Myosin IE
|
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30020872 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 26Note: Hover over icons to view figure legend
Homology
BLAST of Myosin IE vs. Ensembl Human
Match: MYO1E (myosin IE [Source:HGNC Symbol;Acc:HGNC:7599]) HSP 1 Score: 1147.88 bits (2968), Expect = 0.000e+0 Identity = 591/1119 (52.82%), Postives = 782/1119 (69.88%), Query Frame = 3
Query: 72 HHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRM-NKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELK-NPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPEG---FQGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTKPGNRDLRAIQAILPTLEKSGIRIKRADTKKVINQTQSFMKSNQQIDRNSTDKLPNLPQSGKAKFPSMSQMRMTPVMGVNPRQSQITDEELVKSV------------SKNSKRESNITDXXXXXXXXXXXXXXXXVNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 3377
+HWQS K+S DD+VLL KI+++SI ENLKKR+MDD I+TYIG+VLI+VNPFK++ F +KEI MYQGAA YENPPHIYA+ADNM+RNM+ID E+QCVIISGESGAGKTV+AK+IM YIS+VSGG +V+ +K+IIL+SNPLLEAFGNAKTVRNNNSSRFGKY EIQF GGEP GGKIS FLLEKSRVV++N ER+FHIFYQLIEG + + GIT+ DYY YL+ SG YKVDD DD+ EF+ T+HAM V+G+ +EQ +L IVA +LHLGN+ F E A + + L FP YLLG+ + L K+ SR+M + K ++I + N +QA RDAL+KAL++R+FD++VD IN AM + ++ NIG+LDIYGFEIF KNGFEQFCIN+VNEKLQQIFIELTLKAEQ+EYVQEG++WTP+ YFNNK+VCDLIE K NPPG+ SILDDVCAT V + D + K+ + +H++S + GF I HYAGKVSY+ +GFCERNRD L +D+IE+MQ S PFI LFPEN+ K R T T GS+I+KQANDLV L KC PHYIRCIKPNETKK RDWE RV QV YLGL+ENI VRRAGYAYRR F+KF+QRYAIL+K TWP W G+ K+G+ HL+++ +++ Q+Q+G++K+FIK PESLFLLEE RERK++ YA+VIQ +R+ A K Y+++RE A+DL NKKERR +S+NRNFIGDY+ ++E+P+L+ +GKREK++F+ V KYDRRFK + RDL+LT K +YLIGR+K+KQG KG EV+KRK++I + ++LS D+ ++ +EYDS++E FKTEF+ +L+KRY E T + L LKF + +K E + G S+++ F D+A V + + VS+ GLP N++P R+ + + ++ A +Q + RN P+ P S ++ S+ P + PRQ + + + ++ + +R++ +P +P V + +ALYAY+A DTDELS DII++++ED GWWTG++ + GL P+NYV KI
Sbjct: 9 YHWQSHNVKHSGVDDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMYQGAAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVSGGGTKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASAEQKHSLGITSMDYYYYLSLSGSYKVDDIDDRREFQETLHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKEVGNYAAVESEEFLAFPAYLLGINQDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSINKAMEKDHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQIGSHEHFNSWNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELPFIKSLFPENLQADKKGRPT-TAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPRDWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPSWQGEEKQGVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWRKFVARKKYVQMREEASDLLLNKKERRRNSINRNFIGDYIGMEEHPELQQFVGKREKIDFADTVTKYDRRFKGVKRDLLLTPKCLYLIGREKVKQGPDKGLVKEVLKRKIEIERILSVSLSTMQDDIFILH-EQEYDSLLESVFKTEFLSLLAKRYEEKTQKQLPLKFSNTLELKLKKENWGPWSAGGSRQVQF----HQGFGDLA--VLKPSNKVLQVSIGPGLPKNSRPTRRNTTQNTGYSSGTQNANYPVRAAPPPPGYHQN--------GVIRNQYVPYPHAPGSQRSNQKSLYTSMARPPL---PRQQSTSSDRVSQTPESLDFLKVPDQGAAGVRRQTTSRPPPAGGRPKPQPKPKPQVPQCKALYAYDAQDTDELSFNANDIIDIIKEDPSGWWTGRLRGKQGLFPNNYVTKI 1108
BLAST of Myosin IE vs. Ensembl Human
Match: MYO1F (myosin IF [Source:HGNC Symbol;Acc:HGNC:7600]) HSP 1 Score: 1134.01 bits (2932), Expect = 0.000e+0 Identity = 581/1114 (52.15%), Postives = 765/1114 (68.67%), Query Frame = 3
Query: 63 KNMHHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRM-NKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELK-NPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPEGFQGGSSKKITFTVATQNKTCDVAS-KVQGLLSTAMTVSVPRGLPSNTKPGNRDL---RAIQAILPTLEKSGIRIKRADTKKVINQTQSFMKSNQQIDRNSTDKLPNLPQS---GKAKFPSMSQMRMTPVMGVNPRQSQITDEELVKSVSKNSKRESNITDXXXXXXXXXXXXXXXXVNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 3377
K HWQS K S DD+VLLP+I++D+I NL+KRFMDD I+TYIG+VLI+VNPFK++ FT +EI +YQGAA YENPPHIYA+ DNM+RNM+ID E+QCVIISGESGAGKTV+AK+IM YISKVSGG +V+ +K+IIL+SNPLLEAFGNAKTVRNNNSSRFGKY EIQF RGGEP GGKIS FLLEKSRVV+QN+NERNFHI+YQL+EG ++ R+ G+ TPDYY YLNQS Y+VD TDD+S+F T+ AM+V+G+ Q +L +VA +LHLGN+ F E A + L FP YLLG++ L K+ SR+M R + ++I + N +QA RDAL+K LY+R+FD++V+ IN AM ++ +IG+LDIYGFEIF KNGFEQFCIN+VNEKLQQIFIELTLKAEQ+EYVQEG++WTP+ YFNNKVVCDLIE K +PPG+ S+LDDVCAT D + K+ + +H++S S GF I HYAGKVSY+ GFCERNRD L D+IE+MQ S F+ LFPE + K R + T GS+I+KQANDLV L +C PHYIRCIKPNETK+ RDWE +RV QV YLGL+ENI VRRAG+AYRR F KF+QRYAIL+ ETWP+W GD ++G+QHL++ ++ Q+Q+G TK+F+K+PESLFLLEE RERKF+ +A+ IQ +R+ A + Y ++RE A+++ NKKERR +S+NRNF+GDYL L+E P+LR +GKRE+V+F+ V KYDRRFK + RDLILT K +Y+IGR+K+K+G +KGQ EV+K+K+DI AL ++LS D+F ++ DS +E FKTEF+ +L KR+ E T R L L F + F VK EG+ GG ++ +TF+ D+A KV G +TVSV GLP ++KP + + + ++ + + D V + + + T + P P S G ++ P R P N + D+ + +R+ ++ + P +P R ALY Y D DELS ++IE++ ED GWW G++ + GL P NYV+KI
Sbjct: 4 KERFHWQSHNVKQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGGEKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSDTYQVDGTDDRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESVDLLAFPAYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDFLVEAINRAMQKPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKLQAAVGTHEHFNSWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQAFLRMLFPEKLDGDKKGRPS-TAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPRDWEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRWRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQKAWRRHVAVRKYEEMREEASNILLNKKERRRNSINRNFVGDYLGLEERPELRQFLGKRERVDFADSVTKYDRRFKPIKRDLILTPKCVYVIGREKVKKGPEKGQVCEVLKKKVDIQALRGVSLSTRQDDFFILQ-EDAADSFLESVFKTEFVSLLCKRFEEATRRPLPLTFSDTLQFRVKKEGWGGGGTRSVTFSRG----FGDLAVLKVGG---RTLTVSVGDGLPKSSKPTRKGMAKGKPRRSSQAPTRAAPAPPRGMDRNGVPPSARGGPLPLEIMSGGGTHRPPRGPPSTSLGASRRP-----RARPPSEHNTEFLNVPDQGMA-----GMQRKRSVGQRPVPGVGRPKPQPRTHGPRCRALYQYVGQDVDELSFNVNEVIEILMEDPSGWWKGRLHGQEGLFPGNYVEKI 1098
BLAST of Myosin IE vs. Ensembl Human
Match: MYO1F (myosin IF [Source:HGNC Symbol;Acc:HGNC:7600]) HSP 1 Score: 1134.01 bits (2932), Expect = 0.000e+0 Identity = 581/1114 (52.15%), Postives = 765/1114 (68.67%), Query Frame = 3
Query: 63 KNMHHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRM-NKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELK-NPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPEGFQGGSSKKITFTVATQNKTCDVAS-KVQGLLSTAMTVSVPRGLPSNTKPGNRDL---RAIQAILPTLEKSGIRIKRADTKKVINQTQSFMKSNQQIDRNSTDKLPNLPQS---GKAKFPSMSQMRMTPVMGVNPRQSQITDEELVKSVSKNSKRESNITDXXXXXXXXXXXXXXXXVNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 3377
K HWQS K S DD+VLLP+I++D+I NL+KRFMDD I+TYIG+VLI+VNPFK++ FT +EI +YQGAA YENPPHIYA+ DNM+RNM+ID E+QCVIISGESGAGKTV+AK+IM YISKVSGG +V+ +K+IIL+SNPLLEAFGNAKTVRNNNSSRFGKY EIQF RGGEP GGKIS FLLEKSRVV+QN+NERNFHI+YQL+EG ++ R+ G+ TPDYY YLNQS Y+VD TDD+S+F T+ AM+V+G+ Q +L +VA +LHLGN+ F E A + L FP YLLG++ L K+ SR+M R + ++I + N +QA RDAL+K LY+R+FD++V+ IN AM ++ +IG+LDIYGFEIF KNGFEQFCIN+VNEKLQQIFIELTLKAEQ+EYVQEG++WTP+ YFNNKVVCDLIE K +PPG+ S+LDDVCAT D + K+ + +H++S S GF I HYAGKVSY+ GFCERNRD L D+IE+MQ S F+ LFPE + K R + T GS+I+KQANDLV L +C PHYIRCIKPNETK+ RDWE +RV QV YLGL+ENI VRRAG+AYRR F KF+QRYAIL+ ETWP+W GD ++G+QHL++ ++ Q+Q+G TK+F+K+PESLFLLEE RERKF+ +A+ IQ +R+ A + Y ++RE A+++ NKKERR +S+NRNF+GDYL L+E P+LR +GKRE+V+F+ V KYDRRFK + RDLILT K +Y+IGR+K+K+G +KGQ EV+K+K+DI AL ++LS D+F ++ DS +E FKTEF+ +L KR+ E T R L L F + F VK EG+ GG ++ +TF+ D+A KV G +TVSV GLP ++KP + + + ++ + + D V + + + T + P P S G ++ P R P N + D+ + +R+ ++ + P +P R ALY Y D DELS ++IE++ ED GWW G++ + GL P NYV+KI
Sbjct: 4 KERFHWQSHNVKQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGGEKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSDTYQVDGTDDRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESVDLLAFPAYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDFLVEAINRAMQKPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKLQAAVGTHEHFNSWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQAFLRMLFPEKLDGDKKGRPS-TAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPRDWEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRWRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQKAWRRHVAVRKYEEMREEASNILLNKKERRRNSINRNFVGDYLGLEERPELRQFLGKRERVDFADSVTKYDRRFKPIKRDLILTPKCVYVIGREKVKKGPEKGQVCEVLKKKVDIQALRGVSLSTRQDDFFILQ-EDAADSFLESVFKTEFVSLLCKRFEEATRRPLPLTFSDTLQFRVKKEGWGGGGTRSVTFSRG----FGDLAVLKVGG---RTLTVSVGDGLPKSSKPTRKGMAKGKPRRSSQAPTRAAPAPPRGMDRNGVPPSARGGPLPLEIMSGGGTHRPPRGPPSTSLGASRRP-----RARPPSEHNTEFLNVPDQGMA-----GMQRKRSVGQRPVPGVGRPKPQPRTHGPRCRALYQYVGQDVDELSFNVNEVIEILMEDPSGWWKGRLHGQEGLFPGNYVEKI 1098
BLAST of Myosin IE vs. Ensembl Human
Match: MYO1B (myosin IB [Source:HGNC Symbol;Acc:HGNC:7596]) HSP 1 Score: 575.474 bits (1482), Expect = 0.000e+0 Identity = 303/720 (42.08%), Postives = 453/720 (62.92%), Query Frame = 3
Query: 114 DLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTP-DYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLF-----IEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRMNKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKIN--VAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSS---------------HSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRE 2204
D+VLL +++++ NLKKRF IYTYIG+V+I+VNP++ L I++ +++ Y+ YE PHI+A++D +R++ + QC++I+GESGAGKT ++K +M Y++ V G V Q+KE +L+SNP+LEAFGNAKTVRN+NSSRFGKY++I+FD G+P+GG IS +LLEKSRVV Q + ERNFH+FYQL+ G +++ + Y+YL+ KV+ DD + F+ +AM+++G E S+L++VAAVL LGN+ F + G +++ KDK L+ C L G+++S L + R + K++ + N QA+ ARDAL+K LYSR+F ++V++IN + + +G+LDIYGFEIF N FEQF INY NEKLQQIFIELTLK EQ+EY++E ++WT ++YFNN ++CDLIE N G+ ++LD+ C VTD F+ K++ H+ S HS F I HYAGKV Y+ EGF ++N D L D+ + M K+++ I LFPE N + T GS+ + L+ L P+YIRCIKPN+ K A + V Q+ YLGL EN+ VRRAGYA+R+ +E ++RY +L K+TWP W G + G++ L +I ++ G++K+FI++P +LF LE+ R+++ A +IQ +R H+L +++
Sbjct: 19 DMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSA-KVNGVDDAANFRTVRNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELTGIDQSVLERAFSFRTVEA---KQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREDIEWTHIDYFNNAIICDLIE-NNTNGILAMLDEECLRPGTVTDET---FLEKLNQVCATHQHFESRMSKCSRFLNDTSLPHSC-FRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKASHALIKSLFPEGNPAKINLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNEALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMKK 729
BLAST of Myosin IE vs. Ensembl Human
Match: MYO1B (myosin IB [Source:HGNC Symbol;Acc:HGNC:7596]) HSP 1 Score: 575.474 bits (1482), Expect = 0.000e+0 Identity = 303/720 (42.08%), Postives = 453/720 (62.92%), Query Frame = 3
Query: 114 DLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTP-DYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLF-----IEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRMNKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKIN--VAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSS---------------HSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRE 2204
D+VLL +++++ NLKKRF IYTYIG+V+I+VNP++ L I++ +++ Y+ YE PHI+A++D +R++ + QC++I+GESGAGKT ++K +M Y++ V G V Q+KE +L+SNP+LEAFGNAKTVRN+NSSRFGKY++I+FD G+P+GG IS +LLEKSRVV Q + ERNFH+FYQL+ G +++ + Y+YL+ KV+ DD + F+ +AM+++G E S+L++VAAVL LGN+ F + G +++ KDK L+ C L G+++S L + R + K++ + N QA+ ARDAL+K LYSR+F ++V++IN + + +G+LDIYGFEIF N FEQF INY NEKLQQIFIELTLK EQ+EY++E ++WT ++YFNN ++CDLIE N G+ ++LD+ C VTD F+ K++ H+ S HS F I HYAGKV Y+ EGF ++N D L D+ + M K+++ I LFPE N + T GS+ + L+ L P+YIRCIKPN+ K A + V Q+ YLGL EN+ VRRAGYA+R+ +E ++RY +L K+TWP W G + G++ L +I ++ G++K+FI++P +LF LE+ R+++ A +IQ +R H+L +++
Sbjct: 19 DMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSA-KVNGVDDAANFRTVRNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELTGIDQSVLERAFSFRTVEA---KQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREDIEWTHIDYFNNAIICDLIE-NNTNGILAMLDEECLRPGTVTDET---FLEKLNQVCATHQHFESRMSKCSRFLNDTSLPHSC-FRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKASHALIKSLFPEGNPAKINLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNEALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMKK 729
BLAST of Myosin IE vs. Ensembl Celegans
Match: hum-1 (Heavy chain, Unconventional Myosin [Source:UniProtKB/TrEMBL;Acc:Q19901]) HSP 1 Score: 1063.91 bits (2750), Expect = 0.000e+0 Identity = 563/1117 (50.40%), Postives = 743/1117 (66.52%), Query Frame = 3
Query: 75 HWQSKT-TKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRMN-KEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAI----NIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSK-EYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPEGFQGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTKPGNRDLRAIQAILPTLEKSGIRIKRADTKKVINQTQSFMKSNQ-QIDR---------NSTDKLPNLPQSGKAKFPSMSQMRMTPVMGVNPRQSQITDEELVKSVSKNSKRESNITDXXXXXXXXXXXXXXXXVNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKK 3374
HWQSK ++ DD+VLLPK+++ SI ENLKKR + I+TYIG VLI+VNPFK++ FT+KE+ +YQGAA YEN PHIYA+ADNM+RNM+ID ESQCVIISGESGAGKTV+AKFIM YIS++SGG +V+ IK++IL+SNPLLEAFGN+ TVRN NSSRFGKYVEI F RGGEPIGGK+S FLLEKSRVV QN+ +RNFH+FYQL G +K++R FGI YY+YLN SGV+K DDTDD EF++T+HAM+V+G+ +QL +L IVA VLH+GN+ F E A K L++P +LLGL +++ K+ R+M + +++ I + N +QA RDA KA+Y+R+FDY+V K+N AM I D+ ++GILDIYGFEIF NGFEQFCIN+VNEKLQQIFIELTLKAEQ+EYV+EG++WT ++YF+NK+VCDLIE K PPG+ S+LDD CA + +D + +T + S H+ S F I HYAG V+Y +GFC+RNRD L D+I +MQKS+ PFI LFPENV KR T T ++IR QAN LV L KC PHY+RCIKPNETK+ DWE RV QV YLGLRENI VRRAG+AYRR F+KF QRYAI+S +TWP + GD ++ + + + + Q+Q+GKTK+F+K+PESLFLLEE RERKF+ YA+VIQ +RQ +A K ++K +E+AADL Y KKERR +SLNRNF+GDY+ L+ +P L+ L+GKR++V F+ KYDR+F+ DL+LT + LIG++K+K G +KG+ +EVIKR+ D+ + I LSPY D+FV++ + +Y S++E FKTEF LSK Y E TN L L F + + K F K+ TV N A K + VS+ GLP+ T+P R P ++ R T++ QS+ ++ Q Q R N+ ++ P P S ++ S R+ PVMG + ++ ++S N + P P + V A+Y YEA D DELS G IEL+ +D GWW GK+ NR GL P NYVK+
Sbjct: 4 HWQSKVNVQHVGVDDMVLLPKLTEQSIVENLKKRLQANSIFTYIGPVLISVNPFKQMPYFTEKEMLLYQGAAQYENAPHIYALADNMYRNMLIDNESQCVIISGESGAGKTVNAKFIMNYISRISGGGQKVQHIKDVILQSNPLLEAFGNSATVRNWNSSRFGKYVEIVFSRGGEPIGGKLSNFLLEKSRVVHQNEGDRNFHVFYQLCAGADKNLRSTFGIGELQYYNYLNMSGVFKADDTDDGKEFESTLHAMKVVGVNDQDQLEVLRIVATVLHIGNITFTEENNFAAVSGKDYLEYPAFLLGLTSADIEAKLTGRKMESKWGTQKEEIDMKLNVEQASYTRDAWVKAIYARLFDYLVKKVNDAMNITSQSTSDNFSVGILDIYGFEIFNNNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVREGIKWTEIDYFDNKIVCDLIETKRPPGIMSLLDDTCAQNHGQREGVDRQLLTTLSKSFAGHPHFGPGSDSFVIKHYAGDVTYNVDGFCDRNRDVLYPDLILLMQKSSRPFIQALFPENVAASAGKRPT-TFSTKIRTQANTLVESLMKCSPHYVRCIKPNETKRPNDWEESRVKHQVEYLGLRENIRVRRAGFAYRRAFDKFAQRYAIVSPQTWPCFQGDQQRACEIICDSVHMEKNQYQMGKTKIFVKNPESLFLLEETRERKFDGYARVIQKAWRQFSARKQHIKQKEQAADLMYGKKERRRYSLNRNFVGDYIGLEHHPTLQSLVGKRQRVLFACTANKYDRKFRVTKLDLLLTVNHLTLIGKEKVKNGPEKGKIVEVIKRQFDLPQIKSIGLSPYQDDFVILYLGNDDYSSLLETPFKTEFCTALSKAYKERTNGTLHLDFRSSHVVSYKKMKFDFSDGKR---TVQFGNDGTSSAEKTLKPNGKVLNVSIGTGLPNTTRPSTE--RPQGGYTPRRDQL-----RTSTRRTKQNNQSYGQNGQSQAMRAPVPAHGMNNNYNQTP-APVSTNHQY-SQEPARI-PVMG------NVINQLNNMNLSGNGNSPAGRGPPPARGPKPPPPAKPKLNPVVIAVYPYEAQDVDELSFEAGAEIELMNKDASGWWQGKVNNRVGLFPGNYVKE 1100
BLAST of Myosin IE vs. Ensembl Celegans
Match: hum-5 (Heavy chain, Unconventional Myosin; Myosin IA [Source:UniProtKB/TrEMBL;Acc:G5ECZ0]) HSP 1 Score: 547.354 bits (1409), Expect = 7.059e-177 Identity = 298/724 (41.16%), Postives = 443/724 (61.19%), Query Frame = 3
Query: 111 DDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSG--GAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITT-PDYYSYLNQSGVYKVDDTDDKSEFKNTMHAME-VMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQA---EFKDKRSLQFPCYLLGLEESELATKMASREMA---DRMNKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAIN-----IDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSH-------STGFTIF---HYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKN-KRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETW--PKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKL 2198
+DLVLL I S+ +NL+ RF IYTYIG VL+AVNP+++L I+ + + Y+G YE PH++AIAD +R+M C++ISGESGAGKT ++K IM+Y++ ++ G +E++K ++L SN +LEAFG AKT RN+NSSRFGKY+ I FD G+P+GG IS +LLEKSRVV Q + ERNFH+FYQL+ G + + FG+T Y +LNQ +KV +D +F A+ + +K + S+ S++A ++HLGNV FI+G+ + +K +LQ L + ELA ++S+ +A D + K+ ++ A+ RDAL+KALY R+F ++V K+N A+++ IG+LDIYGFEIF N FEQ CINY NEKLQQ+FIEL LK EQ+EY +EG++W + YFNNKV+CDL+E+ G+ SILD+ CA+ VTD + F+ ++D + HY+S S GF F HYAG V+Y GF ++N+D L D+ ++ S N + LFP+ + R T G + ++LV +L + +PHYIRCIKPNE K + ++ +RV QV YLGL EN+ VRRAG+A+R P+++F+ RY ++ TW P+ +K ++++A + Q G+TK+FI+ P+++F LEE R + + +Q R V + Y ++
Sbjct: 14 EDLVLLSTIDLKSVVQNLQLRFQKGRIYTYIGEVLVAVNPYRQLGIYEKSTVDQYKGREIYERAPHVFAIADAAYRSMKRFGRDSCIVISGESGAGKTETSKIIMKYLAAITNVRQQGEIERVKNVLLRSNCILEAFGCAKTTRNDNSSRFGKYMHINFDYDGDPVGGNISNYLLEKSRVVRQQEGERNFHVFYQLVNGGDDGLLRQFGLTKDAKQYYFLNQGQSHKVASINDSRDFAEVQTALRSIHTFDKQDVESMWSVIAGLIHLGNVRFIDGENSSGAVHIAEKAALQNAARCLNVTPDELAKSLSSQVVAAHGDIVKKQHDV------NAAYYTRDALAKALYERLFSWMVSKVNEAISVQNSSRYSKSHVIGVLDIYGFEIFGTNSFEQLCINYCNEKLQQLFIELVLKQEQEEYEREGIKWVKIEYFNNKVICDLVEIPR-TGILSILDEACASIGNVTDKV---FLGELDKKLKSHKHYTSRNLKQSDKSMGFEEFKITHYAGDVTYSVMGFMDKNKDTLFQDLKRLLYHSKNRLVKSLFPDGSKSMAEVNRRPPTAGFLFKNSMSELVKQLAQKEPHYIRCIKPNEEKNSNVFDLERVEHQVRYLGLLENVRVRRAGFAHRMPYDRFVNRYKLICASTWPNPRRGQQLKDSCMQILESAGLAQDCVQ-GRTKIFIRSPQTVFRLEELRTEQLPNVITFLQKMVRGVQQRERYRRM 726
BLAST of Myosin IE vs. Ensembl Celegans
Match: hum-5 (Heavy chain, Unconventional Myosin; Myosin IA [Source:UniProtKB/TrEMBL;Acc:G5ECZ0]) HSP 1 Score: 547.354 bits (1409), Expect = 7.059e-177 Identity = 298/724 (41.16%), Postives = 443/724 (61.19%), Query Frame = 3
Query: 111 DDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSG--GAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITT-PDYYSYLNQSGVYKVDDTDDKSEFKNTMHAME-VMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQA---EFKDKRSLQFPCYLLGLEESELATKMASREMA---DRMNKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAIN-----IDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSH-------STGFTIF---HYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKN-KRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETW--PKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKL 2198
+DLVLL I S+ +NL+ RF IYTYIG VL+AVNP+++L I+ + + Y+G YE PH++AIAD +R+M C++ISGESGAGKT ++K IM+Y++ ++ G +E++K ++L SN +LEAFG AKT RN+NSSRFGKY+ I FD G+P+GG IS +LLEKSRVV Q + ERNFH+FYQL+ G + + FG+T Y +LNQ +KV +D +F A+ + +K + S+ S++A ++HLGNV FI+G+ + +K +LQ L + ELA ++S+ +A D + K+ ++ A+ RDAL+KALY R+F ++V K+N A+++ IG+LDIYGFEIF N FEQ CINY NEKLQQ+FIEL LK EQ+EY +EG++W + YFNNKV+CDL+E+ G+ SILD+ CA+ VTD + F+ ++D + HY+S S GF F HYAG V+Y GF ++N+D L D+ ++ S N + LFP+ + R T G + ++LV +L + +PHYIRCIKPNE K + ++ +RV QV YLGL EN+ VRRAG+A+R P+++F+ RY ++ TW P+ +K ++++A + Q G+TK+FI+ P+++F LEE R + + +Q R V + Y ++
Sbjct: 14 EDLVLLSTIDLKSVVQNLQLRFQKGRIYTYIGEVLVAVNPYRQLGIYEKSTVDQYKGREIYERAPHVFAIADAAYRSMKRFGRDSCIVISGESGAGKTETSKIIMKYLAAITNVRQQGEIERVKNVLLRSNCILEAFGCAKTTRNDNSSRFGKYMHINFDYDGDPVGGNISNYLLEKSRVVRQQEGERNFHVFYQLVNGGDDGLLRQFGLTKDAKQYYFLNQGQSHKVASINDSRDFAEVQTALRSIHTFDKQDVESMWSVIAGLIHLGNVRFIDGENSSGAVHIAEKAALQNAARCLNVTPDELAKSLSSQVVAAHGDIVKKQHDV------NAAYYTRDALAKALYERLFSWMVSKVNEAISVQNSSRYSKSHVIGVLDIYGFEIFGTNSFEQLCINYCNEKLQQLFIELVLKQEQEEYEREGIKWVKIEYFNNKVICDLVEIPR-TGILSILDEACASIGNVTDKV---FLGELDKKLKSHKHYTSRNLKQSDKSMGFEEFKITHYAGDVTYSVMGFMDKNKDTLFQDLKRLLYHSKNRLVKSLFPDGSKSMAEVNRRPPTAGFLFKNSMSELVKQLAQKEPHYIRCIKPNEEKNSNVFDLERVEHQVRYLGLLENVRVRRAGFAHRMPYDRFVNRYKLICASTWPNPRRGQQLKDSCMQILESAGLAQDCVQ-GRTKIFIRSPQTVFRLEELRTEQLPNVITFLQKMVRGVQQRERYRRM 726
BLAST of Myosin IE vs. Ensembl Celegans
Match: hum-6 (Unconventional myosin heavy chain 6 [Source:UniProtKB/Swiss-Prot;Acc:P91443]) HSP 1 Score: 454.521 bits (1168), Expect = 3.412e-135 Identity = 252/669 (37.67%), Postives = 383/669 (57.25%), Query Frame = 3
Query: 111 DDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIE----GQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRMNKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAM--AINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHY----SSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAIL-SKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKD 2084
+D+ L + +I NL R+ + IY Y G++LIAVNP+ ++I+T EI MY+ E PPHI+AIADN + NM + ++Q VIISGESGAGKT S K ++++++ +SG +EQ +LE+NP+LEAFGNAKT+RN+NSSRFGKY+++ F+ G G KI Q+LLEKSR+V Q++NERN+HIFY L+ G ++ + + T Y YL Q + DD ++ AM V+ + + E SI ++A++LH+GN+ F + + + D +L LL L E L + ++ + R E+ ++ N QQA ARDAL+KA+Y ++F +IV ++N A+ +IGILDI+GFE F N FEQ CIN+ NE LQQ F+ K EQ EY +E + W + + +N+ DLI + P + S++D+ D + K+ ++ + Y S F + H+AG V Y GF E+NRD S D+ ++ S PF+ LF + D + R +TVG++ R+ L+ +LT+ P +IRCIKPNE K+A + D V+ Q+ Y G+ E I +RR+GY R + F+ RY +L S P D+ + + + +Q+GKTK+F+KD
Sbjct: 65 EDMCQLGDFHESAILRNLFIRYREKLIYAYTGSILIAVNPYMDIAIYTADEIRMYKRKRIGELPPHIFAIADNAYTNMRREKKNQSVIISGESGAGKTESTKLVLQFLATISGQHSWIEQQ---VLEANPVLEAFGNAKTIRNDNSSRFGKYIDVHFNESGSIEGAKIEQYLLEKSRIVTQSENERNYHIFYCLLAGLSREEKSELELGTAADYYYLIQGKTLTAEGRDDAADLAEIRSAMRVLMINEQEIGSIFKLLASLLHIGNIRFRQNTNDNMESVDVADPSTLVRIAKLLQLHEQNLLDAITTKSLVTR---EERVISRLNGQQAVDARDALAKAIYGKLFIHIVRRVNDAIYKPSQSRRTSIGILDIFGFENFESNSFEQLCINFANETLQQFFVHHVFKMEQKEYDEEHINWRHIKFVDNQATVDLIA-QRPLNILSLIDEESI----FPKGTDKTMLLKLHSTHGRNELYLQPKSELQRAFGVTHFAGNVFYNTRGFLEKNRDSFSADLSVLISSSKMPFLARLFDDIEYD-TSSRKKVTVGNQFRRSLEQLMSQLTQTHPFFIRCIKPNEMKRALVMDRDLVLRQLRYSGMMETIKIRRSGYPIRHDYYPFVFRYRVLVSSIQGPVNRIDLHDAAKKICHMILGTNADYQLGKTKVFLKD 721
BLAST of Myosin IE vs. Ensembl Celegans
Match: nmy-1 (Non-muscle MYosin [Source:UniProtKB/TrEMBL;Acc:Q20641]) HSP 1 Score: 422.55 bits (1085), Expect = 2.181e-124 Identity = 249/707 (35.22%), Postives = 402/707 (56.86%), Query Frame = 3
Query: 111 DDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGA--------------------GRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQ--QAEFKDKRSLQFPCYLLGLEESELATK-MASREMADR--MNKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMN------IGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNY-FNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHY----SSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFP-------------ENVTDLKNKRSTLTVGSRIRK-QANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIK 2081
