Mitochondrial import inner membrane translocase subunit TIM50

Overview
NameMitochondrial import inner membrane translocase subunit TIM50
Smed IDSMED30020717
Length (bp)1146
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Mitochondrial import inner membrane translocase subunit TIM50 (SMED30020717) t-SNE clustered cells

Violin plots show distribution of expression levels for Mitochondrial import inner membrane translocase subunit TIM50 (SMED30020717) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Mitochondrial import inner membrane translocase subunit TIM50 (SMED30020717) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Mitochondrial import inner membrane translocase subunit TIM50 (SMED30020717) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30020717

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30020717h1SMcG0018824 SmedASXL_011065SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
nervous systemSMED30020717h1SMcG0018824 dd_Smed_v4_1315_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30020717h1SMcG0018824 dd_Smed_v4_1315_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30020717h1SMcG0018824 dd_Smed_v4_1315_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30020717h1SMcG0018824 dd_Smed_v4_1315_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30020717h1SMcG0018824 Contig18510newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30020717h1SMcG0018824 Contig18510uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
neoblastSMED30020717h1SMcG0018824 dd_Smed_v4_2469_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Human
Match: TIMM50 (translocase of inner mitochondrial membrane 50 [Source:HGNC Symbol;Acc:HGNC:23656])

HSP 1 Score: 221.476 bits (563), Expect = 1.314e-68
Identity = 115/279 (41.22%), Postives = 172/279 (61.65%), Query Frame = 3 
Query:  258 SYKLGMVFLCSSFLFSFGYC--VAIYGPPEIKEDGTIKEDKFSSMHPILAYLCRTFSQIKEFQQNIKDPISDKLLPDP--HPQYHP-MTLVLEVNGILLHPEWTYKSGWKFKKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYATVDQPLVEFRQRCEHL-KEHMKEVQELNLKKKKYTF 1076
            SY   +    +  L + G    V I+G   + E+G    D+F +   ++  L RT+   K+++Q I +P S  LLPDP   P Y P  TLVLE+ G+LLHPEW+  +GW+FKKRPG+E   + ++P +E+V+FT+++ M   P++  +DP+   + YRL+R+ATRY  G H+KD+S LNRDP +V+ VD  K A  LQP N   ++ W G+ DDR L+DL+AFL+ +A N + DVR  L++YA  D PL  F+QR   L +E  + + EL+   K+  F
Sbjct:   61 SYAKKVALWLAGLLGAGGTVSVVYIFGNNPVDENGAKIPDEFDNDPILVQQLRRTYKYFKDYRQMIIEPTSPCLLPDPLQEPYYQPPYTLVLELTGVLLHPEWSLATGWRFKKRPGIETLFQQLAPLYEIVIFTSETGMTAFPLIDSVDPH-GFISYRLFRDATRYMDGHHVKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPWDGNSDDRVLLDLSAFLKTIALNGVEDVRTVLEHYALEDDPLAAFKQRQSRLEQEEQQRLAELSKSNKQNLF 338
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Human
Match: TIMM50 (translocase of inner mitochondrial membrane 50 [Source:HGNC Symbol;Acc:HGNC:23656])

HSP 1 Score: 221.09 bits (562), Expect = 3.306e-67
Identity = 115/279 (41.22%), Postives = 172/279 (61.65%), Query Frame = 3 
Query:  258 SYKLGMVFLCSSFLFSFGYC--VAIYGPPEIKEDGTIKEDKFSSMHPILAYLCRTFSQIKEFQQNIKDPISDKLLPDP--HPQYHP-MTLVLEVNGILLHPEWTYKSGWKFKKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYATVDQPLVEFRQRCEHL-KEHMKEVQELNLKKKKYTF 1076
            SY   +    +  L + G    V I+G   + E+G    D+F +   ++  L RT+   K+++Q I +P S  LLPDP   P Y P  TLVLE+ G+LLHPEW+  +GW+FKKRPG+E   + ++P +E+V+FT+++ M   P++  +DP+   + YRL+R+ATRY  G H+KD+S LNRDP +V+ VD  K A  LQP N   ++ W G+ DDR L+DL+AFL+ +A N + DVR  L++YA  D PL  F+QR   L +E  + + EL+   K+  F
Sbjct:  164 SYAKKVALWLAGLLGAGGTVSVVYIFGNNPVDENGAKIPDEFDNDPILVQQLRRTYKYFKDYRQMIIEPTSPCLLPDPLQEPYYQPPYTLVLELTGVLLHPEWSLATGWRFKKRPGIETLFQQLAPLYEIVIFTSETGMTAFPLIDSVDPH-GFISYRLFRDATRYMDGHHVKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPWDGNSDDRVLLDLSAFLKTIALNGVEDVRTVLEHYALEDDPLAAFKQRQSRLEQEEQQRLAELSKSNKQNLF 441
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Human
Match: TIMM50 (translocase of inner mitochondrial membrane 50 [Source:HGNC Symbol;Acc:HGNC:23656])

HSP 1 Score: 171.014 bits (432), Expect = 2.323e-50
Identity = 79/160 (49.38%), Postives = 112/160 (70.00%), Query Frame = 3 
Query:  447 IKDPISDKLLPDP--HPQYHP-MTLVLEVNGILLHPEWTYKSGWKFKKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLR 917
            I +P S  LLPDP   P Y P  TLVLE+ G+LLHPEW+  +GW+FKKRPG+E   + ++P +E+V+FT+++ M   P++  +DP+   + YRL+R+ATRY  G H+KD+S LNRDP +V+ VD  K A  LQP N   ++ W G+ DDR L+DL+AFL+
Sbjct:   99 IIEPTSPCLLPDPLQEPYYQPPYTLVLELTGVLLHPEWSLATGWRFKKRPGIETLFQQLAPLYEIVIFTSETGMTAFPLIDSVDPH-GFISYRLFRDATRYMDGHHVKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPWDGNSDDRVLLDLSAFLK 257
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Human
Match: TIMM50 (translocase of inner mitochondrial membrane 50 [Source:HGNC Symbol;Acc:HGNC:23656])

HSP 1 Score: 169.474 bits (428), Expect = 9.513e-50
Identity = 81/170 (47.65%), Postives = 115/170 (67.65%), Query Frame = 3 
Query:  390 PILAY-LCRTFSQIKEFQQNIKDPISDKLLPDP--HPQYHP-MTLVLEVNGILLHPEWTYKSGWKFKKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDR 887
            PIL   L RT+   K+++Q I +P S  LLPDP   P Y P  TLVLE+ G+LLHPEW+  +GW+FKKRPG+E   + ++P +E+V+FT+++ M   P++  +DP+   + YRL+R+ATRY  G H+KD+S LNRDP +V+ VD  K A  LQP N   ++ W G+ DDR
Sbjct:   88 PILVQQLRRTYKYFKDYRQMIIEPTSPCLLPDPLQEPYYQPPYTLVLELTGVLLHPEWSLATGWRFKKRPGIETLFQQLAPLYEIVIFTSETGMTAFPLIDSVDPH-GFISYRLFRDATRYMDGHHVKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPWDGNSDDR 256
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Human
Match: TIMM50 (translocase of inner mitochondrial membrane 50 [Source:HGNC Symbol;Acc:HGNC:23656])

HSP 1 Score: 153.295 bits (386), Expect = 3.255e-44
Identity = 79/196 (40.31%), Postives = 115/196 (58.67%), Query Frame = 3 
Query:  297 LFSFGYCVAIYGPPEIKEDGTIKEDKFSSMHPILAYLCRTFSQIKEFQQNIKDPISDKLLPDP--HPQYHP-MTLVLEVNGILLHPEWTYKSGWKFKKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGD 875
            L S G C  +  PP    D   +  +++ M P           +      I +P S  LLPDP   P Y P  TLVLE+ G+LLHPEW+  +GW+FKKRPG+E   + ++P +E+V+FT+++ M   P++  +DP+   + YRL+R+ATRY  G H+KD+S LNRDP +V+ VD  K A  LQP N   ++ W G+
Sbjct:   17 LGSRGLCTRLATPPRRAPDQ--ETTRWTKMVPRF---------LMSSTMMIIEPTSPCLLPDPLQEPYYQPPYTLVLELTGVLLHPEWSLATGWRFKKRPGIETLFQQLAPLYEIVIFTSETGMTAFPLIDSVDPH-GFISYRLFRDATRYMDGHHVKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPWDGN 200
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Celegans
Match: scpl-4 (Mitochondrial import inner membrane translocase subunit TIM50 [Source:UniProtKB/Swiss-Prot;Acc:Q22647])

HSP 1 Score: 188.348 bits (477), Expect = 3.077e-55
Identity = 101/256 (39.45%), Postives = 151/256 (58.98%), Query Frame = 3 
Query:  264 KLGMVFLCSSFLFSFGYCVAIYGPPEIKEDGTIKEDKFSSMHPILAYLCRTFSQIKEFQQNIKDPISDKLLPDPHPQYH---PMTLVLEVNGILLHPEWTYKSGWKFKKRPGLELFLEAVS-PFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYATVDQPLVEFRQRCEHL 1019
            ++G   L    +  F      YG  +  E G +  D+FS     LA   R  +  K ++  + +P  ++LLPDP P  +     T+V+E+  IL+HPEWTYK+G++F KRP L+ FL+ +  P FEVV+++++S M   PV+   DP  ++M Y+L+R+ T+Y  G H+KDLS LNRD  KVI +D+D  +  L P N   + +WKG+MDD  LVDLA  L+ +  ++  DVR  L YY+  D P  EFR+R  +L
Sbjct:  167 RIGAYVLFGGSIIGFISFCFYYGRAQRDEFGNVISDEFSG--SFLAPFYRIANSFKLWRDYVVEPAREQLLPDPLPAPYLQPKYTIVIELKNILVHPEWTYKTGYRFLKRPALDYFLDVIGYPNFEVVIYSSESMMTAAPVVDSFDPKQRIM-YKLFRDCTKYMNGHHVKDLSKLNRDLSKVIYIDFDAKSGQLNPENMLRVPEWKGNMDDTSLVDLAELLKTIHLSDAEDVRPMLQYYSQYDDPAKEFRRRAVYL 419
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Celegans
Match: scpl-3 (CTD small phosphatase-like protein 3 [Source:UniProtKB/Swiss-Prot;Acc:Q9N4V4])

HSP 1 Score: 67.3958 bits (163), Expect = 1.211e-12
Identity = 50/174 (28.74%), Postives = 82/174 (47.13%), Query Frame = 3 
Query:  489 PQYHPMTLVLEVNGILLHPEWTYKSGWKF---------------KKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDY 965
            P+Y   TLVL+++  L+H   T                      + RP L  FL  ++  FE+++FT    +  + +   +DP    + +RL+RE      G ++KDL+ L RDP K + +D    + + Q  N   ++ W  D +D EL+ L +FL  + T    DVRE L +
Sbjct:   27 PEY---TLVLDLDETLVHCSLTPLDNATMVFPVVFQNITYQVYVRLRPHLRTFLSRMAKTFEIIIFTASKKVYANKLCDILDPRKNHIRHRLFREHCVCVFGNYVKDLTILGRDPSKTMILDNAVQSFAYQLDNGIPIESWFHDRNDTELLKLCSFLEAIPTLGR-DVREILRH 196
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Celegans
Match: scpl-3 (CTD small phosphatase-like protein 3 [Source:UniProtKB/Swiss-Prot;Acc:Q9N4V4])

HSP 1 Score: 67.0106 bits (162), Expect = 2.385e-12
Identity = 50/172 (29.07%), Postives = 81/172 (47.09%), Query Frame = 3 
Query:  489 PQYHPMTLVLEVNGILLHPEWTYKSGWKF---------------KKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGL 959
            P+Y   TLVL+++  L+H   T                      + RP L  FL  ++  FE+++FT    +  + +   +DP    + +RL+RE      G ++KDL+ L RDP K + +D    + + Q  N   ++ W  D +D EL+ L +FL  + T    DVRE L
Sbjct:   63 PEY---TLVLDLDETLVHCSLTPLDNATMVFPVVFQNITYQVYVRLRPHLRTFLSRMAKTFEIIIFTASKKVYANKLCDILDPRKNHIRHRLFREHCVCVFGNYVKDLTILGRDPSKTMILDNAVQSFAYQLDNGIPIESWFHDRNDTELLKLCSFLEAIPTLGR-DVREIL 230
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Celegans
Match: scpl-1 (CTD small phosphatase-like protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q8T3G2])

