Ribonucloprotein

Overview
NameRibonucloprotein
Smed IDSMED30021037
Length (bp)467
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Ribonucloprotein (SMED30021037) t-SNE clustered cells

Violin plots show distribution of expression levels for Ribonucloprotein (SMED30021037) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Ribonucloprotein (SMED30021037) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Ribonucloprotein (SMED30021037) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30021037

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30021037h1SMcG0017252 SmedASXL_007131SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30021037h1SMcG0017252 SmedASXL_007131SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
gutSMED30021037h1SMcG0017252 dd_Smed_v4_1928_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30021037h1SMcG0017252 dd_Smed_v4_1928_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30021037h1SMcG0017252 dd_Smed_v4_1928_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Ribonucloprotein vs. Ensembl Human
Match: SNU13 (small nuclear ribonucleoprotein 13 [Source:HGNC Symbol;Acc:HGNC:7819])

HSP 1 Score: 134.806 bits (338), Expect = 7.542e-41
Identity = 81/128 (63.28%), Postives = 105/128 (82.03%), Query Frame = 3 
Query:   48 MTES-INPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSRHVIACAITESTGSEVTPLVQGIHTAIEKLIV 428
            MTE+ +NPKAYPLA   LT K+++++Q++ +  Q++KGANEATK LNRG ++ IVMAADAEPLEI+LHLPLLCEDKNVPYVF+ SK ALGRACGVSR VIAC++T   GS++   +Q I  +IE+L+V
Sbjct:    1 MTEADVNPKAYPLADAHLTKKLLDLVQQSCNYKQLRKGANEATKTLNRGISEFIVMAADAEPLEIILHLPLLCEDKNVPYVFVRSKQALGRACGVSRPVIACSVTIKEGSQLKQQIQSIQQSIERLLV 128
[Close]
BLAST of Ribonucloprotein vs. Ensembl Human
Match: SNU13 (small nuclear ribonucleoprotein 13 [Source:HGNC Symbol;Acc:HGNC:7819])

HSP 1 Score: 134.806 bits (338), Expect = 7.542e-41
Identity = 81/128 (63.28%), Postives = 105/128 (82.03%), Query Frame = 3 
Query:   48 MTES-INPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSRHVIACAITESTGSEVTPLVQGIHTAIEKLIV 428
            MTE+ +NPKAYPLA   LT K+++++Q++ +  Q++KGANEATK LNRG ++ IVMAADAEPLEI+LHLPLLCEDKNVPYVF+ SK ALGRACGVSR VIAC++T   GS++   +Q I  +IE+L+V
Sbjct:    1 MTEADVNPKAYPLADAHLTKKLLDLVQQSCNYKQLRKGANEATKTLNRGISEFIVMAADAEPLEIILHLPLLCEDKNVPYVFVRSKQALGRACGVSRPVIACSVTIKEGSQLKQQIQSIQQSIERLLV 128
[Close]
BLAST of Ribonucloprotein vs. Ensembl Human
Match: SNU13 (small nuclear ribonucleoprotein 13 [Source:HGNC Symbol;Acc:HGNC:7819])

HSP 1 Score: 134.806 bits (338), Expect = 7.542e-41
Identity = 81/128 (63.28%), Postives = 105/128 (82.03%), Query Frame = 3 
Query:   48 MTES-INPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSRHVIACAITESTGSEVTPLVQGIHTAIEKLIV 428
            MTE+ +NPKAYPLA   LT K+++++Q++ +  Q++KGANEATK LNRG ++ IVMAADAEPLEI+LHLPLLCEDKNVPYVF+ SK ALGRACGVSR VIAC++T   GS++   +Q I  +IE+L+V
Sbjct:    1 MTEADVNPKAYPLADAHLTKKLLDLVQQSCNYKQLRKGANEATKTLNRGISEFIVMAADAEPLEIILHLPLLCEDKNVPYVFVRSKQALGRACGVSRPVIACSVTIKEGSQLKQQIQSIQQSIERLLV 128
[Close]
BLAST of Ribonucloprotein vs. Ensembl Human
Match: SNU13 (small nuclear ribonucleoprotein 13 [Source:HGNC Symbol;Acc:HGNC:7819])

HSP 1 Score: 133.265 bits (334), Expect = 3.516e-40
Identity = 78/124 (62.90%), Postives = 101/124 (81.45%), Query Frame = 3 
Query:   57 SINPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSRHVIACAITESTGSEVTPLVQGIHTAIEKLIV 428
             +NPKAYPLA   LT K+++++Q++ +  Q++KGANEATK LNRG ++ IVMAADAEPLEI+LHLPLLCEDKNVPYVF+ SK ALGRACGVSR VIAC++T   GS++   +Q I  +IE+L+V
Sbjct:    9 DVNPKAYPLADAHLTKKLLDLVQQSCNYKQLRKGANEATKTLNRGISEFIVMAADAEPLEIILHLPLLCEDKNVPYVFVRSKQALGRACGVSRPVIACSVTIKEGSQLKQQIQSIQQSIERLLV 132
[Close]
BLAST of Ribonucloprotein vs. Ensembl Human
Match: SNU13 (small nuclear ribonucleoprotein 13 [Source:HGNC Symbol;Acc:HGNC:7819])

HSP 1 Score: 134.035 bits (336), Expect = 7.376e-39
Identity = 81/128 (63.28%), Postives = 105/128 (82.03%), Query Frame = 3 
Query:   48 MTES-INPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSRHVIACAITESTGSEVTPLVQGIHTAIEKLIV 428
            MTE+ +NPKAYPLA   LT K+++++Q++ +  Q++KGANEATK LNRG ++ IVMAADAEPLEI+LHLPLLCEDKNVPYVF+ SK ALGRACGVSR VIAC++T   GS++   +Q I  +IE+L+V
Sbjct:  145 MTEADVNPKAYPLADAHLTKKLLDLVQQSCNYKQLRKGANEATKTLNRGISEFIVMAADAEPLEIILHLPLLCEDKNVPYVFVRSKQALGRACGVSRPVIACSVTIKEGSQLKQQIQSIQQSIERLLV 272
[Close]
BLAST of Ribonucloprotein vs. Ensembl Celegans
Match: M28.5 (NHP2-like protein 1 homolog [Source:UniProtKB/Swiss-Prot;Acc:Q21568])

