Protein HIRA

Query:   25 MRIVKPIYINYQNPQKDQILTEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIW----------VQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDK-NSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKETKEE-------FLLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELGIPLTLDEMKQFFEKTYGSGFVVDNSAISKSKNNAFIIPESSAVLKXXXXXXXXNHDRKSTSLHLLNE----------------KKTGPNEQIICHTKTGKRRITPKFLSSLDDEDI 1395
            M+++KP ++N+           I S+DIHP G KFAT G G   G + IWNM P+  ++ E DEN PK+L     HL CVNCVRWS +G YLASG  D ++++W          V      L ++     E +R    LR HS D++D+AWSPH  +L S SVDN ++IWN  KFPE  A L GH+  +KG+ WDPVG+Y+ASQ++D +L++WRT DW+ ET +    D+   +    RL+WSPDG  +V+    NN  PT Q+  R+ W   +D VGH++ +   ++ P + + K+           +   A+GSKDRSLSVW T  +RPLVVI +LF  SI+D+SW +    ++ CS+DGS+A++ F+ DELG PL+ +E  +  + TYG    +    +++++ +  +I E+  +LK Q++QQ    D+KS +   +                  +K    +Q+   T  G+RRITP  ++ LD  D 
Sbjct:    1 MKLLKPTWVNHNG-------KPIFSVDIHPDGTKFATGGQGQDSGKVVIWNMSPVLQEDDEKDENIPKMLCQMDNHLACVNCVRWSNSGMYLASGGDDKLIMVWKRATYIGPSTVFGSSGKLANV-----EQWRCVSILRNHSGDVMDVAWSPHDAWLASCSVDNTVVIWNAVKFPEILATLRGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTLDWQLETSITKPFDECGGTTHVLRLSWSPDGHYLVSAHAMNNSGPTAQIIEREGWKTNMDFVGHRKAVTVVKFNPKIFKKKQKNGSSAKPSCPYCCCAVGSKDRSLSVWLTCLKRPLVVIHELFDKSIMDISWTLNGLGILVCSMDGSVAFLDFSQDELGDPLSEEEKSRIHQSTYGKSLAI----MTEAQLSTAVI-ENPEMLKYQRRQQQQQLDQKSAATREMGSATSVAGVVNGESLEDIRKNLLKKQVETRTADGRRRITPLCIAQLDTGDF 474          

Query: 2437 IFLKESFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSNK----SEFWSVSKLSSKNLINKPLASMQSSESICDGPMKNLSSI---VKQELILDRLEIQVKLAESLHSCEEYKYWLLLWVRHLIEADKEVRVRDICQRFLGPIHTSTKSNWDPFILRYSKRELLKEILPLFALNLRLQRLYT 3018
            + +KE  +H +    D T +  I ++  G   +    G ++ FN  ++ W  V +  +     ++F S        L + PLA +Q   S        L S+   V+QE  L  LE QV  A +L S  EY++WLL++ R+L+    E R+R+IC+  LGP+H ST S W+  ++   KRELLKE+LP+   NLR QRL+T
Sbjct:  599 VVVKEESLHSILAGSDMT-VSQILLTQHGIPVMNLSDGKAYCFNPSLSTWNLVSDKQDSLAQCADFRSSLPSQDAMLCSGPLAIIQGRTSNSGRQAARLFSVPHVVQQETTLAYLENQVAAALTLQSSHEYRHWLLVYARYLVNEGFEYRLREICKDLLGPVHYSTGSQWESTVVGLRKRELLKELLPVIGQNLRFQRLFT 798          

Query:   25 MRIVKPIYINYQNPQKDQILTEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHI---DKKFH--ESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDK-NSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKETKEE-------FLLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELGIPLTLDEMKQFFEKTYGSGFVVDNSAISKSKNNAFIIPESSAVLKXXXXXXXXNHDRKSTSLHLLNE----------------KKTGPNEQIICHTKTGKRRITPKFLSSLDDED 1392
            M+++KP ++N+           I S+DIHP G KFAT G G   G + IWNM P+  ++ E DEN PK+L     HL CVNCVRWS +G YLASG  D ++++W +        +     K    E +R    LR HS D++D+AWSPH  +L S SVDN ++IWN  KFPE  A L GH+  +KG+ WDPVG+Y+ASQ++D +L++WRT DW+ ET +    D+   +    RL+WSPDG  +V+    NN  PT Q+  R+ W   +D VGH++ +   ++ P + + K+           +   A+GSKDRSLSVW T  +RPLVVI +LF  SI+D+SW +    ++ CS+DGS+A++ F+ DELG PL+ +E  +  + TYG    +    +++++ +  +I E+  +LK Q++QQ    D+KS +   +                  +K    +Q+   T  G+RRITP  ++ LD  D
Sbjct:    1 MKLLKPTWVNHNG-------KPIFSVDIHPDGTKFATGGQGQDSGKVVIWNMSPVLQEDDEKDENIPKMLCQMDNHLACVNCVRWSNSGMYLASGGDDKLIMVWKRATYIGPSTVFGSSGKLANVEQWRCVSILRNHSGDVMDVAWSPHDAWLASCSVDNTVVIWNAVKFPEILATLRGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTLDWQLETSITKPFDECGGTTHVLRLSWSPDGHYLVSAHAMNNSGPTAQIIEREGWKTNMDFVGHRKAVTVVKFNPKIFKKKQKNGSSAKPSCPYCCCAVGSKDRSLSVWLTCLKRPLVVIHELFDKSIMDISWTLNGLGILVCSMDGSVAFLDFSQDELGDPLSEEEKSRIHQSTYGKSLAI----MTEAQLSTAVI-ENPEMLKYQRRQQQQQLDQKSAATREMGSATSVAGVVNGESLEDIRKNLLKKQVETRTADGRRRITPLCIAQLDTGD 473          

Query: 2191 NNDQKLWEITQTKQISVMAHFKDKLFVGDVCGFLHSFYLKGGRIQAPFSLDSGLTSLVCDGRYLIAVTVRATLYIWSIAPFAIFLKESFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSNK----SEFWSVSKLSSKNLINKPLASMQSSESICDGPMKNLSSI---VKQELILDRLEIQVKLAESLHSCEEYKYWLLLWVRHLIEADKEVRVRDICQRFLGPIHTSTKSNWDPFILRYSKRELLKEILPLFALNLRLQRLYT 3018
            N + K WE   T +I   A   D + V      L  F   G R+ +P  L S +++L C G Y++A+T  ATL +W +    + +KE  +H +    D T +  I ++  G   +    G ++ FN  ++ W  V +  +     ++F S        L + PLA +Q   S        L S+   V+QE  L  LE QV  A +L S  EY++WLL++ R+L+    E R+R+IC+  LGP+H ST S W+  ++   KRELLKE+LP+   NLR QRL+T
Sbjct:  724 NREGKEWETVLTSRILTAAGSCDVVCVACEKRMLSVFSTCGRRLLSPILLPSPISTLHCTGSYVMALTAAATLSVWDVHRQVVVVKEESLHSILAGSDMT-VSQILLTQHGIPVMNLSDGKAYCFNPSLSTWNLVSDKQDSLAQCADFRSSLPSQDAMLCSGPLAIIQGRTSNSGRQAARLFSVPHVVQQETTLAYLENQVAAALTLQSSHEYRHWLLVYARYLVNEGFEYRLREICKDLLGPVHYSTGSQWESTVVGLRKRELLKELLPVIGQNLRFQRLFT 1005          

Query:  250 HLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDK-KFH---------ESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQE---TKLCDEI-------------DKNSSCSFQRLTWSPDGSNIVATG----TSNNGAPTCQLYNRDNWSKGVDMV---GHKQHII--CARYFPTLLRSKETKEEF------LLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELGIPL 1104
            H K VN VR+SP G+ LASG  DAV+++W   K+ND +  ++  F          E++     LRGH  D+ D+ W+  G  + S SVDN  IIW+V K  +K +I N H S+++GV WDP+G+Y+A+ S D  LR++     +     +K+   I             D +    F+RL+++PDGS ++       +  N   T  +++R N  + +  +   G     +  C  YF  L    ET  E       L+ A+ S+D S+ ++ T +  P   +S++  +++ D+SW  +   L   S DG  ++V F  DELGIPL
Sbjct:   65 HTKAVNVVRFSPTGEILASGGDDAVILLW---KVNDNKEPEQIAFQDEDEAQLNKENWTVVKTLRGHLEDVYDICWATDGNLMASASVDNTAIIWDVSKG-QKISIFNEHKSYVQGVTWDPLGQYVATLSCDRVLRVYSIQKKRVAFNVSKMLSGIGAEGEARSYRMFHDDSMKSFFRRLSFTPDGSLLLTPAGCVESGENVMNTTYVFSRKNLKRPIAHLPCPGKATLAVRCCPVYF-ELRPVVETGVELMSLPYRLVFAVASED-SVLLYDTQQSFPFGYVSNIHYHTLSDISWSSDGAFLAISSTDGYCSFVTFEKDELGIPL 384          

Query:  250 HLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVG-----RYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDG 729
            H + V  V +SP GKYLASGS D  V  W      DL         +    F  +GH + ++ ++WSP G  L SG  + +I++W+     +    L GH+ +I G+ W+P+      RY+AS S+D ++RIW T+  +     C+ I    + S   L W  DG
Sbjct:  113 HSEAVISVAFSPTGKYLASGSGDTTVRFW------DLS--------TETPHFTCKGHRHWVLSISWSPDGRKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGR-----CERILTGHTQSVTCLRWGGDG 258          

Query:  250 HLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAI-LNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWR 636
            H   +N V +SP+ + +AS S D  + +W  +    L                LRGH   +  +AWS     L SGS D+ + +W+V    +K A+ L GH   +  V W P G+ +AS  +D  LRIWR
Sbjct:  371 HQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLA--------------SLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKA--QKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIWR 484          

Query:  394 RSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVD-KFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSN----IVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKETKEEFLLLALGSKDRSLSVW 942
            R    L GHS  ++ +A+SP G YL SGS D  +  W++  + P  T    GH  ++  + W P GR LAS  ++  + +W  S  KQ  +         S     L+W P  +N     VA+ + +    + ++++         + GH Q + C R+               LL   S+DR++ VW
Sbjct:  105 RCTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTC--KGHRHWVLSISWSPDGRKLASGCKNGQILLWDPSTGKQVGRTL----AGHSKWITGLSWEPLHANPECRYVASSSKDG---SVRIWDTTAGRCERILTGHTQSVTCLRWGGD-----------GLLYSASQDRTIKVW 272          

Query:   91 ICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSP-HGT----YLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSD 645
            + S+   P+GK  A SG GD    +  W++        ET        +T   H   V  + WSP+G+ LASG  +  +++W       +                L GHS  I  L+W P H      Y+ S S D  + IW+         IL GH   +  + W   G  L S S+D T+++WR  D
Sbjct:  117 VISVAFSPTGKYLA-SGSGDT--TVRFWDL------STETPH------FTCKGHRHWVLSISWSPDGRKLASGCKNGQILLWDPSTGKQVGRT-------------LAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTA-GRCERILTGHTQSVTCLRWGGDG-LLYSASQDRTIKVWRAHD 276          

Query:  151 KYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFH----ESYRSAFQLRGHSYDIVDLAWSPH---GTY---------------------LCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKETKEEFLLLALGSKDRSLSVW 942
            K G + IW+          T   C +IL     H + V C+RW  +G  L S S D  + +W          +    H     +  + + LR  +++  + + +P    G+                      L SGS D  + +W+  +  +    + GH + I  V + P  R +AS S D ++++W     K    L     +    +  ++ WS D S ++ +G+S++   T ++++       +D+ GH   +    + P   R          +A G KD+ L +W
Sbjct:  224 KDGSVRIWDT---------TAGRCERILTG---HTQSVTCLRWGGDG-LLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASL-----RGHVAAVYQIAWSAD-SRLLVSGSSDS---TLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQR----------VASGGKDKCLRIW 483          

Query:  109 HPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEK--TAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWR 636
            +P+G   A+ GG  +   I IW          E D    K + ++  H + V  V WSP G YLAS S DA   IW            KK  + +     L GH  ++  +AW+P G  L + S D  + +W VD+  E    ++LN H   +K V W P    LAS S D T++++R
Sbjct:   25 NPAGTLLASCGGDRR---IRIWGT--------EGDSWICKSVLSE-GHQRTVRKVAWSPCGNYLASASFDATTCIW------------KKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEEDEYECVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYR 178          

Query:  271 VRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIW--NVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLY--NRDNWSKGVDMVGHKQHIICARYFPTLLRSKETKEEFLLLALGSKDRSLSVWTTL---------------RRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIA 1065
            + W+P G  LAS   D  + IW  +        D    +S  S     GH   +  +AWSP G YL S S D    IW  N D F E    L GH + +K V W P G  LA+ S D ++ +W   +  ++   C  +  + +   + + W P    ++A+ + ++   T +LY    D+W     + GH+  +    + P+  R          LA  S DR++ +W                    + +  +S   + +I D++W         C L G++A
Sbjct:   22 LAWNPAGTLLASCGGDRRIRIWGTEG-------DSWICKSVLS----EGHQRTVRKVAWSPCGNYLASASFDATTCIWKKNQDDF-ECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDE--EDEYECVSVLNSHTQDVKHVVWHP-SQELLASASYDD---TVKLYREEEDDWVCCATLEGHESTVWSLAFDPSGQR----------LASCSDDRTVRIWRQYLPGNEQGVACSGSDPSWKCICTLSGFHSRTIYDIAW---------CQLTGALA 268          

Query:   91 ICSIDIHPSGKKFATSGGGDKY--GIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKL-NDLEHIDKKFH--ESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKN-SSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRS---KETKEEFLLLALGSKDRSLSVWT---TLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELGIPLTLDEMKQFFEKTYG---------------SGFVVDNSAISKSKNNAFII--PESSAVLKXXXXXXXXNHDRKSTSLHLLNEKKTGP-----------NEQIICHTKTGKRRITPKF-----------LSSLDDEDIEPDPAPSKRI 1425
            I +ID HPSGKKF T G   +   G++ +WN +P+ +K+K ++EN PK+L+   +  +  +C RWSP+GK  A GS D+ V +W    L N +  I       E Y+    LRGHS +++ + WSP+G YL SGS+D RIII+N  K P++  +LN     +KG+ WDP+G+YLAS   D  LR W T  W+    + +  + N       RL WSPDG  ++      +G P  +L  R  W     + GH +   C R  P L+ +      + +    A+GS+D+S+S+W    TL  +PL VI+++F ++++D +W      L+ACS DG++  +  ++  +G  ++ + M     + Y                S    + S +S S NNA  +  PE   + + +      + D + T     N K+              N+QI    K GKRRI P F           LSS   + + P PA  K +
Sbjct:   19 ILAIDCHPSGKKFITCGQKARTSNGLVVVWNAEPVLDKKKASNENVPKLLFQVESQSQSNSC-RWSPDGKRFAFGSDDSSVSVWEYVGLINSMGSITGGAQNVERYKECCVLRGHSMEVLTVEWSPNGKYLASGSIDYRIIIYNARKLPDRITVLNDIQLPVKGLSWDPIGKYLASLEGDKKLRFWATDSWQCVKSVTEPFESNIEETMLTRLDWSPDGKYLMTPAAVRSGKPLIKLIQRQTWKSDQFLAGHHKGTTCVRAMPRLIEANLKNGKRMQLTCAAVGSRDKSISIWVFPGTL--KPLFVINNIFNHTVMDFAWCGR--NLLACSQDGTVKVIHLSESVIGEMISNEAMSDLCYQIYSIRPPRYELTDKEEDESQDSFNLSDLSSSANNASFVTCPEDVLIKRKKLVAAQQSSDIQLTKSMEDNSKENESKNSEKTMMEERNKQIDVR-KDGKRRIQPVFCGTTTADPMTSLSSEGKKTVAPPPAKRKAL 508          

Query:   40 PIYINYQNPQKDQILTEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKL 666
            PI    Q+PQ+      +  +  HP+G   AT+         S W M  +  K++        +LY +  H K V  V + P+G    +G  D    +W  +              + R    L GH+ +I  + W P+G  + +GS DN + +W++ +    T  +  H S +  V  D  G+YL S S D TL++W T+ W+   +L
Sbjct:  288 PIGELEQHPQR------VSKVAFHPNGHHLATAC------FDSTWRMYDLTTKKE--------LLYQE-GHSKSVADVAFHPDGSVALTGGHDCYGRVWDMR--------------TGRCIMFLDGHTKEIHSVEWMPNGYEMITGSSDNSMKVWDL-RMRRNTYTMPAHTSVVTRVRADAAGQYLVSASFDCTLKMWSTTGWQPLRQL 460          

Query:   91 ICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDW 648
            +  +  HP G   A +GG D YG   +W+M   R         C  I++ D  H K ++ V W PNG  + +GS D  + +W      DL           R+ + +  H+  +  +     G YL S S D  + +W+   + +    L GH++ I  V   P G+++ S + D T ++W  SD+
Sbjct:  341 VADVAFHPDGS-VALTGGHDCYG--RVWDMRTGR---------C--IMFLD-GHTKEIHSVEWMPNGYEMITGSSDNSMKVW------DLR--------MRRNTYTMPAHTSVVTRVRADAAGQYLVSASFDCTLKMWSTTGW-QPLRQLQGHDTRILCVDISPDGQWMCSSAFDRTFKLWAQSDY 496          

Query:  247 THLKCVNCVRWSPNGKYLASGSVDAVVVIW----VQKK--------LNDL--------------EHIDKKFH-ESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKETKEEFLLLALGSKDRSLSVWTTLRRRPL 966
             H K ++ +++SP+G+Y+ SGS D  + IW    V +K        +N+               + + K F   S R    L+GH+  +    ++P GT + SGS D  I IW   +       + GH   +  VC++  G YLAS S D  +RIW ++       L DE           + +SP+G  I+A+  +N    T +L++        +  GH+    C     ++   K        +  GS+D  + +W    R  L
Sbjct:  105 AHKKSISGIKFSPDGRYMGSGSADCSIKIWRMDFVYEKTLMGHRLGINEFSWSSDSKLIVSCSDDKLVKVFDVSSGRCVKTLKGHTNYVFCCCFNPSGTLIASGSFDETIRIW-CARNGNTIFSIPGHEDPVSSVCFNRDGAYLASGSYDGIVRIWDSTTGTCVKTLIDEEHP----PITHVKFSPNGKYILASNLNN----TLKLWDYQKLRVLKEYTGHENSKYCVAANFSVTGGK-------WIVSGSEDHKVYIWNLQTREIL 355          

Query:   91 ICSIDIH---PSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKI----LYTDYTHLKCVNCVRWSPNGKY--LASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSA-----FQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIW-----------------------RTSDWKQETKLCDEIDKNSSCSFQR-LTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRS---------KETKEEFL-----LLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELGIPLT 1107
            + S+D+H    +GK    +    K   + +W  +     + +T EN P++    L     H   +N V++SP+ ++  LASG  +  + IW   KL+D + +     E   +      +++  H+ D+  L W P GT L S S D+ + +   D    K   +  +     GVCWDP G+Y+A+ S D  + +                           D   ETK+      +   SFQR L +SP+G   +A   ++    +  LY    + +    V    +       PT L             TKE  L     LL +     ++  + +    P+ V+ ++   ++ D S+  +   L+  SL+G  ++V+    + G  +T
Sbjct:   16 LLSVDLHHETRNGKYRLATASVQKEVRVRVWEFEFEMGLDPKTQENKPQLTVGFLANLVFHNHAINQVKFSPSKEHELLASGDCEGRITIW---KLSD-QPVPPPQDEMPSNKENWIRYKVLNHNSDVNALCWDPSGTQLASVSNDHTLAVH--DALTGKRLFVASNFRSPNGVCWDPSGKYIATMSPDRKMDLIDAVRGARLKHFSSALLPSMTIPSANGDLHLETKIHKLFHDDQLFSFQRALGFSPNG-EFIAAPCAHLELGSSDLYGTYFFRREDLGVKEAPYTFYPAPRPTFLVKFSPVTFSLLPSTKENHLGLPYRLLWIALNKDAIYFYDSQHSYPVAVVDNIHLNALTDASFSHDGRVLVVSSLEGFCSFVKINLTQWGEVMT 399          

Query:  211 DENCPKILYTDYTHLKCVNCVRWSPNGKY-LASGSVDAVVVIWVQKKLNDLEHIDKKFHES-------YRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNV---------DKFPE------KTAILNGHNSFIKGVCWDPVGRYLASQSEDHTL---------RIWRTSDWKQETKLC 669
            D   P I + D   L  V+    + NGKY LA+ SV   V + V +   ++  +D K  E+       + +      H+ + V  + S     L SG  + RI IW +         D+ P       +  +LN HNS +  +CWDP G  LAS S DHTL         R++  S+++    +C
Sbjct:    2 DHFMPIIYWHDRKGLLSVDLHHETRNGKYRLATASVQKEVRVRVWEFEFEMG-LDPKTQENKPQLTVGFLANLVFHNHAINQVKFSPSKEHELLASGDCEGRITIWKLSDQPVPPPQDEMPSNKENWIRYKVLN-HNSDVNALCWDPSGTQLASVSNDHTLAVHDALTGKRLFVASNFRSPNGVC 184          

Query:   85 TEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSP-HGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIW 633
             E+  ID HP+ K    +G  D    + IW            D      L T   H   V  V ++ NG +L +G  D +V ++  + + ++         +YR+      H  +++ LAW P H     SG  D  I+ W VD   E   + + H+  I  + W P+G  LA+ S D+  + W
Sbjct:  271 AEVRCIDWHPT-KGLIATGSRDTQQPVKIW------------DPKSGSCLATLQEHKSSVMAVEFNKNGNWLLTGGRDHLVKMYDIRMMKEMR--------TYRA------HKKEVISLAWHPIHEGLFVSGGGDGSIVYWMVDGEKEIGLLEHAHDQAIWSMKWHPLGHILATGSNDNNTKFW 427          

Query:   25 MRIVKPIYINYQNPQKDQILTEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHID---KKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDK-NSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKETKE------EFLLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELGIPLTLDEMKQFFEKTYGSGFV--VDNSAISKSKNNAFIIPESSAVLKXXXXXXXXNHDRKSTSLHLLNEKKTGP-NEQIICHTKTGKRRITPKFLSSLDD 1386
            MR++KP ++++ + Q       I S+DIH    KFAT G G   G + IWN+ P+ + + E D + PK+L     HL CVNCVRWS NG+ LASGS D +++IW +   +         +K HES++  + LRGH  D++DLAWSP+  YL S S+DN +IIW+   FP   A L GH   +KGV WDP+GR+LASQS+D +++IW T +W     + +  ++   +    RL+WSPDG  +V+    N G PT Q+  R+ W    D VGH++ + C R+  ++L  +E         ++  LA+GS+DRSLSVW T  +RP+VVI +LF  SI+DL+W  ++  LMACS+DGSIA ++FT++ELG  ++ +E      K YG  +V  +  SA         ++P+     K                    NE    P ++Q    TK GKRRITP F+   +D
Sbjct:    1 MRLLKPAWVHHDDKQ-------IFSVDIHKDCTKFATGGQGSDCGRVVIWNLLPVLSDKAEFDADVPKMLCQMDQHLACVNCVRWSQNGQNLASGSDDKLIMIWRKSAGSSGVFGTGGMQKNHESWKCFYTLRGHDGDVLDLAWSPNDVYLASCSIDNTVIIWDAQAFPHSVATLKGHTGLVKGVSWDPLGRFLASQSDDRSIKIWNTMNWSLSHTITEPFEECGGTTHILRLSWSPDGQYLVSAHAMNGGGPTAQIIEREGWKCDKDFVGHRKAVTCVRFHNSILSRQENDGSPSKPLQYCCLAVGSRDRSLSVWMTALQRPMVVIHELFNASILDLTWGPQECLLMACSVDGSIACLKFTEEELGKAISEEEQNAIIRKMYGKNYVNGLGKSAPVLEHPQRLLLPQGDKPTKFPLSNN--------------NEANQRPISKQTETRTKDGKRRITPMFIPLHED 446          

Query:   91 ICSIDIHPSGKKFAT-------SGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYT-HLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKK------LNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIW---------RTSDWKQETKLCDEI---------DKNSSCSFQRLTWSPDGSNIVATG--TSNNGAP----TCQLYNRDNWSKGVDMVGH-KQHIICARYFPTLLRSKETKEE----------FLLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELG 1095
            + S+DI  +G    +       SGG D +  + IW ++       +  E     L  D + H + VN VRWSPNG+ LASG  ++VV IW QK       + D +   ++  E + +   LRGH  DI DL+W+P+  +L SGSVDN  ++W+V    +  AIL+ H  +++GV WDP  +Y+A+ S D  +RI+         R S      K   E+         D      F+RL ++PDG  ++     T  +G      T   ++R + SK   ++   K++ +  R  P L R +    E           ++ A+ +K+ ++  + T +  P  ++S++    + DL+W  +   L+  S DG  + + F   ELG
Sbjct:   16 VLSVDIQQNGLGLRSPTICRLASGGSDAH--VLIWYVN-----RSDDAEGVDVELAADLSRHQRAVNAVRWSPNGELLASGDDESVVFIWKQKADHEVVNIVDADGCSEQDKEVWLTLKVLRGHREDIYDLSWAPNSQFLVSGSVDNTAMLWDVHSG-KSLAILDDHKGYVQGVAWDPCNQYIATMSTDRQMRIFDANTKRVLHRVSKCVLPVKEDHEMHGKSMRLYQDGTLQTFFRRLCFTPDGKLLLTPSGITDYDGVVKPINTSYGFSRHDLSKPAFVLPFPKEYAVAVRCSPVLYRLRPYNAEKNPPIISLPYRMIYAVATKN-AVFFYDTQQPVPFAIVSNIHYSRLTDLAWSSDGTVLIVSSTDGYCSLITFEPTELG 390          