HSP 1 Score: 62.3882 bits (150), Expect = 6.030e-11
Identity = 43/144 (29.86%), Postives = 66/144 (45.83%), Query Frame = 3 
Query:  579 KRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYATVDQPLVEFRQRC 1010
            KRP ++ FL  V   FE ++FT   A    PV   +D   ++   RL+REA  + KG ++KDLS L R+  + + +D    + +  P N   +  W  D  D EL+D+   L  +  N    +    D Y   + P  E    C
Sbjct:  111 KRPYVDEFLAKVGEHFECILFTASLAKYADPVADLLDKK-RVFRGRLFREACVFHKGNYVKDLSRLGRNLNQTLIIDNSPASYAFHPENAVPVTTWFDDPSDTELLDILPSLEHL--NGFSSI---YDLYRPEEGPQSELLNHC 248
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Celegans
Match: scpl-1 (CTD small phosphatase-like protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q8T3G2])

HSP 1 Score: 62.3882 bits (150), Expect = 1.262e-10
Identity = 43/144 (29.86%), Postives = 66/144 (45.83%), Query Frame = 3 
Query:  579 KRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYATVDQPLVEFRQRC 1010
            KRP ++ FL  V   FE ++FT   A    PV   +D   ++   RL+REA  + KG ++KDLS L R+  + + +D    + +  P N   +  W  D  D EL+D+   L  +  N    +    D Y   + P  E    C
Sbjct:  206 KRPYVDEFLAKVGEHFECILFTASLAKYADPVADLLDKK-RVFRGRLFREACVFHKGNYVKDLSRLGRNLNQTLIIDNSPASYAFHPENAVPVTTWFDDPSDTELLDILPSLEHL--NGFSSI---YDLYRPEEGPQSELLNHC 343
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Fly
Match: ttm50 (gene:FBgn0250874 transcript:FBtr0347024)

HSP 1 Score: 227.254 bits (578), Expect = 2.389e-70
Identity = 117/274 (42.70%), Postives = 169/274 (61.68%), Query Frame = 3 
Query:  264 KLGMVFLCSSFLFSFGYCVAIYGPPEIKEDGTIKEDKFSSMHPILAYLCRTFSQIKEFQQNIKDPISDKLLPDP------HPQYHPMTLVLEVNGILLHPEWTYKSGWKFKKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYATVDQPLVEFRQRCEHLKEHMKEVQELNLKKKK 1067
            KLG      S + +  + V  +G PE+  +G   ED+F+    +  YL R +  I  +Q+ I++P   KLLPDP       P+Y   TLVLE+  +L+HP+WTY++GW+FKKRPG++ FL   +  FE+VVFT +  M + P+L  +DPN  +M YRL R+AT +  G H+K+L  LNRD +KVI VDWD +A  + P NTF + +W G+ DD +L+DL AFL+++A NN+ DVRE L YY   D P+ +FR+    L E M E + +   K K
Sbjct:  146 KLGFAIFGGSAVAAGFWAVYEFGKPEVDPNGQPIEDEFTHKPLVQQYLQRMWKSIHYYQRMIQEPSRAKLLPDPLKPPYVQPRY---TLVLEMKDVLVHPDWTYQTGWRFKKRPGVDHFLAECAKDFEIVVFTAEQGMTVFPILDALDPNGYIM-YRLVRDATHFVDGHHVKNLDNLNRDLKKVIVVDWDANATKMHPDNTFGLARWHGNDDDGQLLDLIAFLKIIAQNNVDDVREVLHYYRQFDDPINQFRENQRKLAEQMLEAERIEQSKTK 415
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Fly
Match: ttm50 (gene:FBgn0250874 transcript:FBtr0070497)

HSP 1 Score: 227.254 bits (578), Expect = 2.389e-70
Identity = 117/274 (42.70%), Postives = 169/274 (61.68%), Query Frame = 3 
Query:  264 KLGMVFLCSSFLFSFGYCVAIYGPPEIKEDGTIKEDKFSSMHPILAYLCRTFSQIKEFQQNIKDPISDKLLPDP------HPQYHPMTLVLEVNGILLHPEWTYKSGWKFKKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYATVDQPLVEFRQRCEHLKEHMKEVQELNLKKKK 1067
            KLG      S + +  + V  +G PE+  +G   ED+F+    +  YL R +  I  +Q+ I++P   KLLPDP       P+Y   TLVLE+  +L+HP+WTY++GW+FKKRPG++ FL   +  FE+VVFT +  M + P+L  +DPN  +M YRL R+AT +  G H+K+L  LNRD +KVI VDWD +A  + P NTF + +W G+ DD +L+DL AFL+++A NN+ DVRE L YY   D P+ +FR+    L E M E + +   K K
Sbjct:  146 KLGFAIFGGSAVAAGFWAVYEFGKPEVDPNGQPIEDEFTHKPLVQQYLQRMWKSIHYYQRMIQEPSRAKLLPDPLKPPYVQPRY---TLVLEMKDVLVHPDWTYQTGWRFKKRPGVDHFLAECAKDFEIVVFTAEQGMTVFPILDALDPNGYIM-YRLVRDATHFVDGHHVKNLDNLNRDLKKVIVVDWDANATKMHPDNTFGLARWHGNDDDGQLLDLIAFLKIIAQNNVDDVREVLHYYRQFDDPINQFRENQRKLAEQMLEAERIEQSKTK 415
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Fly
Match: ttm2 (gene:FBgn0035124 transcript:FBtr0072507)

HSP 1 Score: 211.075 bits (536), Expect = 3.100e-64
Identity = 107/267 (40.07%), Postives = 168/267 (62.92%), Query Frame = 3 
Query:  264 KLGM-VFLCSSFLFSFGYCVAIYGPPEIKEDGTIKEDKFSSMHPILAYLCRTFSQIKEFQQNIKDPISDKLLPDP-HPQY--HPMTLVLEVNGILLHPEWTYKSGWKFKKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYATVDQPLVEFRQRCEHLKE--HMKEVQE 1046
            KLG  +F   S LFSF + +  YG P + E G    D+FS +  +   + RT+  +  FQ+  K+P   KLLPDP  P Y   P TLVLE+  +L+HP+WTY++GW+FKKRPG+++FL+  + +FE+VV+T +  + + P++  +DPN  +M YRL R++T +  G H+K+L  LNRD ++V+ VDWD+++    P N+F + +W G+ +D  L +L +FL ++ T+ + DVRE L YY      L +FR+    L E  H +EV++
Sbjct:  127 KLGFGLFGIGSMLFSF-WAIYFYGRPSLDEHGNEVIDEFSCLPQMQQLMWRTWKSVNRFQRFFKEPSRKKLLPDPLQPPYVQPPYTLVLEIKDVLVHPDWTYETGWRFKKRPGVDVFLKECAKYFEIVVYTAEQGVTVFPLVDALDPNGCIM-YRLVRDSTHFDGGHHVKNLDNLNRDLKRVVVVDWDRNSTKFHPSNSFSIPRWSGNDNDTTLFELTSFLSVLGTSEIDDVREVLQYYNQFSDSLSQFRENQRKLGELMHAEEVEK 391
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Fly
Match: ttm3 (gene:FBgn0032971 transcript:FBtr0085935)

HSP 1 Score: 181.8 bits (460), Expect = 8.956e-54
Identity = 100/280 (35.71%), Postives = 163/280 (58.21%), Query Frame = 3 
Query:  252 KNSYKLGMVFLCSSFLFSFGYCVAIYGPPEIKEDGTIKEDKFSSMHPILAYLCRTFSQIKEFQQNIKDPISDKLLPDPHPQYH---PMTLVLEVNGILLHPEWTYKSGWKFKKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYATVDQPLVEFRQRCEHLKEHMKE-VQELNLKKKKYTFN 1079
            KN Y   +V    S      + +   G PE    G I ED+FS +     Y+ R +  ++ +++ +++P   +LLP+  P  +   P +LVLE+  +L+HP+WTY++GW+FKKRPG++ FL+  S  FE+V++T++  M   P+L  +DP +  + YRL R AT   +G H K+L  LNRD  +VI VD D +   L P N+ ++ KW G+ DD +L DL AFL+++A + + DVRE L YY   + P+ +F+     L+E  +E +Q L   ++++   
Sbjct:   56 KNFYTYSVVL--GSLFSIVMWAIYKLGKPEEDHRGPI-EDEFSQLPWFRQYIMRMWHTLQYYEKMMEEPQMARLLPNVVPPPYIQPPYSLVLEIKDVLVHPDWTYQTGWRFKKRPGVDYFLQQCSRNFEIVIYTSEQGMTAFPLLDALDP-YGYIKYRLVRGATDLVEGQHTKNLDYLNRDLSRVIVVDCDPYTTPLHPDNSLVLTKWLGNDDDVQLFDLTAFLQLIAEHQVNDVREVLRYYRQFEDPMEQFKDNQRRLQEQSQESIQNLPTSERQWNLT 331
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Fly
Match: CG5830 (gene:FBgn0036556 transcript:FBtr0333579)

HSP 1 Score: 65.0846 bits (157), Expect = 2.505e-11
Identity = 38/116 (32.76%), Postives = 61/116 (52.59%), Query Frame = 3 
Query:  579 KRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMA 926
            KRP ++ FL+ +   +E V+FT   A    PV   +D  + +   RL+RE+  Y +G +IKDL+ L RD +K++ VD    +    P N   +K W  D+ D EL +L      ++
Sbjct:  153 KRPHVDEFLQKMGELYECVLFTASLAKYADPVADLLD-KWNVFRARLFRESCVYYRGNYIKDLNRLGRDLQKIVIVDNSPASYIFHPDNAVPVKSWFDDVTDCELRELIPLFEKLS 267
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Zebrafish
Match: timm50 (translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) [Source:NCBI gene;Acc:393638])

HSP 1 Score: 219.164 bits (557), Expect = 1.915e-67
Identity = 117/289 (40.48%), Postives = 175/289 (60.55%), Query Frame = 3 
Query:  219 DKTGFFSKWTGKNSYKLGMVFLCSSFLFSFGYC--VAIYGPPEIKEDGTIKEDKFSSMHPILAYLCRTFSQIKEFQQNIKDPISDKLLPDP--HPQYHP-MTLVLEVNGILLHPEWTYKSGWKFKKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYATVDQPLVEFRQRCEHL-KEHMKEVQELNLKKKK 1067
            D+ G   K     +Y   MV   +  +   G    V I+G   + E G    D+F +  P++  L RTF   K+++Q I +P S KLLPDP   P Y P  TLVLE+  +LLHPEW+  +GW+FKKRPG++   + ++P +E+V+FT+++ M  +P++  IDP   +M YRL+R+ATRY +G H+KD+S LNRD  KVI VD  + A  LQP N   + KW G+ +DR L DLAAFL+ +A + + DVR  L+ YA  + P+  F++R   L +E  + + E+  +KK+
Sbjct:   83 DEQGEDKKQKENTAYAKKMVLRLAGIMGLGGTVGIVYIFGSNSVDEQGNKIPDEFDNDVPVIQQLRRTFKYFKDYRQMIIEPTSPKLLPDPLREPYYQPPYTLVLELTDVLLHPEWSLATGWRFKKRPGIDYLFQQLAPLYEIVIFTSETGMTAYPLIDSIDPQGFVM-YRLFRDATRYMEGHHVKDVSCLNRDTSKVIVVDCKREAFGLQPFNGLALCKWDGNSEDRTLYDLAAFLKTIAISGVEDVRSVLENYAHEEDPIEAFKRRQAQLAQEEEQRISEMAQQKKQ 370
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Zebrafish
Match: timm50 (translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) [Source:NCBI gene;Acc:393638])

HSP 1 Score: 210.305 bits (534), Expect = 3.332e-64
Identity = 116/289 (40.14%), Postives = 174/289 (60.21%), Query Frame = 3 
Query:  219 DKTGFFSKWTGKNSYKLGMVFLCSSFLFSFGYC--VAIYGPPEIKEDGTIKEDKFSSMHPILAYLCRTFSQIKEFQQNIKDPISDKLLPDP--HPQYHP-MTLVLEVNGILLHPEWTYKSGWKFKKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYATVDQPLVEFRQRCEHL-KEHMKEVQELNLKKKK 1067
            D+ G   K     +Y   MV   +  +   G    V I+G   + E G    +K +   P++  L RTF   K+++Q I +P S KLLPDP   P Y P  TLVLE+  +LLHPEW+  +GW+FKKRPG++   + ++P +E+V+FT+++ M  +P++  IDP   +M YRL+R+ATRY +G H+KD+S LNRD  KVI VD  + A  LQP N   + KW G+ +DR L DLAAFL+ +A + + DVR  L+ YA  + P+  F++R   L +E  + + E+  +KK+
Sbjct:   83 DEQGEDKKQKENTAYAKKMVLRLAGIMGLGGTVGIVYIFGSNSVDEQG----NKVNV--PVIQQLRRTFKYFKDYRQMIIEPTSPKLLPDPLREPYYQPPYTLVLELTDVLLHPEWSLATGWRFKKRPGIDYLFQQLAPLYEIVIFTSETGMTAYPLIDSIDPQGFVM-YRLFRDATRYMEGHHVKDVSCLNRDTSKVIVVDCKREAFGLQPFNGLALCKWDGNSEDRTLYDLAAFLKTIAISGVEDVRSVLENYAHEEDPIEAFKRRQAQLAQEEEQRISEMAQQKKQ 364
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Zebrafish
Match: ctdsplb (CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like b [Source:ZFIN;Acc:ZDB-GENE-060929-488])

