])

HSP 1 Score: 126.331 bits (316), Expect = 1.340e-29
Identity = 88/258 (34.11%), Postives = 145/258 (56.20%), Query Frame = 2 
Query:  632 LSSEMNELRIERDAAKLQLGEAEVQLAENLRSLGNLQSVLEKFQQEQSLEMLYQKERFQQDIDRLIRER-------DSCAERNRSLQNEMDNQRDLVDAAQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKLNSFTESKVDKVLMKNLVIGYFHTPTHRRQEALKVIGSLLQFADSDYNQIG--IDTANRSRWFNWLRPSVGDKA----SGTDDRAVPGK----SFSELFITFLENESSP-IPQVKLPTNQI 1351
            L  ++N    +RD A +QL  ++ Q+ +   SL NLQ VLE+FQQE+       K  +  ++++  RE+       +S  E   +L+  +D     +++A RLTDQ++ KD+Q+ +L   +  R+E+++  + ++  L + TE KVDKVLMKNL +GYFHTP ++R E L+++G++L     D +++G  +    +S    W+   +G +A      T  R    +    SFSE+F+ FLE ESSP +P  KLP   I
Sbjct: 1612 LQEQLNGAVRQRDEALIQLRASQDQVNQYAVSLSNLQMVLEQFQQEE-------KAMYSAELEKHKREKMEWRNKAESLEEIAAALRINLDEANAALESASRLTDQLDLKDEQIEDLNKQVEVRQEMLEEAQRKLMNLLNTTEGKVDKVLMKNLYLGYFHTPQNKRGEVLRLMGNVLGL---DRDEVGQLLKEEVKSGMTGWVSSWLGGRAVQSVPNTPQRPTQAQSLNSSFSEMFVKFLEVESSPALPAPKLPMYDI 1859
[Close]
BLAST of Thyroid hormone receptor interactor 11 vs. Ensembl Zebrafish
Match: trip11 (thyroid hormone receptor interactor 11 [Source:ZFIN;Acc:ZDB-GENE-030131-9833])

HSP 1 Score: 126.331 bits (316), Expect = 1.485e-29
Identity = 88/258 (34.11%), Postives = 145/258 (56.20%), Query Frame = 2 
Query:  632 LSSEMNELRIERDAAKLQLGEAEVQLAENLRSLGNLQSVLEKFQQEQSLEMLYQKERFQQDIDRLIRER-------DSCAERNRSLQNEMDNQRDLVDAAQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKLNSFTESKVDKVLMKNLVIGYFHTPTHRRQEALKVIGSLLQFADSDYNQIG--IDTANRSRWFNWLRPSVGDKA----SGTDDRAVPGK----SFSELFITFLENESSP-IPQVKLPTNQI 1351
            L  ++N    +RD A +QL  ++ Q+ +   SL NLQ VLE+FQQE+       K  +  ++++  RE+       +S  E   +L+  +D     +++A RLTDQ++ KD+Q+ +L   +  R+E+++  + ++  L + TE KVDKVLMKNL +GYFHTP ++R E L+++G++L     D +++G  +    +S    W+   +G +A      T  R    +    SFSE+F+ FLE ESSP +P  KLP   I
Sbjct: 1645 LQEQLNGAVRQRDEALIQLRASQDQVNQYAVSLSNLQMVLEQFQQEE-------KAMYSAELEKHKREKMEWRNKAESLEEIAAALRINLDEANAALESASRLTDQLDLKDEQIEDLNKQVEVRQEMLEEAQRKLMNLLNTTEGKVDKVLMKNLYLGYFHTPQNKRGEVLRLMGNVLGL---DRDEVGQLLKEEVKSGMTGWVSSWLGGRAVQSVPNTPQRPTQAQSLNSSFSEMFVKFLEVESSPALPAPKLPMYDI 1892
[Close]
BLAST of Thyroid hormone receptor interactor 11 vs. Ensembl Xenopus
Match: smc2 (structural maintenance of chromosomes 2 [Source:Xenbase;Acc:XB-GENE-5826169])

HSP 1 Score: 124.02 bits (310), Expect = 8.912e-29
Identity = 84/263 (31.94%), Postives = 147/263 (55.89%), Query Frame = 2 
Query:  662 ERDAAKLQLGEAEVQLAENLRSLGNLQSVLEKFQQEQSLEMLYQKERFQQDIDRLIRERDSCAERNRSLQNEMDNQRDLVDAAQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKLNSFTESKVDKVLMKNLVIGYFHTPTHRRQEALKVIGSLLQFADSDYNQIGIDTA-NRSRWF-NWLRPSVGDKASGTDDR----AVPGKSFSELFITFLENESSPI-PQVKLPTNQITAEARQHSSLSQSDEYPYTHSTSLTS 1429
            +RD A LQ   ++ Q  +   SL NLQ VLE+FQQE+      + E+ ++    L ++ +    +  SL+ ++D     +++A RLT+Q++ K++ + EL+     ++E+++  + ++  L + TE KVDKVLM+NL +G+FHTP ++R E L+++GS+L     + +++ +D     SRW   WL          T  R    ++   SFSELF+ FLE ES P  P +KL   ++T  +R  S+L+ S     + + ++ S
Sbjct: 1629 QRDEALLQFNLSQEQCKQYALSLANLQMVLEQFQQEEKAMYSAELEKHKKQACELKQKVEILENKALSLKEKLDEANVALESASRLTEQLDIKEELIEELKRQGDLKQEMLEDAQNKLMNLLNSTEGKVDKVLMRNLFVGHFHTPKNKRHEVLRLMGSILGIKKEEMDELVVDEHRGVSRWMTGWLGGGGSKSVPSTPQRPNHPSLFNTSFSELFVKFLETESHPTPPPLKLTMQELTP-SRPASTLNPSGSLATSVAGTMVS 1890
[Close]
BLAST of Thyroid hormone receptor interactor 11 vs. Ensembl Xenopus
Match: smc2 (structural maintenance of chromosomes 2 [Source:Xenbase;Acc:XB-GENE-5826169])

HSP 1 Score: 124.02 bits (310), Expect = 1.165e-28
Identity = 84/263 (31.94%), Postives = 147/263 (55.89%), Query Frame = 2 
Query:  662 ERDAAKLQLGEAEVQLAENLRSLGNLQSVLEKFQQEQSLEMLYQKERFQQDIDRLIRERDSCAERNRSLQNEMDNQRDLVDAAQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKLNSFTESKVDKVLMKNLVIGYFHTPTHRRQEALKVIGSLLQFADSDYNQIGIDTA-NRSRWF-NWLRPSVGDKASGTDDR----AVPGKSFSELFITFLENESSPI-PQVKLPTNQITAEARQHSSLSQSDEYPYTHSTSLTS 1429
            +RD A LQ   ++ Q  +   SL NLQ VLE+FQQE+      + E+ ++    L ++ +    +  SL+ ++D     +++A RLT+Q++ K++ + EL+     ++E+++  + ++  L + TE KVDKVLM+NL +G+FHTP ++R E L+++GS+L     + +++ +D     SRW   WL          T  R    ++   SFSELF+ FLE ES P  P +KL   ++T  +R  S+L+ S     + + ++ S
Sbjct: 1579 QRDEALLQFNLSQEQCKQYALSLANLQMVLEQFQQEEKAMYSAELEKHKKQACELKQKVEILENKALSLKEKLDEANVALESASRLTEQLDIKEELIEELKRQGDLKQEMLEDAQNKLMNLLNSTEGKVDKVLMRNLFVGHFHTPKNKRHEVLRLMGSILGIKKEEMDELVVDEHRGVSRWMTGWLGGGGSKSVPSTPQRPNHPSLFNTSFSELFVKFLETESHPTPPPLKLTMQELTP-SRPASTLNPSGSLATSVAGTMVS 1840
[Close]
BLAST of Thyroid hormone receptor interactor 11 vs. Ensembl Xenopus
Match: smc2 (structural maintenance of chromosomes 2 [Source:Xenbase;Acc:XB-GENE-5826169])

