G_PROTEIN_RECEP_F1_2 domain-containing protein

Overview
NameG_PROTEIN_RECEP_F1_2 domain-containing protein
Smed IDSMED30020621
Length (bp)1325
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of G_PROTEIN_RECEP_F1_2 domain-containing protein (SMED30020621) t-SNE clustered cells

Violin plots show distribution of expression levels for G_PROTEIN_RECEP_F1_2 domain-containing protein (SMED30020621) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of G_PROTEIN_RECEP_F1_2 domain-containing protein (SMED30020621) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for G_PROTEIN_RECEP_F1_2 domain-containing protein (SMED30020621) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30020621

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30020621h1SMcG0014595 SmedASXL_013185SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
head regionSMED30020621h1SMcG0014595 dd_Smed_v6_18754_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
dorsal-ventral muscle cellSMED30020621h1SMcG0014595 dd_Smed_v4_18754_0_1dd_Smed_v4PMID:30471994
Scimone et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: SPR (gene:FBgn0029768 transcript:FBtr0344824)

HSP 1 Score: 59.3066 bits (142), Expect = 3.568e-9
Identity = 92/362 (25.41%), Postives = 154/362 (42.54%), Query Frame = 1 
Query:  103 PILLIVGSFGNIMVPIVLYRHSRVISTYVYLISLAIADQTVLIFGTTPKWLQHTFGVNIEN----SSNATCKLFAFVGMAFSQ-IAVWLIXXXXXXXXXXXSLPFKAPQHITVTRAVICVSVVTIFFLSINCPLFFTVVLLDSSEDSPENNSYSNSVCDMR-----RDFQFPITMIWS---WFDGLFYSYLPCLXXXXXXXXXXHFLRTAHKRRLLMQCSTVNINSHNTLVNHSRQTSCNYKPANQSSQQLFMLILVSWVFVLTVIPISI---FKIVNNIVKKHYPFYLENQEVMSEFLLINTVVETFMTTNHSINFFLYCIAGKKFR----TYFLLLLSCSKFSNNSNASIVGASVLLNSN 1128
            P LLI+    N ++ +VL + S    T   L+ +AI D   +IF     W  +TFG + +     S      +F  +  A    I+VWL + + V+R I V     A    T+ R   C + + +       P FF    +       E N     VC +       D+   + + ++    F  LF   LPC+I++  NI++   +R A +RR L             L   +R+  C  K   +++    MLI+V  VF+L  IPI++     IV++++ +   + L N  +M        +   F+  ++ INF +YC   ++FR      FL  L   K S+   + + GA    N+N
Sbjct:   97 PFLLIITIISNSLIVLVLSKKSMATPTNFVLMGMAICDMLTVIFPAPGLWYMYTFGNHYKPLHPVSMCLAYSIFNEIMPAMCHTISVWLTLALAVQRYIYVCHAPMARTWCTMPRVRRCTAYIALLAFLHQLPRFFDRTYMPLVI---EWNGSPTEVCHLETSMWVHDY-IGVDLYYTSYYLFRVLFVHLLPCIILVTLNILLFAAMRQAQERRKL-------------LFRENRKKEC--KKLRETNCTTLMLIVVVSVFLLAEIPIAVVTAMHIVSSLIIEFLDYGLANICIM--------LTNFFLVFSYPINFGIYCGMSRQFRETFKEIFLGRLMAKKDSSTKYSIVNGARTCTNTN 431
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: SPR (gene:FBgn0029768 transcript:FBtr0339781)

HSP 1 Score: 59.3066 bits (142), Expect = 3.568e-9
Identity = 92/362 (25.41%), Postives = 154/362 (42.54%), Query Frame = 1 
Query:  103 PILLIVGSFGNIMVPIVLYRHSRVISTYVYLISLAIADQTVLIFGTTPKWLQHTFGVNIEN----SSNATCKLFAFVGMAFSQ-IAVWLIXXXXXXXXXXXSLPFKAPQHITVTRAVICVSVVTIFFLSINCPLFFTVVLLDSSEDSPENNSYSNSVCDMR-----RDFQFPITMIWS---WFDGLFYSYLPCLXXXXXXXXXXHFLRTAHKRRLLMQCSTVNINSHNTLVNHSRQTSCNYKPANQSSQQLFMLILVSWVFVLTVIPISI---FKIVNNIVKKHYPFYLENQEVMSEFLLINTVVETFMTTNHSINFFLYCIAGKKFR----TYFLLLLSCSKFSNNSNASIVGASVLLNSN 1128
            P LLI+    N ++ +VL + S    T   L+ +AI D   +IF     W  +TFG + +     S      +F  +  A    I+VWL + + V+R I V     A    T+ R   C + + +       P FF    +       E N     VC +       D+   + + ++    F  LF   LPC+I++  NI++   +R A +RR L             L   +R+  C  K   +++    MLI+V  VF+L  IPI++     IV++++ +   + L N  +M        +   F+  ++ INF +YC   ++FR      FL  L   K S+   + + GA    N+N
Sbjct:   97 PFLLIITIISNSLIVLVLSKKSMATPTNFVLMGMAICDMLTVIFPAPGLWYMYTFGNHYKPLHPVSMCLAYSIFNEIMPAMCHTISVWLTLALAVQRYIYVCHAPMARTWCTMPRVRRCTAYIALLAFLHQLPRFFDRTYMPLVI---EWNGSPTEVCHLETSMWVHDY-IGVDLYYTSYYLFRVLFVHLLPCIILVTLNILLFAAMRQAQERRKL-------------LFRENRKKEC--KKLRETNCTTLMLIVVVSVFLLAEIPIAVVTAMHIVSSLIIEFLDYGLANICIM--------LTNFFLVFSYPINFGIYCGMSRQFRETFKEIFLGRLMAKKDSSTKYSIVNGARTCTNTN 431
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: SPR (gene:FBgn0029768 transcript:FBtr0070778)

