V(D)J recombination-activating protein 1

Overview
NameV(D)J recombination-activating protein 1
Smed IDSMED30021059
Length (bp)1593
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of V(D)J recombination-activating protein 1 (SMED30021059) t-SNE clustered cells

Violin plots show distribution of expression levels for V(D)J recombination-activating protein 1 (SMED30021059) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of V(D)J recombination-activating protein 1 (SMED30021059) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for V(D)J recombination-activating protein 1 (SMED30021059) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30021059

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30021059h1SMcG0014844 dd_Smed_v4_11354_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30021059h1SMcG0014844 dd_Smed_v4_11354_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30021059h1SMcG0014844 dd_Smed_v4_11354_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pharynxSMED30021059h1SMcG0014844 SMED30021059smed_20140614PMID:26457503
Tu et al., 2015		whole organism asexual adult colorimetric in situ hybridization evidence
gutSMED30021059h1SMcG0014844 SMED30021059smed_20140614PMID:26457503
Tu et al., 2015		whole organism asexual adult colorimetric in situ hybridization evidence
parenchymaSMED30021059h1SMcG0014844 SMED30021059smed_20140614PMID:26457503
Tu et al., 2015		whole organism asexual adult colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Human
Match: TRAF6 (TNF receptor associated factor 6 [Source:HGNC Symbol;Acc:HGNC:12036])

HSP 1 Score: 63.1586 bits (152), Expect = 7.284e-10
Identity = 35/117 (29.91%), Postives = 59/117 (50.43%), Query Frame = 3 
Query:  174 MEQYQFDIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCDKLPFWCP 524
            ++ Y  + DP L    +C IC   L +A Q PCG  +CK CI K + ++   CP +      +++ + + +  DN A  ++  L+V CP EGC  +  L  + +H  +C+     CP
Sbjct:   53 IQGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVD------NEILLENQLFPDNFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALMDCP 163
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Human
Match: TRAF6 (TNF receptor associated factor 6 [Source:HGNC Symbol;Acc:HGNC:12036])

HSP 1 Score: 63.1586 bits (152), Expect = 7.284e-10
Identity = 35/117 (29.91%), Postives = 59/117 (50.43%), Query Frame = 3 
Query:  174 MEQYQFDIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCDKLPFWCP 524
            ++ Y  + DP L    +C IC   L +A Q PCG  +CK CI K + ++   CP +      +++ + + +  DN A  ++  L+V CP EGC  +  L  + +H  +C+     CP
Sbjct:   53 IQGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVD------NEILLENQLFPDNFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALMDCP 163
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Human
Match: TRAF2 (TNF receptor associated factor 2 [Source:HGNC Symbol;Acc:HGNC:12032])

HSP 1 Score: 50.447 bits (119), Expect = 5.651e-6
Identity = 32/104 (30.77%), Postives = 47/104 (45.19%), Query Frame = 3 
Query:  225 CIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGN-HKDCKSSKLDIF--SNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEM-SNHLQNCDKLPFWCP 524
            C  C N+L    Q  CG  YC  C+   L++  + C    H+      + I   S+   DN+A  +V  L  +CP +GC ++ TL E  S H   C  +   CP
Sbjct:   34 CSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYESCHEGRCPLMLTECP 137
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Human
Match: TRAF2 (TNF receptor associated factor 2 [Source:HGNC Symbol;Acc:HGNC:12032])

HSP 1 Score: 46.9802 bits (110), Expect = 7.744e-6
Identity = 27/87 (31.03%), Postives = 41/87 (47.13%), Query Frame = 3 
Query:  225 CIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGN-HKDCKSSKLDIF--SNIVKDNSANNKVSKLIVICPGEGCNFQSTLIE 476
            C  C N+L    Q  CG  YC  C+   L++  + C    H+      + I   S+   DN+A  +V  L  +CP +GC ++ TL E
Sbjct:   34 CSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKE 120
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Fly
Match: Traf6 (gene:FBgn0265464 transcript:FBtr0071188)

HSP 1 Score: 61.2326 bits (147), Expect = 1.180e-9
Identity = 40/158 (25.32%), Postives = 75/158 (47.47%), Query Frame = 3 
Query:  222 KCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGE--GCNFQSTLIEMSNHLQNCDKLPFW---------CPYAEIGCT-TNTMLTDELVDHLQTEIVAHNNLLVKWITSAPDNSHQP 659
            +C IC + LN+     CG  +C+ C+  ++  + + CP ++K     +L    +I  DN    ++ +L   CP    GC+  ++ IE+  HL +C   P+          CP+A+I C       T++L +HL+ ++  H  L+++        + QP
Sbjct:  103 ECAICIDWLNEPVLTSCGHRFCRSCLTAWMQKNNQCCPMDNK-----RLSAEHDIFPDNYTRREIEQLKRDCPNSSLGCSVVASPIELHRHLPSC---PYRRQQEPQEEKCPFAKIKCDFVGRPETNQLEEHLKADMPHHMQLMLQAFQQTAIATWQP 252
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Zebrafish
Match: traf6 (TNF receptor-associated factor 6 [Source:NCBI gene;Acc:554561])

HSP 1 Score: 55.4546 bits (132), Expect = 1.068e-7
Identity = 33/114 (28.95%), Postives = 52/114 (45.61%), Query Frame = 3 
Query:  183 YQFDIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCDKLPFWCP 524
            Y  + DP L    +C IC   L  A Q PCG  +C  CI K + ++ + CP +      +++ +   +  DN A  ++  L V C   GC+ +  L ++  HL  C      CP
Sbjct:   57 YDVEFDPPLESKYECPICLMGLRSAVQTPCGHRFCDSCIRKSIRDTGQKCPVD------NEVLLEEQLFPDNFAKREILSLTVKCSNFGCSEKMELRQLEKHLSQCRFATAPCP 164
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Zebrafish
Match: traf6 (TNF receptor-associated factor 6 [Source:NCBI gene;Acc:554561])

HSP 1 Score: 55.4546 bits (132), Expect = 1.068e-7
Identity = 33/114 (28.95%), Postives = 52/114 (45.61%), Query Frame = 3 
Query:  183 YQFDIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCDKLPFWCP 524
            Y  + DP L    +C IC   L  A Q PCG  +C  CI K + ++ + CP +      +++ +   +  DN A  ++  L V C   GC+ +  L ++  HL  C      CP
Sbjct:   57 YDVEFDPPLESKYECPICLMGLRSAVQTPCGHRFCDSCIRKSIRDTGQKCPVD------NEVLLEEQLFPDNFAKREILSLTVKCSNFGCSEKMELRQLEKHLSQCRFATAPCP 164
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Zebrafish
Match: traf6 (TNF receptor-associated factor 6 [Source:NCBI gene;Acc:554561])

HSP 1 Score: 55.4546 bits (132), Expect = 1.068e-7
Identity = 33/114 (28.95%), Postives = 52/114 (45.61%), Query Frame = 3 
Query:  183 YQFDIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCDKLPFWCP 524
            Y  + DP L    +C IC   L  A Q PCG  +C  CI K + ++ + CP +      +++ +   +  DN A  ++  L V C   GC+ +  L ++  HL  C      CP
Sbjct:   57 YDVEFDPPLESKYECPICLMGLRSAVQTPCGHRFCDSCIRKSIRDTGQKCPVD------NEVLLEEQLFPDNFAKREILSLTVKCSNFGCSEKMELRQLEKHLSQCRFATAPCP 164
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Zebrafish
Match: rnf41 (ring finger protein 41 [Source:NCBI gene;Acc:406837])

