G-protein, gamma subunit,domain-containing protein

Overview
NameG-protein, gamma subunit,domain-containing protein
Smed IDSMED30020678
Length (bp)657
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of G-protein, gamma subunit,domain-containing protein (SMED30020678) t-SNE clustered cells

Violin plots show distribution of expression levels for G-protein, gamma subunit,domain-containing protein (SMED30020678) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of G-protein, gamma subunit,domain-containing protein (SMED30020678) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for G-protein, gamma subunit,domain-containing protein (SMED30020678) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30020678

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 12

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
headSMED30020678SMESG000066557.1 SmedASXL_006695SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
protonephridiaSMED30020678SMESG000066557.1 dd_Smed_v4_1237_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
neuronSMED30020678SMESG000066557.1 dd_Smed_v4_1237_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
neuronSMED30020678SMESG000066557.1 dd_Smed_v4_1237_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult colorimetric in situ hybridization evidence
muscle cellSMED30020678SMESG000066557.1 dd_Smed_v4_1237_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30020678SMESG000066557.1 dd_Smed_v4_1237_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
headSMED30020678SMESG000066557.1 dd_Smed_v6_1237_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
photoreceptor neuronSMED30020678SMESG000066557.1 SMED30020678smed_20140614PMID:22884275
Lapan et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
neuronSMED30020678SMESG000066557.1 dd_Smed_v6_1237_0dd_Smed_v6PMID:29674432
Plass et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cholinergic neuronSMED30020678SMESG000066557.1 dd_Smed_v6_1237_0dd_Smed_v6PMID:29674432
Plass et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
GABAergic neuronSMED30020678SMESG000066557.1 dd_Smed_v6_1237_0dd_Smed_v6PMID:29674432
Plass et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30020678SMESG000066557.1 dd_Smed_v6_1237_0dd_Smed_v6PMID:29674432
Plass et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Human
Match: GNG7 (G protein subunit gamma 7 [Source:HGNC Symbol;Acc:HGNC:4410])

HSP 1 Score: 51.6026 bits (122), Expect = 1.074e-8
Identity = 27/65 (41.54%), Postives = 41/65 (63.08%), Query Frame = 3
Query:  147 SGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
            + I+Q +KLVEQLR EA I R  VS +  +++ Y +++   D L+ G     +NPF++K  CIIL
Sbjct:    5 NNIAQARKLVEQLRIEAGIERIKVSKAASDLMSYCEQHARNDPLLVGVP-ASENPFKDKKPCIIL 68          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Human
Match: GNG12 (G protein subunit gamma 12 [Source:HGNC Symbol;Acc:HGNC:19663])

HSP 1 Score: 49.6766 bits (117), Expect = 5.877e-8
Identity = 25/64 (39.06%), Postives = 40/64 (62.50%), Query Frame = 3
Query:  150 GISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
             I+Q ++ V+QLR EA+I R  VS +  +++ Y +E+   D L+ G     +NPF++K  CIIL
Sbjct:   10 NIAQARRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTS-ENPFKDKKTCIIL 72          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Human
Match: GNG11 (G protein subunit gamma 11 [Source:HGNC Symbol;Acc:HGNC:4403])

HSP 1 Score: 48.9062 bits (115), Expect = 1.459e-7
Identity = 25/55 (45.45%), Postives = 34/55 (61.82%), Query Frame = 3
Query:  174 VEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCII 338
            VEQLR E  + R+ VS   +E+  Y++E   +D LV G    K NPF+EKG C+I
Sbjct:   19 VEQLRKEVKLQRQQVSKCSEEIKNYIEERSGEDPLVKGIPEDK-NPFKEKGSCVI 72          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Human
Match: GNGT2 (G protein subunit gamma transducin 2 [Source:HGNC Symbol;Acc:HGNC:4412])

HSP 1 Score: 44.669 bits (104), Expect = 4.549e-6
Identity = 22/55 (40.00%), Postives = 33/55 (60.00%), Query Frame = 3
Query:  174 VEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCII 338
            VEQL+ E    R P+S + +E+ +Y++     D  + G    K NPF+EKGGC+I
Sbjct:   15 VEQLKKEVKNTRIPISKAGKEIKEYVEAQAGNDPFLKGIPEDK-NPFKEKGGCLI 68          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Human
Match: GNGT2 (G protein subunit gamma transducin 2 [Source:HGNC Symbol;Acc:HGNC:4412])

HSP 1 Score: 44.669 bits (104), Expect = 4.549e-6
Identity = 22/55 (40.00%), Postives = 33/55 (60.00%), Query Frame = 3
Query:  174 VEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCII 338
            VEQL+ E    R P+S + +E+ +Y++     D  + G    K NPF+EKGGC+I
Sbjct:   15 VEQLKKEVKNTRIPISKAGKEIKEYVEAQAGNDPFLKGIPEDK-NPFKEKGGCLI 68          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Celegans
Match: gpc-1 (Guanine nucleotide-binding protein subunit gamma [Source:UniProtKB/Swiss-Prot;Acc:P54406])

HSP 1 Score: 48.9062 bits (115), Expect = 3.577e-8
Identity = 27/59 (45.76%), Postives = 37/59 (62.71%), Query Frame = 3
Query:  165 KKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
            K   EQL AEA I R+ VS   +E++ + ++NK  D LVSG  ++  NPFQEK  C +L
Sbjct:    5 KASTEQLCAEANIQRKKVSEVSKELLDFCEKNKTNDMLVSGPTDQH-NPFQEKKSCSVL 62          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Celegans
Match: gpc-1 (Guanine nucleotide-binding protein subunit gamma [Source:UniProtKB/Swiss-Prot;Acc:P54406])