HSP 1 Score: 72.7886 bits (177), Expect = 4.542e-14
Identity = 41/116 (35.34%), Postives = 62/116 (53.45%), Query Frame = 3 
Query:  579 KRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMA 926
            KRP ++ FL+ +   FE V+FT   A    PV   +D  + +   RL+RE+  + +G ++KDLS L R+ R VI VD    +    P N   ++ W  DM D EL+DL  F   ++
Sbjct:  137 KRPHVDEFLQKMGELFECVLFTASLAKYADPVADLLD-QWGVFRARLFRESCVFHRGNYVKDLSRLGRELRNVIIVDNSPASYIFHPENAVPVQSWFDDMTDTELLDLLPFFEGLS 251
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Zebrafish
Match: ctdsp1 (CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 [Source:ZFIN;Acc:ZDB-GENE-050522-523])

HSP 1 Score: 70.4774 bits (171), Expect = 2.636e-13
Identity = 44/121 (36.36%), Postives = 63/121 (52.07%), Query Frame = 3 
Query:  579 KRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFL-RMMATNNL 938
            KRP ++ FL+ +   FE V+FT   A    PV   +D  +     RL+RE+  + +G ++KDLS L RD  KVI VD    +    P N   +  W  DM D EL+DL  F  R+   +N+
Sbjct:  135 KRPHVDEFLKRMGELFECVLFTASLAKYADPVSDLLD-KWGAFRSRLFRESCVFHRGNYVKDLSRLGRDLNKVIIVDNSPASYIFHPDNAVPVASWFDDMSDTELLDLIPFFERLSKVDNV 254
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Zebrafish
Match: ctdspl2b (CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2b [Source:NCBI gene;Acc:323089])

HSP 1 Score: 71.633 bits (174), Expect = 3.569e-13
Identity = 44/127 (34.65%), Postives = 67/127 (52.76%), Query Frame = 3 
Query:  582 RPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNN---LPDVRE 953
            RP    FLE +S  +E+++FT    +    +L+ +DP  Q++ +RL+RE     +G +IKDL+ L RD  K I +D    A + Q  N   ++ W  D +D EL+ L  FL  +   N    P VRE
Sbjct:  323 RPFFREFLERMSQIYEIILFTASKKVYADKLLNILDPRKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDRNDSELLKLVPFLEKLVELNEDVRPHVRE 449
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Xenopus
Match: timm50 (translocase of inner mitochondrial membrane 50 homolog [Source:NCBI gene;Acc:100145004])

HSP 1 Score: 204.142 bits (518), Expect = 8.028e-62
Identity = 99/235 (42.13%), Postives = 148/235 (62.98%), Query Frame = 3 
Query:  309 GYCVAIYGPPEIKEDGTIKEDKFSSMHPILAYLCRTFSQIKEFQQNIKDPISDKLLPDP--HPQYHP-MTLVLEVNGILLHPEWTYKSGWKFKKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYATVDQPLVEFRQ 1004
            G  V I+G   + E G    D+F S  P++  + RT+    +++Q I +P S KLLPDP   P Y P  TLVLE+  +LLHPEW+  +GW+FKKR G++   + ++P +E+V+FT+++ +   P++  +DP+   + YRL+R+ATRY  G H+KD+S LNRDP  V+ VD  + A  LQP N   +KKW G  +DR L DL AFL+ +A + + DVR  L+ YA  + PL  F++
Sbjct:   94 GSLVYIFGSNSVDEQGNKIPDEFDSDPPVVQQIRRTYKYFIDYRQMIIEPTSPKLLPDPLKEPYYQPPYTLVLELTDVLLHPEWSLSTGWRFKKRAGIDNLFQQLAPLYEIVIFTSETGLTAFPLIDNVDPH-GFVSYRLFRDATRYTDGHHVKDISCLNRDPSHVVIVDCKREAFKLQPYNGLAIKKWDGSSEDRALYDLTAFLKTIAVSGVSDVRSVLENYALEEDPLEAFKR 327
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Xenopus
Match: timm50 (translocase of inner mitochondrial membrane 50 homolog [Source:NCBI gene;Acc:100145004])

HSP 1 Score: 197.978 bits (502), Expect = 2.034e-59
Identity = 97/235 (41.28%), Postives = 146/235 (62.13%), Query Frame = 3 
Query:  309 GYCVAIYGPPEIKEDGTIKEDKFSSMHPILAYLCRTFSQIKEFQQNIKDPISDKLLPDP--HPQYHP-MTLVLEVNGILLHPEWTYKSGWKFKKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYATVDQPLVEFRQ 1004
            G  V I+G   + E G       +S  P++  + RT+    +++Q I +P S KLLPDP   P Y P  TLVLE+  +LLHPEW+  +GW+FKKR G++   + ++P +E+V+FT+++ +   P++  +DP+   + YRL+R+ATRY  G H+KD+S LNRDP  V+ VD  + A  LQP N   +KKW G  +DR L DL AFL+ +A + + DVR  L+ YA  + PL  F++
Sbjct:   94 GSLVYIFGSNSVDEQGNKVRHYKNSNPPVVQQIRRTYKYFIDYRQMIIEPTSPKLLPDPLKEPYYQPPYTLVLELTDVLLHPEWSLSTGWRFKKRAGIDNLFQQLAPLYEIVIFTSETGLTAFPLIDNVDPH-GFVSYRLFRDATRYTDGHHVKDISCLNRDPSHVVIVDCKREAFKLQPYNGLAIKKWDGSSEDRALYDLTAFLKTIAVSGVSDVRSVLENYALEEDPLEAFKR 327
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Xenopus
Match: timm50 (translocase of inner mitochondrial membrane 50 homolog [Source:NCBI gene;Acc:100145004])

HSP 1 Score: 190.66 bits (483), Expect = 2.359e-56
Identity = 90/208 (43.27%), Postives = 136/208 (65.38%), Query Frame = 3 
Query:  390 PILAYLCRTFSQIKEFQQNIKDPISDKLLPDP--HPQYHP-MTLVLEVNGILLHPEWTYKSGWKFKKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYATVDQPLVEFRQ 1004
            P++  + RT+    +++Q I +P S KLLPDP   P Y P  TLVLE+  +LLHPEW+  +GW+FKKR G++   + ++P +E+V+FT+++ +   P++  +DP+   + YRL+R+ATRY  G H+KD+S LNRDP  V+ VD  + A  LQP N   +KKW G  +DR L DL AFL+ +A + + DVR  L+ YA  + PL  F++
Sbjct:  143 PVVQQIRRTYKYFIDYRQMIIEPTSPKLLPDPLKEPYYQPPYTLVLELTDVLLHPEWSLSTGWRFKKRAGIDNLFQQLAPLYEIVIFTSETGLTAFPLIDNVDPH-GFVSYRLFRDATRYTDGHHVKDISCLNRDPSHVVIVDCKREAFKLQPYNGLAIKKWDGSSEDRALYDLTAFLKTIAVSGVSDVRSVLENYALEEDPLEAFKR 349
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Xenopus
Match: timm50 (translocase of inner mitochondrial membrane 50 homolog [Source:NCBI gene;Acc:100145004])

HSP 1 Score: 157.918 bits (398), Expect = 1.572e-44
Identity = 85/235 (36.17%), Postives = 126/235 (53.62%), Query Frame = 3 
Query:  309 GYCVAIYGPPEIKEDGTIKEDKFSSMHPILAYLCRTFSQIKEFQQNIKDPISDKLLPDP--HPQYHP-MTLVLEVNGILLHPEWTYKSGWKFKKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYATVDQPLVEFRQ 1004
            G  V I+G   + E G    D+F S  P++  + RT+    +++Q I +P S KLLPDP   P Y P  TLVLE+  +LLHPEW+  +GW+FKKR G++   + ++P +E+V+FT+++ +                                  D+S LNRDP  V+ VD  + A  LQP N   +KKW G  +DR L DL AFL+ +A + + DVR  L+ YA  + PL  F++
Sbjct:   94 GSLVYIFGSNSVDEQGNKIPDEFDSDPPVVQQIRRTYKYFIDYRQMIIEPTSPKLLPDPLKEPYYQPPYTLVLELTDVLLHPEWSLSTGWRFKKRAGIDNLFQQLAPLYEIVIFTSETGL----------------------------------DISCLNRDPSHVVIVDCKREAFKLQPYNGLAIKKWDGSSEDRALYDLTAFLKTIAVSGVSDVRSVLENYALEEDPLEAFKR 294
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Xenopus
Match: poln (polymerase (DNA directed) nu [Source:Xenbase;Acc:XB-GENE-988834])

HSP 1 Score: 73.1738 bits (178), Expect = 3.579e-14
Identity = 46/154 (29.87%), Postives = 77/154 (50.00%), Query Frame = 3 
Query:  471 LLPDPHPQ-YHPMTLVLEVNGILLHPEWTYKSGWKFK---------KRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDL 902
            LLP+  P+    + +V++++  L+H  +     + F          KRP ++ FLE +   +E V+FT   A    PV   +D +  +   RL+REA  + +G ++KDLS L RD +K + +D    +    P N   ++ W  DM D EL+ L
Sbjct:   90 LLPEVAPKDKEKICMVIDLDETLVHSSFKVTISYAFPFIIPQVYVLKRPYVDEFLERMGQLYECVLFTASLAKYADPVTDLLDKS-GVFRSRLFREACVFHQGCYVKDLSRLGRDLKKTVILDNSPASYIFHPENAVPVQSWFDDMSDTELLSL 242
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Mouse
Match: Timm50 (translocase of inner mitochondrial membrane 50 [Source:MGI Symbol;Acc:MGI:1913775])

HSP 1 Score: 221.476 bits (563), Expect = 8.927e-69
Identity = 115/276 (41.67%), Postives = 173/276 (62.68%), Query Frame = 3 
Query:  258 SYKLGMVFLCSSFLFSFGYC--VAIYGPPEIKEDGTIKEDKFSSMHPILAYLCRTFSQIKEFQQNIKDPISDKLLPDP--HPQYHP-MTLVLEVNGILLHPEWTYKSGWKFKKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYATVDQPLVEFRQRCEHL-KEHMKEVQELNLKKKK 1067
            SY   +    +  L + G    V I+G   + E+GT   D+F S   ++  L RT+   K+++Q I +P S  LLPDP   P Y P  TLVLE+ G+LLHPEW+  +GW+FKKRPG+E   + ++P +E+V+FT+++ M   P++  +DP+   + YRL+R+ATRY +G H+KD+S LNRDP +V+ VD  K A  LQP N   ++ W G+ DDR L+DL+AFL+ +A N + DVR  L++YA  D PL  F+QR   L +E  + + EL+   ++
Sbjct:   61 SYAKKIALWIAGLLGAGGTVSIVYIFGNNPVDENGTKIPDEFDSDPILVQQLRRTYKYFKDYRQMIIEPTSPCLLPDPLREPYYQPPYTLVLELTGVLLHPEWSLATGWRFKKRPGIETLFQQLAPLYEIVIFTSETGMTAFPLIDSVDPH-GFISYRLFRDATRYMEGHHVKDISCLNRDPARVVVVDCKKEAFRLQPFNGVALRPWDGNSDDRVLLDLSAFLKTIALNQVEDVRTVLEHYALEDDPLEAFKQRQSRLEQEEQQRLAELSKSNRQ 335
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Mouse
Match: Ctdspl (CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like [Source:MGI Symbol;Acc:MGI:1916524])

HSP 1 Score: 71.2478 bits (173), Expect = 1.298e-13
Identity = 41/119 (34.45%), Postives = 63/119 (52.94%), Query Frame = 3 
Query:  579 KRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNN 935
            KRP ++ FL+ +   FE V+FT   A    PV   +D  + +   RL+RE+  + +G ++KDLS L R+  KVI VD    +    P N   ++ W  DM D EL+DL  F   ++  +
Sbjct:  136 KRPHVDEFLQRMGQLFECVLFTASLAKYADPVADLLD-RWGVFRARLFRESCVFHRGNYVKDLSRLGRELSKVIIVDNSPASYIFHPENAVPVQSWFDDMTDTELLDLIPFFEGLSRED 253
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Mouse
Match: Ctdspl (CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like [Source:MGI Symbol;Acc:MGI:1916524])

