ATP-dependent RNA helicase DHX8
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30020946 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 5
Homology
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Human
Match: DHX8 (DEAH-box helicase 8 [Source:NCBI gene;Acc:1659]) HSP 1 Score: 530.791 bits (1366), Expect = 2.295e-173 Identity = 271/614 (44.14%), Postives = 387/614 (63.03%), Query Frame = 3 Query: 186 LPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNL--------ESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYR-AMKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEF 1991 LPI + K+ +++ V +NQI+I+ G TGSGKTTQI QYL EAG + IG TQPRR+AA+++A RV++E CLG EVGY +RF +S T IKYMTDG+LL +CL DP L +Y ++M+DEAHERT+ TDVL GL+K +R D+K+++TSAT+ KFS YF AP+ + G+ Y V+I+Y EP + + ++Q IH GDIL+FLTGQE+I+ C+ L + L +LP+Y AL + Q IF PA PG RKV+++TNIAETS+TIDGI +V+D G+VKQ +++S++GID L ISQ QA QR GRAGRT G CYRLYTE YR M PEI R NL T L + +GI D +SF F+D+P ETL + +L L +D+ +T LG+ + +FP+EP + K L S C E++TI++M+S +NVF RPK +D K KF +EGD L Y +W N+ S WCY+NF+ +++ + +R Q++G++ R + + V ++K++ F++N + + Y ++QQV+Y+HPSS L N ++Y+E+V T K YMR + T+ L EF Sbjct: 565 LPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRRVAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLDASLITVMQ-IHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKSTV-RVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTIDPRWLVEF 1176
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Human
Match: DHX8 (DEAH-box helicase 8 [Source:NCBI gene;Acc:1659]) HSP 1 Score: 530.791 bits (1366), Expect = 2.295e-173 Identity = 271/614 (44.14%), Postives = 387/614 (63.03%), Query Frame = 3 Query: 186 LPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNL--------ESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYR-AMKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEF 1991 LPI + K+ +++ V +NQI+I+ G TGSGKTTQI QYL EAG + IG TQPRR+AA+++A RV++E CLG EVGY +RF +S T IKYMTDG+LL +CL DP L +Y ++M+DEAHERT+ TDVL GL+K +R D+K+++TSAT+ KFS YF AP+ + G+ Y V+I+Y EP + + ++Q IH GDIL+FLTGQE+I+ C+ L + L +LP+Y AL + Q IF PA PG RKV+++TNIAETS+TIDGI +V+D G+VKQ +++S++GID L ISQ QA QR GRAGRT G CYRLYTE YR M PEI R NL T L + +GI D +SF F+D+P ETL + +L L +D+ +T LG+ + +FP+EP + K L S C E++TI++M+S +NVF RPK +D K KF +EGD L Y +W N+ S WCY+NF+ +++ + +R Q++G++ R + + V ++K++ F++N + + Y ++QQV+Y+HPSS L N ++Y+E+V T K YMR + T+ L EF Sbjct: 565 LPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRRVAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLDASLITVMQ-IHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKSTV-RVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTIDPRWLVEF 1176
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Human
Match: DHX8 (DEAH-box helicase 8 [Source:NCBI gene;Acc:1659]) HSP 1 Score: 509.605 bits (1311), Expect = 1.253e-165 Identity = 259/581 (44.58%), Postives = 369/581 (63.51%), Query Frame = 3 Query: 186 LPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNL--------ESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYR-AMKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMN 1892 LPI + K+ +++ V +NQI+I+ G TGSGKTTQI QYL EAG + IG TQPRR+AA+++A RV++E CLG EVGY +RF +S T IKYMTDG+LL +CL DP L +Y ++M+DEAHERT+ TDVL GL+K +R D+K+++TSAT+ KFS YF AP+ + G+ Y V+I+Y EP + + ++Q IH GDIL+FLTGQE+I+ C+ L + L +LP+Y AL + Q IF PA PG RKV+++TNIAETS+TIDGI +V+D G+VKQ +++S++GID L ISQ QA QR GRAGRT G CYRLYTE YR M PEI R NL T L + +GI D +SF F+D+P ETL + +L L +D+ +T LG+ + +FP+EP + K L S C E++TI++M+S +NVF RPK +D K KF +EGD L Y +W N+ S WCY+NF+ +++ + +R Q++G++ R + + V ++K++ F++N + + Y ++QQV+Y+HPSS L N Sbjct: 565 LPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRRVAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLDASLITVMQ-IHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKSTV-RVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFN 1143
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Human
Match: DHX16 (DEAH-box helicase 16 [Source:HGNC Symbol;Acc:HGNC:2739]) HSP 1 Score: 494.967 bits (1273), Expect = 2.033e-161 Identity = 263/628 (41.88%), Postives = 384/628 (61.15%), Query Frame = 3 Query: 147 TQQLQGIKVSDKELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAG-INNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNLE--------SIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYRAMKQETT-PEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERN-VFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTE 1988 QQ + I+ + LP+ +++ ++ + N+Q++II G TGSGKTTQIPQYLFE G N I TQPRR+AA+++A+RVA+EM LG EVGY +RF +S T ++YMTDG+LL + L +P L Y V+M+DEAHERT+ TD+L GLIK +A R +LKVL+ SAT+ +FS +F GAPV G+ + V I Y P + + +++Q IH GDIL+FLTGQE+IE C+ L+ I+ L VLP+Y L D Q IF+P PG RKV+V+TNIAETS+TI+GI +V+D G+ KQ ++ R+G++SLT S+ A QR GRAGR G C+RLYT Y+ +ETT PEI R +L L + +GI D M F F+D P +ETL L +L L ++ ++T G+ + + PV+P + K + AS KY C E++T+ AM+S N +F RPK V +D ++ FF GD + LN Y W+E+ S QWCY+NFV F++M + VR QL GL++R + + ++K++ ++ + R ++ Y QQ +++HP+S L +LY+E+V T K +MR ++ + S L E Sbjct: 386 AQQKESIQAVRRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKGMKIACTQPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDTARFSTFFDGAPVFRIPGRRFPVDIFYTKAPEADYLEACVVSVLQ-IHVTQPPGDILVFLTGQEEIEAACEMLQDRCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSLTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETLLLALEQLYALGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCYENFVQFRSMRRARDVREQLEGLLERVEVGLSSCQGDYI-RVRKAITAGYFYHTA-RLTRSGYRTVKQQQTVFIHPNSSLFEQQPRWLLYHELVLTTKEFMRQVLEIESSWLLE 1010
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Human
Match: DHX16 (DEAH-box helicase 16 [Source:HGNC Symbol;Acc:HGNC:2739]) HSP 1 Score: 491.886 bits (1265), Expect = 2.621e-160 Identity = 262/628 (41.72%), Postives = 383/628 (60.99%), Query Frame = 3 Query: 147 TQQLQGIKVSDKELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAG-INNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNLE--------SIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYRAMKQETT-PEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERN-VFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTE 1988 QQ + I+ + LP+ +++ ++ + N+Q++II G TGSGKTTQIPQYLFE G N I TQPRR+AA+++A+RVA+EM LG EVGY +RF +S T ++YMTDG+LL + L +P L Y V+M+DEAHERT+ TD+L GLIK +A R +LKVL+ SAT+ +FS +F APV G+ + V I Y P + + +++Q IH GDIL+FLTGQE+IE C+ L+ I+ L VLP+Y L D Q IF+P PG RKV+V+TNIAETS+TI+GI +V+D G+ KQ ++ R+G++SLT S+ A QR GRAGR G C+RLYT Y+ +ETT PEI R +L L + +GI D M F F+D P +ETL L +L L ++ ++T G+ + + PV+P + K + AS KY C E++T+ AM+S N +F RPK V +D ++ FF GD + LN Y W+E+ S QWCY+NFV F++M + VR QL GL++R + + ++K++ ++ + R ++ Y QQ +++HP+S L +LY+E+V T K +MR ++ + S L E Sbjct: 386 AQQKESIQAVRRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKGMKIACTQPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDTARFSTFFDDAPVFRIPGRRFPVDIFYTKAPEADYLEACVVSVLQ-IHVTQPPGDILVFLTGQEEIEAACEMLQDRCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSLTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETLLLALEQLYALGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCYENFVQFRSMRRARDVREQLEGLLERVEVGLSSCQGDYI-RVRKAITAGYFYHTA-RLTRSGYRTVKQQQTVFIHPNSSLFEQQPRWLLYHELVLTTKEFMRQVLEIESSWLLE 1010
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Celegans
Match: mog-5 (Probable pre-mRNA-splicing factor ATP-dependent RNA helicase mog-5 [Source:UniProtKB/Swiss-Prot;Acc:Q09530]) HSP 1 Score: 499.975 bits (1286), Expect = 3.263e-162 Identity = 267/642 (41.59%), Postives = 389/642 (60.59%), Query Frame = 3 Query: 186 LPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNL--------ESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYR-AMKQETTPEIYRRNLYGTYLKIAGIGIDPM-SFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEFPKESKKIGYNSSISL*TKNLCDFDLLFD 2075 LPI K +++ + +NQI+++ G TGSGKTTQ+ QY EAG+ IG TQPRR+AA+++A RVA+E LG +VGY +RF +S T IKYMTDG+LL +CL DP L Y ++M+DEAHERT+ TDVL GL+K A +R +LK++ITSAT+ KFS YF AP+ + G+ + V+I+Y EP + L V +IH GD+L+FLTGQE+I+ C+ L + L +LP+YGAL + Q IF PA GKRKV+++TNIAETS+TIDGI +V+D G+VKQ +++ +SG+DSL ISQ A QR GRAGRT G CYRLYTE +R M PEI R NL T L++ +GI+ + F F+D+P +++ L+ L L +D +T+LG+ + +FP+EP + K L S C EV+TI+AM++ +N+F RPK+ +D K KF EGD L Y +W + S+ WC++NF+ ++M++ +R QL+G++ R + V ++K++ F++N R + Y + Q +Y+HPSS ++Y+E+V T K YMR + + L EF KIG ++ +S +N D LFD Sbjct: 540 LPIFALKKNLMEAMIDNQILVVVGETGSGKTTQMTQYAIEAGLGRRGKIGCTQPRRVAAMSVAKRVAEEYGCKLGTDVGYTIRFEDCTSQDTIIKYMTDGMLLRECLIDPDLSGYSLIMLDEAHERTIHTDVLFGLLKAAARKRPELKLIITSATLDSVKFSEYFLEAPIFTIPGRTFPVEILYTREPESDY-LEAAHITVMQIHLTEPPGDVLVFLTGQEEIDTSCEVLYERMKSMGPDVPELIILPVYGALPSEMQTRIFDPAPAGKRKVVIATNIAETSLTIDGIFYVVDPGFVKQKIYNPKSGMDSLVVTPISQAAAKQRSGRAGRTGPGKCYRLYTERAFRDEMLPTPVPEIQRTNLASTLLQLKAMGINNLIDFDFMDAPPLDSMITALNTLHTLSALDGDGLLTKLGRRMAEFPLEPSLSKLLIMSVDLGCSEEVLTIVAMLNVQNIFYRPKEKQDHADQKKAKFHQPEGDHLTLLAVYNSWKNHHFSQPWCFENFIQVRSMKRAQDIRKQLLGIMDRHKLLMVSCGRD-VSRVQKAICSGFFRNAAKRDPQEGYRTLTDGQNVYIHPSSACFQQQPEWVVYHELVMTTKEYMREVTAIDPKWLVEFAPSFFKIGDSTKLSTFKRN-QKIDPLFD 1178
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Celegans
Match: mog-4 (Probable pre-mRNA-splicing factor ATP-dependent RNA helicase mog-4 [Source:UniProtKB/Swiss-Prot;Acc:O45244]) HSP 1 Score: 484.567 bits (1246), Expect = 2.991e-158 Identity = 260/622 (41.80%), Postives = 379/622 (60.93%), Query Frame = 3 Query: 165 IKVSDKELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGI-NNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNL--------ESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYR-AMKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMS-ERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTE 1988 I+ + K LP+ ++D I+ V+ +Q++II G TGSGKTTQ+PQYL+EAG K IG TQPRR+AA+++A+RVA E+ LG +VGY +RF +S T +KYMTDG+LL + L +P L Y V+MIDEAHERT+ TD+L GL+K +A R DLK+LI+SAT+ EKFS++F AP+ G+ + V I Y P + I I+Q GDIL+FLTGQE+IE + L I+ L LP+Y L D Q IF+P RKV+++TNIAETS+TIDGI +VID G+ KQN FD+RSG++ L V IS+ A QR GRAGRT G C+RLYT Y+ ++++ PEI R NL L + +GI D + F F+D P ETL L +L L ++ ++T+LG+ + +FP +P + K + AS KY C E++TI AM+S VF RPK + +D +++ F+S GD +N Y W E+ S++WC +N+V +TM++ VR QL+GL++R + S + I+K++ ++ N+ + G Y ++ + HP+SCL ++Y+E+V T K +MR + + L E Sbjct: 357 IEETRKSLPVYAFRDAFIEAVKEHQVLIIEGETGSGKTTQLPQYLYEAGFCEGGKRIGCTQPRRVAAMSVAARVADEVGCKLGTQVGYSIRFEDCTSEKTVLKYMTDGMLLREFLNEPDLASYSVMMIDEAHERTLHTDILFGLVKDIARFRKDLKLLISSATLDAEKFSSFFDDAPIFRIPGRRFPVDIYYTQAPEADYVDAAIVTIMQIHLTQPLPGDILVFLTGQEEIETVQEALMERSKALGSKIKELIPLPVYANLPSDLQAKIFEPTPKDARKVVLATNIAETSVTIDGINYVIDPGFSKQNSFDARSGVEHLHVVTISKAAANQRAGRAGRTGPGKCFRLYTAWAYKHELEEQPIPEIQRTNLGNVVLMLKSLGIHDLVHFDFLDPPPQETLVIALEQLYALGALNHRGELTKLGRRMAEFPCDPCMSKMIIASEKYECSEEIVTIAAMLSCNAAVFYRPKAQVIHADSARKGFWSPAGDHITLMNVYNKWQESSFSQRWCVENYVQHRTMKRARDVRDQLVGLLERVEIETKSSTDTI--KIRKAITAGYFYNVSKLDNTGHYKTVKHKHTTHPHPNSCLFEETPRWVVYFELVFTSKEFMREMSEIESGWLLE 976
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Celegans
Match: ddx-15 (Pre-mRNA-splicing factor ATP-dependent RNA helicase ddx-15 [Source:UniProtKB/Swiss-Prot;Acc:Q20875]) HSP 1 Score: 462.611 bits (1189), Expect = 1.944e-153 Identity = 252/623 (40.45%), Postives = 380/623 (61.00%), Query Frame = 3 Query: 183 ELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFE--------AGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIYEPMWSWS-LYFITNIVQKIHNGIE-KGDILLFLTGQEDIEECCQNLE-SIQ-------SLTVLPLYGALDFDAQQDIFKPAEPGK------RKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYRA-MKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGL-----VKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGI 1958 +LP+ +YK+ ++ +RNNQ + + G TGSGKTTQIPQ+ E + + TQPRR+AA+++A+RVA+EM LG EVGY +RF S T +KY TDG+LL + + P L +Y VL++DEAHERT+ TD+L+GLIK + R D+KV+I SAT+ KF YF P++S G+ + V+I + P L V +IH E +GDILLFLTGQE+IEE C+ ++ IQ +L+ +PLY L AQQ IF+PA P + RK ++STNIAETS+TIDG+ FVID G+ KQ +++ R ++SL IS+ A+QR GRAGRT G C+RLYTE Y + M+ +T PEI R NL L++ +G D + F F+D P ETL + L L L I++ ++TELG + +FP++P++ K L S++ C E+++I AM+S ++RP + ++D +K +F +GD LN Y ++ +N++ QWCYDNF+N++TM+ D VRTQL + ++R +++ D L +I+K+L+ F+ + + G Y+ + Q++ +HPS+ L + LY E V T K ++R + Sbjct: 75 QLPVWEYKEKFMELLRNNQCITLVGETGSGKTTQIPQWAVEFMKQQQQGQPPGQARLVACTQPRRVAAMSVATRVAEEMDVVLGQEVGYSIRFEDCISERTVLKYCTDGMLLREAMNSPLLDKYKVLILDEAHERTLATDILMGLIKEIVRNRADIKVVIMSATLDAGKFQRYFEDCPLLSVPGRTFPVEIFFTPNAEKDYLEAAIRTVIQIHMVEEVEGDILLFLTGQEEIEEACKRIDREIQALGADAGALSCIPLYSTLPPAAQQRIFEPAPPNRPNGAISRKCVISTNIAETSLTIDGVVFVIDPGFSKQKVYNPRIRVESLLVCPISKASAMQRAGRAGRTKPGKCFRLYTETAYGSEMQDQTYPEILRSNLGSVVLQLKKLGTEDLVHFDFMDPPAPETLMRALELLNYLQAINDDGELTELGSLMAEFPLDPQLAKMLITSTELNCSNEILSITAMLSVPQCWVRPNEMRTEADEAKARFAHIDGDHLTLLNVYHSFKQNQEDPQWCYDNFINYRTMKTADTVRTQLSRVMDKYNLRRVSTDFKSRDYYL--NIRKALVAGFFMQVAHLERSGHYVTVKDNQLVNLHPSTVL-DHKPEWALYNEFVLTTKNFIRTV 694
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Celegans
Match: ddx-15 (Pre-mRNA-splicing factor ATP-dependent RNA helicase ddx-15 [Source:UniProtKB/Swiss-Prot;Acc:Q20875]) HSP 1 Score: 461.84 bits (1187), Expect = 9.602e-153 Identity = 252/623 (40.45%), Postives = 380/623 (61.00%), Query Frame = 3 Query: 183 ELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFE--------AGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIYEPMWSWS-LYFITNIVQKIHNGIE-KGDILLFLTGQEDIEECCQNLE-SIQ-------SLTVLPLYGALDFDAQQDIFKPAEPGK------RKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYRA-MKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGL-----VKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGI 1958 +LP+ +YK+ ++ +RNNQ + + G TGSGKTTQIPQ+ E + + TQPRR+AA+++A+RVA+EM LG EVGY +RF S T +KY TDG+LL + + P L +Y VL++DEAHERT+ TD+L+GLIK + R D+KV+I SAT+ KF YF P++S G+ + V+I + P L V +IH E +GDILLFLTGQE+IEE C+ ++ IQ +L+ +PLY L AQQ IF+PA P + RK ++STNIAETS+TIDG+ FVID G+ KQ +++ R ++SL IS+ A+QR GRAGRT G C+RLYTE Y + M+ +T PEI R NL L++ +G D + F F+D P ETL + L L L I++ ++TELG + +FP++P++ K L S++ C E+++I AM+S ++RP + ++D +K +F +GD LN Y ++ +N++ QWCYDNF+N++TM+ D VRTQL + ++R +++ D L +I+K+L+ F+ + + G Y+ + Q++ +HPS+ L + LY E V T K ++R + Sbjct: 75 QLPVWEYKEKFMELLRNNQCITLVGETGSGKTTQIPQWAVEFMKQQQQGQPPGQARLVACTQPRRVAAMSVATRVAEEMDVVLGQEVGYSIRFEDCISERTVLKYCTDGMLLREAMNSPLLDKYKVLILDEAHERTLATDILMGLIKEIVRNRADIKVVIMSATLDAGKFQRYFEDCPLLSVPGRTFPVEIFFTPNAEKDYLEAAIRTVIQIHMVEEVEGDILLFLTGQEEIEEACKRIDREIQALGADAGALSCIPLYSTLPPAAQQRIFEPAPPNRPNGAISRKCVISTNIAETSLTIDGVVFVIDPGFSKQKVYNPRIRVESLLVCPISKASAMQRAGRAGRTKPGKCFRLYTETAYGSEMQDQTYPEILRSNLGSVVLQLKKLGTEDLVHFDFMDPPAPETLMRALELLNYLQAINDDGELTELGSLMAEFPLDPQLAKMLITSTELNCSNEILSITAMLSVPQCWVRPNEMRTEADEAKARFAHIDGDHLTLLNVYHSFKQNQEDPQWCYDNFINYRTMKTADTVRTQLSRVMDKYNLRRVSTDFKSRDYYL--NIRKALVAGFFMQVAHLERSGHYVTVKDNQLVNLHPSTVL-DHKPEWALYNEFVLTTKNFIRTV 694
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Celegans
