PKD1L-2
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30020654 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 11
Homology
BLAST of PKD1L-2 vs. Ensembl Human
Match: PKD1L2 (polycystin 1 like 2 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:21715]) HSP 1 Score: 149.443 bits (376), Expect = 2.977e-35 Identity = 100/338 (29.59%), Postives = 171/338 (50.59%), Query Frame = 2 Query: 1217 WNFNMEVWQDFSASVDDTSDISNINFKSNFLGTFSAKIFIAPNMIDFKNVFANFASLLANSXXXXXXXXXXXXXXXXXXXXMW--RKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVL-LEIKRDEK-FQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTGIISVLITYPCIFIASEIF 2218 W+ E W D V + + N L F + + N I+ FA+ N VV V L + L++ +W RKD ++ ++ L DNDP +Y Y+++V+TG R A TSS + + L G G + D +FE G V F+++T PLG+L +LR+WH++SG +PSW + ++++ D+ ++ + F+C +WLS + D ++V + ++D K F +LF +G D HI I + S +TRVQ+V+ ++ M+++ MF+G + A K+D G I TW + G+ S ++ +P + +IF Sbjct: 600 WDEVQETWDDSGCQVGPRTSPYQTHCLCNHLTFFGSTFLVMSNAINIHQTAELFATFEDNPVVVTTVGCLCVVYVLVV---IWARRKDAQDQAKVKVTVLEDNDPFAQYHYLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADP-DTPVFERGAVDAFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDRKWYFLCNSWLSINVGDCVLDKVFPVATEQDRKQFSHLFFMKTSAGFQDGHIWYSIFSRCARSSFTRVQRVSCCFSLLLCTMLTSIMFWGVPKD---PAEQKMDLGKIEFTWQEVMIGLESSILMFPINLLIVQIF 930 HSP 2 Score: 54.299 bits (129), Expect = 2.828e-6 Identity = 71/278 (25.54%), Postives = 115/278 (41.37%), Query Frame = 2 Query: 2288 LPKGFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPIILLIIFVLAKKLLGAVSTDQEANI----DEFVKDDLKKVLGANLN-------PPDQEKLEKIKKDKASGQRLSRVVGXXXXXXXXXXXXXXXXXXXRSQVTFDQTKMIRSRFIK--SNVQTYMDFYDWAQGILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISALVSKVYGNVPCNENYNLLSEDTRSFSVKW--TPLANSSV 3076 LP I VGW L+ + FFT LY L +G S +WL + V +F++ P+ +L +L V D+E + + D + A N PP +EK+K Q+ ++ + L Y+ L +L +AY R + + ++ F + S V + +F+ WA L N G I + G +IRQ+RV+ ++C + A + Y N C Y+L +ED + W T L+N S Sbjct: 1132 LPWWCILVGWLLVAATSGVAAFFTMLYGLHYGRASSLRWLISMAVSFVESMFVTQPLKVLGFAAFFALVLKRVD-DEEDTVAPLPGHLLGPDPYALFRARRNSSRDVYQPPLTAAIEKMKTTHLKEQKAFALIREILAYLGFLWMLLLVAYGQRDPSAYHLNRHLQHSFTRGFSGVLGFREFFKWANTTLVS----------NLYGHPPGFITDGNSKLVGSAQIRQVRVQESSCPL-AQQPQAYLNG-CRAPYSLDAEDMADYGEGWNATTLSNGST 1396
BLAST of PKD1L-2 vs. Ensembl Human
Match: PKD1L2 (polycystin 1 like 2 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:21715]) HSP 1 Score: 149.058 bits (375), Expect = 3.984e-35 Identity = 100/338 (29.59%), Postives = 171/338 (50.59%), Query Frame = 2 Query: 1217 WNFNMEVWQDFSASVDDTSDISNINFKSNFLGTFSAKIFIAPNMIDFKNVFANFASLLANSXXXXXXXXXXXXXXXXXXXXMW--RKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVL-LEIKRDEK-FQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTGIISVLITYPCIFIASEIF 2218 W+ E W D V + + N L F + + N I+ FA+ N VV V L + L++ +W RKD ++ ++ L DNDP +Y Y+++V+TG R A TSS + + L G G + D +FE G V F+++T PLG+L +LR+WH++SG +PSW + ++++ D+ ++ + F+C +WLS + D ++V + ++D K F +LF +G D HI I + S +TRVQ+V+ ++ M+++ MF+G + A K+D G I TW + G+ S ++ +P + +IF Sbjct: 1285 WDEVQETWDDSGCQVGPRTSPYQTHCLCNHLTFFGSTFLVMSNAINIHQTAELFATFEDNPVVVTTVGCLCVVYVLVV---IWARRKDAQDQAKVKVTVLEDNDPFAQYHYLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADP-DTPVFERGAVDAFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDRKWYFLCNSWLSINVGDCVLDKVFPVATEQDRKQFSHLFFMKTSAGFQDGHIWYSIFSRCARSSFTRVQRVSCCFSLLLCTMLTSIMFWGVPKD---PAEQKMDLGKIEFTWQEVMIGLESSILMFPINLLIVQIF 1615 HSP 2 Score: 54.299 bits (129), Expect = 2.360e-6 Identity = 71/278 (25.54%), Postives = 115/278 (41.37%), Query Frame = 2 Query: 2288 LPKGFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPIILLIIFVLAKKLLGAVSTDQEANI----DEFVKDDLKKVLGANLN-------PPDQEKLEKIKKDKASGQRLSRVVGXXXXXXXXXXXXXXXXXXXRSQVTFDQTKMIRSRFIK--SNVQTYMDFYDWAQGILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISALVSKVYGNVPCNENYNLLSEDTRSFSVKW--TPLANSSV 3076 LP I VGW L+ + FFT LY L +G S +WL + V +F++ P+ +L +L V D+E + + D + A N PP +EK+K Q+ ++ + L Y+ L +L +AY R + + ++ F + S V + +F+ WA L N G I + G +IRQ+RV+ ++C + A + Y N C Y+L +ED + W T L+N S Sbjct: 1817 LPWWCILVGWLLVAATSGVAAFFTMLYGLHYGRASSLRWLISMAVSFVESMFVTQPLKVLGFAAFFALVLKRVD-DEEDTVAPLPGHLLGPDPYALFRARRNSSRDVYQPPLTAAIEKMKTTHLKEQKAFALIREILAYLGFLWMLLLVAYGQRDPSAYHLNRHLQHSFTRGFSGVLGFREFFKWANTTLVS----------NLYGHPPGFITDGNSKLVGSAQIRQVRVQESSCPL-AQQPQAYLNG-CRAPYSLDAEDMADYGEGWNATTLSNGST 2081
BLAST of PKD1L-2 vs. Ensembl Human
Match: PKD1L3 (polycystin 1 like 3, transient receptor potential channel interacting [Source:HGNC Symbol;Acc:HGNC:21716]) HSP 1 Score: 135.961 bits (341), Expect = 3.093e-31 Identity = 86/338 (25.44%), Postives = 167/338 (49.41%), Query Frame = 2 Query: 1217 WNFNMEVWQDFSASVDDTSDISNINFKSNFLGTFSAKIFIAPNMIDFKNVFANFASLLANSXXXXXXXXXXXXXXXXXXXXMW--RKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVLLEIKRDE--KFQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTGIISVLITYPCIFIASEIF 2218 W + + W V S I N L F++ F+ P ++ ++ F + N V ++ L+ + + +W +KD+ + ++ L DNDP ++ Y+I V+TG R+A T++ + I L G G S + D + +FE G + F++TT + LG+L +LR+WH++SG+ PSW + ++++ D+ + + F+C WL+ D +RV + + + E F++LF M V ++ I + +TRVQ+++ +T+ MV N MF+ K N+ + + ++ ++ W + I + +I +P + +F Sbjct: 638 WEIHNQTWSSAGCQVGPQSTILRTQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITV---VWARKKDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKT-VFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQFTRVQRLSCCMTLLLCNMVINVMFW-KINSTTAKRDEQMR--PFAVAWSELLVSIHTAVILFPINLVIGRLF 968
BLAST of PKD1L-2 vs. Ensembl Human
Match: PKD2L1 (polycystin 2 like 1, transient receptor potential cation channel [Source:HGNC Symbol;Acc:HGNC:9011]) HSP 1 Score: 114.39 bits (285), Expect = 7.301e-25 Identity = 104/451 (23.06%), Postives = 201/451 (44.57%), Query Frame = 2 Query: 2774 VQTYMDFYDWAQG-ILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISALVSKVYGNVPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTYAETIDE 4123 + + DF+D+AQG +L+ Y WYNN + G + + + + G R+RQ++V+ ++C + +E++ ED S ++P + F N A+ Y + GG+ G Y GGGY L ++ +A +R LQ WLD+ TR +F + +VYN N NLF ++++ E P +GG + + +R+ +L Y+ ++ ++++ + + + EI ++ + Y SS WN+++L+ I LS+ + R + + L Y F+ W + ++ F + I++ KY+ FNK ++ + T+ R + MF A+ +G +LF F+ + + F + + Y + A + + + ++F+ I+NDTY+E +E Sbjct: 151 ISSMADFWDFAQGPLLDSLYWTKWYNNQS-LGHGSHSFIYYENMLLGVPRLRQLKVRNDSCVV-------------HEDFR---EDILSCYDVYSPDKEEQLPFGPFNGT------------AWTYHSQDELGGFSHWGRLTSYSGGGYYLDLPGSRQGSAEALRALQEGLWLDRGTRVVFIDFSVYNANINLFCVLRLVVEFPATGG-AIPSWQIRTVKLIRYVSNWDFFIVGCEVIFCVFIFYYVVEEILELHIHRLRYLSSIWNILDLVVILLSIVAVGFHIFRTLEVNRLMGKLLQQPNTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAVMFFIVFFAYAQLGYLLFGTQVENFSTFIKCIFTQFRIILGDFDYNAIDNANRILGPAYFVTYVFFVFFVLL-NMFLAIINDTYSEVKEE 570
BLAST of PKD1L-2 vs. Ensembl Human
Match: PKDREJ (polycystin family receptor for egg jelly [Source:HGNC Symbol;Acc:HGNC:9015]) HSP 1 Score: 105.531 bits (262), Expect = 7.189e-22 Identity = 79/320 (24.69%), Postives = 157/320 (49.06%), Query Frame = 2 Query: 1268 TSDISNINFKSNFLGTFSAKIFIAPNMIDFK-NVFANFASLLANSXXXXXXXXXXXXXXXXXXXXMWRKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVLLEIKRDEKF--QNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTGIISVLITYPCIFIASEIF 2218 T ++ I+ ++++ AK+ + PN +D + N+ SL N + V+ +I + L ++R + + + L DNDP Y++++ TGS +GT +++F+ L G +S ++ + L+ G++ F++TT S LGD+ ++R+WHN+ G PSW L ++ +E++ + +++F+C+ WLS D +R DE+ ++ F S + H+ I + + R+Q+++ + M ++ N MFF + ++ + + I GI SVLIT P + + +F Sbjct: 1146 TIGLTGIHLHTHYV---MAKVIVIPNPVDLRLNIIK---SLHQNPVTLFTVLFIILLYVGLAFWALYRDEMDQHLRGHVIVLPDNDPYDNLCYLVTIFTGSRWGSGTRANVFVQLRGTVSTSDVHCLSHPHFTTLYR-GSINTFLLTTKSDLGDIHSIRVWHNNEGRSPSWYLSRIKVENLFSRHIWLFICQKWLS---VDTTLDRTFHVTHPDERLTRKDFFFIDVSSNLRKNHMWFSIFASVVAKTFNRLQRLSCCLAMLLSSLLCNIMFFNLNRQEQTESRERKYMRSMMI-------GIESVLITIPVQLLITFLF 1448 HSP 2 Score: 93.2041 bits (230), Expect = 4.267e-18 Identity = 152/654 (23.24%), Postives = 271/654 (41.44%), Query Frame = 2 Query: 2258 QEAKMKKMFLLPKGFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDP--IILLIIFVLAK------------------KLLGAVSTDQEANIDEFVKDDLKKVLGANLNPPDQEKLEKIKKDKASGQRLSRV-VGXXXXXXXXXXXXXXXXXXXRSQVTFDQTKMIRSRFIK--SNVQTYMDFYDWAQGILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVK--RNTCTISA--LVSKVYGNVPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSP--TQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRL--YDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITS---VFICILNDTYAETI 4117 Q+ K K +LP ++V W L+F S FF Y L +G +KS +WL F V L P IILL F K +L G +E + + D + ++ G + P E +I K K +R + + + LT+ + L LL L R F + IR RF + V D Y W LN + +N++N T ++ I G +RQ+R K C + + + + + C+ Y + EDT+++S W + ++ D + N P TQ + ++ + SGGY + + ++L +K+ LQ +NWLD+ T A+ E T +N + NLF +I V+FE G + + S+ L +D I L + +++ L V++ E + +++ Y S +NL+ + +I+ + + I N ++ F + I++G F++I++ L+Y F + + Q I A + + F+ + ++ G ++F + ++NL+ ST ++F V+ AF + + N L V F++S V IC+L + + I Sbjct: 1562 QQLKKKPRIVLPWWCVYVAWFLVFATSSISSFFIVFYGLTYGYDKSIEWLFASFCSFCQSVLLVQPSKIILLSGFRTNKPKYCKNLSWSTKYKYTEIRLDGMRMHPEEM---QRIHDQIVRIRGTRMYQPLTEDEIRIFKRKKRIKRRALLFLSYILTHFIFLALLLILIVLLRHTDCFYYNQFIRDRFSMDLATVTKLEDIYRW----LNSVLLPLLHNDLNPTFLPESSSKIL-----GLPLMRQVRAKSSEKMCLPAEKFVQNSIRREIHCHPKYGIDPEDTKNYSGFWNEVDKQAI---DESTNGFTYKPQGTQWLYYSYGLLHTYGSGGY---ALYFFPEQQRFNSTLRLKE---------LQESNWLDEKTWAVVLELTTFNPDINLFCSISVIFEVSQLGVVNT-SISLHSFSLADFDRKASAEIYLYVAILIFFLAYVVD---EGCIIMQERASYVRSVYNLLNFALKCIFTVLIVLFLRKHFLATGIIRFYLSNPEDFIPFHAVSQVDHIMRIILGFLLFLTILKTLRYSRFFYDVRLAQRAIQAALPGICHMAFVVSVYFFVYMAFGYLVFGQHEWNYSNLIHSTQTVFSYCVS------------AFQNTEFSNN-RILGVLFLSSFMLVMICVLINLFQAVI 2171
BLAST of PKD1L-2 vs. Ensembl Celegans
Match: pkd-2 (Polycystin-2 [Source:UniProtKB/Swiss-Prot;Acc:Q9U1S7]) HSP 1 Score: 97.4413 bits (241), Expect = 4.409e-20 Identity = 114/462 (24.68%), Postives = 203/462 (43.94%), Query Frame = 2 Query: 2780 TYMD-FYDWAQGILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISALVSKVYGNVPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASL---GMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTYAETIDENLFDYDKEMV 4153 T MD +DW +L P +++ + + D I + L P RIR ++V ++CT+ + C NY ED T + + SV +AF+Y GT YGGGG++ L G + Q+A I L+AN W+D+ +RAI + +YN N NLF +++LFE P SGG+ P + +Y L Y +++ + ++ ++ I+ E+ + + + Y + WNLV+++ + S++ II + R +N + + N FD TS + + FV+ ++V K++ NK +S + T+ R+ + MF F AF G + F ++NL S +L + + + + E+ F ++ + F + ++F+ I+ND+Y E E D E + Sbjct: 126 TSMDNIWDWLSQVL---IPGIYWTETSNSTDNENMIYYENRLLGEP-RIRMLKVTNDSCTVMKSFQREIKE--CFANYEEKLEDK-------TMVGDGSV-------------------DAFIYATAKELENLKTVGTIASYGGGGFVQRLPVAGSTEAQSA--IATLKANRWIDRGSRAIIVDFALYNANINLFCVVKLLFELPASGGVITTP-KLMTYDLLTYQTSGGTRMMIFEGIFCGFILYFIFEELFAIGRHRLHYLTQFWNLVDVVLLGFSVATIILSVNRTKTGVNRVNSVIENGLTNAPFDDVTSSENSYLNIKACVVFVAWVKVFKFISVNKTMSQLSSTLTRSAKDIGGFAVMFAVFFFAFAQFGYLCFGTQIADYSNLYNSAFALLRLILGDFNFSAL-ESCNRFFGPAFFIAYVFFVSFILLNMFLAIINDSYVEVKAELARKKDGEGI 551
BLAST of PKD1L-2 vs. Ensembl Celegans
Match: lov-1 (Location of vulva defective 1 [Source:UniProtKB/Swiss-Prot;Acc:Q09624]) HSP 1 Score: 88.5817 bits (218), Expect = 4.175e-17 Identity = 56/149 (37.58%), Postives = 78/149 (52.35%), Query Frame = 2 Query: 1475 RRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSS---GHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGI--KPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVL-LEIKR 1903 R+++ R L DN+P Y YVI+V TG A T S I NL G G R DG + F GT FVMTT PLG+L +R+W + +G+ + SW +++++D+QT +Y F WL DG TER+ +E KR Sbjct: 2268 RKDASRGRLRFLKDNEPHDGYMYVIAVETGYRMFATTDSTICFNLSGNEGDQIFRSFRSEEDGNWEFPFSWGTTDRFVMTTAFPLGELEYMRLWLDDAGLDHRESWYCNRIIVKDLQTQDIYYFPFNNWLGTKNGDGETERLARVEYKR 2416 HSP 2 Score: 72.0182 bits (175), Expect = 4.552e-12 Identity = 92/400 (23.00%), Postives = 165/400 (41.25%), Query Frame = 2 Query: 2771 NVQTYMDFYDWAQGILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNT-CTISALVSKVYGNV-PCNENYNLLSED-TRSFSVKWTPLA--NSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIK--------------------KVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKG-FYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTV 3892 ++Q DF+DWA+ L + WY+ N + + G IRQ+R K++ CT + + G + C E +E+ T WT L N + + ++ + + T+TV + LY + GGY S+ Q + + L + W+D TRA+ E + YN N F+ +Q+L E P S G+ + V S RL + V+ ++LY VL +EI K+ Q S WN ++L+ L+++ ++ +R T A+ N N G Y++ + +W + + F + ++++ + FN+ I ++ T+ A + S G F+ F + F +V Sbjct: 2726 SIQHADDFWDWARESLATALLASWYDG-NPAYGMRAYMNDKVSRSMGIGTIRQVRTKKSAECT---MFKQFQGYINDCGEELTSKNEEKTLYMQAGWTELESENGTDASDEYTYKTSEELSTETV-SGLLYSYS--GGGYTI--------------SMSGTQAEIITLFNKLDSERWIDDHTRAVIIEFSAYNAQINYFSVVQLLVEIPKS-GIYLPNSWVESVRLIKSEGSDGTVVKYYEMLYIFFSVLIFVKEIVFYLYGRYKVITTMKPTRNPFKIVYQLALGNFSPWNFMDLIVGALAVASVLAYTIRQRTTNRAMEDFNANNGNSYINLTEQRNWEIVFSYCLAGAVFFTSCKMIRILRFNRRIGVLAATLDNALGAIVSFGIAFLFFSMTFNSV 3103
BLAST of PKD1L-2 vs. Ensembl Fly
Match: Pkd2 (gene:FBgn0041195 transcript:FBtr0080365) HSP 1 Score: 94.3597 bits (233), Expect = 5.064e-19 Identity = 92/404 (22.77%), Postives = 190/404 (47.03%), Query Frame = 2 Query: 2909 GPFRIRQIRVKRNTCTISALVSKVYGNVPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYG-VRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQK-KEYFSSNWNLVEXXXXX---XXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTY 4105 GP R+RQIRV++ +C ++ + + C Y+ +ED + K +P + +D + +P TV+ + +GGY +L +++ II +L+ +WLD+ +R E ++N NT++F +I+++ E P +GG+ P +++ ++Y + +++ ++ I + + V+ EI ++ K K YF S N+++ + L+L I + ++M ++ A +V Y S D W +M I +F+ I++ K++ FNK + T+ R L+ MF +A+ +G +LF + F N +TS +++ + + +Y ++ E +Y+ + L F + ++F+ I+ +TY Sbjct: 436 GPPRLRQIRVRKESCYVNDAFIRYFNT--CYAAYSSGAEDRKPMH-KGSPFR----TMHDLDS-----TPIWTVLAFYR------TGGY--------------TVNLDYDKDRNVKIINDLKDIHWLDRGSRLCLVEFNLFNENTDIFQSIKLIAEIPPTGGV--IPQAHLQTVKMYSFFTDRSMLMTVIYIFWYIMVIYYTIYEITEIRKSGIKIYFCSMLNILDCAILLGCYLALVYNIWHSFKVM-SLTARAHSDVT---YQSLDVLCFWNIIYVDMMAILAFLVWIKIFKFISFNKTLVQFTTTLKRCSKDLAGFSLMFGIVFLAYAQLGLLLFGTKHPDFRNFITSILTMIRMILGDFQY-NLIEQANRVLGPIYFLTYILLVFFILLNMFLAIIMETY 800
BLAST of PKD1L-2 vs. Ensembl Fly
Match: brv2 (gene:FBgn0036712 transcript:FBtr0331846) HSP 1 Score: 53.9138 bits (128), Expect = 1.440e-6 Identity = 59/243 (24.28%), Postives = 110/243 (45.27%), Query Frame = 2 Query: 3260 IRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLY---DYLPGNMIVL----LLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNV----NKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVS 3955 I L+ +WLDK T A+F + T+YN + NLFT I + E NS P+G++ R++ + GN+ LL+ +Y + V+L K+ + W +V+ + + + + T + IM I +L + KG Y+ F + + I+ G ++ +R+ K + F T+ A+ ++SLG + + L+A + N V F++++ S V+ Sbjct: 289 IEYLRDYSWLDKNTSALFIDLTMYNADANLFTLITLRVE--NS------PFGIQLPRVHVDSVSMLGNVETRSNSELLILFVYTVLVILFARGVFTKIWHHPAAAHEA-WTMVD---LAIYILNVFLTVLAIMRDIETDALLQIIETATKGQYLDFQRPLRLHQMLFIVKGFLVCITTLRLWKVLQFASVFQHFTQTLFSAWRAVASLGVIILVVLMAIGITLAVPNGNNAVVFSHMVQSVVT 519
BLAST of PKD1L-2 vs. Ensembl Fly
Match: brv2 (gene:FBgn0036712 transcript:FBtr0075242) HSP 1 Score: 53.1434 bits (126), Expect = 1.997e-6 Identity = 59/243 (24.28%), Postives = 110/243 (45.27%), Query Frame = 2 Query: 3260 IRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLY---DYLPGNMIVL----LLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNV----NKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVS 3955 I L+ +WLDK T A+F + T+YN + NLFT I + E NS P+G++ R++ + GN+ LL+ +Y + V+L K+ + W +V+ + + + + T + IM I +L + KG Y+ F + + I+ G ++ +R+ K + F T+ A+ ++SLG + + L+A + N V F++++ S V+ Sbjct: 311 IEYLRDYSWLDKNTSALFIDLTMYNADANLFTLITLRVE--NS------PFGIQLPRVHVDSVSMLGNVETRSNSELLILFVYTVLVILFARGVFTKIWHHPAAAHEA-WTMVD---LAIYILNVFLTVLAIMRDIETDALLQIIETATKGQYLDFQRPLRLHQMLFIVKGFLVCITTLRLWKVLQFASVFQHFTQTLFSAWRAVASLGVIILVVLMAIGITLAVPNGNNAVVFSHMVQSVVT 541
BLAST of PKD1L-2 vs. Ensembl Fly