HSP 1 Score: 71.2478 bits (173), Expect = 1.412e-13
Identity = 41/119 (34.45%), Postives = 63/119 (52.94%), Query Frame = 3 
Query:  579 KRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNN 935
            KRP ++ FL+ +   FE V+FT   A    PV   +D  + +   RL+RE+  + +G ++KDLS L R+  KVI VD    +    P N   ++ W  DM D EL+DL  F   ++  +
Sbjct:  147 KRPHVDEFLQRMGQLFECVLFTASLAKYADPVADLLD-RWGVFRARLFRESCVFHRGNYVKDLSRLGRELSKVIIVDNSPASYIFHPENAVPVQSWFDDMTDTELLDLIPFFEGLSRED 264
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Mouse
Match: Ctdspl2 (CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 [Source:MGI Symbol;Acc:MGI:1196405])

HSP 1 Score: 70.4774 bits (171), Expect = 6.150e-13
Identity = 43/123 (34.96%), Postives = 66/123 (53.66%), Query Frame = 3 
Query:  582 RPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVR 950
            RP    FLE +S  +E+++FT    +    +L+ +DP  Q++ +RL+RE     +G +IKDL+ L RD  K I +D    A + Q  N   ++ W  D +D EL+ L  FL  +   N  DVR
Sbjct:  257 RPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDNELLKLIPFLEKLVELN-EDVR 378
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Mouse
Match: Ctdsp2 (CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 [Source:MGI Symbol;Acc:MGI:1098748])

HSP 1 Score: 68.9366 bits (167), Expect = 1.057e-12
Identity = 41/121 (33.88%), Postives = 63/121 (52.07%), Query Frame = 3 
Query:  579 KRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLA-AFLRMMATNNL 938
            KRP ++ FL  +   FE V+FT   A    PV   +D    +   RL+REA  + +G ++KDLS L RD RK + +D    +    P N   ++ W  DM D EL++L   F  +  T+++
Sbjct:  141 KRPYVDEFLRRMGELFECVLFTASLAKYADPVTDLLD-RCGVFRARLFREACVFHQGCYVKDLSRLGRDLRKTVILDNSPASYIFHPENAVPVQSWFDDMADTELLNLIPVFEELSGTDDV 260
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. UniProt/SwissProt
Match: sp|Q9W4V8|TI50C_DROME (Mitochondrial import inner membrane translocase subunit TIM50-C OS=Drosophila melanogaster OX=7227 GN=ttm50 PE=2 SV=2)

HSP 1 Score: 227.254 bits (578), Expect = 2.395e-69
Identity = 117/274 (42.70%), Postives = 169/274 (61.68%), Query Frame = 3 
Query:  264 KLGMVFLCSSFLFSFGYCVAIYGPPEIKEDGTIKEDKFSSMHPILAYLCRTFSQIKEFQQNIKDPISDKLLPDP------HPQYHPMTLVLEVNGILLHPEWTYKSGWKFKKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYATVDQPLVEFRQRCEHLKEHMKEVQELNLKKKK 1067
            KLG      S + +  + V  +G PE+  +G   ED+F+    +  YL R +  I  +Q+ I++P   KLLPDP       P+Y   TLVLE+  +L+HP+WTY++GW+FKKRPG++ FL   +  FE+VVFT +  M + P+L  +DPN  +M YRL R+AT +  G H+K+L  LNRD +KVI VDWD +A  + P NTF + +W G+ DD +L+DL AFL+++A NN+ DVRE L YY   D P+ +FR+    L E M E + +   K K
Sbjct:  146 KLGFAIFGGSAVAAGFWAVYEFGKPEVDPNGQPIEDEFTHKPLVQQYLQRMWKSIHYYQRMIQEPSRAKLLPDPLKPPYVQPRY---TLVLEMKDVLVHPDWTYQTGWRFKKRPGVDHFLAECAKDFEIVVFTAEQGMTVFPILDALDPNGYIM-YRLVRDATHFVDGHHVKNLDNLNRDLKKVIVVDWDANATKMHPDNTFGLARWHGNDDDGQLLDLIAFLKIIAQNNVDDVREVLHYYRQFDDPINQFRENQRKLAEQMLEAERIEQSKTK 415
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BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. UniProt/SwissProt
Match: sp|Q9D880|TIM50_MOUSE (Mitochondrial import inner membrane translocase subunit TIM50 OS=Mus musculus OX=10090 GN=Timm50 PE=1 SV=1)

HSP 1 Score: 221.476 bits (563), Expect = 6.244e-68
Identity = 115/276 (41.67%), Postives = 173/276 (62.68%), Query Frame = 3 
Query:  258 SYKLGMVFLCSSFLFSFGYC--VAIYGPPEIKEDGTIKEDKFSSMHPILAYLCRTFSQIKEFQQNIKDPISDKLLPDP--HPQYHP-MTLVLEVNGILLHPEWTYKSGWKFKKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYATVDQPLVEFRQRCEHL-KEHMKEVQELNLKKKK 1067
            SY   +    +  L + G    V I+G   + E+GT   D+F S   ++  L RT+   K+++Q I +P S  LLPDP   P Y P  TLVLE+ G+LLHPEW+  +GW+FKKRPG+E   + ++P +E+V+FT+++ M   P++  +DP+   + YRL+R+ATRY +G H+KD+S LNRDP +V+ VD  K A  LQP N   ++ W G+ DDR L+DL+AFL+ +A N + DVR  L++YA  D PL  F+QR   L +E  + + EL+   ++
Sbjct:   61 SYAKKIALWIAGLLGAGGTVSIVYIFGNNPVDENGTKIPDEFDSDPILVQQLRRTYKYFKDYRQMIIEPTSPCLLPDPLREPYYQPPYTLVLELTGVLLHPEWSLATGWRFKKRPGIETLFQQLAPLYEIVIFTSETGMTAFPLIDSVDPH-GFISYRLFRDATRYMEGHHVKDISCLNRDPARVVVVDCKKEAFRLQPFNGVALRPWDGNSDDRVLLDLSAFLKTIALNQVEDVRTVLEHYALEDDPLEAFKQRQSRLEQEEQQRLAELSKSNRQ 335
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BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. UniProt/SwissProt
Match: sp|Q3ZCQ8|TIM50_HUMAN (Mitochondrial import inner membrane translocase subunit TIM50 OS=Homo sapiens OX=9606 GN=TIMM50 PE=1 SV=2)

HSP 1 Score: 221.476 bits (563), Expect = 6.312e-68
Identity = 115/279 (41.22%), Postives = 172/279 (61.65%), Query Frame = 3 
Query:  258 SYKLGMVFLCSSFLFSFGYC--VAIYGPPEIKEDGTIKEDKFSSMHPILAYLCRTFSQIKEFQQNIKDPISDKLLPDP--HPQYHP-MTLVLEVNGILLHPEWTYKSGWKFKKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYATVDQPLVEFRQRCEHL-KEHMKEVQELNLKKKKYTF 1076
            SY   +    +  L + G    V I+G   + E+G    D+F +   ++  L RT+   K+++Q I +P S  LLPDP   P Y P  TLVLE+ G+LLHPEW+  +GW+FKKRPG+E   + ++P +E+V+FT+++ M   P++  +DP+   + YRL+R+ATRY  G H+KD+S LNRDP +V+ VD  K A  LQP N   ++ W G+ DDR L+DL+AFL+ +A N + DVR  L++YA  D PL  F+QR   L +E  + + EL+   K+  F
Sbjct:   61 SYAKKVALWLAGLLGAGGTVSVVYIFGNNPVDENGAKIPDEFDNDPILVQQLRRTYKYFKDYRQMIIEPTSPCLLPDPLQEPYYQPPYTLVLELTGVLLHPEWSLATGWRFKKRPGIETLFQQLAPLYEIVIFTSETGMTAFPLIDSVDPH-GFISYRLFRDATRYMDGHHVKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPWDGNSDDRVLLDLSAFLKTIALNGVEDVRTVLEHYALEDDPLAAFKQRQSRLEQEEQQRLAELSKSNKQNLF 338
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BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. UniProt/SwissProt
Match: sp|Q6NWD4|TIM50_DANRE (Mitochondrial import inner membrane translocase subunit TIM50 OS=Danio rerio OX=7955 GN=timm50 PE=2 SV=2)

HSP 1 Score: 221.476 bits (563), Expect = 1.646e-67
Identity = 118/289 (40.83%), Postives = 176/289 (60.90%), Query Frame = 3 
Query:  219 DKTGFFSKWTGKNSYKLGMVFLCSSFLFSFGYC--VAIYGPPEIKEDGTIKEDKFSSMHPILAYLCRTFSQIKEFQQNIKDPISDKLLPDP--HPQYHP-MTLVLEVNGILLHPEWTYKSGWKFKKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYATVDQPLVEFRQRCEHL-KEHMKEVQELNLKKKK 1067
            D+ G   K     +Y   MV   +  +   G    V I+G   + E G    D+F +  P++  L RTF   K+++Q I +P S KLLPDP   P Y P  TLVLE+  +LLHPEW+  +GW+FKKRPG++   + ++P +E+V+FT+++ M  +P++  IDP   +M YRL+R+ATRY +G H+KD+S LNRD  KVI VD  + A  LQP N   + KW G+ +DR L DLAAFL+ +AT+ + DVR  L+ YA  + P+  F++R   L +E  + + E+  +KK+
Sbjct:   83 DEQGEDKKQKENTAYAKKMVLRLAGIMGLGGTVGIVYIFGSNSVDEQGNKIPDEFDNDVPVIQQLRRTFKYFKDYRQMIIEPTSPKLLPDPLREPYYQPPYTLVLELTDVLLHPEWSLATGWRFKKRPGIDYLFQQLAPLYEIVIFTSETGMTAYPLIDSIDPQGFVM-YRLFRDATRYMEGHHVKDVSCLNRDTSKVIVVDCKREAFGLQPFNGLALCKWDGNSEDRTLYDLAAFLKTIATSGVEDVRSVLENYAHEEDPIEAFKRRQAQLAREEEQRISEMAQQKKQ 370
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BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. UniProt/SwissProt
Match: sp|Q3SZB3|TIM50_BOVIN (Mitochondrial import inner membrane translocase subunit TIM50 OS=Bos taurus OX=9913 GN=TIMM50 PE=2 SV=1)

HSP 1 Score: 219.164 bits (557), Expect = 5.899e-67
Identity = 114/279 (40.86%), Postives = 171/279 (61.29%), Query Frame = 3 
Query:  258 SYKLGMVFLCSSFLFSFGYCVAIY--GPPEIKEDGTIKEDKFSSMHPILAYLCRTFSQIKEFQQNIKDPISDKLLPDP--HPQYHP-MTLVLEVNGILLHPEWTYKSGWKFKKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYATVDQPLVEFRQRCEHL-KEHMKEVQELNLKKKKYTF 1076
            SY   +    +  L + G    IY  G   + E+G    D+F +   ++  L RT+   K+++Q I +P S  LLPDP   P Y P  TLVLE+ G+LLHPEW+  +GW+FKKRPG+E   + ++P +E+V+FT+++ M   P++  +DP+   + YRL+R+ATRY  G H+KD+S LNRDP +V+ VD  K A  LQP N   ++ W G+ DDR L+DL+AFL+ +A N + DVR  L++YA  + PL  F+QR   L +E  + + EL+   K+  F
Sbjct:   63 SYAKKVALWLARLLGAGGTVSVIYIFGNNAVDENGAKIPDEFDNDPILVQQLRRTYKYFKDYRQMIIEPTSPCLLPDPLREPYYQPPYTLVLELTGVLLHPEWSLATGWRFKKRPGIETLFQQLAPLYEIVIFTSETGMTAFPLIDSVDPH-GFISYRLFRDATRYMDGHHVKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPWDGNSDDRVLLDLSAFLKTIALNGVEDVRTVLEHYALEEDPLEAFKQRQSRLEQEEQQRLAELSKSSKQNLF 340
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BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. TrEMBL
Match: A0A4S2KN77 (Mitochondrial import inner membrane translocase subunit TIM50 OS=Opisthorchis felineus OX=147828 GN=CRM22_010756 PE=3 SV=1)

