RRM domain-containing protein

Overview


Name	RRM domain-containing protein
Smed ID	SMED30020626
Length (bp)	2287

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of RRM domain-containing protein (SMED30020626) t-SNE clustered cells

Violin plots show distribution of expression levels for RRM domain-containing protein (SMED30020626) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of RRM domain-containing protein (SMED30020626) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for RRM domain-containing protein (SMED30020626) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30020626

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 23

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
intestinal phagocyte	SMED30020626	SMESG000018666.1	Contig3691	newmark_ests	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30020626	SMESG000018666.1	Contig3691	uc_Smed_v2	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30020626	SMESG000070758.1	Contig3691	newmark_ests	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30020626	SMESG000070758.1	Contig3691	uc_Smed_v2	PMID:23079596 Forsthoefel et al., 2012
X1 cell	SMED30020626	SMESG000018666.1	SmedASXL_015492	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X2 cell	SMED30020626	SMESG000018666.1	SmedASXL_015492	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X1 cell	SMED30020626	SMESG000018666.1	SmedASXL_015493	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X2 cell	SMED30020626	SMESG000018666.1	SmedASXL_015493	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
neoblast	SMED30020626	SMESG000018666.1 SMESG000018665.1	dd_Smed_v4_10611_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchyma	SMED30020626	SMESG000018666.1	CUFF.172807.1	be_Smed_v2	PMID:22543868 Onal et al., 2012
tail stripe	SMED30020626	SMESG000018666.1	CUFF.172807.1	be_Smed_v2	PMID:22543868 Onal et al., 2012
reproductive organ	SMED30020626	SMESG000018666.1	Contig32058	newmark_ests	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30020626	SMESG000018666.1	Contig32058	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30020626	SMESG000018666.1 SMESG000018665.1	Contig38356	newmark_ests	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30020626	SMESG000018666.1 SMESG000018665.1	Contig38356	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
ovary	SMED30020626	SMESG000018666.1	KU519616	smed_ncbi_20200123	PMID:27330085 Iyer et al., 2016
testis	SMED30020626	SMESG000018666.1	KU519616	smed_ncbi_20200123	PMID:27330085 Iyer et al., 2016
testis	SMED30020626	SMESG000018666.1	KU519616	smed_ncbi_20200123	PMID:27330085 Iyer et al., 2016
spermatogonium	SMED30020626	SMESG000018666.1	KU519616	smed_ncbi_20200123	PMID:27330085 Iyer et al., 2016
spermatocyte	SMED30020626	SMESG000018666.1	KU519616	smed_ncbi_20200123	PMID:27330085 Iyer et al., 2016
spermatid	SMED30020626	SMESG000018666.1	KU519616	smed_ncbi_20200123	PMID:27330085 Iyer et al., 2016
spermatogonial stem cell	SMED30020626	SMESG000018666.1	KU519616	smed_ncbi_20200123	PMID:27330085 Iyer et al., 2016
testis primordium	SMED30020626	SMESG000018666.1	Contig6439_SE3	GPL10652	PMID:20844018 Wang et al., 2010

Note: Hover over icons to view figure legend

Homology

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BLAST of RRM domain-containing protein vs. Ensembl Human
Match: BOLL (boule homolog, RNA binding protein [Source:HGNC Symbol;Acc:HGNC:14273])

HSP 1 Score: 132.494 bits (332), Expect = 1.131e-33
Identity = 83/174 (47.70%), Postives = 108/174 (62.07%), Query Frame = 2

Query:  251 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHL-FPRQEI---SGTVLYNGPV--PYALQNGLTLFQVPGQDYSV---LASQSPQYATMMLPQPTTAMYLPQPQYAYQTPTAVIP 745
            P+ GT+IPNRIFVGGI   T E +L+ FFS YG +K+VKI+NDR G+SKG YGFVTFE QE A+KI++ EAE L +K++KLNIG A+RKQ +  PR  I   +GT+        PY   NG+  F  P +  SV     S+S   + +M+ QP       QP Y YQ  T  +P
Sbjct:   25 PRYGTVIPNRIFVGGIDFKTNESDLRKFFSQYGSVKEVKIVNDRAGVSKG-YGFVTFETQEDAQKILQ-EAEKLNYKDKKLNIGPAIRKQQVGIPRSSIMPAAGTMYLTTSTGYPYTYHNGVAYFHTP-EVTSVPPPWPSRSVCSSPVMVAQPIYQ----QPAYHYQATTQYLP 191

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Query:  251 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHL-FPRQEI---SGTVLYNGPV--PYALQNGLTLFQVPGQDYSV---LASQSPQYATMMLPQPTTAMYLPQPQYAYQTPTAVIP 745
            P+ GT+IPNRIFVGGI   T E +L+ FFS YG +K+VKI+NDR G+SKG YGFVTFE QE A+KI++ EAE L +K++KLNIG A+RKQ +  PR  I   +GT+        PY   NG+  F  P +  SV     S+S   + +M+ QP       QP Y YQ  T  +P
Sbjct:   25 PRYGTVIPNRIFVGGIDFKTNESDLRKFFSQYGSVKEVKIVNDRAGVSKG-YGFVTFETQEDAQKILQ-EAEKLNYKDKKLNIGPAIRKQQVGIPRSSIMPAAGTMYLTTSTGYPYTYHNGVAYFHTP-EVTSVPPPWPSRSVCSSPVMVAQPIYQ----QPAYHYQATTQYLP 191

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Human
Match: BOLL (boule homolog, RNA binding protein [Source:HGNC Symbol;Acc:HGNC:14273])

HSP 1 Score: 132.494 bits (332), Expect = 1.277e-33
Identity = 83/174 (47.70%), Postives = 108/174 (62.07%), Query Frame = 2

Query:  251 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHL-FPRQEI---SGTVLYNGPV--PYALQNGLTLFQVPGQDYSV---LASQSPQYATMMLPQPTTAMYLPQPQYAYQTPTAVIP 745
            P+ GT+IPNRIFVGGI   T E +L+ FFS YG +K+VKI+NDR G+SKG YGFVTFE QE A+KI++ EAE L +K++KLNIG A+RKQ +  PR  I   +GT+        PY   NG+  F  P +  SV     S+S   + +M+ QP       QP Y YQ  T  +P
Sbjct:   37 PRYGTVIPNRIFVGGIDFKTNESDLRKFFSQYGSVKEVKIVNDRAGVSKG-YGFVTFETQEDAQKILQ-EAEKLNYKDKKLNIGPAIRKQQVGIPRSSIMPAAGTMYLTTSTGYPYTYHNGVAYFHTP-EVTSVPPPWPSRSVCSSPVMVAQPIYQ----QPAYHYQATTQYLP 203

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Human
Match: BOLL (boule homolog, RNA binding protein [Source:HGNC Symbol;Acc:HGNC:14273])

HSP 1 Score: 130.183 bits (326), Expect = 2.186e-32
Identity = 81/167 (48.50%), Postives = 105/167 (62.87%), Query Frame = 2

Query:  251 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHL-FPRQEI---SGTVLYNGPV--PYALQNGLTLFQVPGQDYSV---LASQSPQYATMMLPQPTTAMYLPQPQYAYQ 724
            P+ GT+IPNRIFVGGI   T E +L+ FFS YG +K+VKI+NDR G+SKG YGFVTFE QE A+KI++ EAE L +K++KLNIG A+RKQ +  PR  I   +GT+        PY   NG+  F  P +  SV     S+S   + +M+ QP       QP Y YQ
Sbjct:   25 PRYGTVIPNRIFVGGIDFKTNESDLRKFFSQYGSVKEVKIVNDRAGVSKG-YGFVTFETQEDAQKILQ-EAEKLNYKDKKLNIGPAIRKQQVGIPRSSIMPAAGTMYLTTSTGYPYTYHNGVAYFHTP-EVTSVPPPWPSRSVCSSPVMVAQPIYQ----QPAYHYQ 184

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BLAST of RRM domain-containing protein vs. Ensembl Human
Match: DAZL (deleted in azoospermia like [Source:HGNC Symbol;Acc:HGNC:2685])

HSP 1 Score: 92.8189 bits (229), Expect = 7.054e-21
Identity = 49/114 (42.98%), Postives = 71/114 (62.28%), Query Frame = 2

Query:  260 GTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHLFPRQEISGTVLYNGPVPYALQNGLT 601
            G ++PN +FVGGI     E E++ FF+ YG +K+VKII DRTG+SKG YGFV+F N    +KI++++     F  +KL +G A+RKQ+L         +++N P P   QN  T
Sbjct:   73 GKIMPNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKG-YGFVSFFNDVDVQKIVESQIN---FHGKKLKLGPAIRKQNLCAYHVQPRPLVFNHPPPPQFQNVWT 182

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BLAST of RRM domain-containing protein vs. Ensembl Celegans
Match: daz-1 (DAZ protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q20870])

HSP 1 Score: 93.2041 bits (230), Expect = 1.313e-19
Identity = 45/89 (50.56%), Postives = 60/89 (67.42%), Query Frame = 2

Query:  251 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRK 517
            P    LIPNRIFVGG  ++TTE EL+  F  +  +KDVK++    G SKG YGF+TFE ++ AE+I K   + L F+ RKLN+G A+RK
Sbjct:   58 PPTYELIPNRIFVGGFPTSTTETELREHFEKFFAVKDVKMVKSLDGQSKG-YGFITFETEDQAEEIRKLTPKQLEFRSRKLNLGPAIRK 145

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BLAST of RRM domain-containing protein vs. Ensembl Celegans
Match: sup-12 (SUPpressor [Source:UniProtKB/TrEMBL;Acc:O45189])

HSP 1 Score: 55.8398 bits (133), Expect = 2.904e-8
Identity = 33/112 (29.46%), Postives = 57/112 (50.89%), Query Frame = 2

Query:  278 RIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHLFPRQEISGTVLYNGPVPYALQNGL-TLFQ 610
            +IFVGG+  +T+++ L  +F  +G I++  +I DR       YGFVT +++ +AE+  K+    +  ++  +N+ +   K    PR  +    L  G V   L   L  LFQ
Sbjct:   36 KIFVGGLPYHTSDKTLHEYFEQFGDIEEAVVITDRNTQKSRGYGFVTMKDRASAERACKDPNPIIDGRKANVNLAYLGAK----PRTNVQLAALAAGQVQLPLTTQLQALFQ 143

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BLAST of RRM domain-containing protein vs. Ensembl Celegans
Match: sup-12 (SUPpressor [Source:UniProtKB/TrEMBL;Acc:O45189])

HSP 1 Score: 53.5286 bits (127), Expect = 3.407e-8
Identity = 33/112 (29.46%), Postives = 57/112 (50.89%), Query Frame = 2

Query:  278 RIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHLFPRQEISGTVLYNGPVPYALQNGL-TLFQ 610
            +IFVGG+  +T+++ L  +F  +G I++  +I DR       YGFVT +++ +AE+  K+    +  ++  +N+ +   K    PR  +    L  G V   L   L  LFQ
Sbjct:   36 KIFVGGLPYHTSDKTLHEYFEQFGDIEEAVVITDRNTQKSRGYGFVTMKDRASAERACKDPNPIIDGRKANVNLAYLGAK----PRTNVQLAALAAGQVQLPLTTQLQALFQ 143