HSP 1 Score: 123.635 bits (309), Expect = 1.240e-28
Identity = 79/238 (33.19%), Postives = 135/238 (56.72%), Query Frame = 2 
Query:  662 ERDAAKLQLGEAEVQLAENLRSLGNLQSVLEKFQQEQSLEMLYQKERFQQDIDRLIRERDSCAERNRSLQNEMDNQRDLVDAAQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKLNSFTESKVDKVLMKNLVIGYFHTPTHRRQEALKVIGSLLQFADSDYNQIGIDTA-NRSRWF-NWLRPSVGDKASGTDDR----AVPGKSFSELFITFLENESSPI-PQVKLPTNQIT 1354
            +RD A LQ   ++ Q  +   SL NLQ VLE+FQQE+      + E+ ++    L ++ +    +  SL+ ++D     +++A RLT+Q++ K++ + EL+     ++E+++  + ++  L + TE KVDKVLM+NL +G+FHTP ++R E L+++GS+L     + +++ +D     SRW   WL          T  R    ++   SFSELF+ FLE ES P  P +KL   ++T
Sbjct: 1588 QRDEALLQFNLSQEQCKQYALSLANLQMVLEQFQQEEKAMYSAELEKHKKQACELKQKVEILENKALSLKEKLDEANVALESASRLTEQLDIKEELIEELKRQGDLKQEMLEDAQNKLMNLLNSTEGKVDKVLMRNLFVGHFHTPKNKRHEVLRLMGSILGIKKEEMDELVVDEHRGVSRWMTGWLGGGGSKSVPSTPQRPNHPSLFNTSFSELFVKFLETESHPTPPPLKLTMQELT 1825
[Close]
BLAST of Thyroid hormone receptor interactor 11 vs. Ensembl Xenopus
Match: smc2 (structural maintenance of chromosomes 2 [Source:Xenbase;Acc:XB-GENE-5826169])

HSP 1 Score: 123.635 bits (309), Expect = 1.300e-28
Identity = 79/238 (33.19%), Postives = 135/238 (56.72%), Query Frame = 2 
Query:  662 ERDAAKLQLGEAEVQLAENLRSLGNLQSVLEKFQQEQSLEMLYQKERFQQDIDRLIRERDSCAERNRSLQNEMDNQRDLVDAAQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKLNSFTESKVDKVLMKNLVIGYFHTPTHRRQEALKVIGSLLQFADSDYNQIGIDTA-NRSRWF-NWLRPSVGDKASGTDDR----AVPGKSFSELFITFLENESSPI-PQVKLPTNQIT 1354
            +RD A LQ   ++ Q  +   SL NLQ VLE+FQQE+      + E+ ++    L ++ +    +  SL+ ++D     +++A RLT+Q++ K++ + EL+     ++E+++  + ++  L + TE KVDKVLM+NL +G+FHTP ++R E L+++GS+L     + +++ +D     SRW   WL          T  R    ++   SFSELF+ FLE ES P  P +KL   ++T
Sbjct: 1607 QRDEALLQFNLSQEQCKQYALSLANLQMVLEQFQQEEKAMYSAELEKHKKQACELKQKVEILENKALSLKEKLDEANVALESASRLTEQLDIKEELIEELKRQGDLKQEMLEDAQNKLMNLLNSTEGKVDKVLMRNLFVGHFHTPKNKRHEVLRLMGSILGIKKEEMDELVVDEHRGVSRWMTGWLGGGGSKSVPSTPQRPNHPSLFNTSFSELFVKFLETESHPTPPPLKLTMQELT 1844
[Close]
BLAST of Thyroid hormone receptor interactor 11 vs. Ensembl Xenopus
Match: smc2 (structural maintenance of chromosomes 2 [Source:Xenbase;Acc:XB-GENE-5826169])

HSP 1 Score: 123.635 bits (309), Expect = 1.487e-28
Identity = 79/238 (33.19%), Postives = 135/238 (56.72%), Query Frame = 2 
Query:  662 ERDAAKLQLGEAEVQLAENLRSLGNLQSVLEKFQQEQSLEMLYQKERFQQDIDRLIRERDSCAERNRSLQNEMDNQRDLVDAAQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKLNSFTESKVDKVLMKNLVIGYFHTPTHRRQEALKVIGSLLQFADSDYNQIGIDTA-NRSRWF-NWLRPSVGDKASGTDDR----AVPGKSFSELFITFLENESSPI-PQVKLPTNQIT 1354
            +RD A LQ   ++ Q  +   SL NLQ VLE+FQQE+      + E+ ++    L ++ +    +  SL+ ++D     +++A RLT+Q++ K++ + EL+     ++E+++  + ++  L + TE KVDKVLM+NL +G+FHTP ++R E L+++GS+L     + +++ +D     SRW   WL          T  R    ++   SFSELF+ FLE ES P  P +KL   ++T
Sbjct: 1559 QRDEALLQFNLSQEQCKQYALSLANLQMVLEQFQQEEKAMYSAELEKHKKQACELKQKVEILENKALSLKEKLDEANVALESASRLTEQLDIKEELIEELKRQGDLKQEMLEDAQNKLMNLLNSTEGKVDKVLMRNLFVGHFHTPKNKRHEVLRLMGSILGIKKEEMDELVVDEHRGVSRWMTGWLGGGGSKSVPSTPQRPNHPSLFNTSFSELFVKFLETESHPTPPPLKLTMQELT 1796
[Close]
BLAST of Thyroid hormone receptor interactor 11 vs. Ensembl Mouse
Match: Trip11 (thyroid hormone receptor interactor 11 [Source:MGI Symbol;Acc:MGI:1924393])

HSP 1 Score: 134.42 bits (337), Expect = 3.450e-32
Identity = 89/246 (36.18%), Postives = 141/246 (57.32%), Query Frame = 2 
Query:  632 LSSEMNELRIERDAAKLQLGEAEVQLAENLRSLGNLQSVLEKFQQEQSLEMLYQKERFQQD--IDRLIRERDSCAERNRSLQNEMDNQRDLVDAAQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKLNSFTESKVDKVLMKNLVIGYFHTPTHRRQEALKVIGSLLQFADSDYNQI-GIDTANRSRWF-NWL---RPSVGDKASGTDDRAVPGKSFSELFITFLENESSP-IPQVKLPTN 1345
            L  ++N +  +RD   LQL  ++ Q+ +   SL NLQ VLE FQQE+  + +Y  E  +Q+  +    ++ +S   +  SLQ  +D     +D+A RLT+Q++ K++Q+ EL+      +E++D  + ++  L + TE KVDKVLM+NL IG+FHTP H+R E L+++GS+L     +  Q+   D    +RW   WL     SV +     + ++V   SFSELF+ FLE ES P +P  KL  +
Sbjct: 1353 LQEQLNMVSKQRDETALQLSVSQEQVKQYALSLANLQMVLEHFQQEE--KAMYSAELEKQNHLLAEWKKKAESLEGKVLSLQERLDEANAALDSASRLTEQLDLKEEQIEELKKQNELHQEMLDDAQKKLMSLVNSTEGKVDKVLMRNLFIGHFHTPKHQRHEVLRLMGSILGVKREEMEQLFAEDQGGVTRWMAGWLGGGSKSVPNTPLRPNQQSVFNSSFSELFVKFLETESHPSVPPPKLSVH 1596
[Close]
BLAST of Thyroid hormone receptor interactor 11 vs. Ensembl Mouse
Match: Trip11 (thyroid hormone receptor interactor 11 [Source:MGI Symbol;Acc:MGI:1924393])

