Sorting nexin, putative

Overview
NameSorting nexin, putative
Smed IDSMED30020813
Length (bp)944
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Sorting nexin, putative (SMED30020813) t-SNE clustered cells

Violin plots show distribution of expression levels for Sorting nexin, putative (SMED30020813) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Sorting nexin, putative (SMED30020813) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Sorting nexin, putative (SMED30020813) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30020813

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parenchymaSMED30020813 dd_Smed_v4_3377_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30020813 dd_Smed_v4_3377_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Human
Match: SNX12 (sorting nexin 12 [Source:HGNC Symbol;Acc:HGNC:14976])

HSP 1 Score: 223.016 bits (567), Expect = 9.793e-73
Identity = 119/155 (76.77%), Postives = 136/155 (87.74%), Query Frame = 3 
Query:  117 AVTSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKVR 581
            A T RL  K Q + DAY PP+NFLEID+  PQT GVG+ R+TTYEVR+ TNLP+FK K+S VRRRYSDFEWL++ELERDSKIVVP LPGKA KRQLPFRGD+GIF+E FIEERR+GLE+F+NKIAGHPLAQNE+CLHMFLQ+E IDRNYVPGKVR
Sbjct:    7 ADTRRLNSKPQDLTDAYGPPSNFLEIDIFNPQTVGVGRARFTTYEVRMRTNLPIFKLKESCVRRRYSDFEWLKNELERDSKIVVPPLPGKALKRQLPFRGDEGIFEESFIEERRQGLEQFINKIAGHPLAQNERCLHMFLQEEAIDRNYVPGKVR 161
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Human
Match: SNX12 (sorting nexin 12 [Source:HGNC Symbol;Acc:HGNC:14976])

HSP 1 Score: 223.016 bits (567), Expect = 9.793e-73
Identity = 119/155 (76.77%), Postives = 136/155 (87.74%), Query Frame = 3 
Query:  117 AVTSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKVR 581
            A T RL  K Q + DAY PP+NFLEID+  PQT GVG+ R+TTYEVR+ TNLP+FK K+S VRRRYSDFEWL++ELERDSKIVVP LPGKA KRQLPFRGD+GIF+E FIEERR+GLE+F+NKIAGHPLAQNE+CLHMFLQ+E IDRNYVPGKVR
Sbjct:    7 ADTRRLNSKPQDLTDAYGPPSNFLEIDIFNPQTVGVGRARFTTYEVRMRTNLPIFKLKESCVRRRYSDFEWLKNELERDSKIVVPPLPGKALKRQLPFRGDEGIFEESFIEERRQGLEQFINKIAGHPLAQNERCLHMFLQEEAIDRNYVPGKVR 161
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Human
Match: SNX3 (sorting nexin 3 [Source:HGNC Symbol;Acc:HGNC:11174])

HSP 1 Score: 218.779 bits (556), Expect = 3.874e-71
Identity = 115/155 (74.19%), Postives = 138/155 (89.03%), Query Frame = 3 
Query:  117 AVTSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKVR 581
            A T RL  K Q + DAY PP+NFLEID+S PQT GVG+GR+TTYE+R+ TNLP+FK K+STVRRRYSDFEWLRSELER+SK+VVP LPGKA+ RQLPFRGDDGIFD++FIEER++GLE+F+NK+AGHPLAQNE+CLHMFLQDE ID++Y P K+R
Sbjct:    6 ADTRRLITKPQNLNDAYGPPSNFLEIDVSNPQTVGVGRGRFTTYEIRVKTNLPIFKLKESTVRRRYSDFEWLRSELERESKVVVPPLPGKAFLRQLPFRGDDGIFDDNFIEERKQGLEQFINKVAGHPLAQNERCLHMFLQDEIIDKSYTPSKIR 160
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Human
Match: SNX12 (sorting nexin 12 [Source:HGNC Symbol;Acc:HGNC:14976])

HSP 1 Score: 218.779 bits (556), Expect = 6.484e-71
Identity = 117/153 (76.47%), Postives = 134/153 (87.58%), Query Frame = 3 
Query:  117 AVTSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGK 575
            A T RL  K Q + DAY PP+NFLEID+  PQT GVG+ R+TTYEVR+ TNLP+FK K+S VRRRYSDFEWL++ELERDSKIVVP LPGKA KRQLPFRGD+GIF+E FIEERR+GLE+F+NKIAGHPLAQNE+CLHMFLQ+E IDRNYVPGK
Sbjct:    7 ADTRRLNSKPQDLTDAYGPPSNFLEIDIFNPQTVGVGRARFTTYEVRMRTNLPIFKLKESCVRRRYSDFEWLKNELERDSKIVVPPLPGKALKRQLPFRGDEGIFEESFIEERRQGLEQFINKIAGHPLAQNERCLHMFLQEEAIDRNYVPGK 159
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Human
Match: SNX12 (sorting nexin 12 [Source:HGNC Symbol;Acc:HGNC:14976])

HSP 1 Score: 212.616 bits (540), Expect = 9.194e-69
Identity = 117/155 (75.48%), Postives = 133/155 (85.81%), Query Frame = 3 
Query:  117 AVTSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKVR 581
            A T RL  K Q + DAY PP+NFLEID+  PQT GVG+ R+TTYE    TNLP+FK K+S VRRRYSDFEWL++ELERDSKIVVP LPGKA KRQLPFRGD+GIF+E FIEERR+GLE+F+NKIAGHPLAQNE+CLHMFLQ+E IDRNYVPGKVR
Sbjct:    7 ADTRRLNSKPQDLTDAYGPPSNFLEIDIFNPQTVGVGRARFTTYE----TNLPIFKLKESCVRRRYSDFEWLKNELERDSKIVVPPLPGKALKRQLPFRGDEGIFEESFIEERRQGLEQFINKIAGHPLAQNERCLHMFLQEEAIDRNYVPGKVR 157
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Celegans
Match: snx-3 (Sorting NeXin [Source:UniProtKB/TrEMBL;Acc:Q9XW41])

HSP 1 Score: 213.001 bits (541), Expect = 3.437e-69
Identity = 110/157 (70.06%), Postives = 138/157 (87.90%), Query Frame = 3 
Query:  117 AVTSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKVRTS 587
            + T R+  K+QT+++AY+PPANFLEI++  P T GVGK RYT YE+R+ +NLPVFK K+S+VRRRYSDFEW+R+ELERDSKIVVP LPGK++KRQLPFR DDGIF+E+FIE RRK LE F+NK+AGHPLAQNE+ LH+FLQ+ TID+NYVPGK+RT+
Sbjct:    6 SATQRIPSKRQTLDEAYAPPANFLEIEVINPITHGVGKMRYTDYEIRMRSNLPVFKQKESSVRRRYSDFEWVRAELERDSKIVVPTLPGKSFKRQLPFRSDDGIFEEEFIENRRKALELFINKVAGHPLAQNERSLHIFLQEPTIDKNYVPGKIRTA 162
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Fly
Match: Snx3 (gene:FBgn0038065 transcript:FBtr0082641)

HSP 1 Score: 218.779 bits (556), Expect = 2.751e-71
Identity = 119/157 (75.80%), Postives = 135/157 (85.99%), Query Frame = 3 
Query:  120 VTSRLAPKKQTIEDAYSPPANFLEIDLSKP-QTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKVRTS 587
             T RL  KKQT++DAY+ PANFLEID+  P  T   GK RYT YEVR+ TNLPVFK K+S+VRRRYSDFEWLR+ELERDSKIVVP LPGKAWKRQ+PFRGD+GIFDE FIEERRKGLE F+NKIAGHPLAQNE+CLHMFLQ+  ID+NYVPGK+R +
Sbjct:   11 ATRRLNVKKQTLDDAYAVPANFLEIDVVNPLTTMAAGKKRYTDYEVRMRTNLPVFKVKESSVRRRYSDFEWLRNELERDSKIVVPPLPGKAWKRQMPFRGDEGIFDESFIEERRKGLEAFINKIAGHPLAQNERCLHMFLQENVIDKNYVPGKIRNT 167
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Fly
Match: Snx3 (gene:FBgn0038065 transcript:FBtr0082642)

HSP 1 Score: 218.779 bits (556), Expect = 2.751e-71
Identity = 119/157 (75.80%), Postives = 135/157 (85.99%), Query Frame = 3 
Query:  120 VTSRLAPKKQTIEDAYSPPANFLEIDLSKP-QTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKVRTS 587
             T RL  KKQT++DAY+ PANFLEID+  P  T   GK RYT YEVR+ TNLPVFK K+S+VRRRYSDFEWLR+ELERDSKIVVP LPGKAWKRQ+PFRGD+GIFDE FIEERRKGLE F+NKIAGHPLAQNE+CLHMFLQ+  ID+NYVPGK+R +
Sbjct:   11 ATRRLNVKKQTLDDAYAVPANFLEIDVVNPLTTMAAGKKRYTDYEVRMRTNLPVFKVKESSVRRRYSDFEWLRNELERDSKIVVPPLPGKAWKRQMPFRGDEGIFDESFIEERRKGLEAFINKIAGHPLAQNERCLHMFLQENVIDKNYVPGKIRNT 167
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Fly
Match: Snx1 (gene:FBgn0031534 transcript:FBtr0343238)