HSP 1 Score: 49.2914 bits (116), Expect = 6.421e-6
Identity = 42/167 (25.15%), Postives = 74/167 (44.31%), Query Frame = 3 
Query:  180 QYQFDIDPQLSIYVKCIICNNLLNDACQGP-CGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVIC--PGEGCNFQSTLIEMSNHLQNCDKLPFWCPYAEIGCTTNTMLTDEL-----VDHLQTEIVAHNNLLVKWITSAPDNSHQ 656
            ++Q ++D  L     C IC+ +L +  Q P C   +C  CI ++ A   + CP +      + L     I++     N +SKL + C   G GC     L ++ +HL++C+  P      E GC    M  DE+     + HL++ +      +     +A ++ HQ
Sbjct:    7 RFQGEVDEDLL----CPICSGVLEEPVQAPHCEHAFCNACITQWFAQQ-QICPVDRTVVTLAHLRPVPRIMR-----NMLSKLQISCDNAGFGCTATLRLDQLQSHLKDCEHNPKRPVTCEEGCGLE-MPKDEMPNHNCIKHLRSVVQQQQTKIADLEKTAAEHKHQ 162
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Zebrafish
Match: rnf41 (ring finger protein 41 [Source:NCBI gene;Acc:406837])

HSP 1 Score: 49.2914 bits (116), Expect = 6.421e-6
Identity = 42/167 (25.15%), Postives = 74/167 (44.31%), Query Frame = 3 
Query:  180 QYQFDIDPQLSIYVKCIICNNLLNDACQGP-CGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVIC--PGEGCNFQSTLIEMSNHLQNCDKLPFWCPYAEIGCTTNTMLTDEL-----VDHLQTEIVAHNNLLVKWITSAPDNSHQ 656
            ++Q ++D  L     C IC+ +L +  Q P C   +C  CI ++ A   + CP +      + L     I++     N +SKL + C   G GC     L ++ +HL++C+  P      E GC    M  DE+     + HL++ +      +     +A ++ HQ
Sbjct:    7 RFQGEVDEDLL----CPICSGVLEEPVQAPHCEHAFCNACITQWFAQQ-QICPVDRTVVTLAHLRPVPRIMR-----NMLSKLQISCDNAGFGCTATLRLDQLQSHLKDCEHNPKRPVTCEEGCGLE-MPKDEMPNHNCIKHLRSVVQQQQTKIADLEKTAAEHKHQ 162
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Xenopus
Match: egf (epidermal growth factor [Source:Xenbase;Acc:XB-GENE-951823])

HSP 1 Score: 61.6178 bits (148), Expect = 2.089e-9
Identity = 35/110 (31.82%), Postives = 53/110 (48.18%), Query Frame = 3 
Query:  174 MEQYQFDIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCD 503
            ++ Y  + DP L    +C IC   L +A Q PCG  +CK CI K + ++   CP +++    ++L        DN A  ++  L V CP +GC     L  +  HL  CD
Sbjct:   55 VQGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACILKSIRDAGHKCPVDNESLMENQL------FPDNFAKREILSLRVKCPSQGCTETMELRHLERHLVRCD 158
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Mouse
Match: Traf6 (TNF receptor-associated factor 6 [Source:MGI Symbol;Acc:MGI:108072])

HSP 1 Score: 59.6918 bits (143), Expect = 5.884e-9
Identity = 37/135 (27.41%), Postives = 65/135 (48.15%), Query Frame = 3 
Query:  174 MEQYQFDIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCDKLPFWCPYAEIG---CTTNTMLTDE 569
            ++ Y  + DP L    +C IC   L +A Q PCG  +CK CI K + ++   CP +      +++ + + +  DN A  ++  L V CP +GC  +  L  + +H  +C+     CP  +     C  NT + ++
Sbjct:   53 IQGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVD------NEILLENQLFPDNFAKREILSLTVKCPNKGCLQKMELRHLEDHQVHCEFALVNCPQCQRPFQKCQVNTHIIED 181
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Mouse
Match: Traf5 (TNF receptor-associated factor 5 [Source:MGI Symbol;Acc:MGI:107548])

HSP 1 Score: 52.373 bits (124), Expect = 1.270e-6
Identity = 41/137 (29.93%), Postives = 62/137 (45.26%), Query Frame = 3 
Query:  180 QYQFDIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYLA-NSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICP-GEGCNFQSTLIEMSNHLQNCDKLPFWCPYAEIGCTTNTMLTDELVDHL 584
            +YQF    QL    KC  C+++L++  Q  CG  +C++CI      NS+  CP + +  K  +      + KDN    +V  L V C    GCN +  L    +HLQ+C      CP          ML  ++ +HL
Sbjct:   32 EYQFV--EQLEERYKCAFCHSVLHNPHQTGCGHRFCQQCIRSLRELNSVPICPVDKEVIKPQE------VFKDNCCKREVLNLHVYCKNAPGCNARIILGRFQDHLQHCSFQAVPCPNESC---REAMLRKDVKEHL 157
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Mouse
Match: Traf5 (TNF receptor-associated factor 5 [Source:MGI Symbol;Acc:MGI:107548])

HSP 1 Score: 52.373 bits (124), Expect = 1.270e-6
Identity = 41/137 (29.93%), Postives = 62/137 (45.26%), Query Frame = 3 
Query:  180 QYQFDIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYLA-NSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICP-GEGCNFQSTLIEMSNHLQNCDKLPFWCPYAEIGCTTNTMLTDELVDHL 584
            +YQF    QL    KC  C+++L++  Q  CG  +C++CI      NS+  CP + +  K  +      + KDN    +V  L V C    GCN +  L    +HLQ+C      CP          ML  ++ +HL
Sbjct:   32 EYQFV--EQLEERYKCAFCHSVLHNPHQTGCGHRFCQQCIRSLRELNSVPICPVDKEVIKPQE------VFKDNCCKREVLNLHVYCKNAPGCNARIILGRFQDHLQHCSFQAVPCPNESC---REAMLRKDVKEHL 157
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. UniProt/SwissProt
Match: sp|Q3ZCC3|TRAF6_BOVIN (TNF receptor-associated factor 6 OS=Bos taurus OX=9913 GN=TRAF6 PE=2 SV=1)

HSP 1 Score: 63.1586 bits (152), Expect = 3.394e-9
Identity = 35/117 (29.91%), Postives = 58/117 (49.57%), Query Frame = 3 
Query:  174 MEQYQFDIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCDKLPFWCP 524
            ++ Y  + DP L    +C IC   L +A Q PCG  +CK CI K + ++   CP +      +++ + + +  DN A  ++  L+V CP EGC  +  L  +  H  +C+     CP
Sbjct:   54 IQGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVD------NEILLENQLFPDNFAKREILSLMVKCPNEGCLHKMELRHLEEHQAHCEFALMSCP 164
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. UniProt/SwissProt
Match: sp|Q9Y4K3|TRAF6_HUMAN (TNF receptor-associated factor 6 OS=Homo sapiens OX=9606 GN=TRAF6 PE=1 SV=1)

HSP 1 Score: 63.1586 bits (152), Expect = 3.498e-9
Identity = 35/117 (29.91%), Postives = 59/117 (50.43%), Query Frame = 3 
Query:  174 MEQYQFDIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCDKLPFWCP 524
            ++ Y  + DP L    +C IC   L +A Q PCG  +CK CI K + ++   CP +      +++ + + +  DN A  ++  L+V CP EGC  +  L  + +H  +C+     CP
Sbjct:   53 IQGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVD------NEILLENQLFPDNFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALMDCP 163
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. UniProt/SwissProt
Match: sp|B6CJY4|TRAF6_CERAT (TNF receptor-associated factor 6 OS=Cercocebus atys OX=9531 GN=TRAF6 PE=2 SV=1)

HSP 1 Score: 62.7734 bits (151), Expect = 4.749e-9
Identity = 35/117 (29.91%), Postives = 59/117 (50.43%), Query Frame = 3 
Query:  174 MEQYQFDIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCDKLPFWCP 524
            ++ Y  + DP L    +C IC   L +A Q PCG  +CK CI K + ++   CP +      +++ + + +  DN A  ++  L+V CP EGC  +  L  + +H  +C+     CP
Sbjct:   53 IQGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVD------NEILLENQLFPDNFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALVDCP 163
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. UniProt/SwissProt
Match: sp|B6CJY5|TRAF6_MACMU (TNF receptor-associated factor 6 OS=Macaca mulatta OX=9544 GN=TRAF6 PE=2 SV=1)