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BLAST of RRM domain-containing protein vs. Ensembl Celegans
Match: msi-1 (MuSashI (Fly neural) family; Neural RNA-binding protein MSI-1 [Source:UniProtKB/TrEMBL;Acc:G5EFS2])

HSP 1 Score: 55.4546 bits (132), Expect = 6.244e-8
Identity = 19/59 (32.20%), Postives = 41/59 (69.49%), Query Frame = 2

Query:  278 RIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIK 454
            ++F+GG+++ +T E++K +F +YG ++D  ++ D+       +GFVTF++ E A+K+ +
Sbjct:  135 KVFIGGLSATSTLEDMKQYFETYGKVEDAMLMFDKATQRHRGFGFVTFDSDEVADKVCE 193

HSP 2 Score: 50.447 bits (119), Expect = 2.698e-6
Identity = 20/75 (26.67%), Postives = 41/75 (54.67%), Query Frame = 2

Query:  260 GTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKE 484
            G+  P ++F+GG++  TT E L+ +F  +G + +  ++ D        +GF+TF +  + +K++ N    L  K+
Sbjct:   40 GSQDPGKMFIGGLSWQTTAENLRDYFGRFGEVNECMVMRDPATKRARGFGFITFVDPSSVDKVLNNREHELDGKK 114

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BLAST of RRM domain-containing protein vs. Ensembl Celegans
Match: H28G03.1 (pep chromosome:WBcel235:X:5216363:5218418:1 gene:WBGene00019249.1 transcript:H28G03.1c.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:H28G03.1)

HSP 1 Score: 54.6842 bits (130), Expect = 1.389e-7
Identity = 33/114 (28.95%), Postives = 56/114 (49.12%), Query Frame = 2

Query:  278 RIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHLFPRQEISGTV----LYNGPVPYA--LQNGLT 601
            ++F+GG++ +TT+E+L  +FS +GP+ D  +I D        +GFVTF +  +AE  + +    L         G  V  +   PR+++S  +        P P    L NG+T
Sbjct:   70 KLFIGGLSHDTTDEQLGNYFSQWGPVVDAIVIRDPNTKHSRGFGFVTFASIFSAESAMNDRPHKL--------GGKTVDSKRAIPREQMSSMIPPPFFETDPAPGCKLLLNGIT 175

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BLAST of RRM domain-containing protein vs. Ensembl Fly
Match: bol (gene:FBgn0011206 transcript:FBtr0076538)

HSP 1 Score: 108.612 bits (270), Expect = 2.130e-26
Identity = 73/174 (41.95%), Postives = 103/174 (59.20%), Query Frame = 2

Query:  251 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHLFPRQEISGTVLYNGPVPYALQNGLTLFQVPGQDYSVLASQSPQYATMMLPQPTTAMYLPQPQYAYQTPTAVIPS--PNNGQQ 766
            PK GTLIPNRIFVGGI+ +TTE +L   FS+YG +K  KII DR G+SKG YGFVTFE ++ A++ ++ + E ++ ++RKLNI  A++KQ   P Q I  T   NG V Y       +  +P   ++  A+  P  A +    P +AM   QP Y Y +    +P+  P N Q+
Sbjct:   25 PKYGTLIPNRIFVGGISGDTTEADLTRVFSAYGTVKSTKIIVDRAGVSKG-YGFVTFETEQEAQR-LQADGECVVLRDRKLNIAPAIKKQP-NPLQSIVAT---NGAVYYTTTPPAPISNIPMDQFA--AAVYPPAAGVPAIYPPSAMQY-QPFYQYYSVPMNVPTIWPQNYQE 189

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Fly
Match: bol (gene:FBgn0011206 transcript:FBtr0344979)

HSP 1 Score: 108.612 bits (270), Expect = 2.130e-26
Identity = 73/174 (41.95%), Postives = 103/174 (59.20%), Query Frame = 2

Query:  251 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHLFPRQEISGTVLYNGPVPYALQNGLTLFQVPGQDYSVLASQSPQYATMMLPQPTTAMYLPQPQYAYQTPTAVIPS--PNNGQQ 766
            PK GTLIPNRIFVGGI+ +TTE +L   FS+YG +K  KII DR G+SKG YGFVTFE ++ A++ ++ + E ++ ++RKLNI  A++KQ   P Q I  T   NG V Y       +  +P   ++  A+  P  A +    P +AM   QP Y Y +    +P+  P N Q+
Sbjct:   25 PKYGTLIPNRIFVGGISGDTTEADLTRVFSAYGTVKSTKIIVDRAGVSKG-YGFVTFETEQEAQR-LQADGECVVLRDRKLNIAPAIKKQP-NPLQSIVAT---NGAVYYTTTPPAPISNIPMDQFA--AAVYPPAAGVPAIYPPSAMQY-QPFYQYYSVPMNVPTIWPQNYQE 189

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BLAST of RRM domain-containing protein vs. Ensembl Fly
Match: bol (gene:FBgn0011206 transcript:FBtr0076540)

HSP 1 Score: 108.612 bits (270), Expect = 2.130e-26
Identity = 73/174 (41.95%), Postives = 103/174 (59.20%), Query Frame = 2

Query:  251 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHLFPRQEISGTVLYNGPVPYALQNGLTLFQVPGQDYSVLASQSPQYATMMLPQPTTAMYLPQPQYAYQTPTAVIPS--PNNGQQ 766
            PK GTLIPNRIFVGGI+ +TTE +L   FS+YG +K  KII DR G+SKG YGFVTFE ++ A++ ++ + E ++ ++RKLNI  A++KQ   P Q I  T   NG V Y       +  +P   ++  A+  P  A +    P +AM   QP Y Y +    +P+  P N Q+
Sbjct:   25 PKYGTLIPNRIFVGGISGDTTEADLTRVFSAYGTVKSTKIIVDRAGVSKG-YGFVTFETEQEAQR-LQADGECVVLRDRKLNIAPAIKKQP-NPLQSIVAT---NGAVYYTTTPPAPISNIPMDQFA--AAVYPPAAGVPAIYPPSAMQY-QPFYQYYSVPMNVPTIWPQNYQE 189

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BLAST of RRM domain-containing protein vs. Ensembl Fly
Match: bol (gene:FBgn0011206 transcript:FBtr0076539)

HSP 1 Score: 107.457 bits (267), Expect = 2.477e-26
Identity = 73/173 (42.20%), Postives = 102/173 (58.96%), Query Frame = 2

Query:  251 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHLFPRQEISGTVLYNGPVPYALQNGLTLFQVPGQDYSVLASQSPQYATMMLPQPTTAMYLPQPQYAYQTPTAVIPS--PNNGQ 763
            PK GTLIPNRIFVGGI+ +TTE +L   FS+YG +K  KII DR G+SKG YGFVTFE ++ A++ ++ + E ++ ++RKLNI  A++KQ   P Q I  T   NG V Y       +  +P   ++  A+  P  A +    P +AM   QP Y Y +    +P+  P N Q
Sbjct:   25 PKYGTLIPNRIFVGGISGDTTEADLTRVFSAYGTVKSTKIIVDRAGVSKG-YGFVTFETEQEAQR-LQADGECVVLRDRKLNIAPAIKKQP-NPLQSIVAT---NGAVYYTTTPPAPISNIPMDQFA--AAVYPPAAGVPAIYPPSAMQY-QPFYQYYSVPMNVPTIWPQNYQ 188

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Fly
Match: bol (gene:FBgn0011206 transcript:FBtr0076541)

HSP 1 Score: 107.457 bits (267), Expect = 2.477e-26
Identity = 73/173 (42.20%), Postives = 102/173 (58.96%), Query Frame = 2

Query:  251 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHLFPRQEISGTVLYNGPVPYALQNGLTLFQVPGQDYSVLASQSPQYATMMLPQPTTAMYLPQPQYAYQTPTAVIPS--PNNGQ 763
            PK GTLIPNRIFVGGI+ +TTE +L   FS+YG +K  KII DR G+SKG YGFVTFE ++ A++ ++ + E ++ ++RKLNI  A++KQ   P Q I  T   NG V Y       +  +P   ++  A+  P  A +    P +AM   QP Y Y +    +P+  P N Q
Sbjct:   25 PKYGTLIPNRIFVGGISGDTTEADLTRVFSAYGTVKSTKIIVDRAGVSKG-YGFVTFETEQEAQR-LQADGECVVLRDRKLNIAPAIKKQP-NPLQSIVAT---NGAVYYTTTPPAPISNIPMDQFA--AAVYPPAAGVPAIYPPSAMQY-QPFYQYYSVPMNVPTIWPQNYQ 188

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Zebrafish
Match: dazl (deleted in azoospermia-like [Source:NCBI gene;Acc:58039])

HSP 1 Score: 72.7886 bits (177), Expect = 3.635e-14
Identity = 36/88 (40.91%), Postives = 52/88 (59.09%), Query Frame = 2

Query:  260 GTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQH 523
            G + PN +FVGGI     E E++ FF+ YG +K+VKII  R G+ KG YGFV F      + I+    + + FK +KL +G A+ K+ 
Sbjct:   25 GKMTPNTLFVGGIDMKVDENEIREFFAKYGSVKEVKIITYRGGICKG-YGFVYFSEDVDIQTIVD---QPISFKGKKLKLGPAIMKER 108

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Zebrafish
Match: dazl (deleted in azoospermia-like [Source:NCBI gene;Acc:58039])

HSP 1 Score: 72.7886 bits (177), Expect = 3.880e-14
Identity = 36/88 (40.91%), Postives = 52/88 (59.09%), Query Frame = 2

Query:  260 GTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQH 523
            G + PN +FVGGI     E E++ FF+ YG +K+VKII  R G+ KG YGFV F      + I+    + + FK +KL +G A+ K+ 
Sbjct:   25 GKMTPNTLFVGGIDMKVDENEIREFFAKYGSVKEVKIITYRGGICKG-YGFVYFSEDVDIQTIV----DPISFKGKKLKLGPAIMKER 107

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Zebrafish
Match: dazl (deleted in azoospermia-like [Source:NCBI gene;Acc:58039])

HSP 1 Score: 72.7886 bits (177), Expect = 4.643e-14
Identity = 36/88 (40.91%), Postives = 52/88 (59.09%), Query Frame = 2

Query:  260 GTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQH 523
            G + PN +FVGGI     E E++ FF+ YG +K+VKII  R G+ KG YGFV F      + I+    + + FK +KL +G A+ K+ 
Sbjct:   25 GKMTPNTLFVGGIDMKVDENEIREFFAKYGSVKEVKIITYRGGICKG-YGFVYFSEDVDIQTIVD---QPISFKGKKLKLGPAIMKER 108

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Zebrafish
Match: dazl (deleted in azoospermia-like [Source:NCBI gene;Acc:58039])

HSP 1 Score: 73.1738 bits (178), Expect = 5.213e-14
Identity = 36/88 (40.91%), Postives = 52/88 (59.09%), Query Frame = 2