HSP 1 Score: 134.035 bits (336), Expect = 4.234e-32
Identity = 89/246 (36.18%), Postives = 141/246 (57.32%), Query Frame = 2 
Query:  632 LSSEMNELRIERDAAKLQLGEAEVQLAENLRSLGNLQSVLEKFQQEQSLEMLYQKERFQQD--IDRLIRERDSCAERNRSLQNEMDNQRDLVDAAQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKLNSFTESKVDKVLMKNLVIGYFHTPTHRRQEALKVIGSLLQFADSDYNQI-GIDTANRSRWF-NWL---RPSVGDKASGTDDRAVPGKSFSELFITFLENESSP-IPQVKLPTN 1345
            L  ++N +  +RD   LQL  ++ Q+ +   SL NLQ VLE FQQE+  + +Y  E  +Q+  +    ++ +S   +  SLQ  +D     +D+A RLT+Q++ K++Q+ EL+      +E++D  + ++  L + TE KVDKVLM+NL IG+FHTP H+R E L+++GS+L     +  Q+   D    +RW   WL     SV +     + ++V   SFSELF+ FLE ES P +P  KL  +
Sbjct: 1638 LQEQLNMVSKQRDETALQLSVSQEQVKQYALSLANLQMVLEHFQQEE--KAMYSAELEKQNHLLAEWKKKAESLEGKVLSLQERLDEANAALDSASRLTEQLDLKEEQIEELKKQNELHQEMLDDAQKKLMSLVNSTEGKVDKVLMRNLFIGHFHTPKHQRHEVLRLMGSILGVKREEMEQLFAEDQGGVTRWMAGWLGGGSKSVPNTPLRPNQQSVFNSSFSELFVKFLETESHPSVPPPKLSVH 1881
[Close]
BLAST of Thyroid hormone receptor interactor 11 vs. UniProt/SwissProt
Match: sp|Q15643|TRIPB_HUMAN (Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3)

HSP 1 Score: 131.339 bits (329), Expect = 2.244e-30
Identity = 88/244 (36.07%), Postives = 139/244 (56.97%), Query Frame = 2 
Query:  632 LSSEMNELRIERDAAKLQLGEAEVQLAENLRSLGNLQSVLEKFQQEQSLEMLYQKERFQQDIDRLIRERDSCAERNRSLQNEMDNQRDLVDAAQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKLNSFTESKVDKVLMKNLVIGYFHTPTHRRQEALKVIGSLLQFADSDYNQI-GIDTANRSRWF-NWL---RPSVGDKASGTDDRAVPGKSFSELFITFLENESSP-IPQVKLPTN 1345
            L  ++N +  +RD   LQL  ++ Q+ +   SL NLQ VLE FQQE+      + E+ +Q I    +  ++   +  SLQ  +D     +D+A RLT+Q++ K++Q+ EL+     R+E++D  + ++  L + +E KVDKVLM+NL IG+FHTP ++R E L+++GS+L     +  Q+   D    +RW   WL     SV +     + ++V   SFSELF+ FLE ES P IP  KL  +
Sbjct: 1641 LQEQLNVVSKQRDETALQLSVSQEQVKQYALSLANLQMVLEHFQQEEKAMYSAELEKQKQLIAEWKKNAENLEGKVISLQECLDEANAALDSASRLTEQLDVKEEQIEELKRQNELRQEMLDDVQKKLMSLANSSEGKVDKVLMRNLFIGHFHTPKNQRHEVLRLMGSILGVRREEMEQLFHDDQGGVTRWMTGWLGGGSKSVPNTPLRPNQQSVVNSSFSELFVKFLETESHPSIPPPKLSVH 1884
[Close]
BLAST of Thyroid hormone receptor interactor 11 vs. TrEMBL
Match: A0A3R7FXB0 (Thyroid receptor-interacting protein 11 (Fragment) OS=Clonorchis sinensis OX=79923 GN=TRIP11 PE=4 SV=1)

HSP 1 Score: 144.05 bits (362), Expect = 8.203e-34
Identity = 94/276 (34.06%), Postives = 153/276 (55.43%), Query Frame = 2 
Query:  593 TKLQRIIANIRSELSSEMNELRI-----ERDAAKLQLGEAEVQLAENLRSLGNLQSVLEKFQQEQSLEMLYQKERFQQDIDRL-IRERDSCAERNRSLQNEMDNQRDLVDAAQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKLNSFTESKVDKVLMKNLVIGYFHTPTHRRQEALKVIGSLLQFADSDYNQIGIDTANRSRWFNWLRPSVGDKASG-----TDDRAVPGKSFSELFITFLENESSPIPQVKLPTNQITAEARQHSSLSQ 1387
            T+LQ++      E SS+  E R+     ERD A+    E   +++    SLGNLQSVL+ FQQ Q   +  + E  + ++ R   RE  +CAE NR L  ++ ++  L   A  L  QI+H   QLA+L+  + +R+  ID  +  + ++   T+SK+DKVL++NL++ +F  P+ +R   L+VIGSLL F++ DY ++G ++    R   W+R +V     G     T     P K+F+EL ++FLE ES P   ++L  +  T +A + S+ +Q
Sbjct: 1145 TRLQQL------EESSQTVEDRVQRYMAERDEARTDAAEYRKEISALRASLGNLQSVLDSFQQSQQSTIQCETEHIRMELQRARHREEAACAEVNR-LNGQLSDRIVLEQRAHHLDLQIQHHATQLAQLREQIEQRDSQIDALRTRLAQMAVDTDSKIDKVLIRNLLVSFFQLPSSQRSSGLRVIGSLLDFSNDDYAKVGSESGALPRLLGWVRSAVSSFPPGPPKDVTLSSTYPDKTFTELLLSFLEQESGPRAPLRLSMDHYTPDAVRPSASAQ 1413

HSP 2 Score: 31.187 bits (69), Expect = 8.203e-34
Identity = 16/27 (59.26%), Postives = 18/27 (66.67%), Query Frame = 1 
Query:  463 FQDHLIRIEESYTQEATLAEDREQSLR 543
             Q HL+ +EESYT EA  AE RE  LR
Sbjct: 1111 LQAHLLEMEESYTTEALNAEAREVDLR 1137
[Close]
BLAST of Thyroid hormone receptor interactor 11 vs. TrEMBL
Match: A0A401NHT3 (GRIP domain-containing protein (Fragment) OS=Scyliorhinus torazame OX=75743 GN=scyTo_0012740 PE=4 SV=1)

HSP 1 Score: 134.035 bits (336), Expect = 9.741e-34
Identity = 88/289 (30.45%), Postives = 159/289 (55.02%), Query Frame = 2 
Query:  662 ERDAAKLQLGEAEVQLAENLRSLGNLQSVLEKFQQEQSLEMLYQKERFQQDIDRLIRERDSCAERNRSLQNEMDNQRDLVDAAQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKLNSFTESKVDKVLMKNLVIGYFHTPTHRRQEALKVIGSLLQFADSDYNQIGIDTANRSRWFNWLRPSVG-DKASGT----------DDRAVPGKSFSELFITFLENESSP-IPQVKLPTNQITAEARQHSSLSQSDEYPYTHSTSLTSIIDHHKFFPASPVVTKRNGSP 1492
            +RD A +QL  ++ Q+ +   SL NLQ V+E+FQQE+      + E++Q+DI    ++  S  +    L+  +    D +D+A RL +Q++ K++QL +L+  +  + ++++  + ++  L + +E ++DKVLM+NL +GYFHTP  +R EA++++G +L+    + +Q+ +D  NR     W+   +G ++ SGT          + R +   SFSE+F+ FLE ES P +P +KLP   +      HS  + S       S+  ++ I  H   P+   V K + +P
Sbjct: 1370 QRDEAVMQLNTSQEQVKQYAMSLTNLQMVIEQFQQEEKAMYATELEKYQKDIAEWKKKVSSLEKTVTELEQHLKEANDALDSASRLAEQLDLKEEQLEDLKKQVVAQHDMLEDAQKKLLNLVNNSEGRIDKVLMRNLFVGYFHTPKSKRNEAMRLLGCVLELKKEEISQL-LDGENRG-VTGWVTSWLGVNRVSGTQSFPSTPQRPNQRTIFNSSFSEMFVKFLEVESRPSLPPLKLPVYDM------HSVGAPSG------SSQPSNSIPGHSAGPSEGSVKKSDSNP 1644