Match: brv3 (gene:FBgn0040333 transcript:FBtr0340092) HSP 1 Score: 51.2174 bits (121), Expect = 9.203e-6 Identity = 67/309 (21.68%), Postives = 142/309 (45.95%), Query Frame = 2 Query: 3257 IIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLY---DYLPGNMIVLLLMQIL----YALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITML-NVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSL----FGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTYAETIDENLFDYDKE 4147 +I L N+WL T A+F + T+YN + NLF+ + E+ GG+ + V S +L D +P ++ LL+ +L +A T+ + ++ E S WN ++L +++ +++ +R + + + + +K ++ F + + + + I +G ++ +R+ + + F + T+ A++ ++S + FLI F + + F L+ S V FG F A VK ++F L Y V + + + + +VF+ ++ND + T+ + + D ++E Sbjct: 311 VIDYLSENHWLTLNTSAVFIDFTLYNVDVNLFSICTLRVEKTPFGGI-VPDVQVDSAKLLENVDQMPYTGLLALLIYVLVFIQFAQTLAVKLWYE--------PHLLKSVWNKLDLFIFMVNVLVVVLVVLRESLVASMMKKVEGASKMEFIDFRRPSRMHQLTTITIGFLICITTLRLWRVLQFASVFKLFTRTLYLAWSAVASTAIAIVIFLIGFCFAVVTINGNYSSNFNKLVKSMVMCMCYSFG-FSAQVKPSELFHGGKWL-GILCYGVLAFVIIVLLINVFVSLINDYF--TVAKTIRDSERE 606
BLAST of PKD1L-2 vs. Ensembl Zebrafish
Match: pkd1l2a (polycystic kidney disease 1 like 2a [Source:ZFIN;Acc:ZDB-GENE-050208-89]) HSP 1 Score: 163.31 bits (412), Expect = 1.281e-39 Identity = 179/680 (26.32%), Postives = 309/680 (45.44%), Query Frame = 2 Query: 2255 DQEAKMKKMFLLPKGFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPIILLIIFVLAKKLLGAVSTDQ--EANIDEFVK--DDLKKVLGANLN-------PPDQEKLEKIKKDKASGQRLSRVVGXXXXXXXXXXXXXXXXXXXRSQVTFDQTKMIRSRFIKSNVQT--YMDFYDWAQGILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISALVSKVYGNVPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPY--GVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTYAETIDENLFDYDKEMVDHVWNIFNEMMTGFKSSMKYTVPDALKKKAIV 4249 ++E K LP F+FVGW L+ S +FT LY L +G E+S WL + V F +F++ P+ +L V +L V D+ + +ID + DD V A + PP +EK++ + Q++ ++ + L YV L +L +AY R + T IR F +T + D + WA N S + Y G I + G RIRQ+RV+R+TC I+ + Y C+ Y+ SED S+S W N RN ++ ++TV+ + YQ P G +Y GGG++ LG Q+ A+ +++ L N WLD TRA+F E TVYN N NLF + ++FE + G+ F Y V++ LY G + ++ + +Y + ++ + + K + +QK YF S WNL+EL I LS S + R ++ I NK +VSF++ + L+ ++ I++ + N + ++ T+ RA+T +S + +A+ N+++ + LL + ++ + + I Y ++ + P + L + ++ F + ++FI ++ + E ++E+V+ + ++ G K K T DA A V Sbjct: 1834 EKEGSRKCQKGLPWWFVFVGWFLVLATSGVSAYFTMLYGLTYGKERSISWLISMVVSFFESLFITQPVKVLGFAVFFALVLKTVDQDEYGDVSIDGTLSNTDDPDAVRIARRDSTCSFYKPPPPTDIEKMRNNMIKEQKVFALIREILIYVGFLWMLLLVAYGQRDPNAYYLTHHIRQSFSTGISETLNHKDIFIWA----NSSLLRNLY------GQYPGFITDGNSKLVGNARIRQVRVRRDTCKIANPMQ--YSVRDCHAPYSWESEDMGSYSPGW-------------NQTRN-VNGSKTVLKPWYYQTQAKLRANPVWGGLALYKGGGFVVDLGPDQKNASRLLQYLFDNTWLDVYTRAVFVEFTVYNANVNLFCIVTLIFE---TTGVGTFQYRSEVQAVHLYQSTGGFHVFVMASEAIYYIFILYYMVVQGKLMKQQKWAYFKSKWNLLELAIIILSWSALSVFVKRTILGNRDIEFYQNNKDMFVSFNETATADAVLGYLIAFLVLLATIKLWHLLRLNPKLHMITSTLQRAWTDISGFIVVMTIMFLAYSIACNLMYGWRLNSYRTLLEAAQTIICLQLGIFNYDEVLDYNPVLGAFLIGSCIIFMT-FVVLNLFISVILVAFNEEQLHPTPSEEEEIVELMLMKVCSLL-GIKCKKKQTNADAPMTTASV 2482 HSP 2 Score: 147.902 bits (372), Expect = 6.437e-35 Identity = 96/308 (31.17%), Postives = 164/308 (53.25%), Query Frame = 2 Query: 1316 FSAKIFIAPNMIDFKNVFANFASLLANSXXXXXXXXXXXXXXXXXXXXMW--RKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVL-----LEIKRDEKFQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTGIISVLITYPCIFIASEIF 2218 F + F+ PN++D FA+ + N VV V +I L++ +W RKD ++++ ++ L DNDP EY Y++S++TG R A TSS + + L G G S +TD + +FE G + F++TT LG+L ++R+WH++SG P+W + K+ ++D++ + + F+C +WLS + ++V +++KR F NLF D HI + + S +TRVQ+V+ ++ M+++ MF+G ++ S +D G I TW Q GI S +I +P + IF Sbjct: 1334 FGSSFFVMPNVVDVSRTAELFATFVNNPVVVCFVGAIILAYLLVV---IWARRKDIQDAVKVKVTVLEDNDPLAEYRYLLSINTGQRRGASTSSQVTVTLQGSEGESEPHHLTDPEKP-VFERGGLDLFLLTTPFSLGELQSIRLWHDNSGYYPAWYVNKVTVQDLENGQKWHFLCNSWLSIDLGECTLDKVFPVATEMDLKR---FSNLFFAKTAKDFRDGHIWFSVISRPPSSNFTRVQRVSCCFSLLLCTMLTSIMFWGIPSDPSEQT---MDLGKIEFTWQQVMIGIQSSIIMFPINLLIVSIF 1631
BLAST of PKD1L-2 vs. Ensembl Zebrafish
Match: pkd1l2a (polycystic kidney disease 1 like 2a [Source:ZFIN;Acc:ZDB-GENE-050208-89]) HSP 1 Score: 156.762 bits (395), Expect = 6.949e-38 Identity = 178/709 (25.11%), Postives = 305/709 (43.02%), Query Frame = 2 Query: 2255 DQEAKMKKMFLLPKGFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPIILL---IIFVLAKKLL-----GAVSTD-----------QEANIDEFVKDDLKKVLGANLN-----------------------PPDQEKLEKIKKDKASGQRLSRVVGXXXXXXXXXXXXXXXXXXXRSQVTFDQTKMIRSRFIKSNVQT--YMDFYDWAQGILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISALVSKVYGNVPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTYAETIDENLFDYDKEMVDHVWNIFNEMMTGFKSSMKYTVPDALKKKAIV 4249 ++E K LP F+FVGW L+ S +FT LY L +G E+S WL + V F +F++ P+ +L + F L K + G VS D + N D L V+ L PP +EK++ + Q++ ++ + L YV L +L +AY R + T IR F +T + D + WA L N G I + G RIRQ+RV+R+TC I+ + Y C+ Y+ SED S+S W N RN ++ ++TV+ + YQ P G +Y GGG++ LG Q+ A+ +++ L N WLD TRA+F E TVYN N NLF + ++FE G + + V++ LY G + ++ + +Y + ++ + + K + +QK YF S WNL+EL I LS S + R ++ I NK +VSF++ + L+ ++ I++ + N + ++ T+ RA+T +S + +A+ N+++ + LL + ++ + + I Y ++ + P + L + ++ F + ++FI ++ + E ++E+V+ + ++ G K K T DA A V Sbjct: 443 EKEGSRKCQKGLPWWFVFVGWFLVLATSGVSAYFTMLYGLTYGKERSISWLISMVVSFFESLFITQPVKVLGFAVFFALVLKTVDQDEYGDVSIDGTLSNTGNRIIRNMNYLSIFDDHLISVVKLQLKCLSTDDPDAVRIARRDSTCSFYKPPPPTDIEKMRNNMIKEQKVFALIREILIYVGFLWMLLLVAYGQRDPNAYYLTHHIRQSFSTGISETLNHKDIFIWANSSLLR----------NLYGQYPGFITDGNSKLVGNARIRQVRVRRDTCKIANPMQ--YSVRDCHAPYSWESEDMGSYSPGW-------------NQTRN-VNGSKTVLKPWYYQTQAKLRANPVWGGLALYKGGGFVVDLGPDQKNASRLLQYLFDNTWLDVYTRAVFVEFTVYNANVNLFCIVTLIFETTGVGTFQ-YRSEVQAVHLYQSTGGFHVFVMASEAIYYIFILYYMVVQGKLMKQQKWAYFKSKWNLLELAIIILSWSALSVFVKRTILGNRDIEFYQNNKDMFVSFNETATADAVLGYLIAFLVLLATIKLWHLLRLNPKLHMITSTLQRAWTDISGFIVVMTIMFLAYSIACNLMYGWRLNSYRTLLEAAQTIICLQLGIFNYDEVLDYNPVLGAFLIGSCIIFMT-FVVLNLFISVILVAFNEEQLHPTPSEEEEIVELMLMKVCSLL-GIKCKKKQTNADAPMTTASV 1122 HSP 2 Score: 97.0561 bits (240), Expect = 1.159e-19 Identity = 77/301 (25.58%), Postives = 126/301 (41.86%), Query Frame = 2 Query: 1316 FSAKIFIAPNMIDFKNVFANFASLLANSXXXXXXXXXXXXXXXXXXXXMWRKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVLLEIKRDEKFQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTGIISVLITYPCIFIASEIF 2218 F + F+ PN++D FA+ + N ++++ L DNDP EY Y++S++TG R A TSS + + L G G S +TD + +FE G + F++TT LG+L ++R+WH++SG P+ NL F +T +D + D HI + + S +TRVQ+V+ ++ M+++ MF+G ++ S +D G I TW Q GI S +I +P + IF Sbjct: 20 FGSSFFVMPNVVDVSRTAELFATFVNNP-----------------------------VVVKVTVLEDNDPLAEYRYLLSINTGQRRGASTSSQVTVTLQGSEGESEPHHLTDPEKP-VFERGGLDLFLLTTPFSLGELQSIRLWHDNSGYYPACNL---------------FFAKT------------------AKDFR--------------DGHIWFSVISRPPSSNFTRVQRVSCCFSLLLCTMLTSIMFWGIPSDPSEQT---MDLGKIEFTWQQVMIGIQSSIIMFPINLLIVSIF 240
BLAST of PKD1L-2 vs. Ensembl Zebrafish
Match: pkd1l2b (polycystic kidney disease 1 like 2b [Source:ZFIN;Acc:ZDB-GENE-141222-87]) HSP 1 Score: 144.436 bits (363), Expect = 5.898e-34 Identity = 154/639 (24.10%), Postives = 290/639 (45.38%), Query Frame = 2 Query: 2291 PKGFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPIILLIIFVLAKKLLGAVSTDQEANIDEFVK------DDLKKVLGANLN-------PPDQEKLEKIKKDKASGQRLSRVVGXXXXXXXXXXXXXXXXXXXRSQVTFDQTKMIRSRFIK--SNVQTYMDFYDWAQGILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISALVSKVYGNVPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTYAETIDENLFDYDKEMVDHV 4162 P F++VGW L+ V S +FT LY L++G ++S W+ + G + ++P+ ++ I + ++ V + E +D K D L +V A + PP +EK++++ Q+ +V + L ++ L +L +AY + F T+ I+ F K S+ D + WA +L + N G I + G RIRQ+RVK++TC ++ ++ CN Y+ +ED S+ W FN N ++ I A+ YQ+ + P G +Y GGGY+ LG ++ A ++ L + WLD+ TRA+F E TVYN N +LF + ++ E G + F +++ LY + M L+ +++Y L VV ++ + K + +QK YF + WNL+++ I LS S + + + I +K + SF + T +M + +++ + + + ++ ++ RA+ +S+L + L+A+ N++F + L + ++F + + I Y ++ + PA A+ + ++ F + S+FI I+ E + + ++E V+ V Sbjct: 1268 PWWFVYVGWVLVIGTSVISGYFTMLYGLKYGKDRSVSWIISNVTGFTQSLCFTEPVKVVFIGIFFALVMKKVEAEDE-EVDTLQKKTTAGSDGLSEVCFAQRDCTQSYYQPPPPGDIEKLRRNMIKQQKAQALVMEVLIFLGFLSMLLLVAYGQQDPNAFYLTQHIQQSFSKGISDSMKTNDVFVWANTVLLK----------NLFGQYPGFITDGNSKLVGNARIRQVRVKKDTCKVAKVMLHTVSQ--CNTPYSWGNEDMMSYGPGWE-------EFNSVN-------GSEEGITAWQYQSQSTLKALPVWGLTALYRGGGYVMDLGPDKQNATMKLQYLFNSTWLDEYTRAVFVEFTVYNANVDLFCIVTLILESSAVGAFQ-FRSVLQNVSLYSSVGSFMSFLMASRVIYFLFVVYYMFLQGKLLKRQKWAYFRNKWNLLDMAIIILSWSSLSLFIQKTVQGNIDIQYYQKHKNQFPSFHDTAAVDATLRYVMAFLVLLGCVKLWHLLRLSPKLYVIASSLQRAWDDMSTLTVVIFIILLAYSLACNLIFGWELYTYRTLPDAFTAIFSLQIGIFNYDEVMNSNPAL-GAVIISSCVLIATFVVLSLFISIILMAVTEERENHQPSEEEETVELV 1877 HSP 2 Score: 139.428 bits (350), Expect = 1.779e-32 Identity = 106/352 (30.11%), Postives = 171/352 (48.58%), Query Frame = 2 Query: 1184 SLGVASLTPRI--WNFNMEVWQDFSASVDDTSDISNINFKSNFLGTFSAKIFIAPNMID---FKNVFANFASLLANSXXXXXXXXXXXXXXXXXXXXMWRKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVL-LEIKRDEK-FQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTGIISVLITYPCIFIASEIF 2218 S+ V S+T + W W D+ V + L F F+ PN +D +F+NFA + VV+ I IF+ ++L RKD ++ ++ L DNDP EY Y++ + TG + TSS + + + G G +TD + +FE G V F++TT LGDL ++R+WH++SG P+W + +VI+D+QT + + F+C +WLS D E+V + + D K F N+F + DKH+ + S +T VQ+V+ ++ M+++ MF+G + S +D G I +TW Q G S L+ +P I IF Sbjct: 751 SVTVTSVTAQCIFWEEARANWSDYGCRVGPKTTPYVTQCLCTHLTFFGNSFFVMPNTVDPTKSAQLFSNFA----QNPVVVCFIGAIFVAFILTAAWARRKDLKDKAKVKVTVLDDNDPFAEYCYLVKISTGHRPGSSTSSRVIVTVQGMEGDCEPHHLTDPEKP-VFERGGVDLFLLTTPYSLGDLQSIRLWHDNSGNHPAWFVSTVVIKDLQTEQKWNFLCNSWLSVDVDDCTVEKVFPVASEVDMKGFSNVFFSKTTTDFCDKHLWYSVVCRPVNSSFTCVQRVSCCFSVLLCSMLTSIMFYGIPTDPSEQT---MDMGQIQLTWSQVMIGFESTLLVFPINLIIVGIF 1094
BLAST of PKD1L-2 vs. Ensembl Zebrafish
Match: pkd1l2b (polycystic kidney disease 1 like 2b [Source:ZFIN;Acc:ZDB-GENE-141222-87]) HSP 1 Score: 139.043 bits (349), Expect = 1.572e-32 Identity = 153/635 (24.09%), Postives = 290/635 (45.67%), Query Frame = 2 Query: 2291 PKGFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPIIL-------LIIFVLAKKLLGAV--STDQEANIDEFVKDDLKKVLGANLNPPDQEKLEKIKKDKASGQRLSRVVGXXXXXXXXXXXXXXXXXXXRSQVTFDQTKMIRSRFIK--SNVQTYMDFYDWAQGILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISALVSKVYGNVPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTYAETIDENLFDYDKEMVDHV 4162 P F++VGW L+ V S +FT LY L++G ++S W+ + G + ++P+ L + FV K + ++ STD + + F + D + + PP +EK++++ Q+ +V + L ++ L +L +AY + F T+ I+ F K S+ D + WA +L + N G I + G RIRQ+RVK++TC ++ ++ CN Y+ +ED S+ W FN N ++ I A+ YQ+ + P G +Y GGGY+ LG ++ A ++ L + WLD+ TRA+F E TVYN N +LF + ++ E G + F +++ LY + M L+ +++Y L VV ++ + K + +QK YF + WNL+++ I LS S + + + I +K + SF + T +M + +++ + + + ++ ++ RA+ +S+L + L+A+ N++F + L + ++F + + I Y ++ + PA + + + ++ F + S+FI I+ E + + ++E V+ V Sbjct: 395 PWWFVYVGWVLVIGTSVISGYFTMLYGLKYGKDRSVSWIISNVTGFTQSLCFTEPVKLSWSLRFRIKNFVSHKADVFSICNSTDGLSEVC-FAQRDCTQ---SYYQPPPPGDIEKLRRNMIKQQKAQALVMEVLIFLGFLSMLLLVAYGQQDPNAFYLTQHIQQSFSKGISDSMKTNDVFVWANTVLLK----------NLFGQYPGFITDGNSKLVGNARIRQVRVKKDTCKVAKVMLHTVSQ--CNTPYSWGNEDMMSYGPGWE-------EFNSVN-------GSEEGITAWQYQSQSTLKALPVWGLTALYRGGGYVMDLGPDKQNATMKLQYLFNSTWLDEYTRAVFVEFTVYNANVDLFCIVTLILESSAVGAFQ-FRSVLQNVSLYSSVGSFMSFLMASRVIYFLFVVYYMFLQGKLLKRQKWAYFRNKWNLLDMAIIILSWSSLSLFIQKTVQGNIDIQYYQKHKNQFPSFHDTAAVDATLRYVMAFLVLLGCVKLWHLLRLSPKLYVIASSLQRAWDDMSTLTVVIFIILLAYSLACNLIFGWELYTYRTLPDAFTAIFSLQIGIFNYDEVMNSNPALGAVIISSC-VLIATFVVLSLFISIILMAVTEERENHQPSEEEETVELV 997 HSP 2 Score: 107.842 bits (268), Expect = 6.015e-23 Identity = 67/217 (30.88%), Postives = 112/217 (51.61%), Query Frame = 2 Query: 1574 NAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVL-LEIKRDEK-FQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTGIISVLITYPCIFIASEIF 2218 N ++ + + + G G +TD + +FE G V F++TT LGDL ++R+WH++SG P+W + +VI+D+QT + + F+C +WLS D E+V + + D K F N+F + DKH+ + S +T VQ+V+ ++ M+++ MF+G + S +D G I +TW Q G S L+ +P I IF Sbjct: 9 NVISTLQVIVTVQGMEGDCEPHHLTDPEKP-VFERGGVDLFLLTTPYSLGDLQSIRLWHDNSGNHPAWFVSTVVIKDLQTEQKWNFLCNSWLSVDVDDCTVEKVFPVASEVDMKGFSNVFFSKTTTDFCDKHLWYSVVCRPVNSSFTCVQRVSCCFSVLLCSMLTSIMFYGIPTDPSEQT---MDMGQIQLTWSQVMIGFESTLLVFPINLIIVGIF 221
BLAST of PKD1L-2 vs. Ensembl Zebrafish
Match: pkd2 (polycystic kidney disease 2 [Source:NCBI gene;Acc:432387]) HSP 1 Score: 123.25 bits (308), Expect = 8.697e-28 Identity = 116/496 (23.39%), Postives = 224/496 (45.16%), Query Frame = 2 Query: 2771 NVQTYMDFYDWAQG-ILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISA-LVSKVYGNVPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTYAET-IDENLFDYDKEMVDHVWNIFNEMMT--GFKSSMKYTVPDALKKKA 4243 ++ T DF+ + +G LN Y ++WYNN ++ ++ + L G R+RQ+RV+ +C++ L +VY C Y+ +ED F K N + W + + +++ Q +T GG ++ L +E++A ++ L+ N WLD+ TRA+F + ++YNGN NLF +++L E P +GG + + ++ RL Y+ + + ++ + L V+ + E ++ + YF S WN +++L + LS+ II R + + L N Y +F+ L I F+S +++ K++ FNK ++ + T+ R L MF +A+ + ++F F+ + F + + + ++ E +Y+ + + ++F+ I+NDTY+E D + E+ D + +N M K S +PD+L++ A Sbjct: 208 SLSTMEDFWKFTEGPFLNGMYWELWYNN--KSLPENQSLIYYENLLLGVPRLRQLRVRNESCSVHEDLRDEVYD---CYNVYSPANEDKAPFGPK-----------NGTAWR--FKDESSLGESSYWGQVSTYGGGGYYQ-------------DLSRTREKSANQLQELKNNLWLDRGTRAVFLDFSIYNGNVNLFCIVRLLVEFPATGGA-VPSWQFQTVRLLRYVSSWDYFVGMCEVSFCLFVLYYLVEEALEIRLHRLRYFKSLWNCLDVLIVALSVPAIIMNICRTSAVSHRLHFLLENHSTYPNFEPLARLQVHFNNLAAIIVFLSWVKLFKFINFNKTMNQLSTTMSRCAKDLMGFAIMFFIVFLAYAQLAYLVFGTQVNDFSTFQACIFTQFRIILGDFDFSEIEEADSVL-GPIYFTTFVFFIFMILLNMFLAIINDTYSEVKADMAQQRSEMEITDLIKKSYNRAMVKLKLKKSSINDIPDSLQQAA 670
BLAST of PKD1L-2 vs. Ensembl Xenopus
Match: ENSXETT00000038579.1 (polycystin 1 like 2 (gene/pseudogene) [Source:NCBI gene;Acc:100486136]) HSP 1 Score: 172.17 bits (435), Expect = 3.283e-42 Identity = 156/619 (25.20%), Postives = 295/619 (47.66%), Query Frame = 2 Query: 2288 LPKGFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPIILLIIFVLAKKLLGAVSTDQEA----NIDEFVKDDLKKVLGANLN-----PPDQEKLEKIKKDKASGQRLSRVVGXXXXXXXXXXXXXXXXXXXRSQVTFDQTKMIRSRFIKS--NVQTYMDFYDWAQGILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISALVSKVYGNVPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTYAE 4111 LP F+F+GW L+ S FFT LY L +G + S +WL + + F +F++ P+ +L +L V + E N + D +LG+ + PP + K+K + Q++ ++ + L Y+ L +L +AY R ++ K I S F ++ +Y +F+ WA L NN+ G I + G R+RQIR+K+++C +++++ N C Y+L +E+ + D +WN + ++ V + + YQN++ G+P G Y GGGY+A LG +++ A ++++L +N WLD TRA+F E TVYN N NLF ++++FE N+ G ++S RLY + G I ++ +++Y L V+ + + K++ +K YF S WNL+EL I +S S + R ++ + +K +VSF++ + L+ +S I++ + N ++++ T+ RA+ +S + + +A+ N++F + + S ++ + + I Y ++ + P S L + ++ F + ++FI ++ ++E Sbjct: 1545 LPWWFVFIGWLLVAATSGVSAFFTMLYGLHYGKDSSIKWLISMAISFFESLFITQPLKVLGFAAFFALVLKKVEPEDEEETTINGNLSTPGDPNPLLGSRRDSNIYQPPPPTDITKMKNNYMKEQKVFALIREILAYLGFLWMLLLVAYGQRDPNSYYLNKHIESSFTDGFEDLCSYQEFFTWANTTL--------INNL--YGSHPGFITDGNSKLVGGARMRQIRIKKDSCPVASVLQSTIDN--CRAPYSLDAEEMGHY---------------DGSWNFSAITNATDVNSPWYYQNHSKLRGHPTWGKLATYRGGGYVADLGNERKYAHRVLQDLFSNIWLDSYTRAVFVEFTVYNANVNLFCIVKLMFET-NALGTFFTRANLQSVRLYPFTDGLHIFVVAAEVIYFLFVIYYMVVQGKRMKAEKWGYFRSKWNLLELALIIISWSALSVYVKRTILGTRDLRYYQEHKNEFVSFNETAAADAALGYLIAFLVLLSTIKLWHLLRLNPKLNMITATLRRAWGDISGFITVIVIMFLAYSIACNLIFGWKLNSYKTVFDSAKTMVSLQLGIFNYEEVLDYNPVLGSFLVGSCIIFMT-FVVLNLFISVILVAFSE 2134 HSP 2 Score: 151.369 bits (381), Expect = 8.084e-36 Identity = 101/338 (29.88%), Postives = 171/338 (50.59%), Query Frame = 2 Query: 1217 WNFNMEVWQDFSASVDDTSDISNINFKSNFLGTFSAKIFIAPNMIDFKNVFANFASLLANSXXXXXXXXXXXXXXXXXXXXMW--RKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVL-LEIKRDEK-FQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTGIISVLITYPCIFIASEIF 2218 W+ + W V + S+ N L F + + PN +D FA+ + N VV V + + L++ +W RKD +++ ++ L DNDP +Y Y+++V TG R A T+S + I L G G S ++D +FE G F++TT PLGD+ +R+WH++SG KPSW + ++++ D++ ++ + F+C +WLS D ++V + + D K F NLF G D HI + + + S +TRVQ+V+ ++ M+++ MF+G + A K+D G I TW + G S L+ +P + +IF Sbjct: 1047 WDEANQDWNSTGCHVGPKTTPSSTQCLCNHLTFFGSSFIVMPNAVDVSRTVELFATFVDNPVVVTTVGCIALVYVLVM---IWARRKDIQDNAKVKIIALEDNDPFAQYRYLVTVFTGHRRGAATTSKVTITLYGSDGESDPHHLSDP-EGPVFERGGEDIFLLTTLFPLGDVQTIRLWHDNSGDKPSWYVNRVLVHDMELDQKWYFLCNSWLSIEVGDCVLDKVFSVATEEDMKQFSNLFFMKTSKGFRDGHIWYSVFSRSPRSSFTRVQRVSCCFSLLLCTMLTSIMFWGVPTD---PAEQKMDMGKIEFTWQEVMIGFESSLLMFPINLLIVQIF 1377