Query:   91 ICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNV---DKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRI 630
            I  +  HP G  FA S G DK   I IW++          +    K + +D  H + +  +RWSP G+YLAS S DA   IW             K    +     L GH  ++  ++WS  G  L + S D  + IW V   D+F E  A+LN H   +K V W P    LAS S D+T+++
Sbjct:   17 IWGVAWHPKGNVFA-SCGEDK--AIRIWSL--------TGNTWSTKTILSD-GHKRTIREIRWSPCGQYLASASFDATTAIW------------SKSSGEFECNATLEGHENEVKSVSWSRSGGLLATCSRDKSVWIWEVAGDDEF-ECAAVLNPHTQDVKRVVWHPTKDILASASYDNTIKM 174          

Query:  409 LRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNV--DKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPT 864
            L+GH   I  +AW P G    S   D  I IW++  + +  KT + +GH   I+ + W P G+YLAS S D T  IW  S  + E   C+   +      + ++WS  G  ++AT + +      ++   D +     +  H Q +    + PT
Sbjct:   10 LQGHKGRIWGVAWHPKGNVFASCGEDKAIRIWSLTGNTWSTKTILSDGHKRTIREIRWSPCGQYLASASFDATTAIWSKSSGEFE---CNATLEGHENEVKSVSWSRSG-GLLATCSRDKSVWIWEVAGDDEFECAAVLNPHTQDVKRVVWHPT 159          

Query:  271 VRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLR-GHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFP-EKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNN 762
            V W P G   AS   D  + IW                 ++ +   L  GH   I ++ WSP G YL S S D    IW+      E  A L GH + +K V W   G  LA+ S D ++ IW  +    +   C  +    +   +R+ W P   +I+A+ + +N
Sbjct:   20 VAWHPKGNVFASCGEDKAIRIWSLTG------------NTWSTKTILSDGHKRTIREIRWSPCGQYLASASFDATTAIWSKSSGEFECNATLEGHENEVKSVSWSRSGGLLATCSRDKSVWIWEVA--GDDEFECAAVLNPHTQDVKRVVWHPT-KDILASASYDN 170          

Query:   91 ICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKL-NDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQ---SEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKETKEEFLLLALGSKDRSLSVWTTLRRRPL 966
            I ++  H  G++ A    G + G ++IW+            EN  +I   +  H   V  + W   G  LASGS D  ++   Q+ + N   HI +           LRGH  ++  L WSP   YL SG  DNR+++W  D +PE     + H + +K + W P    L +    S D  LR W         KL   I  N+      L W+ D   +V   T  +  P    +   +  +   + GH Q ++     P      E+      +  G  D +L  WT   ++ +
Sbjct:  190 ITAVSWHGEGRQVAI---GTQSGYVTIWDA-----------ENQKQINRLE-EHSARVTALAWC--GNRLASGSRDRSIL---QRDIRNPPTHITRC----------LRGHKLEVCGLQWSPSNRYLASGGSDNRLLVW-TDDWPEPIYAFDEHKAVVKALGWSPHKSGLLASGGGSADRCLRFWNV----LTGKLVKCI--NTGAQISNLAWARDSRELVT--THGHAQPQVIAWRYPSLKQMARLSGHTQRVLHLSVSP----DNES------IVTGGADETLRFWTVFTKQKI 436          

Query:   67 QKDQIL----TEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSP-HGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIW 633
            Q++++L     ++  +  HP  K    SG  D    I IW            D      L T + H   V  ++W+ NG +L + S D ++      KL D+ ++ ++           RGH  +   ++W P H    CSG  D  I+ WNV    E   +   H+S +  + W P+G  L S S DHT++ W
Sbjct:  262 QEERVLRGHGADVKCVHWHPQ-KGMIVSGSKDNQQPIKIW------------DPKSGIALATLHAHKSTVMDLKWNDNGNWLVTASRDHLL------KLFDIRNLREEVQ-------VFRGHKKEASSVSWHPIHEGLFCSGGSDGSILFWNVGTDKEIGCVETAHDSIVWTLAWHPLGHILCSGSNDHTIKFW 429          

Query:  145 GDKYGIISIW--NMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNR--IIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICAR-YFPTLLRSKETKEEFLLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELGIPLTLDEMKQFF 1131
            GD  G +  W  NM+ ++             +Y    H + +  + +SP      SGS D  + IW   +  + E +             LRGH  D+  + W P    + SGS DN+  I IW+  K     A L+ H S +  + W+  G +L + S DH L+++   + ++E ++     K +S     ++W P    +  +G S+       L+    W+ G D     + I C      +++ +        +L  GS D ++  WT  R RP  ++ D +  + +  S       L  C  D +I      +D +    +L   K F 
Sbjct:  206 GDHGGYVKYWQSNMNNVK-------------MYQ--AHKEAIRGISFSPTDSKFVSGSDDGTLRIWDFMRCQE-ERV-------------LRGHGADVKCVHWHPQKGMIVSGSKDNQQPIKIWD-PKSGIALATLHAHKSTVMDLKWNDNGNWLVTASRDHLLKLFDIRNLREEVQVFRGHKKEASS----VSWHPIHEGLFCSGGSDGSI----LF----WNVGTD-----KEIGCVETAHDSIVWTLAWHPLGHILCSGSNDHTIKFWT--RNRPGDLMRDKYNLNTLPASLAA----LDECEYDDAIIPGMGPEDRVEFTESLTADKGFI 486          

Query:   25 MRIVKPIYINYQNPQKDQILTEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHI---DKKFH--ESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDK-NSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKETKEE-------FLLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELGIPLTLDEMKQFFEKTYGSGFVVDNSAISKSKNNAFIIPESSAVLK------------XXXXXXXXNHDRKSTSL----HLLNEKKTGPNEQIICHTKTGKRRITPKFLSSLDDEDIEPDPAPSKRIYSPETIPEILVPNKSKEDENVLISNAVKVSSKFKSVLEEKFVKPDSPNIVSSSEDRRDS----LNSLKIKTQRKDDKANDNKSSCGIDSKSPKKDEKS--VDSISTKIG---------SSVEKSPKKDDK 1770
            M+++KP ++N+           I S+DIHP G KFAT G G+  G + IWNM P+  +E E +EN PK+L     HL CVNCVRWS NG YLASG  D +V++W +        +     K    E +R    LR H+ D++D+AWSPH  +L S SVDN I+IWN  KFPE    L GH   +KG+ WDPVG+Y+ASQ++DH+L++WRT DW+ ET +     +   +    RL+WSPDG  +V+    NN  PT Q+  RD W   +D VGH++ +   ++ P + + K+           +   A+GSKDRSLSVW T  +RPLVVI DLF  SI+D++W +    L+ CS+DG++A++ F+ DELG PL  +E     +  YG        AI+     +  I E+  +LK            + Q     N   K T++     L + +K    +Q+   T  G+RRITP  ++ LD  D  P    S  I    +    L P  S  D N   S  ++ S    +          SPN   ++E+ +DS    +NS+ +K+      A+  +    +DS+  ++ + +  V S+   IG         SS  K PK  D+
Sbjct:    1 MKLLKPSWVNHNG-------KPIFSVDIHPDGTKFATGGQGEDSGKVVIWNMAPVLREEDEKNENIPKLLCQMDNHLACVNCVRWSNNGLYLASGGDDKLVMVWKRAAFIGPSTVFGSSSKLANVEQWRCVTILRNHTGDVMDVAWSPHDVWLASCSVDNTIVIWNARKFPEIVMTLKGHTGLVKGLTWDPVGKYIASQADDHSLKVWRTMDWQLETNITKPFSECGGTTHVLRLSWSPDGQYLVSAHAMNNSGPTAQIIERDGWKTNMDFVGHRKAVTVVKFNPKIFKKKQKNGSTPKPSCPYCCCAVGSKDRSLSVWLTSLKRPLVVIHDLFDKSIMDITWTLNGLGLLVCSMDGTVAFLDFSQDELGDPLNEEEKNAIHQNIYGKSL-----AITMESQLSTTIIENPEMLKYQQERQGNQNANVAQGSGPENQTPKLTNVLNGESLEDIRKNLLKKQVETRTADGRRRITPLCIAQLDTGDFSPALFNSVPILPGSSASTQLTPQIS-SDSNTANSLGLRPSHDPSTT---------SPN--KTAEENKDSATAPVNSIGMKSTLLLTSASKIEPMKALDSRFTERSKATPGVTSVPITIGITPLDRAKDSSSVKEPKGKDE 602          

Query: 2209 WEITQTKQISVMAHFKDKLFVGDVCGFLHSFYLKGGRIQAPFSLDSGLTSLVCDGRYLIAVTVRATLYIWSIAPFAIFLKESFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSNK----SEFWSVSKLSSKNLINK--PLASMQSSESICDGPMKNLSSI---VKQELILDRLEIQVKLAESLHSCEEYKYWLLLWVRHLIEADKEVRVRDICQRFLGPIHTSTKSNWDPFILRYSKRELLKEILPLFALNLRLQRLYT 3018
            W+     +I +     D + V      L  F   G R+     L + +++L C G +++A+   ATL +W +      +K   ++ +    D T  +++ I+ +G   ++  +G ++ FN  +  W  + +  +     ++F +   LSS++++    PLA  Q            LSS    ++Q + L  LE Q+  A  L S  EY++WLL++ R L+    E R+R++CQ  LGP+H S+ S+W+  +L   KR+LL E+LP+   NLR QRL+T
Sbjct:  723 WDTLLPSRIIIATGSSDVVAVACEDRTLSVFTACGRRLIPSIMLPAPMSALHCSGHFVMALMASATLSVWDVQKQTALVKNESLNPILSGTDATVSQSL-ITQQGVAVVSLSNGKTYCFNSSLETWNLIADKQDSLVQCADFRNC--LSSQDVLGSMGPLALTQGRNLSAGRLASRLSSTPHHLQQGMTLAFLENQLSSALMLLSASEYRHWLLIYARFLVNEGYEHRLRELCQDLLGPVHKSSSSSWESTVLGLRKRDLLTEVLPVIGQNLRFQRLFT 998          

Query:  250 HLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLND----------LEHIDKKFH-ESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQE---TKLCDEI-------------DKNSSCSFQRLTWSPDGSNIVATG----TSNNGAPTCQLYNRDNWSKGV-DMVGHKQHIICARYFPTL--LRSKETKEEF-------------LLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELGIPL 1104
            H K VN VR+SP  + LASG  DA +++W   KLND           E  D + + ES+     LRGH  D+ D++W+  G ++ SGSVDN  I+W+V+K  +K  I N H S+++GV WDP+G+Y+++ S D  +R++   + K+    +K+                 D +    F+RLT++PDGS ++A         N   T  +++R ++ + +  +    +  +  R  P    LR+K  +++              L+ A+ S+D S+  + T +  P   +S++  +++ DLSW  +   L   S DG  +++ F + ELG PL
Sbjct:   65 HTKAVNVVRFSPTAEVLASGGDDAAILLW---KLNDNKEPEQTPTFQEEEDAQLNKESWSVVKTLRGHIEDVYDISWTSDGNFMASGSVDNTAIMWDVNKG-QKMCIFNDHKSYVQGVAWDPLGQYISTLSCDRVMRVYSAHNRKKAYSISKMTSSATADGEVKNYRMFHDDSMRSFFRRLTFTPDGSFLLAPAGCVEAGENVTNTTYVFSRKSFKRPIAHLPCPSKATLAVRCSPVYFELRTKRAEDDSLKPVANTFNLPYRLVFAVASED-SIFFYDTQQTLPFGYVSNIHYHTLSDLSWSRDGSFLAVSSTDGYCSFISFDEGELGTPL 391          

Query:  109 HPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKT--AILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTS--DWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVA 744
            +P+G   AT GG D+   I IW         KE D    K + +D  H + V  V WSP GKYLAS S DA   IW            KK  E +     L GH  ++  +AW+P G+ L + S D  + IW VD+  E    +++N H   +K V W P    LAS S D+ + I++    DW+    L     +    +   LT+ P+G  + +
Sbjct:   25 NPAGTTLATCGG-DR--AIRIWG--------KEGDSWECKCVLSD-GHQRTVRKVAWSPCGKYLASASFDATTCIW------------KKTDEDFECLTVLEGHENEVKCVAWAPSGSLLATCSRDKSVWIWEVDEEDEYECLSVVNSHTQDVKHVVWHPTQELLASASYDNKICIYKEEDDDWECRATL-----EGHESTVWSLTFDPEGRRLAS 211          

Query:  271 VRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLR-GHSYDIVDLAWSPHGTYLCSGSVDNRIIIW-NVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNR--DNWSKGVDMVGHKQHIICARYFPTLLRSKETKEEFLLLALGSKDRSLSVW---------TTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIA 1065
            V W+P G  LA+   D  + IW             K  +S+     L  GH   +  +AWSP G YL S S D    IW   D+  E   +L GH + +K V W P G  LA+ S D ++ IW   +  ++   C  +  + +   + + W P    ++A+ + +N    C +Y    D+W     + GH+  +    + P   R          LA  S DR++ +W         +    + +  +S     +I D++W         C L G++A
Sbjct:   22 VAWNPAGTTLATCGGDRAIRIW------------GKEGDSWECKCVLSDGHQRTVRKVAWSPCGKYLASASFDATTCIWKKTDEDFECLTVLEGHENEVKCVAWAPSGSLLATCSRDKSVWIWEVDE--EDEYECLSVVNSHTQDVKHVVWHPT-QELLASASYDN--KIC-IYKEEDDDWECRATLEGHESTVWSLTFDPEGRR----------LASCSDDRTVKIWKESTTGDGSSDESWKCICTLSGFHGRTIYDIAW---------CRLTGALA 262          

Query:  250 HLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVG-----RYLASQSEDHTLRIWRT 639
            H + V  V +SP GKYLASGS D  V  W      DL   +   H S       RGH++ ++ +AWSP G  L SG  +++I +W+     +    L GH  +I  +CW+P+      RYLAS S+D T+RIW T
Sbjct:  104 HTEAVISVAFSPTGKYLASGSGDTTVRFW------DLS-TETPHHTS-------RGHTHWVLSIAWSPDGKKLASGCKNSQIFLWDPVTGKQIGKTLTGHTKWITWLCWEPLHLNPECRYLASTSKDCTIRIWDT 224          

Query:  250 HLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWR 636
            H   VN V +SP+ + +AS S D  + IW  K    L                LRGH   +  +AWS     L SGS D+ + +W++ K  +  A L GH   +  V W P G+ +AS  +D  LRIWR
Sbjct:  362 HQALVNEVLFSPDTRLIASASFDKSIKIWDGKTGKYLN--------------SLRGHVGPVYQVAWSADSRLLVSGSSDSTLKVWDI-KTGKLNADLPGHADEVFAVDWSPDGQRVASGGKDKCLRIWR 475          

Query:   91 ICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIW--VQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAW-----SPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSD 645
            + S+   P+GK  A SG GD    +  W++        ET        +T   H   V  + WSP+GK LASG  ++ + +W  V  K      I K           L GH+  I  L W     +P   YL S S D  I IW+         IL GH   +  V W   G  L + S+D T+++WR  D
Sbjct:  108 VISVAFSPTGKYLA-SGSGDT--TVRFWDL------STETPH------HTSRGHTHWVLSIAWSPDGKKLASGCKNSQIFLWDPVTGK-----QIGKT----------LTGHTKWITWLCWEPLHLNPECRYLASTSKDCTIRIWDT-VLGHYDKILTGHTHSVTCVKWGGDG-LLYTSSQDRTIKVWRAKD 267          

Query:  394 RSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVD-KFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETK-LCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVD--MVGHKQHIICARYFPTLLRSKETKEEFLLLALGSKDRSLSVW 942
            R    L GH+  ++ +A+SP G YL SGS D  +  W++  + P  T+   GH  ++  + W P G+ LAS  ++  + +W     KQ  K L       +   ++ L  +P+   + +T      +  C +   D      D  + GH   + C ++               LL   S+DR++ VW
Sbjct:   96 RCTSSLEGHTEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHHTS--RGHTHWVLSIAWSPDGKKLASGCKNSQIFLWDPVTGKQIGKTLTGHTKWITWLCWEPLHLNPECRYLAST------SKDCTIRIWDTVLGHYDKILTGHTHSVTCVKWGGD-----------GLLYTSSQDRTIKVW 263          

Query:  226 KILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFH----ESYRSAFQLRGHSYDIVDLAWSPH---GTY---------------------LCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKETKEEFLLLALGSKDRSLSVW 942
            KIL T +TH   V CV+W  +G  L + S D  + +W  K       +    H     +  + + LR  +++  +   +P    G+                      L SGS D  + +WN  +  +  A L GH + +  V + P  R +AS S D +++IW      +  K  + +  +    +Q + WS D S ++ +G+S++   T ++++        D+ GH   +    + P   R          +A G KD+ L +W
Sbjct:  231 KIL-TGHTH--SVTCVKWGGDG-LLYTSSQDRTIKVWRAKDGVQCRTLQGHAHWVNTLALSTDYVLRTGAFEPANATINPQDLTGSLEEIKEKALKRYNSVRGEGHERLVSGSDDFTMFLWNPAEDKKPVARLTGHQALVNEVLFSPDTRLIASASFDKSIKIWD----GKTGKYLNSLRGHVGPVYQ-VAWSAD-SRLLVSGSSDS---TLKVWDIKTGKLNADLPGHADEVFAVDWSPDGQR----------VASGGKDKCLRIW 474          

Query:  250 HLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVG-----RYLASQSEDHTLRIWRT 639
            H + V  V +SP GKYLASGS D  V  W      DL   +   H S       RGH++ ++ +AWSP G  L SG  +++I +W+     +    L GH  +I  +CW+P+      RYLAS S+D T+RIW T
Sbjct:  104 HTEAVISVAFSPTGKYLASGSGDTTVRFW------DLS-TETPHHTS-------RGHTHWVLSIAWSPDGKKLASGCKNSQIFLWDPVTGKQIGKTLTGHTKWITWLCWEPLHLNPECRYLASTSKDCTIRIWDT 224          

Query:  250 HLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWR 636
            H   VN V +SP+ + +AS S D  + IW  K    L                LRGH   +  +AWS     L SGS D+ + +W++ K  +  A L GH   +  V W P G+ +AS  +D  LRIWR
Sbjct:  362 HQALVNEVLFSPDTRLIASASFDKSIKIWDGKTGKYLN--------------SLRGHVGPVYQVAWSADSRLLVSGSSDSTLKVWDI-KTGKLNADLPGHADEVFAVDWSPDGQRVASGGKDKCLRIWR 475          

Query:   91 ICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIW--VQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAW-----SPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSD 645
            + S+   P+GK  A SG GD    +  W++        ET        +T   H   V  + WSP+GK LASG  ++ + +W  V  K      I K           L GH+  I  L W     +P   YL S S D  I IW+         IL GH   +  V W   G  L + S+D T+++WR  D
Sbjct:  108 VISVAFSPTGKYLA-SGSGDT--TVRFWDL------STETPH------HTSRGHTHWVLSIAWSPDGKKLASGCKNSQIFLWDPVTGK-----QIGKT----------LTGHTKWITWLCWEPLHLNPECRYLASTSKDCTIRIWDT-VLGHYDKILTGHTHSVTCVKWGGDG-LLYTSSQDRTIKVWRAKD 267          

Query:  394 RSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVD-KFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETK-LCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVD--MVGHKQHIICARYFPTLLRSKETKEEFLLLALGSKDRSLSVW 942
            R    L GH+  ++ +A+SP G YL SGS D  +  W++  + P  T+   GH  ++  + W P G+ LAS  ++  + +W     KQ  K L       +   ++ L  +P+   + +T      +  C +   D      D  + GH   + C ++               LL   S+DR++ VW
Sbjct:   96 RCTSSLEGHTEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHHTS--RGHTHWVLSIAWSPDGKKLASGCKNSQIFLWDPVTGKQIGKTLTGHTKWITWLCWEPLHLNPECRYLAST------SKDCTIRIWDTVLGHYDKILTGHTHSVTCVKWGGD-----------GLLYTSSQDRTIKVW 263          

Query:  226 KILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFH----ESYRSAFQLRGHSYDIVDLAWSPH---GTY---------------------LCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKETKEEFLLLALGSKDRSLSVW 942
            KIL T +TH   V CV+W  +G  L + S D  + +W  K       +    H     +  + + LR  +++  +   +P    G+                      L SGS D  + +WN  +  +  A L GH + +  V + P  R +AS S D +++IW      +  K  + +  +    +Q + WS D S ++ +G+S++   T ++++        D+ GH   +    + P   R          +A G KD+ L +W
Sbjct:  231 KIL-TGHTH--SVTCVKWGGDG-LLYTSSQDRTIKVWRAKDGVQCRTLQGHAHWVNTLALSTDYVLRTGAFEPANATINPQDLTGSLEEIKEKALKRYNSVRGEGHERLVSGSDDFTMFLWNPAEDKKPVARLTGHQALVNEVLFSPDTRLIASASFDKSIKIWD----GKTGKYLNSLRGHVGPVYQ-VAWSAD-SRLLVSGSSDS---TLKVWDIKTGKLNADLPGHADEVFAVDWSPDGQR----------VASGGKDKCLRIW 474          

Query:   25 MRIVKPIYINYQNPQKDQILTEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHI---DKKFH--ESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDK-NSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKE-------TKEEFLLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELGIPLTLDEMKQFFEKTYG-----------SGFVVDNSAISKSKNNAFIIPESSAVLKXXXXXXXXNHDRKSTSLHLLNEKKTGPNEQIICHTKTGKRRITPKFLSSLDDEDIEPDPAPSKRIYSPETIPEILVPNKSKEDENVLISNAVKVSSKFKSVLE--------EKFVKPDSPNIVSSS 1584
            M+++KP ++N+           I S+DIHP G KFAT G G   G + IWNM P+  +E E +EN PK+L     HL CVNCVRWS +G YLASG  D ++++W +        +     K    E +R    LR HS D++D++WSPH  +L S SVDN ++IWN  KFPE  + L GH+  +KG+ WDPVG+Y+ASQ++D ++++WRT DW+ ET +    D+   +    RL+WSPDG  +V+    NN  PT Q+  RD W   +D VGH++ +   ++ P + + K+       T   +   A+GSKDRSLSVW T  +RPLVVI +LF  SI+D+SW +    ++ CS+DGS+AY+ F+ DELG PL+ +E     + TYG           S  V++N  + K +       +    ++ Q++    N         L + +K    +Q+   T  G+RRITP  ++ LD  D     A    I     +P  ++ ++S +    L SN    S   KS  E        E+ V  +S N  SSS
Sbjct:    1 MKLLKPTWVNHNG-------KPIFSVDIHPDGTKFATGGQGQDSGKVVIWNMPPLLKEEDEKNENIPKMLCQMDNHLACVNCVRWSNSGAYLASGGDDKLIMVWKRSGYIGPSTVFGSSSKLANVEQWRCLSILRSHSGDVMDVSWSPHDAWLASCSVDNTVVIWNALKFPEIISTLRGHSGLVKGLTWDPVGKYIASQADDRSIKVWRTMDWQLETSITKPFDECGGTTHVLRLSWSPDGHYLVSAHAMNNSGPTAQIIERDGWKANMDFVGHRKAVTVVKFNPKIFKKKQKNGSSTKTNCPYCCCAVGSKDRSLSVWLTCLKRPLVVIHELFDKSIMDISWTLNGLGILVCSMDGSVAYLDFSQDELGDPLSEEEKNNIHQTTYGKSLAITTEPQLSNTVIENPEMLKFQQRQQPHQDGEHRVQAQREAPAHNVASMVNGESLEDIRKNLLKKQVETRTADGRRRITPLCIAQLDTGDF--STAFFNSIPISGALPGSMLTSQSNQQLISLDSNTTSSSGAPKSNAELAGNTKPAEETVNKESGNASSSS 543          

Query: 2191 NNDQKLWEITQTKQISVMAHFKDKLFVGDVCGFLHSFYLKGGRIQAPFSLDSGLTSLVCDGRYLIAVTVRATLYIWSIAPFAIFLKESFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSNK----SEFWSVSKLSSKNLINKPLASMQSSESICDGPMKNLSSI---VKQELILDRLEIQVKLAESLHSCEEYKYWLLLWVRHLIEADKEVRVRDICQRFLGPIHTSTKSNWDPFILRYSKRELLKEILPLFALNLRLQRLYT 3018
            + + K WE   T +I   A   + + V      L  F   G R+  P  L S +++L C G Y++A+T  A L +W +    + +K+  +  L    D T +    ++  G   L   +G ++ F+  ++ W  V +  +     +++ +        + + PLA +Q   S        L ++   V+QE  +  LE QV  A  L S +EY++WLL++ R+L+    E R+R++CQ  LGP+H S+ S W+  IL   KRELLKE+LPL   NLR QRL+T
Sbjct:  718 HREGKEWEAVLTSRILAAAGSNEVVCVACEKRMLSIFSGSGRRLFPPIILPSPISTLQCTGSYVMALTAAAALSVWDVQNQKVIIKDESLQPLLSGNDMT-VSQTLLTKRGIPVLNLSNGKAYCFSPSLSTWSLVSDKQDSLTQCADYRNCMPSQDAIMCSGPLAIIQGRASNAGRQAARLFTMPHQVQQETTMAYLENQVAAALMLQSSQEYRHWLLIYARYLVNEGFEQRLREVCQDLLGPVHNSSDSQWESRILGLRKRELLKELLPLIGQNLRFQRLFT 999          