Query:  260 GTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQH 523
            G + PN +FVGGI     E E++ FF+ YG +K+VKII  R G+ KG YGFV F      + I+    + + FK +KL +G A+ K+ 
Sbjct:   42 GKMTPNTLFVGGIDMKVDENEIREFFAKYGSVKEVKIITYRGGICKG-YGFVYFSEDVDIQTIVD---QPISFKGKKLKLGPAIMKER 125

[Close]

Query:  260 GTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQH 523
            G + PN +FVGGI     E E++ FF+ YG +K+VKII  R G+ KG YGFV F      + I+    + + FK +KL +G A+ K+ 
Sbjct:   42 GKMTPNTLFVGGIDMKVDENEIREFFAKYGSVKEVKIITYRGGICKG-YGFVYFSEDVDIQTIVD---QPISFKGKKLKLGPAIMKER 125

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Xenopus
Match: dazl (deleted in azoospermia-like [Source:NCBI gene;Acc:394676])

HSP 1 Score: 81.2629 bits (199), Expect = 2.934e-16
Identity = 40/86 (46.51%), Postives = 57/86 (66.28%), Query Frame = 2

Query:  260 GTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRK 517
            G +IPN +FVGGI     E  +   F  YG +KD+KII DRTG+SKG YGFV+F ++   +KI+K++   + F  +KL +G A+RK
Sbjct:   25 GKVIPNTVFVGGIDITMDEMAIGNLFEKYGKVKDLKIITDRTGVSKG-YGFVSFYDEVDVQKIVKSQ---INFHGKKLKLGPAIRK 106

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Xenopus
Match: deup1 (deuterosome assembly protein 1 [Source:Xenbase;Acc:XB-GENE-5961526])

HSP 1 Score: 61.2326 bits (147), Expect = 3.255e-9
Identity = 26/69 (37.68%), Postives = 43/69 (62.32%), Query Frame = 2

Query:  266 LIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETL 472
            L   +IFVGGI  +T E  L+ +F SYG I+ ++++ DR    K  + FVTF++ +T +KI+  +  T+
Sbjct:  115 LTVKKIFVGGIKEDTEEYHLRDYFQSYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTI 183

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Xenopus
Match: msi1 (musashi RNA binding protein 1 [Source:NCBI gene;Acc:496961])

HSP 1 Score: 59.3066 bits (142), Expect = 1.058e-8
Identity = 43/165 (26.06%), Postives = 73/165 (44.24%), Query Frame = 2

Query:  275 NRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHLFPRQEISGTVLYNGPVPY---ALQNGLTLFQVPGQDYSVLASQS-----PQYATMMLPQPTTAMYLPQPQYAYQTPTAVIP 745
             +IFVGG++ NTT E++K +F  +G + D  ++ D+T      +GFVTFE ++  EK+       +    + +    A  K+ + P   + G    +  +PY   A   G+ +   PG   +  AS+S     P Y T   P    A+      +     +  IP
Sbjct:   88 KKIFVGGLSVNTTVEDVKQYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFEGEDIVEKVCDIHFHEI--NNKMVECKKAQPKEVMSPTGSVRGR---SRVMPYGMDAFMLGIGMLGYPGFQAATYASRSYTGIAPGY-TYQFPGKFVALMSICSMFCMHCESCTIP 246

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Xenopus
Match: psd3 (pleckstrin and Sec7 domain containing 3 [Source:Xenbase;Acc:XB-GENE-6467528])

HSP 1 Score: 58.9214 bits (141), Expect = 1.186e-8
Identity = 25/63 (39.68%), Postives = 40/63 (63.49%), Query Frame = 2

Query:  266 LIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIK 454
            L   +IFVGGI  +T E  L+ +F  YG I+ ++I+ DR    K  + FVTFE+ ++ +KI++
Sbjct:  102 LTVKKIFVGGIKEDTEEHHLREYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFEDHDSVDKIVR 164

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Xenopus
Match: msi1 (musashi RNA binding protein 1 [Source:NCBI gene;Acc:496961])

HSP 1 Score: 58.5362 bits (140), Expect = 1.663e-8
Identity = 35/128 (27.34%), Postives = 62/128 (48.44%), Query Frame = 2

Query:  275 NRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHLFPRQEISGTVLYNGPVPYALQN---GLTLFQVPGQDYSVLASQS 649
             +IFVGG++ NTT E++K +F  +G + D  ++ D+T      +GFVTFE ++  EK+       +    + +    A  K+ + P   + G       +PY +     G+ +   PG   +  AS+S
Sbjct:  109 KKIFVGGLSVNTTVEDVKQYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFEGEDIVEKVCDIHFHEI--NNKMVECKKAQPKEVMSPTGSVRGRSRV---MPYGMDAFMLGIGMLGYPGFQAATYASRS 231

HSP 2 Score: 51.9878 bits (123), Expect = 2.232e-6
Identity = 24/83 (28.92%), Postives = 43/83 (51.81%), Query Frame = 2

Query:  272 PNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQ 520
            P ++F+GG++  TT+E L+ +FS +G +K+  ++ D        +GFVTF +Q   +K++      L  K     +    R Q
Sbjct:   19 PCKMFIGGLSWQTTQEGLREYFSHFGDVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQSRHELDSKTIDPKVAFPRRAQ 101

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Mouse
Match: Boll (boule homolog, RNA binding protein [Source:MGI Symbol;Acc:MGI:1922638])

HSP 1 Score: 130.568 bits (327), Expect = 2.942e-33
Identity = 79/173 (45.66%), Postives = 105/173 (60.69%), Query Frame = 2

Query:  251 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHL-FPRQEI---SGTVLYNGPV--PYALQNGLTLFQVPG--QDYSVLASQSPQYATMMLPQPTTAMYLPQPQYAYQTPTAVIP 745
            P+ GT+IPNRIFVGGI   T E +L+ FFS YG +K+VKI+NDR G+SKG YGF+TFE QE A+KI++ EAE L +K++KLNIG A+RKQ +  PR  +   +GT+        PY   NG+  F  P          S+S   + +M+ QP       QP Y YQ P   +P
Sbjct:   24 PRYGTVIPNRIFVGGIDFKTNENDLRKFFSQYGSVKEVKIVNDRAGVSKG-YGFITFETQEDAQKILQ-EAEKLNYKDKKLNIGPAIRKQQVGIPRSSLMPAAGTMYLTTSTGYPYTYHNGVAYFHTPEVTSVPPSWPSRSISSSPVMVAQPVYQ----QPAYHYQAPAQCLP 190

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Mouse
Match: Boll (boule homolog, RNA binding protein [Source:MGI Symbol;Acc:MGI:1922638])

HSP 1 Score: 130.954 bits (328), Expect = 2.942e-33
Identity = 79/173 (45.66%), Postives = 105/173 (60.69%), Query Frame = 2

Query:  251 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHL-FPRQEI---SGTVLYNGPV--PYALQNGLTLFQVPG--QDYSVLASQSPQYATMMLPQPTTAMYLPQPQYAYQTPTAVIP 745
            P+ GT+IPNRIFVGGI   T E +L+ FFS YG +K+VKI+NDR G+SKG YGF+TFE QE A+KI++ EAE L +K++KLNIG A+RKQ +  PR  +   +GT+        PY   NG+  F  P          S+S   + +M+ QP       QP Y YQ P   +P
Sbjct:   37 PRYGTVIPNRIFVGGIDFKTNENDLRKFFSQYGSVKEVKIVNDRAGVSKG-YGFITFETQEDAQKILQ-EAEKLNYKDKKLNIGPAIRKQQVGIPRSSLMPAAGTMYLTTSTGYPYTYHNGVAYFHTPEVTSVPPSWPSRSISSSPVMVAQPVYQ----QPAYHYQAPAQCLP 203

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Mouse
Match: Boll (boule homolog, RNA binding protein [Source:MGI Symbol;Acc:MGI:1922638])

HSP 1 Score: 120.168 bits (300), Expect = 2.119e-31
Identity = 59/96 (61.46%), Postives = 76/96 (79.17%), Query Frame = 2

Query:  251 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHL-FPR 535
            P+ GT+IPNRIFVGGI   T E +L+ FFS YG +K+VKI+NDR G+SKG YGF+TFE QE A+KI++ EAE L +K++KLNIG A+RKQ +  PR
Sbjct:   37 PRYGTVIPNRIFVGGIDFKTNENDLRKFFSQYGSVKEVKIVNDRAGVSKG-YGFITFETQEDAQKILQ-EAEKLNYKDKKLNIGPAIRKQQVGIPR 130

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Mouse
Match: Dazl (deleted in azoospermia-like [Source:MGI Symbol;Acc:MGI:1342328])

HSP 1 Score: 90.1225 bits (222), Expect = 2.676e-19
Identity = 43/89 (48.31%), Postives = 63/89 (70.79%), Query Frame = 2

Query:  260 GTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHL 526
            G ++PN +FVGGI     E E++ FF+ YG +K+VKII DRTG+SKG YGFV+F N    +KI++++   + F  +KL +G A+RKQ+L
Sbjct:   35 GKIMPNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKG-YGFVSFYNDVDVQKIVESQ---INFHGKKLKLGPAIRKQNL 119

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Mouse
Match: Dazl (deleted in azoospermia-like [Source:MGI Symbol;Acc:MGI:1342328])

HSP 1 Score: 87.0409 bits (214), Expect = 1.871e-18
Identity = 42/86 (48.84%), Postives = 61/86 (70.93%), Query Frame = 2

Query:  269 IPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHL 526
            +PN +FVGGI     E E++ FF+ YG +K+VKII DRTG+SKG YGFV+F N    +KI++++   + F  +KL +G A+RKQ+L
Sbjct:    1 MPNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKG-YGFVSFYNDVDVQKIVESQ---INFHGKKLKLGPAIRKQNL 82

[Close]

BLAST of RRM domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8N9W6|BOLL_HUMAN (Protein boule-like OS=Homo sapiens OX=9606 GN=BOLL PE=1 SV=2)

HSP 1 Score: 132.494 bits (332), Expect = 5.433e-33
Identity = 83/174 (47.70%), Postives = 108/174 (62.07%), Query Frame = 2

Query:  251 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHL-FPRQEI---SGTVLYNGPV--PYALQNGLTLFQVPGQDYSV---LASQSPQYATMMLPQPTTAMYLPQPQYAYQTPTAVIP 745
            P+ GT+IPNRIFVGGI   T E +L+ FFS YG +K+VKI+NDR G+SKG YGFVTFE QE A+KI++ EAE L +K++KLNIG A+RKQ +  PR  I   +GT+        PY   NG+  F  P +  SV     S+S   + +M+ QP       QP Y YQ  T  +P
Sbjct:   25 PRYGTVIPNRIFVGGIDFKTNESDLRKFFSQYGSVKEVKIVNDRAGVSKG-YGFVTFETQEDAQKILQ-EAEKLNYKDKKLNIGPAIRKQQVGIPRSSIMPAAGTMYLTTSTGYPYTYHNGVAYFHTP-EVTSVPPPWPSRSVCSSPVMVAQPIYQ----QPAYHYQATTQYLP 191

[Close]

BLAST of RRM domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8WP23|BOLL_MACFA (Protein boule-like OS=Macaca fascicularis OX=9541 GN=BOLL PE=2 SV=2)

HSP 1 Score: 130.568 bits (327), Expect = 2.411e-32
Identity = 82/174 (47.13%), Postives = 107/174 (61.49%), Query Frame = 2