HSP 1 Score: 49.2914 bits (116), Expect = 2.596e-6
Identity = 44/146 (30.14%), Postives = 68/146 (46.58%), Query Frame = 3 
Query:  183 FLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDF----EWLRSELERDSKIVVP----KLPGKAWKRQLPXXXXXXXXXXXXXXXXRK-GLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKVRTS*L 593
            F+ I +S PQ  G G G Y  Y+V   TN+P FK  + +  RR+SDF    + L  +  R  +I+ P     + G    +  P + + G        E R+  LE FV++ A HP+ + +     FL+ +      +P  V TS L
Sbjct:   74 FISIVVSDPQKIGDGMGSYLAYKVTTKTNIPKFKRSEFSTLRRFSDFLGIHDLLVGKYMRLGRIIPPAPSKNIIGSTKVKISPQQSEPGTPMTQEWVEIRRAALERFVHRTAQHPVLRVDLDFMNFLESD----QELPRSVNTSAL 215
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Fly
Match: Snx1 (gene:FBgn0031534 transcript:FBtr0077517)

HSP 1 Score: 49.2914 bits (116), Expect = 2.673e-6
Identity = 44/146 (30.14%), Postives = 68/146 (46.58%), Query Frame = 3 
Query:  183 FLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDF----EWLRSELERDSKIVVP----KLPGKAWKRQLPXXXXXXXXXXXXXXXXRK-GLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKVRTS*L 593
            F+ I +S PQ  G G G Y  Y+V   TN+P FK  + +  RR+SDF    + L  +  R  +I+ P     + G    +  P + + G        E R+  LE FV++ A HP+ + +     FL+ +      +P  V TS L
Sbjct:   74 FISIVVSDPQKIGDGMGSYLAYKVTTKTNIPKFKRSEFSTLRRFSDFLGIHDLLVGKYMRLGRIIPPAPSKNIIGSTKVKISPQQSEPGTPMTQEWVEIRRAALERFVHRTAQHPVLRVDLDFMNFLESD----QELPRSVNTSAL 215
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Zebrafish
Match: snx12 (sorting nexin 12 [Source:ZFIN;Acc:ZDB-GENE-040426-787])

HSP 1 Score: 223.016 bits (567), Expect = 7.022e-73
Identity = 118/155 (76.13%), Postives = 136/155 (87.74%), Query Frame = 3 
Query:  117 AVTSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKVR 581
            A T RL  K Q + DAY PP+NFLEID+  PQT GVG+ R+TTYEVR+ TNLP+FK K+S VRRRYSDFEWL++ELERDSKIVVP LPGKA KRQLPFRGD+GIF+E FIEERR GLE+F+N+IAGHPLAQNE+CLHMFLQDE+IDRNY+PGKVR
Sbjct:    7 ADTRRLNSKPQDLTDAYGPPSNFLEIDVYDPQTIGVGRNRFTTYEVRMRTNLPIFKLKESVVRRRYSDFEWLKNELERDSKIVVPPLPGKALKRQLPFRGDEGIFEESFIEERRAGLEQFINRIAGHPLAQNERCLHMFLQDESIDRNYIPGKVR 161
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Zebrafish
Match: snx12 (sorting nexin 12 [Source:ZFIN;Acc:ZDB-GENE-040426-787])

HSP 1 Score: 221.09 bits (562), Expect = 3.628e-72
Identity = 117/154 (75.97%), Postives = 135/154 (87.66%), Query Frame = 3 
Query:  117 AVTSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKV 578
            A T RL  K Q + DAY PP+NFLEID+  PQT GVG+ R+TTYEVR+ TNLP+FK K+S VRRRYSDFEWL++ELERDSKIVVP LPGKA KRQLPFRGD+GIF+E FIEERR GLE+F+N+IAGHPLAQNE+CLHMFLQDE+IDRNY+PGKV
Sbjct:    7 ADTRRLNSKPQDLTDAYGPPSNFLEIDVYDPQTIGVGRNRFTTYEVRMRTNLPIFKLKESVVRRRYSDFEWLKNELERDSKIVVPPLPGKALKRQLPFRGDEGIFEESFIEERRAGLEQFINRIAGHPLAQNERCLHMFLQDESIDRNYIPGKV 160
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Zebrafish
Match: snx12 (sorting nexin 12 [Source:ZFIN;Acc:ZDB-GENE-040426-787])

HSP 1 Score: 221.476 bits (563), Expect = 9.187e-71
Identity = 117/154 (75.97%), Postives = 135/154 (87.66%), Query Frame = 3 
Query:  117 AVTSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKV 578
            A T RL  K Q + DAY PP+NFLEID+  PQT GVG+ R+TTYEVR+ TNLP+FK K+S VRRRYSDFEWL++ELERDSKIVVP LPGKA KRQLPFRGD+GIF+E FIEERR GLE+F+N+IAGHPLAQNE+CLHMFLQDE+IDRNY+PGKV
Sbjct:    7 ADTRRLNSKPQDLTDAYGPPSNFLEIDVYDPQTIGVGRNRFTTYEVRMRTNLPIFKLKESVVRRRYSDFEWLKNELERDSKIVVPPLPGKALKRQLPFRGDEGIFEESFIEERRAGLEQFINRIAGHPLAQNERCLHMFLQDESIDRNYIPGKV 160
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Zebrafish
Match: snx12 (sorting nexin 12 [Source:ZFIN;Acc:ZDB-GENE-040426-787])

HSP 1 Score: 221.476 bits (563), Expect = 1.098e-70
Identity = 117/154 (75.97%), Postives = 135/154 (87.66%), Query Frame = 3 
Query:  117 AVTSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKV 578
            A T RL  K Q + DAY PP+NFLEID+  PQT GVG+ R+TTYEVR+ TNLP+FK K+S VRRRYSDFEWL++ELERDSKIVVP LPGKA KRQLPFRGD+GIF+E FIEERR GLE+F+N+IAGHPLAQNE+CLHMFLQDE+IDRNY+PGKV
Sbjct:    7 ADTRRLNSKPQDLTDAYGPPSNFLEIDVYDPQTIGVGRNRFTTYEVRMRTNLPIFKLKESVVRRRYSDFEWLKNELERDSKIVVPPLPGKALKRQLPFRGDEGIFEESFIEERRAGLEQFINRIAGHPLAQNERCLHMFLQDESIDRNYIPGKV 160
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Zebrafish
Match: snx3 (sorting nexin 3 [Source:ZFIN;Acc:ZDB-GENE-030131-921])

HSP 1 Score: 211.075 bits (536), Expect = 3.192e-68
Identity = 112/162 (69.14%), Postives = 138/162 (85.19%), Query Frame = 3 
Query:  108 MSNAV--TSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKVRTS 587
            M+ A+  T RL  K Q + DAY PP+NFLEID++ P+T GVG+ R+TTYE++L TNLP+FK K+S VRRRYSDFEWLR ELER+SK+VVP LPGKA  RQLPFRGDDGIFD+ FIEERR+GLE+F+NK+AGHPLAQNE+CLHMFLQDE++D+NY P K+R +
Sbjct:    1 MAEAIADTRRLYTKPQNLNDAYGPPSNFLEIDVTNPETVGVGRNRFTTYEIKLKTNLPIFKLKESRVRRRYSDFEWLRGELERESKVVVPPLPGKALFRQLPFRGDDGIFDDSFIEERRQGLEQFLNKVAGHPLAQNERCLHMFLQDESVDKNYTPSKIRQA 162
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Xenopus
Match: snx12 (sorting nexin 12 [Source:NCBI gene;Acc:548507])

HSP 1 Score: 224.942 bits (572), Expect = 2.003e-73
Identity = 123/163 (75.46%), Postives = 139/163 (85.28%), Query Frame = 3 
Query:  108 MSNAV---TSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKVRTS 587
            MS+A    T RL  K Q + DAY PP+NFLEID+  PQT GVG+ RYT YEVR+ TNLP+FK KDS VRRRYSDFEWL++ELERDSKIVVP LPGKA KRQLPFRGD+GIF+E FIEER++GLE+F+NKIAGHPLAQNE+CLHMFLQDETIDRNYVPGKV  S
Sbjct:    1 MSDATVADTRRLNSKPQDLTDAYGPPSNFLEIDIFNPQTVGVGRNRYTVYEVRMRTNLPIFKLKDSCVRRRYSDFEWLKNELERDSKIVVPPLPGKALKRQLPFRGDEGIFEESFIEERKQGLEQFINKIAGHPLAQNERCLHMFLQDETIDRNYVPGKVFKS 163
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Xenopus
Match: snx12 (sorting nexin 12 [Source:NCBI gene;Acc:548507])

