slc22a-6
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30020778 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 4
Homology
BLAST of slc22a-6 vs. Ensembl Human
Match: SLC22A6 (solute carrier family 22 member 6 [Source:HGNC Symbol;Acc:HGNC:10970]) HSP 1 Score: 121.709 bits (304), Expect = 2.411e-28 Identity = 108/472 (22.88%), Postives = 212/472 (44.92%), Query Frame = 1
Query: 379 LPKNQTNQVFTEHRNQFKAINNETGFLIIDSSRCRLTNISSICSEIFV-KKYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQIDKYIEIFE---EERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIIL---KYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEKNFVE 1773
LP+++ Q + + + + G ++ + T + C++ ++ STI +++ L C + AL A S++M+G+ LG++ G +D GR L+Y +V T AA +P + ++ RL +G A++ ++ + +E + I R G Y +G LL +A+ + LQL + I+ +F+ ES RW ++ + + + +A+ N K E +E+ ++ L + S E+ + + L L ++F+ SF+YY ++ I+ +I L ++ + + LGR ++ AL +A I + I ++I+ T L ++ +F +++Y GE +PT+IR T + +GS ARV +++ + E+ P++ I + + S T LLPET +P D + E +
Sbjct: 67 LPRDRQGQ----PESCLRFTSPQWGLPFLNGTEANGTGATEPCTDGWIYDNSTFPSTIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKR--EEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMA------ALLLAGICILLNGVIPQDQSIVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSMTAELYPSMPLFIYGAVPVAASAVT-VLLPETLGQPLPDTVQDLESRWAP 525
BLAST of slc22a-6 vs. Ensembl Human
Match: SLC22A6 (solute carrier family 22 member 6 [Source:HGNC Symbol;Acc:HGNC:10970]) HSP 1 Score: 120.939 bits (302), Expect = 3.075e-28 Identity = 108/467 (23.13%), Postives = 211/467 (45.18%), Query Frame = 1
Query: 379 LPKNQTNQVFTEHRNQFKAINNETGFLIIDSSRCRLTNISSICSEIFV-KKYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQIDKYIEIFE---EERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIIL---KYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAE 1758
LP+++ Q + + + + G ++ + T + C++ ++ STI +++ L C + AL A S++M+G+ LG++ G +D GR L+Y +V T AA +P + ++ RL +G A++ ++ + +E + I R G Y +G LL +A+ + LQL + I+ +F+ ES RW ++ + + + +A+ N K E +E+ ++ L + S E+ + + L L ++F+ SF+YY ++ I+ +I L ++ + + LGR ++ AL +A I + I ++I+ T L ++ +F +++Y GE +PT+IR T + +GS ARV +++ + E+ P++ I + + S T LLPET +P D + E
Sbjct: 67 LPRDRQGQ----PESCLRFTSPQWGLPFLNGTEANGTGATEPCTDGWIYDNSTFPSTIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKR--EEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMA------ALLLAGICILLNGVIPQDQSIVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSMTAELYPSMPLFIYGAVPVAASAVT-VLLPETLGQPLPDTVQDLE 520
BLAST of slc22a-6 vs. Ensembl Human
Match: SLC22A8 (solute carrier family 22 member 8 [Source:HGNC Symbol;Acc:HGNC:10972]) HSP 1 Score: 114.775 bits (286), Expect = 3.475e-26 Identity = 124/535 (23.18%), Postives = 233/535 (43.55%), Query Frame = 1
Query: 241 KIYQLVGGNSYFQYFILMFIFISQFNTAINILMPIFINNYQDVYCVLPKNQTNQVFTEHRNQFKAINNETGFLIIDSSRCRLTNISSICSEIFVKKYPMTST---IRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGR--IIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQID-KYIEIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPII-GMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEKNFVEWRQPWR-----KSSKKI 1809
+I VG +FQ+ + + + N A + L+ IF +C P N + + E + L N + E + + ST I +++ L C + L A S+FM GI +G + G SD FGR I+ C SY +++ + AA SP + ++ + R GF +S +S + +E V R Y G +L LA+ I LQL +V + ++ ES RWL+ + K KA K++ +A FN K ++ + +++ ++ + + + ++F+ ++ L +F+ F+YY+ +G + ++ +I + ++ I + LGR T + + A + L ++ + TVL + ++F +++Y E +PTVIR T + + + RV M++ ++ E+ P + II G+T + GS F LPET +P + + E + ++P + K+S++I
Sbjct: 5 EILDRVGSMGHFQFLHVAILGLPILNMANHNLLQIFTAATPVHHCRPPHNASTGPWVLPMGPNG--KPERCLRFVHPPNASLPNDTQRAMEPCLDGWVYNSTKDSIVTEWDLVCNSNKLKEMAQSIFMAGILIGGLVLGDLSDRFGRRPILTC--SYLLLAASGSGAAFSPTFPIYMVFRFLCGFGISGITLSTVILNVEWVPTRMRAIMSTALGYCYTFGQFILPGLAYAIPQWRWLQLTVSIPFFVFFLSSWWTPESIRWLVLSGKSSKALKILRRVAVFNGKKEEGERLSLEELKLNLQKEISLAKAKYTASDLFRIPMLRRMTFCLSLAWFATGFAYYSLAMGVEEFGVNLYILQIIFGGVDVPAKFITILSLSYLGRHT---TQAAALLLAGGAILALTFVPLDLQTVRTVLAVFGKGCLSSSFSCLFLYTSELYPTVIRQTGMGVSNLWTRVGSMVSPLVKITGEVQPFIPNIIYGITALLGGSAALF--LPETLNQPLPETIEDLENWSLRAKKPKQEPEVEKASQRI 530
BLAST of slc22a-6 vs. Ensembl Human
Match: SLC22A8 (solute carrier family 22 member 8 [Source:HGNC Symbol;Acc:HGNC:10972]) HSP 1 Score: 114.775 bits (286), Expect = 3.475e-26 Identity = 124/535 (23.18%), Postives = 233/535 (43.55%), Query Frame = 1
Query: 241 KIYQLVGGNSYFQYFILMFIFISQFNTAINILMPIFINNYQDVYCVLPKNQTNQVFTEHRNQFKAINNETGFLIIDSSRCRLTNISSICSEIFVKKYPMTST---IRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGR--IIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQID-KYIEIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPII-GMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEKNFVEWRQPWR-----KSSKKI 1809
+I VG +FQ+ + + + N A + L+ IF +C P N + + E + L N + E + + ST I +++ L C + L A S+FM GI +G + G SD FGR I+ C SY +++ + AA SP + ++ + R GF +S +S + +E V R Y G +L LA+ I LQL +V + ++ ES RWL+ + K KA K++ +A FN K ++ + +++ ++ + + + ++F+ ++ L +F+ F+YY+ +G + ++ +I + ++ I + LGR T + + A + L ++ + TVL + ++F +++Y E +PTVIR T + + + RV M++ ++ E+ P + II G+T + GS F LPET +P + + E + ++P + K+S++I
Sbjct: 5 EILDRVGSMGHFQFLHVAILGLPILNMANHNLLQIFTAATPVHHCRPPHNASTGPWVLPMGPNG--KPERCLRFVHPPNASLPNDTQRAMEPCLDGWVYNSTKDSIVTEWDLVCNSNKLKEMAQSIFMAGILIGGLVLGDLSDRFGRRPILTC--SYLLLAASGSGAAFSPTFPIYMVFRFLCGFGISGITLSTVILNVEWVPTRMRAIMSTALGYCYTFGQFILPGLAYAIPQWRWLQLTVSIPFFVFFLSSWWTPESIRWLVLSGKSSKALKILRRVAVFNGKKEEGERLSLEELKLNLQKEISLAKAKYTASDLFRIPMLRRMTFCLSLAWFATGFAYYSLAMGVEEFGVNLYILQIIFGGVDVPAKFITILSLSYLGRHT---TQAAALLLAGGAILALTFVPLDLQTVRTVLAVFGKGCLSSSFSCLFLYTSELYPTVIRQTGMGVSNLWTRVGSMVSPLVKITGEVQPFIPNIIYGITALLGGSAALF--LPETLNQPLPETIEDLENWSLRAKKPKQEPEVEKASQRI 530
BLAST of slc22a-6 vs. Ensembl Human
Match: SLC22A7 (solute carrier family 22 member 7 [Source:HGNC Symbol;Acc:HGNC:10971]) HSP 1 Score: 114.005 bits (284), Expect = 6.075e-26 Identity = 118/482 (24.48%), Postives = 212/482 (43.98%), Query Frame = 1
Query: 238 EKIYQLVGGNSYFQYFILMFIFISQFNTAINILMPIFIN----------------NYQDVY--CVLPKNQTNQVFTEHRNQFKAINNETGFLIIDSSRCRLTNISSI--CSEIFVKKY-PMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQIDKYI--EIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIAS 1614
E++ + VGG FQ + + + + ++ L+PIF+ ++QDV+ LP+ + + R + T SR L + + CS+ + + +STI +++ L CE L+ A++ F G+ +G+V G SD FGR ++Y V +A S Y + A+ R TG A++ + + LE +++ RT G S + G +LL L+ + IRD L LA ++ ++ ES RWLL K+A + ++H A+ N + V E+ + ++ ER V R S ++F+ + L ++F +FSYY L S + ++ L+ L S+ + + GR LG TAL + +L + +TVL ++ + S F +++ E +PTV+R T + + + R+ G +A
Sbjct: 4 EELLEQVGGFGPFQLRNVALLALPRVLLPLHFLLPIFLAAVPAHRCALPGAPANFSHQDVWLEAHLPREPDGTLSSCLRFAYPQALPNTTLGEERQSRGELEDEPATVPCSQGWEYDHSEFSSTIATEWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYVSTLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLELEWLDVEHRTVAGVLSSTFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSFSQEAVSKVAAGER---VVRRPSYLDLFRTPRLRHISLCCVVVWFGVNFSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLG-TALAFGTRLL--VSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSLAP 479
BLAST of slc22a-6 vs. Ensembl Celegans
Match: K05F1.6 (pep chromosome:WBcel235:II:5782942:5787658:1 gene:WBGene00019408.1 transcript:K05F1.6c.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:K05F1.6) HSP 1 Score: 99.3673 bits (246), Expect = 2.534e-21 Identity = 136/574 (23.69%), Postives = 246/574 (42.86%), Query Frame = 1
Query: 238 EKIYQLVGGNSYFQYFILMFIFISQFNTAINILMPIFINNYQDVYCVLPK-NQTNQV-FTEHR------NQFKAIN------NETGFLIIDS-----------SRCRLTNISSICSEIFVKKYP-------------MTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGR---IIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAK-----FNRKSVTE-NQIDKYIEI--FEEERL-RSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDE---IFTA--ALISALGSLVSRSIYMFLC---KRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTM----AMFGSLCTFFLLPETFKRPSSDFLSQAEKNFVE 1773
E I ++GG ++Q +I + I + Q A+ L +++ + C++P N TN + H + K I+ N G DS + R + + SE + P M TI + F L C+ A + +G LG V GG+ SD GR IIG G+ M+ VF + +Y + L RL + + ++ + +EI R G + +GY LL L+A+ + +Q+ + ++S+IF ES RWL+ + +A++V+ + FN + ++ + +E+ E +L + ++ ++F K + + + +F + + YY ++ S S +FT L + + + +F C +LGR L+ L L + LFI +L + G + + I+V G F ++I+ E +PTV+R T+V + S AR ++S + + I+ LPI+ M + ++F + F+LPET ++P + L A NF+E
Sbjct: 203 EGILNIIGGCRWWQIWIYVLIALQQIPHAMFNLNVVYMMYDPEFQCMVPGFNDTNDTTISSHGPYLWGVDDIKNISFVFPNANSDGAYQRDSCYFYERSEERYRQLRRMPLETAMSEAWKDVAPKKKCQAYHFEKDVMVETIVTDFNLVCDSWFAKGHAHMFYSIGYLLGCVLGGIASDKIGRKPTIIGFGILSSMLGVF---LPFNDYYPMFLLIRLLSAICNEAADLAAYTLCMEITGTKYRAMVGSMLQAPWALGYALLALIAYLTKSWKTIQVIAAGLHFMSIIFICSIPESPRWLMVQNRVSEAEEVIRKACREPPFPFNMCTTSKCGNLPSDLELVSHRERKLNKKNGGKIGFLDLFTMKELRYRTISVCIVFMATALVYYGLVMALSDQSAPGRTLFTGYFHLNNGIAGAIEIPT-LFACVWMMQLGRKKALM-LTLITSGLFIIVAMLSMVSGHYMLALAFMYFGKIAVQGA-FNILYIFTSELYPTVVRNTAVGVTSMVARFGSGLSSYIALLSNIS---LPIVPMIIFAVFSLFAGMLV-FVLPETSEKPLPETLDDA-INFLE 765
BLAST of slc22a-6 vs. Ensembl Celegans
Match: K05F1.6 (pep chromosome:WBcel235:II:5782524:5787658:1 gene:WBGene00019408.1 transcript:K05F1.6c.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:K05F1.6) HSP 1 Score: 99.3673 bits (246), Expect = 2.534e-21 Identity = 136/574 (23.69%), Postives = 246/574 (42.86%), Query Frame = 1
Query: 238 EKIYQLVGGNSYFQYFILMFIFISQFNTAINILMPIFINNYQDVYCVLPK-NQTNQV-FTEHR------NQFKAIN------NETGFLIIDS-----------SRCRLTNISSICSEIFVKKYP-------------MTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGR---IIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAK-----FNRKSVTE-NQIDKYIEI--FEEERL-RSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDE---IFTA--ALISALGSLVSRSIYMFLC---KRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTM----AMFGSLCTFFLLPETFKRPSSDFLSQAEKNFVE 1773
E I ++GG ++Q +I + I + Q A+ L +++ + C++P N TN + H + K I+ N G DS + R + + SE + P M TI + F L C+ A + +G LG V GG+ SD GR IIG G+ M+ VF + +Y + L RL + + ++ + +EI R G + +GY LL L+A+ + +Q+ + ++S+IF ES RWL+ + +A++V+ + FN + ++ + +E+ E +L + ++ ++F K + + + +F + + YY ++ S S +FT L + + + +F C +LGR L+ L L + LFI +L + G + + I+V G F ++I+ E +PTV+R T+V + S AR ++S + + I+ LPI+ M + ++F + F+LPET ++P + L A NF+E
Sbjct: 203 EGILNIIGGCRWWQIWIYVLIALQQIPHAMFNLNVVYMMYDPEFQCMVPGFNDTNDTTISSHGPYLWGVDDIKNISFVFPNANSDGAYQRDSCYFYERSEERYRQLRRMPLETAMSEAWKDVAPKKKCQAYHFEKDVMVETIVTDFNLVCDSWFAKGHAHMFYSIGYLLGCVLGGIASDKIGRKPTIIGFGILSSMLGVF---LPFNDYYPMFLLIRLLSAICNEAADLAAYTLCMEITGTKYRAMVGSMLQAPWALGYALLALIAYLTKSWKTIQVIAAGLHFMSIIFICSIPESPRWLMVQNRVSEAEEVIRKACREPPFPFNMCTTSKCGNLPSDLELVSHRERKLNKKNGGKIGFLDLFTMKELRYRTISVCIVFMATALVYYGLVMALSDQSAPGRTLFTGYFHLNNGIAGAIEIPT-LFACVWMMQLGRKKALM-LTLITSGLFIIVAMLSMVSGHYMLALAFMYFGKIAVQGA-FNILYIFTSELYPTVVRNTAVGVTSMVARFGSGLSSYIALLSNIS---LPIVPMIIFAVFSLFAGMLV-FVLPETSEKPLPETLDDA-INFLE 765
BLAST of slc22a-6 vs. Ensembl Celegans
Match: K05F1.6 (pep chromosome:WBcel235:II:5782942:5787658:1 gene:WBGene00019408.1 transcript:K05F1.6a.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:K05F1.6) HSP 1 Score: 98.9821 bits (245), Expect = 2.959e-21 Identity = 137/575 (23.83%), Postives = 248/575 (43.13%), Query Frame = 1
Query: 238 EKIYQLVGGNSYFQYFILMFIFISQFNTAINILMPIFINNYQDVYCVLPK-NQTNQV-FTEHR------NQFKAIN------NETGFLIIDS-----------SRCRLTNISSICSEIFVKKYP-------------MTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGR---IIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAK-----FNRKSVTE-NQIDKYIEI--FEEERL-RSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDE---IFTAALISALGSLVSRSIY---MFLC---KRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTM----AMFGSLCTFFLLPETFKRPSSDFLSQAEKNFVE 1773