Query:  251 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHL-FPRQEI---SGTVLYNGPV--PYALQNGLTLFQVPGQDYSV---LASQSPQYATMMLPQPTTAMYLPQPQYAYQTPTAVIP 745
            P+ GT+IPNRIFVGGI   T E +L+ FFS YG +K+VKI+NDR G+SKG YGFVTFE QE A+KI++ EAE L +K++KLNIG A+RKQ +  PR  I   +GT+        PY   NG+  F  P +  SV     S+S   + +M+ QP       QP Y YQ     +P
Sbjct:   25 PRYGTVIPNRIFVGGIDFKTNESDLRKFFSQYGSVKEVKIVNDRAGVSKG-YGFVTFETQEDAQKILQ-EAEKLNYKDKKLNIGPAIRKQQVGIPRSSIMPAAGTMYLTTSTGYPYTYHNGVAYFHTP-EVTSVPPPWPSRSVCSSPVMVAQPIYQ----QPAYHYQATAQYLP 191

[Close]

BLAST of RRM domain-containing protein vs. UniProt/SwissProt
Match: sp|Q924M5|BOLL_MOUSE (Protein boule-like OS=Mus musculus OX=10090 GN=Boll PE=1 SV=2)

HSP 1 Score: 130.568 bits (327), Expect = 2.412e-32
Identity = 79/173 (45.66%), Postives = 105/173 (60.69%), Query Frame = 2

Query:  251 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHL-FPRQEI---SGTVLYNGPV--PYALQNGLTLFQVPG--QDYSVLASQSPQYATMMLPQPTTAMYLPQPQYAYQTPTAVIP 745
            P+ GT+IPNRIFVGGI   T E +L+ FFS YG +K+VKI+NDR G+SKG YGF+TFE QE A+KI++ EAE L +K++KLNIG A+RKQ +  PR  +   +GT+        PY   NG+  F  P          S+S   + +M+ QP       QP Y YQ P   +P
Sbjct:   25 PRYGTVIPNRIFVGGIDFKTNENDLRKFFSQYGSVKEVKIVNDRAGVSKG-YGFITFETQEDAQKILQ-EAEKLNYKDKKLNIGPAIRKQQVGIPRSSLMPAAGTMYLTTSTGYPYTYHNGVAYFHTPEVTSVPPSWPSRSISSSPVMVAQPVYQ----QPAYHYQAPAQCLP 191

[Close]

BLAST of RRM domain-containing protein vs. UniProt/SwissProt
Match: sp|Q24207|BOULE_DROME (Protein boule OS=Drosophila melanogaster OX=7227 GN=bol PE=1 SV=1)

HSP 1 Score: 108.612 bits (270), Expect = 2.135e-25
Identity = 73/174 (41.95%), Postives = 103/174 (59.20%), Query Frame = 2

Query:  251 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHLFPRQEISGTVLYNGPVPYALQNGLTLFQVPGQDYSVLASQSPQYATMMLPQPTTAMYLPQPQYAYQTPTAVIPS--PNNGQQ 766
            PK GTLIPNRIFVGGI+ +TTE +L   FS+YG +K  KII DR G+SKG YGFVTFE ++ A++ ++ + E ++ ++RKLNI  A++KQ   P Q I  T   NG V Y       +  +P   ++  A+  P  A +    P +AM   QP Y Y +    +P+  P N Q+
Sbjct:   25 PKYGTLIPNRIFVGGISGDTTEADLTRVFSAYGTVKSTKIIVDRAGVSKG-YGFVTFETEQEAQR-LQADGECVVLRDRKLNIAPAIKKQP-NPLQSIVAT---NGAVYYTTTPPAPISNIPMDQFA--AAVYPPAAGVPAIYPPSAMQY-QPFYQYYSVPMNVPTIWPQNYQE 189

[Close]

BLAST of RRM domain-containing protein vs. UniProt/SwissProt
Match: sp|Q92904|DAZL_HUMAN (Deleted in azoospermia-like OS=Homo sapiens OX=9606 GN=DAZL PE=1 SV=1)

HSP 1 Score: 94.3597 bits (233), Expect = 7.822e-20
Identity = 62/158 (39.24%), Postives = 86/158 (54.43%), Query Frame = 2

Query:  260 GTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHLFPRQEISGTVLYNGPVPYALQNGLTLFQVPGQDYSVLASQSPQYATMMLPQPTTAMYLPQPQYAYQTPT 733
            G ++PN +FVGGI     E E++ FF+ YG +K+VKII DRTG+SKG YGFV+F N    +KI++++   + F  +KL +G A+RKQ+L         +++N P P   QN  T               +P   T M  QPTT M  P  QY    PT
Sbjct:   35 GKIMPNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKG-YGFVSFFNDVDVQKIVESQ---INFHGKKLKLGPAIRKQNLCAYHVQPRPLVFNHPPPPQFQNVWT---------------NPNTETYM--QPTTTMN-PITQYVQAYPT 170

[Close]

BLAST of RRM domain-containing protein vs. TrEMBL
Match: A0A172RVQ0 (Boule 1 RNA-binding protein OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 226.483 bits (576), Expect = 2.737e-66
Identity = 124/129 (96.12%), Postives = 125/129 (96.90%), Query Frame = 2

Query:  149 STDSQLTPKVDTLAQEFQVSLXXXXXXXXXXXXXPKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHLFPR 535
            STDSQLTPKVDTLAQEFQVSLAAVNQATMTAAANPKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQ    +
Sbjct:   12 STDSQLTPKVDTLAQEFQVSLAAVNQATMTAAANPKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQKFLEQ 140

[Close]

BLAST of RRM domain-containing protein vs. TrEMBL
Match: A0A4S2M8S9 (RRM domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_001898 PE=4 SV=1)

HSP 1 Score: 225.328 bits (573), Expect = 2.515e-61
Identity = 110/177 (62.15%), Postives = 137/177 (77.40%), Query Frame = 2

Query:  251 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHLFPRQEISGTVLY-NGPVPYALQNGLTLFQVPGQDYSVLASQSPQYATMMLPQP--TTAMYLPQPQYAYQTPTAVIPSPNNGQQVT 772
            PK GTLIPNRIFVGGI SNTTE+ELK FFSS+G +KDVKII+DR G+SKGSYGFVTFE+QE AEKIIKNE+ETLIFK+RKLNIGHA+RKQ +FPR ++   + +  G +PY++QNG+ +F +PGQ+Y +L   +  YATMMLPQP   T +YLP    A  +P A +    + QQVT
Sbjct:   37 PKFGTLIPNRIFVGGIPSNTTEQELKSFFSSFGQVKDVKIISDRLGVSKGSYGFVTFESQEMAEKIIKNESETLIFKDRKLNIGHAIRKQQMFPRADLPAALFFAGGAMPYSIQNGMAVFSLPGQEYPMLTQATAPYATMMLPQPGGGTTLYLPSAASATASPYAQL----SQQQVT 209

[Close]

BLAST of RRM domain-containing protein vs. TrEMBL
Match: A0A419QF17 (Protein boule-like OS=Clonorchis sinensis OX=79923 GN=BOLL PE=4 SV=1)

HSP 1 Score: 226.868 bits (577), Expect = 8.505e-61
Identity = 110/177 (62.15%), Postives = 137/177 (77.40%), Query Frame = 2

Query:  251 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHLFPRQEISGTVLY-NGPVPYALQNGLTLFQVPGQDYSVLASQSPQYATMMLPQP--TTAMYLPQPQYAYQTPTAVIPSPNNGQQVT 772
            PK GTLIPNRIFVGGI SNTTE+ELK FFSS+G +KDVKII+DR G+SKGSYGFVTFE+QE AEKIIKNE+ETLIFK+RKLNIGHA+RKQ +FPR ++   + +  G +PY++QNG+ +F +PGQ+Y +L   +  YATMMLPQP   T +YLP    A  +P A +    + QQVT
Sbjct:   37 PKFGTLIPNRIFVGGIPSNTTEQELKSFFSSFGQVKDVKIISDRLGVSKGSYGFVTFESQEMAEKIIKNESETLIFKDRKLNIGHAIRKQQMFPRADLPAALFFAGGAMPYSIQNGMAVFSLPGQEYPMLTQATAPYATMMLPQPGGGTTLYLPSAASATASPYAQL----SQQQVT 209

[Close]

BLAST of RRM domain-containing protein vs. TrEMBL
Match: A0A075AGA8 (RRM domain-containing protein (Fragment) OS=Opisthorchis viverrini OX=6198 GN=T265_13550 PE=4 SV=1)

HSP 1 Score: 226.483 bits (576), Expect = 9.672e-61
Identity = 110/177 (62.15%), Postives = 137/177 (77.40%), Query Frame = 2

Query:  251 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHLFPRQEISGTVLY-NGPVPYALQNGLTLFQVPGQDYSVLASQSPQYATMMLPQP--TTAMYLPQPQYAYQTPTAVIPSPNNGQQVT 772
            PK GTLIPNRIFVGGI SNTTE+ELK FFSS+G +KDVKII+DR G+SKGSYGFVTFE+QE AEKIIKNE+ETLIFK+RKLNIGHA+RKQ +FPR ++   + +  G +PY++QNG+ +F +PGQ+Y +L   +  YATMMLPQP   T +YLP    A  +P A +    + QQVT
Sbjct:    9 PKFGTLIPNRIFVGGIPSNTTEQELKSFFSSFGQVKDVKIISDRLGVSKGSYGFVTFESQEMAEKIIKNESETLIFKDRKLNIGHAIRKQQMFPRADLPAALFFAGGAMPYSIQNGMAVFSLPGQEYPMLTQATAPYATMMLPQPGGGTTLYLPSAASATASPYAQL----SQQQVT 181

[Close]

BLAST of RRM domain-containing protein vs. TrEMBL
Match: A0A4S2MEX8 (RRM domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_001898 PE=4 SV=1)

HSP 1 Score: 226.868 bits (577), Expect = 1.319e-60
Identity = 110/177 (62.15%), Postives = 137/177 (77.40%), Query Frame = 2

Query:  251 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHLFPRQEISGTVLY-NGPVPYALQNGLTLFQVPGQDYSVLASQSPQYATMMLPQP--TTAMYLPQPQYAYQTPTAVIPSPNNGQQVT 772
            PK GTLIPNRIFVGGI SNTTE+ELK FFSS+G +KDVKII+DR G+SKGSYGFVTFE+QE AEKIIKNE+ETLIFK+RKLNIGHA+RKQ +FPR ++   + +  G +PY++QNG+ +F +PGQ+Y +L   +  YATMMLPQP   T +YLP    A  +P A +    + QQVT
Sbjct:   37 PKFGTLIPNRIFVGGIPSNTTEQELKSFFSSFGQVKDVKIISDRLGVSKGSYGFVTFESQEMAEKIIKNESETLIFKDRKLNIGHAIRKQQMFPRADLPAALFFAGGAMPYSIQNGMAVFSLPGQEYPMLTQATAPYATMMLPQPGGGTTLYLPSAASATASPYAQL----SQQQVT 209