+D+ L +++ S+ NLK R+ IYTY G + +NP+KKL I+++ I ++G +E PPHI+AIAD +R+M+ + E Q ++ +GESGAGKT + K +++Y++ V+G + +++ +L++NP+LEAFGN+KTV+N+NSSRFGK++ I FD G G I +LLEKSRV+ Q Q+ER+FHIFYQ++ GC + + + D Y +L G+ + + DD EF +T+++M +MG DE SI+ +V+AVL LGN+ F + ++ QA +D R +Q C+LLGL EL + R R +NK Q N++QA A +A++KA Y R+F ++V +IN ++ D + IGILDI GFEIF N FEQ CINY NEKLQQ+F EQ+EY +EG++W +++ + + DLIE P GV ++LD+ C + D FV K+ ++ + + F + HYAG+V Y + + +N D L+ +V+ +MQ ST+PF+ ++ E +++++ S++ K Q L+ L PH++RCI PN KK+ ++ V++Q+ G+ E I + R G+ R PF++F RY IL+ + PK D K+ ++ ++ DI+ ++IG++K+F +
Sbjct: 81 EDMSELTYLNEASVLHNLKDRYYSSLIYTYSGLFCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKTENTKKVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKNDNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLLEGVDNYRFLVNRGIT-LPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQEKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQ------NQEQAEFAVEAIAKASYERLFKWLVTRINKSL----DRTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTMFILEQEEYQREGIEWDFIDFGLDLQPTIDLIE--KPMGVLALLDEECL----FPKANDKSFVEKLQKTHNKHPKFIVPDMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPFVAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNHEKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKNFIDGKESVRKMITALDIDTNLYRIGQSKVFFR 770
BLAST of Myosin IE vs. Ensembl Fly
Match: Myo61F (gene:FBgn0010246 transcript:FBtr0072673) HSP 1 Score: 580.867 bits (1496), Expect = 0.000e+0 Identity = 317/716 (44.27%), Postives = 449/716 (62.71%), Query Frame = 3
Query: 114 DLVLLPKI-SQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGC-EKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRMNKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMN----IGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTG------------FTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWP--KWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLR 2201
D VLL S+++ NLKKRF +D IYTYIG VLI+VNP+K+L I+T + Y+ YE PPHI+A+ DN FR+++ + QCV+ISGESG+GKT ++K ++++I+ SG VE +K+ +L+SNP+LEAFGNAKT RN+NSSRFGKY++IQFD G PIGG I +LLEKSRVV Q ERNFHIFYQL+ G E ++E+ D YSYL V +D FK A+ V+ K+EQ I IVA++LHLGNV F E + A+ + + LLG+ SEL + R + R + + N++ A ARDAL+KA+Y R+F ++V ++N+++ + +GILDIYGFEIF KN FEQFCIN+ NEKLQQ+FIELTLK+EQDEY +EG++W PV YF+NKV+C+LIE K+ G+ SILD+ C + + D F+ K+ HY H F + HYAG+V+Y GF ++N D L D+ E + K+ N + + FPE +L++ + T ++ R N+L+ L +P YIRCIKPN+ + A + ++ V+ QV YLGL EN+ VRRAG+AYRR +E F++RY LSK TWP K G K G+Q L+K ++ ++++G+TKLFI+ P +LF E+ + K + A +IQ ++ + + YLKLR
Sbjct: 15 DFVLLENYQSEEAFIGNLKKRFQEDLIYTYIGQVLISVNPYKQLPIYTDDHVKAYRNKHFYEMPPHIFAVTDNAFRSLIEENRGQCVLISGESGSGKTEASKKVLQFIAACSGNQTTVEGVKDKLLKSNPVLEAFGNAKTNRNDNSSRFGKYMDIQFDFKGAPIGGNILNYLLEKSRVVAQMGGERNFHIFYQLLAGADEALLQELRLERALDTYSYLTDGLNGTVTRINDADSFKQVQQALTVIDFTKEEQREIFGIVASILHLGNVGFTEVEGNAKVNSRDLVVTAARLLGVNASELEAALTHRTIDARGDV---VTSPLNQELAIYARDALAKAVYDRLFSWLVQRLNISLQAKETRASRNNVMGILDIYGFEIFQKNSFEQFCINFCNEKLQQLFIELTLKSEQDEYRREGIEWIPVEYFDNKVICNLIEEKH-KGIISILDEEC---LRPGEPTDKTFLEKLTQKLAQHHHYVCHEKAPAHIKKIMLRDEFRLVHYAGEVTYSVNGFLDKNNDLLFRDLKETLSKAGNGIVRNCFPEK--ELRSLKRPETAITQFRASLNNLMDILMCKEPSYIRCIKPNDLQTANVFNDELVLHQVKYLGLMENLRVRRAGFAYRRTYELFLERYKSLSKSTWPNYKGPGGPKAGVQQLVKDLGWDEEKYRVGETKLFIRWPRTLFDTEDAYQEKKHEIAAIIQAHWKGLMQRRKYLKLR 721
BLAST of Myosin IE vs. Ensembl Fly
Match: Myo61F (gene:FBgn0010246 transcript:FBtr0072672) HSP 1 Score: 580.867 bits (1496), Expect = 0.000e+0 Identity = 317/716 (44.27%), Postives = 449/716 (62.71%), Query Frame = 3
Query: 114 DLVLLPKI-SQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGC-EKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRMNKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMN----IGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTG------------FTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWP--KWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLR 2201
D VLL S+++ NLKKRF +D IYTYIG VLI+VNP+K+L I+T + Y+ YE PPHI+A+ DN FR+++ + QCV+ISGESG+GKT ++K ++++I+ SG VE +K+ +L+SNP+LEAFGNAKT RN+NSSRFGKY++IQFD G PIGG I +LLEKSRVV Q ERNFHIFYQL+ G E ++E+ D YSYL V +D FK A+ V+ K+EQ I IVA++LHLGNV F E + A+ + + LLG+ SEL + R + R + + N++ A ARDAL+KA+Y R+F ++V ++N+++ + +GILDIYGFEIF KN FEQFCIN+ NEKLQQ+FIELTLK+EQDEY +EG++W PV YF+NKV+C+LIE K+ G+ SILD+ C + + D F+ K+ HY H F + HYAG+V+Y GF ++N D L D+ E + K+ N + + FPE +L++ + T ++ R N+L+ L +P YIRCIKPN+ + A + ++ V+ QV YLGL EN+ VRRAG+AYRR +E F++RY LSK TWP K G K G+Q L+K ++ ++++G+TKLFI+ P +LF E+ + K + A +IQ ++ + + YLKLR
Sbjct: 15 DFVLLENYQSEEAFIGNLKKRFQEDLIYTYIGQVLISVNPYKQLPIYTDDHVKAYRNKHFYEMPPHIFAVTDNAFRSLIEENRGQCVLISGESGSGKTEASKKVLQFIAACSGNQTTVEGVKDKLLKSNPVLEAFGNAKTNRNDNSSRFGKYMDIQFDFKGAPIGGNILNYLLEKSRVVAQMGGERNFHIFYQLLAGADEALLQELRLERALDTYSYLTDGLNGTVTRINDADSFKQVQQALTVIDFTKEEQREIFGIVASILHLGNVGFTEVEGNAKVNSRDLVVTAARLLGVNASELEAALTHRTIDARGDV---VTSPLNQELAIYARDALAKAVYDRLFSWLVQRLNISLQAKETRASRNNVMGILDIYGFEIFQKNSFEQFCINFCNEKLQQLFIELTLKSEQDEYRREGIEWIPVEYFDNKVICNLIEEKH-KGIISILDEEC---LRPGEPTDKTFLEKLTQKLAQHHHYVCHEKAPAHIKKIMLRDEFRLVHYAGEVTYSVNGFLDKNNDLLFRDLKETLSKAGNGIVRNCFPEK--ELRSLKRPETAITQFRASLNNLMDILMCKEPSYIRCIKPNDLQTANVFNDELVLHQVKYLGLMENLRVRRAGFAYRRTYELFLERYKSLSKSTWPNYKGPGGPKAGVQQLVKDLGWDEEKYRVGETKLFIRWPRTLFDTEDAYQEKKHEIAAIIQAHWKGLMQRRKYLKLR 721
BLAST of Myosin IE vs. Ensembl Fly
Match: Myo61F (gene:FBgn0010246 transcript:FBtr0072675) HSP 1 Score: 580.482 bits (1495), Expect = 0.000e+0 Identity = 317/716 (44.27%), Postives = 449/716 (62.71%), Query Frame = 3
Query: 114 DLVLLPKI-SQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGC-EKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRMNKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMN----IGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTG------------FTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWP--KWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLR 2201
D VLL S+++ NLKKRF +D IYTYIG VLI+VNP+K+L I+T + Y+ YE PPHI+A+ DN FR+++ + QCV+ISGESG+GKT ++K ++++I+ SG VE +K+ +L+SNP+LEAFGNAKT RN+NSSRFGKY++IQFD G PIGG I +LLEKSRVV Q ERNFHIFYQL+ G E ++E+ D YSYL V +D FK A+ V+ K+EQ I IVA++LHLGNV F E + A+ + + LLG+ SEL + R + R + + N++ A ARDAL+KA+Y R+F ++V ++N+++ + +GILDIYGFEIF KN FEQFCIN+ NEKLQQ+FIELTLK+EQDEY +EG++W PV YF+NKV+C+LIE K+ G+ SILD+ C + + D F+ K+ HY H F + HYAG+V+Y GF ++N D L D+ E + K+ N + + FPE +L++ + T ++ R N+L+ L +P YIRCIKPN+ + A + ++ V+ QV YLGL EN+ VRRAG+AYRR +E F++RY LSK TWP K G K G+Q L+K ++ ++++G+TKLFI+ P +LF E+ + K + A +IQ ++ + + YLKLR
Sbjct: 24 DFVLLENYQSEEAFIGNLKKRFQEDLIYTYIGQVLISVNPYKQLPIYTDDHVKAYRNKHFYEMPPHIFAVTDNAFRSLIEENRGQCVLISGESGSGKTEASKKVLQFIAACSGNQTTVEGVKDKLLKSNPVLEAFGNAKTNRNDNSSRFGKYMDIQFDFKGAPIGGNILNYLLEKSRVVAQMGGERNFHIFYQLLAGADEALLQELRLERALDTYSYLTDGLNGTVTRINDADSFKQVQQALTVIDFTKEEQREIFGIVASILHLGNVGFTEVEGNAKVNSRDLVVTAARLLGVNASELEAALTHRTIDARGDV---VTSPLNQELAIYARDALAKAVYDRLFSWLVQRLNISLQAKETRASRNNVMGILDIYGFEIFQKNSFEQFCINFCNEKLQQLFIELTLKSEQDEYRREGIEWIPVEYFDNKVICNLIEEKH-KGIISILDEEC---LRPGEPTDKTFLEKLTQKLAQHHHYVCHEKAPAHIKKIMLRDEFRLVHYAGEVTYSVNGFLDKNNDLLFRDLKETLSKAGNGIVRNCFPEK--ELRSLKRPETAITQFRASLNNLMDILMCKEPSYIRCIKPNDLQTANVFNDELVLHQVKYLGLMENLRVRRAGFAYRRTYELFLERYKSLSKSTWPNYKGPGGPKAGVQQLVKDLGWDEEKYRVGETKLFIRWPRTLFDTEDAYQEKKHEIAAIIQAHWKGLMQRRKYLKLR 730
BLAST of Myosin IE vs. Ensembl Fly
Match: Myo61F (gene:FBgn0010246 transcript:FBtr0072674) HSP 1 Score: 580.482 bits (1495), Expect = 0.000e+0 Identity = 317/716 (44.27%), Postives = 449/716 (62.71%), Query Frame = 3
Query: 114 DLVLLPKI-SQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGC-EKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRMNKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMN----IGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTG------------FTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWP--KWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLR 2201
D VLL S+++ NLKKRF +D IYTYIG VLI+VNP+K+L I+T + Y+ YE PPHI+A+ DN FR+++ + QCV+ISGESG+GKT ++K ++++I+ SG VE +K+ +L+SNP+LEAFGNAKT RN+NSSRFGKY++IQFD G PIGG I +LLEKSRVV Q ERNFHIFYQL+ G E ++E+ D YSYL V +D FK A+ V+ K+EQ I IVA++LHLGNV F E + A+ + + LLG+ SEL + R + R + + N++ A ARDAL+KA+Y R+F ++V ++N+++ + +GILDIYGFEIF KN FEQFCIN+ NEKLQQ+FIELTLK+EQDEY +EG++W PV YF+NKV+C+LIE K+ G+ SILD+ C + + D F+ K+ HY H F + HYAG+V+Y GF ++N D L D+ E + K+ N + + FPE +L++ + T ++ R N+L+ L +P YIRCIKPN+ + A + ++ V+ QV YLGL EN+ VRRAG+AYRR +E F++RY LSK TWP K G K G+Q L+K ++ ++++G+TKLFI+ P +LF E+ + K + A +IQ ++ + + YLKLR
Sbjct: 41 DFVLLENYQSEEAFIGNLKKRFQEDLIYTYIGQVLISVNPYKQLPIYTDDHVKAYRNKHFYEMPPHIFAVTDNAFRSLIEENRGQCVLISGESGSGKTEASKKVLQFIAACSGNQTTVEGVKDKLLKSNPVLEAFGNAKTNRNDNSSRFGKYMDIQFDFKGAPIGGNILNYLLEKSRVVAQMGGERNFHIFYQLLAGADEALLQELRLERALDTYSYLTDGLNGTVTRINDADSFKQVQQALTVIDFTKEEQREIFGIVASILHLGNVGFTEVEGNAKVNSRDLVVTAARLLGVNASELEAALTHRTIDARGDV---VTSPLNQELAIYARDALAKAVYDRLFSWLVQRLNISLQAKETRASRNNVMGILDIYGFEIFQKNSFEQFCINFCNEKLQQLFIELTLKSEQDEYRREGIEWIPVEYFDNKVICNLIEEKH-KGIISILDEEC---LRPGEPTDKTFLEKLTQKLAQHHHYVCHEKAPAHIKKIMLRDEFRLVHYAGEVTYSVNGFLDKNNDLLFRDLKETLSKAGNGIVRNCFPEK--ELRSLKRPETAITQFRASLNNLMDILMCKEPSYIRCIKPNDLQTANVFNDELVLHQVKYLGLMENLRVRRAGFAYRRTYELFLERYKSLSKSTWPNYKGPGGPKAGVQQLVKDLGWDEEKYRVGETKLFIRWPRTLFDTEDAYQEKKHEIAAIIQAHWKGLMQRRKYLKLR 747
BLAST of Myosin IE vs. Ensembl Fly
Match: Myo31DF (gene:FBgn0086347 transcript:FBtr0304138) HSP 1 Score: 539.65 bits (1389), Expect = 6.018e-174 Identity = 285/691 (41.24%), Postives = 430/691 (62.23%), Query Frame = 3
Query: 96 KNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGR--VEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGC-EKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMA---DRMNKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMN------IGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSS-----------HSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDL-KNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKW-TGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPES 2093
+ + D VLL ++S + +NL+KRF + IYTYIG V +++NP+++++I+ + I Y+G +EN PH++AIAD+ +R + + C++ISGESGAGKT ++K IM+YI+ V+ G+ +E++K ++++SN +LE FGNAKT RN+NSSRFGKY++I+FD +P+GG I+ +LLEKSRVV Q ERNFH FYQL+ G + ++R+ Y YLNQ +D +KS++K T +A + +G DE +I +AAVLHLGNV F + + +K+ L+ LL + E+EL+T + R +A + M K+ N QA +DAL+KA+Y R+F +I+ +IN A+ IG+LDIYGFEIF N FEQFCINY NEKLQQ+FIEL LK EQ+EY +EG++WT + YFNNK++CDL+E + G+ +I+D+ C + KVT D+ + MD + HY+S H F I HYAG V Y GF E+N+D L D ++ S + + +++PE D+ K + LT G+ ++ DLVV L K +P Y+RCIKPN+ K + ++ +RV QV YLGL EN+ VRRAG+ +R+ ++KF+ RY ++S+ TWP + G + G++ L++ + G TK+FI+ P +
Sbjct: 5 REAGVQDFVLLDQVSMEKFMDNLRKRFQNGSIYTYIGEVCVSMNPYRQMNIYGPETIRKYKGRELFENAPHLFAIADSAYRVLKQRQQDTCILISGESGAGKTEASKIIMKYIAAVTNAQGQNEIERVKNVLIQSNAILETFGNAKTNRNDNSSRFGKYMDIEFDYKADPVGGIITNYLLEKSRVVQQQPGERNFHSFYQLLRGANDNELRQYELQKETGKYHYLNQGS---MDILTEKSDYKGTCNAFKTLGFSTDEVQTIWRTIAAVLHLGNVEFQTIEDELVISNKQHLKSTAKLLQVTETELSTALTKRVIAAGGNVMQKDHNAT------QAEYGKDALAKAIYDRLFTWIISRINRAILFRGSKTQARFNSVIGVLDIYGFEIFDSNSFEQFCINYCNEKLQQLFIELVLKQEQEEYQREGIEWTNIEYFNNKIICDLVEQPH-KGIIAIMDEACLSVGKVT---DDTLLGAMDKNLSKHPHYTSRQLKPTDKELKHREDFRITHYAGDVIYNINGFIEKNKDTLYQDFKRLLHNSKDANLSEMWPEGAQDIKKTTKRPLTAGTLFQRSMADLVVTLLKKEPFYVRCIKPNDLKSSTVFDEERVEHQVRYLGLLENLRVRRAGFVHRQRYDKFLLRYKMISQYTWPNFRAGSDRDGVRVLIEEKKFAQ-DVKYGHTKIFIRSPRT 681
BLAST of Myosin IE vs. Ensembl Zebrafish
Match: myo1eb (myosin IEb [Source:ZFIN;Acc:ZDB-GENE-040426-1347]) HSP 1 Score: 1180.62 bits (3053), Expect = 0.000e+0 Identity = 608/1111 (54.73%), Postives = 781/1111 (70.30%), Query Frame = 3
Query: 63 KNMHHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRM-NKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELK-NPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPEG---FQGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTKPGNRDLRAIQAILPTLEKSGIRIKRADTKKVINQTQSFMKSNQQIDRNSTDKLPNLPQ-SGKAKFPSMSQMRMTPVMGVNPRQSQITDEELVKSVSKNSKRESNITDXXXXXXXXXXXXXXXXVNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 3377
K +HWQ++ K S DD+VLL KI++D+IT+NLKKR+MDD I+TYIG VLI+VNPFK+L FT +EI +YQGAA YENPPHIYA+ADNM+RNMMID E+QCVIISGESGAGKTV+AK+IM YISKVSGG +V+ +K+IIL+SNPLLEAFGNAKTVRNNNSSRFGKY EIQF RGGEP GGKIS FLLEKSRVV QN ERNFHI+YQL++G K+ RE G+TTPDYY YLNQS Y V+D +DK EF++TM+AM V+GL D Q S+L IVA +LHLGN+ F E A + + L FP YLLG+ + L +K+ SR M + K + I + N +QA RDALSKALYSR+FDY+VD IN AM + +++NIG+LDIYGFEIF KNGFEQFCIN+VNEKLQQIFIELTLKAEQ+EYVQEG+ WTP+ YFNNKVVCDLIE K NPPG+ SILDDVCAT + D + K+ +H++S + GF + HYAGKVSY+ GFCERNRD L D+IE+MQ S FI LFPEN+ K R T T GS+I+KQAN LV L KC PHYIRCIKPNETKK+RDWE RV QV YLGLRENI VRRAGYA+RR F+KF+ RYAIL++ETWP+W GD K+G+ HL+K+ +++ Q+Q+GKTK+FIK PESLFLLEE RERK+N YA+VIQ +R+ A + Y+++RE A+DL NKKERR++SLNRNF+GDY+ D +P++R +G+RE+++F+ V KYDRRFK + RDLILT KF+YLIGR+K+KQG +KGQ EV+KRK+++ + ++LS D+ ++ +YDSV++ FKTEF+ +L KR+ E T + L LKF+ ++ F VK G F S++I F + + S S +TVS+ GLP NT+P RD R + + +S + R K + + + ST P LP+ G + SQ+ MG ++ D+ + + SK + +P +P R +ALYAY+A DTDELS P DIIE++ ED GWW G++ + G+ P NYV+K+
Sbjct: 4 KEKYHWQTQNVKVSGVDDMVLLSKITEDAITDNLKKRYMDDYIFTYIGPVLISVNPFKQLPYFTDREIELYQGAAQYENPPHIYALADNMYRNMMIDSENQCVIISGESGAGKTVAAKYIMSYISKVSGGGPKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRVVSQNNGERNFHIYYQLLKGATKEQRENLGVTTPDYYFYLNQSDTYTVEDVNDKKEFEDTMNAMSVVGLSMDAQDSVLQIVAGILHLGNIAFREEGNYAVVESEDFLAFPSYLLGINQDGLKSKLTSRIMDSKWGGKTETISVTLNTEQASFTRDALSKALYSRLFDYLVDAINKAMQKDREELNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGISWTPIEYFNNKVVCDLIESKLNPPGIMSILDDVCATMHAKGEGADQTLLQKLQSQIGTHEHFNSWNKGFVVHHYAGKVSYDVSGFCERNRDVLFSDIIELMQSSEFAFIKGLFPENIEAEKRGRPT-TAGSKIKKQANTLVQTLMKCTPHYIRCIKPNETKKSRDWEESRVKHQVEYLGLRENIRVRRAGYAFRRIFKKFLHRYAILTRETWPQWRGDEKQGVLHLLKSVNMDSDQYQLGKTKIFIKAPESLFLLEEMRERKYNGYARVIQQAWRKHIAVRKYVRMREEASDLLLNKKERRKNSLNRNFVGDYIGTDNHPEIRQFVGRRERIDFADVVVKYDRRFKSVKRDLILTPKFLYLIGREKVKQGPEKGQIREVLKRKIEVEKIQSVSLSTLQDDIFILH-EDQYDSVLQSVFKTEFLSLLYKRFEEKTKKKLPLKFNNLLEFKVKKGGWGPFASAGSRQIQFQMGQGDDAVLKPS------SKILTVSIGSGLPKNTRPTRRDNRK-SSFMGNQNRSAGQYSREAPKSAGRGRGQPAVRHSLLRQQSTMDQPTLPRLQGSVRSQRESQVYTD--MGF----MKVPDQGVAGMHRRRSKEYKPLPG---SGRPKPSPKPVPRTPRCKALYAYDAQDTDELSFQPDDIIEILSEDPSGWWQGRLRGKEGMFPGNYVEKM 1096
BLAST of Myosin IE vs. Ensembl Zebrafish
Match: myo1eb (myosin IEb [Source:ZFIN;Acc:ZDB-GENE-040426-1347]) HSP 1 Score: 1177.93 bits (3046), Expect = 0.000e+0 Identity = 607/1108 (54.78%), Postives = 779/1108 (70.31%), Query Frame = 3
Query: 72 HHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRM-NKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELK-NPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPEG---FQGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTKPGNRDLRAIQAILPTLEKSGIRIKRADTKKVINQTQSFMKSNQQIDRNSTDKLPNLPQ-SGKAKFPSMSQMRMTPVMGVNPRQSQITDEELVKSVSKNSKRESNITDXXXXXXXXXXXXXXXXVNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 3377
+HWQ++ K S DD+VLL KI++D+IT+NLKKR+MDD I+TYIG VLI+VNPFK+L FT +EI +YQGAA YENPPHIYA+ADNM+RNMMID E+QCVIISGESGAGKTV+AK+IM YISKVSGG +V+ +K+IIL+SNPLLEAFGNAKTVRNNNSSRFGKY EIQF RGGEP GGKIS FLLEKSRVV QN ERNFHI+YQL++G K+ RE G+TTPDYY YLNQS Y V+D +DK EF++TM+AM V+GL D Q S+L IVA +LHLGN+ F E A + + L FP YLLG+ + L +K+ SR M + K + I + N +QA RDALSKALYSR+FDY+VD IN AM + +++NIG+LDIYGFEIF KNGFEQFCIN+VNEKLQQIFIELTLKAEQ+EYVQEG+ WTP+ YFNNKVVCDLIE K NPPG+ SILDDVCAT + D + K+ +H++S + GF + HYAGKVSY+ GFCERNRD L D+IE+MQ S FI LFPEN+ K R T T GS+I+KQAN LV L KC PHYIRCIKPNETKK+RDWE RV QV YLGLRENI VRRAGYA+RR F+KF+ RYAIL++ETWP+W GD K+G+ HL+K+ +++ Q+Q+GKTK+FIK PESLFLLEE RERK+N YA+VIQ +R+ A + Y+++RE A+DL NKKERR++SLNRNF+GDY+ D +P++R +G+RE+V+F+ V KYDRRFK + RDLILT KF+YLIGR+K+KQG +KGQ EV+KRK+++ + ++LS D+ ++ +YDSV++ FKTEF+ +L KR+ E T + L LKF+ ++ F VK G F S++I F + + S S +TVS+ GLP NT+P RD R + + +S + R K + + + ST P LP+ G + SQ+ MG ++ D+ + + SK + +P +P R +ALY Y+A DTDELS P DIIE++ ED GWW G++ + G+ P NYV+K+
Sbjct: 1 YHWQTQNVKVSGVDDMVLLSKITEDAITDNLKKRYMDDYIFTYIGPVLISVNPFKQLPYFTDREIELYQGAAQYENPPHIYALADNMYRNMMIDSENQCVIISGESGAGKTVAAKYIMSYISKVSGGGPKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRVVSQNNGERNFHIYYQLLKGATKEQRENLGVTTPDYYFYLNQSDTYTVEDVNDKKEFEDTMNAMSVVGLSMDAQDSVLQIVAGILHLGNIAFREEGNYAVVESEDFLAFPSYLLGINQDGLKSKLTSRIMDSKWGGKTETISVTLNTEQASFTRDALSKALYSRLFDYLVDAINKAMQKDREELNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGISWTPIEYFNNKVVCDLIESKLNPPGIMSILDDVCATMHAKGEGADQTLLQKLQSQIGTHEHFNSWNKGFVVHHYAGKVSYDVSGFCERNRDVLFSDIIELMQSSEFAFIKGLFPENIEAEKRGRPT-TAGSKIKKQANTLVQTLMKCTPHYIRCIKPNETKKSRDWEESRVKHQVEYLGLRENIRVRRAGYAFRRIFKKFLHRYAILTRETWPQWRGDEKQGVLHLLKSVNMDSDQYQLGKTKIFIKAPESLFLLEEMRERKYNGYARVIQQAWRKHIAVRKYVRMREEASDLLLNKKERRKNSLNRNFVGDYIGTDNHPEIRQFVGRRERVDFADVVVKYDRRFKSVKRDLILTPKFLYLIGREKVKQGPEKGQIREVLKRKIEVEKIQSVSLSTLQDDIFILH-EDQYDSVLQSVFKTEFLSLLYKRFEEKTKKKLPLKFNNLLEFKVKKGGWGPFASAGSRQIQFQMGQGDDAVLKPS------SKILTVSIGSGLPKNTRPTRRDNRK-SSFMGNQNRSAGQYSREAPKSAGRGRGQPAVRHSLLRQQSTMDQPTLPRLQGSVRSQRESQVYTD--MGF----MKVPDQGVAGMHRRRSKEYKPLPG---SGRPKPSPKPVPRTPRCKALYTYDAQDTDELSFQPDDIIEILSEDPSGWWQGRLRGKEGMFPGNYVEKM 1090
BLAST of Myosin IE vs. Ensembl Zebrafish
Match: myo1ea (myosin IEa [Source:ZFIN;Acc:ZDB-GENE-030131-5127]) HSP 1 Score: 1163.67 bits (3009), Expect = 0.000e+0 Identity = 611/1123 (54.41%), Postives = 777/1123 (69.19%), Query Frame = 3
Query: 72 HHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRM-NKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELK-NPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPE---GFQGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTKPGNRDLRAIQA-------ILPTLEKSGIRIKRADTK-KVINQTQSFMKSNQQIDRNSTDK--LPN----LPQSGKAKFPSMSQMRM--TPVMGVNPRQSQITDEELVKSVSKNSKRESNITDXXXXXXXXXXXXXXXXVNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 3377
+HWQS K S DD+VLL KI++D+I ENLKKR+MDD I+TYIG VLI+VNPFK++ F +KEI MYQGAA YENPPHIYA+ADNM+RNMMID E+QCVIISGESGAGKTV+AK+IM YISKVSGG RV+ +K+IIL+SNPLLEAFGNAKTVRNNNSSRFGKY EIQF GGEP GGKIS FLLEKSRVV++N ER+FHIFYQLIEG D + GIT+ DYY+YLNQSG YKVDD +DK +F+ T+HAM+V+G+ ++ +L IVA +LHLGN+ F E A ++ L FP +LLG+++ L K+ SR+M + K ++I + N +QA RDALSKAL+SR+FDY+V+ IN AM ++NIG+LDIYGFEIF KNGFEQFCIN+VNEKLQQIFIELTLKAEQDEYVQEG++WT + YFNNK+VCDLIE K NPPG+ SILDDVCAT + D + K+ N +H++S + GF I HYAGKVSY+ EGFCERNRD L D+IE+MQ S FI LFPEN+ K R T T GS+I+KQANDLV L KC PHYIRCIKPNETKK +DWE RV QV YLGL+ENI VRRAGYAYRR F KF+ RYAIL+KE+WP W GD K+G+ HL+++ +++ Q+Q+G TK+FIK PESLFLLEE RERKF+ YA+ IQ +R+ A K Y+++RE A+DL NKKERR HSLNRNF+GDYL +D+ P+LR +GKREK++F+ V K+DRRFK + RDLILT K +YLIGR+K+KQG +KG EV+KRK+D+ + ++LS D+F+++ EYDS++E FKTEFI +L++RY E T R L LK+ + +K E + G S+++ F DVA V + + VS+ GLP N++P + + Q PT G + + K N S +NQ+ +T + LP L + G P + P G R Q TD + R+S G +P +P V + +ALYAY+A DTDELS DIIE+++ED GWWTG++ + GL P+NYV KI
Sbjct: 9 YHWQSHNVKQSGVDDMVLLSKINEDAIVENLKKRYMDDYIFTYIGPVLISVNPFKQMPYFGEKEIEMYQGAAQYENPPHIYALADNMYRNMMIDRENQCVIISGESGAGKTVAAKYIMGYISKVSGGGPRVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSSGGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASGDQKSSLGITSLDYYTYLNQSGSYKVDDINDKHDFQETLHAMDVIGISGIDRTMVLQIVAGILHLGNINFREAGNYAAVENDEFLAFPAFLLGIDQERLKEKLTSRKMDGKWGGKSESIDVTLNVEQACFTRDALSKALHSRVFDYLVESINKAMVKEHQELNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQDEYVQEGIRWTQIEYFNNKIVCDLIESKINPPGIMSILDDVCATMHAKGEGADQTMLQKLRMQINNHEHFNSWNQGFIIHHYAGKVSYDAEGFCERNRDVLFTDLIELMQSSEIAFIRALFPENLNAEKKGRPT-TAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPKDWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFRKFLNRYAILTKESWPTWRGDEKQGVLHLLRSVNMDQDQYQLGHTKIFIKAPESLFLLEETRERKFDGYARTIQTAWRKYCARKKYVQMREEASDLLLNKKERRRHSLNRNFVGDYLGMDDRPELRQFMGKREKIDFADKVNKFDRRFKSIKRDLILTPKSVYLIGREKVKQGPEKGLVKEVLKRKIDVEKILAVSLSTLQDDFMILH-EDEYDSLLECVFKTEFISLLARRYEERTQRKLPLKYSNTMEMKLKKEKWGPWNAGGSRQVQFMQG----QGDVA--VLRPSNKMLQVSIGPGLPKNSRPTKKGITQSQPNRSRTHHHTPTRAAPGPPVAHQNGGLKNANHRNSQHHNNQRPTSENTARPFLPTNVSQLKERGSRHAPQQPNLDFLRVPDQGAAGRNRQPTDN------GGMAHRQSTNRPAPGGGRPKPAPKPKPQVPQCKALYAYDAQDTDELSFNADDIIEIIKEDASGWWTGRLRGKQGLFPNNYVTKI 1117
BLAST of Myosin IE vs. Ensembl Zebrafish
Match: myo1f (myosin IF [Source:ZFIN;Acc:ZDB-GENE-081104-506]) HSP 1 Score: 1148.27 bits (2969), Expect = 0.000e+0 Identity = 596/1113 (53.55%), Postives = 768/1113 (69.00%), Query Frame = 3
Query: 72 HHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADR-MNKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELK-NPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPEGFQGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTKPGNRDLRAIQAILPTLEKSGIRIKRADTKKVINQTQSFMK--SNQQIDRNSTDKLP---NLPQSGKAKFPSMSQMRMTPVMGVNPRQSQITDEELV----KSVSKNSKRESNITDXXXXXXXXXXXXXXXXVNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 3377
+HWQS+ K S DD+VLL KI++D+I ENLKKRF+DD I+TYIG VLI+VNPFK++ FT +EI +YQGAA YENPPHIYA+ DNM+RNMMID E+QCVIISGESGAGKTV+AK+IM YISKVSGG +V+ +K+IIL+SNPLLEAFGNAKTVRNNNSSRFGKY EIQF RGGEP GGKIS FLLEKSRVV QN+NERNFHIFYQLI+GC +E GI TPDYY YLNQSG YKVD T+D +F+ TM AM+V+G+ + Q L IVA +LHLG++ FIE + + L FP YLLG++++ L K+ SR M + K ++I + N +QA RDAL+KALY+R+FDY+V++IN AM I+++++G+LDIYGFEIF +NGFEQFCIN+VNEKLQQIFIELTLKAEQ+EYVQEG++WTP+ YFNNK+VCDLIE K +PPG+ S+LDDVCAT D D + K+ + DH++S ++GF I HYAGKVSY+ GFCERNRD L D+IE+MQ S FI LFPEN+ K R T T GS+I++QAN+LV L KC PHYIRCIKPNETK+ +DWE R QV YLGLRENI VRRAG+AYRR F KF+ RYAIL+ ETWP W G ++G+ HL++T ++ Q+Q+G++K+FIK+PESLFLLEE RERKF+ +A+ IQ +R+ A + Y ++RE A+D+ YN KERR +S+NRNF+GDYL +++ P+LR + KRE+V+F+ V K+DRRFK + RDLIL+ K IYLIGR+KIK+G +KGQ EV+KR+LDIS + ++LS D+F ++ + EYDS++E FKTEF+ +L KRY E T L L F + F VK EG+ GGS++ + F Q D A G +TVSV GLP +KP + + + G R + N F + QQ + T +P N P S K S R G P Q+Q T+ + + + +S +++S P + R ALY Y D DE+S DIIEL+ ED GWW G+I + GL P NYV+KI