E I ++GG ++Q +I + I + Q A+ L +++ + C++P N TN + H + K I+ N G DS + R + + SE + P M TI + F L C+ A + +G LG V GG+ SD GR IIG G+ M+ VF + +Y + L RL + + ++ + +EI R G + +GY LL L+A+ + +Q+ + ++S+IF ES RWL+ + +A++V+ + FN + ++ + +E+ E +L + ++ ++F K + + + +F + + YY ++ S S +FT L + ++ +I +F C +LGR L+ L L + LFI +L + G + + I+V G F ++I+ E +PTV+R T+V + S AR ++S + + I+ LPI+ M + ++F + F+LPET ++P + L A NF+E
Sbjct: 201 EGILNIIGGCRWWQIWIYVLIALQQIPHAMFNLNVVYMMYDPEFQCMVPGFNDTNDTTISSHGPYLWGVDDIKNISFVFPNANSDGAYQRDSCYFYERSEERYRQLRRMPLETAMSEAWKDVAPKKKCQAYHFEKDVMVETIVTDFNLVCDSWFAKGHAHMFYSIGYLLGCVLGGIASDKIGRKPTIIGFGILSSMLGVF---LPFNDYYPMFLLIRLLSAICNEAADLAAYTLCMEITGTKYRAMVGSMLQAPWALGYALLALIAYLTKSWKTIQVIAAGLHFMSIIFICSIPESPRWLMVQNRVSEAEEVIRKACREPPFPFNMCTTSKCGNLPSDLELVSHRERKLNKKNGGKIGFLDLFTMKELRYRTISVCIVFMATALVYYGLVMALSDQSAPGRTLFTGYF--HLNNGIAGAIEIPTLFACVWMMQLGRKKALM-LTLITSGLFIIVAMLSMVSGHYMLALAFMYFGKIAVQGA-FNILYIFTSELYPTVVRNTAVGVTSMVARFGSGLSSYIALLSNIS---LPIVPMIIFAVFSLFAGMLV-FVLPETSEKPLPETLDDA-INFLE 763
BLAST of slc22a-6 vs. Ensembl Celegans
Match: K05F1.6 (pep chromosome:WBcel235:II:5782524:5787658:1 gene:WBGene00019408.1 transcript:K05F1.6a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:K05F1.6) HSP 1 Score: 98.9821 bits (245), Expect = 2.959e-21 Identity = 137/575 (23.83%), Postives = 248/575 (43.13%), Query Frame = 1
Query: 238 EKIYQLVGGNSYFQYFILMFIFISQFNTAINILMPIFINNYQDVYCVLPK-NQTNQV-FTEHR------NQFKAIN------NETGFLIIDS-----------SRCRLTNISSICSEIFVKKYP-------------MTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGR---IIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAK-----FNRKSVTE-NQIDKYIEI--FEEERL-RSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDE---IFTAALISALGSLVSRSIY---MFLC---KRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTM----AMFGSLCTFFLLPETFKRPSSDFLSQAEKNFVE 1773
E I ++GG ++Q +I + I + Q A+ L +++ + C++P N TN + H + K I+ N G DS + R + + SE + P M TI + F L C+ A + +G LG V GG+ SD GR IIG G+ M+ VF + +Y + L RL + + ++ + +EI R G + +GY LL L+A+ + +Q+ + ++S+IF ES RWL+ + +A++V+ + FN + ++ + +E+ E +L + ++ ++F K + + + +F + + YY ++ S S +FT L + ++ +I +F C +LGR L+ L L + LFI +L + G + + I+V G F ++I+ E +PTV+R T+V + S AR ++S + + I+ LPI+ M + ++F + F+LPET ++P + L A NF+E
Sbjct: 201 EGILNIIGGCRWWQIWIYVLIALQQIPHAMFNLNVVYMMYDPEFQCMVPGFNDTNDTTISSHGPYLWGVDDIKNISFVFPNANSDGAYQRDSCYFYERSEERYRQLRRMPLETAMSEAWKDVAPKKKCQAYHFEKDVMVETIVTDFNLVCDSWFAKGHAHMFYSIGYLLGCVLGGIASDKIGRKPTIIGFGILSSMLGVF---LPFNDYYPMFLLIRLLSAICNEAADLAAYTLCMEITGTKYRAMVGSMLQAPWALGYALLALIAYLTKSWKTIQVIAAGLHFMSIIFICSIPESPRWLMVQNRVSEAEEVIRKACREPPFPFNMCTTSKCGNLPSDLELVSHRERKLNKKNGGKIGFLDLFTMKELRYRTISVCIVFMATALVYYGLVMALSDQSAPGRTLFTGYF--HLNNGIAGAIEIPTLFACVWMMQLGRKKALM-LTLITSGLFIIVAMLSMVSGHYMLALAFMYFGKIAVQGA-FNILYIFTSELYPTVVRNTAVGVTSMVARFGSGLSSYIALLSNIS---LPIVPMIIFAVFSLFAGMLV-FVLPETSEKPLPETLDDA-INFLE 763
BLAST of slc22a-6 vs. Ensembl Celegans
Match: F32H5.4 (pep chromosome:WBcel235:V:13361203:13363357:1 gene:WBGene00009350.1 transcript:F32H5.4.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F32H5.4) HSP 1 Score: 96.6709 bits (239), Expect = 8.264e-21 Identity = 113/452 (25.00%), Postives = 211/452 (46.68%), Query Frame = 1
Query: 493 ISSICSEIFVKKYPMTSTIRSQFKLY---------CEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMI---SVFSTVAAVSPWYT-LHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKF--NRKSVTENQIDKYIEI---FEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLV-SRSIYMFLCK----RLGRVTILLSLQLGVTALFIASIILKYIYGGK---NIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAP-NVLPIIGMT-MAMFGSLCTFFLLPETFKRPSSDFLSQAEKN 1764
I IC F P TI S++ Y C A + S+ M+G+ +GSV G +D +GR+ + +FM+ S+ +T A ++T + + +F G +S V ++ + ++ F + + Y++L +A+ D Q A +S + F KES RWL+ + ++A++V+ HI + N + N+I++ ++ +EER++ + +F K + ++LW FS SF+ Y F+ K+S ++ AL+ +GSL +I+ L +LGR I L +L +T + + SI + Y + + ++I V ++A + + F + E +PTVIR ++VS S+ +R+ ++ Q+ F + P LP +T +F ++ LPET +P + + + KN
Sbjct: 78 IKDICKSSFDFHNPPNCTITSKYDFYSINVDYGHFCGEGAWVKTSISVQMVGVLIGSVTSGAVADRYGRLKVLSVCFFMVSSLSILNTFAKDLIYFTIIRTILSIFKGGLLSTYGV------YKMEHVPRQHRFWIATMISWAPNYMILSFVAYLCHDWITYQYAIFALSMPGAVVFLFVKESPRWLIQAGRIEEARQVLKHIMEVDGNTSDHSWNEIEEMLQTEKKRQEERIKK-RKNYDFRHLFWNKYMASVTMILWLGMFSTSFTNYGFVFNIEKLSGSLYINALL--MGSLRWVLNIFFGLADLKFAKLGRKHIHLISKLTIT-ICVFSIFVTYYFEYEEDYSLIIRVATLLASATASQVFITKSMVLMEFYPTVIRNSAVSFKSSASRIGTILGPQL---FILCPYKSLPYAILTGFCLFDAIAFQLRLPETKGKPLPETMPERHKN 516
BLAST of slc22a-6 vs. Ensembl Fly
Match: Orct (gene:FBgn0019952 transcript:FBtr0334870) HSP 1 Score: 134.035 bits (336), Expect = 7.542e-33 Identity = 127/523 (24.28%), Postives = 229/523 (43.79%), Query Frame = 1
Query: 274 FQYFILMFIFISQFNTAINILMPIFINNYQDVYCVLP-KNQTNQVFTEHRNQFKAINNET-GFLIID-------SSRCRLTNISSICSEIFVKKYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVT----ENQIDKYIEIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEKNFVEWRQPWRKSSK 1803
+Q I + + A + L +F+ D C LP +N + + H NE + +D S R +N + CS + ++ +++ L C LS+ + S+FMLG+ LGS+ G SD GR S + +F +AAV+P Y + + R+ G S F+ +ALE+V S R G + + +G++L A+FI D LQ+A + L + + ES RWLL + +A ++ AK N+ V E +D+ E +++ + + ++ ++ +Y + L+++F +F S YY ++ + +IS + ++ +F R GR +IL + +A+I ++ N + MI +++G ++I+ E FPTV+R + S ARV G++A ++ + EI LP+I + LLPET +P + + E NF + P + +
Sbjct: 16 YQKRIYYLLCLPAIVCAFHKLAGVFLLAKPDFRCALPYENGSIYELSPHLWNLSYPENERCSYYDVDYTEEYLNGSIPRSSNETKTCSSYVYDRSKYLNSAVTEWNLVCSRSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVLQLIFGVLAAVAPEYFSYTISRMIVGATTSGVFLVAYVIALEMVGSSYRLFAGVAMQMFFSVGFMLTAGFAYFIHDWRWLQIAITLPGLLFLCYYWIIPESARWLLMKGRKDEAFVIIEKAAKENKVEVPNEIYEQLVDEVAEKKKQDEMAASQPAATVFDLLRYPNLRRKTLLIFFDWFVNSGVYYGLSWNTNNLGGNQLVNFMISGAVEIPGYTLLLFTLNRWGRRSILCGTMMVAGISLLATI---FVPSDMNWLIVACAMIGKLAITSSYGTIYIFSAEQFPTVVRNVGLGASSMVARVGGILAPYLKLLGEIW-RPLPLIICGALSLTAGLLSLLLPETLNKPMPETIEDGE-NFGKKPAPQETAEE 533
BLAST of slc22a-6 vs. Ensembl Fly
Match: Orct (gene:FBgn0019952 transcript:FBtr0084599) HSP 1 Score: 134.035 bits (336), Expect = 7.542e-33 Identity = 127/523 (24.28%), Postives = 229/523 (43.79%), Query Frame = 1
Query: 274 FQYFILMFIFISQFNTAINILMPIFINNYQDVYCVLP-KNQTNQVFTEHRNQFKAINNET-GFLIID-------SSRCRLTNISSICSEIFVKKYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVT----ENQIDKYIEIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEKNFVEWRQPWRKSSK 1803
+Q I + + A + L +F+ D C LP +N + + H NE + +D S R +N + CS + ++ +++ L C LS+ + S+FMLG+ LGS+ G SD GR S + +F +AAV+P Y + + R+ G S F+ +ALE+V S R G + + +G++L A+FI D LQ+A + L + + ES RWLL + +A ++ AK N+ V E +D+ E +++ + + ++ ++ +Y + L+++F +F S YY ++ + +IS + ++ +F R GR +IL + +A+I ++ N + MI +++G ++I+ E FPTV+R + S ARV G++A ++ + EI LP+I + LLPET +P + + E NF + P + +
Sbjct: 16 YQKRIYYLLCLPAIVCAFHKLAGVFLLAKPDFRCALPYENGSIYELSPHLWNLSYPENERCSYYDVDYTEEYLNGSIPRSSNETKTCSSYVYDRSKYLNSAVTEWNLVCSRSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVLQLIFGVLAAVAPEYFSYTISRMIVGATTSGVFLVAYVIALEMVGSSYRLFAGVAMQMFFSVGFMLTAGFAYFIHDWRWLQIAITLPGLLFLCYYWIIPESARWLLMKGRKDEAFVIIEKAAKENKVEVPNEIYEQLVDEVAEKKKQDEMAASQPAATVFDLLRYPNLRRKTLLIFFDWFVNSGVYYGLSWNTNNLGGNQLVNFMISGAVEIPGYTLLLFTLNRWGRRSILCGTMMVAGISLLATI---FVPSDMNWLIVACAMIGKLAITSSYGTIYIFSAEQFPTVVRNVGLGASSMVARVGGILAPYLKLLGEIW-RPLPLIICGALSLTAGLLSLLLPETLNKPMPETIEDGE-NFGKKPAPQETAEE 533
BLAST of slc22a-6 vs. Ensembl Fly
Match: Orct2 (gene:FBgn0086365 transcript:FBtr0084598) HSP 1 Score: 131.724 bits (330), Expect = 5.296e-32 Identity = 133/533 (24.95%), Postives = 235/533 (44.09%), Query Frame = 1
Query: 235 SEKIYQLVGGNSYFQYFILMFIFISQFNTAINILMPIFINNYQDVYCVLP-KNQTNQVFTEHRNQFKAINNET-GFLIID-------SSRCRLTNISSICSEIFVKKYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFY---KESFRWLLATXXXXXXXXVMMHIAKFNRKSVT-----------ENQIDKYIEIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEI-APNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEK 1761
E I L G +Q I I ++ A + L +F+ D C LP +N ++ H NE + +D S R +N + CS + ++ +++ L C +++ + S+FMLG+ LGS+ G SD +GR S + +F +A V+P Y + RL G S F+ +A+E+V +R G + + + +G++L + A+F+ D LQ+A ++ LIF F+Y ES RWLL + A M A+FN+ ++ EN +K + E++ L S+ ++F Y + L+++ + S YY +S + + +IS + + + R GR +IL + +A++I+ + +L +AI+ S +G ++I+ E FPTV+R ++ S AR+SGM+A + ++ I P L I G + G LLPET +P + ++ E+
Sbjct: 4 DEAIIHL-GDFGRYQKIIYFLICLTSIPVAFHKLAGVFLLAKPDFRCALPFENGSSYDLPTHLWNLSYPENERCSYYDVDYTEEYLNGSIPRSSNETKTCSSYVYDRSKYLNSAVTEWNLVCGRDFMAATSDSLFMLGVLLGSIVFGQLSDKYGRKPILFASLVIQVLFGVLAGVAPEYFTYTFARLMVGATTSGVFLVAYVVAMEMVGPDKRLYAGIFVMMFFSVGFMLTAVFAYFVHDWRWLQIA---LTLPGLIFMFYYWIIPESARWLLLKGRKDCAIANMQKAARFNKVEISDEALSELLDEGENSEEKAKQKLEDQELDE-GPPPSVWDLFCYPNLRRKTLLIFLDWLVTSGVYYGLSWNTSNLGGNVLLNFVISGAVEIPAYIFLLLTLNRWGRRSILCGCLVMAGLSLLATVIIPQRMHTLIVACAMLGKLAITAS---YGTVYIFSAEQFPTVVRNVALGAASMVARISGMMAPFLNFLATIWKPLPLLICGSLTLVAGL--LSLLLPETHNKPMLETIADGER 526
BLAST of slc22a-6 vs. Ensembl Fly
Match: Orct2 (gene:FBgn0086365 transcript:FBtr0334869) HSP 1 Score: 131.724 bits (330), Expect = 5.296e-32 Identity = 133/533 (24.95%), Postives = 235/533 (44.09%), Query Frame = 1
Query: 235 SEKIYQLVGGNSYFQYFILMFIFISQFNTAINILMPIFINNYQDVYCVLP-KNQTNQVFTEHRNQFKAINNET-GFLIID-------SSRCRLTNISSICSEIFVKKYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFY---KESFRWLLATXXXXXXXXVMMHIAKFNRKSVT-----------ENQIDKYIEIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEI-APNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEK 1761
E I L G +Q I I ++ A + L +F+ D C LP +N ++ H NE + +D S R +N + CS + ++ +++ L C +++ + S+FMLG+ LGS+ G SD +GR S + +F +A V+P Y + RL G S F+ +A+E+V +R G + + + +G++L + A+F+ D LQ+A ++ LIF F+Y ES RWLL + A M A+FN+ ++ EN +K + E++ L S+ ++F Y + L+++ + S YY +S + + +IS + + + R GR +IL + +A++I+ + +L +AI+ S +G ++I+ E FPTV+R ++ S AR+SGM+A + ++ I P L I G + G LLPET +P + ++ E+
Sbjct: 4 DEAIIHL-GDFGRYQKIIYFLICLTSIPVAFHKLAGVFLLAKPDFRCALPFENGSSYDLPTHLWNLSYPENERCSYYDVDYTEEYLNGSIPRSSNETKTCSSYVYDRSKYLNSAVTEWNLVCGRDFMAATSDSLFMLGVLLGSIVFGQLSDKYGRKPILFASLVIQVLFGVLAGVAPEYFTYTFARLMVGATTSGVFLVAYVVAMEMVGPDKRLYAGIFVMMFFSVGFMLTAVFAYFVHDWRWLQIA---LTLPGLIFMFYYWIIPESARWLLLKGRKDCAIANMQKAARFNKVEISDEALSELLDEGENSEEKAKQKLEDQELDE-GPPPSVWDLFCYPNLRRKTLLIFLDWLVTSGVYYGLSWNTSNLGGNVLLNFVISGAVEIPAYIFLLLTLNRWGRRSILCGCLVMAGLSLLATVIIPQRMHTLIVACAMLGKLAITAS---YGTVYIFSAEQFPTVVRNVALGAASMVARISGMMAPFLNFLATIWKPLPLLICGSLTLVAGL--LSLLLPETHNKPMLETIADGER 526
BLAST of slc22a-6 vs. Ensembl Fly
Match: CG8654 (gene:FBgn0034479 transcript:FBtr0086340) HSP 1 Score: 125.561 bits (314), Expect = 3.489e-30 Identity = 116/431 (26.91%), Postives = 196/431 (45.48%), Query Frame = 1
Query: 478 CRLTNI----SSICSEIFVKKYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQIDKYIEIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAE 1758
C+ N+ S CSE STI +++ L CE L+S + S+ MLGI GS+ G+F+D +GR FM + + VSP+Y + L R A + + ++ + +EIV +R + + ++IG+ L L A+FIR+ Q + S V +I+ + ES RWL T K K+ K++ IAK N K+ TE + + R + ++ ++F+ + + + + + YY S + IF + I+A + + + K LGR LL L G +AL + I+L + + I + + F +++YGGE FPTV+R++ V + S R+ ++A + + V P+I ++ L T F LPET P + L E
Sbjct: 67 CKTENVTDPCSDECSETEFDTSVFQSTIITEWNLTCESKQLASLSQSIVMLGILFGSILFGMFADRYGRRPAFLTCCFMQLITGLIVCVSPYYWFYCLFRFLVAVATAGTMTTSFVLLMEIVGPKKREMVAILYQIPFNIGHASLALFAYFIREWRWFQFSITIFSIVFVIYIWLVPESPRWLFTTGKLDKSIKILEKIAKCN-KAPTETIRPEIEAAYGALAARQPVKKGTVVDLFRTPYMRIKTIFMANNWLVVCMVYYGTAQYVSALGGNIFISNAIAAGVGIPGTCLCALMTKYLGRKKTLL-LSNGCSALGL--ILLACLSTQAEAVRVTCATIGLFGASITFPNVYLYGGELFPTVVRSSGVGLCSMVGRIGSIVAPLIVDLAAYGLWVAPLIFGIFSILAMLGTIF-LPETRGTPLPETLEDGE 492
BLAST of slc22a-6 vs. Ensembl Zebrafish
Match: slc22a7a (solute carrier family 22 member 7a [Source:ZFIN;Acc:ZDB-GENE-050506-52]) HSP 1 Score: 129.413 bits (324), Expect = 4.187e-31 Identity = 132/530 (24.91%), Postives = 237/530 (44.72%), Query Frame = 1