HSP 1 Score: 48.9062 bits (115), Expect = 3.577e-8
Identity = 27/59 (45.76%), Postives = 37/59 (62.71%), Query Frame = 3
Query:  165 KKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
            K   EQL AEA I R+ VS   +E++ + ++NK  D LVSG  ++  NPFQEK  C +L
Sbjct:    5 KASTEQLCAEANIQRKKVSEVSKELLDFCEKNKTNDMLVSGPTDQH-NPFQEKKSCSVL 62          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Celegans
Match: gpc-1 (Guanine nucleotide-binding protein subunit gamma [Source:UniProtKB/Swiss-Prot;Acc:P54406])

HSP 1 Score: 48.9062 bits (115), Expect = 3.577e-8
Identity = 27/59 (45.76%), Postives = 37/59 (62.71%), Query Frame = 3
Query:  165 KKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
            K   EQL AEA I R+ VS   +E++ + ++NK  D LVSG  ++  NPFQEK  C +L
Sbjct:    5 KASTEQLCAEANIQRKKVSEVSKELLDFCEKNKTNDMLVSGPTDQH-NPFQEKKSCSVL 62          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Fly
Match: Ggamma1 (gene:FBgn0004921 transcript:FBtr0088645)

HSP 1 Score: 70.8626 bits (172), Expect = 3.508e-16
Identity = 30/65 (46.15%), Postives = 49/65 (75.38%), Query Frame = 3
Query:  147 SGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
            S + QQ+ +VEQLR EAAI+R+ +S S  +M++Y+ E++ +D L++GF ++K NPF+EK  C +L
Sbjct:    6 SSLQQQRVVVEQLRREAAIDRQTISESCAKMMKYITEHEQEDYLLTGFTSQKVNPFREKSSCTVL 70          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Fly
Match: Ggamma1 (gene:FBgn0004921 transcript:FBtr0088647)

HSP 1 Score: 70.8626 bits (172), Expect = 3.508e-16
Identity = 30/65 (46.15%), Postives = 49/65 (75.38%), Query Frame = 3
Query:  147 SGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
            S + QQ+ +VEQLR EAAI+R+ +S S  +M++Y+ E++ +D L++GF ++K NPF+EK  C +L
Sbjct:    6 SSLQQQRVVVEQLRREAAIDRQTISESCAKMMKYITEHEQEDYLLTGFTSQKVNPFREKSSCTVL 70          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Fly
Match: Ggamma1 (gene:FBgn0004921 transcript:FBtr0088646)

HSP 1 Score: 70.8626 bits (172), Expect = 3.508e-16
Identity = 30/65 (46.15%), Postives = 49/65 (75.38%), Query Frame = 3
Query:  147 SGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
            S + QQ+ +VEQLR EAAI+R+ +S S  +M++Y+ E++ +D L++GF ++K NPF+EK  C +L
Sbjct:    6 SSLQQQRVVVEQLRREAAIDRQTISESCAKMMKYITEHEQEDYLLTGFTSQKVNPFREKSSCTVL 70          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Fly
Match: CG43324 (gene:FBgn0263029 transcript:FBtr0306907)

HSP 1 Score: 61.6178 bits (148), Expect = 9.611e-13
Identity = 29/65 (44.62%), Postives = 44/65 (67.69%), Query Frame = 3
Query:  147 SGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
            + + QQ+ +  QLR E  + R PVS +   M++YM E++++DCL+SGF  +K NPF+EK  C IL
Sbjct:    3 ANLQQQRSINLQLRREVEMERMPVSVACSLMMKYMLEHEEEDCLLSGFT-QKVNPFREKSSCSIL 66          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Fly
Match: Ggamma30A (gene:FBgn0267252 transcript:FBtr0336620)

HSP 1 Score: 53.1434 bits (126), Expect = 1.676e-9
Identity = 23/59 (38.98%), Postives = 42/59 (71.19%), Query Frame = 3
Query:  165 KKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
            KK +E ++ +A++ R P+S S+ EM  +++EN+  D L++   +KK+NP+ EKG C+I+
Sbjct:    7 KKQIENMKYQASMERWPLSKSIAEMRSFIEENEKNDPLINA-PDKKNNPWAEKGKCVIM 64          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Zebrafish
Match: si:dkey-117i10.1 (si:dkey-117i10.1 [Source:ZFIN;Acc:ZDB-GENE-091204-371])

HSP 1 Score: 52.7582 bits (125), Expect = 2.650e-9
Identity = 24/68 (35.29%), Postives = 43/68 (63.24%), Query Frame = 3
Query:  138 Y*MSGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
            Y  + + Q ++ VEQLR E  + R  +SA+ ++++QY  E++  D L++G A    NPF++K  C++L
Sbjct:    4 YCSNNVLQARRAVEQLRMETELQRIKISAAAEQLVQYCQEHRRADPLLTGIA-ASSNPFKDKKTCVLL 70          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Zebrafish
Match: gng7 (guanine nucleotide binding protein (G protein), gamma 7 [Source:ZFIN;Acc:ZDB-GENE-040718-93])

HSP 1 Score: 52.373 bits (124), Expect = 3.887e-9
Identity = 27/63 (42.86%), Postives = 40/63 (63.49%), Query Frame = 3
Query:  153 ISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
            I+Q +KLVEQLR EA I R  VS +  +++ Y +++   D L+ G     +NPF++K  CIIL
Sbjct:    7 IAQARKLVEQLRIEAGIERIKVSKAAADLMSYCEQHARSDPLLVGVPT-SENPFKDKKPCIIL 68          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Zebrafish
Match: gng7 (guanine nucleotide binding protein (G protein), gamma 7 [Source:ZFIN;Acc:ZDB-GENE-040718-93])