HSP 2 Score: 40.4318 bits (93), Expect = 9.741e-34
Identity = 32/70 (45.71%), Postives = 46/70 (65.71%), Query Frame = 1 
Query:  343 ERAQLELLLHHQKQAECDSYIDQIXXXXXXXXXXXXXXXIFQDHLIRIEESYTQEATLAEDREQSLRKLA 552
            ER Q+ L L  QKQ E  + +++++  + KE +L ++ Q  + HLI +EESYT+EA  AEDRE  LRK A
Sbjct: 1264 ERDQVMLALK-QKQMENSALVNELQHTRDKEQRLNQDLQRLRHHLIEMEESYTKEALAAEDREAELRKRA 1332
[Close]
BLAST of Thyroid hormone receptor interactor 11 vs. TrEMBL
Match: W5N6P7 (Thyroid hormone receptor interactor 11 OS=Lepisosteus oculatus OX=7918 PE=4 SV=1)

HSP 1 Score: 135.191 bits (339), Expect = 2.315e-33
Identity = 83/246 (33.74%), Postives = 146/246 (59.35%), Query Frame = 2 
Query:  632 LSSEMNELRIERDAAKLQLGEAEVQLAENLRSLGNLQSVLEKFQQEQSLEMLYQKERFQQDIDRLIRERDSCAERNRSLQNEMDNQRDLVDAAQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKLNSFTESKVDKVLMKNLVIGYFHTPTHRRQEALKVIGSLLQFADSDYNQIGIDTANR-SRWF-NWLRPSVGDKASGTDDRAVPG------KSFSELFITFLENESSPI-PQVKLPT 1342
            L  ++N +  +RD A +QL  ++ Q+ +   SL NLQ VLE+FQQE+      + E+++++     R+ +   +R  ++Q  +D     +++A RLTDQ++ K++Q+ ELQ  ++ R+E+++  + ++  L + TE KVDKVLM+NL +G+FHTP ++R EAL+++GS+L     + +++ ++  +  + W  +WL          T  R  PG       SFSE+F+ FLE ES P  P ++LP 
Sbjct: 1636 LQEQLNTVARQRDEALMQLRTSQEQVNQYAVSLSNLQMVLEQFQQEEKAMYSAELEKYKKERAEWKRKAEKLEDRLAAMQINLDEANAALESASRLTDQLDLKEEQIEELQKQVALRQEMLEEAQNKLMNLLNSTEGKVDKVLMRNLFVGHFHTPKNKRHEALRLMGSVLGLKKDEMDKLLLEEPHGVTGWVSSWLGGRTAQSVPNTPQR--PGHSSQMNSSFSEMFVKFLEVESRPTAPPLRLPV 1879

HSP 2 Score: 38.1206 bits (87), Expect = 2.315e-33
Identity = 31/68 (45.59%), Postives = 45/68 (66.18%), Query Frame = 1 
Query:  343 ERAQLELLLHHQKQAECDSYIDQIXXXXXXXXXXXXXXXIFQDHLIRIEESYTQEATLAEDREQSLRK 546
            ER Q+ L L  QKQ E  +  ++++ +K KE +L +E +  + HLI IE+SYT+EA  AEDRE  LR+
Sbjct: 1540 ERDQVMLALK-QKQMETSALQNELQHMKDKEQRLKQELERLRTHLIEIEDSYTREAVAAEDREAELRR 1606
[Close]
BLAST of Thyroid hormone receptor interactor 11 vs. TrEMBL
Match: W5LPA0 (Thyroid hormone receptor interactor 11 OS=Astyanax mexicanus OX=7994 PE=4 SV=2)

HSP 1 Score: 136.346 bits (342), Expect = 2.354e-33
Identity = 89/253 (35.18%), Postives = 143/253 (56.52%), Query Frame = 2 
Query:  632 LSSEMNELRIERDAAKLQLGEAEVQLAENLRSLGNLQSVLEKFQQEQSLEMLYQKERFQQDIDRLIRERDSCAERNRSLQNEMDNQRDLVDAAQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKLNSFTESKVDKVLMKNLVIGYFHTPTHRRQEALKVIGSLLQFADSDYNQIGIDTANRSRWFNWLRPSVGDKASGTDDRAVPGK------------SFSELFITFLENESSP-IPQVKLPTNQI 1351
            L  ++N +  +RD A +QL  A+ Q+ +   SL NLQ VLE+FQQE+      + ER  ++ D   R+ ++  ++  +LQ  +D     +++A RLTDQ++ K++Q+ EL+  +  R+E++D  + ++  L + TE KVDKVLMKNL +GYFHTP ++R E L+++G++L     +  Q+  D   +     W+   +G    G   ++VP              SFSE+F+ FLE ESSP  P  KLP   I
Sbjct: 1609 LQEQLNVVVRQRDEALIQLRAAQEQVNQYAVSLSNLQMVLEQFQQEEKAMYSAELERHNKEKDDWRRKAETLEDKASALQLNLDEANAALESASRLTDQLDLKEEQIEELKKQVEVRQEMLDEAQKKLTNLLNSTEGKVDKVLMKNLFLGYFHTPRNKRAEVLRLMGNVLGLEPDEVEQMLNDEGKKG-VTGWVSGWLG---GGRAVQSVPNTPQRPTHTQNLNGSFSEMFVKFLEVESSPAAPAPKLPVYDI 1857

HSP 2 Score: 36.965 bits (84), Expect = 2.354e-33
Identity = 16/28 (57.14%), Postives = 22/28 (78.57%), Query Frame = 1 
Query:  463 FQDHLIRIEESYTQEATLAEDREQSLRK 546
             ++HL+ IE+SYT+EA  AEDRE  LR+
Sbjct: 1552 LRNHLLEIEDSYTREALAAEDRESDLRR 1579
[Close]
BLAST of Thyroid hormone receptor interactor 11 vs. TrEMBL
Match: G7YIG4 (Thyroid receptor-interacting protein 11 OS=Clonorchis sinensis OX=79923 GN=CLF_108742 PE=4 SV=1)

HSP 1 Score: 142.51 bits (358), Expect = 2.465e-33
Identity = 93/276 (33.70%), Postives = 153/276 (55.43%), Query Frame = 2 
Query:  593 TKLQRIIANIRSELSSEMNELRI-----ERDAAKLQLGEAEVQLAENLRSLGNLQSVLEKFQQEQSLEMLYQKERFQQDIDRL-IRERDSCAERNRSLQNEMDNQRDLVDAAQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKLNSFTESKVDKVLMKNLVIGYFHTPTHRRQEALKVIGSLLQFADSDYNQIGIDTANRSRWFNWLRPSVGDKASG-----TDDRAVPGKSFSELFITFLENESSPIPQVKLPTNQITAEARQHSSLSQ 1387
            T+LQ++      E SS+  E R+     ERD A+    E   +++    SLGNLQSVL+ FQQ Q   +  + E  + ++ R   RE  +CAE NR L  ++ ++  L   A  L  QI+H   QLA+L+  + +R+  ID  +  + ++   T+SK+DK+L++NL++ +F  P+ +R   L+VIGSLL F++ DY ++G ++    R   W+R +V     G     T     P K+F+EL ++FLE ES P   ++L  +  T +A + S+ +Q
Sbjct:  914 TRLQQL------EESSQTVEDRVQRYMAERDEARTDAAEYRKEISALRASLGNLQSVLDSFQQSQQSTIQCETEHIRMELQRARHREEAACAEVNR-LNGQLSDRIVLEQRAHHLDLQIQHHATQLAQLREQIEQRDSQIDALRTRLAQMAVDTDSKIDKLLIRNLLVSFFQLPSSQRSSGLRVIGSLLDFSNDDYAKVGSESGALPRLLGWVRSAVSSFPPGPPKDVTLSSTYPDKTFTELLLSFLEQESGPRAPLRLSMDHYTPDAVRPSASAQ 1182

HSP 2 Score: 31.187 bits (69), Expect = 2.465e-33
Identity = 16/27 (59.26%), Postives = 18/27 (66.67%), Query Frame = 1 
Query:  463 FQDHLIRIEESYTQEATLAEDREQSLR 543
             Q HL+ +EESYT EA  AE RE  LR
Sbjct:  880 LQAHLLEMEESYTTEALNAEAREVDLR 906
[Close]
BLAST of Thyroid hormone receptor interactor 11 vs. Ensembl Cavefish
Match: trip11 (thyroid hormone receptor interactor 11 [Source:ZFIN;Acc:ZDB-GENE-030131-9833])

