Potassium voltage-gated channel subfamily A member 2
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30020664 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 3
Homology
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Human
Match: KCNA2 (potassium voltage-gated channel subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:6220]) HSP 1 Score: 336.65 bits (862), Expect = 3.218e-108 Identity = 162/385 (42.08%), Postives = 249/385 (64.68%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIP-----------------KYSKMCID-NKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXX-----FKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RV IN+SGL FET + L + P TLLG P R ++FD RNEYFFDR+R +F+ I +YY+ G +++RP NVP D+F E+ +++L + F D+GY+ E+ + LP N +++W+LFEYPE+SG A + IVS+++ ++SI +FC+ET+P YS I ++ +F FFI ET+C IWF+ E + R +CP+ + + N++DIVA+IPY+ITL L ++ D ++G ++++ + + + FKL++HS GLQ+L T +AS+ LG+ + + + ++LFSS +Y+ E D ++S SIPDAFWW V++M TVGYGDMVP ++ G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 33 ERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTEL-AEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 416
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Human
Match: KCNA2 (potassium voltage-gated channel subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:6220]) HSP 1 Score: 336.65 bits (862), Expect = 3.218e-108 Identity = 162/385 (42.08%), Postives = 249/385 (64.68%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIP-----------------KYSKMCID-NKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXX-----FKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RV IN+SGL FET + L + P TLLG P R ++FD RNEYFFDR+R +F+ I +YY+ G +++RP NVP D+F E+ +++L + F D+GY+ E+ + LP N +++W+LFEYPE+SG A + IVS+++ ++SI +FC+ET+P YS I ++ +F FFI ET+C IWF+ E + R +CP+ + + N++DIVA+IPY+ITL L ++ D ++G ++++ + + + FKL++HS GLQ+L T +AS+ LG+ + + + ++LFSS +Y+ E D ++S SIPDAFWW V++M TVGYGDMVP ++ G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 33 ERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTEL-AEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 416
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Human
Match: KCNA2 (potassium voltage-gated channel subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:6220]) HSP 1 Score: 336.65 bits (862), Expect = 3.218e-108 Identity = 162/385 (42.08%), Postives = 249/385 (64.68%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIP-----------------KYSKMCID-NKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXX-----FKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RV IN+SGL FET + L + P TLLG P R ++FD RNEYFFDR+R +F+ I +YY+ G +++RP NVP D+F E+ +++L + F D+GY+ E+ + LP N +++W+LFEYPE+SG A + IVS+++ ++SI +FC+ET+P YS I ++ +F FFI ET+C IWF+ E + R +CP+ + + N++DIVA+IPY+ITL L ++ D ++G ++++ + + + FKL++HS GLQ+L T +AS+ LG+ + + + ++LFSS +Y+ E D ++S SIPDAFWW V++M TVGYGDMVP ++ G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 33 ERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTEL-AEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 416
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Human
Match: KCNA2 (potassium voltage-gated channel subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:6220]) HSP 1 Score: 336.65 bits (862), Expect = 3.218e-108 Identity = 162/385 (42.08%), Postives = 249/385 (64.68%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIP-----------------KYSKMCID-NKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXX-----FKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RV IN+SGL FET + L + P TLLG P R ++FD RNEYFFDR+R +F+ I +YY+ G +++RP NVP D+F E+ +++L + F D+GY+ E+ + LP N +++W+LFEYPE+SG A + IVS+++ ++SI +FC+ET+P YS I ++ +F FFI ET+C IWF+ E + R +CP+ + + N++DIVA+IPY+ITL L ++ D ++G ++++ + + + FKL++HS GLQ+L T +AS+ LG+ + + + ++LFSS +Y+ E D ++S SIPDAFWW V++M TVGYGDMVP ++ G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 33 ERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTEL-AEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 416
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Human
Match: KCNA2 (potassium voltage-gated channel subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:6220]) HSP 1 Score: 336.65 bits (862), Expect = 3.218e-108 Identity = 162/385 (42.08%), Postives = 249/385 (64.68%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIP-----------------KYSKMCID-NKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXX-----FKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RV IN+SGL FET + L + P TLLG P R ++FD RNEYFFDR+R +F+ I +YY+ G +++RP NVP D+F E+ +++L + F D+GY+ E+ + LP N +++W+LFEYPE+SG A + IVS+++ ++SI +FC+ET+P YS I ++ +F FFI ET+C IWF+ E + R +CP+ + + N++DIVA+IPY+ITL L ++ D ++G ++++ + + + FKL++HS GLQ+L T +AS+ LG+ + + + ++LFSS +Y+ E D ++S SIPDAFWW V++M TVGYGDMVP ++ G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 33 ERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTEL-AEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 416
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Celegans
Match: shk-1 (Potassium voltage-gated channel protein shk-1 [Source:UniProtKB/Swiss-Prot;Acc:Q8I4B0]) HSP 1 Score: 270.396 bits (690), Expect = 6.843e-84 Identity = 148/387 (38.24%), Postives = 226/387 (58.40%), Query Frame = 1 Query: 469 SVAEGH--SKSRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEK-IKLPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPK----------YSKMCIDNKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXXF-----KLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 S +GH + V INVSG+ F+T+ S L R+P +LLG R+ F S NE+FFDRHR FE I + Y+ G ++KRP VP D+FL EM +F++ +++ F +GY K + +P+N +KIW L EYP++S A + +S+ + +SI +FC ET+P + +D + S FF E +C +WFTIE+I R +SCP + N++D VA+ P+++ N F+D K SS++ + L + KL++HS GLQ+L TF++S+ + + M ++++LF+S +Y+ E +S SIP +FW+ ++TM TVGYGD+VP S G++VG CA+ GVLTLA+ VPII NF F Sbjct: 34 SSTQGHPYTDQIVTINVSGMRFQTFESTLSRYPNSLLGDRNKRQHFFVSDTNEFFFDRHRTTFESILYIYQSGGRVKRPEIVPIDIFLKEMRFFQMGDDLLEEFWIAEGYEKPKEVMMPNNKTQRKIWELMEYPDSSLSARIIAFISIAVIALSIISFCWETVPSDIEEKPINNSATAELLDEMDEKHYSPFFWIELMCILWFTIELILRFISCPCKVTFATSVLNIIDFVAIAPFFV---NFFFADTS----KSNSSMSFAVLRVLRLVRVFRVFKLSRHSVGLQILGKTFRSSVQEFCLLIFFMAIALVLFASGMYFAEQGEPNSKFTSIPASFWFVLVTMTTVGYGDLVPLSPFGKVVGGMCAMIGVLTLALPVPIIVANFKHF 413
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Celegans
Match: shk-1 (Potassium voltage-gated channel protein shk-1 [Source:UniProtKB/Swiss-Prot;Acc:Q8I4B0]) HSP 1 Score: 270.396 bits (690), Expect = 6.843e-84 Identity = 148/387 (38.24%), Postives = 226/387 (58.40%), Query Frame = 1 Query: 469 SVAEGH--SKSRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEK-IKLPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPK----------YSKMCIDNKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXXF-----KLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 S +GH + V INVSG+ F+T+ S L R+P +LLG R+ F S NE+FFDRHR FE I + Y+ G ++KRP VP D+FL EM +F++ +++ F +GY K + +P+N +KIW L EYP++S A + +S+ + +SI +FC ET+P + +D + S FF E +C +WFTIE+I R +SCP + N++D VA+ P+++ N F+D K SS++ + L + KL++HS GLQ+L TF++S+ + + M ++++LF+S +Y+ E +S SIP +FW+ ++TM TVGYGD+VP S G++VG CA+ GVLTLA+ VPII NF F Sbjct: 34 SSTQGHPYTDQIVTINVSGMRFQTFESTLSRYPNSLLGDRNKRQHFFVSDTNEFFFDRHRTTFESILYIYQSGGRVKRPEIVPIDIFLKEMRFFQMGDDLLEEFWIAEGYEKPKEVMMPNNKTQRKIWELMEYPDSSLSARIIAFISIAVIALSIISFCWETVPSDIEEKPINNSATAELLDEMDEKHYSPFFWIELMCILWFTIELILRFISCPCKVTFATSVLNIIDFVAIAPFFV---NFFFADTS----KSNSSMSFAVLRVLRLVRVFRVFKLSRHSVGLQILGKTFRSSVQEFCLLIFFMAIALVLFASGMYFAEQGEPNSKFTSIPASFWFVLVTMTTVGYGDLVPLSPFGKVVGGMCAMIGVLTLALPVPIIVANFKHF 413
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Celegans
Match: shk-1 (Potassium voltage-gated channel protein shk-1 [Source:UniProtKB/Swiss-Prot;Acc:Q8I4B0]) HSP 1 Score: 270.396 bits (690), Expect = 1.012e-83 Identity = 148/387 (38.24%), Postives = 226/387 (58.40%), Query Frame = 1 Query: 469 SVAEGH--SKSRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEK-IKLPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPK----------YSKMCIDNKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXXF-----KLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 S +GH + V INVSG+ F+T+ S L R+P +LLG R+ F S NE+FFDRHR FE I + Y+ G ++KRP VP D+FL EM +F++ +++ F +GY K + +P+N +KIW L EYP++S A + +S+ + +SI +FC ET+P + +D + S FF E +C +WFTIE+I R +SCP + N++D VA+ P+++ N F+D K SS++ + L + KL++HS GLQ+L TF++S+ + + M ++++LF+S +Y+ E +S SIP +FW+ ++TM TVGYGD+VP S G++VG CA+ GVLTLA+ VPII NF F Sbjct: 47 SSTQGHPYTDQIVTINVSGMRFQTFESTLSRYPNSLLGDRNKRQHFFVSDTNEFFFDRHRTTFESILYIYQSGGRVKRPEIVPIDIFLKEMRFFQMGDDLLEEFWIAEGYEKPKEVMMPNNKTQRKIWELMEYPDSSLSARIIAFISIAVIALSIISFCWETVPSDIEEKPINNSATAELLDEMDEKHYSPFFWIELMCILWFTIELILRFISCPCKVTFATSVLNIIDFVAIAPFFV---NFFFADTS----KSNSSMSFAVLRVLRLVRVFRVFKLSRHSVGLQILGKTFRSSVQEFCLLIFFMAIALVLFASGMYFAEQGEPNSKFTSIPASFWFVLVTMTTVGYGDLVPLSPFGKVVGGMCAMIGVLTLALPVPIIVANFKHF 426
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Celegans
Match: shk-1 (Potassium voltage-gated channel protein shk-1 [Source:UniProtKB/Swiss-Prot;Acc:Q8I4B0]) HSP 1 Score: 270.011 bits (689), Expect = 3.194e-83 Identity = 148/387 (38.24%), Postives = 226/387 (58.40%), Query Frame = 1 Query: 469 SVAEGH--SKSRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEK-IKLPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPK----------YSKMCIDNKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXXF-----KLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 S +GH + V INVSG+ F+T+ S L R+P +LLG R+ F S NE+FFDRHR FE I + Y+ G ++KRP VP D+FL EM +F++ +++ F +GY K + +P+N +KIW L EYP++S A + +S+ + +SI +FC ET+P + +D + S FF E +C +WFTIE+I R +SCP + N++D VA+ P+++ N F+D K SS++ + L + KL++HS GLQ+L TF++S+ + + M ++++LF+S +Y+ E +S SIP +FW+ ++TM TVGYGD+VP S G++VG CA+ GVLTLA+ VPII NF F Sbjct: 80 SSTQGHPYTDQIVTINVSGMRFQTFESTLSRYPNSLLGDRNKRQHFFVSDTNEFFFDRHRTTFESILYIYQSGGRVKRPEIVPIDIFLKEMRFFQMGDDLLEEFWIAEGYEKPKEVMMPNNKTQRKIWELMEYPDSSLSARIIAFISIAVIALSIISFCWETVPSDIEEKPINNSATAELLDEMDEKHYSPFFWIELMCILWFTIELILRFISCPCKVTFATSVLNIIDFVAIAPFFV---NFFFADTS----KSNSSMSFAVLRVLRLVRVFRVFKLSRHSVGLQILGKTFRSSVQEFCLLIFFMAIALVLFASGMYFAEQGEPNSKFTSIPASFWFVLVTMTTVGYGDLVPLSPFGKVVGGMCAMIGVLTLALPVPIIVANFKHF 459