HSP 1 Score: 340.117 bits (871), Expect = 7.494e-112
Identity = 158/273 (57.88%), Postives = 206/273 (75.46%), Query Frame = 3 
Query:  237 SKWTGKNSYKLGMVFLCSSFLFSFGYCVAIYGPPEIKEDGTIKEDKFSSMHPILAYLCRTFSQIKEFQQNIKDPISDKLLPDPHPQYHPM---TLVLEVNGILLHPEWTYKSGWKFKKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYATVDQPLVEFRQRCEHLKEHMKEVQE 1046
            S+W GKN++KLG + L  S LF FG+ VA++GPPE  EDGT+KEDK+S+M P+L Y+CRT++ + +F Q+IKDPIS+KLLPDP    +     TLVLE+NGIL+HP+W +++GW+FKKRP LELFL+ +SP++EVV FTN+SAM   PVL Q+DP  Q +HYRL+REATRY+ G HIKDLS LNRD   VI +DWD  A SLQPRN  ++KKW+G+  DREL+DLAAFLRM+A  N+ D+R  LD+Y   D PL  FR+R E L E   + +E
Sbjct:   58 SRWRGKNAWKLGFLGLTCSGLFGFGFAVALWGPPEKNEDGTLKEDKYSAMTPVLGYICRTWNSLTDFNQSIKDPISEKLLPDPVQPPYYQPPYTLVLELNGILVHPDWKFRTGWRFKKRPALELFLQQLSPYYEVVAFTNESAMTGGPVLMQLDPQGQYIHYRLFREATRYRNGKHIKDLSCLNRDLSHVILIDWDPDAASLQPRNALIVKKWQGNEADRELIDLAAFLRMLAMGNVEDIRLVLDFYRESDDPLGLFRERHEQLMEEQAKRKE 330
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. TrEMBL
Match: A0A504YJM4 (Mitochondrial import inner membrane translocase subunit TIM50 OS=Fasciola gigantica OX=46835 GN=FGIG_00996 PE=3 SV=1)

HSP 1 Score: 328.946 bits (842), Expect = 4.255e-107
Identity = 152/273 (55.68%), Postives = 202/273 (73.99%), Query Frame = 3 
Query:  237 SKWTGKNSYKLGMVFLCSSFLFSFGYCVAIYGPPEIKEDGTIKEDKFSSMHPILAYLCRTFSQIKEFQQNIKDPISDKLLPDPHPQYHPM---TLVLEVNGILLHPEWTYKSGWKFKKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYATVDQPLVEFRQRCEHLKEHMKEVQE 1046
             +W GKN++KLG + L  S LF FG+ VA++GPPE  EDGT+KEDK+S M   +AY+CR +  + +F Q+I+DP+S+KLLPDP    +     TLVLE+N IL+HP+W +++GW+FKKRP LELFL+ +SP++EVV FTN+SAM   PVL Q+DP  Q +HYRL+REATRYK G HIKDLS LNRD  +VI +DWD  A SLQPRN  ++K+WKG+  DREL+DLAAFLRM+A  ++ D+R+ L+YY   D PL  FR+R E L E   + +E
Sbjct:   79 GRWGGKNAWKLGFLSLSCSALFGFGFVVALWGPPEKNEDGTLKEDKYSRMSTPIAYICRAWGSLSDFNQSIRDPVSEKLLPDPVQPPYYQPPYTLVLEINDILVHPDWKFRTGWRFKKRPALELFLQQLSPYYEVVAFTNESAMTGGPVLMQMDPQGQYIHYRLFREATRYKNGKHIKDLSCLNRDLSRVILIDWDSEAASLQPRNALIIKRWKGNESDRELIDLAAFLRMLAMGHVEDIRDVLEYYKGFDDPLALFRERHEQLMEEEAKRRE 351
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. TrEMBL
Match: A0A4E0RK35 (Mitochondrial import inner membrane translocase subunit TIM50 OS=Fasciola hepatica OX=6192 GN=D915_002341 PE=3 SV=1)

HSP 1 Score: 326.25 bits (835), Expect = 3.823e-106
Identity = 150/273 (54.95%), Postives = 202/273 (73.99%), Query Frame = 3 
Query:  237 SKWTGKNSYKLGMVFLCSSFLFSFGYCVAIYGPPEIKEDGTIKEDKFSSMHPILAYLCRTFSQIKEFQQNIKDPISDKLLPDPHPQYHPM---TLVLEVNGILLHPEWTYKSGWKFKKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYATVDQPLVEFRQRCEHLKEHMKEVQE 1046
             +W GKN++KLG + L  S LF FG+ VA++GPPE  EDGT+KED++S M   +AY+CR +  + +F Q+I+DP+S+KLLPDP    +     TLVLE+N IL+HP+W +++GW+FKKRP LELFL+ +SP++EVV FTN+SAM   PVL Q+DP  Q +HYRL+REATRYK G HIKDLS LNRD  +VI +DWD  A SLQPRN  ++K+W+G+  DREL+DLAAFLRM+A  ++ D+R+ L+YY   D PL  FR+R E L E   + +E
Sbjct:   79 GRWGGKNAWKLGFLSLSCSALFGFGFVVALWGPPEKNEDGTLKEDEYSRMSTPIAYICRAWGSLSDFNQSIRDPVSEKLLPDPVQPPYYQPPYTLVLEINDILVHPDWKFRTGWRFKKRPALELFLQQLSPYYEVVAFTNESAMTGGPVLMQMDPQGQYIHYRLFREATRYKNGKHIKDLSCLNRDLSRVILIDWDSEAASLQPRNALIIKRWQGNESDRELIDLAAFLRMLAMGHVEDIRDVLEYYKGFDDPLALFRERHEQLMEEEAKRRE 351
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BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. TrEMBL
Match: C7TXX3 (Mitochondrial import inner membrane translocase subunit TIM50 OS=Schistosoma japonicum OX=6182 GN=EWB00_004813 PE=2 SV=1)

HSP 1 Score: 306.605 bits (784), Expect = 6.312e-99
Identity = 144/266 (54.14%), Postives = 194/266 (72.93%), Query Frame = 3 
Query:  237 SKWTGKNSYKLGMVFLCSSFLFSFGYCVAIYGPPEIKEDGTIKEDKFSSMHPILAYLCRTFSQIKEFQQNIKDPISDKLLPDPHPQYHPM---TLVLEVNGILLHPEWTYKSGWKFKKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYATVDQPLVEFRQRCEHLKE 1025
            S W+G+N++KLG + L  S LF FG+ +A +GPP+  ++G   EDKFS M  I  Y+CR +S + +F Q+IKDP+S+KLLPDP    +     TLV+E+  +L+HP+W +++GW+FKKRP LELFL+ +SP +EVVVFTN+SAM   PVL Q+DP  Q +H+RL+REATRYK+G HIKDLS LNRD  +V+ VDWD  A  LQPRN+ ++K+W GD  D+EL+DLAAFLRM+A  ++ DVR  LDYY   D PL  FR++ E L E
Sbjct:   42 SGWSGRNAWKLGFITLSCSGLFGFGFALATWGPPKKDDNGIEIEDKFSQMPIIWGYICRAWSSLLDFNQSIKDPVSEKLLPDPVQPPYYQPPYTLVMEMTDVLVHPDWKFRTGWRFKKRPALELFLQQLSPHYEVVVFTNESAMTGGPVLAQMDPQGQFIHFRLFREATRYKEGRHIKDLSCLNRDLSRVVLVDWDSTAAQLQPRNSLIIKRWDGDESDKELIDLAAFLRMIAMGSVDDVRLVLDYYREFDDPLAFFREKHEELME 307
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. TrEMBL
Match: C7TXY7 (Mitochondrial import inner membrane translocase subunit TIM50 OS=Schistosoma japonicum OX=6182 PE=2 SV=1)

HSP 1 Score: 306.605 bits (784), Expect = 7.429e-99
Identity = 144/266 (54.14%), Postives = 194/266 (72.93%), Query Frame = 3 
Query:  237 SKWTGKNSYKLGMVFLCSSFLFSFGYCVAIYGPPEIKEDGTIKEDKFSSMHPILAYLCRTFSQIKEFQQNIKDPISDKLLPDPHPQYHPM---TLVLEVNGILLHPEWTYKSGWKFKKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYATVDQPLVEFRQRCEHLKE 1025
            S W+G+N++KLG + L  S LF FG+ +A +GPP+  ++G   EDKFS M  I  Y+CR +S + +F Q+IKDP+S+KLLPDP    +     TLV+E+  +L+HP+W +++GW+FKKRP LELFL+ +SP +EVVVFTN+SAM   PVL Q+DP  Q +H+RL+REATRYK+G HIKDLS LNRD  +V+ VDWD  A  LQPRN+ ++K+W GD  D+EL+DLAAFLRM+A  ++ DVR  LDYY   D PL  FR++ E L E
Sbjct:   42 SGWSGRNAWKLGFITLSCSGLFGFGFALATWGPPKKDDNGIEIEDKFSRMPIIWGYICRAWSSLLDFNQSIKDPVSEKLLPDPVQPPYYQPPYTLVMEMTDVLVHPDWKFRTGWRFKKRPALELFLQQLSPHYEVVVFTNESAMTGGPVLAQMDPQGQFIHFRLFREATRYKEGRHIKDLSCLNRDLSRVVLVDWDSTAAQLQPRNSLIIKRWDGDESDKELIDLAAFLRMIAMGSVDDVRLVLDYYREFDDPLAFFREKHEELME 307
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BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Cavefish
Match: timm50 (translocase of inner mitochondrial membrane 50 [Source:NCBI gene;Acc:103024746])

HSP 1 Score: 222.631 bits (566), Expect = 5.688e-69
Identity = 117/271 (43.17%), Postives = 170/271 (62.73%), Query Frame = 3 
Query:  276 VFLCSSFLFSFGYCVA---IYGPPEIKEDGTIKEDKFSSMHPILAYLCRTFSQIKEFQQNIKDPISDKLLPDP--HPQYHP-MTLVLEVNGILLHPEWTYKSGWKFKKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYATVDQPLVEFRQRCEHLK-EHMKEVQELNLKKKK 1067
            V L  + L   G  V    I+G   + E G    D+F    P++  L RTF   K+++Q I +P S KLLPDP   P Y P  TLVLE+  +LLHPEW+  +GW+FKKRPG++   + ++P +E+V+FT+++ M  +P++  IDP   +M YRL+R+ATRY +G H+KD+S LNRD  KVI VD  + A SLQP N   ++KW G+ +DR L DLAAFL+ +A + + DVR  L+ YA  + P+  F++R   L  E  + + EL+L KK+
Sbjct:  101 VVLRLAGLMGLGGAVGVVYIFGSNSVDEQGNKIPDEFDKEVPVVQQLKRTFRYFKDYRQMIIEPTSPKLLPDPLKEPYYQPPYTLVLELTDVLLHPEWSLATGWRFKKRPGIDYLFQQLAPLYEIVIFTSETGMTAYPLIDSIDPQGFVM-YRLFRDATRYMEGHHVKDVSCLNRDTSKVIVVDCKREAFSLQPFNGMALRKWDGNSEDRTLYDLAAFLKTIAMSGVEDVRTVLENYAHEEDPIEAFKRRQAQLALEEEQRLAELSLHKKQ 370
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Cavefish
Match: timm50 (translocase of inner mitochondrial membrane 50 [Source:NCBI gene;Acc:103024746])

HSP 1 Score: 216.468 bits (550), Expect = 8.021e-67
Identity = 111/254 (43.70%), Postives = 160/254 (62.99%), Query Frame = 3 
Query:  276 VFLCSSFLFSFGYCVA---IYGPPEIKEDGTIKEDKFSSMHPILAYLCRTFSQIKEFQQNIKDPISDKLLPDP--HPQYHP-MTLVLEVNGILLHPEWTYKSGWKFKKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYATVDQPLVEFRQRCEHL 1019
            V L  + L   G  V    I+G   + E G    D+F    P++  L RTF   K+++Q I +P S KLLPDP   P Y P  TLVLE+  +LLHPEW+  +GW+FKKRPG++   + ++P +E+V+FT+++ M  +P++  IDP   +M YRL+R+ATRY +G H+KD+S LNRD  KVI VD  + A SLQP N   ++KW G+ +DR L DLAAFL+ +A + + DVR  L+ YA  + P+  F++R   L
Sbjct:  101 VVLRLAGLMGLGGAVGVVYIFGSNSVDEQGNKIPDEFDKEVPVVQQLKRTFRYFKDYRQMIIEPTSPKLLPDPLKEPYYQPPYTLVLELTDVLLHPEWSLATGWRFKKRPGIDYLFQQLAPLYEIVIFTSETGMTAYPLIDSIDPQGFVM-YRLFRDATRYMEGHHVKDVSCLNRDTSKVIVVDCKREAFSLQPFNGMALRKWDGNSEDRTLYDLAAFLKTIAMSGVEDVRTVLENYAHEEDPIEAFKRRQAQL 353
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Cavefish
Match: ctdspl2b (CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2b [Source:NCBI gene;Acc:323089])