HSP 1 Score: 59.3066 bits (142), Expect = 3.568e-9
Identity = 92/362 (25.41%), Postives = 154/362 (42.54%), Query Frame = 1 
Query:  103 PILLIVGSFGNIMVPIVLYRHSRVISTYVYLISLAIADQTVLIFGTTPKWLQHTFGVNIEN----SSNATCKLFAFVGMAFSQ-IAVWLIXXXXXXXXXXXSLPFKAPQHITVTRAVICVSVVTIFFLSINCPLFFTVVLLDSSEDSPENNSYSNSVCDMR-----RDFQFPITMIWS---WFDGLFYSYLPCLXXXXXXXXXXHFLRTAHKRRLLMQCSTVNINSHNTLVNHSRQTSCNYKPANQSSQQLFMLILVSWVFVLTVIPISI---FKIVNNIVKKHYPFYLENQEVMSEFLLINTVVETFMTTNHSINFFLYCIAGKKFR----TYFLLLLSCSKFSNNSNASIVGASVLLNSN 1128
            P LLI+    N ++ +VL + S    T   L+ +AI D   +IF     W  +TFG + +     S      +F  +  A    I+VWL + + V+R I V     A    T+ R   C + + +       P FF    +       E N     VC +       D+   + + ++    F  LF   LPC+I++  NI++   +R A +RR L             L   +R+  C  K   +++    MLI+V  VF+L  IPI++     IV++++ +   + L N  +M        +   F+  ++ INF +YC   ++FR      FL  L   K S+   + + GA    N+N
Sbjct:   97 PFLLIITIISNSLIVLVLSKKSMATPTNFVLMGMAICDMLTVIFPAPGLWYMYTFGNHYKPLHPVSMCLAYSIFNEIMPAMCHTISVWLTLALAVQRYIYVCHAPMARTWCTMPRVRRCTAYIALLAFLHQLPRFFDRTYMPLVI---EWNGSPTEVCHLETSMWVHDY-IGVDLYYTSYYLFRVLFVHLLPCIILVTLNILLFAAMRQAQERRKL-------------LFRENRKKEC--KKLRETNCTTLMLIVVVSVFLLAEIPIAVVTAMHIVSSLIIEFLDYGLANICIM--------LTNFFLVFSYPINFGIYCGMSRQFRETFKEIFLGRLMAKKDSSTKYSIVNGARTCTNTN 431
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: CNMaR (gene:FBgn0053696 transcript:FBtr0091684)

HSP 1 Score: 52.7582 bits (125), Expect = 4.112e-7
Identity = 51/177 (28.81%), Postives = 86/177 (48.59%), Query Frame = 1 
Query:   82 YIYVIFPPILLIVGSFGNIMVPIVLYRHS-RVISTYVYLISLAIADQTVLIFGTTPKWLQHTFGVNIENSSNATCKLFAFVGMAFSQIAVWLIXXXXXXXXXXXSLPFKAPQHITVTRAVICVSVVTIFFLSINCPLFFTVVLLDSSEDSPENNSYSNSVCDMRRDFQFPITMIWSW 609
            +++  + P+L   GS GNI+   V +R   R +S+  YL +LA++D T  + G   +WL     V+I N  N  C+ F F     S  +VW +V  TVER I V  P K     TV RA I +  +T+    + C      +++      P+ N+   ++CD+  +++  + +   W
Sbjct:   60 FVHQYYIPVLCCTGSIGNILSVFVFFRTKLRKLSSSFYLAALAVSD-TCFLAGLFAQWLNF-LNVDIYN-QNYFCQFFTFFSYLASFCSVWFVVAFTVERFIAVIYPLKRQTMCTVRRAKIVLFCLTL----VGCLHCLPYIVIAKPVFMPKLNT---TICDLNSEYKEQLALFNYW 226
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A2T7NJU4 (G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_19599 PE=3 SV=1)