HSP 1 Score: 62.3882 bits (150), Expect = 4.876e-9
Identity = 35/117 (29.91%), Postives = 59/117 (50.43%), Query Frame = 3 
Query:  174 MEQYQFDIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCDKLPFWCP 524
            ++ Y  + DP L    +C IC   L +A Q PCG  +CK CI K + ++   CP +      +++ + + +  DN A  ++  L+V CP EGC  +  L  + +H  +C+     CP
Sbjct:   53 IQGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVD------NEILLENQLFPDNFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALVDCP 163
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. UniProt/SwissProt
Match: sp|Q28DL4|TRAF6_XENTR (TNF receptor-associated factor 6 OS=Xenopus tropicalis OX=8364 GN=traf6 PE=2 SV=1)

HSP 1 Score: 61.6178 bits (148), Expect = 1.097e-8
Identity = 35/110 (31.82%), Postives = 53/110 (48.18%), Query Frame = 3 
Query:  174 MEQYQFDIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCD 503
            ++ Y  + DP L    +C IC   L +A Q PCG  +CK CI K + ++   CP +++    ++L        DN A  ++  L V CP +GC     L  +  HL  CD
Sbjct:   55 VQGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACILKSIRDAGHKCPVDNESLMENQL------FPDNFAKREILSLRVKCPSQGCTETMELRHLERHLVRCD 158
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. TrEMBL
Match: T1E101 (TRAF-6 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1)

HSP 1 Score: 130.954 bits (328), Expect = 2.875e-29
Identity = 90/351 (25.64%), Postives = 167/351 (47.58%), Query Frame = 3 
Query:  195 IDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCDKLPFWCPYAEIGCTTNTMLTDELVDHLQTEIVAHNNLLVKWITSAPDN-SHQPIAGDQETPIGKEMNNVFLTISD-VLSKKQVLINEMXXXXXXXXXXINELSKITKPIKALIDRNNKEMMSMKDANEKYISQIKFEISSEIKRVHLEFYQQNQISKKLEMELREIRGKLRKLETLTNSSRFRLKCTLEKLVKIA-----TFRWNIDNLKEIRNDGDDMIYSDYFYSINREYRMRLWVFPNGVGDNLG 1226
            +D  ++  + CI+CN L+ DAC+  CGC YC  CI  YL+ +  +CPG+  +CK   L++  ++ ++   + ++S+++V CP   CN+ S L+ +  HL  C      CP   IGC    +L DE+  HL  +++ H  L++ +        +H      ++    KE+  V   ++D   ++ + LI E+  K   +     ++ ++   +  L+     E+  +K   + +  +I+F       +  LE      I  +++   +EI G    +++  N  R R    L +L K+       F W I+   + R    D +YSD F S N ++ + L+++    GDNLG
Sbjct:   21 VDESVNNDLLCILCNKLMRDACESACGCHYCYTCIRIYLSQNHNYCPGDKTECKEDYLNLEGDVFRNIRLSTRISRIVVKCPNIRCNYTSELLRLKEHLDKCTPESVECPCVTIGCEEEPLLKDEMAKHLTDQVLRHTQLIMSFCNELKSEINHNNETTKEDISHLKEVLRVQKALNDEKTAQMEFLIEELRNKDNMILVLSQDIQEVKNEMITLLTSKESELKKLKSDIQIFRQEIEF------MKNDLEVVGSTDIKNQVKDLKKEIFGIKMNIDS-NNEERERKMNNLIRLNKLCPNVDMDFMWRIEEYSKKRRTVTD-VYSDSFQSHNYKFCLNLYIY----GDNLG 359
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. TrEMBL
Match: I1ZID8 (TNF receptor associated factor-2 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 114.005 bits (284), Expect = 2.653e-25
Identity = 54/156 (34.62%), Postives = 87/156 (55.77%), Query Frame = 3 
Query:  168 KMMEQYQFDIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCDKLPFWCPYAEIGCTTNTMLTDELVDHLQTEIVAHNNLLVKWITS 635
            +++  Y F+++  +   +KC +C NLL +ACQ  CGC +C KCI +Y++    +CPG   +CK   L I SNI  D   N K++K+ V CP E C     L+++  HL+ C      CP+  +GC    M+  +L +HLQ     H+ L++  I++
Sbjct:    8 RLLITYNFEVEGGVPDNLKCDLCKNLLVNACQSRCGCRFCSKCIMEYVSRGNLYCPGGTSECKEENLTICSNIHTDYRVNRKIAKMRVKCPEETCKVYCELVDIEEHLRLCTMKSQNCPFFVLGCNQPKMVIQDLTNHLQNGTFQHSKLIIDIISN 163
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. TrEMBL
Match: D5JG60 (TNF receptor-associated factor-2-like protein B OS=Dugesia japonica OX=6161 GN=TRAF-2B PE=2 SV=1)

HSP 1 Score: 91.6633 bits (226), Expect = 5.126e-16
Identity = 110/395 (27.85%), Postives = 173/395 (43.80%), Query Frame = 3 
Query:  219 VKCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCDKLPFWCPYAEIGCTT-NTMLTD-ELVDHLQT-------------EIVAHNNLLVKWITSAPDNSHQPIAGD--QETPIGKEMNNVFLTISDVLSKKQV--LINEMXXXXXXXXXXINELSKITKPIKALIDRNNKEMMSMKDANEKYISQIKFEISSEIKRVHLEFYQQNQISKKLEMELREIRGKLRKLETLTNSSRFRLKCTLEKLV-KIATFRWNIDNLKEIRNDGDD----MIYSDYFYSINREYRMRLWVFPNGVGDNLGNDISVQLLVWNNENDVATNNVSPKFPFKADITISI 1331
            +KCIIC+ LL +A Q  CGC YCK+C+ +Y A       G  K C +       NI+ DN+ N ++ KL V C   GC     L ++ +HL +       C +  I C + N  LT  EL +H +              E + ++NL    +    +     + G    +   GKE+N   L      SKK V  L +E+                +TK  + LI  NN+E +       K I  +K +I SE+K   LEF        K + E+ +    L K+   T+ S   ++ + EK V +   F W I+   E++++ +      I SDYFY+    Y+M + ++P G G   G  +SV   +   E D        ++PFK  +T++I
Sbjct:   28 LKCIICSQLLLEALQTDCGCRYCKECLKEYQAK------GKTK-CLTDGCGDLGNIIPDNAVNREIGKLTVKCLFPGCEHSELLKDIGDHLDS-------CIHQTINCKSCNEELTKIELKEHTEKKCPMRLVSCTHCGEEMEYSNLTELHLNVHTEKLCAKLVGKCPYKCDNGKEVN--LLDHRKSCSKKPVTCLFSEIGCNRV-----------MTK--EDLIKHNNEESLQHSRLLMKEIITMKNDI-SELKMKTLEFNILKIEFSKFQSEILDKIKSLEKIPRHTSPSTSSVRSSEEKTVYRNGVFIWKIERFSELKSEAERGNRISITSDYFYTKEFGYKMSMKIYPAGDGVGKGTHLSVFFTLMRGEFDDLL-----QWPFKNKVTLTI 387
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. TrEMBL
Match: T1DF65 (TRAF-2 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1)