HSP 1 Score: 52.373 bits (124), Expect = 3.887e-9
Identity = 27/63 (42.86%), Postives = 40/63 (63.49%), Query Frame = 3
Query:  153 ISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
            I+Q +KLVEQLR EA I R  VS +  +++ Y +++   D L+ G     +NPF++K  CIIL
Sbjct:    7 IAQARKLVEQLRIEAGIERIKVSKAAADLMSYCEQHARSDPLLVGVPT-SENPFKDKKPCIIL 68          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Zebrafish
Match: gngt1 (guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 [Source:ZFIN;Acc:ZDB-GENE-030131-7596])

HSP 1 Score: 51.9878 bits (123), Expect = 6.083e-9
Identity = 26/65 (40.00%), Postives = 39/65 (60.00%), Query Frame = 3
Query:  144 MSGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCII 338
            M+ + + K  V QL+ E  + R  VS   +E+ +Y+    D+D LV G   +K NPF+EKGGC+I
Sbjct:    9 MTDLDKAKMEVTQLKTEVKLERAKVSKCCEEITEYIQGGADEDPLVKGIPEEK-NPFKEKGGCVI 72          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Zebrafish
Match: gngt1 (guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 [Source:ZFIN;Acc:ZDB-GENE-030131-7596])

HSP 1 Score: 51.9878 bits (123), Expect = 6.083e-9
Identity = 26/65 (40.00%), Postives = 39/65 (60.00%), Query Frame = 3
Query:  144 MSGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCII 338
            M+ + + K  V QL+ E  + R  VS   +E+ +Y+    D+D LV G   +K NPF+EKGGC+I
Sbjct:    9 MTDLDKAKMEVTQLKTEVKLERAKVSKCCEEITEYIQGGADEDPLVKGIPEEK-NPFKEKGGCVI 72          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Xenopus
Match: gngt2 (guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 [Source:NCBI gene;Acc:100124867])

HSP 1 Score: 52.7582 bits (125), Expect = 4.002e-9
Identity = 24/55 (43.64%), Postives = 35/55 (63.64%), Query Frame = 3
Query:  174 VEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCII 338
            VEQL+ E    R P+S S+ EM  Y++ +  +D L+ G  + + NPF+EKGGC I
Sbjct:   15 VEQLKKEVKTERAPISTSLSEMKTYIESHATEDPLIKGVPDDR-NPFKEKGGCSI 68          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Xenopus
Match: mccc2 (methylcrotonoyl-CoA carboxylase 2 [Source:Xenbase;Acc:XB-GENE-985830])

HSP 1 Score: 50.447 bits (119), Expect = 2.801e-8
Identity = 25/65 (38.46%), Postives = 42/65 (64.62%), Query Frame = 3
Query:  147 SGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
            + I+Q ++ V+QL+ EA+I R  VS +  ++++Y DE+   D L+ G     +NPF++K  CIIL
Sbjct:    9 NNIAQARRTVQQLKVEASIERVKVSKASADLMRYCDEHAKNDPLLMGIP-ASENPFKDKKPCIIL 72          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Xenopus
Match: hsd11b2 (hydroxysteroid (11-beta) dehydrogenase 2 [Source:Xenbase;Acc:XB-GENE-1012826])

HSP 1 Score: 50.447 bits (119), Expect = 3.507e-8
Identity = 26/55 (47.27%), Postives = 34/55 (61.82%), Query Frame = 3
Query:  174 VEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCII 338
            VEQLR E    R  VS S+ E+  Y++ +  +D LV G    K NPF+EKGGC+I
Sbjct:   15 VEQLRKEVKTERIMVSKSIPEIKSYIESHMSEDPLVKGVPEDK-NPFKEKGGCLI 68          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Xenopus
Match: gng7 (guanine nucleotide binding protein (G protein), gamma 7 [Source:NCBI gene;Acc:549887])

HSP 1 Score: 49.6766 bits (117), Expect = 6.253e-8
Identity = 26/65 (40.00%), Postives = 40/65 (61.54%), Query Frame = 3
Query:  147 SGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
            + I+Q +KLVEQLR EA I R  VS +  +++ Y +++   D L+ G     +NPF++K  C IL
Sbjct:    5 NNIAQARKLVEQLRLEAGIERIKVSKAAADLMNYCEQHAKNDPLLVGVPT-SENPFKDKKPCSIL 68          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Xenopus
Match: mgat5 (alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase [Source:Xenbase;Acc:XB-GENE-995554])

HSP 1 Score: 48.1358 bits (113), Expect = 2.027e-7
Identity = 24/55 (43.64%), Postives = 35/55 (63.64%), Query Frame = 3
Query:  174 VEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCII 338
            VEQL+ E  + R+ VS   +E+  Y+++   +D LV G    K NPF+EKGGC+I
Sbjct:   19 VEQLKKEVKLERQLVSKMCEEIKTYIEDKSGEDPLVKGIPEDK-NPFKEKGGCVI 72          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Mouse
Match: Gng12 (guanine nucleotide binding protein (G protein), gamma 12 [Source:MGI Symbol;Acc:MGI:1336171])

HSP 1 Score: 50.447 bits (119), Expect = 2.121e-8
Identity = 25/64 (39.06%), Postives = 40/64 (62.50%), Query Frame = 3
Query:  150 GISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
             I+Q ++ V+QLR EA+I R  VS +  +++ Y +E+   D L+ G     +NPF++K  CIIL
Sbjct:   10 SIAQARRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLMGIPTS-ENPFKDKKTCIIL 72          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Mouse
Match: Gng12 (guanine nucleotide binding protein (G protein), gamma 12 [Source:MGI Symbol;Acc:MGI:1336171])