Match: mog-1 (Probable pre-mRNA-splicing factor ATP-dependent RNA helicase mog-1 [Source:UniProtKB/Swiss-Prot;Acc:P34498]) HSP 1 Score: 453.366 bits (1165), Expect = 5.068e-145 Identity = 243/631 (38.51%), Postives = 373/631 (59.11%), Query Frame = 3 Query: 159 QGIKVSDKELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSG-APVISFDGKMYDVQIIYE--PMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQ-------NLESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYR-AMKQETTPEIYRRNLYGTYLKIAGIGIDP-MSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLV------DSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCL--MNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEF 1991 + IK + LP+ + ++ +R N +VII G TGSGKTTQ+ QYL E G + IG TQPRR+AA+++A RVA EM LG +VGY +RF +S T IKYMTDGILL +CL D L +Y +++DEAHER+++TDVL GL++ + ++R DLK+++TSAT+ +KF+++F G P + G+ + V++ + P+ + + V IH G GDIL+F+ GQEDIE C+ L+ L VLP+Y L D Q IF+ A G RK IV+TNIAETS+T+DGI FVID G+ K +++ R G+D+L+ +SQ A QR GRAGRT G CYRLYTE ++ + + T PEI R NL L + +G+D + F F+D+P + + + +L L +D ++T +G+ + +FP++P + K L S++ C EV+TI++M+S +F RPK ++D K+KF E D +LN Y W ++ S +WC DN+++ K ++++ VR QL ++ QD L L+ D ++K + +++ N K G Y+N ++HP+S L M ++Y+E++ T K YM+ + + L E Sbjct: 432 KSIKQQREYLPVFACRQKMMNVIRENNVVIIVGETGSGKTTQLAQYLLEDGFGDSGLIGCTQPRRVAAMSVARRVADEMGVDLGQDVGYAIRFEDCTSEKTIIKYMTDGILLRECLGDGSLDQYSAIIMDEAHERSLNTDVLFGLLREVIAKRADLKLIVTSATMDADKFADFFGGNCPTFTIPGRTFPVELFHARTPVEDYVDAAVKQAVT-IHLGGMDGDILIFMPGQEDIECTCEMIKEKLGELDEAPPLAVLPIYSQLPSDLQAKIFQRAPGGMRKAIVATNIAETSLTVDGILFVIDPGFCKMKVYNPRIGMDALSIFPVSQASANQRTGRAGRTGPGQCYRLYTERQFKDELLKSTVPEIQRTNLANVVLLLKSLGVDDLLKFHFMDAPPQDNMLNSMYQLWTLGALDNTGQLTPMGRKMVEFPLDPTLSKMLIMSAEMGCSDEVLTIVSMLSVPAIFFRPKGREEEADAKKEKFQVPESDHLTFLNVYIQWRTHKYSAKWCADNYLHVKALKKVREVRAQLKEIM-------QDLKLPLISNGSEWDIVRKCICSAYFHNAARLKGIGEYVNVRTGIPCFLHPTSALFGMGFMPDYVVYHELIMTAKEYMQCVTAVDAIWLAEL 1054
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Fly
Match: pea (gene:FBgn0086895 transcript:FBtr0087518) HSP 1 Score: 517.694 bits (1332), Expect = 1.915e-168 Identity = 272/616 (44.16%), Postives = 384/616 (62.34%), Query Frame = 3 Query: 180 KELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNL--------ESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYR-AMKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEF 1991 + LPI + +D +IK V +NQI+I+ G TGSGKTTQI QYL E G IG TQPRR+AA+++A RVA+E LG EVGY +RF +S T IKYMTDG+LL +CL + +L Y V+M+DEAHERT+ TDVL GL+K +R +LK+++TSAT+ KFS YF AP+ + G+ + V+++Y EP + + ++Q IH GDILLFLTGQE+I+ C+ L + L +LP+Y AL + Q IF PA G RKV+++TNIAETS+TIDGI +V+D G+VKQ +++S++G+DSL ISQ A QR GRAGRT G YRLYTE YR M PEI R NL T L++ +GI D + F F+D+P E+L L +L L +D+ +T LG+ + +FP+EP + K L S C E++TI++M+S +NVF RPK +D K KF +EGD L Y +W N+ S WCY+NFV +T+++ VR QL+G++ R + + N V I+K++ F++N + + Y ++ QV+Y+HPSS L N ++Y+E+VQT K YMR + T+ L EF Sbjct: 584 QSLPIYKLRDDLIKAVTDNQILIVIGETGSGKTTQITQYLGECGFTARGKIGCTQPRRVAAMSVAKRVAEEYGCRLGQEVGYTIRFEDCTSPETIIKYMTDGMLLRECLMEAELKSYSVIMLDEAHERTIHTDVLFGLLKTAVQKRPELKLIVTSATLDAVKFSQYFFKAPIFTIPGRTFPVEVLYTKEPETDYLDASLITVMQ-IHLREPPGDILLFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPAGSRKVVIATNIAETSLTIDGIFYVVDPGFVKQKVYNSKTGMDSLVVTPISQAAAKQRAGRAGRTGPGKTYRLYTERAYRDEMLPTPVPEIQRTNLATTVLQLKTMGINDLLHFDFMDAPPVESLVMALEQLHSLSALDDEGLLTRLGRRMAEFPLEPNLSKMLIMSVALQCSDEILTIVSMLSVQNVFYRPKDKQALADQKKAKFNQAEGDHLTLLAVYNSWKNNKFSNAWCYENFVQIRTLKRSQDVRKQLLGIMDRHKLDVVSAGKNSV-RIQKAICSGFFRNAAKKDPQEGYRTLVDSQVVYIHPSSALFNRQPEWVIYHELVQTTKEYMREVTTIDPKWLVEF 1197
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Fly
Match: l(2)37Cb (gene:FBgn0086444 transcript:FBtr0081163) HSP 1 Score: 494.967 bits (1273), Expect = 1.724e-163 Identity = 264/623 (42.38%), Postives = 382/623 (61.32%), Query Frame = 3 Query: 180 KELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKT-IGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNLES--------IQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYR-AMKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMS-ERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVD------SIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTE 1988 + LP+ +K+ +I V+ +Q++II G TGSGKTTQ+PQYL EAG DK IG TQPRR+AA+++A+RVA+EM LG EVGY +RF +S+ T +KYMTDG L + L +P L Y V++IDEAHERT+ TD+L GL+K +A R +LK+LI+SAT+ EKFS +F AP+ G+ Y V I Y P + +++Q IH GDIL+FLTGQ++IE C + L I+ L V+P+Y L D Q IF+P P RKVI++TNIAETS+TID I +VID G+ KQN F+SR+G++SL V IS+ A QR GRAGRT G C+RLYT Y+ ++ T PEI R NL L + +GI D + F F+D P HETL L +L L ++ ++T+LG+ + +FPV+P +GK L AS KY C E++TI AM+S +F RPK + +D +++ F GD L Y W+E S QWCY+NF+ +++M++ VR QL+GL++R ++++V +++K+ ++ ++ G Y + Q + +HP+S L +LY+E+V T K YMR ++ + L E Sbjct: 250 RSLPVYPFKEDLIAAVKEHQVLIIEGETGSGKTTQVPQYLVEAGFTKDKKMIGCTQPRRVAAMSVAARVAEEMGVKLGNEVGYSIRFEDCTSDRTILKYMTDGTLHREFLSEPDLASYSVMIIDEAHERTLHTDILFGLVKDIARFRPELKLLISSATLDAEKFSAFFDDAPIFRIPGRRYPVDIFYTKAPEADYIDACCVSVLQ-IHATQPLGDILVFLTGQDEIETCQEVLHDRVKRLGSKIRELIVIPVYANLPSDMQAKIFEPTPPNARKVILATNIAETSLTIDNIIYVIDPGFAKQNNFNSRTGMESLMVVPISKASANQRAGRAGRTAPGKCFRLYTAWAYKHELEDNTVPEIQRINLGNAVLMLKALGINDLIHFDFLDPPPHETLVLALEQLYALGALNHHGELTKLGRRMAEFPVDPMMGKMLLASEKYKCSEEMVTIAAMLSVNSAIFYRPKDKIIHADTARKNFNHMHGDHLSLLQVYNQWAETDYSTQWCYENFIQYRSMKRARDVREQLVGLMQR-------VEIDMVSCLPETVNVRKAATAGYFYHVARLSKGGHYKTIKHNQTVMIHPNSSLFEELPRWVLYHELVFTSKEYMRQVIEIESKWLLE 864
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Fly
Match: Dhx15 (gene:FBgn0033160 transcript:FBtr0336909) HSP 1 Score: 457.218 bits (1175), Expect = 7.029e-151 Identity = 245/627 (39.07%), Postives = 383/627 (61.08%), Query Frame = 3 Query: 147 TQQLQGIKVSDKELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINND-KTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIE-KGDILLFLTGQEDIEECCQNLE--------SIQSLTVLPLYGALDFDAQQDIFKPAEPGK------RKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYR-AMKQETTPEIYRRNLYGTYLKIAGIGIDPM-SFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVD---SIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGI 1958 +Q+ Q + LP+ +Y+ ++ + +Q +++ G TGSGKTTQIPQ+ + ++ K + TQPRR+AA+++A RV++EM LG EVGY +RF S+ T +KYMTDG+LL + + DP L +Y V+++DEAHERT+ TD+L+G++K + +R+DLK+++ SAT+ KF YF AP++ G+ + V+I Y EP + I ++Q IH E +GDIL+FLTGQE+IEE C+ ++ I L +PLY L + QQ IF+PA P RKV+VSTNIAETS+TIDG+ FVID G+ KQ +++ R ++SL IS+ A QR GRAGRT G C+RLYTE+ ++ M+ T PEI R NL L++ +GID + F F+D P ETL + L L L +D+ +T+LG + +FP++P++ K L AS ++ C E+++I AM+S F+RP ++ +D +K +F +GD LN Y A+ ++ + WCY+NF+NF++++ D VR QL ++ R ++ D +I+K+L+ F+ + + G Y+ + Q + +HPS+CL + ++Y E V T K Y+R + Sbjct: 59 SQRYQNLYKKRIALPVFEYQADFMRLLSLHQCIVLVGETGSGKTTQIPQWCVDFAVSKGRKGVSCTQPRRVAAMSVAQRVSEEMDVKLGEEVGYSIRFEDCSTAKTLLKYMTDGMLLREAMSDPMLDQYQVILLDEAHERTLATDILMGVLKEVIRQRSDLKLVVMSATLDAGKFQQYFDNAPLMKVPGRTHPVEIFYTPEPERDYLEAAIRTVIQ-IHMCEEIEGDILMFLTGQEEIEEACKRIKREIDNLGSEIGELKCIPLYSTLPPNLQQRIFEPAPPPNANGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVSPISKASAQQRSGRAGRTRPGKCFRLYTEKAFKNEMQDNTYPEILRSNLGTVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLAALDDDGNLTDLGAVMSEFPLDPQLAKMLIASCQHNCSNEILSITAMLSVPQCFVRPNEAKKAADEAKMRFAHIDGDHLTLLNVYHAFKQSSEDPNWCYENFINFRSLKSADNVRQQLARIMDRFNLRRTSTEFTSKDYYVNIRKALVQGFFMQVAHLERTGYYLTIKDNQNVQLHPSTCL-DHKPDWVIYNEFVLTTKNYIRTV 683
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Fly
Match: Dhx15 (gene:FBgn0033160 transcript:FBtr0088966) HSP 1 Score: 457.218 bits (1175), Expect = 7.029e-151 Identity = 245/627 (39.07%), Postives = 383/627 (61.08%), Query Frame = 3 Query: 147 TQQLQGIKVSDKELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINND-KTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIE-KGDILLFLTGQEDIEECCQNLE--------SIQSLTVLPLYGALDFDAQQDIFKPAEPGK------RKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYR-AMKQETTPEIYRRNLYGTYLKIAGIGIDPM-SFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVD---SIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGI 1958 +Q+ Q + LP+ +Y+ ++ + +Q +++ G TGSGKTTQIPQ+ + ++ K + TQPRR+AA+++A RV++EM LG EVGY +RF S+ T +KYMTDG+LL + + DP L +Y V+++DEAHERT+ TD+L+G++K + +R+DLK+++ SAT+ KF YF AP++ G+ + V+I Y EP + I ++Q IH E +GDIL+FLTGQE+IEE C+ ++ I L +PLY L + QQ IF+PA P RKV+VSTNIAETS+TIDG+ FVID G+ KQ +++ R ++SL IS+ A QR GRAGRT G C+RLYTE+ ++ M+ T PEI R NL L++ +GID + F F+D P ETL + L L L +D+ +T+LG + +FP++P++ K L AS ++ C E+++I AM+S F+RP ++ +D +K +F +GD LN Y A+ ++ + WCY+NF+NF++++ D VR QL ++ R ++ D +I+K+L+ F+ + + G Y+ + Q + +HPS+CL + ++Y E V T K Y+R + Sbjct: 59 SQRYQNLYKKRIALPVFEYQADFMRLLSLHQCIVLVGETGSGKTTQIPQWCVDFAVSKGRKGVSCTQPRRVAAMSVAQRVSEEMDVKLGEEVGYSIRFEDCSTAKTLLKYMTDGMLLREAMSDPMLDQYQVILLDEAHERTLATDILMGVLKEVIRQRSDLKLVVMSATLDAGKFQQYFDNAPLMKVPGRTHPVEIFYTPEPERDYLEAAIRTVIQ-IHMCEEIEGDILMFLTGQEEIEEACKRIKREIDNLGSEIGELKCIPLYSTLPPNLQQRIFEPAPPPNANGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVSPISKASAQQRSGRAGRTRPGKCFRLYTEKAFKNEMQDNTYPEILRSNLGTVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLAALDDDGNLTDLGAVMSEFPLDPQLAKMLIASCQHNCSNEILSITAMLSVPQCFVRPNEAKKAADEAKMRFAHIDGDHLTLLNVYHAFKQSSEDPNWCYENFINFRSLKSADNVRQQLARIMDRFNLRRTSTEFTSKDYYVNIRKALVQGFFMQVAHLERTGYYLTIKDNQNVQLHPSTCL-DHKPDWVIYNEFVLTTKNYIRTV 683
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Fly
Match: l(1)G0007 (gene:FBgn0026713 transcript:FBtr0073900) HSP 1 Score: 431.795 bits (1109), Expect = 5.309e-136 Identity = 230/615 (37.40%), Postives = 362/615 (58.86%), Query Frame = 3 Query: 186 LPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIYEPMWSWSLYFITNIVQ--KIHNGIEKGDILLFLTGQEDIEECCQNLE-------SIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYR-AMKQETTPEIYRRNLYGTYLKIAGIG-IDPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCL--MNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEF 1991 LP+ + ++ +R N ++II G TGSGKTTQ+ QYL E G + IG TQPRR+AA+++A RV+ EM + LG +VGY +RF +S T IKYMTDGILL + L DP+L Y +++DEAHER++ TDVL GL++ + +RR DLK+++TSAT+ KF+ +F P + G+ + V +++ + Y + + Q ++H +GD+L+F+ GQEDIE C+ LE + +L++LP+Y L D Q IF+ + G RK +V+TNIAETS+T+DGI +VID GY K +++ R G+D+L ISQ A QR GRAGRT G YRLYT+ Y+ + T PEI R NL T L + +G +D + F F+D P + + L +L L +D +T LG+ + +FP++P + L + + C EV+ I++M+S ++F RPK ++D ++KF E D YLN Y+ W +N S WC ++F++ K M ++ VR QL ++ ++ + ++ D ++K + +++ K G Y+N ++HP+S L + T ++Y+E++ T K YM+ + L E Sbjct: 534 LPVFASRQELLNVIRENSVIIIVGETGSGKTTQLTQYLHEDGYSKRGMIGCTQPRRVAAMSVAKRVSDEMDTQLGEDVGYAIRFEDCTSERTVIKYMTDGILLRESLRDPELDSYSAIIMDEAHERSLSTDVLFGLLREIVARRHDLKLIVTSATMDSSKFATFFGNVPTFTIPGRTFPVDVMFSKN-TCEDYVESAVKQALQVHLTPNEGDMLIFMPGQEDIEVTCEVLEERLAEIDNAPALSILPIYSQLPSDLQAKIFQKSSDGLRKCVVATNIAETSLTVDGIIYVIDSGYCKLKVYNPRIGMDALQIYPISQANANQRSGRAGRTGPGQAYRLYTQRQYKDELLALTVPEIQRTNLANTVLLLKSLGVVDLLQFHFMDPPPQDNILNSLYQLWILGALDHTGALTTLGRQMAEFPLDPPQCQMLIVACRMGCSAEVLIIVSMLSVPSIFYRPKGREDEADGVREKFQRPESDHLTYLNVYQQWRQNNYSSTWCNEHFIHIKAMRKVREVRQQLKDIMTQQNLSVISCGIDW-DIVRKCICSAYFYQAARLKGIGEYVNLRTGMPCHLHPTSALYGLGTTPDYVVYHELIMTAKEYMQCATAVDGYWLAEL 1146
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Zebrafish
Match: AL833789.3 (DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Source:NCBI gene;Acc:606595]) HSP 1 Score: 530.02 bits (1364), Expect = 5.617e-174 Identity = 272/614 (44.30%), Postives = 385/614 (62.70%), Query Frame = 3 Query: 186 LPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNL--------ESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYR-AMKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEF 1991 LPI + K+ +I+ V +NQI+I+ G TGSGKTTQI QYL EAG IG TQPRR+AA+++A RV++E CLG EVGY +RF +S T IKYMTDG+LL +CL DP L +Y ++M+DEAHERT+ TDVL GL+K +RTD+K+++TSAT+ KFS YF AP+ + G+ Y V+++Y EP + + ++Q IH GDIL+FLTGQE+I+ C+ L + L +LP+Y AL + Q IF PA PG RKV+++TNIAETS+TIDGI +V+D G+VKQ +++S++GID L ISQ QA QR GRAGRT G CYRLYTE YR M PEI R NL T L + +GI D +SF F+D+P ETL + +L L +D+ +T LG+ + +FP+EP + K L S C E++TI++M+S +NVF RPK +D K KF EGD L Y +W N+ S WCY+NF+ +++ + +R Q++G++ R + V ++K++ F++N + + Y ++QQV+Y+HPSS L N ++Y+E+V T K YMR + T+ L EF Sbjct: 502 LPIYKLKEQLIQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTTRGKIGCTQPRRVAAMSVAKRVSEEYGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLGQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRTDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEVLYTKEPETDYLDASLITVMQ-IHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQPEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKATV-RVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTIDPRWLVEF 1113
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Zebrafish
Match: dhx8 (DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Source:ZFIN;Acc:ZDB-GENE-050809-39]) HSP 1 Score: 530.791 bits (1366), Expect = 1.243e-173 Identity = 272/614 (44.30%), Postives = 385/614 (62.70%), Query Frame = 3 Query: 186 LPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNL--------ESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYR-AMKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEF 1991 LPI + K+ +I+ V +NQI+I+ G TGSGKTTQI QYL EAG IG TQPRR+AA+++A RV++E CLG EVGY +RF +S T IKYMTDG+LL +CL DP L +Y ++M+DEAHERT+ TDVL GL+K +RTD+K+++TSAT+ KFS YF AP+ + G+ Y V+++Y EP + + ++Q IH GDIL+FLTGQE+I+ C+ L + L +LP+Y AL + Q IF PA PG RKV+++TNIAETS+TIDGI +V+D G+VKQ +++S++GID L ISQ QA QR GRAGRT G CYRLYTE YR M PEI R NL T L + +GI D +SF F+D+P ETL + +L L +D+ +T LG+ + +FP+EP + K L S C E++TI++M+S +NVF RPK +D K KF EGD L Y +W N+ S WCY+NF+ +++ + +R Q++G++ R + V ++K++ F++N + + Y ++QQV+Y+HPSS L N ++Y+E+V T K YMR + T+ L EF Sbjct: 555 LPIYKLKEQLIQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTTRGKIGCTQPRRVAAMSVAKRVSEEYGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLGQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRTDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEVLYTKEPETDYLDASLITVMQ-IHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQPEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKATV-RVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTIDPRWLVEF 1166
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Zebrafish
Match: dhx8 (DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Source:ZFIN;Acc:ZDB-GENE-050809-39]) HSP 1 Score: 520.39 bits (1339), Expect = 2.431e-169 Identity = 272/641 (42.43%), Postives = 384/641 (59.91%), Query Frame = 3 Query: 186 LPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY----------------------EPMWSWSLYFITNIVQKIHNGIE-------KGDILLFLTGQEDIEECCQNL--------ESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYR-AMKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEF 1991 LPI + K+ +I+ V +NQI+I+ G TGSGKTTQI QYL EAG IG TQPRR+AA+++A RV++E CLG EVGY +RF +S T IKYMTDG+LL +CL DP L +Y ++M+DEAHERT+ TDVL GL+K +RTD+K+++TSAT+ KFS YF AP+ + G+ Y V+++Y EP S + N + K + GDIL+FLTGQE+I+ C+ L + L +LP+Y AL + Q IF PA PG RKV+++TNIAETS+TIDGI +V+D G+VKQ +++S++GID L ISQ QA QR GRAGRT G CYRLYTE YR M PEI R NL T L + +GI D +SF F+D+P ETL + +L L +D+ +T LG+ + +FP+EP + K L S C E++TI++M+S +NVF RPK +D K KF EGD L Y +W N+ S WCY+NF+ +++ + +R Q++G++ R + V ++K++ F++N + + Y ++QQV+Y+HPSS L N ++Y+E+V T K YMR + T+ L EF Sbjct: 555 LPIYKLKEQLIQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTTRGKIGCTQPRRVAAMSVAKRVSEEYGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLGQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRTDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEVLYTKEPETDYLDASLITVMQIHLTEPPGKLSNTILQNKIIKFEKQFQLIKIINCAGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQPEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKATV-RVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTIDPRWLVEF 1194