HSP 1 Score: 136.346 bits (342), Expect = 1.538e-36
Identity = 89/253 (35.18%), Postives = 143/253 (56.52%), Query Frame = 2 
Query:  632 LSSEMNELRIERDAAKLQLGEAEVQLAENLRSLGNLQSVLEKFQQEQSLEMLYQKERFQQDIDRLIRERDSCAERNRSLQNEMDNQRDLVDAAQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKLNSFTESKVDKVLMKNLVIGYFHTPTHRRQEALKVIGSLLQFADSDYNQIGIDTANRSRWFNWLRPSVGDKASGTDDRAVPGK------------SFSELFITFLENESSP-IPQVKLPTNQI 1351
            L  ++N +  +RD A +QL  A+ Q+ +   SL NLQ VLE+FQQE+      + ER  ++ D   R+ ++  ++  +LQ  +D     +++A RLTDQ++ K++Q+ EL+  +  R+E++D  + ++  L + TE KVDKVLMKNL +GYFHTP ++R E L+++G++L     +  Q+  D   +     W+   +G    G   ++VP              SFSE+F+ FLE ESSP  P  KLP   I
Sbjct: 1609 LQEQLNVVVRQRDEALIQLRAAQEQVNQYAVSLSNLQMVLEQFQQEEKAMYSAELERHNKEKDDWRRKAETLEDKASALQLNLDEANAALESASRLTDQLDLKEEQIEELKKQVEVRQEMLDEAQKKLTNLLNSTEGKVDKVLMKNLFLGYFHTPRNKRAEVLRLMGNVLGLEPDEVEQMLNDEGKKG-VTGWVSGWLG---GGRAVQSVPNTPQRPTHTQNLNGSFSEMFVKFLEVESSPAAPAPKLPVYDI 1857

HSP 2 Score: 36.965 bits (84), Expect = 1.538e-36
Identity = 16/28 (57.14%), Postives = 22/28 (78.57%), Query Frame = 1 
Query:  463 FQDHLIRIEESYTQEATLAEDREQSLRK 546
             ++HL+ IE+SYT+EA  AEDRE  LR+
Sbjct: 1552 LRNHLLEIEDSYTREALAAEDRESDLRR 1579
[Close]
BLAST of Thyroid hormone receptor interactor 11 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007900.1 (pep scaffold:Pmarinus_7.0:GL476438:656513:684230:-1 gene:ENSPMAG00000007124.1 transcript:ENSPMAT00000007900.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 111.309 bits (277), Expect = 4.618e-26
Identity = 76/247 (30.77%), Postives = 144/247 (58.30%), Query Frame = 2 
Query:  614 ANIRSE-LSSEMNELRIERDAAKLQLGEAEVQLAENLRSLGNLQSVLEKFQQEQSLEMLYQKERFQQDIDRLIRERDSCAERNRSLQNEMDNQRDLVDAAQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKLNSFTESKVDKVLMKNLVIGYFHTPTHRRQEALKVIGSLLQFADSDYNQIGID-TANRSRWF-NWL-------RPSVGDKASGTDDRAVPGKSFSELFITFLENESSPIP 1324
            A++R++ L  ++  + ++RD A  Q  +A  Q  +   SL NLQ+VLE+FQQE+      + E+ +++    +++ +   ++ + LQ ++D   D +++A RLT+Q++ KD ++ ELQ  +  ++E+++  + ++  L + +E KVDKVL++N+++GYF TP ++R E LK++G +L     D +++  D     ++W  +WL        P+   K+   +       SFSE+F+ FLE ES P P
Sbjct: 1598 ASMRADMLQEQLRAVSLQRDTAVQQCNDARQQAQQYAASLSNLQTVLEQFQQEEKSMYATELEKHRREAQSNLQKANQMQQQVKQLQEQLDEANDALESASRLTEQLDLKDARIEELQRQVLLQQEMLEEVQTKMMNLLNSSEGKVDKVLLRNILVGYFSTPKNKRVEVLKLMGVVLGVKREDMDKLVSDEQVTVTKWVSSWLGGGSSHNHPAASHKSHNLE----MNSSFSEMFLKFLETESLPSP 1840

HSP 2 Score: 24.2534 bits (51), Expect = 4.618e-26
Identity = 10/23 (43.48%), Postives = 17/23 (73.91%), Query Frame = 1 
Query:  472 HLIRIEESYTQEATLAEDREQSL 540
            HL+++EE++T E    ++RE SL
Sbjct: 1551 HLVQVEEAHTLEDLAGQEREASL 1573
[Close]
BLAST of Thyroid hormone receptor interactor 11 vs. Ensembl Medaka
Match: trip11 (thyroid hormone receptor interactor 11 [Source:NCBI gene;Acc:101170802])

HSP 1 Score: 122.094 bits (305), Expect = 2.421e-28
Identity = 78/235 (33.19%), Postives = 135/235 (57.45%), Query Frame = 2 
Query:  662 ERDAAKLQLGEAEVQLAENLRSLGNLQSVLEKFQQEQSLEMLYQKERFQQDIDRLIRERDSCAERNRSLQNEMDNQRDLVDAAQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKLNSFTESKVDKVLMKNLVIGYFHTPTHRRQEALKVIGSLLQFADSDYNQIGIDTANR--SRWF-NWLRPSVGDKASGTDDRAVPGK----SFSELFITFLENESSP-IPQVKLPT 1342
            +RD    QL  ++ Q+ +   SL NLQ VLE+FQQE+      + E+ +++ +   R+     ++  +LQ  ++     +D+A RLTDQ++ K++Q+ EL+  +  R+E+++  + ++  L + TE K+DKVLM+NL +GYFHTP  +R + L+++GS+L  +  D +++  +   R  + W  +WL          T  R   G+    SFSE+F+ FLE ES+P  P  +LP 
Sbjct: 1610 QRDDTLAQLRTSQEQVNQYAVSLSNLQMVLEQFQQEEKSMYTAELEKHKREKEEWRRKALLLEDQASALQVNLEEAHAALDSASRLTDQLDLKEEQIEELKKQIHVRQEMLEEAQNKLMNLLNSTEGKIDKVLMRNLFLGYFHTPKAKRADVLRLMGSVLGLSREDVDKMLEEDVQRGVTGWMSSWLGGRGAQSVPNTPQRPGGGQGLNSSFSEMFVKFLEMESTPSAPAPRLPV 1844
[Close]
BLAST of Thyroid hormone receptor interactor 11 vs. Ensembl Medaka
Match: trip11 (thyroid hormone receptor interactor 11 [Source:NCBI gene;Acc:101170802])

HSP 1 Score: 122.094 bits (305), Expect = 2.631e-28
Identity = 78/235 (33.19%), Postives = 135/235 (57.45%), Query Frame = 2 
Query:  662 ERDAAKLQLGEAEVQLAENLRSLGNLQSVLEKFQQEQSLEMLYQKERFQQDIDRLIRERDSCAERNRSLQNEMDNQRDLVDAAQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKLNSFTESKVDKVLMKNLVIGYFHTPTHRRQEALKVIGSLLQFADSDYNQIGIDTANR--SRWF-NWLRPSVGDKASGTDDRAVPGK----SFSELFITFLENESSP-IPQVKLPT 1342
            +RD    QL  ++ Q+ +   SL NLQ VLE+FQQE+      + E+ +++ +   R+     ++  +LQ  ++     +D+A RLTDQ++ K++Q+ EL+  +  R+E+++  + ++  L + TE K+DKVLM+NL +GYFHTP  +R + L+++GS+L  +  D +++  +   R  + W  +WL          T  R   G+    SFSE+F+ FLE ES+P  P  +LP 
Sbjct: 1633 QRDDTLAQLRTSQEQVNQYAVSLSNLQMVLEQFQQEEKSMYTAELEKHKREKEEWRRKALLLEDQASALQVNLEEAHAALDSASRLTDQLDLKEEQIEELKKQIHVRQEMLEEAQNKLMNLLNSTEGKIDKVLMRNLFLGYFHTPKAKRADVLRLMGSVLGLSREDVDKMLEEDVQRGVTGWMSSWLGGRGAQSVPNTPQRPGGGQGLNSSFSEMFVKFLEMESTPSAPAPRLPV 1867
[Close]
BLAST of Thyroid hormone receptor interactor 11 vs. Ensembl Medaka
Match: trip11 (thyroid hormone receptor interactor 11 [Source:NCBI gene;Acc:101170802])