Query:   91 ICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHI---DKKFH--ESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDK-NSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKE-------TKEEFLLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELGIPLTLDEMKQFFEKTYG-----------SGFVVDNSAISKSKNNAFIIPESSAVLKXXXXXXXXNHDRKSTSLHLLNEKKTGPNEQIICHTKTGKRRITPKFLSSLD---DEDIEPDPAPSKRIYSPETIPEILVPNKSKEDENVLISNAVKVSSKFKSV--LEEKFVKPDSP--NIVSSSEDRRDSLNSLKIKTQRKDDKAND--NKSSCGIDSKSPKKDEKSVDSISTKIGSSVEK 1749
            I S+DIHP G KFAT G G   G + IWNM P+  +E E +EN PK+L     HL CVNCVRWS +G YLASG  D ++++W +        +     K    E +R    LR HS D++D++WSPH  +L S SVDN ++IWN  KFPE  + L GH+  +KG+ WDPVG+Y+ASQ++D ++++WRT DW+ ET +    D+   +    RL+WSPDG  +V+    NN  PT Q+  RD W   +D VGH++ +   ++ P + + K+       T   +   A+GSKDRSLSVW T  +RPLVVI +LF  SI+D+SW +    ++ CS+DGS+AY+ F+ DELG PL+ +E     + TYG           S  V++N  + K +       +    ++ Q++    N         L + +K    +Q+   T  G+RRITP  ++ LD   +       AP+     P+  P   + ++  E        A        +V  L+E+ V  DS    ++ SS D  + + + K  ++RK +   D   K   G     P+KD +   S++ ++ S+ EK
Sbjct:   22 IFSVDIHPDGTKFATGGQGQDSGKVVIWNMPPLLKEEDEKNENIPKMLCQMDNHLACVNCVRWSNSGAYLASGGDDKLIMVWKRSGYIGPSTVFGSSSKLANVEQWRCLSILRSHSGDVMDVSWSPHDAWLASCSVDNTVVIWNALKFPEIISTLRGHSGLVKGLTWDPVGKYIASQADDRSIKVWRTMDWQLETSITKPFDECGGTTHVLRLSWSPDGHYLVSAHAMNNSGPTAQIIERDGWKANMDFVGHRKAVTVVKFNPKIFKKKQKNGSSTKTNCPYCCCAVGSKDRSLSVWLTCLKRPLVVIHELFDKSIMDISWTLNGLGILVCSMDGSVAYLDFSQDELGDPLSEEEKNNIHQTTYGKSLAITTEPQLSNTVIENPEMLKFQQRQQPHQDGEHRVQAQREAPAHNVASMVNGESLEDIRKNLLKKQVETRTADGRRRITPLCIAQLDTGGNASSSSPVAPNSISAQPKIEPMKALDSRFTERSKATSGTAGVAHLNQTAVDRLKEQNVTKDSKPREVLESSSDSEEKIPATKQLSKRKGESDADLGEKRKKG----RPRKDPRLSVSLTLQVASTSEK 603          

Query: 2191 NNDQKLWEITQTKQISVMAHFKDKLFVGDVCGFLHSFYLKGGRIQAPFSLDSGLTSLVCDGRYLIAVTVRATLYIWSIAPFAIFLKESFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSNK----SEFWSVSKLSSKNLINKPLASMQSSESICDGPMKNLSSI---VKQELILDRLEIQVKLAESLHSCEEYKYWLLLWVRHLIEADKEVRVRDICQRFLGPIHTSTKSNWDPFILRYSKRELLKEILPLFALNLRLQRLYT 3018
            + + K WE   T +I   A   + + V      L  F   G R+  P  L S +++L C G Y++A+T  A L +W +    + +K+  +  L    D T +    ++  G   L   +G ++ F+  ++ W  V +  +     +++ +        + + PLA +Q   S        L ++   V+QE  +  LE QV  A  L S +EY++WLL++ R+L+    E R+R++CQ  LGP+H S+ S W+  IL   KRELLKE+LPL   NLR QRL+T
Sbjct:  658 HREGKEWEAVLTSRILAAAGSNEVVCVACEKRMLSIFSGSGRRLFPPIILPSPISTLQCTGSYVMALTAAAALSVWDVQNQKVIIKDESLQPLLSGNDMT-VSQTLLTKRGIPVLNLSNGKAYCFSPSLSTWSLVSDKQDSLTQCADYRNCMPSQDAIMCSGPLAIIQGRASNAGRQAARLFTMPHQVQQETTMAYLENQVAAALMLQSSQEYRHWLLIYARYLVNEGFEQRLREVCQDLLGPVHNSSDSQWESRILGLRKRELLKELLPLIGQNLRFQRLFT 939          

Query:   31 IVKPIYINYQNPQKDQILTEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHI---DKKFH--ESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDK-NSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKE-------TKEEFLLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELGIPLTLDEMKQFFEKTYG-----------SGFVVDNSAISKSKNNAFIIPESSAVLKXXXXXXXXNHDRKSTSLHLLNEKKTGPNEQIICHTKTGKRRITPKFLSSLDDEDIEPDPAPSKRIYSPETIPEILVPNKSKEDENVLISNAVKVSSKFKSVLE--------EKFVKPDSPNIVSSS 1584
            ++KP ++N+           I S+DIHP G KFAT G G   G + IWNM P+  +E E +EN PK+L     HL CVNCVRWS +G YLASG  D ++++W +        +     K    E +R    LR HS D++D++WSPH  +L S SVDN ++IWN  KFPE  + L GH+  +KG+ WDPVG+Y+ASQ++D ++++WRT DW+ ET +    D+   +    RL+WSPDG  +V+    NN  PT Q+  RD W   +D VGH++ +   ++ P + + K+       T   +   A+GSKDRSLSVW T  +RPLVVI +LF  SI+D+SW +    ++ CS+DGS+AY+ F+ DELG PL+ +E     + TYG           S  V++N  + K +       +    ++ Q++    N         L + +K    +Q+   T  G+RRITP  ++ LD  D     A    I     +P  ++ ++S +    L SN    S   KS  E        E+ V  +S N  SSS
Sbjct:   50 LLKPTWVNHNG-------KPIFSVDIHPDGTKFATGGQGQDSGKVVIWNMPPLLKEEDEKNENIPKMLCQMDNHLACVNCVRWSNSGAYLASGGDDKLIMVWKRSGYIGPSTVFGSSSKLANVEQWRCLSILRSHSGDVMDVSWSPHDAWLASCSVDNTVVIWNALKFPEIISTLRGHSGLVKGLTWDPVGKYIASQADDRSIKVWRTMDWQLETSITKPFDECGGTTHVLRLSWSPDGHYLVSAHAMNNSGPTAQIIERDGWKANMDFVGHRKAVTVVKFNPKIFKKKQKNGSSTKTNCPYCCCAVGSKDRSLSVWLTCLKRPLVVIHELFDKSIMDISWTLNGLGILVCSMDGSVAYLDFSQDELGDPLSEEEKNNIHQTTYGKSLAITTEPQLSNTVIENPEMLKFQQRQQPHQDGEHRVQAQREAPAHNVASMVNGESLEDIRKNLLKKQVETRTADGRRRITPLCIAQLDTGDF--STAFFNSIPISGALPGSMLTSQSNQQLISLDSNTTSSSGAPKSNAELAGNTKPAEETVNKESGNASSSS 590          

Query: 2191 NNDQKLWEITQTKQISVMAHFKDKLFVGDVCGFLHSFYLKGGRIQAPFSLDSGLTSLVCDGRYLIAVTVRATLYIWSIAPFAIFLKESFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSNK----SEFWSVSKLSSKNLINKPLASMQSSESICDGPMKNLSSI---VKQELILDRLEIQVKLAESLHSCEEYKYWLLLWVRHLIEADKEVRVRDICQRFLGPIHTSTKSNWDPFILRYSKRELLKEILPLFALNLRLQRLYT 3018
            + + K WE   T +I   A  K  + V      L  F   G R+  P  L S +++L C G Y++A+T  A L +W +    + +K+  +  L    D T +    ++  G   L   +G ++ F+  ++ W  V +  +     +++ +        + + PLA +Q   S        L ++   V+QE  +  LE QV  A  L S +EY++WLL++ R+L+    E R+R++CQ  LGP+H S+ S W+  IL   KRELLKE+LPL   NLR QRL+T
Sbjct:  765 HREGKEWEAVLTSRILAAAGSKSVVCVACEKRMLSIFSGSGRRLFPPIILPSPISTLQCTGSYVMALTAAAALSVWDVQNQKVIIKDESLQPLLSGNDMT-VSQTLLTKRGIPVLNLSNGKAYCFSPSLSTWSLVSDKQDSLTQCADYRNCMPSQDAIMCSGPLAIIQGRASNAGRQAARLFTMPHQVQQETTMAYLENQVAAALMLQSSQEYRHWLLIYARYLVNEGFEQRLREVCQDLLGPVHNSSDSQWESRILGLRKRELLKELLPLIGQNLRFQRLFT 1046          

Query:   91 ICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHI---DKKFH--ESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDK-NSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKE-------TKEEFLLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELGIPLTLDEMKQFFEKTYG-----------SGFVVDNSAISKSKNNAFIIPESSAVLKXXXXXXXXNHDRKSTSLHLLNEKKTGPNEQIICHTKTGKRRITPKFLSSLDDEDIEPDPAPSKRIYSPETIPEILVPNKSKEDENVLISNAVKVSSKFKSVLE--------EKFVKPDSPNIVSSSEDRRDSLNS------LKIKTQRKDDKANDNKSSCGIDSKS 1686
            I S+DIHP G KFAT G G   G + IWNM P+  +E E +EN PK+L     HL CVNCVRWS +G YLASG  D ++++W +        +     K    E +R    LR HS D++D++WSPH  +L S SVDN ++IWN  KFPE  + L GH+  +KG+ WDPVG+Y+ASQ++D ++++WRT DW+ ET +    D+   +    RL+WSPDG  +V+    NN  PT Q+  RD W   +D VGH++ +   ++ P + + K+       T   +   A+GSKDRSLSVW T  +RPLVVI +LF  SI+D+SW +    ++ CS+DGS+AY+ F+ DELG PL+ +E     + TYG           S  V++N  + K +       +    ++ Q++    N         L + +K    +Q+   T  G+RRITP  ++ LD  D     A    I     +P  ++ ++S +    L SN    S   KS  E        E+ V  +S N  SSS    +S+++      +K    R  +++     + GI  K+
Sbjct:   22 IFSVDIHPDGTKFATGGQGQDSGKVVIWNMPPLLKEEDEKNENIPKMLCQMDNHLACVNCVRWSNSGAYLASGGDDKLIMVWKRSGYIGPSTVFGSSSKLANVEQWRCLSILRSHSGDVMDVSWSPHDAWLASCSVDNTVVIWNALKFPEIISTLRGHSGLVKGLTWDPVGKYIASQADDRSIKVWRTMDWQLETSITKPFDECGGTTHVLRLSWSPDGHYLVSAHAMNNSGPTAQIIERDGWKANMDFVGHRKAVTVVKFNPKIFKKKQKNGSSTKTNCPYCCCAVGSKDRSLSVWLTCLKRPLVVIHELFDKSIMDISWTLNGLGILVCSMDGSVAYLDFSQDELGDPLSEEEKNNIHQTTYGKSLAITTEPQLSNTVIENPEMLKFQQRQQPHQDGEHRVQAQREAPAHNVASMVNGESLEDIRKNLLKKQVETRTADGRRRITPLCIAQLDTGDF--STAFFNSIPISGALPGSMLTSQSNQQLISLDSNTTSSSGAPKSNAELAGNTKPAEETVNKESGNASSSSPVAPNSISAQPKIEPMKALDSRFTERSKATSGTAGIKVKT 589          

Query: 2191 NNDQKLWEITQTKQISVMAHFKDKLFVGDVCGFLHSFYLKGGRIQAPFSLDSGLTSLVCDGRYLIAVTVRATLYIWSIAPFAIFLKESFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSNK----SEFWSVSKLSSKNLINKPLASMQSSESICDGPMKNLSSI---VKQELILDRLEIQVKLAESLHSCEEYKYWLLLWVRHLIEADKEVRVRDICQRFLGPIHTSTKSNWDPFILRYSKRELLKEILPLFALNLRLQRLYT 3018
            + + K WE   T +I   A   + + V      L  F   G R+  P  L S +++L C G Y++A+T  A L +W +    + +K+  +  L    D T +    ++  G   L   +G ++ F+  ++ W  V +  +     +++ +        + + PLA +Q   S        L ++   V+QE  +  LE QV  A  L S +EY++WLL++ R+L+    E R+R++CQ  LGP+H S+ S W+  IL   KRELLKE+LPL   NLR QRL+T
Sbjct:  725 HREGKEWEAVLTSRILAAAGSNEVVCVACEKRMLSIFSGSGRRLFPPIILPSPISTLQCTGSYVMALTAAAALSVWDVQNQKVIIKDESLQPLLSGNDMT-VSQTLLTKRGIPVLNLSNGKAYCFSPSLSTWSLVSDKQDSLTQCADYRNCMPSQDAIMCSGPLAIIQGRASNAGRQAARLFTMPHQVQQETTMAYLENQVAAALMLQSSQEYRHWLLIYARYLVNEGFEQRLREVCQDLLGPVHNSSDSQWESRILGLRKRELLKELLPLIGQNLRFQRLFT 1006          

Query:   91 ICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIW----------VQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDK-NSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKE-------TKEEFLLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELGIPLTLDEMKQFFEKTYG-----------SGFVVDNSAISKSKNNAFIIPESSAVLKXXXXXXXXNHDRKSTSLHLLNEKKTGPNEQIICHTKTGKRRITPKFLSSLDDEDIEPDPAPSKRIYSPETIPEILVPNKSKEDENVLISNAVKVSSKFKSVLE--------EKFVKPDSPNIVSSSEDRRDSLNS 1611
            I S+DIHP G KFAT G G   G + IWNM P+  +E E +EN PK+L     HL CVNCVRWS +G YLASG  D ++++W          V    + L ++     E +R    LR HS D++D++WSPH  +L S SVDN ++IWN  KFPE  + L GH+  +KG+ WDPVG+Y+ASQ++D ++++WRT DW+ ET +    D+   +    RL+WSPDG  +V+    NN  PT Q+  RD W   +D VGH++ +   ++ P + + K+       T   +   A+GSKDRSLSVW T  +RPLVVI +LF  SI+D+SW +    ++ CS+DGS+AY+ F+ DELG PL+ +E     + TYG           S  V++N  + K +       +    ++ Q++    N         L + +K    +Q+   T  G+RRITP  ++ LD  D     A    I     +P  ++ ++S +    L SN    S   KS  E        E+ V  +S N  SSS    +S+++
Sbjct:   22 IFSVDIHPDGTKFATGGQGQDSGKVVIWNMPPLLKEEDEKNENIPKMLCQMDNHLACVNCVRWSNSGAYLASGGDDKLIMVWKRSGYIGPSTVFGSSSKLANV-----EQWRCLSILRSHSGDVMDVSWSPHDAWLASCSVDNTVVIWNALKFPEIISTLRGHSGLVKGLTWDPVGKYIASQADDRSIKVWRTMDWQLETSITKPFDECGGTTHVLRLSWSPDGHYLVSAHAMNNSGPTAQIIERDGWKANMDFVGHRKAVTVVKFNPKIFKKKQKNGSSTKTNCPYCCCAVGSKDRSLSVWLTCLKRPLVVIHELFDKSIMDISWTLNGLGILVCSMDGSVAYLDFSQDELGDPLSEEEKNNIHQTTYGKSLAITTEPQLSNTVIENPEMLKFQQRQQPHQDGEHRVQAQREAPAHNVASMVNGESLEDIRKNLLKKQVETRTADGRRRITPLCIAQLDTGDF--STAFFNSIPISGALPGSMLTSQSNQQLISLDSNTTSSSGAPKSNAELAGNTKPAEETVNKESGNASSSSPVAPNSISA 558          

Query: 2191 NNDQKLWEITQTKQISVMAHFKDKLFVGDVCGFLHSFYLKGGRIQAPFSLDSGLTSLVCDGRYLIAVTVRATLYIWSIAPFAIFLKESFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSNK----SEFWSVSKLSSKNLINKPLASMQSSESICDGPMKNLSSI---VKQELILDRLEIQVKLAESLHSCEEYKYWLLLWVRHLIEADKEVRVRDICQRFLGPIHTSTKSNWDPFILRYSKRELLKEILPLFALNLRLQRLYT 3018
            + + K WE   T +I   A   + + V      L  F   G R+  P  L S +++L C G Y++A+T  A L +W +    + +K+  +  L    D T +    ++  G   L   +G ++ F+  ++ W  V +  +     +++ +        + + PLA +Q   S        L ++   V+QE  +  LE QV  A  L S +EY++WLL++ R+L+    E R+R++CQ  LGP+H S+ S W+  IL   KRELLKE+LPL   NLR QRL+T
Sbjct:  714 HREGKEWEAVLTSRILAAAGSNEVVCVACEKRMLSIFSGSGRRLFPPIILPSPISTLQCTGSYVMALTAAAALSVWDVQNQKVIIKDESLQPLLSGNDMT-VSQTLLTKRGIPVLNLSNGKAYCFSPSLSTWSLVSDKQDSLTQCADYRNCMPSQDAIMCSGPLAIIQGRASNAGRQAARLFTMPHQVQQETTMAYLENQVAAALMLQSSQEYRHWLLIYARYLVNEGFEQRLREVCQDLLGPVHNSSDSQWESRILGLRKRELLKELLPLIGQNLRFQRLFT 995          

Query:   25 MRIVKPIYINYQNPQKDQILTEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHI---DKKFH--ESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDK-NSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKE-----TKEE--FLLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELGIPLTLDEMKQFFEKTYGSGFVVDNSAISKSKNNAFIIPESSAVLKXXXXXXXXNHDRKSTSLH----------------LLNEKKTGPNEQIICHTKTGKRRITPKFLSSLDDEDI 1395
            M+++KP ++N+           I S+DIHP G KFAT G G   G + IWNM P+  ++ E DEN PK+L     HL CVNCVRWS +G YLASG  D ++++W +        +     K    E +R    LR HS D++D+AWSPH  +L S SVDN ++IWN  KFPE  A L GH+  +KG+ WDPVG+Y+ASQ++D +L++WRT DW+ ET +    D+   +    RL+WSPDG  +V+    NN  PT Q+  R+ W   +D VGH++ +   ++ P + + K+     TK    +   A+GSKDRSLSVW T  +RPLVVI +LF  SI+D+SW +    ++ CS+DGS+A++ F+ DELG PL+ +E  +  + TYG    +    +++++ +  +I E+  +LK Q++QQ    D+K+ +                  L + +K    +Q+   T  G+RRITP  ++ LD  D 
Sbjct:    1 MKLLKPTWVNHNG-------KPIFSVDIHPDGTKFATGGQGQDSGKVVIWNMSPVLQEDDEKDENIPKMLCQMDNHLACVNCVRWSNSGMYLASGGDDKLIMVWKRATYIGPSTVFGSSGKLANVEQWRCVSILRSHSGDVMDVAWSPHDAWLASCSVDNTVVIWNAVKFPEILATLRGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTLDWQLETSITKPFDECGGTTHVLRLSWSPDGHYLVSAHAMNNSGPTAQIIEREGWKTNMDFVGHRKAVTVVKFNPKIFKKKQKNGSSTKPSCPYCCCAVGSKDRSLSVWLTCLKRPLVVIHELFDKSIMDISWTLNGLGILVCSMDGSVAFLDFSQDELGDPLSEEEKSRIHQSTYGKSLAI----MTEAQLSTAVI-ENPEMLKYQRRQQQQQLDQKNATTRETSSASSVTGVVNGESLEDIRKNLLKKQVETRTADGRRRITPLCIAQLDTGDF 474          

Query: 2191 NNDQKLWEITQTKQISVMAHFKDKLFVGDVCGFLHSFYLKGGRIQAPFSLDSGLTSLVCDGRYLIAVTVRATLYIWSIAPFAIFLKESFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSNK----SEFWSVSKLSSKNLINKPLASMQSSESICDGPMKNLSSI---VKQELILDRLEIQVKLAESLHSCEEYKYWLLLWVRHLIEADKEVRVRDICQRFLGPIHTSTKSNWDPFILRYSKRELLKEILPLFALNLRLQRLYT 3018
            N + K WE   + ++   A   D + V      L  F   G R+  P  L S +++L C G Y++A+T  ATL +W +    + +KE  +H +    D T +  I ++  G   +    G ++ FN  ++ W  V +  +     ++F +        L + PLA +Q   S        L S+   V+QE  L  LE QV  A +L S  EY++WLLL+ R+L+    E R+R+IC+  LGP+H ST S W+  ++   KRELLKE+LP+   NLR QRL+T
Sbjct:  722 NREGKEWETVLSSRVLTAAGSCDVVCVACEKRMLSVFSTCGRRLLPPILLPSPISTLHCTGPYVMALTAAATLSVWDVHRQVVVVKEESLHSILSGSDMT-VSQILLTQHGIPVMNLSDGKAYCFNPSLSTWNLVSDKQDSLAQCADFRNSLPSQDAMLCSGPLAIIQGRTSNSGRQAARLFSVPHVVQQETTLAYLENQVAAALTLQSSHEYRHWLLLYARYLVNEGFEYRLREICKDLLGPVHCSTGSQWESTVVGLRKRELLKELLPVIGQNLRFQRLFT 1003          

Query:  178 MDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIW----------VQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDK-NSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKETKEE-------FLLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELGIPLTLDEMKQFFEKTYGSGFVVDNSAISKSKNNAFIIPESSAVLKXXXXXXXXNHDRKSTSLH----------------LLNEKKTGPNEQIICHTKTGKRRITPKFLSSLD 1383
            M P+  ++ E DEN PK+L     HL CVNCVRWS +G YLASG  D ++++W          V      L ++     E +R    LR HS D++D+AWSPH  +L S SVDN ++IWN  KFPE  A L GH+  +KG+ WDPVG+Y+ASQ++D +L++WRT DW+ ET +    D+   +    RL+WSPDG  +V+    NN  PT Q+  R+ W   +D VGH++ +   ++ P + + K+           +   A+GSKDRSLSVW T  +RPLVVI +LF  SI+D+SW +    ++ CS+DGS+A++ F+ DELG PL+ +E  +  + TYG        AI      +  + E+  +LK Q++QQ    D+K+ +                  L + +K    +Q+   T  G+RRITP  ++ LD
Sbjct:    1 MSPVLQEDDEKDENIPKMLCQMDNHLACVNCVRWSNSGMYLASGGDDKLIMVWKRATYIGPSTVFGSSGKLANV-----EQWRCVSILRSHSGDVMDVAWSPHDAWLASCSVDNTVVIWNAVKFPEILATLRGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTLDWQLETSITKPFDECGGTTHVLRLSWSPDGHYLVSAHAMNNSGPTAQIIEREGWKTNMDFVGHRKAVTVVKFNPKIFKKKQKNGSSTKPSCPYCCCAVGSKDRSLSVWLTCLKRPLVVIHELFDKSIMDISWTLNGLGILVCSMDGSVAFLDFSQDELGDPLSEEEKSRIHQSTYGKSL-----AIMTEAQLSTAVIENPEMLKYQRRQQQQQLDQKNATTRETSSASSVTGVVNGESLEDIRKNLLKKQVETRTADGRRRITPLCIAQLD 426          

Query:  250 HLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDK-KFH---------ESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEI----------------DKNSSCSFQRLTWSPDGSNIVATG----TSNNGAPTCQLYNRDNWSKGVDMV---GHKQHII--CARYF---PTLLRSKETKEEF---------LLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELGIPL 1104
            H K VN VR+SP G+ LASG  DAV+++W   K+ND +  ++  F          E++     LRGH  D+ D+ W+  G  + S SVDN +IIW+V K  +K +I N H S+++GV WDP+G+Y+A+ S D  LRI+ T   +    +   +                D +    F+RL+++PDGS ++       +  N   T  +++R +  + +  +   G     +  C  YF   P     K ++E           ++ A+ S+D S+ ++ T +  P   +S++  +++ D+SW  +   L   S DG   +V F   ELGIPL
Sbjct:   65 HTKAVNVVRFSPTGEILASGGDDAVILLW---KMNDSKEPEQIAFQDEEEAQLNKENWTVVKTLRGHLEDVYDICWATDGNLMTSASVDNTVIIWDVSKG-QKISIFNEHKSYVQGVTWDPLGQYIATLSCDRVLRIYNTQKKRVAFNISKMLSGQGPEGEARSFRMFHDDSMKSFFRRLSFTPDGSLLLTPAGCMESGENVTNTTYVFSRKHLKRPIAHLPCPGKATLAVRCCPVYFELRPVAETEKASEEPSPELVNLPYRMVFAVASED-SVLLYDTQQSFPFGYVSNIHYHTLSDISWSSDGAFLAISSTDGYCTFVTFEKGELGIPL 391          