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Zebrafish
Match: dhx16 (DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Source:ZFIN;Acc:ZDB-GENE-030131-8589]) HSP 1 Score: 495.352 bits (1274), Expect = 1.233e-161 Identity = 271/632 (42.88%), Postives = 388/632 (61.39%), Query Frame = 3 Query: 135 LSFLTQQLQGIKVSDKELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAG-INNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNLES--------IQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYRAMKQETT-PEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERN-VFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTE 1988 LS +Q Q I+ + LPI Y++ ++ + ++QI++I G TGSGKTTQIPQYL E G IG TQPRR+AA+++A+RVAQEM LG EVGY +RF +S T +KYMTDG+LL + L +P L Y V++IDEAHERT+ TD+L GLIK +A R DLKVL+ SAT+ E+FS++F APV G+ + V I Y P + + +++Q IH GD+L+FLTGQE+IE CC+ L+ I L VLP+Y L D Q IF P PG RKV+V+TNIAETS+TIDGI +VID G+ KQ +++++G++SL S+ A QR GRAGR G C+RLYT ++ +ETT PEI R NL L + +GI D + F F+D P HETL L +L L ++ ++T+LG+ + + PV+P + K + AS +Y C EV+TI AM+S N +F RPK V +D ++ F GD + LN Y W E+ S QWC++NF+ F++M++ VR QL GL+ R S+ + + I+K++ ++ + R SKG Y +QQ +Y+HP+S L ++Y+E+V T K +MR ++ + L E Sbjct: 395 LSQAEKQKQSIQEVRRSLPIFPYREDLLAAIGDHQILVIEGETGSGKTTQIPQYLLEEGYTKGGMKIGCTQPRRVAAMSVAARVAQEMSVKLGNEVGYSIRFEDCTSERTILKYMTDGMLLREFLTEPDLASYSVIIIDEAHERTLHTDILFGLIKDIARFRPDLKVLVASATLDTERFSSFFDDAPVFRIPGRRFPVDIYYTKAPEADYLEACVVSVLQ-IHVTQSPGDVLVFLTGQEEIEACCELLQERCRRLGSKISELLVLPIYANLPSDMQAKIFNPTPPGARKVVVATNIAETSLTIDGIIYVIDPGFCKQKSYNAKTGMESLIVTPCSRASANQRAGRAGRVAAGKCFRLYTAWAFKHEMEETTVPEIQRTNLGNVVLLLKSLGINDLIHFDFMDPPPHETLVLALEQLYALGALNHLGELTKLGRRMAELPVDPMLSKMILASEQYKCSEEVLTIAAMLSVNNSIFYRPKDKVVHADNARMNFVVPGGDHLVLLNVYTQWVESGYSTQWCFENFIQFRSMKRARDVRDQLEGLMDRIEVELCSSNGDSM-PIRKAVTAGYFYHTA-RLSKGGYKTVKHQQTVYVHPNSSLFEEQPRWMIYHELVFTTKEFMRQVIEIESGWLLE 1023
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Zebrafish
Match: dhx16 (DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Source:ZFIN;Acc:ZDB-GENE-030131-8589]) HSP 1 Score: 495.352 bits (1274), Expect = 1.233e-161 Identity = 271/632 (42.88%), Postives = 388/632 (61.39%), Query Frame = 3 Query: 135 LSFLTQQLQGIKVSDKELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAG-INNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNLES--------IQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYRAMKQETT-PEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERN-VFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTE 1988 LS +Q Q I+ + LPI Y++ ++ + ++QI++I G TGSGKTTQIPQYL E G IG TQPRR+AA+++A+RVAQEM LG EVGY +RF +S T +KYMTDG+LL + L +P L Y V++IDEAHERT+ TD+L GLIK +A R DLKVL+ SAT+ E+FS++F APV G+ + V I Y P + + +++Q IH GD+L+FLTGQE+IE CC+ L+ I L VLP+Y L D Q IF P PG RKV+V+TNIAETS+TIDGI +VID G+ KQ +++++G++SL S+ A QR GRAGR G C+RLYT ++ +ETT PEI R NL L + +GI D + F F+D P HETL L +L L ++ ++T+LG+ + + PV+P + K + AS +Y C EV+TI AM+S N +F RPK V +D ++ F GD + LN Y W E+ S QWC++NF+ F++M++ VR QL GL+ R S+ + + I+K++ ++ + R SKG Y +QQ +Y+HP+S L ++Y+E+V T K +MR ++ + L E Sbjct: 395 LSQAEKQKQSIQEVRRSLPIFPYREDLLAAIGDHQILVIEGETGSGKTTQIPQYLLEEGYTKGGMKIGCTQPRRVAAMSVAARVAQEMSVKLGNEVGYSIRFEDCTSERTILKYMTDGMLLREFLTEPDLASYSVIIIDEAHERTLHTDILFGLIKDIARFRPDLKVLVASATLDTERFSSFFDDAPVFRIPGRRFPVDIYYTKAPEADYLEACVVSVLQ-IHVTQSPGDVLVFLTGQEEIEACCELLQERCRRLGSKISELLVLPIYANLPSDMQAKIFNPTPPGARKVVVATNIAETSLTIDGIIYVIDPGFCKQKSYNAKTGMESLIVTPCSRASANQRAGRAGRVAAGKCFRLYTAWAFKHEMEETTVPEIQRTNLGNVVLLLKSLGINDLIHFDFMDPPPHETLVLALEQLYALGALNHLGELTKLGRRMAELPVDPMLSKMILASEQYKCSEEVLTIAAMLSVNNSIFYRPKDKVVHADNARMNFVVPGGDHLVLLNVYTQWVESGYSTQWCFENFIQFRSMKRARDVRDQLEGLMDRIEVELCSSNGDSM-PIRKAVTAGYFYHTA-RLSKGGYKTVKHQQTVYVHPNSSLFEEQPRWMIYHELVFTTKEFMRQVIEIESGWLLE 1023
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Xenopus
Match: rps15a (ribosomal protein S15a [Source:Xenbase;Acc:XB-GENE-981311]) HSP 1 Score: 529.25 bits (1362), Expect = 2.328e-179 Identity = 271/616 (43.99%), Postives = 386/616 (62.66%), Query Frame = 3 Query: 180 KELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNL--------ESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYR-AMKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEF 1991 + LPI + K+ +++ V +NQI+I+ G TGSGKTTQI QYL EAG IG TQPRR+AA+++A RV++E CLG EVGY +RF +S T IKYMTDG+LL +CL DP L +Y ++M+DEAHERT+ TDVL GL+K +R D+K+++TSAT+ KFS YF AP+ + G+ Y V+I+Y EP + + ++Q IH GDIL+FLTGQE+I+ C+ L + L +LP+Y AL + Q IF PA PG RKV+++TNIAETS+TIDGI +V+D G+VKQ +++S++GID L ISQ QA QR GRAGRT G CYRLYTE YR M PEI R NL T L + +GI D +SF F+D+P ETL + +L L +D+ +T LG+ + +FP+EP + K L S C E++TI++M+S +NVF RPK +D K KF +EGD L Y +W N+ S WCY+NF+ +++ + +R Q++G++ R + V ++K++ F++N + + Y ++QQV+Y+HPSS L N ++Y+E+V T K YMR + T+ L EF Sbjct: 39 ESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTTRGKIGCTQPRRVAAMSVAKRVSEEYGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRPDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLDASLITVMQ-IHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKATV-RVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTIDPRWLVEF 652
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Xenopus
Match: rps15a (ribosomal protein S15a [Source:Xenbase;Acc:XB-GENE-981311]) HSP 1 Score: 523.087 bits (1346), Expect = 5.662e-177 Identity = 271/617 (43.92%), Postives = 383/617 (62.07%), Query Frame = 3 Query: 180 KELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNL--------ESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYR-AMKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQ-LMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEF 1991 + LPI + K+ +++ V +NQI+I+ G TGSGKTTQI QYL EAG IG TQPRR+AA+++A RV++E CLG EVGY +RF +S T IKYMTDG+LL +CL DP L +Y ++M+DEAHERT+ TDVL GL+K +R D+K+++TSAT+ KFS YF AP+ + G+ Y V+I+Y EP + + ++Q IH GDIL+FLTGQE+I+ C+ L + L +LP+Y AL + Q IF PA PG RKV+++TNIAETS+TIDGI +V+D G+VKQ +++S++GID L ISQ QA QR GRAGRT G CYRLYTE YR M PEI R NL T L + +GI D +SF F+D+P ETL + +L L +D+ +T LG+ + +FP+EP + K L S C E++TI++M+S +NVF RPK +D K KF +EGD L Y +W N+ S WCY+NF+ +++ + +R Q L L + K + ++K++ F++N + + Y ++QQV+Y+HPSS L N ++Y+E+V T K YMR + T+ L EF Sbjct: 39 ESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTTRGKIGCTQPRRVAAMSVAKRVSEEYGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRPDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLDASLITVMQ-IHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQILFHLCRHKLDVVSCGKATV--RVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTIDPRWLVEF 652
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Xenopus
Match: rps15a (ribosomal protein S15a [Source:Xenbase;Acc:XB-GENE-981311]) HSP 1 Score: 523.857 bits (1348), Expect = 9.992e-177 Identity = 273/630 (43.33%), Postives = 390/630 (61.90%), Query Frame = 3 Query: 180 KELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNL--------ESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYR-AMKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEFPKESKKIGYNSSIS 2033 + LPI + K+ +++ V +NQI+I+ G TGSGKTTQI QYL EAG IG TQPRR+AA+++A RV++E CLG EVGY +RF +S T IKYMTDG+LL +CL DP L +Y ++M+DEAHERT+ TDVL GL+K +R D+K+++TSAT+ KFS YF AP+ + G+ Y V+I+Y EP + + ++Q IH GDIL+FLTGQE+I+ C+ L + L +LP+Y AL + Q IF PA PG RKV+++TNIAETS+TIDGI +V+D G+VKQ +++S++GID L ISQ QA QR GRAGRT G CYRLYTE YR M PEI R NL T L + +GI D +SF F+D+P ETL + +L L +D+ +T LG+ + +FP+EP + K L S C E++TI++M+S +NVF RPK D K KF +EGD L Y +W N+ S WCY+NF+ +++ + +R Q++G++ R + V ++K++ F++N + + Y ++QQV+Y+HPSS L N ++Y+E+V T K YMR + T+ L EF K+ + +S Sbjct: 39 ESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTTRGKIGCTQPRRVAAMSVAKRVSEEYGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRPDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLDASLITVMQ-IHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKVRI--PDQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKATV-RVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTIDPRWLVEFAPAFFKVSDPTKLS 664
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Xenopus
Match: rps15a (ribosomal protein S15a [Source:Xenbase;Acc:XB-GENE-981311]) HSP 1 Score: 521.931 bits (1343), Expect = 2.547e-176 Identity = 272/636 (42.77%), Postives = 388/636 (61.01%), Query Frame = 3 Query: 180 KELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNL--------ESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYR-AMKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVD------SIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEFPKESKKIGYNSSIS 2033 + LPI + K+ +++ V +NQI+I+ G TGSGKTTQI QYL EAG IG TQPRR+AA+++A RV++E CLG EVGY +RF +S T IKYMTDG+LL +CL DP L +Y ++M+DEAHERT+ TDVL GL+K +R D+K+++TSAT+ KFS YF AP+ + G+ Y V+I+Y EP + + ++Q IH GDIL+FLTGQE+I+ C+ L + L +LP+Y AL + Q IF PA PG RKV+++TNIAETS+TIDGI +V+D G+VKQ +++S++GID L ISQ QA QR GRAGRT G CYRLYTE YR M PEI R NL T L + +GI D +SF F+D+P ETL + +L L +D+ +T LG+ + +FP+EP + K L S C E++TI++M+S +NVF RPK +D K KF +EGD L Y +W N+ S WCY+NF+ +++ + +R Q+ L++V ++K++ F++N + + Y ++QQV+Y+HPSS L N ++Y+E+V T K YMR + T+ L EF K+ + +S Sbjct: 39 ESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTTRGKIGCTQPRRVAAMSVAKRVSEEYGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRPDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLDASLITVMQ-IHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQM-------------HKLDVVSCGKATVRVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTIDPRWLVEFAPAFFKVSDPTKLS 660
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Xenopus
Match: rps15a (ribosomal protein S15a [Source:Xenbase;Acc:XB-GENE-981311]) HSP 1 Score: 520.005 bits (1338), Expect = 1.833e-175 Identity = 270/622 (43.41%), Postives = 383/622 (61.58%), Query Frame = 3 Query: 180 KELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNL--------ESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYR-AMKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVD------SIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEF 1991 + LPI + K+ +++ V +NQI+I+ G TGSGKTTQI QYL EAG IG TQPRR+AA+++A RV++E CLG EVGY +RF +S T IKYMTDG+LL +CL DP L +Y ++M+DEAHERT+ TDVL GL+K +R D+K+++TSAT+ KFS YF AP+ + G+ Y V+I+Y EP + + ++Q IH GDIL+FLTGQE+I+ C+ L + L +LP+Y AL + Q IF PA PG RKV+++TNIAETS+TIDGI +V+D G+VKQ +++S++GID L ISQ QA QR GRAGRT G CYRLYTE YR M PEI R NL T L + +GI D +SF F+D+P ETL + +L L +D+ +T LG+ + +FP+EP + K L S C E++TI++M+S +NVF RPK +D K KF +EGD L Y +W N+ S WCY+NF+ +++ + +R Q+ L++V ++K++ F++N + + Y ++QQV+Y+HPSS L N ++Y+E+V T K YMR + T+ L EF Sbjct: 39 ESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTTRGKIGCTQPRRVAAMSVAKRVSEEYGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRPDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLDASLITVMQ-IHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQM-------------HKLDVVSCGKATVRVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTIDPRWLVEF 646
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Mouse
Match: Dhx8 (DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Source:MGI Symbol;Acc:MGI:1306823]) HSP 1 Score: 531.561 bits (1368), Expect = 3.029e-174 Identity = 271/614 (44.14%), Postives = 387/614 (63.03%), Query Frame = 3 Query: 186 LPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNL--------ESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYR-AMKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEF 1991 LPI + K+ +++ V +NQI+I+ G TGSGKTTQI QYL EAG + IG TQPRR+AA+++A RV++E CLG EVGY +RF +S T IKYMTDG+LL +CL DP L +Y ++M+DEAHERT+ TDVL GL+K +R D+K+++TSAT+ KFS YF AP+ + G+ Y V+I+Y EP + + ++Q IH GDIL+FLTGQE+I+ C+ L + L +LP+Y AL + Q IF PA PG RKV+++TNIAETS+TIDGI +V+D G+VKQ +++S++GID L ISQ QA QR GRAGRT G CYRLYTE YR M PEI R NL T L + +GI D +SF F+D+P ETL + +L L +D+ +T LG+ + +FP+EP + K L S C E++TI++M+S +NVF RPK +D K KF +EGD L Y +W N+ S WCY+NF+ +++ + +R Q++G++ R + + V ++K++ F++N + + Y ++QQV+Y+HPSS L N ++Y+E+V T K YMR + T+ L EF Sbjct: 536 LPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRRVAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLDASLITVMQ-IHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKSTV-RVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTIDPRWLVEF 1147
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Mouse
Match: Dhx8 (DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Source:MGI Symbol;Acc:MGI:1306823]) HSP 1 Score: 531.176 bits (1367), Expect = 2.347e-173 Identity = 271/614 (44.14%), Postives = 387/614 (63.03%), Query Frame = 3 Query: 186 LPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNL--------ESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYR-AMKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEF 1991 LPI + K+ +++ V +NQI+I+ G TGSGKTTQI QYL EAG + IG TQPRR+AA+++A RV++E CLG EVGY +RF +S T IKYMTDG+LL +CL DP L +Y ++M+DEAHERT+ TDVL GL+K +R D+K+++TSAT+ KFS YF AP+ + G+ Y V+I+Y EP + + ++Q IH GDIL+FLTGQE+I+ C+ L + L +LP+Y AL + Q IF PA PG RKV+++TNIAETS+TIDGI +V+D G+VKQ +++S++GID L ISQ QA QR GRAGRT G CYRLYTE YR M PEI R NL T L + +GI D +SF F+D+P ETL + +L L +D+ +T LG+ + +FP+EP + K L S C E++TI++M+S +NVF RPK +D K KF +EGD L Y +W N+ S WCY+NF+ +++ + +R Q++G++ R + + V ++K++ F++N + + Y ++QQV+Y+HPSS L N ++Y+E+V T K YMR + T+ L EF Sbjct: 589 LPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRRVAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLDASLITVMQ-IHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKSTV-RVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTIDPRWLVEF 1200
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Mouse