Sbjct: 5 YHWQSQNVKQSGVDDMVLLSKITEDAIVENLKKRFLDDYIFTYIGPVLISVNPFKQMPYFTDREIELYQGAAQYENPPHIYALTDNMYRNMMIDSENQCVIISGESGAGKTVAAKYIMGYISKVSGGGSKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRVVSQNENERNFHIFYQLIDGCTPQQKEGLGIMTPDYYYYLNQSGTYKVDGTNDSKDFQETMEAMQVIGIPEMHQTLALQIVAGILHLGSINFIEVGNYGQVESTDLLAFPAYLLGIDQNRLQEKLTSRIMDSKWAGKTESINVTLNLEQARHTRDALAKALYTRLFDYLVEEINKAMQKPIEELSVGVLDIYGFEIFQRNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIKWTPIEYFNNKIVCDLIENKLSPPGIMSVLDDVCATMHATKDGADMTLLQKLQNAVGTHDHFNSWNSGFIIHHYAGKVSYDINGFCERNRDVLFPDLIELMQSSQYDFIQSLFPENLNTDKKGRPT-TAGSKIKRQANELVSTLMKCTPHYIRCIKPNETKRPKDWEESRARHQVEYLGLRENIRVRRAGFAYRRIFPKFLHRYAILTAETWPCWRGAEQQGVLHLLRTVNMETDQYQMGRSKIFIKNPESLFLLEEMRERKFDTFARTIQKAWRKYIARRKYEQMREEASDILYNSKERRRNSINRNFVGDYLGMEDRPELRQFMAKRERVDFADSVNKFDRRFKSIKRDLILSPKSIYLIGREKIKKGPEKGQIKEVLKRRLDISGIRSVSLSTRQDDFFILHET-EYDSLLESMFKTEFLTLLCKRYEEQTRSKLTLSFSDRLQFNVKKEGWGGGSTRMVVF----QRGQADEAVIKAG--GKTLTVSVGDGLPKTSKPTRKGMP---------QSHGGRSQPQHRGGHQNGAAQFHRGGGQQQQQKEVTYSMPVRHNPPPSNPLKLGSQKNQR-----GSRPVQNQSTNLDFLNVPDQGMSGMQRKKSISQRPPPAPSSRPKPQARPQGPRCRALYQYFGQDVDEISFEVNDIIELLSEDQSGWWRGRIRGKEGLFPGNYVEKI 1095
BLAST of Myosin IE vs. Ensembl Zebrafish
Match: myo1ea (myosin IEa [Source:ZFIN;Acc:ZDB-GENE-030131-5127]) HSP 1 Score: 981.86 bits (2537), Expect = 0.000e+0 Identity = 517/993 (52.06%), Postives = 679/993 (68.38%), Query Frame = 3
Query: 423 MEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRMN-KEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELK-NPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPE---GFQGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTKPGNRDLRAIQAILPTLEKS--GIRIKRADTKKVINQTQSFMKSNQQIDRNSTDKLPNLPQSGKAKFPS-MSQMRMTPVMGVNPRQSQITDEELVKSVSKNSKRESNITDXXXXXXXXXXXXXXXXVNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 3377
M YISKVSGG RV+ +K+IIL+SNPLLEAFGNAKTVRNNNSSRFGKY EIQF GGEP GGKIS FLLEKSRVV++N ER+FHIFYQLIEG D + GIT+ DYY+YLNQSG YKVDD +DK +F+ T+HAM+V+G+ ++ +L IVA +LHLGN+ F E A ++ L FP +LLG+++ L K+ SR+M + K ++I + N +QA RDALSKAL+SR+FDY+V+ IN AM ++NIG+LDIYGFEIF KNGFEQFCIN+VNEKLQQIFIELTLKAEQDEYVQEG++WT + YFNNK+VCDLIE K NPPG+ SILDDVCAT + D + K+ N +H++S + GF I HYAGKVSY+ EGFCERNRD L D+IE+MQ S FI LFPEN+ K R T T GS+I+KQANDLV L KC PHYIRCIKPNETKK +DWE RV QV YLGL+ENI VRRAGYAYRR F KF+ RYAIL+KE+WP W GD K+G+ HL+++ +++ Q+Q+G TK+FIK PESLFLLEE RERKF+ YA+ IQ +R+ A K Y+++RE A+DL NKKERR HSLNRNF+GDYL +D+ P+LR +GKREK++F+ V K+DRRFK + RDLILT K +YLIGR+K+KQG +KG EV+KRK+D+ + ++LS D+F+++ EYDS++E FKTEFI +L++RY E T R L LK+ + +K E + G S+++ F DVA V + + VS+ GLP N++P + + Q P ++ + A V +Q +N + ++ ++ P + + P+ +SQ++ P+Q + + + + R+S G +P +P V + +ALYAY+A DTDELS DIIE+++ED GWWTG++ + GL P+NYV KI
Sbjct: 1 MGYISKVSGGGPRVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSSGGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASGDQKSSLGITSLDYYTYLNQSGSYKVDDINDKHDFQETLHAMDVIGISGIDRTMVLQIVAGILHLGNINFREAGNYAAVENDEFLAFPAFLLGIDQERLKEKLTSRKMDGKWGGKSESIDVTLNVEQACFTRDALSKALHSRVFDYLVESINKAMVKEHQELNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQDEYVQEGIRWTQIEYFNNKIVCDLIESKINPPGIMSILDDVCATMHAKGEGADQTMLQKLRMQINNHEHFNSWNQGFIIHHYAGKVSYDAEGFCERNRDVLFTDLIELMQSSEIAFIRALFPENLNAEKKGRPT-TAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPKDWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFRKFLNRYAILTKESWPTWRGDEKQGVLHLLRSVNMDQDQYQLGHTKIFIKAPESLFLLEETRERKFDGYARTIQTAWRKYCARKKYVQMREEASDLLLNKKERRRHSLNRNFVGDYLGMDDRPELRQFMGKREKIDFADKVNKFDRRFKSIKRDLILTPKSVYLIGREKVKQGPEKGLVKEVLKRKIDVEKILAVSLSTLQDDFMILH-EDEYDSLLECVFKTEFISLLARRYEERTQRKLPLKYSNTMEMKLKKEKWGPWNAGGSRQVQFMQG----QGDVA--VLRPSNKMLQVSIGPGLPKNSRPTKKGITQSQ---PNRSRTHHHTPTRAAPGPPVAHQNGGLKNANHRNSQHHNNQRPTSENTARPFLPTNVSQLKERGSRHA-PQQPNLDFLRVPDQGAAGAHRQSTNRPAPGGGRPKPAPKPKPQVPQCKALYAYDAQDTDELSFNADDIIEIIKEDASGWWTGRLRGKQGLFPNNYVTKI 981
BLAST of Myosin IE vs. Ensembl Xenopus
Match: MYO1E (myosin IE [Source:HGNC Symbol;Acc:HGNC:7599]) HSP 1 Score: 1186.02 bits (3067), Expect = 0.000e+0 Identity = 620/1123 (55.21%), Postives = 796/1123 (70.88%), Query Frame = 3
Query: 72 HHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRM-NKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELK-NPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPEGF----QGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTKPGNRDLR------------AIQAILPT--LEKSGIRIKRADTKKVINQTQSFMKSNQQIDRNSTDKLPNLPQSGKAKFPSMSQMRMTPVMGVNPRQSQITDEELVKSVS-KNSKRESNITDXXXXXXXXXXXXXXXXVNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 3377
+HWQS K+S DD+VLL KI++DSI +NLKKR+MDD I+TYIG VLI+VNPFK++ F KEI MYQGAA YENPPHIYA+ADNM+RNM+ID E+QCVIISGESGAGKTV+AK+IM YISKVSGG +V+ +K+IIL+SNPLLEAFGNAKTVRNNNSSRFGKY EIQF GGEP GGKIS FLLEKSRVV++N ER+FHIFYQLIEG KD RE GIT+ DYY+YLNQSG YKVDD +DK +F+ TMHAM V+G+ + Q ++ IVA VLHLGN+ F E A +++ L FP +LLG+ +S L K+ SR+M + K ++I + N +QA RDALSKAL+SR+FDY+VD IN AM + ++ NIG+LDIYGFEIF KNGFEQFCIN+VNEKLQQIFIELTLKAEQ+EYVQEG++WTP+ YFNNK+VCDLIE K NPPGV SILDDVCAT V + D + K+ + +H++S + GF I HYAGKVSY+ +GFCERNRD L +D+IE+MQ S PF+ LFPEN+ K R T T GS+I+KQANDLV L KC PHYIRCIKPNETKK RDWE RV QV YLGL+ENI VRRAGYAYRR F+KF+QRYAIL+KETWP W GD KKG+ HL+ + +++ Q+Q+GKTK+FIK PESLFLLEE RERK++ YA+ IQ +R+ A K Y+++RE+A+DLF NKKERR +S+NRNFIGDY+ +DE P+LR +GKREK++F+ V KYDRR K + RDLILT K +YLIGRDK+KQG +KG EV+K+K+D+ + ++LS D+F ++ +EYDS++E FKTEFI +LSK Y E T R L LKF+ +++ +K E + G S+++ F D+A V S + VS+ +GLP N++P R++ I+A P ++GI + + + + +N ++ +S D P LP+ ++T NP+Q Q D V ++R+S +P +P V + +ALYAY+A DTDELS DIIE+++ED+ GWWTGK+ + GL P+NYV KI
Sbjct: 9 YHWQSHNVKHSGVDDMVLLSKITEDSIVDNLKKRYMDDFIFTYIGPVLISVNPFKQMPYFGDKEIEMYQGAAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISKVSGGGPKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASKDQRESLGITSLDYYNYLNQSGSYKVDDINDKRDFQETMHAMNVIGISAEGQAMVMQIVAGVLHLGNIGFKEKGNYAAVENEEFLAFPAFLLGINQSRLKDKLTSRQMDSKWGGKSESINVTLNVEQACYTRDALSKALHSRVFDYLVDSINKAMKKDHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIEYFNNKIVCDLIENKVNPPGVMSILDDVCATMHAVGEGADQTLLQKLQMAVGTHEHFNSWNQGFIIHHYAGKVSYDVDGFCERNRDVLFMDLIELMQSSQQPFMQALFPENLQAEKKGRPT-TAGSKIKKQANDLVNTLMKCTPHYIRCIKPNETKKPRDWEESRVKHQVEYLGLKENIRVRRAGYAYRRVFKKFLQRYAILTKETWPSWKGDEKKGVLHLLHSVNMDSDQFQLGKTKIFIKAPESLFLLEEMRERKYDGYARSIQKAWRKYVARKKYVQMREQASDLFLNKKERRRNSINRNFIGDYIGMDERPELRQFVGKREKIDFADTVTKYDRRSKGVKRDLILTPKSVYLIGRDKMKQGPEKGLVKEVLKKKIDVERILSVSLSTMQDDFFILH-EQEYDSLLESLFKTEFISLLSKHYEEKTQRKLPLKFNNILDMKLKKENWGPWSGGAGSRQVQFIQG----FGDLA--VLKHSSKVLQVSIGQGLPKNSRPTRRNITNGRGNASKSKSYPIRAAPPPPGAHQNGIIMNPPFGHQPPKAARPY--NNSRMSHSSADH-PTLPR------------QVTGSSTRNPQQPQSLDFLRVPDQGVAGARRQSTNRPPPAGGRPKPQPKPKPHVPQCKALYAYDAQDTDELSFNANDIIEIIKEDSSGWWTGKLRGKQGLFPNNYVTKI 1108
BLAST of Myosin IE vs. Ensembl Xenopus
Match: MYO1E (myosin IE [Source:HGNC Symbol;Acc:HGNC:7599]) HSP 1 Score: 1177.16 bits (3044), Expect = 0.000e+0 Identity = 619/1109 (55.82%), Postives = 791/1109 (71.33%), Query Frame = 3
Query: 72 HHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRMN-KEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELK-NPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPEGFQ----GGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTKPGNRDLRAIQAILPTLEKSGIRIKRADTKKVINQTQSFMKSNQQIDRNSTDKLPNLPQSGKAKFPSMSQMRMTPVMGVNPRQSQITDEELVKSVS-KNSKRESNITDXXXXXXXXXXXXXXXXVNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 3377
+HWQS K+S DD+VLL KI++DSI +NLKKR+MDD I+TYIG VLI+VNPFK++ F KEI MYQGAA YENPPHIYA+ADNM+RNM+ID E+QCVIISGESGAGKTV+AK+IM YISKVSGG +V+ +K+IIL+SNPLLEAFGNAKTVRNNNSSRFGKY EIQF GGEP GGKIS FLLEKSRVV++N ER+FHIFYQLIEG KD RE GIT+ DYY+YLNQSG YKVDD +DK +F+ TMHAM V+G+ + Q ++ IVA VLHLGN+ F E A +++ L FP +LLG+ +S L K+ SR+M + K ++I + N +QA RDALSKAL+SR+FDY+VD IN AM + ++ NIG+LDIYGFEIF KNGFEQFCIN+VNEKLQQIFIELTLKAEQ+EYVQEG++WTP+ YFNNK+VCDLIE K NPPGV SILDDVCAT V + D + K+ + +H++S + GF I HYAGKVSY+ +GFCERNRD L +D+IE+MQ S+ PF+ LFPEN+ K R T T GS+I+KQANDLV L KC PHYIRCIKPNETKK RDWE RV QV YLGL+ENI VRRAGYAYRR F+KF+QRYAIL+KETWP W GD KKG+ HL+ + +++ Q+Q+GKTK+FIK PESLFLLEE RERK++ YA+ IQ +R+ A K Y+++RE+A+DLF NKKERR +S+NRNFIGDY+ +DE P+LR +GKREK++F+ V KYDRR K + RDLILT K +YLIGRDK+KQG +KG EV+K+K+D+ + ++LS D+F ++ +EYDS++E FKTEFI +LSK Y E T R L LKF+ +++ +K E + G S+++ F D+A V S + VS+ +GLP N+ R RA Q +GI + + + + +N ++ +S D P LP+ ++T NP+Q Q D V ++R+S +P +P V + +ALYAY+A DTDELS DIIE+++ED+ GWWTGK+ + GL P+NYV KI
Sbjct: 9 YHWQSHNVKHSGVDDMVLLSKITEDSIVDNLKKRYMDDFIFTYIGPVLISVNPFKQMPYFGDKEIEMYQGAAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISKVSGGGPKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASKDQRESLGITSLDYYNYLNQSGSYKVDDINDKRDFQETMHAMNVIGISAEGQAMVMQIVAGVLHLGNIGFKEKGNYAAVENEEFLAFPAFLLGINQSRLKDKLTSRQMDSKWGGKSESINVTLNVEQACYTRDALSKALHSRVFDYLVDSINKAMKKDHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIEYFNNKIVCDLIENKVNPPGVMSILDDVCATMHAVGEGADQTLLQKLQMAVGTHEHFNSWNQGFIIHHYAGKVSYDVDGFCERNRDVLFMDLIELMQ-SSQPFMQALFPENLQAEKKGRPT-TAGSKIKKQANDLVNTLMKCTPHYIRCIKPNETKKPRDWEESRVKHQVEYLGLKENIRVRRAGYAYRRVFKKFLQRYAILTKETWPSWKGDEKKGVLHLLHSVNMDSDQFQLGKTKIFIKAPESLFLLEEMRERKYDGYARSIQKAWRKYVARKKYVQMREQASDLFLNKKERRRNSINRNFIGDYIGMDERPELRQFVGKREKIDFADTVTKYDRRSKGVKRDLILTPKSVYLIGRDKMKQGPEKGLVKEVLKKKIDVERILSVSLSTMQDDFFILH-EQEYDSLLESLFKTEFISLLSKHYEEKTQRKLPLKFNNILDMKLKKENWGPWSGGAGSRQVQFIQGF----GDLA--VLKHSSKVLQVSIGQGLPKNS----RKQRAHQ--------NGIIMNPPFGHQPPKAARPY--NNSRMSHSSADH-PTLPR------------QVTGSSTRNPQQPQSLDFLRVPDQGVAGARRQSTNRPPPAGGRPKPQPKPKPHVPQCKALYAYDAQDTDELSFNANDIIEIIKEDSSGWWTGKLRGKQGLFPNNYVTKI 1081
BLAST of Myosin IE vs. Ensembl Xenopus
Match: MYO1E (myosin IE [Source:HGNC Symbol;Acc:HGNC:7599]) HSP 1 Score: 1167.91 bits (3020), Expect = 0.000e+0 Identity = 612/1109 (55.18%), Postives = 787/1109 (70.96%), Query Frame = 3
Query: 72 HHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRM-NKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELK-NPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPEGF----QGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTKPGNRDLRAIQAILPTLEKSGIRIKRADTKKVINQTQSFMKSNQQIDRNSTDKLPNLPQSGKAKFPSMSQMRMTPVMGVNPRQSQITDEELVKSVS-KNSKRESNITDXXXXXXXXXXXXXXXXVNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 3377
+HWQS K+S DD+VLL KI++DSI +NLKKR+MDD I+TYIG VLI+VNPFK++ F KEI MYQGAA YENPPHIYA+ADNM+RNM+ID E+QCVIISGESGAGKTV+AK+IM YISKVSGG +V+ +K+IIL+SNPLLEAFGNAKTVRNNNSSRFGKY EIQF GGEP GGKIS FLLEKSRVV++N ER+FHIFYQ+ G KD RE GIT+ DYY+YLNQSG YKVDD +DK +F+ TMHAM V+G+ + Q ++ IVA VLHLGN+ F E A +++ L FP +LLG+ +S L K+ SR+M + K ++I + N +QA RDALSKAL+SR+FDY+VD IN AM + ++ NIG+LDIYGFEIF KNGFEQFCIN+VNEKLQQIFIELTLKAEQ+EYVQEG++WTP+ YFNNK+VCDLIE K NPPGV SILDDVCAT V + D + K+ + +H++S + GF I HYAGKVSY+ +GFCERNRD L +D+IE+MQ S+ PF+ LFPEN+ K R T T GS+I+KQANDLV L KC PHYIRCIKPNETKK RDWE RV QV YLGL+ENI VRRAGYAYRR F+KF+QRYAIL+KETWP W GD KKG+ HL+ + +++ Q+Q+GKTK+FIK PESLFLLEE RERK++ YA+ IQ +R+ A K Y+++RE+A+DLF NKKERR +S+NRNFIGDY+ +DE P+LR +GKREK++F+ V KYDRR K + RDLILT K +YLIGRDK+KQG +KG EV+K+K+D+ + ++LS D+F ++ +EYDS++E FKTEFI +LSK Y E T R L LKF+ +++ +K E + G S+++ F D+A V S + VS+ +GLP N++ ++GI + + + + +N ++ +S D P LP+ ++T NP+Q Q D V ++R+S +P +P V + +ALYAY+A DTDELS DIIE+++ED+ GWWTGK+ + GL P+NYV KI
Sbjct: 11 YHWQSHNVKHSGVDDMVLLSKITEDSIVDNLKKRYMDDFIFTYIGPVLISVNPFKQMPYFGDKEIEMYQGAAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISKVSGGGPKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQVRIGASKDQRESLGITSLDYYNYLNQSGSYKVDDINDKRDFQETMHAMNVIGISAEGQAMVMQIVAGVLHLGNIGFKEKGNYAAVENEEFLAFPAFLLGINQSRLKDKLTSRQMDSKWGGKSESINVTLNVEQACYTRDALSKALHSRVFDYLVDSINKAMKKDHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIEYFNNKIVCDLIENKVNPPGVMSILDDVCATMHAVGEGADQTLLQKLQMAVGTHEHFNSWNQGFIIHHYAGKVSYDVDGFCERNRDVLFMDLIELMQ-SSQPFMQALFPENLQAEKKGRPT-TAGSKIKKQANDLVNTLMKCTPHYIRCIKPNETKKPRDWEESRVKHQVEYLGLKENIRVRRAGYAYRRVFKKFLQRYAILTKETWPSWKGDEKKGVLHLLHSVNMDSDQFQLGKTKIFIKAPESLFLLEEMRERKYDGYARSIQKAWRKYVARKKYVQMREQASDLFLNKKERRRNSINRNFIGDYIGMDERPELRQFVGKREKIDFADTVTKYDRRSKGVKRDLILTPKSVYLIGRDKMKQGPEKGLVKEVLKKKIDVERILSVSLSTMQDDFFILH-EQEYDSLLESLFKTEFISLLSKHYEEKTQRKLPLKFNNILDMKLKKENWGPWSGGAGSRQVQFIQG----FGDLA--VLKHSSKVLQVSIGQGLPKNSR-------------KQTHQNGIIMNPPFGHQPPKAARPY--NNSRMSHSSADH-PTLPR------------QVTGSSTRNPQQPQSLDFLRVPDQGVAGARRQSTNRPPPAGGRPKPQPKPKPHVPQCKALYAYDAQDTDELSFNANDIIEIIKEDSSGWWTGKLRGKQGLFPNNYVTKI 1082
BLAST of Myosin IE vs. Ensembl Xenopus
Match: MYO1E (myosin IE [Source:HGNC Symbol;Acc:HGNC:7599]) HSP 1 Score: 1135.94 bits (2937), Expect = 0.000e+0 Identity = 605/1125 (53.78%), Postives = 777/1125 (69.07%), Query Frame = 3
Query: 72 HHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIY---TYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRM-NKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELK-NPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPEGF----QGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTKPGNRDLR------------AIQAILPT--LEKSGIRIKRADTKKVINQTQSFMKSNQQIDRNSTDKLPNLPQSGKAKFPSMSQMRMTPVMGVNPRQSQITDEELVKSVSKNSKRESNITDXXXXXXXXXXXXXXXXVNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 3377
+HWQS K+S DD+VLL KI++DSI +NLKKR+MDD I+ TYIG VLI+VNPFK++ F KEI MYQGAA YENPPHIYA+ADNM+RNM+ID E+QCVIISGESGAGKTV+AK+IM YISKVSGG +V+ +K+IIL+SNPLLEAFGNAKTVRNNNSSRFGKY EIQF GGEP GGKIS FLLEKSRVV++N ER+FHIFYQLIEG KD RE GIT+ DYY+YLNQSG YKVDD +DK +F+ TMHAM V+G+ + Q ++ IVA VLHLGN+ F E A +++ L FP +LLG+ +S L K+ SR+M + K ++I + N +QA RDALSKAL+SR+FDY+VD IN AM + ++ NIG+LDIYGFEIF KNGFEQFCIN+VNEKLQQIFIELTLKAEQ+EYVQEG++WTP+ YFNNK+VCDLIE K NPPGV SILDDVCAT V + D + K+ + +H++S + GF I HYAGKVSY+ +GFCERNRD L +D+IE+MQ S PF+ LFPEN+ K R T T GS+I+KQANDLV L KC PHYIRCIKPNETKK RDWE RV QV YLGL+ENI VRRAGYAYRR F+KF+QRYAIL+KETWP W GD KKG+ HL+ + +++ Q+Q+GKTK+FIK PESLFLLEE RERK++ YA+ IQ +R+ A K Y+++RE+A+DLF NKKERR +S+NRNFIGDY+ +DE P+LR +GKREK++F+ V KYDRR K + RDLILT K +YLIGRDK+KQG +KG EV+K+K+D+ + ++LS D+F ++ +EYDS++E FKTEFI +LSK Y E T R L LKF+ +++ +K E + G S+++ F D+A V S + VS+ +GLP N++P R++ I+A P ++GI + + + + +N ++ +S D P LP+ ++T NP+Q Q D V S+I D T + +A +A D L ++ ++ GWWTGK+ + GL P+NYV KI
Sbjct: 9 YHWQSHNVKHSGVDDMVLLSKITEDSIVDNLKKRYMDDFIFVSLTYIGPVLISVNPFKQMPYFGDKEIEMYQGAAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISKVSGGGPKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASKDQRESLGITSLDYYNYLNQSGSYKVDDINDKRDFQETMHAMNVIGISAEGQAMVMQIVAGVLHLGNIGFKEKGNYAAVENEEFLAFPAFLLGINQSRLKDKLTSRQMDSKWGGKSESINVTLNVEQACYTRDALSKALHSRVFDYLVDSINKAMKKDHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIEYFNNKIVCDLIENKVNPPGVMSILDDVCATMHAVGEGADQTLLQKLQMAVGTHEHFNSWNQGFIIHHYAGKVSYDVDGFCERNRDVLFMDLIELMQSSQQPFMQALFPENLQAEKKGRPT-TAGSKIKKQANDLVNTLMKCTPHYIRCIKPNETKKPRDWEESRVKHQVEYLGLKENIRVRRAGYAYRRVFKKFLQRYAILTKETWPSWKGDEKKGVLHLLHSVNMDSDQFQLGKTKIFIKAPESLFLLEEMRERKYDGYARSIQKAWRKYVARKKYVQMREQASDLFLNKKERRRNSINRNFIGDYIGMDERPELRQFVGKREKIDFADTVTKYDRRSKGVKRDLILTPKSVYLIGRDKMKQGPEKGLVKEVLKKKIDVERILSVSLSTMQDDFFILH-EQEYDSLLESLFKTEFISLLSKHYEEKTQRKLPLKFNNILDMKLKKENWGPWSGGAGSRQVQFIQG----FGDLA--VLKHSSKVLQVSIGQGLPKNSRPTRRNITNGRGNASKSKSYPIRAAPPPPGAHQNGIIMNPPFGHQPPKAARPY--NNSRMSHSSADH-PTLPR------------QVTGSSTRNPQQPQSLDFLRVPDQGVAGLWRSDIVD-LATAALQCKTTGPHKTSTTKAAFA----DMKWLK-------QINTCNSSGWWTGKLRGKQGLFPNNYVTKI 1098
BLAST of Myosin IE vs. Ensembl Xenopus
Match: MYO1F (myosin IF [Source:NCBI gene;Acc:100493342]) HSP 1 Score: 1129.39 bits (2920), Expect = 0.000e+0 Identity = 572/1120 (51.07%), Postives = 774/1120 (69.11%), Query Frame = 3
Query: 66 NMHHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRM-NKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELK-NPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPEGFQGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTKPGNRDLRAIQAILPTLEKSGIRIKRADTKKVINQTQSFMKSNQQIDRNSTDKLPNLPQSGKAKFPSMSQM----RMTPVMGV----NPRQSQITDEELVKSVS------KNSKRESNITDXXXXXXXXXXXXXXXXVNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 3377
N +HWQS+ K S DD+VLL KI++D+I ENLKKR++DD I+TYIG+VLI+VNPFK++ FT++EI +YQGAA YENPPHIYA+ DNM+RNM+ID E+QCVIISGESGAGKTV+AK+IM YISKVSGG +V+ +K+IIL+SNPLLEAFGNAKTVRNNNSSRFGKY EIQF RGGEP GGKIS FLLEKSRVV QN+NERNFH+FYQLIEG + R+ GI TPDY+ YLNQS YKV+ T+DK +F + AM V+G+ +EQ +L I A +LHLGN+ F E A+ + L FP YLLG+++ L K+ SR+M + + ++I + N +QA RDALSKALY+R+FD++V+ IN AM ++ +IG+LDIYGFEIF KNGFEQFCIN+VNEKLQQIFIELTLKAEQ+EYV EG++WTP+ YFNNK+VCDLIE K NPPG+ S+LDDVCAT D + K+ + +H+S+ + GF I HYAGKVSY EGFCERNRD L +D+IE+MQ S FI LFPE + K R T T GS+I+KQANDLV L KC PHYIRCIKPNETKK +DWE RV QV YLGL+ENI VRRAG+AYRR F KF+QRYAIL++ETWP+W GD ++G+QHL+++ +++ Q+Q+GK+K+F+K+PESLFLLEE RERKF+ +A+ IQ +R+ A + Y ++RE A+++ Y KERR +S+NRNF+GDYL +++ P+LR + KRE+++F+ V KYDRRFK + RDLIL+ K++YLIGR+K+K+G +KGQ E++K+K++I + I+LS D+F ++ ++D+++E FKTEFI ++ KRY EIT+R L+L F + VK EG+ GG ++ + F + Q + VQ + +S+ GLP N+KP T+K Q++ + RN + P G ++ PS +Q+ R P + PR+S++ + + ++ ++R ++T + P + R +A+Y Y D DELS ++I+++ ED GWW G++ + GL P NYV+KI
Sbjct: 4 NRYHWQSQNVKQSGVDDMVLLSKITEDAIVENLKKRYLDDYIFTYIGSVLISVNPFKQMPYFTEREIELYQGAAQYENPPHIYALTDNMYRNMLIDGENQCVIISGESGAGKTVAAKYIMGYISKVSGGGSKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRVVSQNENERNFHVFYQLIEGASDEQRQNLGIMTPDYFFYLNQSETYKVEGTNDKKDFYEMLEAMMVIGVSAEEQQMVLQISAGILHLGNISFQEQGNYAKVECPDLLDFPAYLLGVQKGRLNDKLTSRKMDSKWGGRSESITVTLNVEQASYTRDALSKALYARVFDFLVESINKAMQKPYEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVAEGIRWTPIEYFNNKIVCDLIENKLNPPGIMSVLDDVCATMHATGGGADQTLLQKLQAAVGTHEHFSNWNLGFVIHHYAGKVSYYVEGFCERNRDVLFIDLIELMQSSEYQFIQSLFPERLDSDKKSRPT-TAGSKIKKQANDLVNTLMKCTPHYIRCIKPNETKKPKDWEESRVKHQVEYLGLKENIRVRRAGFAYRRVFNKFLQRYAILTQETWPRWRGDERQGVQHLLRSVNMDSDQYQMGKSKVFVKNPESLFLLEEMRERKFDTFARTIQKAWRRYIARRKYEQMREEASNILYGYKERRRNSINRNFVGDYLGMEDRPELRQFMTKRERIDFADSVSKYDRRFKSIKRDLILSPKYLYLIGREKVKKGPEKGQIKEILKKKVEIMNIQSISLSTRQDDFFILQ-EVDHDTLMESVFKTEFISLMCKRYEEITSRKLRLNFTDTLQLRVKKEGWGGGGTRNLQF-IRGQGEIA-----VQKAGGKTLVISIGDGLPKNSKP--------------------------TRKGAPQSRGHRAPPSRSFRNGAPQFP----KGTSRNPSYAQVPRQPRAPPSAALPKQTAPRRSRVPSDHNMDFLNVPDQGVAGAQRRKSVTHRPPPAVGRPKPQSKPAGPRCKAIYQYIGQDVDELSFNVNEVIDIILEDPSGWWKGRLHGKEGLFPGNYVQKI 1085
BLAST of Myosin IE vs. Ensembl Mouse
Match: Myo1f (myosin IF [Source:MGI Symbol;Acc:MGI:107711]) HSP 1 Score: 1136.32 bits (2938), Expect = 0.000e+0 Identity = 585/1117 (52.37%), Postives = 769/1117 (68.85%), Query Frame = 3
Query: 63 KNMHHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRM-NKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELK-NPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPEGFQGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTKPGNRDL------RAIQAILPTLEKSGIRIKRADTKKVINQTQSFMKSNQQIDRN-STDKLPNLPQS---GKAKFPSMSQMRMTPVMGVNPRQSQITDEELVKSVSKNSKRESNITDXXXXXXXXXXXXXXXXVNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 3377
K HWQS K S DD+VLLP+I++D+I NL+KRFMDD I+TYIG+VLI+VNPFK++ FT +EI +YQGAA YENPPHIYA+ DNM+RNM+ID E+QCVIISGESGAGKTV+AK+IM YISKVSGG +V+ +K+IIL+SNPLLEAFGNAKTVRNNNSSRFGKY EIQF RGGEP GGKIS FLLEKSRVV+QN+NERNFHI+YQL+EG ++ ++ G+ TPDYY YLNQS YKV+ TDD+S+F T+ AM+V+G+ Q +L +VA +LHLGN+ F E A + L FP YLLG++ L K+ SR+M + + ++I + N +QA RDAL+K LY+R+FD++V+ IN AM ++ +IG+LDIYGFEIF KNGFEQFCIN+VNEKLQQIFIELTLKAEQ+EYVQEG++WTP+ YFNNK+VCDLIE K +PPG+ S+LDDVCAT D + K+ + +H++S S GF I HYAGKVSY+ GFCERNRD L D+IE+MQ S F+ LFPE + K R + T GS+I+KQANDLV L KC PHYIRCIKPNETK+ RDWE RV QV YLGLRENI VRRAG+AYRR F KF+QRYAIL+ ETWP+W GD ++G+QHL++ ++ Q+Q+G TK+F+K+PESLFLLEE RERKF+ +A+ IQ +R+ A + Y ++RE A+++ NKKERR +S+NRNF+GDYL L+E P+LR + KRE+V+F+ V KYDRRFK + RDLILT K +Y+IGR+K+K+G +KG EV+K+KLDI AL ++LS D+F ++ + DS +E FKTEF+ +L KR+ E R L L F ++ F VK EG+ GGS++ +TF+ T D+A G A+T+S+ GLP +TKP + L R+ QA PT G R + + + +I S+ + P P S G ++ P R P + + D+ + +R+ +I + P +P R ALY Y D DELS ++IE++ ED+ GWW G++ + GL P NYV+KI
Sbjct: 4 KERFHWQSHNVKQSGVDDMVLLPQITEDAIVSNLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGGDKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQQQNLGLMTPDYYYYLNQSDTYKVEGTDDRSDFSETLSAMQVIGIPTSVQQLVLQLVAGILHLGNISFCEEGNYARVESVDLLAFPAYLLGIDSGRLQEKLTSRKMDSKWGGRSESIDVTLNVEQAAYTRDALAKGLYARLFDFLVEAINRAMQKPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIEYFNNKIVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKLQAAVGTHEHFNSWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQSSDQDFLRMLFPEKLNIDKKGRPS-TAGSKIKKQANDLVSTLKKCTPHYIRCIKPNETKRPRDWEESRVKHQVEYLGLRENIRVRRAGFAYRRQFSKFLQRYAILTPETWPRWRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEMRERKFDGFARTIQKAWRRHVAVRKYEEMREEASNILLNKKERRRNSINRNFVGDYLGLEERPELRQFLAKRERVDFADSVTKYDRRFKPIKRDLILTPKCVYVIGREKVKRGPEKGLVREVLKKKLDIQALRGVSLSTRQDDFFILQ-EEAADSFLESIFKTEFVSLLCKRFEEAARRPLPLTFSDLLQFRVKKEGWGGGSTRNVTFSRG----TSDLAVLKAG--GRALTISIGDGLPKSTKPTRKGLAQGRPRRSAQA--PTRAAPG--PPRGLNRNGVPPSSQVRSLPLEITSGRSSQRPPRGPPSSTLGASRRP-----RARPPSEHSTEFLNVPDQGVA-----GMQRKRSIGQRPVPGVGRPKPQPRTHGPRCRALYQYIGQDVDELSFNVNEVIEILIEDSSGWWKGRLHGQEGLFPGNYVEKI 1098
BLAST of Myosin IE vs. Ensembl Mouse
Match: Myo1e (myosin IE [Source:MGI Symbol;Acc:MGI:106621]) HSP 1 Score: 1135.17 bits (2935), Expect = 0.000e+0 Identity = 586/1119 (52.37%), Postives = 781/1119 (69.79%), Query Frame = 3
Query: 72 HHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRM-NKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELK-NPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPEG---FQGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTKPGNRDLRAIQAILPTLEKSGIRIKRADTKKVINQTQSFMKSNQQIDRNSTDKLPNLPQSGKAKFPSMSQMRMTPVMGVNPRQSQITDEELVKSVSK------------NSKRESNITDXXXXXXXXXXXXXXXXVNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 3377
+HWQS K+S DD+VLL KI++ SI ENLKKR+MDD I+TYIG+VLI+VNPFK++ F +KE+ MYQGAA YENPPHIYA+AD+M+RNM+ID E+QCVIISGESGAGKTV+AK+IM Y+S+VSGG +V+ +K+IIL+SNPLLEAFGNAKTVRNNNSSRFGKY EIQF GGEP GGKIS FLLEKSRVV++N ER+FHIFYQLIEG + ++ GIT+ DYY YL+ SG YKVDD DDK +F+ T+HAM V+G+ +EQ +L IVA +LHLGN+ F E A + + L FP YLLG+ + L K+ SR+M + K ++I + N +QA RDAL+KAL++R+FD++VD IN AM + ++ NIG+LDIYGFEIF KNGFEQFCIN+VNEKLQQIFIELTLKAEQ+EYVQEG++WTP+ YFNNK+VCDLIE K NPPG+ SILDDVCAT V + D + K+ + +H++S + GF I HYAGKVSY+ +GFCERNRD L +D+IE+MQ S PFI LFPEN+ K R T T GS+I+KQANDLV L KC PHYIRCIKPNETKK +DWE RV QV YLGL+ENI VRRAGYAYRR F+KF+QRYAIL+K TWP W GD K+G+ HL+++ +++ Q+Q+G++K+FIK PESLFLLEE RERK++ YA+VIQ +R+ A K Y+++RE A+DL NKKERR +S+NRNFIGDY+ ++E P+L+ +GKREK++F+ V KYDRRFK + RDL+LT K +YLIGR+K+KQG KG EV+KR++++ + ++LS D+ ++ +EYDS++E FKTEF+ +L+KRY E T + L LKF + +K E + G S+++ F D+A + + + VS+ GLP N++P R+ + P K+ ++ A +Q + RN P+ + ++ S+ P + PRQ + L ++ +R+++ +P +P V + +ALYAY+A DTDELS DII++++ED GWWTG++ + GL P+NYV KI