HSP 1 Score: 50.447 bits (119), Expect = 2.121e-8
Identity = 25/64 (39.06%), Postives = 40/64 (62.50%), Query Frame = 3
Query:  150 GISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
             I+Q ++ V+QLR EA+I R  VS +  +++ Y +E+   D L+ G     +NPF++K  CIIL
Sbjct:   10 SIAQARRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLMGIPTS-ENPFKDKKTCIIL 72          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Mouse
Match: Gng12 (guanine nucleotide binding protein (G protein), gamma 12 [Source:MGI Symbol;Acc:MGI:1336171])

HSP 1 Score: 50.447 bits (119), Expect = 2.121e-8
Identity = 25/64 (39.06%), Postives = 40/64 (62.50%), Query Frame = 3
Query:  150 GISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
             I+Q ++ V+QLR EA+I R  VS +  +++ Y +E+   D L+ G     +NPF++K  CIIL
Sbjct:   10 SIAQARRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLMGIPTS-ENPFKDKKTCIIL 72          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Mouse
Match: Gng12 (guanine nucleotide binding protein (G protein), gamma 12 [Source:MGI Symbol;Acc:MGI:1336171])

HSP 1 Score: 50.447 bits (119), Expect = 2.121e-8
Identity = 25/64 (39.06%), Postives = 40/64 (62.50%), Query Frame = 3
Query:  150 GISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
             I+Q ++ V+QLR EA+I R  VS +  +++ Y +E+   D L+ G     +NPF++K  CIIL
Sbjct:   10 SIAQARRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLMGIPTS-ENPFKDKKTCIIL 72          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Mouse
Match: Gng12 (guanine nucleotide binding protein (G protein), gamma 12 [Source:MGI Symbol;Acc:MGI:1336171])

HSP 1 Score: 50.447 bits (119), Expect = 2.121e-8
Identity = 25/64 (39.06%), Postives = 40/64 (62.50%), Query Frame = 3
Query:  150 GISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
             I+Q ++ V+QLR EA+I R  VS +  +++ Y +E+   D L+ G     +NPF++K  CIIL
Sbjct:   10 SIAQARRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLMGIPTS-ENPFKDKKTCIIL 72          
BLAST of G-protein, gamma subunit,domain-containing protein vs. UniProt/SwissProt
Match: sp|P38040|GBG1_DROME (Guanine nucleotide-binding protein subunit gamma-1 OS=Drosophila melanogaster OX=7227 GN=Ggamma1 PE=2 SV=1)

HSP 1 Score: 70.8626 bits (172), Expect = 3.516e-15
Identity = 30/65 (46.15%), Postives = 49/65 (75.38%), Query Frame = 3
Query:  147 SGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
            S + QQ+ +VEQLR EAAI+R+ +S S  +M++Y+ E++ +D L++GF ++K NPF+EK  C +L
Sbjct:    6 SSLQQQRVVVEQLRREAAIDRQTISESCAKMMKYITEHEQEDYLLTGFTSQKVNPFREKSSCTVL 70          
BLAST of G-protein, gamma subunit,domain-containing protein vs. UniProt/SwissProt
Match: sp|P43425|GBG7_RAT (Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 OS=Rattus norvegicus OX=10116 GN=Gng7 PE=2 SV=2)

HSP 1 Score: 52.7582 bits (125), Expect = 2.028e-8
Identity = 30/69 (43.48%), Postives = 43/69 (62.32%), Query Frame = 3
Query:  144 MSG---ISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
            MSG   ++Q +KLVEQLR EA I R  VS +  E++ Y +++   D L+ G     +NPF++K  CIIL
Sbjct:    1 MSGTNNVAQARKLVEQLRIEAGIERIKVSKASSELMSYCEQHARNDPLLVGVP-ASENPFKDKKPCIIL 68          
BLAST of G-protein, gamma subunit,domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9NFZ3|GBGE_DROME (Guanine nucleotide-binding protein subunit gamma-e OS=Drosophila melanogaster OX=7227 GN=Ggamma30A PE=1 SV=1)

HSP 1 Score: 52.7582 bits (125), Expect = 2.078e-8
Identity = 23/59 (38.98%), Postives = 42/59 (71.19%), Query Frame = 3
Query:  165 KKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
            KK +E ++ +A++ R P+S S+ EM  +++EN+  D L++   +KK+NP+ EKG C+I+
Sbjct:   15 KKQIENMKYQASMERWPLSKSIAEMRSFIEENEKNDPLINA-PDKKNNPWAEKGKCVIM 72          
BLAST of G-protein, gamma subunit,domain-containing protein vs. UniProt/SwissProt
Match: sp|P30671|GBG7_BOVIN (Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 OS=Bos taurus OX=9913 GN=GNG7 PE=1 SV=1)

HSP 1 Score: 52.7582 bits (125), Expect = 2.542e-8
Identity = 28/65 (43.08%), Postives = 41/65 (63.08%), Query Frame = 3
Query:  147 SGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
            + I+Q +KLVEQLR EA I R  VS +  E++ Y +++   D L+ G     +NPF++K  CIIL
Sbjct:    5 NNIAQARKLVEQLRIEAGIERIKVSKASSELMSYCEQHARNDPLLVGVP-ASENPFKDKKPCIIL 68          
BLAST of G-protein, gamma subunit,domain-containing protein vs. UniProt/SwissProt
Match: sp|O60262|GBG7_HUMAN (Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 OS=Homo sapiens OX=9606 GN=GNG7 PE=1 SV=1)