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BLAST of RRM domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000005184.2 (pep primary_assembly:Astyanax_mexicanus-2.0:10:7750630:7761219:-1 gene:ENSAMXG00000005058.2 transcript:ENSAMXT00000005184.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 115.161 bits (287), Expect = 2.569e-28
Identity = 67/187 (35.83%), Postives = 103/187 (55.08%), Query Frame = 2

Query:  260 GTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQ---HLFPRQEISGTVL-YNGPV-----------PYALQNGLTLFQVPGQDYSVLASQSPQY----------ATMMLPQPTTAMYLPQPQYAYQTPTAVIP 745
            GT+IPNRIFVGGI     E +L+ FFS YG I++V I+ DR G+SKG YGFVTFE QE A+KI+ ++A+ L F+++++N+G A RKQ   H     +  G+ + Y  P            PY   NG+  F  P  +     + SP +          +++M+    +++ +PQP +  Q  +  +P
Sbjct:   32 GTVIPNRIFVGGIGGKAKENDLRCFFSEYGVIREVNIVTDRDGISKG-YGFVTFETQEDAQKIL-HDADRLSFRDKRINVGQAFRKQLKGHYSYTADTQGSSMAYQAPFGTTYLTTPTGYPYTYHNGVAYFHTPEPN-----TLSPSHWHAPPHTMSGSSVMVTHSASSICIPQPYHNSQASSQYVP 211

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BLAST of RRM domain-containing protein vs. Ensembl Cavefish
Match: dazl (deleted in azoospermia like [Source:NCBI gene;Acc:103038434])

HSP 1 Score: 74.7146 bits (182), Expect = 9.738e-15
Identity = 37/88 (42.05%), Postives = 53/88 (60.23%), Query Frame = 2

Query:  260 GTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQH 523
            G L PN +FVGGI     E E++ FF+ YG +K+VKII  R G+ KG YGFV F      + I++ +   + FK +KL +G A+ K+ 
Sbjct:   26 GKLTPNTLFVGGIDMKVEENEIRDFFARYGAVKEVKIITYRGGICKG-YGFVYFSEDVDIQTIVEQQ---ISFKGKKLKLGPAIMKER 109

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BLAST of RRM domain-containing protein vs. Ensembl Cavefish
Match: msi2b (RNA-binding protein Musashi homolog 2 [Source:NCBI gene;Acc:103023867])

HSP 1 Score: 60.4622 bits (145), Expect = 2.764e-9
Identity = 30/94 (31.91%), Postives = 54/94 (57.45%), Query Frame = 2

Query:  251 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHLFP 532
            PK+ T    +IFVGG+++NT  E++K +F  +G ++D  ++ D+T      +GFVTFEN++  EK+ +     +    + +    A  K+ +FP
Sbjct:  103 PKMVTRT-KKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEI--NNKMVECKKAQPKEVMFP 193

HSP 2 Score: 51.2174 bits (121), Expect = 2.626e-6
Identity = 22/83 (26.51%), Postives = 43/83 (51.81%), Query Frame = 2

Query:  272 PNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQ 520
            P ++F+GG++  T+ + L+ +FS +G I++  ++ D T      +GFVTF +  + +K++      L  K     +    R Q
Sbjct:   20 PGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADAASVDKVLGQPHHELDSKTIDPKVAFPRRAQ 102

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BLAST of RRM domain-containing protein vs. Ensembl Cavefish
Match: msi2a (RNA-binding protein Musashi homolog 2-like [Source:NCBI gene;Acc:103045937])

HSP 1 Score: 60.4622 bits (145), Expect = 2.799e-9
Identity = 30/94 (31.91%), Postives = 54/94 (57.45%), Query Frame = 2

Query:  251 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHLFP 532
            PK+ T    +IFVGG+++NT  E++K +F  +G ++D  ++ D+T      +GFVTFEN++  EK+ +     +    + +    A  K+ +FP
Sbjct:  103 PKMVTRT-KKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEI--NNKMVECKKAQPKEVMFP 193

HSP 2 Score: 51.2174 bits (121), Expect = 2.455e-6
Identity = 22/83 (26.51%), Postives = 43/83 (51.81%), Query Frame = 2

Query:  272 PNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQ 520
            P ++F+GG++  T+ + L+ +FS +G I++  ++ D T      +GFVTF +  + +K++      L  K     +    R Q
Sbjct:   20 PGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADAASVDKVLAQPHHELDSKTIDPKVAFPRRAQ 102

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BLAST of RRM domain-containing protein vs. Ensembl Cavefish
Match: msi1 (musashi RNA-binding protein 1 [Source:ZFIN;Acc:ZDB-GENE-050320-86])

HSP 1 Score: 60.8474 bits (146), Expect = 2.868e-9
Identity = 27/68 (39.71%), Postives = 44/68 (64.71%), Query Frame = 2

Query:  251 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIK 454
            PK+ T    +IFVGG++ NTT E++K +F  +G + D  ++ D+T      +GFVTFEN++  EK+ +
Sbjct:  174 PKLVTRT-KKIFVGGLSVNTTIEDVKQYFDQFGKVDDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCE 240

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BLAST of RRM domain-containing protein vs. Ensembl Sea Lamprey
Match: BOLL (boule homolog, RNA binding protein [Source:HGNC Symbol;Acc:HGNC:14273])

HSP 1 Score: 139.813 bits (351), Expect = 4.663e-37
Identity = 78/170 (45.88%), Postives = 107/170 (62.94%), Query Frame = 2

Query:  251 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHL----FPRQEISGTVLYNGPV--PYALQNGLTLFQVPGQDYSVLASQSPQ----YATMMLPQPTTAMYLPQPQYAYQTP 730
            P+ GT+IPNRIFVGGI     E ELK +F+ +G +KDVKIINDR G+SKG YGFVTFE+QE A+K I+ EAE +++K++KLNIG A+RKQ +    FP    SG+++       P+   NG+  FQ P    ++     PQ    +  M++P P  +    QP Y+YQ P
Sbjct:   34 PRYGTVIPNRIFVGGIDFKVNEAELKKYFTQFGVVKDVKIINDRAGVSKG-YGFVTFESQEDAQK-IQQEAEKIMYKDKKLNIGPAIRKQQVGFPQFPLTPASGSMVLTTSTGQPFLFHNGVAYFQQPD---AMPVQMPPQTYYSHQPMLIPSPQASPVFQQPAYSYQAP 198

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BLAST of RRM domain-containing protein vs. Ensembl Sea Lamprey
Match: HNRNPA0 (heterogeneous nuclear ribonucleoprotein A0 [Source:HGNC Symbol;Acc:HGNC:5030])

HSP 1 Score: 63.1586 bits (152), Expect = 7.686e-11
Identity = 30/87 (34.48%), Postives = 49/87 (56.32%), Query Frame = 2

Query:  266 LIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHL 526
            L   +IFVGGI  NT E+ L+ +FS YG ++ V ++ DR    K  +GFVTF + +  +K++  +  T+     K  +  A+ KQ +
Sbjct:  121 LKVKKIFVGGIKDNTDEDHLRDYFSEYGMVESVDVMEDRQSGKKRGFGFVTFSDHDAVDKVVVQKYHTI--NGHKAEVRKALSKQEM 205

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Sea Lamprey
Match: HNRNPA0 (heterogeneous nuclear ribonucleoprotein A0 [Source:HGNC Symbol;Acc:HGNC:5030])

HSP 1 Score: 60.077 bits (144), Expect = 2.113e-10
Identity = 25/69 (36.23%), Postives = 43/69 (62.32%), Query Frame = 2

Query:  266 LIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETL 472
            L   +IFVGGI  +T E+ L+ +F  YG ++  +++ DR+   K  +GFVTF + +T +K+I  +  T+
Sbjct:   97 LKVKKIFVGGIRDDTDEQHLREYFQVYGDVEAAEVMEDRSTGKKRGFGFVTFSDHDTVDKVIVQKYHTI 165

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BLAST of RRM domain-containing protein vs. Ensembl Sea Lamprey
Match: rbm24a (RNA binding motif protein 24a [Source:NCBI gene;Acc:405801])

HSP 1 Score: 59.6918 bits (143), Expect = 4.108e-10
Identity = 30/75 (40.00%), Postives = 47/75 (62.67%), Query Frame = 2

Query:  278 RIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDR-TGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNI 499
            +IFVGG+  +TT+  L+ FF ++G I +  +I DR +G S+G YGFVT  ++ +AE+  K+     I   RK N+
Sbjct:   13 KIFVGGLPYHTTDASLRAFFEAFGEIDEAVVITDRQSGKSRG-YGFVTMADRASAERACKD--PNPIIDGRKANV 84

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Sea Lamprey
Match: rbmx (RNA binding motif protein X-linked [Source:NCBI gene;Acc:321860])

HSP 1 Score: 60.8474 bits (146), Expect = 5.143e-10
Identity = 33/87 (37.93%), Postives = 52/87 (59.77%), Query Frame = 2

Query:  257 IGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDR-TGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVR 514
            +G   P ++FVGG+  +TTE+ L+  FS YG + DV ++ DR T LS+G + FVTF N E A K  + +A   + + R + +  A +
Sbjct:    1 MGEADPGKLFVGGLNIDTTEKALEATFSKYGRVADVLLMKDRETNLSRG-FAFVTFANPEDA-KEAERDANGKVLEGRAMRVDQATK 85

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Yeast
Match: HRP1 (Subunit of cleavage factor I; cleavage factor I is a five-subunit complex required for the cleavage and polyadenylation of pre-mRNA 3' ends; RRM-containing heteronuclear RNA binding protein and hnRNPA/B family member that binds to poly (A) signal sequences; required for genome stability [Source:SGD;Acc:S000005483])

HSP 1 Score: 57.3806 bits (137), Expect = 5.111e-9
Identity = 29/78 (37.18%), Postives = 52/78 (66.67%), Query Frame = 2

Query:  278 RIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDR-TGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHA 508
            +IFVGGI  +   +E + FFS +G I D +++ D+ TG S+G +GFVT+++ +  +++ +N+   + FK+RK+ I  A
Sbjct:  244 KIFVGGIGPDVRPKEFEEFFSQWGTIIDAQLMLDKDTGQSRG-FGFVTYDSADAVDRVCQNKF--IDFKDRKIEIKRA 318

HSP 2 Score: 55.0694 bits (131), Expect = 2.438e-8
Identity = 23/60 (38.33%), Postives = 43/60 (71.67%), Query Frame = 2

Query:  278 RIFVGGITSNTTEEELKIFFSSYGPIKDVKIIND-RTGLSKGSYGFVTFENQETAEKIIK 454
            ++F+GG+  +TTE+ L+ +F  YG + D+KI+ D  TG S+G +GF++FE   + ++++K
Sbjct:  160 KMFIGGLNWDTTEDNLREYFGKYGTVTDLKIMKDPATGRSRG-FGFLSFEKPSSVDEVVK 218

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Yeast
Match: NAM8 (RNA binding protein, component of the U1 snRNP protein; mutants are defective in meiotic recombination and in formation of viable spores, involved in the formation of DSBs through meiosis-specific splicing of REC107 pre-mRNA; Nam8p regulon embraces the meiotic pre-mRNAs of REC107, HFM1, AMA1 SPO22 and PCH2; the putative RNA binding domains RRM2 and RRM3 are required for Nam8p meiotic function [Source:SGD;Acc:S000001128])