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Celegans
Match: shk-1 (Potassium voltage-gated channel protein shk-1 [Source:UniProtKB/Swiss-Prot;Acc:Q8I4B0]) HSP 1 Score: 270.011 bits (689), Expect = 1.048e-82 Identity = 150/383 (39.16%), Postives = 230/383 (60.05%), Query Frame = 1 Query: 469 SVAEGH--SKSRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEK-IKLPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPK----------YSKMCIDNKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGG-SSXXXXXXXXXXXXFKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 S +GH + V INVSG+ F+T+ S L R+P +LLG R+ F S NE+FFDRHR FE I + Y+ G ++KRP VP D+FL EM +F++ +++ F +GY K + +P+N +KIW L EYP++S A + +S+ + +SI +FC ET+P + +D + S FF E +C +WFTIE+I R +SCP + N++D VA+ P+++ N F+D + L +LR++R+ R+FKL++HS GLQ+L TF++S+ + + M ++++LF+S +Y+ E +S SIP +FW+ ++TM TVGYGD+VP S G++VG CA+ GVLTLA+ VPII NF F Sbjct: 123 SSTQGHPYTDQIVTINVSGMRFQTFESTLSRYPNSLLGDRNKRQHFFVSDTNEFFFDRHRTTFESILYIYQSGGRVKRPEIVPIDIFLKEMRFFQMGDDLLEEFWIAEGYEKPKEVMMPNNKTQRKIWELMEYPDSSLSARIIAFISIAVIALSIISFCWETVPSDIEEKPINNSATAELLDEMDEKHYSPFFWIELMCILWFTIELILRFISCPCKVTFATSVLNIIDFVAIAPFFV---NFFFADTSKSNSSMSFAVLRVLRLVRVFRVFKLSRHSVGLQILGKTFRSSVQEFCLLIFFMAIALVLFASGMYFAEQGEPNSKFTSIPASFWFVLVTMTTVGYGDLVPLSPFGKVVGGMCAMIGVLTLALPVPIIVANFKHF 502
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Fly
Match: Sh (gene:FBgn0003380 transcript:FBtr0089660) HSP 1 Score: 330.872 bits (847), Expect = 2.650e-105 Identity = 163/388 (42.01%), Postives = 241/388 (62.11%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSKMCIDNKNYN-----------FLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLF-SDNCIDGKKGGSSXXXXXXXXXXXX--------------FKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RV INVSGL FET + L++ P TLLG P R ++FD RNEYFFDR R +F+ I +YY+ G +++RP NVP DVF E+++++L IN F D+G++ E+ + LP N +K+W+LFEYPE+S A V I+S+ + ++SI FC+ET+P++ + N N FF+ ET+C IWFT E+ R ++CPN + +D NV+DI+A+IPY+ITLA ++ ++ ++ K S + + + FKL++HS GLQ+L T +AS+ LG+ + + + ++LFSS +Y+ E ++S SIPDAFWW V+TM TVGYGDM P G+IVGS C ++GVLT+A+ VP+I NFN F Sbjct: 52 ERVVINVSGLRFETQLRTLNQFPDTLLGDPARRLRYFDPLRNEYFFDRSRPSFDAILYYYQSGGRLRRPVNVPLDVFSEEIKFYELGDQAINKFREDEGFIKEEERPLPDNEKQRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLPEFKHYKVFNTTTNGTKIEEDEVPDITDPFFLIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAIIPYFITLATVVAEEEDTLNLPKAPVSPQDKSSNQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGRTLKASMRELGLLIFFLFIGVVLFSSAVYFAEAGSENSFFKSIPDAFWWAVVTMTTVGYGDMTPVGFWGKIVGSLCVIAGVLTIALPVPVIVSNFNYF 439
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Fly
Match: Sh (gene:FBgn0003380 transcript:FBtr0089657) HSP 1 Score: 333.183 bits (853), Expect = 3.174e-105 Identity = 164/388 (42.27%), Postives = 243/388 (62.63%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSKMCIDNKNYN-----------FLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLF-SDNCIDGKKGGSSXXXXXXXXXXXX--------------FKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RV INVSGL FET + L++ P TLLG P R ++FD RNEYFFDR R +F+ I +YY+ G +++RP NVP DVF E+++++L IN F D+G++ E+ + LP N +K+W+LFEYPE+S A V I+S+ + ++SI FC+ET+P++ + N N FF+ ET+C IWFT E+ R ++CPN + +D NV+DI+A+IPY+ITLA ++ ++ ++ K S + + + FKL++HS GLQ+L T +AS+ LG+ + + + ++LFSS +Y+ E ++S SIPDAFWW V+TM TVGYGDM P + G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 97 ERVVINVSGLRFETQLRTLNQFPDTLLGDPARRLRYFDPLRNEYFFDRSRPSFDAILYYYQSGGRLRRPVNVPLDVFSEEIKFYELGDQAINKFREDEGFIKEEERPLPDNEKQRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLPEFKHYKVFNTTTNGTKIEEDEVPDITDPFFLIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAIIPYFITLATVVAEEEDTLNLPKAPVSPQDKSSNQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGRTLKASMRELGLLIFFLFIGVVLFSSAVYFAEAGSENSFFKSIPDAFWWAVVTMTTVGYGDMTPVGVWGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 484
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Fly
Match: Sh (gene:FBgn0003380 transcript:FBtr0302903) HSP 1 Score: 332.413 bits (851), Expect = 3.742e-105 Identity = 164/388 (42.27%), Postives = 243/388 (62.63%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSKMCIDNKNYN-----------FLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLF-SDNCIDGKKGGSSXXXXXXXXXXXX--------------FKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RV INVSGL FET + L++ P TLLG P R ++FD RNEYFFDR R +F+ I +YY+ G +++RP NVP DVF E+++++L IN F D+G++ E+ + LP N +K+W+LFEYPE+S A V I+S+ + ++SI FC+ET+P++ + N N FF+ ET+C IWFT E+ R ++CPN + +D NV+DI+A+IPY+ITLA ++ ++ ++ K S + + + FKL++HS GLQ+L T +AS+ LG+ + + + ++LFSS +Y+ E ++S SIPDAFWW V+TM TVGYGDM P + G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 85 ERVVINVSGLRFETQLRTLNQFPDTLLGDPARRLRYFDPLRNEYFFDRSRPSFDAILYYYQSGGRLRRPVNVPLDVFSEEIKFYELGDQAINKFREDEGFIKEEERPLPDNEKQRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLPEFKHYKVFNTTTNGTKIEEDEVPDITDPFFLIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAIIPYFITLATVVAEEEDTLNLPKAPVSPQDKSSNQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGRTLKASMRELGLLIFFLFIGVVLFSSAVYFAEAGSENSFFKSIPDAFWWAVVTMTTVGYGDMTPVGVWGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 472
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Fly
Match: Sh (gene:FBgn0003380 transcript:FBtr0089661) HSP 1 Score: 332.413 bits (851), Expect = 3.742e-105 Identity = 164/388 (42.27%), Postives = 243/388 (62.63%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSKMCIDNKNYN-----------FLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLF-SDNCIDGKKGGSSXXXXXXXXXXXX--------------FKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RV INVSGL FET + L++ P TLLG P R ++FD RNEYFFDR R +F+ I +YY+ G +++RP NVP DVF E+++++L IN F D+G++ E+ + LP N +K+W+LFEYPE+S A V I+S+ + ++SI FC+ET+P++ + N N FF+ ET+C IWFT E+ R ++CPN + +D NV+DI+A+IPY+ITLA ++ ++ ++ K S + + + FKL++HS GLQ+L T +AS+ LG+ + + + ++LFSS +Y+ E ++S SIPDAFWW V+TM TVGYGDM P + G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 85 ERVVINVSGLRFETQLRTLNQFPDTLLGDPARRLRYFDPLRNEYFFDRSRPSFDAILYYYQSGGRLRRPVNVPLDVFSEEIKFYELGDQAINKFREDEGFIKEEERPLPDNEKQRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLPEFKHYKVFNTTTNGTKIEEDEVPDITDPFFLIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAIIPYFITLATVVAEEEDTLNLPKAPVSPQDKSSNQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGRTLKASMRELGLLIFFLFIGVVLFSSAVYFAEAGSENSFFKSIPDAFWWAVVTMTTVGYGDMTPVGVWGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 472
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Fly
Match: Sh (gene:FBgn0003380 transcript:FBtr0302902) HSP 1 Score: 332.413 bits (851), Expect = 3.742e-105 Identity = 164/388 (42.27%), Postives = 243/388 (62.63%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSKMCIDNKNYN-----------FLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLF-SDNCIDGKKGGSSXXXXXXXXXXXX--------------FKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RV INVSGL FET + L++ P TLLG P R ++FD RNEYFFDR R +F+ I +YY+ G +++RP NVP DVF E+++++L IN F D+G++ E+ + LP N +K+W+LFEYPE+S A V I+S+ + ++SI FC+ET+P++ + N N FF+ ET+C IWFT E+ R ++CPN + +D NV+DI+A+IPY+ITLA ++ ++ ++ K S + + + FKL++HS GLQ+L T +AS+ LG+ + + + ++LFSS +Y+ E ++S SIPDAFWW V+TM TVGYGDM P + G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 85 ERVVINVSGLRFETQLRTLNQFPDTLLGDPARRLRYFDPLRNEYFFDRSRPSFDAILYYYQSGGRLRRPVNVPLDVFSEEIKFYELGDQAINKFREDEGFIKEEERPLPDNEKQRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLPEFKHYKVFNTTTNGTKIEEDEVPDITDPFFLIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAIIPYFITLATVVAEEEDTLNLPKAPVSPQDKSSNQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGRTLKASMRELGLLIFFLFIGVVLFSSAVYFAEAGSENSFFKSIPDAFWWAVVTMTTVGYGDMTPVGVWGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 472
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Zebrafish
Match: kcna2b (potassium voltage-gated channel, shaker-related subfamily, member 2b [Source:ZFIN;Acc:ZDB-GENE-080204-89]) HSP 1 Score: 338.576 bits (867), Expect = 3.641e-109 Identity = 163/381 (42.78%), Postives = 247/381 (64.83%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIKL-PSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSKMCID-NKNYN-------------FLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXX-----FKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RV IN+SGL FET + L + P TLLG P R ++FD RNEYFFDR+R +F+ I +YY+ G +++RP NV D+F E+ +++L I F D+G++ E+ KL P N +++W+LFEYPE+SG A + I+S+++ ++SI +FC+ET+P + D +K Y F FFI ET+C IWF+ E + R +CP+ + + N++DIVA+IPY+ITL L ++ DG++G ++++ + + + FKL++HS GLQ+L T +AS+ LG+ + + + ++LFSS +Y+ E D DS SIPDAFWW V++M TVGYGDMVP ++ G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 33 ERVVINISGLRFETQLKTLSQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVTLDIFSEEIRFYELGEEAIEMFREDEGFIKEEEKLLPENEFQRQVWLLFEYPESSGPARIIAIISVMVILISIVSFCLETLPVFRNEETDMHKAYRTDSNSTISYTSTYFTDPFFILETLCIIWFSFEFLVRFFACPSKAGFFVNIMNIIDIVAIIPYFITLGTEL-AEKAEDGQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADEPDSQFVSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 412
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Zebrafish
Match: kcna1a (potassium voltage-gated channel, shaker-related subfamily, member 1a [Source:ZFIN;Acc:ZDB-GENE-110408-15]) HSP 1 Score: 335.88 bits (860), Expect = 4.214e-108 Identity = 165/380 (43.42%), Postives = 247/380 (65.00%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSK------MCIDNKNYNF-----LSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXX-------FKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RV IN++GL FET + L + P TLLG+P R ++FD RNEYFFDR+R +F+ I +YY+ G +++RPANVP D+F E+++++L + F D+G++ E+ + LP ++IW+LFE+PE+SG A + IVS+++ ++SI FC+ET+P+ + I N Y + FFI ET+C IWF+ E+I R +CP+ + K+ N +DIVA+IPY+ITL L + DGK+G A I + FKL++HS GLQ+L T +AS+ LG+ + + + ++LFSS +Y+ E + K+S +SIPDAFWW V++M TVGYGDMVP ++ G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 34 ERVVINIAGLRFETQLKTLAQFPETLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPANVPLDMFSEEIKFYELGVEAMEKFREDEGFIREEERPLPEKEFQRQIWLLFEHPESSGPARGIAIVSVMVILISIVIFCLETLPELKEDPEGRIKIIGNTTYYYKPSILADPFFIIETLCIIWFSFELIVRFFACPSKAAFFKNMMNTIDIVAIIPYFITLGTELAEEQ--DGKEGKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEKESYFSSIPDAFWWAVVSMTTVGYGDMVPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 411