HSP 1 Score: 161.77 bits (408), Expect = 1.944e-41
Identity = 124/367 (33.79%), Postives = 192/367 (52.32%), Query Frame = 1 
Query:   55 NFSTYRQMKYIYVIFPPILLIVGSFGNIMVPIVLYRHS-RVISTYVYLISLAIADQTVLIFGTTPKWLQHTFGVNIENSSNATCKLFAFVGMAFSQIAVWLIXXXXXXXXXXXSLPFKAPQHITVTRAVICVSVVTIFFLSINCPLFFTVVLLDSSEDSPENNSYSNSVCDMRRDFQFPITMIWSWFDGLFYSYLPCLXXXXXXXXXXHFLRTAHKRRLLMQ------CSTVNINSHNTLVNHSRQTSCNYKPANQSSQQL-FMLILVSWVFVLTVIPISIFKIVNNIVKKHYPFYLENQEV--MSEFLLINTVVETFMTTNHSINFFLYCIAGKKFRTYFLLLLSCSKFSNNSNASIVGASVLLNS 1125
            ++  YR +KY+ V  PP+L+I+G+FGN++  IVL R +   +S+Y+YL SLAIAD  VL  G    WL    GVN +++S   CK+  F+G   S ++VWLI+ VTVER IVV  P +A       RA + +  +      +N   F+TV L++ + DS      + ++C+    +   +  +W W D   YS+LP +II+  N++II  +  A   RL +Q              H T    +  + C    A+    +L  ML+ VS+ F+LT +P++I  IV    ++      +N  +  +++  L  T+ E  M  NHSINFFLYC  G+KFR     L+ C K ++ S  S+      LNS
Sbjct:   12 DYPEYRLLKYLLVYIPPVLIILGTFGNVVSFIVLRRRAMSKVSSYLYLASLAIADSLVLYIGLLRLWLDELTGVNFQDNSEWLCKVTMFLGYLASDLSVWLIIAVTVERYIVVCFPLRAFTMCNTNRAKLVIIFIVFLICCMNMHFFWTVGLVERATDSD-----NITICEAAPAYNHLVDDVWPWVDACVYSFLPFVIILVCNVLIITEVVEARAHRLNLQNMPDYHYHQQKQLQHRTSTTGTAISGCRRSCASGEGTKLTVMLLTVSFTFLLTTLPMNISLIVTAFWEQ------QNHGIRQIAQLKLAKTIAELLMYVNHSINFFLYCATGQKFRQQIAHLMCCRKETSTSWNSMHTEHTPLNS 367
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A1S3J0N5 (FMRFamide receptor-like OS=Lingula unguis OX=7574 GN=LOC106168745 PE=3 SV=1)

HSP 1 Score: 155.992 bits (393), Expect = 3.720e-39
Identity = 138/391 (35.29%), Postives = 205/391 (52.43%), Query Frame = 1 
Query:   79 KYIYVIFPPILLIVGSFGNIMVPIVLYRHSRV-ISTYVYLISLAIADQTVLIFGTTPKWLQHTFGVNIENSSNATCKLFAFVGMAFSQIAVWLIXXXXXXXXXXXSLPFKAPQHITVTRAVICVSVVTIFFLSINCPLFFTVVLLDSSEDSPENNSYSNSVCDMRRDFQFPITMIWSWFDGLFYSYLPCLXXXXXXXXXXHFLRTAHKRRLLMQCSTVNINSHNTLVNHSRQTSCNYKPANQSSQQL-FMLILVSWVFVLTVIPISIFKIVNNIVKKHYPFYLENQ-EVMSEFLLINTVVETFMTTNHSINFFLYCIAGKKFRTYFLLLLSCSK----FSN-----NSNASIVGASVLLNSNCSRKFVK-----SPMELPNRTKKILSNDQ 1200
            K + +  P IL+++G+FGNI   IVL + + + +STY YL +L++AD  VL FG    W+    G+++++ ++ +CKL A +G + S  +VWLI+ VTVER IVV  P KA +   + RA I +  + +  L+IN   F+TV L  S  D P+        CD    ++  IT IW W D + YS+LP   I+  N III  +  A + R  +Q         NT +   R+T+       +SS +L  ML+ VS+ FVLT +PI++F     I K  +  Y E   +      +I+T  +  M  NHSINFFLYC  G+KFR     +L C +    FSN     N   S+V +S    +NC  K V      S ME+ +R  +  +N Q
Sbjct:   60 KSLLLYIPIILVVIGTFGNIFSFIVLRQKAMMTLSTYFYLAALSLADTVVLYFGLFRLWIWQLTGMDVQHYADWSCKLVAVIGYSASDFSVWLIIAVTVERYIVVCHPLKASELCNIPRAKIVMGALFMLLLTINLHFFWTVELSTSESDIPK--------CDGGPQYKHLITEIWPWVDAVIYSFLPFGTILIMNCIIIRQVIHARRSREELQ---------NTSLKERRRTT------QESSIKLTIMLLTVSFTFVLTTLPINVFM----IAKAFFQSYSEQDIDEKGRREVIHTSAKLLMYLNHSINFFLYCATGQKFRHQVKRIL-CRRSKTFFSNFTQIRNGRESMVWSSTKY-TNCPSKIVADTTDMSEMEM-HRLHQTRTNQQ 420
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A210QEM0 (Thyrotropin-releasing hormone receptor OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT13496 PE=3 SV=1)