HSP 1 Score: 50.447 bits (119), Expect = 6.892e-7
Identity = 33/97 (34.02%), Postives = 53/97 (54.64%), Query Frame = 2

Query:  281 IFVGGITSNTTEEEL-KIFFSSYGPIKDVKIINDR-TGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHLFPRQEISGTVLYN 565
            IFVG +  N TE +L ++F + Y      KI++D+ TG+SKG YGFV F N +  +++  +E + +    R + +G    +Q     Q +SG   YN
Sbjct:  165 IFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKG-YGFVKFTNSD-EQQLALSEMQGVFLNGRAIKVGPTSGQQ-----QHVSGNNDYN 254

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Yeast
Match: PAB1 (Poly(A) binding protein; part of the 3'-end RNA-processing complex, mediates interactions between the 5' cap structure and the 3' mRNA poly(A) tail, involved in control of poly(A) tail length, interacts with translation factor eIF-4G; stimulates, but is not required for the deadenylation activity of the Pan2p-Pan3p poly(A)-ribonuclease complex [Source:SGD;Acc:S000000967])

HSP 1 Score: 47.7506 bits (112), Expect = 6.016e-6
Identity = 30/91 (32.97%), Postives = 48/91 (52.75%), Query Frame = 2

Query:  281 IFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIK--NEAETLIFKERKLNIGHAVRKQ---HLFPRQ 538
            ++V  I S TT+E+ +  F+ +GPI    +  D  G  KG +GFV +E  E A K ++  N++E       KL +G A +K    H+  +Q
Sbjct:  221 LYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKG-FGFVNYEKHEDAVKAVEALNDSE---LNGEKLYVGRAQKKNERMHVLKKQ 307

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Yeast
Match: RIE1 (Putative RNA binding protein; localizes to stress granules induced by glucose deprivation; interacts with Rbg1p in a two-hybrid assay; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003482])

HSP 1 Score: 47.3654 bits (111), Expect = 7.704e-6
Identity = 22/50 (44.00%), Postives = 30/50 (60.00%), Query Frame = 2

Query:  272 PNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTF 421
            P  IFVGGI  + +  EL   FS YGPI  +K+I D+T      YGF+++
Sbjct:  194 PGNIFVGGIAKSLSIGELSFLFSKYGPILSMKLIYDKTKGEPNGYGFISY 243

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Nematostella
Match: EDO40536 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6X1])

HSP 1 Score: 83.5741 bits (205), Expect = 1.088e-18
Identity = 42/87 (48.28%), Postives = 61/87 (70.11%), Query Frame = 2

Query:  263 TLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIIND-RTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQ 520
             + P R+FVGG+   TTE EL+ FFS++GP+ DV+I+ D RTGL+KG +GF+TF  +E A+K+I  E   + FK R L +  A+RK+
Sbjct:   13 VIYPTRVFVGGLARGTTELELETFFSNFGPVADVRIVCDRRTGLNKG-FGFITFSLEEPAKKLI--EQNNIDFKGRSLRLRQAIRKK 96

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Nematostella
Match: EDO45185 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTC5])

HSP 1 Score: 82.0333 bits (201), Expect = 8.379e-18
Identity = 46/107 (42.99%), Postives = 61/107 (57.01%), Query Frame = 2

Query:  272 PNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHLFPRQEISGTVLYNGPVPYALQN 592
            PNRIFVGG+   TT  EL+  F SYG ++DVKI  D  G+S+G YGFVTF   + A+K+ K    T+ +K ++L IG A RK              Y+  VP AL+ 
Sbjct:    9 PNRIFVGGVAFQTTAIELRELFESYGAVRDVKIARDGEGVSRG-YGFVTFFRDDDAKKVFK--LGTVFYKGKRLVIGEAYRKLQF----------TYHSHVPRALRG 102

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Nematostella
Match: EDO43157 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZJ6])

HSP 1 Score: 77.0258 bits (188), Expect = 2.975e-16
Identity = 39/88 (44.32%), Postives = 57/88 (64.77%), Query Frame = 2

Query:  257 IGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQ 520
            +G   PN+IFVGG+   TT EEL  FF+++G + + K+I D  G+SKG YGFV+F +QE    +      TL  + +KLN+G AV+K+
Sbjct:    7 LGKRYPNKIFVGGLPPLTTAEELANFFANFGHVVESKVIFDHDGISKG-YGFVSFRSQEDVSCV--KAMGTLFLRNKKLNLGPAVKKE 91

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Nematostella
Match: EDO31802 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWW5])

HSP 1 Score: 67.781 bits (164), Expect = 2.380e-14
Identity = 31/58 (53.45%), Postives = 40/58 (68.97%), Query Frame = 2

Query:  269 IPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAE 442
            I  RIFV G    TTE EL+ FF  YG +K+ KI+ D+ G+SKG Y F+TFE+QE A+
Sbjct:    6 ISKRIFVKGFNRETTESELRAFFEEYGVVKESKIVRDKHGVSKG-YAFITFESQEVAD 62

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Nematostella
Match: EDO49349 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG33])

HSP 1 Score: 57.3806 bits (137), Expect = 1.314e-9
Identity = 29/69 (42.03%), Postives = 46/69 (66.67%), Query Frame = 2

Query:  278 RIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKE 484
            +IF+GG+  NTTEE LK +FS +G I D  +I  R G S+G +GFVT+E+ ++  +++K +   L  +E
Sbjct:    1 KIFIGGLNWNTTEEGLKDYFSQWGTIVDC-VIMKRDGRSRG-FGFVTYESSDSVNEVLKKKDHVLDDRE 67

HSP 2 Score: 46.9802 bits (110), Expect = 4.816e-6
Identity = 25/65 (38.46%), Postives = 37/65 (56.92%), Query Frame = 2

Query:  278 RIFVGGITSNTTEEELKIFFSS------YGPIKDVKIINDRTGLSK-GSYGFVTFENQETAEKII 451
            +IFVGG+ S T EE++K +F+S       G + DV +  DR    +   + FVTF+N E  EK+ 
Sbjct:   90 KIFVGGLASTTVEEDIKEYFNSLCRKNGMGEVIDVDLKRDRDNPKRIRGFAFVTFDNDEIVEKVC 154

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Medaka
Match: boll (boule homolog, RNA binding protein [Source:NCBI gene;Acc:100302724])

HSP 1 Score: 93.2041 bits (230), Expect = 8.715e-20
Identity = 59/176 (33.52%), Postives = 91/176 (51.70%), Query Frame = 2

Query:  260 GTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRK-QHLFPRQEISGTVLYNGPV------------PYALQNGLTLFQVPGQDYSVLASQSP-------QYATMMLPQPTTA-MYLPQPQYAYQ 724
            GT+IPNRIFVGG+    TE  L   FS YG + +VKI+ +R+G+SKG YGFVTFE  E    I+ ++A  + ++++K +I  AV+K Q   P   +    +++ P             PY   NG+  F  P  + +      P       Q+  + +  P+TA +Y  Q ++ YQ
Sbjct:   35 GTIIPNRIFVGGVDYKVTENHLHHIFSHYGTVTEVKIVTNRSGMSKG-YGFVTFEAPEDVVNIL-SKANRICYRDKKFSISQAVQKSQAPGPGSIVHKPFIHHDPTCDTVYLTTPAGFPYTFHNGVAYFNCPAMNQAARQWSPPQSFPQHLQWNAVQVQAPSTAVLYSQQAEFLYQ 208

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Medaka
Match: dazl (deleted in azoospermia like [Source:NCBI gene;Acc:100049418])

HSP 1 Score: 67.0106 bits (162), Expect = 4.005e-12
Identity = 40/87 (45.98%), Postives = 53/87 (60.92%), Query Frame = 2

Query:  260 GTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQ 520
            G L PN +FVGGI     E E+K FF+ YG +++VKII  R GL KG YGFV F N++    I     + +IF  RKL +G A+ K+
Sbjct:   27 GKLTPNSLFVGGIDMKVDENEIKEFFARYGSVREVKIIRYRGGLCKG-YGFVYF-NEDV--DIQSIIEQQIIFMGRKLKLGPAILKE 109

[Close]

Query:  260 GTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQ 520
            G L PN +FVGGI     E E+K FF+ YG +++VKII  R GL KG YGFV F N++    I     + +IF  RKL +G A+ K+
Sbjct:   27 GKLTPNSLFVGGIDMKVDENEIKEFFARYGSVREVKIIRYRGGLCKG-YGFVYF-NEDV--DIQSIIEQQIIFMGRKLKLGPAILKE 109

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Medaka
Match: dazl (deleted in azoospermia like [Source:NCBI gene;Acc:100049418])

HSP 1 Score: 67.0106 bits (162), Expect = 4.131e-12
Identity = 40/87 (45.98%), Postives = 53/87 (60.92%), Query Frame = 2

Query:  260 GTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQ 520
            G L PN +FVGGI     E E+K FF+ YG +++VKII  R GL KG YGFV F N++    I     + +IF  RKL +G A+ K+
Sbjct:   27 GKLTPNSLFVGGIDMKVDENEIKEFFARYGSVREVKIIRYRGGLCKG-YGFVYF-NEDV--DIQSIIEQQIIFMGRKLKLGPAILKE 109

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Medaka
Match: msi1 (musashi RNA binding protein 1 [Source:NCBI gene;Acc:101173434])

HSP 1 Score: 60.4622 bits (145), Expect = 2.934e-9
Identity = 27/68 (39.71%), Postives = 44/68 (64.71%), Query Frame = 2

Query:  251 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIK 454
            PK+ T    +IFVGG++ NTT E++K +F  +G + D  ++ D+T      +GFVTFEN++  EK+ +
Sbjct:  102 PKLVTRT-KKIFVGGLSVNTTIEDVKQYFDQFGKVDDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCE 168

HSP 2 Score: 53.5286 bits (127), Expect = 4.903e-7
Identity = 25/83 (30.12%), Postives = 42/83 (50.60%), Query Frame = 2

Query:  272 PNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQ 520
            P ++F+GG++  TT+E LK +F  YG +K+  ++ D        +GFVTF +Q   +K++      L  K     +    R Q
Sbjct:   19 PCKMFIGGLSWQTTQEGLKEYFCKYGEVKECMVMRDPVTKRSRGFGFVTFVDQAGVDKVLAQSRHELDSKTIDPKVAFPRRAQ 101

[Close]

BLAST of RRM domain-containing protein vs. Planmine SMEST
Match: SMESG000018666.1 (SMESG000018666.1)

HSP 1 Score: 720.309 bits (1858), Expect = 0.000e+0
Identity = 430/430 (100.00%), Postives = 430/430 (100.00%), Query Frame = 2