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Zebrafish
Match: kcna1a (potassium voltage-gated channel, shaker-related subfamily, member 1a [Source:ZFIN;Acc:ZDB-GENE-110408-15]) HSP 1 Score: 335.88 bits (860), Expect = 4.214e-108 Identity = 165/380 (43.42%), Postives = 247/380 (65.00%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSK------MCIDNKNYNF-----LSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXX-------FKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RV IN++GL FET + L + P TLLG+P R ++FD RNEYFFDR+R +F+ I +YY+ G +++RPANVP D+F E+++++L + F D+G++ E+ + LP ++IW+LFE+PE+SG A + IVS+++ ++SI FC+ET+P+ + I N Y + FFI ET+C IWF+ E+I R +CP+ + K+ N +DIVA+IPY+ITL L + DGK+G A I + FKL++HS GLQ+L T +AS+ LG+ + + + ++LFSS +Y+ E + K+S +SIPDAFWW V++M TVGYGDMVP ++ G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 34 ERVVINIAGLRFETQLKTLAQFPETLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPANVPLDMFSEEIKFYELGVEAMEKFREDEGFIREEERPLPEKEFQRQIWLLFEHPESSGPARGIAIVSVMVILISIVIFCLETLPELKEDPEGRIKIIGNTTYYYKPSILADPFFIIETLCIIWFSFELIVRFFACPSKAAFFKNMMNTIDIVAIIPYFITLGTELAEEQ--DGKEGKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEKESYFSSIPDAFWWAVVSMTTVGYGDMVPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 411
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Zebrafish
Match: kcna2a (potassium voltage-gated channel, shaker-related subfamily, member 2a [Source:ZFIN;Acc:ZDB-GENE-131113-1]) HSP 1 Score: 329.717 bits (844), Expect = 8.978e-106 Identity = 159/381 (41.73%), Postives = 247/381 (64.83%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYS-------KMCIDNKNYNFL-------SGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXX-----FKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RV IN+SGL FET + L + P TLLG P R ++FD RNEYFFDR+R +F+ I +YY+ G +++RP NV DVF E+ +++L I F D+G++ E+ + LP N +++W+LFEYPE+SG A + I+S+++ ++SI +FC+ET+P + K+ ++ N FFI ET+C IWF+ E + R +CP+ + + N++D+VA+IPY+ITL L ++ DG++G ++++ + + + FKL++HS GLQ+L T +AS+ LG+ + + + ++LFSS +Y+ E D +S SIPDAFWW V++M TVGYGDMVP ++ G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 32 ERVVINISGLRFETQLKTLSQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVTLDVFSEEIRFYELGDEAIEIFREDEGFIKEEERPLPDNEFQKQVWLLFEYPESSGPARIIAIISVMVILISIVSFCLETLPIFRSDEEEMHKVPVNVNNSTTSYTSTYFTDPFFILETLCIIWFSFEFLVRFFACPSKASFFVNIMNMIDVVAIIPYFITLGTEL-AEKAEDGQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADEPESQFYSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 411
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Zebrafish
Match: kcna2a (potassium voltage-gated channel, shaker-related subfamily, member 2a [Source:ZFIN;Acc:ZDB-GENE-131113-1]) HSP 1 Score: 329.717 bits (844), Expect = 8.978e-106 Identity = 159/381 (41.73%), Postives = 247/381 (64.83%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYS-------KMCIDNKNYNFL-------SGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXX-----FKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RV IN+SGL FET + L + P TLLG P R ++FD RNEYFFDR+R +F+ I +YY+ G +++RP NV DVF E+ +++L I F D+G++ E+ + LP N +++W+LFEYPE+SG A + I+S+++ ++SI +FC+ET+P + K+ ++ N FFI ET+C IWF+ E + R +CP+ + + N++D+VA+IPY+ITL L ++ DG++G ++++ + + + FKL++HS GLQ+L T +AS+ LG+ + + + ++LFSS +Y+ E D +S SIPDAFWW V++M TVGYGDMVP ++ G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 32 ERVVINISGLRFETQLKTLSQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVTLDVFSEEIRFYELGDEAIEIFREDEGFIKEEERPLPDNEFQKQVWLLFEYPESSGPARIIAIISVMVILISIVSFCLETLPIFRSDEEEMHKVPVNVNNSTTSYTSTYFTDPFFILETLCIIWFSFEFLVRFFACPSKASFFVNIMNMIDVVAIIPYFITLGTEL-AEKAEDGQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADEPESQFYSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 411
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Xenopus
Match: KCNA2 (potassium channel, voltage gated shaker related subfamily A, member 3 [Source:NCBI gene;Acc:100496794]) HSP 1 Score: 338.576 bits (867), Expect = 6.654e-109 Identity = 161/385 (41.82%), Postives = 248/385 (64.42%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSKMCID------------------NKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXX-----FKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RV IN+SGL FET + L + P TLLG P R ++FD RNEYFFDR+R +F+ I +YY+ G +++RP NVP D+F E+ +++L + F D+G++ E+ + LP N +++W+LFEYPE+SG A + I+S+++ ++SI +FC+ET+P + D K+ F FFI ET+C IWF+ E + R +CP+ + + N++DIVA+IPY+ITL L ++ DG++G ++++ + + + FKL++HS GLQ+L T +AS+ LG+ + + + ++LFSS +Y+ E D +DS SIPDAFWW V++M TVGYGDMVP ++ G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 33 ERVVINISGLRFETQLKTLSQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEIFREDEGFIKEEERPLPDNEYQKQVWLLFEYPESSGPARIIAIISVMVILISIVSFCLETLPVFRDENEDMHGSGVNYYPYSNSTVRYQKSNTFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTEL-AEKTEDGQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERDSQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 416
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Xenopus
Match: KCNA5 (potassium channel, voltage gated shaker related subfamily A, member 5 [Source:NCBI gene;Acc:496997]) HSP 1 Score: 340.887 bits (873), Expect = 3.838e-108 Identity = 172/420 (40.95%), Postives = 258/420 (61.43%), Query Frame = 1 Query: 472 VAEGHSKSRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKY----------SKMCIDNKNY-----NFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXX--XFKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF---------QSLLKLAVQQNVLTCCGSLMNGVVR 1650 + + S RV IN++GL FET +S L++ P TLLG P R + FD RNEYFFDR+R +F+GI ++Y+ G KI+RP NV DVF E+ +++L + F D+G++ ++ K LP N +++W++FEYPE+S A + IVS+L+ ++SI FC+ET+P++ SK+ D + + FFI ET C IWFT E++ R +CP+ ++ K+ N++DIVA+IPY+ITL L +G++ S + + + IFKL++HS GLQ+L T +AS+ LG+ + + + ++LFSS +Y+ E D +S +SIPDAFWW V+TM TVGYGDM P ++ G+IVGS CA++GVLT+A+ VP+I NFN F Q +LK +C G L R Sbjct: 162 IMDHESNQRVIINIAGLRFETQLSTLNQFPDTLLGDPEKRMRFFDPLRNEYFFDRNRPSFDGILYFYQSGGKIRRPVNVSIDVFADEIRFYELGEEAMERFREDEGFIKDEEKPLPCNEFQRQVWLIFEYPESSSSARGIAIVSVLVILISIITFCLETLPEFRDENELPPALSKVLNDTQEHPSPPSGLTDPFFIIETTCVIWFTFELLVRFFACPSKSDFSKNIMNIIDIVAIIPYFITLGTELAQHQTNNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPESHFSSIPDAFWWAVVTMTTVGYGDMRPVTVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDHEEQVMLKEESSSRQGSCAGDLKRSPSR 581
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Xenopus
Match: KCNA3 (potassium voltage-gated channel subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:6221]) HSP 1 Score: 333.183 bits (853), Expect = 3.939e-107 Identity = 164/381 (43.04%), Postives = 246/381 (64.57%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSKMCIDNKNYN-----------------FLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXX--XFKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RV IN+SGL FET + L + P TLLG P R ++FD RNEYFFDR+R +F+ I +YY+ G +I+RP NVP D+F E+ +++L + F D+G++ E+ + LP N +++W+LFEYPE+SG A + IVS+L+ ++SI FC+ET+P++ D+K Y+ F FF+ ET+C IWF+ E++ R +CP+ + K+ N++DIVA+IPY+ITL L ++ +G++ S + + + IFKL++HS GLQ+L T +AS+ LG+ + + + ++LFSS +Y+ E D S SIPDAFWW V+TM TVGYGDM P ++ G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 22 ERVVINISGLRFETQLKTLAQFPDTLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYELGEEAMEKFREDEGFIREEERPLPPNEFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFR----DDKEYSGTALPPGNGTGPYISSSFTDPFFVVETLCIIWFSFELLVRFFACPSKATFCKNIMNIIDIVAIIPYFITLGTEL-AERQGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPSSGFNSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 397
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Xenopus
Match: KCNA1 (potassium channel, voltage gated shaker related subfamily A, member 1 [Source:NCBI gene;Acc:100492822]) HSP 1 Score: 333.569 bits (854), Expect = 4.290e-107 Identity = 167/375 (44.53%), Postives = 251/375 (66.93%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSKMCIDNKNYN----------FLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXXF---KLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RV INV+GL FET + L + P TLLG+P R ++FD RNEYFFDR+R +F+ I +YY+ G +++RP NVP D+F E+++++L + F D+G++ E+ + LP +++W+LFEYPE+SG A + IVS+++ ++SI FC+ET+P+ I ++ N F FF+ ET+C IWF+ E++ R +CP+ E+ K+ N +DIVA+IPY+ITL + + +SLAILRVIRL+R+F KL++HS GLQ+L T +AS+ LG+ + + + ++LFSS +Y+ E + +S ASIPDAFWW V++M TVGYGDM P ++ G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 34 ERVVINVAGLRFETQLKTLSQFPNTLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFYELGEEAMEKFREDEGFIREEERPLPEKEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVIFCLETLPELKDERIFSRRVNNSTVFYKSNIFTDPFFVVETLCIIWFSFELVVRFFACPSKPEFFKNIMNFIDIVAIIPYFITLGTEMAEQEGPQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEDESHFASIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 408
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Xenopus
Match: ENSXETT00000049277.1 (potassium channel, voltage gated shaker related subfamily A, member 6 [Source:NCBI gene;Acc:100492986]) HSP 1 Score: 328.176 bits (840), Expect = 1.986e-105 Identity = 168/386 (43.52%), Postives = 249/386 (64.51%), Query Frame = 1 Query: 463 RYSVAEGHSKSRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSKMCIDN------------KNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXX--XXFKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 R +A RV IN+SGL FET + L + P TLLG P R + FD RNEYFFDR+R +F+ I +YY+ G +++RP NVP D+FL E+++++L VI F D+G++ E+ + LP N +++W+LFEYPE+SG A + IVS+L+ ++SI FC+ET+P++ + + N F FF+ ET+C IWF+ E++ R +CP+ + K+ NV+DIVA+IPY+ITL L +G++ S + + + RIFKL++HS GLQ+L T QAS+ LG+ + + + ++LFSS +Y+ E D +S SIPDAFWW V++M TVGYGDM P ++ G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 4 RTDLATQDCCERVVINISGLRFETQLRTLSQFPQTLLGDPRKRMRFFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPVDIFLEEIKFYELGEEVIEIFRDDEGFIKEEERPLPENDFQRQVWLLFEYPESSGPARGIAIVSVLIILISIVIFCLETLPEFREEARQSGGQPAVNGTHTFTNSPFTDPFFLTETLCIIWFSFELLVRFFACPSKPAFFKNMMNVIDIVAIIPYFITLGTELAEQQGSNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAETDDPESLFTSIPDAFWWAVVSMTTVGYGDMYPMTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 389