HSP 1 Score: 140.584 bits (353), Expect = 1.381e-43
Identity = 77/125 (61.60%), Postives = 103/125 (82.40%), Query Frame = 3 
Query:   54 ESINPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSRHVIACAITESTGSEVTPLVQGIHTAIEKLIV 428
            + +NPKA+PLA   L+ K+++++Q+A +  Q+KKGANEATK LNRG +++IVMAADAEPLEILLHLPLLCEDKNVPYVF+ SK ALGRACGV+R VIA +IT++ GS++   +Q I   +EKL++
Sbjct:    4 DGVNPKAFPLADTNLSQKLMDLVQQAMNYKQLKKGANEATKTLNRGISEIIVMAADAEPLEILLHLPLLCEDKNVPYVFVRSKAALGRACGVTRPVIAASITQNEGSQLKSQIQKIKEDVEKLLI 128
[Close]
BLAST of Ribonucloprotein vs. Ensembl Celegans
Match: Y48A6B.3 (Putative H/ACA ribonucleoprotein complex subunit 2-like protein [Source:UniProtKB/Swiss-Prot;Acc:Q9XXD4])

HSP 1 Score: 61.2326 bits (147), Expect = 2.344e-12
Identity = 37/107 (34.58%), Postives = 63/107 (58.88%), Query Frame = 3 
Query:   48 MTESINPKAYPLAKNELTTKIINVIQKASSLSQ-IKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSRHVIACAITES 365
            + E +NP A PLA  +L  K+  +I+KAS+  + +++G  +  K L R    + ++A +  P+++  H+P +CE+K +PYV+IPS+  LG A G  R  I   +  S
Sbjct:   35 LCELVNPIAQPLANRKLAKKVYKLIKKASAGDKTLREGIKDVQKELRRNEKGICILAGNVSPIDVYSHIPGICEEKEIPYVYIPSREQLGLAVGHRRPSILIFVKPS 141
[Close]
BLAST of Ribonucloprotein vs. Ensembl Fly
Match: hoip (gene:FBgn0286786 transcript:FBtr0079846)

HSP 1 Score: 145.591 bits (366), Expect = 1.550e-45
Identity = 78/127 (61.42%), Postives = 104/127 (81.89%), Query Frame = 3 
Query:   48 MTESINPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSRHVIACAITESTGSEVTPLVQGIHTAIEKLIV 428
            MTE +NPKA+PLA  +LT KI+N++Q+A + +Q++KGANEATK LNRG A ++V+A DAEP+EILLHLPLLCEDKNVPYVF+ SK ALGRACGVSR ++AC++T + GS++   +  I   IE+L+V
Sbjct:    1 MTEEVNPKAFPLADAQLTAKIMNLLQQALNYNQLRKGANEATKTLNRGLADIVVLAGDAEPIEILLHLPLLCEDKNVPYVFVRSKQALGRACGVSRPIVACSVTTNEGSQLKSQITSIQQEIERLLV 127
[Close]
BLAST of Ribonucloprotein vs. Ensembl Fly
Match: hoip (gene:FBgn0286786 transcript:FBtr0335494)

HSP 1 Score: 145.591 bits (366), Expect = 1.550e-45
Identity = 78/127 (61.42%), Postives = 104/127 (81.89%), Query Frame = 3 
Query:   48 MTESINPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSRHVIACAITESTGSEVTPLVQGIHTAIEKLIV 428
            MTE +NPKA+PLA  +LT KI+N++Q+A + +Q++KGANEATK LNRG A ++V+A DAEP+EILLHLPLLCEDKNVPYVF+ SK ALGRACGVSR ++AC++T + GS++   +  I   IE+L+V
Sbjct:    1 MTEEVNPKAFPLADAQLTAKIMNLLQQALNYNQLRKGANEATKTLNRGLADIVVLAGDAEPIEILLHLPLLCEDKNVPYVFVRSKQALGRACGVSRPIVACSVTTNEGSQLKSQITSIQQEIERLLV 127
[Close]
BLAST of Ribonucloprotein vs. Ensembl Fly
Match: NHP2 (gene:FBgn0029148 transcript:FBtr0333076)

HSP 1 Score: 50.0618 bits (118), Expect = 4.707e-8
Identity = 32/103 (31.07%), Postives = 57/103 (55.34%), Query Frame = 3 
Query:   60 INPKAYPLAKNELTTKIINVIQKA-SSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSRHVIACAITES 365
            +N  A P+A  +L  K   +++KA    + ++ G  +    L +G   + + A D  P++I+ HLP +CE+K +PY + PS+  LG A GV R  +A  + ++
Sbjct:   37 VNAIAKPMAGKKLAKKCYKLVKKAMKHKTFLRNGLKDVQTRLRKGETGICIFAGDVTPVDIMCHLPAVCEEKGIPYTYTPSRADLGAAMGVKRGTVALLVRQN 139
[Close]
BLAST of Ribonucloprotein vs. Ensembl Fly
Match: NHP2 (gene:FBgn0029148 transcript:FBtr0075698)

HSP 1 Score: 50.0618 bits (118), Expect = 4.707e-8
Identity = 32/103 (31.07%), Postives = 57/103 (55.34%), Query Frame = 3 
Query:   60 INPKAYPLAKNELTTKIINVIQKA-SSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSRHVIACAITES 365
            +N  A P+A  +L  K   +++KA    + ++ G  +    L +G   + + A D  P++I+ HLP +CE+K +PY + PS+  LG A GV R  +A  + ++
Sbjct:   37 VNAIAKPMAGKKLAKKCYKLVKKAMKHKTFLRNGLKDVQTRLRKGETGICIFAGDVTPVDIMCHLPAVCEEKGIPYTYTPSRADLGAAMGVKRGTVALLVRQN 139
[Close]
BLAST of Ribonucloprotein vs. Ensembl Zebrafish
Match: snu13b (SNU13 homolog, small nuclear ribonucleoprotein b (U4/U6.U5) [Source:ZFIN;Acc:ZDB-GENE-030131-9670])

HSP 1 Score: 145.206 bits (365), Expect = 3.705e-45
Identity = 82/128 (64.06%), Postives = 105/128 (82.03%), Query Frame = 3 
Query:   48 MTES-INPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSRHVIACAITESTGSEVTPLVQGIHTAIEKLIV 428
            MTE+ +NPKAYPLA   L+  I++++Q+AS+  Q++KGANEATK LNRG ++ IVMAADAEPLEI+LHLPLLCEDKNVPYVF+ SK ALGRACGVSR VIA ++T   GS++ P +Q +  AIE+L+V
Sbjct:    1 MTEAEVNPKAYPLADATLSKTILDLVQQASNYKQLRKGANEATKTLNRGISEFIVMAADAEPLEIILHLPLLCEDKNVPYVFVRSKQALGRACGVSRPVIATSVTIKEGSQLKPQIQSVQMAIERLLV 128
[Close]
BLAST of Ribonucloprotein vs. Ensembl Zebrafish
Match: snu13a (SNU13 homolog, small nuclear ribonucleoprotein a (U4/U6.U5) [Source:ZFIN;Acc:ZDB-GENE-040426-879])