Query:  146 MSTDSQLTPKVDTLAQEFQVSLXXXXXXXXXXXXXPKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHLFPRQEISGTVLYNGPVPYALQNGLTLFQVPGQDYSVLASQSPQYATMMLPQPTTAMYLPQPQYAYQTPTAVIPSPNNGQQVTFTQNXXXXXXXXXXXXWYTLAGLTAAPXXXXXXXXXXXXXXXAQTLRWAATTGSQSPPHNNVAPAATYLLSPMASASGHEVLYIPHTGACTPXXXXXXXXXXXXXXILDSNEHNENTLVRGSLQYATFNGSDRIIPIGHAAPGSAHRLFTGPNSGLQSGTQFNPXXXXXXXXXXXXXXXXXXCGQIARMIPACSVLTASNLSRPLSRGAPGDNMQMCNNHQ 1435
            MSTDSQLTPKVDTLAQEFQVSLAAVNQATMTAAANPKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHLFPRQEISGTVLYNGPVPYALQNGLTLFQVPGQDYSVLASQSPQYATMMLPQPTTAMYLPQPQYAYQTPTAVIPSPNNGQQVTFTQNGPGSAGSAAAAPWYTLAGLTAAPQSSSQISSNNSSNSIAQTLRWAATTGSQSPPHNNVAPAATYLLSPMASASGHEVLYIPHTGACTPNSNNDFSSDNVNANILDSNEHNENTLVRGSLQYATFNGSDRIIPIGHAAPGSAHRLFTGPNSGLQSGTQFNPQAFNNSQSQLSQAALAAQCGQIARMIPACSVLTASNLSRPLSRGAPGDNMQMCNNHQ
Sbjct:    1 MSTDSQLTPKVDTLAQEFQVSLAAVNQATMTAAANPKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHLFPRQEISGTVLYNGPVPYALQNGLTLFQVPGQDYSVLASQSPQYATMMLPQPTTAMYLPQPQYAYQTPTAVIPSPNNGQQVTFTQNGPGSAGSAAAAPWYTLAGLTAAPQSSSQISSNNSSNSIAQTLRWAATTGSQSPPHNNVAPAATYLLSPMASASGHEVLYIPHTGACTPNSNNDFSSDNVNANILDSNEHNENTLVRGSLQYATFNGSDRIIPIGHAAPGSAHRLFTGPNSGLQSGTQFNPQAFNNSQSQLSQAALAAQCGQIARMIPACSVLTASNLSRPLSRGAPGDNMQMCNNHQ 430

[Close]

BLAST of RRM domain-containing protein vs. Planmine SMEST
Match: SMESG000061507.1 (SMESG000061507.1)

HSP 1 Score: 147.132 bits (370), Expect = 8.524e-39
Identity = 77/132 (58.33%), Postives = 95/132 (71.97%), Query Frame = 2

Query:  254 KIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHLFPRQEISGTVLYNG-PVPYALQNGLTLFQVPGQDYSVLASQ 646
            KI TLIPNRIFVGG   NTTEEELK FF  YG IKDVKII D+ G +KGSYGFVTF +QE AE+II  +AETL+F++RKLNIG AV+KQ L  + E+  T++ N  P+ Y      +++  P QDYS L +Q
Sbjct:   24 KISTLIPNRIFVGGFPQNTTEEELKSFFCKYGEIKDVKIIPDKAGQAKGSYGFVTFASQEVAERIITEQAETLVFRDRKLNIGRAVKKQPLTGKSELQNTLILNTLPLSYG-----SVY--PYQDYSYLFNQ 148

[Close]

BLAST of RRM domain-containing protein vs. Planmine SMEST
Match: SMESG000061507.1 (SMESG000061507.1)

HSP 1 Score: 100.523 bits (249), Expect = 3.362e-25
Identity = 49/69 (71.01%), Postives = 54/69 (78.26%), Query Frame = 2

Query:  254 KIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNE 460
            KI TLIPNRIFVGG   NTTEEELK FF  YG IKDVKII D+ G +KGSYGFVTF +QE AE+II  +
Sbjct:   24 KISTLIPNRIFVGGFPQNTTEEELKSFFCKYGEIKDVKIIPDKAGQAKGSYGFVTFASQEVAERIITEQ 92

[Close]

BLAST of RRM domain-containing protein vs. Planmine SMEST
Match: SMESG000006741.1 (SMESG000006741.1)

HSP 1 Score: 67.781 bits (164), Expect = 5.646e-12
Identity = 34/95 (35.79%), Postives = 55/95 (57.89%), Query Frame = 2

Query:  278 RIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDR-TGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHLFPRQEISGTVL 559
            +IFVGG+  +TT+E L++FF  +GPI++  +I DR +G S+G YGFVT  N E A + I N    +  ++  +N+     K  + P   ++   L
Sbjct:   35 KIFVGGLPYHTTDESLRVFFECFGPIEEAVVITDRQSGKSRG-YGFVTMVNCEDAYRAISNPNPCIDGRKANVNLAILGAKPRILPGVNLNSMAL 128

[Close]

BLAST of RRM domain-containing protein vs. Planmine SMEST
Match: SMESG000006741.1 (SMESG000006741.1)

HSP 1 Score: 63.5438 bits (153), Expect = 1.064e-11
Identity = 34/95 (35.79%), Postives = 55/95 (57.89%), Query Frame = 2

Query:  278 RIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDR-TGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHLFPRQEISGTVL 559
            +IFVGG+  +TT+E L++FF  +GPI++  +I DR +G S+G YGFVT  N E A + I N    +  ++  +N+     K  + P   ++   L
Sbjct:   35 KIFVGGLPYHTTDESLRVFFECFGPIEEAVVITDRQSGKSRG-YGFVTMVNCEDAYRAISNPNPCIDGRKANVNLAILGAKPRILPGVNLNSMAL 128

The following BLAST results are available for this feature:

BLAST of RRM domain-containing protein vs. Ensembl Human
BLAST of RRM domain-containing protein vs. Ensembl Celegans
BLAST of RRM domain-containing protein vs. Ensembl Fly
BLAST of RRM domain-containing protein vs. Ensembl Zebrafish
BLAST of RRM domain-containing protein vs. Ensembl Xenopus
BLAST of RRM domain-containing protein vs. Ensembl Mouse
BLAST of RRM domain-containing protein vs. UniProt/SwissProt
BLAST of RRM domain-containing protein vs. TrEMBL
BLAST of RRM domain-containing protein vs. Ensembl Cavefish
BLAST of RRM domain-containing protein vs. Ensembl Sea Lamprey
BLAST of RRM domain-containing protein vs. Ensembl Yeast
BLAST of RRM domain-containing protein vs. Ensembl Nematostella
BLAST of RRM domain-containing protein vs. Ensembl Medaka
BLAST of RRM domain-containing protein vs. Planmine SMEST

BLAST of RRM domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
BOLL	1.131e-33	47.70	boule homolog, RNA binding protein [Source:HGNC Sy...	[more]
BOLL	1.131e-33	47.70	boule homolog, RNA binding protein [Source:HGNC Sy...	[more]
BOLL	1.277e-33	47.70	boule homolog, RNA binding protein [Source:HGNC Sy...	[more]
BOLL	2.186e-32	48.50	boule homolog, RNA binding protein [Source:HGNC Sy...	[more]
DAZL	7.054e-21	42.98	deleted in azoospermia like [Source:HGNC Symbol;Ac...	[more]

BLAST of RRM domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
daz-1	1.313e-19	50.56	DAZ protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q2...	[more]
sup-12	2.904e-8	29.46	SUPpressor [Source:UniProtKB/TrEMBL;Acc:O45189]	[more]
sup-12	3.407e-8	29.46	SUPpressor [Source:UniProtKB/TrEMBL;Acc:O45189]	[more]
msi-1	6.244e-8	32.20	MuSashI (Fly neural) family; Neural RNA-binding pr...	[more]
H28G03.1	1.389e-7	28.95	pep chromosome:WBcel235:X:5216363:5218418:1 gene:W...	[more]

BLAST of RRM domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
bol	2.130e-26	41.95	gene:FBgn0011206 transcript:FBtr0076538	[more]
bol	2.130e-26	41.95	gene:FBgn0011206 transcript:FBtr0344979	[more]
bol	2.130e-26	41.95	gene:FBgn0011206 transcript:FBtr0076540	[more]
bol	2.477e-26	42.20	gene:FBgn0011206 transcript:FBtr0076539	[more]
bol	2.477e-26	42.20	gene:FBgn0011206 transcript:FBtr0076541	[more]

BLAST of RRM domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
dazl	3.635e-14	40.91	deleted in azoospermia-like [Source:NCBI gene;Acc:...	[more]
dazl	3.880e-14	40.91	deleted in azoospermia-like [Source:NCBI gene;Acc:...	[more]
dazl	4.643e-14	40.91	deleted in azoospermia-like [Source:NCBI gene;Acc:...	[more]
dazl	5.213e-14	40.91	deleted in azoospermia-like [Source:NCBI gene;Acc:...	[more]
dazl	5.213e-14	40.91	deleted in azoospermia-like [Source:NCBI gene;Acc:...	[more]

BLAST of RRM domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
dazl	2.934e-16	46.51	deleted in azoospermia-like [Source:NCBI gene;Acc:...	[more]
deup1	3.255e-9	37.68	deuterosome assembly protein 1 [Source:Xenbase;Acc...	[more]
msi1	1.058e-8	26.06	musashi RNA binding protein 1 [Source:NCBI gene;Ac...	[more]
psd3	1.186e-8	39.68	pleckstrin and Sec7 domain containing 3 [Source:Xe...	[more]
msi1	1.663e-8	27.34	musashi RNA binding protein 1 [Source:NCBI gene;Ac...	[more]

BLAST of RRM domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Boll	2.942e-33	45.66	boule homolog, RNA binding protein [Source:MGI Sym...	[more]
Boll	2.942e-33	45.66	boule homolog, RNA binding protein [Source:MGI Sym...	[more]
Boll	2.119e-31	61.46	boule homolog, RNA binding protein [Source:MGI Sym...	[more]
Dazl	2.676e-19	48.31	deleted in azoospermia-like [Source:MGI Symbol;Acc...	[more]
Dazl	1.871e-18	48.84	deleted in azoospermia-like [Source:MGI Symbol;Acc...	[more]

BLAST of RRM domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q8N9W6\|BOLL_HUMAN	5.433e-33	47.70	Protein boule-like OS=Homo sapiens OX=9606 GN=BOLL...	[more]
sp\|Q8WP23\|BOLL_MACFA	2.411e-32	47.13	Protein boule-like OS=Macaca fascicularis OX=9541 ...	[more]
sp\|Q924M5\|BOLL_MOUSE	2.412e-32	45.66	Protein boule-like OS=Mus musculus OX=10090 GN=Bol...	[more]
sp\|Q24207\|BOULE_DROME	2.135e-25	41.95	Protein boule OS=Drosophila melanogaster OX=7227 G...	[more]
sp\|Q92904\|DAZL_HUMAN	7.822e-20	39.24	Deleted in azoospermia-like OS=Homo sapiens OX=960...	[more]

BLAST of RRM domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A172RVQ0	2.737e-66	96.12	Boule 1 RNA-binding protein OS=Schmidtea mediterra...	[more]
A0A4S2M8S9	2.515e-61	62.15	RRM domain-containing protein OS=Opisthorchis feli...	[more]
A0A419QF17	8.505e-61	62.15	Protein boule-like OS=Clonorchis sinensis OX=79923...	[more]
A0A075AGA8	9.672e-61	62.15	RRM domain-containing protein (Fragment) OS=Opisth...	[more]
A0A4S2MEX8	1.319e-60	62.15	RRM domain-containing protein OS=Opisthorchis feli...	[more]