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Mouse
Match: Kcna2 (potassium voltage-gated channel, shaker-related subfamily, member 2 [Source:MGI Symbol;Acc:MGI:96659]) HSP 1 Score: 338.191 bits (866), Expect = 6.658e-109 Identity = 163/385 (42.34%), Postives = 249/385 (64.68%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIP-----------------KYSKMCID-NKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXX-----FKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RV IN+SGL FET + L + P TLLG P R ++FD RNEYFFDR+R +F+ I +YY+ G +++RP NVP D+F E+ +++L + F D+GY+ E+ + LP N +++W+LFEYPE+SG A + IVS+++ ++SI +FC+ET+P YS I ++ +F FFI ET+C IWF+ E + R +CP+ + + N++DIVA+IPY+ITL L ++ D ++G ++++ + + + FKL++HS GLQ+L T +AS+ LG+ + + + ++LFSS +Y+ E D +DS SIPDAFWW V++M TVGYGDMVP ++ G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 33 ERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGGGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTEL-AEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERDSQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 416
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Mouse
Match: Kcna2 (potassium voltage-gated channel, shaker-related subfamily, member 2 [Source:MGI Symbol;Acc:MGI:96659]) HSP 1 Score: 338.191 bits (866), Expect = 6.658e-109 Identity = 163/385 (42.34%), Postives = 249/385 (64.68%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIP-----------------KYSKMCID-NKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXX-----FKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RV IN+SGL FET + L + P TLLG P R ++FD RNEYFFDR+R +F+ I +YY+ G +++RP NVP D+F E+ +++L + F D+GY+ E+ + LP N +++W+LFEYPE+SG A + IVS+++ ++SI +FC+ET+P YS I ++ +F FFI ET+C IWF+ E + R +CP+ + + N++DIVA+IPY+ITL L ++ D ++G ++++ + + + FKL++HS GLQ+L T +AS+ LG+ + + + ++LFSS +Y+ E D +DS SIPDAFWW V++M TVGYGDMVP ++ G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 33 ERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGGGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTEL-AEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERDSQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 416
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Mouse
Match: Kcna2 (potassium voltage-gated channel, shaker-related subfamily, member 2 [Source:MGI Symbol;Acc:MGI:96659]) HSP 1 Score: 338.191 bits (866), Expect = 6.658e-109 Identity = 163/385 (42.34%), Postives = 249/385 (64.68%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIP-----------------KYSKMCID-NKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXX-----FKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RV IN+SGL FET + L + P TLLG P R ++FD RNEYFFDR+R +F+ I +YY+ G +++RP NVP D+F E+ +++L + F D+GY+ E+ + LP N +++W+LFEYPE+SG A + IVS+++ ++SI +FC+ET+P YS I ++ +F FFI ET+C IWF+ E + R +CP+ + + N++DIVA+IPY+ITL L ++ D ++G ++++ + + + FKL++HS GLQ+L T +AS+ LG+ + + + ++LFSS +Y+ E D +DS SIPDAFWW V++M TVGYGDMVP ++ G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 33 ERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGGGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTEL-AEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERDSQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 416
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Mouse
Match: Kcna1 (potassium voltage-gated channel, shaker-related subfamily, member 1 [Source:MGI Symbol;Acc:MGI:96654]) HSP 1 Score: 327.791 bits (839), Expect = 5.695e-105 Identity = 161/385 (41.82%), Postives = 249/385 (64.68%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSKMCIDNKNYN-----------------FLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXX------FKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RV IN+SGL FET + L + P TLLG+P R ++FD RNEYFFDR+R +F+ I +YY+ G +++RP NVP D+F E+++++L + F D+G++ E+ + LP +++W+LFEYPE+SG A + IVS+++ ++SI FC+ET+P+ D+K++ F FFI ET+C IWF+ E++ R +CP+ ++ K+ N +DIVA+IPY+ITL + +G + G L ++R+IR+ FKL++HS GLQ+L T +AS+ LG+ + + + ++LFSS +Y+ E + +S +SIPDAFWW V++M TVGYGDM P ++ G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 37 ERVVINISGLRFETQLKTLAQFPNTLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFYELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILISIVIFCLETLPELK----DDKDFTGTIHRIDNTTVIYTSNIFTDPFFIVETLCIIWFSFELVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAEQ---EGNQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 414
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Mouse
Match: Kcna1 (potassium voltage-gated channel, shaker-related subfamily, member 1 [Source:MGI Symbol;Acc:MGI:96654]) HSP 1 Score: 327.791 bits (839), Expect = 5.695e-105 Identity = 161/385 (41.82%), Postives = 249/385 (64.68%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSKMCIDNKNYN-----------------FLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXX------FKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RV IN+SGL FET + L + P TLLG+P R ++FD RNEYFFDR+R +F+ I +YY+ G +++RP NVP D+F E+++++L + F D+G++ E+ + LP +++W+LFEYPE+SG A + IVS+++ ++SI FC+ET+P+ D+K++ F FFI ET+C IWF+ E++ R +CP+ ++ K+ N +DIVA+IPY+ITL + +G + G L ++R+IR+ FKL++HS GLQ+L T +AS+ LG+ + + + ++LFSS +Y+ E + +S +SIPDAFWW V++M TVGYGDM P ++ G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 37 ERVVINISGLRFETQLKTLAQFPNTLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFYELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILISIVIFCLETLPELK----DDKDFTGTIHRIDNTTVIYTSNIFTDPFFIVETLCIIWFSFELVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAEQ---EGNQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 414
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. UniProt/SwissProt
Match: sp|Q09081|KCNA2_RABIT (Potassium voltage-gated channel subfamily A member 2 OS=Oryctolagus cuniculus OX=9986 GN=KCNA2 PE=1 SV=2) HSP 1 Score: 338.191 bits (866), Expect = 4.095e-108 Identity = 161/385 (41.82%), Postives = 248/385 (64.42%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSKMCID------------------NKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXX-----FKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RV IN+SGL FET + L + P TLLG P R ++FD RNEYFFDR+R +F+ I +YY+ G +++RP NVP D+F E+ +++L + F D+GY+ E+ + LP N +++W+LFEYPE+SG A + IVS+++ ++SI +FC+ET+P + D ++ +F FFI ET+C IWF+ E + R +CP+ + + N++DIVA+IPY+ITL L ++ D ++G ++++ + + + FKL++HS GLQ+L T +AS+ LG+ + + + ++LFSS +Y+ E D +DS SIPDAFWW V++M TVGYGDMVP ++ G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 33 ERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGSGMTFHTYSNSTAGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTEL-AEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERDSQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 416
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. UniProt/SwissProt
Match: sp|P63142|KCNA2_RAT (Potassium voltage-gated channel subfamily A member 2 OS=Rattus norvegicus OX=10116 GN=Kcna2 PE=1 SV=1) HSP 1 Score: 338.191 bits (866), Expect = 4.657e-108 Identity = 163/385 (42.34%), Postives = 249/385 (64.68%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIP-----------------KYSKMCID-NKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXX-----FKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RV IN+SGL FET + L + P TLLG P R ++FD RNEYFFDR+R +F+ I +YY+ G +++RP NVP D+F E+ +++L + F D+GY+ E+ + LP N +++W+LFEYPE+SG A + IVS+++ ++SI +FC+ET+P YS I ++ +F FFI ET+C IWF+ E + R +CP+ + + N++DIVA+IPY+ITL L ++ D ++G ++++ + + + FKL++HS GLQ+L T +AS+ LG+ + + + ++LFSS +Y+ E D +DS SIPDAFWW V++M TVGYGDMVP ++ G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 33 ERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGGGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTEL-AEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERDSQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 416
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. UniProt/SwissProt
Match: sp|P63141|KCNA2_MOUSE (Potassium voltage-gated channel subfamily A member 2 OS=Mus musculus OX=10090 GN=Kcna2 PE=1 SV=1) HSP 1 Score: 338.191 bits (866), Expect = 4.657e-108 Identity = 163/385 (42.34%), Postives = 249/385 (64.68%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIP-----------------KYSKMCID-NKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXX-----FKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RV IN+SGL FET + L + P TLLG P R ++FD RNEYFFDR+R +F+ I +YY+ G +++RP NVP D+F E+ +++L + F D+GY+ E+ + LP N +++W+LFEYPE+SG A + IVS+++ ++SI +FC+ET+P YS I ++ +F FFI ET+C IWF+ E + R +CP+ + + N++DIVA+IPY+ITL L ++ D ++G ++++ + + + FKL++HS GLQ+L T +AS+ LG+ + + + ++LFSS +Y+ E D +DS SIPDAFWW V++M TVGYGDMVP ++ G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 33 ERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGGGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTEL-AEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERDSQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 416
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. UniProt/SwissProt
Match: sp|P16389|KCNA2_HUMAN (Potassium voltage-gated channel subfamily A member 2 OS=Homo sapiens OX=9606 GN=KCNA2 PE=1 SV=2) HSP 1 Score: 336.65 bits (862), Expect = 1.546e-107 Identity = 162/385 (42.08%), Postives = 249/385 (64.68%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIP-----------------KYSKMCID-NKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXX-----FKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RV IN+SGL FET + L + P TLLG P R ++FD RNEYFFDR+R +F+ I +YY+ G +++RP NVP D+F E+ +++L + F D+GY+ E+ + LP N +++W+LFEYPE+SG A + IVS+++ ++SI +FC+ET+P YS I ++ +F FFI ET+C IWF+ E + R +CP+ + + N++DIVA+IPY+ITL L ++ D ++G ++++ + + + FKL++HS GLQ+L T +AS+ LG+ + + + ++LFSS +Y+ E D ++S SIPDAFWW V++M TVGYGDMVP ++ G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 33 ERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTEL-AEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 416
