Frizzled-5

Overview


Name	Frizzled-5
Smed ID	SMED30020953
Length (bp)	1862

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Frizzled-5 (SMED30020953) t-SNE clustered cells

Violin plots show distribution of expression levels for Frizzled-5 (SMED30020953) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Frizzled-5 (SMED30020953) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Frizzled-5 (SMED30020953) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30020953

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
head region	SMED30020953	SMESG000031852.1	SmedASXL_007427	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
nervous system	SMED30020953	SMESG000031852.1	dd_Smed_v4_19866_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30020953	SMESG000031852.1	dd_Smed_v6_19866_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
photoreceptor neuron	SMED30020953	SMESG000031852.1	SMED30020953	smed_20140614	PMID:22884275 Lapan et al., 2012
head region	SMED30020953	SMESG000031852.1	OX_Smed_1.0.10050	ox_Smed_v2	PMID:24238224 Kao et al., 2013
head region	SMED30020953	SMESG000031852.1	OX_Smed_1.0.07568	ox_Smed_v2	PMID:24238224 Kao et al., 2013

Note: Hover over icons to view figure legend

Homology

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BLAST of Frizzled-5 vs. Ensembl Human
Match: FZD5 (frizzled class receptor 5 [Source:HGNC Symbol;Acc:HGNC:4043])

HSP 1 Score: 503.056 bits (1294), Expect = 7.552e-172
Identity = 271/537 (50.47%), Postives = 356/537 (66.29%), Query Frame = 2

Query:   80 RICGQSFSISKPDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLP---EDNACLRKDNKTRSNKTTNFVSERPYLLK------------SKKCH------CHCRSPLII---DSRDHFNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVAC--KSDAIRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPC-----RTKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLCCRKSLHHK 1597
            ++ G++ + SK  +    C  I + MC+GIGYNLT++PN  NH + +EAGLE+ QF  LVEI CS DLR FLCSMY PICLP++   +P CRS+C  A+ GC+ +M QYGF WPE M+C++LP    D   L  D   RS  TT     RP+  K              +C       C CR P +    +S   +NKV TG + NC + C  P F   +++F+TFW+G+W+ +C ISTS T+ TF ID  RF+YPERPIIFLS CYL +S+G+L+R+ +GH +VAC  + + I Y ++G   C+IVFL +YFFGMASSIWWV+L+ TWFLAAG+KWG+EAI  YA  +H  AW IP ++SI  L +SSVDGDPV+GICYVGN N  +L  FV+ PL++YLLVGT FLLAGF++L +IR  IK+ G +KTDKLEKLMIRI IF ++Y+VP   VV C +YE  +R+ WE + TC C        + +PEY V MLKYFM LVVG T+G WIW+ KT++SW + F    CCR    HK
Sbjct:   19 QLVGRAAAASKAPV----CQEITVPMCRGIGYNLTHMPNQFNHDTQDEAGLEVHQFWPLVEIQCSPDLRFFLCSMYTPICLPDYHKPLPPCRSVCERAKAGCSPLMRQYGFAWPERMSCDRLPVLGRDAEVLCMDYN-RSEATT--APPRPFPAKPTLPGPPGAPASGGECPAGGPFVCKCREPFVPILKESHPLYNKVRTGQVPNCAVPCYQPSFSADERTFATFWIGLWSVLCFISTSTTVATFLIDMERFRYPERPIIFLSACYLCVSLGFLVRLVVGHASVACSREHNHIHYETTGPALCTIVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYAQYFHLAAWLIPSVKSITALALSSVDGDPVAGICYVGNQNLNSLRGFVLGPLVLYLLVGTLFLLAGFVSLFRIRSVIKQGG-TKTDKLEKLMIRIGIFTLLYTVPASIVVACYLYEQHYRESWEAALTCACPGHDTGQPRAKPEYWVLMLKYFMCLVVGITSGVWIWSGKTVESWRR-FTSRCCCRPRRGHK 546

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BLAST of Frizzled-5 vs. Ensembl Human
Match: FZD10 (frizzled class receptor 10 [Source:HGNC Symbol;Acc:HGNC:4039])

HSP 1 Score: 409.453 bits (1051), Expect = 2.073e-135
Identity = 232/531 (43.69%), Postives = 320/531 (60.26%), Query Frame = 2

Query:   68 WVLFRICGQSFSISKPDL-RPST--CIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNA----CLRKDNKTRSNKTTNFVSERPYLLKSKKCHCHCRSPLI--------IDSRDHFNKVVTGNISNCLMNCRSP---YFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDA-----IRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWE------------QSYTCPCRTKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKV 1555
            W++ ++ G   +IS  D+ RP    C PIEI MCK IGYN+T +PN + H +  EA +++ +F  LVE  C   LR FLCS+YAP+C       IPACR +C  AR  C+ +M Q+ FKWP+ ++C KLP  N     C+   N   S++ T      P L + ++ H     PL          D+   F+ V     ++C   C      Y+   DK F+  WL IWA +C  S++ T+LTF ID +RF+YPERPIIFLS+CY + SVGYLIR+  G E++AC  D+     I+ G   +  C++VFL +Y+FGMASS+WWVVLT TWFLAAG KWG EAI   +  +H  AW IP +++I+IL M  V GD ++G+CYVG+++   L  FV+IPL  YL++GT F+L+GF+AL  IR+ +K  GE+ TDKLEKLM+RI +F ++Y+VP   V+ C  YE +  D W+            Q+ T  C      P   +FM+K FM LVVG T+G WIWT KTL SW +V
Sbjct:    9 WLVLQVMGSCAAISSMDMERPGDGKCQPIEIPMCKDIGYNMTRMPNLMGHENQREAAIQLHEFAPLVEYGCHGHLRFFLCSLYAPMCTEQVSTPIPACRVMCEQARLKCSPIMEQFNFKWPDSLDCRKLPNKNDPNYLCMEAPNNG-SDEPTRGSGLFPPLFRPQRPHSAQEHPLKDGGPGRGGCDNPGKFHHVEKS--ASCAPLCTPGVDVYWSREDKRFAVVWLAIWAVLCFFSSAFTVLTFLIDPARFRYPERPIIFLSMCYCVYSVGYLIRLFAGAESIACDRDSGQLYVIQEGLE-STGCTLVFLVLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEANSSYFHLAAWAIPAVKTILILVMRRVAGDELTGVCYVGSMDVNALTGFVLIPLACYLVIGTSFILSGFVALFHIRRVMKTGGEN-TDKLEKLMVRIGLFSVLYTVPATCVIACYFYERLNMDYWKILAAQHKCKMNNQTKTLDCLMAASIPAVEIFMVKIFMLLVVGITSGMWIWTSKTLQSWQQV 534

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BLAST of Frizzled-5 vs. Ensembl Human
Match: FZD7 (frizzled class receptor 7 [Source:HGNC Symbol;Acc:HGNC:4045])

HSP 1 Score: 382.874 bits (982), Expect = 3.483e-125
Identity = 222/535 (41.50%), Postives = 308/535 (57.57%), Query Frame = 2

Query:  101 SISKPDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNA---CLRKDNK---------TRSNKTTNFVSERPYLLKSK-------------KCHCHCRSP-----LIIDSRDHFNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACK---SDAIRYGSSGAVP--CSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWE--------QSYTCPCRTKKY---QPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKL 1567
             IS PD     C PI I +C  I YN T +PN L H + E+AGLE+ QF  LV++ CS +LR FLCSMYAP+C       IP CRSLC  AR+GC  +MN++GF+WPE + CE  P   A   C+ ++             +  T  ++ + P+                   C    + P       +  RD       G  +N LM     YF E ++ F+  W+G+W+ +C  ST  T+LT+ +D  RF YPERPIIFLS CY +++V ++    L   AV  +    D  R  + G     C+I+F+ +YFFGMASSIWWV+L+ TWFLAAG+KWG EAI   +  +H  AW +P +++I IL M  VDGD +SG+CYVG  +   L  FV+ PL VYL +GT FLLAGF++L +IR  +K  G +KT+KLEKLM+RI +F ++Y+VP   V+ C  YE  FR+ WE        +SY  PC    +    P+++VFM+KY M ++VG T GFWIW+ KTL SW + + +L
Sbjct:   40 GISVPDH--GFCQPISIPLCTDIAYNQTILPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCT-VLDQAIPPCRSLCERARQGCEALMNKFGFQWPERLRCENFPVHGAGEICVGQNTSDGSGGPGGGPTAYPTAPYLPDLPFTALPPGASDGRGRPAFPFSCPRQLKVPPYLGYRFLGERDCGAPCEPGR-ANGLM-----YFKEEERRFARLWVGVWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYFMVAVAHVAGFLLEDRAVCVERFSDDGYRTVAQGTKKEGCTILFMVLYFFGMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQVDGDLLSGVCYVGLSSVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDG-TKTEKLEKLMVRIGVFSVLYTVPATIVLACYFYEQAFREHWERTWLLQTCKSYAVPCPPGHFPPMSPDFTVFMIKYLMTMIVGITTGFWIWSGKTLQSWRRFYHRL 564

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BLAST of Frizzled-5 vs. Ensembl Human
Match: FZD1 (frizzled class receptor 1 [Source:HGNC Symbol;Acc:HGNC:4038])

HSP 1 Score: 384.415 bits (986), Expect = 6.190e-125
Identity = 226/537 (42.09%), Postives = 303/537 (56.42%), Query Frame = 2

Query:  101 SISKPDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNACLRKDNKTRSNKTTNFVSERPYLLKSKKCHCHCRS------------------PLIIDSRDHFNKVVTGNISNCLMNCRSP------YFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACK----SDAIRYGSSGAVP--CSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWE--------QSYTCPCRTKK----------YQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKL 1567
             IS PD     C PI I +C  I YN T +PN L H + E+AGLE+ QF  LV++ CS +L+ FLCSMYAP+C       +P CRSLC  AR+GC  +MN++GF+WP+ + CEK P   A      +  S+K T   S  P    S   H                       P  +    + N    G   +C   C         YFG  +  FS  W+GIW+ +C  ST  T+LT+ +D  RF YPERPIIFLS CY  ++V Y+    L  + V C      D  R  + G     C+I+F+ +YFF MASSIWWV+L+ TWFLAAG+KWG EAI   +  +H  AW +P I++I IL +  VDGD +SG+C+VG  N   L  FV+ PL VYL +GT FLLAGF++L +IR  +K  G +KT+KLEKLM+RI +F ++Y+VP   V+ C  YE  FRD WE        +SY  PC   +            P+++VFM+KY M L+VG T+GFWIW+ KTL+SW K + +L
Sbjct:  107 GISVPDH--GYCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSAELKFFLCSMYAPVCT-VLEQALPPCRSLCERARQGCEALMNKFGFQWPDTLKCEKFPVHGAGELCVGQNTSDKGTPTPSLLPEFWTSNPQHGGGGHRGGFPGGAGASERGKFSCPRALKVPSYLNYHFLGE-KDCGAPCEPTKVYGLMYFGPEELRFSRTWIGIWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYTAVAVAYIAGFLL-EDRVVCNDKFAEDGARTVAQGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILALGQVDGDVLSGVCFVGLNNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDG-TKTEKLEKLMVRIGVFSVLYTVPATIVIACYFYEQAFRDQWERSWVAQSCKSYAIPCPHLQAGGGAPPHPPMSPDFTVFMIKYLMTLIVGITSGFWIWSGKTLNSWRKFYTRL 637

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BLAST of Frizzled-5 vs. Ensembl Human
Match: FZD2 (frizzled class receptor 2 [Source:HGNC Symbol;Acc:HGNC:4040])

HSP 1 Score: 375.941 bits (964), Expect = 1.356e-122
Identity = 217/542 (40.04%), Postives = 304/542 (56.09%), Query Frame = 2

Query:  101 SISKPDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNA---CLRKDNKTRSNKTTNFVSERP---------------------YLLKSKKCHCHCRSPLIIDSRDHFNKVVTGNISNCLMNCR------SPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKS----DAIRYGSSGAVP--CSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYT----------CPCR-TKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLCCRKS 1585
             IS PD     C PI I +C  I YN T +PN L H + E+AGLE+ QF  LV++ CS +LR FLCSMYAP+C       IP CRS+C  AR+GC  +MN++GF+WPE + CE  P   A   C+ +++           +  P                     Y       HC    P ++    + +    G   +C   C       S +F + +  F+  W+  W+ +C  ST  T+ T+ +D  RF+YPERPIIFLS CY ++SV Y+    L  E V C      D  R    G     C+I+F+ +YFF MASSIWWV+L+ TWFLAAG+KWG EAI   +  +H  AW +P +++I IL M  +DGD +SG+C+VG  +   L  FV+ PL VYL +GT FLLAGF++L +IR  +K  G +KT+KLE+LM+RI +F ++Y+VP   V+ C  YE  FR+ WE+S+           CP   T +  P+++V+M+KY M L+VG T+GFWIW+ KTL SW K + +L   R  
Sbjct:   30 GISIPDH--GFCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCT-VLEQAIPPCRSICERARQGCEALMNKFGFQWPERLRCEHFPRHGAEQICVGQNHSEDGAPALLTTAPPPGLQPGAGGTPGGPGGGGAPPRYATLEHPFHC----PRVLKVPSYLSYKFLGE-RDCAAPCEPARPDGSMFFSQEETRFARLWILTWSVLCCASTFFTVTTYLVDMQRFRYPERPIIFLSGCYTMVSVAYIAGFVL-QERVVCNERFSEDGYRTVVQGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQIDGDLLSGVCFVGLNSLDPLRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDG-TKTEKLERLMVRIGVFSVLYTVPATIVIACYFYEQAFREHWERSWVSQHCKSLAIPCPAHYTPRMSPDFTVYMIKYLMTLIVGITSGFWIWSGKTLHSWRKFYTRLTNSRHG 561

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BLAST of Frizzled-5 vs. Ensembl Celegans
Match: cfz-2 (Frizzled-2 [Source:UniProtKB/Swiss-Prot;Acc:G5ECQ2])

HSP 1 Score: 361.303 bits (926), Expect = 3.643e-117
Identity = 205/543 (37.75%), Postives = 303/543 (55.80%), Query Frame = 2

Query:   50 ISLLFSWVLFRICGQSFSISKPDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNACLRKDNKTRSNKTT---------------------NFVSERPYLLKSK----------KCHCHCRSPLIIDSRDHFNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDAIRYG--SSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGES--KTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPCRTKKYQPEYSVF--MLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKL 1567
            IS+LF  +L   CG  F       +   C  I I +CKGIGYN+T  PN   H   EEAGLE+ QF  LVE+ C + L+ FLC+MY PIC  N+   I  C  LC+ AR  C+ +M +YGF+WPE ++CE LP+ +  +   N   +   T                     N+  + P +  SK          +C C C  P    + +   K   GN++NC  +C SP   E   S  + W+  W+  C +  S T LTF I+  RFQYPERPI  L+ C L+++VG++IR  +GHE +AC S  I+    +SG++ C +VFL  YFFGMA+S+WWV+L+ TW L+A  KW  EAI  ++  +H   W +P IQ+++++  +++DGDP++GICYVGN +      FV+ PL+VY +VG  FL+ GF  L  IR  ++++  S     K+ +LM +I IF ++Y++P++ ++    YE   R LWEQS  C C  K+   + S+   ++K     ++G T+GFW+ + KTL SW    C L
Sbjct:    5 ISVLF--LLLGSCGALFG------KRQKCEQITIPLCKGIGYNMTSFPNSYGHEKQEEAGLEVHQFYPLVEVGCFQHLKFFLCTMYTPICQENYDKPILPCMELCVEARSKCSPIMAKYGFRWPETLSCEALPKMSDQMSTGNICAAPPDTPKKQHKGHHHKNQNQNQNQNHNYSPDGPEVGISKIDNEVIAGPSECQCTCNQPFQFVASE---KSKVGNVTNCAYSCHSPALAE-SHSLVSNWMAFWSITCCVLASFTFLTFLIETDRFQYPERPIFMLAFCQLMVAVGFMIRYFVGHEEIACDSMRIKGADDNSGSL-CFVVFLLTYFFGMAASVWWVILSLTWVLSAASKWSPEAISSFSFHFHVVGWCLPAIQTVLVIVFNAIDGDPITGICYVGNTDLQFQRIFVLFPLLVYFIVGVLFLVIGFCNLWSIRNEVQKQHPSLESAHKITQLMSKIGIFSLLYTIPSLLIICVLFYEQNHRSLWEQSQLCSCSPKQTIGDSSLIISLIKTCCMCILGWTSGFWVCSTKTLSSWKNAICCL 534

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BLAST of Frizzled-5 vs. Ensembl Celegans
Match: mom-5 (pep chromosome:WBcel235:I:9965580:9970037:1 gene:WBGene00003397.1 transcript:T23D8.1b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mom-5)

HSP 1 Score: 310.071 bits (793), Expect = 1.391e-97
Identity = 191/527 (36.24%), Postives = 275/527 (52.18%), Query Frame = 2

Query:  134 CIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNACLRKDNKT--------RSNKTTNFVS--ERPYLLKSKKCHCHCRSPLIIDSRDHFN-KVVTGNISNCLMNCRSP-----YFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDAIRYGSSGA---------VPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKG---ESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSY---------------------TCPCRTKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKL 1567
            C  I I MCK + YN T  PN L H +  EAG  I QFN L+++ CSED+RLFLC++YAP+C       I  CR LC+SA+ GC  +M ++GF+WP+ ++C K P  + C+ K++           SN  T  VS      +L  KKC  H  +     S  HF+  +++G +  C + C +       F    +     W   W+  C + +  T++TF +D SRF YP RPI++L+ CYL +S  Y+I V +G +  AC +    YGS+           V CS + +  YFF M+S  WW+VL   WFLAA LKWG+E+I   +  +H   W +P + S+ +L  +SVDGD  +GIC VGNLN   L++F   P++V L +G   L+ G  ++++IR  IK +    E    KLEKLM+RI  F I+YS+PT        Y+ +    W + +                      CP   K   PE  VF+LKY   LVVG T   W+ + KTL S+ K +  L
Sbjct:   37 CEHITIPMCKNLDYNQTVFPNLLGHTTQSEAGPAIAQFNPLIKVKCSEDIRLFLCTVYAPVC-TVLEKPIQPCRELCLSAKNGCESLMKKFGFQWPDQLDCNKFPVTDLCVGKNSSESSNSKNYRSSNDVTFGVSTIANEVVLSPKKCPHHMHT----TSGSHFSLPLLSGRLPECSLTCEADNQVPMMFDGRVRRILRIWTAAWSVACFVCSLFTLVTFLVDLSRFAYPVRPILYLAFCYLAISTVYMIGV-VGEDGFACGT----YGSTPTTLVTQGGENVGCSALAVVHYFFFMSSCAWWLVLCLAWFLAANLKWGAESIAALSPYFHAMCWGVPAVLSVTVLVTNSVDGDVFTGICSVGNLNPSALVYFFFTPIVVSLALGAVLLVCGIWSMIRIRSYIKLQHADVERNISKLEKLMLRIGAFAIMYSLPTAMNAAIMWYQAVNMPAWLEGWLHHRCVRLQDRELFGFTYPVDDCPMDPKVAAPEIIVFLLKYVSQLVVGITCAIWVVSSKTLSSYHKAYLAL 553

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BLAST of Frizzled-5 vs. Ensembl Celegans
Match: mom-5 (pep chromosome:WBcel235:I:9965580:9969413:1 gene:WBGene00003397.1 transcript:T23D8.1a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mom-5)

HSP 1 Score: 306.605 bits (784), Expect = 2.837e-96
Identity = 191/525 (36.38%), Postives = 275/525 (52.38%), Query Frame = 2

Query:  134 CIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNACL------RKDNKTRSNKTTNFVS--ERPYLLKSKKCHCHCRSPLIIDSRDHFN-KVVTGNISNCLMNCRSP-----YFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDAIRYGSSGA---------VPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKG---ESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSY---------------------TCPCRTKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKL 1567
            C  I I MCK + YN T  PN L H +  EAG  I QFN L+++ CSED+RLFLC++YAP+C       I  CR LC+SA+ GC  +M ++GF+WP+ ++C K P  + C+        ++K  SN  T  VS      +L  KKC  H  +     S  HF+  +++G +  C + C +       F    +     W   W+  C + +  T++TF +D SRF YP RPI++L+ CYL +S  Y+I V +G +  AC +    YGS+           V CS + +  YFF M+S  WW+VL   WFLAA LKWG+E+I   +  +H   W +P + S+ +L  +SVDGD  +GIC VGNLN   L++F   P++V L +G   L+ G  ++++IR  IK +    E    KLEKLM+RI  F I+YS+PT        Y+ +    W + +                      CP   K   PE  VF+LKY   LVVG T   W+ + KTL S+ K +  L
Sbjct:   37 CEHITIPMCKNLDYNQTVFPNLLGHTTQSEAGPAIAQFNPLIKVKCSEDIRLFLCTVYAPVC-TVLEKPIQPCRELCLSAKNGCESLMKKFGFQWPDQLDCNKFPVTDLCVGKNSSESSNSKKSSNDVTFGVSTIANEVVLSPKKCPHHMHT----TSGSHFSLPLLSGRLPECSLTCEADNQVPMMFDGRVRRILRIWTAAWSVACFVCSLFTLVTFLVDLSRFAYPVRPILYLAFCYLAISTVYMIGV-VGEDGFACGT----YGSTPTTLVTQGGENVGCSALAVVHYFFFMSSCAWWLVLCLAWFLAANLKWGAESIAALSPYFHAMCWGVPAVLSVTVLVTNSVDGDVFTGICSVGNLNPSALVYFFFTPIVVSLALGAVLLVCGIWSMIRIRSYIKLQHADVERNISKLEKLMLRIGAFAIMYSLPTAMNAAIMWYQAVNMPAWLEGWLHHRCVRLQDRELFGFTYPVDDCPMDPKVAAPEIIVFLLKYVSQLVVGITCAIWVVSSKTLSSYHKAYLAL 551

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BLAST of Frizzled-5 vs. Ensembl Celegans
Match: lin-17 (Transmembrane receptor LIN-17 [Source:UniProtKB/TrEMBL;Acc:G5EDV1])

HSP 1 Score: 226.098 bits (575), Expect = 6.413e-66
Identity = 143/498 (28.71%), Postives = 244/498 (49.00%), Query Frame = 2

Query:  134 CIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNACLRKDNKTRSNKTTNFVSERPYLLKSKKCHCHCRSPL-----IIDSRDHFNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSV-TILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKS--DAIRYGSSGAVP---CSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLW--------EQSYTCPCRTKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSK-VFCKL 1567
            CIPI+I +CK + YN TY PN + H          + F  L++  C   +  F+CS++AP+C    P  + +C+S+C   +  C  ++ ++G  WPE +NC + P+      K   T    T  F + R   L +K        P      ++D   H  K      S+C   C+S      D         IW        ++ + LTF ID+ RF++PER + +LS+C  + S+ YL  + +     +C +  +   Y S G      C   FL  YFF  A+++WW++ + T +L+ G KW  E I   +   HF AW +  + +II+L  + VD   ++ +C VGNLN   LL+FVI+P  + +++GT F++ GF ++ + R + + +G + T KLEKLM+++  F  ++ +P +  + C  Y+F+    W        +QS  C    +   P+  ++M     +L  G +   W+ + KT+ +W   +FC +
Sbjct:   28 CIPIDIELCKDLPYNYTYFPNTILHNDQHTLQTHTEHFKPLMKTKCHPHIHFFICSVFAPMCPIGMPQAVTSCKSVCEQVKADCFSILEEFGIGWPEPLNCAQFPDPPELCMK--PTEDEITGGFSAPR---LPTKGSSSSSSKPTGCPSDLVDVDPHDPK------SHCAFACQSNVMFSTDNKRMVRSWSIWFAAANAGVALFSFLTFAIDRKRFRFPERCVFYLSLCIFISSLPYLTPLFIDAPIRSCHALGNGRSYLSIGTFDNSYCLASFLLNYFFSTAAALWWLMFSFTLYLSGGRKWVPEGIEACSSYVHFVAWGLSSLATIIVLIFNKVDASELTALCSVGNLNSIALLWFVIVPRTICIVIGTCFIVGGFASMCRERISFRTRG-TDTSKLEKLMVKMGFFCALFILPNVIELVCQCYKFMILTQWTRMTIDCKQQSGAC---HRPTPPQAEIYMTAVISSLATGFSCLMWVLSAKTVHAWKNFIFCGM 510