HSP 1 Score: 143.28 bits (360), Expect = 2.175e-44
Identity = 81/128 (63.28%), Postives = 104/128 (81.25%), Query Frame = 3 
Query:   48 MTES-INPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSRHVIACAITESTGSEVTPLVQGIHTAIEKLIV 428
            M ES +NPKAYPLA   L+  I++++Q+A++  Q++KGANEATK LNRG ++ IVMAADAEPLEI+LHLPLLCEDKNVPYVF+ SK ALGRACGVSR VIA ++T   GS++ P +Q +  AIE+L+V
Sbjct:    1 MAESDVNPKAYPLADATLSKTILDLVQQAANYKQLRKGANEATKTLNRGISEFIVMAADAEPLEIILHLPLLCEDKNVPYVFVRSKQALGRACGVSRPVIATSVTIKEGSQLKPQIQSVQMAIERLLV 128
[Close]
BLAST of Ribonucloprotein vs. Ensembl Zebrafish
Match: nhp2 (NHP2 ribonucleoprotein homolog (yeast) [Source:NCBI gene;Acc:100003787])

HSP 1 Score: 66.2402 bits (160), Expect = 4.398e-14
Identity = 37/93 (39.78%), Postives = 62/93 (66.67%), Query Frame = 3 
Query:   57 SINPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSR 335
            +INP A PLA  +L+ K+   ++KA+ + QI++G  E  K +N+G   ++V A D  P+++  HLP++CED+++PY ++PSK  LG + G  R
Sbjct:   27 NINPIANPLASRKLSKKLYKCVKKAAKVKQIRRGVKEVQKFINKGETGIVVFAGDTLPIDVYCHLPIMCEDRSLPYAYVPSKVDLGSSAGSKR 119
[Close]
BLAST of Ribonucloprotein vs. Ensembl Xenopus
Match: snu13 (small nuclear ribonucleoprotein 13 [Source:NCBI gene;Acc:394590])

HSP 1 Score: 149.828 bits (377), Expect = 6.525e-47
Identity = 83/128 (64.84%), Postives = 106/128 (82.81%), Query Frame = 3 
Query:   48 MTE-SINPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSRHVIACAITESTGSEVTPLVQGIHTAIEKLIV 428
            MTE  +NPKAYPLA  +LT  +++++Q+A++  Q++KGANEATK LNRG A+ IVMAADAEPLEI+LHLPLLCEDKNVPYVF+ SK ALGRACGVSR VIACA+T   GS++ P +Q +  +IE+L+V
Sbjct:    1 MTEPEVNPKAYPLADAQLTKTLLDLVQQAANYKQLRKGANEATKTLNRGIAEFIVMAADAEPLEIILHLPLLCEDKNVPYVFVRSKQALGRACGVSRPVIACAVTIKEGSQLKPQIQSLQQSIERLLV 128
[Close]
BLAST of Ribonucloprotein vs. Ensembl Xenopus
Match: nhp2 (NHP2 ribonucleoprotein [Source:NCBI gene;Acc:394586])

HSP 1 Score: 71.2478 bits (173), Expect = 8.686e-16
Identity = 38/92 (41.30%), Postives = 59/92 (64.13%), Query Frame = 3 
Query:   60 INPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSR 335
            +NP A PLA  +LT K+   ++KA     I++G  E  K +N+G   ++VMA D  P+E+  H+P++CED+ +PY ++PSK+ LG A G  R
Sbjct:   27 LNPIAKPLAGRKLTKKLYKCVKKAIKQKNIRRGVKEVQKFINKGEKGIVVMAGDTLPIEVYCHIPVMCEDRGIPYSYVPSKSDLGAAAGSKR 118
[Close]
BLAST of Ribonucloprotein vs. Ensembl Mouse
Match: Snu13 (SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5) [Source:MGI Symbol;Acc:MGI:893586])

HSP 1 Score: 134.806 bits (338), Expect = 5.178e-41
Identity = 81/128 (63.28%), Postives = 105/128 (82.03%), Query Frame = 3 
Query:   48 MTES-INPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSRHVIACAITESTGSEVTPLVQGIHTAIEKLIV 428
            MTE+ +NPKAYPLA   LT K+++++Q++ +  Q++KGANEATK LNRG ++ IVMAADAEPLEI+LHLPLLCEDKNVPYVF+ SK ALGRACGVSR VIAC++T   GS++   +Q I  +IE+L+V
Sbjct:    1 MTEADVNPKAYPLADAHLTKKLLDLVQQSCNYKQLRKGANEATKTLNRGISEFIVMAADAEPLEIILHLPLLCEDKNVPYVFVRSKQALGRACGVSRPVIACSVTIKEGSQLKQQIQSIQQSIERLLV 128
[Close]
BLAST of Ribonucloprotein vs. Ensembl Mouse
Match: Nhp2 (NHP2 ribonucleoprotein [Source:MGI Symbol;Acc:MGI:1098547])

HSP 1 Score: 78.5666 bits (192), Expect = 9.737e-19
Identity = 45/93 (48.39%), Postives = 62/93 (66.67%), Query Frame = 3 
Query:   57 SINPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSR 335
            ++NP A PLA   LT K+   I+KA    QI++G  E  K +N+G   ++V+A D  P+E+  HLP+LCED+N+PYV+IPSKT LG A G  R
Sbjct:   30 NLNPIAQPLASRRLTRKLYKCIKKAVKQKQIRRGVKEVQKFVNKGEKGIMVLAGDTLPIEVYCHLPVLCEDQNLPYVYIPSKTDLGAATGSKR 122
[Close]
BLAST of Ribonucloprotein vs. UniProt/SwissProt
Match: sp|Q6P8E9|NH2L1_XENTR (NHP2-like protein 1 OS=Xenopus tropicalis OX=8364 GN=snu13 PE=2 SV=1)