Query: 238 EKIYQLVGGNSYFQYFILMFIFISQFNTAINILMPIFINNYQDVYCVLPKNQ----TNQVFTEHRNQFKAIN---NETGFLIIDSSRCRL--------------------TNISSICSEIFV-KKYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQID----KYIEIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVT-ILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQM---EWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPET 1719
E + + +GG + FQ+ +L +++ + ++ L+ FI+ +C LP+ + E Q A+ N G S C++ +N+S C +V + TST +++ L C+ L+ + F +G+ +G+V G SD FGR +S+ +VF + A S Y + A+ R GFA++ ++ + +E ++ RT G SLG+ +G +LL LLA+ IRD L L V +I ++ ES RWLLA + ++A+K +++ AK N K ++D K I I E+ ++ S+ + + K + +++ + W F+ +F+YY + I+ I + + ++ R+GR SL + + + S+I + T + +I S F ++Y E +PTV+R + S AR+ G +A + E ++ P P++ A+F S C FLLPET
Sbjct: 4 EDVLREIGGFNKFQFLVLYILWLPRVILPLHFLLHNFISGVPPHHCALPRLDGRFSASGAEKEELAQIVALGIPRNSDG----SYSSCKMYTMPMDFDLNGDLSVLYGNRSNVSVPCQNGWVYDRSQFTSTTATEWDLVCDNKKLNQALATFFFIGVTMGAVVFGQLSDKFGRKPMIQVSFVSSAVFGIIEAFSSSYVMFAIARTLCGFALTGMSITTVALCVEWTDVKHRTFTGTIISLGWSVGNMLLALLAYLIRDWRHLILVVTSPCLVGIIAWWWIPESARWLLANGRVEEAQKYLINCAKMNGKYSYTKKLDIENLKKITIAEDSN-KNHSY-LDLVRTPKLRKIVLCSGIFW---FAVAFTYYGISFNITGFGLNIYLTQFIYGVIEVPAKVGTYLTLDRIGRRNGQAWSLIIAGALIGLNSVIPTEFAA----VRTGIAVIGKGFSEAAFTIAFLYTSELYPTVLRQCGLGYTSFIARIGGSLAPMVILFEDIWHYGP---PVVFSATAVF-SGCVVFLLPET 516
BLAST of slc22a-6 vs. Ensembl Zebrafish
Match: si:dkey-166k12.1 (si:dkey-166k12.1 [Source:ZFIN;Acc:ZDB-GENE-120215-78]) HSP 1 Score: 126.331 bits (316), Expect = 3.131e-30 Identity = 106/420 (25.24%), Postives = 201/420 (47.86%), Query Frame = 1
Query: 541 STIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTEN-QIDKYIEIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFL--CKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGS-----LCTFFLLPETFKRPSSDFLSQAEKNFVEW 1776
ST +++ L C+ LSS +S++MLG+ +G+V G +D +GR +S + +VF AA +P + ++ R G VS ++ + E +R G + + GY+LL +AF IRD KLQLA ++ + + + S RWLL + ++A ++ A N +++ Q+++Y E + RS + ++ ++ + + L+L++I+F YY LG S + +++ + L + +R++ + L C R +++ L + G A ++ + + T L M+ +F +++Y E FPTV+R T + + S AR+ G++A + + P V+P M +FGS LPET ++P D + EK+ +++
Sbjct: 96 STTVTEWDLVCDKRGLSSLGSSIYMLGLLVGAVVFGAMADRYGRRFAMLVSLALQTVFGVAAAFAPNFPVYVGLRFIIGMTVSGVIINAFVLGTEWTCTQRRMLAGIFTDYFFGFGYMLLAGVAFLIRDWRKLQLAISAPGFLFIFYIWVLPHSARWLLVNNRKEEAIDLLRKAASVNGRTLPPTVQVERY----ESPQGRS---KYTVVDLLRTPQMRKRALILFYIWFVNVLVYYGLSLGVSDLGADLYLTQFMFGLVEIPARTLVLVLLPCSRKIPLSVFLVVGGG------ACLLTLTLPADSAHVRTALAMVGKFGITASFAIIYVYSAELFPTVLRQTGIGVSSMFARMGGVLAPLINLLGRHTP-VVP-----MLIFGSTPLLAAALALALPETARQPLPDSIHDTEKSTLKY 496
BLAST of slc22a-6 vs. Ensembl Zebrafish
Match: oatx (organic anion transporter X [Source:ZFIN;Acc:ZDB-GENE-070115-1]) HSP 1 Score: 126.331 bits (316), Expect = 4.408e-30 Identity = 100/383 (26.11%), Postives = 188/383 (49.09%), Query Frame = 1
Query: 628 LGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRK-SVTENQIDKYIEIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKN--IITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEKNF 1767
L S+ GGVFS FGR SYF +++ + A++P Y ++ + R TG +VS ++ + +E + RT G S + G ++L +A+ +RD K+Q+A C ++ ++ +++ ES RWL+ + ++A K++ +AK N K +TE + +E ++ ++S ++ ++ + + + L ++FS SF+YY + K I+ +I ++ + + + LGR L G L ASII I+ ++ + T L ++ + +F ++++ GE +PTVIR T + S +R+ M A + + +I P + I+ A+ L FLLPET P D + E+ +
Sbjct: 150 LNSIPGGVFSCRFGRKALLIWSYFQLALLGSFTALAPSYVVYCIFRFLTGMSVSGVILNAVSLKVEWIPTKTRTLVGTLSSFFFTFGQMVLAGVAYSLRDWRKIQMAVCLPFFIFFMYSWWFSESARWLVLNGRSEEALKLLHRVAKINGKPEMTEKITLEELESHMQKEVQSSKSIYTVFDLLRTPTMRKISMCLMVVWFSTSFAYYGLAMDLQKFGVNIYLMQVIFGAVDFPAKLVALLMLSFLGR-----RLTQGACLLVSASIIFANIFVPEDMQVTRTALAVLGKGFTSASFTCVYLFTGELYPTVIRQTGMGFVSTMSRIGSMAAPAVLILDDILPALPSIVYGGSAVIAGLIA-FLLPETLNIPLPDTIDDVEEKW 526
BLAST of slc22a-6 vs. Ensembl Zebrafish
Match: si:dkey-166k12.1 (si:dkey-166k12.1 [Source:ZFIN;Acc:ZDB-GENE-120215-78]) HSP 1 Score: 125.561 bits (314), Expect = 5.535e-30 Identity = 106/420 (25.24%), Postives = 201/420 (47.86%), Query Frame = 1
Query: 541 STIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTEN-QIDKYIEIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFL--CKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGS-----LCTFFLLPETFKRPSSDFLSQAEKNFVEW 1776
ST +++ L C+ LSS +S++MLG+ +G+V G +D +GR +S + +VF AA +P + ++ R G VS ++ + E +R G + + GY+LL +AF IRD KLQLA ++ + + + S RWLL + ++A ++ A N +++ Q+++Y E + RS + ++ ++ + + L+L++I+F YY LG S + +++ + L + +R++ + L C R +++ L + G A ++ + + T L M+ +F +++Y E FPTV+R T + + S AR+ G++A + + P V+P M +FGS LPET ++P D + EK+ +++
Sbjct: 109 STTVTEWDLVCDKRGLSSLGSSIYMLGLLVGAVVFGAMADRYGRRFAMLVSLALQTVFGVAAAFAPNFPVYVGLRFIIGMTVSGVIINAFVLGTEWTCTQRRMLAGIFTDYFFGFGYMLLAGVAFLIRDWRKLQLAISAPGFLFIFYIWVLPHSARWLLVNNRKEEAIDLLRKAASVNGRTLPPTVQVERY----ESPQGRS---KYTVVDLLRTPQMRKRALILFYIWFVNVLVYYGLSLGVSDLGADLYLTQFMFGLVEIPARTLVLVLLPCSRKIPLSVFLVVGGG------ACLLTLTLPADSAHVRTALAMVGKFGITASFAIIYVYSAELFPTVLRQTGIGVSSMFARMGGVLAPLINLLGRHTP-VVP-----MLIFGSTPLLAAALALALPETARQPLPDSIHDTEKSTLKY 509
BLAST of slc22a-6 vs. Ensembl Zebrafish
Match: slc22a6l (solute carrier family 22 member 6, like [Source:NCBI gene;Acc:404609]) HSP 1 Score: 122.479 bits (306), Expect = 7.658e-29 Identity = 114/433 (26.33%), Postives = 207/433 (47.81%), Query Frame = 1
Query: 535 MTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQIDKYIEIFEEERLRSVS---HRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIIL---KYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEKNFVEWRQPWRKSSKKIID 1815
M+STI +++ L C+Y AL + + +M G+ +G++ G SD FGR + +S M+++ T A S +T+ + R+ G A+S +++ + +E + RT G Y G L+L +A+ IRD L LA YVS ++ +++ ES RWL+ TKK ++A K + +A+ N +S ++ID +E+ +E + ++ S ++ + + + L ++FS SF+YY + K I+ +I + ++ I LGR Q G AL +A I++ + ++ T L +I +F ++Y GE +PTVIR + + S AR M+A + + + P + I + + FF LPET +P D + + + R +SK++ +
Sbjct: 124 MSSTIITEWDLVCDYRALKQMSQTTYMGGVLVGAIVFGGLSDRFGRRVLLLISNLMMAIGGTCVAFSTSFTMFCVFRVCCGMALSGLVLNSFSLIVEWIPTRVRTVVGTGTGYCYTTGQLILAAVAYCIRDWRWLTLAVSLPFYVSFLYSWWFLESARWLVLTKKPEQAVKNLKTVARINGRSAEGDKID--LEMLQESMKKEMACSKGSYSALDLLRTSTMRTITICLSAVWFSTSFAYYGLSMDLQKFGVSIYLIQIIFGAVDIPAKIIVTICMSMLGR----RPSQCG--ALVLAGIMILINLLVPSDLQMLRTSLAVIGKGCLAASFNCCYLYAGELYPTVIRQSGMGWVSMMARFGAMVAPMVLLLGDDYPWIPGFIYGGAPIVSGIFAFF-LPETLSQPLPDTIQDIDDRGLA-----RTNSKRLPE 542
BLAST of slc22a-6 vs. Ensembl Xenopus
Match: ENSXETT00000036038.1 (solute carrier family 22 (organic anion transporter), member 8 [Source:NCBI gene;Acc:100490266]) HSP 1 Score: 134.035 bits (336), Expect = 1.525e-32 Identity = 127/453 (28.04%), Postives = 215/453 (47.46%), Query Frame = 1
Query: 526 KYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQIDKYIEIFEEE---RLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISAL----GSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSG---TNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEKNFVEWRQPWRKSSKKIIDTEIKV*HEYSVFE 1854
K +STI +++ L C A S++M G+ +G++ G SD +GR SYF ++V AA SP Y + + R TG A+S ++ + + +E V RT G Y G LLL LA+ +RD LQL ++ ++ +++ ES RWL+ + K +KA K + +A N K +I +E + E L S S+ ++ + + L ++FS SF+YY + K + I+ +I LVS + +++ ++ T +SL LG A+ IA+I + N + TV +A+ G +F +++Y E +PTVIR + + + S AR+ G++A ++ + E+ P V +I + LC FF LPET +P D + + EK P ++ K +D+ + E V E
Sbjct: 118 KDEFSSTIITEWDLVCGRKTRRQLAQSIYMGGVLVGAIILGGLSDRYGRRALLIWSYFQLAVSGVCAAFSPNYLSYCIFRFLTGMALSGIGLNTTALIVEWVPTRVRTVTGTLAGFSYTAGQLLLAGLAYGMRDWRWLQLCVSLPFFIYFLYAWWFPESARWLVLSGKPEKAVKEIRKVANLNGKKEEGEKIT--LESLKSEMIKELASAKSSYSVIDLVRTNTIRRISCALSLVWFSTSFAYYGLAMDLQKFNVSIYLIQVIFGAVDFPAKLVSATAMIYVGRKF---TQFMSLILGGIAI-IANIFV------PNELQTVRTSLAVFGKGCLAASFSCIFLYTTELYPTVIRQSGLGMCSTMARIGGIVAPLVKILGELYPFVPLLIYGGAPIISGLCVFF-LPETVNKPLPDTIEEVEKGI---NAPKKEIEKNEMDSLKRGMKENPVNE 554
BLAST of slc22a-6 vs. Ensembl Xenopus
Match: ENSXETT00000036031.1 (solute carrier family 22 (organic anion transporter), member 8 [Source:NCBI gene;Acc:100490266]) HSP 1 Score: 132.494 bits (332), Expect = 3.924e-32 Identity = 121/426 (28.40%), Postives = 206/426 (48.36%), Query Frame = 1
Query: 526 KYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQIDKYIEIFEEE---RLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISAL----GSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSG---TNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEKNFVE 1773
K +STI +++ L C A S++M G+ +G++ G SD +GR SYF ++V AA SP Y + + R TG A+S ++ + + +E V RT G Y G LLL LA+ +RD LQL ++ ++ +++ ES RWL+ + K +KA K + +A N K +I +E + E L S S+ ++ + + L ++FS SF+YY + K + I+ +I LVS + +++ ++ T +SL LG A+ IA+I + N + TV +A+ G +F +++Y E +PTVIR + + + S AR+ G++A ++ + E+ P V +I + LC FF LPET +P D + + EK ++
Sbjct: 118 KDEFSSTIITEWDLVCGRKTRRQLAQSIYMGGVLVGAIILGGLSDRYGRRALLIWSYFQLAVSGVCAAFSPNYLSYCIFRFLTGMALSGIGLNTTALIVEWVPTRVRTVTGTLAGFSYTAGQLLLAGLAYGMRDWRWLQLCVSLPFFIYFLYAWWFPESARWLVLSGKPEKAVKEIRKVANLNGKKEEGEKIT--LESLKSEMIKELASAKSSYSVIDLVRTNTIRRISCALSLVWFSTSFAYYGLAMDLQKFNVSIYLIQVIFGAVDFPAKLVSATAMIYVGRKF---TQFMSLILGGIAI-IANIFV------PNELQTVRTSLAVFGKGCLAASFSCIFLYTTELYPTVIRQSGLGMCSTMARIGGIVAPLVKILGELYPFVPLLIYGGAPIISGLCVFF-LPETVNKPLPDTIEEVEKGELD 530
BLAST of slc22a-6 vs. Ensembl Xenopus
Match: ENSXETT00000022873.1 (solute carrier family 22 (organic anion transporter), member 8 [Source:NCBI gene;Acc:100490266]) HSP 1 Score: 132.494 bits (332), Expect = 5.038e-32 Identity = 121/423 (28.61%), Postives = 204/423 (48.23%), Query Frame = 1
Query: 526 KYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQIDKYIEIFEEE---RLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISAL----GSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSG---TNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEKN 1764
K +STI +++ L C A S++M G+ +G++ G SD +GR SYF ++V AA SP Y + + R TG A+S ++ + + +E V RT G Y G LLL LA+ +RD LQL ++ ++ +++ ES RWL+ + K +KA K + +A N K +I +E + E L S S+ ++ + + L ++FS SF+YY + K + I+ +I LVS + +++ ++ T +SL LG A+ IA+I + N + TV +A+ G +F +++Y E +PTVIR + + + S AR+ G++A ++ + E+ P V +I + LC FF LPET +P D + + EK
Sbjct: 118 KDEFSSTIITEWDLVCGRKTRRQLAQSIYMGGVLVGAIILGGLSDRYGRRALLIWSYFQLAVSGVCAAFSPNYLSYCIFRFLTGMALSGIGLNTTALIVEWVPTRVRTVTGTLAGFSYTAGQLLLAGLAYGMRDWRWLQLCVSLPFFIYFLYAWWFPESARWLVLSGKPEKAVKEIRKVANLNGKKEEGEKIT--LESLKSEMIKELASAKSSYSVIDLVRTNTIRRISCALSLVWFSTSFAYYGLAMDLQKFNVSIYLIQVIFGAVDFPAKLVSATAMIYVGRKF---TQFMSLILGGIAI-IANIFV------PNELQTVRTSLAVFGKGCLAASFSCIFLYTTELYPTVIRQSGLGMCSTMARIGGIVAPLVKILGELYPFVPLLIYGGAPIISGLCVFF-LPETVNKPLPDTIEEVEKG 527
BLAST of slc22a-6 vs. Ensembl Xenopus
Match: ENSXETT00000022866.1 (solute carrier family 22 (organic anion transporter), member 8 [Source:NCBI gene;Acc:100490266]) HSP 1 Score: 128.257 bits (321), Expect = 1.242e-30 Identity = 121/426 (28.40%), Postives = 206/426 (48.36%), Query Frame = 1
Query: 526 KYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQIDKYIEIFEEE---RLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISAL----GSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSG---TNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEKNFVE 1773
K +STI +++ L C A S++M G+ +G++ G SD +GR SYF ++V AA SP Y + + R TG A+S ++ + + +E V RT G Y G LLL LA+ +RD LQL ++ ++ +++ ES RWL+ + K +KA K + +A N K +I +E + E L S S+ ++ + + L ++FS SF+YY + K + I+ +I LVS + +++ ++ T +SL LG A+ IA+I + N + TV +A+ G +F +++Y E +PTVIR + + + S AR+ G++A ++ + E+ P V +I + LC FF LPET +P D + + K+ V+