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Query:  134 CIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNACLRKDNKTRSNKTTNFVSERPYLLKSKKCHCHCRSPL-----IIDSRDHFNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSV-TILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKS--DAIRYGSSGAVP---CSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLW--------EQSYTCPCRTKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSK-VFCKL 1567
            CIPI+I +CK + YN TY PN + H          + F  L++  C   +  F+CS++AP+C    P  + +C+S+C   +  C  ++ ++G  WPE +NC + P+      K   T    T  F + R   L +K        P      ++D   H  K      S+C   C+S      D         IW        ++ + LTF ID+ RF++PER + +LS+C  + S+ YL  + +     +C +  +   Y S G      C   FL  YFF  A+++WW++ + T +L+ G KW  E I   +   HF AW +  + +II+L  + VD   ++ +C VGNLN   LL+FVI+P  + +++GT F++ GF ++ + R + + +G + T KLEKLM+++  F  ++ +P +  + C  Y+F+    W        +QS  C    +   P+  ++M     +L  G +   W+ + KT+ +W   +FC +
Sbjct:   28 CIPIDIELCKDLPYNYTYFPNTILHNDQHTLQTHTEHFKPLMKTKCHPHIHFFICSVFAPMCPIGMPQAVTSCKSVCEQVKADCFSILEEFGIGWPEPLNCAQFPDPPELCMK--PTEDEITGGFSAPR---LPTKGSSSSSSKPTGCPSDLVDVDPHDPK------SHCAFACQSNVMFSTDNKRMVRSWSIWFAAANAGVALFSFLTFAIDRKRFRFPERCVFYLSLCIFISSLPYLTPLFIDAPIRSCHALGNGRSYLSIGTFDNSYCLASFLLNYFFSTAAALWWLMFSFTLYLSGGRKWVPEGIEACSSYVHFVAWGLSSLATIIVLIFNKVDASELTALCSVGNLNSIALLWFVIVPRTICIVIGTCFIVGGFASMCRERISFRTRG-TDTSKLEKLMVKMGFFCALFILPNVIELVCQCYKFMILTQWTRMTIDCKQQSGAC---HRPTPPQAEIYMTAVISSLATGFSCLMWVLSAKTVHAWKNFIFCGM 510

[Close]

BLAST of Frizzled-5 vs. Ensembl Fly
Match: fz2 (gene:FBgn0016797 transcript:FBtr0112890)

HSP 1 Score: 457.603 bits (1176), Expect = 4.934e-153
Identity = 248/565 (43.89%), Postives = 334/565 (59.12%), Query Frame = 2

Query:  113 PDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLP----EDNACLRKDNKT------------------------------------------------RSNKTTNFVSERPYLLKSKKCHCHCRSPLIIDSRD------------------HFNKVVT--GNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDAIRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKG----ESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPCRTKK---YQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLL 1570
            P+LR   C  I I MC+GIGYN+T  PN++NH + +EAGLE+ QF  LVEI CS DL+ FLCSMY PICL ++   +P CRS+C  AR GC  +M QY F+WPE M CE LP     DN C+ + + T                                                R   + N  + +      K+C C CRSPLI   ++                  + N  V     + NC + C+ P+F   +K F+  W+ +W+ +C  ST +T+ TF ID  RF+YPERPI+FLS CY +++VGYL R  L +E +AC    +R  S+G   C++VFL  YFFGMASSIWWV+L+ TWFLAAGLKWG+EAI  ++  +H  AW IP +QS+ +L +S+VDGDP+ GICYVGNLN  +L  FV+ PL VYL++GT FL+AGF++L +IR  IK++G      K DKLEKLMIRI IF ++Y+VP   V+ C +YE  + + W ++  CPC   K    +P YSV MLKYFM L VG T+G WIW+ KTL+SW + + +LL
Sbjct:   60 PNLR---CEEITIPMCRGIGYNMTSFPNEMNHETQDEAGLEVHQFWPLVEIKCSPDLKFFLCSMYTPICLEDYHKPLPVCRSVCERARSGCAPIMQQYSFEWPERMACEHLPLHGDPDNLCMEQPSYTEAGSGGSSGGSGGSGSGSGSGGKRKQGGSGSGGSGAGGSSGSTSTKPCRGRNSKNCQNPQGEKASGKECSCSCRSPLIFLGKEQLLQQQSQMPMMHHPHHWYMNLTVQRIAGVPNCGIPCKGPFFSNDEKDFAGLWIALWSGLCFCSTLMTLTTFIIDTERFKYPERPIVFLSACYFMVAVGYLSRNFLQNEEIACDGLLLRESSTGPHSCTLVFLLTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQYFHLAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGVGAGVKADKLEKLMIRIGIFSVLYTVPATIVIGCYLYEAAYFEDWIKALACPCAQVKGPGKKPLYSVLMLKYFMALAVGITSGVWIWSGKTLESWRRFWRRLL 621

[Close]

BLAST of Frizzled-5 vs. Ensembl Fly
Match: fz2 (gene:FBgn0016797 transcript:FBtr0075029)

HSP 1 Score: 457.603 bits (1176), Expect = 4.934e-153
Identity = 248/565 (43.89%), Postives = 334/565 (59.12%), Query Frame = 2

Query:  113 PDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLP----EDNACLRKDNKT------------------------------------------------RSNKTTNFVSERPYLLKSKKCHCHCRSPLIIDSRD------------------HFNKVVT--GNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDAIRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKG----ESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPCRTKK---YQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLL 1570
            P+LR   C  I I MC+GIGYN+T  PN++NH + +EAGLE+ QF  LVEI CS DL+ FLCSMY PICL ++   +P CRS+C  AR GC  +M QY F+WPE M CE LP     DN C+ + + T                                                R   + N  + +      K+C C CRSPLI   ++                  + N  V     + NC + C+ P+F   +K F+  W+ +W+ +C  ST +T+ TF ID  RF+YPERPI+FLS CY +++VGYL R  L +E +AC    +R  S+G   C++VFL  YFFGMASSIWWV+L+ TWFLAAGLKWG+EAI  ++  +H  AW IP +QS+ +L +S+VDGDP+ GICYVGNLN  +L  FV+ PL VYL++GT FL+AGF++L +IR  IK++G      K DKLEKLMIRI IF ++Y+VP   V+ C +YE  + + W ++  CPC   K    +P YSV MLKYFM L VG T+G WIW+ KTL+SW + + +LL
Sbjct:   60 PNLR---CEEITIPMCRGIGYNMTSFPNEMNHETQDEAGLEVHQFWPLVEIKCSPDLKFFLCSMYTPICLEDYHKPLPVCRSVCERARSGCAPIMQQYSFEWPERMACEHLPLHGDPDNLCMEQPSYTEAGSGGSSGGSGGSGSGSGSGGKRKQGGSGSGGSGAGGSSGSTSTKPCRGRNSKNCQNPQGEKASGKECSCSCRSPLIFLGKEQLLQQQSQMPMMHHPHHWYMNLTVQRIAGVPNCGIPCKGPFFSNDEKDFAGLWIALWSGLCFCSTLMTLTTFIIDTERFKYPERPIVFLSACYFMVAVGYLSRNFLQNEEIACDGLLLRESSTGPHSCTLVFLLTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQYFHLAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGVGAGVKADKLEKLMIRIGIFSVLYTVPATIVIGCYLYEAAYFEDWIKALACPCAQVKGPGKKPLYSVLMLKYFMALAVGITSGVWIWSGKTLESWRRFWRRLL 621

[Close]

BLAST of Frizzled-5 vs. Ensembl Fly
Match: fz2 (gene:FBgn0016797 transcript:FBtr0332735)

HSP 1 Score: 457.603 bits (1176), Expect = 4.934e-153
Identity = 248/565 (43.89%), Postives = 334/565 (59.12%), Query Frame = 2

Query:  113 PDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLP----EDNACLRKDNKT------------------------------------------------RSNKTTNFVSERPYLLKSKKCHCHCRSPLIIDSRD------------------HFNKVVT--GNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDAIRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKG----ESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPCRTKK---YQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLL 1570
            P+LR   C  I I MC+GIGYN+T  PN++NH + +EAGLE+ QF  LVEI CS DL+ FLCSMY PICL ++   +P CRS+C  AR GC  +M QY F+WPE M CE LP     DN C+ + + T                                                R   + N  + +      K+C C CRSPLI   ++                  + N  V     + NC + C+ P+F   +K F+  W+ +W+ +C  ST +T+ TF ID  RF+YPERPI+FLS CY +++VGYL R  L +E +AC    +R  S+G   C++VFL  YFFGMASSIWWV+L+ TWFLAAGLKWG+EAI  ++  +H  AW IP +QS+ +L +S+VDGDP+ GICYVGNLN  +L  FV+ PL VYL++GT FL+AGF++L +IR  IK++G      K DKLEKLMIRI IF ++Y+VP   V+ C +YE  + + W ++  CPC   K    +P YSV MLKYFM L VG T+G WIW+ KTL+SW + + +LL
Sbjct:   60 PNLR---CEEITIPMCRGIGYNMTSFPNEMNHETQDEAGLEVHQFWPLVEIKCSPDLKFFLCSMYTPICLEDYHKPLPVCRSVCERARSGCAPIMQQYSFEWPERMACEHLPLHGDPDNLCMEQPSYTEAGSGGSSGGSGGSGSGSGSGGKRKQGGSGSGGSGAGGSSGSTSTKPCRGRNSKNCQNPQGEKASGKECSCSCRSPLIFLGKEQLLQQQSQMPMMHHPHHWYMNLTVQRIAGVPNCGIPCKGPFFSNDEKDFAGLWIALWSGLCFCSTLMTLTTFIIDTERFKYPERPIVFLSACYFMVAVGYLSRNFLQNEEIACDGLLLRESSTGPHSCTLVFLLTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQYFHLAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGVGAGVKADKLEKLMIRIGIFSVLYTVPATIVIGCYLYEAAYFEDWIKALACPCAQVKGPGKKPLYSVLMLKYFMALAVGITSGVWIWSGKTLESWRRFWRRLL 621

[Close]

BLAST of Frizzled-5 vs. Ensembl Fly
Match: fz2 (gene:FBgn0016797 transcript:FBtr0330194)

HSP 1 Score: 457.603 bits (1176), Expect = 4.934e-153
Identity = 248/565 (43.89%), Postives = 334/565 (59.12%), Query Frame = 2

Query:  113 PDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLP----EDNACLRKDNKT------------------------------------------------RSNKTTNFVSERPYLLKSKKCHCHCRSPLIIDSRD------------------HFNKVVT--GNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDAIRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKG----ESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPCRTKK---YQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLL 1570
            P+LR   C  I I MC+GIGYN+T  PN++NH + +EAGLE+ QF  LVEI CS DL+ FLCSMY PICL ++   +P CRS+C  AR GC  +M QY F+WPE M CE LP     DN C+ + + T                                                R   + N  + +      K+C C CRSPLI   ++                  + N  V     + NC + C+ P+F   +K F+  W+ +W+ +C  ST +T+ TF ID  RF+YPERPI+FLS CY +++VGYL R  L +E +AC    +R  S+G   C++VFL  YFFGMASSIWWV+L+ TWFLAAGLKWG+EAI  ++  +H  AW IP +QS+ +L +S+VDGDP+ GICYVGNLN  +L  FV+ PL VYL++GT FL+AGF++L +IR  IK++G      K DKLEKLMIRI IF ++Y+VP   V+ C +YE  + + W ++  CPC   K    +P YSV MLKYFM L VG T+G WIW+ KTL+SW + + +LL
Sbjct:   60 PNLR---CEEITIPMCRGIGYNMTSFPNEMNHETQDEAGLEVHQFWPLVEIKCSPDLKFFLCSMYTPICLEDYHKPLPVCRSVCERARSGCAPIMQQYSFEWPERMACEHLPLHGDPDNLCMEQPSYTEAGSGGSSGGSGGSGSGSGSGGKRKQGGSGSGGSGAGGSSGSTSTKPCRGRNSKNCQNPQGEKASGKECSCSCRSPLIFLGKEQLLQQQSQMPMMHHPHHWYMNLTVQRIAGVPNCGIPCKGPFFSNDEKDFAGLWIALWSGLCFCSTLMTLTTFIIDTERFKYPERPIVFLSACYFMVAVGYLSRNFLQNEEIACDGLLLRESSTGPHSCTLVFLLTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQYFHLAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGVGAGVKADKLEKLMIRIGIFSVLYTVPATIVIGCYLYEAAYFEDWIKALACPCAQVKGPGKKPLYSVLMLKYFMALAVGITSGVWIWSGKTLESWRRFWRRLL 621

[Close]

BLAST of Frizzled-5 vs. Ensembl Fly
Match: fz2 (gene:FBgn0016797 transcript:FBtr0075028)

HSP 1 Score: 457.603 bits (1176), Expect = 4.934e-153
Identity = 248/565 (43.89%), Postives = 334/565 (59.12%), Query Frame = 2

Query:  113 PDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLP----EDNACLRKDNKT------------------------------------------------RSNKTTNFVSERPYLLKSKKCHCHCRSPLIIDSRD------------------HFNKVVT--GNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDAIRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKG----ESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPCRTKK---YQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLL 1570
            P+LR   C  I I MC+GIGYN+T  PN++NH + +EAGLE+ QF  LVEI CS DL+ FLCSMY PICL ++   +P CRS+C  AR GC  +M QY F+WPE M CE LP     DN C+ + + T                                                R   + N  + +      K+C C CRSPLI   ++                  + N  V     + NC + C+ P+F   +K F+  W+ +W+ +C  ST +T+ TF ID  RF+YPERPI+FLS CY +++VGYL R  L +E +AC    +R  S+G   C++VFL  YFFGMASSIWWV+L+ TWFLAAGLKWG+EAI  ++  +H  AW IP +QS+ +L +S+VDGDP+ GICYVGNLN  +L  FV+ PL VYL++GT FL+AGF++L +IR  IK++G      K DKLEKLMIRI IF ++Y+VP   V+ C +YE  + + W ++  CPC   K    +P YSV MLKYFM L VG T+G WIW+ KTL+SW + + +LL
Sbjct:   60 PNLR---CEEITIPMCRGIGYNMTSFPNEMNHETQDEAGLEVHQFWPLVEIKCSPDLKFFLCSMYTPICLEDYHKPLPVCRSVCERARSGCAPIMQQYSFEWPERMACEHLPLHGDPDNLCMEQPSYTEAGSGGSSGGSGGSGSGSGSGGKRKQGGSGSGGSGAGGSSGSTSTKPCRGRNSKNCQNPQGEKASGKECSCSCRSPLIFLGKEQLLQQQSQMPMMHHPHHWYMNLTVQRIAGVPNCGIPCKGPFFSNDEKDFAGLWIALWSGLCFCSTLMTLTTFIIDTERFKYPERPIVFLSACYFMVAVGYLSRNFLQNEEIACDGLLLRESSTGPHSCTLVFLLTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQYFHLAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGVGAGVKADKLEKLMIRIGIFSVLYTVPATIVIGCYLYEAAYFEDWIKALACPCAQVKGPGKKPLYSVLMLKYFMALAVGITSGVWIWSGKTLESWRRFWRRLL 621

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BLAST of Frizzled-5 vs. Ensembl Zebrafish
Match: fzd5 (frizzled class receptor 5 [Source:ZFIN;Acc:ZDB-GENE-990415-218])

HSP 1 Score: 508.834 bits (1309), Expect = 3.100e-174
Identity = 266/542 (49.08%), Postives = 363/542 (66.97%), Query Frame = 2

Query:   47 GISLLFSWV----LFRICGQSFSISKPDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLP----EDNACLRKDNKTRSNKTTNFVSERP-------YLLKS---KKC--HCHCRSPLI-IDSRDH--FNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDA----IRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPCRTKKYQ----PEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLCCR 1579
            G+ L+  W+    LF++ G   S SK D+    C PI + MCKGIGYN TY+PN  NH + +E GLE+ QF  LV I+CS DL  FLCSMY PICL ++   +P CRS+C  A+ GC+ +M QYGF+WPE M+CE+LP     D  C+ +++   +  +  F    P          KS   +KC   CHCR PL+ I    H   N+V TG++ NC + C  PYF + +++F+TFW+G+W+ +C +ST  T+ TF ID  RF+YPERPIIFL+ CYL +S+GY++R+  GHE VAC+       I Y ++G   C++VFL IYFFGMASSIWWVVL+ TWFLAAG+KWG+EAI  Y+  +H  AW +P ++SI +L +SSVDGDPV+GICYVGN +   L  FV+ PL+VYL  G+ FLLAGF++L +IR  IK+ G +KTDKLEKLMIRI +F ++Y+VP   VV C +YE  +R  WE++  C C +++ +    P+Y+VFMLKYFM LVVG T+G WIW+ KTL+SW +   + + CR
Sbjct:   16 GMHLVGFWLHVLLLFQLSGLGDSASK-DI---VCEPITVPMCKGIGYNHTYMPNQFNHDNQDEVGLEVHQFWPLVRIHCSPDLLFFLCSMYTPICLQDYKKPLPPCRSVCERAKRGCSPLMIQYGFEWPERMSCEQLPMLGDTDRLCMDRNSSETTTLSPPFPKPTPKGTPRHRATAKSAPPQKCDRECHCRGPLVPIKKEAHPLHNRVNTGSLPNCALPCHQPYFSQDERTFTTFWIGLWSVLCFVSTFTTVATFLIDMERFKYPERPIIFLAACYLFVSLGYIVRLLAGHERVACEGTGDQQHILYDTTGPALCTLVFLLIYFFGMASSIWWVVLSFTWFLAAGMKWGNEAIAGYSQYFHLAAWLVPSVKSIAVLALSSVDGDPVAGICYVGNQSLEGLRGFVLAPLVVYLFTGSLFLLAGFVSLFRIRSVIKQGG-TKTDKLEKLMIRIGLFTVLYTVPATIVVACLVYEQHYRPSWERALACSCPSERQRLGMGPDYAVFMLKYFMCLVVGITSGVWIWSGKTLESWRRFIARYVPCR 552

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BLAST of Frizzled-5 vs. Ensembl Zebrafish
Match: fzd8b (frizzled class receptor 8b [Source:ZFIN;Acc:ZDB-GENE-000328-4])

HSP 1 Score: 499.975 bits (1286), Expect = 4.476e-171
Identity = 250/511 (48.92%), Postives = 344/511 (67.32%), Query Frame = 2

Query:  122 RPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLP---EDNACLRKDNKTRSNKT-----TNFVSERPYLLKSKKC--------HCHCRSPLIIDSRDH---FNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKS----DAIRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPCRTKKY--QPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLCCR 1579
            R   C  I + +C+GIGYN TY+PN  NH + +EAGLE+ QF  LVEI CS DLR FLCSMY PICL ++   +P CRS+C  A+ GC  +M QYGF WP+ M C+ LP   + N      N+T +  +     T     +P+  K+K           C+CR+P++    DH   +N+V TG I NC M C +PY  + +++F+TFW+GIW+ +C +ST  T++TF ID  RF+YPERPIIFLS CY+ +S+GY+IR+  GHE VAC      D I Y ++G   C++VFL IYFFGMAS+IWWV+L+ TWFLAAGLKWG+EAI  Y+  +H  AW IP ++SI +L +SSVDGD ++GICYVGN N  NL  FV+ PL++YL +GT FL AGF+++ +IR  IK+ G +KTDKLE+LM+RI +F ++Y+V  + +V C +YE   R+ WE ++ C C + K   +P+Y+VFMLKYFM L++G T+G W W+ KTLDSW  +  +  CCR
Sbjct:   27 REHVCQEISVPLCRGIGYNYTYMPNQFNHDNQDEAGLEVHQFWPLVEIQCSPDLRFFLCSMYTPICLEDYKKPLPPCRSVCERAKAGCAPLMRQYGFPWPDRMRCDLLPVQGDPNTLCMDYNRTDATSSPAAPKTTSRPGKPFKRKNKSSPGSSSCEPECYCRAPMVPVHSDHHPLYNRVKTGQIPNCAMPCHNPYLSQEERTFATFWIGIWSVLCFLSTFATVITFLIDIERFKYPERPIIFLSACYMFVSLGYIIRLIAGHERVACNQNHEVDHIHYETTGPALCTLVFLLIYFFGMASAIWWVILSFTWFLAAGLKWGNEAIARYSQYFHMAAWLIPSVKSITVLALSSVDGDSIAGICYVGNQNLDNLRGFVLAPLVIYLFIGTIFLFAGFVSMFRIRSVIKQGG-TKTDKLERLMVRIGVFTVLYTVVAIMIVACYVYEHHNREAWEIAHACNCSSDKKAPKPDYAVFMLKYFMCLLIGITSGAWTWSSKTLDSWRALCTRCCCCR 536

[Close]

BLAST of Frizzled-5 vs. Ensembl Zebrafish
Match: fzd8b (frizzled class receptor 8b [Source:ZFIN;Acc:ZDB-GENE-000328-4])

HSP 1 Score: 499.59 bits (1285), Expect = 7.699e-171
Identity = 250/511 (48.92%), Postives = 343/511 (67.12%), Query Frame = 2

Query:  122 RPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLP---EDNACLRKDNKTRSNKT-----TNFVSERPYLLKSKKC--------HCHCRSPLIIDSRDH---FNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKS----DAIRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPCRTKKY--QPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLCCR 1579
            R   C  I + +C+GIGYN TY+PN  NH + +EAGLE+ QF  LVEI CS DLR FLCSMY PICL ++   +P CRS+C  A+ GC  +M QYGF WP+ M C+ LP   + N      N+T +  +     T     +P+  K+K           C+CR+P++    DH   +N+V TG I NC M C +PY  + +++F+TFW+GIW+ +C +ST  T+ TF ID  RF+YPERPIIFLS CY+ +S+GY+IR+  GHE VAC      D I Y ++G   C++VFL IYFFGMAS+IWWV+L+ TWFLAAGLKWG+EAI  Y+  +H  AW IP ++SI +L +SSVDGD ++GICYVGN N  NL  FV+ PL++YL +GT FL AGF+++ +IR  IK+ G +KTDKLE+LM+RI +F ++Y+V  + +V C +YE   R+ WE ++ C C + K   +P+Y+VFMLKYFM L++G T+G W W+ KTLDSW  +  +  CCR
Sbjct:   27 REHVCQEISVPLCRGIGYNYTYMPNQFNHDNQDEAGLEVHQFWPLVEIQCSPDLRFFLCSMYTPICLEDYKKPLPPCRSVCERAKAGCAPLMRQYGFPWPDRMRCDLLPVQGDPNTLCMDYNRTDATSSPAAPKTTSRPGKPFKRKNKSSPGSSSCEPECYCRAPMVPVHSDHHPLYNRVKTGQIPNCAMPCHNPYLSQEERTFATFWIGIWSVLCFLSTFATVATFLIDIERFKYPERPIIFLSACYMFVSLGYIIRLIAGHERVACNQNHEVDHIHYETTGPALCTLVFLLIYFFGMASAIWWVILSFTWFLAAGLKWGNEAIARYSQYFHMAAWLIPSVKSITVLALSSVDGDSIAGICYVGNQNLDNLRGFVLAPLVIYLFIGTIFLFAGFVSMFRIRSVIKQGG-TKTDKLERLMVRIGVFTVLYTVVAIMIVACYVYEHHNREAWEIAHACNCSSDKKAPKPDYAVFMLKYFMCLLIGITSGAWTWSSKTLDSWRALCTRCCCCR 536