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. UniProt/SwissProt
Match: sp|P22739|KCNA2_XENLA (Potassium voltage-gated channel subfamily A member 2 OS=Xenopus laevis OX=8355 GN=kcna2 PE=1 SV=2) HSP 1 Score: 334.339 bits (856), Expect = 1.170e-106 Identity = 159/385 (41.30%), Postives = 247/385 (64.16%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSKMCID------------------NKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXX-----FKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RV IN+SGL FET + L + P TLLG P R ++FD RNEYFFDR+R +F+ I ++Y+ G +++RP NVP D+F E+ +++L + F D+G++ E+ + LP N +++W+LFEYPE+SG A + I+S+ + ++SI +FC+ET+P + D K+ F FFI ET+C IWF+ E + R ++CP+ + + N++DIVA+IPY+ITL L ++ DG++G ++++ + + + FKL++HS GLQ+L T AS+ LG+ + + + ++LFSS +++ E D +DS SIPDAFWW V++M TVGYGDMVP ++ G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 33 ERVVINISGLRFETQLKTLSQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYFYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEIFREDEGFIKEEERPLPDNEFQKQVWLLFEYPESSGPARIIAIISVTVILISIVSFCLETLPVFRDENEDMHGSGGNYYSYPNSTVRFQKSNTFTDPFFIVETLCIIWFSFEFLVRFLACPSKAVFFTNLMNIIDIVAIIPYFITLGTEL-AEKTEDGQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLNASMRELGLLIFFLFIGVILFSSAVFFAEADERDSQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 416
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. TrEMBL
Match: A0A267H803 (BTB domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig000942g2 PE=3 SV=1) HSP 1 Score: 431.795 bits (1109), Expect = 5.147e-142 Identity = 208/362 (57.46%), Postives = 282/362 (77.90%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIKLPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKY-SKMCIDNKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXXFKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RVR+NVSG+ FET + L++HP TLLG+P R ++FD R +EYFFDRHR FE IF+YY+YG K+KRP NV +D+FLSE+E++++E VI+ + D+GY+ E + LP +P+ +KIW+LFEYPETS A+ V I+S+L T++SI FC+ET+ ++ C+ ++ NFL FFI E+ CT WFT+E++ R CP+ K ++KD KN +D A++PYY+TL N+L + +C +G K +SLA LRV+RLIR+FKLTKH GLQVL+LTF+AS+ GLG+FL+A++V +LLFSSTIYY+E +VK S I SIPDAFWW VITMCTVGYGD VPK +G +VGS CA++GVLTLA+ VPII+ENFNKF Sbjct: 132 ERVRLNVSGMHFETRLGVLNQHPRTLLGNPQKRAKYFDRRHHEYFFDRHRPTFEAIFNYYQYGGKLKRPPNVTDDIFLSELEFYEIEREVIDAYKKDEGYISETVVLPEHPVKRKIWMLFEYPETSTPAFLVAIISVLFTVISIILFCVETLKEFKDSHCVAHELPNFLDPFFIIESACTAWFTLELVIRFAVCPSKKAFIKDIKNAVDFSAIVPYYVTLTNVLITMSC-EGAKSSASLAFLRVVRLIRVFKLTKHFDGLQVLVLTFRASIEGLGLFLVALIVCILLFSSTIYYVEAEVKGSQIESIPDAFWWAVITMCTVGYGDKVPKGPLGMVVGSVCAIAGVLTLAIPVPIITENFNKF 492
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. TrEMBL
Match: A0A267DW52 (BTB domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig000942g3 PE=3 SV=1) HSP 1 Score: 431.409 bits (1108), Expect = 7.850e-142 Identity = 208/362 (57.46%), Postives = 282/362 (77.90%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIKLPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKY-SKMCIDNKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXXFKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RVR+NVSG+ FET + L++HP TLLG+P R ++FD R +EYFFDRHR FE IF+YY+YG K+KRP NV +D+FLSE+E++++E VI+ + D+GY+ E + LP +P+ +KIW+LFEYPETS A+ V I+S+L T++SI FC+ET+ ++ C+ ++ NFL FFI E+ CT WFT+E++ R CP+ K ++KD KN +D A++PYY+TL N+L + +C +G K +SLA LRV+RLIR+FKLTKH GLQVL+LTF+AS+ GLG+FL+A++V +LLFSSTIYY+E +VK S I SIPDAFWW VITMCTVGYGD VPK +G +VGS CA++GVLTLA+ VPII+ENFNKF Sbjct: 132 ERVRLNVSGMHFETRLGVLNQHPRTLLGNPQKRAKYFDRRHHEYFFDRHRPTFEAIFNYYQYGGKLKRPPNVTDDIFLSELEFYEIEREVIDAYKKDEGYISETVVLPEHPVKRKIWMLFEYPETSTPAFLVAIISVLFTVISIILFCVETLKEFKDSHCVAHELPNFLDPFFIIESACTAWFTLELVIRFAVCPSKKAFIKDIKNAVDFSAIVPYYVTLTNVLITMSC-EGAKSSASLAFLRVVRLIRVFKLTKHFDGLQVLVLTFRASIEGLGLFLVALIVCILLFSSTIYYVEAEVKGSQIESIPDAFWWAVITMCTVGYGDKVPKGPLGMVVGSVCAIAGVLTLAIPVPIITENFNKF 492
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. TrEMBL
Match: A0A210PGX2 (Potassium voltage-gated channel subfamily A member 1 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT03312 PE=3 SV=1) HSP 1 Score: 425.631 bits (1093), Expect = 2.827e-140 Identity = 209/361 (57.89%), Postives = 279/361 (77.29%), Query Frame = 1 Query: 496 RVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIKLPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSKM-CIDNKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXXFKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 R INVSG +E W + ++RHPTTLLG+P R ++FD RRNE+FFDRHR FE IF+YY YG KI+RP VP+D+FL E++++++E V++ + ++GY+ EK++LP + +KIW+L EYPETS YAY V IVS+++T++SI FC+ET+P S CID + NF+ FFI ET+CTIWFT+E++ RL SCP+ +Y KD KN++DI A++PYYI+L+N+L C D G+SLA LRV+RL+RIFKLTKHS GLQVLILTF+AS+ GL +FL+AM+V +LLFSS IYY E + D+ I SIPD FWW VITMCTVGYGD VP +G+++GS CA++GVLTLA+ VPII+ENFNKF Sbjct: 81 RFTINVSGQYYELWATLVNRHPTTLLGNPRKRLKYFDKRRNEFFFDRHRPTFESIFNYYMYGGKIRRPEPVPDDIFLRELDFYEIEKEVVDLYKDEEGYIQEKMELPDSKWKRKIWMLMEYPETSPYAYVVAIVSVVITLLSIVLFCVETLPSLSGSDCIDGRP-NFMEPFFIMETVCTIWFTLEVVIRLFSCPSKIKYFKDFKNIVDITAIVPYYISLSNLLAPAGC-DSASSGASLAFLRVVRLVRIFKLTKHSAGLQVLILTFKASIQGLMLFLVAMVVCVLLFSSAIYYAEHGIPDAQIKSIPDGFWWAVITMCTVGYGDKVPVGPLGKLIGSVCALAGVLTLAIPVPIITENFNKF 439
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. TrEMBL
Match: A0A2H1CQP4 (K+ channel tetramerization domain protein OS=Fasciola hepatica OX=6192 GN=D915_002281 PE=3 SV=1) HSP 1 Score: 431.024 bits (1107), Expect = 8.358e-138 Identity = 219/413 (53.03%), Postives = 293/413 (70.94%), Query Frame = 1 Query: 352 MSNTFNFTHNYRYREFLSSTSSTPGEIAPFNDVNKFNRYSVAEGHSK----SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIKLPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSKM-CIDNKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXXFKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 + F + + FL S P +P N+F S + RV +NVSGL FETW++ L+ HPTTLLG R +D +R EYFFDRHR +FE IF+YY+YG +IKRPA V +D+FL E+E+F++E + + + ++GYV E I LP N + +K+W+LFEYPETS A+ + S++ T++SI FC+ET+P Y++ C NF FFI ETICTIWFT E+I R VSCP+ K+++KD KN++D+ A++PYYITL N+L + +C +G K +SLA LRVIRLIR+FKLTKHS+GLQVL+LTF+ S+ GL +FL+A +V +L+FSS +YY+E+D K S I SIPDAFWW VITMCTVGYGD VPK +G+IVGS CAV+GVLTLA+ VPII+ENFNKF Sbjct: 372 LRRAFGLDGHMKNNPFLLSGQEVPESGSPVILANEFEPSSSNNSETVCQDCQRVILNVSGLKFETWLAVLNNHPTTLLGDADKRMPFYDEQRKEYFFDRHRPSFEAIFNYYQYGGRIKRPAVVADDIFLRELEFFQIEKDALESYKKNEGYVPEVIILPENRIKRKLWLLFEYPETSPLAFCFSVTSVIFTVISIILFCVETLPVYAQTHCEPGAKPNFRDPFFIIETICTIWFTFELIIRFVSCPSHKKFIKDLKNLIDLAAIVPYYITLTNVLITFSC-EGAKSSASLAFLRVIRLIRVFKLTKHSSGLQVLVLTFKESIEGLSLFLVAFIVCILVFSSVLYYVEIDRKGSQIESIPDAFWWAVITMCTVGYGDKVPKGPLGKIVGSVCAVAGVLTLAIPVPIITENFNKF 783
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. TrEMBL
Match: A0A5J4P1R6 (BTB domain-containing protein OS=Paragonimus westermani OX=34504 GN=DEA37_0000340 PE=3 SV=1) HSP 1 Score: 429.869 bits (1104), Expect = 2.739e-137 Identity = 214/361 (59.28%), Postives = 279/361 (77.29%), Query Frame = 1 Query: 496 RVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIKLPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSKM-CIDNKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXXFKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RV +NVSGL FETWI+ L+ HPTTLLG+ R+ +DS RNEYFFDRHR +FE IF+YY+YG ++KRPA V +DVFLSE+E+F++E + + + +GYV E I LP P +++W+LFEYPETS A+ + S++ TI+SI FC+ET+P Y+ C + NFL FFI ET CTIWFT E+ R +SCP+ + ++KD KN++D+ A++PYYITL N+L S +C +G K +SLA LRVIRLIR+FKLTKHS+GLQVL+LTF+ S+ GL +FL+A +V +L+FSSTIYY+E+D K S I SIPDAFWW VITMCTVGYGD VPK +G+IVGS CAV+GVLTLA+ VPII+ENFNKF Sbjct: 435 RVVLNVSGLRFETWIAVLNNHPTTLLGNSIKRRPFWDSYRNEYFFDRHRPSFEAIFNYYQYGGRLKRPAVVADDVFLSEVEFFEIEADAVESYKKGEGYVPEVIVLPEKPWKRRLWLLFEYPETSLLAFCFSVASVIFTIVSIILFCVETLPIYADTHCKLEEAPNFLDPFFIIETACTIWFTFELTIRFISCPSQRSFIKDIKNLIDLAAIVPYYITLINVLISYSC-EGAKNSASLAFLRVIRLIRVFKLTKHSSGLQVLVLTFKESVEGLSLFLVAFIVCILVFSSTIYYVEIDRKGSQIESIPDAFWWAVITMCTVGYGDKVPKGPLGKIVGSVCAVAGVLTLAIPVPIITENFNKF 794
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Cavefish
Match: kcna2b (potassium voltage-gated channel subfamily A member 2 [Source:NCBI gene;Acc:103039676]) HSP 1 Score: 337.421 bits (864), Expect = 8.836e-109 Identity = 164/381 (43.04%), Postives = 248/381 (65.09%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSKMCID-NKNY-------------NFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXX-----FKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RV IN+SGL FET + L + P TLLG P R ++FD RNEYFFDR+R +F+ I +YY+ G +++RP NV D+F E+ +++L I F D+G++ E+ K LP N +++W+LFEYPE+SG A + I+S+++ ++SI +FC+ET+P + ID K Y F FFI ET+C IWF+ E + R +CP+ + + N++DIVA+IPY+ITL L +++ DG++G ++++ + + + FKL++HS GLQ+L T +AS+ LG+ + + + ++LFSS +Y+ E D DS SIPDAFWW V++M TVGYGDMVP ++ G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 32 ERVVINISGLRFETQLKTLSQFPDTLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVTLDIFSEEIRFYELGEEAIEIFREDEGFIKEEEKPLPENEFQRQVWLLFEYPESSGPARIIAIISVMVILISIVSFCLETLPIFRNDDIDMRKTYPGNSNSTTSYTSTYFTDPFFILETLCIIWFSFEFLVRFFACPSKAGFFVNIMNIIDIVAIIPYFITLGTEL-AESPEDGQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADEADSQFVSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 411
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Cavefish
Match: kcna1a (potassium voltage-gated channel subfamily A member 1 [Source:NCBI gene;Acc:103039047]) HSP 1 Score: 334.339 bits (856), Expect = 1.060e-107 Identity = 163/378 (43.12%), Postives = 247/378 (65.34%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSK------MCIDNKNYNF-----LSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSD-NCIDGKKGGSSXXXXXXXXXXXX----FKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RV IN++GL FET + L + P TLLG+P R ++FD RNEYFFDR+R +F+ I +YY+ G +++RPA+VP D+F E+++++L + F D+G++ EK + LP ++IW+LFE+PE+SG A + IVS+ + ++SI FC+ET+P+ + I N + + FFI ET+C IWF+ E+I R ++CP+ + KD N +D+VA+IPY+ITL L D N DGK ++ + + + FKL++HS GLQ+L LT +AS+ LG+ + + + ++LFSS +Y+ E + DS SIPDAFWW V++M TVGYGDMVP ++ G++VGS CA++GVLT+A+ VP+I NFN F Sbjct: 34 ERVVINIAGLRFETELKTLAQFPETLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPASVPLDMFSEEIKFYELGYEAMEKFREDEGFIREKERPLPEAEFQRQIWLLFEHPESSGPARGIAIVSVTVILVSIVIFCLETLPQLKENPEGHIQIIGNSTFYYKPSLLTDPFFIVETLCIIWFSFELIVRFLACPSKAAFFKDMMNTIDVVAIIPYFITLGTELAEDPNNKDGKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGLTLKASMRELGLLVFFLFIGVILFSSAVYFAEAEEADSYFGSIPDAFWWAVVSMTTVGYGDMVPVTIGGKVVGSLCAIAGVLTIALPVPVIVSNFNYF 411