Query:  250 HLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDK-KFH---------ESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEI----------------DKNSSCSFQRLTWSPDGSNIVATG----TSNNGAPTCQLYNRDNWSKGVDMV---GHKQHII--CARYF---PTLLRSKETKEEF---------LLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELGIPL 1104
            H K VN VR+SP G+ LASG  DAV+++W   K+ND +  ++  F          E++     LRGH  D+ D+ W+  G  + S SVDN +IIW+V K  +K +I N H S+++GV WDP+G+Y+A+ S D  LRI+ T   +    +   +                D +    F+RL+++PDGS ++       +  N   T  +++R +  + +  +   G     +  C  YF   P     K ++E           ++ A+ S+D S+ ++ T +  P   +S++  +++ D+SW  +   L   S DG   +V F   ELGIPL
Sbjct:   65 HTKAVNVVRFSPTGEILASGGDDAVILLW---KMNDSKEPEQIAFQDEEEAQLNKENWTVVKTLRGHLEDVYDICWATDGNLMTSASVDNTVIIWDVSKG-QKISIFNEHKSYVQGVTWDPLGQYIATLSCDRVLRIYNTQKKRVAFNISKMLSGQGPEGEARSFRMFHDDSMKSFFRRLSFTPDGSLLLTPAGCMESGENVTNTTYVFSRKHLKRPIAHLPCPGKATLAVRCCPVYFELRPVAETEKASEEPSPELVNLPYRMVFAVASED-SVLLYDTQQSFPFGYVSNIHYHTLSDISWSSDGAFLAISSTDGYCTFVTFEKGELGIPL 391          

Query:  250 HLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVG-----RYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDG 729
            H + V  V +SP GKYLASGS D  V  W      DL         +    F  +GH + ++ ++WSP G  L SG  + ++++W+     +    L GH+ +I G+ W+P+      RY+AS S+D ++R+W T+  +     C+ I    + S   L W  DG
Sbjct:  113 HSEAVISVAFSPTGKYLASGSGDTTVRFW------DLS--------TETPHFTCKGHRHWVLSISWSPDGKKLASGCKNGQVLLWDPSTGLQVGRTLTGHSKWITGLSWEPLHMNPECRYVASSSKDGSVRVWDTTAGR-----CERILTGHTQSVTCLRWGGDG 258          

Query:  250 HLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWR 636
            H   +N V +SP+ + +AS S D  + +W  +    L                LRGH   +  +AWS     L SGS D+ + +W+V K  +    L GH   +  V W P G+ +AS  +D  LRIWR
Sbjct:  371 HQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLA--------------SLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDV-KAQKLATDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIWR 484          

Query:   91 ICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAW-----SPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSD 645
            + S+   P+GK  A SG GD    +  W++        ET        +T   H   V  + WSP+GK LASG  +  V++W                   +    L GHS  I  L+W     +P   Y+ S S D  + +W+         IL GH   +  + W   G  L S S+D T+++WR  D
Sbjct:  117 VISVAFSPTGKYLA-SGSGDT--TVRFWDL------STETPH------FTCKGHRHWVLSISWSPDGKKLASGCKNGQVLLWDPST-------------GLQVGRTLTGHSKWITGLSWEPLHMNPECRYVASSSKDGSVRVWDTTA-GRCERILTGHTQSVTCLRWGGDG-LLYSASQDRTIKVWRAHD 276          

Query:  394 RSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVD-KFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETK-LCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKETKEEFLLLALGSKDRSLSVW 942
            R    L GHS  ++ +A+SP G YL SGS D  +  W++  + P  T    GH  ++  + W P G+ LAS  ++  + +W  S   Q  + L       +  S++ L  +P+   + +  +S +G  + ++++         + GH Q + C R+               LL   S+DR++ VW
Sbjct:  105 RCTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTC--KGHRHWVLSISWSPDGKKLASGCKNGQVLLWDPSTGLQVGRTLTGHSKWITGLSWEPLHMNPECRYVAS--SSKDG--SVRVWDTTAGRCERILTGHTQSVTCLRWGGD-----------GLLYSASQDRTIKVW 272          

Query:  100 IDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIW------VQKKLNDLEH--------IDKKFH-------ESYRSAFQLRGHSYDIVDLAWSPHGTY-------LCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKETKEEFLLLALGSKDRSLSVW 942
            + ++P  +  A+S    K G + +W+          T   C +IL     H + V C+RW  +G  L S S D  + +W      + + L    H         D           E+  +A  L+G   ++ + A S +          L SGS D  + +W+  +  +  A + GH + I  V + P  R +AS S D ++++W     K    L     +    +  ++ WS D S ++ +G+S++   T ++++        D+ GH   +    + P   R          +A G KD+ L +W
Sbjct:  210 LHMNPECRYVASS---SKDGSVRVWDT---------TAGRCERILTG---HTQSVTCLRWGGDG-LLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEATVNAQDLQGSLKELKERASSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLARMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASL-----RGHVAAVYQIAWSAD-SRLLVSGSSDS---TLKVWDVKAQKLATDLPGHADEVYAVDWSPDGQR----------VASGGKDKCLRIW 483          

Query:   25 MRIVKPIYINYQNPQKDQILTEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHI---DKKFH--ESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDK-NSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKE-------TKEEFLLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELGIPLTLDEMKQFFEKTYGSGF-----------VVDNSAISKSKNNAFIIPESSAVLKXXXXXXXXNHDRKSTSLHLLNEKKTGPNEQIICHTKTGKRRITPKFLSSLDDEDIEPDPAPSKRIYSPETIPEILVPNKSKEDENVLISNAVKVSSKFKSVLE---------EKFVKPDSPNIVSSS 1584
            M+++KP ++N+           I S+DIHP G KFAT G G   G + IWNM P+  +E E +EN PK+L     HL CVNCVRWS NG YLASG  D ++++W +        +     K    E +R    LR HS D++D+AWSPH  +L S SVDN ++IWN  KFPE  + L GH+  +KG+ WDPVG+Y+ASQ++DH++++WRT DW+ ET +    D+   +    RL+WSPDG  +V+    NN  PT Q+  RD W   +D VGH++ +   ++ P + + K+       T   +   A+GSKDRSLSVW T  +RPLVVI +LF  SI+D+SW +    ++ CS+DGS+AY+ F+ DELG PL+ +E     + TYG              V++N  + K +    +  +   +++ Q +  + N         L + +K    +Q+   T  G+RRITP  ++ LD  D     A    I    ++P  ++ ++S +    L SN    S   KS +E         E+    +S N+ SSS
Sbjct:    1 MKLLKPSWVNHNG-------KPIFSVDIHPDGTKFATGGQGQDSGKVVIWNMPPMLKEEDEKNENIPKMLCQMDNHLACVNCVRWSNNGAYLASGGDDKLIMVWKRSGYIGPSTVFGSSSKLANVEQWRCLSILRSHSGDVMDVAWSPHDAWLASCSVDNTVVIWNALKFPEIISTLRGHSGLVKGLTWDPVGKYIASQADDHSIKVWRTMDWQLETSITKPFDECGGTTHVLRLSWSPDGHYLVSAHAMNNSGPTAQIIERDGWKTNMDFVGHRKAVTVVKFNPKIFKKKQKNGSSTKTSCPYCCCAVGSKDRSLSVWLTCLKRPLVVIHELFDKSIMDISWTLNGLGILVCSMDGSVAYLDFSQDELGDPLSEEEKNNIHQSTYGKSLAITTEPQLPNTVIENPEMLKFQQRQQLQQDGEHMVQAQMEAPIHNMASMMNGESLEDIRKNLLKKQVETRTADGRRRITPLCIAQLDTGDF--STAFFNSIPISGSLPGSMMSSQSNQQLISLDSNTTSSSGALKSNVELVGNNTKPAEETANKESGNVSSSS 544          

Query: 2191 NNDQKLWEITQTKQISVMAHFKDKLFVGDVCGFLHSFYLKGGRIQAPFSLDSGLTSLVCDGRYLIAVTVRATLYIWSIAPFAIFLK-ESFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSNK----SEFWSVSKLSSKNLINKPLASMQSSESICDGPMKNLSS---IVKQELILDRLEIQVKLAESLHSCEEYKYWLLLWVRHLIEADKEVRVRDICQRFLGPIHTSTKSNWDPFILRYSKRELLKEILPLFALNLRLQRLYT 3018
            + + K WE   T +I   A  K+ + V      L  F   G RI  P  L S +++L C G Y++A+T  A L +W +    I +K ES   LL+  G+   +    ++  G   L+  +G ++ F+  ++ W  V +  +     +++ S        + + PLA +Q   S       +L +   +V++E  +  LE QV  A  L S +EY++WLL++ ++L+    E R+R++CQ  LGP+H S+ S W+  IL   KRELLKE+LPL   NLR QRL+T
Sbjct:  720 HREGKEWEAVLTSRIVAAAGSKEVVCVACEKRMLSIFSGSGRRIFPPIILPSPISTLQCTGSYVMALTAAAALSVWDVQNQNIIIKNESLQPLLS--GNDLTVSQTLLTKRGIPVLSLSNGKAYCFSPSLSTWSLVSDKQDSLAQCADYRSCMPSQDAVMCSGPLAIIQGRVSNAGRQAAHLFTMPHLVQKETTMAYLENQVAAALMLQSSQEYRHWLLIYAQYLVNEGFEQRLREVCQDLLGPVHRSSDSQWESRILGLWKRELLKELLPLIGQNLRFQRLFT 1001          

Query:   25 MRIVKPIYINYQNPQKDQILTEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKL----------NDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDK-NSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKETKE-------EFLLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELGIPLTLDEMKQFFEKTYGSGFVVDNSAISKSKNNAFII--PESSAVLKXXXXXXXXNHDRKST----SLHLLNEKKTGPN----------EQIICHTKTGKRRITPKFLSSLDDEDIEP 1401
            M+++KP ++++           I S+DIHP G KFAT G G+  G + IWNM P+  +E E +EN PK+L     HL CVNCVRWS NG YLASG  D +V++W +  L          N L ++     E +R    LR H+ D++D++WSPH  +L S SVDN I+IWN  KFPE    L GH   +KG+ WDPVG+Y+ASQ++DH+LR+WRT DW+ E  +     +   +    RL+WSPDG  +V+    NN  PT Q+  RD W   +D VGH++ +   ++ P + + K+           +   A+GSKDRSLSVW T  +RPLVVI DLF  SI+D+SW +    ++ CS+DG++AY+ F+ DELG PL+ +E     +  YG    + N   ++ + +  II  PE     + ++     N    +T    +   LN    G +          +Q+   T  G+RRITP  ++ LD  D  P
Sbjct:    1 MKLLKPSWVSHNG-------KPIFSVDIHPDGTKFATGGQGEDSGKVMIWNMAPVLKEEDEKNENVPKMLCQMDNHLACVNCVRWSNNGLYLASGGDDKLVMVWKRAALIGPSTVFGSSNKLANV-----EQWRCVTILRNHTGDVMDVSWSPHDVWLASCSVDNTIVIWNARKFPEMVTCLRGHTGLVKGLTWDPVGKYIASQADDHSLRVWRTVDWQMEANITKPFSECGGTTHVLRLSWSPDGQYLVSAHAMNNSGPTAQIVERDGWRTNMDFVGHRKAVTVVKFNPKIFKKKQKNGGSPKPSCPYCCCAVGSKDRSLSVWLTSLKRPLVVIHDLFDKSIMDISWTLTGLGMLVCSMDGTVAYLDFSLDELGDPLSEEEKNSIHQNIYGKSLAITN---TEPQLSTTIIENPEMLKYQQERRNSTQANSGPGATGSESATPKLNSVMNGESLEDIRKNLLKKQVETRTPDGRRRITPLCIAQLDTGDFSP 478          

Query: 2197 DQKLWEITQTKQISVMAHFKDKLFVGDVCGFLHSFYLKGGRIQAPFSLDSGLTSLVCDGRYLIAVTVRATLYIWSIAPFAIFLK-ESFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSNK----SEFWSVSKLSSKNLINKPLASMQSSESICDGPMKNLSSI---VKQELILDRLEIQVKLAESLHSCEEYKYWLLLWVRHLIEADKEVRVRDICQRFLGPIHTSTKSNWDPFILRYSKRELLKEILPLFALNLRLQRLYT 3018
            D + W       +   A   D + V      L  F   G R+     L +  ++L C   +++ +T  ATL +W +      +K ES + +L+  G    +    ++ +G   +   +G S+ F+  +  W  + + ++     ++F +        + + PLA+MQ            LSS    ++Q + L  LE Q+  A +L S +EY+YWLL++ R L+    E R+R++C+  LGP+H S  ++W+P  L   KR+LL+E+LP+   NLR QRL+T
Sbjct:  734 DGRDWNTLLPSSVLTAAGSSDVVAVASQDRMLSVFSSCGRRLLPAIQLATPASALHCSAHFVMVLTSGATLSVWDVHKQKALVKNESLLTILS--GAAVTVSQSMLTQQGVPVVGLSNGKSYCFSLSLETWTLIADTADSLVQCADFRNCLPNQDAPMSSGPLAAMQGRNFNAGRLASRLSSTPHHLQQSMTLAFLENQLASALTLQSAQEYRYWLLIYARFLVNEGSEYRLRELCKELLGPVHKSATTSWEPTTLGLRKRDLLREVLPVVGENLRFQRLFT 1013          

Query:   25 MRIVKPIYINYQNPQKDQILTEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHI---DKKFH--ESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDK-NSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKETKEE-------FLLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELGIPLTLDEMKQFFEKTYGSGFVVDNSAISKSKNNAFIIPESSAVLKXXXXXXXXNHDRKSTSLHLLNE----------------KKTGPNEQIICHTKTGKRRITPKFLSSLDDED 1392
            M+++KP ++N+           I S+DIHP G KFAT G G   G + IWNM P+  ++ E DEN PK+L     HL CVNCVRWS +G YLASG  D ++++W +        +     K    E +R    LR HS D++D+AWSPH  +L S SVDN ++IWN  KFPE  A L GH+  +KG+ WDPVG+Y+ASQ++D +L++WRT DW+ ET +    D+   +    RL+WSPDG  +V+    NN  PT Q+  R+ W   +D VGH++ +   ++ P + + K+           +   A+GSKDRSLSVW T  +RPLVVI +LF  SI+D+SW +    ++ CS+DGS+A++ F+ DELG PL+ +E  +  + TYG    +    +++++ +  +I E+  +LK Q++QQ    D+KS +   +                  +K    +Q+   T  G+RRITP  ++ LD  D
Sbjct:    1 MKLLKPTWVNHNG-------KPIFSVDIHPDGTKFATGGQGQDSGKVVIWNMSPVLQEDDEKDENIPKMLCQMDNHLACVNCVRWSNSGMYLASGGDDKLIMVWKRATYIGPSTVFGSSGKLANVEQWRCVSILRNHSGDVMDVAWSPHDAWLASCSVDNTVVIWNAVKFPEILATLRGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTLDWQLETSITKPFDECGGTTHVLRLSWSPDGHYLVSAHAMNNSGPTAQIIEREGWKTNMDFVGHRKAVTVVKFNPKIFKKKQKNGSSAKPSCPYCCCAVGSKDRSLSVWLTCLKRPLVVIHELFDKSIMDISWTLNGLGILVCSMDGSVAFLDFSQDELGDPLSEEEKSRIHQSTYGKSLAI----MTEAQLSTAVI-ENPEMLKYQRRQQQQQLDQKSAATREMGSATSVAGVVNGESLEDIRKNLLKKQVETRTADGRRRITPLCIAQLDTGD 473          

Query: 2191 NNDQKLWEITQTKQISVMAHFKDKLFVGDVCGFLHSFYLKGGRIQAPFSLDSGLTSLVCDGRYLIAVTVRATLYIWSIAPFAIFLKESFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSNK----SEFWSVSKLSSKNLINKPLASMQSSESICDGPMKNLSSI---VKQELILDRLEIQVKLAESLHSCEEYKYWLLLWVRHLIEADKEVRVRDICQRFLGPIHTSTKSNWDPFILRYSKRELLKEILPLFALNLRLQRLYT 3018
            N + K WE   T +I   A   D + V      L  F   G R+ +P  L S +++L C G Y++A+T  ATL +W +    + +KE  +H +    D T +  I ++  G   +    G ++ FN  ++ W  V +  +     ++F S        L + PLA +Q   S        L S+   V+QE  L  LE QV  A +L S  EY++WLL++ R+L+    E R+R+IC+  LGP+H ST S W+  ++   KRELLKE+LP+   NLR QRL+T
Sbjct:  724 NREGKEWETVLTSRILTAAGSCDVVCVACEKRMLSVFSTCGRRLLSPILLPSPISTLHCTGSYVMALTAAATLSVWDVHRQVVVVKEESLHSILAGSDMT-VSQILLTQHGIPVMNLSDGKAYCFNPSLSTWNLVSDKQDSLAQCADFRSSLPSQDAMLCSGPLAIIQGRTSNSGRQAARLFSVPHVVQQETTLAYLENQVAAALTLQSSHEYRHWLLVYARYLVNEGFEYRLREICKDLLGPVHYSTGSQWESTVVGLRKRELLKELLPVIGQNLRFQRLFT 1005          

Query:   25 MRIVKPIYINYQNPQKDQILTEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQK-------------KLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDK-NSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKE-----TKEE--FLLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELGIPLTLDEMKQFFEKTYG-----------SGFVVDNSAISK----------SKNNAFIIPESSAVLKXXXXXXXXNHDRKSTSLHLLNEKKTGPNEQIICHTKTGKRRITPKFLSSLDDED 1392
            M+++KP ++N+           I S+DIHP G KFAT G G   G + IWNM P+  +E E +EN PK+L     HL CVNCVRWS NG YLASG  D ++++W +              KL ++E         +R    LR HS D++D+AWSPH  +L S SVDN ++IWN  KFPE  A L GH+  +KG+ WDPVG+Y+ASQ++D +L++WRT DW+ ET +    D+   +    RL+WSPDG  +V+    NN  PT Q+  RD W   +D VGH++ +   ++ P + + K+     TK    +   A+GSKDRSLSVW T  +RPLVVI +LF  SI+D+SW +    ++ CS+DGS+A++ F+ DELG PL+ +E     + TYG           S  +++N  + K           + NA I   S A     +   ++N +       L + +K    +Q+   T  G+RRITP  ++ LD  D
Sbjct:    1 MKLLKPTWVNHNG-------KPIFSVDIHPDGTKFATGGQGQDSGKVVIWNMAPVLKEEDEKNENIPKMLCQMDNHLACVNCVRWSNNGVYLASGGDDKLIMVWKRAAYIGPSTVFGSSSKLTNVEQ--------WRCVSILRSHSGDVMDVAWSPHDAWLASCSVDNTVVIWNAVKFPEILATLKGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTMDWQLETSITKPFDECGGTTHVLRLSWSPDGHYLVSAHAMNNSGPTAQIIERDGWKTNMDFVGHRKAVTVVKFNPKIFKKKQKNGSSTKSSCPYCCCAVGSKDRSLSVWLTCLKRPLVVIHELFDKSIMDISWTLNGLGILVCSMDGSVAFLDFSQDELGDPLSEEEKSNIHQSTYGKSLAIMTEAQLSTTIIENPEMLKYQQRQQQQQAEQKNASIREASGAATTAPKVASMVNGE------SLEDIRKNLLKKQVETRTADGRRRITPLCIAQLDTGD 477          

Query: 2191 NNDQKLWEITQTKQISVMAHFKDKLFVGDVCGFLHSFYLKGGRIQAPFSLDSGLTSLVCDGRYLIAVTVRATLYIWSIAPFAIFLK-ESFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSNK----SEFWSVSKLSSKNLINKPLASMQSSESICDGPMKNLSS---IVKQELILDRLEIQVKLAESLHSCEEYKYWLLLWVRHLIEADKEVRVRDICQRFLGPIHTSTKSNWDPFILRYSKRELLKEILPLFALNLRLQRLYT 3018
            N + K WE   T +I   A   + + V      L  F   G R+  P  L++ +++L C G Y++ +T  ATL +W +    + ++ ES   +L+  G  T +  I ++  G   ++   G ++ FN  ++ W  V +  +     ++F S        L + PLA +Q   S        L S   +V+QE  L  LE Q+  A  L S  EY++WLL++ R+L+    E R+R++C+  LGP+H S  S W+  ++   KRELLKE+LP+   NL  QRL+T
Sbjct:  730 NREGKEWETVLTSRILTAAGSCEIVCVACEKRMLSVFSACGRRLLPPIILNTPISTLHCTGSYIMTLTTAATLSVWDVHKQTVIVRDESLQTILS--GSDTTVSQILLTQHGIPVMSMSDGKAYCFNPSLSTWNLVSDKQDSLAQCADFRSSLPSQEAMLCSGPLAVIQGRTSNSGRQAARLFSMPHLVQQETTLAYLENQIAAALMLQSSHEYRHWLLIYARYLVNEGFEYRLRELCKDLLGPVHYSRGSQWESTVMGLRKRELLKELLPVIGQNL-FQRLFT 1010          

Query:   25 MRIVKPIYINYQNPQKDQILTEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHI---DKKFH--ESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDK-NSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKE-----TKEE--FLLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELGIPLTLDEMKQFFEKTYGSGFVVDNSAISKSKNNAFIIPESSAVLKXXXXXXXXNHDRKSTSLH----------------LLNEKKTGPNEQIICHTKTGKRRITPKFLSSLDDEDI 1395
            M+++KP ++N+           I S+DIHP G KFAT G G   G + IWNM P+  ++ E DEN PK+L     HL CVNCVRWS +G YLASG  D ++++W +        +     K    E +R    LR HS D++D+AWSPH  +L S SVDN ++IWN  KFPE  A L GH+  +KG+ WDPVG+Y+ASQ++D +L++WRT DW+ ET +    D+   +    RL+WSPDG  +V+    NN  PT Q+  R+ W   +D VGH++ +   ++ P + + K+     TK    +   A+GSKDRSLSVW T  +RPLVVI +LF  SI+D+SW +    ++ CS+DGS+A++ F+ DELG PL+ +E  +  + TYG    +    +++++ +  +I E+  +LK Q++QQ    D+K+ +                  L + +K    +Q+   T  G+RRITP  ++ LD  D 
Sbjct:    1 MKLLKPTWVNHNG-------KPIFSVDIHPDGTKFATGGQGQDSGKVVIWNMSPVLQEDDEKDENIPKMLCQMDNHLACVNCVRWSNSGMYLASGGDDKLIMVWKRATYIGPSTVFGSSGKLANVEQWRCVSILRSHSGDVMDVAWSPHDAWLASCSVDNTVVIWNAVKFPEILATLRGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTLDWQLETSITKPFDECGGTTHVLRLSWSPDGHYLVSAHAMNNSGPTAQIIEREGWKTNMDFVGHRKAVTVVKFNPKIFKKKQKNGSSTKPSCPYCCCAVGSKDRSLSVWLTCLKRPLVVIHELFDKSIMDISWTLNGLGILVCSMDGSVAFLDFSQDELGDPLSEEEKSRIHQSTYGKSLAI----MTEAQLSTAVI-ENPEMLKYQRRQQQQQLDQKNATTRETSSASSVTGVVNGESLEDIRKNLLKKQVETRTADGRRRITPLCIAQLDTGDF 474          

Query: 2191 NNDQKLWEITQTKQISVMAHFKDKLFVGDVCGFLHSFYLKGGRIQAPFSLDSGLTSLVCDGRYLIAVTVRATLYIWSIAPFAIFLKESFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSNK----SEFWSVSKLSSKNLINKPLASMQSSESICDGPMKNLSSI---VKQELILDRLEIQVKLAESLHSCEEYKYWLLLWVRHLIEADKEVRVRDICQRFLGPIHTSTKSNWDPFILRYSKRELLKEILPLFALNLRLQRLYT 3018
            N + K WE   + ++   A   D + V      L  F   G R+  P  L S +++L C G Y++A+T  ATL +W +    + +KE  +H +    D T +  I ++  G   +    G ++ FN  ++ W  V +  +     ++F +        L + PLA +Q   S        L S+   V+QE  L  LE QV  A +L S  EY++WLLL+ R+L+    E R+R+IC+  LGP+H ST S W+  ++   KRELLKE+LP+   NLR QRL+T
Sbjct:  722 NREGKEWETVLSSRVLTAAGSCDVVCVACEKRMLSVFSTCGRRLLPPILLPSPISTLHCTGPYVMALTAAATLSVWDVHRQVVVVKEESLHSILSGSDMT-VSQILLTQHGIPVMNLSDGKAYCFNPSLSTWNLVSDKQDSLAQCADFRNSLPSQDAMLCSGPLAIIQGRTSNSGRQAARLFSVPHVVQQETTLAYLENQVAAALTLQSSHEYRHWLLLYARYLVNEGFEYRLREICKDLLGPVHCSTGSQWESTVVGLRKRELLKELLPVIGQNLRFQRLFT 1003          