BLAST of PKD1L-2 vs. Ensembl Xenopus
Match: PKD2L1 (polycystic kidney disease 2-like 1 [Source:NCBI gene;Acc:100495064]) HSP 1 Score: 122.094 bits (305), Expect = 6.289e-28 Identity = 117/448 (26.12%), Postives = 209/448 (46.65%), Query Frame = 2 Query: 2789 DFYDWAQG-ILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISALVSKVYGN--VPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTYAETIDE 4123 DF+ + QG +L+ Y WYNN++ T D T ++ + L G R+RQ++VK N+C +V K + + V C + Y+ EDT F + N + W Y GG + G Y GGGY L + + + ++ L++N WLD+ TRA+F + +VYN N NLF ++++ E P +GG + + +R+ +L Y+ G ++ +I++ + + + EI ++ K YF+S WN+++++ I LSL I R M + L N Y F+ W + ++ F + I++ KY+ FNK ++ + T+ R + MF A+ +G +LF F+ + + F + + Y D + +Y+ + F + ++F+ I+NDTY+E +E Sbjct: 86 DFWSYLQGPMLDGLYWTKWYNNVSLT-DNTNSLIYYENLLLGVPRMRQLKVKNNSC----MVYKDFKDEIVGCFDVYSKDKEDTSQFGL-----------INGTAWT---------------YYTEEELGGSSYWGKITTYSGGGYYIDLELTKRDSLRQLQTLKSNLWLDRGTRAVFVDFSVYNANINLFCVLRLVVEFPATGG-AIPSWQIRTVKLIRYVSGWDYFIIGCEIVFCIFIFYYVVEEILELRIHKFRYFTSIWNILDVIVILLSLVAIGFHIFRTMEVNRLMGTLLKNPTIYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAIMFFIVFFAYAQLGYLLFGTQVENFSTFVKCIFTQFRIILGDFDY-DAIDNANRVLGPIYFVTYVFFVFFVLLNMFLAIINDTYSEVKEE 500
BLAST of PKD1L-2 vs. Ensembl Xenopus
Match: PKD2L1 (polycystic kidney disease 2-like 1 [Source:NCBI gene;Acc:100495064]) HSP 1 Score: 122.094 bits (305), Expect = 1.255e-27 Identity = 117/448 (26.12%), Postives = 209/448 (46.65%), Query Frame = 2 Query: 2789 DFYDWAQG-ILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISALVSKVYGN--VPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTYAETIDE 4123 DF+ + QG +L+ Y WYNN++ T D T ++ + L G R+RQ++VK N+C +V K + + V C + Y+ EDT F + N + W Y GG + G Y GGGY L + + + ++ L++N WLD+ TRA+F + +VYN N NLF ++++ E P +GG + + +R+ +L Y+ G ++ +I++ + + + EI ++ K YF+S WN+++++ I LSL I R M + L N Y F+ W + ++ F + I++ KY+ FNK ++ + T+ R + MF A+ +G +LF F+ + + F + + Y D + +Y+ + F + ++F+ I+NDTY+E +E Sbjct: 100 DFWSYLQGPMLDGLYWTKWYNNVSLT-DNTNSLIYYENLLLGVPRMRQLKVKNNSC----MVYKDFKDEIVGCFDVYSKDKEDTSQFGL-----------INGTAWT---------------YYTEEELGGSSYWGKITTYSGGGYYIDLELTKRDSLRQLQTLKSNLWLDRGTRAVFVDFSVYNANINLFCVLRLVVEFPATGG-AIPSWQIRTVKLIRYVSGWDYFIIGCEIVFCIFIFYYVVEEILELRIHKFRYFTSIWNILDVIVILLSLVAIGFHIFRTMEVNRLMGTLLKNPTIYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAIMFFIVFFAYAQLGYLLFGTQVENFSTFVKCIFTQFRIILGDFDY-DAIDNANRVLGPIYFVTYVFFVFFVLLNMFLAIINDTYSEVKEE 514
BLAST of PKD1L-2 vs. Ensembl Xenopus
Match: PKD2L1 (polycystic kidney disease 2-like 1 [Source:NCBI gene;Acc:100495064]) HSP 1 Score: 118.242 bits (295), Expect = 2.926e-26 Identity = 106/403 (26.30%), Postives = 187/403 (46.40%), Query Frame = 2 Query: 2789 DFYDWAQG-ILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISALVSKVYGN--VPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKY 3988 DF+ + QG +L+ Y WYNN++ T D T ++ + L G R+RQ++VK N+C +V K + + V C + Y+ EDT F + N + W Y GG + G Y GGGY L + + + ++ L++N WLD+ TRA+F + +VYN N NLF ++++ E P +GG + + +R+ +L Y+ G ++ +I++ + + + EI ++ K YF+S WN+++++ I LSL I R M + L N Y F+ W + ++ F + I++ KY+ FNK ++ + T+ R + MF A+ +G +LF F+ + + F + + Y Sbjct: 162 DFWSYLQGPMLDGLYWTKWYNNVSLT-DNTNSLIYYENLLLGVPRMRQLKVKNNSC----MVYKDFKDEIVGCFDVYSKDKEDTSQFGL-----------INGTAWT---------------YYTEEELGGSSYWGKITTYSGGGYYIDLELTKRDSLRQLQTLKSNLWLDRGTRAVFVDFSVYNANINLFCVLRLVVEFPATGG-AIPSWQIRTVKLIRYVSGWDYFIIGCEIVFCIFIFYYVVEEILELRIHKFRYFTSIWNILDVIVILLSLVAIGFHIFRTMEVNRLMGTLLKNPTIYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAIMFFIVFFAYAQLGYLLFGTQVENFSTFVKCIFTQFRIILGDFDY 532
BLAST of PKD1L-2 vs. Ensembl Xenopus
Match: PKD2L1 (polycystic kidney disease 2-like 1 [Source:NCBI gene;Acc:100495064]) HSP 1 Score: 117.472 bits (293), Expect = 3.291e-26 Identity = 102/403 (25.31%), Postives = 189/403 (46.90%), Query Frame = 2 Query: 2789 DFYDWAQG-ILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISALVSKVYGN--VPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKY 3988 DF+ + QG +L+ Y WYNN++ T D T ++ + L G R+RQ++VK N+C +V K + + V C + Y+ EDT F + N + W Y + + +++ + T SGG + L + + + ++ L++N WLD+ TRA+F + +VYN N NLF ++++ E P +GG + + +R+ +L Y+ G ++ +I++ + + + EI ++ K YF+S WN+++++ I LSL I R M + L N Y F+ W + ++ F + I++ KY+ FNK ++ + T+ R + MF A+ +G +LF F+ + + F + + Y Sbjct: 86 DFWSYLQGPMLDGLYWTKWYNNVSLT-DNTNSLIYYENLLLGVPRMRQLKVKNNSC----MVYKDFKDEIVGCFDVYSKDKEDTSQFGL-----------INGTAWT--YYTEEELGGSSYWGKITTYSGGGYY-------------IDLELTKRDSLRQLQTLKSNLWLDRGTRAVFVDFSVYNANINLFCVLRLVVEFPATGG-AIPSWQIRTVKLIRYVSGWDYFIIGCEIVFCIFIFYYVVEEILELRIHKFRYFTSIWNILDVIVILLSLVAIGFHIFRTMEVNRLMGTLLKNPTIYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAIMFFIVFFAYAQLGYLLFGTQVENFSTFVKCIFTQFRIILGDFDY 456
BLAST of PKD1L-2 vs. Ensembl Mouse
Match: Pkd1l2 (polycystic kidney disease 1 like 2 [Source:MGI Symbol;Acc:MGI:2664668]) HSP 1 Score: 158.303 bits (399), Expect = 4.394e-38 Identity = 105/338 (31.07%), Postives = 174/338 (51.48%), Query Frame = 2 Query: 1217 WNFNMEVWQDFSASVDDTSDISNINFKSNFLGTFSAKIFIAPNMIDFKNVFANFASLLANSXXXXXXXXXXXXXXXXXXXXMW--RKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVL-LEIKRDEK-FQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTGIISVLITYPCIFIASEIF 2218 W+ E W D V + S + N L F + + PN ID + FA+ N VV V L + L+L +W RKD ++ ++ L DNDP +Y Y+++V+TG R A TSS + + L G G S ++D +FE G V F+++T PLG+L +LR+WH++SG +PSW + ++++ D ++ + F+C +WLS D ++V + ++D K F +LF +G D HI + + S +TRVQ+V+ +M M+++ MF+G + A K+D G I TW + G+ S ++ +P + +IF Sbjct: 1286 WDETQETWDDSGCQVGPRTTPSQTHCLCNHLTFFGSSFLVMPNAIDVRQTAELFATFEDNPVVVTTVGCLCMLYVLVL---IWARRKDIQDQAKVKVVVLEDNDPFAQYHYLVTVYTGHRRGAATSSKVTLTLYGSDGESEPHHLSDP-DAAVFERGGVDVFLLSTLFPLGELQSLRLWHDNSGDRPSWYVSRVLVYDSVVDRKWYFLCNSWLSVDVGDCVLDKVFPVATEQDRKQFSHLFFTKTSTGFQDGHIWYSVFCSATRSSFTRVQRVSCCFSMLLCTMLTSIMFWGVPKD---PAEQKMDLGKIEFTWQEVMIGLESSILMFPINLLIVQIF 1616 HSP 2 Score: 135.191 bits (339), Expect = 4.963e-31 Identity = 155/641 (24.18%), Postives = 276/641 (43.06%), Query Frame = 2 Query: 2288 LPKGFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPIILL---IIFVLAKKLLGAVSTDQEANIDEFVKDDLKKVLGA-----------NLNPPDQEKLEKIKKDKASGQRLSRVVGXXXXXXXXXXXXXXXXXXXRSQVTFDQTKMIRSRFIK--SNVQTYMDFYDWAQGILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISALVSKVYGNVPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGV--RSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTYAETIDENLFDYDKEMVD 4156 LP + VGW L+ + FFT LY L +G S +WL + V VF++ P+ +L F L K D E + F G PP +EK+K + Q+ ++ + L Y+ L +L +AY R + + + F + S V + F++WA L + N G + + G IRQ+RV+ ++C ++ + C+ Y+L ED + W N+S ++N+SN A+ YQ+ + GYP G +YGGGGY+ LG + A+ I++ L N+WLD LTRA+F E TVYN N NLF T+ + E + GL F V +S RLY + G ++ ++ Y L + + + K + KQK YF S WNL+E+ I S S ++ R ++ + ++ +SF + + ++ +S +++ + N ++++ + RA+ +S + + L+A+ N++F + L + ++ + + I Y ++ + P S L + F + ++FI ++ ++E + + E+ D Sbjct: 1814 LPWWCVLVGWLLVATTSGVAAFFTMLYGLHYGRVSSLKWLISMAVSFVESVFITQPLKVLGFAAFFALVLK-----REDDEETLPLFPGHLSSPGPGVLFRSRRHSSERAYQPPPMAAIEKMKTTRLKEQKAFALIREILAYLAFLWMLLLVAYGQRDPNAYHFHRHLERSFSQGFSPVLGFRGFFEWANTTLVK----------NLYGHHPGFVTDGNSKLVGSAHIRQVRVRESSCAVAQQLQDSLDG--CHGPYSLGIEDLVDYGEGW----NAS-AYNNSN----------GFPQAWRYQSQSQRRGYPMWGKLTLYGGGGYVVPLGTDHQSASRILQYLFDNSWLDALTRAVFVEFTVYNANVNLFCTVTLTLE---TSGLGTFFSHVTLQSLRLYPFTDGWHPFVVAAELTYFLFLFYYMVVQGKLMRKQKWGYFCSKWNLLEVAIILASWSALVVFVKRTILADRDLQRYREHRDEGISFSETAAADAALGYIIAFLVLLSTVKLWHLLRLNPKMNMITSALRRAWGDISGFVAVILIMLLAYSFASNLVFGWKLRSYKTLFDAAETMVSLQLGIFNYEEVLDYSPILGSLLIGSC-IVFMTFVVLNLFISVILVAFSEEQKSDQLWEEGEIAD 2418
BLAST of PKD1L-2 vs. Ensembl Mouse
Match: Pkd1l2 (polycystic kidney disease 1 like 2 [Source:MGI Symbol;Acc:MGI:2664668]) HSP 1 Score: 158.303 bits (399), Expect = 4.545e-38 Identity = 105/338 (31.07%), Postives = 174/338 (51.48%), Query Frame = 2 Query: 1217 WNFNMEVWQDFSASVDDTSDISNINFKSNFLGTFSAKIFIAPNMIDFKNVFANFASLLANSXXXXXXXXXXXXXXXXXXXXMW--RKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVL-LEIKRDEK-FQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTGIISVLITYPCIFIASEIF 2218 W+ E W D V + S + N L F + + PN ID + FA+ N VV V L + L+L +W RKD ++ ++ L DNDP +Y Y+++V+TG R A TSS + + L G G S ++D +FE G V F+++T PLG+L +LR+WH++SG +PSW + ++++ D ++ + F+C +WLS D ++V + ++D K F +LF +G D HI + + S +TRVQ+V+ +M M+++ MF+G + A K+D G I TW + G+ S ++ +P + +IF Sbjct: 1285 WDETQETWDDSGCQVGPRTTPSQTHCLCNHLTFFGSSFLVMPNAIDVRQTAELFATFEDNPVVVTTVGCLCMLYVLVL---IWARRKDIQDQAKVKVVVLEDNDPFAQYHYLVTVYTGHRRGAATSSKVTLTLYGSDGESEPHHLSDP-DAAVFERGGVDVFLLSTLFPLGELQSLRLWHDNSGDRPSWYVSRVLVYDSVVDRKWYFLCNSWLSVDVGDCVLDKVFPVATEQDRKQFSHLFFTKTSTGFQDGHIWYSVFCSATRSSFTRVQRVSCCFSMLLCTMLTSIMFWGVPKD---PAEQKMDLGKIEFTWQEVMIGLESSILMFPINLLIVQIF 1615 HSP 2 Score: 135.191 bits (339), Expect = 5.132e-31 Identity = 155/641 (24.18%), Postives = 276/641 (43.06%), Query Frame = 2 Query: 2288 LPKGFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPIILL---IIFVLAKKLLGAVSTDQEANIDEFVKDDLKKVLGA-----------NLNPPDQEKLEKIKKDKASGQRLSRVVGXXXXXXXXXXXXXXXXXXXRSQVTFDQTKMIRSRFIK--SNVQTYMDFYDWAQGILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISALVSKVYGNVPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGV--RSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTYAETIDENLFDYDKEMVD 4156 LP + VGW L+ + FFT LY L +G S +WL + V VF++ P+ +L F L K D E + F G PP +EK+K + Q+ ++ + L Y+ L +L +AY R + + + F + S V + F++WA L + N G + + G IRQ+RV+ ++C ++ + C+ Y+L ED + W N+S ++N+SN A+ YQ+ + GYP G +YGGGGY+ LG + A+ I++ L N+WLD LTRA+F E TVYN N NLF T+ + E + GL F V +S RLY + G ++ ++ Y L + + + K + KQK YF S WNL+E+ I S S ++ R ++ + ++ +SF + + ++ +S +++ + N ++++ + RA+ +S + + L+A+ N++F + L + ++ + + I Y ++ + P S L + F + ++FI ++ ++E + + E+ D Sbjct: 1813 LPWWCVLVGWLLVATTSGVAAFFTMLYGLHYGRVSSLKWLISMAVSFVESVFITQPLKVLGFAAFFALVLK-----REDDEETLPLFPGHLSSPGPGVLFRSRRHSSERAYQPPPMAAIEKMKTTRLKEQKAFALIREILAYLAFLWMLLLVAYGQRDPNAYHFHRHLERSFSQGFSPVLGFRGFFEWANTTLVK----------NLYGHHPGFVTDGNSKLVGSAHIRQVRVRESSCAVAQQLQDSLDG--CHGPYSLGIEDLVDYGEGW----NAS-AYNNSN----------GFPQAWRYQSQSQRRGYPMWGKLTLYGGGGYVVPLGTDHQSASRILQYLFDNSWLDALTRAVFVEFTVYNANVNLFCTVTLTLE---TSGLGTFFSHVTLQSLRLYPFTDGWHPFVVAAELTYFLFLFYYMVVQGKLMRKQKWGYFCSKWNLLEVAIILASWSALVVFVKRTILADRDLQRYREHRDEGISFSETAAADAALGYIIAFLVLLSTVKLWHLLRLNPKMNMITSALRRAWGDISGFVAVILIMLLAYSFASNLVFGWKLRSYKTLFDAAETMVSLQLGIFNYEEVLDYSPILGSLLIGSC-IVFMTFVVLNLFISVILVAFSEEQKSDQLWEEGEIAD 2417
BLAST of PKD1L-2 vs. Ensembl Mouse
Match: Pkd1l3 (polycystic kidney disease 1 like 3 [Source:MGI Symbol;Acc:MGI:2664670]) HSP 1 Score: 132.109 bits (331), Expect = 3.439e-30 Identity = 93/338 (27.51%), Postives = 158/338 (46.75%), Query Frame = 2 Query: 1217 WNFNMEVWQDFSASVDDTSDISNINFKSNFLGTFSAKIFIAPNMIDFKNVFANFASLLANSXXXXXXXXXXXXXXXXXXXXMW--RKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVLLEIKRDE--KFQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTGIISVLITYPCIFIASEIF 2218 W+ W+ V S I + L FS+ FI P +D +N LL + + V +L +L +++ MW RKDR + ++ L DNDP Y+I V+TG R A T++ + I L G G S + D + +FE G + F+++T S LGDL LR+WH++SG PSW + ++++ D+ T K + F C WL+ + +RV R E F++LF V ++ + + +TRVQ+++ + + MV N MF+ + ++ G +++T + I + +I +P I +F Sbjct: 1014 WDRYNRTWKSDGCQVGPKSTILKTQCLCDHLTFFSSDFFIVPRTVDVENTIK---LLLHVTNNPVGVSLLSSLLGFYILLAMWASRKDREDMQKVKVTVLADNDPSSASHYLIQVYTGYRRRAATTAKVVITLYGSEGHSEPHHLCDPEKT-VFERGALDVFLLSTGSWLGDLHGLRLWHDNSGDSPSWYVSQVIVSDMTTRKKWHFQCNCWLAVDLGNCERDRVFTPASRSELSSFRHLFSSTIVEKFTQDYLWLSVATRHPWNQFTRVQRLSCCMALLLCDMVINIMFWKMGGTTAKRGTEQL--GPLAVTLSELLVSIQTSIILFPIHLIFGRLF 1345 HSP 2 Score: 118.627 bits (296), Expect = 4.601e-26 Identity = 148/607 (24.38%), Postives = 262/607 (43.16%), Query Frame = 2 Query: 2261 EAKMKKMFLLPKGFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPI---ILLIIFVLAKKLLGAVSTDQEANIDEFVKDDLKKVLGA-----NLNP----PDQEKLEKIKKDKASGQRLSRVVGXXXXXXXXXXXXXXXXXXXRSQVTFDQTKMIRSRFIK--SNVQTYMDFYDWAQGILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISALVSKVYGNVPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNM-IVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFI--CFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSAL 4030 E K F L + W LL V +AS FF LYSL+ +++ W+ + + + +F+S PI L ++F L + ++ D+E + V K A NP P L K + KA ++LS++ G L +L L LL Y A+ F + I RF S ++T DFY WA G L P ++ GD I + G IRQ R+ N + K + P ++ ED ++ W P +++++ DS W+ YQN GGYP +G Y GGGY+ LG A ++++L+ WLD T+A+F E TV+N N NL + ++ E S G+ F ++ L ++ Q++Y L V + + ++ +Q+ +F+ NL++ + +S SI+ + + + + + ++ ++SF +A L G + +RV + + + ++ T+ +A+ ++ LGF+ I L ++ N+LF + + + S V++ G+ + K+ ++ P S L Sbjct: 1517 EGKKPMSFCLFRWLKCSCWLLLGVISLASAFFITLYSLELDKDQATSWVISMMLSVLQDIFISQPIKVIFLTLLFSLMANHMPWLNKDKEQHARRIVALWAKCPWSAPGLRDKNNPIYTAPAMNNLAKPTR-KAWKKQLSKLTGGTLVQILFLTLLMTTVYSAKDSSRFFLHRAIWKRFSHRFSEIKTVEDFYPWANGTL---LPNLY-------GDYRGFITDGNSFLLGNVLIRQTRIP-NDIFFPGSLHKQMKSPPQHQ------EDRENYGAGWVP-PDTNITKVDSIWH---------------YQNQESLGGYPIQGELATYSGGGYVVRLGRNHSAATRVLQHLEQRRWLDHCTKALFVEFTVFNANVNLLCAVTLILE---SSGVGTFLTSLQLDSLTSLQSSERGFAWIVSQVVYYLLVCYYAFIQGCRLKRQRLAFFTRKRNLLDTSIVLISFSILGLSMQSLSLLHKKMQQYHCDRDRFISFYEALRVNSAVTHLRGFLLLFATVRVWDLLRHHAQLQVINKTLSKAWDEV--LGFILIIVVLLSSYAMTFNLLFGWSISDYQSFFRSIVTVVGLLMGTSKHKEVIALYPILGSLL 2084
BLAST of PKD1L-2 vs. Ensembl Mouse
Match: Pkd1l3 (polycystic kidney disease 1 like 3 [Source:MGI Symbol;Acc:MGI:2664670]) HSP 1 Score: 131.724 bits (330), Expect = 4.771e-30 Identity = 93/338 (27.51%), Postives = 158/338 (46.75%), Query Frame = 2 Query: 1217 WNFNMEVWQDFSASVDDTSDISNINFKSNFLGTFSAKIFIAPNMIDFKNVFANFASLLANSXXXXXXXXXXXXXXXXXXXXMW--RKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVLLEIKRDE--KFQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTGIISVLITYPCIFIASEIF 2218 W+ W+ V S I + L FS+ FI P +D +N LL + + V +L +L +++ MW RKDR + ++ L DNDP Y+I V+TG R A T++ + I L G G S + D + +FE G + F+++T S LGDL LR+WH++SG PSW + ++++ D+ T K + F C WL+ + +RV R E F++LF V ++ + + +TRVQ+++ + + MV N MF+ + ++ G +++T + I + +I +P I +F Sbjct: 1014 WDRYNRTWKSDGCQVGPKSTILKTQCLCDHLTFFSSDFFIVPRTVDVENTIK---LLLHVTNNPVGVSLLSSLLGFYILLAMWASRKDREDMQKVKVTVLADNDPSSASHYLIQVYTGYRRRAATTAKVVITLYGSEGHSEPHHLCDPEKT-VFERGALDVFLLSTGSWLGDLHGLRLWHDNSGDSPSWYVSQVIVSDMTTRKKWHFQCNCWLAVDLGNCERDRVFTPASRSELSSFRHLFSSTIVEKFTQDYLWLSVATRHPWNQFTRVQRLSCCMALLLCDMVINIMFWKMGGTTAKRGTEQL--GPLAVTLSELLVSIQTSIILFPIHLIFGRLF 1345 HSP 2 Score: 117.857 bits (294), Expect = 8.352e-26 Identity = 148/607 (24.38%), Postives = 262/607 (43.16%), Query Frame = 2 Query: 2261 EAKMKKMFLLPKGFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPI---ILLIIFVLAKKLLGAVSTDQEANIDEFVKDDLKKVLGA-----NLNP----PDQEKLEKIKKDKASGQRLSRVVGXXXXXXXXXXXXXXXXXXXRSQVTFDQTKMIRSRFIK--SNVQTYMDFYDWAQGILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISALVSKVYGNVPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNM-IVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFI--CFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSAL 4030 E K F L + W LL V +AS FF LYSL+ +++ W+ + + + +F+S PI L ++F L + ++ D+E + V K A NP P L K + KA ++LS++ G L +L L LL Y A+ F + I RF S ++T DFY WA G L P ++ GD I + G IRQ R+ N + K + P ++ ED ++ W P +++++ DS W+ YQN GGYP +G Y GGGY+ LG A ++++L+ WLD T+A+F E TV+N N NL + ++ E S G+ F ++ L ++ Q++Y L V + + ++ +Q+ +F+ NL++ + +S SI+ + + + + + ++ ++SF +A L G + +RV + + + ++ T+ +A+ ++ LGF+ I L ++ N+LF + + + S V++ G+ + K+ ++ P S L Sbjct: 1517 EGKKPMSFCLFRWLKCSCWLLLGVISLASAFFITLYSLELDKDQATSWVISMMLSVLQDIFISQPIKVIFLTLLFSLMANHMPWLNKDKEQHARRIVALWAKCPWSAPGLRDKNNPIYTAPAMNNLAKPTR-KAWKKQLSKLTGGTLVQILFLTLLMTTVYSAKDSSRFFLHRAIWKRFSHRFSEIKTVEDFYPWANGTL---LPNLY-------GDYRGFITDGNSFLLGNVLIRQTRIP-NDIFFPGSLHKQMKSPPQHQ------EDRENYGAGWVP-PDTNITKVDSIWH---------------YQNQESLGGYPIQGELATYSGGGYVVRLGRNHSAATRVLQHLEQRRWLDHCTKALFVEFTVFNANVNLLCAVTLILE---SSGVGTFLTSLQLDSLTSLQSSERGFAWIVSQVVYYLLVCYYAFIQGCRLKRQRLAFFTRKRNLLDTSIVLISFSILGLSMQSLSLLHKKMQQYHCDRDRFISFYEALRVNSAVTHLRGFLLLFATVRVWDLLRHHAQLQVINKTLSKAWDEV--LGFILIIVVLLSSYAMTFNLLFGWSISDYQSFFRSIVTVVGLLMGTSKHKEVIALYPILGSLL 2084