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Cavefish
Match: kcna2a (potassium voltage-gated channel subfamily A member 2 [Source:NCBI gene;Acc:103030675]) HSP 1 Score: 331.257 bits (848), Expect = 2.175e-106 Identity = 160/390 (41.03%), Postives = 248/390 (63.59%), Query Frame = 1 Query: 475 AEGHSKSRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSKMCIDNKNYN-----------------FLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXX-----FKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 AE RV IN+SGL FET + L + P TLLG P R ++FD RNEYFFDR+R +F+ I +YY+ G +++RP NV D+F E+ +++L I F D+G++ E+ + LP N +++W+LFEYPE+SG A + I+S+++ ++SI +FC+ET+P + D + + F FFI ET+C IWF+ E + R +CP+ + + N++D+VA+IPY+ITL L ++ DG++G ++++ + + + FKL++HS GLQ+L T +AS+ LG+ + + + ++LFSS +Y+ E D +S SIPDAFWW V++M TVGYGDMVP ++ G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 26 AEQECCERVVINISGLRFETQLKTLSQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVTLDIFSEEIRFYELGEEAIEMFREDEGFIKEEERPLPDNEFQKQVWLLFEYPESSGPARIIAIISVMVILISIVSFCLETLPIFRS---DEEEMHKVRTYNSNSTTSYTSTYFTDPFFILETLCIIWFSFEFLVRFFACPSKASFFVNIMNMIDVVAIIPYFITLGTEL-AEKAEDGQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADEPESQFYSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 411
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Cavefish
Match: KCNA3 (potassium voltage-gated channel subfamily A member 3 [Source:NCBI gene;Acc:103031324]) HSP 1 Score: 330.872 bits (847), Expect = 8.071e-106 Identity = 168/416 (40.38%), Postives = 257/416 (61.78%), Query Frame = 1 Query: 394 EFLSSTSSTPGEIAPFNDVNKFNRYSVAEGHSKSRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSK--------------MCIDNKNYNFLSG-----FFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXX--XXFKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 E L + + P ++ RY G RV IN+SGL FET + + P TLLG P R ++FD RNEYFFDR+R +F+ I +YY+ G +I+RP NVP DVF E+ +++L + F D+G++ E+ + LPS +++W+LFEYPE+SG A + IVS+L+ ++SI FC+ET+P++ + ++N + G FF+ ET+C +WF+ E++ R +CP+ + K+ N++DIVA+IPY+ITL L ++ +G++ S + + + RIFKL++HS GLQ+L T +AS+ LG+ + + + ++LFSS +Y+ E D S +SIPDAFWW V+TM TVGYGDM P ++ G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 43 ELLEESGALPAHVS-------LERYEPEPG-CHERVVINISGLRFETQLKTFSQFPDTLLGDPRKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDVFSEEIRFYQLGEEAMEKFREDEGFIKEEERPLPSREFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDDREAAAAAAAAAAAVPLNNGTAPYGPGAFTDPFFVIETLCIVWFSFELLVRFFACPSKATFSKNIMNIIDIVAIIPYFITLGTEL-AERQGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPASSFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 449
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Cavefish
Match: ENSAMXT00000027012.2 (potassium voltage-gated channel subfamily A member 2-like [Source:NCBI gene;Acc:103027793]) HSP 1 Score: 320.472 bits (820), Expect = 1.016e-101 Identity = 164/414 (39.61%), Postives = 247/414 (59.66%), Query Frame = 1 Query: 451 NKFNRYSVAEGHSKSRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKY--------------SKMCIDNKNYNFLSG--------------------FFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXX----FKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 N +RY E RV IN+SGL FET + L + P TLLG P R +FD RNEYFFDR+R +F+ I +YY+ G +++RP NVP DVF E+ +++L + F D+G++ E+ + LP+ +++W+LFEYPE+SG A + IVS+L+ ++SI FC+ET+P++ + + + N N + G FF+ ET+C +WF+ E++ R +CP+ + K+ N++DIVA+IPY+ITL L +G + + + + FKL++HS GLQ+L T +AS+ LG+ + + + ++LFSS +Y+ E D DS SIPDAFWW V+TM TVGYGDM P ++ G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 63 NAVDRYE-PEHECCERVVINISGLRFETQLKTLAQFPETLLGDPRKRTAYFDPLRNEYFFDRNRPSFDAILYYYQSGGRVRRPVNVPIDVFTEEIRFYELGEEAMEKFREDEGFIKEEERALPAGEFQRQVWLLFEYPESSGPARGIAIVSVLVILVSIVIFCLETLPEFRDDDSDVTRDRVGTTPLHMLNHYPNEMHGHGNLTGGLPPILSGTPFSDPFFVVETLCIVWFSFELLVRFFACPSKATFSKNIMNIIDIVAIIPYFITLGTELAERQQGNGGGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPDSGFNSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 475
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Sea Lamprey
Match: KCNA3 (potassium voltage-gated channel subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:6221]) HSP 1 Score: 316.62 bits (810), Expect = 1.199e-101 Identity = 165/383 (43.08%), Postives = 249/383 (65.01%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSKMCIDNKNYNFLSG-------------------FFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXX--XXFKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 R+ INVSGL FET + LD+ P TLLG+P+ R ++FD RNEYFFDR+R +F+ I +YY+ G +++RP NV DVF E+++++L + F D+G++ E+ K LPS+ +++W+LFEYPE+S A + IVS+L+ ++SI FC+ET+P++ D K FL FFI ETIC IWF+ E++ R +CP+ + K N++DIVA++PY+ITL + + + G++ S + + + RIFKL++HS GLQ+L T +AS+ LG+ + + + ++LFSS +Y+ E D ++S+ SIPDAFWW V+TM TVGYGDM P ++ G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 28 ERIVINVSGLRFETQLKSLDQFPDTLLGNPSKRSRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVSIDVFSEEIKFYELGNEAMAKFQEDEGFIKEEEKPLPSDEFQRQVWLLFEYPESSNPARGIAIVSVLVILISIIIFCLETLPEFR----DEKEQKFLPAKDINGTQVKIMHGSSFTDPFFIVETICIIWFSFELLVRFFACPSKPGFFKSIMNIIDIVAILPYFITLGTEM-AKHQGSGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADHQNSEFRSIPDAFWWAVVTMTTVGYGDMRPVTVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 405
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Sea Lamprey
Match: KCNA3 (potassium voltage-gated channel subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:6221]) HSP 1 Score: 316.235 bits (809), Expect = 4.425e-101 Identity = 170/391 (43.48%), Postives = 251/391 (64.19%), Query Frame = 1 Query: 460 NRYSVAE--GHS-KSRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSKMCIDNKNYNFLSG------------FFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLA-NMLFSDNCIDGKKGGSSXXXXXXXXXX--XXFKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RY +A GH RV INVSGL FET + L + P TLLG P R ++FD RNEYFFDR+R +F+ I +YY+ G +++RP +VP D+F E+ ++ L + + D+GYV E K LP N +++W+LFEYPE+S A A+ IVS+L+ ++SI FC+ET+P++ K + +G FFI ETIC IWF+ E++ R +CP+ E+ K+ N++DIVA++PY+ITL M +G++ S + + + RIFKL++HS GLQ+L T AS+ LG+ + + + ++LFSS +++ EVD K ++ SIPDAFWW ++TM TVGYGDM PK++ G+IVGS CA++GVLT+++ VP+I NFN F Sbjct: 24 ERYELARPGGHDFCERVVINVSGLRFETQLRTLAQFPDTLLGDPQKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVSVPYDIFTEEVRFYDLGEETMLRYREDEGYVKEPEKPLPENEFQRQVWLLFEYPESSSPARAIAIVSVLVILISIIIFCLETLPEFRDDADLYKVSYYTNGTHYFYHNVFADPFFIMETICIIWFSFELMVRFCACPSKVEFGKNLMNIIDIVAIVPYFITLGTEMAEQTGSANGQQTMSLAILRVIRLVRVFRIFKLSRHSKGLQILGHTLHASMRELGLLIFFLFIGVILFSSAVFFAEVDSKKTEFQSIPDAFWWSLVTMTTVGYGDMSPKTVGGKIVGSLCAIAGVLTVSLPVPVIVSNFNYF 414
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Sea Lamprey
Match: KCNA3 (potassium voltage-gated channel subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:6221]) HSP 1 Score: 276.944 bits (707), Expect = 4.293e-87 Identity = 156/395 (39.49%), Postives = 236/395 (59.75%), Query Frame = 1 Query: 538 ISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSKMCIDNKNYN------------------------------FLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXX------FKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKFQSLLKLAVQQNV 1611 + L P TLLG P R ++FD RNEYFFDR+R +F+ I +YY+ K++RP NVP D+F E+ +++L + + D+GYV E+ K LP N L +++W+LFEYPE+S A + IVS+L+ ++SI F ET+P++ D+K+ + FFI ET+C +WF+ E++ R +CP+ + K+ N +DIVA++PY+ITL L + + G G L ++R+IR+ FKL++HS GLQ+L T +AS+ LG+ + + + ++LFSS IY+ EVD ++ SIP+AFWW ++TM TVGYGDM P +L G+IVGS CA++GVLT+A+ VP+I NFN F A +Q + Sbjct: 2 LRTLAHFPDTLLGDPQKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSRGKLRRPTNVPYDIFAEEVRFYELGEETMARYREDEGYVKEEEKPLPENALQRQVWLLFEYPESSNPARVIAIVSVLVIVISIVIFVAETLPEFR----DDKDLHSGTRHDVGAGDAAVAAAGNSSGGSSGGGSGHADPFFIVETVCIVWFSFELLVRFCACPSKPGFFKNIMNTIDIVAIMPYFITLGTELAAQDT--GANNGQQTMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFIGVILFSSAIYFAEVDDPNTHFHSIPEAFWWSLVTMTTVGYGDMFPVTLGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRGSEAEEQTL 390
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Sea Lamprey
Match: kcna1b (potassium voltage-gated channel, shaker-related subfamily, member 1b [Source:ZFIN;Acc:ZDB-GENE-140515-1]) HSP 1 Score: 274.248 bits (700), Expect = 1.259e-86 Identity = 148/374 (39.57%), Postives = 223/374 (59.63%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIKLPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSK----------MCIDNKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXXFKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKFQSL 1584 RV INVSG FET + LD+ P +LLG P R ++FD +NEYFFDR F+ I YY+ G ++ +P +VP DVF E+E+++L + + + E+ + Q +W LFE + S A + ++S + TI+SIT C+ET+P++ K I YN L FF+ ET C +WF E+ R +CP+ +MKD N +DI+A++PY+IT+ + + L I+R++R++RIFKL++H LQ+L LT +ASL L + + V++++FS IYY+E D +SIPDAFWW V+TM VGYGDM P ++ G+IVG+ CA++GVLT+++ VP+I NF F +L Sbjct: 1 QRVVINVSGERFETQLKTLDQFPDSLLGHPDKRARYFDPLQNEYFFDRSHVNFDAILFYYQSGGRLCKPVDVPSDVFREEVEFYELGEEAVAKYGENTLDTPEEENVHGKDFQQHVWRLFESRDGSIAAKMLSLMSFVTTILSITVMCLETLPQFRKDNQVHANRTEFSIRTSIYN-LDPFFMLETACVVWFIFELAVRFYACPSKTSFMKDFMNAIDILAIMPYFITVVLEIMQQQ---DQTRQPLLKIIRLVRVLRIFKLSRHCQDLQILGLTLKASLRELAMLSFFLFVAVVIFSGAIYYVEADDPQKHFSSIPDAFWWAVVTMTLVGYGDMWPMTVGGKIVGALCAITGVLTISLPVPVIVSNFKYFYNL 370
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Sea Lamprey