Query:   25 MRIVKPIYINYQNPQKDQILTEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQK-------------KLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDK-NSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKETKEE-------FLLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELGIPLTLDEMKQFFEKTYGSGFVVDNSA---ISKSKNNAFIIPESSAVLKXXXXXXXXNHDRKSTSLHLLNE-----KKTGPNEQIICHTKTGKRRITPKFLSSLDDED--------IEPDPAPSKRIYSPETIPEIL-----VPN---KSKEDENVLISNAVKVSSKFKSVLEEKFVKPDSPNIVSSSEDRRDS-LNSLKIKTQRKDDKANDNKSSCGIDSKSPK-----KDEKSVDSISTKIGSSVEKSPKKDDKVFEMPTALVTKPKLLKDLESVPSNNDLKSTVNSRRSILYKDVVEKLNSEAVKPXXXXXXXXXXXXXXXESPKKIFRESKSVTEKRLFLSQSVLKHNYSLLCLLPGDHDHFVVKIISENGTGSKTPTSNQADPKVYKICVN---------------NNDQKLWEITQTKQISVMAHFKDKLFVGDVCGFLHSFYLKGGRIQAPFSLDSGLTSLVCDGRYLIAVTVRATLYIWSIAPFAIFLKESFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSNK----SEFWSVSKLSSKNLINKPLASMQSSESICDGPMKNLSS---IVKQELILDRLEIQVKLAESLHSCEEYKYWLLLWVRHLIEADKEVRVRDICQRFLGPIHTSTKSNWDPFILRYSKRELLKEILPLFALNLRLQRLYT 3018
            M+++KP ++N+           I SIDIHP G KFAT G G   G + IWNM P+  ++ E DEN PK+L     HL CVNCVRWS +G YLASG  D ++++W +              KL+++E         +R    LR HS D++D+AWSPH  +L S SVDN ++IWN  KFPE  A L GH+  +KG+ WDPVG+Y+ASQ++D +L++WRT DW+ ET +    D+   +    RL+WSPDG  +V+    NN  PT Q+  R+ W   +D VGH++ +   ++ P + + K+           +   A+GSKDRSLSVW T  +RPLVVI +LF  SI+D+SW +    ++ CS+DGS+A++ F+ DELG PL+ +E  +  + TYG    +   A    +  +N   +  +     +L Q+         +TS+ +  E     +K    +Q+   T  G+RRITP  ++ LD  D        I    + +  + S  + P++L      PN    SK     + +   K +   +SV ++      +P   S S     S +  +K    R  +++     +  + S +P      K++  V  I  +    +E S   D+KV       VTKP                S+++ R+  L  + VEK      K         + +S   +SP  +  E  +     L LS   L    +L   +PG    F +++ S              DP +Y    N               N + K WE   T +I   A   D + V      L  F   G R+  P  L S +++L C G Y++A+T  ATL +W +    + +KE  +H +    D T +  I ++  G   +    G ++ FN  ++ W  V +  +     ++F +        L + PLA +Q   S        L S   +V+QE  L  LE QV  A SL S  EY++WLL++ R+L+    E R+R+IC+  LGP+H ST S W+  ++   KRELLKE+LP+   NLR QRL+T
Sbjct:    1 MKLLKPTWVNHNG-------KPIFSIDIHPDGTKFATGGQGQDSGKVVIWNMSPVLQEDDEKDENIPKMLCQMDNHLACVNCVRWSNSGMYLASGGDDKLIMVWKRATYIGPSTVFGSSGKLSNVEQ--------WRCVSILRSHSGDVMDVAWSPHDAWLASCSVDNTVVIWNAVKFPEILATLRGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTLDWQLETSITKPFDECGGTTHVLRLSWSPDGHYLVSAHAMNNSGPTAQIIEREGWKTNMDFVGHRKAVTVVKFNPKIFKKKQKNGSSAKPSCPYCCCAVGSKDRSLSVWLTCLKRPLVVIHELFDKSIMDISWTLNGLGILVCSMDGSVAFLDFSQDELGDPLSEEEKSRIHQSTYGKSLAIMTEAQLSTAVIENPEMLKYQRRQQQQLDQKSAAARETGSATSVAVNGESLEDIRKNLLKKQVETRTADGRRRITPLCIAQLDTGDFSTAFFNSIPLSGSLAGTMLSSHSSPQLLPLDSSTPNSFGASKPSTEHMAAAGAKPTG--ESVGKDSVTATSAPAASSPSVLTTPSKIEPMKAFDSRFTERSKATSGTPALSSMTPTAVERLKEQNLVKEIRPR--DLLESSSDSDEKV------PVTKP----------------SSLSKRKLELEAETVEKKK----KGRPRKDSRLMPVSLSVQSPASLTAEKDT-----LCLSAPAL----ALKLPIPGPQRAFTLQVSS--------------DPSMYIEVENEVTAVGGVKLSRLKCNREGKEWETVLTSRILTAAGSCDIVCVACEKRMLSVFSTCGRRLLPPILLPSPISTLHCTGPYVMALTAAATLSVWDVHKQVVVVKEESLHSILAGSDMT-VSQILLTQHGIPVMNLSDGKAYCFNPSLSTWNLVSDKQDSLAQCADFRNSLPSQDAMLCSGPLAIIQGRTSNSGRQAARLFSMPHVVQQETTLAYLENQVAAALSLQSSHEYRHWLLIYARYLVNEGFEYRLREICKDLLGPVHYSTGSQWESTVVGLRKRELLKELLPVIGQNLRFQRLFT 1002          

Query:   25 MRIVKPIYINYQNPQKDQ-ILTEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHI------DKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIW-----NVDKFPEKTAILN---GHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCS-FQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKETKEE--FLLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELGIPLTLDEMKQFFEKTYGSGFVVD-----NSAISKSK---------------NNAFIIPESSAVLKXXXXXXX-----XNHDRKSTSLHLLNEKKTGPNEQIICHTKTGKRRITPKFLSSLD--DEDIEPD---PAPSKRIYS------PETIPEILVPNKSKEDENV----LIS------NAVKVSSKFKSV-----------LEEKFVK---------PDSPNIVSSSEDRR------------DSLNSLKIKTQRKDDKANDNKSSCGIDSKSPKKDEKSVDSISTKIGSSVEKSPKKDDKVFEMPTALVTKPKLLKDLESVPSNNDLKSTVNSRRSILYKDVVEKLNSE-AVKPXXXXXXXXXXXXXXXESPKKIFRESKSVTEKRLFLSQSVLKHNYSLLCLLPGDHDHFV-VKIISENGTGSKTPTSNQADPKVYKICVNNNDQKLWEITQTKQISVMAHFKDKLFVGDVCGFLHSFYLKGGRIQAPFSLD---------------------------------------------SGLTSLVCDGR-----YLIAVTVRATLYIW----------------SIAPFAIFLKE-SFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSNKSEFWSVSKLSSKNLINKPLASMQSSESICDGPMKNLSS---IVKQELILDR-LEIQVKLAESLHSCEEYKYWLLLWVRHLIEADKEVRVRDICQRFLGPIHTSTKSNWDPFILRYSKRELLKEILPLFALNLRLQRLY 3015
            MR++KP+++ + +  KDQ I   I S+DIHP G + AT G  D  G++ +WNM PIRN   E D + P+ L+   +H  CVNCVRWSP+G++LAS  +D V++IW +      +          KF E +R +  LRGH+ DI+DLAWS  G  L S SVDN +I+W          P + ++L    GH  F+KGV WDP+GRYLA+Q +D  + +WRTSDW+ E  +     K +  S   R++WS DGS I A    NNG PT +L +R NW   +D+VGH++H+ CARY P + R     E    + LALGSKDRS+SVWTT  RR LV I DLFT S+ DL+W  +  ELMACSLDG+++Y+ F   ELG P    E+ +   K YG   +       + AI   K               N + II E+   L LQQ Q +       +   +TS  L      GP++QI    K G+RRI PKFL  LD  DED  P    P  S +  S        T   I  P   +  E+     L+S      NA   S K   V           +E  F K         PD     SSS+D              D+++  +I T   +  A+  ++   +D ++    ++S + I  KIG    +  K+  ++F  P    T   + K   +  S +       +  S+    +   + SE AV+     + ++ ++ T + +P  I    + V+E ++             +C  P D    + +  ++    G++   +   +  + +I  +  D+ LWEI   K+++  ++  + + +GD+ G +   Y  GG +  P  LD                                             SG+      GR      L+A+     L IW                S + F  F+ E S   L T    ++   ++S    G   +    GSS+ F+    +W E+F+ SN +   SV+  ++++    PLAS Q           NL +        L++   L  Q   A+   S  EY+YWL  W RHL+E ++E ++R ICQ  +GP+ + ++++W P      K EL++E+L LFALN+RLQRLY
Sbjct:   32 MRLLKPLWVTHGSLSKDQNIDRPIYSLDIHPDGSRLATGGVIDTCGVVILWNMVPIRNPSLEMDASTPRKLFQMDSHQACVNCVRWSPSGRWLASAGMDKVIMIWTRTAATSRQTTVFGSKEQTKFTEHWRCSSVLRGHTGDIIDLAWSQDGRKLASASVDNNVIVWCRLSTATGAAPGQFSLLTTLRGHRGFVKGVAWDPIGRYLATQGDDVAVNVWRTSDWQIEANIKKPFAKATGQSQVMRISWSLDGSTIAAPHAINNGFPTAKLIDRTNWMPSLDLVGHRKHVTCARYNPNVFRKVTNGESHSLVCLALGSKDRSVSVWTTAARRALVAIHDLFTNSVCDLTWSADGQELMACSLDGTVSYMCFKSSELGTPWATSELVRLHHKAYGQSLLEKFDPEASEAIGLPKSVCTAGAGRKPSGNLNQSDIILETPEALALQQTQAVICKRLKENAESNTSSSLTRPPPAGPSKQIETRGKDGRRRIIPKFLGHLDAPDEDSNPQFSSPPQSAQQASRSPNQTQSTSAGIRAPTTPRPAESTSTRSLLSHALSSPNATTTSPKASGVANRTPVQEALRMECNFSKTQELSKNSSPDKNERCSSSKDTELPKPPSCVTIAVDTVSQPQITTASSESGASRKRAVSDVDMET--AVDQSGEEIRRKIG---RQKKKRRVRLFLEPDEESTSAVVDKKAAATHSKSSASGDNTANTSLPKLKIATAVESETAVRAFTSESRANGTVPTHNRTPFLINTPDQLVSETKI-----------KFVCSHPVDGPILMELSSVTSPTVGTRAAPALPENVGINRISASRGDRPLWEIVSEKRLTAYSYTDNLVSLGDLDGRIRLLYSTGGCLCPPIMLDSPIHLLALSSLDSANDPPEPETGKTANNPTSLSRLHTVVSGGAPVSGVPGSQTTGRNTNQYRLVALCQSGRLTIWHLNVPAVGFSSTSILYSPSVFPQFVVECSLCDLFTT--SQSAYSSMSFGPNGQPVVHKRDGSSYMFHIEGRMWLEMFDGSNPTRC-SVALTTARSCPPGPLASCQLLTKTIGATSDNLKASDNPTNHRLVMQNFLASQTNSAKIFGSSAEYRYWLTRWFRHLVEDNEEEQLRSICQDLIGPVFSGSRTSWQPVFKGIGKHELVRELLTLFALNMRLQRLY 1178          

Query:   25 MRIVKPIYINYQNPQKDQILTEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHI---DKKFH--ESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDK-NSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKETKEE-------FLLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELGIPLTLDEMKQFFEKTYGSGFVV------------------------DNSAISKSKNNAFIIPESSAVLKXXXXXXXXNHDRKSTSLHLLNEKKTGPNEQIICHTKTGKRRITPKFLSSLDDEDIEPDPAPSKRIY-SPETIPEILVPNKSKEDENVLISNAVKVSSKFKSVLEEKFVKPDSPNIVSSSEDRRDSLNSLKIKTQRKDDKANDNKSSCGIDSKSPKKDEKSVDSISTKIGSSVEKSPKKDDKVFEMPTALVTKPKLLKDLESVPSNNDLKSTVNSRRSILYKDVVEKL--NSEAVKPXXXXXXXXXXXXXXXESPKKIFRESKSVTEKRLFLSQSVLKHNYSLLCLLPGDHDHFVVKIISENGT--GSKTPTSNQADPKVYKI-CVNNNDQKLWEITQTKQISVMAHFKDKLFVGDVCGFLHSFYLKGGRIQAPFSLDSGLTSLVCDGRYLIAVTVRATLYIWSIAPFAIFLK-ESFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSNK----SEFWSVSKLSSKNLINKPLASMQSSESICDGPMKNLSSI---VKQELILDRLEIQVKLAESLHSCEEYKYWLLLWVRHLIEADKEVRVRDICQRFLGPIHTSTKSNWDPFILRYSKRELLKEILPLFALNLRLQRLYT 3018
            M+++KP ++++           I S+DIHP G KFAT G G+  G + IWNM P+  +E E +EN  K+L     HL CVNCVRWS NG+ LASG  D +V++W +        +     K    E +R    LR H+ D++D+AWSPH  +L S SVDN I+IWN  KFPE    L GH   +KG+ WDPVG+Y+ASQ++DH+L++WRT DW+ +  +     +   +    RL+WSPDG  +V+    NN  PT Q+  RD W   +D VGH++ +   ++ P + + K+           +   A+GSKDRSLSVW T  +RPLVVI DLF  SI+D+SW +    ++ CS+DG++AY+ F+ DELG PL  +E     +  YG    +                         NSA + S   A   PESSA          LN      SL   + +K    +Q+   T  G+RRITP  ++ LD  D  P    S  I  S  ++   L P  S +      S     S   K   +     P   N     ED  D + S  + T      A+  +    +DS+  ++  K+   ++  I S+   +P   ++    P   VT  K  K  E   S+++ K    ++     K   E L    E ++           ++     P   F ++    E+      +       L    P     F +++  E       +   S  A  K+ ++ C  + D + W       + V A   D L V      L  F   G R+     L +  ++L C   Y++ +T  ATL +W +      +K ES + +L+  G  T +    ++ +G   +   +G S+ F+  +  W  + + S+     ++F S        + + PLA MQ            LSS    ++Q + L  LE Q+  A +L S +EY+YWLL++ R L+    E R+R++C+  LGP+H S  ++W+P  L   KRELL+E+LP+   NLR QRL+T
Sbjct:    1 MKLLKPSWVSHNG-------KPIFSVDIHPDGTKFATGGQGEDSGKVMIWNMAPVLREEDEKNENISKMLCQMDNHLACVNCVRWSNNGQCLASGGDDKLVMVWKRAAFIGPSTVFGSSSKLANVEQWRCVTILRNHTGDVMDVAWSPHDVWLASCSVDNTIVIWNARKFPEMITTLRGHTGLVKGLTWDPVGKYIASQADDHSLKVWRTVDWQMDANITKPFSECGGTTHVLRLSWSPDGQYLVSAHAMNNSGPTAQIVERDGWKTNMDFVGHRKAVTVVKFNPKIFKKKQKNGSSPKPSCPYCCCAVGSKDRSLSVWLTSLKRPLVVIHDLFDKSIMDISWTLTGLGMLVCSMDGTVAYLDFSLDELGDPLNEEEKNSIHQNIYGKSLAITSPEAQLSTTIIENPEILKYQQERQNSAQANSGPGA-AAPESSA--------PKLNSVMNGESLE--DIRKNLLKKQVETRTADGRRRITPLCIAQLDTGDFSPALFNSVPILPSGSSMSSQLTPQLSSDS-----SPGQASSMGLKPTHDPMLTSPPPNNTAKPMEDNNDGVKSSLLLT-----SASKIEPMKALDSRFTER-SKATPGVTAAISSTAGLTPLDSNR----PKDGVTAQKEAKTKEETSSDSEDKMAAINKNLTFGKRKPELLLDGREVLEKRKKGRPRKDKMAASMAQP---FTQTTPPAEREPSRVVAPPAPVAVLKLPTPSTQKAFSLQVSMEPSVFLEVENEVSMVAGSKLSQLRC--SRDGRDWNTLLPSSVVVAAGSSDILAVACEDRMLSVFSSCGRRLLPAIQLGTPASALHCSAHYVMVLTAGATLSVWDVQKQKALVKNESLLTVLS--GADTTVSQSLLTQQGVPVIGLSNGKSYCFSSSLETWTLIADKSDSLVQCADFRSCLPSHDTPVSSGPLAVMQGRNLNAGRLASRLSSTPHHLQQSMTLAFLENQLASALTLQSAQEYRYWLLIYARFLVNEGSEYRLRELCKELLGPVHKSAATSWEPTTLGLRKRELLREVLPVIGENLRFQRLFT 1009          

Query:   25 MRIVKPIYINYQNPQKDQILTEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHI---DKKFH--ESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDK-NSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKETKEE-------FLLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELGIPLTLDEMKQFFEKTYGSGFVV------------------------DNSAISKSKNNAFIIPESSAVLKXXXXXXXXNHDRKSTSLHLLNEKKTGPNEQIICHTKTGKRRITPKFLSSLDDEDIEPDPAPSKRIY-SPETIPEILVPNKSKEDENVLISNAVKVSSKFKSVLEEKFVKPDSPNIVSSSEDRRDSLNSLKIKTQRKDDKANDNKSSCGIDSKSPKKDEKSVDSISTKIGSSVEKSPKKDDKVFEMPTALVTKPKLLKDLESVPSNNDLKSTVNSRRSILYKDVVEKL--NSEAVKPXXXXXXXXXXXXXXXESPKKIFRESKSVTEKRLFLSQSVLKHNYSLLCLLPGDHDHFVVKIISENGT--GSKTPTSNQADPKVYKI-CVNNNDQKLWEITQTKQISVMAHFKDKLFVGDVCGFLHSFYLKGGRIQAPFSLDSGLTSLVCDGRYLIAVTVRATLYIWSIAPFAIFLK-ESFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSNK----SEFWSVSKLSSKNLINKPLASMQSSESICDGPMKNLSSI---VKQELILDRLEIQVKLAESLHSCEEYKYWLLLWVRHLIEADKEVRVRDICQRFLGPIHTSTKSNWDPFILRYSKRELLKEILPLFALNLRLQRLYT 3018
            M+++KP ++++           I S+DIHP G KFAT G G+  G + IWNM P+  +E E +EN  K+L     HL CVNCVRWS NG YLASG  D +V++W +        +     K    E +R    LR H+ D++D+AWSP   +L S SVDN I+IWN  KFPE    L GH   +KG+ WDPVG+Y+ASQ++DH+L++WRT DW+ +  +     +   +    RL+WSPDG  +V+    NN  PT Q+  RD W   +D VGH++ +   ++ P + + K+           +   A+GSKDRSLSVW T  +RPLVVI DLF  SI+D+SW +    ++ CS+DG++AY+ F+ DELG PL  +E     +  YG    +                         NSA + S   A   PESSA          LN      SL   + +K    +Q+   T  G+RRITP  ++ LD  D  P    S  I  S  ++   L P  S +      S     S   K   +     P   N     ED  D + S  + T      A+  +    +DS+  ++  K+   ++  I S+   +P   ++    P   VT  K  K  E   S+++ K    ++     K   E L    E ++           ++     P   F +     E+      +       L    P     F +++  E       +   S  A  K+ ++ C  + D + W       + V A   D L V      L  F   G R+     L +  ++L C   Y++ +T  ATL +W +      +K ES + +L+  G  T +    ++ +G   +   +G S+ F+  +  W  + + S+     ++F S        + + PLA MQ            LSS    ++Q + L  LE Q+  A +L S +EY+YWLL++ R L+    E R+R++C+  LGP+H S  ++W+P  L   KRELL+E+LP+   NLR QRL+T
Sbjct:    1 MKLLKPSWVSHNG-------KPIFSVDIHPDGTKFATGGQGEDSGKVMIWNMAPVLREEDEKNENISKMLCQMDNHLACVNCVRWSNNGLYLASGGDDKLVMVWKRAAFIGPSTVFGSSSKLANVEQWRCVTILRNHTGDVMDVAWSPRDVWLASCSVDNTIVIWNARKFPEMITTLRGHTGLVKGLTWDPVGKYIASQADDHSLKVWRTVDWQMDANITKPFSECGGTTHVLRLSWSPDGQYLVSAHAMNNSGPTAQIVERDGWKTNMDFVGHRKAVTVVKFNPKIFKKKQKNGSSPKPSCPYCCCAVGSKDRSLSVWLTSLKRPLVVIHDLFDKSIMDISWTLTGLGMLVCSMDGTVAYLDFSLDELGDPLNEEEKNSIHQNIYGKSLAITSTEAQLSTTIIENPEILKYQQERQNSAQANSGPGA-AAPESSA--------PKLNSVMNGESLE--DIRKNLLKKQVETRTADGRRRITPLCIAQLDTGDFSPALFNSVPILPSGSSMSSQLTPQLSSDS-----SPGQASSMGLKPTHDPMLTSPPPNNTAKPMEDNNDGVKSSLLLT-----SASKIEPMKALDSRFTER-SKATPGVTAAISSTAGLTPLDSNR----PKDGVTAQKEAKTKEETSSDSEDKMAAINKNLTFGKRKPELLLDGREVLEKRKKGRPRKDKMAASMAQP---FTQITPPAEQEPSRVVAPPAPVAVLKLPTPSTQKAFSLQVSMEPSVFLEVENEVSMVAGSKLSQLRC--SRDGRDWNTLLPSSVVVAAGSSDILAVACEDRMLSVFSSCGRRLLPAIQLGTPASALHCSAHYVMVLTAGATLSVWDVQKQKALVKNESLLTVLS--GADTTVSQSLLTQQGVPVIGLSNGKSYCFSSSLETWTLIADKSDSLVQCADFRSCLPSHDTPVSSGPLAVMQGRNLNAGRLASRLSSTPHHLQQSMTLAFLENQLASALTLQSAQEYRYWLLIYARFLVNEGSEYRLRELCKELLGPVHKSAATSWEPTTLGLRKRELLREVLPVIGENLRFQRLFT 1009          

Query:   25 MRIVKPIYINYQNPQKDQILTEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHI---DKKFH--ESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDK-NSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKETKEE-------FLLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELGIPLTLDEMKQFFEKTYGSGFVVDNSAISKS---------------KNNAFIIPESSAVLKXXXXXXXXNHDRKSTSLHLLNEKKTGPNEQIICHTKTGKRRITPKFLSSLDDEDIEPDPAPSKRIYSPETIPEILVPNKSKEDENVLISNAVKVSSKFKSVLEEKFVKPDSPNIVSSSEDRRDSLN-SLKIKTQRKDDKANDNKSSCGIDSKSPKKDEKSVDSISTKIGSSVEKSPKKDDKVFEMPTALVTKPKLLKDLESVPSNNDLKSTVNSRRSILYKDVVEKL--NSEAVKPXXXXXXXXXXXXXXXESPKKIFRESKSVTEKRLFLSQSVLKHNYSLLCLLPGDHDHFVVKIISENGT--GSKTPTSNQADPKVYKI-CVNNNDQKLWEITQTKQISVMAHFKDKLFVGDVCGFLHSFYLKGGRIQAPFSLDSGLTSLVCDGRYLIAVTVRATLYIWSIAPFAIFLK-ESFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSNK----SEFWSVSKLSSKNLINKPLASMQSSESICDGPMKNLSSI---VKQELILDRLEIQVKLAESLHSCEEYKYWLLLWVRHLIEADKEVRVRDICQRFLGPIHTSTKSNWDPFILRYSKRELLKEILPLFALNLRLQRLYT 3018
            M+++KP ++++           I S+DIHP G KFAT G G+  G + IWNM P+  +E E +EN PK+L     HL CVNCVRWS NG YLASG  D +V++W +  L     +     K    E +R    LR H+ D++D+AWSPH  +L S SVDN I++WN  KFPE    L GH   +KG+ WDPVG+Y+ASQ++DH+L++WRT DW+ E  +     +   +    RL+WSPDG  +V+    NN  PT Q+  RD W   +D VGH++ +   ++ P + + K+           +   A+GSKDRSLSVW T  +RPLVVI DLF  SI+D+SW +    ++ CS+DG++AY+ F+ DELG PL  +E     +  YG    + N+    S               + N+     ++A +  +     +N      SL   + +K    +Q+   T  G+RRITP  ++ LD  D       S  I    +     +P +   D +    +++ + +    VL      P   ++  + ED  D +  SL + +  K +          +DS+  ++  K+   +++ I S+   +P       + P   V+ PK LK  E   S+++ K    ++     K   E L    E V+           ++T    P   F +  +  E+      +       L    P     F +++  E       +   S  A  K+ ++ C  + D + W       +   A   D L V      L  F   G R+     L + +++L C   +++A+T  A L +W +      +K ES + +L+  G  T +    ++ +G   +   +G +F F+  +  W  + +  +     ++F          + + PLA++Q            LSS    ++Q + L  LE Q+  A +L S +EY+YWLL + R L+    E R+R++C+  LGP+H S  ++W+   L   KRELL+E+LP+   NLR QRL+T
Sbjct:    1 MKLLKPSWVSHNG-------KPIFSVDIHPDGTKFATGGQGEDSGKVMIWNMAPVLREEDEKNENVPKMLCQMDNHLACVNCVRWSNNGLYLASGGDDKLVMVWKRAALIGPSTVFGSSSKLANVEQWRCVTILRNHTGDVMDVAWSPHDIWLASCSVDNTIVVWNARKFPEMVTCLRGHTGLVKGLTWDPVGKYIASQADDHSLKVWRTVDWQMEANITKPFSECGGTTHVLRLSWSPDGQYLVSAHAMNNSGPTAQIVERDGWKTNMDFVGHRKAVTVVKFNPKIFKKKQKNGSSPKPGCPYCCCAVGSKDRSLSVWLTSLKRPLVVIHDLFDKSIMDISWTLTGLGMLVCSMDGTVAYLDFSLDELGDPLNEEEKNSIHQNIYGKSLAITNTEAQLSTTIIENPEMLKYQQERQNSTQANPAAASVGSESSAPKVNSVMNGESLE--DIRKNLLKKQVETRTADGRRRITPLCIAQLDTGDFSLALFNSAPILPSGSSMSNQLPPQLNSDSSPGQPSSLGLKTHQDGVL----TSPPPNSVGKALEDNSDGMKPSLLLTSASKIEPMK------ALDSRFTER-SKATPGVTSAIASTAGLTP------LDRPKDTVSVPKDLKTKEDTSSDSEDKIGAVNKNLAFGKRKPELLMDGGEVVEKKKKGRPRKDKMATPISQP---FLQVTTPPERDSSRVAAPPAPVAVLKLPTPSTQKAFSLQVSMEPAVFLEVENEVSMVAGSKLSQLRC--SKDGRNWNTLLPSSVVTAAGSSDVLAVACEDRMLSVFSCCGRRLLPAIQLTTPISALHCSAHFVMALTAGAGLSVWDVHKQKALVKNESLLTVLS--GADTTVSQSMLTQQGVPVIGLSNGKTFCFSSSLETWTLIADRGDSLVQCADFRGCLPSHDAPVSSGPLAAIQGRNINAGRLASRLSSTPHHLQQSMTLAFLENQLASALTLQSSQEYRYWLLTYARFLVNEGSEYRLRELCKELLGPVHKSAATSWEATTLGLHKRELLREVLPVVGENLRFQRLFT 1007          