BLAST of PKD1L-2 vs. Ensembl Mouse
Match: Pkd1l3 (polycystic kidney disease 1 like 3 [Source:MGI Symbol;Acc:MGI:2664670]) HSP 1 Score: 131.724 bits (330), Expect = 5.611e-30 Identity = 93/338 (27.51%), Postives = 158/338 (46.75%), Query Frame = 2 Query: 1217 WNFNMEVWQDFSASVDDTSDISNINFKSNFLGTFSAKIFIAPNMIDFKNVFANFASLLANSXXXXXXXXXXXXXXXXXXXXMW--RKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVLLEIKRDE--KFQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTGIISVLITYPCIFIASEIF 2218 W+ W+ V S I + L FS+ FI P +D +N LL + + V +L +L +++ MW RKDR + ++ L DNDP Y+I V+TG R A T++ + I L G G S + D + +FE G + F+++T S LGDL LR+WH++SG PSW + ++++ D+ T K + F C WL+ + +RV R E F++LF V ++ + + +TRVQ+++ + + MV N MF+ + ++ G +++T + I + +I +P I +F Sbjct: 1024 WDRYNRTWKSDGCQVGPKSTILKTQCLCDHLTFFSSDFFIVPRTVDVENTIK---LLLHVTNNPVGVSLLSSLLGFYILLAMWASRKDREDMQKVKVTVLADNDPSSASHYLIQVYTGYRRRAATTAKVVITLYGSEGHSEPHHLCDPEKT-VFERGALDVFLLSTGSWLGDLHGLRLWHDNSGDSPSWYVSQVIVSDMTTRKKWHFQCNCWLAVDLGNCERDRVFTPASRSELSSFRHLFSSTIVEKFTQDYLWLSVATRHPWNQFTRVQRLSCCMALLLCDMVINIMFWKMGGTTAKRGTEQL--GPLAVTLSELLVSIQTSIILFPIHLIFGRLF 1355 HSP 2 Score: 117.857 bits (294), Expect = 8.578e-26 Identity = 148/607 (24.38%), Postives = 262/607 (43.16%), Query Frame = 2 Query: 2261 EAKMKKMFLLPKGFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPI---ILLIIFVLAKKLLGAVSTDQEANIDEFVKDDLKKVLGA-----NLNP----PDQEKLEKIKKDKASGQRLSRVVGXXXXXXXXXXXXXXXXXXXRSQVTFDQTKMIRSRFIK--SNVQTYMDFYDWAQGILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISALVSKVYGNVPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNM-IVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFI--CFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSAL 4030 E K F L + W LL V +AS FF LYSL+ +++ W+ + + + +F+S PI L ++F L + ++ D+E + V K A NP P L K + KA ++LS++ G L +L L LL Y A+ F + I RF S ++T DFY WA G L P ++ GD I + G IRQ R+ N + K + P ++ ED ++ W P +++++ DS W+ YQN GGYP +G Y GGGY+ LG A ++++L+ WLD T+A+F E TV+N N NL + ++ E S G+ F ++ L ++ Q++Y L V + + ++ +Q+ +F+ NL++ + +S SI+ + + + + + ++ ++SF +A L G + +RV + + + ++ T+ +A+ ++ LGF+ I L ++ N+LF + + + S V++ G+ + K+ ++ P S L Sbjct: 1527 EGKKPMSFCLFRWLKCSCWLLLGVISLASAFFITLYSLELDKDQATSWVISMMLSVLQDIFISQPIKVIFLTLLFSLMANHMPWLNKDKEQHARRIVALWAKCPWSAPGLRDKNNPIYTAPAMNNLAKPTR-KAWKKQLSKLTGGTLVQILFLTLLMTTVYSAKDSSRFFLHRAIWKRFSHRFSEIKTVEDFYPWANGTL---LPNLY-------GDYRGFITDGNSFLLGNVLIRQTRIP-NDIFFPGSLHKQMKSPPQHQ------EDRENYGAGWVP-PDTNITKVDSIWH---------------YQNQESLGGYPIQGELATYSGGGYVVRLGRNHSAATRVLQHLEQRRWLDHCTKALFVEFTVFNANVNLLCAVTLILE---SSGVGTFLTSLQLDSLTSLQSSERGFAWIVSQVVYYLLVCYYAFIQGCRLKRQRLAFFTRKRNLLDTSIVLISFSILGLSMQSLSLLHKKMQQYHCDRDRFISFYEALRVNSAVTHLRGFLLLFATVRVWDLLRHHAQLQVINKTLSKAWDEV--LGFILIIVVLLSSYAMTFNLLFGWSISDYQSFFRSIVTVVGLLMGTSKHKEVIALYPILGSLL 2094
BLAST of PKD1L-2 vs. UniProt/SwissProt
Match: sp|Q7TN88|PK1L2_MOUSE (Polycystic kidney disease protein 1-like 2 OS=Mus musculus OX=10090 GN=Pkd1l2 PE=2 SV=1) HSP 1 Score: 158.303 bits (399), Expect = 3.073e-37 Identity = 105/338 (31.07%), Postives = 174/338 (51.48%), Query Frame = 2 Query: 1217 WNFNMEVWQDFSASVDDTSDISNINFKSNFLGTFSAKIFIAPNMIDFKNVFANFASLLANSXXXXXXXXXXXXXXXXXXXXMW--RKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVL-LEIKRDEK-FQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTGIISVLITYPCIFIASEIF 2218 W+ E W D V + S + N L F + + PN ID + FA+ N VV V L + L+L +W RKD ++ ++ L DNDP +Y Y+++V+TG R A TSS + + L G G S ++D +FE G V F+++T PLG+L +LR+WH++SG +PSW + ++++ D ++ + F+C +WLS D ++V + ++D K F +LF +G D HI + + S +TRVQ+V+ +M M+++ MF+G + A K+D G I TW + G+ S ++ +P + +IF Sbjct: 1286 WDETQETWDDSGCQVGPRTTPSQTHCLCNHLTFFGSSFLVMPNAIDVRQTAELFATFEDNPVVVTTVGCLCMLYVLVL---IWARRKDIQDQAKVKVVVLEDNDPFAQYHYLVTVYTGHRRGAATSSKVTLTLYGSDGESEPHHLSDP-DAAVFERGGVDVFLLSTLFPLGELQSLRLWHDNSGDRPSWYVSRVLVYDSVVDRKWYFLCNSWLSVDVGDCVLDKVFPVATEQDRKQFSHLFFTKTSTGFQDGHIWYSVFCSATRSSFTRVQRVSCCFSMLLCTMLTSIMFWGVPKD---PAEQKMDLGKIEFTWQEVMIGLESSILMFPINLLIVQIF 1616 HSP 2 Score: 132.88 bits (333), Expect = 1.667e-29 Identity = 157/647 (24.27%), Postives = 277/647 (42.81%), Query Frame = 2 Query: 2288 LPKGFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPIILL---IIFVLAKKLLGAVSTDQEANIDEFVKDDLKKVLGA-----------NLNPPDQEKLEKIKKDKASGQRLSRVVGXXXXXXXXXXXXXXXXXXXRSQVTFDQTKMIRSRFIK--SNVQTYMDFYDWAQGILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISALVSKVYGNVPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGV--RSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCI------LMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTYAETIDENLFDYDKEMVD 4156 LP + VGW L+ + FFT LY L +G S +WL + V VF++ P+ +L F L K D E + F G PP +EK+K + Q+ ++ + L Y+ L +L +AY R + + + F + S V + F++WA L + N G + + G IRQ+RV+ ++C ++ + C+ Y+L ED + W N+S ++N+SN A+ YQ+ + GYP G +YGGGGY+ LG + A+ I++ L N+WLD LTRA+F E TVYN N NLF T+ + E + GL F V +S RLY + G ++ ++ Y L + + + K + KQK YF S WNL+E+ I S S ++V + + + + Y + S+ ET+ ++ +S +++ + N ++++ + RA+ +S + + L+A+ N++F + L + ++ + + I Y ++ + P S L + F + ++FI ++ ++E + + E+ D Sbjct: 1814 LPWWCVLVGWLLVATTSGVAAFFTMLYGLHYGRVSSLKWLISMAVSFVESVFITQPLKVLGFAAFFALVLK-----REDDEETLPLFPGHLSSPGPGVLFRSRRHSSERAYQPPPMAAIEKMKTTRLKEQKAFALIREILAYLAFLWMLLLVAYGQRDPNAYHFHRHLERSFSQGFSPVLGFRGFFEWANTTLVK----------NLYGHHPGFVTDGNSKLVGSAHIRQVRVRESSCAVAQQLQDSLDG--CHGPYSLGIEDLVDYGEGW----NAS-AYNNSN----------GFPQAWRYQSQSQRRGYPMWGKLTLYGGGGYVVPLGTDHQSASRILQYLFDNSWLDALTRAVFVEFTVYNANVNLFCTVTLTLE---TSGLGTFFSHVTLQSLRLYPFTDGWHPFVVAAELTYFLFLFYYMVVQGKLMRKQKWGYFCSKWNLLEVAIILASWSA-------LVVFVKRTILADRDLQRYREHREGISFSETAAADAALGYIIAFLVLLSTVKLWHLLRLNPKMNMITSALRRAWGDISGFVAVILIMLLAYSFASNLVFGWKLRSYKTLFDAAETMVSLQLGIFNYEEVLDYSPILGSLLIGSC-IVFMTFVVLNLFISVILVAFSEEQKSDQLSEEGEIAD 2417
BLAST of PKD1L-2 vs. UniProt/SwissProt
Match: sp|Q7Z442|PK1L2_HUMAN (Polycystic kidney disease protein 1-like 2 OS=Homo sapiens OX=9606 GN=PKD1L2 PE=1 SV=5) HSP 1 Score: 149.828 bits (377), Expect = 1.078e-34 Identity = 100/338 (29.59%), Postives = 171/338 (50.59%), Query Frame = 2 Query: 1217 WNFNMEVWQDFSASVDDTSDISNINFKSNFLGTFSAKIFIAPNMIDFKNVFANFASLLANSXXXXXXXXXXXXXXXXXXXXMW--RKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVL-LEIKRDEK-FQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTGIISVLITYPCIFIASEIF 2218 W+ E W D V + + N L F + + N I+ FA+ N VV V L + L++ +W RKD ++ ++ L DNDP +Y Y+++V+TG R A TSS + + L G G + D +FE G V F+++T PLG+L +LR+WH++SG +PSW + ++++ D+ ++ + F+C +WLS + D ++V + ++D K F +LF +G D HI I + S +TRVQ+V+ ++ M+++ MF+G + A K+D G I TW + G+ S ++ +P + +IF Sbjct: 1285 WDEVQETWDDSGCQVGPRTSPYQTHCLCNHLTFFGSTFLVMSNAINIHQTAELFATFEDNPVVVTTVGCLCVVYVLVV---IWARRKDAQDQAKVKVTVLEDNDPFAQYHYLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADP-DTPVFERGAVDAFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDRKWYFLCNSWLSINVGDCVLDKVFPVATEQDRKQFSHLFFMKTSAGFQDGHIWYSIFSRCARSSFTRVQRVSCCFSLLLCTMLTSIMFWGVPKD---PAEQKMDLGKIEFTWQEVMIGLESSILMFPINLLIVQIF 1615 HSP 2 Score: 138.658 bits (348), Expect = 2.905e-31 Identity = 152/636 (23.90%), Postives = 271/636 (42.61%), Query Frame = 2 Query: 2288 LPKGFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPIILLIIFVLAKKLLGAVSTDQEANI----DEFVKDDLKKVLGANLN-------PPDQEKLEKIKKDKASGQRLSRVVGXXXXXXXXXXXXXXXXXXXRSQVTFDQTKMIRSRFIK--SNVQTYMDFYDWAQGILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISALVSKVYGNVPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTYAETIDENLFDYDKEMVD 4156 LP I VGW L+ + FFT LY L +G S +WL + V +F++ P+ +L +L V D+E + + D + A N PP +EK+K Q+ ++ + L Y+ L +L +AY R + + ++ F + S V + +F+ WA L N G I + G +IRQ+RV+ ++C + A + Y N C Y+L +ED + WN LS Q YQ+ GYP G +Y GGGY+ LG ++ + I+R L N WLD LTRA+F E TVYN N NLF + + E ++ G ++S RLY + G ++ +++Y L ++ + + K++ K+ YF S WNL+EL I S S + R ++ + ++ +SF + + ++ +S +++ + N ++++ + RA+ +S + + L+A+ N++F + L + ++ + + I Y ++ + P S L + F + ++FI ++ ++E + E+VD Sbjct: 1817 LPWWCILVGWLLVAATSGVAAFFTMLYGLHYGRASSLRWLISMAVSFVESMFVTQPLKVLGFAAFFALVLKRVD-DEEDTVAPLPGHLLGPDPYALFRARRNSSRDVYQPPLTAAIEKMKTTHLKEQKAFALIREILAYLGFLWMLLLVAYGQRDPSAYHLNRHLQHSFTRGFSGVLGFREFFKWANTTLVS----------NLYGHPPGFITDGNSKLVGSAQIRQVRVQESSCPL-AQQPQAYLNG-CRAPYSLDAEDMADYG---------------EGWNATTLSEWQ-------YQSQDQRQGYPIWGKLTVYRGGGYVVPLGTDRQSTSRILRYLFDNTWLDALTRAVFVESTVYNANVNLFCIVTLTLET-SALGTFFTHAALQSLRLYPFTDGWHPFVVAAELIYFLFLLYYMVVQGKRMSKETWGYFCSKWNLLELAIILASWSALAVFVKRAVLAERDLQRCRNHREEGISFSETAAADAALGYIIAFLVLLSTVKLWHLLRLNPKMNMITAALRRAWGDISGFMIVILTMLLAYSIASNLIFGWKLRSYKTLFDAAETMVSLQLGIFNYEEVLDYSPVLGSFLIGSC-IVFMTFVVLNLFISVILVAFSEEQKYYQLSEEGEIVD 2415
BLAST of PKD1L-2 vs. UniProt/SwissProt
Match: sp|Q7Z443|PK1L3_HUMAN (Polycystic kidney disease protein 1-like 3 OS=Homo sapiens OX=9606 GN=PKD1L3 PE=1 SV=1) HSP 1 Score: 135.961 bits (341), Expect = 1.485e-30 Identity = 86/338 (25.44%), Postives = 167/338 (49.41%), Query Frame = 2 Query: 1217 WNFNMEVWQDFSASVDDTSDISNINFKSNFLGTFSAKIFIAPNMIDFKNVFANFASLLANSXXXXXXXXXXXXXXXXXXXXMW--RKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVLLEIKRDE--KFQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTGIISVLITYPCIFIASEIF 2218 W + + W V S I N L F++ F+ P ++ ++ F + N V ++ L+ + + +W +KD+ + ++ L DNDP ++ Y+I V+TG R+A T++ + I L G G S + D + +FE G + F++TT + LG+L +LR+WH++SG+ PSW + ++++ D+ + + F+C WL+ D +RV + + + E F++LF M V ++ I + +TRVQ+++ +T+ MV N MF+ K N+ + + ++ ++ W + I + +I +P + +F Sbjct: 638 WEIHNQTWSSAGCQVGPQSTILRTQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITV---VWARKKDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKT-VFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQFTRVQRLSCCMTLLLCNMVINVMFW-KINSTTAKRDEQMR--PFAVAWSELLVSIHTAVILFPINLVIGRLF 968
BLAST of PKD1L-2 vs. UniProt/SwissProt
Match: sp|Q2EG98|PK1L3_MOUSE (Polycystic kidney disease protein 1-like 3 OS=Mus musculus OX=10090 GN=Pkd1l3 PE=1 SV=2) HSP 1 Score: 131.724 bits (330), Expect = 3.925e-29 Identity = 93/338 (27.51%), Postives = 158/338 (46.75%), Query Frame = 2 Query: 1217 WNFNMEVWQDFSASVDDTSDISNINFKSNFLGTFSAKIFIAPNMIDFKNVFANFASLLANSXXXXXXXXXXXXXXXXXXXXMW--RKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVLLEIKRDE--KFQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTGIISVLITYPCIFIASEIF 2218 W+ W+ V S I + L FS+ FI P +D +N LL + + V +L +L +++ MW RKDR + ++ L DNDP Y+I V+TG R A T++ + I L G G S + D + +FE G + F+++T S LGDL LR+WH++SG PSW + ++++ D+ T K + F C WL+ + +RV R E F++LF V ++ + + +TRVQ+++ + + MV N MF+ + ++ G +++T + I + +I +P I +F Sbjct: 1024 WDRYNRTWKSDGCQVGPKSTILKTQCLCDHLTFFSSDFFIVPRTVDVENTIK---LLLHVTNNPVGVSLLSSLLGFYILLAMWASRKDREDMQKVKVTVLADNDPSSASHYLIQVYTGYRRRAATTAKVVITLYGSEGHSEPHHLCDPEKT-VFERGALDVFLLSTGSWLGDLHGLRLWHDNSGDSPSWYVSQVIVSDMTTRKKWHFQCNCWLAVDLGNCERDRVFTPASRSELSSFRHLFSSTIVEKFTQDYLWLSVATRHPWNQFTRVQRLSCCMALLLCDMVINIMFWKMGGTTAKRGTEQL--GPLAVTLSELLVSIQTSIILFPIHLIFGRLF 1355 HSP 2 Score: 117.857 bits (294), Expect = 6.000e-25 Identity = 148/607 (24.38%), Postives = 262/607 (43.16%), Query Frame = 2 Query: 2261 EAKMKKMFLLPKGFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPI---ILLIIFVLAKKLLGAVSTDQEANIDEFVKDDLKKVLGA-----NLNP----PDQEKLEKIKKDKASGQRLSRVVGXXXXXXXXXXXXXXXXXXXRSQVTFDQTKMIRSRFIK--SNVQTYMDFYDWAQGILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISALVSKVYGNVPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNM-IVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFI--CFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSAL 4030 E K F L + W LL V +AS FF LYSL+ +++ W+ + + + +F+S PI L ++F L + ++ D+E + V K A NP P L K + KA ++LS++ G L +L L LL Y A+ F + I RF S ++T DFY WA G L P ++ GD I + G IRQ R+ N + K + P ++ ED ++ W P +++++ DS W+ YQN GGYP +G Y GGGY+ LG A ++++L+ WLD T+A+F E TV+N N NL + ++ E S G+ F ++ L ++ Q++Y L V + + ++ +Q+ +F+ NL++ + +S SI+ + + + + + ++ ++SF +A L G + +RV + + + ++ T+ +A+ ++ LGF+ I L ++ N+LF + + + S V++ G+ + K+ ++ P S L Sbjct: 1527 EGKKPMSFCLFRWLKCSCWLLLGVISLASAFFITLYSLELDKDQATSWVISMMLSVLQDIFISQPIKVIFLTLLFSLMANHMPWLNKDKEQHARRIVALWAKCPWSAPGLRDKNNPIYTAPAMNNLAKPTR-KAWKKQLSKLTGGTLVQILFLTLLMTTVYSAKDSSRFFLHRAIWKRFSHRFSEIKTVEDFYPWANGTL---LPNLY-------GDYRGFITDGNSFLLGNVLIRQTRIP-NDIFFPGSLHKQMKSPPQHQ------EDRENYGAGWVP-PDTNITKVDSIWH---------------YQNQESLGGYPIQGELATYSGGGYVVRLGRNHSAATRVLQHLEQRRWLDHCTKALFVEFTVFNANVNLLCAVTLILE---SSGVGTFLTSLQLDSLTSLQSSERGFAWIVSQVVYYLLVCYYAFIQGCRLKRQRLAFFTRKRNLLDTSIVLISFSILGLSMQSLSLLHKKMQQYHCDRDRFISFYEALRVNSAVTHLRGFLLLFATVRVWDLLRHHAQLQVINKTLSKAWDEV--LGFILIIVVLLSSYAMTFNLLFGWSISDYQSFFRSIVTVVGLLMGTSKHKEVIALYPILGSLL 2094
BLAST of PKD1L-2 vs. UniProt/SwissProt
Match: sp|Q6IVV8|PKD2_DANRE (Polycystin-2 OS=Danio rerio OX=7955 GN=pkd2 PE=1 SV=1) HSP 1 Score: 123.25 bits (308), Expect = 6.565e-27 Identity = 116/496 (23.39%), Postives = 224/496 (45.16%), Query Frame = 2 Query: 2771 NVQTYMDFYDWAQG-ILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISA-LVSKVYGNVPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTYAET-IDENLFDYDKEMVDHVWNIFNEMMT--GFKSSMKYTVPDALKKKA 4243 ++ T DF+ + +G LN Y ++WYNN ++ ++ + L G R+RQ+RV+ +C++ L +VY C Y+ +ED F K N + W + + +++ Q +T GG ++ L +E++A ++ L+ N WLD+ TRA+F + ++YNGN NLF +++L E P +GG + + ++ RL Y+ + + ++ + L V+ + E ++ + YF S WN +++L + LS+ II R + + L N Y +F+ L I F+S +++ K++ FNK ++ + T+ R L MF +A+ + ++F F+ + F + + + ++ E +Y+ + + ++F+ I+NDTY+E D + E+ D + +N M K S +PD+L++ A Sbjct: 208 SLSTMEDFWKFTEGPFLNGMYWELWYNN--KSLPENQSLIYYENLLLGVPRLRQLRVRNESCSVHEDLRDEVYD---CYNVYSPANEDKAPFGPK-----------NGTAWR--FKDESSLGESSYWGQVSTYGGGGYYQ-------------DLSRTREKSANQLQELKNNLWLDRGTRAVFLDFSIYNGNVNLFCIVRLLVEFPATGGA-VPSWQFQTVRLLRYVSSWDYFVGMCEVSFCLFVLYYLVEEALEIRLHRLRYFKSLWNCLDVLIVALSVPAIIMNICRTSAVSHRLHFLLENHSTYPNFEPLARLQVHFNNLAAIIVFLSWVKLFKFINFNKTMNQLSTTMSRCAKDLMGFAIMFFIVFLAYAQLAYLVFGTQVNDFSTFQACIFTQFRIILGDFDFSEIEEADSVL-GPIYFTTFVFFIFMILLNMFLAIINDTYSEVKADMAQQRSEMEITDLIKKSYNRAMVKLKLKKSSINDIPDSLQQAA 670
BLAST of PKD1L-2 vs. TrEMBL