Match: kcna1b (potassium voltage-gated channel, shaker-related subfamily, member 1b [Source:ZFIN;Acc:ZDB-GENE-140515-1]) HSP 1 Score: 274.248 bits (700), Expect = 1.479e-86 Identity = 148/374 (39.57%), Postives = 223/374 (59.63%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIKLPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSK----------MCIDNKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXXFKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKFQSL 1584 RV INVSG FET + LD+ P +LLG P R ++FD +NEYFFDR F+ I YY+ G ++ +P +VP DVF E+E+++L + + + E+ + Q +W LFE + S A + ++S + TI+SIT C+ET+P++ K I YN L FF+ ET C +WF E+ R +CP+ +MKD N +DI+A++PY+IT+ + + L I+R++R++RIFKL++H LQ+L LT +ASL L + + V++++FS IYY+E D +SIPDAFWW V+TM VGYGDM P ++ G+IVG+ CA++GVLT+++ VP+I NF F +L Sbjct: 5 QRVVINVSGERFETQLKTLDQFPDSLLGHPDKRARYFDPLQNEYFFDRSHVNFDAILFYYQSGGRLCKPVDVPSDVFREEVEFYELGEEAVAKYGENTLDTPEEENVHGKDFQQHVWRLFESRDGSIAAKMLSLMSFVTTILSITVMCLETLPQFRKDNQVHANRTEFSIRTSIYN-LDPFFMLETACVVWFIFELAVRFYACPSKTSFMKDFMNAIDILAIMPYFITVVLEIMQQQ---DQTRQPLLKIIRLVRVLRIFKLSRHCQDLQILGLTLKASLRELAMLSFFLFVAVVIFSGAIYYVEADDPQKHFSSIPDAFWWAVVTMTLVGYGDMWPMTVGGKIVGALCAITGVLTISLPVPVIVSNFKYFYNL 374
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Nematostella
Match: SHAK4 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHB6]) HSP 1 Score: 297.745 bits (761), Expect = 1.187e-94 Identity = 170/380 (44.74%), Postives = 237/380 (62.37%), Query Frame = 1 Query: 481 GHSKSRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGF-HHDQGYVFEKIKLPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSK-------------MCIDNKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXX-XXFKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 G + R+ INVSGL FET + L+ +P TLLG+ R +++DS RNEYFFDR+R AF+ I YY+ G K+ RPANVP DVF E+ +++L +V++ + EK LP N L ++IW LFE+P+TS A V I S+ + +SI FCIET+P++ K + +DN+ F +F ET C IWFT E I RL+S P +++ N++DIVA++PYYITL D K + + + + RIFKL++HS GLQ+L T +ASL LG+ + +L+ ++LFSS +YY E K + SIPDAFWW V+TM TVGYGDM P ++ G+IVGS CA+SGVLT+A+ VP+I NFN F Sbjct: 54 GEATDRILINVSGLKFETHVQTLESNPDTLLGNAVKRAKYYDSVRNEYFFDRNRPAFDAILFYYQSGGKLLRPANVPMDVFADEIRFYELGDDVLHKVEQEEGYIEEEKPILPENKLQRQIWQLFEFPDTSMPARFVAIFSVFVITLSIVTFCIETLPQFQKKEEDLYVSVNGTLVPVDNR---FDQPWFSMETACIIWFTFEYIMRLISSPQKLIFIRSFLNMIDIVAILPYYITLPMQ-------DTKASSLGVLRVIRLVRVFRIFKLSRHSRGLQILGHTLRASLRELGLLIFFLLIGVILFSSAVYYAEGGEKGTHFKSIPDAFWWAVVTMTTVGYGDMRPITVWGKIVGSLCAISGVLTIALPVPVIVSNFNYF 423
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Nematostella
Match: SHAK3 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SK45]) HSP 1 Score: 267.7 bits (683), Expect = 9.441e-84 Identity = 157/379 (41.42%), Postives = 233/379 (61.48%), Query Frame = 1 Query: 496 RVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYS-KMCIDNKNYNFL-----------------SGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXXFKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 R+ INVSGL FET+ + L + P TLLGS + R+++FDS +EYFFDR+R FE I +Y+ K+ RP+ VP +F E+ +FKL + + ++GY+ E + LP + L ++IW LFEYP++S A + + S+ + ++SI FCIET+P + K D L S + E +C WFT+E + RL+S P +++ NV+D++A++PYYITL + + L ++R++R+ RIFKL++HS GLQVL T +AS L + + +L+S++LFSS +YY E + S +SIPDAFWW V+TM TVGYGDM P + G++VGS CA+SGVLT+A+ VP+I NFN F Sbjct: 2 RIIINVSGLRFETYEATLAQFPNTLLGSESKREEYFDSDADEYFFDRNRSTFEAILFFYQSNGKLVRPSGVPFLLFKDEVIFFKLGKDNLKRLEEEEGYIEETTRVLPRHHLQRRIWELFEYPDSSMGARVLAVWSVSVILISIVVFCIETLPTFRCKTSPDGNGCPKLLPGTNSTADHPEPVEKSSAWLALEILCIAWFTLEYVVRLLSSPQKLLFVRSFLNVIDLMAILPYYITLPMKDLRITSL------AVLRVIRLVRVFRIFKLSRHSRGLQVLGHTLRASSRELAMLIFFLLISVVLFSSAVYYAEEEEAASKFSSIPDAFWWAVVTMTTVGYGDMYPVTPWGKLVGSICAISGVLTIALPVPVIVSNFNYF 374
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Nematostella
Match: SHAK6 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFM4]) HSP 1 Score: 266.929 bits (681), Expect = 1.223e-83 Identity = 151/380 (39.74%), Postives = 230/380 (60.53%), Query Frame = 1 Query: 496 RVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSK-------------MCIDNKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXX---XXXXXXXXXFKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDV-KDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKFQS 1581 R+ IN+SGL +ET+ L+R P +LLG + R +DS +EYFFDR+R FE I YY+ + RP N+P VF+S+++YF L + D +I+ +P N + +W LFE+P+TS A A+ I S+ + ++SI FC+ET+P++ + + IDN S FF E+ C WFT+E R + P+ +++ N++D+VA++P++ITL + SSLAI +R++R+ RIFKL+++S GLQ+L T +ASL LG+ + V ++LFSS +YY E + +D++ SIP +FWW +ITM TVGYGDM PK+L G++VG FCA+SGVL +A+ VP+I NF + S Sbjct: 2 RITINISGLRYETFDKTLERFPESLLGCKSRRDDFYDSVNDEYFFDRNRLCFESILAYYQTCGVLIRPPNIPRKVFVSDIKYFDLGEQALRQAGDDLEITDREIRPMPKNKFQRTVWSLFEHPDTSNGARAIAIFSVAVIVLSIVLFCVETLPQFQRRPKEVLRNNITETIMIDNPKK---SVFFAIESFCIAWFTLEYFIRFLCSPDKCKFVVSVLNLIDLVAILPFFITLP--------MTEPTSVSSLAILRCVRLVRVFRIFKLSRYSRGLQILGHTLKASLRELGLLFFFLCVGVILFSSAVYYAEYNYNRDTEFLSIPHSFWWSIITMTTVGYGDMAPKTLGGKLVGCFCAISGVLAIALPVPVIVSNFAYYYS 370
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Nematostella
Match: SHAK5 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SAS8]) HSP 1 Score: 264.233 bits (674), Expect = 1.659e-82 Identity = 145/383 (37.86%), Postives = 228/383 (59.53%), Query Frame = 1 Query: 496 RVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHH---DQGYVFEKIKLPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSKMCIDNKN---------------------YNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXXFKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIA-SIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFN 1569 RV +NVSG ++T++ LD+ PTTLLG P R+++FD NEYFFDR++Q FE I ++Y+ ++ P ++ ++ L E+E+F L IN D+ +P+N + + W LFEY ++S A + + S+ + + SI C+ET+P ++ + I + N + +L FI WFT+E + R +S P +++ NV+DI+A++P+YI L +L S DG + L ILR++R+ RIFKL++HS+GLQ+L LT + SL LG+ + + + +++FSS YY E KD+ + SIPD FWW ++TM TVGYGD+VPK+L G++VGS CA+ GVL +A+ VP+I NF+ Sbjct: 1 RVTLNVSGFRYQTYVETLDKFPTTLLGDPAKRREYFDPDLNEYFFDRNKQVFEIILYFYQSNGRLVCPPDLAPEILLEEVEFFDLGETAINAVKELLTDEEPDETPRDMPTNKIQTQFWNLFEYADSSKAARVIALFSVSIIVASIAVLCVETLPNFAILPIHDPNNTEEVRRVNKHNEGAILARRWFGYLEAAFIA------WFTLEYLVRFLSSPKKCPFVRSFLNVIDILAIVPFYIDL--ILNSVQSNDGTLSLAFLRILRLVRVFRIFKLSRHSSGLQILGLTLRKSLRELGLLIFFLFIGVVIFSSMAYYAEAGTKDTHLGRSIPDTFWWALVTMTTVGYGDLVPKTLWGKLVGSCCALCGVLAIALPVPVIVSNFD 375
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Nematostella
Match: SHAK1 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SK44]) HSP 1 Score: 259.996 bits (663), Expect = 5.076e-81 Identity = 143/371 (38.54%), Postives = 221/371 (59.57%), Query Frame = 1 Query: 499 VRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK--LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSKMCIDN-KNYN---------FLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXXFKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 + INVSG FET+ L R P TLLG P R + ++++ EYFFDRHR AF+ I +YY+ G + RP +VP VF++E+ ++ L + D G E + LP N L+ +W EYPE S A + I S+++ ++S+ FC+ET+P++ + KN + +F T +WFT E I RL+ P +++ N++D+++++PYY+ LA G S L ++RV+R+ R+FKL++HS GLQ+L T +AS+N L + + + + +++F+S +YY E + DS SIP +FWW V+TM TVGYGD+ P+S G+IVG+ CA+SGVLT+A+ VP+I NF F Sbjct: 3 IVINVSGKRFETYEETLARFPDTLLGCPARRAKFLNNKKGEYFFDRHRSAFDAILYYYQAGGSLIRPEHVPPHVFINEVIFYDLPEEALQSVQLDAGIADEPEEKVLPKNQYLRYVWETLEYPEYSKLAKFLAIFSVVVIVLSLIIFCVETLPEFMPQEVTKPKNATADWKPPKDPYEETWFQLNTFVIVWFTAEYILRLICSPEKLKFLLAALNIIDLLSILPYYVQLA-------LDSGSSSISVLRVVRVVRVFRVFKLSRHSRGLQILGNTLRASMNELMMLMFFLFIGVMIFASCVYYAEGGI-DSPFRSIPHSFWWAVVTMTTVGYGDISPESFWGKIVGALCAISGVLTIALPVPVIVSNFENF 365
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Medaka
Match: ENSORLT00000025729.2 (shaker-related potassium channel tsha2 [Source:NCBI gene;Acc:101167693]) HSP 1 Score: 337.421 bits (864), Expect = 4.412e-109 Identity = 161/377 (42.71%), Postives = 251/377 (66.58%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSKMCIDNKNYNFLSG-------------FFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXX--XFKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RV IN+SGL FET + L + P TLLG P R + FD RNEYFFDR+R +F+ I +YY+ G +++RP NVP D+F+ E+++++L VI F D+G++ E+ + LP + +++W+LFEYPE+SG A + IVS+L+ ++SI FC+ET+P++ + D + +++G FFI ET+C IWF+ E++ R ++CP+ + K+ N +DIVA++PY+ITL + +++ +G++ S + + + IFKL++HS GLQ+L T QAS+ LG+ + + + ++LFSS +Y+ E D S +SIPDAFWW V++M TVGYGDM P ++ G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 36 ERVVINISGLRFETQLKTLAQFPATLLGDPRKRMRFFDPLRNEYFFDRNRPSFDAIVYYYQSGGRLRRPVNVPVDIFMEEIKFYELGEEVIENFKEDEGFIKEEERPLPEHEFQRQVWLLFEYPESSGAARGIAIVSVLVILISIVIFCLETLPEFREDARDLEAQPYVNGTASADRANPFTDPFFIVETLCIIWFSFELLVRFLACPSKPAFFKNIMNTIDIVAIMPYFITLG-LELAEHQGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAETDDPHSGFSSIPDAFWWAVVSMTTVGYGDMCPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 411
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Medaka
Match: ENSORLT00000004658.2 (pep primary_assembly:ASM223467v1:6:13425755:13435070:-1 gene:ENSORLG00000003738.2 transcript:ENSORLT00000004658.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 336.65 bits (862), Expect = 5.322e-109 Identity = 162/381 (42.52%), Postives = 253/381 (66.40%), Query Frame = 1 Query: 475 AEGHSKSRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSKMCIDNKNYN-----------FLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXX--XFKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 A+ R+ IN+SGL FET + L R PTTLLG P R + +D RNEYFFDR+R +F+ I +YY+ G +++RP +VP D+FL E+++++LE VI F D+G E+ + LPSN +++W+LFEYPE+SG A + IVS+++ ++SI FC+ET+P++ + + N+ F FF+ ET+C +WF+ E + R +SCP+ + K+ N++D+VA+ PY+ITL M +++ ++ S + + + IFKL++HS GLQ+L T +ASL LG+ + +++ ++LFSS++Y+ EV+ +S+ +SIPDAFWW V+TM TVGYGDM P ++ G+ VGS CA++GVLT+A+ VP+I NFN F Sbjct: 27 ADQECSERLVINISGLRFETQLKTLSRFPTTLLGDPRKRIRFYDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVSVPVDIFLEELKFYELEEEVIELFKDDEGLPREEERPLPSNEFQRQVWLLFEYPESSGPARMIAIVSVMVILISIVIFCLETLPEFKDVPPEPDNHANGSAHGKEPSPFTDPFFMVETLCIVWFSFEFMMRFLSCPSKPVFFKNIMNLIDVVAIAPYFITLG-MDLAEHQGSSQQAASLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASLRELGLLIFFLIIGVVLFSSSVYFAEVEDPNSEFSSIPDAFWWAVVTMTTVGYGDMCPTTIGGKFVGSLCAIAGVLTIALPVPVIVSNFNYF 406
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Medaka