Sbjct: 9 YHWQSHNVKHSGVDDMVLLSKITESSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEVEMYQGAAQYENPPHIYALADSMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYVSRVSGGGPKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASPEQKQSLGITSMDYYYYLSLSGSYKVDDIDDKRDFQETLHAMNVIGIFSEEQTLVLQIVAGILHLGNISFKEVGNYAAVESEEFLAFPAYLLGINQDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSINKAMEKDHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIEYFNNKIVCDLIESKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQIGSHEHFNSWNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELPFIKSLFPENLQADKKGRPT-TAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPKDWEESRVKHQVEYLGLKENIRVRRAGYAYRRVFQKFLQRYAILTKATWPVWRGDEKQGVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKTWRKFVARKKYVQMREEASDLLLNKKERRRNSINRNFIGDYIGMEERPELQQFVGKREKIDFADTVTKYDRRFKGVKRDLLLTPKCLYLIGREKVKQGPDKGVVKEVLKRRIEVERILSVSLSTMQDDIFILH-EQEYDSLLESVFKTEFLSLLAKRYEEKTQKQLPLKFSNTLELKLKKENWGPWSAGGSRQVQF----HQGFGDLA--ILKPSNKVLQVSIGPGLPKNSRPTRRNTVTSRG-YPGGTKNNYPMRAAPAPPGCHQN--------GVIRNQFVPPPHAFGNQRSNQKSLYTSMARPPL---PRQQSTGSDRLSQTPESLDFLKVPDQGVAGVRRQTSSRPPPAGGRPKPQPKPKPQVPQCKALYAYDAQDTDELSFNANDIIDIIKEDPSGWWTGRLRGKQGLFPNNYVTKI 1107
BLAST of Myosin IE vs. Ensembl Mouse
Match: Myo1f (myosin IF [Source:MGI Symbol;Acc:MGI:107711]) HSP 1 Score: 975.696 bits (2521), Expect = 0.000e+0 Identity = 469/774 (60.59%), Postives = 594/774 (76.74%), Query Frame = 3
Query: 63 KNMHHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRM-NKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELK-NPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFK 2378
K HWQS K S DD+VLLP+I++D+I NL+KRFMDD I+TYIG+VLI+VNPFK++ FT +EI +YQGAA YENPPHIYA+ DNM+RNM+ID E+QCVIISGESGAGKTV+AK+IM YISKVSGG +V+ +K+IIL+SNPLLEAFGNAKTVRNNNSSRFGKY EIQF RGGEP GGKIS FLLEKSRVV+QN+NERNFHI+YQL+EG ++ ++ G+ TPDYY YLNQS YKV+ TDD+S+F T+ AM+V+G+ Q +L +VA +LHLGN+ F E A + L FP YLLG++ L K+ SR+M + + ++I + N +QA RDAL+K LY+R+FD++V+ IN AM ++ +IG+LDIYGFEIF KNGFEQFCIN+VNEKLQQIFIELTLKAEQ+EYVQEG++WTP+ YFNNK+VCDLIE K +PPG+ S+LDDVCAT D + K+ + +H++S S GF I HYAGKVSY+ GFCERNRD L D+IE+MQ S F+ LFPE + K R + T GS+I+KQANDLV L KC PHYIRCIKPNETK+ RDWE RV QV YLGLRENI VRRAG+AYRR F KF+QRYAIL+ ETWP+W GD ++G+QHL++ ++ Q+Q+G TK+F+K+PESLFLLEE RERKF+ +A+ IQ +R+ A + Y ++RE A+++ NKKERR +S+NRNF+GDYL L+E P+LR + KRE+V+F+ V KYDRRFK
Sbjct: 4 KERFHWQSHNVKQSGVDDMVLLPQITEDAIVSNLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGGDKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQQQNLGLMTPDYYYYLNQSDTYKVEGTDDRSDFSETLSAMQVIGIPTSVQQLVLQLVAGILHLGNISFCEEGNYARVESVDLLAFPAYLLGIDSGRLQEKLTSRKMDSKWGGRSESIDVTLNVEQAAYTRDALAKGLYARLFDFLVEAINRAMQKPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIEYFNNKIVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKLQAAVGTHEHFNSWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQSSDQDFLRMLFPEKLNIDKKGRPS-TAGSKIKKQANDLVSTLKKCTPHYIRCIKPNETKRPRDWEESRVKHQVEYLGLRENIRVRRAGFAYRRQFSKFLQRYAILTPETWPRWRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEMRERKFDGFARTIQKAWRRHVAVRKYEEMREEASNILLNKKERRRNSINRNFVGDYLGLEERPELRQFLAKRERVDFADSVTKYDRRFK 776
BLAST of Myosin IE vs. Ensembl Mouse
Match: Myo1b (myosin IB [Source:MGI Symbol;Acc:MGI:107752]) HSP 1 Score: 565.844 bits (1457), Expect = 0.000e+0 Identity = 300/719 (41.72%), Postives = 449/719 (62.45%), Query Frame = 3
Query: 114 DLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTP-DYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLF-----IEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRMNKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKIN--VAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSS---------------HSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLR 2201
D+VLL +++++ +NLKKRF + IYTYIG+V+I+VNP++ L I++ +++ Y+ YE PHI+A++D +R++ + QC++I+GESGAGKT ++K +M Y++ V G V Q+KE +L+SNP+LEAFGNAKTVRN+NSSRFGKY++I+FD G+P+GG IS +LLEKSRVV Q + ERNFH+FYQL+ G +++ + Y+YL+ KV+ DD + F+ +AM+++G E ++L +VAAVL LGN+ F + G +++ KDK L+ C L +++ L + R + K++ + N QA+ ARDAL+K LYSR+F ++V++IN + + +G+LDIYGFEIF N FEQF INY NEKLQQIFIELTLK EQ+EY++E ++WT ++YFNN ++CDLIE N G+ ++LD+ C VTD F+ K++ H+ S HS F I HYAGKV Y+ EGF ++N D L D+ + M K+ + I LFPE N + T GS+ + L+ L P+YIRCIKPN+ K A + V Q+ YLGL EN+ VRRAGYA+R+ +E ++RY +L K+TWP W G + G++ L +I + G++K+FI++P +LF LE+ R+++ A +IQ +R H+L ++
Sbjct: 25 DMVLLEPLNEETFIDNLKKRFDHNEIYTYIGSVVISVNPYRSLPIYSPEKVEDYRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQPRGERNFHVFYQLLSGASEELLYKLKLERDFSRYNYLSLDSA-KVNGVDDAANFRTVRNAMQIVGFLDHEAEAVLEVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELTSIDQVVLERAFSFRTVEA---KQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREDIEWTHIDYFNNAIICDLIE-NNTNGILAMLDEECLRPGTVTDET---FLEKLNQVCATHQHFESRMSKCSRFLNDTTLPHSC-FRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKAGHSLIKSLFPEGNPAKVNLKRPPTAGSQFKASVATLMRNLQTKNPNYIRCIKPNDKKAAHIFNESLVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFNELEIPVEEHSFGRSKIFIRNPRTLFQLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMK 734
BLAST of Myosin IE vs. Ensembl Mouse
Match: Myo1b (myosin IB [Source:MGI Symbol;Acc:MGI:107752]) HSP 1 Score: 565.844 bits (1457), Expect = 0.000e+0 Identity = 300/719 (41.72%), Postives = 449/719 (62.45%), Query Frame = 3
Query: 114 DLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTP-DYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLF-----IEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRMNKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKIN--VAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSS---------------HSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLR 2201
D+VLL +++++ +NLKKRF + IYTYIG+V+I+VNP++ L I++ +++ Y+ YE PHI+A++D +R++ + QC++I+GESGAGKT ++K +M Y++ V G V Q+KE +L+SNP+LEAFGNAKTVRN+NSSRFGKY++I+FD G+P+GG IS +LLEKSRVV Q + ERNFH+FYQL+ G +++ + Y+YL+ KV+ DD + F+ +AM+++G E ++L +VAAVL LGN+ F + G +++ KDK L+ C L +++ L + R + K++ + N QA+ ARDAL+K LYSR+F ++V++IN + + +G+LDIYGFEIF N FEQF INY NEKLQQIFIELTLK EQ+EY++E ++WT ++YFNN ++CDLIE N G+ ++LD+ C VTD F+ K++ H+ S HS F I HYAGKV Y+ EGF ++N D L D+ + M K+ + I LFPE N + T GS+ + L+ L P+YIRCIKPN+ K A + V Q+ YLGL EN+ VRRAGYA+R+ +E ++RY +L K+TWP W G + G++ L +I + G++K+FI++P +LF LE+ R+++ A +IQ +R H+L ++
Sbjct: 19 DMVLLEPLNEETFIDNLKKRFDHNEIYTYIGSVVISVNPYRSLPIYSPEKVEDYRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQPRGERNFHVFYQLLSGASEELLYKLKLERDFSRYNYLSLDSA-KVNGVDDAANFRTVRNAMQIVGFLDHEAEAVLEVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELTSIDQVVLERAFSFRTVE---AKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREDIEWTHIDYFNNAIICDLIE-NNTNGILAMLDEECLRPGTVTDET---FLEKLNQVCATHQHFESRMSKCSRFLNDTTLPHSC-FRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKAGHSLIKSLFPEGNPAKVNLKRPPTAGSQFKASVATLMRNLQTKNPNYIRCIKPNDKKAAHIFNESLVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFNELEIPVEEHSFGRSKIFIRNPRTLFQLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMK 728
BLAST of Myosin IE vs. UniProt/SwissProt
Match: sp|Q12965|MYO1E_HUMAN (Unconventional myosin-Ie OS=Homo sapiens OX=9606 GN=MYO1E PE=1 SV=2) HSP 1 Score: 1147.88 bits (2968), Expect = 0.000e+0 Identity = 591/1119 (52.82%), Postives = 782/1119 (69.88%), Query Frame = 3
Query: 72 HHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRM-NKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELK-NPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPEG---FQGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTKPGNRDLRAIQAILPTLEKSGIRIKRADTKKVINQTQSFMKSNQQIDRNSTDKLPNLPQSGKAKFPSMSQMRMTPVMGVNPRQSQITDEELVKSV------------SKNSKRESNITDXXXXXXXXXXXXXXXXVNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 3377
+HWQS K+S DD+VLL KI+++SI ENLKKR+MDD I+TYIG+VLI+VNPFK++ F +KEI MYQGAA YENPPHIYA+ADNM+RNM+ID E+QCVIISGESGAGKTV+AK+IM YIS+VSGG +V+ +K+IIL+SNPLLEAFGNAKTVRNNNSSRFGKY EIQF GGEP GGKIS FLLEKSRVV++N ER+FHIFYQLIEG + + GIT+ DYY YL+ SG YKVDD DD+ EF+ T+HAM V+G+ +EQ +L IVA +LHLGN+ F E A + + L FP YLLG+ + L K+ SR+M + K ++I + N +QA RDAL+KAL++R+FD++VD IN AM + ++ NIG+LDIYGFEIF KNGFEQFCIN+VNEKLQQIFIELTLKAEQ+EYVQEG++WTP+ YFNNK+VCDLIE K NPPG+ SILDDVCAT V + D + K+ + +H++S + GF I HYAGKVSY+ +GFCERNRD L +D+IE+MQ S PFI LFPEN+ K R T T GS+I+KQANDLV L KC PHYIRCIKPNETKK RDWE RV QV YLGL+ENI VRRAGYAYRR F+KF+QRYAIL+K TWP W G+ K+G+ HL+++ +++ Q+Q+G++K+FIK PESLFLLEE RERK++ YA+VIQ +R+ A K Y+++RE A+DL NKKERR +S+NRNFIGDY+ ++E+P+L+ +GKREK++F+ V KYDRRFK + RDL+LT K +YLIGR+K+KQG KG EV+KRK++I + ++LS D+ ++ +EYDS++E FKTEF+ +L+KRY E T + L LKF + +K E + G S+++ F D+A V + + VS+ GLP N++P R+ + + ++ A +Q + RN P+ P S ++ S+ P + PRQ + + + ++ + +R++ +P +P V + +ALYAY+A DTDELS DII++++ED GWWTG++ + GL P+NYV KI
Sbjct: 9 YHWQSHNVKHSGVDDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMYQGAAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVSGGGTKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASAEQKHSLGITSMDYYYYLSLSGSYKVDDIDDRREFQETLHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKEVGNYAAVESEEFLAFPAYLLGINQDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSINKAMEKDHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQIGSHEHFNSWNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELPFIKSLFPENLQADKKGRPT-TAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPRDWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPSWQGEEKQGVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWRKFVARKKYVQMREEASDLLLNKKERRRNSINRNFIGDYIGMEEHPELQQFVGKREKIDFADTVTKYDRRFKGVKRDLLLTPKCLYLIGREKVKQGPDKGLVKEVLKRKIEIERILSVSLSTMQDDIFILH-EQEYDSLLESVFKTEFLSLLAKRYEEKTQKQLPLKFSNTLELKLKKENWGPWSAGGSRQVQF----HQGFGDLA--VLKPSNKVLQVSIGPGLPKNSRPTRRNTTQNTGYSSGTQNANYPVRAAPPPPGYHQN--------GVIRNQYVPYPHAPGSQRSNQKSLYTSMARPPL---PRQQSTSSDRVSQTPESLDFLKVPDQGAAGVRRQTTSRPPPAGGRPKPQPKPKPQVPQCKALYAYDAQDTDELSFNANDIIDIIKEDPSGWWTGRLRGKQGLFPNNYVTKI 1108
BLAST of Myosin IE vs. UniProt/SwissProt
Match: sp|E9Q634|MYO1E_MOUSE (Unconventional myosin-Ie OS=Mus musculus OX=10090 GN=Myo1e PE=1 SV=1) HSP 1 Score: 1135.17 bits (2935), Expect = 0.000e+0 Identity = 586/1119 (52.37%), Postives = 781/1119 (69.79%), Query Frame = 3
Query: 72 HHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRM-NKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELK-NPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPEG---FQGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTKPGNRDLRAIQAILPTLEKSGIRIKRADTKKVINQTQSFMKSNQQIDRNSTDKLPNLPQSGKAKFPSMSQMRMTPVMGVNPRQSQITDEELVKSVSK------------NSKRESNITDXXXXXXXXXXXXXXXXVNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 3377
+HWQS K+S DD+VLL KI++ SI ENLKKR+MDD I+TYIG+VLI+VNPFK++ F +KE+ MYQGAA YENPPHIYA+AD+M+RNM+ID E+QCVIISGESGAGKTV+AK+IM Y+S+VSGG +V+ +K+IIL+SNPLLEAFGNAKTVRNNNSSRFGKY EIQF GGEP GGKIS FLLEKSRVV++N ER+FHIFYQLIEG + ++ GIT+ DYY YL+ SG YKVDD DDK +F+ T+HAM V+G+ +EQ +L IVA +LHLGN+ F E A + + L FP YLLG+ + L K+ SR+M + K ++I + N +QA RDAL+KAL++R+FD++VD IN AM + ++ NIG+LDIYGFEIF KNGFEQFCIN+VNEKLQQIFIELTLKAEQ+EYVQEG++WTP+ YFNNK+VCDLIE K NPPG+ SILDDVCAT V + D + K+ + +H++S + GF I HYAGKVSY+ +GFCERNRD L +D+IE+MQ S PFI LFPEN+ K R T T GS+I+KQANDLV L KC PHYIRCIKPNETKK +DWE RV QV YLGL+ENI VRRAGYAYRR F+KF+QRYAIL+K TWP W GD K+G+ HL+++ +++ Q+Q+G++K+FIK PESLFLLEE RERK++ YA+VIQ +R+ A K Y+++RE A+DL NKKERR +S+NRNFIGDY+ ++E P+L+ +GKREK++F+ V KYDRRFK + RDL+LT K +YLIGR+K+KQG KG EV+KR++++ + ++LS D+ ++ +EYDS++E FKTEF+ +L+KRY E T + L LKF + +K E + G S+++ F D+A + + + VS+ GLP N++P R+ + P K+ ++ A +Q + RN P+ + ++ S+ P + PRQ + L ++ +R+++ +P +P V + +ALYAY+A DTDELS DII++++ED GWWTG++ + GL P+NYV KI
Sbjct: 9 YHWQSHNVKHSGVDDMVLLSKITESSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEVEMYQGAAQYENPPHIYALADSMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYVSRVSGGGPKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASPEQKQSLGITSMDYYYYLSLSGSYKVDDIDDKRDFQETLHAMNVIGIFSEEQTLVLQIVAGILHLGNISFKEVGNYAAVESEEFLAFPAYLLGINQDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSINKAMEKDHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIEYFNNKIVCDLIESKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQIGSHEHFNSWNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELPFIKSLFPENLQADKKGRPT-TAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPKDWEESRVKHQVEYLGLKENIRVRRAGYAYRRVFQKFLQRYAILTKATWPVWRGDEKQGVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKTWRKFVARKKYVQMREEASDLLLNKKERRRNSINRNFIGDYIGMEERPELQQFVGKREKIDFADTVTKYDRRFKGVKRDLLLTPKCLYLIGREKVKQGPDKGVVKEVLKRRIEVERILSVSLSTMQDDIFILH-EQEYDSLLESVFKTEFLSLLAKRYEEKTQKQLPLKFSNTLELKLKKENWGPWSAGGSRQVQF----HQGFGDLA--ILKPSNKVLQVSIGPGLPKNSRPTRRNTVTSRG-YPGGTKNNYPMRAAPAPPGCHQN--------GVIRNQFVPPPHAFGNQRSNQKSLYTSMARPPL---PRQQSTGSDRLSQTPESLDFLKVPDQGVAGVRRQTSSRPPPAGGRPKPQPKPKPQVPQCKALYAYDAQDTDELSFNANDIIDIIKEDPSGWWTGRLRGKQGLFPNNYVTKI 1107
BLAST of Myosin IE vs. UniProt/SwissProt
Match: sp|Q63356|MYO1E_RAT (Unconventional myosin-Ie OS=Rattus norvegicus OX=10116 GN=Myo1e PE=1 SV=1) HSP 1 Score: 1134.4 bits (2933), Expect = 0.000e+0 Identity = 590/1123 (52.54%), Postives = 780/1123 (69.46%), Query Frame = 3
Query: 72 HHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRM-NKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELK-NPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPEG---FQGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTKPGNRD----------------LRAIQAILPTLEKSGIRIKRADTKKVINQTQSFMKSNQQIDRNSTDKLPNLPQSGKAKFPSMSQMRMTPVMGVNPRQSQITDEELVKSVSKNSKRESNITDXXXXXXXXXXXXXXXXVNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 3377
+HWQS K+S DD+VLL KI++ SI ENLKKR+MDD I+TYIG+VLI+VNPFK++ F +KEI MYQGAA YENPPHIYA+AD+M+RNM+ID E+QCVIISGESGAGKTV+AK+IM Y+S+VSGG +V+ +K+IIL+SNPLLEAFGNAKTVRNNNSSRFGKY EIQF GGEP GGKIS FLLEKSRVV++N ER+FHIFYQLIEG + ++ GIT+ DYY YL+ SG YKVDD DDK +F+ T+HAM V+G+ +EQ +L IVA +LHLGN+ F E A + + L FP YLLG+ + L K+ SR+M + K ++I + N +QA RDAL+KAL++R+FD++VD IN AM + ++ NIG+LDIYGFEIF KNGFEQFCIN+VNEKLQQIFIELTLKAEQ+EYVQEG++WTP+ YFNNK+VCDLIE K NPPG+ SILDDVCAT V + D + K+ + +H++S + GF I HYAGKVSY+ +GFCERNRD L +D+IE+MQ S PFI LFPEN+ K R T T GS+I+KQANDLV L KC PHYIRCIKPNETKK +DWE RV QV YLGL+ENI VRRAGYAYRR F+KF+QRYAIL+K TWP W GD K+G+ HL+++ +++ Q+Q+G++K+FIK PESLFLLEE RERK++ YA+VIQ +R+ A K Y+++RE A+DL NKKERR +S+NRNFIGDY+ ++E+P+L+ +GKREK++F+ V KYDRRFK + RDL+LT K +YLIGR+K+KQG KG EV+KRK+++ + ++LS D+ ++ +EYDS++E FKTEF+ +L+KRY E T + L LKF + +K E + G S+++ F + S + + VS+ GLP N +P R+ +RA A P ++G+ + + Q +SNQ+ S + P LP+ +SQ + P Q + +R++ +P +P V + +ALYAY+A DTDELS D+I++++ED GWWTG++ + GL P+NYV KI
Sbjct: 9 YHWQSHNVKHSGVDDMVLLSKITESSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMYQGAAQYENPPHIYALADSMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYVSRVSGGGPKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASPEQKQSLGITSMDYYYYLSLSGSYKVDDIDDKRDFQETLHAMNVIGIFSEEQTLVLQIVAGILHLGNINFKEVGNYAAVESEEFLAFPAYLLGINQDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSINKAMEKDHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIEYFNNKIVCDLIESKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQIGSHEHFNSWNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELPFIKSLFPENLQADKKGRPT-TAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPKDWEESRVKHQVEYLGLKENIRVRRAGYAYRRVFQKFLQRYAILTKATWPVWRGDEKQGVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKTWRKFVARKKYVQMREDASDLLLNKKERRRNSINRNFIGDYIGMEEHPELQQFVGKREKIDFADIVTKYDRRFKGVKRDLLLTPKCLYLIGREKVKQGPDKGLVKEVLKRKIEVERILSVSLSTMQDDIFILH-EQEYDSLLESVFKTEFLSLLTKRYEEKTQKQLPLKFSNTLELKLKKENWGPWSAGGSRQVQFYQGFGDLAILKPS------NKVLQVSIGPGLPKNARPTRRNTVSSRGYSGGTNNNYPMRAAPAP-PGCHRNGLTRNQFVHPPRASGNQ---RSNQKSLYTSMAR-PPLPRQQSTGSDRLSQTPESLDFLKVPDQG-----------AAGVRRQTTSRPPPAGGRPKPQPKPKPQVPQCKALYAYDAQDTDELSFNANDVIDIIKEDPSGWWTGRLRGKQGLFPNNYVTKI 1107
BLAST of Myosin IE vs. UniProt/SwissProt
Match: sp|O00160|MYO1F_HUMAN (Unconventional myosin-If OS=Homo sapiens OX=9606 GN=MYO1F PE=1 SV=3) HSP 1 Score: 1134.01 bits (2932), Expect = 0.000e+0 Identity = 581/1114 (52.15%), Postives = 765/1114 (68.67%), Query Frame = 3
Query: 63 KNMHHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRM-NKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELK-NPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPEGFQGGSSKKITFTVATQNKTCDVAS-KVQGLLSTAMTVSVPRGLPSNTKPGNRDL---RAIQAILPTLEKSGIRIKRADTKKVINQTQSFMKSNQQIDRNSTDKLPNLPQS---GKAKFPSMSQMRMTPVMGVNPRQSQITDEELVKSVSKNSKRESNITDXXXXXXXXXXXXXXXXVNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 3377
K HWQS K S DD+VLLP+I++D+I NL+KRFMDD I+TYIG+VLI+VNPFK++ FT +EI +YQGAA YENPPHIYA+ DNM+RNM+ID E+QCVIISGESGAGKTV+AK+IM YISKVSGG +V+ +K+IIL+SNPLLEAFGNAKTVRNNNSSRFGKY EIQF RGGEP GGKIS FLLEKSRVV+QN+NERNFHI+YQL+EG ++ R+ G+ TPDYY YLNQS Y+VD TDD+S+F T+ AM+V+G+ Q +L +VA +LHLGN+ F E A + L FP YLLG++ L K+ SR+M R + ++I + N +QA RDAL+K LY+R+FD++V+ IN AM ++ +IG+LDIYGFEIF KNGFEQFCIN+VNEKLQQIFIELTLKAEQ+EYVQEG++WTP+ YFNNKVVCDLIE K +PPG+ S+LDDVCAT D + K+ + +H++S S GF I HYAGKVSY+ GFCERNRD L D+IE+MQ S F+ LFPE + K R + T GS+I+KQANDLV L +C PHYIRCIKPNETK+ RDWE +RV QV YLGL+ENI VRRAG+AYRR F KF+QRYAIL+ ETWP+W GD ++G+QHL++ ++ Q+Q+G TK+F+K+PESLFLLEE RERKF+ +A+ IQ +R+ A + Y ++RE A+++ NKKERR +S+NRNF+GDYL L+E P+LR +GKRE+V+F+ V KYDRRFK + RDLILT K +Y+IGR+K+K+G +KGQ EV+K+K+DI AL ++LS D+F ++ DS +E FKTEF+ +L KR+ E T R L L F + F VK EG+ GG ++ +TF+ D+A KV G +TVSV GLP ++KP + + + ++ + + D V + + + T + P P S G ++ P R P N + D+ + +R+ ++ + P +P R ALY Y D DELS ++IE++ ED GWW G++ + GL P NYV+KI
Sbjct: 4 KERFHWQSHNVKQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGGEKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSDTYQVDGTDDRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESVDLLAFPAYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDFLVEAINRAMQKPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKLQAAVGTHEHFNSWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQAFLRMLFPEKLDGDKKGRPS-TAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPRDWEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRWRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQKAWRRHVAVRKYEEMREEASNILLNKKERRRNSINRNFVGDYLGLEERPELRQFLGKRERVDFADSVTKYDRRFKPIKRDLILTPKCVYVIGREKVKKGPEKGQVCEVLKKKVDIQALRGVSLSTRQDDFFILQ-EDAADSFLESVFKTEFVSLLCKRFEEATRRPLPLTFSDTLQFRVKKEGWGGGGTRSVTFSRG----FGDLAVLKVGG---RTLTVSVGDGLPKSSKPTRKGMAKGKPRRSSQAPTRAAPAPPRGMDRNGVPPSARGGPLPLEIMSGGGTHRPPRGPPSTSLGASRRP-----RARPPSEHNTEFLNVPDQGMA-----GMQRKRSVGQRPVPGVGRPKPQPRTHGPRCRALYQYVGQDVDELSFNVNEVIEILMEDPSGWWKGRLHGQEGLFPGNYVEKI 1098
BLAST of Myosin IE vs. UniProt/SwissProt
Match: sp|P70248|MYO1F_MOUSE (Unconventional myosin-If OS=Mus musculus OX=10090 GN=Myo1f PE=1 SV=1) HSP 1 Score: 1100.89 bits (2846), Expect = 0.000e+0 Identity = 575/1128 (50.98%), Postives = 757/1128 (67.11%), Query Frame = 3
Query: 63 KNMHHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRM-NKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELK-NPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPEGFQGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTKPGNRDL-------------RAIQAILPTLEKSGI----RIKRADTKKVINQTQSFMKSNQQIDRNSTDKLPNLPQSGKAKFPS--MSQMRMTPVMGVN--PRQSQITDEELVKSVSKNSKRESNITDXXXXXXXXXXXXXXXXVNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 3377
K HWQS K S DD+VLL +I++D+I NL KRFMDD I+TYIG+VLI+VNPFK++ FT +EI +YQGA YE PPHIYA+ DNM+RNM+ID E+QCVIISGESGAGKTV+AK+IM YISKVSGG +V+ +K+IIL+SNPLLEAFGNAKTVRNNNSSRFGKY EIQF RGGEP GGKIS FLLEKSRVV+QN+NERNFHI+YQL+EG ++ ++ GI + DYY YLNQS YKV+ TDD+S+F T+ AM+VMG + Q +L +VA +LHLGN+ F E A + SL FP YLLG++ L K+ SR+M + + ++I + N +QA RDAL+K LY+R+FD++V+ IN AM ++ +IG+LDIYGFEIF KNGFEQFCIN+VNEKLQQIFIELTLKAEQ+EYVQEG++WTP+ YFNNK+VCDLIE K +PPG+ S+LDDVCAT D + K+ + +H++S S GF I HYAGKVSY+ GFCERNRD L D+IE+MQ S F+ LFPE + K R + T GS+I+KQANDLV L KC PHYIRCIKPNETK+ RDWE RV QV YLGLRENI VRRAG+AYRR F KF+QRYAIL+ ETWP+W GD ++G+QHL++ ++ Q+Q+G TK+F+K+PESLFLLEE RERKF+ +A+ IQ +R+ A + Y ++RE A+++ NKKERR +S+NRNF+G+YL L+E P+LR + KRE+V+F+ V KYDRRFK + RDLILT K +Y+IG +K+K+G +KG EV+K+KLDI AL ++LS D+F ++ + D+ +E FKTEF+ +L KR+ E R L L F ++ F VK +G+ GG ++ +TF+ N A +T+S+ GLP N+KP + L RA+ L ++G R + T ++ Q F +++ I D + +A+ PS ++ P GV R+ I + S K R R ALY Y D DELS ++IE++ ED+ GWW G++ + GL P NYV+KI
Sbjct: 4 KERFHWQSHNVKQSGVDDMVLLSQITEDAIVRNLHKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLYQGAVQYEEPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGGDKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQQQNLGIMSQDYYYYLNQSDTYKVEGTDDRSDFSETLSAMQVMGFRQACQQLVLQLVAGILHLGNISFCEEGNYARVESVDSLAFPAYLLGIDSGRLQEKLTSRKMDSKWGGRSESIDVTLNVEQAAYTRDALAKGLYARLFDFLVEAINRAMQKPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIEYFNNKIVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKLQAAVGTHEHFNSWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQSSDQDFLRMLFPEKLNIDKKGRPS-TAGSKIKKQANDLVSTLKKCTPHYIRCIKPNETKRPRDWEESRVKHQVEYLGLRENIRVRRAGFAYRRQFSKFLQRYAILTPETWPRWRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEMRERKFDGFARTIQKAWRRHVAVRKYEEMREEASNILLNKKERRRNSINRNFVGNYLGLEERPELRQFLAKRERVDFADSVTKYDRRFKPIKRDLILTPKCVYVIGTEKVKRGPEKGLVREVLKKKLDIQALRGVSLSTRQDDFFILQ-EEAADTFLESIFKTEFVSLLCKRFEEAARRPLPLTFQDILQFRVKKKGWGGGGTRNVTFSAGQVNLAVLKAG------GKTLTISLGDGLPKNSKPTRKGLAQGKPRRSAQAPTRAVPWASQGLNRNGATLFPRGEGPYTLEIYIWPQEFPEASTAIHLQPQDA----SRRPRARPPSEHSTEFLNVPDQGVAGMQRKRSIGQRPVPASRPKPQPRTHG--------------------PRCRALYQYIGQDVDELSFNVNEVIEILIEDSSGWWKGRLHGQEGLFPGNYVEKI 1099
BLAST of Myosin IE vs. TrEMBL
Match: A0A3B3SJ72 (Myosin IEb OS=Paramormyrops kingsleyae OX=1676925 PE=3 SV=1) HSP 1 Score: 1194.87 bits (3090), Expect = 0.000e+0 Identity = 612/1121 (54.59%), Postives = 789/1121 (70.38%), Query Frame = 3
Query: 63 KNMHHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRM-NKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELK-NPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPEG---FQGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTKPGNRDLRAIQAILPTLEKSGIRIK-RADTKKVINQTQSFMKSNQQIDRNSTDKLPNLPQSGKAKFPSMSQMRMT----------PVMGVNPRQSQITDEELVKSVSKNSKRESNITDXXXXXXXXXXXXXXXXVNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 3377