HSP 1 Score: 115.546 bits (288), Expect = 3.227e-26
Identity = 69/212 (32.55%), Postives = 123/212 (58.02%), Query Frame = 2 
Query:  731 GNLQSVLEKFQQEQSLEMLYQKERFQQDIDRLIRERDSCAERNRSLQNEMDNQRDLVDAAQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKLNSFTESKVDKVLMKNLVIGYFHTPTHRRQEALKVIGSLLQFADSDYNQIGIDTANR--SRWF-NWLRPSVGDKASGTDDRAVPGK----SFSELFITFLENESSP-IPQVKLPT 1342
             ++Q VLE+FQQE+      + E+ +++ +   R+     ++  +LQ  ++     +D+A RLTDQ++ K++Q+ EL+  +  R+E+++  + ++  L + TE K+DKVLM+NL +GYFHTP  +R + L+++GS+L  +  D +++  +   R  + W  +WL          T  R   G+    SFSE+F+ FLE ES+P  P  +LP 
Sbjct: 1616 ASMQMVLEQFQQEEKSMYTAELEKHKREKEEWRRKALLLEDQASALQVNLEEAHAALDSASRLTDQLDLKEEQIEELKKQIHVRQEMLEEAQNKLMNLLNSTEGKIDKVLMRNLFLGYFHTPKAKRADVLRLMGSVLGLSREDVDKMLEEDVQRGVTGWMSSWLGGRGAQSVPNTPQRPGGGQGLNSSFSEMFVKFLEMESTPSAPAPRLPV 1827
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BLAST of Thyroid hormone receptor interactor 11 vs. Planmine SMEST
Match: SMESG000037100.1 (SMESG000037100.1)

HSP 1 Score: 696.427 bits (1796), Expect = 0.000e+0
Identity = 358/375 (95.47%), Postives = 359/375 (95.73%), Query Frame = 2 
Query:  548 LRDSEDKLQMATDDITKLQRIIANIRSELSSEMNELRIERDAAKLQLGEAEVQLAENLRSLGNLQSVLEKFQQEQSLEMLYQKERFQQDIDRLIRERDSCAERNRSLQNEMDNQRDLVDAAQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKLNSFTESKVDKVLMKNLVIGYFHTPTHRRQEALKVIGSLLQFADSDYNQIGIDTANRSRWFNWLRPSVGDKASGTDDRAVPGKSFSELFITFLENESSPIPQVKLPTNQITAEARQHSSLSQSDEYPYTHSTSLTSIIDHHKFFPASPVVTKRNGSPSIDNQQPTEQNQQSAKPSTLLFXXXXXXXXXXXXQKEFKXXXXXXXXXXXXXVLLSLLDQ 1672
            LRDSEDKLQMATDDI+KLQRIIANIRSELSSEMNELRIERDAAKLQLGEAEVQLAENLRSLGNLQSVLEKFQQEQSLEMLYQKERFQQDIDRLIRERDSCAERNRSLQNEMDNQRDLVDAAQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKLNSFTESKVDKVLMKNLVIGYFHTPTHRRQEALKVIGSLLQFADSDYNQIGIDTANRSRWFNWLRPS GDKASGTDDRAVPGKSFSELFITFLENESSPIPQVKLPTNQITAEARQHSSLSQSDEYPYTHSTSLTSIIDHHKFFPASPVVTKRNGSPSIDNQQPTEQNQQSAKPS              SNQKEFKS SNHRRSESNRNVLLSLLDQ
Sbjct: 1334 LRDSEDKLQMATDDISKLQRIIANIRSELSSEMNELRIERDAAKLQLGEAEVQLAENLRSLGNLQSVLEKFQQEQSLEMLYQKERFQQDIDRLIRERDSCAERNRSLQNEMDNQRDLVDAAQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKLNSFTESKVDKVLMKNLVIGYFHTPTHRRQEALKVIGSLLQFADSDYNQIGIDTANRSRWFNWLRPSAGDKASGTDDRAVPGKSFSELFITFLENESSPIPQVKLPTNQITAEARQHSSLSQSDEYPYTHSTSLTSIIDHHKFFPASPVVTKRNGSPSIDNQQPTEQNQQSAKPSN-------------SNQKEFKSLSNHRRSESNRNVLLSLLDQ 1695

HSP 2 Score: 331.257 bits (848), Expect = 0.000e+0
Identity = 180/182 (98.90%), Postives = 180/182 (98.90%), Query Frame = 1 
Query:    1 QHLVTASECHLCKQSRYQLNSCQQENRMKAAEMRNLQKNSEQIAFELEQARLQIAELTSSCDRAQKQLEFCQNELANQYKIHIVPSNRSDESTKSIWNTEYQKSEINKSDEEMDERAQLELLLHHQKQAECDSYIDQIXXXXXXXXXXXXXXXIFQDHLIRIEESYTQEATLAEDREQSLRK 546
            QHLVTASECHLCKQSR QLNSCQQENRMKAAEMRNLQKNSEQIAFELEQARLQIAELTSSCDRAQKQLEFCQNELANQYKIHIVPSNRSDESTKSIWNTEYQKSEINKSD EMDERAQLELLLHHQKQAECDSYIDQIEQLKAKEAKLLKEKQIFQDHLIRIEESYTQEATLAEDREQSLRK
Sbjct: 1151 QHLVTASECHLCKQSRDQLNSCQQENRMKAAEMRNLQKNSEQIAFELEQARLQIAELTSSCDRAQKQLEFCQNELANQYKIHIVPSNRSDESTKSIWNTEYQKSEINKSDGEMDERAQLELLLHHQKQAECDSYIDQIEQLKAKEAKLLKEKQIFQDHLIRIEESYTQEATLAEDREQSLRK 1332
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BLAST of Thyroid hormone receptor interactor 11 vs. Planmine SMEST
Match: SMESG000037100.1 (SMESG000037100.1)

HSP 1 Score: 696.427 bits (1796), Expect = 0.000e+0
Identity = 358/375 (95.47%), Postives = 359/375 (95.73%), Query Frame = 2 
Query:  548 LRDSEDKLQMATDDITKLQRIIANIRSELSSEMNELRIERDAAKLQLGEAEVQLAENLRSLGNLQSVLEKFQQEQSLEMLYQKERFQQDIDRLIRERDSCAERNRSLQNEMDNQRDLVDAAQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKLNSFTESKVDKVLMKNLVIGYFHTPTHRRQEALKVIGSLLQFADSDYNQIGIDTANRSRWFNWLRPSVGDKASGTDDRAVPGKSFSELFITFLENESSPIPQVKLPTNQITAEARQHSSLSQSDEYPYTHSTSLTSIIDHHKFFPASPVVTKRNGSPSIDNQQPTEQNQQSAKPSTLLFXXXXXXXXXXXXQKEFKXXXXXXXXXXXXXVLLSLLDQ 1672
            LRDSEDKLQMATDDI+KLQRIIANIRSELSSEMNELRIERDAAKLQLGEAEVQLAENLRSLGNLQSVLEKFQQEQSLEMLYQKERFQQDIDRLIRERDSCAERNRSLQNEMDNQRDLVDAAQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKLNSFTESKVDKVLMKNLVIGYFHTPTHRRQEALKVIGSLLQFADSDYNQIGIDTANRSRWFNWLRPS GDKASGTDDRAVPGKSFSELFITFLENESSPIPQVKLPTNQITAEARQHSSLSQSDEYPYTHSTSLTSIIDHHKFFPASPVVTKRNGSPSIDNQQPTEQNQQSAKPS              SNQKEFKS SNHRRSESNRNVLLSLLDQ
Sbjct: 1335 LRDSEDKLQMATDDISKLQRIIANIRSELSSEMNELRIERDAAKLQLGEAEVQLAENLRSLGNLQSVLEKFQQEQSLEMLYQKERFQQDIDRLIRERDSCAERNRSLQNEMDNQRDLVDAAQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKLNSFTESKVDKVLMKNLVIGYFHTPTHRRQEALKVIGSLLQFADSDYNQIGIDTANRSRWFNWLRPSAGDKASGTDDRAVPGKSFSELFITFLENESSPIPQVKLPTNQITAEARQHSSLSQSDEYPYTHSTSLTSIIDHHKFFPASPVVTKRNGSPSIDNQQPTEQNQQSAKPSN-------------SNQKEFKSLSNHRRSESNRNVLLSLLDQ 1696