Query:  451 PHGTYLCSGSV---DNRIIIWNV-----------DKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTS----------DWKQETKLCDEIDKNSSCSFQ-------------RLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKETKEE-------FLLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELGIPLTLDEMKQFFEKTYG-----------SGFVVDNSAISKSKNNAFIIPESSAVLKXXXXXXXXNHDRKSTSLHLLNEKKTGPNEQIICHTKTGKRRITPKFLSSLDDEDIEPDPAPSKRIYSPETIPEILVPNKSKE 1476
            P GT   +G       +++IWN+           +  P+    ++ H + +  V W   G  LAS  +D  + +W+ +             + ++   E++++SS S               RL+WSPDG  +V+    NN  PT Q+  RD W   +D VGH++ +   ++ P + + K+           +   A+GSKDRSLSVW T  +RPLVVI DLF  SI+D++W +    ++ CS+DG++A++ F+ DELG PL  +E     +  YG           S  +++N  + K +      P SS       + Q            L + +K    +Q+   T  G+RRITP  ++ LD  D  P    S  I    ++   L P  S +
Sbjct:   23 PDGTKFATGGQGEDSGKVVIWNMAPVLRDEDEKNENIPKLLCQMDNHLACVNCVRWSNNGLCLASGGDDKLVMVWKKALITLSKSFSVTGLKHSRCVSELEQHSSISITGITELCGGTTHVLRLSWSPDGQYLVSAHAMNNSGPTAQIIERDGWKTNMDFVGHRKAVTVVKFNPKIFKKKQRNGSAPKPSCPYCCCAVGSKDRSLSVWLTSLKRPLVVIHDLFDKSIMDITWTLNGLGMLVCSMDGTVAFLDFSQDELGDPLNEEEKNAIHQNIYGKSLAITMDTQLSSTIIENPEMLKYQQERRAAPTSSGAQGASLENQTPKLTNVVNGESLEDIRKNLLKKQVETRTADGRRRITPLCIAQLDTGDFSPALFNSVPILPGSSVAPQLTPQLSSD 419          

Query: 2191 NNDQKLWEITQTKQISVMAHFKDKLFVGDVCGFLHSFYLKGGRIQAPFSLDSGLTSLVCDGRYLIAVTVRATLYIWSIAPFAIFLKESFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSNK----SEFWSVSKLSSKNLINK--PLASMQSSESICDGPMKN-LSSI---VKQELILDRLEIQVKLAESLHSCEEYKYWLLLWVRHLIEADKEVRVRDICQRFLGPIHTSTKSNWDPFILRYSKRELLKEILPLFALNLRLQRLYT 3018
            + D + W+     +I+V+    D + V      L  +   G R+     L + +++L C G +++A+T  ATL +W++      +K   ++ +    D T + +  ++ +G   +   +G SF F+  +  W  + +  +     ++F +   +S+++ +    PLA+ Q   S+  G + + LSS    ++Q + L  LE Q+  A  L S  EY++WLL++ R ++    E R+R++C+  LGP+H S+ S+W+P +L   KR++L E+LP+   NLR QRL+T
Sbjct:  635 SRDGREWDAVLPSRIAVVTGSSDVVAVACEDRTLSIYSSCGRRLLPSIMLPAPISALHCSGFFVMALTASATLSVWNVQKLTAVVKNESLNSILLGSDAT-VSSSMLTDQGVPVVGLSNGKSFCFSSSMETWNLIADKQDALVQCADFRNC--VSAQDALGSVGPLATTQG-RSLSAGRLASRLSSTPHHLQQGMTLAFLEQQLSSALVLRSSSEYRHWLLIYTRFIVNEGYEHRLRELCKDLLGPVHKSSTSSWEPTVLGLRKRDVLAEVLPVIGQNLRFQRLFT 916          

Query:   25 MRIVKPIYINYQNPQKDQILTEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQK--------KLNDLEH------IDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDN------RII---IW--NVDKFPEKTAI-LNGHNSFI------KGVCWDPVGRY--LASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDG 729
            M+++KP ++++           I S+DIHP G KFAT G G+  G + IWNM P+   E E +EN PK+L     HL CVNCVRWS NG  LASG  D +V++W +          +  L+H      +++    S     +L G +  ++ L+WSP G YL S    N      +II    W  N+D    + A+ +   N  I       G    P   Y   A  S+D +L +W TS  +    + D  DK    S   +TW+ +G
Sbjct:    1 MKLLKPSWVSHNG-------KAIFSVDIHPDGTKFATGGQGEDSGKVVIWNMAPVLRDEDEKNENIPKLLCQMDNHLACVNCVRWSNNGLCLASGGDDKLVMVWKKALITLSKSFSVTGLKHSRCVSELEQHSSISITGITELCGGTTHVLRLSWSPDGQYLVSAHAMNNSGPTAQIIERDGWKTNMDFVGHRKAVTVVKFNPKIFKKKQRNGSAPKPSCPYCCCAVGSKDRSLSVWLTSLKRPLVVIHDLFDK----SIMDITWTLNG 258          

Query:  250 HLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLND-----------LEHIDKKFH-ESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCS-----------------FQRLTWSPDGSNIVATG----TSNNGAPTCQLYNRDNWSKGVDMVGHKQHII-----CARYFPTLLRSKETKEEF-------------LLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELGIPL 1104
            H K VN VR+SP+ + LASG  DA +++W   KLND            E  D + + ES+     LRGH  D+ D++W+  G +L SGSVDN  I+W+V K  +K  I N H S+++GV WDP+G+Y+++ S D  +R++ T   +++  +  ++   S+                   F+RLT++PDGS ++A         N   T  +++R ++ + V  +            C  YF   LR+K+ ++               L+ A+ S+D S+  + T +  P   +S++  +++ DLSW  +   L   S DG  ++V F + ELG PL
Sbjct:   65 HTKAVNVVRFSPSSELLASGGDDAAILLW---KLNDSKEPEQTPTFIQEDEDAQLNKESWNVVKTLRGHIEDVYDISWTSDGNFLVSGSVDNTAIMWDVQKG-QKMCIFNDHKSYVQGVAWDPLGQYISTLSCDRVMRVYSTHT-RKKAYIVSKMTSGSAAEGEVKNYRMFHDDSMRSFFRRLTFTPDGSFLLAPAGCVEAGENVTNTTYVFSRKSFKRPVAHLPCPAKATLAVRCCPVYF--ELRTKKAEDGSVQPLPNAFQLPYRLVFAVASED-SIFFYDTQQTLPFGYVSNIHYHTLSDLSWSHDGSFLAVSSTDGYCSFVSFDELELGTPL 392          

Query:  250 HLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVG-----RYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDG 729
            H + V  V +SP GKYLASGS D  V  W           D      + +A   RGH++ ++ +AWSP G  L SG  +++I++W+     +    L GH  +I  +CW+P+      RYLAS S+D ++RIW T         CD+I    + S   + W  DG
Sbjct:  104 HTEAVISVAFSPTGKYLASGSGDTTVRFW-----------DLTTETPHHTA---RGHTHWVLSIAWSPDGKKLASGCKNSQILLWDPVTGQQIGKALTGHTKWITWLCWEPLHLNPECRYLASSSKDCSVRIWDTV-----LGRCDKILTGHTQSVTCVKWGGDG 249          

Query:  250 HLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILN----GHNSFIKGVCWDPVGRYLASQSEDHTLRIWR 636
            H   VN V +SP+ + LAS S D  + IW           D K  +   S   LRGH   +  +AWS     L SGS D+ + +W+V     KT  LN    GH   +  V W P G+ +AS  +D  LRIWR
Sbjct:  362 HQALVNEVLFSPDTRLLASASFDKSIKIW-----------DGKTGKYLTS---LRGHVAAVYQVAWSADSRLLVSGSSDSTLKVWDV-----KTGKLNVDLPGHADEVFAVDWSPDGQRVASGGKDKCLRIWR 475          

Query:  217 NCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFH--------ESY---RSAFQLRGHSYDIVDLAWS-----------------PHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKETKEEFLLLALGSKDRSLSVW 942
             C KIL     H + V CV+W  +G  L + S D  + +W  K       +    H          Y     AF+    + ++ DL  S                      L SGS D  + +WN  +  +  A L GH + +  V + P  R LAS S D +++IW     K  T L     +    +  ++ WS D S ++ +G+S++   T ++++       VD+ GH   +    + P   R          +A G KD+ L +W
Sbjct:  228 RCDKILTG---HTQSVTCVKWGGDG-LLYTSSQDRTIKVWRAKDGVQCRTLQGHAHWVNTLALSTDYVLRTGAFEPATATVNLQDLTGSLDEIKERALKRYNKVRGEGPERLVSGSDDFTLFLWNPAEEKKPVARLTGHQALVNEVLFSPDTRLLASASFDKSIKIWDGKTGKYLTSL-----RGHVAAVYQVAWSAD-SRLLVSGSSDS---TLKVWDVKTGKLNVDLPGHADEVFAVDWSPDGQR----------VASGGKDKCLRIW 474          

Query:   91 ICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAW-----SPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSD 645
            + S+   P+GK  A SG GD    +  W++        ET        +T   H   V  + WSP+GK LASG  ++ +++W           D    +    A  L GH+  I  L W     +P   YL S S D  + IW+         IL GH   +  V W   G  L + S+D T+++WR  D
Sbjct:  108 VISVAFSPTGKYLA-SGSGDT--TVRFWDL------TTETPH------HTARGHTHWVLSIAWSPDGKKLASGCKNSQILLW-----------DPVTGQQIGKA--LTGHTKWITWLCWEPLHLNPECRYLASSSKDCSVRIWDT-VLGRCDKILTGHTQSVTCVKWGGDG-LLYTSSQDRTIKVWRAKD 267          

Query:  109 HPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEK--TAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSD 645
            +P G   A S GGD+   + IW         KE D    K + +D  H + V  V WSP G YLAS S DA   IW +KK +D E +             L GH  ++  +AW+P G  L + S D  + IW VD+  E    +++N H   +K V W P    LAS S D+ + I++  D
Sbjct:   25 NPKGSLLA-SCGGDR--AVRIWG--------KEGDSWECKSVLSD-GHQRTVRKVAWSPCGNYLASASFDATTCIW-KKKNDDFECL-----------TVLEGHENEVKCVAWAPSGNMLATCSRDKSVWIWEVDEEDEYECVSVVNSHTQDVKHVVWHPTQELLASASYDNKVCIYKEED 181          

Query:  271 VRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLR-GHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNV--DKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNR--DNWSKGVDMVGHKQHIICARYFPTLLRSKETKEEFLLLALGSKDRSLSVW------------TTLRRRPLVVISDLFTYSIVDLSWYVEKFELM-ACSLDG 1056
            V W+P G  LAS   D  V IW             K  +S+     L  GH   +  +AWSP G YL S S D    IW    D F E   +L GH + +K V W P G  LA+ S D ++ IW   +  ++   C  +  + +   + + W P    ++A+ + +N    C +Y    D+W     + GH   +    + P   R          LA  S DR++ +W            +T   +    +S   + ++ D++W      L  AC  DG
Sbjct:   22 VAWNPKGSLLASCGGDRAVRIW------------GKEGDSWECKSVLSDGHQRTVRKVAWSPCGNYLASASFDATTCIWKKKNDDF-ECLTVLEGHENEVKCVAWAPSGNMLATCSRDKSVWIWEVDE--EDEYECVSVVNSHTQDVKHVVWHPT-QELLASASYDN--KVC-IYKEEDDDWECRATLEGHTSTVWSLSFDPEGHR----------LASCSDDRTVKIWKECTPGDGEGDGSTDTWKCACTLSGFHSRTVYDVAWDRLTGALATACGDDG 272          

Query:  196 KEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIW-NVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWR 636
            K+K  D  C  +L     H   V CV W+P+G  LA+ S D  V IW          +D++  + Y     +  H+ D+  + W P    L S S DN++ I+   D   E  A L GH S +  + +DP G  LAS S+D T++IW+
Sbjct:   89 KKKNDDFECLTVLEG---HENEVKCVAWAPSGNMLATCSRDKSVWIW---------EVDEE--DEYECVSVVNSHTQDVKHVVWHPTQELLASASYDNKVCIYKEEDDDWECRATLEGHTSTVWSLSFDPEGHRLASCSDDRTVKIWK 222          

Query:  235 YTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVAT 747
            +T   H K ++ V++SPNG++LAS S D ++ IW           D KF +S      L GH   I D+AWSP    L S S D  + IW++    +    L GH++++    ++P    + S S D ++RIW     K    L    D  S+  F R     DGS IV++
Sbjct:   36 FTLAGHTKAISSVKFSPNGEWLASSSADKLIKIW--------GSFDGKFEKS------LSGHKLGISDVAWSPDSNLLVSASDDKTLKIWDMGS-GKCLKTLKGHSNYVFCCNFNPQSNLVVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNR-----DGSLIVSS 186          

Query:  391 YRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIW-NVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGT 753
            Y   F L GH+  I  + +SP+G +L S S D  I IW + D   EK+  L+GH   I  V W P    L S S+D TL+IW     K    L    +    C+F         SN+V +G+
Sbjct:   32 YTLKFTLAGHTKAISSVKFSPNGEWLASSSADKLIKIWGSFDGKFEKS--LSGHKLGISDVAWSPDSNLLVSASDDKTLKIWDMGSGKCLKTLKGHSNYVFCCNFN------PQSNLVVSGS 145          

Query:  271 VRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNV-DKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNR--DNWSKGVDMVGHKQHIICARYFPTLLRSKETKEEFLLL-----ALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTD-----DELGIPLTLDEMKQFFE 1134
            V WSP+G  +AS   D  V +W ++    +           RS      H   + ++AWSP GT L S S D    +W+  D   E TA L GH + +KGV W P G  LA+ S D ++ IW   +  +E   C  +  + +   + + W P+ S ++A+ + +N   + +LY    D+WS    + GH+  +    +  T  R     ++  +      A  S    + V        +  +S   T  I D+SW         C L G+IA     D     +E  +P    +  +F+E
Sbjct:   21 VAWSPSGALIASCGGDKTVRVWGREGDGWV----------CRSVLA-DAHQRTVRNVAWSPCGTRLASASFDATTCVWSRRDGDFEVTATLEGHENEVKGVAWAPSGNLLATCSRDKSVWIWEVDE--EEDYECASVLNSHTQDVKHVVWHPN-SEVLASASYDN---SIRLYREDGDDWSSFATLEGHESTVWSIDFDATGRRLVSCGDDKTIRIWQEGAATSSGGCICVAVGATWECVCTLSGHHTRVIYDVSW---------CKLTGAIATASGDDTIRVFEEEAVPEGDGKSPRFYE 295          

Query:   97 SIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFP--EKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWR 636
            S+   PSG   A S GGDK   + +W         +E D    + +  D  H + V  V WSP G  LAS S DA   +W ++        D  F  +      L GH  ++  +AW+P G  L + S D  + IW VD+    E  ++LN H   +K V W P    LAS S D+++R++R
Sbjct:   20 SVAWSPSGALIA-SCGGDK--TVRVWG--------REGDGWVCRSVLAD-AHQRTVRNVAWSPCGTRLASASFDATTCVWSRR--------DGDFEVTA----TLEGHENEVKGVAWAPSGNLLATCSRDKSVWIWEVDEEEDYECASVLNSHTQDVKHVVWHPNSEVLASASYDNSIRLYR 177          

Query:  250 HLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAI---LNGHNSFIKGVCWDPVGRYLASQSEDHTLRIW 633
            H+  VN VR+ PNG Y+A+GS D  V +W  ++ +              +A    GH   ++ LA+SP G  L SG  D R+ +W++       AI   L GH+  I  + + P G  LAS S D ++R+W
Sbjct:  426 HVSDVNVVRFHPNGSYVATGSADRTVRLWSAQQGS--------------AARLFTGHRGAVLALAFSPGGRLLASGGEDQRVRLWDIG----SGAIVKELRGHSDDITCLSFSPDGSALASGSSDGSVRVW 538          

Query:   94 CSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKI-------------------LYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDK-FPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKETKEEFLLLALGSKDRSLSVW 942
            C+ ++ P G     +G  D    + +W++ P + +    + +  +I                   + T   H   V  VR+ P G  L S S DA V  W  +   +             + +Q  GH+Y + D+  S  G Y CSGS D    +W  ++ FP +  +  GH S +  V + P G Y+A+ S D T+R+     W  +      +      +   L +SP G  ++A+G  +      +L++  + +   ++ GH   I C  + P          +   LA GS D S+ VW
Sbjct:  274 CAAEVAP-GMGMLAAGYEDSR--VMLWSLGPRKLRTARHNVDVARINLACDILDDKVVEDSKGSDVKTLRAHSGPVYAVRFLPGGAGLLSCSEDASVRFWDPRTFTNT------------AVYQ--GHAYPVWDVDVSALGLYFCSGSHDRTARLWVPERAFPLR--VYAGHVSDVNVVRFHPNGSYVATGSADRTVRL-----WSAQQGSAARLFTGHRGAVLALAFSP-GGRLLASGGEDQ---RVRLWDIGSGAIVKELRGHSDDITCLSFSP----------DGSALASGSSDGSVRVW 538          

Query:  181 DPIRNKEKETDENCPKILYTDYTHLKCVNCV-RWSPNGKYLASGSVDAVVVIWV--QKKLNDLEH-------------IDKKFHESYRSA--FQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKETKEEFLLLALGSKDRSLSVWTTLRRRPLVVISDLFTYS--IVDLSWYVEKFELMACSLDGSI 1062
            D IR + +E   N   +    +  +    C    +P    LA+G  D+ V++W    +KL    H             +D K  E  + +    LR HS  +  + + P G  L S S D  +  W+   F   TA+  GH   +  V    +G Y  S S D T R+     W  E      +          + + P+GS  VATG+++    T +L++    S      GH+  ++   + P             LLA G +D+ + +W         ++ +L  +S  I  LS+  +   L + S DGS+
Sbjct:  246 DSIR-RVREGPLNAATVCLYGFKSVPAPPCAAEVAPGMGMLAAGYEDSRVMLWSLGPRKLRTARHNVDVARINLACDILDDKVVEDSKGSDVKTLRAHSGPVYAVRFLPGGAGLLSCSEDASVRFWDPRTF-TNTAVYQGHAYPVWDVDVSALGLYFCSGSHDRTARL-----WVPERAFPLRVYAGHVSDVNVVRFHPNGS-YVATGSADR---TVRLWSAQQGSAARLFTGHRGAVLALAFSPG----------GRLLASGGEDQRVRLWDI---GSGAIVKELRGHSDDITCLSFSPDGSALASGSSDGSV 535          

Query:   91 ICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSN 759
            I S+D +P+ K+ A+   G     + +WN  P                Y    H   V  V++SP+G  + S S D  V +WV     +              +   + H+  +  +++S  G  L + S D  I +W V +  +    LN H+++++   + P GR + S S+D T+R+W ++     ++ C            ++ + P G+ I A GT N
Sbjct:   21 ITSVDFNPNMKQLAS---GSMDACLMVWNFKPQTRA------------YRFVGHKDAVMSVQFSPSGHLVVSASRDKTVRLWVPSVKGE--------------STVFKAHTATVRSVSFSADGQSLVTASDDKSIKVWTVHR-QKFLYSLNQHSNWVRSAKFSPDGRLIVSGSDDRTVRVWDSN-----SRECVHTFYEHGGFVNQVDFHPSGTCIAAAGTDN 208          

Query:  250 HLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVA 744
            H   +  V ++PN K LASGS+DA +++W              F    R A++  GH   ++ + +SP G  + S S D  + +W V     ++ +   H + ++ V +   G+ L + S+D ++++W         K    ++++S+   +   +SPDG  IV+
Sbjct:   17 HRDTITSVDFNPNMKQLASGSMDACLMVW-------------NFKPQTR-AYRFVGHKDAVMSVQFSPSGHLVVSASRDKTVRLW-VPSVKGESTVFKAHTATVRSVSFSADGQSLVTASDDKSIKVWTV----HRQKFLYSLNQHSNW-VRSAKFSPDGRLIVS 161          

Query:  406 QLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAI-LNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKETKEEFLLLALGSKDRSLSVWTTLRR 957
              +GH   I  + ++P+   L SGS+D  +++WN    P+  A    GH   +  V + P G  + S S D T+R+W  S   + T     + K  + + + +++S DG ++V                 D+ S  V  V  ++ +         +RS +   +  L+  GS DR++ VW +  R
Sbjct:   13 HFKGHRDTITSVDFNPNMKQLASGSMDACLMVWNFK--PQTRAYRFVGHKDAVMSVQFSPSGHLVVSASRDKTVRLWVPSVKGEST-----VFKAHTATVRSVSFSADGQSLVTAS--------------DDKSIKVWTVHRQKFLYSLNQHSNWVRSAKFSPDGRLIVSGSDDRTVRVWDSNSR 176          

Query:  211 DENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTS 642
            D N  + ++T Y H   VN V + P+G  +A+   D  V +W  +    L+H            +Q+ G + +   L++ P G YL + S D+ + + ++ +       L+GH      V +   G + AS   D  + +W+T+
Sbjct:  172 DSNSRECVHTFYEHGGFVNQVDFHPSGTCIAAAGTDNTVKVWDIRMNKLLQH------------YQVHGAAVN--SLSFHPTGNYLITASNDSTLKVLDLVE-GRLFYTLHGHQGPATAVAFSRAGDFFASGGSDEQVMVWKTN 300          

Query:   85 TEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSP-HGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIW 633
             ++  +D HP+ K    SG  D    I  W            D      L T + H   V  V+W+ NG +L + S D +  ++  + L +   I              RGH  +   +AW P H  +  SG  D  ++ W+V    E       H   I  + W P+G  L S S DHT + W
Sbjct:  245 ADVKCVDWHPT-KGLLVSGSKDSQQPIKFW------------DPKSGHSLATLHAHKNTVMEVKWNQNGNWLLTASRDHLCKLFDIRNLKEEVQI-------------FRGHKKEATAVAWHPIHEGFFASGGSDGSLLFWHVGVEKEVGGTDVAHEGMIWSLAWHPLGHILCSGSNDHTSKFW 402          

Query:  247 THLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNR--IIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDM------VGHKQHIICARYFPTLLRSKETKEEFLLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIV 1002
             H + +    ++P     A+ S D  V +W   + ++ E I             LRGH  D+  + W P    L SGS D++  I  W+  K     A L+ H + +  V W+  G +L + S DH  +++   + K+E ++     K ++     + W P      A+G S+       L+    W  GV+       V H+  I    + P             +L  GS D +   WT  R RP   + D +  +++
Sbjct:  200 AHKEPIREASFAPTDNKFATCSDDGTVRVWDFMRCHE-ERI-------------LRGHGADVKCVDWHPTKGLLVSGSKDSQQPIKFWDP-KSGHSLATLHAHKNTVMEVKWNQNGNWLLTASRDHLCKLFDIRNLKEEVQIFRGHKKEATA----VAWHPIHEGFFASGGSDG----SLLF----WHVGVEKEVGGTDVAHEGMIWSLAWHPL----------GHILCSGSNDHTSKFWT--RNRPGDKMRDRYNLNLL 420          

Query:   85 TEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSP-HGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIW 633
             ++  +D HP+ K    SG  D    I  W            D      L T + H   V  V+W+ NG +L + S D +  ++  + L +   I              RGH  +   +AW P H  +  SG  D  ++ W+V    E       H   I  + W P+G  L S S DHT + W
Sbjct:  245 ADVKCVDWHPT-KGLLVSGSKDSQQPIKFW------------DPKSGHSLATLHAHKNTVMEVKWNQNGNWLLTASRDHLCKLFDIRNLKEEVQI-------------FRGHKKEATAVAWHPIHEGFFASGGSDGSLLFWHVGVEKEVGGTDVAHEGMIWSLAWHPLGHILCSGSNDHTSKFW 402          

Query:  247 THLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNR--IIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDM------VGHKQHIICARYFPTLLRSKETKEEFLLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIV 1002
             H + +    ++P     A+ S D  V +W   + ++ E I             LRGH  D+  + W P    L SGS D++  I  W+  K     A L+ H + +  V W+  G +L + S DH  +++   + K+E ++     K ++     + W P      A+G S+       L+    W  GV+       V H+  I    + P             +L  GS D +   WT  R RP   + D +  +++
Sbjct:  200 AHKEPIREASFAPTDNKFATCSDDGTVRVWDFMRCHE-ERI-------------LRGHGADVKCVDWHPTKGLLVSGSKDSQQPIKFWDP-KSGHSLATLHAHKNTVMEVKWNQNGNWLLTASRDHLCKLFDIRNLKEEVQIFRGHKKEATA----VAWHPIHEGFFASGGSDG----SLLF----WHVGVEKEVGGTDVAHEGMIWSLAWHPL----------GHILCSGSNDHTSKFWT--RNRPGDKMRDRYNLNLL 420          