Sbjct: 118 KDEFSSTIITEWDLVCGRKTRRQLAQSIYMGGVLVGAIILGGLSDRYGRRALLIWSYFQLAVSGVCAAFSPNYLSYCIFRFLTGMALSGIGLNTTALIVEWVPTRVRTVTGTLAGFSYTAGQLLLAGLAYGMRDWRWLQLCVSLPFFIYFLYAWWFPESARWLVLSGKPEKAVKEIRKVANLNGKKEEGEKIT--LESLKSEMIKELASAKSSYSVIDLVRTNTIRRISCALSLVWFSTSFAYYGLAMDLQKFNVSIYLIQVIFGAVDFPAKLVSATAMIYVGRKF---TQFMSLILGGIAI-IANIFV------PNELQTVRTSLAVFGKGCLAASFSCIFLYTTELYPTVIRQSGLGMCSTMARIGGIVAPLVKILGELYPFVPLLIYGGAPIISGLCVFF-LPETVNKPLPDTIEE-HKDIVK 529
BLAST of slc22a-6 vs. Ensembl Xenopus
Match: ENSXETT00000046179.1 (solute carrier family 22 member 20, pseudogene gene1 [Source:NCBI gene;Acc:100489586]) HSP 1 Score: 119.783 bits (299), Expect = 7.503e-28 Identity = 113/454 (24.89%), Postives = 207/454 (45.59%), Query Frame = 1
Query: 487 TNISSICSEIFV-KKYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGR---IIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQIDKYIEIFE-EERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIF----TAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEKNFVEWRQPWRKSSKKIIDTE 1821
TN + C + +V K +STI +++ L C+ + A S++M G+ +G+V G SD GR +IG S +++V T AA P + + R G A S ++ + + LE RT G ++ G+ G +LL LA+ IR+ LQ A Y ++ + ES RWL+ + +A K + +A N K ++ + I I + L V S+ ++F+ + + L ++FS ++Y + IF T I +V+ + ++ +R+ + T+L+ L AL + +I G I+ VL + +F +++ GE FPTVIR T + + + ARV ++A + ++EI+P +LP +A + L ET + + + + E ++ ++P +K + D +
Sbjct: 98 TNHTEPCEDGWVYDKSDFSSTIVTEWDLVCKLRKMRQIAQSIYMAGVLVGAVLLGGLSDRLGRRALLIG---SNLVMAVCGTCAAFLPNFITYCTFRCLCGIAFSGITLNTNSLILEWTPPKGRTIMGTLFAAGFTCGQILLAALAYGIREWRWLQFAVSAPFYFFFLYSWLVPESARWLILKGRSHEALKALQRVAIINGKREEGQKLSEMILISHMQSELNQVKRPHSLFDLFRTPGMRKVTICLMMVWFSSGVAFYGLGMDLQNFGISIFLLQFTFGAIDMPAKVVAALLMTYMGRRVTQATVLI---LSGVALLTNA----FIPQGMKILRMVLAVFGKGCMAASFACAYLFSGELFPTVIRQTGMGVVAMMARVGSVVAPLVLLLWEISP-ILPSAIYGIAAIIAGGAATFLMETNNQQLPESVEEVEASYQLIKEPKKKKNNHYEDIQ 540
BLAST of slc22a-6 vs. Ensembl Mouse
Match: Slc22a6 (solute carrier family 22 (organic anion transporter), member 6 [Source:MGI Symbol;Acc:MGI:892001]) HSP 1 Score: 130.954 bits (328), Expect = 9.734e-32 Identity = 109/423 (25.77%), Postives = 199/423 (47.04%), Query Frame = 1
Query: 487 TNISSICSEIFV-KKYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQIDKYIEIFE---EERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTI-LLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSD 1740
T ++ C + +V STI +++ L C + A A S+FM+G+ LG++ G +D GR L+Y +V T AA +P YT++ + RL +G +++ ++ + +E + I R G Y +G LL +A+ + LQLA +V+ I+ +F+ ES RW ++ + + + +A+ N K E IE+ + ++ L + S E+ + + L L ++F+ SF+YY ++ ++ +I L ++ + + +GR L SL L + + II + G II T L ++ ++F +++Y GE +PT+IR T + +GS ARV +++ + E P++ I + + S T LLPET +P D
Sbjct: 93 TGVTEPCLDGWVYDNSTFPSTIVTEWNLVCSHRAFRQLAQSLFMVGVLLGAMMFGYLADRLGRRKVLILNYLQTAVSGTCAAYAPNYTVYCIFRLLSGMSLASIAINCMTLNMEWMPIHTRAYVGTLIGYVYSLGQFLLAGIAYAVPHWRHLQLAVSVPFFVAFIYSWFFIESARWYSSSGRLDLTLRALQRVARINGKQ--EEGAKLSIEVLQTSLQKELTLNKGQASAMELLRCPTLRRLFLCLSMLWFATSFAYYGLVMDLQGFGVSMYLIQVIFGAVDLPAKFVCFLVINSMGRRPAQLASLLLAGICILVNGIIPR----GHTIIRTSLAVLGKGCLASSFNCIFLYTGELYPTMIRQTGLGMGSTMARVGSIVSPLISMTAEFYPSIPLFIFGAVPVAASAVT-ALLPETLGQPLPD 508
BLAST of slc22a-6 vs. Ensembl Mouse
Match: Slc22a7 (solute carrier family 22 (organic anion transporter), member 7 [Source:MGI Symbol;Acc:MGI:1859559]) HSP 1 Score: 126.331 bits (316), Expect = 4.054e-30 Identity = 128/532 (24.06%), Postives = 233/532 (43.80%), Query Frame = 1
Query: 238 EKIYQLVGGNSYFQYFILMFIFISQFNTAINILMPIFINNYQDVYCVLPKNQTN----------QVFTEHRNQF---------KAINNET-GFLIIDSSRCRLTNISSICSEIF-VKKYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQIDKYI--EIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEKN 1764
E++ VGG FQ L+ + + +F ++ L+PIF+ +C LP N + E F +A+ N T G + +S ++ CS+ + + +STI +++ L C+ L+ ++ F +G+ LG+V G SD FGR ++Y ++A S Y + R+ TG A++ + + LE +++ RT G + + G LLL L+ + IR L LA +I ++ ES RWLL + ++AKK + AK N + ++E+ + + ++ ER VS R S ++F+ + L ++F +FSYY L +S + ++ L+ + S+ FL + +GR + L F S++ + T L++I + S F +++ E +PTV+R T + + R+ +A + + + +LP + F + CT LLPET K + + E+
Sbjct: 4 EELLHKVGGFGPFQLRNLVLLALPRFLLPMHFLLPIFMAAVPAHHCALPDAPANLSHQDLWLKTHLPRETDGSFSSCLRFAYPQALPNVTLGTEVYNSGEPEGEPLTVPCSQGWEYDRSEFSSTIATEWDLVCQQRGLNKVTSTCFFIGVLLGAVVYGYLSDRFGRRRLLLVAYVSTLALGLMSAASVNYIMFVTTRMLTGSALAGFTIIVLPLELEWLDVEHRTVAGVISTTFWTGGVLLLTLVGYLIRSWRWLLLAATLPCVPGIISIWWVPESARWLLTQGRVEEAKKYLSICAKLNGRPISEDSLSQEALNKVITMER---VSQRPSYLDLFRTSQLRHVSLCCMMMWFGVNFSYYGLTLDASGLGLTVYQTQLLFGAVEVPSKITVFFLVRLVGRRLTEAGMLLATALTFGISLL---VSSDTKSWITALVVIGKAFSEAAFTTAYLFTSELYPTVLRQTGMGFTALIGRLGASLAPLVV-LLDGVWLLLPKLAYGGISFLAACTVLLLPETKKAQLPETIQDVERK 528
BLAST of slc22a-6 vs. Ensembl Mouse
Match: Slc22a8 (solute carrier family 22 (organic anion transporter), member 8 [Source:MGI Symbol;Acc:MGI:1336187]) HSP 1 Score: 119.783 bits (299), Expect = 5.709e-28 Identity = 130/530 (24.53%), Postives = 235/530 (44.34%), Query Frame = 1
Query: 241 KIYQLVGGNSYFQYFILMFIFISQFNTAINILMPIFINNYQDVYCVLPKNQTNQVFTEHRNQFKAINNETGFLIIDSSRCRLTNISSICSEIFVKKYPMTS---TIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQR----TNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFN-RKSVTENQIDKYIEIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEKNFVEWRQPWRKSSKK 1806
+I VG FQY + + + A + L+ IF D +C P N + + + E + L N + +E + + S TI +++ L C + L A S+FM GI +G G SD FGR SY +++ + AA SP T++ + R G ++S +S + +E V S R T G+ Y IG +L LA+ + LQL+ ++ + ++ ES RWL+ + K+ KA K + +A FN +K E + ++ ++ + S + + ++F+ ++ L +F+ F+YY+ +G + I+ +I + ++ I + LGR I L + + I ++I ++ ++ T L + +F +++Y E +PTV+R T + I + ARV MIA ++ E+ P + +I TM + G FFLL ET RP L + ++ +W Q +K+ ++
Sbjct: 5 EILDRVGSMGPFQYLHVTLLALPILGIANHNLLQIFTATTPDHHCRPPPNASLEPWVLPLGPNG--KPEKCLRFVHLPNASLPNDTQGATEPCLDGWIYNSTRDTIVTEWDLVCGSNKLKEMAQSVFMAGILVGGPVFGELSDRFGRKPILTWSYLLLAASGSSAAFSPSLTVYMIFRFLCGCSISGISLSTIILNVEWVPTSTRAISSTTIGYC----YTIGQFILPGLAYAVPQWRWLQLSVSAAFFIFSLLSWWVPESIRWLVLSGKFSKALKTLQRVATFNGKKEEGEKLTVEELKFNLQKDITSAKVKYGLSDLFRVSILRRVTFCLSLAWFATGFAYYSLAMGVEEFGVNIYILQIIFGGVDIPAKFITILSISYLGR-RITQGFLLILAGVAILALI--FVSSEMQLLRTALAVFGKGCLSGSFSCLFLYTSELYPTVLRQTGMGISNIWARVGSMIAPLVKITGELQPFIPNVIFGTMTLLGGSAAFFLL-ETLNRP----LPETIEDIQDWYQQTKKTKQE 520
BLAST of slc22a-6 vs. Ensembl Mouse
Match: Slc22a8 (solute carrier family 22 (organic anion transporter), member 8 [Source:MGI Symbol;Acc:MGI:1336187]) HSP 1 Score: 119.783 bits (299), Expect = 5.709e-28 Identity = 130/530 (24.53%), Postives = 235/530 (44.34%), Query Frame = 1
Query: 241 KIYQLVGGNSYFQYFILMFIFISQFNTAINILMPIFINNYQDVYCVLPKNQTNQVFTEHRNQFKAINNETGFLIIDSSRCRLTNISSICSEIFVKKYPMTS---TIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQR----TNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFN-RKSVTENQIDKYIEIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEKNFVEWRQPWRKSSKK 1806
+I VG FQY + + + A + L+ IF D +C P N + + + E + L N + +E + + S TI +++ L C + L A S+FM GI +G G SD FGR SY +++ + AA SP T++ + R G ++S +S + +E V S R T G+ Y IG +L LA+ + LQL+ ++ + ++ ES RWL+ + K+ KA K + +A FN +K E + ++ ++ + S + + ++F+ ++ L +F+ F+YY+ +G + I+ +I + ++ I + LGR I L + + I ++I ++ ++ T L + +F +++Y E +PTV+R T + I + ARV MIA ++ E+ P + +I TM + G FFLL ET RP L + ++ +W Q +K+ ++
Sbjct: 5 EILDRVGSMGPFQYLHVTLLALPILGIANHNLLQIFTATTPDHHCRPPPNASLEPWVLPLGPNG--KPEKCLRFVHLPNASLPNDTQGATEPCLDGWIYNSTRDTIVTEWDLVCGSNKLKEMAQSVFMAGILVGGPVFGELSDRFGRKPILTWSYLLLAASGSSAAFSPSLTVYMIFRFLCGCSISGISLSTIILNVEWVPTSTRAISSTTIGYC----YTIGQFILPGLAYAVPQWRWLQLSVSAAFFIFSLLSWWVPESIRWLVLSGKFSKALKTLQRVATFNGKKEEGEKLTVEELKFNLQKDITSAKVKYGLSDLFRVSILRRVTFCLSLAWFATGFAYYSLAMGVEEFGVNIYILQIIFGGVDIPAKFITILSISYLGR-RITQGFLLILAGVAILALI--FVSSEMQLLRTALAVFGKGCLSGSFSCLFLYTSELYPTVLRQTGMGISNIWARVGSMIAPLVKITGELQPFIPNVIFGTMTLLGGSAAFFLL-ETLNRP----LPETIEDIQDWYQQTKKTKQE 520
BLAST of slc22a-6 vs. Ensembl Mouse
Match: Slc22a12 (solute carrier family 22 (organic anion/cation transporter), member 12 [Source:MGI Symbol;Acc:MGI:1195269]) HSP 1 Score: 112.849 bits (281), Expect = 1.105e-25 Identity = 118/478 (24.69%), Postives = 206/478 (43.10%), Query Frame = 1
Query: 382 PKNQTNQVFTEHRNQFKAI-NNETGFLIIDSSRCRLTNISSICSEIFVKKYPM-TSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQIDKYI--EIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVS---RSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQME-------WVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEKNFVE 1773
P Q +Q + Q++ +N T D++ + C + +V + STI + + L C AL A S+F+ GI +G+ G SD FGR SY ++SV T AA P + L+ L R AV+ ++ + + +E +LG+ G +L +A+ +R LQLA ++ ++ ++ ES RWL+ K + + + +A NR+ + + + EEE R + S+ + + ++ +F+ F++Y L + IF L+ AL +V ++ + L RLGR +S L + L I S IL + G ++ + L ++ + G F + I+ E FPTVIR T+V + AR M+ + W+ + V+P++ A+ LLPET P D + +K V+
Sbjct: 81 PDQQPHQCLRFRQPQWQLTESNATATNWSDAA-------TEPCEDGWVYDHSTFRSTIVTTWDLVCNSQALRPMAQSIFLAGILVGAAVCGHASDRFGRRRVLTWSYLLVSVSGTAAAFMPTFPLYCLFRFLLASAVAGVMMNTASLLMEWTSAQGSPLVMTLNALGFSFGQVLTGSVAYGVRSWRMLQLAVSAPFFLFFVYSWWLPESARWLITVGKLDQGLQELQRVAAVNRRKAEGDTLTMEVLRSAMEEEPSRDKAG-ASLGTLLHTPGLRHRTIISMLCWFAFGFTFYGLALDLQALGSNIF---LLQALIGIVDFPVKTGSLLLISRLGRRLCQVSF-LVLPGLCILSNIL--VPHGMGVLRSALAVLGLGCLGGAFTCITIFSSELFPTVIRMTAVGLCQVAARGGAMLGPLVRLLGVYGSWMPLLVYGVVPVLSGLAAL--------LLPETKNLPLPDTIQDIQKQSVK 536
BLAST of slc22a-6 vs. UniProt/SwissProt
Match: sp|Q9VCA2|ORCT_DROME (Organic cation transporter protein OS=Drosophila melanogaster OX=7227 GN=Orct PE=1 SV=1) HSP 1 Score: 134.035 bits (336), Expect = 7.560e-32 Identity = 127/523 (24.28%), Postives = 229/523 (43.79%), Query Frame = 1
Query: 274 FQYFILMFIFISQFNTAINILMPIFINNYQDVYCVLP-KNQTNQVFTEHRNQFKAINNET-GFLIID-------SSRCRLTNISSICSEIFVKKYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVT----ENQIDKYIEIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEKNFVEWRQPWRKSSK 1803
+Q I + + A + L +F+ D C LP +N + + H NE + +D S R +N + CS + ++ +++ L C LS+ + S+FMLG+ LGS+ G SD GR S + +F +AAV+P Y + + R+ G S F+ +ALE+V S R G + + +G++L A+FI D LQ+A + L + + ES RWLL + +A ++ AK N+ V E +D+ E +++ + + ++ ++ +Y + L+++F +F S YY ++ + +IS + ++ +F R GR +IL + +A+I ++ N + MI +++G ++I+ E FPTV+R + S ARV G++A ++ + EI LP+I + LLPET +P + + E NF + P + +
Sbjct: 16 YQKRIYYLLCLPAIVCAFHKLAGVFLLAKPDFRCALPYENGSIYELSPHLWNLSYPENERCSYYDVDYTEEYLNGSIPRSSNETKTCSSYVYDRSKYLNSAVTEWNLVCSRSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVLQLIFGVLAAVAPEYFSYTISRMIVGATTSGVFLVAYVIALEMVGSSYRLFAGVAMQMFFSVGFMLTAGFAYFIHDWRWLQIAITLPGLLFLCYYWIIPESARWLLMKGRKDEAFVIIEKAAKENKVEVPNEIYEQLVDEVAEKKKQDEMAASQPAATVFDLLRYPNLRRKTLLIFFDWFVNSGVYYGLSWNTNNLGGNQLVNFMISGAVEIPGYTLLLFTLNRWGRRSILCGTMMVAGISLLATI---FVPSDMNWLIVACAMIGKLAITSSYGTIYIFSAEQFPTVVRNVGLGASSMVARVGGILAPYLKLLGEIW-RPLPLIICGALSLTAGLLSLLLPETLNKPMPETIEDGE-NFGKKPAPQETAEE 533
BLAST of slc22a-6 vs. UniProt/SwissProt
Match: sp|Q95R48|OCTL_DROME (Organic cation transporter-like protein OS=Drosophila melanogaster OX=7227 GN=Orct2 PE=2 SV=2) HSP 1 Score: 131.724 bits (330), Expect = 5.309e-31 Identity = 133/533 (24.95%), Postives = 235/533 (44.09%), Query Frame = 1
Query: 235 SEKIYQLVGGNSYFQYFILMFIFISQFNTAINILMPIFINNYQDVYCVLP-KNQTNQVFTEHRNQFKAINNET-GFLIID-------SSRCRLTNISSICSEIFVKKYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFY---KESFRWLLATXXXXXXXXVMMHIAKFNRKSVT-----------ENQIDKYIEIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEI-APNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEK 1761
E I L G +Q I I ++ A + L +F+ D C LP +N ++ H NE + +D S R +N + CS + ++ +++ L C +++ + S+FMLG+ LGS+ G SD +GR S + +F +A V+P Y + RL G S F+ +A+E+V +R G + + + +G++L + A+F+ D LQ+A ++ LIF F+Y ES RWLL + A M A+FN+ ++ EN +K + E++ L S+ ++F Y + L+++ + S YY +S + + +IS + + + R GR +IL + +A++I+ + +L +AI+ S +G ++I+ E FPTV+R ++ S AR+SGM+A + ++ I P L I G + G LLPET +P + ++ E+