HSP 1 Score: 149.828 bits (377), Expect = 3.456e-46
Identity = 83/128 (64.84%), Postives = 106/128 (82.81%), Query Frame = 3 
Query:   48 MTE-SINPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSRHVIACAITESTGSEVTPLVQGIHTAIEKLIV 428
            MTE  +NPKAYPLA  +LT  +++++Q+A++  Q++KGANEATK LNRG A+ IVMAADAEPLEI+LHLPLLCEDKNVPYVF+ SK ALGRACGVSR VIACA+T   GS++ P +Q +  +IE+L+V
Sbjct:    1 MTEPEVNPKAYPLADAQLTKTLLDLVQQAANYKQLRKGANEATKTLNRGIAEFIVMAADAEPLEIILHLPLLCEDKNVPYVFVRSKQALGRACGVSRPVIACAVTIKEGSQLKPQIQSLQQSIERLLV 128
[Close]
BLAST of Ribonucloprotein vs. UniProt/SwissProt
Match: sp|Q5XH16|NH2L1_XENLA (NHP2-like protein 1 OS=Xenopus laevis OX=8355 GN=snu13 PE=2 SV=1)

HSP 1 Score: 149.058 bits (375), Expect = 8.849e-46
Identity = 82/128 (64.06%), Postives = 106/128 (82.81%), Query Frame = 3 
Query:   48 MTE-SINPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSRHVIACAITESTGSEVTPLVQGIHTAIEKLIV 428
            MTE  +NPKAYPLA  +LT  +++++Q++++  Q++KGANEATK LNRG A+ IVMAADAEPLEI+LHLPLLCEDKNVPYVF+ SK ALGRACGVSR VIAC++T   GS++ P +Q +  AIE+L+V
Sbjct:    1 MTEPEVNPKAYPLADAQLTKTLLDLVQQSANYKQLRKGANEATKTLNRGIAEFIVMAADAEPLEIILHLPLLCEDKNVPYVFVRSKQALGRACGVSRPVIACSVTIKEGSQLKPQIQSVQQAIERLLV 128
[Close]
BLAST of Ribonucloprotein vs. UniProt/SwissProt
Match: sp|O74690|SNU13_SCHPO (13 kDa ribonucleoprotein-associated protein OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=snu13 PE=3 SV=1)

HSP 1 Score: 146.747 bits (369), Expect = 6.365e-45
Identity = 80/124 (64.52%), Postives = 103/124 (83.06%), Query Frame = 3 
Query:   57 SINPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSRHVIACAITESTGSEVTPLVQGIHTAIEKLIV 428
            S+NPKA+PLA + LT +I++++Q+AS   Q++KGANEATK LNRG ++ IVMAAD EP+EILLHLPLLCEDKNVPYVF+PSK ALGRACGVSR VI+ +IT +  S++ P +Q I  AIEKL++
Sbjct:    2 SVNPKAFPLADSGLTQQILDLVQQASHYKQLRKGANEATKTLNRGISEFIVMAADTEPIEILLHLPLLCEDKNVPYVFVPSKAALGRACGVSRPVISASITTNEASDLLPQIQAIKLAIEKLLI 125
[Close]
BLAST of Ribonucloprotein vs. UniProt/SwissProt
Match: sp|Q9U3Z7|NH2L1_DROME (NHP2-like protein 1 homolog OS=Drosophila melanogaster OX=7227 GN=hoip PE=2 SV=1)

HSP 1 Score: 145.591 bits (366), Expect = 1.553e-44
Identity = 78/127 (61.42%), Postives = 104/127 (81.89%), Query Frame = 3 
Query:   48 MTESINPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSRHVIACAITESTGSEVTPLVQGIHTAIEKLIV 428
            MTE +NPKA+PLA  +LT KI+N++Q+A + +Q++KGANEATK LNRG A ++V+A DAEP+EILLHLPLLCEDKNVPYVF+ SK ALGRACGVSR ++AC++T + GS++   +  I   IE+L+V
Sbjct:    1 MTEEVNPKAFPLADAQLTAKIMNLLQQALNYNQLRKGANEATKTLNRGLADIVVLAGDAEPIEILLHLPLLCEDKNVPYVFVRSKQALGRACGVSRPIVACSVTTNEGSQLKSQITSIQQEIERLLV 127
[Close]
BLAST of Ribonucloprotein vs. UniProt/SwissProt
Match: sp|Q21568|NH2L1_CAEEL (NHP2-like protein 1 homolog OS=Caenorhabditis elegans OX=6239 GN=M28.5 PE=3 SV=1)

HSP 1 Score: 140.584 bits (353), Expect = 1.757e-42
Identity = 77/125 (61.60%), Postives = 103/125 (82.40%), Query Frame = 3 
Query:   54 ESINPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSRHVIACAITESTGSEVTPLVQGIHTAIEKLIV 428
            + +NPKA+PLA   L+ K+++++Q+A +  Q+KKGANEATK LNRG +++IVMAADAEPLEILLHLPLLCEDKNVPYVF+ SK ALGRACGV+R VIA +IT++ GS++   +Q I   +EKL++
Sbjct:    4 DGVNPKAFPLADTNLSQKLMDLVQQAMNYKQLKKGANEATKTLNRGISEIIVMAADAEPLEILLHLPLLCEDKNVPYVFVRSKAALGRACGVTRPVIAASITQNEGSQLKSQIQKIKEDVEKLLI 128
[Close]
BLAST of Ribonucloprotein vs. TrEMBL
Match: A0A0K8RLH7 (Ribonucloprotein OS=Ixodes ricinus OX=34613 PE=2 SV=1)

HSP 1 Score: 165.622 bits (418), Expect = 7.087e-50
Identity = 90/127 (70.87%), Postives = 109/127 (85.83%), Query Frame = 3 
Query:   48 MTESINPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSRHVIACAITESTGSEVTPLVQGIHTAIEKLIV 428
            M + +NPKAYPLA  ELTTKI+NV+Q+A++  Q+KKGANEATKALNRG A++IVMAADA PLEILLHLPLLCEDKNVPYVF+ SK ALGRACGVSR VIAC++T + GS++ P +QG+   IEKL+V
Sbjct:    1 MADEVNPKAYPLADPELTTKILNVVQQATNYKQMKKGANEATKALNRGLAEIIVMAADATPLEILLHLPLLCEDKNVPYVFVRSKHALGRACGVSRPVIACSVTVNEGSQLKPQIQGLQQEIEKLLV 127
[Close]
BLAST of Ribonucloprotein vs. TrEMBL
Match: A0A2R5L6F5 (Ribonucloprotein OS=Ornithodoros turicata OX=34597 PE=3 SV=1)