HSP 1 Score: 152.14 bits (383), Expect = 1.154e-37
Identity = 110/361 (30.47%), Postives = 179/361 (49.58%), Query Frame = 1 
Query:   49 FNNFSTYRQMKYIYVIFPPILLIVGSFGNIMVPIVLYRHSRVISTYVYLISLAIADQTVLIFGTTPKWLQHTFGVNIENSSNATCKLFAFVGMAFSQIAVWLIXXXXXXXXXXXSLPFKAPQHITVTRAVICVSVVTIFFLSINCPLFFTVVLLDSSEDSPENNSYSNSVCDMRRDFQFPITMIWSWFDGLFYSYLPCLXXXXXXXXXXHFLRTAHKRRLLMQCSTVNINSHNTLVNHSRQTSCNYKP--ANQSSQQL-FMLILVSWVFVLTVIPISIFKIVNNIVKKHYPFYLENQEVMSEFLLINTVVETFMTTNHSINFFLYCIAGKKFRTY-FLLLLSC-SKFSNNSNASIVGASVL 1116
               F+++R  K++ +  PP+++++G+ GNI+   V   +S  +STY YL +LAI D  V+  G    W+      +I++ +N TCK+ AF+G   S  +VWLIV VT+ER I V  P +A     + +A   V V  +    +N    +T+ LL    ++ E       +CD   +F   +  +W W D   YS++P +            + +    R++ + S       + L        CN +     + S++L  ML+LVS+ F+LT +P++I  I+         +  +NQ+  ++F L  TV E  M  NH+INFFLYCI G+KFR   FLL   C S+   N + +  G   L
Sbjct:   62 LEEFASFRVHKWLLLYVPPVMILIGTIGNILSFTVFRINSGKVSTYTYLSALAIMDLLVIYIGLLRLWVAQLSNFDIKDQTNWTCKVVAFLGYVCSDSSVWLIVAVTLERYIAVCYPLQAANLCRIRKARFIVFVPILALCVVNSHFLWTLELLHVVNNTTE----PMYICDAGHNFSALVNDVWPWVDAGIYSFVPFV------------ILSILNGRIIQKVSVAKNERKHLLTKDRNGKGCNVRKHSTGEVSRKLTMMLLLVSFTFLLTTLPMNIILIMTK------SWNEQNQQQRADFFLAKTVTELLMYLNHTINFFLYCITGRKFRRQIFLLFCRCFSQPDKNGDMARTGLRTL 400
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A210QEF5 (Thyrotropin-releasing hormone receptor OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT13495 PE=4 SV=1)

HSP 1 Score: 151.369 bits (381), Expect = 1.940e-37
Identity = 111/361 (30.75%), Postives = 175/361 (48.48%), Query Frame = 1 
Query:   49 FNNFSTYRQMKYIYVIFPPILLIVGSFGNIMVPIVLYRHSRVISTYVYLISLAIADQTVLIFGTTPKWLQHTFGVNIENSSNATCKLFAFVGMAFSQIAVWLIXXXXXXXXXXXSLPFKAPQHITVTRAVICVSVVTIFFLSINCPLFFTVVLLDSSEDSPENNSYSNSVCDMRRDFQFPITMIWSWFDGLFYSYLPCLXXXXXXXXXXHFLRTAHKRRLLMQCSTVNINSHNTLVNHSRQTSCNYKP--ANQSSQQL-FMLILVSWVFVLTVIPISIFKIVNNIVKKHYPFYLENQEVMSEFLLINTVVETFMTTNHSINFFLYCIAGKKFRTY-FLLLLSC-SKFSNNSNASIVGASVL 1116
               F+ +R  K++ +  PP+++++G+ GN++        S  +STY YL +LAI D  V+  G    W+      +I++ +N TCK+ AF+G   S  +VWLIV VT+ER I    P +A     + +A   V V  +    +N    +TV LL    ++ E       +CD   +F   +  +W W D   YS++P +            L   + R +   C   N   H  L        CN +     + S++L  ML+LVS+ F+LT +P++I  I+     +      +NQ+  ++F L  TV E  M  NH+INFFLYCI G+KFR   FLL   C S+   N + ++ G   L
Sbjct:   51 LEEFAGFRVHKWLLLYVPPVMILIGTIGNLLSFTAFRNSSGKVSTYPYLSALAIMDLLVIYIGLLRLWVAQLSNFDIKDQTNWTCKVVAFLGYVCSDSSVWLIVAVTLERYIAGCYPLQAANLCRIRKARFIVFVPILALCVVNSHFLWTVELLHVVNNTTE----PVYICDAGHNFSALVNDVWPWVDAGIYSFVPFV-----------ILSILNGRIIQKVCVAKNERKH-LLTKDRNGKGCNVRKHSTGEVSRKLTMMLLLVSFTFLLTTLPMNIILIMTKSWNE------QNQQQRADFFLAKTVTELLMYLNHTINFFLYCITGRKFRRQIFLLFCRCFSQPDQNGDMAMTGLRTL 389
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A210PZW9 (Thyrotropin-releasing hormone receptor OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT13718 PE=3 SV=1)