HSP 1 Score: 51.6026 bits (122), Expect = 5.157e-8
Identity = 27/65 (41.54%), Postives = 41/65 (63.08%), Query Frame = 3
Query:  147 SGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
            + I+Q +KLVEQLR EA I R  VS +  +++ Y +++   D L+ G     +NPF++K  CIIL
Sbjct:    5 NNIAQARKLVEQLRIEAGIERIKVSKAASDLMSYCEQHARNDPLLVGVP-ASENPFKDKKPCIIL 68          
BLAST of G-protein, gamma subunit,domain-containing protein vs. TrEMBL
Match: Q8IT61 (Guanine nucleotide-binding protein subunit gamma; Trimeric G-protein gamma subunit OS=Schistosoma mansoni OX=6183 PE=2 SV=1)

HSP 1 Score: 111.694 bits (278), Expect = 1.288e-28
Identity = 50/66 (75.76%), Postives = 60/66 (90.91%), Query Frame = 3
Query:  144 MSGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
            MS +SQQ+KLVEQLR EA +NRRPVS  VQEMI YM++N+DKDCLVSGFA+KKDNPFQEKGGC+++
Sbjct:    1 MSTLSQQRKLVEQLRQEANLNRRPVSECVQEMIVYMEQNRDKDCLVSGFASKKDNPFQEKGGCVVI 66          
BLAST of G-protein, gamma subunit,domain-containing protein vs. TrEMBL
Match: A0A183JX55 (G protein gamma domain-containing protein OS=Schistosoma curassoni OX=6186 GN=SCUD_LOCUS7300 PE=4 SV=1)

HSP 1 Score: 110.538 bits (275), Expect = 4.771e-28
Identity = 49/66 (74.24%), Postives = 60/66 (90.91%), Query Frame = 3
Query:  144 MSGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
            MS +SQQ+KLVEQLR EA +NRRPVS  VQEMI YM++N++KDCLVSGFA+KKDNPFQEKGGC+++
Sbjct:    1 MSTLSQQRKLVEQLRQEANLNRRPVSECVQEMIVYMEQNREKDCLVSGFASKKDNPFQEKGGCVVI 66          
BLAST of G-protein, gamma subunit,domain-containing protein vs. TrEMBL
Match: A0A183N8Z7 (G protein gamma domain-containing protein OS=Schistosoma margrebowiei OX=48269 GN=SMRZ_LOCUS24772 PE=4 SV=1)

HSP 1 Score: 110.538 bits (275), Expect = 4.771e-28
Identity = 49/66 (74.24%), Postives = 60/66 (90.91%), Query Frame = 3
Query:  144 MSGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
            MS +SQQ+KLVEQLR EA +NRRPVS  VQEMI YM++N++KDCLVSGFA+KKDNPFQEKGGC+++
Sbjct:    1 MSTLSQQRKLVEQLRQEANLNRRPVSECVQEMIVYMEQNREKDCLVSGFASKKDNPFQEKGGCVVI 66          
BLAST of G-protein, gamma subunit,domain-containing protein vs. TrEMBL
Match: A0A183WBU9 (G protein gamma domain-containing protein OS=Trichobilharzia regenti OX=157069 GN=TRE_LOCUS9602 PE=4 SV=1)

HSP 1 Score: 110.153 bits (274), Expect = 5.259e-28
Identity = 50/66 (75.76%), Postives = 59/66 (89.39%), Query Frame = 3
Query:  144 MSGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
            MS +SQQ+KLVEQLR EA INRRPVS  VQ+MI YM++N+DKDCLVSGFA+KKDNPFQEKGGC ++
Sbjct:    1 MSTLSQQRKLVEQLRQEANINRRPVSECVQDMIVYMEQNRDKDCLVSGFASKKDNPFQEKGGCTVI 66          
BLAST of G-protein, gamma subunit,domain-containing protein vs. TrEMBL
Match: G4M241 (G protein gamma domain-containing protein OS=Schistosoma mansoni OX=6183 GN=Smp_205760 PE=4 SV=1)

HSP 1 Score: 110.153 bits (274), Expect = 7.044e-28
Identity = 49/66 (74.24%), Postives = 59/66 (89.39%), Query Frame = 3
Query:  144 MSGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
            MS +SQQ+KLVEQLR EA +NRRPVS  VQEMI YM++N+DKDCL SGFA+KKDNPFQEKGGC+++
Sbjct:    1 MSTLSQQRKLVEQLRQEANLNRRPVSECVQEMIVYMEQNRDKDCLFSGFASKKDNPFQEKGGCVVI 66          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Cavefish
Match: gng7 (guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 [Source:NCBI gene;Acc:103035574])

HSP 1 Score: 51.9878 bits (123), Expect = 4.086e-9
Identity = 26/65 (40.00%), Postives = 41/65 (63.08%), Query Frame = 3
Query:  147 SGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
            + I+Q +KLVEQLR EA I R  VS +  +++ Y +++   D L+ G     +NPF++K  CI+L
Sbjct:    5 NNIAQARKLVEQLRIEAGIERIKVSKAAADLMSYCEQHARSDALLVGVPT-SENPFKDKKPCILL 68          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Cavefish
Match: gngt1 (guanine nucleotide-binding protein G(T) subunit gamma-T1 [Source:NCBI gene;Acc:103023645])