K +HWQ++ K S DD+VLL KIS+D+IT+NLKKR+MDD I+TYIG VLI+VNPFK+L FT +E+ MYQGAA YENPPHIYA+ADNM+RNMMID E+ CVIISGESGAGKTV+AK+IM YISKVSGG +V+Q+K IIL+SNPLLEAFGNAKTVRNNNSSRFGKY EIQF RGGEP GGKIS FLLEKSRVV QNQ ERNFHI+YQL+EG K+ RE GITT DYY YLNQSG Y V+D DK EF +TM+AMEV+GL +D+Q ++L IVA +LHLGN+ F E A + L FP YLLG+ + L +K+ SR M + K + I + N +QA RDALSKALYSR+FDY+VD IN AM + +++NIG+LDIYGFEIF KNGFEQFCIN+VNEKLQQIFIELTLKAEQ+EYVQEG++WTP++YFNNKVVCDLIE K NPPG+ SILDDVCAT + D + K+ N +H++S + GF + HYAGKVSY+ GFCERNRD L +D+IE+MQ S FI DLFPEN+ K R T T GS+I+KQAN+LV L KC PHYIRCIKPNETK++RDWE RV QV YLGLRENI VRRAGYA+RR F KF+QRYAIL+KETWPKW GD K+G+ HL+++ +++ Q+Q+GK K+FIK PESLFLLEE RERK+N YA+VIQ +R+ A + Y+++RE A+DL NKKERR +S+NRNF+GDY+ D +P++R +G+RE+++F+ V KYDRRFK + RDLILT KF+YLIGR+K+KQG +KGQ EV+KR++++ + ++LS D+F++I ++YDSV+E FKTEF+ +L KRY E T + L +KF+ ++ F VK G F S+++ F ++ S S + V++ GLP N++P RD R Q + +SG + RA+T+ + +++ I + S+ + P LP+ + + Q R T V G++ R+S+ E K R + ALYAY+A DTDELS DII+++ ED GWW G++ + G+ P NYV+KI
Sbjct: 4 KERYHWQTQNVKVSGVDDMVLLSKISEDAITDNLKKRYMDDFIFTYIGPVLISVNPFKQLPYFTDREVEMYQGAAQYENPPHIYALADNMYRNMMIDSENHCVIISGESGAGKTVAAKYIMSYISKVSGGGPKVQQVKNIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRVVSQNQGERNFHIYYQLLEGASKEQRENLGITTSDYYLYLNQSGTYTVEDVSDKKEFSDTMNAMEVVGLTEDDQSAVLQIVAGILHLGNIAFREEGNYAVVESIDFLAFPAYLLGINQEGLKSKLTSRIMDSKWGGKSETISVTLNTEQAAFTRDALSKALYSRLFDYLVDAINKAMQKDREELNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIKWTPIDYFNNKVVCDLIESKLNPPGIMSILDDVCATMHAKGEGADQTLIQKLQMQIGNHEHFNSWNKGFVVHHYAGKVSYDVSGFCERNRDVLFIDIIELMQSSEYSFIKDLFPENLEAEKRGRPT-TAGSKIKKQANNLVQTLMKCTPHYIRCIKPNETKRSRDWEESRVKHQVEYLGLRENIRVRRAGYAFRRIFSKFLQRYAILTKETWPKWRGDEKQGVLHLLRSVNMDQDQYQLGKAKIFIKAPESLFLLEEMRERKYNGYARVIQKAWRKHVAVRKYVRMREEASDLLLNKKERRRNSINRNFVGDYIGTDNHPEIRRFVGRRERIDFADVVVKYDRRFKSVKRDLILTPKFLYLIGREKVKQGPEKGQIHEVLKRQIELDKVQTVSLSTVQDDFLIIH-EEQYDSVLECNFKTEFLSLLYKRYEEKTRKKLPIKFNNLLEFKVKKGGWGPFGAAGSRQVQFQTGQGDQAILKPS------SKLLLVTIGPGLPKNSRPTRRDKRKSQCLDNRQVQSGRNARPRAETRTRSGGNRPVSRAS-LIRQQSSMEQPTLPRLQGQRQSRVPQERPTNMDFMNVPDQGVAGLHRRRSKEYKPEPGAGRPKPRPRSP----------------------QCRALYAYDAQDTDELSFNAADIIDIINEDPSGWWLGRLRGKEGMFPGNYVEKI 1093
BLAST of Myosin IE vs. TrEMBL
Match: A0A5G3HU43 (Myosin IE OS=Xenopus tropicalis OX=8364 PE=3 SV=1) HSP 1 Score: 1186.02 bits (3067), Expect = 0.000e+0 Identity = 620/1123 (55.21%), Postives = 796/1123 (70.88%), Query Frame = 3
Query: 72 HHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRM-NKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELK-NPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPEGF----QGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTKPGNRDLR------------AIQAILPT--LEKSGIRIKRADTKKVINQTQSFMKSNQQIDRNSTDKLPNLPQSGKAKFPSMSQMRMTPVMGVNPRQSQITDEELVKSVS-KNSKRESNITDXXXXXXXXXXXXXXXXVNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 3377
+HWQS K+S DD+VLL KI++DSI +NLKKR+MDD I+TYIG VLI+VNPFK++ F KEI MYQGAA YENPPHIYA+ADNM+RNM+ID E+QCVIISGESGAGKTV+AK+IM YISKVSGG +V+ +K+IIL+SNPLLEAFGNAKTVRNNNSSRFGKY EIQF GGEP GGKIS FLLEKSRVV++N ER+FHIFYQLIEG KD RE GIT+ DYY+YLNQSG YKVDD +DK +F+ TMHAM V+G+ + Q ++ IVA VLHLGN+ F E A +++ L FP +LLG+ +S L K+ SR+M + K ++I + N +QA RDALSKAL+SR+FDY+VD IN AM + ++ NIG+LDIYGFEIF KNGFEQFCIN+VNEKLQQIFIELTLKAEQ+EYVQEG++WTP+ YFNNK+VCDLIE K NPPGV SILDDVCAT V + D + K+ + +H++S + GF I HYAGKVSY+ +GFCERNRD L +D+IE+MQ S PF+ LFPEN+ K R T T GS+I+KQANDLV L KC PHYIRCIKPNETKK RDWE RV QV YLGL+ENI VRRAGYAYRR F+KF+QRYAIL+KETWP W GD KKG+ HL+ + +++ Q+Q+GKTK+FIK PESLFLLEE RERK++ YA+ IQ +R+ A K Y+++RE+A+DLF NKKERR +S+NRNFIGDY+ +DE P+LR +GKREK++F+ V KYDRR K + RDLILT K +YLIGRDK+KQG +KG EV+K+K+D+ + ++LS D+F ++ +EYDS++E FKTEFI +LSK Y E T R L LKF+ +++ +K E + G S+++ F D+A V S + VS+ +GLP N++P R++ I+A P ++GI + + + + +N ++ +S D P LP+ ++T NP+Q Q D V ++R+S +P +P V + +ALYAY+A DTDELS DIIE+++ED+ GWWTGK+ + GL P+NYV KI
Sbjct: 9 YHWQSHNVKHSGVDDMVLLSKITEDSIVDNLKKRYMDDFIFTYIGPVLISVNPFKQMPYFGDKEIEMYQGAAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISKVSGGGPKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASKDQRESLGITSLDYYNYLNQSGSYKVDDINDKRDFQETMHAMNVIGISAEGQAMVMQIVAGVLHLGNIGFKEKGNYAAVENEEFLAFPAFLLGINQSRLKDKLTSRQMDSKWGGKSESINVTLNVEQACYTRDALSKALHSRVFDYLVDSINKAMKKDHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIEYFNNKIVCDLIENKVNPPGVMSILDDVCATMHAVGEGADQTLLQKLQMAVGTHEHFNSWNQGFIIHHYAGKVSYDVDGFCERNRDVLFMDLIELMQSSQQPFMQALFPENLQAEKKGRPT-TAGSKIKKQANDLVNTLMKCTPHYIRCIKPNETKKPRDWEESRVKHQVEYLGLKENIRVRRAGYAYRRVFKKFLQRYAILTKETWPSWKGDEKKGVLHLLHSVNMDSDQFQLGKTKIFIKAPESLFLLEEMRERKYDGYARSIQKAWRKYVARKKYVQMREQASDLFLNKKERRRNSINRNFIGDYIGMDERPELRQFVGKREKIDFADTVTKYDRRSKGVKRDLILTPKSVYLIGRDKMKQGPEKGLVKEVLKKKIDVERILSVSLSTMQDDFFILH-EQEYDSLLESLFKTEFISLLSKHYEEKTQRKLPLKFNNILDMKLKKENWGPWSGGAGSRQVQFIQG----FGDLA--VLKHSSKVLQVSIGQGLPKNSRPTRRNITNGRGNASKSKSYPIRAAPPPPGAHQNGIIMNPPFGHQPPKAARPY--NNSRMSHSSADH-PTLPR------------QVTGSSTRNPQQPQSLDFLRVPDQGVAGARRQSTNRPPPAGGRPKPQPKPKPHVPQCKALYAYDAQDTDELSFNANDIIEIIKEDSSGWWTGKLRGKQGLFPNNYVTKI 1108
BLAST of Myosin IE vs. TrEMBL
Match: M3ZWZ7 (Myosin IEa OS=Xiphophorus maculatus OX=8083 PE=3 SV=2) HSP 1 Score: 1182.93 bits (3059), Expect = 0.000e+0 Identity = 608/1117 (54.43%), Postives = 788/1117 (70.55%), Query Frame = 3
Query: 72 HHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRM-NKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPE--GFQ--GGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTKPGNRDLRAIQAILPTLEKSGIRIKRADTKKVINQTQSFMKSNQQIDRNSTDKLPNLPQS-GKAKFPSMSQMRMTPVM--GVNPRQSQITD-------EELVKSVSKNSKRESNITDXXXXXXXXXXXXXXXXVNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 3377
+HWQS K+S DD+VLL KIS+D I +NLKKR+MDD I+TYIG VLI+VNPFK++ F ++EI MYQGAA YENPPHIYA+ADNM+RNMMID E+QCVIISGESGAGKTV+AK+IM YISKVSGG RV+ +K+IIL+SNPLLEAFGNAKT+RNNNSSRFGKY EIQF GGEP GGKIS FLLEKSRVV++N ER+FHIFYQLIEG + ++ GIT+ DYYSYLNQSG YKVDD +D+SEF+ TM AM+V+G+ +++ +L IVA VLH+GN+ F E A + + L FP +LLG+++ L K+ SR+M + N +++I + N +QA RDALSKAL+SR+FDY+V+ IN AM + ++NIG+LDIYGFEIF KNGFEQFCIN+VNEKLQQIFIELTLKAEQ+EYVQEG++WTP++YFNNK+VCDLIE K+PPG+ ILDDVCAT V + D + K+ +H++S + GF I HYAGKVSY+ +GFCERNRD L D+IE+MQ S FI LFPEN+ K R T T GS+I+KQANDLV L KC PHYIRCIKPNETKK++DWE RV QV YLGL+ENI VRRAGYAYRR F KF+ RYAIL+KE+WP W GD K+G+ HL+++ +++ Q+Q+GKTK+FIK PESLFLLEE RERKF+ YA+ IQ +R+ A K Y+++RE A+DL N+K+RR HS+NRNFIGDYL +D+ P+LR + KREK++F+ V KYDRRFK + RDLILT K +YLIGR+K+KQG +KGQ EV+KRK+D+ + ++LS D+F+++ +EYDS++E FKTEFI +LS+R+ E T R L LKF+ + +K E GF GG S+++ F V Q + S S ++ VS+ GLP NT+P T+K +Q++S M N + + P +P S A S ++ +P G P + Q + EEL S + S T G +P +P V + +ALYAY+A DTDELS D+I++++ED GWWTG++ + GL P+NYV KI
Sbjct: 12 YHWQSHNVKHSGVDDMVLLSKISEDGIVDNLKKRYMDDYIFTYIGPVLISVNPFKQMPYFGEREIEMYQGAAQYENPPHIYALADNMYRNMMIDRENQCVIISGESGAGKTVAAKYIMGYISKVSGGGPRVQHVKDIILQSNPLLEAFGNAKTLRNNNSSRFGKYFEIQFSSGGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASGEQKKSLGITSLDYYSYLNQSGSYKVDDINDRSEFQETMQAMDVIGISAEDRSMVLQIVAGVLHVGNITFRESGNYAAVESEEFLAFPAFLLGIDQDRLKEKLTSRKMDSKWGNTKESIDVTLNVEQACYTRDALSKALHSRVFDYLVESINRAMVKDHQELNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIKWTPIDYFNNKIVCDLIESKSPPGIMCILDDVCATMHAVGEGADQTMLQKLRMQINTHEHFNSWNQGFIIHHYAGKVSYDADGFCERNRDVLFTDLIELMQSSDISFIRALFPENLNAEKKGRPT-TAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKSKDWEESRVKHQVEYLGLKENIRVRRAGYAYRRVFRKFLNRYAILTKESWPTWRGDEKQGVLHLLRSVNMDQDQFQLGKTKVFIKAPESLFLLEETRERKFDGYARAIQKAWRKYMARKKYVQMREEASDLLLNRKDRRRHSVNRNFIGDYLGMDDRPELRQFLAKREKIDFADKVTKYDRRFKGIKRDLILTPKSVYLIGREKVKQGPEKGQVTEVLKRKIDLEKILALSLSTLQDDFIILH-EQEYDSLLECIFKTEFISLLSRRFEEKTRRKLPLKFNNTLEMKLKKENWGFMSGGGGSRQVVF-VQGQGDVAVLKSS-----SKSLQVSIGPGLPKNTRP--------------------------TRKSFSQSRSNMSRNHHVPSRAAPGPPGIPVSFSAASLFFTSSIKSSPAFPPGSRPSERQPEEHQLHRQPEELAASQPEASALHQLHTPPPGGGRPKPVPKPKPQVPQCKALYAYDAQDTDELSFNTDDVIDIIKEDASGWWTGRLRGKQGLFPNNYVTKI 1094
BLAST of Myosin IE vs. TrEMBL
Match: A0A3Q1HE55 (Myosin IEa OS=Anabas testudineus OX=64144 PE=3 SV=1) HSP 1 Score: 1181.39 bits (3055), Expect = 0.000e+0 Identity = 604/1108 (54.51%), Postives = 787/1108 (71.03%), Query Frame = 3
Query: 72 HHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRM-NKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPE--GF-QGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTKPGNRDLRAIQAILPTLEKSGIRIKRADTKKVINQTQSFMKSNQQID-RNSTDKLPNLPQSGKAKFPSM-SQMRMTPVMGVNPRQSQITDEELVKSVSKNSKRESNITDXXXXXXXXXXXXXXXXVNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 3377
+HWQS K+S DD+VLL KI++D+I +NLKKR+MDD I+TYIG VLI+VNPFK++ F +KEI MYQGAA YENPPHIYA+ADNM+RNMMID E+QCVIISGESGAGKTV+AK+IM YIS+VSGG RV+ +K+IIL+SNPLLEAFGNAKTVRNNNSSRFGKY EIQF GGEP GGKIS FLLEKSRVV++N ER+FHIFYQLIEG + + GIT+ DYYSYLNQSG YKVDD +DKS+F+ TMHAM+V+G+ +E+ +L IVA VLHLGN+ F E A + + L FP +LLG++++ L K+ SR+M + N ++I + N +QA RDALSKAL+SR+FD++V+ IN AM + ++NIG+LDIYGFEIF KNGFEQFCIN+VNEKLQQIFIELTLKAEQ+EYVQEG++WTP+ YFNNK+VCDLIE KNPPG+ SILDDVCAT V + D + K+ +H++S + GF I HYAGKVSY+ EGFCERNRD L D+IE+MQ S FI LFP+N+ K R T T GS+I+KQANDLV L KC PHYIRCIKPNETKK++DWE RV QV YLGL+ENI VRRAGYAYRR F KF+ RYAIL+KE+WP W GD K+G+ HL+++ +++ Q+Q+G+TK+FIK PESLFLLEE RERKF+ YA+ IQ +R+ A K Y+++RE A+DL N+KERR HSLNRNF+GDYL +D+ P+LR +GKREK++F+ V KYDRRFK + RDLILT K +YLIGR+K+KQG +KGQ EV+KR++D+ + ++LS D+F+++ +EYDS++E FKTEFI +L++R+ E T R L LKF + +K E GF GG S+++ F + S S ++ V + GLP NT+P + + ++ + + I + A V +Q +N + RNS S A P + + + G + Q + ++ + + R+S G +P +P V + +ALYAY+A DTDELS DII++V+ED GWWTG++ + GL P+NYV KI
Sbjct: 9 YHWQSHNVKHSGVDDMVLLSKINEDAIVDNLKKRYMDDYIFTYIGPVLISVNPFKQMPYFGEKEIEMYQGAAQYENPPHIYALADNMYRNMMIDRENQCVIISGESGAGKTVAAKYIMSYISRVSGGGPRVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSSGGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASGEQKNSLGITSLDYYSYLNQSGSYKVDDINDKSDFQETMHAMDVIGISVEERAMVLQIVAGVLHLGNITFRESGNYAAVESEEFLAFPAFLLGIDQNRLKEKLTSRKMDSKWGNAVESIDVTLNVEQACYTRDALSKALHSRVFDFLVESINKAMVKDHQELNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIKWTPIEYFNNKIVCDLIESKNPPGIMSILDDVCATMHAVGEGADQTMLQKLRVQINTHEHFNSWNQGFIIHHYAGKVSYDAEGFCERNRDVLFNDLIELMQSSETAFIRALFPDNLNAEKKGRPT-TAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKSKDWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFRKFLNRYAILTKESWPTWRGDEKQGVLHLLRSVNMDQDQFQLGRTKIFIKAPESLFLLEETRERKFDGYARAIQKAWRKYVARKKYVQMREEASDLLLNRKERRRHSLNRNFVGDYLGMDDRPELRQFLGKREKIDFADKVTKYDRRFKGIKRDLILTPKSVYLIGREKVKQGPEKGQVTEVLKRRIDVEKILAVSLSTMQDDFMILH-EQEYDSLLECIFKTEFISLLARRFEEKTQRKLPLKFSNTLEMKLKKENWGFLSGGGSRQVMFVQGQGDMPVLKPS------SKSLQVIIGPGLPKNTRPNRKGITQGRSNMSRTHHN-IPSRAAPGPPVAHQNGGLTSANHVANQRNSQHHKQRHSSSSNATHPFLPNNINQLKERGGSRAQPDLACLKVPDQGAAGAHRQSASRPPPGGGRPKPAPKPKHLVPQCKALYAYDAQDTDELSFNAEDIIDIVKEDASGWWTGRLRGKQGLFPNNYVTKI 1107
BLAST of Myosin IE vs. TrEMBL
Match: Q6PFT4 (Zgc:64042 OS=Danio rerio OX=7955 GN=myo1eb PE=2 SV=1) HSP 1 Score: 1181.39 bits (3055), Expect = 0.000e+0 Identity = 609/1111 (54.82%), Postives = 781/1111 (70.30%), Query Frame = 3
Query: 63 KNMHHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRM-NKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELK-NPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPEG---FQGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTKPGNRDLRAIQAILPTLEKSGIRIKRADTKKVINQTQSFMKSNQQIDRNSTDKLPNLPQ-SGKAKFPSMSQMRMTPVMGVNPRQSQITDEELVKSVSKNSKRESNITDXXXXXXXXXXXXXXXXVNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 3377
K +HWQ++ K S DD+VLL KI++D+IT+NLKKR+MDD I+TYIG VLI+VNPFK+L FT +EI +YQGAA YENPPHIYA+ADNM+RNMMID E+QCVIISGESGAGKTV+AK+IM YISKVSGG +V+ +K+IIL+SNPLLEAFGNAKTVRNNNSSRFGKY EIQF RGGEP GGKIS FLLEKSRVV QN ERNFHI+YQL++G K+ RE G+TTPDYY YLNQS Y V+D +DK EF++TM+AM V+GL D Q S+L IVA +LHLGN+ F E A + + L FP YLLG+ + L +K+ SR M + K + I + N +QA RDALSKALYSR+FDY+VD IN AM + +++NIG+LDIYGFEIF KNGFEQFCIN+VNEKLQQIFIELTLKAEQ+EYVQEG+ WTP+ YFNNKVVCDLIE K NPPG+ SILDDVCAT + D + K+ +H++S + GF + HYAGKVSY+ GFCERNRD L D+IE+MQ S FI LFPEN+ K R T T GS+I+KQAN LV L KC PHYIRCIKPNETKK+RDWE RV QV YLGLRENI VRRAGYA+RR F+KF+ RYAIL++ETWP+W GD K+G+ HL+K+ +++ Q+Q+GKTK+FIK PESLFLLEE RERK+N YA+VIQ +R+ A + Y+++RE A+DL NKKERR++SLNRNF+GDY+ D +P++R +G+RE+++F+ V KYDRRFK + RDLILT KF+YLIGR+K+KQG +KGQ EV+KRK+++ + ++LS D+ ++ +YDSV++ FKTEF+ +L KR+ E T + L LKF+ ++ F VK G F S++I F + + S S +TVS+ GLP NT+P RD R + + +S + R K + + + ST P LP+ G + SQ+ MG ++ D+ + + SK + +P +P R +ALYAY+A DTDELS P DIIE++ ED GWW G++ + G+ P NYV+KI
Sbjct: 4 KEKYHWQTQNVKVSGVDDMVLLSKITEDAITDNLKKRYMDDYIFTYIGPVLISVNPFKQLPYFTDREIELYQGAAQYENPPHIYALADNMYRNMMIDSENQCVIISGESGAGKTVAAKYIMSYISKVSGGGPKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRVVSQNNGERNFHIYYQLLKGATKEQRENLGVTTPDYYFYLNQSDTYTVEDVNDKKEFEDTMNAMSVVGLSMDAQDSVLQIVAGILHLGNIAFREEGNYAVVESEDFLAFPSYLLGINQDGLKSKLTSRIMDSKWGGKTETISVTLNTEQASFTRDALSKALYSRLFDYLVDAINKAMQKDREELNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGISWTPIEYFNNKVVCDLIESKLNPPGIMSILDDVCATMHAKGEGADQTLLQKLQSQIGTHEHFNSWNKGFVVHHYAGKVSYDVSGFCERNRDVLFSDIIELMQSSEFAFIKGLFPENIEAEKRGRPT-TAGSKIKKQANTLVQTLMKCTPHYIRCIKPNETKKSRDWEESRVKHQVEYLGLRENIRVRRAGYAFRRIFKKFLHRYAILTRETWPQWRGDEKQGVLHLLKSVNMDSDQYQLGKTKIFIKAPESLFLLEEMRERKYNGYARVIQQAWRKHIAVRKYVRMREEASDLLLNKKERRKNSLNRNFVGDYIGTDNHPEIRQFVGRRERIDFADVVVKYDRRFKSVKRDLILTPKFLYLIGREKVKQGPEKGQIREVLKRKIEVEKIQSVSLSTLQDDIFILH-EDQYDSVLQSVFKTEFLSLLYKRFEEKTKKKLPLKFNNLLEFKVKKGGWGPFASAGSRQIQFQMGQGDDAVLKPS------SKILTVSIGSGLPKNTRPTRRDNRK-SSFMGNQNRSAGQYSREAPKSAGRGRGQPAVRHSLLRQQSTMDQPTLPRLQGSVRSQRESQVYTD--MGF----MKVPDQGVAGMHRRRSKEYKPLPG---SGRPKPSPKPVPRTPRCKALYAYDAQDTDELSFQPDDIIEILSEDPSGWWQGRLRGKEGMFPGNYVEKI 1096
BLAST of Myosin IE vs. Ensembl Cavefish
Match: myo1ea (unconventional myosin-Ie [Source:NCBI gene;Acc:103047085]) HSP 1 Score: 1171.76 bits (3030), Expect = 0.000e+0 Identity = 607/1127 (53.86%), Postives = 779/1127 (69.12%), Query Frame = 3
Query: 72 HHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRM-NKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELK-NPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPEG---FQGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTKPGNRDLRAIQAILPTLEKSGIRIKRADTKKVINQTQSFMKSNQQIDRNSTDKLPNLPQSGKAKFPSMSQMRMTPVMGVNPRQSQITDEELVKSVSKNSKRESNITDXXXXXXXXXXXXXXXXVNR--------------------VEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 3377
+HWQS K S DD+VLL KI++D+I ENLKKR+MDD I+TYIG VLI+VNPFK++ F KE+ MYQGAA YENPPHIYA+ADNM+RNMMID E+QCVIISGESGAGKTV+AK+IM YIS+VSGG RV+ +K+IIL+SNPLLEAFGNAKT+RNNNSSRFGKY EIQF GGEP GGKIS FLLEKSRVV++N ER+FHIFYQLIEG D + GIT+ DYYSYLNQSG YKVDD +DKS+F+ T+HAM+V+G+ ++++ +L IVA VLHLGN+ F E A + + L FP +LLG++++ L K+ SR+M R K ++I + N +QA RDALSKAL++R+FD++V+ IN AM + ++NIG+LDIYGFEIF KNGFEQFCIN+VNEKLQQIFIELTLKAEQDEYVQEG++WT + YFNNK+VCDLIE K NPPG+ SILDDVCAT + D + K+ N +H++S + GF I HYAGKVSY+ EGFCERNRD L D+IE+MQ S FI LFPEN+ K R T T GS+I+KQANDLV L KC PHYIRCIKPNETKK +DWE RV QV YLGL+ENI VRRAGYAYRR F KF+ RYAIL+KE+WP W GD K+G+ HL+++ +++ Q+Q+G+TKLFIK PESLFLLEE RERKF+ YA+ IQ +RQ A K Y+++RE A+DL NKKERR HSLNRNFIGDYL +D+ P+LR +GKREK++F+ V KYDRRFK + RDLIL+ K +YLIGR+K+KQG +KGQ EV+KR++D+ + ++LS D+F+++ +EYDS++E FKTEFI +LS+R+ E T R L LKF + +K E + G S+++ F + S + + VS+ GLP N++P +KS I R++ + + T + + + +N K N S + + SQ R P P +T +L S+ S ++ N+ D P + NR +ALYAY+A DTDELS DIIE+ ED GWWTG++ + GL P+NYV KI
Sbjct: 9 YHWQSHNVKQSGVDDMVLLTKINEDAIVENLKKRYMDDYIFTYIGPVLISVNPFKQMPYFGDKEVEMYQGAAQYENPPHIYALADNMYRNMMIDRENQCVIISGESGAGKTVAAKYIMGYISRVSGGGPRVQHVKDIILQSNPLLEAFGNAKTLRNNNSSRFGKYFEIQFSSGGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASGDQKSSLGITSLDYYSYLNQSGSYKVDDINDKSDFQETLHAMDVIGISREDRTMVLQIVAGVLHLGNISFREAGNYAAVESEEFLAFPAFLLGIDQARLKEKLTSRKMDGRWGGKSESIDVTLNVEQACFTRDALSKALHARVFDFLVESINKAMVKDHQELNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQDEYVQEGIRWTTIEYFNNKIVCDLIESKINPPGIMSILDDVCATMHAKGEGADQTMLQKLRMQINNHEHFNSWNQGFIIHHYAGKVSYDAEGFCERNRDVLFTDLIELMQSSEIAFIRALFPENLNADKKGRPT-TAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPKDWEESRVKHQVEYLGLKENIRVRRAGYAYRRVFRKFLNRYAILTKESWPTWRGDEKQGVLHLLRSVNMDQDQYQLGRTKLFIKAPESLFLLEETRERKFDGYARAIQKAWRQYVARKKYVQMREEASDLLLNKKERRRHSLNRNFIGDYLGMDDRPELRQFLGKREKIDFADKVTKYDRRFKGIKRDLILSPKCVYLIGREKVKQGPEKGQIKEVLKRRVDVEKIMAVSLSTLQDDFMILH-EQEYDSLLECVFKTEFISLLSRRFEEKTQRKLPLKFGNTLEMKLKKESWGPWSAGGSRQVQFIQGQGDAAVLRPS------NKMLQVSIGPGLPKNSRP--------------TKKSIIGQSRSNMSRPHHHTPTRVAPGPPVHQNGGLKHSNHAASQRNQQHQSSQ-RSAPANQSRPFLP-VTANQLKDRSSRQSAQQPNL-DCLRVPDQGAAGAHRQSTNRPAPGGGRPKPAPKPKPQVPQCKALYAYDAQDTDELSFNADDIIEITMEDASGWWTGRLRGKQGLFPNNYVTKI 1110
BLAST of Myosin IE vs. Ensembl Cavefish
Match: myo1ea (unconventional myosin-Ie [Source:NCBI gene;Acc:103047085]) HSP 1 Score: 1169.84 bits (3025), Expect = 0.000e+0 Identity = 607/1128 (53.81%), Postives = 780/1128 (69.15%), Query Frame = 3
Query: 72 HHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRM-NKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELK-NPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPEG---FQGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTKPGNR--------DLRAIQAILPTLEKSGIRIKRADTKKVINQTQSFMKSNQQIDRNST---DKLPNLPQSG----------KAKFPSMSQMRMTPVMGVNPRQSQITDEELVKSVSKNSKRESNITDXXXXXXXXXXXXXXXXVNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 3377
+HWQS K S DD+VLL KI++D+I ENLKKR+MDD I+TYIG VLI+VNPFK++ F KE+ MYQGAA YENPPHIYA+ADNM+RNMMID E+QCVIISGESGAGKTV+AK+IM YIS+VSGG RV+ +K+IIL+SNPLLEAFGNAKT+RNNNSSRFGKY EIQF GGEP GGKIS FLLEKSRVV++N ER+FHIFYQLIEG D + GIT+ DYYSYLNQSG YKVDD +DKS+F+ T+HAM+V+G+ ++++ +L IVA VLHLGN+ F E A + + L FP +LLG++++ L K+ SR+M R K ++I + N +QA RDALSKAL++R+FD++V+ IN AM + ++NIG+LDIYGFEIF KNGFEQFCIN+VNEKLQQIFIELTLKAEQDEYVQEG++WT + YFNNK+VCDLIE K NPPG+ SILDDVCAT + D + K+ N +H++S + GF I HYAGKVSY+ EGFCERNRD L D+IE+MQ S FI LFPEN+ K R T T GS+I+KQANDLV L KC PHYIRCIKPNETKK +DWE RV QV YLGL+ENI VRRAGYAYRR F KF+ RYAIL+KE+WP W GD K+G+ HL+++ +++ Q+Q+G+TKLFIK PESLFLLEE RERKF+ YA+ IQ +RQ A K Y+++RE A+DL NKKERR HSLNRNFIGDYL +D+ P+LR +GKREK++F+ V KYDRRFK + RDLIL+ K +YLIGR+K+KQG +KGQ EV+KR++D+ + ++LS D+F+++ +EYDS++E FKTEFI +LS+R+ E T R L LKF + +K E + G S+++ F + S + + VS+ GLP N++P + ++ PT G + + K N S Q + S P LP + A+ P++ +R+ P G Q + + + R+S G +P +P V + +ALYAY+A DTDELS DIIE+ ED GWWTG++ + GL P+NYV KI
Sbjct: 9 YHWQSHNVKQSGVDDMVLLTKINEDAIVENLKKRYMDDYIFTYIGPVLISVNPFKQMPYFGDKEVEMYQGAAQYENPPHIYALADNMYRNMMIDRENQCVIISGESGAGKTVAAKYIMGYISRVSGGGPRVQHVKDIILQSNPLLEAFGNAKTLRNNNSSRFGKYFEIQFSSGGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASGDQKSSLGITSLDYYSYLNQSGSYKVDDINDKSDFQETLHAMDVIGISREDRTMVLQIVAGVLHLGNISFREAGNYAAVESEEFLAFPAFLLGIDQARLKEKLTSRKMDGRWGGKSESIDVTLNVEQACFTRDALSKALHARVFDFLVESINKAMVKDHQELNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQDEYVQEGIRWTTIEYFNNKIVCDLIESKINPPGIMSILDDVCATMHAKGEGADQTMLQKLRMQINNHEHFNSWNQGFIIHHYAGKVSYDAEGFCERNRDVLFTDLIELMQSSEIAFIRALFPENLNADKKGRPT-TAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPKDWEESRVKHQVEYLGLKENIRVRRAGYAYRRVFRKFLNRYAILTKESWPTWRGDEKQGVLHLLRSVNMDQDQYQLGRTKLFIKAPESLFLLEETRERKFDGYARAIQKAWRQYVARKKYVQMREEASDLLLNKKERRRHSLNRNFIGDYLGMDDRPELRQFLGKREKIDFADKVTKYDRRFKGIKRDLILSPKCVYLIGREKVKQGPEKGQIKEVLKRRVDVEKIMAVSLSTLQDDFMILH-EQEYDSLLECVFKTEFISLLSRRFEEKTQRKLPLKFGNTLEMKLKKESWGPWSAGGSRQVQFIQGQGDAAVLRPS------NKMLQVSIGPGLPKNSRPTKKSIIGQSRSNMSRPHHHTPTRVAPGPPVHQNGGLKHSNHAASQRNQQHQSSQRSAPANQSRPFLPVTANQLKDRSSRQSAQQPNLDCLRV-PDQGAAGNQRPAANGGI-------AHRQSTNRPAPGGGRPKPAPKPKPQVPQCKALYAYDAQDTDELSFNADDIIEITMEDASGWWTGRLRGKQGLFPNNYVTKI 1120
BLAST of Myosin IE vs. Ensembl Cavefish
Match: myo1eb (myosin IEb [Source:ZFIN;Acc:ZDB-GENE-040426-1347]) HSP 1 Score: 1145.95 bits (2963), Expect = 0.000e+0 Identity = 597/1098 (54.37%), Postives = 763/1098 (69.49%), Query Frame = 3
Query: 111 DDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRM-NKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELK-NPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPEG---FQGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTKPGNRDLRAIQAILPTLEKSGIRIKRADTKKVINQT--QSFMKSNQQIDRNSTDKLPNLPQSGKAKFPSMSQMRMTPV--MGVNPRQSQITDEELVKSVSKNSKRESNITDXXXXXXXXXXXXXXXXVNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 3377
DD+VLL KI++D+IT+NLKKR+MDD I+TYIG VLI+VNPFK+L FT +E+ +YQGAA YENPPHIYA+ADNM+RNMMID E+QCVIISGESGAGKTV+AK+IM YISKVSGG +V+ +K+IIL+SNPLLEAFGNAKTVRNNNSSRFGKY EIQF RGGEP GGKIS FLLEKSRVV QN ERNFHI+YQL+ G K+ RE GITTPDYY Y+NQSG Y V+D DDK EF TM+AM V+GL +E+ ++L IVA +LHLGN+ F E A + + L FP YLLG+ + L K+ SR M + K ++I + N +QA RDALSKALY+R+FDY+VD IN AM + ++ NIG+LDIYGFEIF +NGFEQFCIN+VNEKLQQIFIELTLKAEQ+EYVQEG++WTP+ YFNNKVVCDLIE K NP G+ SILDDVCAT + D + K+ +H++S + GF + HYAGKVSY GFCERNRD L D+IE+MQ S FI DLFPEN+ K R T T G++I+KQAN LV L KC PHYIRCIKPNETKK+RDWE R QV YLGLRENI VRRAGYA+RR F+KF+ RYAIL+KETWP+W GD K+G+ HL+++ +++ Q+Q+GK+K+FIK PESLFLLEE RERK+N YA+VIQ +R+ A + Y+++RE A+D+ NKKERR +SLNRNF+GDY+ D P++R +G+RE++EF+ V KYDRRFK + RDLILT KF+YLIGR+K+KQG KGQ EV+KR++ + + ++LS D+F ++ ++YDSV+E FKTEF+ +L KRY E T R L LKF+ ++ F VK G F S+++ F +T S + S + VS+ GLP N++P + R + K+ + +S ++ +D+ P LP + P SQ + P MG + D+ + + SK + G P RP V + ALYAY+A DTDELS DII++V ED GWW G++ R G+ P NYV+KI
Sbjct: 3 DDMVLLSKINEDAITDNLKKRYMDDYIFTYIGPVLISVNPFKQLPYFTDREVELYQGAAQYENPPHIYALADNMYRNMMIDAENQCVIISGESGAGKTVAAKYIMSYISKVSGGGPKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRVVSQNHGERNFHIYYQLLTGASKEQRENLGITTPDYYVYMNQSGTYTVEDVDDKKEFSETMNAMSVIGLSVEEKDTVLQIVAGILHLGNITFREEGNYAVVESEDFLAFPSYLLGIAQDGLKKKLTSRVMDSKWGGKTESISVTLNTEQATFTRDALSKALYARLFDYLVDAINKAMQKDHEEFNIGVLDIYGFEIFQQNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIKWTPIEYFNNKVVCDLIESKMNPVGIMSILDDVCATMHAKGEGADQTLLQKLQAQISTHEHFNSWNKGFIVHHYAGKVSYNVSGFCERNRDVLFNDIIELMQSSEFGFIQDLFPENLEAEKKGRPT-TAGAKIKKQANTLVQTLMKCTPHYIRCIKPNETKKSRDWEESRAKHQVEYLGLRENIRVRRAGYAFRRVFKKFLHRYAILTKETWPQWRGDEKQGVLHLLRSVNMDSDQYQLGKSKIFIKAPESLFLLEEMRERKYNGYARVIQQAWRKHIAVRKYVRMREEASDILLNKKERRRNSLNRNFMGDYIGTDNRPEIRQFVGRRERIEFADVVLKYDRRFKTVKRDLILTSKFLYLIGREKVKQGPDKGQIREVLKRQIQVEKIQSVSLSTLQDDFFILH-EEQYDSVLESIFKTEFLSLLYKRYEEKTQRKLPLKFNNLLEFKVKKGGWGPFASSGSRQVQF------QTGQGESAILKPSSKTLIVSIGPGLPKNSRP------------------SVGTGRGEVKQGSQNSSRRSVLRQQASMDQ------PTLP---RFHGPRPSQKKNEPYTDMGF----MNVPDQGVAGLHRRLSK---EVKPLPGAGLPKPAPRPKPRVPQCRALYAYDAQDTDELSFNADDIIDIVNEDPSGWWVGRLRGREGMFPGNYVEKI 1058