Match: ENSORLT00000010657.2 (potassium voltage-gated channel subfamily A member 2 [Source:NCBI gene;Acc:101157775]) HSP 1 Score: 337.035 bits (863), Expect = 1.289e-108 Identity = 166/414 (40.10%), Postives = 259/414 (62.56%), Query Frame = 1 Query: 400 LSSTSSTPGEIAPFNDVNKFNRYSVAEGHSK-SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKY---------------SKMCIDNKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXX-----FKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 ++ +S P + A + ++Y H RV IN+SGL FET + L + P TLLG P R ++FD RNEYFFDRHR +F+ I +YY+ G +++RP NV D+F E+ +++L + F D+G++ E+ + LP N +++W+LFEYPE+SG A + I+S+++ ++SI +FC+ET+P + S D+ Y F FFI ET+C IWF+ E + R +CP+ + + N++DIVA+IPY+ITL L ++ DG+ G ++++ + + + FKL++HS GLQ+L T +AS+ LG+ + + + ++LFSS +Y+ E D K S +SIP+AFWW V++M TVGYGDMVP ++ G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 1 MTVATSDPMDEAAAHPCQPNDQYGPETDHDCCERVVINISGLRFETQLKTLSQFPETLLGDPKKRMRYFDPLRNEYFFDRHRPSFDAILYYYQSGGRLRRPVNVTLDIFSEEIRFYELGEEAMEIFREDEGFIREEERPLPENEFQRQVWLLFEYPESSGPARIIAIISVMVILISIVSFCLETLPVFRNEEDPYSSYQVMSNSTTTFDSSTY-FTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFGNIMNIIDIVAIIPYFITLGTEL-AERPEDGQSGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADEKQSQFSSIPEAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 412
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Medaka
Match: kcna1b (potassium voltage-gated channel subfamily A member 1-like [Source:NCBI gene;Acc:101167438]) HSP 1 Score: 333.183 bits (853), Expect = 4.597e-107 Identity = 166/380 (43.68%), Postives = 249/380 (65.53%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSKMCIDN-----------KNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSD-NCIDGKKGGSSXXXXXXXXXXXX------FKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RV IN+SGL FET + L + P TLLG+P R ++FD RNEYFFDR+R +F+ I +YY+ G +++RP NVP D+F E+++++L + F D+G++ E+ + LP ++IW+LFE+PE+SG A + IVS+++ ++SI FC+ET+P+ + D K F FF+ ET+C IWF+ E+I R +CP+ + K+ N +DIVA+IPY+ITL L D + +GK GG L ++R+IR+ FKL++HS GLQ+L T +AS+ LG+ + + + ++LFSS +Y+ E + K+S SIPDAFWW V++M TVGYGDM P ++ G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 36 ERVVINISGLRFETQLKTLAQFPETLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFYELGAEAMEKFREDEGFIREEERPLPEKEFQRQIWLLFEHPESSGPARGIAIVSVMVILISIVIFCLETLPELKEDPNDRIQVVGNGTIYYKANFFTDPFFVVETLCIIWFSFELIVRFFACPSKAAFFKNMMNSIDIVAIIPYFITLGTELADDQDNKEGKAGGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEDKESFFTSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 415
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Medaka
Match: kcna2a (potassium voltage-gated channel, shaker-related subfamily, member 2a [Source:ZFIN;Acc:ZDB-GENE-131113-1]) HSP 1 Score: 330.872 bits (847), Expect = 1.413e-106 Identity = 161/386 (41.71%), Postives = 247/386 (63.99%), Query Frame = 1 Query: 493 SRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIP-----------KYSKMCIDNKNYNFLS--------GFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXX-----FKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 RV IN+SGL FET + L + P TLLG P R ++FD RNEYFFDR+R +F+ I +YY+ G +++RP NV D+F E+ +++L I F D+G++ E+ + LP N +++W+LFEYPE+SG A + I+S+++ ++SI +FC+ET+P ++K+ N +S FFI ET+C IWF+ E + R +CP+ + + N++DIVA+IPY+ITL L +D DG+ G ++++ + + + FKL++HS GLQ+L T +AS+ LG+ + + + ++LFSS +Y+ E D +S SIPDAFWW V++M TVGYGDMVP ++ G+IVGS CA++GVLT+A+ VP+I NFN F Sbjct: 29 ERVVINISGLRFETQLKTLSQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVTLDIFSEEIRFYELGEEAIEMFREDEGFIKEEERPLPDNEFQRQVWLLFEYPESSGPARIIAIISVMVILISIVSFCLETLPIFRNDEDDMHKSHAKVFSPETNTTIISYTSTYFTDPFFILETLCIIWFSFEFLVRFFACPSKAGFFGNIMNIIDIVAIIPYFITLGTEL-ADRPEDGQPGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADEPESQFESIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 413
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Planmine SMEST
Match: SMESG000006565.1 (SMESG000006565.1) HSP 1 Score: 823.157 bits (2125), Expect = 0.000e+0 Identity = 409/410 (99.76%), Postives = 409/410 (99.76%), Query Frame = 1 Query: 352 MSNTFNFTHNYRYREFLSSTSSTPGEIAPFNDVNKFNRYSVAEGHSKSRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIKLPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSKMCIDNKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXXFKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKFQS 1581 MSNTFNFTHNYRYREFLSSTSSTPGEIAPFNDVNKFNRYSVAEGHSKSRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIKLPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSKMCIDNKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSLAILRVIRLIRIFKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF S Sbjct: 1 MSNTFNFTHNYRYREFLSSTSSTPGEIAPFNDVNKFNRYSVAEGHSKSRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIKLPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSKMCIDNKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSLAILRVIRLIRIFKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKFYS 410
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Planmine SMEST
Match: SMESG000013562.1 (SMESG000013562.1) HSP 1 Score: 436.802 bits (1122), Expect = 6.912e-148 Identity = 212/365 (58.08%), Postives = 286/365 (78.36%), Query Frame = 1 Query: 490 KSRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIKLPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSKM-CIDNKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXXFKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKFQS 1581 K +V IN+SGL FETW L+ HPTTLLG P+ R ++D +R EYFFDR+R AFE IF+YY+ G KIKRP NVP+++FL+E++++++E +VI+ + D+G+ E I+LP+N + + IW+LFE+PETS A+ V ++S+ T++SI FC+ET P ++K C+ NFL FFI ET+CT WFTIE+ R +SCP+ +++KD KN++D+ A+IPYY+TL N+L + +C DG K +SLA LRVIRLIR+FKLTKHS GLQVL+LTF+AS+ GLG+FL+A+ VS++LFSSTIYY EV DS I SIPDAFWW +ITMCTVGYGD VP+ ++G++VGS CAVSGVLTLA+ VPII+ENFNKF S Sbjct: 99 KEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIELPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKSHCVSGAAPNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDC-DGAKKSASLAFLRVIRLIRVFKLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYS 462
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Planmine SMEST
Match: SMESG000014198.1 (SMESG000014198.1) HSP 1 Score: 405.216 bits (1040), Expect = 2.170e-136 Identity = 201/371 (54.18%), Postives = 271/371 (73.05%), Query Frame = 1 Query: 472 VAEGHSKSRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIKLPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSKM-CIDNKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXXFKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKFQS 1581 + G +INVSG+ FE L HPTTLLG K +FD R NEYFFDRHR FE IF YY+Y +KRP +VP+D+FL E+++F++E V+ + ++G+V E LP QK+W+LFEYPETS AY +G++S++ T++SI FC+ET+P + + C+D NFL FF+ ET CT WF++E I RLV CP+ ++KD KN +DI+A++PYY+TL N+L+S +C G K +SLA LRVI+LIRIFKLTKHS+GLQVL+ TF+AS+ LG+F++A+ + ++LFSS +YY+E +DSDI SIP AFWW +ITMCTVGYGD VP+ +G+IVGSFCAV+GVLTLA+ VPII+ENFNKF S Sbjct: 37 LVNGPGAQTTKINVSGMKFEIPTYKLKYHPTTLLGDSHKCKSYFDKRFNEYFFDRHRPTFEAIFVYYQYSCDLKRPFDVPDDIFLEELKFFQIEKEVVMKYKLEEGHVEETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCVDGSAPNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTLVNVLYSFSC-SGAKNSASLAFLRVIKLIRIFKLTKHSSGLQVLLKTFRASIESLGLFVVALSMLVILFSSALYYVENTYEDSDIKSIPHAFWWAIITMCTVGYGDAVPQHFLGKIVGSFCAVAGVLTLAIPVPIITENFNKFYS 406
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Planmine SMEST
Match: SMESG000014206.1 (SMESG000014206.1) HSP 1 Score: 401.364 bits (1030), Expect = 6.921e-135 Identity = 200/371 (53.91%), Postives = 270/371 (72.78%), Query Frame = 1 Query: 472 VAEGHSKSRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIKLPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSKM-CIDNKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXXXXFKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKFQS 1581 + G +INVSG+ FE L HPTTLLG K +FD R NEYFFDRHR FE IF YY+Y +KRP +V +D+FL E+++F++E V+ + ++G+V E LP QK+W+LFEYPETS AY +G++S++ T++SI FC+ET+P + + C+D NFL FF+ ET CT WF++E I RLV CP+ ++KD KN +DI+A++PYY+TL N+L+S +C G K +SLA LRVI+LIRIFKLTKHS+GLQVL+ TF+AS+ LG+F++A+ + ++LFSS +YY+E +DSDI SIP AFWW +ITMCTVGYGD VP+ +G+IVGSFCAV+GVLTLA+ VPII+ENFNKF S Sbjct: 37 LVNGPGAQTTKINVSGMKFEIPTYKLKYHPTTLLGDSHKCKSYFDKRFNEYFFDRHRPTFEAIFVYYQYSCDLKRPFDVLDDIFLEELKFFQIEKEVVMKYKLEEGHVEETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCVDGSAPNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTLVNVLYSFSC-SGAKNSASLAFLRVIKLIRIFKLTKHSSGLQVLLKTFRASIESLGLFVVALSMLVILFSSALYYVENTYEDSDIKSIPHAFWWAIITMCTVGYGDAVPQHFLGKIVGSFCAVAGVLTLAIPVPIITENFNKFYS 406
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Planmine SMEST
Match: SMESG000020672.1 (SMESG000020672.1) HSP 1 Score: 347.821 bits (891), Expect = 1.623e-112 Identity = 179/417 (42.93%), Postives = 255/417 (61.15%), Query Frame = 1 Query: 379 NYRYREFLSSTSSTPGEIAPFNDVNKFNRYSVAEGHSKSRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIK-LPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSKMCIDNKNY----------------NFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSXXXXXXXXXX-XXFKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKF 1575 +YR F S P E P++ V + Y + RV IN+SGL FET + L + P TLLG+ R Q+FD RNEYFFDR+R +F+ I +YY+ G +++RP NVP DVF E+++++L I + D+GY+ E IK LP NP +K+W+LFEYPE+S A V I S+ + I+SI FCIET+P + I N + F FFI ET+C IWFT E++ R S P + K N++DIVA+IPY+ITL ++ D+ + ++ + + + RIFKL++HS GLQ+L T +AS+ LG+ + +L+S++LFSS +Y+ E D S SIPDAFWW V+TM TVGYGDM P ++ G++VGS CA++GVLT+A+ VP+I NFN F Sbjct: 29 DYRSHTFNQSMPKYPDEETPYDKVGENAEYDI------ERVTINISGLRFETQLKTLGQFPNTLLGNALKRNQYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPIDVFCEEIKFYELGEEAIEKYREDEGYIKEDIKILPENPFQRKVWLLFEYPESSMGARCVAICSVFVIILSIVIFCIETLPHFKHYRIVNSTFAGTNQSAYKIEEDDIPQFSEPFFIIETVCIIWFTFELLVRFSSSPEKLTFFKTIMNLIDIVAIIPYFITLGTVIADDSRSQNQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASVRELGLLVFFLLISVILFSSAVYFAEADADKSYFRSIPDAFWWAVVTMTTVGYGDMRPVTVWGKLVGSLCAIAGVLTIALPVPVIVSNFNYF 439 The following BLAST results are available for this feature:
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30020664 ID=SMED30020664|Name=Potassium voltage-gated channel subfamily A member 2|organism=Schmidtea mediterranea sexual|type=transcript|length=1892bpback to top protein sequence of SMED30020664-orf-1 >SMED30020664-orf-1 ID=SMED30020664-orf-1|Name=SMED30020664-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=447bp MSNTFNFTHNYRYREFLSSTSSTPGEIAPFNDVNKFNRYSVAEGHSKSRVback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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