HSP 1 Score: 51.2174 bits (121), Expect = 1.045e-8
Identity = 24/65 (36.92%), Postives = 41/65 (63.08%), Query Frame = 3
Query:  144 MSGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCII 338
            ++ + + K  V QL+ E  + R  VS   +E+++Y+    ++D LV G + +K NPF+EKGGC+I
Sbjct:    9 LTDLDKAKMEVTQLKVEVKLEREKVSKCCEEVMEYIQAGVEEDILVKGISEEK-NPFKEKGGCVI 72          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Cavefish
Match: gngt1 (guanine nucleotide-binding protein G(T) subunit gamma-T1 [Source:NCBI gene;Acc:103023645])

HSP 1 Score: 51.2174 bits (121), Expect = 1.045e-8
Identity = 24/65 (36.92%), Postives = 41/65 (63.08%), Query Frame = 3
Query:  144 MSGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCII 338
            ++ + + K  V QL+ E  + R  VS   +E+++Y+    ++D LV G + +K NPF+EKGGC+I
Sbjct:    9 LTDLDKAKMEVTQLKVEVKLEREKVSKCCEEVMEYIQAGVEEDILVKGISEEK-NPFKEKGGCVI 72          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Cavefish
Match: gngt2b (guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 [Source:NCBI gene;Acc:103025140])

HSP 1 Score: 49.6766 bits (117), Expect = 3.656e-8
Identity = 24/55 (43.64%), Postives = 35/55 (63.64%), Query Frame = 3
Query:  174 VEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCII 338
            ++QL+ E   +R  VSA+  ++I Y++    +D LV G    K NPF+EKGGCII
Sbjct:   15 LDQLKIEVKTSRTAVSATAPDIISYVEARSGEDPLVKGVPEDK-NPFKEKGGCII 68          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Cavefish
Match: gng12a (guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 [Source:NCBI gene;Acc:107196998])

HSP 1 Score: 49.2914 bits (116), Expect = 6.613e-8
Identity = 24/63 (38.10%), Postives = 40/63 (63.49%), Query Frame = 3
Query:  153 ISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
            ++Q ++ V+QLR EA I R  VS +  ++++Y  E+   D L++G     +NPF++K  CIIL
Sbjct:   15 LAQARRTVQQLRVEAGIERIKVSKASADLMRYCSEHAKYDPLLTGIP-ASENPFKDKKPCIIL 76          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Sea Lamprey
Match: gngt2b (guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2b [Source:ZFIN;Acc:ZDB-GENE-091020-4])

HSP 1 Score: 45.8246 bits (107), Expect = 1.856e-7
Identity = 22/54 (40.74%), Postives = 32/54 (59.26%), Query Frame = 3
Query:  177 EQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCII 338
            EQLR E  + R  +S    +++ +++ N   D LV G    K NPF+EKGGC+I
Sbjct:   17 EQLRIEVKLTREKISKVAPDILAHVESNMADDPLVKGVPEDK-NPFKEKGGCVI 69          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Nematostella
Match: EDO48385 (Guanine nucleotide-binding protein subunit gamma [Source:UniProtKB/TrEMBL;Acc:A7RJI5])

HSP 1 Score: 45.0542 bits (105), Expect = 5.330e-7
Identity = 24/62 (38.71%), Postives = 35/62 (56.45%), Query Frame = 3
Query:  156 SQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
            SQ  K VE L+ +  I R PVS    ++  Y  +N++ D L+    +KKDNP+ EK  C +L
Sbjct:    4 SQLMKTVESLKYQLQIQRMPVSKCSNDLKSYCTQNQEHDPLICP-PDKKDNPWAEKTKCTVL 64          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Nematostella
Match: EDO36536 (Guanine nucleotide-binding protein subunit gamma [Source:UniProtKB/TrEMBL;Acc:A7SI97])

HSP 1 Score: 42.3578 bits (98), Expect = 5.250e-6
Identity = 23/63 (36.51%), Postives = 37/63 (58.73%), Query Frame = 3
Query:  153 ISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
            IS Q+ +V+QLR E  + R  VS +  E++++ + +  +D LV G     DNPF+EK  C + 
Sbjct:    8 ISTQRAVVDQLRGELKVTRMKVSQTSVELMKFCENHCAEDPLVHGLP-PGDNPFREKTSCTLF 69          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Medaka
Match: si:dkey-117i10.1 (guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12-like [Source:NCBI gene;Acc:110015484])

HSP 1 Score: 53.5286 bits (127), Expect = 1.411e-9
Identity = 26/64 (40.62%), Postives = 41/64 (64.06%), Query Frame = 3
Query:  150 GISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
             + Q +KLVEQLR EA++ R  +S +  +++QY  E++  D L+ G A    NPF+EK  C++L
Sbjct:   12 SVIQAQKLVEQLRLEASMVRFKISLTAADLVQYCQEHRCSDPLLMGIA-ASSNPFKEKKTCVLL 74          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Medaka
Match: gngt1 (guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 [Source:ZFIN;Acc:ZDB-GENE-030131-7596])

HSP 1 Score: 49.6766 bits (117), Expect = 3.498e-8
Identity = 24/55 (43.64%), Postives = 35/55 (63.64%), Query Frame = 3
Query:  174 VEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCII 338
            V QL+ E  + R   S   +EM +Y+ E  ++D LV G + +K NPF+EKGGC+I
Sbjct:   19 VNQLKLEVKLERWLTSKCCEEMKEYIQERVEEDTLVKGISEEK-NPFKEKGGCVI 72          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Medaka
Match: gng5 (guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 [Source:NCBI gene;Acc:110016922])