Match: A0A0H3YFF8 (PKD1L-2 OS=Schmidtea mediterranea OX=79327 GN=PKD1L-2 PE=2 SV=1) HSP 1 Score: 2262.65 bits (5862), Expect = 0.000e+0 Identity = 1180/1191 (99.08%), Postives = 1185/1191 (99.50%), Query Frame = 2 Query: 1055 STSWDTSSGMLRITIPSGQVTPPNNMTLVMITSTNTTNGILLLSLGVASLTPRIWNFNMEVWQDFSASVDDTSDISNINFKSNFLGTFSAKIFIAPNMIDFKNVFANFASLLANSXXXXXXXXXXXXXXXXXXXXMWRKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVLLEIKRDEKFQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTGIISVLITYPCIFIASEIFXXXXXXXXXXXEDQEAKMKKMFLLPKGFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPIILLIIFVLAKKLLGAVSTDQEANIDEFVKDDLKKVLGANLNPPDQEKLEKIKKDKASGQRLSRVVGXXXXXXXXXXXXXXXXXXXRSQVTFDQTKMIRSRFIKSNVQTYMDFYDWAQGILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISALVSKVYGNVPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTYAETIDENLFDYDKEMVDHVWNIFNEMMTGFKSSMKYTVPDALKKKAIVPVDMSDVDMQFASKENIRNMVSKRVNPSLRRKLADLNGEKYKTEKRENKPNSENDVYINPISFTDIKVAATGSQILDDKTFAERLPKYRAKQNAVDTNNQPPSYMEPVRPLKPNPKIDLFSKTERK 4627 S SWDTSSGMLRITIPSGQVTPPNNMTLVMITSTNTTNGILLLSLGVASLTPRIWNF+MEVWQDFSASVDDTSDISNINFKSNFLGTFSAKIFIAPNMIDFKNVFANFASLLANSYVVLIVIILIFILYLLLVIVMWRKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVLLEIKRDEKFQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTG+ISVLITYPCIFIASEIFRRTRRWKRRWTEDQEAKMKKMFLLPKGFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPIILLIIFVLAKKLLGAVSTDQEANIDEFVKDDLKKVLGANLNPPDQEKLEKIKKDKASGQRLSRVVGDALTYVLSLLLLTALAYDARSQVTFDQTKMIRSRFIKSNVQTYMDFYDWAQGILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCT+SALVSKVYGNVPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFGIYGGGGYIASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVELLSIFLSLSIIICTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTYAETIDENLFDYDKEMVDHVWNIFNEMMTGFKSSMKYTVPDALKKKAIVPVDMSDVDMQFASKENIRNMVSKRVNPSLRRKLADLNGEKYKTEKRENKPNSENDVYINPISFTDIKVAATGSQILDDKTFAERLPKYRAKQNAVDTNNQPPSYMEPVRPLKPNPKID + +K Sbjct: 613 SASWDTSSGMLRITIPSGQVTPPNNMTLVMITSTNTTNGILLLSLGVASLTPRIWNFDMEVWQDFSASVDDTSDISNINFKSNFLGTFSAKIFIAPNMIDFKNVFANFASLLANSYVVLIVIILIFILYLLLVIVMWRKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVLLEIKRDEKFQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTGMISVLITYPCIFIASEIFRRTRRWKRRWTEDQEAKMKKMFLLPKGFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPIILLIIFVLAKKLLGAVSTDQEANIDEFVKDDLKKVLGANLNPPDQEKLEKIKKDKASGQRLSRVVGDALTYVLSLLLLTALAYDARSQVTFDQTKMIRSRFIKSNVQTYMDFYDWAQGILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTVSALVSKVYGNVPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFGIYGGGGYIASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVELLSIFLSLSIIICTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTYAETIDENLFDYDKEMVDHVWNIFNEMMTGFKSSMKYTVPDALKKKAIVPVDMSDVDMQFASKENIRNMVSKRVNPSLRRKLADLNGEKYKTEKRENKPNSENDVYINPISFTDIKVAATGSQILDDKTFAERLPKYRAKQNAVDTNNQPPSYMEPVRPLKPNPKIDYILQNRKK 1803 HSP 2 Score: 541.576 bits (1394), Expect = 9.183e-160 Identity = 326/327 (99.69%), Postives = 327/327 (100.00%), Query Frame = 3 Query: 81 IMQRSRLCNNPAPSNAGQDCSGLSTDTQSCTNVPLNCPVNGMXXXXXXXXXXXXXXXXXXXXXXXNCDNPSPLNGGLGCSSCVTVIFGSCGMSDINVENCTWISCSDPQLVAQNIISDTLSKLNISGTNSTMSVQQTMNLAFDVVNKIQSALQNALLNSTGPLMIQTNEVTVGLQSLSPTSGQQNISMVSTDKGKISIGSSLNLTTPTVVTXXXXXXXXXXXXXXXXXXXXXMLSLTIQNVSNTTPVQLSVSIPNSNQQVESDMLSPVKFNVSNQLIQTLQYTSLSTVYKLSMNLSNATDFTIFFSASSLANTTDSSDAFIYLSNQL 1061 IMQRSRLCNNPAPSNAGQDCSGLSTDTQSCTNVPLNCPVNGMWSSWSTWSSCSSSCGFGTRSRTRNCDNPSPLNGGLGCSSCVTVIFGSCGMSDINVENCTWISCSDPQLVAQNIISDTLSKLNISGTNSTMSVQQTMNLAFDVVNKIQSALQNALLNSTGPLMIQTNEVTVGLQSLSPTSGQQNISMVSTDKGKISIGSSLNLTTPTVVTFSALKSSVFFSASSVADTSAAMLSLTIQNVSNTTPVQLSVSIPNSNQQVESDMLSPVKFNVSNQLIQTLQYTSLSTVYKLSMNLSNATDFTIFFSASSLANTTDSSDAFIYLSNQ+ Sbjct: 276 IMQRSRLCNNPAPSNAGQDCSGLSTDTQSCTNVPLNCPVNGMWSSWSTWSSCSSSCGFGTRSRTRNCDNPSPLNGGLGCSSCVTVIFGSCGMSDINVENCTWISCSDPQLVAQNIISDTLSKLNISGTNSTMSVQQTMNLAFDVVNKIQSALQNALLNSTGPLMIQTNEVTVGLQSLSPTSGQQNISMVSTDKGKISIGSSLNLTTPTVVTFSALKSSVFFSASSVADTSAAMLSLTIQNVSNTTPVQLSVSIPNSNQQVESDMLSPVKFNVSNQLIQTLQYTSLSTVYKLSMNLSNATDFTIFFSASSLANTTDSSDAFIYLSNQV 602
BLAST of PKD1L-2 vs. TrEMBL
Match: A0A267G7R4 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig019064g1 PE=4 SV=1) HSP 1 Score: 829.321 bits (2141), Expect = 0.000e+0 Identity = 479/1132 (42.31%), Postives = 712/1132 (62.90%), Query Frame = 2 Query: 1085 LRITIPSGQVTP----------PNNMTLVMITSTNTT--NGILLLSLGVASLTPRIWNFNMEVWQDFSASVDDTSDISNINFKSNFLGTFSAKIFIAPNMIDFKNVFANFASLLANSXXXXXXXXXXXXXXXXXXXXMWRKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVLLEIKRDEKFQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTGIISVLITYPCIFIASEIFXXXXXXXXXXXEDQEAKMKKMFLLPKGFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPIILLIIFVLAKKLLGAVSTDQEA-NIDEFVKDDLKKVL-GANLNPPDQEKLEKIKKDKASGQRLSRVVGXXXXXXXXXXXXXXXXXXXRSQVTFDQTKMIRSRFIKSNVQTYMDF---YDWAQG-ILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISALVSKVYGNVP--CNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNY------------LSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSAL-YYNVWSALSVFFITSVFICILNDTYAETIDENLFDYDKEMVDHVWNIFNEMMTGFKSSMKYTVPDALKKKAIVP----VDMSDVDMQF----------ASKENIRNMVSKRVNPSLR 4339 L + IP GQ+ +N T + +N T + + L++GVAS+TPR W+ + W D A V + S I + FKSNF G++S K+FIAPN I+F VF NFA LA ++V L+V+ LI +Y+++ + MWR DR+E+ LRYEPL DN+ + +Y+++ISV+TG A T+S++FINL G WGSSG R+++DG R F G+VCNF MTT +PLG+L L++WH++SG KP W LEK++IED+QT K Y+FMC+ WL+++KFD T RVL E+K+D++FQ + R K GV++KH+I + TG S Y+R+Q+ V MFFL MV NAM++GK ++L +ANF ID G IS+TWFQ Y+GI+S+ ITYPCIF A+EIFRRT++W+RRW+ED KK LPKGF+ +GW LL + + S FFTFLYS++WG EK+N WL++FF+GI +V ++DPI LLI+FV+AKK+ G +++ +D+ + DDLK+VL G PPD ++E+I+ ++ + Q++S+ D ++YV+ + LL ALAYD+R QV+F Q + ++ +F+ + + DF +DW G I+ Y YN TGDL AI CDC++QGPFR+RQ+RV C ++ K Y C+ +++ + D + W P +N W RN + P + V+ AF Y++ +PFEG F Y G GY A+LG+ +A +II L+A NWLD+ TRA+F EGTVYN NTNLFTTIQ+L E P +GG+ + GVR+YRLY+Y G I+L+ MQ L+AL + IYRE + + + +YF WN +E ++I L ++I+I +RI +TI++I ++ N+G YV+FD W+E +C+ M +S F++I RVLK++GFNK+I+I+ T+ + QLSS G F+ + AFL+ G ILFS F ++L+S SLF + I Y +F ++L ++ WS L+VFF+ SVF+ IL DTY+ + + L+ YD+E V+H+W+ F M +S K + +AL+K V D+++Q ++E+ +K +NP R Sbjct: 1027 LSVFIPGGQMAAGSAVFMSLELADNGTAAAASGSNVTTESANMSLTVGVASITPRAWSDLLGGWVDTDAEVAEESSIEKMVFKSNFFGSYSGKMFIAPNTINFATVFNNFAGKLAENFVTLLVLCLIIGIYVVVSVWMWRLDRQEAANLRYEPLEDNEFDNDYTFIISVYTGDESGADTTSNVFINLAGTWGSSGKRQLSDGVRQN-FSRGSVCNFAMTTRAPLGELRGLKVWHDNSGKKPGWFLEKILIEDLQTKKNYVFMCDQWLAENKFDSRTMRVLPEVKQDQRFQEMMLRYKAGGVVNKHVITALFRKTGQSNYSRLQRTGVANAMFFLTMVCNAMWYGKGDDLDAEANFSIDLGPISVTWFQLYSGILSMAITYPCIFAAAEIFRRTKKWQRRWSEDDVESKKKEIRLPKGFLVIGWGLLLLGVGLSFFFTFLYSIEWGKEKANGWLKSFFLGILQLVVVTDPICLLIVFVVAKKIFGQKESEENVFELDDLINDDLKQVLDGTEYAPPDPTRMEEIRAERRNNQKMSQTFTDVMSYVVYMFLLVALAYDSRDQVSFRQNQNLKDQFLTAAPTRFNDFKHVFDWLNGSIVPRLYRTTEYNGEPLTGDLKDAIDTCDCIKQGPFRLRQLRVNPRKCPVTWPF-KAYPQKSWICSSDFSPQAADQAVYRPLWLPDSN--------GWVRNASLQMRAKSQIKRMRPDEIVLQAFWYRSADSMMSFPFEGAFTTYPGDGYAATLGLNSAEAMWIINRLRATNWLDEKTRAMFLEGTVYNANTNLFTTIQILLEFPAAGGILTYKNGVRTYRLYNYTGGKGIILMAMQGLFALICLYQIYRETRSLLTLRLKYFDDLWNKIEFVNILLCITIMITYGIRIKITIDSIELMMNNRGMYVAFDNVIEWVEATCVAMALSVFLTIFRVLKFLGFNKHIAILLATVKQCARQLSSFGVAFVLIMAAFLSAGTILFSFTEASFASVLSSCRSLFTTALGIQGYTQIFVNSQGTTASLIFFGGWSCLAVFFLVSVFVSILTDTYSVVVSDGLYSYDEEFVNHMWSKFMGTMASI-TSKKDELGEALQKSVSAVKRRMVTEDDIEIQLNEDRRQESVGGAEESSGGKKAKDINPGSR 2147
BLAST of PKD1L-2 vs. TrEMBL
Match: A0A1I8J395 (PKD_channel domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 625.55 bits (1612), Expect = 0.000e+0 Identity = 365/877 (41.62%), Postives = 549/877 (62.60%), Query Frame = 2 Query: 1832 MCETWLSDSKFDGNTERVLLEIKRDEKFQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTGIISVLITYPCIFIASEIFXXXXXXXXXXXEDQEAKMKKMFLLPKGFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPIILLIIFVLAKKLLGAVSTDQEA-NIDEFVKDDLKKVL-GANLNPPDQEKLEKIKKDKASGQRLSRVVGXXXXXXXXXXXXXXXXXXXRSQVTFDQTKMIRSRFIKSNVQTYMDF---YDWAQG-ILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISALVSKVYGNVP--CNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNR-----NYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSAL-YYNVWSALSVFFITSVFICILNDTYAETIDENLFDYDKEMVDHVWNIFNEMMTGFKSSMKYTVPDALKKKAIVP----VDMSDVDMQF----------ASKENIRNMVSKRVNPSLRRKLADLNGEKYKT 4378 MC+ WL+++KFD T RVL E+K+D++FQ + R K GV++KH+I + TG S Y+R+Q+ V MFFL MV NAM++GK ++L +ANF ID G IS+TWFQ Y+GI+S+ ITYPCIF A+EIFRRT++W+RRW+ED KK LPKGF+ +GW LL + + S FFTFLYS++WG EK+N WL++FF+GI +V ++DPI LLI+FV+AKK+ G +++ +D+ + DDLK+VL G PPD ++E+I+ ++ + Q++S+ D ++YV+ + LL ALAYD+R QV+F Q + ++ +F+ + + DF +DW G I+ Y YN TGDL AI CDC++QGPFR+RQ+RV C ++ K Y C+ +++ + D + W P +N V N S R + P + V+ AF Y++ +PFEG F Y G GY A+LG+ +A +II L+A NWLD+ TRA+F EGTVYN NTNLFTTIQ+L E P +GG+ + GVR+YRLY+Y G I+L+ MQ L+AL + IYRE + + + +YF WN +E ++I L ++I+I +RI +TI++I ++ N+G YV+FD W+E +C+ M +S F++I RVLK++GFNK+I+I+ T+ + QLSS G F+ + AFL+ G ILFS F ++L+S SLF + I Y +F ++L ++ WS L+VFF+ SVF+ IL DTY+ + + L+ YD+E V+H+W+ F M +S K + +AL+K V D+++Q ++E+ +K +NP L+ KLA +N +K +T Sbjct: 1 MCDQWLAENKFDSRTMRVLPEVKQDQRFQEMMLRYKAGGVVNKHVITALFRKTGQSNYSRLQRTGVANAMFFLTMVCNAMWYGKGDDLDAEANFSIDLGPISVTWFQLYSGILSMAITYPCIFAAAEIFRRTKKWQRRWSEDDVESKKKEIRLPKGFLVIGWGLLLLGVGLSFFFTFLYSIEWGKEKANGWLKSFFLGILQLVVVTDPICLLIVFVVAKKIFGQKESEENVFELDDLINDDLKQVLDGTEYAPPDPTRMEEIRAERRNNQKMSQTFTDVMSYVVYMFLLVALAYDSRDQVSFRQNQNLKDQFLTAAPTRFNDFKHVFDWLNGSIVPRLYRTTEYNGEPLTGDLKDAIDTCDCIKQGPFRLRQLRVNPRKCPVTWPF-KAYPQKSWICSSDFSPQAADQAVYRPLWLPDSNGWVR-NASLQMRAKSQIKRMRPDEIVLQAFWYRSADSMMSFPFEGAFTTYPGDGYAATLGLNSAEAMWIINRLRATNWLDEKTRAMFLEGTVYNANTNLFTTIQILLEFPAAGGILTYKNGVRTYRLYNYTGGKGIILMAMQGLFALICLYQIYRETRSLLTLRLKYFDDLWNKIEFVNILLCITIMITYGIRIKITIDSIELMMNNRGMYVAFDNVIEWVEATCVAMALSVFLTIFRVLKFLGFNKHIAILLATVKQCARQLSSFGVAFVLIMAAFLSAGTILFSFTEASFASVLSSCRSLFTTALGIQGYTQIFVNSQGTTASLIFFGGWSCLAVFFLVSVFVSILTDTYSVVVSDGLYSYDEEFVNHMWSKFMGTMASI-TSKKDELGEALQKSVSAVKRRMVTEDDIEIQLNEDRRQESVGGAEESSGGKKAKDINPGLKMKLAVVNRDKPET 874
BLAST of PKD1L-2 vs. TrEMBL
Match: A0A1I8FWM9 (PKD_channel domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 625.55 bits (1612), Expect = 0.000e+0 Identity = 376/939 (40.04%), Postives = 568/939 (60.49%), Query Frame = 2 Query: 1832 MCETWLSDSKFDGNTERVLLEIKRDEKFQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTGIISVLITYPCIFIASEIFXXXXXXXXXXXEDQEAKMKKMFLLPKGFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPIILLIIFVLAKKLLGAVSTDQEA-NIDEFVKDDLKKVL-GANLNPPDQEKLEKIKKDKASGQRLSRVVGXXXXXXXXXXXXXXXXXXXRSQVTFDQTKMIRSRFIKSNVQTYMDF---YDWAQG-ILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISALVSKVYGNVP--CNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNR-----NYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSAL-YYNVWSALSVFFITSVFICILNDTYAETIDENLFDYDKEMVDHVWNIFNEMMTGFKSSMKYTVPDALKKKAIVP----VDMSDVDMQF----------ASKENIRNMVSKRVNPSLRRKLADLNGEKYKTEKRENKPNSENDVYINPISFTDIKVAATG--SQILDDKTFAERLPKYRAKQNAVDTNNQPPS 4558 MC+ WL+++KFD T RVL E+K+D++FQ + R K GV++KH+I + TG S Y+R+Q+ V MFFL MV NAM++GK ++L +ANF ID G IS+TWFQ Y+GI+S+ ITYPCIF A+EIFRRT++W+RRW+ED KK LPKGF+ +GW LL + + S FFTFLYS++WG EK+N WL++FF+GI +V ++DPI LLI+FV+AKK+ G +++ +D+ + DDLK+VL G PPD ++E+I+ ++ + Q++S+ D ++YV+ + LL ALAYD+R QV+F Q + ++ +F+ + + DF +DW G I+ Y YN TGDL AI CDC++QGPFR+RQ+RV C ++ K Y C+ +++ + D + W P +N V N S R + P + V+ AF Y++ +PFEG F Y G GY A+LG+ +A +II L+A NWLD+ TRA+F EGTVYN NTNLFTTIQ+L E P +GG+ + GVR+YRLY+Y G I+L+ MQ L+AL + IYRE + + + +YF WN +E ++I L ++I+I +RI +TI++I ++ N+G YV+FD W+E +C+ M +S F++I RVLK++GFNK+I+I+ T+ + QLSS G F+ + AFL+ G ILFS F ++L+S SLF + I Y +F ++L ++ WS L+VFF+ SVF+ IL DTY+ + + L+ YD+E V+H+W+ F M +S K + +AL+K V D+++Q ++E+ +K +NP L+ KLA +N +KP + P D + G S + + + +P++ K A+D QPP Sbjct: 1 MCDQWLAENKFDSRTMRVLPEVKQDQRFQEMMLRYKAGGVVNKHVITALFRKTGQSNYSRLQRTGVANAMFFLTMVCNAMWYGKGDDLDAEANFSIDLGPISVTWFQLYSGILSMAITYPCIFAAAEIFRRTKKWQRRWSEDDVESKKKEIRLPKGFLVIGWGLLLLGVGLSFFFTFLYSIEWGKEKANGWLKSFFLGILQLVVVTDPICLLIVFVVAKKIFGQKESEENVFELDDLINDDLKQVLDGTEYAPPDPTRMEEIRAERRNNQKMSQTFTDVMSYVVYMFLLVALAYDSRDQVSFRQNQNLKDQFLTAAPTRFNDFKHVFDWLNGSIVPRLYRTTEYNGEPLTGDLKDAIDTCDCIKQGPFRLRQLRVNPRKCPVTWPF-KAYPQKSWICSSDFSPQAADQAVYRPLWLPDSNGWVR-NASLQMRAKSQIKRMRPDEIVLQAFWYRSADSMMSFPFEGAFTTYPGDGYAATLGLNSAEAMWIINRLRATNWLDEKTRAMFLEGTVYNANTNLFTTIQILLEFPAAGGILTYKNGVRTYRLYNYTGGKGIILMAMQGLFALICLYQIYRETRSLLTLRLKYFDDLWNKIEFVNILLCITIMITYGIRIKITIDSIELMMNNRGMYVAFDNVIEWVEATCVAMALSVFLTIFRVLKFLGFNKHIAILLATVKQCAHQLSSFGVAFVLIMAAFLSAGTILFSFTEASFASVLSSCRSLFTTALGIQGYTQIFVNSQGTTASLIFFGGWSCLAVFFLVSVFVSILTDTYSVVVSDGLYSYDEEFVNHMWSKFMGTMASI-TSKKDELGEALQKSVSAVKRRMVTEDDIEIQLNEDRRQESVGGAEESSGGKKAKDINPGLKMKLAVVN---------RDKPETGESYVWTPKETGDEVLVDAGELSAVATEDAEPDWIPRF--KSTALDL--QPPG 923
BLAST of PKD1L-2 vs. TrEMBL
Match: A0A1I8FX52 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 589.341 bits (1518), Expect = 0.000e+0 Identity = 354/877 (40.36%), Postives = 537/877 (61.23%), Query Frame = 2 Query: 1832 MCETWLSDSKFDGNTERVLLEIKRDEKFQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTGIISVLITYPCIFIASEIFXXXXXXXXXXXEDQEAKMKKMFLLPKGFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPIILLIIFVLAKKLLGAVSTDQEA-NIDEFVKDDLKKVL-GANLNPPDQEKLEKIKKDKASGQRLSRVVGXXXXXXXXXXXXXXXXXXXRSQVTFDQTKMIRSRFIKSNVQTYMDF---YDWAQG-ILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISALVSKVYGNVP--CNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNR-----NYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSAL-YYNVWSALSVFFITSVFICILNDTYAETIDENLFDYDKEMVDHVWNIFNEMMTGFKSSMKYTVPDALKKKAIVP----VDMSDVDMQF----------ASKENIRNMVSKRVNPSLRRKLADLNGEKYKT 4378 MC+ WL+++KFD T RVL E+K+D++FQ + R K GV++KH+I + TG S Y+R+Q+ V MFFL MV NAM++GK ++L +ANF ID G IS+TWFQ Y+GI+S+ ITYPCIF A+EIFRRT++W+RRW+ED KK LPKGF+ +GW LL + + S FFTFLYS++WG EK+N WL++FF+GI +V ++DPI LLI+FV+AKK+ G +++ +D+ + DDLK+VL G PPD ++E+I+ ++ + Q++S+ D ++YV+ + LL ALAYD+R QV+F Q + ++ +F+ + + DF +DW G I+ Y YN TGDL AI CDC++QGPFR+RQ+RV C ++ K Y C+ +++ + D + W P +N V N S R + P + V+ AF Y++ +PFEG F Y G GY A+LG + ++R ++F EGTVYN NTNLFTTIQ+L E P +GG+ + GVR+YRLY+Y G I+L+ MQ L+AL + IYRE + + + +YF WN +E ++I L ++I+I +RI +TI++I ++ N+G YV+FD W+E +C+ M +S F++I RVLK++GFNK+I+I+ T+ + QLSS G F+ + AFL+ G ILFS F ++L+S SLF + I Y +F ++L ++ WS L+VFF+ SVF+ IL DTY+ + + L+ YD+E V+H+W+ F M +S K + +AL+K V D+++Q ++E+ +K +NP L+ KLA +N +K +T Sbjct: 1 MCDQWLAENKFDSRTMRVLPEVKQDQRFQEMMLRYKAGGVVNKHVITALFRKTGQSNYSRLQRTGVANAMFFLTMVCNAMWYGKGDDLDAEANFSIDLGPISVTWFQLYSGILSMAITYPCIFAAAEIFRRTKKWQRRWSEDDVESKKKEIRLPKGFLVIGWGLLLLGVGLSFFFTFLYSIEWGKEKANGWLKSFFLGILQLVVVTDPICLLIVFVVAKKIFGQKESEENVFELDDLINDDLKQVLDGTEYAPPDPTRMEEIRAERRNNQKMSQTFTDVMSYVVYMFLLVALAYDSRDQVSFRQNQNLKDQFLTAAPTRFNDFKHVFDWLNGSIVPRLYRTTEYNGEPLTGDLKDAIDTCDCIKQGPFRLRQLRVNPRKCPVTWPF-KAYPQKSWICSSDFSPQAADQAVYRPLWLPDSNGWVR-NASLQMRAKSQIKRMRPDEIVLQAFWYRSADSMMSFPFEGAFTTYPGDGYAATLG------STVLRP------------SMFLEGTVYNANTNLFTTIQILLEFPAAGGILTYKNGVRTYRLYNYTGGKGIILMAMQGLFALICLYQIYRETRSLLTLRLKYFDDLWNKIEFVNILLCITIMITYGIRIKITIDSIELMMNNRGMYVAFDNVIEWVEATCVAMALSVFLTIFRVLKFLGFNKHIAILLATVKQCARQLSSFGVAFVLIMAAFLSAGTILFSFTEASFASVLSSCRSLFTTALGIQGYTQIFVNSQGTTASLIFFGGWSCLAVFFLVSVFVSILTDTYSVVVSDGLYSYDEEFVNHMWSKFMGTMASI-TSKKDELGEALQKSVSAVKRRMVTEDDIEIQLNEDRRQESVGGAEESSGGKKAKDINPGLKMKLAVVNRDKPET 856
BLAST of PKD1L-2 vs. Ensembl Cavefish
Match: pkd1l2a (polycystin 1 like 2 [Source:NCBI gene;Acc:103044173]) HSP 1 Score: 158.688 bits (400), Expect = 2.590e-38 Identity = 102/340 (30.00%), Postives = 172/340 (50.59%), Query Frame = 2 Query: 1211 RIWNFNMEVWQDFSASVDDTSDISNINFKSNFLGTFSAKIFIAPNMIDFKNVFANFASLLANSXXXXXXXXXXXXXXXXXXXXMW--RKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVL-LEIKRD-EKFQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTGIISVLITYPCIFIASEIF 2218 + W+ W D+ V + L F + F+ PN++D FA+ + N VV V + L++ +W RKD +++ L+ L DNDP EY Y+++V TG A TSS + + +LG G S +TD ++ +FE G V F++TT LGDL ++R+WH++SG P+W + K++++D++T + + F+C +WL+ + ++V + + D ++F NLF D HI + + S +TRVQ+V+ ++ M++N MF+G + S +D G I TW Q GI S +I +P + IF Sbjct: 1411 KYWDETKTNWSDYGCRVGPRTTPQLTQCLCTHLTFFGSSFFVMPNLVDVSRTAELFATFVNNPVVVCFVGAIFLAYLLVV---IWARRKDIQDTAKLKLTVLQDNDPLAEYRYLVTVTTGHRLGASTSSQVTVTILGSEGESEPHHLTDPHKP-VFERGAVDMFLLTTPFSLGDLQSIRLWHDNSGTHPAWFVNKVMVQDLETGQKWHFLCSSWLAIDVGECTLDKVFPVATEMDLKQFSNLFFMKTAKDFRDGHIWFSVISRPPSSNFTRVQRVSCCFSLLLCTMLTNIMFWGIPTDPSEQT---MDLGKIEFTWQQVMIGIQSSIIMFPINLLIVSIF 1743 HSP 2 Score: 157.147 bits (396), Expect = 8.662e-38 Identity = 161/639 (25.20%), Postives = 288/639 (45.07%), Query Frame = 2 Query: 2288 LPKGFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPIILLIIFVLAKKLLGAVSTDQEANIDEFV------KDDLKKVLGANLN-------PPDQEKLEKIKKDKASGQRLSRVVGXXXXXXXXXXXXXXXXXXXRSQVTFDQTKMIRSRFIK--SNVQTYMDFYDWAQGILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISALVSKVYGNVP-CNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTYAETIDENLFDYDKEMVD 4156 LP F+FVGW L+ S +FT +Y L +G +KS WL + V F +F++ P+ +L V +L V DQE D + DD V A + PP +EK++ + Q++ ++ + L Y+ L +L +AY R F T+ I+ F S+ T+ + + WA L NN+ G I + G R+RQ+RV+ +C + + +VP C+ Y+ ED S+ W P D+N ++ +P Q YQ + +P G +Y GGG++ LG +E A+ ++ L N WLD TRAIF E TVYN N NLF + ++FE G + + ++S RLY G I ++ +++Y L + ++++ K + +QK EYF S WNL+++ I LS S + R ++ +I +K Y F++ + ++ ++ +++ + N + ++ T+ RA+ +S + +A+ N+L+ + LL + ++ + + I Y ++ + P A F + ++FI ++ ++E + ++E+VD Sbjct: 1958 LPWWFVFVGWFLVAATSGVSAYFTMMYGLTYGKQKSISWLISMLVSFFESLFITQPVKVLGFAVFFALVLKKV--DQEEYGDVPIDGNLPNSDDPDAVRFARRDSTCSFYQPPPPSNIEKMRNNMIKEQKVFGLIREILIYMGFLWMLLLVAYGQRDPNAFYLTQHIQQSFSNGISDSMTHGEVFQWANSTL--------LNNL--FGQQPGFITDGNSKLVGNARLRQVRVQDGSCRVD---RSMRNSVPDCHAPYSWDMEDLGSYGPGWNPSI-------DANLSKTLPTPWQ-------YQTQSRLRAHPIWGGVAVYRGGGFVVDLGPNRENASSSLQYLFENTWLDMFTRAIFVEFTVYNANVNLFCIVTLMFETTAVGAFQ-YRSELQSVRLYQSTGGLHIFVMASEVVYFLFIFYYMFQQGKLMKQQKWEYFRSKWNLLDMAIIILSWSALPVFIKRTLLGNQSIEYYQNHKDEYAGFNETATADAVLGYIIAFLVLLATVKLWHLLRLNPKLHMITSTLQRAWNDISGFIVVMTIMFLAYSVACNLLYGWKLYSYRTLLNAAQTIVSLQLGIFNYEEVLDYNPVL-GAFIVGSCIIFMTFVVLNLFISVILVAFSEEQIHHKPSEEEEIVD 2565