HSP 1 Score: 164.851 bits (416), Expect = 1.412e-49
Identity = 89/127 (70.08%), Postives = 108/127 (85.04%), Query Frame = 3 
Query:   48 MTESINPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSRHVIACAITESTGSEVTPLVQGIHTAIEKLIV 428
            M E +NPKAYPLA  ELTTKI+N++Q+A++  Q++KGANEATKALNRG A+ IVMAADA PLEILLHLPLLCEDKNVPYVFI SK ALGRACGV+R VIAC++T + GS++ P +QG+   IEKL+V
Sbjct:    1 MAEEVNPKAYPLADPELTTKILNIVQQATNYKQMRKGANEATKALNRGLAEFIVMAADATPLEILLHLPLLCEDKNVPYVFIRSKHALGRACGVTRPVIACSVTVNEGSQLKPQIQGLQQEIEKLLV 127
[Close]
BLAST of Ribonucloprotein vs. TrEMBL
Match: A0A293MU43 (Ribonucloprotein (Fragment) OS=Ornithodoros erraticus OX=265619 PE=3 SV=1)

HSP 1 Score: 164.081 bits (414), Expect = 2.606e-49
Identity = 89/127 (70.08%), Postives = 107/127 (84.25%), Query Frame = 3 
Query:   48 MTESINPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSRHVIACAITESTGSEVTPLVQGIHTAIEKLIV 428
            M E +NPKAYPLA  ELTTKI+N++Q+A++  Q++KGANEATKALNRG A+ IVMAADA PLEILLHLPLLCEDKNVPYVFI SK ALGRACGVSR VIAC++  + GS++ P +QG+   IEKL+V
Sbjct:    1 MAEEVNPKAYPLADPELTTKILNIVQQATNYKQMRKGANEATKALNRGLAEFIVMAADAVPLEILLHLPLLCEDKNVPYVFIRSKHALGRACGVSRPVIACSVMVNEGSQLKPQIQGLQQEIEKLLV 127
[Close]
BLAST of Ribonucloprotein vs. TrEMBL
Match: A0A1S8WWT8 (Ribonucloprotein OS=Opisthorchis viverrini OX=6198 GN=X801_05204 PE=3 SV=1)

HSP 1 Score: 162.925 bits (411), Expect = 8.277e-49
Identity = 89/128 (69.53%), Postives = 109/128 (85.16%), Query Frame = 3 
Query:   45 KMTESINPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSRHVIACAITESTGSEVTPLVQGIHTAIEKLIV 428
            ++TE INP+AYPLA  ELT K+I ++++ASS  Q+KKGANEATKALNRG+A+ IVMAAD EPLEI+LHLPLLCEDKNVPYVFIPS+ ALGRACGVSR V A A+T+S GS++ PLV  I  +IEKL++
Sbjct:    3 QVTEGINPRAYPLAGPELTNKLIELVKQASSYKQLKKGANEATKALNRGKAEFIVMAADIEPLEIVLHLPLLCEDKNVPYVFIPSQMALGRACGVSRSVAAVAVTDSEGSQLKPLVTAIQQSIEKLLI 130
[Close]
BLAST of Ribonucloprotein vs. TrEMBL
Match: A0A0X3PUI6 (Ribonucloprotein (Fragment) OS=Schistocephalus solidus OX=70667 GN=NH2L1 PE=3 SV=1)

HSP 1 Score: 163.31 bits (412), Expect = 8.298e-49
Identity = 88/127 (69.29%), Postives = 107/127 (84.25%), Query Frame = 3 
Query:   48 MTESINPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSRHVIACAITESTGSEVTPLVQGIHTAIEKLIV 428
            M E +NPKAYPLA  ELTTKII ++++A+S  Q+KKGANEATKALNRG+A+ IVMAAD  P+EI+LHLPLLCEDKNVPYVFI S+ ALGRACGVSR VIA A+T+S GS++ PLV  I  +IEKL++
Sbjct:   18 MAEEVNPKAYPLASPELTTKIIELVKQAASYKQLKKGANEATKALNRGKAEFIVMAADTNPIEIVLHLPLLCEDKNVPYVFISSQQALGRACGVSRPVIAVAVTDSEGSQLKPLVTNIQLSIEKLLI 144
[Close]
BLAST of Ribonucloprotein vs. Ensembl Cavefish
Match: snu13a (NHP2-like protein 1 [Source:NCBI gene;Acc:103040872])

HSP 1 Score: 142.895 bits (359), Expect = 2.422e-44
Identity = 79/123 (64.23%), Postives = 101/123 (82.11%), Query Frame = 3 
Query:   60 INPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSRHVIACAITESTGSEVTPLVQGIHTAIEKLIV 428
            +NPKAYPLA   LT  I++++Q+A++  Q++KGANEATK LNRG ++ IVMAADAEPLEI+LHLPLLCEDKNVPYVF+ SK ALGRACGVSR VIA ++T   GS++ P +Q +  AIE+L+V
Sbjct:    6 VNPKAYPLADATLTKTILDLVQQAANYKQLRKGANEATKTLNRGISEFIVMAADAEPLEIILHLPLLCEDKNVPYVFVRSKQALGRACGVSRPVIATSVTIKEGSQLKPQIQSVQMAIERLLV 128
[Close]
BLAST of Ribonucloprotein vs. Ensembl Cavefish
Match: snu13b (small nuclear ribonucleoprotein 13 [Source:NCBI gene;Acc:103032763])

HSP 1 Score: 142.124 bits (357), Expect = 4.417e-44
Identity = 79/128 (61.72%), Postives = 105/128 (82.03%), Query Frame = 3 
Query:   48 MTES-INPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSRHVIACAITESTGSEVTPLVQGIHTAIEKLIV 428
            M+E+ +NPKAYPLA   L+  I++++Q+AS+  Q++KGANE+TK LNRG ++ IVMAADAEPLEI+LHLPLLCEDKNVPYVF+ SK ALGRACGVSR +IA ++T   GS++ P +Q +  AIE+L+V
Sbjct:    1 MSETEVNPKAYPLADATLSKTILDLVQQASNYKQLRKGANESTKTLNRGISEFIVMAADAEPLEIILHLPLLCEDKNVPYVFVRSKQALGRACGVSRPIIATSVTIKEGSQLKPQIQSVQMAIERLLV 128
[Close]
BLAST of Ribonucloprotein vs. Ensembl Cavefish
Match: snu13b (small nuclear ribonucleoprotein 13 [Source:NCBI gene;Acc:103032763])