HSP 1 Score: 226.483 bits (576), Expect = 4.564e-73
Identity = 123/161 (76.40%), Postives = 139/161 (86.34%), Query Frame = 3 
Query:  108 MSNAV---TSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKVR 581
            MS+A    T RL  K Q + DAY PP+NFLEID+  PQT GVG+ RYT YEVR+ TNLP+FK KDS VRRRYSDFEWL++ELERDSKIVVP LPGKA KRQLPFRGD+GIF+E FIEER++GLE+F+NKIAGHPLAQNE+CLHMFLQDETIDRNYVPGKVR
Sbjct:   76 MSDATVADTRRLNSKPQDLTDAYGPPSNFLEIDIFNPQTVGVGRNRYTVYEVRMRTNLPIFKLKDSCVRRRYSDFEWLKNELERDSKIVVPPLPGKALKRQLPFRGDEGIFEESFIEERKQGLEQFINKIAGHPLAQNERCLHMFLQDETIDRNYVPGKVR 236
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Xenopus
Match: snx3 (sorting nexin 3 [Source:NCBI gene;Acc:394626])

HSP 1 Score: 219.55 bits (558), Expect = 2.038e-71
Identity = 114/157 (72.61%), Postives = 137/157 (87.26%), Query Frame = 3 
Query:  117 AVTSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKVRTS 587
            A T RL  K Q + DAY PP+NFLEID+S PQT GVG+GRYTTYEVRL TNLP+FK K+S VRRRYSDFEWL+SELER+SK+VVP LPGKA+ RQLPFRGD+GI+D+ FIEER++GLE+F+NK+AGHPLAQNE+CLHMFLQDE +D+NY P K+R +
Sbjct:    6 ADTRRLLSKPQNLNDAYGPPSNFLEIDVSNPQTIGVGRGRYTTYEVRLKTNLPIFKLKESCVRRRYSDFEWLKSELERESKVVVPPLPGKAFFRQLPFRGDEGIYDDSFIEERKQGLEQFINKVAGHPLAQNERCLHMFLQDEILDKNYTPSKIRHA 162
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Xenopus
Match: snx11 (sorting nexin 11 [Source:NCBI gene;Acc:100145709])

HSP 1 Score: 65.855 bits (159), Expect = 2.021e-12
Identity = 47/123 (38.21%), Postives = 72/123 (58.54%), Query Frame = 3 
Query:  183 FLEIDLSKPQTFGVGK-GRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIV-VPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDE 545
            F+ I +  P+    G    Y  Y++ L+TN   F  K S VRRRY +F+WLR  L+++S +V VP LPGK     LP        ++DFIE RR+GL++F+ +I  + +  ++  LH+FLQ +
Sbjct:   11 FITIRVQDPRLQNEGSWASYVDYKIFLHTNSKAFTAKTSCVRRRYREFDWLRKRLQKNSGLVPVPALPGK-----LP---FLVGNNDDFIERRRQGLQQFLEQIVQNMVLLSDSQLHLFLQSQ 125
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Xenopus
Match: sars2 (seryl-tRNA synthetase 2, mitochondrial [Source:Xenbase;Acc:XB-GENE-969286])

HSP 1 Score: 54.6842 bits (130), Expect = 1.536e-8
Identity = 35/104 (33.65%), Postives = 58/104 (55.77%), Query Frame = 3 
Query:  237 YTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIV-VPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDE 545
            Y  YE+ ++TN   F  K S VRRR+ +F WLR +L+ ++ +  +P+LP        P      I +   +E R +GL+EF+NK+    +  ++  LH+FLQ +
Sbjct:   24 YVDYEICVHTNSMCFTLKTSCVRRRFREFVWLRQKLQSNAVLTQLPELP--------PRIPFFKISNSQNLEHRVRGLQEFLNKVLHCSVLLSDSRLHLFLQTQ 119
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Mouse
Match: Snx12 (sorting nexin 12 [Source:MGI Symbol;Acc:MGI:1919331])

HSP 1 Score: 223.016 bits (567), Expect = 6.723e-73
Identity = 119/155 (76.77%), Postives = 136/155 (87.74%), Query Frame = 3 
Query:  117 AVTSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKVR 581
            A T RL  K Q + DAY PP+NFLEID+  PQT GVG+ R+TTYEVR+ TNLP+FK K+S VRRRYSDFEWL++ELERDSKIVVP LPGKA KRQLPFRGD+GIF+E FIEERR+GLE+F+NKIAGHPLAQNE+CLHMFLQ+E IDRNYVPGKVR
Sbjct:    7 ADTRRLNSKPQDLTDAYGPPSNFLEIDIFNPQTVGVGRARFTTYEVRMRTNLPIFKLKESCVRRRYSDFEWLKNELERDSKIVVPPLPGKALKRQLPFRGDEGIFEESFIEERRQGLEQFINKIAGHPLAQNERCLHMFLQEEAIDRNYVPGKVR 161
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Mouse
Match: Snx12 (sorting nexin 12 [Source:MGI Symbol;Acc:MGI:1919331])

HSP 1 Score: 221.09 bits (562), Expect = 3.800e-72
Identity = 118/154 (76.62%), Postives = 135/154 (87.66%), Query Frame = 3 
Query:  117 AVTSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKV 578
            A T RL  K Q + DAY PP+NFLEID+  PQT GVG+ R+TTYEVR+ TNLP+FK K+S VRRRYSDFEWL++ELERDSKIVVP LPGKA KRQLPFRGD+GIF+E FIEERR+GLE+F+NKIAGHPLAQNE+CLHMFLQ+E IDRNYVPGKV
Sbjct:    7 ADTRRLNSKPQDLTDAYGPPSNFLEIDIFNPQTVGVGRARFTTYEVRMRTNLPIFKLKESCVRRRYSDFEWLKNELERDSKIVVPPLPGKALKRQLPFRGDEGIFEESFIEERRQGLEQFINKIAGHPLAQNERCLHMFLQEEAIDRNYVPGKV 160
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Mouse
Match: Snx12 (sorting nexin 12 [Source:MGI Symbol;Acc:MGI:1919331])

HSP 1 Score: 220.705 bits (561), Expect = 6.347e-72
Identity = 118/154 (76.62%), Postives = 135/154 (87.66%), Query Frame = 3 
Query:  117 AVTSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKV 578
            A T RL  K Q + DAY PP+NFLEID+  PQT GVG+ R+TTYEVR+ TNLP+FK K+S VRRRYSDFEWL++ELERDSKIVVP LPGKA KRQLPFRGD+GIF+E FIEERR+GLE+F+NKIAGHPLAQNE+CLHMFLQ+E IDRNYVPGKV
Sbjct:    7 ADTRRLNSKPQDLTDAYGPPSNFLEIDIFNPQTVGVGRARFTTYEVRMRTNLPIFKLKESCVRRRYSDFEWLKNELERDSKIVVPPLPGKALKRQLPFRGDEGIFEESFIEERRQGLEQFINKIAGHPLAQNERCLHMFLQEEAIDRNYVPGKV 160
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Mouse
Match: Snx3 (sorting nexin 3 [Source:MGI Symbol;Acc:MGI:1860188])

HSP 1 Score: 218.779 bits (556), Expect = 2.660e-71
Identity = 115/155 (74.19%), Postives = 138/155 (89.03%), Query Frame = 3 
Query:  117 AVTSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKVR 581
            A T RL  K Q + DAY PP+NFLEID+S PQT GVG+GR+TTYE+R+ TNLP+FK K+STVRRRYSDFEWLRSELER+SK+VVP LPGKA+ RQLPFRGDDGIFD++FIEER++GLE+F+NK+AGHPLAQNE+CLHMFLQDE ID++Y P K+R
Sbjct:    6 ADTRRLITKPQNLNDAYGPPSNFLEIDVSNPQTVGVGRGRFTTYEIRVKTNLPIFKLKESTVRRRYSDFEWLRSELERESKVVVPPLPGKAFLRQLPFRGDDGIFDDNFIEERKQGLEQFINKVAGHPLAQNERCLHMFLQDEIIDKSYTPSKIR 160
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Mouse
Match: Snx3 (sorting nexin 3 [Source:MGI Symbol;Acc:MGI:1860188])

HSP 1 Score: 173.326 bits (438), Expect = 1.026e-53
Identity = 101/157 (64.33%), Postives = 120/157 (76.43%), Query Frame = 3 
Query:  117 AVTSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKVRTS 587
            A T RL  K Q + DAY PP+NFLEID                      TNLP+FK K+STVRRRYSDFEWLRSELER+SK+VVP LPGKA+ RQLPFRGDDGIFD++FIEER++GLE+F+NK+AGHPLAQNE+CLHMFLQDE ID++Y P K+R +
Sbjct:    6 ADTRRLITKPQNLNDAYGPPSNFLEID----------------------TNLPIFKLKESTVRRRYSDFEWLRSELERESKVVVPPLPGKAFLRQLPFRGDDGIFDDNFIEERKQGLEQFINKVAGHPLAQNERCLHMFLQDEIIDKSYTPSKIRHA 140
[Close]
BLAST of Sorting nexin, putative vs. UniProt/SwissProt
Match: sp|Q9UMY4|SNX12_HUMAN (Sorting nexin-12 OS=Homo sapiens OX=9606 GN=SNX12 PE=1 SV=4)