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BLAST of Frizzled-5 vs. Ensembl Zebrafish
Match: fzd8a (frizzled class receptor 8a [Source:ZFIN;Acc:ZDB-GENE-000328-3])

HSP 1 Score: 498.819 bits (1283), Expect = 1.720e-170
Identity = 263/514 (51.17%), Postives = 351/514 (68.29%), Query Frame = 2

Query:  131 TCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLP----EDNACL---RKDNKTRS---NKTTNFVSE----------RPYLL--KSKKCH--CHCRSPLI-IDSRDH--FNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSD----AIRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPCRTKKY--QPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLC 1573
            TC  I + +CKGIGYN TY+PN  NH + +EAGLE+ QF  LVEI CS DL+ FLCSMY PICL ++   +P CRS+C  A+ GC  +M QYGF WP+ M C+ LP     D  C+   R D+ T S   +K TN+ S+          RP +   K+K C   C CR+P++ ++S  H  +N+V TG I NC M C +PYF + +++F+ FW+G+W+ +C IST  T+ TF ID  RF+YPERPIIFLS CY+ +S+GY++R+  GHE VAC  +     I Y ++G   C++VFL IYFFGMASSIWWV+L+ TWFLAAG+KWG+EAI  Y+  +H  AW IP ++SI +L +SSVDGDPV+GICYVGN N  NL  FV+ PL++YL +GT FLLAGF++L +IR  IK+ G +KTDKLEKLMIRI IF ++Y+VP   +V C  YE   R  WE ++ C C  ++   +P+Y+VFMLKYFM L+VG T+G W W+ KTL+SW + FC   C
Sbjct:   29 TCQEIAVPLCKGIGYNYTYMPNQFNHDTQDEAGLEVHQFWPLVEIQCSPDLKFFLCSMYTPICLEDYKKPLPPCRSVCERAKAGCAPLMRQYGFPWPDRMRCDLLPVQGAPDTLCMDYNRTDSTTVSPVLSKPTNYPSKAINPHKKKSGRPGVGPNKNKPCEPGCQCRAPMVPVNSDRHPLYNRVKTGQIPNCAMPCHNPYFTQDERTFTAFWIGLWSVLCFISTFATVATFLIDMERFKYPERPIIFLSACYMFVSIGYIVRLIAGHEKVACNREYDVEHIHYETTGPALCTVVFLLIYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYSQYFHLAAWLIPSMKSIAVLALSSVDGDPVAGICYVGNQNLDNLRGFVLAPLVIYLFIGTMFLLAGFVSLFRIRSVIKQGG-TKTDKLEKLMIRIGIFTVLYTVPATIIVACYFYEQHNRQSWEITHNCSCLLEQEIKRPDYAVFMLKYFMCLLVGITSGVWTWSGKTLESW-RSFCTRCC 540

[Close]

BLAST of Frizzled-5 vs. Ensembl Zebrafish
Match: fzd9b (frizzled class receptor 9b [Source:ZFIN;Acc:ZDB-GENE-000906-4])

HSP 1 Score: 394.815 bits (1013), Expect = 6.258e-130
Identity = 224/540 (41.48%), Postives = 316/540 (58.52%), Query Frame = 2

Query:   68 WVLFRICGQSFSISKPDL---RPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNA----CL---RKDNKTRSNKTTNFVSERPYLLKSKKCHCHCRSPL-IIDSRDHFNKVVTGNISNCLMNCRSP---YFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDA-----IRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFI------FRDLWEQSYTCP------CRTKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLCCRKSLHH 1594
            W    I   S  I   DL   RP+ C PI I MC+GIGYNLT +PN ++H +  EA +++ +F  LVE  C   LR FLCS+YAP+C       IPACR +C  AR+ C+ +M ++ + WPE +NC KLP  N     C+     D KT + K    +   P   +    +      + + ++ + F  V       C   C S    ++   DK F+  W+ +W+ +C +ST+ T+LTF +D  RFQYPERPIIFLS+CY + SV ++IR   G E +AC  +      I+ G   +  C+IVFL +Y+FGMASSIWWV+LT TWFLAAG KWG EAI  ++  +H  AW IP +++I+ILTM  V GD ++G+CYVG+++   L  FV++PL  YL++GT F+L GF+AL  IRK +K +G + T+KLEKLM++I I+ I+Y+VP   V+ C  YE +      FR L  +  T P      C      P  +VFMLK FM+LVVG T+G W+W+ KTL +W  +  + L  R    H
Sbjct:   13 WCHLVIAAYSLEIGSYDLERGRPAKCEPIVIPMCQGIGYNLTRMPNFMDHDNQREAAIKLNEFAPLVEYGCDVHLRFFLCSLYAPMCTDQVSTSIPACRPMCEQARQKCSPIMEKFNYAWPESLNCSKLPTRNDPNALCMEAPENDTKTETKKGEGMLPVPPRPRQPGAGNARSGGTMGVCENPEKFQYVEKSE--TCAPRCSSAVDVFWSRQDKDFAFIWMAVWSTLCFVSTAFTVLTFLLDPHRFQYPERPIIFLSMCYNVYSVAFIIRSVAGAENIACDRENGELYIIQEGLE-STGCTIVFLILYYFGMASSIWWVILTLTWFLAAGKKWGHEAIESHSSYFHMAAWGIPALKTIVILTMRKVAGDELTGLCYVGSMDVGALTGFVLVPLSCYLVIGTSFILTGFVALFHIRKVMKTEG-TNTEKLEKLMVKIGIYSILYTVPATCVIICYFYERLNMDYWKFRGLQSKCTTFPGRRNEDCSLDSSVPTVAVFMLKIFMSLVVGITSGVWVWSSKTLQTWQGLCSRKLTDRTCRKH 548

[Close]

BLAST of Frizzled-5 vs. Ensembl Xenopus
Match: zdhhc9 (zinc finger DHHC-type containing 9 [Source:Xenbase;Acc:XB-GENE-1016830])

HSP 1 Score: 527.709 bits (1358), Expect = 0.000e+0
Identity = 271/533 (50.84%), Postives = 361/533 (67.73%), Query Frame = 2

Query:   98 FSISKPDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPE----DNACLRKDNKTRSNKTTNFVSERPYLLKSKKCH--CHCRSPLIIDSRDH---FNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDAIRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSY--TCPCRTKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLCCRKSLHHKVTCPTQLDKPLCKPETLSTKAL 1663
            F+  +P  +   C  I + MCKGIGYN TY+PN  NH + +EAG+E+ QF  LV I CS DL+ FLCSMY PICLP++   +P CRS+C  A+ GC+ +M +YGF WPE MNC++LPE    D  C+   N T +  T            S  C   C CR P +  +R+    +N++ TG + NC M C  PYF + +K+F+TFW+G+W+ +C IST  T+ TF ID  RF+YPERPIIFLS CYL +S+GY++R+ +GHE VAC  D I Y ++G   C++VFL IYFFGMASSIWWV+LT TWFLAAG+KWG+EAI  Y+  +H  AW IP ++SI +L +SSVDGDPV+GIC+VGN N  NL  FV+ PL+VYL  GT FLLAGF++L +IR  IK+ G +KTDKLEKLMIRI IF ++Y+VP   VV C IYE  +R+ WE+++  +CP   K+Y+P+Y+VFMLKYFM LVVG T+G WIW+ KTL+SW +   +  CCR S     +  ++  + L     LS+  L
Sbjct:   21 FAPVRPASKAIVCQEITVPMCKGIGYNHTYMPNQFNHDTQDEAGMEVHQFWPLVVIQCSLDLKFFLCSMYTPICLPDYRKPLPPCRSVCERAKAGCSPLMRKYGFAWPERMNCDRLPEHGDPDTLCMDY-NWTETTTTPPPTHPPKVKTPSSDCDGVCKCREPFLSITRESHPLYNRIKTGQVPNCAMPCFQPYFTQDEKTFATFWIGLWSILCFISTFTTVATFLIDMERFRYPERPIIFLSACYLFVSIGYIVRLIVGHENVACNKDHIHYETTGPALCTVVFLLIYFFGMASSIWWVILTFTWFLAAGMKWGNEAIASYSQYFHMAAWLIPSVKSIAVLALSSVDGDPVAGICFVGNQNLDNLRGFVLAPLVVYLFTGTMFLLAGFVSLFRIRSVIKQGG-TKTDKLEKLMIRIGIFSVLYTVPATIVVACYIYEQHYREHWEKAHNCSCPGDKKRYRPDYAVFMLKYFMCLVVGITSGVWIWSGKTLESWKRFTGR--CCRNSKPINASAYSEASRALTARTGLSSSTL 549

[Close]

BLAST of Frizzled-5 vs. Ensembl Xenopus
Match: fzd8 (frizzled class receptor 8 [Source:NCBI gene;Acc:100038274])

HSP 1 Score: 483.797 bits (1244), Expect = 1.441e-164
Identity = 255/518 (49.23%), Postives = 337/518 (65.06%), Query Frame = 2

Query:  131 TCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPE----DNACLRKDNKTRSN------------------KTTNFVSERPYLLKSKKCH--CHCRSPLI-IDSRDH--FNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDA------IRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTC----PCRTKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLC 1573
            +C  I + +CK IGYN TY+PN  NH + +EAG+E+ QF  LV I+CS DL+ FLCSMY PICL ++   +P CRS+C  AR GC  +M QYGF WP+ M C++LPE    D  C+   N+T                     K    V       ++  C   C CR+P++ + +  H  +N+V TG I NC M C +PYF   +++F+ FW+G+W+ +C  ST  T+ TF ID  RF+YPERPIIFLS CYLL+S GYL+R+  GHE VAC          I Y ++G   C++VFL IYFFGMASSIWWV+L+ TWFLAAG+KWG+EAI  Y+  +H  AW +P I+SI +L +SSVDGDPV+GIC+VGN N  NL  FV+ PL++YL +G+ FLLAGF++L +IR  IK+ G +KTDKLEKLMIRI IF ++Y+VP   VV C  YE   R  WE ++ C    P   +  +P+Y+VFMLKYFM LVVG T+G WIW+ KTL+SW + FC   C
Sbjct:   26 SCQEITVPLCKDIGYNYTYMPNQFNHDTQDEAGMEVHQFWPLVVIHCSPDLKFFLCSMYTPICLEDYKKPLPPCRSVCERARAGCAPLMRQYGFAWPDRMRCDRLPEQGNPDTLCMDYYNRTEQTTAAPSHPEPPKPPARSAPKGRTRVEPPRPRPRAPGCEPGCQCRAPMVPVTNERHPLYNRVRTGQIPNCAMPCHNPYFSPEERTFTEFWIGLWSVLCFASTFATVSTFLIDMERFKYPERPIIFLSACYLLVSAGYLVRLIAGHEKVACSRGELDLEHIIHYETTGPALCTLVFLLIYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYSQYFHLAAWLVPSIKSIAVLALSSVDGDPVAGICFVGNQNLDNLRGFVLAPLVIYLFIGSMFLLAGFVSLFRIRSVIKQGG-TKTDKLEKLMIRIGIFSVLYTVPATIVVACFFYEQHNRQGWEVAHNCNSCQPEVAQPRRPDYAVFMLKYFMCLVVGITSGVWIWSGKTLESW-RAFCTRCC 541

[Close]

BLAST of Frizzled-5 vs. Ensembl Xenopus
Match: bdh2 (3-hydroxybutyrate dehydrogenase 2 [Source:Xenbase;Acc:XB-GENE-985755])

HSP 1 Score: 392.889 bits (1008), Expect = 1.544e-129
Identity = 226/518 (43.63%), Postives = 309/518 (59.65%), Query Frame = 2

Query:  101 SISKPDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNA---CLRKDNKTRSNKTTNFVSERPYLLKSKKCHCHCRS----PLIIDSRDHFNKVVTGNISNCLMNCRSP------YFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACK---SDAIRYGSSGAVP--CSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSY---TC-----PCRTKKY---QPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKL 1567
             IS PD     C PI I +C  I YN T +PN L H + E+AGLE+ QF  LV++ CS +LR FLCSMYAP+C       IP CRSLC  AR+GC  +MN++GF+WPE + CE  P   A   C+ + N + ++ +       PYL  S   H H       P  +    +      G   +C   C         YF E +  F+  W+GIWA +C IST  T+LT+ +D  RF YPERPIIFLS CY +++V Y     L    V  +    D+ R  + G     C+I+F+ +YFFGMASSIWWV+L+ TWFLAAG+KWG EAI   +  +H  AW +P +++I IL M  VDGD +SG+CYVG  +  +L  FV+ PL VYL +GT FLLAGF++L +IR  +K  G +KT+KLEKLM+RI +F ++Y+VP   V+ C  YE  FRD WE+++   TC     PC    +    P+++VFM+KY M ++VG T+ FWIW+ KTL SW + + +L
Sbjct:   27 GISVPDH--GFCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCT-VLEQAIPPCRSLCERARQGCEALMNKFGFQWPERLRCENFPVHGAGEICVGQ-NTSDNSPSGPTARPTPYLPDSITFHPHPNRDFTCPRQLKVPPYLGYRFLGE-KDCGAPCEPGKANGLMYFKEEEVRFARLWVGIWAILCGISTLFTVLTYLVDMRRFSYPERPIIFLSGCYFMVAVAYTAGFLLEERGVCVERFSEDSYRTVAQGTKKEGCTILFMILYFFGMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQVDGDILSGVCYVGINSVDSLRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDG-TKTEKLEKLMVRIGVFSVMYTVPATIVLACYFYEQAFRDTWEKTWLVQTCKGFAVPCPNYNFAPMSPDFTVFMIKYLMTMIVGITSSFWIWSGKTLQSWRRFYHRL 538

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BLAST of Frizzled-5 vs. Ensembl Xenopus
Match: ntrk1 (neurotrophic receptor tyrosine kinase 1 [Source:Xenbase;Acc:XB-GENE-923001])

HSP 1 Score: 384.8 bits (987), Expect = 2.496e-126
Identity = 222/539 (41.19%), Postives = 311/539 (57.70%), Query Frame = 2

Query:   74 LFRICGQSFS-------ISKPDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNA---CLRKDNKTRSNKTTNFVSERP--------YLLKSKKCHCHCRSPLIIDSRDHFNKVVTGNISNCLMNCRSP------YFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDAIRYGSSGAVP------CSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYT----------CPCR-TKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKL 1567
            LF +C  SF+       IS P+     C PI I +C  I YN T +PN L H + E+AGLE+ QF  LV++ CS +LR FLCSMYAP+C       IP CRS+C  AR GC  +MN++GF+WPE + CE  P   A   C+ +++      T    S           Y       HC    P ++    + N    G   +C   C         +F + +  F+  W+ IW+ +C  ST  T+ T+ +D  RF+YPERPIIFLS CY ++SV Y+    LG + V C  +    G    V       C+I+F+ +YFF MASSIWWV+L+ TWFLAAG+KWG EAI   +  +H  AW +P +++I IL M  +DGD +SG+C+VG  N   L  FV+ PL VYL +GT FLLAGF++L +IR  +K  G +KT+KLE+LM+RI +F ++Y+VP   V+ C  YE  FR+ WE+S+           CP + T +  P+++V+M+KY M L+VG T+GFWIW+ KTL SW K + +L
Sbjct:   15 LFALCLLSFAQLHGEKGISVPE--HGFCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSSELRFFLCSMYAPVCTV-LEQAIPPCRSICERARHGCEALMNKFGFQWPERLRCENFPRHGAEQICVGQNHSEDGGPTLLTTSPPHHGTPGPPIYATLDHPFHC----PRVLKVPSYLNYRFLGE-KDCAAPCEPSKNDGFMFFSQDEIRFARVWILIWSVLCCASTFFTVTTYLVDMQRFRYPERPIIFLSGCYTMVSVAYIAGFVLG-DKVVCNENFSEDGYKTVVQGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQIDGDLLSGVCFVGLNNIDPLRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDG-TKTEKLERLMVRIGVFSVLYTVPATIVIACYFYEQAFREHWERSWVSQNCKSLAIPCPLQYTPRMTPDFTVYMIKYLMTLIVGITSGFWIWSGKTLHSWRKFYTRL 543

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BLAST of Frizzled-5 vs. Ensembl Xenopus
Match: FZD9 (frizzled class receptor 9 [Source:NCBI gene;Acc:100487936])

HSP 1 Score: 380.948 bits (977), Expect = 1.211e-124
Identity = 218/512 (42.58%), Postives = 299/512 (58.40%), Query Frame = 2

Query:  122 RPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNA----CLRK-DNKTRSNKTTNFVSERPYLLKSKKCHCHCRSPLIIDSR----DHFNKVVTGNISNCLMNC---RSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDA-----IRYG--SSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLW------EQSYTCP------CRTKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCK 1564
            R + C PI+I MC+GIGYN+T +PN + H S EEA  ++Q+F  LVE  C   LR FLCS+YAP+C       IPAC+ +C +AR+ C  +M  + + WPE ++C++LP  N     C+   +N T  +  TN     P   +  +      S + I SR    D F  V    +  C   C      Y+   DK F+  W+  W+ +C IST+ T+ TF +   RFQYPE+PIIFLS+CY + S  +LIR A G  ++AC  +      IR G  SSG   C++VFL +Y+FGMASS+WWVVLT TWFLAA  KWG EAI  +   +H  AW IP I++IIILTM  V GD ++G+CYVG  +   L  FV++PL  YL+ GT FLL GF+AL  IR+ +K  G + T+KLEKLM++I +F I+Y+VP   ++ C  YE +    W      E   T P      C      P  +VFMLK FM+L VG T+G W+W+ KTL +W  + C+
Sbjct:   24 REAKCEPIQIPMCQGIGYNMTRMPNYVGHESQEEAAAKLQEFAPLVEYGCHIHLRFFLCSLYAPMCTEQVSTSIPACKPMCEAARQKCAPIMESFQYVWPESLDCDRLPSKNDPHALCMEAPENATNGDPPTNGHGMLPVAPRPPR---PSGSGIGISSRCANPDKFMYVERSGV--CAPRCIPGVDVYWSSGDKDFALVWMAAWSGLCFISTAFTVFTFLLHPQRFQYPEKPIIFLSMCYNVYSTAFLIRAAAGAPSIACDREGGAPYLIREGLESSG---CTLVFLILYYFGMASSLWWVVLTLTWFLAASKKWGHEAIESHGSYFHLAAWGIPAIKTIIILTMRKVGGDELTGLCYVGGSDPSALTGFVLVPLSCYLVTGTSFLLTGFVALFHIRRVMKTGG-TNTEKLEKLMVKIGVFSILYTVPATCIIVCCFYERLNLAHWDSRAREESCRTVPGSARPDCNLPHSIPSVAVFMLKIFMSLAVGITSGVWVWSSKTLQAWQGILCQ 526

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BLAST of Frizzled-5 vs. Ensembl Mouse
Match: Fzd5 (frizzled class receptor 5 [Source:MGI Symbol;Acc:MGI:108571])

HSP 1 Score: 499.204 bits (1284), Expect = 1.232e-170
Identity = 263/534 (49.25%), Postives = 353/534 (66.10%), Query Frame = 2

Query:   80 RICGQSFSISKPDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLP-----EDNACLRKDNKTRSNKTTNFVSERPYLL-------KSKKCH------CHCRSPLII---DSRDHFNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDA--IRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPC-----RTKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLCCRKSLHHK 1597
            ++ G++ + SK  +    C  I + MC+GIGYNLT++PN  NH + +EAGLE+ QF  LVEI+CS DLR FLCSMY PICLP++   +P CRS+C  A+ GC+ +M QYGF WPE M+C++LP      +  C+  +    +  +      +P L           +C       C CR P +    +S   +NKV TG + NC + C  P F   +++F+TFW+G+W+ +C ISTS T+ TF ID  RF+YPERPIIFLS CYL +S+G+L+R+ +GH +VAC  +   I Y ++G   C++VFL +YFFGMASSIWWV+L+ TWFLAAG+KWG+EAI  YA  +H  AW IP ++SI  L +SSVDGDPV+GICYVGN N  +L  FV+ PL++YLLVGT FLLAGF++L +IR  IK+ G +KTDKLEKLMIRI IF ++Y+VP   VV C +YE  +R+ WE + TC C        + +PEY V MLKYFM LVVG T+G WIW+ KTL+SW + F    CC     HK
Sbjct:   19 QLVGRAAAASKAPV----CQEITVPMCRGIGYNLTHMPNQFNHDTQDEAGLEVHQFWPLVEIHCSPDLRFFLCSMYTPICLPDYHKPLPPCRSVCERAKAGCSPLMRQYGFAWPERMSCDRLPVLGGDAEVLCMDYNRSEATTASPKSFPAKPTLPGPPGAPSSGGECPSGGPSVCTCREPFVPILKESHPLYNKVRTGQVPNCAVPCYQPSFSPDERTFATFWIGLWSVLCFISTSTTVATFLIDMERFRYPERPIIFLSACYLCVSLGFLVRLVVGHASVACSREHSHIHYETTGPALCTVVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYAQYFHLAAWLIPSVKSITALALSSVDGDPVAGICYVGNQNLNSLRGFVLGPLVLYLLVGTLFLLAGFVSLFRIRSVIKQGG-TKTDKLEKLMIRIGIFTLLYTVPASIVVACYLYEQHYRESWEAALTCACPGPDAGQPRAKPEYWVLMLKYFMCLVVGITSGVWIWSGKTLESWRR-FTSRCCCSSRRGHK 546

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Query:   80 RICGQSFSISKPDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLP-----EDNACLRKDNKTRSNKTTNFVSERPYLL-------KSKKCH------CHCRSPLII---DSRDHFNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDA--IRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPC-----RTKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLCCRKSLHHK 1597
            ++ G++ + SK  +    C  I + MC+GIGYNLT++PN  NH + +EAGLE+ QF  LVEI+CS DLR FLCSMY PICLP++   +P CRS+C  A+ GC+ +M QYGF WPE M+C++LP      +  C+  +    +  +      +P L           +C       C CR P +    +S   +NKV TG + NC + C  P F   +++F+TFW+G+W+ +C ISTS T+ TF ID  RF+YPERPIIFLS CYL +S+G+L+R+ +GH +VAC  +   I Y ++G   C++VFL +YFFGMASSIWWV+L+ TWFLAAG+KWG+EAI  YA  +H  AW IP ++SI  L +SSVDGDPV+GICYVGN N  +L  FV+ PL++YLLVGT FLLAGF++L +IR  IK+ G +KTDKLEKLMIRI IF ++Y+VP   VV C +YE  +R+ WE + TC C        + +PEY V MLKYFM LVVG T+G WIW+ KTL+SW + F    CC     HK
Sbjct:   19 QLVGRAAAASKAPV----CQEITVPMCRGIGYNLTHMPNQFNHDTQDEAGLEVHQFWPLVEIHCSPDLRFFLCSMYTPICLPDYHKPLPPCRSVCERAKAGCSPLMRQYGFAWPERMSCDRLPVLGGDAEVLCMDYNRSEATTASPKSFPAKPTLPGPPGAPSSGGECPSGGPSVCTCREPFVPILKESHPLYNKVRTGQVPNCAVPCYQPSFSPDERTFATFWIGLWSVLCFISTSTTVATFLIDMERFRYPERPIIFLSACYLCVSLGFLVRLVVGHASVACSREHSHIHYETTGPALCTVVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYAQYFHLAAWLIPSVKSITALALSSVDGDPVAGICYVGNQNLNSLRGFVLGPLVLYLLVGTLFLLAGFVSLFRIRSVIKQGG-TKTDKLEKLMIRIGIFTLLYTVPASIVVACYLYEQHYRESWEAALTCACPGPDAGQPRAKPEYWVLMLKYFMCLVVGITSGVWIWSGKTLESWRR-FTSRCCCSSRRGHK 546