BLAST of Myosin IE vs. Ensembl Cavefish
Match: myo1ea (unconventional myosin-Ie [Source:NCBI gene;Acc:103047085]) HSP 1 Score: 1111.67 bits (2874), Expect = 0.000e+0 Identity = 552/929 (59.42%), Postives = 699/929 (75.24%), Query Frame = 3
Query: 72 HHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRM-NKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELK-NPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPEG---FQGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTK 2843
+HWQS K S DD+VLL KI++D+I ENLKKR+MDD I+TYIG VLI+VNPFK++ F KE+ MYQGAA YENPPHIYA+ADNM+RNMMID E+QCVIISGESGAGKTV+AK+IM YIS+VSGG RV+ +K+IIL+SNPLLEAFGNAKT+RNNNSSRFGKY EIQF GGEP GGKIS FLLEKSRVV++N ER+FHIFYQLIEG D + GIT+ DYYSYLNQSG YKVDD +DKS+F+ T+HAM+V+G+ ++++ +L IVA VLHLGN+ F E A + + L FP +LLG++++ L K+ SR+M R K ++I + N +QA RDALSKAL++R+FD++V+ IN AM + ++NIG+LDIYGFEIF KNGFEQFCIN+VNEKLQQIFIELTLKAEQDEYVQEG++WT + YFNNK+VCDLIE K NPPG+ SILDDVCAT + D + K+ N +H++S + GF I HYAGKVSY+ EGFCERNRD L D+IE+MQ S FI LFPEN+ K R T T GS+I+KQANDLV L KC PHYIRCIKPNETKK +DWE RV QV YLGL+ENI VRRAGYAYRR F KF+ RYAIL+KE+WP W GD K+G+ HL+++ +++ Q+Q+G+TKLFIK PESLFLLEE RERKF+ YA+ IQ +RQ A K Y+++RE A+DL NKKERR HSLNRNFIGDYL +D+ P+LR +GKREK++F+ V KYDRRFK + RDLIL+ K +YLIGR+K+KQG +KGQ EV+KR++D+ + ++LS D+F+++ +EYDS++E FKTEFI +LS+R+ E T R L LKF + +K E + G S+++ F + S + + VS+ GLP N++
Sbjct: 19 YHWQSHNVKQSGVDDMVLLTKINEDAIVENLKKRYMDDYIFTYIGPVLISVNPFKQMPYFGDKEVEMYQGAAQYENPPHIYALADNMYRNMMIDRENQCVIISGESGAGKTVAAKYIMGYISRVSGGGPRVQHVKDIILQSNPLLEAFGNAKTLRNNNSSRFGKYFEIQFSSGGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASGDQKSSLGITSLDYYSYLNQSGSYKVDDINDKSDFQETLHAMDVIGISREDRTMVLQIVAGVLHLGNISFREAGNYAAVESEEFLAFPAFLLGIDQARLKEKLTSRKMDGRWGGKSESIDVTLNVEQACFTRDALSKALHARVFDFLVESINKAMVKDHQELNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQDEYVQEGIRWTTIEYFNNKIVCDLIESKINPPGIMSILDDVCATMHAKGEGADQTMLQKLRMQINNHEHFNSWNQGFIIHHYAGKVSYDAEGFCERNRDVLFTDLIELMQSSEIAFIRALFPENLNADKKGRPT-TAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPKDWEESRVKHQVEYLGLKENIRVRRAGYAYRRVFRKFLNRYAILTKESWPTWRGDEKQGVLHLLRSVNMDQDQYQLGRTKLFIKAPESLFLLEETRERKFDGYARAIQKAWRQYVARKKYVQMREEASDLLLNKKERRRHSLNRNFIGDYLGMDDRPELRQFLGKREKIDFADKVTKYDRRFKGIKRDLILSPKCVYLIGREKVKQGPEKGQIKEVLKRRVDVEKIMAVSLSTLQDDFMILH-EQEYDSLLECVFKTEFISLLSRRFEEKTQRKLPLKFGNTLEMKLKKESWGPWSAGGSRQVQFIQGQGDAAVLRPS------NKMLQVSIGPGLPKNSR 939 HSP 2 Score: 72.7886 bits (177), Expect = 2.010e-12 Identity = 32/56 (57.14%), Postives = 40/56 (71.43%), Query Frame = 3
Query: 3210 VNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 3377
V + +ALYAY+A DTDELS DIIE+ ED GWWTG++ + GL P+NYV KI
Sbjct: 980 VPQCKALYAYDAQDTDELSFNADDIIEITMEDASGWWTGRLRGKQGLFPNNYVTKI 1035
BLAST of Myosin IE vs. Ensembl Cavefish
Match: myo1f (myosin IF [Source:ZFIN;Acc:ZDB-GENE-081104-506]) HSP 1 Score: 1106.66 bits (2861), Expect = 0.000e+0 Identity = 539/925 (58.27%), Postives = 701/925 (75.78%), Query Frame = 3
Query: 72 HHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRM-NKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELK-NPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPEGFQGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNT 2840
+HWQS+ K S DD+VLL KI++D+I ENLKKR+MDD I+TYIG+VLI+VNPFK++ FT +EI +YQGAA YENPPHIYA+ DNM+RNMMID E+QCVIISGESGAGKTV+AK+IM YISKVSGG +V+ +K+IIL+SNPLLEAFGNAKTVRNNNSSRFGKY EIQF RGGEP GGKIS FLLEKSRVV QN+NERNFH+FYQ+IEG +E GI TPDYY++LNQSG YKVD T+D +F+ TM AM+V+G+ D Q L IVA +LHLGN+ FIE ++ + L FP YLLG+++S L K+ SR+M + K ++I + N++QA RDAL+KALY+R+FDY+V+ IN AM I++ +IG+LDIYGFEIF +NGFEQFCIN+VNEKLQQIFIELTLKAEQ+EYVQEG++WTP+ YFNNK+VCDLIE K NPPG+ S+LDDVCAT +D D+K + K+ + +H++S ++GF I HYAGKVSY+ GFCERNRD L D+IE+MQ S + FI LFPEN+ K R T T GS+I++QAN+LV L KC PHYIRCIKPNETK+ RDWE R QV YLGL+ENI VRRAG+A+RR F+KF+QRYAIL+ ET+P W G ++G+ HL+++ +++ Q+Q+G+TK+F+K+PESLFLLEE RERKF+ +A+ IQ +R+ A + Y ++RE A+D+ YN KERR +S+NRNF+GDYL ++E P+LR + KRE+V+F+ V KYDRRFK + RDLILT K IYLIGR+KIK+G +KGQ EV+KRKLDI ++ ++LS D+F V+ + +YDS++E FKTEF+ +L KR+ E T L L F+ + F +K EG+ GG ++ + F Q T V +T+S+ G+P +
Sbjct: 7 YHWQSQNVKQSGVDDMVLLSKITEDAIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFTDREIELYQGAAQYENPPHIYALTDNMYRNMMIDSENQCVIISGESGAGKTVAAKYIMGYISKVSGGGPKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRVVSQNENERNFHVFYQVIEGSSAQQKEALGIMTPDYYNFLNQSGTYKVDGTNDSKDFQETMEAMQVIGIPGDCQTQGLQIVAGILHLGNISFIEAGNYSQVESTDLLAFPAYLLGIDQSRLQEKLTSRKMDSKWGGKSESINVTLNQEQACYTRDALAKALYARLFDYLVEAINKAMQKPIEEFSIGVLDIYGFEIFQRNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIKWTPIEYFNNKIVCDLIENKLNPPGIMSVLDDVCATMHATSDGADDKLLQKLQAAVGTHEHFNSWNSGFVIHHYAGKVSYDINGFCERNRDVLFPDLIELMQSSEHSFIRSLFPENLNTDKKGRPT-TAGSKIKRQANELVDTLMKCTPHYIRCIKPNETKRPRDWEESRAKHQVEYLGLKENIRVRRAGFAFRRIFQKFLQRYAILTPETYPYWRGQEQQGVLHLLRSVNMDTDQYQLGRTKVFVKNPESLFLLEEMRERKFDTFARTIQKAWRKYIARRKYEQMREEASDILYNSKERRRNSINRNFVGDYLGMEERPELRQFLAKRERVDFADSVNKYDRRFKSIKRDLILTPKGIYLIGREKIKKGPEKGQIKEVLKRKLDIGSIRSVSLSTRQDDFFVLHEA-QYDSLLESMFKTEFLSLLCKRFEEQTKSKLPLSFNDRLEFRLKKEGWGGGGTRTLMFQRG-QGDTVQVKPG-----GKTLTISIGDGMPKTS 923
BLAST of Myosin IE vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001434.1 (pep scaffold:Pmarinus_7.0:GL493165:42961:106906:1 gene:ENSPMAG00000001264.1 transcript:ENSPMAT00000001434.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 1155.97 bits (2989), Expect = 0.000e+0 Identity = 597/1124 (53.11%), Postives = 782/1124 (69.57%), Query Frame = 3
Query: 63 KNMHHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRM-NKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELK-NPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPEGFQGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTKPGNRDL---------RAIQAILPTLEKSGIRIKRADTKKVINQTQSFMKSNQQIDRNSTDKLPNLPQSG-KAKFPSMSQMRMTPVMGVNPRQSQITDEELVKSVSKNS-----KRESNITDXXXXXXXXXXXXXXXXVNRVEALYAYEATDTDELSIYPGDIIELVRE--DNEGWWTGKIGNRTGLIPSNYVKKI 3377
K +HWQS K+S DD+VLLPKIS+D+I +NLKKR+MDD I+TYIG VLI+VNPFK++ FT KEI +YQGAA YENPPHIYA+ADNM+RNM+ID E+QCVIISGESGAGKTV+AK+IM Y+SKVSGG +V+ +K+IIL SNPLLEAFGNAKTVRNNNSSRFGKY EIQF RGGEP GGKIS FLLEKSRVV QN ERNFHI+YQL E D +E GITTPDYY YLNQSG YKVDD DD+ +F+ TM AM V+G+ + Q +L IVA +LHLGN+ F E A ++ L FP +LLG+E++ L K+ SR+M + K + I + N +QA RDAL+KALY+R+FDY+V+ IN A+ + ++ N+G+LDIYGFEIF KNGFEQFCIN+VNEKLQQIFIELTLKAEQ+EYVQEG++WTP++YFNNK+VCDLIE K NPPG+ S+LDDVCAT + D + K+ + +H++S + GF + HYAGKVSY+ EGFCERNRD L D+IE+MQ S + FI LFPEN+ K R T TV S+I+KQANDLV L KC PHYIRCIKPNETK+ RDWE RV Q YLGLRENI VRRAGYAYRR F+KF+QRYAIL++ETWP+W G+ +KG+++L++T +++ Q+Q+G+TK+F+K PESLFLLEE RERK++ YA+ IQ +R+ A K Y+K+RE A+D+ NKKERR +SLNRNF+GDYL LD+ P+LR +GKR++V+F+ V KYDRRFK + RDLILT K +Y+IGR+K+ +G KGQ EV+KR ++++ + ++LS D+F +I + EYDS++E FKTEF+ +L KRY E T R L +KF + F VK EG+ G V+ DVA V T+++ +GLP+N++P RD RA I + +G + + + + + + R + PN QSG PS+ + + V P + + D ++ K + + G +P +P V + ALY Y+A DTDELS ++I+++RE D GWWTG++ N+ GL P NYV+K+
Sbjct: 4 KERYHWQSHNVKHSGVDDMVLLPKISEDAIVDNLKKRYMDDFIFTYIGPVLISVNPFKQMPYFTDKEIELYQGAAQYENPPHIYALADNMYRNMLIDQENQCVIISGESGAGKTVAAKYIMSYVSKVSGGGSKVQHVKDIILLSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRVVSQNPQERNFHIYYQLTEAAVGDQKESLGITTPDYYYYLNQSGAYKVDDIDDRKDFQETMKAMRVIGIPAEHQQMVLQIVAGILHLGNLSFREAGNYAAVENDDFLAFPAFLLGIEQARLKEKLTSRQMDSKWGGKSETIEVTLNVEQANYTRDALAKALYARVFDYLVEAINRAIQKDHEEYNVGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIKWTPIDYFNNKIVCDLIENKVNPPGIMSVLDDVCATMHAKGEGADATLLQKLRAQIGSHEHFNSWNQGFIVHHYAGKVSYDVEGFCERNRDVLFTDLIELMQSSEHSFIQALFPENIQSEKKGRPT-TVASKIKKQANDLVNTLMKCTPHYIRCIKPNETKRPRDWEESRVKHQAEYLGLRENIRVRRAGYAYRRIFKKFLQRYAILTRETWPEWHGEERKGVEYLLRTVNMDPDQYQMGRTKVFVKAPESLFLLEEMRERKYDGYARAIQKAWRKHVAHKRYMKMREEASDILLNKKERRRNSLNRNFVGDYLGLDDRPELRQFLGKRDRVDFADSVNKYDRRFKSVKRDLILTSKGLYMIGREKVTKGPDKGQVREVLKRHIELNKIEGVSLSTLQDDFFIIHEA-EYDSLLESMFKTEFLSLLVKRYEERTQRKLHMKFANSLEFKVKKEGWGGWPGGGGPRQVSFVQGQGDVA--VLKPSGKQFTIAIGQGLPNNSRPTRRDAPSGRSRPQNRATARIPVSHAPAGPQFRPPQQQHQQQAPMTQQRQSAGPQRGN----PNHRQSGIGGDAPSLPRQGASTRARVEPSRQEPQDLPFMRVPDKGAAGLQRRLSQERKPPPGAGRPKPAPKPKPRVPQCRALYPYDAQDTDELSFNANEVIDVLREVTDPSGWWTGRLRNKQGLFPGNYVEKL 1119
BLAST of Myosin IE vs. Ensembl Sea Lamprey
Match: myo1f (myosin IF [Source:ZFIN;Acc:ZDB-GENE-081104-506]) HSP 1 Score: 1126.69 bits (2913), Expect = 0.000e+0 Identity = 581/1136 (51.14%), Postives = 777/1136 (68.40%), Query Frame = 3
Query: 63 KNMHHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIIS-GESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRMN-KEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELK-NPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPEG-FQGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTKPGNRDLRAIQAILPTLEKSGIRIKRADTKKVINQTQSFMKSNQQIDRNSTDKLPNLPQ-SGKAKFPSMSQMRMTPVMGVNPRQSQITDEELVKSV-------SKNSKRESN---ITDXXXXXXXXXXX----------------XXXXXVNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 3377
K +HW S K+S DD+VLL K+++D+I ENLKKR MDD I+TYIG VLI+VNPFK++ FT +EI +YQGAA +ENPPHIYA++D M+RNM+ID E+QCVIIS GESGAGKTV+AK+IM Y+SKVSGG +V+ +K+IIL+SNPLLEAFGNAKTVRNNNSSRFGKY EIQF RGGEP GG IS FLLEKSRVV QN ERNFHI+YQL+ G +E GI+TPDYY YLNQ+G Y VDDTDD +F+ TM AM+V+G+ DEQ +L IVA +LHLGN+ F+E A + L FP +LLG+E+ L K+ SR M + K ++I + N +QA RDAL+KAL+SR+FD++V +IN A+ ++ NIG+LDIYGFEIF KNGFEQFCIN+VNEKLQQIFIELTLKAEQ+EYVQEG++WTP+ YFNNK+VCDLIE K NPPGV SILDDVCAT + D + K+ +H+++ + GF + HYAGKVSY+ EGFCERNRD L D++E+MQ S PF LFPEN+ K R T T S+I+KQANDLV L +C PHYIRCIKPNETK+ RDWE RV QV YLGLRENI VRRAG+AYRR F+KF+QRYAIL+ ETWP W GD ++GI H+++ ++ Q+Q+G++K+FIK PESLFLLEE R+RKF+ +A+ IQ +R+ NA K Y ++RE+A+D+ NKKERR +S+NRNF+GDYL +D+ P+LR + +RE+V+F+ V KYDRRFK + RDLILT K +YLIGR+K+K+G +KGQ +EV+K K++I + I+LS D+ ++ +E D+++E FKTE + +L K + E+T + L L F+ + F VK EG F+ G +++++F KT DVA + +TV++ RGLPS+++P +++ + +G K+ T + + QQ R+ P+ Q +G AK P+ +Q + G RQ Q L + + +KR+ + + D+ + + A R A+Y Y+A DTDE+S G++ +L+RED GWW+G I + G+ P NYV+KI
Sbjct: 4 KEHYHWTSGNVKHSGVDDMVLLSKVTEDAIVENLKKRLMDDWIFTYIGPVLISVNPFKQMPYFTDREIDIYQGAAQFENPPHIYALSDFMYRNMLIDSENQCVIISSGESGAGKTVAAKYIMSYVSKVSGGGDKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGNISNFLLEKSRVVSQNTEERNFHIYYQLLTGSSGTQKENLGISTPDYYFYLNQTGTYVVDDTDDNKDFQETMAAMQVIGILPDEQAMVLQIVAGILHLGNISFMEQGNYAAVESLDYLAFPAHLLGIEQDRLMEKLTSRTMDSKWGGKSESITVTLNTEQAAYTRDALAKALHSRLFDFLVQEINKAIRKEREEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIKWTPIEYFNNKIVCDLIENKVNPPGVMSILDDVCATMHAKGEGADTTLLQKLQAGIGCHEHFNTWNRGFVVHHYAGKVSYDVEGFCERNRDVLFPDLVELMQSSQYPFFYSLFPENLQVEKKGRPT-TASSKIKKQANDLVNTLMRCTPHYIRCIKPNETKRPRDWEESRVRHQVEYLGLRENIRVRRAGFAYRRVFQKFLQRYAILTAETWPAWRGDERQGITHILRAVNMEADQFQMGRSKVFIKAPESLFLLEEMRDRKFDAFARTIQKAWRKFNAYKQYARMREQASDILLNKKERRRNSINRNFVGDYLGMDDRPELRQFLARRERVDFADVVTKYDRRFKLVKRDLILTAKCLYLIGREKVKKGPEKGQLMEVLKNKIEIDKIQSISLSTLQDDMFIVH-EREDDNLLESVFKTELLSLLCKHFEELTKQKLALNFNNTLEFRVKKEGWFEKGGTRQVSFVC----KTGDVA--ILKSSGRVLTVTIGRGLPSSSRPNRKEI---------MRGTGREQKKNSTCGITPVQAGYKGHQQQQQRHRNGAPPSQRQPTGPAKAPAYAQPN---IRGGTKRQQQQDRPSLPRHATNVHAPTAAQTKRDRDFMRVPDQGAAGMQRQASQVRPTPGGGRSKLPMQARAAAFPRCRAIYQYDAQDTDEISFSIGEVFDLIREDPSGWWSGCIRGKEGMFPGNYVEKI 1119
BLAST of Myosin IE vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000990.1 (pep scaffold:Pmarinus_7.0:GL476918:15609:106669:1 gene:ENSPMAG00000000865.1 transcript:ENSPMAT00000000990.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 548.125 bits (1411), Expect = 2.015e-176 Identity = 294/718 (40.95%), Postives = 442/718 (61.56%), Query Frame = 3
Query: 114 DLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGI-TTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIE-----GQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRMNKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKIN--VAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTG-------------FTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRE 2204
D+VLL +++DS +NL++RF D YTYIGNV+++VNP+K L+I++ +++ Y+ YE PH++AIAD +R++ + QC++I+GESGAGKT +K++M Y++ V G V +KE +L+SNP+LEAFGNAKT+RN+NSSRFGKY++I+F+ G+P+GG I +LLEKSRVV Q Q ERNFHIFYQL+ G + + P Y+YL Q V+ +D F AM+V+G +E ++ +A VL LGN++F++ G + FK+ + L C LLGL++ L + R + NKE+ + N Q ARDAL K LY+R+F ++V +IN + + I +G+LDIYGFEIF N FEQF IN+ NEKLQQIFIELTLK EQ+EY++EGV+W + YFNN ++CDLIE + +LDD C VTDS F+ K++ +H+ H++ F + HYA KV+Y +GF ++N D L D+ + M +S + DLFPE ++ + LT S+++ N L+ L P+YIRC+KPN+ K + ++++ V++QV YLGL EN+ VRRAGY +R+ + + RY +L +TWP W GD K+G++ ++ + ++ G TK+FIK P +LF LE +R + + A +IQ +R H+L +++
Sbjct: 18 DMVLLDPLTEDSFLKNLRERFKHDEFYTYIGNVVLSVNPYKPLTIYSAEKVEEYRNRNIYELSPHVFAIADEAYRSLRDADKDQCILITGESGAGKTEVSKYVMSYVAAVCGKGEEVNMVKEQLLQSNPVLEAFGNAKTIRNDNSSRFGKYMDIEFNFKGDPVGGIIRNYLLEKSRVVYQLQGERNFHIFYQLLAGASPSLLASLKLQQNPSVYTYLMQGKTAHVEGLNDSQSFHTVQKAMQVIGFSDEEIATVWEALAVVLKLGNIVFVDIPRTNGLDECTFKESKELDEVCALLGLDDELLERALTKRTV--EANKEK-VSTTLNMAQGKYARDALCKNLYNRLFSWLVSRINESIKVKSKIKKKVMGVLDIYGFEIFEVNSFEQFIINFCNEKLQQIFIELTLKEEQEEYIREGVKWIQIEYFNNAIICDLIENNVFVYLGPMLDDECMRPGNVTDST---FLDKLNDKCGKHEHFEKHNSASSARSTTKRHYRCFRVQHYAVKVTYSVDGFVDKNNDLLFRDISQTMWQSQRKLVRDLFPEGNPSKQSLKRPLTASSQLKTSVNALMKDLLIKNPNYIRCLKPNDRKSSSLFQDELVLNQVRYLGLMENVRVRRAGYVFRQLYALCLHRYKMLGSQTWPHWNGDAKEGVKSILVDLKLPQEEYAFGVTKVFIKSPTTLFQLERKRTERMHELATLIQKTYRGYKCRTHFLLMKK 729
BLAST of Myosin IE vs. Ensembl Sea Lamprey
Match: myo10l1 (myosin X, like 1 [Source:ZFIN;Acc:ZDB-GENE-080425-1]) HSP 1 Score: 459.914 bits (1182), Expect = 1.137e-137 Identity = 260/678 (38.35%), Postives = 393/678 (57.96%), Query Frame = 3
Query: 111 DDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKL-SIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQ-------IKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRMNKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTG---FTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFP-------ENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAIL--SKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKD 2084
+D+ L + + +I NL RF D+ IYTYIG++L AVNP++ + ++ + +G Y E PPHIYAIA+ +R + +SQCV+ISGESGAGKT S K I+ ++S+ S GAG+ Q ++ ILES+P++EAFGNAKTV NNNSSRFGK++++ F + G GG+I +LLEK+RVV QN ERNFH+FY L+ G + +E ++ P+ Y YL QSG D DD F+ M AM+VM K+E +L +++ VL LGN+ F+ A+ +K + LLGL+ +L+ + R M + + + I +QA +R++++ ALYS+ F +I+ KIN + N + +IGILDI+GFE F N FEQF INY NEKLQ+ F + EQ EY +EG+ W +N+ +N DLIE K G+ +++++ + D + K+ G + Y+ F I HYAG+V Y+ GF E+NRD D++ ++++S FI DLF E K+ TV S+ + + L+ L+ P ++RCIKPN K A+ +E+ V++Q+ Y G+ E + +RRAGY RRPF+ F RY +L ++E D K L++ D + WQ+G+TK+F++D
Sbjct: 61 EDMSALADLHEGAIMHNLHLRFHDNKIYTYIGSILAAVNPYRLIDGLYDKAAVGRYAQNLLGELPPHIYAIANECYRCLWKRLDSQCVLISGESGAGKTESTKLILNFLSETSQGAGKAAQSGPTNTNVETAILESSPIMEAFGNAKTVYNNNSSRFGKFIQLHFSQQGFIQGGRILDYLLEKNRVVRQNPGERNFHVFYALLAGTTAEQKESLCLSEPNSYKYLAQSGCISDDACDDVKSFEKVMTAMQVMAFVKEEVREVLKLLSGVLQLGNIEFVTA-GGAQISNKDVVSVVSELLGLDSLQLSEVLTQRSM---ILRGEEISTPLTIEQAEDSRNSMAMALYSQCFSWIIQKINGRIKGNDNFKSIGILDIFGFENFEVNRFEQFNINYANEKLQEYFNKHIFSLEQLEYNREGIIWEDINWMDNGECLDLIEKK--LGMLALINEES----RFPKGTDFTMLEKLHGQHATNQFYTKPRVADHQFGIKHYAGEVLYDVRGFLEKNRDTFRDDLLNVLRESGIDFIYDLFERVSGGGGEETLKAGAKQRRPTVSSQFKDSLHSLMASLSTSNPFFVRCIKPNMKKLAQRFEHVVVLNQLRYSGMLETVRIRRAGYPVRRPFQDFYSRYKVLLGNREV----PDDPKGKCIALLRVYDAKNAAWQLGRTKVFLRD 724
BLAST of Myosin IE vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000498.1 (pep scaffold:Pmarinus_7.0:GL479744:368:24152:-1 gene:ENSPMAG00000000443.1 transcript:ENSPMAT00000000498.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 422.935 bits (1086), Expect = 2.000e-134 Identity = 243/655 (37.10%), Postives = 367/655 (56.03%), Query Frame = 3
Query: 111 DDLVLLPKISQDSITENLKKRFMD-DCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEF----KDKRSLQFPCYLLGLEESELATKMASREMADRMNKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMN-IGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHY----SSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLF--------PENVTDLKNKRSTLTVGSRIRKQAND-----------------LVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKE 1970
+DL L + + ++ NLK RF + + IYTY G VL+A+NP+++L I+ + I Y G + PHI+A+A+ ++ M D ++Q +I+SGESGAGKTVSAK+ M Y + V G A I+E +L SNP++EA GNAKT RN+NSSRFGKY+EI F+R +G + +LLEKSRVV Q + ERN+H+FYQL E + + + + Y Q G ++D DD + + T A ++G+ Q+ I I+A +LHLGNV ++ E K+ + L C LLGLE ++A + R+++ + V R QA ARDAL+K +Y+++F +IV +IN A+ + + IG+LDIYGFE F N FEQFCINY NEKLQQ F K EQ+EY++E + WT +++++N+ DLIE K GV +LD+ C K+ D + K+ +L + + + F I H+A KV Y+C+GF E+NRD + + I +++ S + + F P + +R++ T G+R R A L+ L PHY+RCIKPN+ K A ++ R V Q+ G+ E I + AGY R +++F RY +L ++
Sbjct: 5 NDLTALSYLHEPAVLHNLKVRFAESNHIYTYCGIVLVAINPYEQLPIYGEDIIFAYSGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASEA-NIEEKVLASNPIMEAIGNAKTTRNDNSSRFGKYIEIGFNRQYLIVGANMRTYLLEKSRVVFQAEEERNYHVFYQLCASAELPEFKDLHLEPAEAFVYTAQGGNAVIEDVDDGEDLERTRRAFTLLGIGASYQMGIFKIIAGILHLGNVEVQSQDREQETCFVNKEDKHLNIFCELLGLERDQMAHWLCHRKIS---TGAETYVKPMGRAQAQNARDALAKHVYAQLFSWIVHRINKALRSSTKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNLHVFKLEQEEYMREEIPWTLIDFYDNQPCIDLIEAK--LGVLDLLDEEC----KMPKGSDQSWAQKLYEKHLGRGKHFLKPRMSNVAFIICHFADKVEYQCDGFLEKNRDTVYEEQINILKASQSSLLTLAFVSRPPCLHPTGTPPPRRRRNS-TEGNRHRSSARTKARSHVATFQFRNSLHLLMETLNATTPHYVRCIKPNDDKMAFTFDPKRAVQQLRACGVLETIRLSAAGYPSRWTYQEFFNRYRVLMRK 648
BLAST of Myosin IE vs. Ensembl Yeast
Match: MYO5 (One of two type I myosin motors; contains proline-rich tail homology 2 (TH2) and SH3 domains; MYO5 deletion has little effect on growth, but myo3 myo5 double deletion causes severe defects in growth and actin cytoskeleton organization; MYO5 has a paralog, MYO3, that arose from the whole genome duplication [Source:SGD;Acc:S000004715]) HSP 1 Score: 691.804 bits (1784), Expect = 0.000e+0 Identity = 433/1151 (37.62%), Postives = 650/1151 (56.47%), Query Frame = 3
Query: 78 WQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGG-AGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQ-QAEFKDKRSLQFPCYLLGLEESELATKMASREMADRMNKEQNIV--ILFNRQQAFQARDALSKALYSRMFDYIVDKINVAM-AINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPK----WTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQV------NATK------------HYLKLRERAADLFYNKKERREHSL--NRNFIGDYLFLDENPQLRILIGK----REKVEFS----SFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISV--SKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPEGFQGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTKPGNRDLRAIQAILPTLEKSGIRIKRADTKKVINQTQSFMKSNQQIDRNSTDKLPNLPQSGKAKFPSMSQMRMTPVMGVNPRQSQITDEELVKSVSK-----------NSKRESNITDXXXXXXXXXXXXXXXXVNRVEALYAYEATDT-DELSIYPGDIIELVREDNEGWWTGKI--GNRTGLIPSNYVK 3371
+ S K DL LL KIS ++I ENLKKRF++ IYTYIG+VLI+VNPF+ L I+T + Y+G E PPH++AIA++M+ NM E+QCVIISGESGAGKT +AK IM+YI+ S + +IK+++L +NPLLE+FG AKT+RNNNSSR GKY+EI+F+ EP G I+ +LLEK RVV Q +NERNFHIFYQ +G R+ FG+ P+ Y Y +G + DD +++ T+ AM V+GL ++EQ I ++AA+L +GNV FIE ++ A+ +D F YLL ++ L + R M ++ V + N QA RDAL+KA+Y+ +FD+IV ++N ++ A + +IGILDIYGFEIF N FEQ CINYVNEKLQQIFI+LTLK+EQ+ Y +E +QWTP+ YF+NKVVCDLIE + PPG+F+ ++D ATA +++ D F +++ N H+ S F I HYAG V+Y+ +G ++N+DQL D++E++ +TN F+ +FP+ V D ++KR T G +I K ANDLV L+K QP YIR IKPNETK D+++ +V+ Q+ YLGL+EN+ +RRAG+AYR+ FEKF++R+ +LS W GD ++++++ + I ++Q+G T +FIK PE+LF LE R+R +++ A IQ +R+ ATK Y KLR+ + +KERR SL R F+GDYL +E+ I + +EKV FS + K+ R ++L + +LT +Y++G+ ++ Q K+D+ + ++L+ D++V I + S + D +I FKTE I L KR N+ +Q+K + I + KP +V Q + ++ G + + T+SV RG P N++ ++ R +I S + T++ ++ + R+S K P P G + + P + QS + S R++NI PP P + EA Y + + + EL + GD+I + RE+ GW GK+ G++ G +P+ Y+K
Sbjct: 28 FDSSKKKEVGVSDLTLLSKISDEAINENLKKRFLNATIYTYIGHVLISVNPFRDLGIYTDAVMNEYKGKNRLEVPPHVFAIAESMYYNMKSYNENQCVIISGESGAGKTEAAKRIMQYIAAASSTHTESIGKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIKFNNQFEPCAGNITNYLLEKQRVVSQIKNERNFHIFYQFTKGASDAYRQTFGVQKPEQYVYTAAAGCISAETIDDLQDYQETLKAMRVIGLGQEEQDQIFRMLAAILWIGNVSFIENEEGNAQVRDTSVTDFVAYLLQIDSQLLIKSLVERIMETNHGMKRGSVYHVPLNIVQADAVRDALAKAIYNNLFDWIVSRVNKSLQAFPGAEKSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKSEQETYEREKIQWTPIKYFDNKVVCDLIEARRPPGIFAAMNDSVATAHADSNAADQAFAQRLNLFTTNP-HFDLRSNKFVIKHYAGDVTYDIDGITDKNKDQLQKDLVELIGTTTNTFLATIFPDTV-DRESKRRPPTAGDKIIKSANDLVETLSKAQPSYIRTIKPNETKSPNDYDDRQVLHQIKYLGLQENVRIRRAGFAYRQVFEKFVERFYLLSPHCSYAGDYTWQGDTLDAVKYILQDSSIPQQEYQLGVTSVFIKTPETLFALEHMRDRYWHNMAARIQRAWRRFLQRRIDAATKIQRTIRERKEGNKYEKLRDYGTKVLGGRKERRSMSLLGYRAFMGDYLSCNESKSKGAYIKRQVSIKEKVIFSIHGEALHTKFGRSAQRLKKTFLLTPTTLYIVGQTLVQNAMTYTQ-----DYKIDVRNIQAVSLTNLQDDWVAIKLASSGQPDPLINTYFKTELITHL-KRLND----KIQIKIGSAIEYQKKPGKLH---------SVKCQ---INESAPKYGDIYKSSTISVRRGNPPNSQV-HKKPRKKSSISSGYHASSSQA----TRRPVSIAAAQHVPTAPASRHS--KKPAPPPPGMQNKAATRRSVPNPASTLTASQSNARPSPPTAATRATPAATPAAAAMGSGRQANIPPPPPPPPPSSKPKEPM----FEAAYDFPGSGSPSELPLKKGDVIYITREEPSGWSLGKLLDGSKEGWVPTAYMK 1143
BLAST of Myosin IE vs. Ensembl Yeast
Match: MYO3 (One of two type I myosins; localizes to actin cortical patches; deletion of MYO3 has little effect on growth, but myo3 myo5 double deletion causes severe defects in growth and actin cytoskeleton organization; MYO3 has a paralog, MYO5, that arose from the whole genome duplication [Source:SGD;Acc:S000001612]) HSP 1 Score: 687.182 bits (1772), Expect = 0.000e+0 Identity = 396/949 (41.73%), Postives = 579/949 (61.01%), Query Frame = 3
Query: 114 DLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGG-AGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQ-QAEFKDKRSLQFPCYLLGLEESELATKMASREMADRMNKEQNIV--ILFNRQQAFQARDALSKALYSRMFDYIVDKINVAM-AINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPK----WTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXK-FNHYAKV-----------------IQIFFRQVNATKHYLKLRERAADLFYNKKERREHSL--NRNFIGDYLFLDENPQ----LRILIGKREKVEFS----SFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNF--VVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPEGFQGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTK 2843