BLAST of PKD1L-2 vs. Ensembl Cavefish
Match: ENSAMXT00000006495.2 (pep primary_assembly:Astyanax_mexicanus-2.0:5:35007331:35041448:1 gene:ENSAMXG00000006274.2 transcript:ENSAMXT00000006495.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 141.354 bits (355), Expect = 4.200e-33 Identity = 99/359 (27.58%), Postives = 179/359 (49.86%), Query Frame = 2 Query: 1157 NTTNGILLLSLGVASLTPRIWNFNMEVWQDFSASVDDTSDISNINFKSNFLGTFSAKIFIAPNMIDFKNVFANFASLLANSXXXXXXXXXXXXXXXXXXXXMW--RKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGK-WGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVL-LEIKRD-EKFQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTGIISVLITYPCIFIASEIF 2218 N++N +++S A + W+ W D+ V + L F + F+ PN +D FA+ N VV V + + ++ + +W RKD ++ + ++ L DNDP EY Y++ + TG R A TSS + + + G W S H +TD + +FE G V F+++T LGDL ++R+WH++SG P+W + K++++D++ + + F+C +WL+ + ++V L + D ++F NLF + D H+ + + S +TRVQ+V+ ++ M++ MF+G ++ S + + G I +W Q GI S +I +P + IF Sbjct: 531 NSSNASVIISSIAAQC--KYWDNIKTNWSDYGCRVGPGTTRLVTQCLCTHLTFFGSSFFVMPNAVDVTRTAELFATFSQNPVVVCFVGAVFLLYFITV---VWARRKDLQDQVKVKVTVLEDNDPLAEYRYLLVISTGHRRGASTSSQVTVTVTGSVWESEPHH-LTDPDKP-VFERGGVDMFLLSTPFNLGDLQSIRLWHDNSGTHPAWYVNKVMVQDLENGQKWHFLCSSWLAIDMGECTLDKVFSLATETDLKRFSNLFFMKTAKDLFDGHLWFSVISRPANSRFTRVQRVSCCFSLLLGTMLTGIMFWGIPSDPSEQS---VTIGSIKFSWRQLMVGIQSSIIMFPVNLLIVSIF 879 HSP 2 Score: 136.732 bits (343), Expect = 1.157e-31 Identity = 155/643 (24.11%), Postives = 286/643 (44.48%), Query Frame = 2 Query: 2288 LPKGFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPIILL---IIFVLAKKLLGAVSTDQEANIDEFVKDDLKKVLG--------------ANLNPPDQEKLEKIKKDKASGQRLSRVVGXXXXXXXXXXXXXXXXXXXRSQVTFDQTKMIRSRFIK--SNVQTYMDFYDWAQGILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISALVSKVYGNVP-CNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTYAETIDENLFDYDKEMVD 4156 LP F+FVGW L+ S +FT +Y L +G EKS WL + V F + L P+ +L + F L K + D E I + +K+ + G + PP + K+K+ Q+ ++ + L Y+ +L AY R F T+ I+ F S+ + D + WA L N G + I + G R+RQ+RV++++C + S V +VP C+ Y+ ED S+ WT L DSN ++ +P Q YQ + + G +Y GGG++ L Q+ ++ +++ L N WLD TRA+F E TVYN N NLF + ++ E G + + +++ RL+ G I L+ + +Y L ++ ++ + K + +QK EYF + WN++EL I LS S +++ + ++ + SF + + L + ++ I++ M N ++++ T+ +A++ +SS + + +A+ V N+LF + L+ + ++ + + I Y ++ + P A F + ++FI ++ + +++ + ++E+VD Sbjct: 1072 LPWWFVFVGWFLIAATSGVSAYFTMMYGLTYGKEKSISWLISLSVSFFQSLLLIQPVKVLGFAVFFALVVKSVDDDDEDDEEYI-KMLKNKVPAFSGDPDDVRISRRNSSCSFYQPPPPSDVGKMKEIWIKDQKAFALIWEILIYLGFFCMLLMAAYSQRDPNAFFLTRHIQQSFSNGISDSMSQQDVFIWANSSLLT----------NLFGQYSGFITDGNSKLVGTARLRQVRVQKSSCRKA---SSVRSSVPDCHAPYSWEVEDMGSYGPGWTSLI-------DSNMSKALFTPWQ-------YQTQSRLRAHTVWGGMALYRGGGFVVDLEPDQQNSSSVLQYLFENAWLDIYTRALFIEFTVYNANVNLFCIVTLMLETTAVGAFQ-YRTELQNIRLFQTTDG--IPTLVSEAIYFLFILYYMFLQAKLMKQQKWEYFRNKWNILELAIILLSWSAFSVFIKKMVQGDQDLKYYQDHRNQFPSFYETAAADSVLGYLTAVLVLLATIKMWHLMRLNSKLNMITNTLQQAWSDISSFIVVIVIMFLAYSIVSNLLFGWKLYTYKTLIDAATAMVSLQLGIFNYEEILDLNPVL-GAFIIGSCIIFMTFVVLNLFISVILEAFSQEQRHHKPSEEEEIVD 1682
BLAST of PKD1L-2 vs. Ensembl Cavefish
Match: pkd2 (polycystin 2, transient receptor potential cation channel [Source:NCBI gene;Acc:103043751]) HSP 1 Score: 120.939 bits (302), Expect = 4.402e-27 Identity = 126/510 (24.71%), Postives = 227/510 (44.51%), Query Frame = 2 Query: 2774 VQTYMDFYDWAQG-ILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISA-LVSKVYGNVPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTYAETIDENLFDYDKEMVDHVWNIFNEMMTGFKSSMKYTVPDALKKKAIVPVDMSDVDMQFASKEN 4297 + T DF+ + +G LN Y VWYNN ++ ++ + L G R+RQ++V +C + L +VY C Y+ SED F +K N++ W +Y I G + G Y GGGY L +E++A ++ L+ N WLD+ TRA+F + +VYNGN NLF +++L E P +GG + + ++ RL Y+ + ++++ L V+ + E+ ++ + YF S WN ++++ + LS II R N + L N Y +F L + F++ +++ K++ FNK +S + T+ R L MF +A+ + ++F F+ + F + + + ++ ET +Y+ + + ++F+ I+NDTY+E + ++ EM I + + G++ +M V L+K + D+SD Q K N Sbjct: 212 LSTMEDFWKYTEGPFLNGMYWDVWYNN--KSLPENQSLIYYENLLLGVPRLRQVKVLNKSCPVHEDLKDEVYD---CYSIYSPASEDKAPFGLK-----------NNTAW---------------VYSEENILGESSYWGEVATYRGGGYYQDLARSREESARQLKELKDNLWLDRGTRAVFLDFSVYNGNVNLFCIVRMLVEFPATGGA-VTSWQFQTVRLVRYVSSWDYFVGTCEVVFCLFVLYYMVEEVLEIRLHRLRYFKSLWNCLDVIIVTLSAPAIIMNIYRTSAVSNRLRYLLENHSTYPNFQPLAQVQVQFNHLAAVIVFLAWVKLFKFINFNKTMSQLSTTMSRCAKDLLGFAIMFFIVFLAYAQLAYLVFGNQLNDFSTFQACIFTQFRIILGDFDFSEIEETNRVL-GPIYFTTFVFFMFMILLNMFLAIINDTYSE-VKADMAQQRSEM-----EITDLIKKGYQKAM---VKLRLRKTTV--DDISDSLRQAGGKLN 677
BLAST of PKD1L-2 vs. Ensembl Cavefish
Match: pkd2l1 (polycystic kidney disease 2-like 1 protein [Source:NCBI gene;Acc:103031316]) HSP 1 Score: 114.39 bits (285), Expect = 3.798e-25 Identity = 118/480 (24.58%), Postives = 217/480 (45.21%), Query Frame = 2 Query: 2717 SQVTFDQTKMIRSRFIKS---------NVQTYMDFYDWAQG-ILNESYPKVWYNNMN-RTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISALVSKVYGNVPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTYAETIDE 4123 S T+ TK++ F+ + ++ T DF+ +AQG +L+ Y WYNN + +TG T + + + G R+RQ++VK +C + + + C + YN ED SF + N + W Y + + + T SGG ++ L + +E++A ++ NL N WLD TRA+F + + YN N NLF I+++ E P +GG + Y +R+ +L Y+ ++ +I++ + ++ I EI ++ K YF S WN+++++ I L++ I+ R + + L Y F+ W + ++ F + I++ KY+ FNK ++ + T+ R T + MF A+ +G +LF F+ + F + + Y D E +Y+ + F + ++F+ I+NDTY+E +E Sbjct: 142 SSTTYYYTKVMTDLFVNAPSDSGVTFQSIGTMDDFWSYAQGPLLDGLYWTSWYNNQSLQTG--THSFIYYENMLLGVPRVRQLKVKNKSCKVHKDFEEEISD--CFDVYNEKKEDDSSFGL-----------INGTAWQ--YHTEKELKGSNHWGMLATYSGGGYYQ-------------DLALTKEESAGVLANLNNNLWLDHGTRAVFIDFSTYNANINLFCVIRLVVEFPATGG-AIPSYQIRTVKLIRYITTWDYFIIGCEIVFCVFILYYIVEEILELRIHKLSYFKSIWNILDVVIIMLAIVAIVFNVFRTIKVDKLLGNLLKEPSIYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCATDILGFAIMFFIVFFAYAQLGYLLFGTEVESFSTFHKCIFTQFRIILGDFDY-DGIERANRVLGPIYFFTYVFFVFFVLLNMFLAIINDTYSEVKEE 589
BLAST of PKD1L-2 vs. Ensembl Cavefish
Match: pkd1a (polycystic kidney disease 1a [Source:ZFIN;Acc:ZDB-GENE-100707-1]) HSP 1 Score: 93.5893 bits (231), Expect = 1.910e-18 Identity = 50/134 (37.31%), Postives = 78/134 (58.21%), Query Frame = 2 Query: 1475 RRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLS--DSKFDG 1870 RR S++ PL D Y+Y I V TG R AGT++ + ++L G G SGHR + R G F ++ F + TD+ LG ++ +R WH++ G+ P+W L+ ++++D+QT Y F+ E WLS + K DG Sbjct: 3079 RRASVV----PLCGKDGLYKYE--IQVKTGWSRGAGTTAHVGVSLHGSEGRSGHRHLD---RVGAFTRNSLDIFHIATDTSLGSVLKIRAWHDNKGLSPAWLLQYVLVKDLQTGSSYFFLVEEWLSVDNEKTDG 3203
BLAST of PKD1L-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007306.1 (pep scaffold:Pmarinus_7.0:GL480012:400827:419749:1 gene:ENSPMAG00000006595.1 transcript:ENSPMAT00000007306.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 170.244 bits (430), Expect = 6.777e-43 Identity = 121/398 (30.40%), Postives = 199/398 (50.00%), Query Frame = 2 Query: 1316 FSAKIFIAPNMIDFKNVFANFASLLANSXXXXXXXXXXXXXXXXXXXXMWRKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGI--KPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVL--LEIKRDEKFQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTGIISVLITYPCIFIASEIFXXXXXXXXXXX--------EDQEAKMKKMFLLPK-----GFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPI 2458 F+A+ F+ PN IDF VFA F L +N+ V VI ++ + +LLL+ R DRR+ + PL+DND + Y Y++S+ TG AGT S ++ + G +G R + +G+ G F G+ F MT G+ + IWH++SG + SW L +++ DI + + F C+ WL+ DG R L + +F S + D H+ + S ++RVQ+++ V++ FL MV+NAM+F + D + G +++ + G++S LI +P F+ +FRR E +K L + + FV WSL+F+++V S FFT LYS++WG +K+N WL+ F + F + + P+ Sbjct: 1 FAAEFFVPPNTIDFATVFAKF-DLRSNAAVFTTVIAILLLYFLLLLYAR-RADRRDKDNWKIRPLVDNDDSHAYVYLLSIVTGMRAGAGTQSRVYFTVHFSLGDTGTRILHNGHLKG-FSRGSTVTFEMTVPYYWGEPKNITIWHDNSGPGGQGSWFLRHILLHDIHAKQTFAFPCDRWLAAEFEDGQLCRELPVAGFQFVPSTGMVFSSTVQSKITDDHMWVSVFMRPTRSAFSRVQRISCCVSLLFLTMVTNAMWFETGPSTGSD---NVQIGPFTLSLSEMLIGLMSNLIVFPISFVIVAVFRRQTYSPATLRFFETHGKGEGDPGPWRKPPLCRRITATAFYKFVAWSLVFLSVVTSGFFTILYSMEWGPDKANLWLRVFIMSFFQSIIIVQPV 392 HSP 2 Score: 95.1301 bits (235), Expect = 7.496e-20 Identity = 96/451 (21.29%), Postives = 183/451 (40.58%), Query Frame = 2 Query: 2810 GILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIR-VKRN------------TCTISALVSKVYGNVPCNENYNLLSEDTRSFSV------KWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTY 4105 G L YP+ WYN + + +R GP R+RQIR V R T + + V N C E R + + + P+ + S++ LY GG+ IA LG+ I+ NL + +WLD TRA+ E T YN NT+LF ++ +L E G + +R+ ++ + ++ I++A+ +V+ E ++ + YF S WN+ ELLSI L + ++ +++ V + + +V+F + +W + L+ FVS I+VL +M + ++ G A + + + +F + ++LF+ + + T LF + + YG+++ +Y+ +++++ F I + + IL++ + Sbjct: 657 GFLPNFYPRAWYNGERMSWRERYYLRDFSTIRVGPGRLRQIRSVPRAWNLLLSAPTAVATLSRAPYVVAARANQRCGEGTTQRKRAVRQYQIFSHRVTQLVPVWHPSLA---------------------LYSG----GGF--------------IAELGLNLADGTEIVANLSSASWLDHSTRAVLTEFTGYNMNTDLFCSVTLLLEFSQGAGDAHGHAYIHVFRIESFVGKLETLTGVVYIVFAILLVIIAATEALRLSELGVAYFKSFWNIAELLSITLGAASVVTYFIKMSVATRTLEKFRTDPHKFVNFQELVTWDQQLSELLATLVFVSTIKVLGHMKSLRQFEVLVGAFSEARDHIQGFAVIVVVVFCSFGQLTSLLFAGSLRNYRTFTTCLEQLFSLLLGQPGYGELYAANRVLGPLIYF-AFTSVNTFVIVNFSLGILSEGF 1067
BLAST of PKD1L-2 vs. Ensembl Sea Lamprey
Match: pkd2l1 (polycystic kidney disease 2-like 1 [Source:ZFIN;Acc:ZDB-GENE-030616-558]) HSP 1 Score: 115.931 bits (289), Expect = 1.483e-26 Identity = 131/585 (22.39%), Postives = 257/585 (43.93%), Query Frame = 2 Query: 2726 TFDQTKMIRSRFIKS-----------NVQTYMDFYDWAQG-ILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISALVSKVYGNVP-CNENYNLLSEDTRSFS----VKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTY-------AETIDE-NLFDYDKEMVDHVWNIFN-------EMMTGFKSSMKYTVPDALKKKAIVPVDMSDVDMQFA-SK--ENIRNMVSKRVNPSLRRKLADLNGEKYK 4375 T+ TK++ F++S ++ + DF+ QG +L+ Y + WYN +L+ I + + P R+RQ++V+ +CTI L + +P C + Y+ ED +F W + +S S+W L + +G Y L ++ ++A +++ L+ WLD TRA+F + T YNGN NLF ++++ E P +GG + Y R+ +L Y+ ++ ++++ ++ + E ++ +YF S WN ++++ I LS+ II R + N + L + Y F+ W ++ I+ F + I++ KY+ FNK ++ + T+ R + MF A+ G ++F F++ + + F + + + + E +Y+ + F + ++F+ I+NDTY A+T D+ + D+ K+ ++ N +M S+ K+ D + +K ++ + SD ++ A SK ++ N++ + LR A+L G+K K Sbjct: 56 TYYYTKVMMDLFVESPVSPIDGTNFNSISSMDDFWKVVQGPVLDGLYWEKWYNGDQLPVNLSF-IQYENVMLGVP-RVRQLKVRNGSCTIYPLFRNI---IPGCYDGYSCGEEDKETFGRGTGTAWKYWSEEELS-GSSHWG--------------LLAQYSGAGYY---------------RDLSRRKNESAPMLQELKDYLWLDHGTRAVFIDFTTYNGNINLFCVVRLVVEFPLTGG-ALPSYQFRTVKLIRYVSAFDYFIMACEVIFCCFILYYVVEECLELRLHGMKYFKSVWNCLDIIVIVLSMVAIIFNICRTIAVSNLLGALLNDPNIYADFEYLAFWQTQFNNMLAINVFFAWIKIFKYVSFNKTLTQLSSTLARCAKDVLGFAVMFFIIFFAYAQTGYLVFGSQVEDFSSFVNCIFTQFRIILGDFDFHAI-ENANRILGPIYFTTYIFFVFFVLLNMFLAIINDTYTDVKAELADTKDDFEIGDFFKQGYKNMLNKLKMKKDDIADMQRALDSAGKHLEYD-IWRKNLIRLGHSDEEIAAAFSKFDKDSDNVLDEDEQKQLR---AELEGQKDK 599
BLAST of PKD1L-2 vs. Ensembl Sea Lamprey
Match: pkd2l1 (polycystic kidney disease 2-like 1 [Source:ZFIN;Acc:ZDB-GENE-030616-558]) HSP 1 Score: 115.931 bits (289), Expect = 2.049e-26 Identity = 120/455 (26.37%), Postives = 205/455 (45.05%), Query Frame = 2 Query: 2780 TYMDFYDWAQG-ILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISALVSK-VYGNVPCNENYNLLSEDTRSFS-VKWTPLANSSVSFNDSNWNRNY-LSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFI---TSVFICILNDTYAETIDE 4123 T+ DF+ QG +LN Y + WYN++ + + + G RIRQ++V+ ++CT+ A K V G C Y+ +ED SF TP S+ S D N + ++ L T + GGY + L + ++A ++++L WLD+ TRAI + + YNGN NLF+ I++L E P +GG + + + +L Y+ G+ +L + ++ ++ I EI ++ K YF S WN ++LL I LS+ II R + + L Y +F W ++ ++ F I+ KY+ FNK ++ + T+ R + MF A+ +G +LF F+ + F + + + + E LY+ + VFF+ ++F+ I+NDTYAE +E Sbjct: 171 TFDDFWKVVQGPVLNGLYWEKWYNDIPLVEN--QSFIYYENFLLGVPRIRQLKVRNDSCTVHADFQKDVQG---CYAAYSEDAEDKASFGPATGTPWKYSTSS--DMNGSSHWGLLATYS------------GGGYYLD--------------LTRSKSESAILLQDLFDKQWLDRGTRAILIDFSSYNGNINLFSVIRLLVEFPPTGG-AVPSSQIYTVKLIRYVTGSDYFILACEGIFCCFILYYIVEEILELSIHKFAYFKSVWNCLDLLVIMLSVVAIIFNVYRTVTVNKLLKALLDEPNRYGNFQFLAFWQTQYNNMVAVNVFFCWIKFFKYVSFNKTMTQLSSTLARCAKDVLGFAVMFFIIFFAYAQLGYLLFGTQVEDFSTFSNCIFTQFRIILGDFDF-NAIENANRVLGPLYFTTY-VFVVFFVLLPKNMFLAIINDTYAEVKNE 589
BLAST of PKD1L-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010652.1 (pep scaffold:Pmarinus_7.0:GL477016:137094:159626:-1 gene:ENSPMAG00000009641.1 transcript:ENSPMAT00000010652.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 97.8265 bits (242), Expect = 1.545e-20 Identity = 56/202 (27.72%), Postives = 98/202 (48.51%), Query Frame = 2 Query: 1466 RKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVLLEIKRDEKFQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAM 2071 R DR + PL DN P Y +++ TG AGT++ + L G+ G+S R++ LFE + F+M+ LG + L +WHN+ G PSW + ++ + D+ + ++F E WL+ + DG ER LL + +F L + + D H+ A + + S +T Q+++V + + +NA+ Sbjct: 1307 RWDRHDEHKAGAIPLQDNLPSDRQLYEVTLETGFRAGAGTTAKANVILHGEHGTSETREL-HCEDKPLFERNSTHTFIMSVPDSLGPIWKLHLWHNNRGASPSWFVSRVTVRDLWSGSAWLFPAECWLAAERGDGRVERELLALSGALRFTALLYSKVTAYLEDFHLWASVYSRPSCSRFTHTQRLSVCLCLLLAYAGANAL 1507
BLAST of PKD1L-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010650.1 (pep scaffold:Pmarinus_7.0:GL477016:137070:158392:-1 gene:ENSPMAG00000009641.1 transcript:ENSPMAT00000010650.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 97.4413 bits (241), Expect = 1.739e-20 Identity = 56/202 (27.72%), Postives = 99/202 (49.01%), Query Frame = 2 Query: 1466 RKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVLLEIKRDEKFQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAM 2071 R DR + PL DN P Y +++ TG AGT++ + L G+ G+S R++ + LFE + F+M+ LG + L +WHN+ G PSW + ++ + D+ + ++F E WL+ + DG ER LL + +F L + + D H+ A + + S +T Q+++V + + +NA+ Sbjct: 1299 RWDRHDEHKAGAIPLQDNLPSDRQLYEVTLETGFRAGAGTTAKANVILHGEHGTSETRELHCEDKP-LFERNSTHTFIMSVPDSLGPIWKLHLWHNNRGASPSWFVSRVTVRDLWSGSAWLFPAECWLAAERGDGRVERELLALSGALRFTALLYSKVTAYLEDFHLWASVYSRPSCSRFTHTQRLSVCLCLLLAYAGANAL 1499
BLAST of PKD1L-2 vs. Ensembl Nematostella
Match: EDO44884 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUD7]) HSP 1 Score: 254.603 bits (649), Expect = 2.484e-69 Identity = 248/1040 (23.85%), Postives = 466/1040 (44.81%), Query Frame = 2 Query: 1217 WNFNMEVWQDFSASVDDTSDISNINFKSNFLGTFSAKIFIAPNMIDFKNVFANFASLLANSXXXXXXXXXXXXXXXXXXXXMW--RKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGL-FETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVLLEIKRDE--KFQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTGIISVLITYPCIFIASEIFX-----------------------XXXXXXXXXXEDQEAKM--------------------KKMFLLPKGFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPIILLIIFVLAKKLLGAVSTDQEANIDEFV---------KDDLKKVLGAN-----LNPPDQEKLEKIKKDKASGQRLSRVVGXXXXXXXXXXXXXXXXXXXRSQVTFDQTKMIRSRFIKSNVQTYMD--FYDWAQGILNESYPKVWYN--------NMNRTGDLTTAIAICDC---LRQGPFRIRQIRVKRNTCTISALVSKVYGNVPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTYAE 4111 W+ E W V + S + N L F +KIF+ PN +D + AN + +V ++ I L + V+W R+D+ +++ + N P Y Y I V G+ R AGT++++ I L G S + D R+ G+ +F++TT LG L +R+WH+++G P+ ++K+++ D T + F+C W + + DG +RV+ ++E F+ +F + D H+ I S +TRV++V+ ++ M++NAM++ + +N ++D G + +W Q GI+S ++ +P + +IFR T K ED + + KK+ LP ++GW L+ + ++AS T +Y +Q+G S +WL + F+ + +F+S P+ ++++ + +L +DQ N +E K D V+ L + LEK + +++S ++ D TY+ L +L +A+ + Q++ I +K+ ++ + Q I N+S +W N N++ TA + L G R RQ+R K++TC I+ ++ V + C + Y++ ++D +++ +W P S V P+ + I +F + + GYP+ G Y GGGYI +A I++ + N+W+D+ T +F E T+YN +NLFT VL E +GG + P ++RLY + I L+ +++ L +RE+KK+ K K YF WN E++ + L+ + + + + + + N Y +F ++W + ++GI F+S I+ +K + FNK + ++ T+ R+ L+ G MF+ ++F +L + F+ + S L V + + + F P A + ++ L+ F + ++FI I+ +++ E Sbjct: 19 WDEVQENWSTRGCRVGPNTSSSRTHCLCNHLTWFGSKIFVPPNTLDLSLIRANIQD---PAQYAAVVSVMCIIWGLYAIGVVWARRQDKNDALKVGVHFSPSNRPGSRYLYEIVVCVGTRRRAGTTANVAIKLYGDQQDSQPFLLDDSNRNSTPLSRGSNNSFIVTTSEALGQLSYIRVWHDNTGSNPALFVKKVIVRDHVTGDTWHFLCNRWFAVDEGDGMIDRVVPMTSQEELKHFKTIFMDKTKKDLTDSHLWFSIVWRPPDSNFTRVERVSCCLSFLLCTMMANAMWY----EVPTGSNTQVDIGPVQFSWEQVSIGIMSSMVVFPINLVIVQIFRNCKAKKNRGKRLLGSPKGGNRVCVTSNSKILHHEDIDTHISLPSDTSRTSFWSNKRSKNPKKIKSLPWWMTYIGWLLVTLTVLASTVVTLMYGIQFGKHTSEKWLLSMFISVTHDIFISQPLKVILLALFFAYVLKKPPSDQNNNANELDSKELLQQCNKRDTNDVIDVEAPSVPLGALSNDALEKARDRNDKERKMSVILTDIGTYLTFLWVLLVIAHSRVDSAAYWQSRSISDVLMKTTYESPPESGLTKTFQKISNDSEIWLWTNHVLLPALYNLDWYYYTKTAPKLVRGGAGLVVGFARWRQLRKKKDTCLITGVMRGVIHH--CTDPYSMSTQDETNYNSRWRPFNTSDVP------------PSPSTIWSF--NSASKLNGYPYFGEISTYSGGGYIVPFSSIYYKAVKEIKHARNNSWIDRYTAGLFTEFTLYNPYSNLFTASTVLVEVLPTGGFHVRP-EFFTFRLYSLVGDFHIFTLVCDVVFLLFTSYFTFRELKKLYKDKCSYFRDYWNWAEIVIMVLAWIAVADYFICLGIRKWTLKLHQENPNDYTNFQYISAWQMSFESILGILVFISTIKFIKLLRFNKKMFLLAYTLSRSAKDLAHYGIMFLIVFLSFAQFYYLLLGSDYDSFSTFVKSIEKLINVLLGRFSFEE-FLIPFRIMGAFGFFLYMTLTNFLLLNMFIAIIVESFTE 1033