Sbjct: 4 DEAIIHL-GDFGRYQKIIYFLICLTSIPVAFHKLAGVFLLAKPDFRCALPFENGSSYDLPTHLWNLSYPENERCSYYDVDYTEEYLNGSIPRSSNETKTCSSYVYDRSKYLNSAVTEWNLVCGRDFMAATSDSLFMLGVLLGSIVFGQLSDKYGRKPILFASLVIQVLFGVLAGVAPEYFTYTFARLMVGATTSGVFLVAYVVAMEMVGPDKRLYAGIFVMMFFSVGFMLTAVFAYFVHDWRWLQIA---LTLPGLIFMFYYWIIPESARWLLLKGRKDCAIANMQKAARFNKVEISDEALSELLDEGENSEEKAKQKLEDQELDE-GPPPSVWDLFCYPNLRRKTLLIFLDWLVTSGVYYGLSWNTSNLGGNVLLNFVISGAVEIPAYIFLLLTLNRWGRRSILCGCLVMAGLSLLATVIIPQRMHTLIVACAMLGKLAITAS---YGTVYIFSAEQFPTVVRNVALGAASMVARISGMMAPFLNFLATIWKPLPLLICGSLTLVAGL--LSLLLPETHNKPMLETIADGER 526
BLAST of slc22a-6 vs. UniProt/SwissProt
Match: sp|Q8VC69|S22A6_MOUSE (Solute carrier family 22 member 6 OS=Mus musculus OX=10090 GN=Slc22a6 PE=1 SV=1) HSP 1 Score: 130.954 bits (328), Expect = 6.809e-31 Identity = 109/423 (25.77%), Postives = 199/423 (47.04%), Query Frame = 1
Query: 487 TNISSICSEIFV-KKYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQIDKYIEIFE---EERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTI-LLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSD 1740
T ++ C + +V STI +++ L C + A A S+FM+G+ LG++ G +D GR L+Y +V T AA +P YT++ + RL +G +++ ++ + +E + I R G Y +G LL +A+ + LQLA +V+ I+ +F+ ES RW ++ + + + +A+ N K E IE+ + ++ L + S E+ + + L L ++F+ SF+YY ++ ++ +I L ++ + + +GR L SL L + + II + G II T L ++ ++F +++Y GE +PT+IR T + +GS ARV +++ + E P++ I + + S T LLPET +P D
Sbjct: 93 TGVTEPCLDGWVYDNSTFPSTIVTEWNLVCSHRAFRQLAQSLFMVGVLLGAMMFGYLADRLGRRKVLILNYLQTAVSGTCAAYAPNYTVYCIFRLLSGMSLASIAINCMTLNMEWMPIHTRAYVGTLIGYVYSLGQFLLAGIAYAVPHWRHLQLAVSVPFFVAFIYSWFFIESARWYSSSGRLDLTLRALQRVARINGKQ--EEGAKLSIEVLQTSLQKELTLNKGQASAMELLRCPTLRRLFLCLSMLWFATSFAYYGLVMDLQGFGVSMYLIQVIFGAVDLPAKFVCFLVINSMGRRPAQLASLLLAGICILVNGIIPR----GHTIIRTSLAVLGKGCLASSFNCIFLYTGELYPTMIRQTGLGMGSTMARVGSIVSPLISMTAEFYPSIPLFIFGAVPVAASAVT-ALLPETLGQPLPD 508
BLAST of slc22a-6 vs. UniProt/SwissProt
Match: sp|Q91WU2|S22A7_MOUSE (Solute carrier family 22 member 7 OS=Mus musculus OX=10090 GN=Slc22a7 PE=1 SV=1) HSP 1 Score: 127.487 bits (319), Expect = 9.745e-30 Identity = 129/532 (24.25%), Postives = 233/532 (43.80%), Query Frame = 1
Query: 238 EKIYQLVGGNSYFQYFILMFIFISQFNTAINILMPIFINNYQDVYCVLPKNQTN----------QVFTEHRNQF---------KAINNET-GFLIIDSSRCRLTNISSICSEIF-VKKYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQIDKYI--EIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEKN 1764
E++ VGG FQ L+ + + +F ++ L+PIF+ +C LP N + E F +A+ N T G + +S ++ CS+ + + +STI +++ L CE L+ ++ F +G+ LG+V G SD FGR ++Y ++A S Y + R+ TG A++ + + LE +++ RT G + + G LLL L+ + IR L LA +I ++ ES RWLL + ++AKK + AK N + ++E+ + + ++ ER VS R S ++F+ + L ++F +FSYY L +S + ++ L+ + S+ FL + +GR + L F S++ + T L++I + S F +++ E +PTV+R T + + R+ +A + + + +LP + F + CT LLPET K + + E+
Sbjct: 4 EELLHKVGGFGPFQLRNLVLLALPRFLLPMHFLLPIFMAAVPAHHCALPDAPANLSHQDLWLKTHLPRETDGSFSSCLRFAYPQALPNVTLGTEVYNSGEPEGEPLTVPCSQGWEYDRSEFSSTIATEWDLVCEQRGLNKVTSTCFFIGVLLGAVVYGYLSDRFGRRRLLLVAYVSTLALGLMSAASVNYIMFVTTRMLTGSALAGFTIIVLPLELEWLDVEHRTVAGVISTTFWTGGVLLLTLVGYLIRSWRWLLLAATLPCVPGIISIWWVPESARWLLTQGRVEEAKKYLSICAKLNGRPISEDSLSQEALNKVITMER---VSQRPSYLDLFRTSQLRHVSLCCMMMWFGVNFSYYGLTLDASGLGLTVYQTQLLFGAVEVPSKITVFFLVRLVGRRLTEAGMLLATALTFGISLL---VSSDTKSWITALVVIGKAFSEAAFTTAYLFTSELYPTVLRQTGMGFTALIGRLGASLAPLVV-LLDGVWLLLPKLAYGGISFLAACTVLLLPETKKAQLPETIQDVERK 528
BLAST of slc22a-6 vs. UniProt/SwissProt
Match: sp|O57379|S22A6_PSEAM (Solute carrier family 22 member 6 OS=Pseudopleuronectes americanus OX=8265 GN=SLC22A6 PE=1 SV=1) HSP 1 Score: 124.79 bits (312), Expect = 8.796e-29 Identity = 105/410 (25.61%), Postives = 192/410 (46.83%), Query Frame = 1
Query: 538 TSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQID-KYIEIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEKN 1764
+STI S++ L C+ H+ +++M G+ +G++ G SD +GR I +S +++V T AA S ++L + R G A+S ++ + +E + RT G Y +G L+LVLLA+FIRD L LA YV + +++ ES RWL + + + A K + +A+FN + ++D K + ++ + SI ++F + L L ++ S SF+YY + K +I+ +I + ++ + + +GR ++ + + ++++ Y K I T L ++ +F ++Y GE FPT+IR + S AR+ M+A + + P + +I + L F LPET P D + E++
Sbjct: 129 SSTIISEWHLVCDMHSFKQMGQTIYMGGVLVGALLFGGLSDRYGRRILLLISNLLMAVSGTCAAFSSSFSLFCVFRFGCGLALSGLGLNTFSLIVEWIPTRIRTAVGTTTGYCYTLGQLILVLLAYFIRDWRWLTLAVSLPFYVFFLIAWWFHESSRWLALSNRTEHALKNLKSVARFNGRHEEAEKLDIKMLHESMKKEMSCTQGSYSILDLFNTPAMRKRTLCLSAVWLSTSFAYYGLAMDLDKFGVDIYLIQVIFGAVDIPAKVVVVVSMSLIGRRRSQCAVLVVAGITILLNLLVPY---DKQTIRTCLAVLGKGCLAASFNCCYLYSGELFPTIIRQNGMGWVSMMARIGAMVAPMVLLTRDYIPWLPGLIYGGAPILSGLAAIF-LPETLGYPLPDTIQDVEES 534
BLAST of slc22a-6 vs. TrEMBL
Match: A0A0H3YJ98 (Slc22a-6 OS=Schmidtea mediterranea OX=79327 GN=slc22a-6 PE=2 SV=1) HSP 1 Score: 1046.96 bits (2706), Expect = 0.000e+0 Identity = 533/533 (100.00%), Postives = 533/533 (100.00%), Query Frame = 1
Query: 232 MSEKIYQLVGGNSYFQYFILMFIFISQFNTAINILMPIFINNYQDVYCVLPKNQTNQVFTEHRNQFKAINNETGFLIIDSSRCRLTNISSICSEIFVKKYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQIDKYIEIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEKNFVEWRQPWRKSSKKIIDTEIKV 1830
MSEKIYQLVGGNSYFQYFILMFIFISQFNTAINILMPIFINNYQDVYCVLPKNQTNQVFTEHRNQFKAINNETGFLIIDSSRCRLTNISSICSEIFVKKYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATKKYKKAKKVMMHIAKFNRKSVTENQIDKYIEIFEEERLRSVSHRVSIKEVFKYKVVLVNLLVLWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEKNFVEWRQPWRKSSKKIIDTEIKV
Sbjct: 1 MSEKIYQLVGGNSYFQYFILMFIFISQFNTAINILMPIFINNYQDVYCVLPKNQTNQVFTEHRNQFKAINNETGFLIIDSSRCRLTNISSICSEIFVKKYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATKKYKKAKKVMMHIAKFNRKSVTENQIDKYIEIFEEERLRSVSHRVSIKEVFKYKVVLVNLLVLWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEKNFVEWRQPWRKSSKKIIDTEIKV 533
BLAST of slc22a-6 vs. TrEMBL
Match: A0A1D2NMQ1 (Organic cation transporter protein OS=Orchesella cincta OX=48709 GN=Ocin01_00454 PE=4 SV=1) HSP 1 Score: 158.688 bits (400), Expect = 2.195e-37 Identity = 140/547 (25.59%), Postives = 247/547 (45.16%), Query Frame = 1
Query: 199 EIKLKITLLKQMSEK-----IYQLVGGNSYFQYFILMFIFISQFNTAINILMPIFINNYQDVYCVLP-KNQTNQVFTEHRNQFKAINNETGFLIIDSSR---CRLTNISSICSEIFVKKYPMTSTI-----------------RSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQIDKYIEIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEK 1761
E+KLK+ ++ K ++ ++G +Q + + + + A++ L +F+ D C LP + ++ V+ E + I F + CR + E F P T+T R + L C+ + + A ++FM+GI +GS+ G SD +GR LS + VF +A ++P Y + R+ G + S F+ +A+E+V S+RT G L + GYL+ +LA+ I D LQ+A V L + +F ES RWLLA + +A ++ +AK N+ +++ D+ +E +E + S+ ++FKYK + + L ++ +F S YY L +S + + I+ + + +F R GR +L L A F+++ L N + MI ++G ++I+ E+FPTV+R + V S CARV G++A+ + + ++ LP++ A F S L+PETF + D + EK
Sbjct: 74 EVKLKVEPREEDENKMKFDSLFPIIGDFGRYQKRVYLLLCLPAICCAMHKLAWVFLGAKLDHRCRLPIETESTAVYNELP---QGIPFNMTFPFEKDGKVESCRRLAVDFTDQEYFNAGVPSTNTTKCGDEYVFDYSKYKTSARVDYNLLCDNQFMYTNAQTLFMVGILIGSILFGDLSDRYGRRPIFFLSLVLQVVFGILAGLAPEYWTFVIARMIVGSSTSGIFLVGFVIAMEMVGPSKRTFVGVVCQLFFTAGYLVTAVLAYLITDWKMLQIALSVPGLVFLSYYWFLPESVRWLLARGRKDEANAILKDVAKENKVTLS----DEVLESLSDEPKTNPMQSASVLDLFKYKRMSLRSLNIFLCWFVNSGVYYGLSLNTSNLGGNDYINFAIAGAVEVPAYLFLLFSLNRFGRKVVLCGCMLAGGA-FMSACALVPESEEWNWVLIAFAMIGKMCITASYGVIYIFSAESFPTVVRNSGVGASSMCARVGGIVANNLLLLGDLIWKPLPLLIFGAASFISGLLSLLIPETFGKRLPDTMEDGEK 612
BLAST of slc22a-6 vs. TrEMBL
Match: A0A3B3BBV4 (MFS domain-containing protein OS=Oryzias melastigma OX=30732 PE=4 SV=1) HSP 1 Score: 154.066 bits (388), Expect = 3.025e-36 Identity = 108/406 (26.60%), Postives = 209/406 (51.48%), Query Frame = 1
Query: 541 STIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQIDKYIEIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAE 1758
ST +++ L CE ++++ +S++M G+ +G++ G +D +GR I +S + +VF T AA +P + ++ R G ++S ++ + E + QR G + GY+LL LA+ IRD KLQLA ++ +I+ + +S RWL+A + ++A +V++ A+ N K ++++ I+ ++++ ++ + + S ++ + + + L++++++F YY L S I+ +I L + +R+I +F R +++ L L +G +A + I ++ I+ T+L MI + +++Y E FPTVIR + IGS CAR G++A M + I+P+ ++ + GS T LLPET +P D + E
Sbjct: 109 STTVTEWDLVCENASMNNLGSSIYMFGLLVGALVFGNLADKYGRRIIILISLAIQAVFGTAAAFAPNFYVYTALRFMVGTSISGVIMNAFVLGTEWTGLKQRMLAGIITDYFFGFGYILLAGLAYLIRDWRKLQLAISAPGFLFIIYIWVLPKSARWLMANDRVEEALEVIVKAAQMNGKPISKD-IEMCQQVYKADQTAVLKKKHSFVDLVRTPTMRKHSLIVFYLWFVNVLVYYGLSLNISDFGMNIYLTQMIFGLVEMPARTITLFTLNRSRKISQLAFLAVGGSACLLTIFIPSRLF----IVKTILAMIGKFGITASLSIIYVYSAEVFPTVIRQNGIGIGSMCARTGGVLAPMMYLLRSISPHAPMVLSGLCPLVGSALT-LLLPETANKPLPDTIEDVE 508
BLAST of slc22a-6 vs. TrEMBL
Match: A0A437C1E7 (MFS domain-containing protein OS=Oryzias javanicus OX=123683 GN=OJAV_G00233380 PE=4 SV=1) HSP 1 Score: 152.525 bits (384), Expect = 9.031e-36 Identity = 108/405 (26.67%), Postives = 207/405 (51.11%), Query Frame = 1
Query: 544 TIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQIDKYIEIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAE 1758
T +++ L CE ++++ +S++M G+ +G++ G +D +GR I +S + +VF T AA +P + ++ R G ++S ++ + E + QR G + GY+LL LA+ IRD KLQLA ++ +I+ + +S RWL+A + ++A +V++ A+ N K ++++ I+ ++++ ++ + + S ++ + + L++++++F YY L S I+ LI L + +R+I +F R +++ L L +G +A + I ++ I+ T+L MI + +++Y E FPTVIR + IGS CAR G++A M + I+P+ ++ + GS T LLPET +P D + E
Sbjct: 110 TTVTEWDLVCENASMNNLGSSVYMFGLLVGALVFGNLADKYGRRIIILISLAIQAVFGTAAAFAPNFYVYTALRFMVGTSISGVIMNAFVLGTEWTGLKQRMLAGIITDYFFGFGYILLAGLAYLIRDWRKLQLAISAPGFLFIIYIWVLPKSARWLMANDRVEEALEVIVKAAQMNGKPISKD-IEMCQQVYKADQNTVLKKKHSFIDLVRTPTMRKQSLIVFYLWFVNVLVYYGLSLNISDFGMNIYLTQLIFGLVEMPARTITLFTLNRSRKISQLAFLAVGGSACLLTIFIPSRLF----IVKTILAMIGKFGITASLSIIYVYSAEVFPTVIRQNGIGIGSMCARTGGVLAPMMYLLRSISPHAPMVLSGLCPLVGSALT-LLLPETANKPLPDTIEDVE 508
BLAST of slc22a-6 vs. TrEMBL
Match: B4LVT8 (MFS domain-containing protein OS=Drosophila virilis OX=7244 GN=Dvir\GJ24208 PE=4 SV=1) HSP 1 Score: 151.754 bits (382), Expect = 2.291e-35 Identity = 133/532 (25.00%), Postives = 234/532 (43.98%), Query Frame = 1
Query: 235 SEKIYQLVGGNSYFQYFILMFIFISQFNTAINILMPIFINNYQDVYCVLPKNQTNQVFTEHRNQFKAINNETGFLIIDS-----------SRCRLTNISSICSEIFVKKYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVT----ENQIDKYIEIFEEERLR--------SVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEK 1761
E I QL G +Q I I ++ A + L +F+ D C LP + E Q K E + DS S R +N + CS + ++ ++F L C L++ + SMFMLG+ LGS+ G SD +GR S + +F VA V+P Y + L R+ G S F+ +A+E+V ++R G + + + IGY+L A+FI D LQ+ + + + + ES RWLL+ + A +V+ A+FNR +T E +D+ +E++L + S+ ++ Y + LV++F + C+ YY ++ + + +IS + + + R GR +IL L + +II+ + ++ +AI+ S +G ++++ E FPTV+R + S +R++GM+A + + + P LP++ + C LLPET RP+ + ++ E+
Sbjct: 4 DEVIVQL-GDFGRYQMIIYTLICLTSIPVAFHKLAGVFLLAKPDFRCALPTDLDESASYELPAQLK----ELAYPATDSCAYYELAYANGSYYRTSNETHSCSRYIYDQSRYQNSAVTEFDLVCGRGFLAATSDSMFMLGVLLGSIIFGQLSDKYGRKPIFFASLVIQVIFGVVAGVAPEYFTYTLARIVVGSTTSGVFLVAYVIAMEMVGPAKRLYAGIFVMMFFSIGYMLTAAFAYFIHDWRWLQIGLTLPGLLFMCYYWIIPESVRWLLSKGRKADAIQVIQKAARFNRVDITTEALEALLDEGASCQQEQKLDQDEDDDGCEETRPPSVWDLLHYPNLRRKTLVIFFDWLVCTGVYYGLSWSTNNLGGNVLLNFVISGAVEIPAYCFLLLTLNRWGRRSILCGCMLVAGVSLLLTIIVPQDMHWLTVTCAMVGKLAITGS---YGTIYLFSSEQFPTVVRTVGMGAASMVSRLTGMLAPYLNALATLWPP-LPLVIYGALSLAAGCLSLLLPETHNRPTLETIADGER 526
BLAST of slc22a-6 vs. Ensembl Cavefish
Match: si:dkey-119m7.4 (solute carrier family 22 member 13-like [Source:NCBI gene;Acc:103028301]) HSP 1 Score: 150.214 bits (378), Expect = 1.927e-38 Identity = 128/511 (25.05%), Postives = 245/511 (47.95%), Query Frame = 1
Query: 238 EKIYQLVGGNSYFQYFILMFIFISQFNTAINILMPIFINNYQDVYCVLPKNQTNQV-FTEHRNQFKAINNETGFLIIDSSRCRLTNISSICSEIF-VKKYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGR--IIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQIDKYIEIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAE 1758
+++ +GG FQ + ++I + Q A ++L+ +F C K T+ FT ++ +A + ++ T+ ++ C + + K ST+ ++F L C+ L++ +S++M G+ +G+V GV +D +GR II GL+ + ++F AA +P + ++ L R G VS ++ + E R G + +GY+LL +A+ IRD KLQLA ++ + + + +S RWL+A K ++A ++ A N+K + N ++ + + E+ H ++ ++ + + L+L++++F YY L S I+ LI L + +R+I +F R R++ L L +G +A ++ +I ++ T+L M+ + +++Y E FPTV+R + +GS CAR G+IA + + I+P+ ++ + G+L T LLPET +P D + E