HSP 1 Score: 223.016 bits (567), Expect = 4.703e-72
Identity = 119/155 (76.77%), Postives = 136/155 (87.74%), Query Frame = 3 
Query:  117 AVTSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKVR 581
            A T RL  K Q + DAY PP+NFLEID+  PQT GVG+ R+TTYEVR+ TNLP+FK K+S VRRRYSDFEWL++ELERDSKIVVP LPGKA KRQLPFRGD+GIF+E FIEERR+GLE+F+NKIAGHPLAQNE+CLHMFLQ+E IDRNYVPGKVR
Sbjct:    7 ADTRRLNSKPQDLTDAYGPPSNFLEIDIFNPQTVGVGRARFTTYEVRMRTNLPIFKLKESCVRRRYSDFEWLKNELERDSKIVVPPLPGKALKRQLPFRGDEGIFEESFIEERRQGLEQFINKIAGHPLAQNERCLHMFLQEEAIDRNYVPGKVR 161
[Close]
BLAST of Sorting nexin, putative vs. UniProt/SwissProt
Match: sp|Q5U211|SNX3_RAT (Sorting nexin-3 OS=Rattus norvegicus OX=10116 GN=Snx3 PE=1 SV=1)

HSP 1 Score: 218.779 bits (556), Expect = 1.860e-70
Identity = 115/155 (74.19%), Postives = 138/155 (89.03%), Query Frame = 3 
Query:  117 AVTSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKVR 581
            A T RL  K Q + DAY PP+NFLEID+S PQT GVG+GR+TTYE+R+ TNLP+FK K+STVRRRYSDFEWLRSELER+SK+VVP LPGKA+ RQLPFRGDDGIFD++FIEER++GLE+F+NK+AGHPLAQNE+CLHMFLQDE ID++Y P K+R
Sbjct:    6 ADTRRLITKPQNLNDAYGPPSNFLEIDVSNPQTVGVGRGRFTTYEIRVKTNLPIFKLKESTVRRRYSDFEWLRSELERESKVVVPPLPGKAFLRQLPFRGDDGIFDDNFIEERKQGLEQFINKVAGHPLAQNERCLHMFLQDEIIDKSYTPSKIR 160
[Close]
BLAST of Sorting nexin, putative vs. UniProt/SwissProt
Match: sp|Q5R5V1|SNX3_PONAB (Sorting nexin-3 OS=Pongo abelii OX=9601 GN=SNX3 PE=2 SV=3)

HSP 1 Score: 218.779 bits (556), Expect = 1.860e-70
Identity = 115/155 (74.19%), Postives = 138/155 (89.03%), Query Frame = 3 
Query:  117 AVTSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKVR 581
            A T RL  K Q + DAY PP+NFLEID+S PQT GVG+GR+TTYE+R+ TNLP+FK K+STVRRRYSDFEWLRSELER+SK+VVP LPGKA+ RQLPFRGDDGIFD++FIEER++GLE+F+NK+AGHPLAQNE+CLHMFLQDE ID++Y P K+R
Sbjct:    6 ADTRRLITKPQNLNDAYGPPSNFLEIDVSNPQTVGVGRGRFTTYEIRVKTNLPIFKLKESTVRRRYSDFEWLRSELERESKVVVPPLPGKAFLRQLPFRGDDGIFDDNFIEERKQGLEQFINKVAGHPLAQNERCLHMFLQDEIIDKSYTPSKIR 160
[Close]
BLAST of Sorting nexin, putative vs. UniProt/SwissProt
Match: sp|O60493|SNX3_HUMAN (Sorting nexin-3 OS=Homo sapiens OX=9606 GN=SNX3 PE=1 SV=3)

HSP 1 Score: 218.779 bits (556), Expect = 1.860e-70
Identity = 115/155 (74.19%), Postives = 138/155 (89.03%), Query Frame = 3 
Query:  117 AVTSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKVR 581
            A T RL  K Q + DAY PP+NFLEID+S PQT GVG+GR+TTYE+R+ TNLP+FK K+STVRRRYSDFEWLRSELER+SK+VVP LPGKA+ RQLPFRGDDGIFD++FIEER++GLE+F+NK+AGHPLAQNE+CLHMFLQDE ID++Y P K+R
Sbjct:    6 ADTRRLITKPQNLNDAYGPPSNFLEIDVSNPQTVGVGRGRFTTYEIRVKTNLPIFKLKESTVRRRYSDFEWLRSELERESKVVVPPLPGKAFLRQLPFRGDDGIFDDNFIEERKQGLEQFINKVAGHPLAQNERCLHMFLQDEIIDKSYTPSKIR 160
[Close]
BLAST of Sorting nexin, putative vs. UniProt/SwissProt
Match: sp|Q1RMH8|SNX3_BOVIN (Sorting nexin-3 OS=Bos taurus OX=9913 GN=SNX3 PE=2 SV=3)

HSP 1 Score: 218.779 bits (556), Expect = 1.860e-70
Identity = 115/155 (74.19%), Postives = 138/155 (89.03%), Query Frame = 3 
Query:  117 AVTSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKVR 581
            A T RL  K Q + DAY PP+NFLEID+S PQT GVG+GR+TTYE+R+ TNLP+FK K+STVRRRYSDFEWLRSELER+SK+VVP LPGKA+ RQLPFRGDDGIFD++FIEER++GLE+F+NK+AGHPLAQNE+CLHMFLQDE ID++Y P K+R
Sbjct:    6 ADTRRLITKPQNLNDAYGPPSNFLEIDVSNPQTVGVGRGRFTTYEIRVKTNLPIFKLKESTVRRRYSDFEWLRSELERESKVVVPPLPGKAFLRQLPFRGDDGIFDDNFIEERKQGLEQFINKVAGHPLAQNERCLHMFLQDEIIDKSYTPSKIR 160
[Close]
BLAST of Sorting nexin, putative vs. TrEMBL
Match: A0A0B6ZLN5 (PX domain-containing protein (Fragment) OS=Arion vulgaris OX=1028688 GN=ORF67769 PE=4 SV=1)

HSP 1 Score: 236.113 bits (601), Expect = 1.114e-74
Identity = 124/162 (76.54%), Postives = 146/162 (90.12%), Query Frame = 3 
Query:  102 NIMSNAVTSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKVRTS 587
            N+ +   T+R++ KKQT+EDAYSPPANFLEID+S PQT GV K RYT YEVR+ TNLPVFK K+S VRRRYSDFEWLR+ELERDSKIVVP LPGKA KRQLPFRGDDGIF++DFI+ER+KGLE+F+NK+AGHPLAQNEKCLHMFLQ++ ID+NYVPGK+RT+
Sbjct:    3 NMTTPTATARISSKKQTLEDAYSPPANFLEIDVSDPQTHGVAKKRYTDYEVRMKTNLPVFKLKESGVRRRYSDFEWLRNELERDSKIVVPPLPGKALKRQLPFRGDDGIFEDDFIDERKKGLEQFINKVAGHPLAQNEKCLHMFLQEQVIDKNYVPGKIRTT 164
[Close]
BLAST of Sorting nexin, putative vs. TrEMBL
Match: A0A267FN58 (PX domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig000019g3 PE=4 SV=1)

HSP 1 Score: 234.958 bits (598), Expect = 3.431e-74
Identity = 124/157 (78.98%), Postives = 141/157 (89.81%), Query Frame = 3 
Query:  117 AVTSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKVRTS 587
            + T RL PKKQT+EDAYSPPANFLEID+  P+T G+ K RYT YE+RL TNLPVFK K+S+VRRRYSDFEWLR+ELERDSKIVVPKLPGKA K QLPFRG DG FD++FIEERRKGLEEF+NK+AGHPLAQNEKCLHMFLQ++TID+ YVPGKVRT+
Sbjct:   12 SATQRLQPKKQTMEDAYSPPANFLEIDVCNPETHGLNKDRYTDYEIRLRTNLPVFKLKESSVRRRYSDFEWLRAELERDSKIVVPKLPGKALKLQLPFRGGDGRFDDEFIEERRKGLEEFINKVAGHPLAQNEKCLHMFLQEQTIDKAYVPGKVRTT 168
[Close]
BLAST of Sorting nexin, putative vs. TrEMBL
Match: A0A433TSQ3 (PX domain-containing protein OS=Elysia chlorotica OX=188477 GN=EGW08_007639 PE=4 SV=1)