Match: Dhx16 (DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Source:MGI Symbol;Acc:MGI:1916442]) HSP 1 Score: 491.5 bits (1264), Expect = 2.845e-160 Identity = 264/632 (41.77%), Postives = 384/632 (60.76%), Query Frame = 3 Query: 135 LSFLTQQLQGIKVSDKELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAG-INNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNLE--------SIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYRAMKQETT-PEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERN-VFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTE 1988 LS QQ + I+ + LP+ +++ ++ + N+Q++II G TGSGKTTQIPQYLFE G I TQPRR+AA+++A+RVA+EM LG EVGY +RF +S T ++YMTDG+LL + L +P L Y V+M+DEAHERT+ TD+L GLIK +A R +LKVL+ SAT+ +FS +F APV G+ + V I Y P + + +++Q IH GDIL+FLTGQE+IE C+ L+ I+ L VLP+Y L D Q IF+P PG RKV+V+TNIAETS+TI+GI +V+D G+ KQ ++ R+G++SLT S+ A QR GRAGR G C+RLYT Y+ +ETT PEI R +L L + +GI D M F F+D P +ETL L +L L ++ ++T G+ + + PV+P + K + AS KY C E++T+ AM+S N +F RPK V +D ++ FF GD + LN Y W+E+ S QWCY+NFV F++M + VR QL GL++R + V ++K++ ++ + R ++ Y QQ +++HP+S L +LY+E+V T K +MR ++ + S L E Sbjct: 385 LSAQAQQKESIQAVRRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTKKGMKIACTQPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATLDTARFSAFFDDAPVFRIPGRRFPVDIFYTKAPEADYLEACVVSVLQ-IHVTQPPGDILVFLTGQEEIEAACEMLQDRCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSLTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETLLLALEQLYALGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCYENFVQFRSMRRARDVREQLEGLLERVEVGLTSCQGDYV-RVRKAITSGYFYHTA-RLTRSGYRTVKQQQTVFIHPNSSLFEQQPRWLLYHELVLTTKEFMRQVLEIESSWLLE 1013
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Mouse
Match: Dhx15 (DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Source:MGI Symbol;Acc:MGI:1099786]) HSP 1 Score: 467.618 bits (1202), Expect = 6.124e-154 Identity = 249/614 (40.55%), Postives = 373/614 (60.75%), Query Frame = 3 Query: 183 ELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFE---AGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNLE--------SIQSLTVLPLYGALDFDAQQDIFKPAEPGK------RKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYRA-MKQETTPEIYRRNLYGTYLKIAGIGIDPM-SFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVD---SIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMR 1952 +LP+ +YKD + +Q ++ G TGSGKTTQIPQ+ E + + + TQPRR+AA+++A RVA EM LG EVGY +RF SS T +KYMTDG+LL + + DP L YGV+++DEAHERT+ TD+L+G++K + +R+DLKV++ SAT+ KF YF P+++ G+ + V+I Y EP + I ++Q E+GD+LLFLTGQE+I+E C+ ++ + + ++PLY L QQ IF+P P K RKV+VSTNIAETS+TIDG+ FVID G+ KQ +++ R ++SL IS+ A QR GRAGRT G C+RLYTE+ Y+ M+ T PEI R NL L++ +GID + F F+D P ETL + L L L +++ +TELG + +FP++P++ K + AS Y C EV++I AM+S F+RP ++ +D +K +F +GD LN Y A+ +N +S QWCYDNF+N++++ D VR QL ++ R + +D D +I+K+L+ ++ + + G Y+ + QV+ +HPS+ L + +LY E V T K Y+R Sbjct: 136 QLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVEYMRSLPGPKRGVACTQPRRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSAKTILKYMTDGMLLREAMNDPLLERYGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKFQIYFDNCPLLTIPGRTHPVEIFYTPEPERDYLEAAIRTVIQIHMCEEEEGDLLLFLTGQEEIDEACKRIKREVDDLGPEVGDIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGRTRPGKCFRLYTEKAYKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLAALNDDGDLTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVLSITAMLSVPQCFVRPTEAKKAADEAKMRFAHIDGDHLTLLNVYHAFKQNHESVQWCYDNFINYRSLMSADNVRQQLSRIMDRFNLPRRSTDFTSRDYYINIRKALVTGYFMQVAHLERTGHYLTVKDNQVVQLHPSTVL-DHKPEWVLYNEFVLTTKNYIR 748
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Mouse
Match: Dhx15 (DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Source:MGI Symbol;Acc:MGI:1099786]) HSP 1 Score: 445.277 bits (1144), Expect = 1.736e-146 Identity = 233/566 (41.17%), Postives = 348/566 (61.48%), Query Frame = 3 Query: 183 ELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFE---AGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNLE--------SIQSLTVLPLYGALDFDAQQDIFKPAEPGK------RKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYRA-MKQETTPEIYRRNLYGTYLKIAGIGIDPM-SFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVD---SIKKSLIPSFYKNI 1808 +LP+ +YKD + +Q ++ G TGSGKTTQIPQ+ E + + + TQPRR+AA+++A RVA EM LG EVGY +RF SS T +KYMTDG+LL + + DP L YGV+++DEAHERT+ TD+L+G++K + +R+DLKV++ SAT+ KF YF P+++ G+ + V+I Y EP + I ++Q E+GD+LLFLTGQE+I+E C+ ++ + + ++PLY L QQ IF+P P K RKV+VSTNIAETS+TIDG+ FVID G+ KQ +++ R ++SL IS+ A QR GRAGRT G C+RLYTE+ Y+ M+ T PEI R NL L++ +GID + F F+D P ETL + L L L +++ +TELG + +FP++P++ K + AS Y C EV++I AM+S F+RP ++ +D +K +F +GD LN Y A+ +N +S QWCYDNF+N++++ D VR QL ++ R + +D D +I+K+L+ ++ + Sbjct: 136 QLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVEYMRSLPGPKRGVACTQPRRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSAKTILKYMTDGMLLREAMNDPLLERYGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKFQIYFDNCPLLTIPGRTHPVEIFYTPEPERDYLEAAIRTVIQIHMCEEEEGDLLLFLTGQEEIDEACKRIKREVDDLGPEVGDIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGRTRPGKCFRLYTEKAYKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLAALNDDGDLTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVLSITAMLSVPQCFVRPTEAKKAADEAKMRFAHIDGDHLTLLNVYHAFKQNHESVQWCYDNFINYRSLMSADNVRQQLSRIMDRFNLPRRSTDFTSRDYYINIRKALVTGYFMQV 701
BLAST of ATP-dependent RNA helicase DHX8 vs. UniProt/SwissProt
Match: sp|Q14562|DHX8_HUMAN (ATP-dependent RNA helicase DHX8 OS=Homo sapiens OX=9606 GN=DHX8 PE=1 SV=1) HSP 1 Score: 530.791 bits (1366), Expect = 1.102e-172 Identity = 271/614 (44.14%), Postives = 387/614 (63.03%), Query Frame = 3 Query: 186 LPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNL--------ESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYR-AMKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEF 1991 LPI + K+ +++ V +NQI+I+ G TGSGKTTQI QYL EAG + IG TQPRR+AA+++A RV++E CLG EVGY +RF +S T IKYMTDG+LL +CL DP L +Y ++M+DEAHERT+ TDVL GL+K +R D+K+++TSAT+ KFS YF AP+ + G+ Y V+I+Y EP + + ++Q IH GDIL+FLTGQE+I+ C+ L + L +LP+Y AL + Q IF PA PG RKV+++TNIAETS+TIDGI +V+D G+VKQ +++S++GID L ISQ QA QR GRAGRT G CYRLYTE YR M PEI R NL T L + +GI D +SF F+D+P ETL + +L L +D+ +T LG+ + +FP+EP + K L S C E++TI++M+S +NVF RPK +D K KF +EGD L Y +W N+ S WCY+NF+ +++ + +R Q++G++ R + + V ++K++ F++N + + Y ++QQV+Y+HPSS L N ++Y+E+V T K YMR + T+ L EF Sbjct: 565 LPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRRVAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLDASLITVMQ-IHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKSTV-RVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTIDPRWLVEF 1176
BLAST of ATP-dependent RNA helicase DHX8 vs. UniProt/SwissProt
Match: sp|A2A4P0|DHX8_MOUSE (ATP-dependent RNA helicase DHX8 OS=Mus musculus OX=10090 GN=Dhx8 PE=2 SV=1) HSP 1 Score: 531.176 bits (1367), Expect = 1.642e-172 Identity = 271/614 (44.14%), Postives = 387/614 (63.03%), Query Frame = 3 Query: 186 LPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNL--------ESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYR-AMKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEF 1991 LPI + K+ +++ V +NQI+I+ G TGSGKTTQI QYL EAG + IG TQPRR+AA+++A RV++E CLG EVGY +RF +S T IKYMTDG+LL +CL DP L +Y ++M+DEAHERT+ TDVL GL+K +R D+K+++TSAT+ KFS YF AP+ + G+ Y V+I+Y EP + + ++Q IH GDIL+FLTGQE+I+ C+ L + L +LP+Y AL + Q IF PA PG RKV+++TNIAETS+TIDGI +V+D G+VKQ +++S++GID L ISQ QA QR GRAGRT G CYRLYTE YR M PEI R NL T L + +GI D +SF F+D+P ETL + +L L +D+ +T LG+ + +FP+EP + K L S C E++TI++M+S +NVF RPK +D K KF +EGD L Y +W N+ S WCY+NF+ +++ + +R Q++G++ R + + V ++K++ F++N + + Y ++QQV+Y+HPSS L N ++Y+E+V T K YMR + T+ L EF Sbjct: 589 LPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRRVAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLDASLITVMQ-IHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKSTV-RVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTIDPRWLVEF 1200
BLAST of ATP-dependent RNA helicase DHX8 vs. UniProt/SwissProt
Match: sp|A1Z9L3|DHX8_DROME (ATP-dependent RNA helicase DHX8 OS=Drosophila melanogaster OX=7227 GN=pea PE=1 SV=1) HSP 1 Score: 517.694 bits (1332), Expect = 1.919e-167 Identity = 272/616 (44.16%), Postives = 384/616 (62.34%), Query Frame = 3 Query: 180 KELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNL--------ESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYR-AMKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEF 1991 + LPI + +D +IK V +NQI+I+ G TGSGKTTQI QYL E G IG TQPRR+AA+++A RVA+E LG EVGY +RF +S T IKYMTDG+LL +CL + +L Y V+M+DEAHERT+ TDVL GL+K +R +LK+++TSAT+ KFS YF AP+ + G+ + V+++Y EP + + ++Q IH GDILLFLTGQE+I+ C+ L + L +LP+Y AL + Q IF PA G RKV+++TNIAETS+TIDGI +V+D G+VKQ +++S++G+DSL ISQ A QR GRAGRT G YRLYTE YR M PEI R NL T L++ +GI D + F F+D+P E+L L +L L +D+ +T LG+ + +FP+EP + K L S C E++TI++M+S +NVF RPK +D K KF +EGD L Y +W N+ S WCY+NFV +T+++ VR QL+G++ R + + N V I+K++ F++N + + Y ++ QV+Y+HPSS L N ++Y+E+VQT K YMR + T+ L EF Sbjct: 584 QSLPIYKLRDDLIKAVTDNQILIVIGETGSGKTTQITQYLGECGFTARGKIGCTQPRRVAAMSVAKRVAEEYGCRLGQEVGYTIRFEDCTSPETIIKYMTDGMLLRECLMEAELKSYSVIMLDEAHERTIHTDVLFGLLKTAVQKRPELKLIVTSATLDAVKFSQYFFKAPIFTIPGRTFPVEVLYTKEPETDYLDASLITVMQ-IHLREPPGDILLFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPAGSRKVVIATNIAETSLTIDGIFYVVDPGFVKQKVYNSKTGMDSLVVTPISQAAAKQRAGRAGRTGPGKTYRLYTERAYRDEMLPTPVPEIQRTNLATTVLQLKTMGINDLLHFDFMDAPPVESLVMALEQLHSLSALDDEGLLTRLGRRMAEFPLEPNLSKMLIMSVALQCSDEILTIVSMLSVQNVFYRPKDKQALADQKKAKFNQAEGDHLTLLAVYNSWKNNKFSNAWCYENFVQIRTLKRSQDVRKQLLGIMDRHKLDVVSAGKNSV-RIQKAICSGFFRNAAKKDPQEGYRTLVDSQVVYIHPSSALFNRQPEWVIYHELVQTTKEYMREVTTIDPKWLVEF 1197
BLAST of ATP-dependent RNA helicase DHX8 vs. UniProt/SwissProt
Match: sp|Q54F05|DHX8_DICDI (ATP-dependent RNA helicase dhx8 OS=Dictyostelium discoideum OX=44689 GN=dhx8 PE=3 SV=1) HSP 1 Score: 500.36 bits (1287), Expect = 1.064e-161 Identity = 267/623 (42.86%), Postives = 379/623 (60.83%), Query Frame = 3 Query: 159 QGIKVSDKELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNL--------ESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYR-AMKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEF 1991 + IK + LPI ++ ++ V +Q++++ G TGSGKTTQ+ QYL EAG IG TQPRR+AA++++ RVA+E LG EVGY +RF +S T IK+MTDGILL +CL DP L Y V+++DEAHERT+ TDVL GL+K RR +LKVLITSAT+ EKFS YF A + G+ + V I Y +P + + ++Q IH GDILLFLTGQE+I+ CQ L ++ L +LP+Y AL + Q IF+PA PG RKV+++TNIAETS+TIDGI +VID G+ KQ F+ ++G+DSL ISQ A QR GRAGRT G CYRLYTE ++ M + PEI R NL T L + +GI D ++F F+D P +TL + +L L +DE +T LG+ + +FP++P++ K L AS C E++T++AM+S +NVF RPK+ +D K KFF EGD LN Y++W ++ S WC++NFV +++ + VR QL+ ++ R + + N I+K++ F+ N + Y + Q +Y+HPSS L N ++Y+E+V T K YMR + T+ L E Sbjct: 499 RSIKEQRESLPIFPLREAFLQAVSEHQLLVVIGETGSGKTTQMAQYLAEAGYGTRGKIGCTQPRRVAAMSVSKRVAEEFGCQLGQEVGYAIRFEDCTSPETIIKFMTDGILLRECLLDPNLSAYSVIILDEAHERTISTDVLFGLLKQALQRRPELKVLITSATLEAEKFSKYFMNAQLFIIPGRTFPVDIRYTKDPEADYLDASLITVMQ-IHLSEPPGDILLFLTGQEEIDAACQILYERMKSLGSNVPDLIILPVYSALPSEMQTKIFEPAPPGSRKVVIATNIAETSLTIDGIYYVIDPGFSKQKCFNPKNGMDSLVVAPISQAAARQRSGRAGRTGPGKCYRLYTESAFKNEMLASSIPEIQRTNLGNTVLTMKAMGINDLLNFDFMDPPPVQTLVSAMEQLYSLGALDEEGLLTRLGRKMAEFPLDPQLSKMLIASVDLGCSDEILTVVAMLSVQNVFYRPKEKQALADQKKAKFFQPEGDHLTLLNVYESWKNSKFSNPWCFENFVQARSLRRAQDVRKQLITIMDRYKLDIISAGRNYT-KIQKAICSGFFANASKKDPNEGYKTLVEGQPVYIHPSSTLFNRNPDWVIYHELVMTTKEYMREVCTIDPKWLVEL 1119
BLAST of ATP-dependent RNA helicase DHX8 vs. UniProt/SwissProt
Match: sp|O42643|PRP22_SCHPO (Pre-mRNA-splicing factor ATP-dependent RNA helicase prp22 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=prp22 PE=1 SV=1) HSP 1 Score: 499.975 bits (1286), Expect = 2.154e-161 Identity = 270/637 (42.39%), Postives = 393/637 (61.70%), Query Frame = 3 Query: 186 LPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINND-KTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNL--------ESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYR-AMKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKR-KFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKS-KGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEFPKESKKIGYNSSISL*TKNL 2051 LP+ + + ++ V NQI+++ G TGSGKTTQI QYL E G +D K IG TQPRR+AA+++A RVA+E+ +G EVGY +RF K+S T+IKYMTDG+L +CL DP L +Y V+++DEAHERTV TDVL GL+K +R DLK+++TSAT+ E+FS+YF P+ + G+ Y V+I+Y +P + + ++Q IH GDIL+FLTGQE+I+ C+ L +SI L +LP+Y AL + Q IF+PA PG RKV+++TNIAETS+TIDGI +V+D G+VKQ+ FD + G+DSL ISQ QA QR GRAGRT G CYRLYTE YR M PEI R+NL T L + +GI D ++F F+D P +T+ L L L +D+ +T LG+ + DFP+EP++ K L S + C E+++I+AM+S N++ RP++ ++D + +F + E D LN Y W NR S WCY++++ + M + + VR QL+ L+ R + P S + I ++L ++ N+ R S +G Y + +YMHPS L + ++Y+E++QT K YM + T++ L E K + +S KNL Sbjct: 510 LPVFKLRKQFLEAVSKNQILVLLGETGSGKTTQITQYLAEEGYTSDSKMIGCTQPRRVAAMSVAKRVAEEVGCRVGEEVGYTIRFEDKTSRMTQIKYMTDGMLQRECLVDPLLSKYSVIILDEAHERTVATDVLFGLLKGTVLKRPDLKLIVTSATLDAERFSSYFYKCPIFTIPGRSYPVEIMYTKQPEADYLDAALMTVMQ-IHLSEGPGDILVFLTGQEEIDTSCEILYERSKMLGDSIPELVILPVYSALPSEIQSRIFEPAPPGGRKVVIATNIAETSLTIDGIYYVVDPGFVKQSCFDPKLGMDSLIVTPISQAQARQRSGRAGRTGPGKCYRLYTESAYRNEMLPSPIPEIQRQNLSHTILMLKAMGINDLLNFDFMDPPPAQTMIAALQNLYALSALDDEGLLTPLGRKMADFPMEPQLSKVLITSVELGCSEEMLSIIAMLSVPNIWSRPREKQQEADRQRAQFANPESDHLTLLNVYTTWKMNRCSDNWCYEHYIQARGMRRAEDVRKQLIRLMDRYRHPVV--SCGRKRELILRALCSGYFTNVAKRDSHEGCYKTIVENAPVYMHPSGVLFGKAAEWVIYHELIQTSKEYMHTVSTVNPKWLVEVAPTFFKFANANQVSKTKKNL 1143
BLAST of ATP-dependent RNA helicase DHX8 vs. TrEMBL
Match: A0A4Y2HUD2 (ATP-dependent RNA helicase DHX8 OS=Araneus ventricosus OX=182803 GN=DHX8_0 PE=4 SV=1) HSP 1 Score: 538.11 bits (1385), Expect = 2.195e-179 Identity = 281/622 (45.18%), Postives = 391/622 (62.86%), Query Frame = 3 Query: 180 KELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNL--------ESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYR-AMKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVD------SIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEF 1991 + LPI + KD +IK V +NQI+I+ G TGSGKTTQ+ QYL EAG IG TQPRR+AA+++A RVA+E LG EVGY +RF +S T IKYMTDG+LL +CL DP L Y V+M+DEAHERT+ TDVL GL+K RR +LK+++TSAT+ KFS YF AP+ + G+ Y V+I+Y EP + + ++Q IH GDILLFLTGQE+I+ C+ L + L +LP+Y AL + Q IF+PA PG RKV+++TNIAETS+TIDGI +V+D G+VKQN+++S++G+DSL ISQ QA QR GRAGRT G CYRLYTE +YR M PEI R NL T L++ +GI D +SF F+D+P E+L L +L L +D+ +T LG+ + +FP+EP + K L S C E++TI++M+S +NVF RPK +D K KF EGD L Y +W N+ S WCY+NFV +T+++ VR QL+G++ R L++V ++K++ F++N + + Y ++ QV+Y+HPSS L N ++Y+E+VQT K YMR + T+ + EF Sbjct: 39 QSLPIYKLKDDLIKAVTDNQILIVIGETGSGKTTQMTQYLAEAGFTARGKIGCTQPRRVAAMSVAKRVAEEFGCRLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLVDPDLKSYAVVMLDEAHERTIHTDVLFGLLKNAVKRRPELKLIVTSATLDAVKFSQYFFEAPIFTIPGRTYPVEILYTKEPENDYLDASLITVMQ-IHLTEPPGDILLFLTGQEEIDTACEILYERMKSLGPEVPELIILPVYSALPSEMQTRIFEPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQNVYNSKTGMDSLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERSYRDEMLTTPVPEIQRTNLAHTVLQLKAMGINDLLSFDFMDAPPPESLIMALEQLHSLSALDDEGLLTRLGRRMAEFPMEPNLSKMLIMSVHLACSEEILTIVSMLSVQNVFYRPKDKQALADQKKAKFNQPEGDHLTLLAVYNSWKNNKFSNAWCYENFVQIRTLKRAQDVRKQLLGIMDRH-------KLDVVSCGKTTARVQKAICSGFFRNAAKKDPQEGYRTLVDGQVVYIHPSSALFNRQPEWVVYHELVQTTKEYMREVTTIDPKWMVEF 652
BLAST of ATP-dependent RNA helicase DHX8 vs. TrEMBL