Sbjct: 4 DEVLARIGGFGRFQKILYVWICLPQIFLAFHMLVSVFTGAVPPHLCRDTKTHTHNFNFTLSQSASEACGST------HTNSSLSTHTTTACRDGWEFSKDVFLSTVVTEFDLVCDSATLNNIGSSIYMFGLLVGAVVFGVLADRYGRRIIILVGLA--LQAMFGVGAAFAPNFFIYVLLRFVVGTTVSGIIMNAFVLGTEWTGPKHRMLAGIITDYFFGVGYILLAGVAYLIRDWRKLQLAISAPGFIFIFYIWVLPKSARWLMANGKQEEAMDLICKAALINKKPLKGNDMEFQLNNCKVEQKLQRKH--TVVDLVRTPQMRKQSLILFYLWFVNVLVYYGLSLNVSDFGMNIYLTQLIFGLVEMPARTITLFTLNRSRRISQLSFLAVG----GLACLLTIFIPQNLPVVRTILAMLGKFGITASLSIVYVYSAEVFPTVVRQNGIGMGSMCARAGGVIAPIIYLLRRISPHAPMVVFGLCPLVGALLT-ILLPETAHKPLPDTIEDVE 499
BLAST of slc22a-6 vs. Ensembl Cavefish
Match: oatx (solute carrier family 22 member 6-like [Source:NCBI gene;Acc:103046614]) HSP 1 Score: 139.043 bits (349), Expect = 2.282e-34 Identity = 129/551 (23.41%), Postives = 244/551 (44.28%), Query Frame = 1
Query: 256 VGGNSYFQYFILMFIFISQFNTAINILMPIFINNYQDVYCVLPKNQTNQVFTEHRNQFKAINNETGFLIIDSS---RC-RLTNI--------------------SSICSEIFV-KKYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFN-RKSVTENQIDKYIEIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEKNFVEWRQPWRKSSKKIIDTEIKV 1830
VGG FQ+ + + I A L+ F YC +P N T T++ ++ + F+ ++ S RC R T + C + + ++ STI S++ L C+ +L + +++M G+ G++ G SD FGR SYF +++ + A+SP Y + R TG +VS ++ + + +E + RT G S + G +LL +A+ ++D L +A C ++ ++ ++Y ES RWL+ + +A K + H+A+ N R +T+ + ++ + + S + ++ + V+ + + ++FS SF+YY + K I+ +I ++ + + + GR S L A+ A+I ++ ++ T L ++ + ++F +++Y GE +PTVIR T + S ARV M A + + E+ P I+ A+ + FLLPET P D + E+ +W Q R K++ + +
Sbjct: 10 VGGFGRFQWIHVALLSIPSLLMASQNLLNNFTAGVPGHYCKIP-NITALAETQNLSEPSSAEILPAFIPLEGSKLSRCSRYTTAQWHLLHQNASHAESNTTDAETETCQDGWTYERTEFISTIVSEWDLVCKLRSLKQMSQTIYMGGVLAGAIIFGGLSDRFGRKALLIWSYFQLALLGSFTALSPSYLAYCTFRFLTGMSVSGVILNAASLKVEWIPTENRTLVGTISSFFFTFGQVLLAGVAYSLKDWRYLHVAVCSPFFIFFLYSWWYSESARWLVLNGRSDEALKQLHHVARINGRPEMTKKITLEVLQSHMRKEIESSKTVYTAYDLLRTPVMRKISMCIVAVWFSTSFAYYGLAMDLQKFGVNIYVMQIIFGAVDFPAKLVALGMLSFFGRRMTQASCLLASGAVIFANI---FVPKDMQMVRTTLAVLGKGFTSSSFTCVYLYTGELYPTVIRQTGMGFASMMARVGSMAAPAVLILDELFPAFPSIVYGGSAVVAGIIA-FLLPETLDVPLPDTVEDVEE---KWGQKGRSFQKQVASESVAL 552
BLAST of slc22a-6 vs. Ensembl Cavefish
Match: slc22a6l (solute carrier family 22 member 6-like [Source:NCBI gene;Acc:103025663]) HSP 1 Score: 136.732 bits (343), Expect = 1.253e-33 Identity = 117/430 (27.21%), Postives = 209/430 (48.60%), Query Frame = 1
Query: 535 MTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQIDKYIEIFEEERLRSV-----SHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPII-GMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEKNFVEWRQPWRKSSKK 1806
M+STI +++ + CE +L +++M G+ +G++ G SD FGR +S+ M++V T A+ + + L L R F G A+S +++ + +E + RT G + Y +G LLL +A+ IRD L LA YVS ++ +++ ES RWL+ + + ++A K + +A+FN + ++I+ IE+ ++ + + SH ++ + + + L ++FS SF+YY L K +I+ +I + S+ I +LGR S + + ++++ Y + + T L +I G +F +++ GE FPTV+R + + S ARV M+A + + P + +I G T + G F LPET P D + A W++P SSKK
Sbjct: 125 MSSTIITEWDMVCESRSLKPMGQTIYMAGVFVGAMVFGGLSDRFGRRNLLLISHLMMAVGGTCASFATSFYLFCLFRFFCGMALSGLVLNSFSLVVEWIPTRIRTVVGTFTGYCYTLGQLLLAAVAYTIRDWRWLTLAVSVPFYVSFLYSWWFVESARWLVLSNRPEQAVKNLKAVARFNGRREEGDKIN--IEVLQQSMKKEMACSQKSHNA--LDLIRTPTMRTITICLSAVWFSTSFAYYGIALDLQKFGVDIYLIQVIFGAVDIPSKVIITLSMSKLGRRVSQCSALIMAGICILVNLLVPY---EQQTLRTSLAVIGKGCLGASFNCCYLFSGELFPTVVRQSGMGWVSMMARVGAMVAPMVLLTGDSLPWLPGVIYGGTPILCGMFAYF--LPETLSAPLPDTIQDAVDRGFRWKKP---SSKK 542
BLAST of slc22a-6 vs. Ensembl Cavefish
Match: si:dkey-166k12.1 (organic cation transporter protein-like [Source:NCBI gene;Acc:103028750]) HSP 1 Score: 128.257 bits (321), Expect = 5.895e-31 Identity = 128/524 (24.43%), Postives = 233/524 (44.47%), Query Frame = 1
Query: 238 EKIYQLVGGNSYFQYFILMFIFISQFNTAINILMPIFINNYQDVYCVLPKNQTNQVFTEHRNQFKAI-------NNETGFLIIDSSRCRLTNIS-----SICSEIFVKKYPM-TSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKS-VTENQIDKYIEIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFL--CKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEK 1761
E++ GG FQ + ++I + Q A ++++ +F C ++ + + H NQ A+ N+ G + C + S C +V + ST +++ L C +L+S +S++MLG+ +G+V G +D +GR LS + +VF AA +P + ++ + R G +S ++ + E +R G + + +GY+LL +A+ IRD KLQLA ++ + + + S RWLL + ++A ++ A N +S T Q+D + + E SV+ V E+ K L+L++I+F YY LG S + +++ + L + +RS+ + + C R ++ L + G L +A + I T L M +F ++IY E FPTV+R T + + S AR+ G++A + + + P V+P++ LPET +P D + AE+
Sbjct: 4 EQLLAAAGGFGRFQKTLYVWICLPQVQLAFHMMVSVFTGATPPHRC-----RSARPGSPHLNQSHAVVLELRLANSSAGISAGHADACSAGSAENRSARSACESGWVYSQDVFESTTVTEWDLVCGRASLNSICSSIYMLGLLVGAVVFGAMADRYGRRFALLLSLALQTVFGVAAAFAPNFLVYVILRFLIGTTISGIIINAFVLGTEWTSTKRRMLAGIFTDYFFGLGYMLLAGIAYLIRDWRKLQLAISAPGFLFIFYIWVLPHSARWLLVNDRKEEAIVLLRKAAMVNGRSFPTTVQLD-WCDETEGRSQHSVADLVRTPEMRKRA------LILYYIWFVNVLVYYGLSLGVSGLGTDLYFTQFMFGLVEVPARSLVLLVLPCSRRIPLSAFLFIGGGACLLMLA------VPADNPNIQTALAMTGKFGITASFAIIYIYSAELFPTVLRQTGIGVSSMFARMGGVLAPMINLLGQHNP-VVPVLIFGSTPLLGAALALALPETANKPLPDTIQDAER 508
BLAST of slc22a-6 vs. Ensembl Cavefish
Match: si:dkey-166k12.1 (organic cation transporter protein-like [Source:NCBI gene;Acc:103028750]) HSP 1 Score: 124.405 bits (311), Expect = 1.138e-29 Identity = 127/514 (24.71%), Postives = 230/514 (44.75%), Query Frame = 1
Query: 238 EKIYQLVGGNSYFQYFILMFIFISQFNTAINILMPIFINNYQDVYC--VLPKNQTNQVFTEHRNQFKAINNETGFLIIDSSRCRLTNISSICSEIFVKKYPM-TSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKS-VTENQIDKYIEIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFL--CKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEK 1761
E++ GG FQ + ++I + Q A ++++ +F C + N + + H + A + E S+R S C +V + ST +++ L C +L+S +S++MLG+ +G+V G +D +GR LS + +VF AA +P + ++ + R G +S ++ + E +R G + + +GY+LL +A+ IRD KLQLA ++ + + + S RWLL + ++A ++ A N +S T Q+D + + E SV+ V E+ K L+L++I+F YY LG S + +++ + L + +RS+ + + C R ++ L + G L +A + I T L M +F ++IY E FPTV+R T + + S AR+ G++A + + + P V+P++ LPET +P D + AE+
Sbjct: 4 EQLLAAAGGFGRFQKTLYVWICLPQVQLAFHMMVSVFTGATPPHRCRSLRLANSSAGISAGHADACSAGSAEN-----RSAR-------SACESGWVYSQDVFESTTVTEWDLVCGRASLNSICSSIYMLGLLVGAVVFGAMADRYGRRFALLLSLALQTVFGVAAAFAPNFLVYVILRFLIGTTISGIIINAFVLGTEWTSTKRRMLAGIFTDYFFGLGYMLLAGIAYLIRDWRKLQLAISAPGFLFIFYIWVLPHSARWLLVNDRKEEAIVLLRKAAMVNGRSFPTTVQLD-WCDETEGRSQHSVADLVRTPEMRKRA------LILYYIWFVNVLVYYGLSLGVSGLGTDLYFTQFMFGLVEVPARSLVLLVLPCSRRIPLSAFLFIGGGACLLMLA------VPADNPNIQTALAMTGKFGITASFAIIYIYSAELFPTVLRQTGIGVSSMFARMGGVLAPMINLLGQHNP-VVPVLIFGSTPLLGAALALALPETANKPLPDTIQDAER 491
BLAST of slc22a-6 vs. Ensembl Sea Lamprey
Match: oct2 (organic cation transporter 2 [Source:ZFIN;Acc:ZDB-GENE-080204-92]) HSP 1 Score: 94.7449 bits (234), Expect = 1.095e-20 Identity = 97/408 (23.77%), Postives = 186/408 (45.59%), Query Frame = 1
Query: 544 TIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQIDKYIEIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALF-IASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLP-IIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEK 1761
T+ S+F L CE L + ++ +G+ +G++ G SD +GR +S M ++F + A +P Y R G S+ + A E V QR + + G ++L +A+++R LQLA + V + + ES RWL++ + ++A V+ IA N + +++N I K E E R + SI ++ + + +VL +F Y + + I D+++ A L+ L + + + L R+GR + + + G++ L +A+ ++ + G NI L + ++++ + + + E +PT +R ++S S+ + + G++A + + LP +I T+A+ G LLPET P + AE
Sbjct: 141 TLVSEFDLVCENAWLLDLSQALLNVGLLVGAILMGYVSDRYGRRWSLMVSIVMQTIFGVLVAFAPNYAAFVCMRTLQGIFNMGSWTTVFVTATEFVGSGQRRVVHMVLQMFFSFGVIMLSGIAYYLRTWRYLQLALTLPNVVLFSYYWLLPESPRWLISQNRKEQAFGVLKKIASVNGRELSDN-IRKNFE--EVTRADEKAGNPSIADLMRSAKIRKYTVVLMIYWFVVGVVYQGLAMSTGNIGDDVYLAFLMGGLAEIPGALMVIALIDRVGR-RLPMCVAPGLSGLACLATALVPHDIGWLNITLVTLGRLGLTMA---YEMVTLVNNELYPTHLRNMAMSTCSSLSGIGGIVAPFVLYRLYTIWRHLPMVIFGTLAIIGGF-VILLLPETNGLPLPETTEDAEN 540
BLAST of slc22a-6 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007122.1 (pep scaffold:Pmarinus_7.0:GL476962:153150:164773:-1 gene:ENSPMAG00000006444.1 transcript:ENSPMAT00000007122.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 81.2629 bits (199), Expect = 1.935e-17 Identity = 62/241 (25.73%), Postives = 112/241 (46.47%), Query Frame = 1
Query: 238 EKIYQLVGGNSYFQYFILMFIFISQFNTAINILMPIFINNYQDVYCVLPKNQTNQVFTEHRNQFKAINNETGFLIIDSSRC--RLTNIS-SICSEIF-VKKYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLA 948
+ + + +GG FQ + +I + + A+++L+ +F +C P V + A + RC RL C+ + + TST+ +++ L C L++ +S+FMLG+ +G+ G +D +GR +S + + F AA +P + ++AL R G A+S ++ +A E I +R G + +GY+LL +A+FIRD +LQLA
Sbjct: 4 DDVLKKIGGFGKFQMILYTWICLPHISIAMHMLVSVFAGATPAHFCRDPPGGHAPVPSATTAPPTA-GESAAANGTERPRCGSRLNESGWQPCATGWDYDRSVFTSTVVTEWDLVCTRSYLNNVGSSIFMLGLMVGAPVLGTMADKYGRKSVILVSMAIQTAFGLGAAFAPNFVMYALARFMVGVAISGVIMNAFVLATEWTGIGERMLAGIATQQAFGVGYMLLAPVAYFIRDWRQLQLA 243
BLAST of slc22a-6 vs. Ensembl Sea Lamprey
Match: SLC22A7 (solute carrier family 22 member 7 [Source:HGNC Symbol;Acc:HGNC:10971]) HSP 1 Score: 82.4185 bits (202), Expect = 2.219e-17 Identity = 71/279 (25.45%), Postives = 121/279 (43.37%), Query Frame = 1
Query: 238 EKIYQLVGGNSYFQYFILMFIFISQFNTAINILMPIFINNYQDVYCVLPKNQTNQVFTEHRNQFKAINNETGFLIIDS---SRCRL-----TNISS----------ICSEIFV-KKYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLL 1017
E+ GG S FQ ++ + + + + ++++ FI+ C LP + T + + + D S C L TN S C + + T T+ +Q+ L CE+ AL+ + ++FM G+ LGS+ G SD +GR SY + +V T AA +P ++ R G ++S V+ +++E ++ RT G + G + L LLA+ +R +LQL Y ++ +F ES RWLL
Sbjct: 4 EEALSAAGGFSRFQLWLTVLLLVPRLVLPWHLMVNNFISATPHHRCRLPDSPTAAPLDNGSGPAETWGGQPPWRDDDEEGLSACSLREAAGTNASESPLRNSSEAVPCPSGWEYDRRQFTETVVTQWDLVCEHKALNHLSLTLFMAGVMLGSLVFGYLSDRYGRRNALLGSYVLNAVTGTAAAWAPSFSSFTAMRFLLGVSLSGIIVNTLSLSVEWLDQGHRTFAGTSGGFAWSTGNMALGLLAYLLRGWQQLQLVVTSPIYFCILTWWFIPESPRWLL 282
BLAST of slc22a-6 vs. Ensembl Sea Lamprey
Match: slc22a6l (solute carrier family 22 member 6, like [Source:NCBI gene;Acc:404609]) HSP 1 Score: 67.781 bits (164), Expect = 1.574e-12 Identity = 76/317 (23.97%), Postives = 132/317 (41.64%), Query Frame = 1
Query: 820 LEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQIDKYIEIFEEERLRSVSHRV-----SIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNV-LPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQ 1752
+E + + RT +G + Y G L+LV LA++IRD LQ + YV + + ES RWL+ Y++A + +A N + Q+ ++ +E R ++ + + + + ++W C ++ + ++ + + + A+ + L R T SL + IAS L I T L ++ +F ++Y GE FPTVIR + + + S ARV GM+A + E P + L + G + GSL F LPET RP + + +
Sbjct: 1 VEWIAMKDRTLYGMLSGVAYTTGQLVLVALAYYIRDWRHLQHSISAAFYVFFLCSWCTPESARWLVMRGHYERALHGLKRVAVINGRKREAAQLTSPLQYLRKELEEDTGPRRFYTMFNLLTIPALRRRTLVMSLVWCDDVFCWYAGFVVIV-TRTCAHTFLLQVIYGAIDYPAKVVGLVVLSLLGRRATQAGSLAVAS----IASFCLLAIPAESGTARTCLAVLGKGALSCSFNCAYLYTGEIFPTVIRQSGLGLCSTMARVGGMLAPLVIMAGESLPALPLSMYGSASLVAGSLVYF--LPETLNRPLPETIEE 310
BLAST of slc22a-6 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002617.1 (pep scaffold:Pmarinus_7.0:GL485729:386:8898:-1 gene:ENSPMAG00000002389.1 transcript:ENSPMAT00000002617.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 57.3806 bits (137), Expect = 6.887e-10 Identity = 48/181 (26.52%), Postives = 82/181 (45.30%), Query Frame = 1
Query: 1225 FSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFL-----CKRLGRVTILLSLQLGVTALFIASII-LKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIAS------QMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRP 1731
F CS YY LG +S ++ +S L L S + +FL C R ++ LS G+ + +A+++ L + G + L + F ++IY E +PT IR ++ + S +R+ G++A + WV P + ++G+ G LC LLPET ++P
Sbjct: 1 FVCSLVYYGLTLGVGDLSRDVHMGLALSGLAELPSYPLSLFLINASWCGRRRGLSGFLSCG-GIACIAVAALVTLSGEHEGCAVARQYLALAGKLCISAAFSIVYIYTSELYPTSIRNVALGLSSTSSRLGGILAPFIPSLREQSWVMPSLPFM--VLGLAGVSAGCLC--LLLPETLRQP 176