Query:   25 MRIVKPIYINYQNPQKDQILTEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKI---------LYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLR--GHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWR---TSDWKQETK-LCDEIDKNSSCS--FQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLL-------RSKETKEEFLLL------------------ALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELGIPLTLDE-MKQFFEKTYG 1146
            M++VK  ++ ++   +     EI ++D+   GK+ AT GG D  G I IW++D I  +  E +   P+I         L +   H   + CV++SP+GKYLASGS D +++IW   +    +      HE      + R   H  DI D+ W+P  + L +  +D  +I+WN   F EK    + H S +KGV +DP  +Y A+ S+D T++I+R   T D     + +  E  K S  +  F+R +WSPDG +I     +N    +  + NR  W   V ++GH      AR+ P L        + K+   E  L+                  A   +D+SL+VW+T R RP++V  D+   SI D+SW  +   L   SLD SI   +F ++ELG P+ L++ M+Q +   YG
Sbjct:    1 MKVVKFPWLAHREESRKY---EIYTVDVSHDGKRLAT-GGLD--GKIRIWSIDSIL-RCMELESLTPEIPLPQDLQMPLCSMSRHTGSITCVKFSPDGKYLASGSDDRILLIWALDEEQSSQPAFGSEHEREHWTVRKRLVAHDNDIQDICWAPDSSILVTVGLDRSVIVWNGSTF-EKLKRFDVHQSLVKGVVFDPANKYFATTSDDRTMKIFRYHKTGDISFTIEHIITEPFKESPLTTYFRRPSWSPDGQHIAVPNATNGPVSSVAIVNRGTWDTNVSLIGHDAPTEVARFNPRLFERNAGVKQKKDDDPENALVGQNDDKVHHFDKNIDSVVATAGQDKSLAVWSTSRPRPILVAFDIANKSITDMSWNPDGSLLFVASLDSSITLFKFENNELGKPIPLEKNMEQLYR--YG 407          

Query:  247 THLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEK---TAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSD 645
             H K +  V W P+   LA+GS D+ V IW ++     E  D+ F     +  +  GH  ++  +AWS  G YL + S D  + IW  D+  E+    ++L  H+  +K V W P    LAS S D T+RIW+  D
Sbjct:   56 AHKKAIRSVAWRPHTSLLAAGSFDSTVSIWAKE-----ESADRTFEMDLLAIIE--GHENEVKGVAWSNDGYYLATCSRDKSVWIWETDESGEEYECISVLQEHSQDVKHVIWHPSEALLASSSYDDTVRIWKDYD 184          

Query:  298 LASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKT------AILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKETKEEFLLLALGSKDRSLSVWTTL 951
            LA+GS D  + + V  K +D   ID               H   I  +AW PH + L +GS D+ + IW  ++  ++T      AI+ GH + +KGV W   G YLA+ S D ++ IW T +  +E + C  + +  S   + + W P    ++A+ + ++     + Y+ D+W     + GH+  +  + +  T        E    L  GS D ++ VW  +
Sbjct:   27 LATGSTDRKIKL-VSVKYDDFTLID---------VLDETAHKKAIRSVAWRPHTSLLAAGSFDSTVSIWAKEESADRTFEMDLLAIIEGHENEVKGVAWSNDGYYLATCSRDKSVWIWETDESGEEYE-CISVLQEHSQDVKHVIWHP-SEALLASSSYDDTVRIWKDYD-DDWECVAVLNGHEGTVWSSDFDKT--------EGVFRLCSGSDDSTVRVWKYM 229          

Query:  163 ISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIW-NVDKFPEKTAILNGHNSFIKGVCWDPV-GRY-LASQSEDHTLRIWR 636
            +SIW  +   ++  E D     +L     H   V  V WS +G YLA+ S D  V IW   +            E Y     L+ HS D+  + W P    L S S D+ + IW + D   E  A+LNGH   +    +D   G + L S S+D T+R+W+
Sbjct:   82 VSIWAKEESADRTFEMD-----LLAIIEGHENEVKGVAWSNDGYYLATCSRDKSVWIWETDESG----------EEYECISVLQEHSQDVKHVIWHPSEALLASSSYDDTVRIWKDYDDDWECVAVLNGHEGTVWSSDFDKTEGVFRLCSGSDDSTVRVWK 227          

Query:   73 DQILTEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKETKEEFLLLALGSKDRSLSVW 942
            D  + +I +ID HP       S   D            I+N +   +E   ++L     H + ++ V++ P+GK++ S S D    +W           D   H+         GH   +  L++   G+ +CSG +D+  ++W++ +   K   L GH+  I  V W P G  +A+   D  + +W     + E +L   +   +  +  R +    G  +V+ G  N       +Y+ D W K   + GH   II          S +       L  G  DRS+ +W
Sbjct:  215 DSHVGKIGAIDWHPDSNNQMISCAEDGL----------IKNFQYSNEEGGLRLLGDLVGHERRISDVKYHPSGKFIGSASHDMTWRLW-----------DASTHQEL---LLQEGHDKGVFSLSFQCDGSLVCSGGMDSLSMLWDI-RSGSKVMTLAGHSKPIYTVAWSPNGYQVATGGGDGIINVWDIRK-RDEGQLNQILAHRNIVTQVRFSKEDGGKKLVSCGYDN----LINVYSSDTWLKMGSLAGHTDKII----------SLDISNNSHFLVSGGWDRSIKLW 464          

Query:  124 KFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYT-----HLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLN-DLEHIDKKFHESYRSAF------------QLRGHS-----YDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNG---HNSFIKGVCWDPVGRYLASQSEDHTLRIW---------------RTSDWKQETKLCDEI--------DKNSSCSFQRLTWSPDGSNIVATG-----TSNNGAPTCQLYNRD---NWSKGVD------MVGHKQHIICARYFP----TLLRSKETKEEFLLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQF-TDDELGI----------PLTLDEMKQFFEKTYGSGFVVDNSAISKSKNNA 1197
            K  T+GG +K   + IW ++     E   +    KI   D+      H + +N +R++  G  LAS   D  V++W Q+  N   E + + F     ++             +LRG S      +I DLAWSP    +    +DN I +++V        ++ G   H  +++GV WDP+ +++ SQS D +L ++               R+   K E     ++        ++     F+R + SP G  +V          +  A    +Y R    N + GV       +   K+  + A + P    T  +S       L+ A+ + +  L V+ T    PL V+ ++    I DL+W  +   L+  S DG  +YV   T+ + G           PL  DE     +    +G +V+   + K   N+
Sbjct:   29 KLFTAGGDNK---VRIWKLN---RDENGQNGGVRKIESLDFLGSLTHHEQAINVIRFNSKGDVLASAGDDGQVLLWKQEDPNTQQESVVRPFGMDAETSEADENKEKWVVWKRLRGGSGATAAAEIYDLAWSPDNRNIVVACMDNSIRLFDVGA----GMLVCGQSDHGHYVQGVAWDPLNQFILSQSADRSLHVYGVILSSAGVVTGLKLRSKIAKAELPCPGDVLRTNYLFHNETLPSFFRRCSISPCGGLVVIPSGVYKVAGDEVANCVYVYTRSGILNSAGGVKNRPAIRIPSLKKPALMAAFSPVFYETCQKSVLKLPYKLVFAIATTNEVL-VYDTDVLEPLCVVGNIHYSPITDLAWSEDGSTLLISSTDGFCSYVSIDTETQFGSRIEPPAMHAEPLDTDESAVAAKNQREAGGIVNMLPVKKIPCNS 453          

Query:  262 VNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPV----GRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSC--SFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKG---------VDMVGHKQHIICARYFPTLLRSKETKEEFLLLALGSKDRSLSVWTTLRRRPLVVI 975
            +  V +SP+GK+LA+G+ D ++ IW      D+E+         +    L+GH  DI  L + P G  L SGS D  + IW++     +T   +   S   GV    V    G+Y+A+ S D  +R+W +       +L  E +  +    S   + ++ DG ++V +G+ +       L N +N S           V  +GHK  ++          +    +E++L   GSKDR +  W      PL+++
Sbjct:  446 IRSVCFSPDGKFLATGAEDRLIRIW------DIEN--------RKIVMILQGHEQDIYSLDYFPSGDKLVSGSGDRTVRIWDL-----RTGQCSLTLSIEDGVTTVAVSPGDGKYIAAGSLDRAVRVWDSETGFLVERLDSENESGTGHKDSVYSVVFTRDGQSVV-SGSLDRSVKLWNLQNANNKSDSKTPNSGTCEVTYIGHKDFVLSV--------ATTQNDEYIL--SGSKDRGVLFWDKKSGNPLLML 668          

Query:   25 MRIVKPIYINYQNPQKDQILTEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIW-VQKKLNDLEHID-----KKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDE-IDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKETKE-----EFLLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELGIPLTLDEMKQFFEKTYGSGFVVDNSAISKS--KNNAFIIPESSAVLKXXXXXXXXNHDRKSTSLHLLNEKKTGPNEQII-----CHTKTGKRRITPKFLSSLDDEDIEPDP 1407
            MR++KP ++++           I SIDIHP G +FA  G GD+ G +SIWNM PI+N+E E +EN PK+L     HL CVNCVRWS NGKYLASG  D +++IW + + L  +   +     K   E +R    LR HS D++DLAWSP  ++L SGSVDN + IWN  KFPE   I+ GH   +KGV WDPVG+YLASQS+D TLR+WRT+DW+QET + +  ++ + +    RL+WSPDG  +V+    NN  P  ++  RD W   +D VGH++ I C R+ P L   K   +     ++   A+G +DRSLS+W T  +RPLVV+ DLF +SI+D+SW    FEL+ CS DGSIAY  FT +ELG  ++ +E  +F ++ YG       S  + S  +N   +  +   ++K Q        D  S+   ++          I+       TK G+RRITP  ++ +D  D  P P
Sbjct:    1 MRLLKPNWVSHDG-------KPIFSIDIHPDGSRFAVGGQGDECGKVSIWNMAPIKNEEDEMNENVPKLLCQMDNHLACVNCVRWSGNGKYLASGGDDNLIMIWQMARYLGAMPTFESGGGGKLNIEQWRCVHTLRQHSGDVLDLAWSPDDSFLASGSVDNTVTIWNAQKFPEVIQIIKGHTGLVKGVTWDPVGKYLASQSDDKTLRVWRTTDWQQETSVTEPFLECSGTTHVLRLSWSPDGHYVVSAHAMNNSGPVAKILERDGWKTKMDFVGHRKAITCVRFNPKLFVKKVNGDSTRLKQYSCCAIGCRDRSLSIWLTSLKRPLVVVHDLFNHSIMDVSWSQSGFELLVCSWDGSIAYANFTSEELGKAMSQEEKDKFHKQVYGISISSSRSKFTSSIIENPEMLKIQQRHIMKQQTLASTNKPDSNSSPCKMVRPSSLSLGLNILEQQRETRTKDGRRRITPVLVAQMDVNDT-PQP 472          

Query: 2209 WEITQTKQISVMAHFKDKLFVGDVCGFLHSFYLKGGRIQAPFSLDSGLTSLVCDGRYLIAVTVRATLYIWSIAPFAIFLK-ESFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSN----KSEFWSVSKLSSKNLINKPLASMQSSESIC---DGPMKNLSSIVKQELILDRLEIQVKLAESLHSCEEYKYWLLLWVRHLIEADKEVRVRDICQRFLGPIHTST----KSNWDPFILRYSKRELLKEILPLFALNLRLQRLYT 3018
            WE   T     +A  ++ + V      L  F   G R+Q P  L+S  + L   G +++ VT    +Y+W     ++ +K ES    L   G    I   SIS  G   LT  + +S+ F   +  W ++    +     +++ +            PLA +Q   +      G M   +   +Q   +  LE Q+ +  +L S +EY +WLL +VR+L +A  E R+R+IC+  LGP H S     ++ W+P +L + +R+LL EILP+   N+RLQRL+T
Sbjct:  711 WEAMITSPGIALAGSRNIVCVACANKSLCVFSFSGRRLQPPLMLESCASVLQASGHHVLVVTSSGGVYVWDTKSSSVVVKNESLCSFLA--GSDVTIARTSISERGYPVLTLSNQASYSFEPCVGAWIQLVRAEDPLLLNADYQASMFRQDPFCARGPLAQLQGHSTRLARQGGRMFRSNPSKQQTATMSHLENQLSVCLTLGSADEYHFWLLTYVRYLAQAGCESRLREICEDLLGPPHRSNVSDKRTGWNPKVLSFKRRDLLVEILPIIGTNIRLQRLFT 990          

Query:  205 ETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHI---DKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSS-------------------------CSFQRLTWSPDGSN-IVATG---TSNNGAPTCQLYNRDNWSKGVDMV-GHKQHIICARYFPTLLRSKETKEE----------------FLLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELGIP 1101
            E   N  K L     H K VN VR+SP  + LAS   D+VV IW     ++ +HI   +    E++  +  LRGH  D+ DLAWSP GT L SGSVDN  IIW+  K   K  IL  H  +++GVCWDP+G+Y+ + S D + R++ +  +    + C  I+K S+                           F+R T++PDG++ IV  G     N    T  +++R++ SK V  +   K+  +  R  P +   +++KE                  ++ A+ + D  L ++ T ++ P   +S++    I D++W      L+  S DG  + + F D ELG P
Sbjct:   48 ENGSNNLKFLSNLTRHTKAVNVVRFSPKEELLASAGDDSVVFIWKLTCSSEHQHILDDENDNLETWTVSKMLRGHIEDVYDLAWSPDGTQLLSGSVDNSAIIWDAIK-GTKLTILKDHKHYVQGVCWDPLGQYVVTNSSDRSCRLYNSLSY----RCCYNINKLSANVMSKNTEKGEAIKPTRMFHDEAMLTFFRRPTFTPDGTHFIVPAGKLELQNQVVHTTYIFSRNSPSKPVCFLQSPKKPTVAVRCCPAVFELRDSKESDKENSGRNSSLSKLPYRMVFAVATLDAVL-LYDTQQQVPFAYVSNIHYSGISDMAWSNNGSTLVISSTDGYCSMLYFKDGELGTP 389          

Query:   25 MRIVKPIYINYQNPQKDQILTEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIW 336
            MR++KP ++++           I SIDIHP G +FA  G GD+ G +SIWNM PI+N+E E +EN PK+L     HL CVNCVRWS NGKYLASG  D +++IW
Sbjct:    1 MRLLKPNWVSHDG-------KPIFSIDIHPDGSRFAVGGQGDECGKVSIWNMAPIKNEEDEMNENVPKLLCQMDNHLACVNCVRWSGNGKYLASGGDDNLIMIW 97          

Query:  250 HLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVG-----RYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLT---WSPDG 729
            H + V  V +SP+G+YLASGS D  V  W      +  H            F  +GH + I+ +AWSP G  L SG  +  I IW+     +    L GH  +I  + W+P+      RYLAS S+D +++IW T+           +DK  S   Q +T   W  +G
Sbjct:   98 HTEAVISVAFSPDGRYLASGSGDTTVRFW--DVTTETPH------------FTCKGHMHWILHIAWSPDGKKLASGCKNGEIRIWDPATGKQMGKTLKGHLKWITWLSWEPLHRNPDCRYLASSSKDSSVKIWDTA--------TGSVDKTFSSHTQSVTCVKWGGEG 243          

Query:  394 RSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNV-DKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETK-LCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKETKEEFLLLALGSKDRSLSVW 942
            R    + GH+  ++ +A+SP G YL SGS D  +  W+V  + P  T    GH  +I  + W P G+ LAS  ++  +RIW  +  KQ  K L   +   +  S++ L  +PD   +     S++   + ++++    S       H Q + C ++            E L+ +  S+DR++ VW
Sbjct:   90 RCTSSIPGHTEAVISVAFSPDGRYLASGSGDTTVRFWDVTTETPHFTC--KGHMHWILHIAWSPDGKKLASGCKNGEIRIWDPATGKQMGKTLKGHLKWITWLSWEPLHRNPDCRYLA----SSSKDSSVKIWDTATGSVDKTFSSHTQSVTCVKW----------GGEGLIYS-ASQDRTIKVW 257          

Query:  250 HLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRI 630
            H   +N V +SP+G+ +AS + D  V +W                E+ +    LRGH   +  +AWS     +CSGS D+ + +W++ K  +    L GH   +  V W P G  + S  +D  L++
Sbjct:  353 HQALINQVCFSPDGRLIASAAFDKSVKLWNG--------------ETGKFITSLRGHVNCVYQIAWSADCRLICSGSADSTLKVWDM-KTKKLLYDLPGHADEVYSVDWSPDGARVGSGGKDKVLKM 464          

Query:  247 THLKCVNCVRWSPNGKYLASGSVDAVVVIW----------VQKKLNDLEHI---------DKKFHESYRSAFQ------LRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLR 873
            +H + V CV+W   G  + S S D  + +W          +Q   + + H+            F  S  +  Q      L+  +      A       L SGS D  + +W  +   +  A + GH + I  VC+ P GR +AS + D ++++W     K  T L   ++    C +Q + WS D   ++ +G++++   T ++++        D+ GH   +    + P   R
Sbjct:  229 SHTQSVTCVKWGGEG-LIYSASQDRTIKVWRAEDGVLCRTLQGHAHWVNHMALNTDYVLRTGAFEPSKGTTLQTMSAETLQSEASKRYKEAKGSKAERLVSGSDDFTLFLWEPEAKTKPIARMTGHQALINQVCFSPDGRLIASAAFDKSVKLWNGETGKFITSLRGHVN----CVYQ-IAWSAD-CRLICSGSADS---TLKVWDMKTKKLLYDLPGHADEVYSVDWSPDGAR 452          

Query:   91 ICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAW-----SPHGTYLCSGSVDNRIIIWN-----VDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSD 645
            + S+   P G+  A SG GD    +  W++        ET        +T   H+  +  + WSP+GK LASG  +  + IW       +                L+GH   I  L+W     +P   YL S S D+ + IW+     VDK        + H   +  V W   G  + S S+D T+++WR  D
Sbjct:  102 VISVAFSPDGRYLA-SGSGDT--TVRFWDV------TTETPH------FTCKGHMHWILHIAWSPDGKKLASGCKNGEIRIWDPATGKQMGKT-------------LKGHLKWITWLSWEPLHRNPDCRYLASSSKDSSVKIWDTATGSVDK------TFSSHTQSVTCVKWGGEG-LIYSASQDRTIKVWRAED 261          

Query:  211 DENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWR 636
            D    K+L+T   H   + CV +S +GK  AS + D +V++W                 + +  F L+GH++ +    +SP+G +LCSGS DN  IIW++ K    T +LN H + I+   +    + +A+ S D T+R+W 
Sbjct:   27 DSKTGKVLFTLEHHDGAIKCVCFSSDGKLFASAAYDHLVMVWEAA--------------TGKQVFCLQGHTHSVETCCFSPNGAFLCSGSWDNTAIIWSL-KNGMPTYVLNKHRNVIQTCAFSHDSKTVATGSWDCTVRLWH 153          

Query:  226 KILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQ-----------------------------LRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTS 642
            K ++    H   V    +SPNG +L SGS D   +IW  K       ++K  +     AF                              L GH  ++  LA++ +   L SGS D  I +W+  K  E   +L GH+ +++   +   G  LAS S+D T+R+W TS
Sbjct:   74 KQVFCLQGHTHSVETCCFSPNGAFLCSGSWDNTAIIWSLKNGMPTYVLNKHRNVIQTCAFSHDSKTVATGSWDCTVRLWHLVEGDMAVKCLDGHKSNVHSLAFAKN-HMLASGSWDMTIRLWD-SKTGELIHLLTGHSGWVQACSFSGSGDLLASASDDQTVRVWDTS 239          

Query:   25 MRIVKPIYINYQNPQKDQILTEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHI---DKKFH--ESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDK-NSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKE-------TKEEFLLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELGIPLTLDEMKQFFEKTYGSGFVVDNSAISKSKNNAFIIPESSAVLKXXXXXXXXNHDRKST---SLHLLNEKKTGPN-------------------EQIICHTKTGKRRITPKFLSSLDDEDIEPDPAPSKRIY-SPETIPEILVPNKSKEDENVLISNAVKVSSKFKSVLEEKFVKPDSPNIVSSS-EDRRDSLNSLKIKTQRKDDKANDNKSSCGIDSKSPKKDEKSVDSISTKIGSSVEKSPKKDDKVFEMPTAL 1794
            M+++KP ++++           I S+DIHP G KFAT G G+  G + IWNM P+  +E E ++N PK+L     HL CVNCVRWS NG YLASG  D +V++W +  L     +     K    E +R    LR H+ D++D+AWSPH  +L S SVDN I+IWN  KFPE    L GH   +KG+ WDPVG+Y+ASQ++DH+L++WRT DW+ +  +     +   +    RL+WSPDG  +V+    NN  PT Q+  RD W   +D VGH++ +   ++ P + + K+           +   A+GSKDRSLSVW T  +RPLVVI DLF  SI+D+SW +    ++ CS+DG++AY+ F+ DELG PL  +E     +  YG    + N     S      I E+  +LK          +R++T   S+     + + P                    +Q+   T  G+RRITP  ++ LD  D  P    S  I  S  +I   L P  + +      S+  ++ S  +   +     P  PN  +   ED +DS+ +  + T      A+  +    +DS+  ++  K+   ++  I S+   +P   D+  E P AL
Sbjct:    1 MKLLKPSWVSHNG-------KPIFSVDIHPDGTKFATGGQGEDSGKVMIWNMAPVLREEDEKNDNIPKMLCQMDNHLACVNCVRWSNNGLYLASGGDDKLVMVWKRAALIGPSTVFGSSTKLANVEQWRCVTILRNHTGDVMDVAWSPHDVWLASCSVDNTIVIWNARKFPEMVTCLRGHTGLVKGLTWDPVGKYIASQADDHSLKVWRTVDWQMDANITKPFTECGGTTHVLRLSWSPDGQYLVSAHAMNNSGPTAQIVERDGWKTNMDFVGHRKAVTVVKFNPKIFKKKQKNGSSPKPSAPYCCCAVGSKDRSLSVWLTSLKRPLVVIHDLFDKSIMDISWTLTGLGMLVCSMDGTVAYLDFSLDELGDPLNEEEKNTIHQNIYGKSLAITNMEAQLSTT----IIENPEMLKY-------QQERQTTTQASMAAAGPESSAPKVNSVMNGESLEDIRKNLLKKQVETRTADGRRRITPLCIAQLDTGDFSPALFNSVPILPSGSSISNQLAPQLNSD------SSPGQMPSGLRPGQDPVLTSP--PNSATRGLEDHKDSMKATLLLTS-----ASKIEPMKALDSRFTER-SKATPGVTAAIASTAGLAPL--DRPKETPAAL 593          

Query: 2197 DQKLWEITQTKQISVMAHFKDKLFVGDVCGFLHSFYLKGGRIQAPFSLDSGLTSLVCDGRYLIAVTVRATLYIWSIAPF-AIFLKESFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSNK----SEFWSVSKLSSKNLINKPLASMQSSESICDGPMKNLSSI---VKQELILDRLEIQVKLAESLHSCEEYKYWLLLWVRHLIEADKEVRVRDICQRFLGPIHTSTKSNWDPFILRYSKRELLKEILPLFALNLRLQRLYT 3018
            D + W       +   A   D L V  V   L  F   G R+     L + +++L C   +++ +T  ATL +W +    A+   ES   +L+  G  T +    ++ +G   +   +G S+ F+  +  W  V +  +     ++F S          + PLA MQ            LSS    ++Q + +  LE Q+  A  L S +EY+YWLL++ R L+    E R+R++C+  LGP+H S  S+W+P  L   KRELL+E+LP+   NLR QRL+T
Sbjct:  730 DGRDWSTLLPSSVMAAAGSSDVLAVVCVDRMLSVFSACGRRLLPSIQLATPVSALHCSAHFVMVLTAGATLSVWDVHKHKAVVKNESLQSILS--GADTTVSQSLLTPQGVPVVGLSNGKSYCFSCALESWTLVADKGDSLVQCADFRSCMASHDAPASSGPLAVMQGRNLSAGRLASRLSSTPHHLQQSMTMAFLENQLASALMLQSAQEYRYWLLIYARFLVNEGSEFRLRELCKELLGPVHKSAASSWEPTTLGLQKRELLREVLPVIGENLRFQRLFT 1009          

Query:  250 HLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKK--FHE---------SYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQ----------------ETKLCDEIDKNSSCS-FQRLTWSPDGSNIVATG----TSNNGAPTCQLYNRDNWSKGVDMVGHKQHII-----CARYFPTLLRSKETKEEF-------------LLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELGIPL 1104
            H K VN VR+SPNG  LASG  DA +++W   KLND +  ++   F E         S+     LRGH  D+ D+ W+ +G ++ SGSVDN  I+W+V K  +K  ILN H S+++GV WDP+G+Y+A+ S D  LR++ T   K+                E K       +S  S F+RL+++PDGS ++          N   T  +++R +  + V  +            C  YF   LR+K+ ++               ++ A+ S+D S+ ++ T +  P  ++S++  +++ DLSW  +   L   S DG  +++ F+  ELG PL
Sbjct:   65 HTKAVNVVRFSPNGDLLASGGDDAAILLW---KLNDTKEPEQAPVFQEDEDALLNKESWSVVKTLRGHIEDVYDVCWTRNGNFMVSGSVDNTAIMWDVSKG-QKLCILNDHKSYVQGVTWDPLGQYVATLSCDRVLRVYSTHTKKKAVTVSKMSSGQPAEGGEAKQYRMFQDDSMRSFFRRLSFTPDGSFLITPAGCVEVGENIINTTYIFSRKSLKRPVAHLPCPSKATLAVRCCPVYF--ELRTKKGEDGSIQDLPNLFKLPYRMVFAVASED-SIFLYDTQQSLPFGLVSNIHYHTLSDLSWSADGSFLAVSSTDGYCSFLSFSPGELGTPL 392          