HSP 1 Score: 46.9802 bits (110), Expect = 3.388e-7
Identity = 26/65 (40.00%), Postives = 39/65 (60.00%), Query Frame = 3
Query:  147 SGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
            S I   KK+V+QLR EA+INR  VS +  E+ Q+   N  +D L++G ++   NPF+ +  C  L
Sbjct:    5 SSIVAMKKVVQQLRYEASINRVKVSQAAAELQQFCMNNATQDPLLTGMSS-STNPFRPQKVCSFL 68          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Medaka
Match: GNG5 (G protein subunit gamma 5 [Source:NCBI gene;Acc:111947358])

HSP 1 Score: 45.4394 bits (106), Expect = 1.280e-6
Identity = 23/65 (35.38%), Postives = 40/65 (61.54%), Query Frame = 3
Query:  147 SGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
            + I   KK+++QLR EA+INR  VS +  ++ Q+  +N   D L++G ++  +NPF+ +  C  L
Sbjct:    3 ANIVTMKKIIQQLRLEASINRVKVSQAATDLQQFCLQNAQHDPLLTGMSS-SNNPFRPQKVCSFL 66          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Medaka
Match: gng2 (G protein subunit gamma 2 [Source:NCBI gene;Acc:101157742])

HSP 1 Score: 44.669 bits (104), Expect = 2.875e-6
Identity = 27/66 (40.91%), Postives = 41/66 (62.12%), Query Frame = 3
Query:  147 SGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKG-GCIIL 341
            + I+Q +KLVEQL+ EA I+R  VS +  E++ Y + +  +D L+S      +NPF+EK   C IL
Sbjct:   14 ASIAQARKLVEQLKMEANIDRIKVSKAAAELMSYCEAHAKEDPLLSPVP-ASENPFREKKFFCSIL 78          
BLAST of G-protein, gamma subunit,domain-containing protein vs. Planmine SMEST
Match: SMESG000066557.1 (SMESG000066557.1)