BLAST of slc22a-6 vs. Ensembl Nematostella
Match: EDO35192 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM88]) HSP 1 Score: 107.457 bits (267), Expect = 5.987e-25 Identity = 106/434 (24.42%), Postives = 205/434 (47.24%), Query Frame = 1
Query: 556 QFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQIDKYI-EIFEE-ERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNV---LPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEKNFVEWRQP-------WRKSSKKIIDTE 1821
Q+ L C+ L + + +MF++G+ +GS+ G+ SD FGR + +S F++ V S ++ + +L AL R GF+V+ ++ LE+V ++RT G + IG LL + IRD L L + V F + E+ RWL+A A+ ++ A + ++V + + +I+EE +R + R + ++ K + +++ F +F S Y+ F+L + +S +++ L+ ++ + + I FL +++GR S+ L T I ++L +++T + +M + F +++Y E +PTVIR T++ S AR+ G+IA + + ++ P+V LPI+ + + LPET + + + E ++ P WR + + E
Sbjct: 2 QWDLICDRAHLGATSQAMFLVGMLVGSLLSGIMSDAFGRRLCMLISCFIMIVCSAASSFADCLSLFALLRFGVGFSVTGLMLTQYVYVLELVGPTKRTAAGKVTDFFWVIGACATCLLGYLIRDWRILLLVRSLPAVVFFFFWKVFPETARWLVAKGNLVDAQVILEKCA--DGRAVDSRSLQTLLQDIYEEQQRQEKTTRRYTPLDMIKTPKLRRRTIIVCFNWFVVSIIYFGFVLYITSLSGDVYINFLLMSIIDVFNTPISWFLLQKIGRRLTHCSIML--TGGLICVLVLVVPKEYTSVVTGIAIMGKFCDTAA-FSTIYLYTSELYPTVIRNTAMGTASMFARIGGIIAPYIVMLAQL-PSVSITLPIVIFGVCSLAAGVMSLWLPETLRTTMQQTIEETEMTPEDYGIPCCGCLGAWRTEDVIVNNDE 429
BLAST of slc22a-6 vs. Ensembl Nematostella
Match: EDO36696 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHW2]) HSP 1 Score: 105.531 bits (262), Expect = 5.743e-24 Identity = 131/536 (24.44%), Postives = 241/536 (44.96%), Query Frame = 1
Query: 238 EKIYQLVGGNSYFQYFIL---MFIFIS-QFNTAINILM---PIFINNYQDVYCVLPKNQTNQVFTEHRNQFKAINNETGFLIIDSSRCRLTNISSICSEIFVKKYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGR--------IIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIF-PFFYK---ESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQIDKYIEIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSG-----TNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEKNFVE 1773
+++ + +G FQ IL MFIF + T I + + P ++ + C+L + ++++ + + RC+L ++ + + P+ TI ++F L C++ + A SM G +G++F G+ +D +GR I+ GLS M V W L + R F GF F+S +A E+V ++R G + + ++L L AFFIRD L C IS +F F+K ES RWLL T KA++++ ++A+ N+KS+ E E+F + V H I E+F K + V L+ + +F YY + + I+ ++++L + + + C R GR +++ L + A IA I + +I G N + ++ + + G T+F ++++ E FPT++R + + + S +RV +A + + I +LP M F + + LPET +P+ + + + + +E
Sbjct: 6 DQVLERIGQFGPFQKRILAMFMFIFFPLTYQTLIMVFVAYEPPWMCSTNSSACLLSNSTGREIYSTSTQPIELYHR----------RCKLNRTDWKFADPELYEGPV-HTIVTEFDLVCDHSFTAWMANSMLFFGWAIGAIFLGIIADKYGRCSVLFPSAILVMGLSLAMAFVKKA------WLVL--VLRFFIGFFEGGGFLSMFVLATELVGPAKRALAGTLVWIYFTAALMVLALKAFFIRDWSTL----CIISIAPFVFIVLFWKFVPESVRWLLVTGSKGKARRILENVARVNKKSMPEE------ELFAPQ----VEHNRGIIELFSTKRLAVLTLLQCYAWFVNGMVYYGVSMSAGDFGGSIYLNFVLTSLVEFPANVLLIHNCNRFGRKRTVVAYTL-IGA--IACITVSFIPAGTNNLGFIIGRVTGGMLGKLCITTSFNGLYVFSAELFPTMVRNSGMGLLSVISRVGAALAPFVVQLTRIN-AILPFALMGGLTFLAALACWFLPETRGKPTLEVIGDDDPHILE 504
BLAST of slc22a-6 vs. Ensembl Nematostella
Match: EDO39860 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S8P8]) HSP 1 Score: 103.99 bits (258), Expect = 1.467e-23 Identity = 120/513 (23.39%), Postives = 216/513 (42.11%), Query Frame = 1
Query: 238 EKIYQLVGGNSYFQYFILMFIFISQFNTAINILMPIFINNYQDVYCVLPKNQTNQVFTEHRNQFKAINNETGFLIIDSSRCRLTNISSICSEIFVKKYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQIDKYIEIFEEERLRSVSHR----VSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVT--ILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAE 1758
+ + +LVGG + F+ F I + L+ +F Y V P RN C ++ + C+E +TS + S+++L C L + +++M G+ +GSV SD FGR + LS F+++ V+ VS ++ AL R G A + ++ +E+V RT GF ++ +G+ + L +FI + +A LIF +F ES RWL+A K +A ++ A+ NR +V + I ++ +RS +R + + K + V W + + ++ L + +I+ I + + + I F +R GR + L GV L + ++ G +++I + ++ I + T F ++I+ E +PTVIR T + + S AR G++A + V + N +I +A+ + + LPET S + QAE
Sbjct: 11 DDLLRLVGGFGRYPAFLYAFTCIMSVPVGLQQLIQVF-------YAVTPPFDCKGSLPVARN----------------GSCGVSECCANCTEYGFDTSELTSAV-SEWQLVCSRSHLKAMTQAVYMAGLLVGSVTFSSISDHFGRRLSMFLSIFLMAACGIVSGVSDCLSMFALFRFGAGAACAGCLLARYVYCVELVVRKHRTAAGFISNMFVSVGFSSVTLFVYFIHEWRYQLVAVSATGLPLLIFWWFIPESPRWLIAENKLDEAHALLTKFAEKNRVTVDSKHLMHMIREVKKADIRSDDNRKYGMLDLLRTPKLRKRTFICGVNWSVN---ALVFFGLNLNVKNLGGDIYLNFFILCIIEIPAALICWFALQRFGRRIPYCVFMLTGGVAGLLVLAV--PTAKGYQSVIVGLAMIGKICIVMT-FLAIYIFTVELYPTVIRNTGIGVSSMLARFGGILAPYIADVPNVNKNFPLVIFGVLAVAAGILALW-LPETLFSQMSQTVEQAE 492
BLAST of slc22a-6 vs. Ensembl Nematostella
Match: EDO36723 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHW3]) HSP 1 Score: 102.834 bits (255), Expect = 4.039e-23 Identity = 123/535 (22.99%), Postives = 239/535 (44.67%), Query Frame = 1
Query: 238 EKIYQLVGGNSYFQYFIL-MFIFISQFNTAINILM------PIFINNYQDVYCVLPKNQTNQVFTEHRNQFKAINNETGFLIIDSSRCRLTNISSICSEIFVKKYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGR--IIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQR----TNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPF----FYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQIDKYIEIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRV-TILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSG-----TNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEKNFVE 1773
+++ + +G FQ IL MF+FI T +LM P ++ C+L + ++++ + + RC+L ++ + + P+ TI +QF L C+ + A SM G LG++ G+ +D +GR ++ + + FS A + W + R F+GF + S ++ +A E+V ++R T FY++L ++L L A+FI+D +KL C IS V +F F F ES RWLL + +A++++ +AK N+K + + E+ R+ V H E+F + + L+ + + YY + + I+ +++++ + + + C R GR T++ +G I+ +++ +I G + I + +A G T+F ++++ E FPT+IR + + + S +RV +A + + I +LP M+ F + + LPET +P+ + + + +E
Sbjct: 6 DQVLEQIGQFGPFQIRILAMFLFIFIPLTYQTLLMVFVAYEPPWMCTTNSSACLLSNSTGREIYSTSTQPIELYHR----------RCKLNRTDWKFADPELYEGPV-HTIVTQFDLVCDNSFHAWLANSMLFFGWALGAIILGMIADKYGRRSVLFPSAACVIAITFSMSFAQASWVVIAL--RFFSGFFLGGSILTMFVLAAELVGPAKRALSSTMVWFYFTL----ALMVLGLQAYFIKD-WKL---LCIISTVPFVFIFIFWKFIPESVRWLLVVGRKDQAREILEQVAKVNKKEMPK----------EDLRVPVVKHNRGFLELFGTPRLALLTLLQCYAWLVNGLVYYAVSMSAGDFGGSIYLNFVLTSIVEFPANILVIDNCNRFGRKHTVVWYTVVGA----ISCLVVSFIPSGTDNIGYIAGRVAAGTLGKLCITTSFNSLYVFSAELFPTMIRNSGMGLLSVISRVGAALAPFVVQLTRIN-AILPFALMSGLTFLAALACWFLPETRGKPTLEVMGDDDPQHLE 504
BLAST of slc22a-6 vs. Ensembl Nematostella
Match: EDO46087 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RR13]) HSP 1 Score: 99.3673 bits (246), Expect = 4.683e-22 Identity = 114/508 (22.44%), Postives = 217/508 (42.72%), Query Frame = 1
Query: 238 EKIYQLVGGNSYFQYFILMFIFISQFNTAINILMPIFINNYQDVYCVLPKNQTNQVFTEHRNQFKAINNETGFLIIDSSRCRLTNISSICSE-IFVKKYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQIDKYIEIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLS-LQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFE-IAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQ 1752
+ + ++VG Q + + + +S AI +L+ +F+ C+ + TN+ +++ Q C+E + KY ++I +++ L CE + S+ M G LG++ G +D +GR + + VF ++ +P + ++A R TGF + +S +A E+V S R G + +G L+L ++A+ I+D L + + V ++F + ES RWL+ + +A+ +++ IA N +V ++ + F V R ++F + ++ VL FI+F + YY L + ++ +I+ + +L + +F GR L + + L A + + TV MI +F ++IY E FPTV+R + + S +R+ G+ A + ++ + P + I GM M G L +LPET KRP + +
Sbjct: 4 DHVLKIVGEFGPHQRRLYVLLCLSIVPAAIQLLLLVFVAAQPHWICL--NSSTNETCPKNKLQ--------------------------CTERQYTSKY---TSIITEWDLVCENAYKADLVQSLLMSGTLLGALMFGALADKYGRRRVWHTTLTGLVVFGFASSFAPTFKIYATLRFLTGFCIGGEILSAFVLATELVGPSYRGFAGIMAQCFFTLGLLILPMVAYLIQDWRTLSVVLSLPASVFILFFRYVPESARWLMIRGRVSEAENILLDIALKNGIAVPKSLLQVNHPFF-------VGSRYGFFDLFCTRKIVKQTFVLIFIWFVNTLVYYGLSLNTKHLAGDIYMNFFLCSLMEFPAYLTCLFFVNWAGRRKTLFNYMVLAGLACMACMFVQPESSPADRTLATVFAMIGKFGITASFALIYIYSAEIFPTVVRNVGLGVCSMSSRIGGICAPFVVFLGTYMRPLPMVIFGMCAFMAGLLS--LMLPETHKRPLPETMDD 471
BLAST of slc22a-6 vs. Ensembl Medaka
Match: ENSORLT00000022564.2 (solute carrier family 22 member 6 [Source:NCBI gene;Acc:101166767]) HSP 1 Score: 147.902 bits (372), Expect = 1.722e-37 Identity = 127/519 (24.47%), Postives = 244/519 (47.01%), Query Frame = 1
Query: 238 EKIYQLVGGNSYFQYFILMFIFISQFNTAINILMPIFINNYQDVYC---------VLPKNQTNQVFTEHRNQFKAINNETGFLIIDSSRCRLTNISSICS---EIFVKKYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQIDKYIEIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAE 1758
+ I + +GG FQ + ++I + Q A ++L+ +F C +P N ++ F N + D + +S C E + + ST +++ L CE ++++ +S++M G+ +G++ G +D +GR I +S + +VF T AA +P + ++ R G ++S ++ + E + QR G + GY+LL LA+ IRD KLQLA ++ +I+ + +S RWL+A + ++A +V+ A+ N K ++++ I+ ++++ ++ + + S ++ + + N L++++++F YY L S I+ +I L + +R+I +F R +++ L L +G +A + I ++ I+ TVL MI + +++Y E FPTVIR + IGS CAR G++A M + I+P+ P++ + LLPET +P D + E
Sbjct: 4 DDILRTIGGFGRFQKLLYVWICVPQIFLAFHMLVSVFTGAVPPHLCRSSWSSEGPPVPANFSSLSGRPELACFGPGNRSSPGGPADDGQ-----LSGTCQGGWEYSTETF--QSTTVTEWDLVCENASMNNLGSSVYMFGLLVGALVFGNLADKYGRRIIILISLAIQAVFGTAAAFAPNFYVYTALRFMVGTSISGVIMNAFVLGTEWTGLKQRMLAGIITDYFFGFGYILLAGLAYLIRDWRKLQLAISAPGFLFIIYIWVLPKSARWLMANNRVEEALEVIEKAAQMNGKPISKD-IEMCQQVYKADQNSVLKKKHSFIDLVRTPTMRKNSLIVFYLWFVNVLVYYGLSLNISDFGMNIYLTQMIFGLVEMPARTITLFTLNRSRKISQLAFLAVGGSACLLTIFIPSRLF----IVKTVLAMIGKFGITASLSIIYVYSAEVFPTVIRQNGIGIGSMCARTGGVLAPMMYLLRNISPHA-PMVLSGLCPLLGAGLTLLLPETANKPLPDTIEDVE 509
BLAST of slc22a-6 vs. Ensembl Medaka
Match: slc22a6l (solute carrier family 22 member 6 [Source:NCBI gene;Acc:101168641]) HSP 1 Score: 122.479 bits (306), Expect = 4.807e-29 Identity = 114/435 (26.21%), Postives = 201/435 (46.21%), Query Frame = 1
Query: 535 MTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQID-KYIEIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALI----SALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIA-------SQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEKNFVEWRQPWRKSSK 1803
MTS+I S + L C+ +L +++M G+ +G++ G SD +GR I +S +++V T AA SP + L L R G A+S ++ + +E + RT G Y +G LLL +A+FIRD L LA YV + +++ ES RWL K+++A K + +A+FN + ++D K ++ ++ + S S+ ++F+ + + L ++ S SF+YY + K +I+ +I +V + F+ +R + L+ GVT L ++++ Y K + T L ++ +F ++Y GE +PT+IR + S AR+ M+A ++W+ PI+ A+F LPET D + E+ ++ KSSK
Sbjct: 100 MTSSIISDWDLVCDLRSLKQMGQTIYMGGVLVGAIIFGGLSDRYGRRILLLISNMLMAVAGTCAAFSPSFPLFCLFRFGCGMALSGLGLNTFSLIVEWIPTRIRTVTGTITGYCYTLGQLLLAGIAYFIRDWRWLTLAVSLPFYVFFLISWWFHESSRWLALNNKHEEAVKTLKSVARFNGRHEEGEKLDIKMLQESMKKEMSSSKGSYSVLDLFRTPKMRKMTICLSAVWLSTSFAYYGLAMDLQKFGVDIYLIQVIFGAVDIPAKVVITTCMSFIGRRPSQCGALII--AGVTILI--NVVVPY---DKQTLRTCLAVVGKGCLAASFNCCYLYSGELYPTIIRQNGMGWVSMMARIGAMVAPMVLLTGDHIQWLPGFIYGGAPILSGVAAVF--------LPETLGTNLPDTIQDVEERELQ------KSSK 513
BLAST of slc22a-6 vs. Ensembl Medaka
Match: si:dkey-166k12.1 (solute carrier family 22 member 13 [Source:NCBI gene;Acc:101165571]) HSP 1 Score: 122.479 bits (306), Expect = 5.415e-29 Identity = 121/514 (23.54%), Postives = 229/514 (44.55%), Query Frame = 1
Query: 238 EKIYQLVGGNSYFQYFILMFIFISQFNTAINILMPIFI-----NNYQDVYCVLPKNQTNQVFTEHRNQFKAINNETGFLIIDSSRCRLTNISSICSEIFVKKYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTEN-QIDKYIEIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEK 1761
++I +GG +Q + ++I + Q A ++++ IF + +D + NQT + + F A G + R SE+F S+ +++ L C L+S +S++M G+ +GSV G +D +GR LS + +VF A +P + ++ L R G +S ++ + E +R G + +GY+LL +A+ IRD KLQLA ++ + + +S RWLLA + ++A ++ A N + + Q++K+ + +R S V ++ K ++L++I+F YY LG S++ ++ + L + +RS+ + R+++ L +G A ++L N++T + ++ ++ + F +++Y E FPTV+R T + + S AR+ G++A + + +P P+I + LPET RP D L AE