HSP 1 Score: 141.739 bits (356), Expect = 9.101e-44
Identity = 77/123 (62.60%), Postives = 101/123 (82.11%), Query Frame = 3 
Query:   60 INPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSRHVIACAITESTGSEVTPLVQGIHTAIEKLIV 428
            +NPKAYPLA   L+  I++++Q+AS+  Q++KGANE+TK LNRG ++ IVMAADAEPLEI+LHLPLLCEDKNVPYVF+ SK ALGRACGVSR +IA ++T   GS++ P +Q +  AIE+L+V
Sbjct:   15 VNPKAYPLADATLSKTILDLVQQASNYKQLRKGANESTKTLNRGISEFIVMAADAEPLEIILHLPLLCEDKNVPYVFVRSKQALGRACGVSRPIIATSVTIKEGSQLKPQIQSVQMAIERLLV 137
[Close]
BLAST of Ribonucloprotein vs. Ensembl Cavefish
Match: nhp2 (NHP2 ribonucleoprotein [Source:NCBI gene;Acc:103032164])

HSP 1 Score: 77.7962 bits (190), Expect = 1.357e-18
Identity = 40/93 (43.01%), Postives = 63/93 (67.74%), Query Frame = 3 
Query:   57 SINPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSR 335
            +INP A PLA  +L+ K+   ++KA+ L QI++G  E  K +N+G   ++V+A D  P+++  HLP++CED+N+PY +IPSK  LG + G  R
Sbjct:   28 NINPIANPLASRKLSKKLYKCVKKAAKLKQIRRGVKEVQKFINKGETGIVVLAGDTLPIDVYCHLPVMCEDRNLPYAYIPSKVDLGSSAGSKR 120
[Close]
BLAST of Ribonucloprotein vs. Ensembl Sea Lamprey
Match: nhp2 (NHP2 ribonucleoprotein homolog (yeast) [Source:NCBI gene;Acc:100003787])

HSP 1 Score: 59.6918 bits (143), Expect = 2.194e-12
Identity = 34/88 (38.64%), Postives = 56/88 (63.64%), Query Frame = 3 
Query:   72 AYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSR 335
            A PLA  +LT ++   I+KAS    +++G  E  K L +G   ++V+A D +P+E++ H+P++CED+N+PY +   K+ LG A G  R
Sbjct:   37 ANPLASRKLTKRLYKTIKKASKQKMLRRGVKEVQKFLKKGEKGIVVLAGDTQPVEVICHIPIMCEDQNLPYCYEGGKSDLGGAAGSKR 124
[Close]
BLAST of Ribonucloprotein vs. Ensembl Yeast
Match: SNU13 (RNA binding protein; part of U3 snoRNP involved in rRNA processing, part of U4/U6-U5 tri-snRNP involved in mRNA splicing, similar to human 15.5K protein [Source:SGD;Acc:S000000752])

HSP 1 Score: 134.035 bits (336), Expect = 8.661e-42
Identity = 75/122 (61.48%), Postives = 97/122 (79.51%), Query Frame = 3 
Query:   63 NPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSRHVIACAITESTGSEVTPLVQGIHTAIEKLIV 428
            NPKA+PLA   LT +I++V+Q+A++L Q+KKGANEATK LNRG ++ I+MAAD EP+EILLHLPLLCEDKNVPYVF+PS+ ALGRACGVSR VIA +IT +  S +   +  +   IE L++
Sbjct:    5 NPKAFPLADAALTQQILDVVQQAANLRQLKKGANEATKTLNRGISEFIIMAADCEPIEILLHLPLLCEDKNVPYVFVPSRVALGRACGVSRPVIAASITTNDASAIKTQIYAVKDKIETLLI 126
[Close]
BLAST of Ribonucloprotein vs. Ensembl Yeast
Match: NHP2 (Protein related to mammalian high mobility group (HMG) proteins; nuclear protein; essential for function of H/ACA-type snoRNPs, which are involved in 18S rRNA processing [Source:SGD;Acc:S000002367])

HSP 1 Score: 72.4034 bits (176), Expect = 2.203e-17
Identity = 40/90 (44.44%), Postives = 57/90 (63.33%), Query Frame = 3 
Query:   66 PKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSR 335
            P A PLA  +L  K++  ++KAS    +K+G  E  KAL +G   L+V+A D  P +++ H+P+LCED +VPY+FIPSK  LG A    R
Sbjct:   29 PFAKPLASKKLNKKVLKTVKKASKAKNVKRGVKEVVKALRKGEKGLVVIAGDISPADVISHIPVLCEDHSVPYIFIPSKQDLGAAGATKR 118
[Close]
BLAST of Ribonucloprotein vs. Ensembl Nematostella
Match: EDO36839 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHG4])

HSP 1 Score: 145.976 bits (367), Expect = 4.731e-46
Identity = 81/126 (64.29%), Postives = 104/126 (82.54%), Query Frame = 3 
Query:   51 TESINPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSRHVIACAITESTGSEVTPLVQGIHTAIEKLIV 428
            +E +NPKA+PLA  +LT  I+++IQ+A++  Q++KGANEATK LNRG A+ IVMAAD EPLEILLHLPLLCEDKNVPYVF+ SK ALGRA GV+R VIACA+T + GS++ P +Q +  AIEKL++
Sbjct:    3 SEEVNPKAFPLADPQLTVTILDLIQQATNYKQLRKGANEATKCLNRGIAEFIVMAADTEPLEILLHLPLLCEDKNVPYVFVRSKAALGRATGVTRPVIACAVTVNEGSQLKPQIQTLQNAIEKLLI 128
[Close]
BLAST of Ribonucloprotein vs. Ensembl Nematostella
Match: EDO48688 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RID9])

HSP 1 Score: 63.929 bits (154), Expect = 1.067e-13
Identity = 31/81 (38.27%), Postives = 52/81 (64.20%), Query Frame = 3 
Query:   72 AYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALG 314
            A PLA  +LT K+   ++KAS    +++G  E  KAL +G    +++A D  P++++ H+P++CED  +PY ++PSK  LG
Sbjct:   34 AKPLASRKLTKKLYKTVKKASKAKTLRRGVKEVVKALRKGEKGFVILAGDVSPIDVISHIPVMCEDSKIPYAYVPSKVDLG 114
[Close]
BLAST of Ribonucloprotein vs. Ensembl Medaka
Match: snu13a (small nuclear ribonucleoprotein 13 [Source:NCBI gene;Acc:101175271])