HSP 1 Score: 84.3445 bits (207), Expect = 1.598e-13
Identity = 96/405 (23.70%), Postives = 175/405 (43.21%), Query Frame = 3 
Query:  219 VKCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVK-DNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCDKLPFWCPYAEIGCTTNTMLTDELVDHLQTEIVAHNNLLVKW-ITSAPDNSHQPIAGDQETPIGKEMNNVFLTISDVLSK----------KQVLIN----EMXXXXXXXXXXINELS-KITKPIKALIDRNNKE-------MMSMKDANEKYISQIKFEISSEIKRVHLEFYQQNQISKKLEMELREIRGKLRKLETL---TNSSRFRLKCTL-EKLVKIATFRWNIDNLKEIRNDG----DDMIYSDYFYSINREYRMRLWVFPNGVGDNLGNDISVQLLVWNNENDVATNNVSPKFPFKADITISIRN 1337
            + C+ C+ +L +  Q  CGC  C  C+++   +    CPG ++   S      SN  K D +   ++ +L +IC  +GC +   + ++ NHL+ C+       Y E  CT           + + E+  H     K  IT+  D   +   GD E    K+  NV   I +V SK          +  L+N     +  + + ++  +NE+  +   P + + +  N E       +M       K    +   +S + +R   E  +  +    L  E+ +++ KL++ +++     + R   KC+L E   +   + W ++N+ E  ND     +  I S+ FYS N  YRM L ++PNG G   GN +SV  ++   + D        ++PF + I+I + N
Sbjct:   30 ISCVKCHQVLIEPYQTQCGCRLCSNCLEECSKDEESHCPGCNETMNSP-----SNYSKHDKAIEKEILELNIICTNKGCEYTCKVKDLDNHLETCE-------YIEKRCTACNE------SYPRKELKKHEEFTCKMIITTCEDCGLELSKGDLE----KKHKNVNELIDNVCSKWRDICPFKCSEDTLVNIKDHLLTCERRPVECSLNEMGCRKVLPREEMREHFNLEANYHTVLLMDALFLLRKEHQDLSVSVSVQNERNSAEIKELKEKLSSLLTEIEDLKTKLKQFQSMYEKLENERNLAKCSLSETKERYGEYTWKVENIMEKVNDAKKGVNTQILSESFYSSNPGYRMCLKIYPNGDGSAFGNYLSVYFVLMKGKYDDQI-----QWPFNSIISIRLVN 407
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. TrEMBL
Match: T1DBK6 (TRAF-4 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1)

HSP 1 Score: 82.0333 bits (201), Expect = 7.532e-13
Identity = 42/108 (38.89%), Postives = 64/108 (59.26%), Query Frame = 3 
Query:  180 QYQFDIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCD 503
            +++F I+  L    KC++C ++L DA Q  CGC YCK+CID YL N  K C   ++DC+S    + ++ + D + N ++S L V C  EGC F+ TL  +  HL  C+
Sbjct:   20 KWRFTINDNL----KCVMCQDILLDAIQTDCGCRYCKECIDNYLENGEKECVAEYEDCRS----VITSYIYDRATNKEISLLKVKCLYEGCVFEDTLKSIKGHLDFCE 119
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Cavefish
Match: traf1 (TNF receptor-associated factor 1-like [Source:NCBI gene;Acc:103045252])

HSP 1 Score: 61.2326 bits (147), Expect = 1.510e-9
Identity = 43/139 (30.94%), Postives = 66/139 (47.48%), Query Frame = 3 
Query:  192 DIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFC-------PGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCDKLPFWCPYAEIGCTTNTMLTDELVDHLQ 587
            D+ P   ++  C  CNN+LN+A Q  CG  YC+ C+   L N+           PG+  D  SS +    +   DN+ N ++ +L V C  +GC ++STL +  +H   C+     C    IGC    +L   L  HL+
Sbjct:   21 DLPP---VHFLCSSCNNVLNEAHQTQCGHRYCRACVMWLLRNNKDLICTKCKEDPGSESD--SSMMLTLDHFFSDNAINKEIQELRVHCVNQGCGWRSTLKDFEDHQSQCEYALIPC---NIGCGL-MVLRKTLATHLE 150
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Cavefish
Match: traf1 (TNF receptor-associated factor 1-like [Source:NCBI gene;Acc:103045252])

HSP 1 Score: 61.2326 bits (147), Expect = 1.525e-9
Identity = 43/139 (30.94%), Postives = 66/139 (47.48%), Query Frame = 3 
Query:  192 DIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFC-------PGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCDKLPFWCPYAEIGCTTNTMLTDELVDHLQ 587
            D+ P   ++  C  CNN+LN+A Q  CG  YC+ C+   L N+           PG+  D  SS +    +   DN+ N ++ +L V C  +GC ++STL +  +H   C+     C    IGC    +L   L  HL+
Sbjct:   21 DLPP---VHFLCSSCNNVLNEAHQTQCGHRYCRACVMWLLRNNKDLICTKCKEDPGSESD--SSMMLTLDHFFSDNAINKEIQELRVHCVNQGCGWRSTLKDFEDHQSQCEYALIPC---NIGCGL-MVLRKTLATHLE 150
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Cavefish
Match: traf6 (TNF receptor associated factor 6 [Source:NCBI gene;Acc:103021325])

HSP 1 Score: 57.7658 bits (138), Expect = 1.898e-8
Identity = 39/137 (28.47%), Postives = 60/137 (43.80%), Query Frame = 3 
Query:  183 YQFDIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCDKLPFWCPYAEIGCTTNTMLTDELVDHLQTE 593
            Y  D DP L    +C IC   L  A Q PCG  +C  CI K + ++ + CP +++     +L        DN A  ++  L V C   GC  +  L  + NH+ +C      CP  +      ++   EL +H+  E
Sbjct:   56 YDVDFDPPLESKYECPICLMGLRSAVQTPCGHRFCNCCIRKSIRDTGQKCPVDNEVLTEDQL------FPDNFAKREILSLTVRCRNVGCMEKMELRHLENHIPHCKFATVPCPQCQ-----ESVWKSELEEHINQE 181
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Cavefish
Match: traf6 (TNF receptor associated factor 6 [Source:NCBI gene;Acc:103021325])

HSP 1 Score: 57.3806 bits (137), Expect = 2.521e-8
Identity = 39/137 (28.47%), Postives = 60/137 (43.80%), Query Frame = 3 
Query:  183 YQFDIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCDKLPFWCPYAEIGCTTNTMLTDELVDHLQTE 593
            Y  D DP L    +C IC   L  A Q PCG  +C  CI K + ++ + CP +++     +L        DN A  ++  L V C   GC  +  L  + NH+ +C      CP  +      ++   EL +H+  E
Sbjct:   56 YDVDFDPPLESKYECPICLMGLRSAVQTPCGHRFCNCCIRKSIRDTGQKCPVDNEVLTEDQL------FPDNFAKREILSLTVRCRNVGCMEKMELRHLENHIPHCKFATVPCPQCQ-----ESVWKSELEEHINQE 181
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Cavefish
Match: traf6 (TNF receptor associated factor 6 [Source:NCBI gene;Acc:103021325])

HSP 1 Score: 57.3806 bits (137), Expect = 2.521e-8
Identity = 39/137 (28.47%), Postives = 60/137 (43.80%), Query Frame = 3 
Query:  183 YQFDIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCDKLPFWCPYAEIGCTTNTMLTDELVDHLQTE 593
            Y  D DP L    +C IC   L  A Q PCG  +C  CI K + ++ + CP +++     +L        DN A  ++  L V C   GC  +  L  + NH+ +C      CP  +      ++   EL +H+  E
Sbjct:   56 YDVDFDPPLESKYECPICLMGLRSAVQTPCGHRFCNCCIRKSIRDTGQKCPVDNEVLTEDQL------FPDNFAKREILSLTVRCRNVGCMEKMELRHLENHIPHCKFATVPCPQCQ-----ESVWKSELEEHINQE 181
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Sea Lamprey
Match: traf6 (TNF receptor-associated factor 6 [Source:NCBI gene;Acc:554561])

HSP 1 Score: 50.8322 bits (120), Expect = 5.468e-7
Identity = 34/129 (26.36%), Postives = 54/129 (41.86%), Query Frame = 3 
Query:  177 EQYQFDIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCI--DKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCDKLPFWCPYAEIGCTTNTM 557
            + Y+ D +P L    +C IC   L +  Q PCG  +C+ CI     L ++   CP ++      +L        DN A  ++  L V CP + C  +  L  +  H   C+       YA++ C    M
Sbjct:   49 QGYEADFEPPLESKYECPICLMALREPVQTPCGHRFCRACILHSMRLRDAGPKCPVDNAVLHEGQL------FPDNFAKREILSLTVRCPNKPCGHRGELRALQEHQLRCE-------YAQVPCVRCEM 164
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Sea Lamprey
Match: rnf41l (ring finger protein 41, like [Source:ZFIN;Acc:ZDB-GENE-030131-9441])