HSP 1 Score: 150.599 bits (379), Expect = 3.803e-37
Identity = 115/357 (32.21%), Postives = 186/357 (52.10%), Query Frame = 1 
Query:   43 EAFNNFSTYRQMKYIYVIFPPILLIVGSFGNIMVPIVLYRHSRV--ISTYVYLISLAIADQTVLIFGTTPKWLQHTFGVNIENSSNATCKLFAFVGMAFSQIAVWLIXXXXXXXXXXXSLPFKAPQHITVTRAVICVSVVTIFFLSINCPLFFTVVLLDSSEDSPENNSYSNSV---CDMRRDFQFPITMIWSWFDGLFYSYLPCLXXXXX-XXXXXHFLRTAHKRRLLMQCSTVNINSHNTLVNHSRQTSCNYKPANQSSQQLFMLILVSWVFVLTVIPISIFKIVNNIVKKHYPFYLENQEVMSEFLLINTVVETFMTTNHSINFFLYCIAGKKFRTYFLLLLSCSKFSNNSNAS 1095
            E    +  YR    + +  PP+LL +G+ GN++  ++L RH  +  +ST  +L +L+IAD  VL+ G   KWL     V+++  S   CKL A +G + SQ +VWLIV VT+ER IVV  P +A     + RA   V ++ + FL+IN  L +TV   D +E+      Y+N +   C+     +  + +IW W D LFYS+ P LII+    +II   ++  + R +L   S +   S                  + +++   ML+ +S+ F+LT +P++I  IV  + +  +     +  ++++ LL+ T+ E  M  NHS+NFFLYC  G+KFR     ++     SN SN S
Sbjct:   60 EDLIQYKEYRIHTTMAIYMPPVLLFLGTVGNVLSFLIL-RHKTMTRMSTNTFLAALSIADSFVLLNGLFLKWLGEITHVDLQTESRLLCKLIAVLGYSTSQYSVWLIVAVTIERYIVVCHPLRASYFCNIPRARKVVCLLALLFLTINIHLLWTV---DLNEE-----IYNNKIVYKCEGALSHKLLVDVIWPWIDALFYSFSPTLIIVMLNIMIIRQVIKATYGRDVLQNGSLMKAESRRC-------------TKDSNTKLTVMLLTISFTFLLTTLPMNIVMIVTRVWQDDFK---NDAAILAKCLLVRTIAELLMYLNHSMNFFLYCATGQKFRNIVYRMVCQRSGSNTSNVS 391
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Match: drd2a (D(2)-like dopamine receptor [Source:NCBI gene;Acc:103036974])

HSP 1 Score: 48.9062 bits (115), Expect = 6.477e-6
Identity = 45/169 (26.63%), Postives = 86/169 (50.89%), Query Frame = 1 
Query:   31 ENELEAFNNFSTYRQMKY-IYVIFPPILLIVGSFGNIMVPIVLYRHSRVISTYVYLI-SLAIADQTVLIFGTTPKWLQHTFGVNIENSSNATCKLFAFVGMAFSQIAVWLIXXXXXXXXXXXSLP-FKAPQHITVTRAVICVSVVTIFFLSINCPLFFTVVLLDSSEDS 528
            EN L+ FN+    R+ +Y  Y +   +L+ V  FGN++V + + R   + +T  YLI SLA+AD  +L+      W+ +   V     S   C +F  + +     ++  +  ++++R   V++P     ++ +  R  + +SVV I   +I+CPL F +   +S +D+
Sbjct:    5 ENGLDGFNSTDGGRKHQYNYYAMLLTLLIFVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVAD--LLVATLVMPWVVYLEVVGEWRFSTIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSRRRVTVMISVVWILSFAISCPLLFGLNNTESRDDA 171
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Match: drd2a (D(2)-like dopamine receptor [Source:NCBI gene;Acc:103036974])

HSP 1 Score: 48.9062 bits (115), Expect = 6.750e-6
Identity = 45/169 (26.63%), Postives = 86/169 (50.89%), Query Frame = 1 
Query:   31 ENELEAFNNFSTYRQMKY-IYVIFPPILLIVGSFGNIMVPIVLYRHSRVISTYVYLI-SLAIADQTVLIFGTTPKWLQHTFGVNIENSSNATCKLFAFVGMAFSQIAVWLIXXXXXXXXXXXSLP-FKAPQHITVTRAVICVSVVTIFFLSINCPLFFTVVLLDSSEDS 528
            EN L+ FN+    R+ +Y  Y +   +L+ V  FGN++V + + R   + +T  YLI SLA+AD  +L+      W+ +   V     S   C +F  + +     ++  +  ++++R   V++P     ++ +  R  + +SVV I   +I+CPL F +   +S +D+
Sbjct:   15 ENGLDGFNSTDGGRKHQYNYYAMLLTLLIFVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVAD--LLVATLVMPWVVYLEVVGEWRFSTIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSRRRVTVMISVVWILSFAISCPLLFGLNNTESRDDA 181
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
Match: trhr2 (TRHR2 protein [Source:NCBI gene;Acc:100533510])