HSP 1 Score: 73.559 bits (179), Expect = 7.017e-14
Identity = 45/127 (35.43%), Postives = 67/127 (52.76%), Query Frame = 3 
Query:  582 RPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNN---LPDVRE 953
            RP    FLE +S  +E+++FT    +    +L+ +DP  Q++ +RL+RE     +G +IKDLS L RD  K I +D    A + Q  N   ++ W  D +D EL+ L  FL  +   N    P VRE
Sbjct:  308 RPFFREFLERMSQIYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLSILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFVDRNDSELLKLVPFLEKLVELNEDVRPHVRE 434
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Cavefish
Match: ctdspl2b (CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2b [Source:NCBI gene;Acc:323089])

HSP 1 Score: 73.1738 bits (178), Expect = 7.497e-14
Identity = 45/127 (35.43%), Postives = 67/127 (52.76%), Query Frame = 3 
Query:  582 RPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNN---LPDVRE 953
            RP    FLE +S  +E+++FT    +    +L+ +DP  Q++ +RL+RE     +G +IKDLS L RD  K I +D    A + Q  N   ++ W  D +D EL+ L  FL  +   N    P VRE
Sbjct:  297 RPFFREFLERMSQIYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLSILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFVDRNDSELLKLVPFLEKLVELNEDVRPHVRE 423
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Cavefish
Match: ctdsplb (CTD small phosphatase-like protein [Source:NCBI gene;Acc:103041610])

HSP 1 Score: 71.2478 bits (173), Expect = 1.342e-13
Identity = 40/116 (34.48%), Postives = 62/116 (53.45%), Query Frame = 3 
Query:  579 KRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMA 926
            KRP ++ FL+ +   FE V+FT   A    PV   +D  + +   RL+RE+  + +G ++KDLS L R+   VI VD    +    P N   ++ W  DM+D EL+DL  F   ++
Sbjct:  148 KRPFVDEFLQKMGELFECVLFTASLAKYADPVADLLD-QWGVFRARLFRESCVFHRGNYVKDLSRLGRELHNVIIVDNSPASYIFHPENAVPVQSWFDDMNDTELLDLLPFFEGLS 262
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Sea Lamprey
Match: timm50 (translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) [Source:NCBI gene;Acc:393638])

HSP 1 Score: 206.068 bits (523), Expect = 1.454e-64
Identity = 104/238 (43.70%), Postives = 150/238 (63.03%), Query Frame = 3 
Query:  318 VAIYGPPEIKEDGTIKEDKFSSMHPILAYLCRTFSQIKEFQQNIKDPISDKLLPDP--HPQYHP-MTLVLEVNGILLHPEWTYKSGWKFKKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYATVDQPLVEFRQRCEHLK 1022
            V ++G   + EDG    D+F +   ++  + R +   K+++Q I +P S KLLPDP   P Y P  TLV+E+  +LLHPEW+  +GW+FKKRPG++  L+ V   FE+VVFT+++ +   P++  IDP   +M YRL+R+ATRY +G H+KDLS LNRD  KVI VD  + A  LQP N   + +W G  DDR L DLA FLR +A + + DVR  L+ Y+  D P+  F++R   L+
Sbjct:   34 VYVFGANALDEDGKEVPDEFDNDPVVVQQVRRAYQYFKDYRQMIIEPTSQKLLPDPLREPYYQPPYTLVIELTDVLLHPEWSLSTGWRFKKRPGIDYLLQQVGQLFEIVVFTSETGLTAFPLVDSIDPQGYIM-YRLFRDATRYLQGQHVKDLSCLNRDMSKVIMVDSKREAFQLQPFNGVALGRWDGSSDDRVLYDLATFLRTIALSGVEDVRTVLENYSMEDNPIEAFKRRQAQLQ 270
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Sea Lamprey
Match: ctdsp2 (CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 [Source:ZFIN;Acc:ZDB-GENE-030131-184])

HSP 1 Score: 68.1662 bits (165), Expect = 2.004e-13
Identity = 53/211 (25.12%), Postives = 90/211 (42.65%), Query Frame = 3 
Query:  318 VAIYGPPEIKEDGTIKEDKFSSMHPILAYLCRTFSQIKEFQQNIKDPISDKLLPDPHP-QYHPMTLVLEVNGILLHPEWTYKSGWKF---------------KKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDL 902
            +AI  P +++E+G +                    + + +   I+ P+   LLP+  P       +V++++  L+H  +       F                KRP ++ FL+ +   FE V+FT   A    PV   +D  + +   RL+RE+  +  G ++KDLS L RD  + I +D    +    P N   +  W  DM D EL+DL
Sbjct:   31 IAIEAPKKVEENGAL------------------LKKCQRYLMPIEIPVERPLLPELRPLDEGKKCMVIDLDETLVHSSFKPIENADFIIPVEIEGTTHQVYVMKRPFVDEFLQRMGELFECVLFTASLAKYADPVADLLD-RWGVFRVRLFRESCVFHHGSYVKDLSRLGRDLSQTIIIDNSPASYIFHPENAVPVGSWFDDMSDMELLDL 222
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BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010797.1 (pep scaffold:Pmarinus_7.0:GL476346:608242:622413:1 gene:ENSPMAG00000009781.1 transcript:ENSPMAT00000010797.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 69.3218 bits (168), Expect = 2.912e-13
Identity = 39/114 (34.21%), Postives = 63/114 (55.26%), Query Frame = 3 
Query:  582 RPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMM 923
            RP    FLE +S  +EV++FT    +    +L+ +DP  +++ +RL+RE     +G ++KDL+ L RD  K I VD    A + Q  N   ++ W  D +D+EL+ L  FL  +
Sbjct:  338 RPHFREFLERMSKIYEVILFTASKKVYADKLLNILDPKKKLVKHRLFREHCVCVQGNYVKDLNILGRDLSKTIIVDNSPQAFAYQLSNGIPIESWFVDKNDKELLKLIPFLETL 451
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001121.1 (pep scaffold:Pmarinus_7.0:GL485372:3962:9133:1 gene:ENSPMAG00000000998.1 transcript:ENSPMAT00000001121.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 68.5514 bits (166), Expect = 4.296e-13
Identity = 42/123 (34.15%), Postives = 66/123 (53.66%), Query Frame = 3 
Query:  582 RPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVR 950
            RP    FLE +S  FE+++FT    +    +L+ +DP  +++ +RL+RE     +G +IKDL+ L RD  K I +D    A + Q  N   ++ W  D  D EL+ L  FL  +   ++ DVR
Sbjct:  237 RPYFREFLERMSKHFEIILFTASKKVYADKLLNILDPAKKLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDRGDTELLKLIPFLERLVRMDV-DVR 358
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005899.1 (pep scaffold:Pmarinus_7.0:GL476522:358859:362945:1 gene:ENSPMAG00000005326.1 transcript:ENSPMAT00000005899.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 64.6994 bits (156), Expect = 6.703e-13
Identity = 39/116 (33.62%), Postives = 59/116 (50.86%), Query Frame = 3 
Query:  579 KRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMA 926
            KRP ++ FL+ +   FE V+FT   A    PV   +D  + +   RL+RE+  +  G ++KDLS L R+  KVI +D    +    P N   +  W  DM D EL+DL      ++
Sbjct:   24 KRPHVDEFLKRMGELFECVLFTASLAKYADPVADLLD-KWGVFRARLFRESCVFHHGNYVKDLSRLGRELNKVIIIDNSPASYIFHPDNAVPVVSWFDDMTDTELLDLVPLFEGLS 138
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Yeast
Match: TIM50 (Essential component of the TIM23 complex; acts as receptor for the translocase of the inner mitochondrial membrane (TIM23) complex guiding incoming precursors from the TOM complex; may control the gating of the Tim23p-Tim17p channel [Source:SGD;Acc:S000005984])

HSP 1 Score: 133.265 bits (334), Expect = 3.007e-35
Identity = 70/173 (40.46%), Postives = 101/173 (58.38%), Query Frame = 3 
Query:  507 TLVLEVNGILLHPEWTYKSGWKFKKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYATVDQPLVEFRQRCEHLKE 1025
            TLV+ +   L+H EW+ K GW+  KRPG + FL  +S ++E+V+F+++  M    +  ++DP    + Y L++E   YK GVHIKDLS LNRD  KVI +D D ++  LQP N   M+ W G+ DD+ LV L  FL  +AT    DVR  L+ +        EF  R + LK+
Sbjct:  193 TLVITLEDFLVHSEWSQKHGWRTAKRPGADYFLGYLSQYYEIVLFSSNYMMYSDKIAEKLDPIHAFVSYNLFKEHCVYKDGVHIKDLSKLNRDLSKVIIIDTDPNSYKLQPENAIPMEPWNGEADDK-LVRLIPFLEYLATQQTKDVRPILNSFEDKKNLAEEFDHRVKKLKD 364
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Yeast
Match: PSR2 (Plasma membrane phosphatase involved in the general stress response; required with Psr1p and Whi2p for full activation of STRE-mediated gene expression, possibly through dephosphorylation of Msn2p; PSR2 has a paralog, PSR1, that arose from the whole genome duplication [Source:SGD;Acc:S000004009])

HSP 1 Score: 83.5741 bits (205), Expect = 2.840e-18
Identity = 52/166 (31.33%), Postives = 84/166 (50.60%), Query Frame = 3 
Query:  510 LVLEVNGILLHPEWTYKSGWKFK---------------KRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLD 962
            L+L+++  L+H  + Y     F                KRPG++ FL  VS  +EVVVFT   +   +P+L  +DPN   +H+RL+REA    +G +IK+LS + R   + I +D    +    P++   +  W  D  D EL+D+   L  +++ N+ DV   LD
Sbjct:  230 LILDLDETLVHSSFKYMHSADFVLPVEIDDQVHNVYVIKRPGVDEFLNRVSQLYEVVVFTASVSRYANPLLDTLDPN-GTIHHRLFREACYNYEGNYIKNLSQIGRPLSETIILDNSPASYIFHPQHAVPISSWFSDTHDNELLDIIPLLEDLSSGNVLDVGSVLD 394
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Yeast
Match: PSR1 (Plasma membrane associated protein phosphatase; involved in the general stress response; required along with binding partner Whi2p for full activation of STRE-mediated gene expression, possibly through dephosphorylation of Msn2p; PSR1 has a paralog, PSR2, that arose from the whole genome duplication [Source:SGD;Acc:S000003933])

HSP 1 Score: 76.6406 bits (187), Expect = 8.396e-16
Identity = 51/166 (30.72%), Postives = 82/166 (49.40%), Query Frame = 3 
Query:  510 LVLEVNGILLHPEWTYKSGWKFK---------------KRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLD 962
            L+L+++  L+H  + Y     F                KRPG+E FLE V   FEVVVFT   +    P+L  +D + +++H+RL+REA    +G +IK+LS + R    +I +D    +    P++   +  W  D  D EL+D+   L  ++     DV + LD
Sbjct:  260 LILDLDETLVHSSFKYLRSADFVLSVEIDDQVHNVYVIKRPGVEEFLERVGKLFEVVVFTASVSRYGDPLLDILDTD-KVIHHRLFREACYNYEGNYIKNLSQIGRPLSDIIILDNSPASYIFHPQHAIPISSWFSDTHDNELLDIIPLLEDLSVKTSLDVGKILD 424
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Yeast
Match: NEM1 (Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme; regulates nuclear growth by controlling phospholipid biosynthesis, required for normal nuclear envelope morphology and sporulation; homolog of the human protein Dullard [Source:SGD;Acc:S000001046])

HSP 1 Score: 45.4394 bits (106), Expect = 8.530e-6
Identity = 35/127 (27.56%), Postives = 58/127 (45.67%), Query Frame = 3 
Query:  579 KRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNF-QMMHYRLYREATRYKKGV-HIKDLSTLNRDPRK----------VIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMM 923
            KRP  +LFL  VS ++++++FT        PV+  ++ +F      R YR     + GV +IKDLS +                VI +D    + ++   N   ++ W  D  D +L++L  FL  M
Sbjct:  298 KRPYCDLFLTKVSKWYDLIIFTASMKEYADPVIDWLESSFPSSFSKRYYRSDCVLRDGVGYIKDLSIVKDSEENGKGSSSSLDDVIIIDNSPVSYAMNVDNAIQVEGWISDPTDTDLLNLLPFLEAM 424
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BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Nematostella
Match: EDO35587 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SL29])