Match: A0A091E849 (ATP-dependent RNA helicase DHX8 (Fragment) OS=Corvus brachyrhynchos OX=85066 GN=N302_08224 PE=4 SV=1) HSP 1 Score: 530.791 bits (1366), Expect = 2.401e-177 Identity = 272/616 (44.16%), Postives = 387/616 (62.82%), Query Frame = 3 Query: 180 KELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNL--------ESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYR-AMKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEF 1991 + LPI + K+ +I+ V +NQI+I+ G TGSGKTTQI QYL EAG + IG TQPRR+AA+++A RV++E CLG EVGY +RF +S T IKYMTDG+LL +CL DP L +Y ++M+DEAHERT+ TDVL GL+K +R D+K+++TSAT+ KFS YF AP+ + G+ Y V+I+Y EP + + ++Q IH GDIL+FLTGQE+I+ C+ L + L +LP+Y AL + Q IF PA PG RKV+++TNIAETS+TIDGI +V+D G+VKQ +++S++GID L ISQ QA QR GRAGRT G CYRLYTE YR M PEI R NL T L + +GI D +SF F+D+P ETL + +L L +D+ +T LG+ + +FP+EP + K L S C E++TI++M+S +NVF RPK +D K KF +EGD L Y +W N+ S WCY+NF+ +++ + +R Q++G++ R + V ++K++ F++N + + Y ++QQV+Y+HPSS L N ++Y+E+V T K YMR + T+ L EF Sbjct: 14 ESLPIFRLKEQLIQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRRVAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLDASLITVMQ-IHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKATV-RVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTIDPRWLVEF 627
BLAST of ATP-dependent RNA helicase DHX8 vs. TrEMBL
Match: A0A093FTV2 (ATP-dependent RNA helicase DHX8 (Fragment) OS=Gavia stellata OX=37040 GN=N328_11365 PE=4 SV=1) HSP 1 Score: 530.791 bits (1366), Expect = 2.401e-177 Identity = 272/616 (44.16%), Postives = 387/616 (62.82%), Query Frame = 3 Query: 180 KELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNL--------ESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYR-AMKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEF 1991 + LPI + K+ +I+ V +NQI+I+ G TGSGKTTQI QYL EAG + IG TQPRR+AA+++A RV++E CLG EVGY +RF +S T IKYMTDG+LL +CL DP L +Y ++M+DEAHERT+ TDVL GL+K +R D+K+++TSAT+ KFS YF AP+ + G+ Y V+I+Y EP + + ++Q IH GDIL+FLTGQE+I+ C+ L + L +LP+Y AL + Q IF PA PG RKV+++TNIAETS+TIDGI +V+D G+VKQ +++S++GID L ISQ QA QR GRAGRT G CYRLYTE YR M PEI R NL T L + +GI D +SF F+D+P ETL + +L L +D+ +T LG+ + +FP+EP + K L S C E++TI++M+S +NVF RPK +D K KF +EGD L Y +W N+ S WCY+NF+ +++ + +R Q++G++ R + V ++K++ F++N + + Y ++QQV+Y+HPSS L N ++Y+E+V T K YMR + T+ L EF Sbjct: 14 ESLPIFRLKEQLIQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRRVAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLDASLITVMQ-IHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKATV-RVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTIDPRWLVEF 627
BLAST of ATP-dependent RNA helicase DHX8 vs. TrEMBL
Match: A0A093PX93 (ATP-dependent RNA helicase DHX8 (Fragment) OS=Manacus vitellinus OX=328815 GN=N305_13516 PE=4 SV=1) HSP 1 Score: 530.791 bits (1366), Expect = 2.401e-177 Identity = 272/616 (44.16%), Postives = 387/616 (62.82%), Query Frame = 3 Query: 180 KELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNL--------ESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYR-AMKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEF 1991 + LPI + K+ +I+ V +NQI+I+ G TGSGKTTQI QYL EAG + IG TQPRR+AA+++A RV++E CLG EVGY +RF +S T IKYMTDG+LL +CL DP L +Y ++M+DEAHERT+ TDVL GL+K +R D+K+++TSAT+ KFS YF AP+ + G+ Y V+I+Y EP + + ++Q IH GDIL+FLTGQE+I+ C+ L + L +LP+Y AL + Q IF PA PG RKV+++TNIAETS+TIDGI +V+D G+VKQ +++S++GID L ISQ QA QR GRAGRT G CYRLYTE YR M PEI R NL T L + +GI D +SF F+D+P ETL + +L L +D+ +T LG+ + +FP+EP + K L S C E++TI++M+S +NVF RPK +D K KF +EGD L Y +W N+ S WCY+NF+ +++ + +R Q++G++ R + V ++K++ F++N + + Y ++QQV+Y+HPSS L N ++Y+E+V T K YMR + T+ L EF Sbjct: 14 ESLPIFRLKEQLIQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRRVAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLDASLITVMQ-IHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKATV-RVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTIDPRWLVEF 627
BLAST of ATP-dependent RNA helicase DHX8 vs. TrEMBL
Match: A0A093GEK7 (ATP-dependent RNA helicase DHX8 (Fragment) OS=Dryobates pubescens OX=118200 GN=N307_15035 PE=4 SV=1) HSP 1 Score: 530.791 bits (1366), Expect = 2.401e-177 Identity = 272/616 (44.16%), Postives = 387/616 (62.82%), Query Frame = 3 Query: 180 KELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNL--------ESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYR-AMKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEF 1991 + LPI + K+ +I+ V +NQI+I+ G TGSGKTTQI QYL EAG + IG TQPRR+AA+++A RV++E CLG EVGY +RF +S T IKYMTDG+LL +CL DP L +Y ++M+DEAHERT+ TDVL GL+K +R D+K+++TSAT+ KFS YF AP+ + G+ Y V+I+Y EP + + ++Q IH GDIL+FLTGQE+I+ C+ L + L +LP+Y AL + Q IF PA PG RKV+++TNIAETS+TIDGI +V+D G+VKQ +++S++GID L ISQ QA QR GRAGRT G CYRLYTE YR M PEI R NL T L + +GI D +SF F+D+P ETL + +L L +D+ +T LG+ + +FP+EP + K L S C E++TI++M+S +NVF RPK +D K KF +EGD L Y +W N+ S WCY+NF+ +++ + +R Q++G++ R + V ++K++ F++N + + Y ++QQV+Y+HPSS L N ++Y+E+V T K YMR + T+ L EF Sbjct: 14 ESLPIFRLKEQLIQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRRVAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLDASLITVMQ-IHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKATV-RVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTIDPRWLVEF 627
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Cavefish
Match: dhx8 (DEAH-box helicase 8 [Source:NCBI gene;Acc:103035799]) HSP 1 Score: 529.25 bits (1362), Expect = 3.462e-173 Identity = 272/614 (44.30%), Postives = 385/614 (62.70%), Query Frame = 3 Query: 186 LPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNL--------ESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYR-AMKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEF 1991 LPI + K+ +I+ V +NQI+I+ G TGSGKTTQI QYL EAG IG TQPRR+AA+++A RV++E CLG EVGY +RF +S T IKYMTDG+LL +CL DP L +Y ++M+DEAHERT+ TDVL GL+K +RTD+K+++TSAT+ KFS YF AP+ + G+ Y V+++Y EP + + ++Q IH GDIL+FLTGQE+I+ C+ L + L +LP+Y AL + Q IF PA PG RKV+++TNIAETS+TIDGI +V+D G+VKQ +++S++GID L ISQ QA QR GRAGRT G CYRLYTE YR M PEI R NL T L + +GI D +SF F+D+P ETL + +L L +D+ +T LG+ + +FP+EP + K L S C E++TI++M+S +NVF RPK +D K KF EGD L Y +W N+ S WCY+NF+ +++ + +R Q++G++ R + V ++K++ F++N + + Y ++QQV+Y+HPSS L N ++Y+E+V T K YMR + T+ L EF Sbjct: 546 LPIYKLKEQLIQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTTRGKIGCTQPRRVAAMSVAKRVSEEYGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLGQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRTDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEVLYTKEPETDYLDASLITVMQ-IHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQPEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVFSCGKATV-RVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTIDPRWLVEF 1157
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Cavefish
Match: dhx8 (DEAH-box helicase 8 [Source:NCBI gene;Acc:103035799]) HSP 1 Score: 528.865 bits (1361), Expect = 1.135e-172 Identity = 272/614 (44.30%), Postives = 385/614 (62.70%), Query Frame = 3 Query: 186 LPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNL--------ESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYR-AMKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEF 1991 LPI + K+ +I+ V +NQI+I+ G TGSGKTTQI QYL EAG IG TQPRR+AA+++A RV++E CLG EVGY +RF +S T IKYMTDG+LL +CL DP L +Y ++M+DEAHERT+ TDVL GL+K +RTD+K+++TSAT+ KFS YF AP+ + G+ Y V+++Y EP + + ++Q IH GDIL+FLTGQE+I+ C+ L + L +LP+Y AL + Q IF PA PG RKV+++TNIAETS+TIDGI +V+D G+VKQ +++S++GID L ISQ QA QR GRAGRT G CYRLYTE YR M PEI R NL T L + +GI D +SF F+D+P ETL + +L L +D+ +T LG+ + +FP+EP + K L S C E++TI++M+S +NVF RPK +D K KF EGD L Y +W N+ S WCY+NF+ +++ + +R Q++G++ R + V ++K++ F++N + + Y ++QQV+Y+HPSS L N ++Y+E+V T K YMR + T+ L EF Sbjct: 585 LPIYKLKEQLIQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTTRGKIGCTQPRRVAAMSVAKRVSEEYGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLGQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRTDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEVLYTKEPETDYLDASLITVMQ-IHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQPEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVFSCGKATV-RVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTIDPRWLVEF 1196
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Cavefish
Match: dhx16 (DEAH-box helicase 16 [Source:NCBI gene;Acc:103040087]) HSP 1 Score: 499.59 bits (1285), Expect = 8.133e-164 Identity = 272/632 (43.04%), Postives = 389/632 (61.55%), Query Frame = 3 Query: 135 LSFLTQQLQGIKVSDKELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAG-INNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNLES--------IQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYRAMKQETT-PEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERN-VFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTE 1988 LS +Q Q I+ + LP+ Y+ ++ +R++QI++I G TGSGKTTQIPQYL E G IG TQPRR+AA+++++RVAQE+ LG EVGY +RF +S T +KYMTDG+LL + L +P L Y V++IDEAHERT+ TD+L GLIK +A R DLKVL+ SAT+ E+FS +F APV G+ + V I Y P + + +++Q IH GDIL+FLTGQE+IE CC+NL+ I L VLP+Y L D Q IF P PG RKV+V+TNIAETS+TIDGI +VID G+ KQ +++R+G++SL S+ A QR GRAGR G C+RLYT ++ +ETT PEI R NL L + +GI D + F F+D P HETL L +L L ++ ++T+LG+ + + PV+P + K + AS +Y C EV+TI AM+S N +F RPK V +D ++ F GD + LN Y W E+ S QWC++NF+ F++M++ VR QL GL++R ++ + I+KS+ ++ + R SKG Y +QQ +Y+HP+S L ++Y+E+V T K +MR ++ + + L E Sbjct: 361 LSQAEKQKQSIQEVRRSLPVFPYRQDLLNAIRDHQILVIEGETGSGKTTQIPQYLMEDGYTKGGMKIGCTQPRRVAAMSVSARVAQEVGVKLGNEVGYSIRFEDCTSERTVLKYMTDGMLLREFLTEPDLASYSVIIIDEAHERTLHTDILFGLIKDIARFRPDLKVLVASATLDTERFSCFFDDAPVFRIPGRRFPVDIFYTKAPEADYLDACVVSVLQ-IHVTQPPGDILVFLTGQEEIESCCENLQERCRRLGSKISELLVLPIYANLPSDMQAKIFNPTPPGARKVVVATNIAETSLTIDGIIYVIDPGFCKQKSYNARTGMESLIVTPCSRASANQRAGRAGRVAAGKCFRLYTAWAFKHEMEETTVPEIQRTNLGNVVLLLKSLGINDLIHFDFMDPPPHETLVLALEQLYALGALNHLGELTKLGRRMAELPVDPMLSKMILASEQYKCSEEVLTIAAMLSVNNSIFYRPKDKVVHADNARMNFIVPGGDHLVLLNVYTQWVESGFSTQWCFENFIQFRSMKRARDVREQLEGLMERIEVEVCSANGDST-PIRKSITAGYFYHTA-RLSKGGYKTVKHQQTVYVHPNSSLFEEQPRWLIYHELVFTTKEFMRQVIEIDSAWLLE 989
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Cavefish
Match: dhx16 (DEAH-box helicase 16 [Source:NCBI gene;Acc:103040087]) HSP 1 Score: 498.819 bits (1283), Expect = 3.957e-163 Identity = 272/632 (43.04%), Postives = 389/632 (61.55%), Query Frame = 3 Query: 135 LSFLTQQLQGIKVSDKELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAG-INNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNLES--------IQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYRAMKQETT-PEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERN-VFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTE 1988 LS +Q Q I+ + LP+ Y+ ++ +R++QI++I G TGSGKTTQIPQYL E G IG TQPRR+AA+++++RVAQE+ LG EVGY +RF +S T +KYMTDG+LL + L +P L Y V++IDEAHERT+ TD+L GLIK +A R DLKVL+ SAT+ E+FS +F APV G+ + V I Y P + + +++Q IH GDIL+FLTGQE+IE CC+NL+ I L VLP+Y L D Q IF P PG RKV+V+TNIAETS+TIDGI +VID G+ KQ +++R+G++SL S+ A QR GRAGR G C+RLYT ++ +ETT PEI R NL L + +GI D + F F+D P HETL L +L L ++ ++T+LG+ + + PV+P + K + AS +Y C EV+TI AM+S N +F RPK V +D ++ F GD + LN Y W E+ S QWC++NF+ F++M++ VR QL GL++R ++ + I+KS+ ++ + R SKG Y +QQ +Y+HP+S L ++Y+E+V T K +MR ++ + + L E Sbjct: 394 LSQAEKQKQSIQEVRRSLPVFPYRQDLLNAIRDHQILVIEGETGSGKTTQIPQYLMEDGYTKGGMKIGCTQPRRVAAMSVSARVAQEVGVKLGNEVGYSIRFEDCTSERTVLKYMTDGMLLREFLTEPDLASYSVIIIDEAHERTLHTDILFGLIKDIARFRPDLKVLVASATLDTERFSCFFDDAPVFRIPGRRFPVDIFYTKAPEADYLDACVVSVLQ-IHVTQPPGDILVFLTGQEEIESCCENLQERCRRLGSKISELLVLPIYANLPSDMQAKIFNPTPPGARKVVVATNIAETSLTIDGIIYVIDPGFCKQKSYNARTGMESLIVTPCSRASANQRAGRAGRVAAGKCFRLYTAWAFKHEMEETTVPEIQRTNLGNVVLLLKSLGINDLIHFDFMDPPPHETLVLALEQLYALGALNHLGELTKLGRRMAELPVDPMLSKMILASEQYKCSEEVLTIAAMLSVNNSIFYRPKDKVVHADNARMNFIVPGGDHLVLLNVYTQWVESGFSTQWCFENFIQFRSMKRARDVREQLEGLMERIEVEVCSANGDST-PIRKSITAGYFYHTA-RLSKGGYKTVKHQQTVYVHPNSSLFEEQPRWLIYHELVFTTKEFMRQVIEIDSAWLLE 1022
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Cavefish
Match: dhx16 (DEAH-box helicase 16 [Source:NCBI gene;Acc:103040087]) HSP 1 Score: 496.123 bits (1276), Expect = 1.974e-162 Identity = 270/622 (43.41%), Postives = 384/622 (61.74%), Query Frame = 3 Query: 135 LSFLTQQLQGIKVSDKELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAG-INNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNLES--------IQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYRAMKQETT-PEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERN-VFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGI 1958 LS +Q Q I+ + LP+ Y+ ++ +R++QI++I G TGSGKTTQIPQYL E G IG TQPRR+AA+++++RVAQE+ LG EVGY +RF +S T +KYMTDG+LL + L +P L Y V++IDEAHERT+ TD+L GLIK +A R DLKVL+ SAT+ E+FS +F APV G+ + V I Y P + + +++Q IH GDIL+FLTGQE+IE CC+NL+ I L VLP+Y L D Q IF P PG RKV+V+TNIAETS+TIDGI +VID G+ KQ +++R+G++SL S+ A QR GRAGR G C+RLYT ++ +ETT PEI R NL L + +GI D + F F+D P HETL L +L L ++ ++T+LG+ + + PV+P + K + AS +Y C EV+TI AM+S N +F RPK V +D ++ F GD + LN Y W E+ S QWC++NF+ F++M++ VR QL GL++R ++ + I+KS+ ++ + R SKG Y +QQ +Y+HP+S L ++Y+E+V T K +MR + Sbjct: 394 LSQAEKQKQSIQEVRRSLPVFPYRQDLLNAIRDHQILVIEGETGSGKTTQIPQYLMEDGYTKGGMKIGCTQPRRVAAMSVSARVAQEVGVKLGNEVGYSIRFEDCTSERTVLKYMTDGMLLREFLTEPDLASYSVIIIDEAHERTLHTDILFGLIKDIARFRPDLKVLVASATLDTERFSCFFDDAPVFRIPGRRFPVDIFYTKAPEADYLDACVVSVLQ-IHVTQPPGDILVFLTGQEEIESCCENLQERCRRLGSKISELLVLPIYANLPSDMQAKIFNPTPPGARKVVVATNIAETSLTIDGIIYVIDPGFCKQKSYNARTGMESLIVTPCSRASANQRAGRAGRVAAGKCFRLYTAWAFKHEMEETTVPEIQRTNLGNVVLLLKSLGINDLIHFDFMDPPPHETLVLALEQLYALGALNHLGELTKLGRRMAELPVDPMLSKMILASEQYKCSEEVLTIAAMLSVNNSIFYRPKDKVVHADNARMNFIVPGGDHLVLLNVYTQWVESGFSTQWCFENFIQFRSMKRARDVREQLEGLMERIEVEVCSANGDST-PIRKSITAGYFYHTA-RLSKGGYKTVKHQQTVYVHPNSSLFEEQPRWLIYHELVFTTKEFMRQV 1012
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Sea Lamprey
Match: dhx8 (DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Source:ZFIN;Acc:ZDB-GENE-050809-39]) HSP 1 Score: 530.791 bits (1366), Expect = 9.297e-180 Identity = 276/614 (44.95%), Postives = 386/614 (62.87%), Query Frame = 3 Query: 186 LPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNL--------ESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYR-AMKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEF 1991 LPI + K+ +++ V +NQI+I+ G TGSGKTTQI QYL EAG IG TQPRR+AA+++A RV++E CLG EVGY +RF +S TKIKYMTDG+LL +CL D +L +Y V+M+DEAHERT+ TDVL GL+K RR D+K+++TSAT+ KFS YF AP+ + G+ Y V+I+Y EP + + ++Q IH GDILLFLTGQE+I+ C+ L + L +LP+Y AL + Q IF PA PG RKV+++TNIAETS+TIDGI +V+D G+VKQ +++S++GID L ISQ QA QR GRAGRT G YRLYTE YR M PEI R NL T L + +GI D +SF F+D+P ETL + +L L +D+ +T LG+ + +FP+EP + K L S C E++TI++M+S +NVF RPK +D K KF +EGD L Y +W N+ S WCY+NFV +T+ + VR Q++G++ R + V ++K+++ F++N + + Y ++QQV+Y+HPSS L N ++Y+E+V T K YMR + T+ L EF Sbjct: 102 LPIYKLKEQLVQAVNDNQILIVIGETGSGKTTQITQYLAEAGYTTRGKIGCTQPRRVAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETKIKYMTDGMLLRECLIDSELMQYSVVMLDEAHERTIHTDVLFGLLKKTIKRRLDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLDASLITVMQ-IHLTEPPGDILLFLTGQEEIDTACEILYERMKSLGPEVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKTYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYQLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFNQAEGDHLTLLAVYNSWKNNKFSNAWCYENFVQARTLRRAQDVRKQMLGIMDRHKLDVVSCAKATV-RVQKAVLSGFFRNAAKKDPQEGYRTLVDQQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTIDPKWLVEF 713