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BLAST of Frizzled-5 vs. Ensembl Mouse
Match: Fzd8 (frizzled class receptor 8 [Source:MGI Symbol;Acc:MGI:108460])

HSP 1 Score: 469.929 bits (1208), Expect = 1.027e-157
Identity = 251/587 (42.76%), Postives = 345/587 (58.77%), Query Frame = 2

Query:  131 TCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPE----DNACL----------------------------------------RKDNKTRSNKTTNFVSE---------RPYLLKSKKCH--CHCRSPLI-IDSRDH--FNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACK------------------------------------------SDAIRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEK-GESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPC-----RTKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLC 1573
             C  I + +CKGIGYN TY+PN  NH + +EAGLE+ QF  LVEI CS DL+ FLCSMY PICL ++   +P CRS+C  A+ GC  +M QYGF WP+ M C++LPE    D  C+                                        R  ++  S++ +   +          RP    +  C   C CR+P++ + S  H  +N+V TG I+NC + C +P+F + +++F+ FW+G+W+ +C +ST  T+ TF ID  RF+YPERPIIFLS CYL +SVGYL+R+  GHE VAC                                              +RY ++G   C++VFL +YFFGMASSIWWV+L+ TWFLAAG+KWG+EAI  Y+  +H  AW +P ++SI +L +SSVDGDPV+GICYVGN +  NL  FV+ PL++YL +GT FLLAGF++L +IR  IK++ G +KT KLEKLMIR+ +F ++Y+VP   VV C  YE   R  WE ++ CPC       +  +P+Y+VFMLKYFM LVVG T+G W+W+ KTL+SW +  C   C
Sbjct:   34 ACQEITVPLCKGIGYNYTYMPNQFNHDTQDEAGLEVHQFWPLVEIQCSPDLKFFLCSMYTPICLEDYKKPLPPCRSVCERAKAGCAPLMRQYGFAWPDRMRCDRLPEQGNPDTLCMDYNRTDLTTAAPSPPRRLPPPPPPGEQPPSGSGHSRPPGARPPHRGGSSRGSGDAAAAPPSRGGKARPPGGGAAPCEPGCQCRAPMVSVSSERHPLYNRVKTGQIANCALPCHNPFFSQDERAFTVFWIGLWSVLCFVSTFATVSTFLIDMERFKYPERPIIFLSACYLFVSVGYLVRLVAGHEKVACSGGAPGAGGAGGAGGAAAAGAGAAGAGASSPGARGEYEELGAVEQHVRYETTGPALCTVVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYSQYFHLAAWLVPSVKSIAVLALSSVDGDPVAGICYVGNQSLDNLRGFVLAPLVIYLFIGTMFLLAGFVSLFRIRSVIKQQGGPTKTHKLEKLMIRLGLFTVLYTVPAAVVVACLFYEQHNRPRWEATHNCPCLRDLQPDQARRPDYAVFMLKYFMCLVVGITSGVWVWSGKTLESW-RALCTRCC 619

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BLAST of Frizzled-5 vs. Ensembl Mouse
Match: Fzd10 (frizzled class receptor 10 [Source:MGI Symbol;Acc:MGI:2136761])

HSP 1 Score: 395.586 bits (1015), Expect = 3.953e-130
Identity = 232/548 (42.34%), Postives = 322/548 (58.76%), Query Frame = 2

Query:   68 WVLFRI-CGQSFSISKPDL-RPS--TCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNA----CLRKDNKTRSNKTTNFVSERPYLLKSKKCHCHCRSPLI--------IDSRDHFNKVVTGNISNCLMNCRSP---YFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDA-----IRYG--SSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWE------------QSYTCPCRTKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLCCRKSLHHK 1597
            W++ ++  G   +IS  DL RP    C P+EI MCK IGYN T +PN + H +  EA +++ +F  LVE  C   LR FLCS+YAP+C       IPACR +C  AR  C+ +M Q+ F+WP+ ++C KLP  N     C+   N   S++ +      P L + ++ H     PL          D+   F+ V      +C   C      Y+   DK F+  WL IW+ +C  S++ T+LTF ID SRF+YPERPIIFLS+CY + SVGY+IR+  G E++AC  D+     I+ G  S+G   C++VFL +Y+FGMASS+WWVVLT TWFLAAG KWG EAI   +  +H  AW IP +++I+IL M  V GD ++G+CYVG+++   L  FV++PL  YL++GT F+L+GF+AL  IR+ +K  GE+ TDKLEKLM+RI +F ++Y+VP   V+ C  YE +  D W+            Q+ T  C      P   VFM+K  M LVVG T+G W+WT KTL SW  V      C + L  K
Sbjct:    9 WLVLQVMIGSCTAISSMDLERPGDGKCQPVEIPMCKDIGYNTTRMPNLMGHENQREAAIQLHEFAPLVEYGCHSHLRFFLCSLYAPMCTEQVSTPIPACRVMCEQARLKCSPIMEQFKFRWPDSLDCSKLPNKNDPNYLCMEAPNNG-SDEPSRGSGMFPPLFRPQRPHSAQEHPLKDGGPGRAGCDNPGKFHHVEKSE--SCAPLCTPGVDVYWSRDDKRFAVVWLAIWSVLCFFSSAFTVLTFLIDPSRFRYPERPIIFLSMCYCVYSVGYIIRLFAGAESIACDRDSGQLYVIQEGLESTG---CTLVFLVLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEANSSYFHLAAWAIPAVKTILILVMRRVAGDELTGVCYVGSMDVNALTGFVLVPLACYLVIGTSFILSGFVALFHIRRVMKTGGEN-TDKLEKLMVRIGVFSLLYTVPATCVIACYFYERLNMDYWKMLATQHKCKMNNQTKTPDCLMTTSIPAVEVFMVKVSMLLVVGITSGVWVWTSKTLQSWQHV------CSRGLKRK 543

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BLAST of Frizzled-5 vs. Ensembl Mouse
Match: Fzd7 (frizzled class receptor 7 [Source:MGI Symbol;Acc:MGI:108570])

HSP 1 Score: 385.956 bits (990), Expect = 1.436e-126
Identity = 223/533 (41.84%), Postives = 309/533 (57.97%), Query Frame = 2

Query:  101 SISKPDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNA---CLRKDNKTR---------SNKTTNFVSERPYLLKSKK-----------CHCHCRSP-----LIIDSRDHFNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACK---SDAIRYGSSGAVP--CSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWE--------QSYTCPCRTKKY---QPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKL 1567
             IS PD     C PI I +C  I YN T +PN L H + E+AGLE+ QF  LV++ CS +LR FLCSMYAP+C       IP CRSLC  AR+GC  +MN++GF+WPE + CE  P   A   C+ ++             +  T  ++ + P+   S             C    + P       +  RD       G  +N LM     YF E ++ F+  W+G+W+ +C  ST  T+LT+ +D  RF YPERPIIFLS CY +++V ++    L   AV  +    D  R  + G     C+I+F+ +YFFGMASSIWWV+L+ TWFLAAG+KWG EAI   +  +H  AW +P +++I IL M  VDGD +SG+CYVG  +   L  FV+ PL VYL +GT FLLAGF++L +IR  +K  G +KT+KLEKLM+RI +F ++Y+VP   V+ C  YE  FR+ WE        +SY  PC    +    P+++VFM+KY M ++VG T GFWIW+ KTL SW + + +L
Sbjct:   40 GISVPDH--GFCQPISIPLCTDIAYNQTILPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCT-VLDQAIPPCRSLCERARQGCEALMNKFGFQWPERLRCENFPVHGAGEICVGQNTSDGSGGAGGSPTAYPTAPYLPDPPFTAMSPSDGRGRLSFPFSCPRQLKVPPYLGYRFLGERDCGAPCEPGR-ANGLM-----YFKEEERRFARLWVGVWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYFMVAVAHVAGFLLEDRAVCVERFSDDGYRTVAQGTKKEGCTILFMVLYFFGMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQVDGDLLSGVCYVGLSSVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDG-TKTEKLEKLMVRIGVFSVLYTVPATIVLACYFYEQAFREHWERTWLLQTCKSYAVPCPPGHFSPMSPDFTVFMIKYLMTMIVGITTGFWIWSGKTLQSWRRFYHRL 562

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BLAST of Frizzled-5 vs. UniProt/SwissProt
Match: sp|P58421|FZD5_XENLA (Frizzled-5 OS=Xenopus laevis OX=8355 GN=fzd5 PE=2 SV=1)

HSP 1 Score: 516.924 bits (1330), Expect = 5.023e-177
Identity = 269/533 (50.47%), Postives = 357/533 (66.98%), Query Frame = 2

Query:   98 FSISKPDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPE----DNACLRKDNKTRSNKTTNFVSERPYLLKSKKCH--CHCRSPLIIDSRDH---FNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDAIRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSY--TCPCRTKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLCCRKSLHHKVTCPTQLDKPLCKPETLSTKAL 1663
            F+ ++   +   C  I + MCKGIGYN TY+PN  NH + +EAG+E+ QF  LV I CS DL+ FLCSMY PICLP++   +P CRS+C  A+ GC+ +M +YGF WPE MNC++LPE    D  C+   N T +  T            +  C   C CR P +  +R+    +N++ TG + NC M C  PYF + +K F TFW+G+W+ +C IST  T+ TF ID  RF+YPERPIIFLS CYL +S+GY++R+ +GHE VAC  D I Y ++G   C+IVFL IYFFGMASSIWWV+LT TWFLAAG+KWG+EAI  Y+  +H  AW IP ++SI +L +SSVDGDPV+GICYVGN N  NL  FV+ PL+VYL  GT FLLAGF++L +IR  IK+ G +KTDKLEKLMIRI IF ++Y+VP   VV C IYE  +R+ WE+++  +CP   ++Y+P+Y+VFMLKY M LVVG T+G WIW+ KTL+SW +   +  CCR S     +  ++  + L     LS   L
Sbjct:   21 FAPAQAASKAIVCQEITVPMCKGIGYNHTYMPNQFNHDTQDEAGMEVHQFWPLVVIQCSLDLKFFLCSMYTPICLPDYRKPLPPCRSVCERAKAGCSPLMRKYGFAWPERMNCDRLPEHGDPDTLCMYY-NWTETTTTLPPTHPPKVKTPTSDCDGVCKCREPFVSITRESHPLYNRIKTGQVPNCAMPCFQPYFTQDEKMFVTFWIGLWSILCFISTFTTVATFLIDMERFRYPERPIIFLSACYLFVSIGYVVRLIVGHENVACNKDHIHYETTGPALCTIVFLLIYFFGMASSIWWVILTFTWFLAAGMKWGNEAIASYSQYFHMAAWLIPSVKSIAVLALSSVDGDPVAGICYVGNQNLDNLRGFVLAPLVVYLFSGTMFLLAGFVSLFRIRSVIKQGG-TKTDKLEKLMIRIGIFSVLYTVPATIVVACYIYEQHYREHWEKTHNCSCPGDKQRYRPDYAVFMLKYLMCLVVGITSGVWIWSGKTLESWKRFTGR--CCRNSKPINASAYSEASRALTPRTGLSNLTL 549

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BLAST of Frizzled-5 vs. UniProt/SwissProt
Match: sp|Q13467|FZD5_HUMAN (Frizzled-5 OS=Homo sapiens OX=9606 GN=FZD5 PE=1 SV=2)

HSP 1 Score: 503.056 bits (1294), Expect = 3.627e-171
Identity = 271/537 (50.47%), Postives = 356/537 (66.29%), Query Frame = 2

Query:   80 RICGQSFSISKPDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLP---EDNACLRKDNKTRSNKTTNFVSERPYLLK------------SKKCH------CHCRSPLII---DSRDHFNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVAC--KSDAIRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPC-----RTKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLCCRKSLHHK 1597
            ++ G++ + SK  +    C  I + MC+GIGYNLT++PN  NH + +EAGLE+ QF  LVEI CS DLR FLCSMY PICLP++   +P CRS+C  A+ GC+ +M QYGF WPE M+C++LP    D   L  D   RS  TT     RP+  K              +C       C CR P +    +S   +NKV TG + NC + C  P F   +++F+TFW+G+W+ +C ISTS T+ TF ID  RF+YPERPIIFLS CYL +S+G+L+R+ +GH +VAC  + + I Y ++G   C+IVFL +YFFGMASSIWWV+L+ TWFLAAG+KWG+EAI  YA  +H  AW IP ++SI  L +SSVDGDPV+GICYVGN N  +L  FV+ PL++YLLVGT FLLAGF++L +IR  IK+ G +KTDKLEKLMIRI IF ++Y+VP   VV C +YE  +R+ WE + TC C        + +PEY V MLKYFM LVVG T+G WIW+ KT++SW + F    CCR    HK
Sbjct:   19 QLVGRAAAASKAPV----CQEITVPMCRGIGYNLTHMPNQFNHDTQDEAGLEVHQFWPLVEIQCSPDLRFFLCSMYTPICLPDYHKPLPPCRSVCERAKAGCSPLMRQYGFAWPERMSCDRLPVLGRDAEVLCMDYN-RSEATT--APPRPFPAKPTLPGPPGAPASGGECPAGGPFVCKCREPFVPILKESHPLYNKVRTGQVPNCAVPCYQPSFSADERTFATFWIGLWSVLCFISTSTTVATFLIDMERFRYPERPIIFLSACYLCVSLGFLVRLVVGHASVACSREHNHIHYETTGPALCTIVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYAQYFHLAAWLIPSVKSITALALSSVDGDPVAGICYVGNQNLNSLRGFVLGPLVLYLLVGTLFLLAGFVSLFRIRSVIKQGG-TKTDKLEKLMIRIGIFTLLYTVPASIVVACYLYEQHYRESWEAALTCACPGHDTGQPRAKPEYWVLMLKYFMCLVVGITSGVWIWSGKTVESWRR-FTSRCCCRPRRGHK 546

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BLAST of Frizzled-5 vs. UniProt/SwissProt
Match: sp|Q8CHL0|FZD5_RAT (Frizzled-5 OS=Rattus norvegicus OX=10116 GN=Fzd5 PE=2 SV=1)

HSP 1 Score: 499.59 bits (1285), Expect = 8.249e-170
Identity = 262/534 (49.06%), Postives = 353/534 (66.10%), Query Frame = 2

Query:   80 RICGQSFSISKPDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLP-----EDNACLRKDNKTRSNKTTNFVSERPYLL-------KSKKCH------CHCRSPLII---DSRDHFNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDA--IRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPC-----RTKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLCCRKSLHHK 1597
            ++ G++ + SK  +    C  I + MC+GIGYNLT++PN  NH + +EAGLE+ QF  LVEI+CS DLR FLCSMY PICLP++   +P CRS+C  A+ GC+ +M QYGF WPE M+C++LP      +  C+  +    +  +      +P L           +C       C CR P +    +S   +NKV TG + NC + C  P F   +++F+TFW+G+W+ +C ISTS T+ TF ID  RF+YPERPIIFLS CYL +S+G+L+R+ +GH +VAC  +   I Y ++G   C++VFL +YFFGMASSIWWV+L+ TWFLAAG+KWG+EAI  YA  +H  AW IP ++SI  L +SSVDGDPV+G+CYVGN N  +L  FV+ PL++YLLVGT FLLAGF++L +IR  IK+ G +KTDKLEKLMIRI IF ++Y+VP   VV C +YE  +R+ WE + TC C        + +PEY V MLKYFM LVVG T+G WIW+ KTL+SW + F    CC     HK
Sbjct:   19 QLVGRAAAASKAPV----CQEITVPMCRGIGYNLTHMPNQFNHDTQDEAGLEVHQFWPLVEIHCSPDLRFFLCSMYTPICLPDYHKPLPPCRSVCERAKAGCSPLMRQYGFAWPERMSCDRLPVLGGDAEVLCMDYNRSEATTASPKSFPAKPTLPGPPGAPSSGGECPSGGPSVCTCREPFVPILKESHPLYNKVRTGQVPNCAVPCYQPSFSPDERTFATFWIGLWSVLCFISTSTTVATFLIDMERFRYPERPIIFLSACYLCVSLGFLVRLVVGHASVACSREHSHIHYETTGPALCTVVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYAQYFHLAAWLIPSVKSITALALSSVDGDPVAGVCYVGNQNLNSLRGFVLGPLVLYLLVGTLFLLAGFVSLFRIRSVIKQGG-TKTDKLEKLMIRIGIFTLLYTVPASIVVACYLYEQHYRESWEAALTCACPGSDAGQPRAKPEYWVLMLKYFMCLVVGITSGVWIWSGKTLESWRR-FTSRCCCSSRRGHK 546

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BLAST of Frizzled-5 vs. UniProt/SwissProt
Match: sp|Q9EQD0|FZD5_MOUSE (Frizzled-5 OS=Mus musculus OX=10090 GN=Fzd5 PE=1 SV=3)

HSP 1 Score: 499.204 bits (1284), Expect = 8.615e-170
Identity = 263/534 (49.25%), Postives = 353/534 (66.10%), Query Frame = 2

Query:   80 RICGQSFSISKPDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLP-----EDNACLRKDNKTRSNKTTNFVSERPYLL-------KSKKCH------CHCRSPLII---DSRDHFNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDA--IRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPC-----RTKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLCCRKSLHHK 1597
            ++ G++ + SK  +    C  I + MC+GIGYNLT++PN  NH + +EAGLE+ QF  LVEI+CS DLR FLCSMY PICLP++   +P CRS+C  A+ GC+ +M QYGF WPE M+C++LP      +  C+  +    +  +      +P L           +C       C CR P +    +S   +NKV TG + NC + C  P F   +++F+TFW+G+W+ +C ISTS T+ TF ID  RF+YPERPIIFLS CYL +S+G+L+R+ +GH +VAC  +   I Y ++G   C++VFL +YFFGMASSIWWV+L+ TWFLAAG+KWG+EAI  YA  +H  AW IP ++SI  L +SSVDGDPV+GICYVGN N  +L  FV+ PL++YLLVGT FLLAGF++L +IR  IK+ G +KTDKLEKLMIRI IF ++Y+VP   VV C +YE  +R+ WE + TC C        + +PEY V MLKYFM LVVG T+G WIW+ KTL+SW + F    CC     HK
Sbjct:   19 QLVGRAAAASKAPV----CQEITVPMCRGIGYNLTHMPNQFNHDTQDEAGLEVHQFWPLVEIHCSPDLRFFLCSMYTPICLPDYHKPLPPCRSVCERAKAGCSPLMRQYGFAWPERMSCDRLPVLGGDAEVLCMDYNRSEATTASPKSFPAKPTLPGPPGAPSSGGECPSGGPSVCTCREPFVPILKESHPLYNKVRTGQVPNCAVPCYQPSFSPDERTFATFWIGLWSVLCFISTSTTVATFLIDMERFRYPERPIIFLSACYLCVSLGFLVRLVVGHASVACSREHSHIHYETTGPALCTVVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYAQYFHLAAWLIPSVKSITALALSSVDGDPVAGICYVGNQNLNSLRGFVLGPLVLYLLVGTLFLLAGFVSLFRIRSVIKQGG-TKTDKLEKLMIRIGIFTLLYTVPASIVVACYLYEQHYRESWEAALTCACPGPDAGQPRAKPEYWVLMLKYFMCLVVGITSGVWIWSGKTLESWRR-FTSRCCCSSRRGHK 546

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BLAST of Frizzled-5 vs. UniProt/SwissProt
Match: sp|O93274|FZD8_XENLA (Frizzled-8 OS=Xenopus laevis OX=8355 GN=fzd8 PE=1 SV=1)

HSP 1 Score: 488.804 bits (1257), Expect = 1.010e-165
Identity = 255/518 (49.23%), Postives = 337/518 (65.06%), Query Frame = 2

Query:  131 TCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPE----DNACLRKDNKTRSN------------------KTTNFVSERPYLLKSKKCH--CHCRSPLIIDSRDH---FNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDA------IRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTC----PCRTKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLC 1573
            +C  I + +CK IGYN TY+PN  NH + +EAG+E+ QF  LV I+CS DL+ FLCSMY PICL ++   +P CRS+C  AR GC  +M QYGF WP+ M C++LPE    D  C+   N+T                     K    V       ++  C   C CR+P++  S +    +N+V TG I NC M C +P+F   +++F+ FW+G+W+ +C  ST  T+ TF ID  RF+YPERPIIFLS CYLL+S GYLIR+  GHE VAC          I Y ++G   C++VFL IYFFGMASSIWWV+L+ TWFLAAG+KWG+EAI  Y+  +H  AW +P I+SI +L +SSVDGDPV+GIC+VGN N  NL  FV+ PL++YL +G+ FLLAGF++L +IR  IK+ G +KTDKLEKLMIRI IF ++Y+VP   VV C  YE   R  WE ++ C    P   + ++P+Y+VFMLKYFM LVVG T+G WIW+ KTL+SW + FC   C
Sbjct:   27 SCQEITVPLCKDIGYNYTYMPNQFNHDTQDEAGMEVHQFWPLVVIHCSPDLKFFLCSMYTPICLEDYKKPLPPCRSVCERARAGCAPLMRQYGFAWPDRMRCDRLPEQGNPDTLCMDYYNRTEQTTAAPSHPEPPKPPARSVPKGRTRVEPPRSRSRATGCESGCQCRAPMVQVSNERHPLYNRVRTGQIPNCAMPCHNPFFSPEERTFTEFWIGLWSVLCFASTFATVSTFLIDMERFKYPERPIIFLSACYLLVSTGYLIRLIAGHEKVACSRGELDLEHIIHYETTGPALCTLVFLLIYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYSQYFHLAAWLVPSIKSIAVLALSSVDGDPVAGICFVGNQNLDNLRGFVLAPLVIYLFIGSMFLLAGFVSLFRIRSVIKQGG-TKTDKLEKLMIRIGIFSVLYTVPATIVVACFFYEQHNRQGWEVAHNCNSCQPEMAQPHRPDYAVFMLKYFMCLVVGITSGVWIWSGKTLESW-RAFCTRCC 542

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BLAST of Frizzled-5 vs. TrEMBL
Match: T1E0Z7 (Fzd-5/8-1 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 1176.77 bits (3043), Expect = 0.000e+0
Identity = 589/590 (99.83%), Postives = 590/590 (100.00%), Query Frame = 2