Query:  250 HLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKK--FHE---------SYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQ----------------ETKLCDEIDKNSSCS-FQRLTWSPDGSNIVATG----TSNNGAPTCQLYNRDNWSKGVDMVGHKQHII-----CARYFPTLLRSKETKEEF-------------LLLALGSKDRSLSVWTTLRRRPLVVISDLFTYSIVDLSWYVEKFELMACSLDGSIAYVQFTDDELGIPL 1104
            H K VN VR+SPNG  LASG  DA +++W   KLND +  ++   F E         S+     LRGH  D+ D+ W+ +G ++ SGSVDN  I+W+V K  +K  ILN H S+++GV WDP+G+Y+A+ S D  LR++ T   K+                E K       +S  S F+RL+++PDGS ++          N   T  +++R +  + V  +            C  YF   LR+K+ ++               ++ A+ S+D S+ ++ T +  P  ++S++  +++ DLSW  +   L   S DG  +++ F+  ELG PL
Sbjct:   65 HTKAVNVVRFSPNGDLLASGGDDAAILLW---KLNDTKEPEQAPVFQEDEDALLNKESWSVVKTLRGHIEDVYDVCWTRNGNFMVSGSVDNTAIMWDVSKG-QKLCILNDHKSYVQGVTWDPLGQYVATLSCDRVLRVYSTHTKKKAVTVSKMSSGQPAEGGEAKQYRMFQDDSMRSFFRRLSFTPDGSFLITPAGCVEVGENIINTTYIFSRKSLKRPVAHLPCPSKATLAVRCCPVYF--ELRTKKGEDGSIQDLPNLFKLPYRMVFAVASED-SIFLYDTQQSLPFGLVSNIHYHTLSDLSWSADGSFLAVSSTDGYCSFLSFSPGELGTPL 392          

Query:  250 HLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVG-----RYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDG 729
            H + V    +SP GKYLASGS D  V  W           D      + +A   RGH++ ++ +AWSP G  L SG  +++I +W+     +    L GH  +I  +CW+P+      RYLAS S+D ++RIW T+        CD+I    + S   + W  DG
Sbjct:  106 HTEAVISTAFSPTGKYLASGSGDTTVRFW-----------DLSTETPHHTA---RGHTHWVLSIAWSPDGKKLASGCKNSQICLWDPVTGAQIGKTLTGHTKWITWLCWEPLHLNPECRYLASTSKDGSVRIWDTA-----LGRCDKILTGHTQSVTCVKWGGDG 251          

Query:  250 HLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWR 636
            H   VN V +SP+ + LAS S D  V IW  +    L                LRGH   +  +AWS     L SGS D+ + +W+V K  + +  L GH   +  V W P G+ +AS  +D  LRIWR
Sbjct:  364 HSALVNEVLFSPDTRLLASASFDKSVKIWDGRTGKYL--------------MSLRGHVGSVYQVAWSADSRLLVSGSSDSTLKVWDV-KTGKLSIDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIWR 477          

Query:   82 LTEIC--SIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFH----ESYRSAFQLRGHSYDIVDLAWSPHGTY------------------------LCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKETKEEFLLLALGSKDRSLSVW 942
            +T +C   + ++P  +  A++    K G + IW+    R         C KIL     H + V CV+W  +G  L + S D  V +W  K       +    H     +  + + LR  +++      +P                            L SGS D  + +WN     +  A + GH++ +  V + P  R LAS S D +++IW     K    L   +      S  ++ WS D S ++ +G+S++   T ++++       +D+ GH   +    + P   R          +A G KD+ L +W
Sbjct:  195 ITWLCWEPLHLNPECRYLAST---SKDGSVRIWDTALGR---------CDKILTG---HTQSVTCVKWGGDG-LLYTSSHDRTVKVWRAKDGVQCRTLQGHAHWVNTLALSTDYVLRTGAFEPATATINPQDVTGALEEVKERALQRYNKVRGSNPERLVSGSDDFTLFLWNPAADKKPLARMTGHSALVNEVLFSPDTRLLASASFDKSVKIWDGRTGKYLMSLRGHVG-----SVYQVAWSAD-SRLLVSGSSDS---TLKVWDVKTGKLSIDLPGHADEVYAVDWSPDGQR----------VASGGKDKCLRIW 476          

Query:   91 ICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAW-----SPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSD 645
            + S    P+GK  A SG GD    +  W++        ET        +T   H   V  + WSP+GK LASG  ++ + +W       +                L GH+  I  L W     +P   YL S S D  + IW+         IL GH   +  V W   G  L + S D T+++WR  D
Sbjct:  110 VISTAFSPTGKYLA-SGSGDT--TVRFWDL------STETPH------HTARGHTHWVLSIAWSPDGKKLASGCKNSQICLWDPVTGAQIGKT-------------LTGHTKWITWLCWEPLHLNPECRYLASTSKDGSVRIWDT-ALGRCDKILTGHTQSVTCVKWGGDG-LLYTSSHDRTVKVWRAKD 269          

Query:  250 HLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVG-----RYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDG 729
            H + V    +SP GKYLASGS D  V  W           D      + +A   RGH++ ++ +AWSP G  L SG  +++I +W+     +    L GH  +I  +CW+P+      RYLAS S+D ++RIW T+        CD+I    + S   + W  DG
Sbjct:  105 HTEAVISTAFSPTGKYLASGSGDTTVRFW-----------DLSTETPHHTA---RGHTHWVLSIAWSPDGKKLASGCKNSQICLWDPVTGAQIGKTLTGHTKWITWLCWEPLHLNPECRYLASTSKDGSVRIWDTA-----LGRCDKILTGHTQSVTCVKWGGDG 250          

Query:  250 HLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWR 636
            H   VN V +SP+ + LAS S D  V IW  +    L                LRGH   +  +AWS     L SGS D+ + +W+V K  + +  L GH   +  V W P G+ +AS  +D  LRIWR
Sbjct:  349 HSALVNEVLFSPDTRLLASASFDKSVKIWDGRTGKYL--------------MSLRGHVGSVYQVAWSADSRLLVSGSSDSTLKVWDV-KTGKLSIDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIWR 462          

Query:   82 LTEIC--SIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFH----ESYRSAFQLRGHSYD-------IVDLAWSPHGT---YLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYFPTLLRSKETKEEFLLLALGSKDRSLSVW 942
            +T +C   + ++P  +  A++    K G + IW+    R         C KIL     H + V CV+W  +G  L + S D  V +W  K       +    H     +  + + LR  +++       +    + P G+    L SGS D  + +WN     +  A + GH++ +  V + P  R LAS S D +++IW     K    L   +      S  ++ WS D S ++ +G+S++   T ++++       +D+ GH   +    + P   R          +A G KD+ L +W
Sbjct:  194 ITWLCWEPLHLNPECRYLAST---SKDGSVRIWDTALGR---------CDKILTG---HTQSVTCVKWGGDG-LLYTSSHDRTVKVWRAKDGVQCRTLQGHAHWVNTLALSTDYVLRTGAFEPSPARTPLQHSGFVPQGSNPERLVSGSDDFTLFLWNPAADKKPLARMTGHSALVNEVLFSPDTRLLASASFDKSVKIWDGRTGKYLMSLRGHVG-----SVYQVAWSAD-SRLLVSGSSDS---TLKVWDVKTGKLSIDLPGHADEVYAVDWSPDGQR----------VASGGKDKCLRIW 461          

Query:   91 ICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAW-----SPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSD 645
            + S    P+GK  A SG GD    +  W++        ET        +T   H   V  + WSP+GK LASG  ++ + +W       +                L GH+  I  L W     +P   YL S S D  + IW+         IL GH   +  V W   G  L + S D T+++WR  D
Sbjct:  109 VISTAFSPTGKYLA-SGSGDT--TVRFWDL------STETPH------HTARGHTHWVLSIAWSPDGKKLASGCKNSQICLWDPVTGAQIGKT-------------LTGHTKWITWLCWEPLHLNPECRYLASTSKDGSVRIWDT-ALGRCDKILTGHTQSVTCVKWGGDG-LLYTSSHDRTVKVWRAKD 268          

Query: 1510 VSSKFKSVLEEKFVKPDSPNIVSSSEDRRDSLNSLKIKTQRKDDKANDNKSSCGIDSKSPKKDEKSVDSISTKIGSSVEKSPKKDDKVFEMPTALVTKPKLLKDLESVPSNNDLKSTVNSRRSILYKDVVEKLNSEAVKPXXXXXXXXXXXXXXXESPKKIFRES------------------------------------------KSVTEKRLFLSQSVLKHNYSLLCLLPGDHDHFVVKIISENGTGSKTPTSNQADPKVYKICVNNNDQKLWEITQTKQISVMAHFKDKLFVGDVCGFLHSFYLKGGRIQAPFSLDSGLTSLVCDGRYLIAVTVRATLYIWSIAPFAIFLKESFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSNKSEFWSVSKLSSKNLINKPLASMQSSESICDGPMKNLSSIVKQELILDRLEIQVKLAESLHSCEEYKYWLLLWVRHLIEA 2850
            VSSKFKSVLEEKFVKPDSPNIVSSSEDRRDSLNSLK KTQRKDDKANDNKSSCGIDSKSPKKDEKS+DSISTK GSSVEKSPKKDDKVFEMPTALVTKPKLLKDLESVPSNNDLKSTVNSRRSILYKDVVEKLNSEAVKPLDISTVSSISLSTVDESPKKIFRES                                          KSVTEKRLFLSQSVLKHNYSLLCLLPGDHDHFVVKIISENGTGSKTPTSNQADPKVYKICVNNNDQKLWEITQTKQISVMAHFKDKLFVGDVCGFLHSFYLKGGRIQAPFSLDSGLTSLVCDGRYLIAVTVRATLYIWSIAPFAIFLKESFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSNKSEFWSVSKLSSKNLINKPLASMQSSESICDGPMKNLSSIVKQELILDRLEIQVKLAESLHSCEEYKYWLLLWVRHLIEA
Sbjct:  209 VSSKFKSVLEEKFVKPDSPNIVSSSEDRRDSLNSLKNKTQRKDDKANDNKSSCGIDSKSPKKDEKSIDSISTKSGSSVEKSPKKDDKVFEMPTALVTKPKLLKDLESVPSNNDLKSTVNSRRSILYKDVVEKLNSEAVKPLDISTVSSISLSTVDESPKKIFRESNSEDEPYGVAYCIHFGDEDAENEDEEDEDASKYRINRLLKLAKSVTEKRLFLSQSVLKHNYSLLCLLPGDHDHFVVKIISENGTGSKTPTSNQADPKVYKICVNNNDQKLWEITQTKQISVMAHFKDKLFVGDVCGFLHSFYLKGGRIQAPFSLDSGLTSLVCDGRYLIAVTVRATLYIWSIAPFAIFLKESFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSNKSEFWSVSKLSSKNLINKPLASMQSSESICDGPMKNLSSIVKQELILDRLEIQVKLAESLHSCEEYKYWLLLWVRHLIEA 697          

Query:   25 MRIVKPIYINYQNPQKDQILTEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICARYF-----PTLLRSKETKEEFL 900
            MRIVKPIYINYQNPQKDQILTEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHL  V+ + WSP+G YL SGSVD  ++IW         ++D KF E  ++A  L GH+  I  + W P G YL S S D+ + IW                                           RTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMV  K   +    F     P ++ S E + + L
Sbjct:    1 MRIVKPIYINYQNPQKDQILTEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLNIVD-LAWSPHGTYLCSGSVDNRIIIW---------NVD-KFPE--KTAI-LNGHNSFIKGVCWDPVGRYLASQSEDHTLRIW-------------------------------------------RTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVSSKFKSVLEEKFVKPDSPNIVSSSEDRRDSL 240          

Query: 1510 VSSKFKSVLEEKFVKPDSPNIVSSSEDRRDSLNSLKIKTQRKDDKANDNKSSCGIDSKSPKKDEKSVDSISTKIGSSVEKSPKKDDKVFEMPTALVTKPKLLKDLESVPSNNDLKSTVNSRRSILYKDVVEKLNSEAVKPXXXXXXXXXXXXXXXESPKKIFRES------------------------------------------KSVTEKRLFLSQSVLKHNYSLLCLLPGDHDHFVVKIISENGTGSKTPTSNQADPKVYKICVNNNDQKLWEITQTKQISVMAHFKDKLFVGDVCGFLHSFYLKGGRIQAPFSLDSGLTSLVCDGRYLIAVTVRATLYIWSIAPFAIFLKESFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSNKSEFWSVSKLSSKNLINKPLASMQSSESICDGPMKNLSSIVKQELILDRLEIQVKLAESLHSCEEYKYWLLLWVRHLIEA 2850
            VSSKFKSVLEEKFVKPDSPNIVSSSEDRRDSLNSLK KTQRKDDKANDNKSSCGIDSKSPKKDEKS+DSISTK GSSVEKSPKKDDKVFEMPTALVTKPKLLKDLESVPSNNDLKSTVNSRRSILYKDVVEKLNSEAVKPLDISTVSSISLSTVDESPKKIFRES                                          KSVTEKRLFLSQSVLKHNYSLLCLLPGDHDHFVVKIISENGTGSKTPTSNQADPKVYKICVNNNDQKLWEITQTKQISVMAHFKDKLFVGDVCGFLHSFYLKGGRIQAPFSLDSGLTSLVCDGRYLIAVTVRATLYIWSIAPFAIFLKESFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSNKSEFWSVSKLSSKNLINKPLASMQSSESICDGPMKNLSSIVKQELILDRLEIQVKLAESLHSCEEYKYWLLLWVRHLIEA
Sbjct:  219 VSSKFKSVLEEKFVKPDSPNIVSSSEDRRDSLNSLKNKTQRKDDKANDNKSSCGIDSKSPKKDEKSIDSISTKSGSSVEKSPKKDDKVFEMPTALVTKPKLLKDLESVPSNNDLKSTVNSRRSILYKDVVEKLNSEAVKPLDISTVSSISLSTVDESPKKIFRESNSEDEPYGVAYCIHFGDEDAENEDEEDEDASKYRINRLLKLAKSVTEKRLFLSQSVLKHNYSLLCLLPGDHDHFVVKIISENGTGSKTPTSNQADPKVYKICVNNNDQKLWEITQTKQISVMAHFKDKLFVGDVCGFLHSFYLKGGRIQAPFSLDSGLTSLVCDGRYLIAVTVRATLYIWSIAPFAIFLKESFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSNKSEFWSVSKLSSKNLINKPLASMQSSESICDGPMKNLSSIVKQELILDRLEIQVKLAESLHSCEEYKYWLLLWVRHLIEA 707          

Query:   25 MRIVKPIYINYQNPQKDQILTEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICA--RYFPTLLRSKETKEEFLLLALGSKDR 927
            MRIVKPIYINYQNPQKDQILTEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHL  V+ + WSP+G YL SGSVD  ++IW         ++D KF E  ++A  L GH+  I  + W P G YL S S D+ + IW                                           RTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICA    F ++L  K  K +   +   S+DR
Sbjct:    1 MRIVKPIYINYQNPQKDQILTEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLNIVD-LAWSPHGTYLCSGSVDNRIIIW---------NVD-KFPE--KTAI-LNGHNSFIKGVCWDPVGRYLASQSEDHTLRIW-------------------------------------------RTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICAVSSKFKSVLEEKFVKPDSPNIVSSSEDR 246          

Query: 1510 VSSKFKSVLEEKFVKPDSPNIVSSSEDRRDSLNSLKIKTQRKDDKANDNKSSCGIDSKSPKKDEKSVDSISTKIGSSVEKSPKKDDKVFEMPTALVTKPKLLKDLESVPSNNDLKSTVNSRRSILYKDVVEKLNSEAVKPXXXXXXXXXXXXXXXESPKKIFRES------------------------------------------KSVTEKRLFLSQSVLKHNYSLLCLLPGDHDHFVVKIISENGTGSKTPTSNQADPKVYKICVNNNDQKLWEITQTKQISVMAHFKDKLFVGDVCGFLHSFYLKGGRIQAPFSLDSGLTSLVCDGRYLIAVTVRATLYIWSIAPFAIFLKESFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSNKSEFWSVSKLSSKNLINKPLASMQSSESICDGPMKNLSSIVKQELILDRLEIQVKLAESLHSCEEYKYWLLLWVRHLIEA 2850
            VSSKFKSVLEEKFVKPDSPNIVSSSEDRRDSLNSLK KTQRKDDKANDNKSSCGIDSKSPKKDEKS+DSISTK GSSVEKSPKKDDKVFEMPTALVTKPKLLKDLESVPSNNDLKSTVNSRRSILYKDVVEKLNSEAVKPLDISTVSSISLSTVDESPKKIFRES                                          KSVTEKRLFLSQSVLKHNYSLLCLLPGDHDHFVVKIISENGTGSKTPTSNQADPKVYKICVNNNDQKLWEITQTKQISVMAHFKDKLFVGDVCGFLHSFYLKGGRIQAPFSLDSGLTSLVCDGRYLIAVTVRATLYIWSIAPFAIFLKESFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSNKSEFWSVSKLSSKNLINKPLASMQSSESICDGPMKNLSSIVKQELILDRLEIQVKLAESLHSCEEYKYWLLLWVRHLIEA
Sbjct:  160 VSSKFKSVLEEKFVKPDSPNIVSSSEDRRDSLNSLKNKTQRKDDKANDNKSSCGIDSKSPKKDEKSIDSISTKSGSSVEKSPKKDDKVFEMPTALVTKPKLLKDLESVPSNNDLKSTVNSRRSILYKDVVEKLNSEAVKPLDISTVSSISLSTVDESPKKIFRESNSEDEPYGVAYCIHFGDEDAENEDEEDEDASKYRINRLLKLAKSVTEKRLFLSQSVLKHNYSLLCLLPGDHDHFVVKIISENGTGSKTPTSNQADPKVYKICVNNNDQKLWEITQTKQISVMAHFKDKLFVGDVCGFLHSFYLKGGRIQAPFSLDSGLTSLVCDGRYLIAVTVRATLYIWSIAPFAIFLKESFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSNKSEFWSVSKLSSKNLINKPLASMQSSESICDGPMKNLSSIVKQELILDRLEIQVKLAESLHSCEEYKYWLLLWVRHLIEA 648          

Query:  427 DIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICA--RYFPTLLRSKETKEEFLLLALGSKDR 927
            DIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICA    F ++L  K  K +   +   S+DR
Sbjct:   19 DIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICAVSSKFKSVLEEKFVKPDSPNIVSSSEDR 187          

Query: 1510 VSSKFKSVLEEKFVKPDSPNIVSSSEDRRDSLNSLKIKTQRKDDKANDNKSSCGIDSKSPKKDEKSVDSISTKIGSSVEKSPKKDDKVFEMPTALVTKPKLLKDLESVPSNNDLKSTVNSRRSILYKDVVEKLNSEAVKPXXXXXXXXXXXXXXXESPKKIFRES------------------------------------------KSVTEKRLFLSQSVLKHNYSLLCLLPGDHDHFVVKIISENGTGSKTPTSNQADPKVYKICVNNNDQKLWEITQTKQISVMAHFKDKLFVGDVCGFLHSFYLKGGRIQAPFSLDSGLTSLVCDGRYLIAVTVRATLYIWSIAPFAIFLKESFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSNKSEFWSVSKLSSKNLINKPLASMQSSESICDGPMKNLSSIVKQELILDRLEIQVKLAESLHSCEEYKYWLLLWVRHLIEA 2850
            VSSKFKSVLEEKFVKPDSPNIVSSSEDRRDSLNSLK KTQRKDDKANDNKSSCGIDSKSPKKDEKS+DSISTK GSSVEKSPKKDDKVFE+PTALVTKPKLLKDLESVPSNNDLKSTVNSRRSILYKDVVEKLNSEAVKPLDISTVSSISLSTVDESPKKIFRES                                          KSVTEKRLFLSQSVLKHNYSLLCLLPGDHDHFVVKIISENGTGSKTPTSNQADPKVYKICVNNNDQKLWEITQTKQISVMAHFKDKLFVGDVCGFLHSFYLKGGRIQAPFSLDSGLTSLVCDGRYLIAVTVRATLYIWSIAPFAIFLKESFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSNKSEFWSVSKLSSKNLINKPLASMQSSESICDGPMKNLSSIVKQELILDRLEIQVKLAESLHSCEEYKYWLLLWVRHLIEA
Sbjct:  219 VSSKFKSVLEEKFVKPDSPNIVSSSEDRRDSLNSLKNKTQRKDDKANDNKSSCGIDSKSPKKDEKSIDSISTKSGSSVEKSPKKDDKVFEIPTALVTKPKLLKDLESVPSNNDLKSTVNSRRSILYKDVVEKLNSEAVKPLDISTVSSISLSTVDESPKKIFRESNSEDEPYGVAYCIHFGDEDAENEDEEDEDASKYRINRLLKLAKSVTEKRLFLSQSVLKHNYSLLCLLPGDHDHFVVKIISENGTGSKTPTSNQADPKVYKICVNNNDQKLWEITQTKQISVMAHFKDKLFVGDVCGFLHSFYLKGGRIQAPFSLDSGLTSLVCDGRYLIAVTVRATLYIWSIAPFAIFLKESFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSNKSEFWSVSKLSSKNLINKPLASMQSSESICDGPMKNLSSIVKQELILDRLEIQVKLAESLHSCEEYKYWLLLWVRHLIEA 707          

Query:   25 MRIVKPIYINYQNPQKDQILTEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLKCVNCVRWSPNGKYLASGSVDAVVVIWVQKKLNDLEHIDKKFHESYRSAFQLRGHSYDIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICA--RYFPTLLRSKETKEEFLLLALGSKDR 927
            MRIVKPIYINYQNPQKDQILTEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHL  V+ + WSP+G YL SGSVD  ++IW         ++D KF E  ++A  L GH+  I  + W P G YL S S D+ + IW                                           RTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICA    F ++L  K  K +   +   S+DR
Sbjct:    1 MRIVKPIYINYQNPQKDQILTEICSIDIHPSGKKFATSGGGDKYGIISIWNMDPIRNKEKETDENCPKILYTDYTHLNIVD-LAWSPHGTYLCSGSVDNRIIIW---------NVD-KFPE--KTAI-LNGHNSFIKGVCWDPVGRYLASQSEDHTLRIW-------------------------------------------RTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICAVSSKFKSVLEEKFVKPDSPNIVSSSEDR 246          

Query: 1987 KIFRESKSVTEKRLFLSQSVLKHNYSLLCLLPGDHDHFVVKIISENGTGSKTPTSNQADPKVYKICVNNNDQKLWEITQTKQISVMAHFKDKLFVGDVCGFLHSFYLKGGRIQAPFSLDSGLTSLVCDGRYLIAVTVRATLYIWSIAPFAIFLKESFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSNKSEFWSVSKLSSKNLINKPLASMQSSESICDGPMKNLSSIVKQELILDRLEIQVKLAESLHSCEEYKYWLLLWVRHLIEA 2850
            ++ + +KSVTEKRLFLSQSVLKHNYSLLCLLPGDHDHFVVKIISENGTGSKTPTSNQADPKVYKICVNNNDQKLWEITQTKQISVMAHFKDKLFVGDVCGFLHSFYLKGGRIQAPFSLDSGLTSLVCDGRYLIAVTVRATLYIWSIAPFAIFLKESFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSNKSEFWSVSKLSSKNLINKPLASMQSSESICDGPMKNLSSIVKQELILDRLEIQVKLAESLHSCEEYKYWLLLWVRHLIEA
Sbjct:  444 RLLKLAKSVTEKRLFLSQSVLKHNYSLLCLLPGDHDHFVVKIISENGTGSKTPTSNQADPKVYKICVNNNDQKLWEITQTKQISVMAHFKDKLFVGDVCGFLHSFYLKGGRIQAPFSLDSGLTSLVCDGRYLIAVTVRATLYIWSIAPFAIFLKESFVHLLTDDGDKTGIKNISISTEGNISLTFDSGSSFYFNKPIAVWQEVFNNSNKSEFWSVSKLSSKNLINKPLASMQSSESICDGPMKNLSSIVKQELILDRLEIQVKLAESLHSCEEYKYWLLLWVRHLIEA 731          

Query:  427 DIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICA--RYFPTLLRSKETKEEFLLLALGSKDR 927
            DIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICA    F ++L  K  K +   +   S+DR
Sbjct:   19 DIVDLAWSPHGTYLCSGSVDNRIIIWNVDKFPEKTAILNGHNSFIKGVCWDPVGRYLASQSEDHTLRIWRTSDWKQETKLCDEIDKNSSCSFQRLTWSPDGSNIVATGTSNNGAPTCQLYNRDNWSKGVDMVGHKQHIICAVSSKFKSVLEEKFVKPDSPNIVSSSEDR 187          

Query: 1510 VSSKFKSVLEEKFVKPDSPNIVSSSEDRRDSLNSLKIKTQRKDDKANDNKSSCGIDSKSPKKDEKSVDSISTKIGSSVEKSPKKDDKVFEMPTALVTKPKLLKDLESVPSNNDLKSTVNSRRSILYKDVVEKLNSEAVKPXXXXXXXXXXXXXXXESPKKIFRES 2004
            VSSKFKSVLEEKFVKPDSPNIVSSSEDRRDSLNSLK KTQRKDDKANDNKSSCGIDSKSPKKDEKS+DSISTK GSSVEKSPKKDDKVFEMPTALVTKPKLLKDLESVPSNNDLKSTVNSRRSILYKDVVEKLNSEAVKPLDISTVSSISLSTVDESPKKIFRES
Sbjct:  160 VSSKFKSVLEEKFVKPDSPNIVSSSEDRRDSLNSLKNKTQRKDDKANDNKSSCGIDSKSPKKDEKSIDSISTKSGSSVEKSPKKDDKVFEMPTALVTKPKLLKDLESVPSNNDLKSTVNSRRSILYKDVVEKLNSEAVKPLDISTVSSISLSTVDESPKKIFRES 324