HSP 1 Score: 136.732 bits (343), Expect = 7.021e-42
Identity = 66/66 (100.00%), Postives = 66/66 (100.00%), Query Frame = 3
Query:  144 MSGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 341
            MSGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL
Sbjct:    1 MSGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGGCIIL 66          
The following BLAST results are available for this feature:
BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
GNG71.074e-841.54G protein subunit gamma 7 [Source:HGNC Symbol;Acc:... [more]
GNG125.877e-839.06G protein subunit gamma 12 [Source:HGNC Symbol;Acc... [more]
GNG111.459e-745.45G protein subunit gamma 11 [Source:HGNC Symbol;Acc... [more]
GNGT24.549e-640.00G protein subunit gamma transducin 2 [Source:HGNC ... [more]
GNGT24.549e-640.00G protein subunit gamma transducin 2 [Source:HGNC ... [more]
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BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3
Match NameE-valueIdentityDescription
gpc-13.577e-845.76Guanine nucleotide-binding protein subunit gamma ... [more]
gpc-13.577e-845.76Guanine nucleotide-binding protein subunit gamma ... [more]
gpc-13.577e-845.76Guanine nucleotide-binding protein subunit gamma ... [more]
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BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ggamma13.508e-1646.15gene:FBgn0004921 transcript:FBtr0088645[more]
Ggamma13.508e-1646.15gene:FBgn0004921 transcript:FBtr0088647[more]
Ggamma13.508e-1646.15gene:FBgn0004921 transcript:FBtr0088646[more]
CG433249.611e-1344.62gene:FBgn0263029 transcript:FBtr0306907[more]
Ggamma30A1.676e-938.98gene:FBgn0267252 transcript:FBtr0336620[more]
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BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
si:dkey-117i10.12.650e-935.29si:dkey-117i10.1 [Source:ZFIN;Acc:ZDB-GENE-091204-... [more]
gng73.887e-942.86guanine nucleotide binding protein (G protein), ga... [more]
gng73.887e-942.86guanine nucleotide binding protein (G protein), ga... [more]
gngt16.083e-940.00guanine nucleotide binding protein (G protein), ga... [more]
gngt16.083e-940.00guanine nucleotide binding protein (G protein), ga... [more]
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BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
gngt24.002e-943.64guanine nucleotide binding protein (G protein), ga... [more]
mccc22.801e-838.46methylcrotonoyl-CoA carboxylase 2 [Source:Xenbase;... [more]
hsd11b23.507e-847.27hydroxysteroid (11-beta) dehydrogenase 2 [Source:X... [more]
gng76.253e-840.00guanine nucleotide binding protein (G protein), ga... [more]
mgat52.027e-743.64alpha-1,6-mannosylglycoprotein 6-beta-N-acetylgluc... [more]
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BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Gng122.121e-839.06guanine nucleotide binding protein (G protein), ga... [more]
Gng122.121e-839.06guanine nucleotide binding protein (G protein), ga... [more]
Gng122.121e-839.06guanine nucleotide binding protein (G protein), ga... [more]
Gng122.121e-839.06guanine nucleotide binding protein (G protein), ga... [more]
Gng122.121e-839.06guanine nucleotide binding protein (G protein), ga... [more]
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BLAST of G-protein, gamma subunit,domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P38040|GBG1_DROME3.516e-1546.15Guanine nucleotide-binding protein subunit gamma-1... [more]
sp|P43425|GBG7_RAT2.028e-843.48Guanine nucleotide-binding protein G(I)/G(S)/G(O) ... [more]
sp|Q9NFZ3|GBGE_DROME2.078e-838.98Guanine nucleotide-binding protein subunit gamma-e... [more]
sp|P30671|GBG7_BOVIN2.542e-843.08Guanine nucleotide-binding protein G(I)/G(S)/G(O) ... [more]
sp|O60262|GBG7_HUMAN5.157e-841.54Guanine nucleotide-binding protein G(I)/G(S)/G(O) ... [more]
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BLAST of G-protein, gamma subunit,domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
Q8IT611.288e-2875.76Guanine nucleotide-binding protein subunit gamma; ... [more]
A0A183JX554.771e-2874.24G protein gamma domain-containing protein OS=Schis... [more]
A0A183N8Z74.771e-2874.24G protein gamma domain-containing protein OS=Schis... [more]
A0A183WBU95.259e-2875.76G protein gamma domain-containing protein OS=Trich... [more]
G4M2417.044e-2874.24G protein gamma domain-containing protein OS=Schis... [more]
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BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
gng74.086e-940.00guanine nucleotide-binding protein G(I)/G(S)/G(O) ... [more]
gngt11.045e-836.92guanine nucleotide-binding protein G(T) subunit ga... [more]
gngt11.045e-836.92guanine nucleotide-binding protein G(T) subunit ga... [more]
gngt2b3.656e-843.64guanine nucleotide-binding protein G(I)/G(S)/G(O) ... [more]
gng12a6.613e-838.10guanine nucleotide-binding protein G(I)/G(S)/G(O) ... [more]
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BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
gngt2b1.856e-740.74guanine nucleotide binding protein (G protein), ga... [more]
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BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO483855.330e-738.71Guanine nucleotide-binding protein subunit gamma ... [more]
EDO365365.250e-636.51Guanine nucleotide-binding protein subunit gamma ... [more]
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BLAST of G-protein, gamma subunit,domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
si:dkey-117i10.11.411e-940.63guanine nucleotide-binding protein G(I)/G(S)/G(O) ... [more]
gngt13.498e-843.64guanine nucleotide binding protein (G protein), ga... [more]
gng53.388e-740.00guanine nucleotide-binding protein G(I)/G(S)/G(O) ... [more]
GNG51.280e-635.38G protein subunit gamma 5 [Source:NCBI gene;Acc:11... [more]
gng22.875e-640.91G protein subunit gamma 2 [Source:NCBI gene;Acc:10... [more]
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BLAST of G-protein, gamma subunit,domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000066557.17.021e-42100.00SMESG000066557.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30020678 ID=SMED30020678|Name=G-protein, gamma subunit,domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=657bp
TCTTACAAATTGTTCTTACTTACACTTAATCCTGCATAATTAATTCAACA
ATTCAATTTTAGATCAATACTTTATAAATTATTTAATTATAATTTATCAT
CAGTTTTGCTATAATTCTATATTATCACATTAAAAATTATTAAATGTCTG
GAATTAGTCAACAGAAAAAACTAGTCGAACAATTACGAGCAGAAGCTGCA
ATTAACCGGAGACCAGTTTCAGCCAGTGTTCAAGAAATGATTCAATACAT
GGATGAAAACAAAGATAAAGACTGTTTAGTAAGTGGGTTTGCTAACAAAA
AGGACAATCCTTTCCAAGAAAAAGGTGGATGTATTATTTTATAGAACATC
TTTAACTCTCTTTTTGAAAATGAGCAGACATTGTTTATGATAGTGCAATT
AGATTTTGTATAATTTATGGTATACTAAATAGCACTTTGTTTTTACATGT
TAATTGTTCAATTTTTAGCACAGAATATCAGAATATATATATATTAAATT
TCGAAAGTGATCACAATTTCTGGTTATTACAAATCCATTTGCCAATGTTG
GCTGAAATGTTGTATTTATTAAACGAATTTAATACATAATTATTTAATTG
TAGTATAGTAAATATTCCATTTTTGTGTACAAACTATTAATAAATTGTTA
TTATTTA
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Aliases
The feature 'G-protein, gamma subunit,domain-containing protein' has the following synonyms
Synonym
gnc
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0003924GTPase activity
GO:0004871signal transducer activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000017photoreceptor neuron
PLANA:0000020protonephridia
PLANA:0000099neuron
PLANA:0000101muscle cell
PLANA:0000418head
PLANA:0000463cholinergic neuron
PLANA:0000464GABAergic neuron
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR036284GGL_sf
IPR001770Gprotein-gamma
IPR015898G-protein_gamma-like_dom
Vocabulary: biological process
TermDefinition
GO:0007186G-protein coupled receptor signaling pathway
GO:0007165signal transduction
Vocabulary: cellular component
TermDefinition
GO:0005834heterotrimeric G-protein complex
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR015898G-protein gamma-like domainSMARTSM00224GGL_4coord: 4..66
e-value: 1.9E-17
score: 73.9
IPR015898G-protein gamma-like domainPFAMPF00631G-gammacoord: 6..66
e-value: 4.4E-14
score: 52.2
IPR015898G-protein gamma-like domainPROSITEPS50058G_PROTEIN_GAMMAcoord: 1..66
score: 21.904
IPR015898G-protein gamma-like domainCDDcd00068GGLcoord: 4..61
e-value: 3.61707E-15
score: 60.3806
NoneNo IPR availableSMARTSM01224G_gamma_2coord: 1..66
e-value: 2.8E-17
score: 73.4
NoneNo IPR availablePANTHERPTHR13809:SF48GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT GAMMA-RELATEDcoord: 1..66
IPR036284G-protein gamma-like domain superfamilyGENE3DG3DSA:4.10.260.10coord: 1..66
e-value: 3.9E-23
score: 83.1
IPR036284G-protein gamma-like domain superfamilySUPERFAMILYSSF48670Transducin (heterotrimeric G protein), gamma chaincoord: 2..61
IPR001770G-protein, gamma subunitPANTHERPTHR13809GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNITcoord: 1..66