Query:   32 MTIAIGISLLFSWVLFRICGQSFSISKPDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNACLRKDNKTRSNKTTNFVSERPYLLKSKKCHCHCRSPLIIDSRDHFNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDAIRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPCRTKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLCCRKSLHHKVTCPTQLDKPLCKPETLSTKALLYSLNSSYNVNDRQILSASNMIRSGITLSNSPDSETLTKLISLTHV 1801
            MTIAIGISLLFSWVLFRICGQSFSISKPDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNACLRKDNKTRSNKTTNFVSERPYLLKSKKCHCHCRSPLIIDSRDHFNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDAIRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYLLVGTGFLLAGFLALMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPCRTKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLCCRKSLH+KVTCPTQLDKPLCKPETLSTKALLYSLNSSYNVNDRQILSASNMIRSGITLSNSPDSETLTKLISLTHV
Sbjct:    1 MTIAIGISLLFSWVLFRICGQSFSISKPDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNACLRKDNKTRSNKTTNFVSERPYLLKSKKCHCHCRSPLIIDSRDHFNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDAIRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYLLVGTGFLLAGFLALMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPCRTKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLCCRKSLHYKVTCPTQLDKPLCKPETLSTKALLYSLNSSYNVNDRQILSASNMIRSGITLSNSPDSETLTKLISLTHV 590

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BLAST of Frizzled-5 vs. TrEMBL
Match: T1DF88 (Fzd-5/8-1 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1)

HSP 1 Score: 830.861 bits (2145), Expect = 0.000e+0
Identity = 398/565 (70.44%), Postives = 480/565 (84.96%), Query Frame = 2

Query:  110 KPDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNACLRKDNKTRSNKTTNFVSERPYLLKSKKCHCHCRSPLIIDSRDHFNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDAIRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPCRTKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLCCRKSLHHKVTCP-TQLDKPLCKPETLSTKALLYSLNSSYNVNDRQILSASNMIRSGITLSNSPDSETLTKLISLTHV 1801
            K + RP  C+PIE+SMCK IGYNLTY+PNDLNH S EEAGLE+ QF  LVEINCSEDLRLF+CSMYAPICLPNWPNR+PACRS+CISAR+GC  VM QYGFKWPE MNC+ LPEDNACLRK N+T +NK +       Y L  KKC CHCR+PLI D+RD++NK++TG ++NCLM+CR+PYF +FDK+F TFW+G+WAC+CI+ST++T+ TF ID+SRFQYPERPIIFLS CYLLM++GY+IRV LGHEA+ACK ++IRYG +G VPCSIVFL +YFFGMASSIWWV+LTATWFLAAGLKW SEAI MY+D+YHFFAWFIPG QSI +LTM+SVDGDP+SGIC+VGN NK+NLL FVIIPL+VYLL+G+GFLLAGFL+LMKIRKTIKEKGESKTDKLE LM+RI IFGIVYSVP +TV+ C +YE ++RD WE++YTCPC  KK+ PEYSVFMLKYFM L+VGTT+GFW+WT KTLDSW+K+ C+  C ++  H ++T      D P  KPETLSTK LL  +NSSYN++   I S+S+MI+SGIT+SN+ +SE L+KLI LTHV
Sbjct:   26 KVEPRPPKCVPIEMSMCKDIGYNLTYLPNDLNHGSQEEAGLEVSQFFPLVEINCSEDLRLFICSMYAPICLPNWPNRVPACRSVCISARDGCITVMRQYGFKWPERMNCDTLPEDNACLRKGNET-NNKMS-------YSLIPKKCKCHCRAPLIKDTRDYYNKIITGGVNNCLMSCRAPYFTDFDKNFPTFWIGLWACLCIVSTTITMATFFIDRSRFQYPERPIIFLSFCYLLMAIGYIIRVGLGHEAIACKGESIRYGLTGTVPCSIVFLLVYFFGMASSIWWVILTATWFLAAGLKWSSEAITMYSDVYHFFAWFIPGFQSIFVLTMTSVDGDPISGICFVGNTNKFNLLVFVIIPLLVYLLIGSGFLLAGFLSLMKIRKTIKEKGESKTDKLENLMLRIGIFGIVYSVPAITVILCCVYELLYRDKWEKTYTCPCEQKKFYPEYSVFMLKYFMTLIVGTTSGFWVWTSKTLDSWAKIICRSCCEKEHSHDQMTIKLNNADNPKGKPETLSTKTLLECMNSSYNMSGHPIRSSSSMIKSGITMSNTTESEILSKLIPLTHV 582

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BLAST of Frizzled-5 vs. TrEMBL
Match: T1DBJ2 (Fzd-5/8-4 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 620.928 bits (1600), Expect = 0.000e+0
Identity = 303/519 (58.38%), Postives = 388/519 (74.76%), Query Frame = 2

Query:  107 SKPDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNACLRKDNKTRSNKTTNFVSERPYLLKSKKCHCHCRSPLIIDSRDHFNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDAIRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPC-RTKKYQ-----PEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKL---LCCRKSLHHKVTCPTQLDKPLCK 1636
            ++ + RP+ C+PI I MCK IGYNLTY+PN+ +H + EEAGL + QF  LVEI CS++LRLFLCS+YAPICLPNWP  I ACRS+C SAR+GC  VMN YGFKWP+ M+C+KL E+ ACL+KD K         V++ P    SK C C CRSP I D++  FN V+TG ++NC  +C S  F   DKSF TFWLG+WA +C +S++ T+LTF +D+SRF+YPERPI+FLS CY+++S+GY+IRVA+GHE +AC  D +RYG++G   CSIVFL IYFFGMA+S+WWV+LT TWFL+AGLKWGSEAI  Y++I+HF AWF+ G++SI+ LT+ ++DGDPV GICY+GN N  NL  F+I+PL VYLL+G+ FLL+GF+AL+ IRKTI+ KGESKTDKLEKLM+RI IFG++YSVP   V+ C +YE   R+ WE+S  C C R  K Q     PEYSVFMLKYFM LVVG T+GFWIWT KTLDSW   F +L   +C +   H K     + + PLC+
Sbjct:   50 NQENFRPNKCVPIAIPMCKNIGYNLTYMPNEFHHETQEEAGLVVHQFYPLVEIACSDNLRLFLCSLYAPICLPNWPKPIQACRSVCESARDGCAPVMNTYGFKWPKSMDCDKLTENQACLKKDTKN--------VTKPP----SKGCECKCRSPYIYDNKPQFNSVITGGVANCFQSCHSANFVSIDKSFVTFWLGLWAVLCCLSSTATVLTFLLDRSRFKYPERPIVFLSGCYMMVSIGYIIRVAVGHELIACDGDKLRYGTTGPARCSIVFLLIYFFGMAASVWWVILTITWFLSAGLKWGSEAISKYSEIFHFLAWFLSGVKSILALTLVAIDGDPVGGICYIGNTNSLNLKLFLIVPLTVYLLIGSCFLLSGFIALISIRKTIRAKGESKTDKLEKLMMRIGIFGLLYSVPAAVVIGCHLYEVKNREFWEKSNNCYCNRNIKSQENFSKPEYSVFMLKYFMCLVVGITSGFWIWTSKTLDSWHNAFRRLSQSICGQSDKHTKQFPGNEQETPLCQ 556

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BLAST of Frizzled-5 vs. TrEMBL
Match: T1E109 (Fzd-5/8-4 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1)

HSP 1 Score: 618.231 bits (1593), Expect = 0.000e+0
Identity = 301/523 (57.55%), Postives = 386/523 (73.80%), Query Frame = 2

Query:  101 SISKPDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNACLRKDNKTRSNKTTNFVSERPYLLKSKKCHCHCRSPLIIDSRDHFNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDAIRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPC-RTKK-----YQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCK-----LLCCRKSLHHKVTCPTQLDKPLCK 1636
            S +  + RP+ C+PI I MCK IGYNLTY+PN+ +H + EEAGL + QF  LVEI CSE+LRLFLCSMYAPICLPNWP RI ACRS+C SAR+GC  VMN YGFKWP+ M+C+KL ED ACL+KD K  +              KS  C C CR P I+D++  FN V+TG + NC  +C S  F   DKSF TFW+G+WA +C IS++ T+ TF +D+SRF+YPERPI+FLS CY+++S GY+IRVA+GHE +AC+++ +RYG++G   CS+VFL IYFFGMA+S+WWV+LT TWFL+AGLKWGSEAI  Y++I+HF AWF+ G +SI+ LT  ++DGDP++GICY+GN N  +L  F+I PL+VYLL G+ FLL+GF+AL+ IRKTI+ KGE+KTDKLEKLM+RI IFG++YSVP   V+ C IYE   R+LWE+S  C C RT       ++PEYS+FMLKYFM LVVG T+GFWIWT KTLDSW+  F +     L   RK+   K    T+ D PLC+
Sbjct:   54 SSNSENFRPNKCVPIAIPMCKNIGYNLTYMPNEFHHETQEEAGLVVHQFYPLVEIACSENLRLFLCSMYAPICLPNWPKRIRACRSVCESARDGCAPVMNTYGFKWPKSMDCDKLTEDQACLKKDTKNVTKPQ-----------KSNGCDCKCRHPYILDNKPQFNSVITGGVHNCFQSCHSANFVSVDKSFVTFWIGLWAVLCCISSTATVFTFLLDRSRFKYPERPIVFLSGCYMMVSTGYIIRVAMGHELIACENNRLRYGTTGPARCSVVFLLIYFFGMAASVWWVILTVTWFLSAGLKWGSEAIAKYSEIFHFMAWFLSGAKSILALTFVAIDGDPIAGICYIGNTNPLHLKLFLIAPLLVYLLTGSCFLLSGFVALISIRKTIRAKGETKTDKLEKLMMRIGIFGLLYSVPAAVVIGCHIYELKNRELWERSINCLCPRTLTEDVSFFRPEYSIFMLKYFMCLVVGITSGFWIWTTKTLDSWNNAFRQVGRALLGKPRKNNSAKHFLGTEQDTPLCQ 565

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BLAST of Frizzled-5 vs. TrEMBL
Match: A0A2T7PZY2 (Uncharacterized protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_01610 PE=3 SV=1)

HSP 1 Score: 556.214 bits (1432), Expect = 0.000e+0
Identity = 274/524 (52.29%), Postives = 359/524 (68.51%), Query Frame = 2

Query:  122 RPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLP----EDNACLRKDNKTRSNKTTN----FVSERPYLLK----------------------SKKCHCHCRSPLI---IDSRDHFNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDAIRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPCRTKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLCCRKSLHH 1594
            +P  C  I I MCKGIGYN TY+PN  NH + EEAGLE+ QF  LVEI+CS DL+ FLCSMY+PIC+ N+   +PACRS+C  A+ GC  +M QYGF WPE M+CEKLP    +D  C+  +   R     +    + + RP  +                        + C C CR+PL+    DS  ++NK VTG I NC +NC SPYF E +++F+TFW+G+W+ +C ISTS+T+ TF +D  RF+YPERPIIFLS CY ++S+GY+IR+ +GH+ VAC  D +RY ++G   C++VFL IYFFGMASSIWWV+L+ TWFLAAGLKWG EAI  Y+  +H  AW IP ++SI +L MSSVDGDP++GIC+VGN +  NL  FV+ PL +YL++GT FLLAGF++L +IR  IK++G  KTDKLE+LMIRI +F ++Y+VP   V+ C  YE   R+ WE++ TCPC+     P+YSVFMLKYFM LVVG T+GFWIWT KT+DSW K+F   LC   S  H
Sbjct:   66 QPRRCQEITIPMCKGIGYNYTYMPNQFNHETQEEAGLEVHQFWPLVEIHCSPDLKFFLCSMYSPICMSNYRKPLPACRSVCERAKAGCAPLMRQYGFGWPEQMDCEKLPKYGDKDQLCMDANTTDRQTPPPHTKYTYPTARPSGVDFQRPLDHGALPLPPDQAPARSTERDCRCQCRAPLVEVHKDSSSYYNKTVTGGIINCAVNCYSPYFSEDERTFATFWIGLWSILCCISTSMTVSTFFVDMQRFKYPERPIIFLSACYFMVSIGYIIRLIVGHQEVACDGDMVRYETTGPAVCTVVFLLIYFFGMASSIWWVILSFTWFLAAGLKWGQEAIASYSQYFHLVAWLIPSVKSIAVLAMSSVDGDPIAGICFVGNQSLENLRGFVLAPLFIYLIIGTSFLLAGFVSLFRIRSVIKQQGRGKTDKLERLMIRIGVFSVLYTVPATIVIACYFYEQHLRERWERTRTCPCQEGGAAPDYSVFMLKYFMCLVVGITSGFWIWTGKTVDSWRKLFYGKLCHTHSYSH 589

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BLAST of Frizzled-5 vs. Ensembl Cavefish
Match: ENSAMXT00000026985.2 (pep primary_assembly:Astyanax_mexicanus-2.0:19:27065879:27070162:-1 gene:ENSAMXG00000026259.2 transcript:ENSAMXT00000026985.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 514.612 bits (1324), Expect = 1.139e-176
Identity = 260/509 (51.08%), Postives = 348/509 (68.37%), Query Frame = 2

Query:  134 CIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLP----EDNACLRKDNKTRSNKTTNFVSERP-----YLLKSK-----KC--HCHCRSPLI-IDSRDH--FNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDA----IRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPCRTKKYQ----PEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLCCR 1579
            C PI + MCKGIGYNLTY+PN  NH + EE GLE+ QF  LV I CS DL  FLCSMY PICLP++   +P CRS+C  A+ GC+ +M QYGF+WPE M+CE+LP     D  C+ +++   +  + +F    P     +   SK     KC   C CR PL+ I    H  +N+V TG++ NC + C  PYF + +++F+TFW+G+W+ +C +ST  T+ TF ID  RF+YPERPIIFL+ CYL +S+GY++R+  GHE VAC        I Y ++G   C++VFL IYFFGMASSIWWVVL+ TWFLAAG+KWG+EAI  Y+  +H  AW +P ++SI +L +SSVDGDPV+GICYVGN +  +L  FV+ PL+VYL  G+ FLLAGF++L +IR  IK+ G +KTDKLEKLMIRI +F ++Y+VP   VV C +YE  +R  WEQ+  C C +++ Q    P+Y+VFMLKYFM LVVG T+G WIW+ KTL+SW +   +   CR
Sbjct:   37 CEPITVPMCKGIGYNLTYMPNQFNHDTQEEVGLEVHQFWPLVRIRCSPDLLFFLCSMYTPICLPDYKKPLPPCRSVCERAKRGCSPLMIQYGFEWPERMSCEQLPMLGDPDRLCMDQNSSETTTLSPSFPKPTPRGSSRHRATSKSAVPQKCDRECRCREPLVPIKKESHPLYNRVQTGSLPNCALPCHQPYFSQDERAFTTFWIGLWSVLCFVSTLTTVATFLIDMERFKYPERPIIFLAACYLFVSLGYIVRLLAGHEKVACGGSGDQRHILYDTTGPALCTLVFLLIYFFGMASSIWWVVLSFTWFLAAGMKWGNEAIAGYSQYFHLAAWLVPSVKSIAVLALSSVDGDPVAGICYVGNQSLESLRGFVLAPLVVYLFSGSLFLLAGFVSLFRIRSVIKQGG-TKTDKLEKLMIRIGLFTVLYTVPATIVVACLVYEQHYRPEWEQALGCSCASERQQQGLGPDYAVFMLKYFMCLVVGITSGVWIWSGKTLESWRRFVARCFPCR 544

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BLAST of Frizzled-5 vs. Ensembl Cavefish
Match: fzd8a (frizzled class receptor 8a [Source:ZFIN;Acc:ZDB-GENE-000328-3])

HSP 1 Score: 444.506 bits (1142), Expect = 1.055e-149
Identity = 241/516 (46.71%), Postives = 327/516 (63.37%), Query Frame = 2

Query:   74 LFRICGQSFSISKPDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPAC---RSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNACLRKDNKTRSNKTTNFVSERPYLLKSKKCH--CHCRSPLI-IDSRDH--FNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSD----AIRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPCRTKK--YQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLCCR 1579
            LF   G     S    +  TC  I + +CKG+GYN TY+PN  NH + +EAGLE+ QF  LVEI CS DLR FLCSMY PICL ++   +P      +LC+      +   +    K         +P         ++T+  +      + P       C   C CR+P++ ++S  H  +N+V TG + NC M C +PYF + +++F+ FW+G+W+ +C +ST  T+ TF ID  RF+YPERPIIFLS CY+ +S+GY++R+  GHE VAC  +     + Y ++G   C++VFL IYFFGMASSIWWV+L+ TWFLAAG+KWG+EAI  Y+  +H  AW IP ++SI +L +SSVDGDPV+GICYVGN N  NL  FV+ PL++YL +GT FLLAGF++L +IR  IK+ G +KTDKLEKLMIRI IF ++Y+VP   +V C  YE   R  WE S+ C C  +    +P+Y+VFMLKYFM L VG T+G WIW+ KTLDSW     + LC R
Sbjct:   12 LFLALGTLQRSSGTTAKELTCQEIAVPLCKGVGYNHTYMPNQFNHDTQDEAGLEVHQFWPLVEIQCSPDLRFFLCSMYTPICLEDYKKPLPVQGDPDTLCMDYNRTDSTTASPVLSKPTGRPGKPHVPP--------HRTKHGRPG---VQPPKRKPGSPCDPGCQCRAPMVRVNSERHPLYNRVKTGQMPNCAMPCHNPYFTQDERTFTAFWIGLWSVLCFVSTFATVATFLIDMERFKYPERPIIFLSACYMFVSIGYIVRLIAGHEKVACSREYDVEHVHYETTGPALCTVVFLLIYFFGMASSIWWVILSLTWFLAAGMKWGNEAIASYSQYFHLAAWLIPSMKSIAVLALSSVDGDPVAGICYVGNQNLDNLRGFVLAPLVIYLFIGTMFLLAGFVSLFRIRSVIKQGG-TKTDKLEKLMIRIGIFTVLYTVPATIIVACYFYEQHNRQSWETSHNCSCLMEHELRRPDYAVFMLKYFMCLSVGITSGVWIWSGKTLDSW-----RALCTR 510

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BLAST of Frizzled-5 vs. Ensembl Cavefish
Match: fzd7b (frizzled class receptor 7b [Source:ZFIN;Acc:ZDB-GENE-990415-229])

HSP 1 Score: 389.808 bits (1000), Expect = 2.787e-128
Identity = 218/507 (43.00%), Postives = 306/507 (60.36%), Query Frame = 2

Query:  134 CIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNA---CLRKDNKTRSNKTTNFVSERPYLL---KSKKCHCHCRSPLIIDSRDHFNKVVTGNISNCLMNCRSP------YFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVAC----KSDAIRYGSSGAVP--CSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSY---TC-----PCRTKKY---QPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKL 1567
            C PI I +C  I YN T +PN L H + E+AGLE+ QF  LV++ CS DL+ FLCSMYAP+C       IP CRSLC  AR GC  +MN++GF+WPE + CE  P   A   C+ ++     + T+      P L      ++       PL +    + N    G   +C   C         YF E +  F   W+GIWA +C +ST  T+LT+ +D  RF+YPERPIIFLS CY +++V Y+    L  + V C    + DA R  + G     C+I+F+ +YFFGMASSIWWV+L+ TWFL+AG+KWG EAI   +  +H  AW +P +++I IL +  VDGD ++G+C+VG  N   L  FV+ PL VYL +GT FLLAGF++L +IR  +K  G +KT+KLEKLM+RI +F ++Y+VP   V+ C  YE  FR+ WE+++   TC     PC +  +    P+++VFM+KY M ++VG T+GFWIW+ KTL SW   + +L
Sbjct:   50 CQPISIPLCTDIQYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSADLKFFLCSMYAPVCT-VLEQAIPPCRSLCERARHGCEALMNKFGFQWPERLRCEAFPVHGAGEICVGQNTSDPGSPTSEPTLYAPGLTPPPGPERSGQPFTCPLQLAVPSYLNYKFLGA-KDCGAPCEHSQPHGLMYFREEEMKFGRLWVGIWAILCCVSTLFTVLTYLVDMRRFRYPERPIIFLSGCYFMVAVAYVTGFLL-EDKVVCIDKFREDAYRTVAQGTKKEGCTILFMILYFFGMASSIWWVILSLTWFLSAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILALGQVDGDLLTGVCFVGIYNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDG-TKTEKLEKLMVRIGVFSVLYTVPATIVIACYFYEQAFREQWEKTWHMQTCKRFAVPCPSSNFAPMSPDFTVFMIKYLMTMIVGITSGFWIWSGKTLQSWRSFYKRL 552

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BLAST of Frizzled-5 vs. Ensembl Cavefish
Match: fzd9b (frizzled-9 [Source:NCBI gene;Acc:103027133])

HSP 1 Score: 390.193 bits (1001), Expect = 4.014e-128
Identity = 230/548 (41.97%), Postives = 317/548 (57.85%), Query Frame = 2

Query:   68 WVLFRICGQSFSISKPDL---RPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNA----CLR---KDNKTRSNKTTNF--VSERP-----YLLKSKKCHCHCRSPLIIDSRDHFNKVVTGNISNCLMNCRSP---YFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDA-----IRYG--SSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFI------FRDLWEQSYTCP------CRTKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLCCRKSLHH 1594
            W    I   S  I   D    RP+ C PI I MC+GIGYNLT +PN ++H S +EA +++ +F  LVE  C   LR FLCS+YAP+C       IPACR +C  AR+ C+ +M ++ + WPE ++C KLP  N     C+     D K    K      V  RP        +       C +P      + F  V      +C   C S    ++   DK F+  W+ +W+ +C +ST+ T+LTF +D  RFQYPERPIIFLS+CY + SV ++IR   G E +AC  +      I+ G  S+G   C+IVFL +Y+FGMASSIWWV+LT TWFLAAG KWG EAI  ++  +H  AW IP +++I+ILTM  V GD ++G+CYVG+++   L  FV++PL  YL+VGT F+L GF+AL  IRK +K +G + T+KLEKLM++I I+ I+Y+VP   V+ C  YE +      FR L  +  T P      C      P  +VFMLK FM+LVVG T+G W+W+ KTL +W  +  + L  R S  H
Sbjct:   17 WCQLVIAVSSLEIGSYDFERGRPAKCEPIVIPMCQGIGYNLTRMPNFMDHDSQKEAAIKLNEFAPLVEYGCDVHLRFFLCSLYAPMCTDQVSTSIPACRPMCEQARQRCSPIMEKFNYAWPESLDCSKLPTRNDPNALCMEAPENDTKPEPKKGEGMLPVPPRPRQPGSGGGRPGGSVGACENP------EKFQYVEKSE--SCAPRCSSAVDVFWSRQDKDFAFIWMAVWSTLCFVSTAFTVLTFLLDPHRFQYPERPIIFLSMCYNVYSVAFIIRSVAGAENIACDRENGELYIIQEGLESTG---CTIVFLILYYFGMASSIWWVILTLTWFLAAGKKWGHEAIESHSSYFHMAAWGIPALKTIVILTMRKVAGDELTGLCYVGSMDVGALTGFVLVPLSFYLVVGTSFVLTGFVALFHIRKVMKTEG-TNTEKLEKLMVKIGIYSILYTVPATCVIVCYFYERLNMDYWKFRGLESKCVTFPGRRNEDCSLDASMPAVAVFMLKIFMSLVVGITSGVWVWSSKTLQTWQGLCSRKLADRTSRKH 552

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BLAST of Frizzled-5 vs. Ensembl Cavefish
Match: fzd9a (frizzled class receptor 9a [Source:ZFIN;Acc:ZDB-GENE-060531-77])

HSP 1 Score: 387.497 bits (994), Expect = 5.586e-127
Identity = 222/548 (40.51%), Postives = 312/548 (56.93%), Query Frame = 2