BLAST of RRM domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSAMXT00000005184.2	2.569e-28	35.83	pep primary_assembly:Astyanax_mexicanus-2.0:10:775...	[more]
dazl	9.738e-15	42.05	deleted in azoospermia like [Source:NCBI gene;Acc:...	[more]
msi2b	2.764e-9	31.91	RNA-binding protein Musashi homolog 2 [Source:NCBI...	[more]
msi2a	2.799e-9	31.91	RNA-binding protein Musashi homolog 2-like [Source...	[more]
msi1	2.868e-9	39.71	musashi RNA-binding protein 1 [Source:ZFIN;Acc:ZDB...	[more]

BLAST of RRM domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
BOLL	4.663e-37	45.88	boule homolog, RNA binding protein [Source:HGNC Sy...	[more]
HNRNPA0	7.686e-11	34.48	heterogeneous nuclear ribonucleoprotein A0 [Source...	[more]
HNRNPA0	2.113e-10	36.23	heterogeneous nuclear ribonucleoprotein A0 [Source...	[more]
rbm24a	4.108e-10	40.00	RNA binding motif protein 24a [Source:NCBI gene;Ac...	[more]
rbmx	5.143e-10	37.93	RNA binding motif protein X-linked [Source:NCBI ge...	[more]

BLAST of RRM domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 4


Match Name	E-value	Identity	Description
HRP1	5.111e-9	37.18	Subunit of cleavage factor I; cleavage factor I is...	[more]
NAM8	6.892e-7	34.02	RNA binding protein, component of the U1 snRNP pro...	[more]
PAB1	6.016e-6	32.97	Poly(A) binding protein; part of the 3'-end RNA-pr...	[more]
RIE1	7.704e-6	44.00	Putative RNA binding protein; localizes to stress ...	[more]

BLAST of RRM domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO40536	1.088e-18	48.28	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO45185	8.379e-18	42.99	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO43157	2.975e-16	44.32	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO31802	2.380e-14	53.45	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49349	1.314e-9	42.03	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of RRM domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
boll	8.715e-20	33.52	boule homolog, RNA binding protein [Source:NCBI ge...	[more]
dazl	4.005e-12	45.98	deleted in azoospermia like [Source:NCBI gene;Acc:...	[more]
dazl	4.005e-12	45.98	deleted in azoospermia like [Source:NCBI gene;Acc:...	[more]
dazl	4.131e-12	45.98	deleted in azoospermia like [Source:NCBI gene;Acc:...	[more]
msi1	2.934e-9	39.71	musashi RNA binding protein 1 [Source:NCBI gene;Ac...	[more]

BLAST of RRM domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000018666.1	0.000e+0	100.00	SMESG000018666.1	[more]
SMESG000061507.1	8.524e-39	58.33	SMESG000061507.1	[more]
SMESG000061507.1	3.362e-25	71.01	SMESG000061507.1	[more]
SMESG000006741.1	5.646e-12	35.79	SMESG000006741.1	[more]
SMESG000006741.1	1.064e-11	35.79	SMESG000006741.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30020626 ID=SMED30020626|Name=RRM domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2287bp
ATCAAAATCAGTTTATAAATTTAAATTTTATTTGAATTTTAGAGTATTAC
TTTTATTAAAATATCTTAAGTTATATTAATTTAACAAAGAATTTATAGTA
ACCAATCAATGCTAAGGATTGAAAATTAGTGTGTATGCAAACAAAATGTC
AACTGATAGTCAACTTACGCCTAAAGTAGATACACTAGCTCAAGAATTTC
AAGTTTCACTTGCTGCTGTTAATCAAGCAACGATGACTGCTGCTGCAAAC
CCTAAAATCGGTACTCTGATACCAAATCGAATATTTGTTGGTGGAATCAC
GTCAAATACGACAGAAGAAGAATTGAAAATATTTTTTTCAAGTTACGGTC
CAATTAAGGATGTTAAAATAATAAATGATCGTACTGGATTATCCAAAGGG
AGTTATGGGTTTGTTACATTTGAAAATCAAGAAACTGCTGAAAAAATAAT
CAAAAATGAAGCAGAAACACTGATATTTAAGGAACGGAAATTAAACATAG
GACACGCTGTTAGAAAACAGCATTTATTTCCTCGCCAGGAAATTTCTGGA
ACAGTTTTATATAATGGACCCGTGCCTTATGCTTTACAAAATGGTTTAAC
ATTGTTCCAAGTTCCTGGACAAGACTATTCAGTTTTAGCGTCACAATCTC
CTCAATACGCAACTATGATGTTACCTCAACCGACTACGGCTATGTATTTA
CCGCAACCACAATATGCTTATCAAACGCCTACTGCTGTGATTCCTTCCCC
TAACAACGGACAACAAGTAACATTTACTCAAAACGGTCCTGGATCAGCAG
GATCAGCAGCTGCTGCACCATGGTACACTTTAGCTGGATTAACGGCAGCA
CCACAATCATCTTCACAAATTTCAAGCAACAATAGTTCAAATTCAATTGC
TCAAACTTTAAGATGGGCTGCTACAACTGGATCACAAAGTCCTCCACATA
ATAATGTAGCGCCTGCAGCAACTTATTTATTGAGTCCAATGGCTAGTGCT
TCTGGTCACGAAGTTTTGTATATTCCTCATACTGGTGCTTGTACACCAAA
TTCCAACAATGATTTTTCCTCTGACAATGTAAATGCAAACATTTTGGATT
CGAATGAACATAATGAAAATACTTTGGTGCGTGGAAGTTTACAATACGCA
ACTTTTAATGGTTCTGACCGTATAATTCCCATTGGACATGCAGCACCAGG
TTCTGCTCATCGACTTTTTACAGGTCCCAATTCTGGATTACAATCTGGAA
CTCAATTTAATCCTCAGGCATTTAACAATTCTCAAAGTCAATTAAGTCAA
GCCGCATTAGCAGCACAGTGTGGACAAATTGCAAGAATGATTCCTGCATG
TTCAGTGTTAACTGCATCTAATTTGTCACGACCTCTTAGCCGAGGTGCGC
CTGGCGATAATATGCAAATGTGTAATAATCATCAATAAGACAACTACCTC
CCTTTAAAAAAATACTTAAGTTGTATTTATATTATTGTTTTCTTTATTTT
TAGTATAGGCCTCAGTTTAAAATTATGATTATTTTTATCTGTAATACCGA
TAATTTGAATTTTTATGTGTAACTTATCTGAAATTTGATTTAAATGATCA
GTCATTCATTTCTTGTGTAACACATGAGTAACAAATGTTTTGTTTAAAGC
ATGACAATGTTATTTTGAAATTTGAGTATTTCATGTTGTAGTTTGTCCAT
CTAGTCTCCTAGAATAGTTTGTGAGTTCGTTGTTGAGATATTGTTGAAAT
CAATTAACATTTAACTTATTAATCTTAACTAAAATATAATTGTTATTAAA
TTTTAAATGTGACATTTTAAAATCGCAGTATAATTTACGTTATGAAGAAT
CTATATGTTTTACCTAGATAATGTGCACTTTTCGAGTTTTTAACATGCTT
TATGGCAACTGCTGGTGGTATTTACAGCATTCCTTTTTGTAATGGTACGC
ATGCTACTTTTTGGGACTGATGATGAATGACTGACAGTTTGTTGTAATAA
ATGGGTTTATTGTTAAATTTAGTTCGGACTTTGCTATTCTGATATAAACA
TGATGAGAAATGCTATTTGTTGTATCTCTTTCGATAATTAATGTGTTTCA
TTTTCAAATTAATTTTATATTTTACTAATTTATTTCATGTTACCTTTATA
ACACTGAATATTATATATCAAAAGTATATATTATATAGATTGGTTTTTAT
GATGGCTTAAGATAATGAAGTTTTTGTTAGTTTGTTAATTTAGATGTTAT
TCATATATAGATGTTTTGTTTCATTAAATATTATTAA

protein sequence of SMED30020626-orf-1

>SMED30020626-orf-1 ID=SMED30020626-orf-1|Name=SMED30020626-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=431bp
MSTDSQLTPKVDTLAQEFQVSLAAVNQATMTAAANPKIGTLIPNRIFVGG
ITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEK
IIKNEAETLIFKERKLNIGHAVRKQHLFPRQEISGTVLYNGPVPYALQNG
LTLFQVPGQDYSVLASQSPQYATMMLPQPTTAMYLPQPQYAYQTPTAVIP
SPNNGQQVTFTQNGPGSAGSAAAAPWYTLAGLTAAPQSSSQISSNNSSNS
IAQTLRWAATTGSQSPPHNNVAPAATYLLSPMASASGHEVLYIPHTGACT
PNSNNDFSSDNVNANILDSNEHNENTLVRGSLQYATFNGSDRIIPIGHAA
PGSAHRLFTGPNSGLQSGTQFNPQAFNNSQSQLSQAALAAQCGQIARMIP
ACSVLTASNLSRPLSRGAPGDNMQMCNNHQ*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0003723	RNA binding
GO:0003729	mRNA binding
GO:0003676	nucleic acid binding
GO:0000166	nucleotide binding

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0016021	integral component of membrane

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000070	intestinal phagocyte
PLANA:0000204	ovary
PLANA:0000208	testis
PLANA:0000219	spermatogonial stem cell
PLANA:0000220	spermatogonium
PLANA:0000221	spermatocyte
PLANA:0000222	spermatid
PLANA:0000422	tail stripe
PLANA:0000429	neoblast
PLANA:0002089	reproductive organ
PLANA:0002109	X1 cell
PLANA:0002111	X2 cell
PLANA:0002142	parenchyma
PLANA:0003304	testis primordium

Vocabulary: **INTERPRO**
Term	Definition
IPR037366	BOULE/DAZ
IPR034988	DAZ_BOULE_RRM
IPR035979	RBD_domain_sf
IPR000504	RRM_dom
IPR012677	Nucleotide-bd_a/b_plait_sf

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR000504	RNA recognition motif domain	SMART	SM00360	rrm1_1	coord: 45..119 e-value: 1.5E-19 score: 81.0
IPR000504	RNA recognition motif domain	PFAM	PF00076	RRM_1	coord: 46..107 e-value: 1.0E-17 score: 63.7
IPR000504	RNA recognition motif domain	PROSITE	PS50102	RRM	coord: 44..123 score: 16.261
IPR012677	Nucleotide-binding alpha-beta plait domain superfamily	GENE3D	G3DSA:3.30.70.330		coord: 38..132 e-value: 4.7E-24 score: 86.4
IPR037366	BOULE/DAZ family	PANTHER	PTHR11176	BOULE-RELATED	coord: 28..324
None	No IPR available	PANTHER	PTHR11176:SF14	PROTEIN BOULE	coord: 28..324
IPR034988	DAZ/BOULE, RNA recognition motif	CDD	cd12412	RRM_DAZL_BOULE	coord: 42..124 e-value: 2.85079E-39 score: 133.938
IPR035979	RNA-binding domain superfamily	SUPERFAMILY	SSF54928	RNA-binding domain, RBD	coord: 43..137