HSP 1 Score: 189.889 bits (481), Expect = 7.359e-59
Identity = 95/209 (45.45%), Postives = 140/209 (66.99%), Query Frame = 3 
Query:  453 DPISDKLLPDPHPQYH---PMTLVLEVNGILLHPEWTYKSGWKFKKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYATVDQPLVEFRQRCEHLKE-HMKEVQELNLKKKK 1067
            +P S KLLPDP P+ +   P TL+LE+  +L+HPE+  KSGW+F+KRPG+E FL  ++P FE+VVFT++   +  PV+  IDP+ QM+ YRL+R+AT+Y KG H+KDLS +NRD +KVI +D +K A  L  RN  ++KKW+G+  D  LVDL   L+ +AT+ + DVR  LD+Y   D  +  F++    L+E     +Q+L  + K+
Sbjct:    4 EPSSTKLLPDPLPEPYIQPPYTLILEMTDVLVHPEYDRKSGWRFRKRPGVEFFLNQLAPLFEIVVFTHEVGFSASPVIDGIDPH-QMIMYRLFRDATKYIKGTHVKDLSGINRDLKKVIVIDCNKAATELNERNAIILKKWEGNPADTTLVDLLPLLQTIATSGVDDVRAVLDFYRQEDDIVAAFKRNQARLREAEQARLQKLEQQNKQ 211
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Nematostella
Match: EDO48206 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RK91])

HSP 1 Score: 77.411 bits (189), Expect = 4.632e-16
Identity = 46/117 (39.32%), Postives = 65/117 (55.56%), Query Frame = 3 
Query:  576 KKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMA 926
            + RP L+ FLE VS  FEV++FT    +    +L+ +DP  +   +RL+RE     +G +IKDLS L RD  K + VD    A + Q  N   ++ W  D  DRELV+L  FL  +A
Sbjct:  143 RTRPHLKYFLERVSKVFEVILFTASKRVYADKLLNILDPEKKYFRHRLFREHCVCVQGNYIKDLSILGRDLSKTMIVDNSPQAFAYQIFNGIPIESWFVDQTDRELVELLPFLEELA 259
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Nematostella
Match: EDO49427 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGH2])

HSP 1 Score: 71.2478 bits (173), Expect = 9.942e-15
Identity = 41/115 (35.65%), Postives = 62/115 (53.91%), Query Frame = 3 
Query:  579 KRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMM 923
            KRP ++ FL+ V   +E V+FT   A    PV   +D  +     RL+RE+  + +G ++KDLS L RD +KV+ +D    + S  P N   +  W  D +D EL++L  FL  M
Sbjct:   61 KRPHVDEFLKRVGQIYECVLFTASLAKYADPVADLLD-KYNTFRARLFRESCVFHRGNYVKDLSKLGRDLKKVLILDNSPASYSFHPENAIPVTSWFDDPNDCELLELIPFLEEM 174
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Nematostella
Match: EDO33173 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SSY7])

HSP 1 Score: 49.2914 bits (116), Expect = 8.407e-7
Identity = 36/133 (27.07%), Postives = 61/133 (45.86%), Query Frame = 3 
Query:  579 KRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYRE------ATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGL 959
            KRP ++ FL+ VS ++++V+FT  +      V   +D N  ++  R +R+         +    + K+LS++  DP  V  +D    +    P N   +K W  D  D  L++L   L   A   + DVR  L
Sbjct:  113 KRPHVDFFLDCVSQWYDLVIFTASTEEYGAAVTDHLDNNRGILKRRYFRQHCSLEFCYNFAYKFYTKNLSSVCDDPTSVFILDNSPDSYKNNPDNAIAIKSWFADPSDTALLNLLPMLD--ALRFVSDVRSVL 243
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Medaka
Match: timm50 (translocase of inner mitochondrial membrane 50 [Source:NCBI gene;Acc:101171018])

HSP 1 Score: 223.016 bits (567), Expect = 3.988e-69
Identity = 120/277 (43.32%), Postives = 170/277 (61.37%), Query Frame = 3 
Query:  255 NSYKLGMVFLCSSFLFSFGYC--VAIYGPPEIKEDGTIKEDKFSSMHPILAYLCRTFSQIKEFQQNIKDPISDKLLPDP--HPQYHP-MTLVLEVNGILLHPEWTYKSGWKFKKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYATVDQPLVEFRQRCEHL-KEHMKEVQELNLKKKK 1067
             +Y   MV   +  +   G    V I+G   + E G    D+F S  P++  L RTF   K+++Q I +P S KLLPDP   P Y P  TLVLE+  +LLHPEW+  +GW+FKKRPG++   + +  ++E+V+FT ++ M  +P++  IDP   +M YRL+R+ATRY +G H+KD+S LNRD  KVI VD  + A SLQP N   +KKW G+ DDR L DLA FL+ +A N + DVR  L+ YA  D P+  F+QR   L +E  + + EL  +KK+
Sbjct:   94 TAYAKKMVLRLAGLMGLGGAVSIVYIFGANSVDEQGIQIPDEFDSDPPVVQQLRRTFKYFKDYRQMIIEPTSPKLLPDPLKEPYYQPPYTLVLELTDVLLHPEWSLSTGWRFKKRPGIDYLFQQLMQYYEIVIFTAETGMTAYPLIDSIDPQGFVM-YRLFRDATRYMEGHHVKDVSCLNRDGSKVIVVDCKREAFSLQPFNGLALKKWDGNSDDRTLYDLAHFLKAIAINKVDDVRSVLENYALEDNPIEAFKQRQAQLAQEEEQRLAELAQQKKQ 369
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Medaka
Match: ctdsplb (CTD small phosphatase-like protein [Source:NCBI gene;Acc:101163607])

HSP 1 Score: 71.633 bits (174), Expect = 5.371e-14
Identity = 40/116 (34.48%), Postives = 62/116 (53.45%), Query Frame = 3 
Query:  579 KRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMA 926
            KRP ++ FL+ +   FE V+FT   A    PV   +D  + +   RL+RE+  + +G ++KDLS L R+   VI VD    +    P N   ++ W  DM+D EL+DL  F   ++
Sbjct:  113 KRPHVDEFLQKMGELFECVLFTASLAKYADPVADLLD-QWGVFRARLFRESCVFHRGNYVKDLSRLGRELNNVIIVDNSPASYIFHPENAVPVQSWFDDMNDTELLDLLPFFEGLS 227
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Medaka
Match: ctdsplb (CTD small phosphatase-like protein [Source:NCBI gene;Acc:101163607])

HSP 1 Score: 71.633 bits (174), Expect = 8.326e-14
Identity = 48/143 (33.57%), Postives = 68/143 (47.55%), Query Frame = 3 
Query:  579 KRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYATVDQPLVEFRQR 1007
            KRP ++ FL+ +   FE V+FT   A    PV   +D  + +   RL+RE+  + +G ++KDLS L R+   VI VD    +    P N   ++ W  DM+D EL+DL  F             EGL     V   L  FR R
Sbjct:  134 KRPHVDEFLQKMGELFECVLFTASLAKYADPVADLLD-QWGVFRARLFRESCVFHRGNYVKDLSRLGRELNNVIIVDNSPASYIFHPENAVPVQSWFDDMNDTELLDLLPFF------------EGLSKEEEVYGVLQNFRSR 263
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Medaka
Match: ctdsplb (CTD small phosphatase-like protein [Source:NCBI gene;Acc:101163607])

HSP 1 Score: 71.633 bits (174), Expect = 9.704e-14
Identity = 40/116 (34.48%), Postives = 62/116 (53.45%), Query Frame = 3 
Query:  579 KRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMA 926
            KRP ++ FL+ +   FE V+FT   A    PV   +D  + +   RL+RE+  + +G ++KDLS L R+   VI VD    +    P N   ++ W  DM+D EL+DL  F   ++
Sbjct:  145 KRPHVDEFLQKMGELFECVLFTASLAKYADPVADLLD-QWGVFRARLFRESCVFHRGNYVKDLSRLGRELNNVIIVDNSPASYIFHPENAVPVQSWFDDMNDTELLDLLPFFEGLS 259
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Medaka
Match: ctdspl2b (CTD small phosphatase like 2 [Source:NCBI gene;Acc:101165541])

HSP 1 Score: 72.4034 bits (176), Expect = 1.094e-13
Identity = 44/127 (34.65%), Postives = 67/127 (52.76%), Query Frame = 3 
Query:  582 RPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNN---LPDVRE 953
            RP    FLE +S  +E+++FT    +    +L+ +DP  Q++ +RL+RE     +G +IKDL+ L RD  K I +D    A + Q  N   ++ W  D +D EL+ L  FL  +   N    P VRE
Sbjct:  245 RPFFREFLERMSQIYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDNELLKLVPFLEKLVEMNEDVRPHVRE 371
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Planmine SMEST
Match: SMESG000025690.1 (SMESG000025690.1)

HSP 1 Score: 676.781 bits (1745), Expect = 0.000e+0
Identity = 334/336 (99.40%), Postives = 335/336 (99.70%), Query Frame = 3 
Query:   75 MLSKFLSASRILNNGSRLISIPKHLYSIEAAKTDAPXXXXXXXXXXXXDKTGFFSKWTGKNSYKLGMVFLCSSFLFSFGYCVAIYGPPEIKEDGTIKEDKFSSMHPILAYLCRTFSQIKEFQQNIKDPISDKLLPDPHPQYHPMTLVLEVNGILLHPEWTYKSGWKFKKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYATVDQPLVEFRQRCEHLKEHMKEVQELNLKKKKYTFNN 1082
            MLSKFLSASRILNNGSRLISIPKHLYSIEAAKTDAPNNSNQSQ NSNSDKTGFFSKWTGKNSYKLGMVFLCSSFLFSFGYCVAIYGPPE+KEDGTIKEDKFSSMHPILAYLCRTFSQIKEFQQNIKDPISDKLLPDPHPQYHPMTLVLEVNGILLHPEWTYKSGWKFKKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYATVDQPLVEFRQRCEHLKEHMKEVQELNLKKKKYTFNN
Sbjct:    1 MLSKFLSASRILNNGSRLISIPKHLYSIEAAKTDAPNNSNQSQENSNSDKTGFFSKWTGKNSYKLGMVFLCSSFLFSFGYCVAIYGPPEMKEDGTIKEDKFSSMHPILAYLCRTFSQIKEFQQNIKDPISDKLLPDPHPQYHPMTLVLEVNGILLHPEWTYKSGWKFKKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYATVDQPLVEFRQRCEHLKEHMKEVQELNLKKKKYTFNN 336
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BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Planmine SMEST
Match: SMESG000001038.1 (SMESG000001038.1)

HSP 1 Score: 75.485 bits (184), Expect = 1.333e-14
Identity = 41/116 (35.34%), Postives = 65/116 (56.03%), Query Frame = 3 
Query:  579 KRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMA 926
            KRP ++LFL  +   FE V+FT   A   +PV   +D +  +  YRL+RE+  + KG  +KDLS L R   +++ +D    +  L P+N   +  W  D+ DR L+DL  +L+ +A
Sbjct:  267 KRPYVDLFLTKMRSLFECVLFTASLAKYANPVADLLDKS-DVFRYRLFRESCIFMKGGFVKDLSMLGRTLDQIVIIDNSPVSFMLHPQNAIQITSWFDDLKDRALLDLIPYLQKLA 381
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BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Planmine SMEST
Match: SMESG000036352.1 (SMESG000036352.1)

HSP 1 Score: 68.9366 bits (167), Expect = 1.717e-12
Identity = 40/120 (33.33%), Postives = 63/120 (52.50%), Query Frame = 3 
Query:  579 KRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNL 938
            KRP ++ FL  +   FE V+FT        PV + +DP  ++   RL+REA  +K G ++KDL  L RD   +I +D    +  L P+N   +  W  D +D  L DL  + + +A++ L
Sbjct:  217 KRPYVDEFLAELGNLFECVLFTASLGKYADPVTNFLDPT-KVFESRLFREACAFKDGNYVKDLDILGRDINSIIILDNSPVSYLLHPKNAVQIVSWFDDQNDTALRDLIPYFKDLASSPL 335
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BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Planmine SMEST
Match: SMESG000043921.1 (SMESG000043921.1)

HSP 1 Score: 63.1586 bits (152), Expect = 9.051e-11
Identity = 36/116 (31.03%), Postives = 60/116 (51.72%), Query Frame = 3 
Query:  579 KRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMA 926
            KRP +++FL+ +   FE V+FT   A    PV   +D  +++  +RL+RE+  + +G ++KDLS L R   +V  +D    +    P N   +  W  D  D  L+DL  +   +A
Sbjct:   24 KRPYVDVFLQRMGRIFECVLFTASLAKYADPVTDFLD-KWRVFRWRLFRESCVFHRGNYVKDLSMLGRQADQVAILDNSPASYMFHPDNAVQITSWFDDPRDTALLDLIPYFEQLA 138
[Close]
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Planmine SMEST
Match: SMESG000043925.1 (SMESG000043925.1)