Query:   59 LFSWVLFRICGQSFSISKPDL---RPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNA----CLRKDNKTRSNKTTNFVSERPYLLKSKKCHCHCRSPLIIDS--RDHFNKVVTGNISNCLMNCRSPYFGEF----DKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSD-----AIRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWE------------QSYTCPCRTKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLCCRKSLHHKVTCPT 1612
            +F W      G S  I   D    RP+ C PI I MC+GIGYN+T +PN + + S EEA +++ +F  LVE  C   LR FLCS+Y P+C       IPACR++C+ AR+ C+ +M Q+ F WP+ ++C KLP +N     C+          T       P   + +        P        +H          +C   C SP    F    DK F+  W+ +W+ +C +ST+ T+LTF +D  RFQYPERPIIFLS+CY + SV ++IR   G E +AC  +      I+ G   +  C+IVFL +Y+FGMASSIWWV+LT TWFLAAG KWG EAI  ++  +H  AW IP +++I+ILTM  V GD ++G+CYVG+++   L  F+IIPL  YL++GT F+L GF+AL  IRK +K  G + T+KLEKLM++I +F I+Y+VP   V+ C  YE +  D W+               T  C      P  +VFMLK FM+LVVG T+G W+W+ KTL +W  +  + L  R +   +  CP+
Sbjct:   23 IFLWCQLVSDGSSLDIGAYDGERGRPAKCEPITIPMCQGIGYNMTRMPNFMKYESQEEASIKLNEFAPLVEYGCDVHLRFFLCSLYVPMCTDQVSTTIPACRAMCVQARQKCSPIMEQFSFGWPDSLDCSKLPTNNDPNALCIEAPENDTVPPTKKGEGMLPVPARPRPPGTGAGRPSGGSGSCENHEKFQYVEKSESCAPRC-SPTVDVFWSRQDKDFAFIWMVVWSTLCFVSTAFTVLTFLLDPQRFQYPERPIIFLSMCYNVYSVAFIIRSVAGAENIACDRENGQLYIIQEGLE-STGCTIVFLILYYFGMASSIWWVILTLTWFLAAGRKWGHEAIEAHSSYFHMVAWGIPAMKTIVILTMRKVAGDELTGLCYVGSMDTNALTGFIIIPLSCYLIIGTSFILTGFVALFHIRKIMKTGG-TNTEKLEKLMVKIGVFSILYTVPATCVIICYFYERLNMDYWKFRASESKCVSFPGRRTEDCTLDSSVPTVAVFMLKIFMSLVVGITSGVWVWSSKTLQTWQGLCARKLAMRTT---RKPCPS 564

[Close]

BLAST of Frizzled-5 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000011009.1 (pep scaffold:Pmarinus_7.0:GL485859:2701:4509:1 gene:ENSPMAG00000009982.1 transcript:ENSPMAT00000011009.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 486.108 bits (1250), Expect = 5.044e-166
Identity = 248/527 (47.06%), Postives = 342/527 (64.90%), Query Frame = 2

Query:  122 RPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLP------------------------EDNACLRKDNKTRSNKTTNFVSERPYLL---KSKKCHCHCRSPLI-IDSRDH--FNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDA--IRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCP-CRTKK---------YQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLCC 1576
            R   C  I + MC+GIGYN TY+PND NH S +EAGLE+ QF  LVEI CS DLR FLCSMY PICL ++   +P CRS+C  AR GC  +M QYGF WP+ M C++LP                        +  A +R  N +++  TT             ++ +  C CR+P++ I S  H  +N+V TG++ NC M C  PYF + +++F++FW+G+W+ +C +ST  T++TF ID  RF+YPERPIIFLS CY  +S+GY++R+ +GH+ V C  +   + Y ++G   C++VFL  YFFGMASSIWWV+L+ TWF+AAG+KW SEAI  Y+  YH  AW +P +QS+ +L  SSVD DP++GIC VG  +  NL  FV++PL VYL VG  FLLAGF +L++IR  IK++G +KTDKLEKLM+RI IF ++Y+VP + VV C  YE   RD W ++  CP C+  +          +P+Y +FMLKYFM LVVG T+G WIW+ KT+D+W ++ C+  CC
Sbjct:    5 REMLCQNITVPMCRGIGYNHTYMPNDFNHDSQDEAGLEVHQFWPLVEIKCSPDLRFFLCSMYTPICLEDYKQPLPPCRSVCERARAGCAPLMRQYGFAWPDRMRCDRLPVLGDQNRLCMDYNKSDTTPQPPEVKPTAPVRSFNPSKNRATTRVGGGGGGGGGSGEACESGCACRAPMVAIGSDRHPLYNRVRTGSVLNCAMPCHDPYFTQDERTFASFWIGLWSILCFVSTFTTVVTFLIDMERFKYPERPIIFLSACYAFVSMGYIVRLVVGHDGVICNQEHRHVHYETTGPALCTVVFLLTYFFGMASSIWWVILSLTWFMAAGMKWSSEAIAGYSQYYHLAAWLLPSVQSVAVLATSSVDADPLAGICSVGAQSLENLRGFVLVPLTVYLCVGAVFLLAGFTSLVRIRNAIKQQGGTKTDKLEKLMVRIGIFSMLYTVPAIAVVACYFYEERSRDGWARALICPSCQGDEEPGSQQQQQQRPDYGIFMLKYFMCLVVGITSGVWIWSGKTVDTWKRLCCR--CC 529

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BLAST of Frizzled-5 vs. Ensembl Sea Lamprey
Match: fzd2 (frizzled class receptor 2 [Source:ZFIN;Acc:ZDB-GENE-990415-224])

HSP 1 Score: 385.571 bits (989), Expect = 1.313e-127
Identity = 223/524 (42.56%), Postives = 306/524 (58.40%), Query Frame = 2

Query:  134 CIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLP---EDNACLRKDNKTRSNKTT---------------------NFVSERPYLLKSKKCHCHCRSPLIIDSRDHFNKVVTGNISNCLMNC--RSP----YFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKS---DAIRYGSSGAVP--CSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQS--------YTCPCRTKKY---QPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKL 1567
            C PI I +C  I YN T +PN L H + E+AGLE+ QF  LV++ CS DL+ FLCSMYAP+C       IP CRSLC  AR+GC  +MN++GF+WPE + CE  P    D  C+ +++  ++  T                      +FV+        +     C  P ++    + N  +     NC   C  + P    YF E +  FS  W+GIW+ +C  ST  T+ T+ +D  RF+YPERPIIFLS CY +++V Y+    L  + V  +    D  R  + G     C+I+F+ IYFF MASSIWWVVL  TWFLAAG+KWG EAI   +  +H  AW IP +++I IL M  VDGD +SG+C+VG  +   L  FV+ PL VYL +GT FLLAGF++L +IR  +K  G +KT+KLEKLM+RI IF ++Y+VP   V+ C  YE  FR+ WE++        +  PC    Y   +P+++VFM+KY M L+VG T+GFWIW+ KTL SW K + KL
Sbjct:   13 CQPISIPLCTDIPYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSPDLKFFLCSMYAPVCT-VLEKAIPPCRSLCDRARQGCEALMNKFGFQWPERLRCENFPVQGSDEICVGQNHTDKAGPTALPPTPPGGGGGVIGGIGGGAGDFVTIHTRRPPGRTHPFMC--PRVLKVPPYLNAQLFRE-RNCAAPCEPKKPNGLMYFSEEELRFSRLWVGIWSVLCCASTLFTVTTYLVDMQRFRYPERPIIFLSGCYFMVAVAYVAGFLLDDKVVCNEQFSEDIYRTVTQGTKKEGCTILFMLIYFFSMASSIWWVVLALTWFLAAGMKWGHEAIEANSQYFHLAAWAIPAVKTITILAMGLVDGDMLSGVCFVGISSVAALRGFVLAPLFVYLFLGTSFLLAGFVSLFRIRTIMKHDG-TKTEKLEKLMVRIGIFSVLYTVPATIVIACYFYEQAFREQWEKTWVSQSCKGFAIPCPLNHYPNMKPDFTVFMIKYLMTLIVGITSGFWIWSGKTLHSWRKFYTKL 531

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BLAST of Frizzled-5 vs. Ensembl Sea Lamprey
Match: fzd8a (frizzled class receptor 8a [Source:ZFIN;Acc:ZDB-GENE-000328-3])

HSP 1 Score: 340.117 bits (871), Expect = 4.698e-112
Identity = 175/363 (48.21%), Postives = 241/363 (66.39%), Query Frame = 2

Query:  551 CHCRSPLI-IDSRDH--FNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSD--AIRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEK-GESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPC--------RTKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLCCRKSLHHK 1597
            C CR+PL+ I +  H  +++V TG + NC   C SP+ G   ++F++FW+G+W+ +C  +T  T+ TF ID  RF+YPERPIIFLS+C +L S+GY++R+  GHEAVAC +D   + Y SSG   C+ VFL  YFFGMA  +WWV+L+ TWF+AAGLKWGSEAI  Y+  YH  AW +P I++I  L M++VDGDPV+GIC VGN +  NL  FV+ PL+ YLLVGT FLLAG +AL +IR  I    G +KT+KLE+LM+RI +F ++Y+VP    V C +YE   RD WE++  C               +P+++VFMLKYF+ LV G T+G WIW+ KT  SW + + +    R    H+
Sbjct:    5 CGCRAPLVRISNPRHVLYDRVRTGQVRNCATPCHSPFLGREQRTFASFWIGLWSSLCFAATFATVSTFLIDMERFKYPERPIIFLSLCCMLASLGYIVRMVAGHEAVACSADWHHVLYASSGPALCTAVFLLTYFFGMAGCVWWVILSLTWFMAAGLKWGSEAIAGYSQYYHLAAWLLPSIKAIAALAMNAVDGDPVAGICSVGNQSLDNLRGFVLAPLVAYLLVGTAFLLAGLVALFRIRNAISANPGGAKTEKLERLMVRIGVFAVLYTVPAAVAVVCHLYEQQHRDSWERTLVCGACGPGPGHLPEPGARPDFAVFMLKYFVCLVGGITSGAWIWSGKTAGSWKRFYKRCRAWRAGKRHR 367

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BLAST of Frizzled-5 vs. Ensembl Sea Lamprey
Match: fzd7a (frizzled class receptor 7a [Source:ZFIN;Acc:ZDB-GENE-990415-223])

HSP 1 Score: 266.159 bits (679), Expect = 3.411e-81
Identity = 151/331 (45.62%), Postives = 212/331 (64.05%), Query Frame = 2

Query:  620 SNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDAIRYGS----SGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQS---YTC-----PCRTKKY---QPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKL 1567
            SN LM     YF   +  F+  W+G+W+ +C  ST  T+LT+ +D  RF+YPERPIIFLS CY ++S+ Y++      + V  K     Y +    +    C+I+F+ +YFF MASSIWWV+L+ TWFL+AG+KWG EAI   +  +H  AW +P I++I IL M  VDGD ++G+C+VG  +   L  FV+ PL VYL +GT FLLAGF++L +IR  +K  G +KT+KLEKLM+RI IF ++Y+VP   V+ C  YE  FR  WE+S   +TC      C    Y   +P+++VFM+KY M L+VG T+GFWIW+ KTL SW   + +L
Sbjct:  261 SNGLM-----YFDADELWFARMWVGVWSILCCASTLFTVLTYLVDMERFRYPERPIIFLSGCYAVVSIAYIVGFFFEEKIVCNKFFEDSYSTVVQGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLSAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILAMGQVDGDVLTGVCFVGLNSIDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDG-TKTEKLEKLMVRIGIFSVLYTVPATIVIACYFYEQAFRAQWEKSWVAHTCKSFAVQCPQGHYPNMKPDFTVFMIKYLMTLIVGITSGFWIWSGKTLQSWRNFYSRL 585

HSP 2 Score: 127.872 bits (320), Expect = 2.116e-31
Identity = 58/118 (49.15%), Postives = 78/118 (66.10%), Query Frame = 2

Query:  134 CIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLP---EDNACLRKDN 478
            C PI I +C  I YN T +PN L H + E+AGLE+ QF  LV++ CS DL+ FLCSMYAP+C       IP CRSLC  AR+GC  +MN++GF+WPE + CE  P    +N C+ +++
Sbjct:   57 CQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSPDLKFFLCSMYAPVCT-VLEEAIPPCRSLCERARQGCETLMNKFGFQWPERLRCENFPVQGSENICVGQNH 173

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BLAST of Frizzled-5 vs. Ensembl Sea Lamprey
Match: fzd3b (frizzled class receptor 3b [Source:ZFIN;Acc:ZDB-GENE-070122-1])

HSP 1 Score: 214.927 bits (546), Expect = 3.479e-63
Identity = 124/332 (37.35%), Postives = 191/332 (57.53%), Query Frame = 2

Query:  614 NISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDAIRYGSSGAV--------PCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQS--------YTCPCRTKKYQPEYS----VFMLKYFMNLVVGTTAGFWIWTPKTLDSWS 1549
             + +C   C + YF   +   + + +G+ + VC+++T+ T LTF +D+ RF+YPERPIIF + CY+ +S+ +L+   L   A AC +  +  G++G V         C+ VF+ +YF  MA ++WWVVLT TWFLAAGLKWG EAI   A  +H  AW  P   ++ +L ++ V+GD +SG+CY G  +   L +FV+ PL      G   LLAG ++L ++R  ++  G ++T KL K M+RI +F ++Y VP + +V C +YE   R  WE +        Y  PC  +  QP+      +F++KYF  LVVG    FW+ + KT   W+
Sbjct:   26 GVPDCSPPCPNMYFSSGELELTRYLVGVMSVVCLVATTFTFLTFLLDRKRFRYPERPIIFYATCYVAVSLSFLVGFLLDDSAAACNAPGLAPGAAGTVTQGSRNNKACTAVFMLLYFSAMAGALWWVVLTITWFLAAGLKWGREAIEKRAAAFHALAWGPPAALTVALLALNKVEGDNLSGVCYAGLYDVTTLRYFVLAPLGACAAAGLSLLLAGIVSLNRVRLEMRHDGRNQT-KLVKFMVRIGVFSVLYLVPQLALVACLVYEQASRAAWEATWLRDRCTEYRIPCPYQANQPKQRPALVLFLVKYFTTLVVGIPPAFWVGSRKTCLGWA 356

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BLAST of Frizzled-5 vs. Ensembl Nematostella
Match: EDO42932 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S003])

HSP 1 Score: 482.256 bits (1240), Expect = 3.915e-165
Identity = 251/494 (50.81%), Postives = 336/494 (68.02%), Query Frame = 2

Query:  134 CIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPE----DNACLRKDNKTRSNKTTNFVSERPYLLKSKKCH------CHCRSPLIIDSRDHFN---KVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDAI-RYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCP-CRTKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLL 1570
            C  I I MC+GIGYNLTY+PN  NH +  EA LE+ QF  LVEI CS DLR FLCSMYAP+C  ++   +P CRS+C  AR GC  +M +YGF WPE M CE  PE    +  C+ +++   S ++T   S+ P    S          C CR P +  +  +      +  G +  C M C   YF     SF++FW+G+WA +C IST VT LTF +D  RF+YPERPIIFLS CYL++SVGY+IR+  GH+ +AC S+ + RY +SG   C+IVFL +YFFGMASS+WWV+L  TWFL+AG+KW SEAI  Y+  +H  AW +P IQ+I +L MS++DGDPVSGICYVGN N  +L+ FVI+PL+VYL+ GT FL+AGF +L++IRK +++ G +KTDKLEKLMIRI +F ++Y+VP   VV C  YE + R+ WE++  C  C   + +P++SVF++KYFM LVVG T+GFWIW+ KT++SW + FC  L
Sbjct:   29 CEEITIPMCRGIGYNLTYMPNMFNHDTQAEAALEVHQFWPLVEIQCSPDLRFFLCSMYAPLCEKHYDKDLPPCRSVCERARTGCAPLMRKYGFSWPERMKCENFPELGDENTLCMGRNS---SGESTPKPSQSPQPAPSPDTAAISANCCSCRPPFVSIAGKNIKPTRAISVGGVPQCAMACNRTYFTHDQDSFASFWIGLWAILCFISTLVTTLTFLVDMHRFKYPERPIIFLSGCYLMVSVGYIIRLIAGHKQIACDSNGLMRYDTSGPASCTIVFLLVYFFGMASSVWWVILAFTWFLSAGMKWSSEAITNYSQYFHAVAWLVPAIQAIAVLAMSTIDGDPVSGICYVGNHNLQSLVVFVIVPLVVYLVFGTSFLMAGFYSLVRIRKLLRQHGSTKTDKLEKLMIRIGVFSVLYTVPATIVVACYYYELVNRETWERTINCSGCGVTRVKPDHSVFIIKYFMALVVGITSGFWIWSGKTIESW-RNFCARL 518

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BLAST of Frizzled-5 vs. Ensembl Nematostella
Match: EDO38567 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCF4])

HSP 1 Score: 393.275 bits (1009), Expect = 1.489e-129
Identity = 228/535 (42.62%), Postives = 317/535 (59.25%), Query Frame = 2

Query:   50 ISLLFSWVLFRICGQSFSISKPDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNACLRKDNKTR----------------SNKTTNFVSERPYLLKSKKCHCHCRSPLIIDSRDHFNKVVTGNISNCLMNCRSP-YFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVAC---KSDAIRYGSSGA--VPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWE-----QSYTCPCRT---KKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCK 1564
            I LLF  V   + GQ     + ++  S C PI I +C GIGYN T  PN L   S EEA   I +F  L+ +NC+  LR FLCS++ P+C       I ACRS+C SAR+GC+ +M ++GF WP+ ++C++LP+      K + T+                S+  +NF S  P   K      +   PL       +          C+  C+S   F   +K F+  W+ +W+ +C IST+VT+LTF ID SRF+YPERPIIFLS+CY L S+GY++RV  G   V C   +S  IR G + A    CS+VFL +Y+FGMAS++WWVVLT  WFLAAG KWG EAI   A  +H  AW +P IQ+I+ L M  VD D ++G+CYVGN++  NL  +V+ PL +YLLVGT FLLAGF++L +IR  +K K E+ TDKLEKL++RI +F ++Y++P   V+ CS YE+   D+W+      +Y C       + Y P   VF++KYFM L++G T+  WIW+ KT  SW K + K
Sbjct:    9 ILLLFITVSAMVYGQ-----RSEVPNSKCTPITIPLCMGIGYNATRFPNFLAQESQEEAAKRIHEFKPLIAVNCAPLLRFFLCSVFVPMCTKEVNVPIYACRSMCESARDGCSPMMQRFGFNWPDTLDCDRLPKKGDPQAKSDPTKLCMAAPNIKQTAPLNESDIWSNFESLGPEFKK-----INNTGPL------RYKYTYVEKYDQCVPQCKSDLMFSSNNKRFANVWISVWSVLCFISTAVTVLTFVIDTSRFKYPERPIIFLSLCYNLYSLGYIVRVTAGRNEVICDETESFVIRAGMNIADHACCSVVFLLLYYFGMASAVWWVVLTFAWFLAAGRKWGQEAIERKATYFHAVAWTVPAIQTIMALIMRKVDADELTGLCYVGNMDYENLANYVLTPLCLYLLVGTFFLLAGFVSLFRIRTVLKNK-ETNTDKLEKLIVRIGVFSVLYTIPVSAVIACSFYEYNNMDVWKVRAPFNTYICRGDQACLENYGPSIEVFIVKYFMLLIIGITSNMWIWSTKTFKSWRKFYSK 526

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BLAST of Frizzled-5 vs. Ensembl Nematostella
Match: EDO35751 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKM6])

HSP 1 Score: 382.104 bits (980), Expect = 5.649e-126
Identity = 211/526 (40.11%), Postives = 315/526 (59.89%), Query Frame = 2

Query:  110 KPDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPE--DNACLRKDNKTRSNKTTNFVSERPYL---LKSKKCHCHCRSPLIIDSRDHFNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDAIRYG-------SSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSY---------------------TCPCRTKKYQ-PEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLCCRKS 1585
            +P L    C P+ I +C G+ YN+T  PN L H + EEA LE+ QF  LV+++CS+DL  FLCS+YAP+C       +P CRSLC++ R GC  +M ++GF WP+ ++CE+ P+  D  C+ ++  T ++     ++   Y    + + +  C   S  I + +  F+         C   CR+ +F + ++  +  W GIWA +C +ST  TILTF ID  RF+YPERPIIFLS CY ++S+ ++     G + +AC ++ I+ G        +    C+++F+ +YFF MASSIWWV+LT TWFLAAGLKWG EAI   +  +H  AW IP +++I IL M+ VDGD +SG+CYVG  +   L  +V+ PL VY ++G  FLLAGF++L ++R  +K+   SK +K+EKLMIRI +F I+Y+VP + V+ C  YE   R+LW+ S+                     +CP      Q P++ VFM+KY M L+VG T+GFWIW+ KTL+SW + + + +   K 
Sbjct:   21 RPCLPLKRCEPVTIPLCTGLQYNMTIFPNTLKHRTQEEAALEVHQFFPLVKVDCSKDLAFFLCSVYAPVCT-VLETPLPPCRSLCLTVRSGCEGLMKRFGFTWPDSLSCERFPKLGDEICVGENTTTPTSDQDGGINNNTYPDVDMSTMRYRCP-ESQKIPNDQYTFH-----GEKRCAATCRNVFFTKREREIARMWTGIWAILCAVSTLFTILTFLIDMRRFRYPERPIIFLSGCYFMVSIAFITGYVAG-DKIAC-NEPIKKGFPKTLVQGTKHEGCTVIFMMLYFFSMASSIWWVILTVTWFLAAGLKWGQEAIEANSQFFHLAAWAIPAVKTIAILLMTKVDGDELSGVCYVGLSDVSALRGYVLAPLFVYFIIGATFLLAGFISLFRVRSVLKDD-YSKREKIEKLMIRIGVFSILYTVPALVVIGCLYYEQSNRELWDNSWIEGWKRQKKCTEVETKLKGEVSCPPYPVPLQKPDFMVFMVKYLMFLIVGITSGFWIWSSKTLNSWRRFYRRFILREKG 536

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BLAST of Frizzled-5 vs. Ensembl Nematostella
Match: EDO30865 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SZJ6])

HSP 1 Score: 327.02 bits (837), Expect = 4.373e-105
Identity = 193/497 (38.83%), Postives = 289/497 (58.15%), Query Frame = 2

Query:  134 CIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCS-EDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKL----PEDNACLRKDNKTRSN-------KTTNFVSERPYLLKSKKCHCHCRSPLIIDSRDHFNKVVTGNISNCLMNC-RSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDAIRY------GSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPCRTKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKL 1567
            C  I I +C+ +GYN+T +PN + H + +EA  +++QF  L++  C+ E L  FLCS YAP+C       I +CR LC   R+ C  V+ ++G  WP  +NC +      E N C+   N T S        K  N  +E+P    S++C          +S+++F      +  +C + C     F   DK     W+ IW+  C IST++T+ TF I+  RF+YPER II+L++CY   S+ Y+IR+  G +A++C +D   +             C+IVFL  YFF MA++IWWVVL  TWFLAAG+KWG EAI  YA ++H  AW +P I++I IL    VDGD ++G+C+VGN +   L  FV+ P   YL++GT FL+AGF+AL +IR T++  G++KTDKLE+L++RI IF ++ +VP   V+ C  YE+  ++ W   Y         +P +S+FMLK FM+L  G   G WIW+ KT+++W   + K+
Sbjct:    4 CEKISIDLCRSVGYNVTRMPNLIGHETQKEAESQLKQFLPLIQYGCAREQLVFFLCSAYAPMCTDKVDVVITSCRPLCEYVRKSCLPVLTEFGIPWPNPLNCTRFLVRNNERNMCMPGPNFTESPEKPRPDFKPINDTTEKPPSTGSEQCR------RFKNSKNYF---YVQSTESCAVRCNEDGIFKTSDKETMDIWITIWSIFCFISTTITLTTFLIETGRFKYPERSIIWLALCYNFYSLSYIIRLGAGRQAISCDTDPTTHVKFHIQDGLRNTGCAIVFLIQYFFCMAATIWWVVLALTWFLAAGMKWGCEAIGSYAKLFHIIAWILPCIKTIFILITRKVDGDELTGLCFVGNQDLIALAAFVLGPQFTYLIIGTLFLIAGFVALFRIRTTVQRGGQAKTDKLERLIVRIGIFSVLSTVPATAVIACYFYEYANKEYW---YYGQRDGAVAEPNFSIFMLKVFMSLFTGVITGMWIWSHKTMNTWRAFYYKV 488