HSP 1 Score: 46.2098 bits (108), Expect = 1.291e-6
Identity = 29/110 (26.36%), Postives = 50/110 (45.45%), Query Frame = 3 
Query:  225 CIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICP--GEGCNFQSTLIEMSNHLQNCDKLPFWCPY-AEIGCT 545
            C +C ++L D  Q PC   +C  CI  +L ++   CP + +   +S+L      ++     N ++ L + C     GC     L  ++ H Q C   P  CP+  E+ C+
Sbjct:   18 CCVCRDVLEDPLQAPCEHAFCSACIHGWLVHNHT-CPEDRQPLDASELRPLFRYMR-----NDLNALRLHCTHRARGCEGVCALETIAIHEQQCPYTPTPCPHTGELACS 121
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Nematostella
Match: EDO48394 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJK8])

HSP 1 Score: 64.6994 bits (156), Expect = 3.814e-11
Identity = 93/424 (21.93%), Postives = 166/424 (39.15%), Query Frame = 3 
Query:  186 QFDIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYL-ANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCDKLPFWCPYAEIGCTTNTMLTDELVDHLQTEIVAHNNLLVKWIT-SAPDNSHQPIAGDQETPI---------------GKEMNNVFLTISDVLSKKQVLINEMXXXXXXXXXXINELSKITKPIKALIDRNNKEMMSMKDANEKYISQIKFEISSEIKR-------VHLEFYQQNQISKKLEMELREIRGKLRKLETLTNSSRFRL------------KCTLEKLVKIATFR----WNIDNLKEIRNDGDDMIYSDYFYSINREYRMRLWVFPNGVGDNLGNDISVQLLVWNNENDVATNNVSPKFPFKADITISIRN 1337
            QF I P   +   C IC+ ++N+     CG  YCK CI+K+     +  CP +++  K S+      I  D   +  V  L V C    C ++  L +   HL+ C      C     GC         ++    T       L  K    S P    + +    + P+               G+E        S V +   +    +    + + +   EL K+ + ++     + KE+ ++++ +++ I   K +I +  K        +H    Q + + K+L +    IR    ++  L+ + + +             K   +K V  AT +     N D+  +I   GD M+ S  FY+    Y+MRL  +PNG GD  G  +S+ + +   E D        ++PF+  IT+S+ N
Sbjct:   19 QFIIPPNDELI--CAICHMVVNEPVLTSCGHSYCKYCIEKWCNGKEVVTCPVDNEQLKPSQ------IFPDKKTDRIVLSLEVKCTNNPCRWKGELRQKQKHLKICSHKAVKCILE--GCNVKV---PRILMEKHTNTCGWRLLHCKPCNLSYPKKDEETVQHKDDCPLAFLPCRFSEIGCTFKGRESARDEHCESAVQTHLHIACETIRDNKEQISDLHKELDKVRQELQTKSCDHMKEVNAIREKHDEAIRDNKGQIEALSKEHGIASNTIHENKEQLDTLKKELGIASETIRKNRDQIAKLSTACKTQYTDGTFVWRICNYKDKYKKAVAFATNQEVKGGNSDSDDDISMAGDIMV-SLPFYTSRYGYKMRLKAYPNGYGDGKGTHLSLSIRIMKGEYDAIL-----EWPFRRKITLSLIN 423
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Nematostella
Match: EDO48773 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RI91])

HSP 1 Score: 53.9138 bits (128), Expect = 9.897e-8
Identity = 36/127 (28.35%), Postives = 55/127 (43.31%), Query Frame = 3 
Query:  153 YLFMWKMMEQYQFDIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVIC---PGEGCNFQSTLIEMSNHLQNCDKLPFWCP 524
            Y    ++ E Y    DP L    +C IC   L D  Q PCG  +C  CI + + ++   CP ++      +L       +DN A  ++   IV C      GC ++  L E+  HL+ C  +   CP
Sbjct:   34 YGGPQRLEEGYDEFFDPPLESKYECPICLLGLRDPVQTPCGHRFCFNCIRRSIRDAGPKCPVDNTPLSEREL------YRDNFAKREMMSFIVWCRLKKERGCTWKGALKELEEHLKGCPCMDTNCP 154
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Nematostella
Match: EDO41243 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4Z7])

HSP 1 Score: 50.447 bits (119), Expect = 1.313e-6
Identity = 28/94 (29.79%), Postives = 48/94 (51.06%), Query Frame = 3 
Query:  225 CIICNNLLNDACQGPCGCLYCKKCIDKY-LANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCD 503
            C IC+  L    Q  CG  +CK+C+D+     S   CP + +      LD+  ++  D +A   +   +V CP +GC +++ L ++  H +NCD
Sbjct:   25 CRICHLPLRVPVQTKCGHRFCKECLDEASRRKSRAECPMDRE-----PLDLKKDVFLDKAAERTILSFLVKCPCKGCKWEAELRDLEAHARNCD 113
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Nematostella
Match: EDO34728 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNG3])

HSP 1 Score: 47.7506 bits (112), Expect = 1.531e-6
Identity = 35/119 (29.41%), Postives = 53/119 (44.54%), Query Frame = 3 
Query:  189 FDIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVIC--PGEGCNFQSTLIEMSNHLQNCDKLPFWCPYAEIG 539
             D+ P+L     C IC  +L D  + PC  ++C +CI K+L N+   CP      ++  L     +V+     N +SKL + C    +GC    +L  +  H   C   P  C YA  G
Sbjct:    9 VDVSPELV----CCICTGVLEDPVESPCRHVFCSECISKWLQNNSN-CPTCRSQVRAKNLKPVLPLVR-----NIISKLKIHCDFKTQGCKAIVSLESLRRHATICVMAPVTCTYANCG 117
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Nematostella
Match: EDO27426 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T9A1])

HSP 1 Score: 46.9802 bits (110), Expect = 3.812e-6
Identity = 27/96 (28.12%), Postives = 48/96 (50.00%), Query Frame = 3 
Query:  225 CIICNNLLNDACQGPCGCLYCKKCIDKY-LANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCDKL 509
            C IC+  L    Q  CG  +CK+C+D+     S   CP + +      LD+  ++  D +A   +   +V CP +GC +++ L ++   ++ C KL
Sbjct:   25 CRICHLPLRVPVQTKCGHRFCKECLDEASRRKSRAECPMDREP-----LDLKKDVFLDKAAERTILSFLVKCPCKGCKWEAELRDLEVSMKGCGKL 115
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Medaka
Match: traf6 (TNF receptor associated factor 6 [Source:NCBI gene;Acc:101161132])

HSP 1 Score: 55.8398 bits (133), Expect = 8.134e-8
Identity = 32/109 (29.36%), Postives = 51/109 (46.79%), Query Frame = 3 
Query:  174 MEQYQFDIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNC 500
            ++ Y  + DP L    +C IC   L +A Q  CG  +CK CI+K + ++ + CP +++     +L        DN A  ++  L V CP   C  +  L  +  HL  C
Sbjct:   61 LQGYDVEFDPPLESKYECPICLMALRNAIQTRCGHRFCKSCIEKSIRDTGQRCPVDNEMLSEDQL------FPDNFAKREILSLTVRCPNSDCGEKMELRHLEKHLAQC 163
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. Planmine SMEST
Match: SMESG000012339.1 (SMESG000012339.1)