HSP 1 Score: 234.187 bits (596), Expect = 4.998e-74
Identity = 124/161 (77.02%), Postives = 145/161 (90.06%), Query Frame = 3 
Query:  105 IMSNAVTSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKVRTS 587
            + +   T+R++ KKQT+EDAYSPPANFLEID+S PQT GV K RYT YEVR+ TNLPVFK K+S VRRRYSDFEWLR+ELERDSKIVVP LPGKA+KRQLPFRGDDGIF+++FIE+RRKGLE+FVNK+AGHPLAQNEKCLHMFLQ+  ID+NYVPGK+RT+
Sbjct:    1 MTTPTATARISSKKQTLEDAYSPPANFLEIDVSDPQTHGVAKKRYTDYEVRMKTNLPVFKLKESGVRRRYSDFEWLRNELERDSKIVVPPLPGKAFKRQLPFRGDDGIFEDEFIEDRRKGLEQFVNKVAGHPLAQNEKCLHMFLQEPVIDKNYVPGKIRTT 161
[Close]
BLAST of Sorting nexin, putative vs. TrEMBL
Match: A0A267GGD1 (PX domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig000019g2 PE=4 SV=1)

HSP 1 Score: 235.728 bits (600), Expect = 5.055e-74
Identity = 127/170 (74.71%), Postives = 146/170 (85.88%), Query Frame = 3 
Query:  102 NIMSN--------AVTSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKVRTS 587
            ++MSN        + T RL PKKQT+EDAYSPPANFLEID+  P+T G+ K RYT YE+RL TNLPVFK K+S+VRRRYSDFEWLR+ELERDSKIVVPKLPGKA K QLPFRG DG FD++FIEERRKGLEEF+NK+AGHPLAQNEKCLHMFLQ++TID+ YVPGKVRT+
Sbjct:   26 SVMSNQQQQQQQPSATQRLQPKKQTMEDAYSPPANFLEIDVCNPETHGLNKDRYTDYEIRLRTNLPVFKLKESSVRRRYSDFEWLRAELERDSKIVVPKLPGKALKLQLPFRGGDGRFDDEFIEERRKGLEEFINKVAGHPLAQNEKCLHMFLQEQTIDKAYVPGKVRTT 195
[Close]
BLAST of Sorting nexin, putative vs. TrEMBL
Match: A0A210PRS6 (Sorting nexin-12 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT07157 PE=4 SV=1)

HSP 1 Score: 234.187 bits (596), Expect = 5.950e-74
Identity = 122/161 (75.78%), Postives = 143/161 (88.82%), Query Frame = 3 
Query:  105 IMSNAVTSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKVRTS 587
            + +   T+R+  KKQT+EDAYSPPANFLEID+  PQT GV K RYT YEVR+ TNLPVFK K+S+VRRRYSDFEWLRSELERDSKIVVP +PGKAWKRQLPFRGDDGIF+++FIE+RRKGLE+FVNK+AGHPLAQNE+CLHMFLQ+  ID+NYVPGK+R +
Sbjct:    1 MTAQPATARITTKKQTLEDAYSPPANFLEIDILDPQTHGVDKKRYTDYEVRMRTNLPVFKVKESSVRRRYSDFEWLRSELERDSKIVVPAMPGKAWKRQLPFRGDDGIFEDEFIEDRRKGLEQFVNKVAGHPLAQNERCLHMFLQEPVIDKNYVPGKIRNT 161
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Cavefish
Match: snx12 (sorting nexin 12 [Source:NCBI gene;Acc:103033647])

HSP 1 Score: 218.009 bits (554), Expect = 5.682e-71
Identity = 116/155 (74.84%), Postives = 135/155 (87.10%), Query Frame = 3 
Query:  117 AVTSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKVR 581
            A T RL  K Q + DAY PP+NFLEID+  PQT GVG+ R+TTYEVR+ TNLP+FK K+S VRRRYSDFEWL++ELERDSKIVVP LPGKA KRQLPFRGD+GIF+E FIEERR GLE+F+N+IAGHPLAQNE+CLHMFLQ+E+ DRNY+PGKVR
Sbjct:    7 ADTRRLNSKPQDLTDAYGPPSNFLEIDVYDPQTIGVGRNRFTTYEVRMRTNLPIFKLKESCVRRRYSDFEWLKNELERDSKIVVPPLPGKALKRQLPFRGDEGIFEESFIEERRVGLEQFINRIAGHPLAQNERCLHMFLQEESTDRNYIPGKVR 161
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Cavefish
Match: snx3 (sorting nexin 3 [Source:NCBI gene;Acc:103023214])

HSP 1 Score: 216.468 bits (550), Expect = 2.096e-70
Identity = 114/157 (72.61%), Postives = 136/157 (86.62%), Query Frame = 3 
Query:  117 AVTSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKVRTS 587
            A T RL  K Q + DAY PP+NFLEID+  P+T GVG+GR+TTYE+RL TNLP+FK K+S+VRRRYSDFEWLR ELER+SK+VVP LPGKA  RQLPFRGDDGIFD+ FIEERR+GLE+F+NK+AGHPLAQNE+CLHMFLQDE++D+NY P KVR +
Sbjct:    6 ADTRRLFTKPQNLSDAYGPPSNFLEIDVGSPETVGVGRGRFTTYEIRLKTNLPIFKLKESSVRRRYSDFEWLRGELERESKVVVPPLPGKALFRQLPFRGDDGIFDDSFIEERRQGLEQFLNKVAGHPLAQNERCLHMFLQDESVDKNYTPSKVRQA 162
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Cavefish
Match: snx12 (sorting nexin 12 [Source:NCBI gene;Acc:103033647])

HSP 1 Score: 215.312 bits (547), Expect = 6.089e-70
Identity = 114/154 (74.03%), Postives = 134/154 (87.01%), Query Frame = 3 
Query:  117 AVTSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKV 578
            A T RL  K Q + DAY PP+NFLEID+  PQT GVG+ R+TTYEVR+ TNLP+FK K+S VRRRYSDFEWL++ELERDSKIVVP LPGKA KRQLPFRGD+GIF+E FIEERR GLE+F+N+IAGHPLAQNE+CLHMFLQ+E+ DRNY+PGK+
Sbjct:    7 ADTRRLNSKPQDLTDAYGPPSNFLEIDVYDPQTIGVGRNRFTTYEVRMRTNLPIFKLKESCVRRRYSDFEWLKNELERDSKIVVPPLPGKALKRQLPFRGDEGIFEESFIEERRVGLEQFINRIAGHPLAQNERCLHMFLQEESTDRNYIPGKM 160
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Cavefish
Match: snx11 (sorting nexin 11 [Source:ZFIN;Acc:ZDB-GENE-041111-253])

HSP 1 Score: 65.855 bits (159), Expect = 2.421e-12
Identity = 43/123 (34.96%), Postives = 71/123 (57.72%), Query Frame = 3 
Query:  183 FLEIDLSKPQTFGVGK-GRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIV-VPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDE 545
            F+ + +  P+    G    Y  +++ L+TN   F  K S VRRRYS+F WL+ +L++++ +V VP LPGK+              + DFIE+RRKGL+ F++K+    +  ++  LH+FLQ +
Sbjct:   40 FIAVRVQDPRVVNEGSWNSYVDFKIFLHTNSKAFTAKTSCVRRRYSEFVWLKRKLQKNAGLVPVPDLPGKS---------VFAFNNTDFIEKRRKGLQNFLDKVVHMTVCLSDSQLHLFLQTQ 153
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Cavefish
Match: snx10a (sorting nexin-10A-like [Source:NCBI gene;Acc:103047354])

HSP 1 Score: 60.077 bits (144), Expect = 1.927e-10
Identity = 36/104 (34.62%), Postives = 59/104 (56.73%), Query Frame = 3 
Query:  237 YTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIV-VPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDE 545
            Y  YE+ L+TN   F+ K S VRRRYS+F WLR  L+ ++ ++ +PKLP        P      + +   + +R +GL++F+  +   PL  ++  LH+FLQ +
Sbjct:   18 YIDYEICLHTNSMCFRKKTSCVRRRYSEFVWLRQRLQDNALLIQLPKLP--------PANPFFSLNNPYQVTQRMQGLQKFLEIVLQMPLLLSDSRLHLFLQSQ 113
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Sea Lamprey
Match: snx3 (sorting nexin 3 [Source:ZFIN;Acc:ZDB-GENE-030131-921])

HSP 1 Score: 156.377 bits (394), Expect = 2.150e-48
Identity = 87/109 (79.82%), Postives = 99/109 (90.83%), Query Frame = 3 
Query:  261 NTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKVRTS 587
             TNLP+FK K++TVRRRYSDFEWL++ELERDSKIVVP LPGKA+ R LPFRGDDGIFD+ FI ERR GLE+F+NKIAGHPLAQNE+CLHMFLQDETID+ YVPGKVR +
Sbjct:    1 QTNLPIFKLKEATVRRRYSDFEWLKNELERDSKIVVPPLPGKAFTRLLPFRGDDGIFDDSFIAERRSGLEQFINKIAGHPLAQNERCLHMFLQDETIDKGYVPGKVRQT 109
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Sea Lamprey
Match: SNX10 (sorting nexin 10 [Source:HGNC Symbol;Acc:HGNC:14974])