DL LL KIS +SI ENLKKRF + IYTYIG+VLI+VNPF+ L I+T + Y+G E PPH++AIA++M+ N+ E+QCVIISGESGAGKT +AK IM+YI+ S + + +IK+++L +NPLLE+FG AKT+RNNNSSR GKY+EI+F+ EP G I+ +LLEK RVV Q +NERNFHIFYQ +G ++MFG+ P+ Y Y +G D DD +++ T+ AM +GL ++EQ I ++AA+L +GN+ FIE ++ A+ D F YLL ++ S L + R M ++ V + N QA RDAL+KA+Y+ +FD+IVD++NV++ A D +IGILDIYGFEIF N FEQ CINYVNEKLQQIFI+LTLKAEQ+ Y +E ++WTP+ YF+NKVVCDLIE KNPPG+ + ++D ATA +++ D F +++ N N ++ + F I HYAG V+Y+ G ++N+DQL D+IE++ +TN F+ +FP++V D +KR T G +I K AN+LV L+K +P YIR IKPN+TK D+++ +V+ QV YLGL+EN+ +RRAG+AYR+ FEKF++R+ +LS + W GD + ++ +++ A I + ++Q+G T +FIK PESLF LE+ R++ +N A++ IQ R+ Y+KLR+ L KKERR SL R F+GDYL +E+ +R +G ++KV FS K+ R ++L + ILT K Y+IG+ + + K Q K+D+ + ++L+ D++ V++ S + D +I FKTE + L K N + +K I + +P ++K D A K G + + T+ V RG P+N+K
Sbjct: 40 DLTLLSKISDESINENLKKRFKNGIIYTYIGHVLISVNPFRDLGIYTNAVLESYKGKNRLEVPPHVFAIAESMYYNLKSYNENQCVIISGESGAGKTEAAKRIMQYIAAASNSHSESIGKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIKFNSQFEPCAGNITNYLLEKQRVVGQIKNERNFHIFYQFTKGASDTYKQMFGVQMPEQYIYTAAAGCTTADTIDDVKDYEGTLEAMRTIGLVQEEQDQIFRMLAAILWIGNISFIENEEGNAQVGDTSVTDFVAYLLQVDASLLVKCLVERIMQTSHGMKRGSVYHVPLNPVQATAVRDALAKAIYNNLFDWIVDRVNVSLQAFPGADKSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKAEQETYEREKIKWTPIKYFDNKVVCDLIEAKNPPGILAAMNDSIATAHADSNAADQAFAQRLNLFNSNP-YFELRANKFVIKHYAGDVTYDINGITDKNKDQLQKDLIELIGTTTNTFLSTIFPDDV-DKDSKRRPPTAGDKIIKSANELVETLSKAEPSYIRTIKPNQTKSPNDYDDHQVLHQVKYLGLQENVRIRRAGFAYRQTFEKFVERFYLLSPDCSYAGDYTWDGDTLEAVKLILRDAMIPEKEFQLGVTSVFIKTPESLFALEDMRDKYWYNMAARIQRAWRRFLQRRIDAAIKIQRTIREKKGGNKYVKLRDYGTKLLAGKKERRSMSLLGYRAFMGDYLSCNESKTKGSYIRRQVGIKDKVVFSIKGECLHSKFGRSAQRLKKVFILTKKTFYIIGQTREQNAMKYTQ-----DYKIDVGKIKQVSLTNLQDDWMGVILVNSTQSDPLINTPFKTELMTRLKK-----LNEKIMIKVGPTIEYHKQPNKLH-----------TVRSKISDSAPKY-GDIYKSSTIYVRRGHPANSK 964
BLAST of Myosin IE vs. Ensembl Yeast
Match: MYO4 (Type V myosin motor involved in actin-based transport of cargos; required for mRNA transport, including ASH1 mRNA, and facilitating the growth and movement of ER tubules into the growing bud along with She3p; MYO4 has a paralog, MYO2, that arose from the whole genome duplication [Source:SGD;Acc:S000000027]) HSP 1 Score: 449.514 bits (1155), Expect = 9.862e-137 Identity = 265/701 (37.80%), Postives = 407/701 (58.06%), Query Frame = 3
Query: 105 TADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLS-IFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGR-----VEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEF-KDKRSLQFPCYLLGLEESELATKMASREMADRMNKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAM-AINIDDMN-----IGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSH--STGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPF---IVD---LFPENVTDLKNKRSTL-----------TVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDV------KKGIQHLMKT---ADIND-GQWQIGKTKLFIK 2081
+ DDL L +++ ++ +KKR+M+ IYTY G VLIA NPF K+ +++++ I Y E PH++AIA+ +R M+ + +Q V++SGESGAGKTVSAK+IM Y + V R + QI+ IL +NP++EAFGNAKT RN+NSSRFGKY++I FD G KI +LLEKSR+V Q + ERN+HIFYQ++EG + +++ +++P Y Y NQ G + D+ E+K T A+ ++G+ + QL I I+A +LH+GN+ + A ++++LQ C LLG++ A + +++ R K IV N QA ARD+++K +YS +FD++VD IN + +D + IGILDIYGFE F KN FEQFCINY NEKLQQ F + K EQ+EYV+E ++W+ + + +N+ DLIE N G+ S+LD+ +S +K + + N+ T F + HYA V YE EGF E+NRD +S+ +++ + +TNP I+D L ++ + +N + T+GS +K +L+ + HYIRCIKPN KK +++N V+ Q+ G+ E I + AG+ R F++F+QRY +L+ + W+G + K+ I + ++ A I+D ++QIG TK+F K
Sbjct: 72 STDDLTTLSYLNEPAVLHAIKKRYMNGQIYTYSGIVLIAANPFDKVDHLYSREMIQNYSSKRKDELEPHLFAIAEEAYRFMVHEKANQTVVVSGESGAGKTVSAKYIMRYFASVQESNNREGEVEMSQIESQILATNPIMEAFGNAKTTRNDNSSRFGKYLQILFDENTTIRGSKIRTYLLEKSRLVYQPETERNYHIFYQILEGLPEPVKQELHLSSPKDYHYTNQGGQPNIAGIDEAREYKITTDALSLVGINHETQLGIFKILAGLLHIGNIEMKMTRNDASLSSEEQNLQIACELLGIDPFNFAKWIVKKQIVTRSEK---IVTNLNYNQALIARDSVAKFIYSTLFDWLVDNINKTLYDPELDQQDHVFSFIGILDIYGFEHFEKNSFEQFCINYANEKLQQEFNQHVFKLEQEEYVKEEIEWSFIEFSDNQPCIDLIE--NKLGILSLLDEESRLPSGSDESWASKLYSAFNKPPSNEVFSKPRFGQTKFIVSHYAVDVEYEVEGFIEKNRDSVSLGHLDVFKATTNPIFKQILDNRELRSDDAPEEQNTEKKIMIPARLSQKKPTLGSMFKKSLGELMAIINSTNVHYIRCIKPNSEKKPWEFDNLMVLSQLRACGVLETIRISCAGFPSRWTFDEFVQRYFLLTD--YSLWSGILYNPDLPKEAIVNFCQSILDATISDSAKYQIGNTKIFFK 765
BLAST of Myosin IE vs. Ensembl Yeast
Match: MYO2 (Type V myosin motor involved in actin-based transport of cargos; required for the polarized delivery of secretory vesicles, the vacuole, late Golgi elements, peroxisomes, and the mitotic spindle; MYO2 has a paralog, MYO4, that arose from the whole genome duplication [Source:SGD;Acc:S000005853]) HSP 1 Score: 437.573 bits (1124), Expect = 7.127e-132 Identity = 267/707 (37.77%), Postives = 402/707 (56.86%), Query Frame = 3
Query: 105 TADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKL-SIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSG-GAGRVEQIKEI------ILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFK-DKRSLQFPCYLLGLEESELATKMASREMADRMNKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAM---AINIDDMN--IGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSH--STGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFP---------ENVTDLK---------------NKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAIL-SKETW-----PKWTG--DVKKGIQHLMKTADINDGQWQIGKTKLFIK 2081
+DL L +++ ++ +K+R+ IYTY G VLIA NPF ++ ++TQ I Y G E PH++AIA+ +R M D ++Q +++SGESGAGKTVSAK+IM Y + V + V+ E+ IL +NP++EAFGNAKT RN+NSSRFGKY+EI FD+ IG +I +LLE+SR+V Q ERN+HIFYQL+ G +E +T Y Y+NQ G K++ DD E+K T+ A+ ++G+ K+ Q I I+AA+LH+GN+ + + A D+ +L+ C LLG++ A + +++ R K IV N QA A+D+++K +YS +FD++V+ IN + A+N D ++ IG+LDIYGFE F KN FEQFCINY NEKLQQ F + K EQ+EYV+E ++W+ + + +N+ DLIE N G+ S+LD+ +S K +D S NK T F + HYA V+Y+ EGF E+NRD +S +E+++ STN ++++ E L+ N++ TL GS ++ +L+ + HYIRCIKPN K+A ++N V+ Q+ G+ E I + AG+ R FE+F+ RY IL E W K T D+ ++ ++ + ++QIG TK+F K
Sbjct: 71 ATEDLTSLSYLNEPAVLHAIKQRYSQLNIYTYSGIVLIATNPFDRVDQLYTQDMIQAYAGKRRGELEPHLFAIAEEAYRLMKNDKQNQTIVVSGESGAGKTVSAKYIMRYFASVEEENSATVQHQVEMSETEQKILATNPIMEAFGNAKTTRNDNSSRFGKYLEILFDKDTSIIGARIRTYLLERSRLVYQPPIERNYHIFYQLMAGLPAQTKEELHLTDASDYFYMNQGGDTKINGIDDAKEYKITVDALTLVGITKETQHQIFKILAALLHIGNIEIKKTRNDASLSADEPNLKLACELLGIDAYNFAKWVTKKQIITRSEK---IVSNLNYSQALVAKDSVAKFIYSALFDWLVENINTVLCNPAVN-DQISSFIGVLDIYGFEHFEKNSFEQFCINYANEKLQQEFNQHVFKLEQEEYVKEEIEWSFIEFNDNQPCIDLIE--NKLGILSLLDEESRLPAGSDESWTQKLYQTLDKSPTNKVFSKPRFGQTKFIVSHYALDVAYDVEGFIEKNRDTVSDGHLEVLKASTNETLINILEGLEKAAKKLEEAKKLELEQAGSKKPGPIRTVNRKPTL--GSMFKQSLIELMNTINSTNVHYIRCIKPNADKEAWQFDNLMVLSQLRACGVLETIRISCAGFPSRWTFEEFVLRYYILIPHEQWDLIFKKKETTEEDIISVVKMILDATVKDKSKYQIGNTKIFFK 769
BLAST of Myosin IE vs. Ensembl Yeast
Match: MYO1 (Type II myosin heavy chain; required for wild-type cytokinesis and cell separation; localizes to the actomyosin ring; binds to myosin light chains Mlc1p and Mlc2p through its IQ1 and IQ2 motifs respectively [Source:SGD;Acc:S000001065]) HSP 1 Score: 404.445 bits (1038), Expect = 5.100e-119 Identity = 258/713 (36.19%), Postives = 396/713 (55.54%), Query Frame = 3
Query: 111 DDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATY-------EN-----PPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGR----------VEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCE----KDIREMFGITTPDY--YSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQ-QQAEFKDKRSLQFPCYLLGLEESELATK-MASREMADRMNKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMN-IGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNN-KVVCDLIELKNPP-GVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLF-PE-----------NVTDLKNKRSTL-----TVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKET------WPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIK 2081
+++ L +++ S+ NL+KR+ D IYTY G L+A+NP+ L+++++ I +Y EN PPHI+AIA+ + N++ + + Q ++++GESGAGKT + K I++Y++ ++ G+ VE + IL+SNP+LE+FGNA+TVRNNNSSRFGK+++I+F+ G G I +LLEKSR+V QN ERN+HIFYQL+ G + K++R + DY S NQ + ++D ++ FK + A+ ++G KD+ I +VA +L +GN+ F+ + +QA FK+ + C LG++E + T + R A + Q+ N QQA +ALS+ LY R+F YIVD IN + +N IG+LDI GFEIF N FEQ CINY NEKLQQ F EQ EY++E +QW ++Y + ++ DLIE K PP GV +LD+ +S +K ++ D N +K S GF + HYAG V Y EG+ +N+D L+ +++ ++ S N I LF PE N+++ + K+S T SR R+Q L+ +L PH++RCI PN KK + + ++DQ+ G+ E I + R GY R F++F QRY IL E K K+ + L+ + ++ ++IG TKLF K
Sbjct: 78 ENMSELTHLNEPSVLYNLEKRYDCDLIYTYSGLFLVAINPYHNLNLYSEDHINLYHNKHNRLSKSRLDENSHEKLPPHIFAIAEEAYENLLSEGKDQSILVTGESGAGKTENTKKILQYLASITSGSPSNIAPVSGSSIVESFEMKILQSNPILESFGNAQTVRNNNSSRFGKFIKIEFNEHGMINGAHIEWYLLEKSRIVHQNSKERNYHIFYQLLSGLDDSELKNLR-LKSRNVKDYKILSNSNQDIIPGINDVEN---FKELLSALNIIGFSKDQIRWIFQVVAIILLIGNIEFVSDRAEQASFKN--DVSAICSNLGVDEKDFQTAILRPRSKAGKEWVSQS----KNSQQAKFILNALSRNLYERLFGYIVDMINKNLDHGSATLNYIGLLDIAGFEIFENNSFEQLCINYTNEKLQQFFNNHMFVLEQSEYLKENIQWDYIDYGKDLQLTIDLIESKGPPTGVLPLLDEEAVLPKSTDESFYSKLISTWD-QNSSKFKRSRLKNGFILKHYAGDVEYTVEGWLSKNKDPLNDNLLSLLSSSQNDIISKLFQPEGEKSSSAGVEANISNQEVKKSARTSTFKTTSSRHREQQITLLNQLASTHPHFVRCIIPNNVKKVKTFNRRLILDQLRCNGVLEGIRLAREGYPNRIAFQEFFQRYRILYPENSTTTTFSSKLKASTKQNCEFLLTSLQLDTKVYKIGNTKLFFK 779
BLAST of Myosin IE vs. Ensembl Nematostella
Match: EDO35007 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SMP8]) HSP 1 Score: 676.781 bits (1745), Expect = 0.000e+0 Identity = 345/716 (48.18%), Postives = 480/716 (67.04%), Query Frame = 3
Query: 102 STADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYEN--PPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSG-GAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKD-IREM-FGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRMNKEQNIVI-LFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMD---GSNLN-KDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLK-----NKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRE 2204
+T D++ +P +S+ SI NLK R + IYT IG VLI+VNPFKK++I+ + +Y G E PPH+Y +A+NMF NM+I+ +SQCVIISGESGAGKTVSAK +M ++SKV G G+ VE++K+II++SNPLLEAFGNAKTV NNNSSRFGK++EIQ+ R G+P GGKIS FLLEKSRVV Q Q ERN+HIFYQL+ GC D + E+ + + Y YLNQ+GVY ++ TDD S++ T++AMEV+G+ + ++L +VA VLHLGN+ F E QA D L P LL +++ L K+ S M R + + N+ QA ARDAL+KA++ ++F+Y+V+ +N MA D IG+LDIYGFE F NGFEQF INYVNEKLQ +FI+ TLK EQ+EY +EG+ W+ ++YFNN VV LIE + PPG+ +LDDVC+T V++ N + K+ GSN + ++ + + F I HYAGKVSYE EGFCE+N+D LS D++ +MQ ST PF+ D+FP+++ K + T S+IR QA+ LV K+ C PHY+RC+KP E+K DW++ +V+ QV YLGL ENI VRRAG+A+RR F + ++RY++L T K D + ++ +++ ++Q+GKTKLF+K+P+ + LEE R YA IQ +R A K Y +L++
Sbjct: 3 ATVSDMIEIPDVSEASIANNLKIRLKQEEIYTNIGRVLISVNPFKKINIYGMDAVELYSGKKHNEGAKPPHLYEVANNMFENMLIEGDSQCVIISGESGAGKTVSAKHVMGFLSKVCGEGSTEVERVKDIIMQSNPLLEAFGNAKTVMNNNSSRFGKFMEIQYSRSGQPNGGKISTFLLEKSRVVSQGQGERNYHIFYQLLSGCTPDEMSELEIDLGPAESYKYLNQTGVYTIEGTDDVSDYAATINAMEVIGIASSTRNTVLKLVATVLHLGNIQFTEEDNQAVPVDVSMLDAPSRLLSVDKDILLDKLTSYSMETRWGGKVEVTKKTLNKDQAVIARDALAKAIFFQLFEYLVEAVNSTMATRDQDFYIGVLDIYGFESFKVNGFEQFSINYVNEKLQNLFIDFTLKMEQEEYAEEGISWSDIDYFNNDVVLQLIESRRPPGIMGVLDDVCSTLHAVSEGSANTLMDKLRGVIGSNSSFAKYFQAQARHFAITHYAGKVSYESEGFCEKNKDTLSNDLVCLMQSSTEPFVRDMFPDSLYGASAGVGGRKAKSNTGSSKIRTQAHALVSKIRMCTPHYVRCVKPTESKIPLDWDDKKVLHQVRYLGLAENIKVRRAGFAFRREFPRIVERYSLLDPITVRKHQSDPVAACKAILLAGNLDMTKYQVGKTKLFLKEPQMINQLEEARNAIITKYALTIQTVYRGYRARKIYKRLKK 718
BLAST of Myosin IE vs. Ensembl Nematostella
Match: EDO49515 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGF6]) HSP 1 Score: 582.408 bits (1500), Expect = 0.000e+0 Identity = 312/740 (42.16%), Postives = 463/740 (62.57%), Query Frame = 3
Query: 114 DLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTP-DYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIE-----GQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRMNKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMN--IGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTG------------FTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADL--FYNK-KERREHSLNRN 2264
D+VLL +++D+I ENL R+ IYTYIGNV++++NP++K ++T++ I Y+ YE PPHIYAIAD+ +R+M + QC+II+GESG+GKT ++K IM+Y++ V G V+++KE +L+SNP+LEAFGNAKT+RN+NSSRFGKY++I+FD G+P+GG I+++LLEKSR+V QN+ ERNFHIFY L+ G ++ + +T D Y YLNQS V DDK +F AMEV+G +DE ++ +++A+L+LGN E G + +++ L+ C +L + L + R + K + + N QA ARDAL+KA+Y R+F +IVD++N ++ + IG+LDIYGFEIFV N FEQF INY NEKLQQIFIELTLK+EQ+EYV+EG++WT + YFNN V+C+LIE KN G+ ++LD+ C +V+D F+ K+D ++ +HY S F + HYAGKV+Y+ +GF ++N D L + + M +P LFPE +KR T ++ ++ +L+ L P+YIRCIKPNE K A ++ + QV YLGL ENI VRRAG+A+R+ + +QRY +L TWP W G + GI L+K ++ ++ G+TK+FI++P +LF LEE+R+ A +IQ FR K Y +R + +Y + +++R++ RN
Sbjct: 25 DMVLLEPLTEDAIMENLWDRYNAKAIYTYIGNVVVSINPYRKFPLYTREVIAEYRSRNIYELPPHIYAIADDAYRSMRDHNKDQCIIITGESGSGKTEASKVIMQYVAAVCGKGREVDRVKEQLLQSNPILEAFGNAKTLRNDNSSRFGKYMDIEFDFKGDPVGGVITKYLLEKSRLVYQNKGERNFHIFYHLLRGASDNLLDDLRLTRDFDGYHYLNQSECVSVPTKDDKEDFSVVEKAMEVVGFTEDEISAVYKLLSAILNLGNTELEEFTTSDGTEAVTVLNEQVLKNTCEMLQCDVELLLNSLRERTVE---TKTERVHTPLNVAQASYARDALAKAVYQRLFAWIVDRVNDSIQVRKRGKRKVIGVLDIYGFEIFVDNSFEQFIINYCNEKLQQIFIELTLKSEQEEYVREGIEWTTIEYFNNAVICELIE-KNHSGILALLDEECLRPGEVSDLT---FLEKLDKQWIHHEHYESRKDKKYLSDKTLPHGYFRLKHYAGKVTYDVDGFLDKNNDLLFRGLSQCMYSCNHPLTKKLFPEGCPTKSSKRRPKTTATQFKESVAELMKNLKSKNPNYIRCIKPNERKAAGVFDERLIKHQVRYLGLMENIRVRRAGFAFRQEYPVALQRYKMLCPRTWPNWLGAPRDGIVELLKHLNVKPTEYAYGRTKIFIRNPRTLFALEEKRKDGMEDLAVIIQKIFRGWRRKKQYQNMRRSEITIAKYYRRFRDQRDYRRMRN 757
BLAST of Myosin IE vs. Ensembl Nematostella
Match: EDO45835 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRW9]) HSP 1 Score: 509.605 bits (1311), Expect = 5.087e-163 Identity = 287/696 (41.24%), Postives = 413/696 (59.34%), Query Frame = 3
Query: 114 DLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGR--VEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIE-------GCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFI-EGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADR---MNKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMN-----IGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQW------TPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHST-----------GFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDL-KNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPES 2093
D VLL ++++ + ENL+ RF + IYTYIG V+++VNP+K L I+ +I Y+ YE PPHI+A+AD +R M E C++ISGESG+GKT ++K IM YI+ ++ + + +E++K+I+L+SN +LE+FGNA+T RN+NSSRFGKY++I FD G+PIGG I +LLEKSRVV Q + ERNFH FYQ+ G E+D Y Y Q V K+ +D S +K AM+ +G +EQ ++ +VAA+LHLGNV+F E +QA ++K LQ LLGL L + R +A R M K N ++A+ RDAL+KA Y R+F +IV +IN ++ + + IG+LDIYGFEIF N FEQ CINY NEKLQQ+FIEL LK EQ+EY +EG++W + V YFNNK++CDLIE ++ G+ +I+D+ C KVTD + + MD HY S T F I HYAG V Y E F ++N+D L D ++ S + + D++PE + K + T G+ + LV KL +P Y+RCIKPNE K ++ V +QV YLGL EN+ VRRAGYA+R +++F+ RY + +TWP + G G++ ++ + +D + G TK+FI+ P++
Sbjct: 13 DFVLLDEVTKTAFMENLESRFHKERIYTYIGEVVVSVNPYKTLDIYGDDKIQEYKMREMYERPPHIFALADASYRAMKRRSEDTCIMISGESGSGKTEASKIIMRYIAAITNLSKQKEIERVKDILLKSNAILESFGNARTNRNDNSSRFGKYMDIDFDFKGDPIGGHIFNYLLEKSRVVKQQEGERNFHSFYQVPSDSMIGEYGLERDAM---------LYYYTKQGKVPKISTINDSSLYKLNCDAMKSVGFSAEEQKTVWKLVAAILHLGNVVFTHEDHEQAVVENKDVLQIIAKLLGLSHEMLERALCYRVVAARGEVMEKGH------NEKEAYHGRDALAKAAYDRLFSWIVSRINDSIEVRDKKEHGKCTVIGVLDIYGFEIFETNSFEQLCINYCNEKLQQLFIELVLKEEQEEYQREGIEWKSIHRCSQVEYFNNKIICDLIE-QSHKGIIAIMDEGCLNVGKVTDQM---LLQTMDKKLAKHPHYRSRLTDPSDKSMEFHRDFCIKHYAGNVIYSVEEFLDKNKDTLFQDFKRLLYNSKHKSLKDMWPEGQESITKTTQRPATAGTLFKNSMIALVEKLISKRPFYVRCIKPNEIKSPVAFDEKVVGNQVDYLGLLENVRVRRAGYAFRMHYKRFLLRYKMTDAKTWPSYPGQDIDGVREIVDSHGFSD-DVKYGTTKIFIRTPQT 688
BLAST of Myosin IE vs. Ensembl Nematostella
Match: EDO41819 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3A8]) HSP 1 Score: 452.981 bits (1164), Expect = 1.639e-139 Identity = 266/725 (36.69%), Postives = 423/725 (58.34%), Query Frame = 3
Query: 111 DDLVLLPKISQDSITENLKKRFM-DDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIE-GQQQAEFKDKR-SLQFPCYLLGLEESELATKMASREMADRMNKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMN-IGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKD-HYSS---HSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPEN-VTDLKNKRSTL--------------TVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAIL--SKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERA 2210
+DL L + + ++ NL RF+ + IYTY G VL+A+NP+++L ++ + Y+G + + PHI+A+A++ F++M+ D +Q VI+SGESGAGKTVSAK+ M Y S V GGA QI++ ++ +NP++EA GNAKT+RN+NSSRFGKY+EI FDR IG + +LLEKSRVV Q ERN+H+FYQ+ CE + F + PD +SYLNQ VD DD F+ A+ ++G+ DEQL + I++A+LHLGNV ++ G + ++ L+ LLG+++++L + +R++ + + ++ + +A R+A+SK +YS++F ++V+ IN + + IG+LDIYGFE F N FEQFCINY NEKLQQ F + K EQDEYV+E +QW+ +N+++N+ DLIE K G+ +LD+ C K+ D+++ K+ +L K H+S + F I H+A V Y GF E+NRD ++ + + +++ S + + ++F EN KR+ +VGS+ + L+ L PHY+RCIKPN+TK ++ R + Q+ G+ E I + AGY R + +F RY +L SK+ K ++ I+ +++T ++ +Q+GKTK+F + + + LE+ R K +IQ +R K YL++R+ A
Sbjct: 58 NDLTTLSYLHEPAVLHNLNVRFIQSNAIYTYCGIVLVAINPYEELPLYGPDIVAAYRGRSMGDMDPHIFAVAEDAFQSMIRDERNQSVIVSGESGAGKTVSAKYAMRYFSAV-GGASTETQIEKKVIATNPIMEAIGNAKTIRNDNSSRFGKYLEISFDRNHHIIGAHMRTYLLEKSRVVFQAAEERNYHVFYQMCAACELPEMKDFRLAHPDNFSYLNQGDAPVVDSIDDADCFEELREALSMVGINDDEQLMLFRILSAILHLGNVEILQAGDDECTVEENDFHLEMTAVLLGIDKNQLRKWLCNRKI---VTVGEVLIKPLSITEANYGREAISKRIYSQLFKWVVNTINCTLTSTSKPHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFTQHVFKLEQDEYVREEIQWSFINFYDNQPCIDLIEAK--LGILDLLDEEC----KMPKGSDSQWAQKLYKQHLQKSKHFSKPRMSNLAFVIHHFADHVEYFVSGFVEKNRDTVNDEHLALLRASEDEMVGEMFTENDAHSAPRKRAASRAGKQGGKGGKMFKSVGSQFSVSLSKLMETLNSTTPHYVRCIKPNDTKAPFEFHPKRSIQQLRACGVLETIRISAAGYPSRWTYREFFARYIMLLPSKKINRK---KPRETIKLILETFIKDEDMFQMGKTKIFFRAGQ-VAYLEKLRGDKLRRSCVMIQKNYRCYREHKLYLRMRKAA 768
BLAST of Myosin IE vs. Ensembl Nematostella
Match: EDO45563 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RSH2]) HSP 1 Score: 415.231 bits (1066), Expect = 1.255e-129 Identity = 234/681 (34.36%), Postives = 384/681 (56.39%), Query Frame = 3
Query: 111 DDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYEN-PPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELAT---KMASREMADRMNKEQN------IVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAM--AINIDDM----NIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHY----SSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDL-FPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPE 2090
++++ L + + I NL R+ + IYTY+G+VL+AVNP+ I+ I YQ A + PPHIYA + F M + +QCV+ISGESGAGKT S KFI++Y++ VSG R I+E IL++NP+LEAFGNAKT+RN+NSSRFGKY+++ F+ G KI +LLE+SR+V Q NERN+HIFY+++ G ++ +T Y YL+Q + DD E+ AM + ++E I +AAVLHLGN+ F +A+ +D C ++ E A ++ M + ++ I + ++A RDA K LYS++F +IV+KIN ++ DD +IG+LDI+GFE F N FEQ CINY NE LQQ F+ K EQ+EY +EG++W V + +N+ V D++ K P +++D+ + D F+ K++ ++ + H+ S + F + H+AG V Y+ GF ++NR+ S D+++++ S F +++ F E + ++ + T+G + R+ + L+ L C+ ++RC+KPN KK +++ + Q+ Y G+ E + +R++GYA R FE+F+ RY +L +++ + + HL+ T+ + W++G ++F+K+ +
Sbjct: 67 ENMIELGDLDEAGILRNLLIRYRANKIYTYVGSVLVAVNPYCSFPIYGTAYISRYQKAVNATDLPPHIYATGEMSFAMMKREKHNQCVVISGESGAGKTESTKFILQYLTAVSG---RHSTIEEQILDANPILEAFGNAKTIRNDNSSRFGKYIDVHFNDSWVIEGAKIDHYLLEQSRIVAQMPNERNYHIFYRMLAGMSPQEKKSLHLTHAQDYYYLSQGNCLTCEGMDDAYEYDVIRKAMTALWFTEEETQFIFRSIAAVLHLGNISF-----EAKMEDNIE---ACDVMNPETVAAAADLLQVPKEHMEEAFTRKSTFAEGEMIYSPVSVERATDIRDAFVKGLYSKVFIWIVNKINSSIYKPRGKDDTSGRQSIGVLDIFGFEKFDMNSFEQLCINYANENLQQFFVAQIFKNEQEEYDREGIEWNFVTFVDNQEVLDMLAEK-PMNFIALIDEES----RFPQGTDESFLDKLNYNHKDNKHFVRPKSRVQSQFGVVHFAGTVYYDTTGFLDKNRNTFSADLVDLISSSKCNFFLNMFFKERSMGTETRKRSPTLGVQFRRSLDVLMKTLASCRSFFVRCVKPNNYKKPMEFDRELCWQQLRYSGMLETVRIRKSGYAMRHTFEEFVTRYHMLVRDSLRDMSS---RDASHLIATSLLGQENWKLGTKRIFLKESQ 728
BLAST of Myosin IE vs. Ensembl Medaka
Match: myo1f (unconventional myosin-If [Source:NCBI gene;Acc:101170664]) HSP 1 Score: 1145.57 bits (2962), Expect = 0.000e+0 Identity = 582/1114 (52.24%), Postives = 774/1114 (69.48%), Query Frame = 3
Query: 72 HHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRM-NKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELK-NPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPEGFQGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTKP----------GNRDLRAIQAILPTLEKSGIRIKRADTKKVINQTQSFMKSNQQIDRNSTDKLPNLPQSGKAKFPSMSQMRMTPVMGVNPRQSQITDEELVKSVSKNSKRESNITDXXXXXXXXXXXXXXXXVNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 3377
+HWQS+ K S DD+VLL KI++D+I ENLKKR+MDD I+TYIG VLI+VNPFK++ FT +EI +YQGAA YENPPHIYA+ DNM+RNMMID E+QCVIISGESGAGKTV+AK+IM YISKVSGG +V+ +K+IIL+SNPLLEAFGNAKTVRNNNSSRFGKY EIQF RGGEP GGKIS FLLEKSRVV QN+NERNFHI+YQ+IEG +E G+ TPDYY YLNQSG YKVD T+D +F+ T+ AM+V+G+ D Q +L I+A +LHLGNV FIE + + L FP YLLG++ + L K+ SR+M + K ++I + N++QA RDAL+KALY+R+FDY+V+ IN A+ ++ +IG+LDIYGFEIF KNGFEQFCIN+VNEKLQQIFIELTLKAEQ+EYVQEG++WTP++YFNNK+VCDLIE K NPPG+ S+LDDVCAT + D + K+ + +H++S ++GF + HYAGKVSY+ GFCERNRD L D+IE+MQ S FI LFPEN+ K R T T S+I+KQANDLV L KC PHYIRCIKPNETK+ +DWE R QV YLGLRENI VRRAG+AYRR F KF+ RYAIL+ ETWP W G ++G+ HL+++ ++++ Q+Q+G+TK+F+K+PESLFLLEE RERKF+ +A++IQ +R+ A K Y ++RE A+D+ YN KERR++S+NRNF+GDYL L++ P+LR + KRE+V+F+ V K+DRRFK + RDLILT K IYLIGR+K+K+G +KGQ EV+KRK++ +++ ++LS D+F ++ + YDS++E FKTEF+ +LSKRY E+T R + + F + F VK EG+ GG S+ + F T N ++++ T +T+++ GLP ++KP G R+ +A + R RA + Q++ S + R LP L + P+ +Q + ++ ++ + +S+S P V + ALY Y D+DE+S D+IELVRED GWW G+I R G+ P NYV+KI
Sbjct: 4 YHWQSQNVKQSGVDDMVLLSKITEDAIVENLKKRYMDDYIFTYIGPVLISVNPFKQMPYFTDREIELYQGAAQYENPPHIYALTDNMYRNMMIDGENQCVIISGESGAGKTVAAKYIMGYISKVSGGGSKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRVVNQNENERNFHIYYQMIEGANAQQKEALGVMTPDYYYYLNQSGTYKVDGTNDSKDFQETLEAMQVIGIPADIQAQVLQIIAGILHLGNVSFIEAGNYGQVESTDLLAFPAYLLGIDPNRLQDKLTSRQMDSKWGGKSESINVTLNQEQATYTRDALAKALYARLFDYLVEAINKAIQKPHEEFSIGVLDIYGFEIFKKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIKWTPIDYFNNKIVCDLIENKLNPPGIMSVLDDVCATMHAKGEGADGTLLQKLQAAVGTHEHFNSWNSGFVVHHYAGKVSYDINGFCERNRDVLFPDLIELMQSSEFDFIRSLFPENLNTDKKGRPT-TASSKIKKQANDLVNTLMKCTPHYIRCIKPNETKRPKDWEESRARHQVEYLGLRENIRVRRAGFAYRRLFNKFLMRYAILTAETWPCWRGPEQQGVLHLLRSVNMDNDQYQLGRTKVFVKNPESLFLLEEMRERKFDTFARIIQKAWRRFIARKKYEQMREEASDILYNSKERRKNSINRNFVGDYLGLEQRPELRQFLAKRERVDFADSVNKFDRRFKSIKRDLILTPKGIYLIGREKVKKGPEKGQIKEVLKRKMEFESISGVSLSTRQDDFFILHETL-YDSLLESNFKTEFLSLLSKRYEEVTKRKMTISFADRLEFRVKKEGWGGGGSRVLVFQRGTGN-----VAQIKSAGKT-LTITIGDGLPKSSKPTRKSAVGSYGGGRNHVPSRA----HQNGAARGHRAPAPQ---QSEITYSSPNKRGRPPNTALPKLGHQKTPRVPANNQHDQGNLDFLSVPDQGMSGMQRKRSISHRPPPAPKPQ-------------PRPQVPQCRALYQYVGQDSDEISFEVNDVIELVREDPSGWWFGRIRGRQGMFPGNYVEKI 1089