BLAST of PKD1L-2 vs. Ensembl Nematostella
Match: EDO43195 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZ92]) HSP 1 Score: 220.705 bits (561), Expect = 2.574e-59 Identity = 224/817 (27.42%), Postives = 362/817 (44.31%), Query Frame = 2 Query: 1211 RIWNFNMEVWQDFSASVDDTSDISNINFKSNFLGTFSAKIFIAPNMIDFKNVFANFASLLANSXXXXXXXXXXXXXXXXXXXXMW--RKDRRES-----ILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVLL-EIKRDEK-FQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSG-DANFKIDFGLISITWFQFYTGIISVLITYPCIFIASEIFX----------------------XXXXXXXXXXEDQEAKMKKMFL--LPKGFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPIILLIIFVLAKKLLGAVSTDQEANIDEFVKDDLKK-----------------VLG--ANLNPPDQEKLEKIKKDKASGQRLSRVVGXXXXXXXXXXXXXXXXXXXRSQVTFDQTKMIRSRFIK--SNVQTYMDFYDWAQGI-LNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCT--ISALVSKVYGNVPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYL-PGNMIVLLLMQIL 3484 + W+ EVW+ V + + ++ I+ N L F + +APN IDF V+A F ++ N + +V+ + L +V+V+W RKD+ + I+L + + + P E+ Y +S+HTGS R + T++ + LG L+ +RIWH+ SG SW L ++ +I+TN +IFMC+ WL+ K DG +RVLL +D K F+ LF + + D H+ + S +TRVQ++T +++ + M++ AMF+ N+ G N I G ++ + Q GI S I P I +IFR + K+ +E+ + KK+ L LP +++ W+L ++ S T YS+ WG + SNQWL + V F F++ PI + I V +L + D EF + D K +G + + PD +EK +K K ++ ++ +++ L LL + Y++R ++++Q K+I K S V F+ + I L ++ + YN + R + TA + G R RQ+RVKR C I+AL C + Y+ +ED F W AN S + W TV P+ G G YGGGGY A LG QA I+++L NNWLD+ TRA F E TV+N NLF+ L E +GG + ++RL+ ++ G +V+LL ++ Sbjct: 44 KYWDIKKEVWRTDGCKVGNLTTLNKIHCICNHLTAFGGGLLVAPNPIDFDKVWAGFKNISDN---LAVVVTIATGFGLYIVLVLWARRKDKGDMEKVKLIVLGFSTVETDTPFGEHLYELSIHTGSWRGSSTTAKV----------------------------------------LGPLLYIRIWHDMSGYDSSWYLNFVIAREIETNANWIFMCDRWLALEKDDGMVDRVLLVSTDKDLKTFKTLFNTKVSTDLFDGHLWMSVVKKPPKSSFTRVQRLTCCMSLLYTTMMTGAMFY----NVGGVKDNSTISLGPLTFSVRQLMIGIQSSFIALPGNMIVIQIFRNLKPQEVQSEVNNSAISKEDNLKNASEKQSNSEEDKPNGKKVCLNELPHWLLYIAWTLCISMILVSATITLFYSMMWGKDISNQWLSSMLVSFFQDAFVTQPIKVCAIAVFVAAVLKTLPKD----FSEFKQRDKKHKSPIGSCSSMKSQEQKDTIGKKSAMELPDPVTIEKARKFKLKETQMIGIMSSISLHIVFLTLLVVVGYNSRDPMSYNQMKVIEDGISKTVSLVVNIKGFWGYVGNIVLPFAFNERGYNGLPRHKEGVTADT--NLFMIGMPRFRQLRVKREKCEREITALW--------CYDAYSAFNEDKSYFLPGWRTRANLSFTECPVPWRHKDFIELNTV---------------PYWGNLGWYGGGGYTADLGYNIIQAQGIVKDLVRNNWLDQQTRATFIEFTVFNAQVNLFSVTTFLLESLGTGGGFSL-LKIDTFRLHPHVGSGQTLVILLESVV 783
BLAST of PKD1L-2 vs. Ensembl Nematostella
Match: EDO32324 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SVF4]) HSP 1 Score: 172.555 bits (436), Expect = 1.607e-43 Identity = 130/448 (29.02%), Postives = 216/448 (48.21%), Query Frame = 2 Query: 1211 RIWNFNMEVWQDFSASVDDTSDISNINFKSNFLGTFSAKIFIAPNMIDFKNVFANFASLLANSXXXXXXXXXXXXXXXXXXXXMW--RKDRRE-----SILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVLL--EIKRDEKFQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFK-IDFGLISITWFQFYTGIISVLITYPCIFIASEIF--------------XXXXXXXXXXXED---QEAKMKK-----MFLLPKGFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPI 2458 + W+ E+W + + ++ L F + +APN IDF V+A F ++ N + +V+ + L + +V +W R D ++ + L D YE ++++TGS + + T++++F+N++G G +G +TD + LF G FV+ D LG L LR+WH+ +G SW L +I+++Q + +IFMC WL+ K DG +RVLL + + F+ LF + + D H+ + S +TRVQ++T +++ F M+++AMFF N+ GD + + G ++ + Q GI S I P + +IF ++ KRR TED ++A KK LP F++V W+L ++ S T YS+ WG E SNQWL + V F FL+ PI Sbjct: 168 KYWDKEREMWSTMGCKAGPQTRLEVVHCVCTHLTAFGGGLLVAPNPIDFDKVWAGFKNISDN---LSVVVTIAVALAIYIVCAVWARRMDNKDINKDGVTTITSTNTLHGDHIYE----LTLNTGSWKGSCTTANVFVNIIGDKGQTGPLSLTDSSKQ-LFTEGAANTFVIPLDLSLGQLRYLRVWHDMTGYDSSWFLNFAIIKNLQMDSKWIFMCSRWLALEKDDGLVDRVLLVSTVAELKNFKTLFNTKVSNDLFDGHLWMSVVKKPPRSPFTRVQRLTCCMSLLFTTMMTSAMFF----NIGGDPDTSTVSLGPLTFSVRQLIIGIQSSFIALPVNILVVQIFRNLPLLKAPEDGTHKKKASEKRRKTEDSTHEKAVPKKNNKICPEQLPYWFLYVAWALCVTMILTSAAITLFYSMMWGKEISNQWLASTLVSFFQDAFLTQPI 603 HSP 2 Score: 147.132 bits (370), Expect = 1.401e-35 Identity = 96/298 (32.21%), Postives = 163/298 (54.70%), Query Frame = 2 Query: 3221 ASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYL-PGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTYAE 4111 A LG QA II +L+ N WLD LTRA F E TV+N NLF+++ LFE +GG ++ V ++RLY ++ PG +V+L + +T++L Y+ IKK+ + K EYF WN+V+L+ I L+LS ++ +R++ T I L N +VSF AT W E + ++GI F+S +R+L + FN++IS++ +I R+++ L+ I +F ++F + F + SLF + + Y D+ + L + V++ + F+ ++F+ I+ + Y E Sbjct: 695 ADLGYNTGQADSIIVDLKKNRWLDHLTRATFIEFTVFNAQVNLFSSVTFLFESQGTGG-GIYLLKVETFRLYPHVGPGQTLVILCEITVVVVTLILA-YKNIKKIYRMKMEYFKQTWNIVQLVVICLTLSAVVLFILRMLDTQKTIKKLRENPFVFVSFQYATQWAELNTYIVGIVIFLSTLRLLYLISFNRHISMLYNSISRSFSLLAQFAVEVIIVFTSFAIFTYVVFGSHMDGFGTFQGTLGSLFAMLLGKGYYSDLSQVDVIL-GPLLFAVFTTTMMLFMLNIFVAIVMEPYEE 989
BLAST of PKD1L-2 vs. Ensembl Nematostella
Match: EDO46983 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNS6]) HSP 1 Score: 151.369 bits (381), Expect = 7.248e-40 Identity = 97/303 (32.01%), Postives = 164/303 (54.13%), Query Frame = 2 Query: 1298 SNFLGTFSAKIFIAPNMIDFKNVFANFASLLANSXXXXXXXXXXXXXXXXXXXXMWRK-DRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTD--GYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVLLEIKRDE--KFQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTGIISVLITYP 2191 N L +F A + +APN IDF VFANFA++ A ++ + L ++ I++ R+ D+R+ ++ P+ + + YSY +SV+TG+ R +GT++ + + G S +TD G + + G V F++ T LG + + IWHN++G PSW L ++VIED+QT K F+ WL+ K +G E+++ + E KF+NLF DKH+ + + +S +TRVQ+VT +++ M++NAMF+ D G ++ +I G I+++ Q G S L+ P Sbjct: 22 CNHLTSFGAGVMVAPNPIDFDQVFANFANITATGNFSVLFTVCGLFLLYIIAIILARRADKRDKKMVCVSPVPTS--KSGYSYQVSVYTGTFRGSGTTAKASLIISGDHHDSPIIPLTDASGNSEEVLSRGNVAQFIVNTPVCLGPINYIHIWHNNAGDDPSWFLRQVVIEDVQTMKKMFFLLSDWLALDKGEGIVEKIIYTATQKEMGKFKNLFYTHTSKSFSDKHLWISVVLRSPLSPFTRVQRVTCCLSLCLCAMLANAMFYQID----GGSDNEITIGPITLSLRQIMVGAQSSLVIIP 318
BLAST of PKD1L-2 vs. Ensembl Nematostella
Match: EDO40050 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S8E4]) HSP 1 Score: 148.673 bits (374), Expect = 2.640e-39 Identity = 99/308 (32.14%), Postives = 164/308 (53.25%), Query Frame = 2 Query: 1175 LLLSLGVASLTPRIWNFNMEVWQDFSASVDDTSDISNINFKSNFLGTFSAKIFIAPNMIDFKNVFANFASLLANSXXXXXXXXXXXXXXXXXXXXMWRKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDS-----PLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVLLEIKRDE--KFQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFF 2077 L ++L + + + R W+ ME W + VD + N L +F++ +F+ PN ID+ A L+ YV ++ + LYL+ +I + D+ ++ P+ DNDP Y Y I +HTG R AGTS+D+ I L G S R + D R +F+TG V F++T PLG+L +R+WHN+ G PSWNL +++I+D+QT++ + F+C+ WL+ + DG +RV+ ++E KF LF + D H+ + S +TRVQ++T +++ M++N MF+ Sbjct: 1 LNVTLTIFTSSCRYWDNKMEQWSS-AGCVDIRTRTDYTLCLCNHLTSFASGMFVPPNTIDWDKFLA---FDLSQGYVCFATVLTVIGLYLVFLIPARKADKADAEKTGVTPIPDNDPRDTYCYEIHIHTGFIRGAGTSADVSIVLNGAVADSDPRVLKDPKRK-VFKTGGVDAFLLTVPHVYRVFPLGNLKNIRLWHNNGGAYPSWNLLRVMIQDLQTDQRWWFVCDDWLAVDEGDGKIDRVIYPATKNELTKFNVLFATEVRKNLTDGHLWFSVVTRPANSPFTRVQRLTCCLSILLCTMLANLMFY 303
BLAST of PKD1L-2 vs. Ensembl Medaka
Match: pkd1l2a (polycystin 1 like 2 [Source:NCBI gene;Acc:101162200]) HSP 1 Score: 239.58 bits (610), Expect = 1.940e-63 Identity = 252/1048 (24.05%), Postives = 456/1048 (43.51%), Query Frame = 2 Query: 1211 RIWNFNMEVWQDFSASVDDTSDISNINFKSNFLGTFSAKIFIAPNMIDFKNVFANFASLLANSXXXXXXXXXXXXXXXXXXXXMWRKDRRESILLRYE--PLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVL-LEIKRDEKFQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDA-NFKIDFGLISITWFQFYTGIISVLITYPCIFIASEIFXXXXXXXXXXXEDQEAKM--KKMFLL-----------------------------------PKG------------------FIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPIILLIIFVLAKKLLGAVSTDQEANIDEFVKDDLKKVLGANLNPPDQEKLEKIKKDKASGQRLSRVVGXXXXXXXXXXXXXXXXXXXRSQVTFDQTKMIRSRFIK--SNVQTYMDFYDWAQ-GILNE---SYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISALVSKVYGNVP-CNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTYAETIDENLFDYDKEMVD 4156 + WN + W + V + N L F + F+ PN++D FA+ AN+ VV+ + IF Y+L+V+ RKD ++S L+ + L DNDP EY Y++++ TG R A TSS + I L G G S +TD + +FE G + F++TT LG+L ++R+WH++SG P++ + ++++D++ + F+C +WL+ + ++V + + D K NLF D HI + + S +TRVQ+V+ ++ M+++ MF+G + S + I+F TW Q GI S +I +P + IFR +R ++ D++ K++ LL P+G F+FVGW L+ S +FT +Y L +G ++S WL + V F +F++ P LK + PP +EK++ Q++ ++ + Y+ + +L +AY R + T+ IR F K S+ + D + WA +LN YP + N G+ R+RQ+R+++ +C + AL ++ +VP C+ Y+ EDT S+S W+PL+ ++ + N N ++Y++ YP G L A +++ L N WLD T+A+F E TVYN N NLF + ++ E + F ++S RLY G I ++ +++Y L ++ ++ + K + +Q+ YF S WNL+EL IFLS S + R ++ ++ NK +VSF + L+ ++ +++ + N + ++ T+ RA+T +S + +A+ N+++ + LL + ++ + + I Y ++ P + L + F I ++FI ++ + + + ++E+VD Sbjct: 393 KYWNESTSSWSEDGCRVGPLTTPLVTQCLCNHLTFFGSSFFVMPNLVDVSRTAELFATF-ANNPVVVCFVATIFAAYVLVVLWARRKDIQDSAKLQVKITDLGDNDPLAEYRYMLTISTGHRRGASTSSQVTITLQGTEGESEPHHLTDPEKP-VFERGGMDMFLLTTHFSLGELQSIRLWHDNSGDHPAY-VNNVMVQDLELGHKWHFLCNSWLAVDVAECTLDKVFPVATETDMKRFNLFFMKTAKDFRDGHIWFSVISRPPCSTFTRVQRVSCCFSLLLCTMLTSIMFWGIPTDPSEQTMDLHIEF-----TWQQVIIGIQSSIIMFPINLLIVSIFRNSRPREKVTKTDRQLHHVEKELGLLGPSRFPNPNNYNRAMQQVQGLKSHLESSLDGDKPSPEGSINGSTKKKQIQRGLPWWFVFVGWILVIATSGVSGYFTMMYGLTYGKDRSISWLISMVVSFFESLFITQP--------------------------------LKDSTCSFYQPPPPTDIEKMRNSMIKEQKVFSLI-KEILYMGFMWVLLLVAYGQRDPNAYFLTRHIRQSFSKGISDTMSIQDVFTWANTTLLNNLFGEYPFITDGNSKLVGNA---------------RLRQVRMQKGSCLV-ALPMQI--SVPDCHALYSWELEDTGSYSPGWSPLSGNNATLNPH--------------NPWIYKSQHKLRAYPICGN----------VKLYRGGGFATDVLQYLYDNIWLDVYTQALFVEFTVYNANVNLFCIVTLILE--TTATAFQFRSELQSVRLYQSTGGLHIFVMASEVVYFLFIIYYMFVQGKLMKRQRLAYFQSKWNLLELAIIFLSWSALSVFIKRTLLGQRDVSQYENNKDRFVSFHETAQADAVLGYLIAFLVLLATVKLWHLLRLNPKLHMITATLQRAWTDISGFLVVIAIMFLAYSVASNLMYGWKLYSYRTLLEAAQTIVSLQLGIFNYEEVLNYNPLLGAFLIGSC-IVFMTFVILNLFISVILVAFTQEQIHHKPSEEEEIVD 1354
BLAST of PKD1L-2 vs. Ensembl Medaka
Match: pkd1l2a (polycystin 1 like 2 [Source:NCBI gene;Acc:101162200]) HSP 1 Score: 152.14 bits (383), Expect = 2.215e-36 Identity = 157/636 (24.69%), Postives = 293/636 (46.07%), Query Frame = 2 Query: 2288 LPKGFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPIILLIIFVLAKKLLGAVSTDQ--EANIDEFVKDDLKKVLGAN--------LNPPDQEKLEKIKKDKASGQRLSRVVGXXXXXXXXXXXXXXXXXXXRSQVTFDQTKMIRSRFIK--SNVQTYMDFYDWAQGILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISALVSKVYGNVP-CNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTYAETIDENLFDYDKEMVD 4156 LP F+FVGW L+ S +FT +Y L +G ++S WL + V F +F++ P+ +L +L V D+ E I+E K +V+ A+ PP +EK++ Q++ ++ + Y+ + +L +AY R + T+ IR F K S+ + D + WA L NN+ G+ I + G R+RQ+R+++ +C + AL ++ +VP C+ Y+ EDT S+S W+PL+ ++ + N N ++Y++ YP G +Y GGG+ L + + + +++ L N WLD T+A+F E TVYN N NLF + ++ E + F ++S RLY G I ++ +++Y L ++ ++ + K + +Q+ YF S WNL+EL IFLS S + R ++ ++ NK F VSF + L+ ++ +++ + N + ++ T+ RA+T +S + +A+ N+++ + LL + ++ + + I Y ++ P + L + F I ++FI ++ + + + ++E+VD Sbjct: 1022 LPWWFVFVGWILVIATSGVSGYFTMMYGLTYGKDRSISWLISMVVSFFESLFITQPLKVLGFAAFFALVLKQVDLDEFGEPQIEENFKRTDPEVVPADRRDSTCSFYQPPPPTDIEKMRNSMIKEQKVFSLI-KEILYMGFMWVLLLVAYGQRDPNAYFLTRHIRQSFSKGISDTMSIQDVFTWANTTL--------LNNL--FGEYPGFITDGNSKLVGNARLRQVRMQKGSCLV-ALPMQI--SVPDCHALYSWELEDTGSYSPGWSPLSGNNATLNPH--------------NPWIYKSQHKLRAYPICGNVKLYRGGGFATDL-LPDLKNSSVLQYLYDNIWLDVYTQALFVEFTVYNANVNLFCIVTLILE--TTATAFQFRSELQSVRLYQSTGGLHIFVMASEVVYFLFIIYYMFVQGKLMKRQRLAYFQSKWNLLELAIIFLSWSALSVFIKRTLLGQRDVSQYENNKDF-VSFHETAQADAVLGYLIAFLVLLATVKLWHLLRLNPKLHMITATLQRAWTDISGFLVVIAIMFLAYSVASNLMYGWKLYSYRTLLEAAQTIVSLQLGIFNYEEVLNYNPLLGAFLIGSC-IVFMTFVILNLFISVILVAFTQEQIHHKPSEEEEIVD 1624 HSP 2 Score: 137.117 bits (344), Expect = 8.161e-32 Identity = 100/338 (29.59%), Postives = 171/338 (50.59%), Query Frame = 2 Query: 1211 RIWNFNMEVWQDFSASVDDTSDISNINFKSNFLGTFSAKIFIAPNMIDFKNVFANFASLLANSXXXXXXXXXXXXXXXXXXXXMWRKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVL-LEIKRDEKFQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDA-NFKIDFGLISITWFQFYTGIISVLITYPCIFIASEIF 2218 + WN + W + V + N L F + F+ PN++D FA+ AN+ VV+ + IF Y+L+V+ RKD ++S ++ L DNDP EY Y++++ TG R A TSS + I L G G S +TD + +FE G + F++TT LG+L ++R+WH++SG P++ + ++++D++ + F+C +WL+ + ++V + + D K NLF D HI + + S +TRVQ+V+ ++ M+++ MF+G + S + I+F TW Q GI S +I +P + IF Sbjct: 576 KYWNESTSSWSEDGCRVGPLTTPLVTQCLCNHLTFFGSSFFVMPNLVDVSRTAELFATF-ANNPVVVCFVATIFAAYVLVVLWARRKDIQDSAKVKITDLGDNDPLAEYRYMLTISTGHRRGASTSSQVTITLQGTEGESEPHHLTDPEKP-VFERGGMDMFLLTTHFSLGELQSIRLWHDNSGDHPAY-VNNVMVQDLELGHKWHFLCNSWLAVDVAECTLDKVFPVATETDMKRFNLFFMKTAKDFRDGHIWFSVISRPPCSTFTRVQRVSCCFSLLLCTMLTSIMFWGIPTDPSEQTMDLHIEF-----TWQQVIIGIQSSIIMFPINLLIVSIF 905
BLAST of PKD1L-2 vs. Ensembl Medaka
Match: pkd1l2a (polycystin 1 like 2 [Source:NCBI gene;Acc:101162200]) HSP 1 Score: 134.42 bits (337), Expect = 4.226e-31 Identity = 88/292 (30.14%), Postives = 154/292 (52.74%), Query Frame = 2 Query: 1211 RIWNFNMEVWQDFSASVDDTSDISNINFKSNFLGTFSAKIFIAPNMIDFKNVFANFASLLANSXXXXXXXXXXXXXXXXXXXXMWRKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVL-LEIKRD-EKFQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFG 2080 + WN + W + V + N L F + F+ PN++D FA+ AN+ VV+ + IF Y+L+V+ RKD ++S ++ L DNDP EY Y++++ TG R A TSS + I L G G S +TD + +FE G + F++TT LG+L ++R+WH++SG P+W + ++++D++ + F+C +WL+ + ++V + + D ++F NLF D HI + + S +TRVQ+V+ ++ M+++ MF+G Sbjct: 275 KYWNESTSSWSEDGCRVGPLTTPLVTQCLCNHLTFFGSSFFVMPNLVDVSRTAELFATF-ANNPVVVCFVATIFAAYVLVVLWARRKDIQDSAKVKITDLGDNDPLAEYRYMLTISTGHRRGASTSSQVTITLQGTEGESEPHHLTDPEKP-VFERGGMDMFLLTTHFSLGELQSIRLWHDNSGDHPAWYVNNVMVQDLELGHKWHFLCNSWLAVDVAECTLDKVFPVATETDMKRFSNLFFMKTAKDFRDGHIWFSVISRPPCSTFTRVQRVSCCFSLLLCTMLTSIMFWG 564
BLAST of PKD1L-2 vs. Ensembl Medaka
Match: pkd2 (polycystin 2, transient receptor potential cation channel [Source:NCBI gene;Acc:100192346]) HSP 1 Score: 120.168 bits (300), Expect = 6.601e-27 Identity = 126/515 (24.47%), Postives = 230/515 (44.66%), Query Frame = 2 Query: 2771 NVQTYMDFYDWAQG-ILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISA-LVSKVYGNVPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLY--QNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTYAETIDENLFDYDKEMVDHVWNIFNEMMTGF--KSSMKYTVPDALKKKAIVPVDMSDVDMQFASKEN 4297 ++ T DF+ + QG L Y +VWYNN + G+ + + + G R+RQ+RV TC+I L +V G C Y +ED F + N + W + T++ +NA + Q + GG ++ L +E++ ++ L+ + WLD+ TRAIF + +VYNGN NL ++L E P +GG+ + + ++ RL Y+ + + ++ + L V+ + E+ ++ + YF + WN +++L + LS+ II + R + + + L N + SFD + + + F +++ K++ FNK +S + T+ R L MF +A+ + ++F F+ S + F + + + ++ E P +Y+ + F + ++F+ I+NDTY+E + ++ + EM MT F K K V LKK + D+SD Q K N Sbjct: 214 SLSTMEDFWKYTQGPFLGGMYWEVWYNNQSLPGN--QSFIYYENILLGVPRLRQVRVHNETCSIHEDLRDEVQG---CYGVYTPSNEDNSPFGPQ-----------NGTAW----VHTTESKMNASTHWGQVSKYGGGGYYQ-------------DLSRTREESGLQLQFLKDHLWLDRGTRAIFLDFSVYNGNVNLVCIARLLVEFPATGGV-LTSWQFQTVRLIKYVSSWDYFVGVCEVAFCLFVLYYVVEEVLEIHIHRLHYFKNLWNCLDVLIVTLSVVAIIMSITRAAMGGDLLKGLE-NYTSHTSFDSLANLQVQFNNMAAVIVFFCWVKLFKFINFNKTMSQLSTTMSRCAKDLVGFAIMFFIIFLAYAQLAYLVFGTQVNDFSTFQGSVFTQFRIILGDFDFFEIKEANPVL-GPIYFITFVLFIFFILMNMFLAIINDTYSE-VKADMAQHRSEM----------EMTDFIKKGCTKALVKLRLKKTTV--DDISDSLRQAGGKLN 679