HSP 1 Score: 60.077 bits (144), Expect = 1.667e-11
Identity = 47/133 (35.34%), Postives = 72/133 (54.14%), Query Frame = 3 
Query:  183 FLEIDLSKPQTFGVGKGR-YTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIV--VPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPG 572
            F+ I + +P        R Y +YE+ L+TN   F  K S VRRR+S+F WLR ++ +++ ++  VP+LP        P       + +D IEERRKGL+ F+NK+        +  LH+FLQ  T+ R  + G
Sbjct:    4 FIMIRVQEPFLHNSDSWRPYISYEIFLHTNSISFTRKTSRVRRRFSEFVWLRQKMMKNASMIRAVPRLP--------PKDLFFNCWCDDEIEERRKGLQTFLNKVVEIAPLLADSLLHLFLQS-TLSRQDMEG 127
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Sea Lamprey
Match: SNX10 (sorting nexin 10 [Source:HGNC Symbol;Acc:HGNC:14974])

HSP 1 Score: 52.373 bits (124), Expect = 9.162e-9
Identity = 39/124 (31.45%), Postives = 64/124 (51.61%), Query Frame = 3 
Query:  174 PANFLEIDLSKPQTFGVGKGR-YTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKI-VVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQ 539
            P  F+E+ +  PQ         +  YE+ L+TN   F  K S  RRR+ +F WLR  LE+ + +  +P LP        P       ++E+ +E RR+GL+ F+++I    +  ++  LH+FLQ
Sbjct:    3 PQEFVEVRVRDPQIQNRNSWHPHVDYEIFLHTNSISFTRKVSCTRRRFREFVWLRKCLEKSTNLEQLPDLP--------PGNLFFSCYNENDVEMRRQGLQNFLHRIVKMIVVLSDSRLHLFLQ 118
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Sea Lamprey
Match: snx30 (sorting nexin family member 30 [Source:NCBI gene;Acc:550496])

HSP 1 Score: 53.9138 bits (128), Expect = 1.453e-8
Identity = 43/132 (32.58%), Postives = 65/132 (49.24%), Query Frame = 3 
Query:  147 QTIEDAYSPPAN-FLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKI-VVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFL 536
            Q  E+  S P + F+ +D   P+        Y TY V + T    +   +  VRRRY DF+WLR++LE      ++P LP K   + +        F EDF+  R+K L++F+N++A HP        H FL
Sbjct:   14 QLGEETESEPTDLFVRVD--SPEKHVTAMETYITYRVTVRTTRSEYDGMEFVVRRRYQDFDWLRTKLEETQPTHIIPPLPEKFVMKGV-----VDRFTEDFVTTRQKALDKFLNRLANHPTLSFSSYFHSFL 138
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Sea Lamprey
Match: snx1a (sorting nexin 1a [Source:ZFIN;Acc:ZDB-GENE-060302-3])

HSP 1 Score: 51.6026 bits (122), Expect = 1.186e-7
Identity = 41/137 (29.93%), Postives = 62/137 (45.26%), Query Frame = 3 
Query:  186 LEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELER---DSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRK-GLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKVRT 584
            L I ++ P+  G G   Y  Y V   T+LP+FK K+ TV+RR+SDF  L  +L      S  +VP  P K+       +            ERR+  LE ++ + + HP    +     FL+     R+ +P  V T
Sbjct:  169 LRITITNPEKVGDGMNAYMAYNVTTTTSLPMFKRKEFTVKRRFSDFLGLYEKLTEKFSHSGFIVPPAPEKSVLGMTKVKVGKDDPSSVEFVERRRAALERYLQRTSKHPTLMQDPDFRDFLE-----RDELPRAVNT 300
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Yeast
Match: SNX3 (Sorting nexin for late-Golgi enzymes; required to maintain late-Golgi resident enzymes in their proper location by recycling molecules from the prevacuolar compartment; contains a PX domain and sequence similarity to human Snx3p [Source:SGD;Acc:S000005884])

HSP 1 Score: 78.5666 bits (192), Expect = 3.141e-18
Identity = 57/140 (40.71%), Postives = 79/140 (56.43%), Query Frame = 3 
Query:  159 DAYSPPANFLEIDLSKPQTF---GV-GKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERD------SKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQN-EKCLHMFLQDE 545
            + Y+ P NFLEI++  P+T    G+  KG +T YE+   TNLP F  + S VRRRYSDFE+ R  L ++       K++VP LPGK              F  + IEERR+GL  ++  +AGHPL Q+  K L  F++ E
Sbjct:   27 EIYAEPENFLEIEVHNPKTHIPNGMDSKGMFTDYEIICRTNLPSFHKRVSKVRRRYSDFEFFRKCLIKEISMLNHPKVMVPHLPGKIL--------LSNRFSNEVIEERRQGLNTWMQSVAGHPLLQSGSKVLVRFIEAE 158
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Nematostella
Match: EDO38324 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SD93])

HSP 1 Score: 218.009 bits (554), Expect = 1.927e-71
Identity = 116/155 (74.84%), Postives = 137/155 (88.39%), Query Frame = 3 
Query:  123 TSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKVRTS 587
            T RL  KKQ ++DAY+ PANFLEID+  P+T GVGK RYT YE+R+ TNLPVFK K+S+VRRRYSDFEWLRSELERDSKIVVP LPGKA KR LPFRGDDGIF+++FIE+RR+GLE F+N++AGHPLAQNEKCLHMFLQ+  ID+NYVPGKVR++
Sbjct:   14 TKRLEFKKQNLDDAYAAPANFLEIDVVNPETHGVGKKRYTDYELRMRTNLPVFKQKESSVRRRYSDFEWLRSELERDSKIVVPALPGKALKRMLPFRGDDGIFEDEFIEDRRQGLEAFINRVAGHPLAQNEKCLHMFLQEPMIDKNYVPGKVRST 168
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Nematostella
Match: EDO37393 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFV3])

HSP 1 Score: 58.151 bits (139), Expect = 1.036e-9
Identity = 46/123 (37.40%), Postives = 68/123 (55.28%), Query Frame = 3 
Query:  180 NFLEIDLSKPQT-FGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVV--PKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQ 539
             ++++++  P+T    GK  YT YEV + TN P F    S  RRRYS+F WLRS L     I++  P LP    ++QL      G F E F+ ER+ GL++F+N++    +   E  L +FLQ
Sbjct:   13 TYVDVEVKFPRTHVHEGKALYTDYEVEVKTNHPCFPLFHSNTRRRYSEFAWLRSRLGLHDFILIRTPSLP----RKQL-----IGRFKEGFLCERQAGLQKFMNRVVETSIYLQEPVLQLFLQ 126
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Nematostella
Match: EDO34587 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNW9])

HSP 1 Score: 54.299 bits (129), Expect = 2.842e-9
Identity = 45/130 (34.62%), Postives = 73/130 (56.15%), Query Frame = 3 
Query:  183 FLEIDLSKPQTFGVGKG-RYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQD----ETIDR 557
            FL + +  P+T   G+  ++T YE+ + TN   F    S VRRR+S+FEWLR+ LE++  I +   P       LP +   G F++ FI+ER++ L++F+ ++       +E  LH+FLQ      TI+R
Sbjct:    9 FLSVVVRNPRTHLRGRWPQFTDYEILIWTNSTCFVSSKSCVRRRFSEFEWLRNILEQNGSISLQPPP-------LPHKRLLGRFNQSFIKERQQELQDFLVRVLAVTSYLSEAALHLFLQTNLSINTIER 131
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Nematostella
Match: EDO48737 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RIL9])

HSP 1 Score: 53.9138 bits (128), Expect = 1.854e-8
Identity = 43/140 (30.71%), Postives = 73/140 (52.14%), Query Frame = 3 
Query:  192 IDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERD------SKIVVPKLPGK-AWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDE-TIDR--NYVPGKVR 581
            +++++PQ       ++  YE+ + TN   F  K S +RRRYSDF WLR +L  +      S+ VVP LP K  + R  P           F+  R+ GL++F++K+       +   LH+FLQ + ++D+   Y+ G+ +
Sbjct:   48 VEVNRPQIHICKGSKFVDYEIYIQTNNMAFAKKLSNIRRRYSDFIWLRKQLTTNEVNGFGSERVVPCLPPKRLFGRFEP----------KFVFSRKHGLQDFLDKVLSIRDFLSYSGLHLFLQSKLSVDQIEAYLDGRYK 177
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Nematostella
Match: EDO32102 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SW17])

HSP 1 Score: 47.7506 bits (112), Expect = 2.744e-6
Identity = 34/130 (26.15%), Postives = 63/130 (48.46%), Query Frame = 3 
Query:  186 LEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKI-----VVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKG-LEEFVNKIAGHPLAQNEKCLHMFLQDETIDR 557
            +EI ++ P+  G G   + +Y V   T++P F   ++TV+RR+SDF  L   +  ++K      +VP  P K+       +      +      +R+  LE F+N++A HP  + +     FL+ + + R
Sbjct:   14 MEIKVTDPEKVGDGMNAFMSYRVITKTSMPEFNSPETTVKRRFSDFLGLHERI--NAKYLHLGRIVPPAPEKSVIGMSKVKFSKEDSNSTDFIGKRRAVLERFLNRVAAHPELRKDPDFRQFLEADELPR 141
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Medaka
Match: snx12 (sorting nexin 12 [Source:NCBI gene;Acc:101173568])