HSP 1 Score: 904.82 bits (2337), Expect = 0.000e+0
Identity = 449/451 (99.56%), Postives = 449/451 (99.56%), Query Frame = 3 
Query:  144 MAHYLFMWKMMEQYQFDIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCDKLPFWCPYAEIGCTTNTMLTDELVDHLQTEIVAHNNLLVKWITSAPDNSHQPIAGDQETPIGKEMNNVFLTISDVLSKKQVLINEMXXXXXXXXXXINELSKITKPIKALIDRNNKEMMSMKDANEKYISQIKFEISSEIKRVHLEFYQQNQISKKLEMELREIRGKLRKLETLTNSSRFRLKCTLEKLVKIATFRWNIDNLKEIRNDGDDMIYSDYFYSINREYRMRLWVFPNGVGDNLGNDISVQLLVWNNENDVATNNVSPKFPFKADITISIRNSIKPQIYQSISQLSLLDRPNLFLYTTSELFNFNYTHLNLGGVFANQFSTVECA 1496
            MAHYLFMWKMMEQYQFDIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCDKLPFWCPYAEIGCTTNTMLTDELVDHLQTEIVAHNNLLVKWITSA DNSHQPIAGDQETPIGKEMNNVFLTISDVLSKKQVLINEMLKKLKDLKEKINELSKITKPIKALIDRNNKEMMSMKDANEKYISQIKFEISSEIKRVHLEFYQQNQISKKLEMELREIRGKLRKLETLTNSSRFRLKCTLEKLVKIATFRWNIDNLKEIRNDGDDMIYSDYFYSINREYRMRLWVFPNGVGDNLGNDISVQLLVWNNENDVATNNVS KFPFKADITISIRNSIKPQIYQSISQLSLLDRPNLFLYTTSELFNFNYTHLNLGGVFANQFSTVECA
Sbjct:    1 MAHYLFMWKMMEQYQFDIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCDKLPFWCPYAEIGCTTNTMLTDELVDHLQTEIVAHNNLLVKWITSASDNSHQPIAGDQETPIGKEMNNVFLTISDVLSKKQVLINEMLKKLKDLKEKINELSKITKPIKALIDRNNKEMMSMKDANEKYISQIKFEISSEIKRVHLEFYQQNQISKKLEMELREIRGKLRKLETLTNSSRFRLKCTLEKLVKIATFRWNIDNLKEIRNDGDDMIYSDYFYSINREYRMRLWVFPNGVGDNLGNDISVQLLVWNNENDVATNNVSTKFPFKADITISIRNSIKPQIYQSISQLSLLDRPNLFLYTTSELFNFNYTHLNLGGVFANQFSTVECA 451
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. Planmine SMEST
Match: SMESG000012339.1 (SMESG000012339.1)

HSP 1 Score: 889.412 bits (2297), Expect = 0.000e+0
Identity = 443/445 (99.55%), Postives = 443/445 (99.55%), Query Frame = 3 
Query:  162 MWKMMEQYQFDIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCDKLPFWCPYAEIGCTTNTMLTDELVDHLQTEIVAHNNLLVKWITSAPDNSHQPIAGDQETPIGKEMNNVFLTISDVLSKKQVLINEMXXXXXXXXXXINELSKITKPIKALIDRNNKEMMSMKDANEKYISQIKFEISSEIKRVHLEFYQQNQISKKLEMELREIRGKLRKLETLTNSSRFRLKCTLEKLVKIATFRWNIDNLKEIRNDGDDMIYSDYFYSINREYRMRLWVFPNGVGDNLGNDISVQLLVWNNENDVATNNVSPKFPFKADITISIRNSIKPQIYQSISQLSLLDRPNLFLYTTSELFNFNYTHLNLGGVFANQFSTVECA 1496
            MWKMMEQYQFDIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCDKLPFWCPYAEIGCTTNTMLTDELVDHLQTEIVAHNNLLVKWITSA DNSHQPIAGDQETPIGKEMNNVFLTISDVLSKKQVLINEMLKKLKDLKEKINELSKITKPIKALIDRNNKEMMSMKDANEKYISQIKFEISSEIKRVHLEFYQQNQISKKLEMELREIRGKLRKLETLTNSSRFRLKCTLEKLVKIATFRWNIDNLKEIRNDGDDMIYSDYFYSINREYRMRLWVFPNGVGDNLGNDISVQLLVWNNENDVATNNVS KFPFKADITISIRNSIKPQIYQSISQLSLLDRPNLFLYTTSELFNFNYTHLNLGGVFANQFSTVECA
Sbjct:    1 MWKMMEQYQFDIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCDKLPFWCPYAEIGCTTNTMLTDELVDHLQTEIVAHNNLLVKWITSASDNSHQPIAGDQETPIGKEMNNVFLTISDVLSKKQVLINEMLKKLKDLKEKINELSKITKPIKALIDRNNKEMMSMKDANEKYISQIKFEISSEIKRVHLEFYQQNQISKKLEMELREIRGKLRKLETLTNSSRFRLKCTLEKLVKIATFRWNIDNLKEIRNDGDDMIYSDYFYSINREYRMRLWVFPNGVGDNLGNDISVQLLVWNNENDVATNNVSTKFPFKADITISIRNSIKPQIYQSISQLSLLDRPNLFLYTTSELFNFNYTHLNLGGVFANQFSTVECA 445
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. Planmine SMEST
Match: SMESG000012339.1 (SMESG000012339.1)

HSP 1 Score: 882.478 bits (2279), Expect = 0.000e+0
Identity = 440/442 (99.55%), Postives = 440/442 (99.55%), Query Frame = 3 
Query:  171 MMEQYQFDIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCDKLPFWCPYAEIGCTTNTMLTDELVDHLQTEIVAHNNLLVKWITSAPDNSHQPIAGDQETPIGKEMNNVFLTISDVLSKKQVLINEMXXXXXXXXXXINELSKITKPIKALIDRNNKEMMSMKDANEKYISQIKFEISSEIKRVHLEFYQQNQISKKLEMELREIRGKLRKLETLTNSSRFRLKCTLEKLVKIATFRWNIDNLKEIRNDGDDMIYSDYFYSINREYRMRLWVFPNGVGDNLGNDISVQLLVWNNENDVATNNVSPKFPFKADITISIRNSIKPQIYQSISQLSLLDRPNLFLYTTSELFNFNYTHLNLGGVFANQFSTVECA 1496
            MMEQYQFDIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCDKLPFWCPYAEIGCTTNTMLTDELVDHLQTEIVAHNNLLVKWITSA DNSHQPIAGDQETPIGKEMNNVFLTISDVLSKKQVLINEMLKKLKDLKEKINELSKITKPIKALIDRNNKEMMSMKDANEKYISQIKFEISSEIKRVHLEFYQQNQISKKLEMELREIRGKLRKLETLTNSSRFRLKCTLEKLVKIATFRWNIDNLKEIRNDGDDMIYSDYFYSINREYRMRLWVFPNGVGDNLGNDISVQLLVWNNENDVATNNVS KFPFKADITISIRNSIKPQIYQSISQLSLLDRPNLFLYTTSELFNFNYTHLNLGGVFANQFSTVECA
Sbjct:    1 MMEQYQFDIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCDKLPFWCPYAEIGCTTNTMLTDELVDHLQTEIVAHNNLLVKWITSASDNSHQPIAGDQETPIGKEMNNVFLTISDVLSKKQVLINEMLKKLKDLKEKINELSKITKPIKALIDRNNKEMMSMKDANEKYISQIKFEISSEIKRVHLEFYQQNQISKKLEMELREIRGKLRKLETLTNSSRFRLKCTLEKLVKIATFRWNIDNLKEIRNDGDDMIYSDYFYSINREYRMRLWVFPNGVGDNLGNDISVQLLVWNNENDVATNNVSTKFPFKADITISIRNSIKPQIYQSISQLSLLDRPNLFLYTTSELFNFNYTHLNLGGVFANQFSTVECA 442
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. Planmine SMEST
Match: SMESG000009561.1 (SMESG000009561.1)