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BLAST of Frizzled-5 vs. Ensembl Nematostella
Match: EDO40119 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S829])

HSP 1 Score: 142.124 bits (357), Expect = 3.379e-36
Identity = 137/547 (25.05%), Postives = 238/547 (43.51%), Query Frame = 2

Query:   71 VLFRICGQSFSISKPDLRPS-TCIPIEISMCKGIGYNLTYIPNDL--NHASLEEAGLEIQQFNALVEI-NCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNACLRKDNKTRSNKTTNFVSERPYLLKSKKCHCHCRSPLIIDSRDHFNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCID-KSRFQYPERPIIFLSICYLLMSVGYLIRVAL-GHEAVACK-SDAIRYGS---SGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLA-AGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTD-KLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSY-----------------TCPCRTKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLCCRKSLHHKVTCPTQLDK 1624
            VL   CG   S S    + S  C P++   C G   +  Y   +L  + +S ++    ++++  L  +  C E L+ FLC +Y P C  N    +P CR  C + R+ C+ V+  Y  +WPE + C+KLPE N C     K   N++                   C++PL+      +       I  C + C +P F E + +    ++  +  +  + T  T++TF +  KS+ +YP   + F++ C+ + SVG+LI+ +      V C+  D +R G    S +  C + F+ +Y+F +A   W+V+L  +W +    L    +        +H  +W +P + +  +L +  VD + +SGIC+VG  N      F++ PL + L++G  FL  G   L K+RK+      ++   K+++ ++R+  F  V          C +YE+  ++ WE+SY                 TC  + +       + +   F     G     W WT  T  +W           K L H+VT    L K
Sbjct:    4 VLITFCGIITSYSSAYSQGSYKCEPLKEQTCLGEKLDYHYTTTELVTDSSSQDQVKKNLEKWEGLKFLPKCWEVLQPFLCQIYKPKC-KNGSVELP-CREQCFATRKPCS-VVESYR-RWPEFLRCDKLPEGN-CNGTLKKLHLNESA------------------CKAPLV---ETAYKPSWYEGIEGCGIQCMNPIFSEEEHTRIHRFVAAFGTLTTVCTLFTVVTFLVGWKSQNRYPSVILFFMNACFCVASVGFLIQFSSDARRKVVCRRDDTMRLGEPTESDSFLCVLTFVLVYYFSLAGMTWFVMLAYSWCICFKTLGSTRDNFAGKTGYFHIISWSLPAVLTGCVLLVKQVDANSISGICFVGYKNPSMRAGFLLAPLGLDLVIGGMFLAKGLFTLFKLRKSNPNFLSNRASIKIKETIMRVGFFAFVAFAFVFITFACHVYEYYNQERWERSYRAFLMCIANHEVKGVSNTCSIKDRANLSVLELSLSSLFG---AGIAMSGWTWTSNTFKTW-----------KKLWHRVTTSVPLKK 510

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BLAST of Frizzled-5 vs. Ensembl Medaka
Match: ENSORLT00000013002.2 (pep primary_assembly:ASM223467v1:21:5638676:5644296:-1 gene:ENSORLG00000010376.2 transcript:ENSORLT00000013002.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 511.531 bits (1316), Expect = 6.995e-176
Identity = 266/530 (50.19%), Postives = 352/530 (66.42%), Query Frame = 2

Query:   92 QSFSISKPDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPE---DNACLRKDNKTRSN------KTTNFVSERPYLLKSKKCHCHCRSPLIIDSRDH---FNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDA-----IRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPCRTKKYQ----PEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLCCRKSLHHKVTCPTQL 1618
            QS   S    +   C PI + MCKGIGYNLTY+PN  NH + EE GLE+ QF  LV I CS DL  FLCSMY PICLP++   +P CRS+C  A+ GC+ +M+QYGF+WPE M+CE LP+   +  C+ +++   +       K+T  V  RP         C CR PLI   R+    F +V TG + NC + C  PYF   +++F++FW+G+W+ +C IST  T+ TF ID  RF+YPERPIIFL+ CYL +S+GY+IR+  GHE VAC +       I Y ++G   C++VFL +YFFGMASSIWWVVL+ TWFLAAG+KWGSEAI  Y+  +H  AW IP ++SI++L +SSVDGDPV+GICYVGN +  NL  FV+ PL+VYL  GT FLLAGF++L +IR  IK+ G +KTDKLE+LMIRI +F ++Y+VP   VV C +YE  +R  WE++  C C  ++ +    P+Y+VFMLKYFM LVVG T+G WIW+ KTL+SW     +  CC     HK T P  +
Sbjct:   10 QSLDPSLAASKDLVCEPITVPMCKGIGYNLTYMPNKFNHDTQEEVGLEVHQFWPLVRIRCSPDLLFFLCSMYTPICLPDYRKPLPPCRSVCERAKRGCSPLMSQYGFEWPERMSCEGLPQLGDETLCMDQNSSEATTSAPPFPKSTPKVRTRPPSPSQCDRECRCRDPLIPIKRESHALFGRVQTGPLPNCALPCHLPYFSADERAFTSFWVGLWSVLCFISTLTTVATFLIDMERFKYPERPIIFLAACYLFVSLGYIIRLVAGHERVACGAGGTSQLHILYDATGPALCTLVFLLVYFFGMASSIWWVVLSFTWFLAAGMKWGSEAIAGYSQYFHLAAWLIPSVKSILVLALSSVDGDPVAGICYVGNQSLENLRGFVLAPLVVYLFTGTLFLLAGFVSLFRIRSIIKQGG-TKTDKLERLMIRIGLFTVLYTVPATIVVACLVYEQHYRPSWERALACSCPLERQRSIRGPDYAVFMLKYFMCLVVGITSGVWIWSGKTLESWRSFVAR--CC-PCWAHKATAPPSM 535

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BLAST of Frizzled-5 vs. Ensembl Medaka
Match: fzd8a (frizzled class receptor 8a [Source:ZFIN;Acc:ZDB-GENE-000328-3])

HSP 1 Score: 493.426 bits (1269), Expect = 1.235e-168
Identity = 264/529 (49.91%), Postives = 344/529 (65.03%), Query Frame = 2

Query:  107 SKPDL----RPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLP----EDNACL---RKDNKTRS---NKTTNFVSERP------------YLLKSKKCH--CHCRSPLI-IDSRDH--FNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSD----AIRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPC-----RTKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLC 1573
            S+P L    +  TC  I + +CKGIGYN TY+PN  NH + +EAGLE+ QF  LVEI CS DL+ FLCSMY PICL ++   +P CRS+C  AR GC  +M QYGF WP+ M C+ LP     D  C+   R D+ T S   +K TN     P            Y   +  C   C C  P++ + +  H  +N+V TG ++NC M C +PYF   +++F+ FW+G+W+ +C +ST  T+ TF ID  RF+YPERPIIFLS CY+ +SVGY++R+  GHE VAC  D     I Y ++G   C+IVFL IYFFGMASSIWWV+L+ TWFLAAG+KWG+EAI  YA  +H  AW IP ++SI +L +SSVDGD V+GICYVGN N  NL  FV+ PL++YL +GT FLLAGF++L +IR  IK+ G +KTDKLEKLMIRI IF ++Y+VP   +V C  YE   R  WE ++ C          +  P+Y+VFMLKYFM L+VG T+G WIW+ KTLDSW + FC   C
Sbjct:    8 SRPGLLELSKEITCQGIAVPLCKGIGYNYTYMPNQFNHDTQDEAGLEVHQFWPLVEIQCSPDLKFFLCSMYTPICLEDYKKPLPPCRSVCERARAGCAPLMRQYGFPWPDRMRCDLLPVQGNPDTLCMDYNRNDSTTASPVLSKPTNHPGRSPKSKPGRAGAPGKYKPPAAPCEPGCRCLEPMVAVTTERHPLYNRVKTGQVTNCAMPCHNPYFTHDERAFTAFWIGLWSVLCFVSTFATVATFLIDMERFKYPERPIIFLSACYMFVSVGYIVRLIAGHEKVACNRDFDVEHIHYETTGPALCTIVFLLIYFFGMASSIWWVILSLTWFLAAGMKWGNEAIASYAQHFHLAAWLIPSMKSIAVLALSSVDGDSVAGICYVGNQNLDNLRGFVLAPLVIYLFIGTMFLLAGFVSLFRIRSVIKQGG-TKTDKLEKLMIRIGIFTVLYTVPATVIVACYFYEQHNRQDWEMTHNCSSCLMERERARSGPDYAVFMLKYFMCLLVGITSGVWIWSGKTLDSW-RTFCTRCC 534

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BLAST of Frizzled-5 vs. Ensembl Medaka
Match: ENSORLT00000002667.2 (pep primary_assembly:ASM223467v1:17:316235:318512:1 gene:ENSORLG00000002147.2 transcript:ENSORLT00000002667.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 483.026 bits (1242), Expect = 1.649e-164
Identity = 252/514 (49.03%), Postives = 345/514 (67.12%), Query Frame = 2

Query:  134 CIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPE----DNACLRKDNKTRS---------NKTTNFVSER--PYLLKSKKCH----------CHCRSPLI-IDSRDH--FNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACK----SDAIRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPCRTK--KYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLC 1573
            C  I + +CKGIGYN T++PN  +H + +EAGLE+ QF  LVEI CS DLR FLCSMY PICL ++   +P CR +C  A+ GC  +M QYGF WP+ M C+ LPE    D+ C+   ++T +         N+     ++R  PY       H          C CR+P++ + S  H   N+V TG I NC + C +PYF + +++F++FW+G+W+ +C IST  T+ TF ID  RF+YPERPIIFLS CY+ +SVGY++R+  GHE VAC     +  I Y ++G   C+IVFL IYFFGMASSIWWV+L+ TWFLAAG+KWG+EAI  Y+  +H  AW IP ++SI +L +SSVDGD V+G+CYVGN N  +L  FV+ PL++YL++GT FLLAGF++L +IR  IK+ G +KTDKLE+L+IRI +F ++Y+VP   +V C  YE   R  WE ++ C C T+  K +P Y+VFMLKYFM L+VG T+G WIW+ KTLD+W + FC+  C
Sbjct:   24 CQEISVPLCKGIGYNYTHMPNKFHHDTQDEAGLEVHQFWPLVEIKCSPDLRFFLCSMYTPICLEDYKKPLPPCRGVCERAKAGCAPLMRQYGFPWPDRMRCDLLPEQGNHDSLCMDYSSQTTTVSPALAKPTNRPLKPYNKRKGPYGRTFPGKHKPAGSPCEAACSCRAPMVPVSSEGHPLHNRVRTGQIVNCAVPCYNPYFTQEERTFTSFWIGLWSILCFISTFTTVATFLIDMERFKYPERPIIFLSACYMFVSVGYIVRLVAGHEEVACNMWNGAGYIHYETTGPALCTIVFLLIYFFGMASSIWWVILSLTWFLAAGMKWGNEAIGSYSQHFHLAAWLIPSMKSIAVLALSSVDGDSVAGVCYVGNQNLDSLRGFVLAPLVIYLVIGTMFLLAGFVSLFRIRSVIKQGG-TKTDKLERLIIRIGVFTVLYTVPATVIVACYFYEQHNRQAWEITHNCTCATEPSKQRPNYAVFMLKYFMCLLVGITSGAWIWSGKTLDTW-RTFCRRCC 535

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BLAST of Frizzled-5 vs. Ensembl Medaka
Match: fzd9b (frizzled class receptor 9 [Source:NCBI gene;Acc:101174936])

HSP 1 Score: 392.889 bits (1008), Expect = 3.639e-129
Identity = 229/548 (41.79%), Postives = 322/548 (58.76%), Query Frame = 2

Query:   62 FSWVLFRICGQSFSISKPDL---RPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNA----CLRK-DNKTRSNKTTNFVSERPYLLKSKKCHCHCRSPLIIDSR-----------DHFNKVVTGNISNCLMNCRSP----YFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDA-----IRYG--SSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWE-----------QSYTCPCRTKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLCCRK 1582
            F W L  +   S  +S  DL   RP+ C PI I MC GIGYNLT +PN ++H    EA +++Q+F  LV+  C   LR FLCS+YAP+C       IPACR +C  AR+ C  +M ++ + WP+ ++C KLP  N     C+   +N+TR+    +       L    +     R P    SR           D F  V      +C   C SP    Y+   DK F+  W+ +W+ +C +ST+ T+LTF ++  RFQYPERPIIFLS+CY++ S+ ++IR   G E +AC  +      I+ G  S+G   C+IVFL +Y+FGMASSIWWV+LT TWFLAAG KWG EAI  +++ +H  AW IP +++I+ILTM  V GD ++G+CYVG+++   L  FV+IPL  YL++GT F+L GF+AL  IRK +K +G + T+KLEKLM++I I+ I+Y+VP   V+ C  YE +  D W+            S+   C  +   P  +VFMLK FM+LVVG T+G W+W+ KTL +W       LC RK
Sbjct:   14 FLWALLPVSASSLEMSFYDLERDRPAKCEPIVIPMCVGIGYNLTRMPNFMDHDDQAEAAIKLQEFAPLVDYGCDVHLRFFLCSLYAPMCTDKVSTSIPACRPMCEQARDKCAPIMKKFSYTWPDSLDCSKLPTRNDPNALCMEAPENETRTEGKKDKKKGEGMLPVPPRP----RQPDTPSSRLPGSGNSCENPDKFQFVEKSQ--SCAPRC-SPAVDVYWSRQDKDFAFIWMTVWSILCFVSTAFTVLTFLLEPHRFQYPERPIIFLSMCYMVYSLAFIIRSVAGAENIACDREHGELYIIQEGLESTG---CTIVFLILYYFGMASSIWWVILTLTWFLAAGKKWGHEAIEAHSNYFHMAAWGIPALKTIVILTMRKVAGDELTGLCYVGSMDSGALTGFVLIPLSCYLIIGTSFILTGFVALFHIRKVMKTEG-TNTEKLEKLMVKIGIYSILYTVPATCVIVCYFYERLNMDYWKLRGLQEECDSFSSHNSKCSLETSVPTVAVFMLKIFMSLVVGITSGVWVWSSKTLQTWQG-----LCSRK 545

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BLAST of Frizzled-5 vs. Ensembl Medaka
Match: fzd7b (frizzled class receptor 7b [Source:ZFIN;Acc:ZDB-GENE-990415-229])

HSP 1 Score: 380.948 bits (977), Expect = 4.690e-125
Identity = 214/515 (41.55%), Postives = 306/515 (59.42%), Query Frame = 2

Query:  134 CIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNA---CLRKDNKTRSN------KTTNFVSERPYLLKSKKCHCH-----CRSPLIIDSRDHFNKVVTGNISNCLMNCRSP------YFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVAC----KSDAIRYGSSGAVP--CSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSY---TC-----PCRTKKYQ---PEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKL 1567
            C PI I +C  I YN T +PN L H + E+AGLE+ QF  LV++ CS +L+ FLCSMYAP+C       IP CRSLC  AR+GC  +MN++GF+WPE ++CE  P +     C+ ++     +           V+  P    +     H        PL ++   +      G + +C   C         YF E +  F   W+GIW+ +C +ST  T+LT+ +D  RF+YPERPIIFLS CY +++V Y     L  + V C    K +  R  + G     C+I+F+ +YFFGMASSIWWV+L+ TWFL+AG+KWG EAI   +  +H  AW +P I++I IL M  VDGD ++G+C+VG  N   L  FV+ PL VYL +GT FLLAGF++L +IR  +K  G +KT+KLEKLM+RI +F ++Y+VP   V+ C  YE  FR+ WE+++   TC     PC    +    P+++VFM+KY M ++VG T+GFW+W+ KTL SW + + +L
Sbjct:   30 CQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSTELKFFLCSMYAPVCT-VLEQAIPPCRSLCERARQGCEALMNKFGFQWPERLHCEAFPVNGGSEICVGQNTSEPGSPSSSSPHVPELVTVPPNRFPNPPQPPHNSYHQFSCPLQLEVPSYLGYRFMG-VKDCGAPCEPTKPSGIMYFREDEVKFGRLWVGIWSILCCVSTLFTVLTYLVDMRRFRYPERPIIFLSGCYFMVAVAYAAGFFL-EDKVVCVDKFKGEGFRTVAQGTKKEGCTILFMVLYFFGMASSIWWVILSLTWFLSAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILAMGQVDGDVLTGVCFVGIFNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDG-TKTEKLEKLMVRIGVFSVLYTVPATIVIACYFYEQAFREHWERTWHMQTCKRFAVPCPVHNFAPMTPDFTVFMIKYLMTMIVGITSGFWVWSGKTLQSWRRFYKRL 540

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BLAST of Frizzled-5 vs. Planmine SMEST
Match: SMESG000031852.1 (SMESG000031852.1)

HSP 1 Score: 1176.77 bits (3043), Expect = 0.000e+0
Identity = 589/590 (99.83%), Postives = 589/590 (99.83%), Query Frame = 2

Query:   32 MTIAIGISLLFSWVLFRICGQSFSISKPDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNACLRKDNKTRSNKTTNFVSERPYLLKSKKCHCHCRSPLIIDSRDHFNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDAIRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPCRTKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLCCRKSLHHKVTCPTQLDKPLCKPETLSTKALLYSLNSSYNVNDRQILSASNMIRSGITLSNSPDSETLTKLISLTHV 1801
            MTIAIGISLLFSWVLFRICGQSFSISKPDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNACLRKDNKTRSNKT NFVSERPYLLKSKKCHCHCRSPLIIDSRDHFNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDAIRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYLLVGTGFLLAGFLALMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPCRTKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLCCRKSLHHKVTCPTQLDKPLCKPETLSTKALLYSLNSSYNVNDRQILSASNMIRSGITLSNSPDSETLTKLISLTHV
Sbjct:    1 MTIAIGISLLFSWVLFRICGQSFSISKPDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNACLRKDNKTRSNKTANFVSERPYLLKSKKCHCHCRSPLIIDSRDHFNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDAIRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYLLVGTGFLLAGFLALMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPCRTKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLCCRKSLHHKVTCPTQLDKPLCKPETLSTKALLYSLNSSYNVNDRQILSASNMIRSGITLSNSPDSETLTKLISLTHV 590

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BLAST of Frizzled-5 vs. Planmine SMEST
Match: SMESG000005043.1 (SMESG000005043.1)

HSP 1 Score: 620.928 bits (1600), Expect = 0.000e+0
Identity = 303/519 (58.38%), Postives = 388/519 (74.76%), Query Frame = 2

Query:  107 SKPDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNACLRKDNKTRSNKTTNFVSERPYLLKSKKCHCHCRSPLIIDSRDHFNKVVTGNISNCLMNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDAIRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPC-RTKKYQ-----PEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKL---LCCRKSLHHKVTCPTQLDKPLCK 1636
            ++ + RP+ C+PI I MCK IGYNLTY+PN+ +H + EEAGL + QF  LVEI CS++LRLFLCS+YAPICLPNWP  I ACRS+C SAR+GC  VMN YGFKWP+ M+C+KL E+ ACL+KD K         V++ P    SK C C CRSP I D++  FN V+TG ++NC  +C S  F   DKSF TFWLG+WA +C +S++ T+LTF +D+SRF+YPERPI+FLS CY+++S+GY+IRVA+GHE +AC  D +RYG++G   CSIVFL IYFFGMA+S+WWV+LT TWFL+AGLKWGSEAI  Y++I+HF AWF+ G++SI+ LT+ ++DGDPV GICY+GN N  NL  F+I+PL VYLL+G+ FLL+GF+AL+ IRKTI+ KGESKTDKLEKLM+RI IFG++YSVP   V+ C +YE   R+ WE+S  C C R  K Q     PEYSVFMLKYFM LVVG T+GFWIWT KTLDSW   F +L   +C +   H K     + + PLC+
Sbjct:   50 NQENFRPNKCVPIAIPMCKNIGYNLTYMPNEFHHETQEEAGLVVHQFYPLVEIACSDNLRLFLCSLYAPICLPNWPKPIQACRSVCESARDGCAPVMNTYGFKWPKSMDCDKLTENQACLKKDTKN--------VTKPP----SKGCECKCRSPYIYDNKPQFNSVITGGVANCFQSCHSANFVSIDKSFVTFWLGLWAVLCCLSSTATVLTFLLDRSRFKYPERPIVFLSGCYMMVSIGYIIRVAVGHELIACDGDKLRYGTTGPARCSIVFLLIYFFGMAASVWWVILTITWFLSAGLKWGSEAISKYSEIFHFLAWFLSGVKSILALTLVAIDGDPVGGICYIGNTNSLNLKLFLIVPLTVYLLIGSCFLLSGFIALISIRKTIRAKGESKTDKLEKLMMRIGIFGLLYSVPAAVVIGCHLYEVKNREFWEKSNNCYCNRNIKSQENFSKPEYSVFMLKYFMCLVVGITSGFWIWTSKTLDSWHNAFRRLSQSICGQSDKHTKQFPGNEQETPLCQ 556

[Close]

BLAST of Frizzled-5 vs. Planmine SMEST
Match: SMESG000035834.1 (SMESG000035834.1)

HSP 1 Score: 494.582 bits (1272), Expect = 1.097e-166
Identity = 257/532 (48.31%), Postives = 341/532 (64.10%), Query Frame = 2

Query:  134 CIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLP-----EDNACLRK---------------------DNKTRSNKTTNFVSERPYLLKSKK-----CHCHCRSPLIIDS---RDHFNKVVTGNISNCLMNCRSPYFG-EFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKS---------DAIRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPC-RTKKYQ-----PEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLCCR 1579
            C  I+I MCK I YN+T +PN  NH + +EAG E  QF  LV+I CSEDL+ FLCS+Y PICL  +   +P CRS+C   ++GC  ++ +Y FKWPE MNC++ P     E   C+ K                     D  +R     N ++E  Y L  +      C C CR PLI  +   + HFN+V T  + NC   C+SP+F  E D+ F  FWLG+W  +C++ST   + TF ID  R++YPERPIIF+SICY ++S+G+LIR+ +GHE +AC S           +RYG SG   C+IVFL IY+FGMA+S+WWV+LT TWFLAAGLKWGSEAI  Y+ IYHF AWF+PGI+SI+ LTMS+VDGDPVSGICYVGN + +NL+ FV+ PL+VYL +GT  L++GF +L +IR  IK +   KT+KLEKLMIRI +F ++Y+ P   +V C IYE   R  W Q+ +C C  + ++Q     P YSVFM KYFM + VG T+GFWIW+ KT+ SW     K++C R
Sbjct:   43 CEIIKIPMCKDIHYNMTMMPNMFNHENQDEAGFEAHQFYPLVQIKCSEDLQFFLCSIYTPICLKQYVKSLPPCRSVCERVKKGCDPLLQKYTFKWPEKMNCDQFPVYNNPEKILCMEKNLSTASTTLASVVTLAPKEQNDANSRQVAEQNLLNEVSYQLTRQYNSRVFCQCSCRKPLIDIAEINKAHFNRVSTLGMFNCAQGCKSPFFSSESDQKFIGFWLGLWTIICLLSTFSIVATFSIDPGRYRYPERPIIFMSICYFMVSLGFLIRIVMGHEDLACDSIKAKDGSSLSLLRYGGSGPAHCTIVFLLIYYFGMAASLWWVLLTITWFLAAGLKWGSEAISKYSQIYHFLAWFLPGIKSIVALTMSAVDGDPVSGICYVGNTSDFNLILFVLSPLLVYLTIGTLVLISGFASLFRIRSIIKLQTGGKTEKLEKLMIRIGVFSVLYTAPAAVIVACIIYELQNRAEWYQNLSCDCFDSNRHQLNLPRPSYSVFMFKYFMFMGVGMTSGFWIWSKKTILSW-----KMVCYR 569