HSP 1 Score: 219.935 bits (559), Expect = 8.414e-72
Identity = 117/155 (75.48%), Postives = 134/155 (86.45%), Query Frame = 3 
Query:  117 AVTSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKVR 581
            A T RL  K Q + DAY PP+NFLEID+  PQ  GVG+ RYTTYEVR+ TNLP+FK KDS VRRRYSDFEWL++ELERDSKIVVP LPGKA KRQLPFRGD+G+F+E FIEERR GLE+F+N+IAGHPLAQNE+CLHMFLQ+E IDRNY+PGKVR
Sbjct:    7 ADTRRLNSKPQDLTDAYGPPSNFLEIDVYDPQIVGVGRNRYTTYEVRMRTNLPIFKLKDSCVRRRYSDFEWLKNELERDSKIVVPPLPGKALKRQLPFRGDEGLFEESFIEERRVGLEQFINRIAGHPLAQNERCLHMFLQEEAIDRNYIPGKVR 161
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Medaka
Match: snx3 (sorting nexin 3 [Source:NCBI gene;Acc:101156214])

HSP 1 Score: 218.779 bits (556), Expect = 2.666e-71
Identity = 115/162 (70.99%), Postives = 142/162 (87.65%), Query Frame = 3 
Query:  108 MSNAV--TSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDRNYVPGKVRTS 587
            M++A+  T RL  K Q + DAY PP+NFLEID+S P+T GVG+GR+TTYE+RL TNLP+FK K+S+VRRRYSDFEWLR+ELER+SK+VVP LPGKA  RQLPFRGDDGIFD+ FIEERR+GLE+F+NK+AGHPLAQNE+CLHMFLQDE++D+NY P K+R +
Sbjct:    1 MADAIADTRRLFTKPQNLNDAYGPPSNFLEIDVSNPETVGVGRGRFTTYEIRLKTNLPIFKLKESSVRRRYSDFEWLRAELERESKVVVPPLPGKALFRQLPFRGDDGIFDDSFIEERRQGLEQFLNKVAGHPLAQNERCLHMFLQDESVDKNYTPSKIRQA 162
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Medaka
Match: ENSORLT00000030188.1 (sorting nexin 11 [Source:NCBI gene;Acc:101163529])

HSP 1 Score: 65.4698 bits (158), Expect = 1.842e-11
Identity = 44/121 (36.36%), Postives = 72/121 (59.50%), Query Frame = 3 
Query:  183 FLEIDLSKPQTFGVGK-GRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIV-VPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQ 539
            F+ + +  P+    G    Y  Y++ L+TN   F  K S VRRRYS+F WL+ +L+++S +V VP LPGK++             +EDF+E+RR+GL+ F++K+    +  ++  LH+FLQ
Sbjct:   10 FVAVRVQDPRIQNEGNWNSYVDYKIFLHTNSKAFTAKTSCVRRRYSEFVWLKKKLQKNSGLVPVPDLPGKSF---------FSFSNEDFLEKRRRGLQAFLDKVVHMTVCLSDSQLHLFLQ 121
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Medaka
Match: ENSORLT00000038263.1 (sorting nexin 11 [Source:NCBI gene;Acc:101163529])

HSP 1 Score: 65.4698 bits (158), Expect = 1.967e-11
Identity = 44/121 (36.36%), Postives = 72/121 (59.50%), Query Frame = 3 
Query:  183 FLEIDLSKPQTFGVGK-GRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIV-VPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQ 539
            F+ + +  P+    G    Y  Y++ L+TN   F  K S VRRRYS+F WL+ +L+++S +V VP LPGK++             +EDF+E+RR+GL+ F++K+    +  ++  LH+FLQ
Sbjct:    4 FVAVRVQDPRIQNEGNWNSYVDYKIFLHTNSKAFTAKTSCVRRRYSEFVWLKKKLQKNSGLVPVPDLPGKSF---------FSFSNEDFLEKRRRGLQAFLDKVVHMTVCLSDSQLHLFLQ 115
[Close]
BLAST of Sorting nexin, putative vs. Ensembl Medaka
Match: ENSORLT00000038972.1 (sorting nexin 11 [Source:NCBI gene;Acc:101163529])

HSP 1 Score: 65.0846 bits (157), Expect = 2.090e-11
Identity = 44/121 (36.36%), Postives = 72/121 (59.50%), Query Frame = 3 
Query:  183 FLEIDLSKPQTFGVGK-GRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIV-VPKLPGKAWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQ 539
            F+ + +  P+    G    Y  Y++ L+TN   F  K S VRRRYS+F WL+ +L+++S +V VP LPGK++             +EDF+E+RR+GL+ F++K+    +  ++  LH+FLQ
Sbjct:   10 FVAVRVQDPRIQNEGNWNSYVDYKIFLHTNSKAFTAKTSCVRRRYSEFVWLKKKLQKNSGLVPVPDLPGKSF---------FSFSNEDFLEKRRRGLQAFLDKVVHMTVCLSDSQLHLFLQ 121
[Close]
BLAST of Sorting nexin, putative vs. Planmine SMEST
Match: SMESG000016883.1 (SMESG000016883.1)

HSP 1 Score: 140.969 bits (354), Expect = 4.724e-42
Identity = 65/86 (75.58%), Postives = 75/86 (87.21%), Query Frame = 3 
Query:  108 MSNAVTSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIV 365
            M+++VTSRL  K+QTIEDAYSPPANFLEID+   QT G+GK RYT YEVRL+TNLPVFK K S+VRRRYSDFEWLR ELERDSK++
Sbjct:    1 MASSVTSRLDSKRQTIEDAYSPPANFLEIDVCNSQTHGIGKARYTDYEVRLSTNLPVFKLKKSSVRRRYSDFEWLRLELERDSKVI 86
[Close]
BLAST of Sorting nexin, putative vs. Planmine SMEST
Match: SMESG000016192.1 (SMESG000016192.1)