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Sea Lamprey
Match: dhx34 (DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Source:ZFIN;Acc:ZDB-GENE-061207-30]) HSP 1 Score: 320.087 bits (819), Expect = 4.555e-96 Identity = 186/545 (34.13%), Postives = 304/545 (55.78%), Query Frame = 3 Query: 153 QLQGIKVSDKELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIYEPMWSWS-------------LYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNLESIQSLT----VLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYRAMKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRK-----SKQWCYDNFVNFKTMEQIDLVRTQLMGLV 1718 +L ++ + LPI +Y+D +++ VR +Q+V++ G TG GK+TQ+PQYL AG++ + TQPRRIA +++A RV+ E G ++GY++RF + +TK+ ++T+G+LL Q + + Y VL++DE HER + D+LLG+++ L R DL++++ SATI + FS Y APV+ G++Y +Q+IY P+ L + +I K + E+GD+L+FL+G DI + +S T VL L+ L + Q +F A G RK IVSTNIAETS+TIDG+RF++D G VK+ +D ++ + L IS+ A QRKGRAGRT G C+RLY E Y A++ PE+ R L L++ +G+ DP F F++ P +L + LQ+ +DE +++T +G+ + P++ GK L + V+TI A MS ++ F R + +++ S GD LN + W + + S++WC + + + + +I ++ Q L+ Sbjct: 94 RLAKLRRDQRNLPIHEYRDQLVELVRAHQVVVVAGDTGCGKSTQVPQYLLSAGMSR---VACTQPRRIACMSLAKRVSYESLGEHGSQIGYQIRFETSKTAATKVLFLTEGLLLRQMQTEGFMSRYDVLILDEVHERHLHCDLLLGVLRELLPLRDDLRLVLMSATINIQLFSRYLGDAPVLQVPGRLYPIQVIYRPVPEEEKTGKSERIDPRPYLRIMQSIDHK-YPADERGDLLVFLSGMADIARVAEAAQSYAVETKRWIVLQLHSTLSAEQQDKVFDLAPEGVRKCIVSTNIAETSVTIDGVRFIVDSGKVKEMSYDPKAKMQRLQEFWISRASAEQRKGRAGRTGPGVCFRLYAESEYDALEPYAVPEVQRVPLDSVVLQMKSMGLGDPRLFGFLEPPPASSLETSMQFLQEQGALDEQEELTPIGRVLATLPLDVLTGKMLLVGCVLGAVEPVLTIAAAMSVQSPFHRNAHTNPDCSRARRSLESDHGDPLTLLNVFNEWVQVKSGGQVPSRKWCKRHGLEEQRLYEIANLQRQFKELL 634
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Sea Lamprey
Match: zgc:158828 (DEAH-box helicase 35 [Source:HGNC Symbol;Acc:HGNC:15861]) HSP 1 Score: 292.738 bits (748), Expect = 4.282e-89 Identity = 189/544 (34.74%), Postives = 295/544 (54.23%), Query Frame = 3 Query: 165 IKVSDKELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINND-KTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKS-SNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQII-----YEPMWSWSLYFITNI--VQKIHNGIEKGDILLFLTGQEDIEECCQNL-ESIQS------------LTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYRAMKQETTPEIYRRNLYGTYLKIAGIGIDP-MSFKFIDSPEHETLRKCLSELQDL-DLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKR 1724 I+ + LPI ++++++ V + V+I G TG GK+TQIPQYL EAG + + +TQPRR+AA +A+RVA+E + LG EVGY +RF+ S +T+IK++TDG+L+ + + DP L +Y L++ R DT S V +TS+TI FS F ++ D ++ V Y M+ Y T + + KIHN GDIL FLTGQE++E + E +++ + LP+Y L + Q +F+ RKV+V+TN+AETS+T+ GI FV+DCG+VK +D R +D+L S+ A QR GRAGR+ G CYRLY E + + + T PE+ R ++ L++ +GID + F F+ P E++ + + L L + + LG + +FP+ P K L S + C E+ITI AMM +NVF+ P +K+ ++KF EGD LN ++A+ ++ KS WC +F+N+K + + ++ QL L++R Sbjct: 45 IQQQRQRLPIFMHRNHVLYLVEKYRTVVIVGETGCGKSTQIPQYLAEAGWTAEGHVVAITQPRRVAATTVAARVAEERGALLGHEVGYCIRFDDCSDPQATRIKFLTDGMLVREMMADPLLKKYSPLLL-----RFGDTTAPY---PTACSSFNRSLVEVTSSTIP-SSFSRAFECQCCLA-DYILWRVGQCTNARSYILMYPVPDYVKTTVETIMKIHNDAADGDILAFLTGQEEVENVVSAVVEEVRAAAARSKGSLHRHVRALPMYAGLPYVDQMKVFERVGRNCRKVVVATNVAETSVTVPGIAFVVDCGFVKLRTYDPRRAVDALLVTPASRASAQQRAGRAGRSRPGKCYRLYPESEFAKLPEATEPEMRRSDMAPVILQLKALGIDNVLRFSFLSPPPAESMVQAVELLYALGGAWRDASSSSPLGVRMAEFPMGPMYAKMLLESGTFGCSKEIITIAAMMQIQNVFLSPPNQKIKAARQQRKFAVEEGDHMTMLNVFEAFVKHNKSSAWCQQHFLNYKGLVRAGALQDQLRKLLRR 578
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Sea Lamprey
Match: dhx33 (DEAH (Asp-Glu-Ala-His) box polypeptide 33 [Source:NCBI gene;Acc:796505]) HSP 1 Score: 265.003 bits (676), Expect = 2.029e-81 Identity = 156/402 (38.81%), Postives = 230/402 (57.21%), Query Frame = 3 Query: 162 GIKVSDKELPIEQYKDYIIKTVRN-NQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEV-GYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTD-----LKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIE---ECCQNLE-----SIQSLTVLPLYGALDFDAQQDIFKPAEP-GKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYRAMKQETTPEIYRR-NLYGTYLKIAGIGI-DPMSFKFIDSP 1307 G++V + LPI + + + ++ + ++IFG T G TTQ+ + E + QP A+ + SR R G +V GY VRF S ST+++++TDG+LL + L DP L +++DEAHER++ TD L G++K +R + LKV++ SAT+ ++F +YF+GAPV+ +G+ + +QI Y EP + + I Q + IL FLTGQE+IE C++L S+ + V+PLY AL QQ +F A P G RKVI++TNIAETSITI G+R VIDCG VK +F +G++ L ++SQ QA QR GR+GR G C RLYTE ++++ + TTPE+ R NL L + +GI D SF F+D P Sbjct: 33 GLEVQRRGLPIYAVRAELTRRLQELHTAIVIFGITAQGSTTQVKSWTGEQDCPPGGEVAYMQPSHTTAVCVPSR-RDFYRQNRGRDVVGYTVRFEDVRSASTRVRFVTDGMLLREALGDPLLLATSAVVLDEAHERSLHTDTLFGVVKGAQRQRWEQKLRPLKVIVMSATMDVDRFVSYFNGAPVLYVEGRQHPIQIFYTREPHSDFLHATLITIFQTHQEQEAEHHILAFLTGQEEIEAMGRACRDLSRQLPPSVPRMCVVPLYAALPHAQQQRVFARAPPKGTRKVILATNIAETSITIPGVRTVIDCGLVKAKMFSPGTGMEVLALQKVSQAQAWQRAGRSGREGPGCCLRLYTEMHFQSLAENTTPELQSRCNLTSVLLHLLALGISDVASFDFMDKP 433
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Sea Lamprey
Match: dhx30 (DEAH (Asp-Glu-Ala-His) box helicase 30 [Source:ZFIN;Acc:ZDB-GENE-130530-833]) HSP 1 Score: 235.728 bits (600), Expect = 5.336e-66 Identity = 166/530 (31.32%), Postives = 272/530 (51.32%), Query Frame = 3 Query: 165 IKVSDKELPIEQYKDYIIKTVR--NNQIVIIFGSTGSGKTTQIPQYLFE-----AGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRF-NKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDV---------QII--YEP-----MWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNLES-----IQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYRAMKQETTPEIYRRNLYGTYL--KIAGIGIDPMSF--KFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSE---NRKSKQWC 1646 + + LPI Y+D I+ + + +++I+ G TG GKTT+IPQ + E AG + VTQPRRI+A+++ RV QE+ L +GY+VR + + + + T GILL + +P L +++DE HER V TD LL L++ + R L++L+ SAT ++ + YF GA V+ GK+Y V Q++ + P S L F+T +V+ I + G +L FL G ++I L + +LP++ +L QQ IF+ G RKV+++TNIAET+ITID I V+D G K +D R+ + L V +S+ +QR+GRAGR G+ Y L++EE + AM + TPEI R L L K+ I F + +D P + + +S LQ++ ++ + +T LG + VEP++ KAL ++ + C+ V+ I++ +S ++ A + + + D ++NA + W +R +Q C Sbjct: 375 VTPGEDPLPILDYRDEILAALEAEDRRVLIVAGETGCGKTTKIPQLILESMVSRAGNGAHCNVVVTQPRRISAVSVCQRVRQELGPHLRRNIGYQVRMESSPPTPGGAVLFCTVGILLRKLQSNPDLLGVSHVLLDEVHERDVGTDFLLVLLRDVLRRNPRLRLLLASATPDTQRLAQYFGGATVLRVPGKLYPVTPYHLRNVCQLMQRHPPSKDSDDPSPDLDFVTEVVEFICSRGTPGGVLCFLPGWQEIRGVMDRLSQRLNNRLDKHLILPVHSSLSVVDQQAIFQRPPEGVRKVVLATNIAETAITIDDIVHVVDTGCHKLQQYDMRTQVSCLDTVWVSKTNVVQRRGRAGRCQPGFSYHLFSEEQFAAMPEFETPEILRTPLESLVLQVKLHTPHIPAAQFLDQALDRPNKYAVEEAVSILQEIGVLMMDESLTPLGARLAHMAVEPRLAKALVLATLFRCLYPVLVIISSLSRDPFQSGLQQRAAVNKARRLLAGETRSDHLAFVNALEEWRHAYGDRADEQHC 904
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Yeast
Match: PRP22 (DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase; associates with lariat intermediates before the second catalytic step of splicing; mediates ATP-dependent mRNA release from the spliceosome and unwinds RNA duplexes; required for proofreading the exon ligation reaction [Source:SGD;Acc:S000000815]) HSP 1 Score: 480.715 bits (1236), Expect = 4.331e-156 Identity = 262/647 (40.49%), Postives = 387/647 (59.81%), Query Frame = 3 Query: 123 MSDTLSFLTQQLQGIKVSDKELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIYE--PMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNL--------ESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEET-YRAMKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVK----RKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEFPKESKKIG 2015 M++++S+ + I + LP+ + +I+ VR+NQ ++I G TGSGKTTQI QYL E G +N IG TQPRR+AA+++A RVA+E+ +G +VGY +RF + T+IKYMTDG+L + L DP++ +Y V+M+DEAHERTV TDVL L+K A +R +LKV++TSAT+ KFS YF P+I+ GK + V+++Y P + + + V IH GDIL+FLTGQE+I+ CC+ L +SI L +LP+Y AL + Q IF+P G RKV+ +TNIAETSITIDGI +V+D G+ K N++++R+GI+ L ISQ QA QRKGRAGRT G CYRLYTE Y M + T PEI R+NL T L + +GI D + F F+D P + L+EL L +D+ K+T LGK + FP++P + ++L +S C E++TI++M+S +NVF RPK +++D K KF GD LN Y W + S+Q+C NF++F+ +++ V++Q+ + K + + D DL I+K+ + F+ N R S+ Y + +HPSS L ++Y+ +V T + YM + ++ L E K G Sbjct: 462 MNESISYGKRTSLPISAQRQTLPVYAMRSELIQAVRDNQFLVIVGETGSGKTTQITQYLDEEGFSNYGMIGCTQPRRVAAVSVAKRVAEEVGCKVGHDVGYTIRFEDVTGPDTRIKYMTDGMLQREALLDPEMSKYSVIMLDEAHERTVATDVLFALLKKAAIKRPELKVIVTSATLNSAKFSEYFLNCPIINIPGKTFPVEVLYSQTPQMDY-IEAALDCVIDIHINEGPGDILVFLTGQEEIDSCCEILYDRVKTLGDSIGELLILPVYSALPSEIQSKIFEPTPKGSRKVVFATNIAETSITIDGIYYVVDPGFAKINIYNARAGIEQLIVSPISQAQANQRKGRAGRTGPGKCYRLYTESAFYNEMLENTVPEIQRQNLSHTILMLKAMGINDLLKFDFMDPPPKNLMLNALTELYHLQSLDDEGKLTNLGKEMSLFPMDPTLSRSLLSSVDNQCSDEIVTIISMLSVQNVFYRPKDRQLEADSKKAKFHHPYGDHLTLLNVYTRWQQANYSEQYCKTNFLHFRHLKRARDVKSQISMIFKKIGLKLISCHSDPDL-----IRKTFVSGFFMNAAKRDSQVGYKTINGGTEVGIHPSSSLYGKEYEYVMYHSIVLTSREYMSQVTSIEPQWLLEVAPHFYKAG 1102
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Yeast
Match: PRP43 (RNA helicase in the DEAH-box family; functions in both RNA polymerase I and polymerase II transcript metabolism; catalyzes removal of U2, U5, and U6 snRNPs from the postsplicing lariat-intron ribonucleoprotein complex; required for efficient biogenesis of both small- and large-subunit rRNAs; acts with Sqs1p to promote 20S to 18S rRNA processing catalyzed by endonuclease Nob1p [Source:SGD;Acc:S000003088]) HSP 1 Score: 465.307 bits (1196), Expect = 2.387e-154 Identity = 259/634 (40.85%), Postives = 389/634 (61.36%), Query Frame = 3 Query: 180 KELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQY-LFEAGINNDKT-IGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIYEPMWSWSLYFITNI--VQKIHNGIEKGDILLFLTGQEDIEECCQNL----------ESIQSLTVLPLYGALDFDAQQDIFKPA------EPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETY-RAMKQETTPEIYRRNLYGTYLKIAGIGIDPM-SFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSK----QWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLN---LVDSIKKSLIPSFYKNICFRKS--KGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTE 1988 +ELP+ +D +K +NNQI++ G TGSGKTTQIPQ+ LF+ + + T + TQPRR+AA+++A RVA+EM LG EVGY +RF K+SN T +KYMTDG+LL + +ED L Y +++DEAHERT+ TD+L+GL+K + RR DLK++I SAT+ EKF YF+ AP+++ G+ Y V++ Y P + Y + I V +IH E GDILLFLTG+++IE+ + + E L+V PLYG+L QQ IF+PA PG RKV++STNIAETS+TIDGI +V+D G+ KQ +++ R ++SL IS+ A QR GRAGRT G C+RLYTEE + + + +++ PEI R NL T L++ +GID + F F+D P ET+ + L EL L +D+ +T LG+ FP++P + L S ++ C E++TI+AM+S NVFIRP K ++D +K F +GD LN Y A+ + + +WC D+++N++++ D +R+QL L+ R +D D+I+K+L F+ + ++S KG YI + Q + +HPS+ L + + ++Y E V T K Y+R + ++ L E Sbjct: 91 RELPVHAQRDEFLKLYQNNQIMVFVGETGSGKTTQIPQFVLFDEMPHLENTQVACTQPRRVAAMSVAQRVAEEMDVKLGEEVGYSIRFENKTSNKTILKYMTDGMLLREAMEDHDLSRYSCIILDEAHERTLATDILMGLLKQVVKRRPDLKIIIMSATLDAEKFQRYFNDAPLLAVPGRTYPVELYYTPEFQRD-YLDSAIRTVLQIHATEEAGDILLFLTGEDEIEDAVRKISLEGDQLVREEGCGPLSVYPLYGSLPPHQQQRIFEPAPESHNGRPG-RKVVISTNIAETSLTIDGIVYVVDPGFSKQKVYNPRIRVESLLVSPISKASAQQRAGRAGRTRPGKCFRLYTEEAFQKELIEQSYPEILRSNLSSTVLELKKLGIDDLVHFDFMDPPAPETMMRALEELNYLACLDDEGNLTPLGRLASQFPLDPMLAVMLIGSFEFQCSQEILTIVAMLSVPNVFIRPTKDKKRADDAKNIFAHPDGDHITLLNVYHAFKSDEAYEYGIHKWCRDHYLNYRSLSAADNIRSQLERLMNRYNLELNTTDYESPKYFDNIRKALASGFFMQVAKKRSGAKG-YITVKDNQDVLIHPSTVLGHD-AEWVIYNEFVLTSKNYIRTVTSVRPEWLIE 720
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Yeast
Match: PRP16 (DEAH-box RNA helicase involved in second catalytic step of splicing and in exon ligation; exhibits ATP-dependent RNA unwinding activity; mediates the release of Yju2p and Cwc25p in the second step; in the absence of ATP, stabilizes the binding of Cwc25p to the spliceosome in the first catalytic step; missense mutation in human ortholog DHX38 associated with early-onset retinitis pigmentosa [Source:SGD;Acc:S000001794]) HSP 1 Score: 437.187 bits (1123), Expect = 3.228e-140 Identity = 260/654 (39.76%), Postives = 383/654 (58.56%), Query Frame = 3 Query: 129 DTLSFLTQQLQGIKVSDKELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINND--KTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNK-KSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIH--NGIEKGDILLFLTGQEDIEEC-----------------CQNLESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYRA-MKQETTPEIYRRNLYGTYLKIAGIGI-DPMS-FKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVK-RKFP---NYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCL--MNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEF 1991 D + T IK + ++LP+ + + ++ +R NQ+V+I G TGSGKTTQ+ QYL+E G ND K+I VTQPRR+AAI++A RVA EM+ LG EVGY +RF S TK+K++TDGILL + L D L +Y ++IDEAHER+++TD+LLG KIL +RR DLK++ITSAT+ +KFS +F AP + G+ + VQ IY P+ + ++ V KIH N GDIL+F+TGQEDIE N E I + +LP+Y AL D Q IF+ KRK+I++TNIAETS+TI GIR+VIDCGY K +++ + G+DSL IS+ A QR GRAGRT G YRLYTE+T++ M +T PEI R NL T L + + + D +S F FID P +T L EL + ID ++T LG + FP++P + K L + + C E++TI++M+S VF RPK+ ++D ++ KFF ++ D LN ++ W N S WC +FV +K++ + +R QL+ ++K +K P + +D D+ IKK + F Y++ + +HP+S L + P ++Y+E++ T K Y+ + ++ L E+ Sbjct: 331 DDTALFTPSKDDIKHTKEQLPVFRCRSQLLSLIRENQVVVIIGETGSGKTTQLAQYLYEEGYANDRGKSIVVTQPRRVAAISVAKRVAMEMQVPLGKEVGYSIRFEDVTDSECTKLKFVTDGILLRETLLDDTLDKYSCVIIDEAHERSLNTDILLGFFKILLARRRDLKLIITSATMNAKKFSAFFGNAPQFTIPGRTFPVQTIYTSNPVQDYVEAAVSQAV-KIHLANDCSSGDILIFMTGQEDIETTFDTLQEKFLQVYSKKFGTANFEEINDIEILPIYSALPADLQFKIFQDLHGTKRKIIIATNIAETSLTIKGIRYVIDCGYSKLKVYNPKIGLDSLVITPISKANADQRSGRAGRTAPGTAYRLYTEDTFKEDMYLQTIPEIQRTNLSNTLLLLKSLDVTDELSKFPFIDKPPLQTFLSSLYELWFIGAIDTSGQLTPLGLQMAKFPLQPSLSKILLIAVRNGCSDEMLTIVSMLSVPQVFYRPKERQKEADIARNKFFIAKSDHLTLLNVFEQWRANNFSSHWCNKHFVQYKSLVRARDIRDQLLTILKSQKIPVISSGKDWDI-----IKKCICSGFAHQAAKITGLRNYVHLKTGVSVQLHPTSALHGLGDLPPYVVYHELLMTSKEYICCVTSVDPFWLMEY 978
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Yeast