[Close]

BLAST of Frizzled-5 vs. Planmine SMEST
Match: SMESG000035834.1 (SMESG000035834.1)

HSP 1 Score: 479.174 bits (1232), Expect = 1.805e-161
Identity = 248/517 (47.97%), Postives = 331/517 (64.02%), Query Frame = 2

Query:  179 LTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLP-----EDNACLRK---------------------DNKTRSNKTTNFVSERPYLLKSKK-----CHCHCRSPLIIDS---RDHFNKVVTGNISNCLMNCRSPYFG-EFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKS---------DAIRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPC-RTKKYQ-----PEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLLCCR 1579
            +T +PN  NH + +EAG E  QF  LV+I CSEDL+ FLCS+Y PICL  +   +P CRS+C   ++GC  ++ +Y FKWPE MNC++ P     E   C+ K                     D  +R     N ++E  Y L  +      C C CR PLI  +   + HFN+V T  + NC   C+SP+F  E D+ F  FWLG+W  +C++ST   + TF ID  R++YPERPIIF+SICY ++S+G+LIR+ +GHE +AC S           +RYG SG   C+IVFL IY+FGMA+S+WWV+LT TWFLAAGLKWGSEAI  Y+ IYHF AWF+PGI+SI+ LTMS+VDGDPVSGICYVGN + +NL+ FV+ PL+VYL +GT  L++GF +L +IR  IK +   KT+KLEKLMIRI +F ++Y+ P   +V C IYE   R  W Q+ +C C  + ++Q     P YSVFM KYFM + VG T+GFWIW+ KT+ SW     K++C R
Sbjct:    1 MTMMPNMFNHENQDEAGFEAHQFYPLVQIKCSEDLQFFLCSIYTPICLKQYVKSLPPCRSVCERVKKGCDPLLQKYTFKWPEKMNCDQFPVYNNPEKILCMEKNLSTASTTLASVVTLAPKEQNDANSRQVAEQNLLNEVSYQLTRQYNSRVFCQCSCRKPLIDIAEINKAHFNRVSTLGMFNCAQGCKSPFFSSESDQKFIGFWLGLWTIICLLSTFSIVATFSIDPGRYRYPERPIIFMSICYFMVSLGFLIRIVMGHEDLACDSIKAKDGSSLSLLRYGGSGPAHCTIVFLLIYYFGMAASLWWVLLTITWFLAAGLKWGSEAISKYSQIYHFLAWFLPGIKSIVALTMSAVDGDPVSGICYVGNTSDFNLILFVLSPLLVYLTIGTLVLISGFASLFRIRSIIKLQTGGKTEKLEKLMIRIGVFSVLYTAPAAVIVACIIYELQNRAEWYQNLSCDCFDSNRHQLNLPRPSYSVFMFKYFMFMGVGMTSGFWIWSKKTILSW-----KMVCYR 512

[Close]

BLAST of Frizzled-5 vs. Planmine SMEST
Match: SMESG000040115.1 (SMESG000040115.1)

HSP 1 Score: 319.701 bits (818), Expect = 5.465e-101
Identity = 198/501 (39.52%), Postives = 289/501 (57.68%), Query Frame = 2

Query:  179 LTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNACLRKDNKTRSNKTTNFVSERPYLLKSKKCHCHCRSPLIIDSRDHFNKVVTGNISNCLMNCRSPYFGEFD-KSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDAIRYGSSGAVP-----------CSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYXXXXXXXXXXXXXXXMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTC--PCRTKKY------------------------QPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKL 1567
            +T  PN + H++ +EA LEI ++  L+ I C   L+LFLCS+Y P+C       +P CRSLC+  ++ C  ++ ++ FKWP+ M+C+  PE+N C+R DN+T      N          S  C    + P+  D +   ++     I +C + C   YF E + + F+  W+ +W+ +C+ ST  T+LTF ID  RFQYPERPIIFLS CYL++ + Y+    L ++ VAC        S+G  P           C I+F+ +YFF MAS+IWWVVLT TW+LAA   W  E+I   +  +HF AW IP  ++I IL +S VDGDP++G+C+ G  +   L  F+I PL +YLL+GTGFL+AGF+++ +IR  IK  G SKTDKLEKL+ RI IF ++Y VP + V+ C  +E +    W Q +     CR+ +Y                        +PE+ +FM+KY M+L+VG T+G WIW+ KTL SW   F +L
Sbjct:    1 MTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIM-KKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPENNLCIR-DNQTEKESAPNV---------SLSCPKSLQIPVSYDFKIRLSQ--NSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFL-NDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGG-SKTDKLEKLITRIGIFSVLYVVPAVVVIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRL 486

The following BLAST results are available for this feature:

BLAST of Frizzled-5 vs. Ensembl Human
BLAST of Frizzled-5 vs. Ensembl Celegans
BLAST of Frizzled-5 vs. Ensembl Fly
BLAST of Frizzled-5 vs. Ensembl Zebrafish
BLAST of Frizzled-5 vs. Ensembl Xenopus
BLAST of Frizzled-5 vs. Ensembl Mouse
BLAST of Frizzled-5 vs. UniProt/SwissProt
BLAST of Frizzled-5 vs. TrEMBL
BLAST of Frizzled-5 vs. Ensembl Cavefish
BLAST of Frizzled-5 vs. Ensembl Sea Lamprey
BLAST of Frizzled-5 vs. Ensembl Yeast
BLAST of Frizzled-5 vs. Ensembl Nematostella
BLAST of Frizzled-5 vs. Ensembl Medaka
BLAST of Frizzled-5 vs. Planmine SMEST

BLAST of Frizzled-5 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
FZD5	7.552e-172	50.47	frizzled class receptor 5 [Source:HGNC Symbol;Acc:...	[more]
FZD10	2.073e-135	43.69	frizzled class receptor 10 [Source:HGNC Symbol;Acc...	[more]
FZD7	3.483e-125	41.50	frizzled class receptor 7 [Source:HGNC Symbol;Acc:...	[more]
FZD1	6.190e-125	42.09	frizzled class receptor 1 [Source:HGNC Symbol;Acc:...	[more]
FZD2	1.356e-122	40.04	frizzled class receptor 2 [Source:HGNC Symbol;Acc:...	[more]

BLAST of Frizzled-5 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
cfz-2	3.643e-117	37.75	Frizzled-2 [Source:UniProtKB/Swiss-Prot;Acc:G5ECQ...	[more]
mom-5	1.391e-97	36.24	pep chromosome:WBcel235:I:9965580:9970037:1 gene:W...	[more]
mom-5	2.837e-96	36.38	pep chromosome:WBcel235:I:9965580:9969413:1 gene:W...	[more]
lin-17	6.413e-66	28.71	Transmembrane receptor LIN-17 [Source:UniProtKB/T...	[more]
lin-17	6.413e-66	28.71	Transmembrane receptor LIN-17 [Source:UniProtKB/T...	[more]

BLAST of Frizzled-5 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
fz2	4.934e-153	43.89	gene:FBgn0016797 transcript:FBtr0112890	[more]
fz2	4.934e-153	43.89	gene:FBgn0016797 transcript:FBtr0075029	[more]
fz2	4.934e-153	43.89	gene:FBgn0016797 transcript:FBtr0332735	[more]
fz2	4.934e-153	43.89	gene:FBgn0016797 transcript:FBtr0330194	[more]
fz2	4.934e-153	43.89	gene:FBgn0016797 transcript:FBtr0075028	[more]

BLAST of Frizzled-5 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
fzd5	3.100e-174	49.08	frizzled class receptor 5 [Source:ZFIN;Acc:ZDB-GEN...	[more]
fzd8b	4.476e-171	48.92	frizzled class receptor 8b [Source:ZFIN;Acc:ZDB-GE...	[more]
fzd8b	7.699e-171	48.92	frizzled class receptor 8b [Source:ZFIN;Acc:ZDB-GE...	[more]
fzd8a	1.720e-170	51.17	frizzled class receptor 8a [Source:ZFIN;Acc:ZDB-GE...	[more]
fzd9b	6.258e-130	41.48	frizzled class receptor 9b [Source:ZFIN;Acc:ZDB-GE...	[more]

BLAST of Frizzled-5 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
zdhhc9	0.000e+0	50.84	zinc finger DHHC-type containing 9 [Source:Xenbase...	[more]
fzd8	1.441e-164	49.23	frizzled class receptor 8 [Source:NCBI gene;Acc:10...	[more]
bdh2	1.544e-129	43.63	3-hydroxybutyrate dehydrogenase 2 [Source:Xenbase;...	[more]
ntrk1	2.496e-126	41.19	neurotrophic receptor tyrosine kinase 1 [Source:Xe...	[more]
FZD9	1.211e-124	42.58	frizzled class receptor 9 [Source:NCBI gene;Acc:10...	[more]

BLAST of Frizzled-5 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Fzd5	1.232e-170	49.25	frizzled class receptor 5 [Source:MGI Symbol;Acc:M...	[more]
Fzd5	1.232e-170	49.25	frizzled class receptor 5 [Source:MGI Symbol;Acc:M...	[more]
Fzd8	1.027e-157	42.76	frizzled class receptor 8 [Source:MGI Symbol;Acc:M...	[more]
Fzd10	3.953e-130	42.34	frizzled class receptor 10 [Source:MGI Symbol;Acc:...	[more]
Fzd7	1.436e-126	41.84	frizzled class receptor 7 [Source:MGI Symbol;Acc:M...	[more]

BLAST of Frizzled-5 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P58421\|FZD5_XENLA	5.023e-177	50.47	Frizzled-5 OS=Xenopus laevis OX=8355 GN=fzd5 PE=2 ...	[more]
sp\|Q13467\|FZD5_HUMAN	3.627e-171	50.47	Frizzled-5 OS=Homo sapiens OX=9606 GN=FZD5 PE=1 SV...	[more]
sp\|Q8CHL0\|FZD5_RAT	8.249e-170	49.06	Frizzled-5 OS=Rattus norvegicus OX=10116 GN=Fzd5 P...	[more]
sp\|Q9EQD0\|FZD5_MOUSE	8.615e-170	49.25	Frizzled-5 OS=Mus musculus OX=10090 GN=Fzd5 PE=1 S...	[more]
sp\|O93274\|FZD8_XENLA	1.010e-165	49.23	Frizzled-8 OS=Xenopus laevis OX=8355 GN=fzd8 PE=1 ...	[more]

BLAST of Frizzled-5 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
T1E0Z7	0.000e+0	99.83	Fzd-5/8-1 OS=Schmidtea mediterranea OX=79327 PE=2 ...	[more]
T1DF88	0.000e+0	70.44	Fzd-5/8-1 OS=Dendrocoelum lacteum OX=27895 PE=2 SV...	[more]
T1DBJ2	0.000e+0	58.38	Fzd-5/8-4 OS=Schmidtea mediterranea OX=79327 PE=2 ...	[more]
T1E109	0.000e+0	57.55	Fzd-5/8-4 OS=Dendrocoelum lacteum OX=27895 PE=2 SV...	[more]
A0A2T7PZY2	0.000e+0	52.29	Uncharacterized protein OS=Pomacea canaliculata OX...	[more]

BLAST of Frizzled-5 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSAMXT00000026985.2	1.139e-176	51.08	pep primary_assembly:Astyanax_mexicanus-2.0:19:270...	[more]
fzd8a	1.055e-149	46.71	frizzled class receptor 8a [Source:ZFIN;Acc:ZDB-GE...	[more]
fzd7b	2.787e-128	43.00	frizzled class receptor 7b [Source:ZFIN;Acc:ZDB-GE...	[more]
fzd9b	4.014e-128	41.97	frizzled-9 [Source:NCBI gene;Acc:103027133]	[more]
fzd9a	5.586e-127	40.51	frizzled class receptor 9a [Source:ZFIN;Acc:ZDB-GE...	[more]

BLAST of Frizzled-5 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000011009.1	5.044e-166	47.06	pep scaffold:Pmarinus_7.0:GL485859:2701:4509:1 gen...	[more]
fzd2	1.313e-127	42.56	frizzled class receptor 2 [Source:ZFIN;Acc:ZDB-GEN...	[more]
fzd8a	4.698e-112	48.21	frizzled class receptor 8a [Source:ZFIN;Acc:ZDB-GE...	[more]
fzd7a	3.411e-81	45.62	frizzled class receptor 7a [Source:ZFIN;Acc:ZDB-GE...	[more]
fzd3b	3.479e-63	37.35	frizzled class receptor 3b [Source:ZFIN;Acc:ZDB-GE...	[more]

BLAST of Frizzled-5 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Frizzled-5 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO42932	3.915e-165	50.81	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO38567	1.489e-129	42.62	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO35751	5.649e-126	40.11	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO30865	4.373e-105	38.83	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO40119	3.379e-36	25.05	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Frizzled-5 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSORLT00000013002.2	6.995e-176	50.19	pep primary_assembly:ASM223467v1:21:5638676:564429...	[more]
fzd8a	1.235e-168	49.91	frizzled class receptor 8a [Source:ZFIN;Acc:ZDB-GE...	[more]
ENSORLT00000002667.2	1.649e-164	49.03	pep primary_assembly:ASM223467v1:17:316235:318512:...	[more]
fzd9b	3.639e-129	41.79	frizzled class receptor 9 [Source:NCBI gene;Acc:10...	[more]
fzd7b	4.690e-125	41.55	frizzled class receptor 7b [Source:ZFIN;Acc:ZDB-GE...	[more]

BLAST of Frizzled-5 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000031852.1	0.000e+0	99.83	SMESG000031852.1	[more]
SMESG000005043.1	0.000e+0	58.38	SMESG000005043.1	[more]
SMESG000035834.1	1.097e-166	48.31	SMESG000035834.1	[more]
SMESG000035834.1	1.805e-161	47.97	SMESG000035834.1	[more]
SMESG000040115.1	5.465e-101	39.52	SMESG000040115.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30020953 ID=SMED30020953|Name=Frizzled-5|organism=Schmidtea mediterranea sexual|type=transcript|length=1862bp
CGGTAATTAATAAGAGCCAACTGGTGAATTTATGACAATCGCAATTGGGA
TTTCGTTGTTATTTTCGTGGGTTTTATTTCGAATTTGTGGTCAATCGTTT
TCAATAAGCAAACCCGATTTGAGACCGTCGACTTGTATTCCAATTGAAAT
TTCAATGTGCAAAGGAATCGGATATAATTTGACGTATATTCCAAACGATT
TAAATCATGCTTCTTTGGAAGAAGCTGGATTAGAGATTCAGCAGTTCAAT
GCTCTCGTGGAAATCAATTGCTCAGAAGACCTTAGGTTATTTTTGTGTAG
CATGTATGCTCCGATTTGTCTTCCGAATTGGCCAAATCGAATTCCAGCTT
GTCGGTCTTTATGCATCAGCGCTAGAGAAGGTTGCACTCGTGTTATGAAC
CAATATGGTTTCAAATGGCCCGAAGGAATGAACTGTGAAAAGTTACCAGA
AGATAATGCTTGTCTGCGAAAGGATAACAAAACAAGATCGAATAAAACCA
CCAATTTCGTATCAGAAAGACCATATTTATTGAAATCTAAAAAATGTCAC
TGTCATTGTAGATCACCCTTGATAATTGACTCGAGAGACCATTTCAATAA
AGTTGTAACCGGAAATATCAGCAATTGTCTCATGAATTGTCGTTCTCCTT
ATTTTGGCGAATTTGATAAGAGTTTCTCTACATTTTGGTTAGGGATTTGG
GCTTGTGTTTGCATCATTTCAACGTCAGTTACAATATTAACATTCTGCAT
TGATAAATCAAGATTTCAATACCCCGAACGACCGATTATTTTTCTTTCCA
TTTGTTACTTGTTGATGTCAGTTGGATATTTGATTAGAGTGGCTCTAGGG
CATGAAGCAGTAGCTTGCAAATCTGATGCCATCCGTTATGGGTCATCGGG
GGCTGTTCCTTGTAGCATTGTATTTCTCTTTATTTACTTTTTCGGAATGG
CTTCATCTATTTGGTGGGTTGTGTTAACTGCCACTTGGTTTTTGGCGGCA
GGACTCAAATGGGGCTCAGAAGCAATTTTGATGTACGCTGATATATATCA
TTTTTTTGCCTGGTTTATTCCGGGAATACAGAGCATTATTATTCTCACTA
TGAGCTCAGTGGATGGAGACCCAGTTTCGGGGATATGTTATGTTGGAAAT
TTAAATAAATACAATTTGTTATTCTTCGTAATCATTCCTCTTATTGTCTA
TCTTTTGGTTGGCACAGGGTTTTTGTTGGCAGGTTTTCTGGCATTAATGA
AAATTCGAAAAACCATCAAAGAGAAAGGAGAGTCAAAAACAGATAAATTG
GAAAAACTTATGATCAGAATCAGTATTTTCGGAATCGTCTATTCTGTGCC
AACGATGACTGTGGTTTTTTGTAGCATTTATGAATTTATTTTCCGAGATT
TATGGGAGCAGTCTTATACTTGTCCGTGTAGAACAAAGAAATATCAACCA
GAATATTCAGTTTTCATGCTGAAATATTTCATGAATCTCGTCGTCGGGAC
GACTGCCGGGTTCTGGATATGGACTCCTAAAACTCTGGATTCGTGGAGTA
AAGTGTTTTGTAAATTACTTTGTTGCCGGAAAAGCTTGCATCACAAAGTC
ACTTGTCCAACTCAATTAGATAAACCCTTGTGCAAACCTGAAACTCTCAG
TACTAAAGCTCTTTTGTATAGCTTAAATAGCAGTTACAATGTCAATGATA
GGCAAATTCTCTCGGCTTCGAATATGATTAGATCGGGTATAACCCTTTCG
AATTCTCCGGATTCTGAGACTCTTACAAAACTGATCTCATTAACTCATGT
GTGAAATCGTTATTTAGTCACTTTTTTACTATTTTTGTGAATATTGTATT
TATTGATTGTGC

protein sequence of SMED30020953-orf-1

>SMED30020953-orf-1 ID=SMED30020953-orf-1|Name=SMED30020953-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=591bp
MTIAIGISLLFSWVLFRICGQSFSISKPDLRPSTCIPIEISMCKGIGYNL
TYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNW
PNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNACLRKDNK
TRSNKTTNFVSERPYLLKSKKCHCHCRSPLIIDSRDHFNKVVTGNISNCL
MNCRSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPER
PIIFLSICYLLMSVGYLIRVALGHEAVACKSDAIRYGSSGAVPCSIVFLF
IYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQ
SIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYLLVGTGFLLA
GFLALMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIY
EFIFRDLWEQSYTCPCRTKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPK
TLDSWSKVFCKLLCCRKSLHHKVTCPTQLDKPLCKPETLSTKALLYSLNS
SYNVNDRQILSASNMIRSGITLSNSPDSETLTKLISLTHV*

Aliases

The feature 'Frizzled-5' has the following synonyms


Synonym
fzdP-1

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **cellular component**
Term	Definition
GO:0000139	Golgi membrane
GO:0005794	Golgi apparatus
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Vocabulary: **molecular function**
Term	Definition
GO:0004930	G-protein coupled receptor activity
GO:0005515	protein binding
GO:0004888	transmembrane signaling receptor activity
GO:0042813	Wnt-activated receptor activity

Vocabulary: **biological process**
Term	Definition
GO:0007165	signal transduction
GO:0007186	G-protein coupled receptor signaling pathway
GO:0042127	regulation of cell proliferation
GO:0043010	camera-type eye development
GO:0045595	regulation of cell differentiation
GO:0048666	neuron development
GO:0007166	cell surface receptor signaling pathway
GO:0007275	multicellular organism development
GO:0016055	Wnt signaling pathway

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000017	photoreceptor neuron
PLANA:0000099	neuron
PLANA:0000418	head

Vocabulary: **INTERPRO**
Term	Definition
IPR036790	Frizzled_dom_sf
IPR015526	Frizzled/SFRP
IPR000539	Frizzled/Smoothened_TM
IPR020067	Frizzled_dom
IPR017981	GPCR_2-like

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR000539	Frizzled/Smoothened, transmembrane domain	PRINTS	PR00489	FRIZZLED	coord: 247..269 score: 56.87 coord: 296..320 score: 63.2 coord: 219..241 score: 41.22 coord: 384..406 score: 49.22 coord: 426..447 score: 42.91 coord: 477..497 score: 54.1 coord: 339..362 score: 42.5
IPR000539	Frizzled/Smoothened, transmembrane domain	SMART	SM01330	Frizzled_2	coord: 206..515 e-value: 3.8E-168 score: 574.6
IPR000539	Frizzled/Smoothened, transmembrane domain	PFAM	PF01534	Frizzled	coord: 207..511 e-value: 1.6E-122 score: 408.6
IPR020067	Frizzled domain	SMART	SM00063	FRI_4	coord: 34..149 e-value: 1.8E-53 score: 193.6
IPR020067	Frizzled domain	PFAM	PF01392	Fz	coord: 35..142 e-value: 2.6E-33 score: 115.0
IPR020067	Frizzled domain	PROSITE	PS50038	FZ	coord: 30..147 score: 25.886
IPR036790	Frizzled cysteine-rich domain superfamily	GENE3D	G3DSA:1.10.2000.10		coord: 30..154 e-value: 3.4E-41 score: 142.4
IPR036790	Frizzled cysteine-rich domain superfamily	SUPERFAMILY	SSF63501	Frizzled cysteine-rich domain	coord: 32..142
None	No IPR available	GENE3D	G3DSA:1.20.1070.10		coord: 173..514 e-value: 3.1E-129 score: 432.8
None	No IPR available	PANTHER	PTHR11309:SF136	FRIZZLED-5	coord: 14..520
None	No IPR available	CDD	cd15035	7tmF_FZD5_FZD8-like	coord: 206..510 e-value: 1.57458E-170 score: 484.474
None	No IPR available	SIGNALP_EUK	SignalP-noTM	SignalP-noTM	coord: 1..20 score: 0.737
None	No IPR available	TMHMM	TMhelix		coord: 431..453
None	No IPR available	TMHMM	TMhelix		coord: 251..273
None	No IPR available	TMHMM	TMhelix		coord: 338..360
None	No IPR available	TMHMM	TMhelix		coord: 296..325
None	No IPR available	TMHMM	TMhelix		coord: 217..239
None	No IPR available	TMHMM	TMhelix		coord: 380..402
None	No IPR available	TMHMM	TMhelix		coord: 475..497
IPR015526	Frizzled/secreted frizzled-related protein	PANTHER	PTHR11309	FRIZZLED	coord: 14..520
IPR017981	GPCR, family 2-like	PROSITE	PS50261	G_PROTEIN_RECEP_F2_4	coord: 216..504 score: 35.855

Main menu

Frizzled-5

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Owlery

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