HSP 1 Score: 59.6918 bits (143), Expect = 8.210e-10
Identity = 42/130 (32.31%), Postives = 66/130 (50.77%), Query Frame = 3 
Query:  168 SPPANFLEIDLSKPQTFGVGKGRYTTYEVRLNTNLPVFKYKDSTVRRRYSDFEWLRSELERD---SKIVVPKLPGK-AWKRQLPXXXXXXXXXXXXXXXXRKGLEEFVNKIAGHPLAQNEKCLHMFLQDE 545
            S    F+EI +S P+  G G   Y  Y++   TN P F +++ TVRRR+SDF  L   L+     +  ++P  P K A+         +   + +F+E RR  LE ++ +IA HPL   +     FL+D+
Sbjct:   57 SKTGKFIEISVSYPEKLGSGMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCIIPPAPEKNAFGNTKLKLSKEDQTNSEFLERRRAALERYLQRIARHPLLVIDADFREFLEDD 186
The following BLAST results are available for this feature:
BLAST of Sorting nexin, putative vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SNX129.793e-7376.77sorting nexin 12 [Source:HGNC Symbol;Acc:HGNC:1497... [more]
SNX129.793e-7376.77sorting nexin 12 [Source:HGNC Symbol;Acc:HGNC:1497... [more]
SNX33.874e-7174.19sorting nexin 3 [Source:HGNC Symbol;Acc:HGNC:11174... [more]
SNX126.484e-7176.47sorting nexin 12 [Source:HGNC Symbol;Acc:HGNC:1497... [more]
SNX129.194e-6975.48sorting nexin 12 [Source:HGNC Symbol;Acc:HGNC:1497... [more]
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BLAST of Sorting nexin, putative vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
snx-33.437e-6970.06Sorting NeXin [Source:UniProtKB/TrEMBL;Acc:Q9XW41... [more]
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BLAST of Sorting nexin, putative vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Snx32.751e-7175.80gene:FBgn0038065 transcript:FBtr0082641[more]
Snx32.751e-7175.80gene:FBgn0038065 transcript:FBtr0082642[more]
Snx12.596e-630.14gene:FBgn0031534 transcript:FBtr0343238[more]
Snx12.673e-630.14gene:FBgn0031534 transcript:FBtr0077517[more]
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BLAST of Sorting nexin, putative vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
snx127.022e-7376.13sorting nexin 12 [Source:ZFIN;Acc:ZDB-GENE-040426-... [more]
snx123.628e-7275.97sorting nexin 12 [Source:ZFIN;Acc:ZDB-GENE-040426-... [more]
snx129.187e-7175.97sorting nexin 12 [Source:ZFIN;Acc:ZDB-GENE-040426-... [more]
snx121.098e-7075.97sorting nexin 12 [Source:ZFIN;Acc:ZDB-GENE-040426-... [more]
snx33.192e-6869.14sorting nexin 3 [Source:ZFIN;Acc:ZDB-GENE-030131-9... [more]
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BLAST of Sorting nexin, putative vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
snx122.003e-7375.46sorting nexin 12 [Source:NCBI gene;Acc:548507][more]
snx124.564e-7376.40sorting nexin 12 [Source:NCBI gene;Acc:548507][more]
snx32.038e-7172.61sorting nexin 3 [Source:NCBI gene;Acc:394626][more]
snx112.021e-1238.21sorting nexin 11 [Source:NCBI gene;Acc:100145709][more]
sars21.536e-833.65seryl-tRNA synthetase 2, mitochondrial [Source:Xen... [more]
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BLAST of Sorting nexin, putative vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Snx126.723e-7376.77sorting nexin 12 [Source:MGI Symbol;Acc:MGI:191933... [more]
Snx123.800e-7276.62sorting nexin 12 [Source:MGI Symbol;Acc:MGI:191933... [more]
Snx126.347e-7276.62sorting nexin 12 [Source:MGI Symbol;Acc:MGI:191933... [more]
Snx32.660e-7174.19sorting nexin 3 [Source:MGI Symbol;Acc:MGI:1860188... [more]
Snx31.026e-5364.33sorting nexin 3 [Source:MGI Symbol;Acc:MGI:1860188... [more]
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BLAST of Sorting nexin, putative vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9UMY4|SNX12_HUMAN4.703e-7276.77Sorting nexin-12 OS=Homo sapiens OX=9606 GN=SNX12 ... [more]
sp|Q5U211|SNX3_RAT1.860e-7074.19Sorting nexin-3 OS=Rattus norvegicus OX=10116 GN=S... [more]
sp|Q5R5V1|SNX3_PONAB1.860e-7074.19Sorting nexin-3 OS=Pongo abelii OX=9601 GN=SNX3 PE... [more]
sp|O60493|SNX3_HUMAN1.860e-7074.19Sorting nexin-3 OS=Homo sapiens OX=9606 GN=SNX3 PE... [more]
sp|Q1RMH8|SNX3_BOVIN1.860e-7074.19Sorting nexin-3 OS=Bos taurus OX=9913 GN=SNX3 PE=2... [more]
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BLAST of Sorting nexin, putative vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0B6ZLN51.114e-7476.54PX domain-containing protein (Fragment) OS=Arion v... [more]
A0A267FN583.431e-7478.98PX domain-containing protein OS=Macrostomum lignan... [more]
A0A433TSQ34.998e-7477.02PX domain-containing protein OS=Elysia chlorotica ... [more]
A0A267GGD15.055e-7474.71PX domain-containing protein (Fragment) OS=Macrost... [more]
A0A210PRS65.950e-7475.78Sorting nexin-12 OS=Mizuhopecten yessoensis OX=657... [more]
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BLAST of Sorting nexin, putative vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
snx125.682e-7174.84sorting nexin 12 [Source:NCBI gene;Acc:103033647][more]
snx32.096e-7072.61sorting nexin 3 [Source:NCBI gene;Acc:103023214][more]
snx126.089e-7074.03sorting nexin 12 [Source:NCBI gene;Acc:103033647][more]
snx112.421e-1234.96sorting nexin 11 [Source:ZFIN;Acc:ZDB-GENE-041111-... [more]
snx10a1.927e-1034.62sorting nexin-10A-like [Source:NCBI gene;Acc:10304... [more]
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BLAST of Sorting nexin, putative vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
snx32.150e-4879.82sorting nexin 3 [Source:ZFIN;Acc:ZDB-GENE-030131-9... [more]
SNX101.667e-1135.34sorting nexin 10 [Source:HGNC Symbol;Acc:HGNC:1497... [more]
SNX109.162e-931.45sorting nexin 10 [Source:HGNC Symbol;Acc:HGNC:1497... [more]
snx301.453e-832.58sorting nexin family member 30 [Source:NCBI gene;A... [more]
snx1a1.186e-729.93sorting nexin 1a [Source:ZFIN;Acc:ZDB-GENE-060302-... [more]
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BLAST of Sorting nexin, putative vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
SNX33.141e-1840.71Sorting nexin for late-Golgi enzymes; required to ... [more]
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BLAST of Sorting nexin, putative vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO383241.927e-7174.84Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO373931.036e-937.40Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO345872.842e-934.62Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO487371.854e-830.71Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO321022.744e-626.15Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Sorting nexin, putative vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
snx128.414e-7275.48sorting nexin 12 [Source:NCBI gene;Acc:101173568][more]
snx32.666e-7170.99sorting nexin 3 [Source:NCBI gene;Acc:101156214][more]
ENSORLT00000030188.11.842e-1136.36sorting nexin 11 [Source:NCBI gene;Acc:101163529][more]
ENSORLT00000038263.11.967e-1136.36sorting nexin 11 [Source:NCBI gene;Acc:101163529][more]
ENSORLT00000038972.12.090e-1136.36sorting nexin 11 [Source:NCBI gene;Acc:101163529][more]
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BLAST of Sorting nexin, putative vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000016883.14.724e-4275.58SMESG000016883.1[more]
SMESG000016192.18.210e-1032.31SMESG000016192.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30020813 ID=SMED30020813|Name=Sorting nexin, putative|organism=Schmidtea mediterranea sexual|type=transcript|length=944bp
GGGTTGTTTTCGTTTCATGCAAAGTTTATATTAATTTAAATTAGCACATT
AACAGAATTTCTGAGACATCATTTTATTAATCAAGTTAAAATATTTGATG
AAACATTATGTCTAATGCTGTAACAAGCCGCTTGGCCCCAAAGAAGCAAA
CAATTGAAGATGCATATTCGCCTCCTGCAAATTTTTTAGAAATTGATCTT
AGCAAACCACAAACATTTGGTGTTGGAAAAGGACGTTATACAACATATGA
AGTTCGATTAAATACTAATTTGCCAGTTTTTAAATACAAAGATTCAACAG
TTCGTCGACGGTATAGTGATTTTGAGTGGCTAAGATCTGAGTTGGAAAGA
GATAGCAAAATTGTTGTGCCCAAACTTCCTGGTAAAGCTTGGAAACGTCA
ATTGCCATTTCGGGGTGATGATGGAATTTTTGATGAGGATTTTATTGAAG
AAAGGCGGAAAGGCTTAGAAGAATTTGTTAACAAAATAGCTGGACATCCT
CTAGCTCAAAATGAAAAATGTTTACACATGTTTCTGCAAGATGAAACGAT
CGATCGCAATTATGTCCCAGGAAAGGTCCGAACTTCATGACTATGAAAAA
TGACTTATCGAAATTTAATTGTATTTATTTCTTGTATGAGCTGATCAATT
CTGTTTTTTATGTTGCGCGTGTGCTTGTCCATGCCAACCAGTGTTCTAAG
TAACTATCACCATTATTCCAATTGAGATGTTAAAATTATCTTAATTGTTG
TAAATTTGTTCGTGGTAACCATTTATTAATATCAACTGTTTAGTGGAAAT
TGTATTGAAATCGAATTATTTTAATCAAATGTCATTTTTCTTAGAATTCC
AACTTGGGTCGGTTCAATACATAGCATTTTATAATTAGTTGTTCGTCTTG
GATGAGTAAAAATGCGTGCAATCAATAAATAATATCACATTATA
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protein sequence of SMED30020813-orf-1

>SMED30020813-orf-1 ID=SMED30020813-orf-1|Name=SMED30020813-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=161bp
MSNAVTSRLAPKKQTIEDAYSPPANFLEIDLSKPQTFGVGKGRYTTYEVR
LNTNLPVFKYKDSTVRRRYSDFEWLRSELERDSKIVVPKLPGKAWKRQLP
FRGDDGIFDEDFIEERRKGLEEFVNKIAGHPLAQNEKCLHMFLQDETIDR
NYVPGKVRTS*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
Vocabulary: INTERPRO
TermDefinition
IPR036871PX_dom_sf
IPR001683Phox
Vocabulary: molecular function
TermDefinition
GO:0035091phosphatidylinositol binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001683Phox homologous domainSMARTSM00312PX_2coord: 24..146
e-value: 1.1E-30
score: 118.0
IPR001683Phox homologous domainPFAMPF00787PXcoord: 25..145
e-value: 7.3E-28
score: 96.8
IPR001683Phox homologous domainPROSITEPS50195PXcoord: 25..149
score: 18.563
IPR036871PX domain superfamilyGENE3DG3DSA:3.30.1520.10coord: 19..160
e-value: 9.8E-43
score: 147.2
IPR036871PX domain superfamilySUPERFAMILYSSF64268PX domaincoord: 22..146
NoneNo IPR availablePANTHERPTHR45963FAMILY NOT NAMEDcoord: 4..159
NoneNo IPR availablePANTHERPTHR45963:SF3SORTING NEXIN-12coord: 4..159
NoneNo IPR availableCDDcd06894PX_SNX3_likecoord: 26..148
e-value: 9.53854E-83
score: 237.742