HSP 1 Score: 145.591 bits (366), Expect = 2.060e-45
Identity = 83/128 (64.84%), Postives = 104/128 (81.25%), Query Frame = 3 
Query:   48 MTE-SINPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSRHVIACAITESTGSEVTPLVQGIHTAIEKLIV 428
            M+E  +NPKAYPLA   LT  I++++Q+AS+  Q++KGANEATK LNRG A+ IVMAADAEPLEI+LHLPLLCEDKNVPYVF+ SK ALGRACGVSR VIA ++T   GS++ P +Q +  AIE+L+V
Sbjct:    1 MSEPEVNPKAYPLADATLTKTILDLVQQASNYKQLRKGANEATKTLNRGIAEFIVMAADAEPLEIILHLPLLCEDKNVPYVFVRSKQALGRACGVSRPVIATSVTIKEGSQLKPQIQSVQMAIERLLV 128
[Close]
BLAST of Ribonucloprotein vs. Ensembl Medaka
Match: nhp2 (NHP2 ribonucleoprotein [Source:NCBI gene;Acc:101168479])

HSP 1 Score: 73.559 bits (179), Expect = 6.514e-17
Identity = 39/100 (39.00%), Postives = 65/100 (65.00%), Query Frame = 3 
Query:   36 SRFKMTESINPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSR 335
            S  ++  ++NP A PLA  +L+ K+   ++KA+ +  I++G  E  K +N+G   ++V+A D  P+E+  HLP++CED+++PY +IPSK  LG A G  R
Sbjct:   21 SYHELIANLNPIAQPLASRKLSKKLYKCVKKAARVKNIRRGVKEVQKFINKGEKGIVVLAGDTLPIEVYCHLPVMCEDRSLPYAYIPSKVDLGSAAGSKR 120
[Close]
BLAST of Ribonucloprotein vs. Ensembl Medaka
Match: nhp2 (NHP2 ribonucleoprotein [Source:NCBI gene;Acc:101168479])

HSP 1 Score: 65.855 bits (159), Expect = 4.726e-14
Identity = 34/90 (37.78%), Postives = 60/90 (66.67%), Query Frame = 3 
Query:   36 SRFKMTESINPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKT 305
            S  ++  ++NP A PLA  +L+ K+   ++KA+ +  I++G  E  K +N+G   ++V+A D  P+E+  HLP++CED+++PY +IPSK 
Sbjct:   21 SYHELIANLNPIAQPLASRKLSKKLYKCVKKAARVKNIRRGVKEVQKFINKGEKGIVVLAGDTLPIEVYCHLPVMCEDRSLPYAYIPSKV 110
[Close]
BLAST of Ribonucloprotein vs. Planmine SMEST
Match: SMESG000027962.1 (SMESG000027962.1)

HSP 1 Score: 228.024 bits (580), Expect = 3.715e-78
Identity = 127/127 (100.00%), Postives = 127/127 (100.00%), Query Frame = 3 
Query:   48 MTESINPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSRHVIACAITESTGSEVTPLVQGIHTAIEKLIV 428
            MTESINPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAEPLEILLHLPLLCEDKNVPYVFIPSKTALGRACGVSRHVIACAITESTGSEVTPLVQGIHTAIEKLIV
Sbjct:    1 MTESINPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAEPLEILLHLPLLCEDKNVPYVFIPSKTALGRACGVSRHVIACAITESTGSEVTPLVQGIHTAIEKLIV 127
[Close]
BLAST of Ribonucloprotein vs. Planmine SMEST
Match: SMESG000069457.1 (SMESG000069457.1)