HSP 2 Score: 331.257 bits (848), Expect = 0.000e+0
Identity = 180/182 (98.90%), Postives = 180/182 (98.90%), Query Frame = 1 
Query:    1 QHLVTASECHLCKQSRYQLNSCQQENRMKAAEMRNLQKNSEQIAFELEQARLQIAELTSSCDRAQKQLEFCQNELANQYKIHIVPSNRSDESTKSIWNTEYQKSEINKSDEEMDERAQLELLLHHQKQAECDSYIDQIXXXXXXXXXXXXXXXIFQDHLIRIEESYTQEATLAEDREQSLRK 546
            QHLVTASECHLCKQSR QLNSCQQENRMKAAEMRNLQKNSEQIAFELEQARLQIAELTSSCDRAQKQLEFCQNELANQYKIHIVPSNRSDESTKSIWNTEYQKSEINKSD EMDERAQLELLLHHQKQAECDSYIDQIEQLKAKEAKLLKEKQIFQDHLIRIEESYTQEATLAEDREQSLRK
Sbjct: 1152 QHLVTASECHLCKQSRDQLNSCQQENRMKAAEMRNLQKNSEQIAFELEQARLQIAELTSSCDRAQKQLEFCQNELANQYKIHIVPSNRSDESTKSIWNTEYQKSEINKSDGEMDERAQLELLLHHQKQAECDSYIDQIEQLKAKEAKLLKEKQIFQDHLIRIEESYTQEATLAEDREQSLRK 1333
[Close]
BLAST of Thyroid hormone receptor interactor 11 vs. Planmine SMEST
Match: SMESG000037100.1 (SMESG000037100.1)

HSP 1 Score: 695.656 bits (1794), Expect = 0.000e+0
Identity = 358/375 (95.47%), Postives = 359/375 (95.73%), Query Frame = 2 
Query:  548 LRDSEDKLQMATDDITKLQRIIANIRSELSSEMNELRIERDAAKLQLGEAEVQLAENLRSLGNLQSVLEKFQQEQSLEMLYQKERFQQDIDRLIRERDSCAERNRSLQNEMDNQRDLVDAAQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKLNSFTESKVDKVLMKNLVIGYFHTPTHRRQEALKVIGSLLQFADSDYNQIGIDTANRSRWFNWLRPSVGDKASGTDDRAVPGKSFSELFITFLENESSPIPQVKLPTNQITAEARQHSSLSQSDEYPYTHSTSLTSIIDHHKFFPASPVVTKRNGSPSIDNQQPTEQNQQSAKPSTLLFXXXXXXXXXXXXQKEFKXXXXXXXXXXXXXVLLSLLDQ 1672
            LRDSEDKLQMATDDI+KLQRIIANIRSELSSEMNELRIERDAAKLQLGEAEVQLAENLRSLGNLQSVLEKFQQEQSLEMLYQKERFQQDIDRLIRERDSCAERNRSLQNEMDNQRDLVDAAQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKLNSFTESKVDKVLMKNLVIGYFHTPTHRRQEALKVIGSLLQFADSDYNQIGIDTANRSRWFNWLRPS GDKASGTDDRAVPGKSFSELFITFLENESSPIPQVKLPTNQITAEARQHSSLSQSDEYPYTHSTSLTSIIDHHKFFPASPVVTKRNGSPSIDNQQPTEQNQQSAKPS              SNQKEFKS SNHRRSESNRNVLLSLLDQ
Sbjct: 1340 LRDSEDKLQMATDDISKLQRIIANIRSELSSEMNELRIERDAAKLQLGEAEVQLAENLRSLGNLQSVLEKFQQEQSLEMLYQKERFQQDIDRLIRERDSCAERNRSLQNEMDNQRDLVDAAQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKLNSFTESKVDKVLMKNLVIGYFHTPTHRRQEALKVIGSLLQFADSDYNQIGIDTANRSRWFNWLRPSAGDKASGTDDRAVPGKSFSELFITFLENESSPIPQVKLPTNQITAEARQHSSLSQSDEYPYTHSTSLTSIIDHHKFFPASPVVTKRNGSPSIDNQQPTEQNQQSAKPSN-------------SNQKEFKSLSNHRRSESNRNVLLSLLDQ 1701