HSP 1 Score: 58.5362 bits (140), Expect = 4.970e-9
Identity = 95/335 (28.36%), Postives = 136/335 (40.60%), Query Frame = 1 
Query:  118 VGSFGNIMVPIVLY--RHSRVISTYVYLISLAIADQTVLIFGTTPKWLQHTFGVNIENSSNATCKLFAFVGMAFSQIAVWLIXXXXXXXXXXXSLPFKAPQHITVTRAVICVSVVTIFFLSINCPLFFTVVLLDSSEDSPENNSYSNSVCDMRRDFQFPITMIWSWFDGLFYSYLPCLXXXXXXXXXXHFLRTAHKRRLLMQCSTVNINSHNTLVNHSRQTSCNYKPANQS---------SQQLFMLILVSWVFVLTVIPISIFKIVNNIVKKHYPFYLENQEVMSEFLLINTVVETFMTTNHSINFFLYCIAGKKFRTYFLLLLSCSKFSNNSN 1089
            VG  GN+MV +V++  RH R   T  YL+SLAIAD TVL+    P       G  I     A C    ++      ++   I   TVER I +  P KA    TV+RA   ++ V I F  + C L+  +V +    D      Y      ++R+   PI +I    D   +  +P L+ I    +I   L   +   L  Q  T    S  TL    R TS   +P  Q           Q   ML +V  +F L  +P     ++N+ V   Y        + + FLL      T +  N +IN  +Y    +KFR  F  L SC +   N  
Sbjct:   35 VGIIGNVMVVLVVFTTRHMRT-PTNCYLVSLAIADLTVLVAAGLPNVSDSLTGTWIFG--QAGCLGITYLQYLGINVSSCSITAFTVERYIAICHPMKAQTVCTVSRAKRIIAGVWI-FTCVYCMLWLFLVDIQVGPDGHVQCGYR-----VKRELYLPIYLI----DFAIFYVIPLLLAIVLYALIARIL---YLSPLPHQPDT----SATTLRRSCRDTSEAARPGRQGRPKSALSSRKQVTKMLAVVVILFALLWMPYRTLVLINSFVSTPY--------LNAWFLLF---CRTCIYANSAINPVIYNAMSQKFRLAFRGLYSCQRLEGNQR 338
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
Match: trhr2 (TRHR2 protein [Source:NCBI gene;Acc:100533510])

HSP 1 Score: 56.9954 bits (136), Expect = 2.076e-8
Identity = 95/333 (28.53%), Postives = 136/333 (40.84%), Query Frame = 1 
Query:  118 VGSFGNIMVPIVLY--RHSRVISTYVYLISLAIADQTVLIFGTTPKWLQHTFGVNIENSSNATCKLFAFVGMAFSQIAVWLIXXXXXXXXXXXSLPFKAPQHITVTRAVICVSVVTIFFLSINCPLFFTVVLLDSSEDSPENNSYSNSVCDMRRDFQFPITMIWSWFDGLFYSYLPCLXXXXXXXXXXHFLRTAHKRRLLMQCSTVNINSHNTLVNHSRQTSCNYKPANQS---------SQQLFMLILVSWVFVLTVIPISIFKIVNNIVKKHYPFYLENQEVMSEFLLINTVVETFMTTNHSINFFLYCIAGKKFRTYFLLLLSCSKFSNN 1083
            VG  GN+MV +V++  RH R   T  YL+SLAIAD TVL+    P       G  I     A C    ++      ++   I   TVER I +  P KA    TV+RA   ++ V I F  + C L+  +V +    D      Y      ++R+   PI +I    D   +  +P L+ I    +I   L   +   L  Q  T    S  TL    R TS   +P  Q           Q   ML +V  +F L  +P     ++N+ V   Y        + + FLL      T +  N +IN  +Y    +KFR  F  L SC +   N
Sbjct:   43 VGIIGNVMVVLVVFTTRHMRT-PTNCYLVSLAIADLTVLVAAGLPNVSDSLTGTWI--FGQAGCLGITYLQYLGINVSSCSITAFTVERYIAICHPMKAQTVCTVSRAKRIIAGVWI-FTCVYCMLWLFLVDIQVGPDGHVQCGYR-----VKRELYLPIYLI----DFAIFYVIPLLLAIVLYALIARIL---YLSPLPHQPDT----SATTLRRSCRDTSEAARPGRQGRPKSALSSRKQVTKMLAVVVILFALLWMPYRTLVLINSFVSTPY--------LNAWFLLF---CRTCIYANSAINPVIYNAMSQKFRLAFRGLYSCQRLEGN 344
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000009115.1 (SMESG000009115.1)

HSP 1 Score: 781.941 bits (2018), Expect = 0.000e+0
Identity = 405/406 (99.75%), Postives = 406/406 (100.00%), Query Frame = 1 
Query:   19 MYIDENELEAFNNFSTYRQMKYIYVIFPPILLIVGSFGNIMVPIVLYRHSRVISTYVYLISLAIADQTVLIFGTTPKWLQHTFGVNIENSSNATCKLFAFVGMAFSQIAVWLIXXXXXXXXXXXSLPFKAPQHITVTRAVICVSVVTIFFLSINCPLFFTVVLLDSSEDSPENNSYSNSVCDMRRDFQFPITMIWSWFDGLFYSYLPCLXXXXXXXXXXHFLRTAHKRRLLMQCSTVNINSHNTLVNHSRQTSCNYKPANQSSQQLFMLILVSWVFVLTVIPISIFKIVNNIVKKHYPFYLENQEVMSEFLLINTVVETFMTTNHSINFFLYCIAGKKFRTYFLLLLSCSKFSNNSNASIVGASVLLNSNCSRKFVKSPMELPNRTKKILSNDQGREVLIECCTEV 1236
            MYIDENELEAFNNFSTYRQMKYIYVIFPPILLIVGSFGNIMVPIVLYRHSRVISTYVYLISLAIADQTVLIFGTTPKWLQHTFG+NIENSSNATCKLFAFVGMAFSQIAVWLIVVVTVERMIVVSLPFKAPQHITVTRAVICVSVVTIFFLSINCPLFFTVVLLDSSEDSPENNSYSNSVCDMRRDFQFPITMIWSWFDGLFYSYLPCLIIIFANIIIIHFLRTAHKRRLLMQCSTVNINSHNTLVNHSRQTSCNYKPANQSSQQLFMLILVSWVFVLTVIPISIFKIVNNIVKKHYPFYLENQEVMSEFLLINTVVETFMTTNHSINFFLYCIAGKKFRTYFLLLLSCSKFSNNSNASIVGASVLLNSNCSRKFVKSPMELPNRTKKILSNDQGREVLIECCTEV
Sbjct:    1 MYIDENELEAFNNFSTYRQMKYIYVIFPPILLIVGSFGNIMVPIVLYRHSRVISTYVYLISLAIADQTVLIFGTTPKWLQHTFGINIENSSNATCKLFAFVGMAFSQIAVWLIVVVTVERMIVVSLPFKAPQHITVTRAVICVSVVTIFFLSINCPLFFTVVLLDSSEDSPENNSYSNSVCDMRRDFQFPITMIWSWFDGLFYSYLPCLIIIFANIIIIHFLRTAHKRRLLMQCSTVNINSHNTLVNHSRQTSCNYKPANQSSQQLFMLILVSWVFVLTVIPISIFKIVNNIVKKHYPFYLENQEVMSEFLLINTVVETFMTTNHSINFFLYCIAGKKFRTYFLLLLSCSKFSNNSNASIVGASVLLNSNCSRKFVKSPMELPNRTKKILSNDQGREVLIECCTEV 406
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000042142.1 (SMESG000042142.1)