BLAST of Myosin IE vs. Ensembl Medaka
Match: myo1ea (myosin IE [Source:NCBI gene;Acc:101175553]) HSP 1 Score: 1117.06 bits (2888), Expect = 0.000e+0 Identity = 563/1011 (55.69%), Postives = 732/1011 (72.40%), Query Frame = 3
Query: 72 HHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRM-NKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPE--GF-QGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTKPGNRDLRAIQAILPTLEKSGIRIKRADTKKVINQTQSFMKSNQQID-RNSTDKLPNLPQSGKAKFPSMSQMRMTPVMGVNPRQ 3089
+HWQS K + DD+VLL KI++D+I ENLKKR+MDD I+TYIG VLI++NPFK++ F KEI MYQGAA YENPPHIYA+ADNM+RNMMID E+QCVIISGESGAGKTV+AK+IM YIS+VSGG +V+ +K+IIL+SNPLLEAFGNAKT+RNNNSSRFGKY EIQF GGEP GGKIS FLLEKSRVV++N ER+FHIFYQLIEG + + GIT+ DYYSYLNQSG YKVDD +D+S+F+ TMHAM V+G+ +Q +L IVA VLHLGN+ F E A + + L FP +LLG++++ L K+ SR+M + N +++I + N +QA RDALSKAL++R+FDY+V+ IN AM + ++N+G+LDIYGFEIF KNGFEQFCIN+VNEKLQQIFIELTLKAEQ+EYVQEG++WTP++YFNNK+VCDLIE KNPPGV ILDDVCAT V + D + K+ +H++S + GF I HYAGKVSY+ EGFCERNRD L D+IE+MQ S PFI LFPEN+ K R T T GS+I+ QANDLV L KC PHYIRCIKPNETKK +DWE RV QV YLGL+ENI VRRAGYAYRR F KF+ RYAIL+KE+WP W GD ++G++HL+++ ++ Q+Q+G+TK+FIK PESLFLLEE R+RKF+ YA+ IQ +R+ A K Y+++RE A+DL N+KERR HSLNRNF+GDYL +D+ P+LR +GKREK++F+ V KYDRRFK + RD+ILT K +YLIGR+K+KQG +KGQ +EV+KR++D+ + ++LS D+F+++ +EYDS++E FKTEFI +L+KR+ E T + L LKF+ + +K E GF GG+S+++ F + + ++ S ++ VS+ GLP NT+P R + + + A V +Q +N + RNS P SG ++ PV+ NP Q
Sbjct: 9 YHWQSHNVKLTGVDDMVLLTKINEDAIVENLKKRYMDDYIFTYIGPVLISINPFKQMPYFGDKEIEMYQGAAQYENPPHIYALADNMYRNMMIDRENQCVIISGESGAGKTVAAKYIMGYISRVSGGGPKVQHVKDIILQSNPLLEAFGNAKTLRNNNSSRFGKYFEIQFSSGGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGAGAEQKNSLGITSLDYYSYLNQSGSYKVDDINDRSDFQETMHAMGVIGIAPADQSMVLQIVAGVLHLGNITFKEAGNYAAVESEEFLAFPAFLLGIDQNRLKEKITSRKMDSKWGNTKESIDVTLNVEQACYTRDALSKALHARVFDYLVESINKAMVKDHQELNVGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIKWTPIDYFNNKIVCDLIESKNPPGVMCILDDVCATMHAVGEGADQTMLQKLRVQINTHEHFNSWNQGFIIHHYAGKVSYDAEGFCERNRDVLFTDLIELMQSSETPFIRALFPENLKADKKGRPT-TAGSKIKIQANDLVSTLMKCTPHYIRCIKPNETKKPKDWEESRVKHQVEYLGLKENIRVRRAGYAYRRVFRKFLNRYAILTKESWPSWRGDEREGVRHLLRSVQMDQDQFQLGRTKVFIKAPESLFLLEETRDRKFDGYARTIQKAWRKHVARKKYVQMREEASDLLLNRKERRRHSLNRNFVGDYLGMDDRPELRQFLGKREKIDFADKVTKYDRRFKGIKRDMILTPKSVYLIGREKVKQGPEKGQVMEVLKRQIDVGKILAVSLSTMQDDFMILH-EQEYDSLLECIFKTEFISLLAKRFEEKTQKKLPLKFNNTLEMKLKKENWGFLSGGNSRQVEF-IHGRGDIPELKPS-----SKSLQVSIGPGLPKNTRP-TRKSFSQSRSSVSRTNHHTPSRSAPGPPVSHQNGGLRNTNHVANQRNSHHHNQRHPSSGSSR----------PVLPSNPNQ 1000
BLAST of Myosin IE vs. Ensembl Medaka
Match: myo1ea (myosin IE [Source:NCBI gene;Acc:101175553]) HSP 1 Score: 1108.59 bits (2866), Expect = 0.000e+0 Identity = 546/928 (58.84%), Postives = 706/928 (76.08%), Query Frame = 3
Query: 72 HHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRM-NKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPE--GF-QGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTK 2843
+HWQS K + DD+VLL KI++D+I ENLKKR+MDD I+TYIG VLI++NPFK++ F KEI MYQGAA YENPPHIYA+ADNM+RNMMID E+QCVIISGESGAGKTV+AK+IM YIS+VSGG +V+ +K+IIL+SNPLLEAFGNAKT+RNNNSSRFGKY EIQF GGEP GGKIS FLLEKSRVV++N ER+FHIFYQLIEG + + GIT+ DYYSYLNQSG YKVDD +D+S+F+ TMHAM V+G+ +Q +L IVA VLHLGN+ F E A + + L FP +LLG++++ L K+ SR+M + N +++I + N +QA RDALSKAL++R+FDY+V+ IN AM + ++N+G+LDIYGFEIF KNGFEQFCIN+VNEKLQQIFIELTLKAEQ+EYVQEG++WTP++YFNNK+VCDLIE KNPPGV ILDDVCAT V + D + K+ +H++S + GF I HYAGKVSY+ EGFCERNRD L D+IE+MQ S PFI LFPEN+ K R T T GS+I+ QANDLV L KC PHYIRCIKPNETKK +DWE RV QV YLGL+ENI VRRAGYAYRR F KF+ RYAIL+KE+WP W GD ++G++HL+++ ++ Q+Q+G+TK+FIK PESLFLLEE R+RKF+ YA+ IQ +R+ A K Y+++RE A+DL N+KERR HSLNRNF+GDYL +D+ P+LR +GKREK++F+ V KYDRRFK + RD+ILT K +YLIGR+K+KQG +KGQ +EV+KR++D+ + ++LS D+F+++ +EYDS++E FKTEFI +L+KR+ E T + L LKF+ + +K E GF GG+S+++ F + + ++ S ++ VS+ GLP NT+
Sbjct: 13 YHWQSHNVKLTGVDDMVLLTKINEDAIVENLKKRYMDDYIFTYIGPVLISINPFKQMPYFGDKEIEMYQGAAQYENPPHIYALADNMYRNMMIDRENQCVIISGESGAGKTVAAKYIMGYISRVSGGGPKVQHVKDIILQSNPLLEAFGNAKTLRNNNSSRFGKYFEIQFSSGGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGAGAEQKNSLGITSLDYYSYLNQSGSYKVDDINDRSDFQETMHAMGVIGIAPADQSMVLQIVAGVLHLGNITFKEAGNYAAVESEEFLAFPAFLLGIDQNRLKEKITSRKMDSKWGNTKESIDVTLNVEQACYTRDALSKALHARVFDYLVESINKAMVKDHQELNVGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIKWTPIDYFNNKIVCDLIESKNPPGVMCILDDVCATMHAVGEGADQTMLQKLRVQINTHEHFNSWNQGFIIHHYAGKVSYDAEGFCERNRDVLFTDLIELMQSSETPFIRALFPENLKADKKGRPT-TAGSKIKIQANDLVSTLMKCTPHYIRCIKPNETKKPKDWEESRVKHQVEYLGLKENIRVRRAGYAYRRVFRKFLNRYAILTKESWPSWRGDEREGVRHLLRSVQMDQDQFQLGRTKVFIKAPESLFLLEETRDRKFDGYARTIQKAWRKHVARKKYVQMREEASDLLLNRKERRRHSLNRNFVGDYLGMDDRPELRQFLGKREKIDFADKVTKYDRRFKGIKRDMILTPKSVYLIGREKVKQGPEKGQVMEVLKRQIDVGKILAVSLSTMQDDFMILH-EQEYDSLLECIFKTEFISLLAKRFEEKTQKKLPLKFNNTLEMKLKKENWGFLSGGNSRQVEF-IHGRGDIPELKPS-----SKSLQVSIGPGLPKNTR 932 HSP 2 Score: 72.7886 bits (177), Expect = 1.924e-12 Identity = 30/56 (53.57%), Postives = 41/56 (73.21%), Query Frame = 3
Query: 3210 VNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 3377
V + +ALYAY+A DTDELS D+IE+++ED GWW G++ + GL P+NYV KI
Sbjct: 972 VPQCKALYAYDAQDTDELSFNADDVIEIIKEDASGWWMGRLRGKQGLFPNNYVTKI 1027
BLAST of Myosin IE vs. Ensembl Medaka
Match: myo1ea (myosin IE [Source:NCBI gene;Acc:101175553]) HSP 1 Score: 1042.72 bits (2695), Expect = 0.000e+0 Identity = 542/1024 (52.93%), Postives = 717/1024 (70.02%), Query Frame = 3
Query: 330 MFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRM-NKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPE--GF-QGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTKPGNRDLRAIQAILPTLEKSGIRIKRADTKKVINQTQSFMKSNQQID-RNSTDKLPNLPQSGKAK--FPS-MSQMRMTPVMGVNPRQSQITDEELVKSVSKNSKRESNITDXXXXXXXXXXXXXXXXVNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 3377
M+RNMMID E+QCVIISGESGAGKTV+AK+IM YIS+VSGG +V+ +K+IIL+SNPLLEAFGNAKT+RNNNSSRFGKY EIQF GGEP GGKIS FLLEKSRVV++N ER+FHIFYQLIEG + + GIT+ DYYSYLNQSG YKVDD +D+S+F+ TMHAM V+G+ +Q +L IVA VLHLGN+ F E A + + L FP +LLG++++ L K+ SR+M + N +++I + N +QA RDALSKAL++R+FDY+V+ IN AM + ++N+G+LDIYGFEIF KNGFEQFCIN+VNEKLQQIFIELTLKAEQ+EYVQEG++WTP++YFNNK+VCDLIE KNPPGV ILDDVCAT V + D + K+ +H++S + GF I HYAGKVSY+ EGFCERNRD L D+IE+MQ S PFI LFPEN+ K R T T GS+I+ QANDLV L KC PHYIRCIKPNETKK +DWE RV QV YLGL+ENI VRRAGYAYRR F KF+ RYAIL+KE+WP W GD ++G++HL+++ ++ Q+Q+G+TK+FIK PESLFLLEE R+RKF+ YA+ IQ +R+ A K Y+++RE A+DL N+KERR HSLNRNF+GDYL +D+ P+LR +GKREK++F+ V KYDRRFK + RD+ILT K +YLIGR+K+KQG +KGQ +EV+KR++D+ + ++LS D+F+++ +EYDS++E FKTEFI +L+KR+ E T + L LKF+ + +K E GF GG+S+++ F + + ++ S ++ VS+ GLP NT+P R + + + A V +Q +N + RNS P SG ++ PS +Q+R G + Q + + + + R S G +P +P V + +ALYAY+A DTDELS D+IE+++ED GWW G++ + GL P+NYV KI
Sbjct: 1 MYRNMMIDRENQCVIISGESGAGKTVAAKYIMGYISRVSGGGPKVQHVKDIILQSNPLLEAFGNAKTLRNNNSSRFGKYFEIQFSSGGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGAGAEQKNSLGITSLDYYSYLNQSGSYKVDDINDRSDFQETMHAMGVIGIAPADQSMVLQIVAGVLHLGNITFKEAGNYAAVESEEFLAFPAFLLGIDQNRLKEKITSRKMDSKWGNTKESIDVTLNVEQACYTRDALSKALHARVFDYLVESINKAMVKDHQELNVGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIKWTPIDYFNNKIVCDLIESKNPPGVMCILDDVCATMHAVGEGADQTMLQKLRVQINTHEHFNSWNQGFIIHHYAGKVSYDAEGFCERNRDVLFTDLIELMQSSETPFIRALFPENLKADKKGRPT-TAGSKIKIQANDLVSTLMKCTPHYIRCIKPNETKKPKDWEESRVKHQVEYLGLKENIRVRRAGYAYRRVFRKFLNRYAILTKESWPSWRGDEREGVRHLLRSVQMDQDQFQLGRTKVFIKAPESLFLLEETRDRKFDGYARTIQKAWRKHVARKKYVQMREEASDLLLNRKERRRHSLNRNFVGDYLGMDDRPELRQFLGKREKIDFADKVTKYDRRFKGIKRDMILTPKSVYLIGREKVKQGPEKGQVMEVLKRQIDVGKILAVSLSTMQDDFMILH-EQEYDSLLECIFKTEFISLLAKRFEEKTQKKLPLKFNNTLEMKLKKENWGFLSGGNSRQVEF-IHGRGDIPELKPS-----SKSLQVSIGPGLPKNTRP-TRKSFSQSRSSVSRTNHHTPSRSAPGPPVSHQNGGLRNTNHVANQRNSHHHNQRHPSSGSSRPVLPSNPNQLRER---GSSRPQPNLDCLRVPDQGAAGAHRPSVSRPAPGGGRPKPAPKPKPQVPQCKALYAYDAQDTDELSFNADDVIEIIKEDASGWWMGRLRGKQGLFPNNYVTKI 1012
BLAST of Myosin IE vs. Ensembl Medaka
Match: myo1ea (myosin IE [Source:NCBI gene;Acc:101175553]) HSP 1 Score: 1041.57 bits (2692), Expect = 0.000e+0 Identity = 544/1041 (52.26%), Postives = 720/1041 (69.16%), Query Frame = 3
Query: 330 MFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRM-NKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPE--GF-QGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTKP--------------GNRDLRAIQAILPTL--EKSGIRIKRADTKKVINQTQSFMKSNQQIDRNSTDK-LPNLPQSGKAKFPSMSQMRM----TPVMGVNPRQSQITDEELVKSVSKNSKRESNITDXXXXXXXXXXXXXXXXVNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 3377
M+RNMMID E+QCVIISGESGAGKTV+AK+IM YIS+VSGG +V+ +K+IIL+SNPLLEAFGNAKT+RNNNSSRFGKY EIQF GGEP GGKIS FLLEKSRVV++N ER+FHIFYQLIEG + + GIT+ DYYSYLNQSG YKVDD +D+S+F+ TMHAM V+G+ +Q +L IVA VLHLGN+ F E A + + L FP +LLG++++ L K+ SR+M + N +++I + N +QA RDALSKAL++R+FDY+V+ IN AM + ++N+G+LDIYGFEIF KNGFEQFCIN+VNEKLQQIFIELTLKAEQ+EYVQEG++WTP++YFNNK+VCDLIE KNPPGV ILDDVCAT V + D + K+ +H++S + GF I HYAGKVSY+ EGFCERNRD L D+IE+MQ S PFI LFPEN+ K R T T GS+I+ QANDLV L KC PHYIRCIKPNETKK +DWE RV QV YLGL+ENI VRRAGYAYRR F KF+ RYAIL+KE+WP W GD ++G++HL+++ ++ Q+Q+G+TK+FIK PESLFLLEE R+RKF+ YA+ IQ +R+ A K Y+++RE A+DL N+KERR HSLNRNF+GDYL +D+ P+LR +GKREK++F+ V KYDRRFK + RD+ILT K +YLIGR+K+KQG +KGQ +EV+KR++D+ + ++LS D+F+++ +EYDS++E FKTEFI +L+KR+ E T + L LKF+ + +K E GF GG+S+++ F + + ++ S ++ VS+ GLP NT+P N + A P + + G+R +T V NQ S + + S+ LP+ P + + S Q + P G + D + + + R S G +P +P V + +ALYAY+A DTDELS D+IE+++ED GWW G++ + GL P+NYV KI
Sbjct: 1 MYRNMMIDRENQCVIISGESGAGKTVAAKYIMGYISRVSGGGPKVQHVKDIILQSNPLLEAFGNAKTLRNNNSSRFGKYFEIQFSSGGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGAGAEQKNSLGITSLDYYSYLNQSGSYKVDDINDRSDFQETMHAMGVIGIAPADQSMVLQIVAGVLHLGNITFKEAGNYAAVESEEFLAFPAFLLGIDQNRLKEKITSRKMDSKWGNTKESIDVTLNVEQACYTRDALSKALHARVFDYLVESINKAMVKDHQELNVGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIKWTPIDYFNNKIVCDLIESKNPPGVMCILDDVCATMHAVGEGADQTMLQKLRVQINTHEHFNSWNQGFIIHHYAGKVSYDAEGFCERNRDVLFTDLIELMQSSETPFIRALFPENLKADKKGRPT-TAGSKIKIQANDLVSTLMKCTPHYIRCIKPNETKKPKDWEESRVKHQVEYLGLKENIRVRRAGYAYRRVFRKFLNRYAILTKESWPSWRGDEREGVRHLLRSVQMDQDQFQLGRTKVFIKAPESLFLLEETRDRKFDGYARTIQKAWRKHVARKKYVQMREEASDLLLNRKERRRHSLNRNFVGDYLGMDDRPELRQFLGKREKIDFADKVTKYDRRFKGIKRDMILTPKSVYLIGREKVKQGPEKGQVMEVLKRQIDVGKILAVSLSTMQDDFMILH-EQEYDSLLECIFKTEFISLLAKRFEEKTQKKLPLKFNNTLEMKLKKENWGFLSGGNSRQVEF-IHGRGDIPELKPS-----SKSLQVSIGPGLPKNTRPTRKSFSQSRSSVSRTNHHTPSRSAPGPPVSHQNGGLR----NTNHVANQRNSHHHNQRHPSSGSSRPVLPSNPNQLRERGSSRPQPNLDCLRVPDQGAAGSGGRRPD-----ANGEMAHRPSVSRPAPGGGRPKPAPKPKPQVPQCKALYAYDAQDTDELSFNADDVIEIIKEDASGWWMGRLRGKQGLFPNNYVTKI 1024
BLAST of Myosin IE vs. Planmine SMEST
Match: SMESG000068232.1 (SMESG000068232.1) HSP 1 Score: 2215.65 bits (5740), Expect = 0.000e+0 Identity = 1100/1103 (99.73%), Postives = 1101/1103 (99.82%), Query Frame = 3
Query: 69 MHHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRMNKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPEGFQGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTKPGNRDLRAIQAILPTLEKSGIRIKRADTKKVINQTQSFMKSNQQIDRNSTDKLPNLPQSGKAKFPSMSQMRMTPVMGVNPRQSQITDEELVKSVSKNSKRESNITDXXXXXXXXXXXXXXXXVNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 3377
MHHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRMNKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFV KMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESLFLLEERRERKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPEGFQGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTKPGNRDLRAIQAILPTLEKSGIRIKRA+TKKVINQTQSFMKSNQQIDRNSTDKLPNLPQSGKAKFPSMSQMRMTPVMGVNPRQSQITDEELVKSVSKNSKRESNI DKKGPPKPPRPTRPARPVNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI
Sbjct: 1 MHHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRMNKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVAKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPESLFLLEERRERKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYNKKERREHSLNRNFIGDYLFLDENPQLRILIGKREKVEFSSFVWKYDRRFKKLGRDLILTDKFIYLIGRDKIKQGEKKGQFIEVIKRKLDISALNCITLSPYFDNFVVISVSKEYDSVIEIEFKTEFIMVLSKRYNEITNRNLQLKFDTVINFTVKPEGFQGGSSKKITFTVATQNKTCDVASKVQGLLSTAMTVSVPRGLPSNTKPGNRDLRAIQAILPTLEKSGIRIKRANTKKVINQTQSFMKSNQQIDRNSTDKLPNLPQSGKAKFPSMSQMRMTPVMGVNPRQSQITDEELVKSVSKNSKRESNIIDKKGPPKPPRPTRPARPVNRVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 1103
BLAST of Myosin IE vs. Planmine SMEST
Match: SMESG000051401.1 (SMESG000051401.1) HSP 1 Score: 528.865 bits (1361), Expect = 1.978e-169 Identity = 302/747 (40.43%), Postives = 449/747 (60.11%), Query Frame = 3
Query: 114 DLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGR--VEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITT-PDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLF-----------IEGQQQA-EFKDKR--SLQFPCYLLGLEESELATKMASREMADRMNKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAINIDDMN------------IGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSS-----------HSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENVTDL-KNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADI-NDGQWQIGKTKLFIKDPESXXXXXXXXXXKFNHYAKVIQIFFRQVNATKHYLKLRERAADLFYN 2228
D +L+ I S +NL+KRF+ + IYTYIG VL+AVNP+K+L+I++ KE+ Y+G YE+PPHI+AIAD + + + C++ISGESG+GKT ++K I+ YI++V+ +G+ +E++K ++L+SN +LE FGNAKT RN+NSSRFGKY++I FD G+P+GG ++ +LLEKSRVV+Q ER+FH FYQL+ G D + FG+ PD Y Y+NQ KV +DK+ ++ + A+ +G K E +I ++VAA+LHLG V F I+G ++ + D S++ L + E+ L ++ R +A R + I+ + A ARDA +KA+Y R+F +I KIN + I+ D IG+LDIYGFEIF N FEQFCINY NEKLQQ+FI+L LK EQ+EY++EG++WT + YFNN+ +CD++EL G+F+ILDD C +VTD + F+ +D + K Y S H F I HYAG+V+Y GF E+N+D D ++ S N + ++ + + + + ++VG+ + LV L K PHY+RCIKPN K + + V Q YLGL EN+ VRRAG+A R + +F+QR+ +LSK+TWP W ++K+G + ++ I D QW G TK+FI+ +S+F LE+ R + ++Q +R V A + L R RAA+ N
Sbjct: 14 DFILVDNIDLKSFVDNLEKRFIKNRIYTYIGEVLVAVNPYKELNIYSNKEVNEYKGRELYESPPHIFAIADAAHKIVKRQNQDTCIVISGESGSGKTEASKIILRYIAQVTNISGQDEIERVKNLLLKSNCILECFGNAKTNRNDNSSRFGKYMDIHFDFKGDPVGGIMNNYLLEKSRVVMQQVGERSFHSFYQLLYGAPSDRLKEFGLQNDPDKYCYINQGNNSKVPSINDKARYQEVIEAINAIGFTKLESKTIWNLVAAILHLGTVQFELNESSSQNSSIQGATESVKITDSSIPSIKHMAELFDVSEAGLTKALSERAVAARGDV---IMKGHTMELATYARDAFAKAIYDRLFSWIFAKINEKIKISDKDSRENDLSNHNKFSVIGVLDIYGFEIFENNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYMREGIKWTNIEYFNNQEICDMVELPR-LGIFAILDDNCIKPGRVTDQM---FLEDLDSNLQKKSFYKSRKLFPTEKTIEHERDFRIDHYAGQVTYNVNGFLEKNKDAFFEDFKRLLYNSNNNTVKSMWLDGAKSVSETTQRPMSVGANFKTSIQKLVENLAKKIPHYVRCIKPNGIKSPGRLDIELVQHQTRYLGLIENVRVRRAGFATRMEYARFLQRFKMLSKKTWPSWNSNLKEGSKAIIDDMGILEDVQW--GHTKIFIRSAQSIFKLEQARTCAVDWIVVILQKRWRGVLARR--LAKRIRAANKIVN 749
BLAST of Myosin IE vs. Planmine SMEST
Match: SMESG000005090.1 (SMESG000005090.1) HSP 1 Score: 446.047 bits (1146), Expect = 4.762e-132 Identity = 257/681 (37.74%), Postives = 379/681 (55.65%), Query Frame = 3
Query: 108 ADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFI----EGQQQAEFKDKRSLQFPCYLLGLEESELATKMASREMADRMNKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAM-----------AINIDD----MNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENV-TDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPE 2090
DD++ L +++ I NL R+ + IYTY G +L+AVNP+ L I+T KEI Y+ + PHI+AIADN + NM Q +IISGESGAGKT S K I+++++ VSG +EQ +L+SNP+LEAFGNAKT+RN+NSSRFGKY++I F G G KI QFLLEKSR+V Q ++ERN+H+FY ++EG + R FG+ D+Y+YLNQ G + T D +F AM+V+ +DE I ++AA LHLGN+ F E F LL L+ +L + ++ + R + +V + Q RDAL K +Y R+F +IV+KIN A+ A+N +IG+LDI+GFE F N FEQ CINY NE LQQ F+ K EQ+EY E + W +++ +N+ DLI +KN + +++D+ S+ NK V + F I H+AG V Y+ +GF E+NRD + D++E++Q + + F+ LF ++ ++ T+G + RK + L+ L + +P ++RCIKPNE KK D++ + Q+ Y G+ E I +R+AGY R F F+ RY IL + + L+ ++ +QIGKTKLF+KD +
Sbjct: 67 VDDMISLGDLNEAGILRNLLIRYKRNEIYTYTGRILVAVNPYAVLPIYTPKEIKNYKNCKIGDLSPHIFAIADNAYNNMRRVSRDQSIIISGESGAGKTESTKLILQFLAAVSGQHSWIEQQ---VLDSNPILEAFGNAKTIRNDNSSRFGKYIDIYFGVNGAIEGAKIDQFLLEKSRIVSQMRDERNYHVFYCMLEGLPIETRSRFGLRASDHYAYLNQGGRIDLTGTTDIVDFPTLHSAMKVLTFTEDECQEIFQLLAAFLHLGNINFKAKLERNMDSCEVSMDSEFNFASKLLQLDSEDLRKALTTKNIITR---DDFVVTNVSIAQGINIRDALVKGIYGRLFVWIVEKINTAIYRPSLSQVPKSALNAKSNSKYTSIGVLDIFGFENFDNNSFEQLCINYANENLQQFFVRHIFKMEQEEYAAELIDWQHISFTDNQETLDLIGVKN-CNILALIDEESRFPKGTDHSLLNKLVNTCSKHPRFIKQKADIVKIFGIEHFAGVVHYQIDGFLEKNRDFFNADLMELIQTTKSQFLKILFEKDFKMGFDTRKRAPTLGMQFRKSLDSLMKILMEREPFFVRCIKPNEFKKKLDFDRSLCLRQLRYSGMMETIRIRKAGYPIRHEFPDFIDRYRILVPGIPSSFRCKDTRETTKLVCKNILDPKGYQIGKTKLFLKDAQ 740
BLAST of Myosin IE vs. Planmine SMEST
Match: SMESG000005090.1 (SMESG000005090.1) HSP 1 Score: 445.662 bits (1145), Expect = 5.026e-132 Identity = 257/681 (37.74%), Postives = 381/681 (55.95%), Query Frame = 3
Query: 108 ADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQIKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQ----AEFKDKRSLQFPCYLLGLEESELATKMASREMADRMNKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAM-----------AINIDD----MNIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYSSHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPENV-TDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQRYAILSKETWPKWTGDVKKGIQHLMKTADINDGQWQIGKTKLFIKDPE 2090
DD++ L +++ I NL R+ + IYTY G +L+AVNP+ L I+T KEI Y+ + PHI+AIADN + NM Q +IISGESGAGKT S K I+++++ VSG +EQ +L+SNP+LEAFGNAKT+RN+NSSRFGKY++I F G G KI QFLLEKSR+V Q ++ERN+H+FY ++EG + R FG+ D+Y+YLNQ G + T D +F AM+V+ +DE I ++AA LHLGN+ F ++ E F LL L+ +L + ++ + R + +V + Q RDAL K +Y R+F +IV+KIN A+ A+N +IG+LDI+GFE F N FEQ CINY NE LQQ F+ K EQ+EY E + W +++ +N+ DLI +KN + +++D+ S+ NK V + F I H+AG V Y+ +GF E+NRD + D++E++Q + + F+ LF ++ ++ T+G + RK + L+ L + +P ++RCIKPNE KK D++ + Q+ Y G+ E I +R+AGY R F F+ RY IL + + L+ ++ +QIGKTKLF+KD +
Sbjct: 67 VDDMISLGDLNEAGILRNLLIRYKRNEIYTYTGRILVAVNPYAVLPIYTPKEIKNYKNCKIGDLSPHIFAIADNAYNNMRRVSRDQSIIISGESGAGKTESTKLILQFLAAVSGQHSWIEQQ---VLDSNPILEAFGNAKTIRNDNSSRFGKYIDIYFGVNGAIEGAKIDQFLLEKSRIVSQMRDERNYHVFYCMLEGLPIETRSRFGLRASDHYAYLNQGGRIDLTGTTDIVDFPTLHSAMKVLTFTEDECQEIFQLLAAFLHLGNINFKAKLERNMDSCEVSMDSEFNFASKLLQLDSEDLRKALTTKNIITR---DDFVVTNVSIAQGINIRDALVKGIYGRLFVWIVEKINTAIYRPSLSQVPKSALNAKSNSKYTSIGVLDIFGFENFDNNSFEQLCINYANENLQQFFVRHIFKMEQEEYAAELIDWQHISFTDNQETLDLIGVKN-CNILALIDEESRFPKGTDHSLLNKLVNTCSKHPRFIKQKADIVKIFGIEHFAGVVHYQIDGFLEKNRDFFNADLMELIQTTKSQFLKILFEKDFKMGFDTRKRAPTLGMQFRKSLDSLMKILMEREPFFVRCIKPNEFKKKLDFDRSLCLRQLRYSGMMETIRIRKAGYPIRHEFPDFIDRYRILVPGIPSSFRCKDTRETTKLVCKNILDPKGYQIGKTKLFLKDAQ 740
BLAST of Myosin IE vs. Planmine SMEST
Match: SMESG000061386.1 (SMESG000061386.1) HSP 1 Score: 419.853 bits (1078), Expect = 4.777e-123 Identity = 249/696 (35.78%), Postives = 387/696 (55.60%), Query Frame = 3
Query: 111 DDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIAVNPFKKLSIFTQKEIGMYQGAATYENPPHIYAIADNMFRNMMIDYESQCVIISGESGAGKTVSAKFIMEYISKVSGGAGRVEQ--------IKEIILESNPLLEAFGNAKTVRNNNSSRFGKYVEIQFDRGGEPIGGKISQFLLEKSRVVLQNQNERNFHIFYQLIEGCEKDIREMFGITTPDYYSYLNQSGVYKVDDTDDKSEFKNTMHAMEVMGLEKDEQLSILSIVAAVLHLGNVLFIEGQQQAEFKDKRSLQFPCYLLGLEESEL--ATKMASREMADRMNKEQNIVILFNRQQAFQARDALSKALYSRMFDYIVDKINVAMAIN---------IDDM---------NIGILDIYGFEIFVKNGFEQFCINYVNEKLQQIFIELTLKAEQDEYVQEGVQWTPVNYFNNKVVCDLIELKNPPGVFSILDDVCATAFKVTDSIDNKFVTKMDGSNLNKDHYS----SHSTGFTIFHYAGKVSYECEGFCERNRDQLSVDVIEMMQKSTNPFIVDLFPE----NVTDLKNKRSTLTVGSRIRKQANDLVVKLTKCQPHYIRCIKPNETKKARDWENDRVVDQVTYLGLRENIIVRRAGYAYRRPFEKFMQR-YAILSKETWPKWTGDVKKGIQHLM-KTADINDGQWQIGKTKLFIKD 2084
D++ L ++S S+ NL+ R+ IYTYIG++LI++NP+ +L I+ +K I YQ + PPH++ I + + MM D E+Q ++ISGESGAGKT S K +++Y + VSGG V+Q I IL+S PLLE+FGNA+T+RN+NSSRFGKYVEI FD G G +I+ +LLEKSR+V N ER +HIFY+++ G + + + YSYLN S + + D +D + K M + +GL ++ + I++AVLHLGN+ F+E Q+ + + ++ +L +++ L M + E K+ +I L N++Q+ RD LSK LYS +F++IV K+N + N +D +I +LDIYGFE F N EQ CINY NE LQQ F + EQ+EY +EG+ W ++Y +N+ + DL+ K P G+ IL+D C+ + D F+ K + D+Y +H F I H+AG +SY GF E+NRD L +++ +++ I +F + + K T V + L+ K+ CQP +IRC+KPN TK+A + D V+DQ+ Y G+ E + +R++G+ + F F+ R Y +++KE D + LM K + + +++GKTKLF+K+
Sbjct: 15 DNMTNLVELSDQSLLSNLQVRYAQKLIYTYIGSILISINPYTELGIYDKKYIVSYQNKLIQDMPPHLFGIGETNYTKMMRDNENQVIVISGESGAGKTESFKRLLKYFAFVSGGFKEVKQNSDQLSSDIATRILDSTPLLESFGNAQTIRNDNSSRFGKYVEIFFDNGNI-CGSRITNYLLEKSRIVNINPRERGYHIFYEVLLGLDSFNKSQYYFKGIKDYSYLNNSKEFTIKDRNDAANLKEFMSQWDSLGLTSEDLDVAMRILSAVLHLGNIKFMEEQETSYLVETENIGIVSKMLKVDQDSLKHCLTMKTTETV----KDASISPL-NKEQSINYRDTLSKHLYSELFNWIVTKVNTGLNQNNLIVRRQSVVDRSLLSAGSNFRSIAMLDIYGFENFPDNSLEQLCINYANETLQQFFNRYVFELEQEEYKKEGISWHYISYPDNQPIIDLLSAK-PNGIIQILNDECS----IPQGSDVSFLNKCHNVHGKNDNYEKPKKTHPPQFIIHHFAGNISYSVAGFLEKNRDVLRKEILNVIENCEVVEIATIFRKKRELQTKNPTAKARTPAVMGDFQSSLTTLLAKMKTCQPWFIRCLKPNTTKEALKFNKDIVMDQMKYTGILETVKIRKSGFPIQILFSVFLSRFYLLVTKEIRKASLTDQQAACLKLMIKFKGVKNKHFELGKTKLFLKE 699 The following BLAST results are available for this feature:
BLAST of Myosin IE vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Myosin IE vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Myosin IE vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Myosin IE vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Myosin IE vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Myosin IE vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Myosin IE vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Myosin IE vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Myosin IE vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Myosin IE vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Myosin IE vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Myosin IE vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Myosin IE vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Myosin IE vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30020872 ID=SMED30020872|Name=Myosin IE|organism=Schmidtea mediterranea sexual|type=transcript|length=3479bpback to top protein sequence of SMED30020872-orf-1 >SMED30020872-orf-1 ID=SMED30020872-orf-1|Name=SMED30020872-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1104bp MHHWQSKTTKNSTADDLVLLPKISQDSITENLKKRFMDDCIYTYIGNVLIback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
|