HSP 2 Score: 331.257 bits (848), Expect = 0.000e+0
Identity = 180/182 (98.90%), Postives = 180/182 (98.90%), Query Frame = 1 
Query:    1 QHLVTASECHLCKQSRYQLNSCQQENRMKAAEMRNLQKNSEQIAFELEQARLQIAELTSSCDRAQKQLEFCQNELANQYKIHIVPSNRSDESTKSIWNTEYQKSEINKSDEEMDERAQLELLLHHQKQAECDSYIDQIXXXXXXXXXXXXXXXIFQDHLIRIEESYTQEATLAEDREQSLRK 546
            QHLVTASECHLCKQSR QLNSCQQENRMKAAEMRNLQKNSEQIAFELEQARLQIAELTSSCDRAQKQLEFCQNELANQYKIHIVPSNRSDESTKSIWNTEYQKSEINKSD EMDERAQLELLLHHQKQAECDSYIDQIEQLKAKEAKLLKEKQIFQDHLIRIEESYTQEATLAEDREQSLRK
Sbjct: 1157 QHLVTASECHLCKQSRDQLNSCQQENRMKAAEMRNLQKNSEQIAFELEQARLQIAELTSSCDRAQKQLEFCQNELANQYKIHIVPSNRSDESTKSIWNTEYQKSEINKSDGEMDERAQLELLLHHQKQAECDSYIDQIEQLKAKEAKLLKEKQIFQDHLIRIEESYTQEATLAEDREQSLRK 1338
The following BLAST results are available for this feature:
BLAST of Thyroid hormone receptor interactor 11 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 3
Match NameE-valueIdentityDescription
TRIP114.672e-3136.07thyroid hormone receptor interactor 11 [Source:HGN... [more]
TRIP115.652e-3136.07thyroid hormone receptor interactor 11 [Source:HGN... [more]
TRIP115.724e-636.52thyroid hormone receptor interactor 11 [Source:HGN... [more]
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BLAST of Thyroid hormone receptor interactor 11 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Thyroid hormone receptor interactor 11 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Gmap5.511e-928.27gene:FBgn0027287 transcript:FBtr0474150[more]
Gmap5.603e-928.27gene:FBgn0027287 transcript:FBtr0074042[more]
Gmap6.442e-928.27gene:FBgn0027287 transcript:FBtr0074043[more]
Gmap6.442e-928.27gene:FBgn0027287 transcript:FBtr0343525[more]
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BLAST of Thyroid hormone receptor interactor 11 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
trip112.738e-3034.26thyroid hormone receptor interactor 11 [Source:ZFI... [more]
trip111.340e-2934.11thyroid hormone receptor interactor 11 [Source:ZFI... [more]
trip111.485e-2934.11thyroid hormone receptor interactor 11 [Source:ZFI... [more]
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BLAST of Thyroid hormone receptor interactor 11 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
smc28.912e-2931.94structural maintenance of chromosomes 2 [Source:Xe... [more]
smc21.165e-2831.94structural maintenance of chromosomes 2 [Source:Xe... [more]
smc21.240e-2833.19structural maintenance of chromosomes 2 [Source:Xe... [more]
smc21.300e-2833.19structural maintenance of chromosomes 2 [Source:Xe... [more]
smc21.487e-2833.19structural maintenance of chromosomes 2 [Source:Xe... [more]
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BLAST of Thyroid hormone receptor interactor 11 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Trip113.450e-3236.18thyroid hormone receptor interactor 11 [Source:MGI... [more]
Trip114.234e-3236.18thyroid hormone receptor interactor 11 [Source:MGI... [more]
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BLAST of Thyroid hormone receptor interactor 11 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 1
Match NameE-valueIdentityDescription
sp|Q15643|TRIPB_HUMAN2.244e-3036.07Thyroid receptor-interacting protein 11 OS=Homo sa... [more]
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BLAST of Thyroid hormone receptor interactor 11 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A3R7FXB08.203e-3434.06Thyroid receptor-interacting protein 11 (Fragment)... [more]
A0A401NHT39.741e-3430.45GRIP domain-containing protein (Fragment) OS=Scyli... [more]
W5N6P72.315e-3333.74Thyroid hormone receptor interactor 11 OS=Lepisost... [more]
W5LPA02.354e-3335.18Thyroid hormone receptor interactor 11 OS=Astyanax... [more]
G7YIG42.465e-3333.70Thyroid receptor-interacting protein 11 OS=Clonorc... [more]
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BLAST of Thyroid hormone receptor interactor 11 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
trip111.538e-3635.18thyroid hormone receptor interactor 11 [Source:ZFI... [more]
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BLAST of Thyroid hormone receptor interactor 11 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSPMAT00000007900.14.618e-2630.77pep scaffold:Pmarinus_7.0:GL476438:656513:684230:-... [more]
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BLAST of Thyroid hormone receptor interactor 11 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Thyroid hormone receptor interactor 11 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Thyroid hormone receptor interactor 11 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
trip112.421e-2833.19thyroid hormone receptor interactor 11 [Source:NCB... [more]
trip112.631e-2833.19thyroid hormone receptor interactor 11 [Source:NCB... [more]
trip113.227e-2632.55thyroid hormone receptor interactor 11 [Source:NCB... [more]
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BLAST of Thyroid hormone receptor interactor 11 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000037100.10.000e+095.47SMESG000037100.1[more]
SMESG000037100.10.000e+095.47SMESG000037100.1[more]
SMESG000037100.10.000e+095.47SMESG000037100.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30021093 ID=SMED30021093|Name=Thyroid hormone receptor interactor 11|organism=Schmidtea mediterranea sexual|type=transcript|length=1809bp
CAGCACCTAGTAACGGCATCAGAATGCCATCTATGCAAGCAATCGAGATA
TCAGTTGAACAGTTGCCAGCAGGAAAACAGAATGAAAGCTGCGGAAATGA
GAAATTTGCAGAAGAATTCGGAACAGATTGCATTCGAGCTAGAACAAGCC
CGACTACAAATTGCTGAATTGACGAGCAGTTGTGATCGAGCTCAGAAGCA
ATTGGAGTTCTGTCAGAACGAGCTGGCCAATCAATACAAGATTCACATCG
TCCCCAGCAACCGCTCGGACGAGTCGACAAAGAGCATATGGAACACAGAA
TATCAAAAGAGTGAAATCAATAAGAGTGATGAAGAGATGGACGAGAGAGC
TCAACTGGAACTGCTGCTACACCACCAGAAGCAGGCCGAATGTGACAGTT
ATATTGATCAGATTGAGCAGCTCAAGGCCAAGGAAGCCAAACTGTTGAAG
GAAAAACAGATTTTCCAGGATCATCTGATACGAATTGAAGAATCGTACAC
CCAAGAGGCAACACTTGCAGAAGACAGAGAACAGAGCTTGCGTAAGCTTG
CGTGATAGTGAAGACAAATTACAGATGGCCACTGATGACATCACCAAATT
ACAGAGAATCATTGCCAATATCCGAAGCGAGTTGAGTAGTGAAATGAATG
AGTTGCGAATCGAGCGAGATGCAGCGAAACTGCAACTGGGAGAGGCTGAA
GTGCAACTGGCAGAAAATTTGAGAAGCCTAGGAAATCTGCAATCGGTGCT
GGAAAAGTTCCAGCAAGAGCAATCATTGGAAATGCTCTATCAGAAGGAAC
GCTTTCAGCAGGACATCGACAGGCTCATTAGGGAGCGCGACAGTTGCGCT
GAGAGGAACAGGAGTTTGCAGAACGAAATGGACAATCAAAGAGATCTAGT
TGATGCTGCACAAAGGTTAACTGATCAAATCGAGCACAAGGATGACCAAT
TGGCTGAGCTGCAAGCTTTATTGTCCAGGCGGGAGGAACTTATCGACCAC
TACAAAATGGAAATCCGCAAGTTGAACAGTTTTACTGAATCCAAAGTTGA
CAAAGTGCTCATGAAGAACCTTGTCATTGGATATTTCCATACGCCGACTC
ACCGCAGGCAGGAAGCTTTGAAAGTTATTGGAAGTTTATTGCAATTTGCA
GATTCCGATTACAATCAGATTGGAATCGACACCGCAAATAGATCTCGGTG
GTTCAACTGGCTGCGTCCTAGTGTAGGGGACAAGGCTTCTGGTACCGATG
ACCGAGCAGTTCCTGGAAAGTCGTTTTCAGAATTATTCATTACATTTCTG
GAAAATGAATCCAGTCCGATTCCCCAGGTTAAATTGCCGACCAATCAGAT
TACCGCTGAAGCCAGACAGCATTCGTCTCTATCCCAATCAGATGAATATC
CGTATACCCATTCTACCTCTTTGACGTCCATCATTGATCACCACAAATTT
TTCCCCGCTTCTCCTGTCGTCACCAAGCGTAACGGATCTCCAAGCATTGA
CAACCAGCAGCCAACAGAGCAGAACCAGCAGTCAGCCAAACCTTCCACTT
TGCTCTTTATTCCAAATATTAATGACAATAATTCAGATTCCAATCAAAAA
GAATTCAAATCATCATCAAATCATCGGAGGTCAGAAAGCAATCGGAACGT
CCTTCTAAGCCTGTTGGACCAGTAATAATGGTCTGTTTGTGTGCCTTGGA
ATTAATAATGATTATTAACAACATTCTGTGATTTATTTGTTTACTGCCGG
GTGTTTTGATCCGTCATTGATTATTGGTTTCTTGTCTTATAAATAGATCA
TTGTTTTTG
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protein sequence of SMED30021093-orf-1

>SMED30021093-orf-1 ID=SMED30021093-orf-1|Name=SMED30021093-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=185bp
QHLVTASECHLCKQSRYQLNSCQQENRMKAAEMRNLQKNSEQIAFELEQA
RLQIAELTSSCDRAQKQLEFCQNELANQYKIHIVPSNRSDESTKSIWNTE
YQKSEINKSDEEMDERAQLELLLHHQKQAECDSYIDQIEQLKAKEAKLLK
EKQIFQDHLIRIEESYTQEATLAEDREQSLRKLA*
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protein sequence of SMED30021093-orf-2

>SMED30021093-orf-2 ID=SMED30021093-orf-2|Name=SMED30021093-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=367bp
MATDDITKLQRIIANIRSELSSEMNELRIERDAAKLQLGEAEVQLAENLR
SLGNLQSVLEKFQQEQSLEMLYQKERFQQDIDRLIRERDSCAERNRSLQN
EMDNQRDLVDAAQRLTDQIEHKDDQLAELQALLSRREELIDHYKMEIRKL
NSFTESKVDKVLMKNLVIGYFHTPTHRRQEALKVIGSLLQFADSDYNQIG
IDTANRSRWFNWLRPSVGDKASGTDDRAVPGKSFSELFITFLENESSPIP
QVKLPTNQITAEARQHSSLSQSDEYPYTHSTSLTSIIDHHKFFPASPVVT
KRNGSPSIDNQQPTEQNQQSAKPSTLLFIPNINDNNSDSNQKEFKSSSNH
RRSESNRNVLLSLLDQ*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
PLANA:0000099neuron
PLANA:0002032epidermal cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR000237GRIP_dom
Vocabulary: biological process
TermDefinition
GO:0000042protein targeting to Golgi
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
Vocabulary: cellular component
TermDefinition
GO:0005622intracellular
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 124..158
NoneNo IPR availableCOILSCoilCoilcoord: 19..74