BLAST of PKD1L-2 vs. Ensembl Medaka
Match: pkd2 (polycystin 2, transient receptor potential cation channel [Source:NCBI gene;Acc:100192346]) HSP 1 Score: 119.398 bits (298), Expect = 1.452e-26 Identity = 126/515 (24.47%), Postives = 230/515 (44.66%), Query Frame = 2 Query: 2771 NVQTYMDFYDWAQG-ILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISA-LVSKVYGNVPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLY--QNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTYAETIDENLFDYDKEMVDHVWNIFNEMMTGF--KSSMKYTVPDALKKKAIVPVDMSDVDMQFASKEN 4297 ++ T DF+ + QG L Y +VWYNN + G+ + + + G R+RQ+RV TC+I L +V G C Y +ED F + N + W + T++ +NA + Q + GG ++ L +E++ ++ L+ + WLD+ TRAIF + +VYNGN NL ++L E P +GG+ + + ++ RL Y+ + + ++ + L V+ + E+ ++ + YF + WN +++L + LS+ II + R + + + L N + SFD + + + F +++ K++ FNK +S + T+ R L MF +A+ + ++F F+ S + F + + + ++ E P +Y+ + F + ++F+ I+NDTY+E + ++ + EM MT F K K V LKK + D+SD Q K N Sbjct: 214 SLSTMEDFWKYTQGPFLGGMYWEVWYNNQSLPGN--QSFIYYENILLGVPRLRQVRVHNETCSIHEDLRDEVQG---CYGVYTPSNEDNSPFGPQ-----------NGTAW----VHTTESKMNASTHWGQVSKYGGGGYYQ-------------DLSRTREESGLQLQFLKDHLWLDRGTRAIFLDFSVYNGNVNLVCIARLLVEFPATGGV-LTSWQFQTVRLIKYVSSWDYFVGVCEVAFCLFVLYYVVEEVLEIHIHRLHYFKNLWNCLDVLIVTLSVVAIIMSITRAAMGGDLLKGLE-NYTSHTSFDSLANLQVQFNNMAAVIVFFCWVKLFKFINFNKTMSQLSTTMSRCAKDLVGFAIMFFIIFLAYAQLAYLVFGTQVNDFSTFQGSVFTQFRIILGDFDFFEIKEANPVL-GPIYFITFVLFIFFILMNMFLAIINDTYSE-VKADMAQHRSEM----------EMTDFIKKGCTKALVKLRLKKTTV--DDISDSLRQAGGKLN 679
BLAST of PKD1L-2 vs. Planmine SMEST
Match: SMESG000014723.1 (SMESG000014723.1) HSP 1 Score: 2066.58 bits (5353), Expect = 0.000e+0 Identity = 1085/1094 (99.18%), Postives = 1089/1094 (99.54%), Query Frame = 2 Query: 1346 MIDFKNVFANFASLLANSXXXXXXXXXXXXXXXXXXXXMWRKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVLLEIKRDEKFQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTGIISVLITYPCIFIASEIFXXXXXXXXXXXEDQEAKMKKMFLLPKGFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPIILLIIFVLAKKLLGAVSTDQEANIDEFVKDDLKKVLGANLNPPDQEKLEKIKKDKASGQRLSRVVGXXXXXXXXXXXXXXXXXXXRSQVTFDQTKMIRSRFIKSNVQTYMDFYDWAQGILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISALVSKVYGNVPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTYAETIDENLFDYDKEMVDHVWNIFNEMMTGFKSSMKYTVPDALKKKAIVPVDMSDVDMQFASKENIRNMVSKRVNPSLRRKLADLNGEKYKTEKRENKPNSENDVYINPISFTDIKVAATGSQILDDKTFAERLPKYRAKQNAVDTNNQPPSYMEPVRPLKPNPKIDLFSKTERK 4627 MIDFKNVFANFASLLANSYVVLIVIILIFILYLLLVIVMWRKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVLLEIKRDEKFQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTG+ISVLITYPCIFIASEIFRRTRRWKRRWTEDQEAKMKKMFLLPKGFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPIILLIIFVLAKKLLGAVSTDQEANIDEFVKDDLKKVLGANLNPPDQEKLEKIKKDKASGQRLSRVVGDALTYVLSLLLLTALAYDARSQVTFDQTKMIRSRFIKSNVQTYMDFYDWAQGILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCT+SALVSKVYGNVPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFGIYGGGGYIASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVELLSIFLSLSIIICTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTYAETIDENLFDYDKEMVDHVWNIFNEMMTGFKSSMKYTVPDALKKKAIVPVDMSDVDMQFASKENIRNMVSKRVNPSLRRKLADLNGEKYKTEKRENKPNSENDVYINPISFTDIKVAATGSQILDDKTFAERLPKYRAKQNAVDTNNQPPSYMEPVRPLKPNPKID + +K Sbjct: 1 MIDFKNVFANFASLLANSYVVLIVIILIFILYLLLVIVMWRKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVLLEIKRDEKFQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTGMISVLITYPCIFIASEIFRRTRRWKRRWTEDQEAKMKKMFLLPKGFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPIILLIIFVLAKKLLGAVSTDQEANIDEFVKDDLKKVLGANLNPPDQEKLEKIKKDKASGQRLSRVVGDALTYVLSLLLLTALAYDARSQVTFDQTKMIRSRFIKSNVQTYMDFYDWAQGILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTVSALVSKVYGNVPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFGIYGGGGYIASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVELLSIFLSLSIIICTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTYAETIDENLFDYDKEMVDHVWNIFNEMMTGFKSSMKYTVPDALKKKAIVPVDMSDVDMQFASKENIRNMVSKRVNPSLRRKLADLNGEKYKTEKRENKPNSENDVYINPISFTDIKVAATGSQILDDKTFAERLPKYRAKQNAVDTNNQPPSYMEPVRPLKPNPKIDYILQNRKK 1094
BLAST of PKD1L-2 vs. Planmine SMEST
Match: SMESG000014723.1 (SMESG000014723.1) HSP 1 Score: 2040.77 bits (5286), Expect = 0.000e+0 Identity = 1047/1056 (99.15%), Postives = 1051/1056 (99.53%), Query Frame = 2 Query: 1460 MWRKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVLLEIKRDEKFQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTGIISVLITYPCIFIASEIFXXXXXXXXXXXEDQEAKMKKMFLLPKGFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPIILLIIFVLAKKLLGAVSTDQEANIDEFVKDDLKKVLGANLNPPDQEKLEKIKKDKASGQRLSRVVGXXXXXXXXXXXXXXXXXXXRSQVTFDQTKMIRSRFIKSNVQTYMDFYDWAQGILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISALVSKVYGNVPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTYAETIDENLFDYDKEMVDHVWNIFNEMMTGFKSSMKYTVPDALKKKAIVPVDMSDVDMQFASKENIRNMVSKRVNPSLRRKLADLNGEKYKTEKRENKPNSENDVYINPISFTDIKVAATGSQILDDKTFAERLPKYRAKQNAVDTNNQPPSYMEPVRPLKPNPKIDLFSKTERK 4627 MWRKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVLLEIKRDEKFQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTG+ISVLITYPCIFIASEIFRRTRRWKRRWTEDQEAKMKKMFLLPKGFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPIILLIIFVLAKKLLGAVSTDQEANIDEFVKDDLKKVLGANLNPPDQEKLEKIKKDKASGQRLSRVVGDALTYVLSLLLLTALAYDARSQVTFDQTKMIRSRFIKSNVQTYMDFYDWAQGILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCT+SALVSKVYGNVPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFGIYGGGGYIASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVELLSIFLSLSIIICTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTYAETIDENLFDYDKEMVDHVWNIFNEMMTGFKSSMKYTVPDALKKKAIVPVDMSDVDMQFASKENIRNMVSKRVNPSLRRKLADLNGEKYKTEKRENKPNSENDVYINPISFTDIKVAATGSQILDDKTFAERLPKYRAKQNAVDTNNQPPSYMEPVRPLKPNPKID + +K Sbjct: 1 MWRKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSSGIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVLLEIKRDEKFQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTGMISVLITYPCIFIASEIFRRTRRWKRRWTEDQEAKMKKMFLLPKGFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPIILLIIFVLAKKLLGAVSTDQEANIDEFVKDDLKKVLGANLNPPDQEKLEKIKKDKASGQRLSRVVGDALTYVLSLLLLTALAYDARSQVTFDQTKMIRSRFIKSNVQTYMDFYDWAQGILNESYPKVWYNNMNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTVSALVSKVYGNVPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFGIYGGGGYIASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVLLLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVELLSIFLSLSIIICTAVRIMVTINAITMLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTYAETIDENLFDYDKEMVDHVWNIFNEMMTGFKSSMKYTVPDALKKKAIVPVDMSDVDMQFASKENIRNMVSKRVNPSLRRKLADLNGEKYKTEKRENKPNSENDVYINPISFTDIKVAATGSQILDDKTFAERLPKYRAKQNAVDTNNQPPSYMEPVRPLKPNPKIDYILQNRKK 1056
BLAST of PKD1L-2 vs. Planmine SMEST
Match: SMESG000014725.1 (SMESG000014725.1) HSP 1 Score: 530.406 bits (1365), Expect = 0.000e+0 Identity = 326/327 (99.69%), Postives = 327/327 (100.00%), Query Frame = 3 Query: 81 IMQRSRLCNNPAPSNAGQDCSGLSTDTQSCTNVPLNCPVNGMXXXXXXXXXXXXXXXXXXXXXXXNCDNPSPLNGGLGCSSCVTVIFGSCGMSDINVENCTWISCSDPQLVAQNIISDTLSKLNISGTNSTMSVQQTMNLAFDVVNKIQSALQNALLNSTGPLMIQTNEVTVGLQSLSPTSGQQNISMVSTDKGKISIGSSLNLTTPTVVTXXXXXXXXXXXXXXXXXXXXXMLSLTIQNVSNTTPVQLSVSIPNSNQQVESDMLSPVKFNVSNQLIQTLQYTSLSTVYKLSMNLSNATDFTIFFSASSLANTTDSSDAFIYLSNQL 1061 IMQRSRLCNNPAPSNAGQDCSGLSTDTQSCTNVPLNCPVNGMWSSWSTWSSCSSSCGFGTRSRTRNCDNPSPLNGGLGCSSCVTVIFGSCGMSDINVENCTWISCSDPQLVAQNIISDTLSKLNISGTNSTMSVQQTMNLAFDVVNKIQSALQNALLNSTGPLMIQTNEVTVGLQSLSPTSGQQNISMVSTDKGKISIGSSLNLTTPTVVTFSALKSSVFFSASSVADTSAAMLSLTIQNVSNTTPVQLSVSIPNSNQQVESDMLSPVKFNVSNQLIQTLQYTSLSTVYKLSMNLSNATDFTIFFSASSLANTTDSSDAFIYLSNQ+ Sbjct: 398 IMQRSRLCNNPAPSNAGQDCSGLSTDTQSCTNVPLNCPVNGMWSSWSTWSSCSSSCGFGTRSRTRNCDNPSPLNGGLGCSSCVTVIFGSCGMSDINVENCTWISCSDPQLVAQNIISDTLSKLNISGTNSTMSVQQTMNLAFDVVNKIQSALQNALLNSTGPLMIQTNEVTVGLQSLSPTSGQQNISMVSTDKGKISIGSSLNLTTPTVVTFSALKSSVFFSASSVADTSAAMLSLTIQNVSNTTPVQLSVSIPNSNQQVESDMLSPVKFNVSNQLIQTLQYTSLSTVYKLSMNLSNATDFTIFFSASSLANTTDSSDAFIYLSNQV 724 HSP 2 Score: 136.346 bits (342), Expect = 0.000e+0 Identity = 67/69 (97.10%), Postives = 68/69 (98.55%), Query Frame = 2 Query: 1055 STSWDTSSGMLRITIPSGQVTPPNNMTLVMITSTNTTNGILLLSLGVASLTPRIWNFNMEVWQDFSASV 1261 S SWDTSSGMLRITIPSGQVTPPNNMTLVMITSTNTTNGILLLSLGVASLTPRIWNF+MEVWQDFSASV Sbjct: 735 SASWDTSSGMLRITIPSGQVTPPNNMTLVMITSTNTTNGILLLSLGVASLTPRIWNFDMEVWQDFSASV 803 HSP 3 Score: 93.2041 bits (230), Expect = 1.226e-18 Identity = 63/81 (77.78%), Postives = 66/81 (81.48%), Query Frame = 3 Query: 81 IMQRSRLCNNPAPSNAGQDCSGLSTDTQSCTNVPLNCPVNGMXXXXXXXXXXXXXXXXXXXXXXXN-CDNPSPLNGGLGCS 320 IMQRSRLCNNPAPSNAGQDCSGLSTDTQSCTNVPLNCPVNG WSSWSTWSSCS SCG + C+NP+P N G CS Sbjct: 278 IMQRSRLCNNPAPSNAGQDCSGLSTDTQSCTNVPLNCPVNGSWSSWSTWSSCSVSCGSNGIMQRSRLCNNPAPSNAGQDCS 358
BLAST of PKD1L-2 vs. Planmine SMEST
Match: SMESG000014725.1 (SMESG000014725.1) HSP 1 Score: 530.02 bits (1364), Expect = 0.000e+0 Identity = 326/327 (99.69%), Postives = 327/327 (100.00%), Query Frame = 3 Query: 81 IMQRSRLCNNPAPSNAGQDCSGLSTDTQSCTNVPLNCPVNGMXXXXXXXXXXXXXXXXXXXXXXXNCDNPSPLNGGLGCSSCVTVIFGSCGMSDINVENCTWISCSDPQLVAQNIISDTLSKLNISGTNSTMSVQQTMNLAFDVVNKIQSALQNALLNSTGPLMIQTNEVTVGLQSLSPTSGQQNISMVSTDKGKISIGSSLNLTTPTVVTXXXXXXXXXXXXXXXXXXXXXMLSLTIQNVSNTTPVQLSVSIPNSNQQVESDMLSPVKFNVSNQLIQTLQYTSLSTVYKLSMNLSNATDFTIFFSASSLANTTDSSDAFIYLSNQL 1061 IMQRSRLCNNPAPSNAGQDCSGLSTDTQSCTNVPLNCPVNGMWSSWSTWSSCSSSCGFGTRSRTRNCDNPSPLNGGLGCSSCVTVIFGSCGMSDINVENCTWISCSDPQLVAQNIISDTLSKLNISGTNSTMSVQQTMNLAFDVVNKIQSALQNALLNSTGPLMIQTNEVTVGLQSLSPTSGQQNISMVSTDKGKISIGSSLNLTTPTVVTFSALKSSVFFSASSVADTSAAMLSLTIQNVSNTTPVQLSVSIPNSNQQVESDMLSPVKFNVSNQLIQTLQYTSLSTVYKLSMNLSNATDFTIFFSASSLANTTDSSDAFIYLSNQ+ Sbjct: 396 IMQRSRLCNNPAPSNAGQDCSGLSTDTQSCTNVPLNCPVNGMWSSWSTWSSCSSSCGFGTRSRTRNCDNPSPLNGGLGCSSCVTVIFGSCGMSDINVENCTWISCSDPQLVAQNIISDTLSKLNISGTNSTMSVQQTMNLAFDVVNKIQSALQNALLNSTGPLMIQTNEVTVGLQSLSPTSGQQNISMVSTDKGKISIGSSLNLTTPTVVTFSALKSSVFFSASSVADTSAAMLSLTIQNVSNTTPVQLSVSIPNSNQQVESDMLSPVKFNVSNQLIQTLQYTSLSTVYKLSMNLSNATDFTIFFSASSLANTTDSSDAFIYLSNQV 722 HSP 2 Score: 136.346 bits (342), Expect = 0.000e+0 Identity = 67/69 (97.10%), Postives = 68/69 (98.55%), Query Frame = 2 Query: 1055 STSWDTSSGMLRITIPSGQVTPPNNMTLVMITSTNTTNGILLLSLGVASLTPRIWNFNMEVWQDFSASV 1261 S SWDTSSGMLRITIPSGQVTPPNNMTLVMITSTNTTNGILLLSLGVASLTPRIWNF+MEVWQDFSASV Sbjct: 733 SASWDTSSGMLRITIPSGQVTPPNNMTLVMITSTNTTNGILLLSLGVASLTPRIWNFDMEVWQDFSASV 801 HSP 3 Score: 92.8189 bits (229), Expect = 1.277e-18 Identity = 63/81 (77.78%), Postives = 66/81 (81.48%), Query Frame = 3 Query: 81 IMQRSRLCNNPAPSNAGQDCSGLSTDTQSCTNVPLNCPVNGMXXXXXXXXXXXXXXXXXXXXXXXN-CDNPSPLNGGLGCS 320 IMQRSRLCNNPAPSNAGQDCSGLSTDTQSCTNVPLNCPVNG WSSWSTWSSCS SCG + C+NP+P N G CS Sbjct: 276 IMQRSRLCNNPAPSNAGQDCSGLSTDTQSCTNVPLNCPVNGSWSSWSTWSSCSVSCGSNGIMQRSRLCNNPAPSNAGQDCS 356
BLAST of PKD1L-2 vs. Planmine SMEST
Match: SMESG000066980.1 (SMESG000066980.1) HSP 1 Score: 137.887 bits (346), Expect = 4.105e-32 Identity = 171/706 (24.22%), Postives = 298/706 (42.21%), Query Frame = 2 Query: 2252 EDQEAKMKKMFLLPKGFIFVGWSLLFVALVASVFFTFLYSLQWGGEKSNQWLQTFFVGIFGMVFLSDPI---ILLIIFVLAKKLLGAVSTDQEANIDEFVKDDL---------KKVLGANL------------NPPDQEKLEKIKKDKASGQRLSRVVGXXXXXXXXXXXXXXXXXXXRSQVTFDQTKMIRSRFIK-------SNVQTYMDFYDWAQGILNESYPK----VWYNN----------MNRTGDLTTAIAICDCLRQGPFRIRQIRVKRNTCTISALVSKVYGNVPCNENYNLLSEDTRSFSVKWTPLANSSVSFNDSNWNRNYLSPTQTVINAFLYQNNTISGGYPFEGTFXXXXXXXXXASLGMKQEQAAYIIRNLQANNWLDKLTRAIFFEGTVYNGNTNLFTTIQVLFEQPNSGGLRMFPYGVRSYRLYDYLPGNMIVL---------LLMQILYALTVVLNIYREIKKVCKQKKEYFSSNWNLVEXXXXXXXXXXXXCTAVRIMVTINAIT--MLNVNKGFYVSFDKATSWLETSCILMGISSFVSIIRVLKYMGFNKYISIMQGTIVRAYTQLSSLGFMFICFLIAFLTVGNILFSLNNVKFTNLLTSTVSLFGVFVAIVKYGDMFETPPAFDSALYYNVWSALSVFFITSVFICILNDTYA---ETIDENLFDYDKEMVDHVWNIFNEMMTG 4192 +++E + + L P W+ L L+ + T Y +Q+G +W+ + F+ F V L PI L I F L K A + DE + D+L ++ L L PP QE++EK ++ + ++ V+ + Y+ L ++Y R ++D +++ FIK +++ + F++W IL P+ VWYNN NR L G IRQ+R K+++C ++ V + + C Y++ ++D +S+ WT L S S SP FLY N + G P+ G Y GGGY+ L + L+ N W+D TRAIF E T +N N NLF + E P +GGL + +Y P N++ L + Q+LY + +++ + +EI+ KQK +YFS WN +EL I SL A + + N +T Y++F + W E L+ + F + I+ ++ + FNK I ++ + T + +F +AF+ + LF + ++ + L + S + + + ++++ P F ++ + VF + ++F+ IL + + E ID L D E++ ++ F M TG Sbjct: 2137 QEKETPVVRQKLFPWWMRIFAWTFLITLLIVASVLTTFYGIQFGDLACKKWISSMFISFFTSVLLVQPIKVICLAIFFALLCKDSSAFDVEYIGEEDE-IMDELGRRNAIMQNEEYLHQELYTAPIKPHKICFRPPSQEEIEKARELRLKELQMYDVIREVGFYLAFFCTLLFISYSLRHPDSYDLQNELKNVFIKQAPDSSFTDITSETLFWNW---ILLVFVPRIRAPVWYNNDPPIFQRGFISNRNNRLI-----------GYAIIRQVRSKKDSCKVNDYVKHLIKH--CYSQYDIFNQDEKSYGFGWTELNTSDTS----------ESP-------FLYSNESSLDGLPYIGRLSTYSGGGYVYKLKDDVNTLYNDLSALRDNKWIDFQTRAIFIEFTTFNPNINLFAIHTYVAEMPGNGGL---------WTIYRIEPANLLGLYSGGVKAFEIFCQVLYGIFILVIVVKEIRNFLKQKWKYFSQFWNFIELFIIIGSLLSAAGFAY-VTIATNKLTGKFSQYGGSVYLNFAQVAFWNEYFSYLVSLIIFCATIKFIRVLRFNKRIGMLGAVLSYTATDMKQFFIIFFIMFLAFVMMFYSLFMDSLYRYHSFLFAIESSMNIPLGKFGFLELYQKAPIFGPIVFAG-FVLFIVFVLLNMFVAILYNGFTVVKEDID--LQSSDHELMRFIFTKF-VMWTG 2794 HSP 2 Score: 107.842 bits (268), Expect = 6.445e-23 Identity = 86/310 (27.74%), Postives = 157/310 (50.65%), Query Frame = 2 Query: 1301 NFLGTFSAKIFIAPNMIDFKNVFANFASLLANSXXXXXXXXXXXXXXXXXXXXMWRKDRRESILLRYEPLLDNDPEYEYSYVISVHTGSCRNAGTSSDIFINLLGKWGSSGHRKMTDGYRDGLFETGTVCNFVMTTDSPLGDLMALRIWHNSS--GIKPSWNLEKLVIEDIQTNKMYIFMCETWLSDSKFDGNTERVLLEIKRDE--KFQNLFQRMKVSGVMDKHIIAGITNNTGVSCYTRVQKVTVFVTMFFLIMVSNAMFFGKDNNLSGDANFKIDFGLISITWFQFYTGIISVLITYPCIFIASEIF 2218 N L +FS+ +APN IDF +F+NF + + I I ++++LL++ R+D ++ + PL NDP+ Y Y + V T NAGT+S+++ L G+ + + D R + + G V F++ LG + +R+WH++S G SW L I D+QT + + F+ W + + DG +R++ +E FQ +F R + + + H+ I S +TRV++V + + FL M++ MF+ + +N + G +++ + +TG IS +I + +F+ E+F Sbjct: 1756 NHLTSFSSGWLVAPNAIDFNYIFSNFD--FTKNVTLFATEIAIAVVFILLLVWARRQDIKDIEKVGLTPLASNDPKDMYLYEVIVDTSIRNNAGTTSNVYFILSGELNETDPTHLVDSKRK-ILKRGNVDRFLLAVPRSLGAMQFIRLWHDNSGKGTNASWYCNCLGIIDLQTKEKFNFLVNKWFAVEEDDGQIDRIIPVAGINELLYFQEMFSRKMKANLSEDHLWLSIIARPPESRFTRVERVACCLLLLFLTMLTTCMFYQTEGPSKPVSNI-LTIGPFALSAKELWTGFISNIIAFVPLFVLIELF 2061 The following BLAST results are available for this feature:
BLAST of PKD1L-2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of PKD1L-2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 2
BLAST of PKD1L-2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 4
BLAST of PKD1L-2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of PKD1L-2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of PKD1L-2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of PKD1L-2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of PKD1L-2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of PKD1L-2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of PKD1L-2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of PKD1L-2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of PKD1L-2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of PKD1L-2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of PKD1L-2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30020654 ID=SMED30020654|Name=PKD1L-2|organism=Schmidtea mediterranea sexual|type=transcript|length=4753bpback to top protein sequence of SMED30020654-orf-1 >SMED30020654-orf-1 ID=SMED30020654-orf-1|Name=SMED30020654-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=364bp LNCPVNGSWSSWSTWSSCSVSCGSNGIMQRSRLCNNPAPSNAGQDCSGLSback to top protein sequence of SMED30020654-orf-2 >SMED30020654-orf-2 ID=SMED30020654-orf-2|Name=SMED30020654-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1196bp MLRITIPSGQVTPPNNMTLVMITSTNTTNGILLLSLGVASLTPRIWNFNMback to top Annotated Terms
The following terms have been associated with this transcript:
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