Match: PRP2 (RNA-dependent DExD/H-box ATPase; required for activation of spliceosome before first transesterification step in RNA splicing; implicated in rearranging and proofreading snRNA structure in catalytic activation of spliceosome; ortholog of human protein DHX16 [Source:SGD;Acc:S000005294]) HSP 1 Score: 399.053 bits (1024), Expect = 1.340e-127 Identity = 228/547 (41.68%), Postives = 332/547 (60.69%), Query Frame = 3 Query: 165 IKVSDKELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKT--IGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSS-NSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIE-KGDILLFLTGQEDIEECCQNLESIQS--------LTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETY-RAMKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKY----FCITEVITIMAMMSER-NVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQL------MGLVKR 1724 I+ + K LP+ QYKD +++ ++ NQ++II G TGSGKTTQ+PQYL E G + I +TQPRR+AA ++A+RVA EM LG EVGY++RF K++ N T +KYMTDG+LL + L D KL +Y +MIDEAHERT+ TD+L+GL+K + +R LK+LI+SAT+ +KFS +F P+ + G+ Y V I Y +P ++ IT I Q IH GDIL+FLTGQE+IE LE I S + + P+Y L + Q IF+P RKV+++TNIAETS+TIDGIR+VID G+VK+N + +G+ L V S+ QR GRAGR G C+R++T+ +Y ++ PEI R NL T L + +G+ D + F +D P TLRK L L L ++ IT LGK + +FP EP+ K L+ ++ + + E +TI++M+ E ++FI K+ A S S+ E D +YL + W ++ S+ WC D+ + FKTM ++ +R QL +GLV++ Sbjct: 216 IQEARKLLPVHQYKDELLQEIKKNQVLIIMGETGSGKTTQLPQYLVEDGFTDQGKLQIAITQPRRVAATSVAARVADEMNVVLGKEVGYQIRFEDKTTPNKTVLKYMTDGMLLREFLTDSKLSKYSCIMIDEAHERTLATDILIGLLKDILPQRPTLKLLISSATMNAKKFSEFFDNCPIFNVPGRRYPVDIHYTLQPEANYIHAAITTIFQ-IHTTQSLPGDILVFLTGQEEIERTKTKLEEIMSKLGSRTKQMIITPIYANLPQEQQLKIFQPTPENCRKVVLATNIAETSLTIDGIRYVIDPGFVKENSYVPSTGMTQLLTVPCSRASVDQRAGRAGRVGPGKCFRIFTKWSYLHELELMPKPEITRTNLSNTVLLLLSLGVTDLIKFPLMDKPSIPTLRKSLENLYILGALNSKGTITRLGKMMCEFPCEPEFAKVLYTAATHEQCQGVLEECLTIVSMLHETPSLFIGQKRDAAASVLSE-----VESDHILYLEIFNQWRNSKFSRSWCQDHKIQFKTMLRVRNIRNQLFRCSEKVGLVEK 756
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Yeast
Match: DHR2 (Predominantly nucleolar DEAH-box ATP-dependent RNA helicase; required for 18S rRNA synthesis [Source:SGD;Acc:S000001561]) HSP 1 Score: 362.459 bits (929), Expect = 3.503e-115 Identity = 225/641 (35.10%), Postives = 348/641 (54.29%), Query Frame = 3 Query: 186 LPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDK--TIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIK-ILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNLESIQS----------LTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYRAMKQETTPEIYRRNLYGTYLKIAGIGIDP-MSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFS------SEGDQFMYLNAY--------KAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQ---------DSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCL-MNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTE 1988 LP+ Q+K I+ + +N + ++ G TGSGK+TQIPQ++ E + K +I VTQPRR+AAIN+A+RVAQE LG +VGY VRF+ ++ T++KY+TDG+LL + + + L EY V++IDEAHERTV TD++LG +K ++ R DL++++ SAT+ EKFS +F+ AP++ +G+ +DV+ Y P I +Q I+ G E GDIL FL GQE+I++ +E I + PLY AL Q +F P + KRKV+ STNIAETS+TI G++FV+D G K ++ + G+ +L V ISQ A+QR GRAGR + G +RLY E Y + +++ PEI R ++ L + G+D +++ + ++P E + L EL +L +D KIT+ G+ + P++P + L +S+ C+++VI I++ +S N+ + P S + D ++ S GD M + K+ + + WC ++ + + + VR QL KR F + D L+ I K + F KN Y + + +HPSS L MN P I+Y E V T K Y R + + S L E Sbjct: 81 LPVYQHKREIMSYIESNPVTVLIGETGSGKSTQIPQFVLEKLYDTKKHGSIAVTQPRRVAAINLATRVAQEHGCKLGEQVGYSVRFDNTTTTRTRLKYLTDGMLLRELMMNSDLREYSVIVIDEAHERTVLTDLILGFLKSLIQGPRPDLRIIVMSATLQAEKFSEFFNNAPILFVEGRKFDVKQYYLKAPTDDIVDAVIRCCIQ-INQGEELGDILCFLPGQEEIDKAVTIMEKIAKYVSDEAPVPLIVPYPLYAALPAVQQSLVFAPIKGFKRKVVFSTNIAETSVTISGVKFVVDSGLRKVKVWRHQLGLATLLTVPISQASAMQRSGRAGRESEGKSFRLYCESDYVKLPKQSEPEIARSDVTSPVLMLKRYGVDDLLNWTWFENPGKEAIVMGLQELYELGALDTRGKITKRGQQMALLPLQPHLSSVLIKASEVGCLSQVIDIVSCLSVENLLLNP--SPEERDEVNERRLSLCNAGKRYGDLIMLKELFDIYFYELGKSQDASSERNDWCKGLCISIRGFKNVIRVRDQLRVYCKRLFSSISEEDEESKKIGEDGELISKILKCFLTGFIKNTAIGMPDRSYRTVSTGEPISIHPSSMLFMNKSCPGIMYTEYVFTTKGYARNVSRIELSWLQE 718
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Nematostella
Match: EDO32531 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SUS3]) HSP 1 Score: 445.662 bits (1145), Expect = 3.484e-147 Identity = 244/620 (39.35%), Postives = 362/620 (58.39%), Query Frame = 3 Query: 186 LPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTD-----LKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNLESIQ--------SLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYRAMKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFK---KITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTE 1988 LPI + +I +RN Q VII G TGSGKTTQIPQYL+EA + + I TQPRR+AAI++A RV++EM LG EVGY VRF +S T+IKYMTDG+LL + + D L Y V+++DEAHERT+ TDVL G++K R D LK+++ SAT+ +FS YF A V+ +G+ + V+++Y EP + + I+Q GDIL+FLTGQ++IE + + L V P++ AL Q +F+PA PG RKVI+STNIAETS+TI G+++VID GYVK F ++G+D L +S+ QA QR GRAGR +G CYRLYTEE + + + T PEI R NL L++ +GI D SF F+D P + + L +L L+ + E K+T LG+ + FP+EP++ K + AS C E++T++A++S ++ P+ + ++KF SSEGDQ LN Y+A+ + +K WC ++F+N + M+ + +R QL + R Q + ++++ L + N + G Y +++ + +HPSS L + ++Y E+V T K YMR + +S L E Sbjct: 58 LPIFSARKSLITEIRNRQNVIIVGETGSGKTTQIPQYLYEAKVARNSVIACTQPRRVAAISIAQRVSREMGVQLGEEVGYTVRFEDVTSTKTRIKYMTDGMLLRESIGDSLLKRYSVIILDEAHERTIHTDVLFGIVKGAQISRKDKGMLPLKIVVMSATLEAHQFSEYFGSAEVLYIEGRQHPVELMYAVEPQVDYMHAALITIMQLHQEKPLGGDILVFLTGQDEIESLSKLVSDCSLHCPPDCPQLLVCPMFAALPSSQQMQVFRPAIPGARKVILSTNIAETSVTIPGVKYVIDTGYVKAKGFHPKTGLDMLRVQPVSKAQARQRLGRAGRECSGVCYRLYTEEQFEQLAEATVPEIQRCNLSSVILQLMALGIADIASFDFMDKPSADAIDGALKQLVILEALQEINGDYKLTSLGQKMAQFPLEPRLAKVILASETLGCSEEILTVVALLSVDSITYTPQSKRDHALKVRKKFLSSEGDQITLLNIYRAYKQCGMNKSWCAEHFINTRVMKLVMDIRKQLREICIRLEIKLQSCGKDSA-TLRQCLCRGLFMNSAELQLDGTYQTLNHRETVAIHPSSSLFMSKPAYVVYNELVHTSKCYMRDVSVVSCDWLLE 676
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Nematostella
Match: EDO45861 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRP1]) HSP 1 Score: 395.201 bits (1014), Expect = 6.261e-129 Identity = 239/595 (40.17%), Postives = 342/595 (57.48%), Query Frame = 3 Query: 126 SDTLSFLTQQLQGIKVSDKELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINND-KTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKK-SSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSG----------APVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNL--------ESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYRAMKQETTPEIYRRNLYGTYLKIAGIGIDPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITE-LGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKR-KFPNYQ-DSDLNLVDSIKKSLIPSFYKNICFRKSKGIY 1835 S T F I + + LPI +++ I+ + + VII G TG GK+TQ+ +YL E+G D K IG+TQPRR+AAI +A RVA+E + G EVGY VRFN T IK+MTDGILL + + DP L Y V+MIDEAHERT+ TDVLLGL+K + +R DL+++++SAT+ E F ++F+ A V+S +G+ Y V I Y P+ ++ L IH GDIL+FLTGQE++E L + L VLP+Y L ++ Q +FK P RKVIV+TN+AE SITIDGI +V+DCG+VK + +GI+SL ISQ A QR GRAGR G YRLYTE+ +K T PE+ +R G LK GI + + F F P +++ + L L LD +D+ K+ + LG + +FP+EP I K L S ++ C E++TI AM+ +NVF+ P S+++++KF EGD LN ++A+ +++KS +WC+DNFVN+K + +R QL L++ K P D D VD + + ++ F+ N G Y Sbjct: 19 STTTVFNPNSSLSIDIQRQRLPIFKHRTNILYLLEKYETVIIVGETGCGKSTQV-KYLLESGWTADGKKIGITQPRRVAAITVAIRVAEERDTFAGQEVGYCVRFNDCFDPKLTSIKFMTDGILLREVMGDPLLSSYSVIMIDEAHERTLHTDVLLGLLKKIKKKRPDLRIIVSSATLDAEMFKDFFNTNITNDKSKDTAAVLSVEGRSYPVNIEYAISPVANY-LQSAVETAMGIHLEEGPGDILVFLTGQEEVESAVSKLIERARGMPKGSSYLKVLPMYSGLPYEEQMLVFKRPPPNTRKVIVATNVAEASITIDGIVYVVDCGFVKLRAYSPATGIESLVVTEISQASAEQRAGRAGRVRAGKAYRLYTEDALHELKPVTVPEM-QRYFIGILLKSMGID-NVLRFDFPARPPAQSMVRGLELLYALDALDDNGKLVDPLGVQMAEFPLEPMIAKMLLISGEFKCSEEILTIAAMLQIKNVFVTPSSQKAASEHARRKFSVYEGDHLTQLNVHRAFLKHKKSSRWCHDNFVNYKGLMHSVKIREQLKKLLQHFKIPIVSCDGD---VDQVCRCIVAGFFSNAARYHPSGCY 606
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Nematostella
Match: EDO32629 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SUG0]) HSP 1 Score: 363.229 bits (931), Expect = 2.176e-118 Identity = 195/469 (41.58%), Postives = 288/469 (61.41%), Query Frame = 3 Query: 468 KYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIE-KGDILLFLTGQEDIEECCQNLE--------SIQSLTVLPLYGALDFDAQQDIFKPAEPGK------RKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYRA-MKQETTPEIYRRNLYGTYLKIAGIGIDPM-SFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVD---SIKKSLIPSFYKNI 1808 +YMTDG+LL + + DP L Y V+++DEAHERT+ TD+L+GL+K +A +R DLK++I SAT+ KF +YF P+++ G+ + V+I Y EP + I ++Q IH E KGDILLFLTGQE+IEE C+ ++ I L +PLY L QQ IF+ A P + RK +V+TNIAETS+TIDG+ FVID G+ KQ +++ R ++SL IS+ A QR GRAGRT G C+RLYTE+ ++ M T PEI R NL L++ +GID + F F+D P ETL + L L L +D+ +TELG + +FP++P++ K + AS ++ C E+++I +M+S VF+RP ++ +D SK KF +GD LN Y A+ +N + QWCYDNF+ ++M+ D VR QL ++ R + +D N D +I+K+L+ F+ + Sbjct: 1 RYMTDGMLLREAMTDPLLDRYAVILLDEAHERTLATDILMGLLKEVAKQRDDLKIIIMSATLDAGKFQDYFDHCPLMTIPGRTHPVEIFYTPEPERDYLEAAIRTVIQ-IHMVEEVKGDILLFLTGQEEIEEACKRIKKEVDNLGSEIGELKCIPLYSTLPPTQQQRIFEAAPPDRPNGAIGRKCVVATNIAETSLTIDGVVFVIDPGFSKQKVYNPRIRVESLLVSAISRASAQQRAGRAGRTRPGKCFRLYTEKAFQEEMPPNTYPEILRSNLGTVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLGALDDNGDLTELGSMMAEFPLDPQLAKMVIASCEFNCSNEILSITSMLSVPQVFLRPNEAKKAADESKMKFAHIDGDHLTLLNVYHAYKQNHEDTQWCYDNFIQHRSMKSADNVRGQLARIMDRFNLQRRSTDFNSRDYYLNIRKALVSGFFMQV 468
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Nematostella
Match: EDO49560 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGM4]) HSP 1 Score: 363.229 bits (931), Expect = 1.161e-117 Identity = 193/484 (39.88%), Postives = 282/484 (58.26%), Query Frame = 3 Query: 594 IKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIYEPMWSWSLYFITNI--VQKIHNGIEKGDILLFLTGQEDIEECCQNL--------ESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYR-AMKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVD------SIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEF 1991 +K RR DLK+++TSAT+ KFS +F AP+ + G+ + V+I+Y + S Y + V +IH GDIL+FLTGQE+I+ C+ L + L +LP+Y AL + Q IF PA PG RK +++TNIAETS+TIDGI +V+D G+VKQN+++S+SG+D+L ISQ QA QR GRAGRT G CYRLYTE YR M PEI R NL T L + +GI D +SF F+D P ET+ + L L +D +T LG+ + +FP+EP++ K L S C E++TI++M+S +NVF RPK +D K KF EGD L Y +W N+ S WC++NFV +++ + +R Q++GL+ R L++V ++K++ F++N + + Y ++ QV+Y+HPSS L N ++Y+E+V T K YMR + T+ L EF Sbjct: 1 MKKAVQRRPDLKLIVTSATLDAVKFSTFFFEAPIFTIPGRTFPVEILYT-KEAESDYLDAALITVMQIHLTEPPGDILVFLTGQEEIDTACEILYERTKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKCVIATNIAETSLTIDGIYYVVDPGFVKQNVYNSKSGMDALVVTPISQAQAKQRSGRAGRTGPGKCYRLYTERAYRDEMLATAVPEIQRTNLASTILSLKAMGINDLLSFDFMDPPPMETMISAMEALHSLSALDNEGLLTRLGRRMAEFPLEPQLSKMLIQSVHLGCSDEILTIVSMLSVQNVFYRPKDKQALADQKKAKFHQPEGDHLTLLAVYNSWKNNKFSNAWCFENFVQARSLRRAQDIRKQMLGLMDRH-------KLDVVSCGKHTARVQKAITSGFFRNAARKDPQEGYRTVVDNQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTIDPKWLVEF 476
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Nematostella
Match: EDO35622 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKZ8]) HSP 1 Score: 301.982 bits (772), Expect = 8.135e-91 Identity = 158/333 (47.45%), Postives = 216/333 (64.86%), Query Frame = 3 Query: 186 LPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIYEP--MWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQ-------NLESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTG 1157 LPI + ++ VR+NQ+VII G TGSGKTTQ+ QY+ E G N IG TQPRR+AA+++A RV++EM LG EVGY +RF +S+ T IKYMTDGILL + L + L Y V+++DEAHER+++TDVL GL++ + SRR DLK+++TSAT+ +KF+++F P G+ + V+I + M + + +Q IH KGDIL+F+ GQEDIE C+ +E L VLP+Y L D Q IF+ A G RK +V+TNIAETS+T+DGI FVID GY K +++ + G+D+L ISQ A QR GRAGRT G Sbjct: 527 LPIFAVRQELLSIVRDNQVVIIVGETGSGKTTQLTQYMHEDGYTNYGMIGCTQPRRVAAMSVAKRVSEEMDCSLGEEVGYAIRFEDVTSDKTMIKYMTDGILLRESLRESDLDHYSVIIMDEAHERSLNTDVLFGLLRDVVSRRRDLKLIVTSATMDAQKFADFFGNVPTYKIPGRTFPVEIFFTRTVMEDYVDSAVKQALQ-IHLTPSKGDILVFMPGQEDIEVTCELISERLAEVEEAPPLAVLPIYSQLPSDLQAKIFQKAPDGVRKCVVATNIAETSLTVDGIMFVIDAGYCKLKVYNPKIGMDALQVYPISQANANQRSGRAGRTGPG 858
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Medaka
Match: dhx8 (DEAH-box helicase 8 [Source:NCBI gene;Acc:101162325]) HSP 1 Score: 526.939 bits (1356), Expect = 3.608e-172 Identity = 270/614 (43.97%), Postives = 385/614 (62.70%), Query Frame = 3 Query: 186 LPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNL--------ESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYR-AMKQETTPEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEF 1991 LPI + K+ +++ V +NQI+I+ G TGSGKTTQI QYL EAG IG TQPRR+AA+++A RV++E CLG EVGY +RF +S T IKYMTDG+LL +CL D +L +Y ++M+DEAHERT+ TDVL GL+K +RTD+K+++TSAT+ KFS YF AP+ + G+ Y V+++Y EP + + ++Q IH GDIL+FLTGQE+I+ C+ L + L +LP+Y AL + Q IF PA PG RKV+++TNIAETS+TIDGI +V+D G+VKQ +++S++GID L ISQ QA QR GRAGRT G CYRLYTE YR M PEI R NL T L + +GI D +SF F+D+P ETL + +L L +D+ +T LG+ + +FP+EP + K L S C E++TI++M+S +NVF RPK +D K KF EGD L Y +W N+ S WCY+NF+ +++ + +R Q++G++ R + V ++K++ F++N + + Y ++QQV+Y+HPSS L N ++Y+E+V T K YMR + T+ L EF Sbjct: 561 LPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTARGKIGCTQPRRVAAMSVAKRVSEEYGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDSELGQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRTDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEVLYTKEPETDYLDASLITVMQ-IHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQPEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKATV-RVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTIDPRWLVEF 1172
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Medaka
Match: dhx16 (DEAH-box helicase 16 [Source:NCBI gene;Acc:101168894]) HSP 1 Score: 493.041 bits (1268), Expect = 6.860e-161 Identity = 270/630 (42.86%), Postives = 387/630 (61.43%), Query Frame = 3 Query: 150 QQLQGIKVSDKELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAG-INNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNLES--------IQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYRAMKQETT-PEIYRRNLYGTYLKIAGIGI-DPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERN-VFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKR---KFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTE 1988 Q +Q ++ S LPI Y++ ++ + +Q+++I G TGSGKTTQIPQYL E G N IG TQPRR+AA+++A+RVA+E+ LG EVGY +RF +S T +KYMTDG+LL + L +P L Y V++IDEAHERT+ TD+L GLIK +A R DLKVL+ SAT+ E+FS++F APV G+ + V I Y P + + +++Q IH GDIL+FLTGQE+IE CC+ L+ I L VLP+Y L D Q IF P PG RKV+V+TNIAETS+TIDGI +VID G+ KQ +++R+G++SL S+ A QR GRAGR G C+RLYT ++ +ETT PEI R NL L + +GI D + F F+D P HETL L +L L ++ ++T+LG+ + + PV+P + K + AS +Y C EV+TI AM+S N +F RPK V +D ++ F GD + LN Y W E+ S QWCY+NF+ F++M + VR QL GL++R + + Q ++ I+K++ ++ + R SKG Y +QQ +Y HP+S L ++Y+E+V T K +MR ++ + + L E Sbjct: 401 QSMQEVRRS---LPIFPYREDLLAAINEHQVLVIEGETGSGKTTQIPQYLMEEGYTNGGMKIGCTQPRRVAAMSVAARVAEEIGVKLGNEVGYSIRFEDCTSERTVLKYMTDGMLLREFLTEPDLASYSVILIDEAHERTLHTDILFGLIKDIARFRPDLKVLVASATLDTERFSSFFDDAPVFRIPGRRFPVDIFYTKAPEADYLDACVVSVLQ-IHVTQPPGDILVFLTGQEEIEACCELLQERCRRLGSKIAELLVLPIYANLPSDMQAKIFTPTPPGARKVVVATNIAETSLTIDGIIYVIDPGFCKQKSYNARTGMESLIVTPCSRASANQRAGRAGRVAAGKCFRLYTAWAFKHEMEETTVPEIQRTNLGNVVLLLKSLGINDLIHFDFMDPPPHETLVLALEQLYALGALNHLGELTKLGRRMAELPVDPMLSKMILASEQYKCSEEVLTIAAMLSVNNSIFYRPKDKVVHADNARMNFVVPGGDHLVLLNVYTQWVESGFSTQWCYENFIQFRSMRRARDVRDQLEGLMERIEVEVVSCQGENV----PIRKAVTAGYFYHTA-RLSKGGYKTVKHQQTVYTHPNSSLFEEQPRWLIYHELVFTTKEFMRQVIEIESAWLLE 1021
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Medaka