HSP 1 Score: 177.563 bits (449), Expect = 9.755e-50
Identity = 126/457 (27.57%), Postives = 217/457 (47.48%), Query Frame = 3 
Query:  144 MAHYLFMWKMMEQYQFDIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCDKLPFWCPYAEIGCTTNTMLTDELVDHLQTEIVAHNNLLVKWITSAPDNSHQPIAGDQETPIGKEMNNVFLTISDVLSKKQVLINEMXXXXXXXXXXINELSKITKPIKALIDRNNKEMMSMKDANEKYISQIKFEISS-EIKRVHLEFYQQNQISKKLEMELR---EIRGKLRKLETLTNSSRFRLKCTLEKLVKIATFRWNIDNLKEIRNDGDDMIYSDYFYSINREYRMRLWVFPNGVGDNLGNDISVQLLV--WNNENDVATNNVSPKFPFKADITISIRNSIKPQIYQSISQLSLLDRPNLFLYTTSELFNFNYTHLNLGGVFANQFSTVECA 1496
            M   + MW ++++Y F+IDP++ IYVKC ICN LL +A QGPC C YCK CI+ YL +  K CPG+  +C+  ++ + ++I+KD  A+ +VS+L V CP   C FQ  L+ M +HL+ C+K P  CP+ E+GC T       + DHL   I  H+ L+  WIT   + +      + E    K++ N       VL +  +++ +          +  E+  + + I+    +  K    +++  + Y  +I F  +  E +R+ +    +N+  K L +        R  + K  ++    R  L C ++  +  A+  W +  +   +      + S+ F+S +R+++M L ++P G     G  +S+   +  W         N S  FPFK +I + I N  +      IS        NL     SE+F+F+   L    V  +    +EC+
Sbjct:    1 MEKLVKMWTILDKYPFEIDPKVLIYVKCSICNGLLRNAYQGPCCCNYCKTCIEIYLGDDRKHCPGDSIECRQEQISMRNHIIKDRGADYRVSQLDVRCPWNSCRFQGKLLNMDDHLRTCNKSPIECPFTELGCQTILTENINIKDHLLDNICQHSKLISNWITILKNET-----LNCEGSAIKQLRN-------VLKQNVIVLVDRKISQVRCNLRNAEIEPLLEKIQIESIKREKLKDEIRNLEKDYGQKILFHKNELEKQRILIRKLMKNKHHKNLALSKESGNHDRKCISKFNSIQQHGRDDL-CGVKSEMA-ASLSWIVTEISR-KTKYKINLKSENFHSNDRQFQMNLLLYPGGYERYTGTHLSIAFYIRPW------KAVNPSKLFPFKCNILMRISNKFQTNSQLDISNNCQFKSQNL----NSEIFHFSLDELEQTAVTYSDTVVIECS 432
[Close]
BLAST of V(D)J recombination-activating protein 1 vs. Planmine SMEST
Match: SMESG000009561.1 (SMESG000009561.1)

HSP 1 Score: 176.407 bits (446), Expect = 1.871e-49
Identity = 125/451 (27.72%), Postives = 215/451 (47.67%), Query Frame = 3 
Query:  162 MWKMMEQYQFDIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKKCIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPGEGCNFQSTLIEMSNHLQNCDKLPFWCPYAEIGCTTNTMLTDELVDHLQTEIVAHNNLLVKWITSAPDNSHQPIAGDQETPIGKEMNNVFLTISDVLSKKQVLINEMXXXXXXXXXXINELSKITKPIKALIDRNNKEMMSMKDANEKYISQIKFEISS-EIKRVHLEFYQQNQISKKLEMELR---EIRGKLRKLETLTNSSRFRLKCTLEKLVKIATFRWNIDNLKEIRNDGDDMIYSDYFYSINREYRMRLWVFPNGVGDNLGNDISVQLLV--WNNENDVATNNVSPKFPFKADITISIRNSIKPQIYQSISQLSLLDRPNLFLYTTSELFNFNYTHLNLGGVFANQFSTVECA 1496
            MW ++++Y F+IDP++ IYVKC ICN LL +A QGPC C YCK CI+ YL +  K CPG+  +C+  ++ + ++I+KD  A+ +VS+L V CP   C FQ  L+ M +HL+ C+K P  CP+ E+GC T       + DHL   I  H+ L+  WIT   + +      + E    K++ N       VL +  +++ +          +  E+  + + I+    +  K    +++  + Y  +I F  +  E +R+ +    +N+  K L +        R  + K  ++    R  L C ++  +  A+  W +  +   +      + S+ F+S +R+++M L ++P G     G  +S+   +  W         N S  FPFK +I + I N  +      IS        NL     SE+F+F+   L    V  +    +EC+
Sbjct:    1 MWTILDKYPFEIDPKVLIYVKCSICNGLLRNAYQGPCCCNYCKTCIEIYLGDDRKHCPGDSIECRQEQISMRNHIIKDRGADYRVSQLDVRCPWNSCRFQGKLLNMDDHLRTCNKSPIECPFTELGCQTILTENINIKDHLLDNICQHSKLISNWITILKNET-----LNCEGSAIKQLRN-------VLKQNVIVLVDRKISQVRCNLRNAEIEPLLEKIQIESIKREKLKDEIRNLEKDYGQKILFHKNELEKQRILIRKLMKNKHHKNLALSKESGNHDRKCISKFNSIQQHGRDDL-CGVKSEMA-ASLSWIVTEISR-KTKYKINLKSENFHSNDRQFQMNLLLYPGGYERYTGTHLSIAFYIRPW------KAVNPSKLFPFKCNILMRISNKFQTNSQLDISNNCQFKSQNL----NSEIFHFSLDELEQTAVTYSDTVVIECS 426
The following BLAST results are available for this feature:
BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 4
Match NameE-valueIdentityDescription
TRAF67.284e-1029.91TNF receptor associated factor 6 [Source:HGNC Symb... [more]
TRAF67.284e-1029.91TNF receptor associated factor 6 [Source:HGNC Symb... [more]
TRAF25.651e-630.77TNF receptor associated factor 2 [Source:HGNC Symb... [more]
TRAF27.744e-631.03TNF receptor associated factor 2 [Source:HGNC Symb... [more]
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BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Traf61.180e-925.32gene:FBgn0265464 transcript:FBtr0071188[more]
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BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
traf61.068e-728.95TNF receptor-associated factor 6 [Source:NCBI gene... [more]
traf61.068e-728.95TNF receptor-associated factor 6 [Source:NCBI gene... [more]
traf61.068e-728.95TNF receptor-associated factor 6 [Source:NCBI gene... [more]
rnf416.421e-625.15ring finger protein 41 [Source:NCBI gene;Acc:40683... [more]
rnf416.421e-625.15ring finger protein 41 [Source:NCBI gene;Acc:40683... [more]
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BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
egf2.089e-931.82epidermal growth factor [Source:Xenbase;Acc:XB-GEN... [more]
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BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Traf65.884e-927.41TNF receptor-associated factor 6 [Source:MGI Symbo... [more]
Traf51.270e-629.93TNF receptor-associated factor 5 [Source:MGI Symbo... [more]
Traf51.270e-629.93TNF receptor-associated factor 5 [Source:MGI Symbo... [more]
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BLAST of V(D)J recombination-activating protein 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q3ZCC3|TRAF6_BOVIN3.394e-929.91TNF receptor-associated factor 6 OS=Bos taurus OX=... [more]
sp|Q9Y4K3|TRAF6_HUMAN3.498e-929.91TNF receptor-associated factor 6 OS=Homo sapiens O... [more]
sp|B6CJY4|TRAF6_CERAT4.749e-929.91TNF receptor-associated factor 6 OS=Cercocebus aty... [more]
sp|B6CJY5|TRAF6_MACMU4.876e-929.91TNF receptor-associated factor 6 OS=Macaca mulatta... [more]
sp|Q28DL4|TRAF6_XENTR1.097e-831.82TNF receptor-associated factor 6 OS=Xenopus tropic... [more]
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BLAST of V(D)J recombination-activating protein 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
T1E1012.875e-2925.64TRAF-6 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1[more]
I1ZID82.653e-2534.62TNF receptor associated factor-2 (Fragment) OS=Sch... [more]
D5JG605.126e-1627.85TNF receptor-associated factor-2-like protein B OS... [more]
T1DF651.598e-1323.70TRAF-2 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1[more]
T1DBK67.532e-1338.89TRAF-4 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1[more]
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BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
traf11.510e-930.94TNF receptor-associated factor 1-like [Source:NCBI... [more]
traf11.525e-930.94TNF receptor-associated factor 1-like [Source:NCBI... [more]
traf61.898e-828.47TNF receptor associated factor 6 [Source:NCBI gene... [more]
traf62.521e-828.47TNF receptor associated factor 6 [Source:NCBI gene... [more]
traf62.521e-828.47TNF receptor associated factor 6 [Source:NCBI gene... [more]
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BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
traf65.468e-726.36TNF receptor-associated factor 6 [Source:NCBI gene... [more]
rnf41l1.291e-626.36ring finger protein 41, like [Source:ZFIN;Acc:ZDB-... [more]
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BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO483943.814e-1121.93Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO487739.897e-828.35Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO412431.313e-629.79Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO347281.531e-629.41Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO274263.812e-628.13Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of V(D)J recombination-activating protein 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
traf68.134e-829.36TNF receptor associated factor 6 [Source:NCBI gene... [more]
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BLAST of V(D)J recombination-activating protein 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000012339.10.000e+099.56SMESG000012339.1[more]
SMESG000012339.10.000e+099.55SMESG000012339.1[more]
SMESG000012339.10.000e+099.55SMESG000012339.1[more]
SMESG000009561.19.755e-5027.57SMESG000009561.1[more]
SMESG000009561.11.871e-4927.72SMESG000009561.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30021059 ID=SMED30021059|Name=V(D)J recombination-activating protein 1|organism=Schmidtea mediterranea sexual|type=transcript|length=1593bp
CAAGTGTCAGCCATTGATGAAACACAATTTTATTTATATAGTAAACTTCA
TCATAAAGATGTCATGATACGTTACCACATCGACATCAGTAATTAAATAA
TATTTTATGTTGACTTAACCTCAAATACCCAGCAGAATTTCGAATGGCAC
ATTATTTGTTCATGTGGAAAATGATGGAGCAATACCAATTTGACATTGAT
CCGCAACTCTCCATTTATGTCAAATGCATTATTTGTAACAATCTCTTAAA
TGACGCTTGCCAAGGACCTTGTGGATGTCTTTATTGCAAGAAATGTATCG
ACAAATATTTAGCGAACTCTATGAAATTTTGCCCCGGTAATCACAAAGAT
TGCAAATCATCAAAGCTGGATATTTTTAGCAATATCGTCAAAGATAACAG
TGCCAACAACAAAGTGTCAAAATTAATAGTCATATGTCCCGGGGAGGGTT
GTAATTTCCAAAGCACATTAATCGAAATGAGCAACCATCTACAGAATTGT
GATAAACTGCCATTTTGGTGTCCGTATGCTGAAATTGGATGCACTACCAA
TACAATGTTAACGGATGAATTAGTAGACCACCTACAAACCGAAATAGTCG
CTCATAATAATCTCCTAGTTAAATGGATAACTAGTGCGCCAGATAATTCT
CATCAGCCAATCGCAGGTGACCAAGAAACGCCAATTGGAAAAGAAATGAA
TAATGTTTTCCTTACCATATCAGATGTTTTGTCAAAAAAACAGGTTCTCA
TTAATGAAATGCTGAAAAAGTTGAAGGATTTGAAAGAGAAAATTAATGAA
TTATCGAAAATAACGAAACCGATAAAGGCACTAATCGACAGAAACAATAA
AGAAATGATGTCAATGAAAGATGCAAATGAAAAATACATTTCTCAAATTA
AATTCGAGATTTCTTCGGAAATCAAACGAGTTCATCTGGAATTTTATCAG
CAAAATCAAATTAGTAAAAAATTGGAGATGGAATTGCGTGAAATTCGTGG
GAAATTGAGAAAACTGGAAACTTTGACGAATTCGTCTCGTTTCAGGTTGA
AATGCACTTTGGAAAAACTCGTCAAAATCGCGACGTTTAGATGGAATATT
GATAACCTCAAAGAAATAAGAAACGATGGAGACGACATGATTTATAGCGA
TTATTTTTATAGCATTAATCGGGAATATAGGATGAGGTTATGGGTCTTTC
CCAATGGAGTTGGAGACAATCTTGGAAATGATATCTCAGTTCAATTGCTT
GTTTGGAACAATGAAAACGACGTCGCTACTAATAATGTTTCCCCAAAATT
TCCTTTCAAAGCTGATATCACAATTTCCATTCGAAATTCAATCAAACCTC
AAATATATCAGAGTATATCACAATTGAGTTTACTTGATAGACCAAACTTA
TTTCTTTATACTACGTCGGAACTCTTTAATTTTAATTACACCCATCTTAA
TTTAGGAGGGGTGTTTGCAAATCAGTTCTCGACGGTCGAATGTGCGATTT
CAATTTATAAATAAATTATAATTCATTACTTGATTTTGTAAAGATTGGCA
GTTTGTGGGATTTGGAGCCCCCGTGTAAGAATTACAAGGTGCA
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protein sequence of SMED30021059-orf-1