HSP 1 Score: 45.8246 bits (107), Expect = 8.999e-7
Identity = 28/80 (35.00%), Postives = 43/80 (53.75%), Query Frame = 3 
Query:   96 LTTKIINVIQKASSLSQIKKGANEATKALNRGRAQLIVMAADAXXXXXXXXXXXXCEDKNVPYVFIPSKTALGRACGVSR 335
            L + + +V  +A +L+ + +G  E  K+L R  A L V A D E   I+  +  LC + NVP++  PSK  LG   G+ R
Sbjct:    3 LDSALSDVFHRAFALNILCRGLKECVKSLERQTAVLCVGADDTEERAIISLIQSLCVNNNVPFIHFPSKYRLGEISGLRR 82
The following BLAST results are available for this feature:
BLAST of Ribonucloprotein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SNU137.542e-4163.28small nuclear ribonucleoprotein 13 [Source:HGNC Sy... [more]
SNU137.542e-4163.28small nuclear ribonucleoprotein 13 [Source:HGNC Sy... [more]
SNU137.542e-4163.28small nuclear ribonucleoprotein 13 [Source:HGNC Sy... [more]
SNU133.516e-4062.90small nuclear ribonucleoprotein 13 [Source:HGNC Sy... [more]
SNU137.376e-3963.28small nuclear ribonucleoprotein 13 [Source:HGNC Sy... [more]
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BLAST of Ribonucloprotein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
M28.51.381e-4361.60NHP2-like protein 1 homolog [Source:UniProtKB/Swi... [more]
Y48A6B.32.344e-1234.58Putative H/ACA ribonucleoprotein complex subunit 2... [more]
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BLAST of Ribonucloprotein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4
Match NameE-valueIdentityDescription
hoip1.550e-4561.42gene:FBgn0286786 transcript:FBtr0079846[more]
hoip1.550e-4561.42gene:FBgn0286786 transcript:FBtr0335494[more]
NHP24.707e-831.07gene:FBgn0029148 transcript:FBtr0333076[more]
NHP24.707e-831.07gene:FBgn0029148 transcript:FBtr0075698[more]
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BLAST of Ribonucloprotein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
snu13b3.705e-4564.06SNU13 homolog, small nuclear ribonucleoprotein b (... [more]
snu13a2.175e-4463.28SNU13 homolog, small nuclear ribonucleoprotein a (... [more]
nhp24.398e-1439.78NHP2 ribonucleoprotein homolog (yeast) [Source:NCB... [more]
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BLAST of Ribonucloprotein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2
Match NameE-valueIdentityDescription
snu136.525e-4764.84small nuclear ribonucleoprotein 13 [Source:NCBI ge... [more]
nhp28.686e-1641.30NHP2 ribonucleoprotein [Source:NCBI gene;Acc:39458... [more]
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BLAST of Ribonucloprotein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Snu135.178e-4163.28SNU13 homolog, small nuclear ribonucleoprotein (U4... [more]
Nhp29.737e-1948.39NHP2 ribonucleoprotein [Source:MGI Symbol;Acc:MGI:... [more]
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BLAST of Ribonucloprotein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q6P8E9|NH2L1_XENTR3.456e-4664.84NHP2-like protein 1 OS=Xenopus tropicalis OX=8364 ... [more]
sp|Q5XH16|NH2L1_XENLA8.849e-4664.06NHP2-like protein 1 OS=Xenopus laevis OX=8355 GN=s... [more]
sp|O74690|SNU13_SCHPO6.365e-4564.5213 kDa ribonucleoprotein-associated protein OS=Sch... [more]
sp|Q9U3Z7|NH2L1_DROME1.553e-4461.42NHP2-like protein 1 homolog OS=Drosophila melanoga... [more]
sp|Q21568|NH2L1_CAEEL1.757e-4261.60NHP2-like protein 1 homolog OS=Caenorhabditis eleg... [more]
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BLAST of Ribonucloprotein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0K8RLH77.087e-5070.87Ribonucloprotein OS=Ixodes ricinus OX=34613 PE=2 S... [more]
A0A2R5L6F51.412e-4970.08Ribonucloprotein OS=Ornithodoros turicata OX=34597... [more]
A0A293MU432.606e-4970.08Ribonucloprotein (Fragment) OS=Ornithodoros errati... [more]
A0A1S8WWT88.277e-4969.53Ribonucloprotein OS=Opisthorchis viverrini OX=6198... [more]
A0A0X3PUI68.298e-4969.29Ribonucloprotein (Fragment) OS=Schistocephalus sol... [more]
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BLAST of Ribonucloprotein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
snu13a2.422e-4464.23NHP2-like protein 1 [Source:NCBI gene;Acc:10304087... [more]
snu13b4.417e-4461.72small nuclear ribonucleoprotein 13 [Source:NCBI ge... [more]
snu13b9.101e-4462.60small nuclear ribonucleoprotein 13 [Source:NCBI ge... [more]
nhp21.357e-1843.01NHP2 ribonucleoprotein [Source:NCBI gene;Acc:10303... [more]
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BLAST of Ribonucloprotein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
nhp22.194e-1238.64NHP2 ribonucleoprotein homolog (yeast) [Source:NCB... [more]
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BLAST of Ribonucloprotein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2
Match NameE-valueIdentityDescription
SNU138.661e-4261.48RNA binding protein; part of U3 snoRNP involved in... [more]
NHP22.203e-1744.44Protein related to mammalian high mobility group (... [more]
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BLAST of Ribonucloprotein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO368394.731e-4664.29Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO486881.067e-1338.27Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Ribonucloprotein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
snu13a2.060e-4564.84small nuclear ribonucleoprotein 13 [Source:NCBI ge... [more]
nhp26.514e-1739.00NHP2 ribonucleoprotein [Source:NCBI gene;Acc:10116... [more]
nhp24.726e-1437.78NHP2 ribonucleoprotein [Source:NCBI gene;Acc:10116... [more]
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BLAST of Ribonucloprotein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000027962.13.715e-78100.00SMESG000027962.1[more]
SMESG000069457.18.999e-735.00SMESG000069457.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30021037 ID=SMED30021037|Name=Ribonucloprotein|organism=Schmidtea mediterranea sexual|type=transcript|length=467bp
ATATTGTTTTAATTCTTTGCAATTTTTAAATATTATCAAGATTTAAAATG
ACTGAATCAATCAATCCTAAAGCTTACCCCTTAGCTAAAAACGAGCTCAC
TACTAAAATTATCAACGTTATTCAAAAAGCGTCTAGTTTAAGTCAAATAA
AGAAAGGAGCAAATGAAGCTACAAAAGCCTTGAATCGTGGAAGAGCACAA
TTAATAGTTATGGCAGCTGATGCTGAACCTTTGGAAATCTTGCTCCACTT
GCCCTTGTTATGCGAAGATAAGAATGTTCCATACGTTTTTATTCCTAGTA
AGACTGCTCTTGGTAGAGCATGTGGAGTTTCTCGACATGTTATCGCTTGT
GCTATTACAGAAAGTACAGGATCAGAAGTAACTCCATTAGTTCAAGGAAT
TCACACTGCTATCGAGAAACTTATTGTATAAATAAATATGTGTCTAATGA
AAAAAAAAGATCGGAAG
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protein sequence of SMED30021037-orf-1

>SMED30021037-orf-1 ID=SMED30021037-orf-1|Name=SMED30021037-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=128bp
MTESINPKAYPLAKNELTTKIINVIQKASSLSQIKKGANEATKALNRGRA
QLIVMAADAEPLEILLHLPLLCEDKNVPYVFIPSKTALGRACGVSRHVIA
CAITESTGSEVTPLVQGIHTAIEKLIV*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
GO:1990904ribonucleoprotein complex
GO:0005730nucleolus
GO:0030529intracellular ribonucleoprotein complex
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000429neoblast
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR002415H/ACA_rnp_Nhp2_euk
IPR018492Ribosomal_L7Ae/L8/Nhp2
IPR004038Ribosomal_L7Ae/L30e/S12e/Gad45
IPR029064L30e-like
IPR004037Ribosomal_L7Ae_CS
Vocabulary: molecular function
TermDefinition
GO:0003723RNA binding
Vocabulary: biological process
TermDefinition
GO:0042254ribosome biogenesis
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR018492Ribosomal protein L7Ae/L8/Nhp2 familyPRINTSPR00881L7ARS6FAMILYcoord: 69..79
score: 66.53
coord: 79..93
score: 47.88
coord: 34..48
score: 46.67
coord: 53..66
score: 44.48
IPR002415H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryotePRINTSPR00883NUCLEARHMGcoord: 20..35
score: 31.25
coord: 81..93
score: 75.38
coord: 37..47
score: 81.82
coord: 7..20
score: 58.57
IPR004038Ribosomal protein L7Ae/L30e/S12e/Gadd45PFAMPF01248Ribosomal_L7Aecoord: 20..110
e-value: 2.4E-27
score: 94.5
IPR02906450S ribosomal protein L30e-likeGENE3DG3DSA:3.30.1330.30coord: 1..127
e-value: 2.8E-47
score: 161.5
IPR02906450S ribosomal protein L30e-likeSUPERFAMILYSSF55315L30e-likecoord: 5..125
NoneNo IPR availablePANTHERPTHR23105RIBOSOMAL PROTEIN L7AE FAMILY MEMBERcoord: 2..127
NoneNo IPR availablePANTHERPTHR23105:SF117coord: 2..127
IPR004037Ribosomal protein L7Ae conserved sitePROSITEPS01082RIBOSOMAL_L7AEcoord: 72..89