Match: dhx15 (pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 [Source:NCBI gene;Acc:101166992]) HSP 1 Score: 471.085 bits (1211), Expect = 1.592e-156 Identity = 248/614 (40.39%), Postives = 378/614 (61.56%), Query Frame = 3 Query: 183 ELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQY---LFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNLE--------SIQSLTVLPLYGALDFDAQQDIFKPAEPGK------RKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYRA-MKQETTPEIYRRNLYGTYLKIAGIGIDPM-SFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVD---SIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMR 1952 +LP+ +Y++ + + NQ ++ G TGSGKTTQIPQ+ + + + + TQPRR+AA+++A RVA EM LG EVGY +RF SS T +KYMTDG+LL + + DP L YGV+++DEAHERT+ TD+L+G++K + +RTDLKV++ SAT+ KF YF P+++ G+ + V+I Y EP + I ++Q E+GD+LLFLTGQE+I+E C+ ++ + + ++PLY L QQ IF+P+ P K RKV+VSTNIAETS+TIDG+ FVID G+ KQ +++ R ++SL +S+ A QR GRAGRT G C+RLYTE+ Y+ M+ T PEI R NL L++ +GID + F F+D P ETL + L L L +++ +TELG + +FP++P++ K + AS +Y C E++TI AM+S F+RP ++ +D SK +F +GD LN Y A+ +N +S QWCYDNFVN++++ D VR QL +++R + ++ + D +I+++L+ F+ + + G Y+ + QV+ +HPS+ L + +LY E V T K Y+R Sbjct: 48 QLPVWEYRERFTEILMRNQSFVLVGETGSGKTTQIPQWCVDMVRSLQGPKRAVACTQPRRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSAKTVLKYMTDGMLLREAMNDPLLERYGVIILDEAHERTLATDILMGVLKEIVRQRTDLKVIVMSATLDAGKFQVYFDNCPLLTIPGRTHPVEIFYTPEPERDYLEAAIRTVIQLHMCEEEEGDVLLFLTGQEEIDEACKRIKREVEDLGPEVGDMKIIPLYSTLPPQQQQRIFEPSPPNKPNGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAVSKASAQQRAGRAGRTRPGKCFRLYTEKAYKTEMQDNTYPEILRSNLGTVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNFLAALNDDGDLTELGAMMAEFPLDPQLAKMVIASCEYNCSNEILTITAMLSVPQCFVRPTEAKKVADESKLRFAHIDGDHLTLLNVYHAFKQNHESTQWCYDNFVNYRSLMSADNVRQQLSRIMERFNLPRRSTEFSSRDYYINIRRALVTGFFMQVAHLERTGHYLTVKDNQVVQLHPSTVL-DHKPEWVLYNEFVLTTKNYIR 660
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Medaka
Match: dhx15 (pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 [Source:NCBI gene;Acc:101166992]) HSP 1 Score: 471.085 bits (1211), Expect = 3.275e-156 Identity = 248/614 (40.39%), Postives = 378/614 (61.56%), Query Frame = 3 Query: 183 ELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQY---LFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNLE--------SIQSLTVLPLYGALDFDAQQDIFKPAEPGK------RKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYRA-MKQETTPEIYRRNLYGTYLKIAGIGIDPM-SFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVD---SIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMR 1952 +LP+ +Y++ + + NQ ++ G TGSGKTTQIPQ+ + + + + TQPRR+AA+++A RVA EM LG EVGY +RF SS T +KYMTDG+LL + + DP L YGV+++DEAHERT+ TD+L+G++K + +RTDLKV++ SAT+ KF YF P+++ G+ + V+I Y EP + I ++Q E+GD+LLFLTGQE+I+E C+ ++ + + ++PLY L QQ IF+P+ P K RKV+VSTNIAETS+TIDG+ FVID G+ KQ +++ R ++SL +S+ A QR GRAGRT G C+RLYTE+ Y+ M+ T PEI R NL L++ +GID + F F+D P ETL + L L L +++ +TELG + +FP++P++ K + AS +Y C E++TI AM+S F+RP ++ +D SK +F +GD LN Y A+ +N +S QWCYDNFVN++++ D VR QL +++R + ++ + D +I+++L+ F+ + + G Y+ + QV+ +HPS+ L + +LY E V T K Y+R Sbjct: 75 QLPVWEYRERFTEILMRNQSFVLVGETGSGKTTQIPQWCVDMVRSLQGPKRAVACTQPRRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSAKTVLKYMTDGMLLREAMNDPLLERYGVIILDEAHERTLATDILMGVLKEIVRQRTDLKVIVMSATLDAGKFQVYFDNCPLLTIPGRTHPVEIFYTPEPERDYLEAAIRTVIQLHMCEEEEGDVLLFLTGQEEIDEACKRIKREVEDLGPEVGDMKIIPLYSTLPPQQQQRIFEPSPPNKPNGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAVSKASAQQRAGRAGRTRPGKCFRLYTEKAYKTEMQDNTYPEILRSNLGTVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNFLAALNDDGDLTELGAMMAEFPLDPQLAKMVIASCEYNCSNEILTITAMLSVPQCFVRPTEAKKVADESKLRFAHIDGDHLTLLNVYHAFKQNHESTQWCYDNFVNYRSLMSADNVRQQLSRIMERFNLPRRSTEFSSRDYYINIRRALVTGFFMQVAHLERTGHYLTVKDNQVVQLHPSTVL-DHKPEWVLYNEFVLTTKNYIR 687
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Medaka
Match: DHX15 (DEAH-box helicase 15 [Source:NCBI gene;Acc:105357480]) HSP 1 Score: 463.766 bits (1192), Expect = 5.032e-153 Identity = 248/614 (40.39%), Postives = 372/614 (60.59%), Query Frame = 3 Query: 183 ELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEA--GINNDK-TIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIY--EPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNLE--------SIQSLTVLPLYGALDFDAQQDIFKPAEPGK------RKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYRA-MKQETTPEIYRRNLYGTYLKIAGIGIDPM-SFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVD---SIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMR 1952 +LP+ +YK+ + Q ++ G TGSGKTTQIPQ+ + G+ K + TQPRR+AA+++A RVA EM LG EVGY +RF SS T +KYMTDG+LL + + DP L YGV+++DEAHERT+ TD+L+G++K + +R+DLKV++ SAT+ KF YF P+++ G+ + V+I Y EP + I ++Q E+GD LLFLTGQE+I+E C+ ++ + + ++PLY L QQ IF+P P K RKV+VSTNIAETS+TIDG+ FVID G+ KQ +++ R ++SL IS+ A QR GRAGRT G C+RLYTE+ Y+ M+ T PEI R NL L++ +GID + F F+D P ETL + L L L +++ +TELG + +FP++P++ K + AS ++ C E+++I AM+S F+RP ++ +D SK +F +GD LN Y A+ +N +S QWCYDNFVN++++ D VR QL ++ R + ++ D +I+++L F+ + + G Y+ + QV+ +HPS+ L + +LY E V T K Y+R Sbjct: 97 QLPVWEYKESFTNIITRQQSFVLVGETGSGKTTQIPQWCVDMVRGLPGPKRAVACTQPRRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSAKTILKYMTDGMLLREAMNDPLLERYGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKFQVYFDNCPLLTIPGRTHPVEIFYTPEPERDYLEAAIRTVIQIHMCEEEEGDCLLFLTGQEEIDEACKRIKREVDDLGPEVGDIKIIPLYSTLPPQQQQRIFEPPPPRKPNGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGRTRPGKCFRLYTEKAYKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLAALNDDGDLTELGSMMAEFPLDPQLAKMVIASCEFNCSNEILSITAMLSVPQCFVRPTEAKKAADESKMRFAHIDGDHLTMLNVYHAFKQNHESNQWCYDNFVNYRSLMSADNVRQQLSRIMDRFNLPRRSTEFTSRDYYINIRRALCTGFFMQVAHLERTGHYLTVKDNQVVQLHPSTVL-DHKPEWVLYNEFVLTTKNYIR 709
BLAST of ATP-dependent RNA helicase DHX8 vs. Planmine SMEST
Match: SMESG000038860.1 (SMESG000038860.1) HSP 1 Score: 1311.98 bits (3394), Expect = 0.000e+0 Identity = 636/638 (99.69%), Postives = 636/638 (99.69%), Query Frame = 3 Query: 123 MSDTLSFLTQQLQGIKVSDKELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIYEPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNLESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYRAMKQETTPEIYRRNLYGTYLKIAGIGIDPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEFPKESKKIGYNSSISL 2036 MSDTLSFLTQQLQGIKVSDKELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIYEPMWSWSLYFITNIVQ IHNGIEKGDILLFLTGQEDIEECCQNLESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYRAMKQETTPEIYRRNLYGTYLKIAGIGIDPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEFPKESKKIGYNS ISL Sbjct: 1 MSDTLSFLTQQLQGIKVSDKELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIYEPMWSWSLYFITNIVQTIHNGIEKGDILLFLTGQEDIEECCQNLESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYRAMKQETTPEIYRRNLYGTYLKIAGIGIDPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEFPKESKKIGYNSFISL 638
BLAST of ATP-dependent RNA helicase DHX8 vs. Planmine SMEST
Match: SMESG000038834.1 (SMESG000038834.1) HSP 1 Score: 634.41 bits (1635), Expect = 0.000e+0 Identity = 308/634 (48.58%), Postives = 441/634 (69.56%), Query Frame = 3 Query: 123 MSDTLSFLTQQLQGIKVSDKELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIYEPMWSWSLY--FITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNLESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYRAMKQETTPEIYRRNLYGTYLKIAGIGIDPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRK--FPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEFPKESKKI 2012 MS+ L F K + + LPI +++D I++ VRNN I++I G TGSGKTTQIPQY+ EAGIN+ K IG+TQPRRIAAINMA RVA+EM LG EVGYE+RF+K+SS TKI ++TDGILLN C+ DPKL YGV+++DEAHER+V TDV LG++K+L +R DL+V+ITSATI CE+FSNYF+ PV+ +GK++ + IY+P+ S + +V +IH E GDIL+FLTG+EDIE CC +L I++L V PLYGA+D+++QQ +FKP E +RKV+V+TNIAETSITIDGI+FVID GYVK++ F+ + L VRISQ QA QRKGR GRT++GWCYRLYT++ + + ++E PEI+ ++L +LK+ + IDP +F ++D+P L KC EL+DL +D++ KIT+LGK + FPVEP IGK L+ASSKY C + T+ AM+ E+ +F+ K+ + K +F GD F +LN Y +W N KS WC +N ++ +T+E+I +R QL+G++KR NY +L D I+K+++ F+KN+ +S Y N ++++++H SSCL + LI+Y+ Q KKP++ ++++ ++L EF +E K + Sbjct: 1 MSNYLDF--------KETTRVLPIAKFRDDILEAVRNNPIIVIVGETGSGKTTQIPQYILEAGINDGKMIGITQPRRIAAINMAKRVAEEMHCELGAEVGYEIRFDKQSSEITKINFLTDGILLNYCVIDPKLSNYGVIIVDEAHERSVSTDVTLGILKLLVEKRPDLRVIITSATIDCERFSNYFNIVPVLWIEGKVFPILEIYKPIDSIDCLTGVLKEVVNEIHLNKESGDILVFLTGEEDIENCCASLADIKNLVVFPLYGAIDYESQQKVFKPVEKNERKVVVATNIAETSITIDGIKFVIDSGYVKKSHFNLEDNVHVLETVRISQSQANQRKGRTGRTSSGWCYRLYTKDEFESFEKEIEPEIFLKDLCHIFLKLTAMDIDPFNFHYLDAPSMPVLLKCAEELRDLGCLDKYNKITDLGKIVNSFPVEPAIGKVLYASSKYGCSLNLATMFAMVLEKKLFMSSKEFRKRVFSIKSEFSDEAGDYFTFLNIYNSWKINGKSADWCLENCIDVETIEEISRIRHQLIGVLKRNDLSVNYLPPNL-CQDPIQKAILSGFFKNVSRHESSEKYFNVYRKKIVHLHTSSCLYKSKPNLIVYHSAFQIKKPFIHAALSITPNVLKEFLEEIKTV 625
BLAST of ATP-dependent RNA helicase DHX8 vs. Planmine SMEST
Match: SMESG000038834.1 (SMESG000038834.1) HSP 1 Score: 620.157 bits (1598), Expect = 0.000e+0 Identity = 303/632 (47.94%), Postives = 432/632 (68.35%), Query Frame = 3 Query: 123 MSDTLSFLTQQLQGIKVSDKELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIYEPMWSWSLYFITNIVQKIHNGIEKGDILLFLTGQEDIEECCQNLESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYRAMKQETTPEIYRRNLYGTYLKIAGIGIDPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRK--FPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTEFPKESKKI 2012 MS+ L F K + + LPI +++D I++ VRNN I++I G TGSGKTTQIPQY+ EAGIN+ K IG+TQPRRIAAINMA RVA+EM LG EVGYE+RF+K+SS TKI ++TDGILLN C+ DPKL YGV+++DEAHER+V TDV LG++K+L +R DL+V+ITSATI CE+FSNYF+ PV+ + + V + +V +IH E GDIL+FLTG+EDIE CC +L I++L V PLYGA+D+++QQ +FKP E +RKV+V+TNIAETSITIDGI+FVID GYVK++ F+ + L VRISQ QA QRKGR GRT++GWCYRLYT++ + + ++E PEI+ ++L +LK+ + IDP +F ++D+P L KC EL+DL +D++ KIT+LGK + FPVEP IGK L+ASSKY C + T+ AM+ E+ +F+ K+ + K +F GD F +LN Y +W N KS WC +N ++ +T+E+I +R QL+G++KR NY +L D I+K+++ F+KN+ +S Y N ++++++H SSCL + LI+Y+ Q KKP++ ++++ ++L EF +E K + Sbjct: 1 MSNYLDF--------KETTRVLPIAKFRDDILEAVRNNPIIVIVGETGSGKTTQIPQYILEAGINDGKMIGITQPRRIAAINMAKRVAEEMHCELGAEVGYEIRFDKQSSEITKINFLTDGILLNYCVIDPKLSNYGVIIVDEAHERSVSTDVTLGILKLLVEKRPDLRVIITSATIDCERFSNYFNIVPVLWIEDCLTGV--------------LKEVVNEIHLNKESGDILVFLTGEEDIENCCASLADIKNLVVFPLYGAIDYESQQKVFKPVEKNERKVVVATNIAETSITIDGIKFVIDSGYVKKSHFNLEDNVHVLETVRISQSQANQRKGRTGRTSSGWCYRLYTKDEFESFEKEIEPEIFLKDLCHIFLKLTAMDIDPFNFHYLDAPSMPVLLKCAEELRDLGCLDKYNKITDLGKIVNSFPVEPAIGKVLYASSKYGCSLNLATMFAMVLEKKLFMSSKEFRKRVFSIKSEFSDEAGDYFTFLNIYNSWKINGKSADWCLENCIDVETIEEISRIRHQLIGVLKRNDLSVNYLPPNL-CQDPIQKAILSGFFKNVSRHESSEKYFNVYRKKIVHLHTSSCLYKSKPNLIVYHSAFQIKKPFIHAALSITPNVLKEFLEEIKTV 609
BLAST of ATP-dependent RNA helicase DHX8 vs. Planmine SMEST
Match: SMESG000038864.1 (SMESG000038864.1) HSP 1 Score: 615.92 bits (1587), Expect = 0.000e+0 Identity = 301/609 (49.43%), Postives = 419/609 (68.80%), Query Frame = 3 Query: 168 KVSDKELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIYEPMWSWSLYFITNIVQ--KIHNGIEKGDILLFLTGQEDIEECCQNLE--SIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYRAMKQETTPEIYRRNLYGTYLKIAGIGIDPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLL 1982 K S ELPI Y+D+I++++ NQI+I+ G TG GKTTQ+P++++E +N DK IGVTQPRRI AINMA RVA E R LG E+GYE+RF+ KS STKIKYMTD ILLN+C+ D L E+ +++DEAHER++ +DVLLGL+K + S DLK++ITSATI KFS YF AP+I+ +G+ Y+V IIY P + ++ Y ++++Q +I EKGDIL+FLT QE+IE C + L+ I++L +LPL+GA+++ QQ IF P + +RKVI+STNIAETS+TID +RFVIDCGYVKQ F+ +SGID+L +VRIS+ +A QRKGR GRTN GWCYRLY E Y + PEI RRNL Y+K+ G++P F FIDSP E L + +EL++L +DE +T GK + DFPVEP+IGK L +S C+ +++ I+A+++E+N+F RPK A K+D K FF +GD F L YK+W KS +WC NF+N K +EQI LV QL+ ++KR + S ++IK+S+ ++KNIC ++++G Y ++ LY+HP S L +LY EV++ KKPYM G++ + ES L Sbjct: 21 KSSSNELPINAYRDFIVQSILENQIIIVHGETGCGKTTQMPKFIYELELNGDKVIGVTQPRRIGAINMAKRVAFETRCALGKEIGYEIRFDNKSGASTKIKYMTDAILLNKCITDRNLSEFSYIIVDEAHERSLQSDVLLGLLKDIVSHNEDLKIIITSATIDSIKFSKYFFDAPIINIEGRSYNVDIIYNP-FDFTDYVESSVIQVLQISKNPEKGDILIFLTSQEEIENCVEQLKKPGIENLILLPLFGAMEYREQQKIFDPVKDNERKVIISTNIAETSLTIDSVRFVIDCGYVKQKNFNPKSGIDNLEDVRISKSEADQRKGRVGRTNNGWCYRLYGEIDYHQFSDQVKPEILRRNLSEVYMKVLNFGLNPKQFNFIDSPTTEALLQTENELKELKFLDESGNLTADGKWMCDFPVEPRIGKILLSSIANDCVGDMVIILALLTEKNIFRRPKPQAEKADKIKANFFDEDGDPFSLLVVYKSWILCEKSPEWCRSNFLNQKALEQIYLVHQQLISILKRHDVYKEPSSTTNKEAIKRSIFAGYFKNICKKRNRGEYSRCVDSLPLYIHPGSSLFKDSPEYVLYSEVIKIKKPYMLGVLRIDESFL 628
BLAST of ATP-dependent RNA helicase DHX8 vs. Planmine SMEST
Match: SMESG000038861.1 (SMESG000038861.1) HSP 1 Score: 611.298 bits (1575), Expect = 0.000e+0 Identity = 296/605 (48.93%), Postives = 422/605 (69.75%), Query Frame = 3 Query: 180 KELPIEQYKDYIIKTVRNNQIVIIFGSTGSGKTTQIPQYLFEAGINNDKTIGVTQPRRIAAINMASRVAQEMRSCLGMEVGYEVRFNKKSSNSTKIKYMTDGILLNQCLEDPKLPEYGVLMIDEAHERTVDTDVLLGLIKILASRRTDLKVLITSATIICEKFSNYFSGAPVISFDGKMYDVQIIYEPMWSWSLYFITNI--VQKIHNGIEKGDILLFLTGQEDIEECCQNLESIQSLTVLPLYGALDFDAQQDIFKPAEPGKRKVIVSTNIAETSITIDGIRFVIDCGYVKQNLFDSRSGIDSLTNVRISQDQAIQRKGRAGRTNTGWCYRLYTEETYRAMKQETTPEIYRRNLYGTYLKIAGIGIDPMSFKFIDSPEHETLRKCLSELQDLDLIDEFKKITELGKSIQDFPVEPKIGKALFASSKYFCITEVITIMAMMSERNVFIRPKKSAVKSDYSKQKFFSSEGDQFMYLNAYKAWSENRKSKQWCYDNFVNFKTMEQIDLVRTQLMGLVKRKFPNYQDSDLNLVDSIKKSLIPSFYKNICFRKSKGIYINYLNQQVLYMHPSSCLMNTFSPLILYYEVVQTKKPYMRGIMTLSESLLTE 1988 K+LPI +KD I+ + +NQ+VII G TGSGKTTQIP+Y++E G++ + IG+TQPRRI AINMA RVA+E +G EVGYE+RF+ S ST++KYMTDGILLNQC DP L +YG++MIDEAHER + +DVLLGL+K + SR +++KV++ SAT+ +KFS YF AP+I GK++ V+IIYEP+ + Y ++ V +IH EKGDIL+FLT QE+IE+C L I+ L VLPL+ AL++D QQ +F+ + +RK I+STNIAETS+TIDG+RF+IDCGYVKQ+ F++R GID +V+IS+ QA QRKGRAGRT+ GWCYRLY E Y + PEI R+NL YLK+ G++P +F+FID P + L K EL++L +D+F +ITE GK +++FPVEP IGK + +S C+ ++I I++M++ERN+F+ ++ D ++ +FF +GD F L YK W +N KS++WC ++++ ME++ LV+ QL+ ++KR+ + + ++IKKS+ +YKN+C RK Y L++++L++HPSS L + ILY EV +TKK YM GIM L ES E Sbjct: 27 KQLPIYSFKDEILNCIMDNQVVIIHGETGSGKTTQIPKYIYELGLHGNAMIGITQPRRIGAINMAKRVAEETNCAIGKEVGYEIRFDNSSGASTRVKYMTDGILLNQCTTDPNLKDYGIIMIDEAHERALRSDVLLGLLKSIVSRSSNIKVIVASATMDTKKFSRYFYNAPIIYITGKLFPVEIIYEPLQGEN-YIDASVRKVNEIHRKPEKGDILVFLTSQEEIEKCTDLLRGIKDLLVLPLFSALEYDEQQKVFEEVKDYERKAIISTNIAETSLTIDGVRFIIDCGYVKQSNFNARLGIDIWEDVKISKAQANQRKGRAGRTSNGWCYRLYGENEYNRFSDQEKPEIQRKNLSEIYLKVVSFGLNPKTFEFIDPPSSDALLKSEKELKELKFLDKFGEITEEGKLMENFPVEPTIGKIILSSISNKCVGDMIIILSMLTERNIFLSTRRDRFSKD-TRSEFFDDDGDPFTMLKVYKEWLKNEKSEKWCKSYLIDYRKMEKVCLVQEQLILILKRQRQYSEPNPEINKEAIKKSIFAGYYKNVCQRKRGFSYSRCLDEEILFIHPSSSLFDKNPEYILYEEVRKTKKSYMHGIMKLDESYWKE 629 The following BLAST results are available for this feature:
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of ATP-dependent RNA helicase DHX8 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of ATP-dependent RNA helicase DHX8 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of ATP-dependent RNA helicase DHX8 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of ATP-dependent RNA helicase DHX8 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30020946 ID=SMED30020946|Name=ATP-dependent RNA helicase DHX8|organism=Schmidtea mediterranea sexual|type=transcript|length=2184bpback to top protein sequence of SMED30020946-orf-1 >SMED30020946-orf-1 ID=SMED30020946-orf-1|Name=SMED30020946-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=660bp MISFIYLFKIIFKLINCICLIMSDTLSFLTQQLQGIKVSDKELPIEQYKDback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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