>SMED30021059-orf-1 ID=SMED30021059-orf-1|Name=SMED30021059-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=457bp
MAHYLFMWKMMEQYQFDIDPQLSIYVKCIICNNLLNDACQGPCGCLYCKK
CIDKYLANSMKFCPGNHKDCKSSKLDIFSNIVKDNSANNKVSKLIVICPG
EGCNFQSTLIEMSNHLQNCDKLPFWCPYAEIGCTTNTMLTDELVDHLQTE
IVAHNNLLVKWITSAPDNSHQPIAGDQETPIGKEMNNVFLTISDVLSKKQ
VLINEMLKKLKDLKEKINELSKITKPIKALIDRNNKEMMSMKDANEKYIS
QIKFEISSEIKRVHLEFYQQNQISKKLEMELREIRGKLRKLETLTNSSRF
RLKCTLEKLVKIATFRWNIDNLKEIRNDGDDMIYSDYFYSINREYRMRLW
VFPNGVGDNLGNDISVQLLVWNNENDVATNNVSPKFPFKADITISIRNSI
KPQIYQSISQLSLLDRPNLFLYTTSELFNFNYTHLNLGGVFANQFSTVEC
AISIYK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0003677DNA binding
GO:0003824catalytic activity
GO:0004518nuclease activity
GO:0004519endonuclease activity
GO:0016740transferase activity
GO:0016787hydrolase activity
GO:0042393histone binding
GO:0042803protein homodimerization activity
GO:0043565sequence-specific DNA binding
GO:0061630ubiquitin protein ligase activity
GO:0008270zinc ion binding
GO:0004842ubiquitin-protein transferase activity
GO:0005515protein binding
GO:0046872metal ion binding
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
Vocabulary: biological process
TermDefinition
GO:0006310DNA recombination
GO:0006325chromatin organization
GO:0008152metabolic process
GO:0010390histone monoubiquitination
GO:0030183B cell differentiation
GO:0033077T cell differentiation in thymus
GO:0033151V(D)J recombination
GO:0090305nucleic acid phosphodiester bond hydrolysis
GO:0016567protein ubiquitination
GO:0006955immune response
GO:0007165signal transduction
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000026gut
PLANA:0002032epidermal cell
PLANA:0002142parenchyma
Vocabulary: INTERPRO
TermDefinition
IPR043211TNF_rcpt-assoc_TRAF
IPR013323SIAH-type
IPR013083Znf_RING/FYVE/PHD
IPR008974TRAF-like
IPR001841Znf_RING
IPR002083MATH/TRAF_dom
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 274..294
NoneNo IPR availableCOILSCoilCoilcoord: 196..223
NoneNo IPR availablePANTHERPTHR10131:SF129TNF RECEPTOR-ASSOCIATED FACTOR 6coord: 10..120
coord: 111..406
NoneNo IPR availableCDDcd16449RING-HCcoord: 28..64
e-value: 1.07048E-7
score: 45.9213
NoneNo IPR availableSUPERFAMILYSSF57850RING/U-boxcoord: 25..73
IPR013083Zinc finger, RING/FYVE/PHD-typeGENE3DG3DSA:3.30.40.10coord: 91..147
e-value: 5.3E-6
score: 28.6
IPR013083Zinc finger, RING/FYVE/PHD-typeGENE3DG3DSA:3.30.40.10coord: 19..90
e-value: 1.1E-7
score: 33.5
IPR008974TRAF-likeGENE3DG3DSA:2.60.210.10coord: 255..425
e-value: 2.1E-14
score: 55.5
IPR008974TRAF-likeSUPERFAMILYSSF49599TRAF domain-likecoord: 314..407
IPR008974TRAF-likeSUPERFAMILYSSF49599TRAF domain-likecoord: 95..149
IPR043211TNF receptor-associated factor TRAFPANTHERPTHR10131TNF RECEPTOR ASSOCIATED FACTORcoord: 10..120
coord: 111..406
IPR001841Zinc finger, RING-typePROSITEPS50089ZF_RING_2coord: 28..64
score: 9.214
IPR002083MATH/TRAF domainPROSITEPS50144MATHcoord: 312..456
score: 9.192