HSP 1 Score: 62.003 bits (149), Expect = 3.643e-10
Identity = 36/116 (31.03%), Postives = 60/116 (51.72%), Query Frame = 3 
Query:  579 KRPGLELFLEAVSPFFEVVVFTNDSAMNLHPVLHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHACSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMA 926
            KRP +++FL+ +   FE V+FT   A    PV   +D  +++  +RL+RE+  + +G ++KDLS L R   +V  +D    +    P N   +  W  D  D  L+DL  +   +A
Sbjct:  353 KRPYVDVFLQRMGRIFECVLFTASLAKYADPVTDFLD-KWRVFRWRLFRESCVFHRGNYVKDLSMLGRQADQVAILDNSPASYMFHPDNAVQITSWFDDPRDTALLDLIPYFEQLA 467
The following BLAST results are available for this feature:
BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TIMM501.314e-6841.22translocase of inner mitochondrial membrane 50 [So... [more]
TIMM503.306e-6741.22translocase of inner mitochondrial membrane 50 [So... [more]
TIMM502.323e-5049.38translocase of inner mitochondrial membrane 50 [So... [more]
TIMM509.513e-5047.65translocase of inner mitochondrial membrane 50 [So... [more]
TIMM503.255e-4440.31translocase of inner mitochondrial membrane 50 [So... [more]
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BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
scpl-43.077e-5539.45Mitochondrial import inner membrane translocase su... [more]
scpl-31.211e-1228.74CTD small phosphatase-like protein 3 [Source:UniP... [more]
scpl-32.385e-1229.07CTD small phosphatase-like protein 3 [Source:UniP... [more]
scpl-16.030e-1129.86CTD small phosphatase-like protein 1 [Source:UniP... [more]
scpl-11.262e-1029.86CTD small phosphatase-like protein 1 [Source:UniP... [more]
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BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ttm502.389e-7042.70gene:FBgn0250874 transcript:FBtr0347024[more]
ttm502.389e-7042.70gene:FBgn0250874 transcript:FBtr0070497[more]
ttm23.100e-6440.07gene:FBgn0035124 transcript:FBtr0072507[more]
ttm38.956e-5435.71gene:FBgn0032971 transcript:FBtr0085935[more]
CG58302.505e-1132.76gene:FBgn0036556 transcript:FBtr0333579[more]
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BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
timm501.915e-6740.48translocase of inner mitochondrial membrane 50 hom... [more]
timm503.332e-6440.14translocase of inner mitochondrial membrane 50 hom... [more]
ctdsplb4.542e-1435.34CTD (carboxy-terminal domain, RNA polymerase II, p... [more]
ctdsp12.636e-1336.36CTD (carboxy-terminal domain, RNA polymerase II, p... [more]
ctdspl2b3.569e-1334.65CTD (carboxy-terminal domain, RNA polymerase II, p... [more]
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BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
timm508.028e-6242.13translocase of inner mitochondrial membrane 50 hom... [more]
timm502.034e-5941.28translocase of inner mitochondrial membrane 50 hom... [more]
timm502.359e-5643.27translocase of inner mitochondrial membrane 50 hom... [more]
timm501.572e-4436.17translocase of inner mitochondrial membrane 50 hom... [more]
poln3.579e-1429.87polymerase (DNA directed) nu [Source:Xenbase;Acc:X... [more]
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BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Timm508.927e-6941.67translocase of inner mitochondrial membrane 50 [So... [more]
Ctdspl1.298e-1334.45CTD (carboxy-terminal domain, RNA polymerase II, p... [more]
Ctdspl1.412e-1334.45CTD (carboxy-terminal domain, RNA polymerase II, p... [more]
Ctdspl26.150e-1334.96CTD (carboxy-terminal domain, RNA polymerase II, p... [more]
Ctdsp21.057e-1233.88CTD (carboxy-terminal domain, RNA polymerase II, p... [more]
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BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9W4V8|TI50C_DROME2.395e-6942.70Mitochondrial import inner membrane translocase su... [more]
sp|Q9D880|TIM50_MOUSE6.244e-6841.67Mitochondrial import inner membrane translocase su... [more]
sp|Q3ZCQ8|TIM50_HUMAN6.312e-6841.22Mitochondrial import inner membrane translocase su... [more]
sp|Q6NWD4|TIM50_DANRE1.646e-6740.83Mitochondrial import inner membrane translocase su... [more]
sp|Q3SZB3|TIM50_BOVIN5.899e-6740.86Mitochondrial import inner membrane translocase su... [more]
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BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4S2KN777.494e-11257.88Mitochondrial import inner membrane translocase su... [more]
A0A504YJM44.255e-10755.68Mitochondrial import inner membrane translocase su... [more]
A0A4E0RK353.823e-10654.95Mitochondrial import inner membrane translocase su... [more]
C7TXX36.312e-9954.14Mitochondrial import inner membrane translocase su... [more]
C7TXY77.429e-9954.14Mitochondrial import inner membrane translocase su... [more]
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BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
timm505.688e-6943.17translocase of inner mitochondrial membrane 50 [So... [more]
timm508.021e-6743.70translocase of inner mitochondrial membrane 50 [So... [more]
ctdspl2b7.017e-1435.43CTD (carboxy-terminal domain, RNA polymerase II, p... [more]
ctdspl2b7.497e-1435.43CTD (carboxy-terminal domain, RNA polymerase II, p... [more]
ctdsplb1.342e-1334.48CTD small phosphatase-like protein [Source:NCBI ge... [more]
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BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
timm501.454e-6443.70translocase of inner mitochondrial membrane 50 hom... [more]
ctdsp22.004e-1325.12CTD (carboxy-terminal domain, RNA polymerase II, p... [more]
ENSPMAT00000010797.12.912e-1334.21pep scaffold:Pmarinus_7.0:GL476346:608242:622413:1... [more]
ENSPMAT00000001121.14.296e-1334.15pep scaffold:Pmarinus_7.0:GL485372:3962:9133:1 gen... [more]
ENSPMAT00000005899.16.703e-1333.62pep scaffold:Pmarinus_7.0:GL476522:358859:362945:1... [more]
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BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 4
Match NameE-valueIdentityDescription
TIM503.007e-3540.46Essential component of the TIM23 complex; acts as ... [more]
PSR22.840e-1831.33Plasma membrane phosphatase involved in the genera... [more]
PSR18.396e-1630.72Plasma membrane associated protein phosphatase; in... [more]
NEM18.530e-627.56Probable catalytic subunit of Nem1p-Spo7p phosphat... [more]
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BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4
Match NameE-valueIdentityDescription
EDO355877.359e-5945.45Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO482064.632e-1639.32Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO494279.942e-1535.65Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO331738.407e-727.07Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
timm503.988e-6943.32translocase of inner mitochondrial membrane 50 [So... [more]
ctdsplb5.371e-1434.48CTD small phosphatase-like protein [Source:NCBI ge... [more]
ctdsplb8.326e-1433.57CTD small phosphatase-like protein [Source:NCBI ge... [more]
ctdsplb9.704e-1434.48CTD small phosphatase-like protein [Source:NCBI ge... [more]
ctdspl2b1.094e-1334.65CTD small phosphatase like 2 [Source:NCBI gene;Acc... [more]
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BLAST of Mitochondrial import inner membrane translocase subunit TIM50 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000025690.10.000e+099.40SMESG000025690.1[more]
SMESG000001038.11.333e-1435.34SMESG000001038.1[more]
SMESG000036352.11.717e-1233.33SMESG000036352.1[more]
SMESG000043921.19.051e-1131.03SMESG000043921.1[more]
SMESG000043925.13.643e-1031.03SMESG000043925.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30020717 ID=SMED30020717|Name=Mitochondrial import inner membrane translocase subunit TIM50|organism=Schmidtea mediterranea sexual|type=transcript|length=1146bp
GTGTTAATTAGAGTTTATTCATTAGAATTGATTCAACTGTGTTGTTTTAA
TATTTATCACTCTGAATTTTTTTAATGCTTTCTAAATTTTTGAGTGCGTC
AAGAATACTTAACAATGGTTCTAGATTAATAAGTATTCCAAAGCATTTAT
ATAGTATTGAAGCTGCTAAAACTGACGCACCTAATAATTCTAATCAATCA
CAAGCAAATAGTAATTCAGATAAAACTGGTTTCTTTTCAAAATGGACTGG
CAAGAATTCTTATAAATTAGGAATGGTCTTTCTTTGCAGTTCTTTTTTAT
TCAGTTTTGGATATTGTGTAGCTATATATGGTCCTCCAGAAATAAAAGAA
GACGGAACAATCAAAGAAGATAAATTTAGCTCAATGCATCCTATTTTGGC
ATATTTGTGTCGGACATTTAGCCAAATAAAAGAATTTCAACAAAATATCA
AAGATCCGATAAGTGATAAATTACTTCCAGATCCTCATCCTCAATATCAC
CCCATGACATTAGTGTTGGAAGTTAATGGCATATTACTTCACCCTGAGTG
GACGTATAAATCCGGTTGGAAATTTAAAAAACGCCCCGGACTCGAGTTAT
TTCTCGAGGCAGTGTCGCCTTTTTTCGAAGTTGTTGTTTTCACTAATGAT
TCAGCAATGAACCTCCACCCAGTTTTACACCAGATCGACCCGAATTTCCA
GATGATGCATTACCGACTGTATCGGGAAGCTACTCGATACAAAAAGGGTG
TCCATATCAAAGATTTATCGACATTGAACAGAGACCCGAGAAAAGTCATT
CGAGTTGATTGGGATAAACATGCGTGCTCGTTGCAACCGAGAAATACATT
TCTCATGAAAAAATGGAAAGGCGACATGGATGATCGTGAACTGGTTGATT
TAGCCGCATTTCTTAGGATGATGGCGACAAATAACTTACCAGACGTGCGT
GAAGGTCTTGATTATTACGCCACAGTCGATCAGCCTTTAGTTGAGTTCAG
GCAGCGATGTGAACATTTGAAGGAGCACATGAAAGAAGTTCAAGAATTAA
ATTTAAAGAAAAAGAAATATACGTTTAATAATTTAATGCATAAATTAATT
AAATGATTTATACTCAAAATAAATATTTACAACGTTTAAAAAAAAA
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protein sequence of SMED30020717-orf-1

>SMED30020717-orf-1 ID=SMED30020717-orf-1|Name=SMED30020717-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=344bp
MLSKFLSASRILNNGSRLISIPKHLYSIEAAKTDAPNNSNQSQANSNSDK
TGFFSKWTGKNSYKLGMVFLCSSFLFSFGYCVAIYGPPEIKEDGTIKEDK
FSSMHPILAYLCRTFSQIKEFQQNIKDPISDKLLPDPHPQYHPMTLVLEV
NGILLHPEWTYKSGWKFKKRPGLELFLEAVSPFFEVVVFTNDSAMNLHPV
LHQIDPNFQMMHYRLYREATRYKKGVHIKDLSTLNRDPRKVIRVDWDKHA
CSLQPRNTFLMKKWKGDMDDRELVDLAAFLRMMATNNLPDVREGLDYYAT
VDQPLVEFRQRCEHLKEHMKEVQELNLKKKKYTFNNLMHKLIK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0005739mitochondrion
GO:0005743mitochondrial inner membrane
GO:0005744mitochondrial inner membrane presequence translocase complex
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000429neoblast
PLANA:0002109X1 cell
Vocabulary: INTERPRO
TermDefinition
IPR027111Tim50
IPR036412HAD-like_sf
IPR004274FCP1_dom
IPR023214HAD_sf
Vocabulary: biological process
TermDefinition
GO:0015031protein transport
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 305..335
NoneNo IPR availablePANTHERPTHR12210NUCLEAR LIM INTERACTOR-INTERACTING FACTOR-RELATEDcoord: 41..321
NoneNo IPR availableCDDcd07521HAD_FCP1-likecoord: 143..261
e-value: 7.25873E-37
score: 127.326
NoneNo IPR availableTMHMMTMhelixcoord: 65..87
IPR004274FCP1 homology domainSMARTSM00577forpap2coord: 142..271
e-value: 1.5E-39
score: 147.4
IPR004274FCP1 homology domainPFAMPF03031NIFcoord: 145..292
e-value: 1.5E-36
score: 125.5
IPR004274FCP1 homology domainPROSITEPS50969FCP1coord: 139..283
score: 31.862
IPR023214HAD superfamilyGENE3DG3DSA:3.40.50.1000coord: 130..314
e-value: 3.7E-54
score: 184.7
IPR027111Mitochondrial import inner membrane translocase subunit Tim50PANTHERPTHR12210:SF3MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM50coord: 41..321
IPR036412HAD-like superfamilySUPERFAMILYSSF56784HAD-likecoord: 135..295