HSP 1 Score: 144.821 bits (364), Expect = 2.948e-38
Identity = 117/352 (33.24%), Postives = 196/352 (55.68%), Query Frame = 1 
Query:   82 YIYVIFPPILLIVGSFGNIMVPIVLYRHSRV-ISTYVYLISLAIADQTVLIFGTTPKWLQHTFGVNIENSSNATCKLFAFVGMAFSQIAVWLIXXXXXXXXXXXSLPFKAPQHITVTRA-VICVSVVTIFFLSINCPLFFTVVLLDSSEDSPENNSYSNSVCDMRRDFQF-----PITMIWSWFDGLFYSYLPCLXXXXXXXXXXHFLRTAHKRRLLMQCSTVNINSHNTLVNHSRQTSCNYK-----PANQSSQQL-FMLILVSWVFVLTVIPISIFKIVNNIVKKHYPFYLENQEVMSEFLLINTVVETFMTTNHSINFFLYCIAGKKFRTYFLLLLSC---SKFSNNSN 1089
            +++++ P  ++ +GS GN +  +VL R S   IS+Y+YL +LAI D+ +L+ G   KW++H    ++EN S + CKLF  +G++ S I+VWLIV +TVER++++  PF+A ++   +RA  I VS++ I F + +C  F TV L + +  +   N  S+   +  +  QF       T  W + DG FYS++P  ++I  N+II+  +  A  R +       N + + TL     +T    +       N+ ++QL  ML++VS+ F++T  P  I K++  I  K YP        +++ +L++ + E  M  NH+INF+LYC  G KFR   + +L C   SKFS  +N
Sbjct:   69 WLWMLIPIFIVAMGSIGNFLSAVVLCRKSMSHISSYIYLATLAIFDELILLCGLFRKWIEHVTDWSLENHSISFCKLFQVIGVSSSFISVWLIVTLTVERVLIIKRPFEASKYAKASRAKYIIVSLIIISF-TTSCHFFETVTLQNLNHKNVNTNFSSDKGSNSIKKCQFKTEYTKFTNAWFFIDGAFYSWIPLFLLIINNLIILSEIYKA--RNIHNSMINTNHDENKTLGTSIVRTQLPRRMKESSSRNRETKQLTVMLLIVSFSFLITTSPFVILKLL--IKLKGYP---NGDRKLAQLVLLDGIFEMLMYVNHAINFYLYCATGNKFRQQLIKILFCRRSSKFSTTTN 412
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000063133.1 (SMESG000063133.1)

HSP 1 Score: 142.124 bits (357), Expect = 8.051e-37
Identity = 114/354 (32.20%), Postives = 190/354 (53.67%), Query Frame = 1 
Query:   85 IYVIFPPILLIVGSFGNIMVPIVLYRHSRV-ISTYVYLISLAIADQTVLIFGTTPKWLQHTFGVNIENSSNATCKLFAFVGMAFSQIAVWLIXXXXXXXXXXXSLPFKAPQHITVTRAVICVSVVTIFFLSINCPLFFTVVLLDSSEDSP------ENNSYSNSVCDMRRDFQFPITMIWSWFDGLFYSYLPCLXXXXXXXXXXHFLRTAHKRRLLMQC-------STVNINSHNTLVNHSR------QTSCNYKPANQSSQQLFMLILVSWVFVLTVIPISIFK--IVNNIVKKHYPFYLENQEVMSEFLLINTVVETFMTTNHSINFFLYCIAGKKFRTY---FLLLLSCSK 1071
            I+  FPPIL ++G+ GN     VL +   + +STY YL  L   DQ++LI G   +W+  TFG + EN+    C++F F+G+A S ++VWLIVVVTVER+IV+ LP +   ++++ +  + +  + I  ++I+   FF  V L+  ++S       E+ ++S  +CD + ++      IW++ D   YS LP +++I  N++I H +  A + R  M          T +INS+ +    +R      + +    P  ++ Q   ML++VS  F++T  P+ + K  I  N+ +     Y+   E      L++T+ E  M TNH+INF LYC +GKKFR +   F   + C K
Sbjct:  190 IWKAFPPILFLLGTLGNTTAFCVLVQRKLIRVSTYYYLAVLTCFDQSILIIGLLRRWVDKTFGFSSENNWLVCCQVFQFIGVATSLMSVWLIVVVTVERLIVIKLPLRVHSYVSIKKTKLIILSLFIITMTISSH-FFETVTLNRRKNSKTLQMTTESKNHSFLICDFKTEYA-TFAKIWTFLDAFLYSCLPLVLMIVMNVVIGHGIYQADRSRGEMISMNSKDLRKTKSINSNKSTRTGNRIYGFTPRQAAPPLPNRETRQLTIMLLVVSCTFLITTTPLVLLKFFIKLNLYRNSSTSYITKLE------LVDTIFEMLMYTNHAINFLLYCASGKKFRYHVKRFFESICCGK 535
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000020718.1 (SMESG000020718.1)