Sbjct: 4 DQILAAIGGFGKYQKILYIWICLPQILLAFHMMVSIFTGATPPHQCRDSFSTGAGNQTLNLSLPDASCFSADALPPGN---RTERVPCGRGWVYSSEVF------ESSTVTEWDLVCNRAGLNSLGSSVYMSGLLVGSVVFGAMADRYGRRFVLLLSIALQTVFGVAVAFAPNFPVYVLLRFAVGTTISGVIINAFVLGTEWTCTKRRMLAGIITDYTFGLGYMLLAGVAYLIRDWRKLQLAISAPGFLLIFYIRVLPQSARWLLANDRTEEAIALLRKAALVNGRVLPPAVQVEKWEILGGSKRSHSAVDLVRTPQMRKRT------VILFYIWFVNVLVYYGLSLGVSRLGTNLYMTQFVFGLIEIPARSLVLIFLPFSRRLSLSGFLAVGGLACL---LMLTVPEDHPNVLTGLAMVGKFGITAS-FAIIYVYTAEIFPTVVRQTGIGVSSMFARMGGVLAPIINMLDSHSPAT-PLIIFGTSPLLGALLALALPETADRPLPDTLEDAEN 497
BLAST of slc22a-6 vs. Ensembl Medaka
Match: oatx (solute carrier family 22 member 6 [Source:NCBI gene;Acc:101155455]) HSP 1 Score: 122.479 bits (306), Expect = 7.540e-29 Identity = 127/541 (23.48%), Postives = 237/541 (43.81%), Query Frame = 1
Query: 241 KIYQLVGGNSYFQYFILMFIFISQFNTAINILMPIFINNYQDVYCVLPKNQT--NQVFTEHRNQFKAINNETGFLIIDSSRCRL-------------------TNISSICSEIFVKKYPMT-----STIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQIDKYIEIFEEERLRSV-SHRVSIK--EVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIIL---KYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEKNF 1767
+ + VGG +Q+ + I + A L+ F++ +C LP NQ+ N ++ + + F+ D S RL NIS + +E V + ST S++ L C L S++M G+ G++ G SD FGR + SY I V + +S ++++ + R G AVS ++ + +E + RT G S + G ++L LA++++D LQL+ ++ + ++Y ES RWL+ ++ + A K + +A+ N K N++ +E+ + + S R S ++ + + + + L ++FS SF+YY + K I+ +I + ++ + + + LGR V+ LF++++I+ ++ + T L + + + +F +++Y GE +PTVIR T + S ARV M A + + E+ P + I+ A+ S F LPET P D + E+ +
Sbjct: 5 DLLEEVGGFGRYQWLHVTLISLPGLMMASQNLLNNFVSGIPAHHCSLPANQSLLNLSLYTQVDEKQLLR---AFIPPDPSGNRLDRCTRFVKPQWHLLTTNSSANISELQTEGCVDGWTFDQSEFISTTVSEWGLVCSLRPLKQMIQSIYMGGVLTGAIIYGSLSDRFGRRLVLIWSYLQIGVLGCSSVLSSSFSVYCIFRFLNGMAVSGVILNGFSLKVEWIPTKTRTVVGTLTSFFFTFGQMILAGLAYWLKDWRMLQLSVSAPHFLFFAYSWWYSESARWLVVNRRSEDALKSLHRVARINGKPEVINKLT--VEVLHSHMRKEIESSRSSFSAIDLMRTRGMRRISICLVAVWFSTSFAYYGLAMDLQKFGVSIYLMQVIFGAVDIPAKLLALGMLSYLGRRVS------QVSCLFLSAVIIFANIFVPTDMQTLRTTLACLGKAFTSASFTTVYLYTGELYPTVIRQTGMGFVSTMARVGSMAAPAVLILDEVWPALPSIVYGGAAVLASGFACF-LPETLNIPLPDTVEDVEEKW 533
BLAST of slc22a-6 vs. Ensembl Medaka
Match: slc22a2 (solute carrier family 22 member 2 [Source:NCBI gene;Acc:101173762]) HSP 1 Score: 108.227 bits (269), Expect = 2.581e-24 Identity = 106/421 (25.18%), Postives = 191/421 (45.37%), Query Frame = 1
Query: 496 SSICSEIFVKKYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQIDKYIEIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAE 1758
++ C E + Y + ++F L C + ++ + +G +GS+ G +D FGR + +S + +V + AVSP YT + R +GF V +++ + EIV + R G + + + +G L+L LLAFFI D LQLA + L + +F ES RWLL+ K + K+ IAK NR+ +++N IE ++ + S+ S ++ + + + L+L + +F+ + Y ++ + ++ LIS L + + +F +R+GR S + A + +I ++ ++ TV+ I F + E +PT +R VS+ S V G++A + + + LP+I F + LLPET P D + E
Sbjct: 114 TTACKEGWEYDYEGRQSFVTEFDLVCSHGWMADMFQATLNVGFLVGSIAIGYLADRFGRKMSFLMSTLVNAVAGILVAVSPNYTSLLVFRSLSGFGVKGGWMAGYVLITEIVGVEFRRTVGVLYQMFFSVGLLILPLLAFFITDWRWLQLAITAPYILFLSYYWFIPESPRWLLSQNKKSQVVKITESIAKENRRVLSKN-----IETLTDD--DADSNSASFMDLIRTPNMRKHTLILSYNWFTSAVVYQGLIMRLGILGGNVYVDFLISGLVEFPAAFLILFTIERIGRRLPFASANMVAGA---SCLITAFLPDDLFLLKTVVACIGRLGITMAFEMVVFVNTELYPTFVRNLGVSVCSTLCDVGGIVAPFLLYRLAVIWLELPLIIFGFLAFLAGGLVLLLPETRGVPLPDSIQDVE 524
BLAST of slc22a-6 vs. Planmine SMEST
Match: SMESG000020910.1 (SMESG000020910.1) HSP 1 Score: 998.038 bits (2579), Expect = 0.000e+0 Identity = 509/513 (99.22%), Postives = 512/513 (99.81%), Query Frame = 1
Query: 292 MFIFISQFNTAINILMPIFINNYQDVYCVLPKNQTNQVFTEHRNQFKAINNETGFLIIDSSRCRLTNISSICSEIFVKKYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQIDKYIEIFEEERLRSVSHRVSIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEKNFVEWRQPWRKSSKKIIDTEIKV 1830
MFIFISQFNTAINILMPIFINNYQDVYCVLPKNQTNQVFTEHRNQFKAI+NETGFLIIDSSRCRLTNISSICSEIFVKKYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATKKYKKAKKVMMHIAKFNRKSVTENQIDKYIEIFEEERLRSVSHRVSIKEVFKYKVVLVNLLVLWFIFFSCSFSYYTFLLGSSKISDEIFTAALISA+GSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEKNF+EWRQPWRK SKKIIDTEIKV
Sbjct: 1 MFIFISQFNTAINILMPIFINNYQDVYCVLPKNQTNQVFTEHRNQFKAIDNETGFLIIDSSRCRLTNISSICSEIFVKKYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATKKYKKAKKVMMHIAKFNRKSVTENQIDKYIEIFEEERLRSVSHRVSIKEVFKYKVVLVNLLVLWFIFFSCSFSYYTFLLGSSKISDEIFTAALISAVGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEKNFIEWRQPWRKGSKKIIDTEIKV 513
BLAST of slc22a-6 vs. Planmine SMEST
Match: SMESG000040243.1 (SMESG000040243.1) HSP 1 Score: 98.9821 bits (245), Expect = 1.592e-21 Identity = 109/468 (23.29%), Postives = 214/468 (45.73%), Query Frame = 1
Query: 457 LIIDSSRCRLTNIS--SICSEIFV-KKYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALG----RLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQIDKYIEIFEEERLRSVSHRV-SIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILL-SLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQ---MEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRP-SSDFLSQAEKNFVEWRQPWRKSSKKIIDTE 1821
LI + SR N++ S CS F+ ST +++ L C+ + S ++F G G+V G SD GR+ ++ ++ VF+ +A + +++++ + L GF+ ++ + E+V S+R G L Y ++L+ L + +++ L L S L + F ES RWLL+ + K+A ++ + K N ++EN + ++ E E ++ + + S+ ++ K K +L+ L +WF + + YY + ++ ++ ++ L + + + + R+GR +L+ SL A ++ + KY +I + MI ++G ++ Y E FPT +R ++ + S AR+ G +A+ ++ F P + I + A+ G L F +PET +P +F + KN R+ K +I+ E
Sbjct: 65 LIANRSRLDFQNVTLDSKCSNGFIYSTQSYGSTAPNEYDLVCDSDYIRSNLKTIFFAGRIFGAVIFGQLSDIIGRL----RTFLIVVVFNLIAGLGLYFSINPIMIGGFLLLQGFSQVGYTLTTFVLGCELVGTSKRKWTGTVLQLFYTAAFILIPLCYWGMQNWRYLALFSGLPSIFFLSYFFIVYESPRWLLSKGRSKEALIIIEKVGKTNHIKLSENLKTEILKHHESEEYKNDTEKKHSVFDLIKSKSMLLLSLNVWFNWIVNALIYYGIIYNVENLAGSLYLNFILLGLVEIPAYVLNLLFLDRIGRRNLLIISLWGTGVACLLSGCVPKY----NTVIIATIAMIGKLTVTMSYGVVYFYTSELFPTTVRNAAMGVSSMSARIGGTMATPILLLDHYFSPLPMI--IFAVLSAVAGGLT--FKMPETKGKPLDQNFHKSSVKN---ERKTAEDDPKPLINDE 517
BLAST of slc22a-6 vs. Planmine SMEST
Match: SMESG000040243.1 (SMESG000040243.1) HSP 1 Score: 98.9821 bits (245), Expect = 1.802e-21 Identity = 109/468 (23.29%), Postives = 214/468 (45.73%), Query Frame = 1
Query: 457 LIIDSSRCRLTNIS--SICSEIFV-KKYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALG----RLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQIDKYIEIFEEERLRSVSHRV-SIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILL-SLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQ---MEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRP-SSDFLSQAEKNFVEWRQPWRKSSKKIIDTE 1821
LI + SR N++ S CS F+ ST +++ L C+ + S ++F G G+V G SD GR+ ++ ++ VF+ +A + +++++ + L GF+ ++ + E+V S+R G L Y ++L+ L + +++ L L S L + F ES RWLL+ + K+A ++ + K N ++EN + ++ E E ++ + + S+ ++ K K +L+ L +WF + + YY + ++ ++ ++ L + + + + R+GR +L+ SL A ++ + KY +I + MI ++G ++ Y E FPT +R ++ + S AR+ G +A+ ++ F P + I + A+ G L F +PET +P +F + KN R+ K +I+ E
Sbjct: 77 LIANRSRLDFQNVTLDSKCSNGFIYSTQSYGSTAPNEYDLVCDSDYIRSNLKTIFFAGRIFGAVIFGQLSDIIGRL----RTFLIVVVFNLIAGLGLYFSINPIMIGGFLLLQGFSQVGYTLTTFVLGCELVGTSKRKWTGTVLQLFYTAAFILIPLCYWGMQNWRYLALFSGLPSIFFLSYFFIVYESPRWLLSKGRSKEALIIIEKVGKTNHIKLSENLKTEILKHHESEEYKNDTEKKHSVFDLIKSKSMLLLSLNVWFNWIVNALIYYGIIYNVENLAGSLYLNFILLGLVEIPAYVLNLLFLDRIGRRNLLIISLWGTGVACLLSGCVPKY----NTVIIATIAMIGKLTVTMSYGVVYFYTSELFPTTVRNAAMGVSSMSARIGGTMATPILLLDHYFSPLPMI--IFAVLSAVAGGLT--FKMPETKGKPLDQNFHKSSVKN---ERKTAEDDPKPLINDE 529
BLAST of slc22a-6 vs. Planmine SMEST
Match: SMESG000040243.1 (SMESG000040243.1) HSP 1 Score: 98.9821 bits (245), Expect = 1.878e-21 Identity = 109/468 (23.29%), Postives = 214/468 (45.73%), Query Frame = 1
Query: 457 LIIDSSRCRLTNIS--SICSEIFV-KKYPMTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGRIIGCGLSYFMISVFSTVAAVSPWYTLHALG----RLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXXXXXXXXVMMHIAKFNRKSVTENQIDKYIEIFEEERLRSVSHRV-SIKEVFKYKXXXXXXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILL-SLQLGVTALFIASIILKYIYGGKNIITTVLLMIAISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQ---MEWVFEIAPNVLPIIGMTMAMFGSLCTFFLLPETFKRP-SSDFLSQAEKNFVEWRQPWRKSSKKIIDTE 1821
LI + SR N++ S CS F+ ST +++ L C+ + S ++F G G+V G SD GR+ ++ ++ VF+ +A + +++++ + L GF+ ++ + E+V S+R G L Y ++L+ L + +++ L L S L + F ES RWLL+ + K+A ++ + K N ++EN + ++ E E ++ + + S+ ++ K K +L+ L +WF + + YY + ++ ++ ++ L + + + + R+GR +L+ SL A ++ + KY +I + MI ++G ++ Y E FPT +R ++ + S AR+ G +A+ ++ F P + I + A+ G L F +PET +P +F + KN R+ K +I+ E
Sbjct: 106 LIANRSRLDFQNVTLDSKCSNGFIYSTQSYGSTAPNEYDLVCDSDYIRSNLKTIFFAGRIFGAVIFGQLSDIIGRL----RTFLIVVVFNLIAGLGLYFSINPIMIGGFLLLQGFSQVGYTLTTFVLGCELVGTSKRKWTGTVLQLFYTAAFILIPLCYWGMQNWRYLALFSGLPSIFFLSYFFIVYESPRWLLSKGRSKEALIIIEKVGKTNHIKLSENLKTEILKHHESEEYKNDTEKKHSVFDLIKSKSMLLLSLNVWFNWIVNALIYYGIIYNVENLAGSLYLNFILLGLVEIPAYVLNLLFLDRIGRRNLLIISLWGTGVACLLSGCVPKY----NTVIIATIAMIGKLTVTMSYGVVYFYTSELFPTTVRNAAMGVSSMSARIGGTMATPILLLDHYFSPLPMI--IFAVLSAVAGGLT--FKMPETKGKPLDQNFHKSSVKN---ERKTAEDDPKPLINDE 558
BLAST of slc22a-6 vs. Planmine SMEST
Match: SMESG000064418.1 (SMESG000064418.1) HSP 1 Score: 85.5001 bits (210), Expect = 2.821e-17 Identity = 122/474 (25.74%), Postives = 218/474 (45.99%), Query Frame = 1
Query: 406 FTEHRNQFKA-INNETGFLIIDSSRCRLTNISSICSEIFVKKYP----MTSTIRSQFKLYCEYHALSSFATSMFMLGICLGSVFGGVFSDTFGR---IIGCGLSYFMISVFSTVAAVSPWYTLHALGRLFTGFAVSVSFVSNSGMALEIVEISQRTNFGFYWSLGYDIGYLLLVLLAFFIRDHFKLQLACCCISYVSLIFPFFYKESFRWLLATXX-XXXXXXVMMHIAKFNRKSVTE--NQIDKYIEIFEEERLRS---VSHRVSIKEVFKYKXXXX---XXXXXWFIFFSCSFSYYTFLLGSSKISDEIFTAALISALGSLVSRSIYMFLCKRLGRVTILLSLQLGVTALFIASIILKYIYGGKNI--ITTVLLMIA-ISVSGTNFGFMWIYGGEAFPTVIRATSVSIGSACARVSGMIASQMEWVFEIAPNVLP--IIGMTMAMFGSLCTFFLLPETFKRPSSDFLSQAEK 1761
FT + FK +NN T I S + N+S +C + V YP + ++I S+F+L C+ + LS S+ + G+ +G + G D FGR IG S F+ + + S TL +G+ F G +S + +ALE + +++ FG + + I + +LA+FIRD LQ+ S++SL+ ES RWL+++ K + V HI + N K+ E + ++K E +++S S R ++ K K + + L V W + + +Y + + + FT S L + I+ F C + R + SLQ+ F+ S +L +NI +TT+L++ ++++G+ F I G +P+ +R VSI +++ + + +F+ + LP I+GM + G L F+ P+ +P S+ + E
Sbjct: 32 FTAGQISFKCQVNNLTMKTNICSWWDNIANMSLVCGKNIVF-YPSDNFVQTSIISRFELVCDQNYLSGLIQSLVIFGMVIGGLIGPTVGDKFGRKSITIG---SMFLSGILGISVSFSNSVTLFGIGKFFLGILREISMTNGCILALEYIPSHKQSLFGMISQIIWSISISFVGMLAYFIRDWDTLQMIGSIPSFLSLVLILIVSESPRWLISSGKFDELDILVKRHIKRSNMKAFMELSDILNKLRSNAENAKMQSRIKYSKRYYPWDILKSKYLTLWTGILTVTW--IYGITATYSLNFITTMVAGNPYFTFCSSSFLDGIA--IIFSFFCLKFSRNLTVFSLQMTSCLCFLISGLLS-----ENIKYVTTILIVFGKMALNGSQFIIS-ISGIYIYPSTLRIFGVSISCTIGKLAAISSPYFVELFK-SGRWLPTTILGMCSMLVGILNVFY--PDWINQPLSETIEDVEN 488 The following BLAST results are available for this feature:
BLAST of slc22a-6 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of slc22a-6 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of slc22a-6 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of slc22a-6 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of slc22a-6 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of slc22a-6 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of slc22a-6 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of slc22a-6 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of slc22a-6 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of slc22a-6 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of slc22a-6 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of slc22a-6 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of slc22a-6 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of slc22a-6 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30020778 ID=SMED30020778|Name=slc22a-6|organism=Schmidtea mediterranea sexual|type=transcript|length=1958bpback to top protein sequence of SMED30020778-orf-1 >SMED30020778-orf-1 ID=SMED30020778-orf-1|Name=SMED30020778-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=534bp MSEKIYQLVGGNSYFQYFILMFIFISQFNTAINILMPIFINNYQDVYCVLback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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