HSP 1 Score: 135.191 bits (339), Expect = 6.308e-35
Identity = 115/334 (34.43%), Postives = 178/334 (53.29%), Query Frame = 1 
Query:   82 YIYVIFPPILLIVGSFGNIMVPIVLYRHS-RVISTYVYLISLAIADQTVLIFGTTPKWLQHTFGVNIENSSNATCKLFAFVGMAFSQIAVWLIXXXXXXXXXXXSLPFKAPQHITVTRA-VICVSVVTIFFLSINCPLFFTVVLLDSSE--DSPENNSYSNSVCDMRRDFQFPITMIWSWFDGLFYSYLPCLXXXXXXXXXXHFLRTAHKRRLLMQCSTVNINSHNTLVNHSRQTSCNYKPANQSSQQL-FMLILVSWVFVLTVIPISIFKIVNNIVKK---------HYPFYLENQEVMSEFLLINTVVETFMTTNHSINFFLYCIAGKKFRT 1041
            YI  I P I+L  G+ GN+M  IVL   + + +ST++YL  LAI DQ VLIFG   +W+ +     IEN +   C L  + G + S ++VWLIV VT+ER IV+S PFKA   I  +RA VI +S+ ++  + +NC   FT+ L +S++  +S +N    N VC     ++     +W   D + YS+LP + I   N+II   ++    RR      T+N           R     Y+  ++S++QL  ML+++S  F++T  PI I K++  + K          H P   +   V S+F   +++ E  M  NH++NF+LYC +G KFR 
Sbjct:   82 YILTIIPAIILFFGTIGNVMSFIVLCNFAGKTVSTFIYLSLLAIVDQFVLIFGLLKRWVDYLLKRKIENRNKTFCILSQYFGTSASVLSVWLIVAVTLERAIVISFPFKAHNLIQKSRAIVISISMASVIMI-LNCHFIFTLDLTNSTQLFESTDN----NFVCGFSESYR-NFKTVWLLIDAIIYSFLPFIFIFALNVII--LIKVCQARRTRQSMMTLN-----------RGQKSVYR--SESTRQLTIMLLMISGTFLITTTPIFIVKMLYVVPKAFSKAIPKTFHAPGIRD--AVASQF--ADSIAEILMHLNHALNFYLYCASGNKFRA 390
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000075029.1 (SMESG000075029.1)

HSP 1 Score: 133.65 bits (335), Expect = 2.428e-34
Identity = 110/336 (32.74%), Postives = 170/336 (50.60%), Query Frame = 1 
Query:   79 KYIYVIFPPILLIVGSFGNIMVPIVLYRHSRVISTYVYLISLAIADQTVLIFGTTPKWLQHTFGVNIENSSNATCKLFAFVGMAFSQIAVWLIXXXXXXXXXXXSLPFKAPQHITVTRAVICVSVVTIFFLSINCPLFFTVVLLDSSEDSPE-------NNSYSN-SVCDMRRDFQFPITMIWSWFDGLFYSYLPCLXXXXXXXXXXHFLRTAHKRR--LLMQCSTVNINSHNTLVNHSRQTSCNYKPANQSSQQL-FMLILVSWVFVLTVIPISIFKIVNNIVKKHYPFYLENQEVMSE-----FLLINTVVETFMTTNHSINFFLYCIAGKKFR 1038
            KY++ I P ILLI+G+ GN    I+L +  R +S+YVYL +LA+ADQ VLI G     +       +E+S + TC L   +G + S ++ WLIV VT ER IV+  PF + +  +  R  + V       +S+ C L  +  LL    ++ +       N S  N S C +R +     +  W W DGL YSYLP  +I+  N +I+  +R A + R  L+ +C   N          +   S N +  ++ + QL  ML  +S  F++T  PI + KIVN         + +N++ + +       L++++ E  M  NHS NF+LYC  G KFR
Sbjct:   79 KYLWKIVPLILLILGTIGNCTSFIILTK--RRVSSYVYLSALAMADQGVLITGLMRHCIDRILDYRLEDSHHWTCVLTQLIGSSLSYLSAWLIVAVTAERAIVIMFPFSSIRLYSRFRETLVV-----LLISLACLLASSHFLLSVRLETGQMYRFNLNNGSVQNYSQCQLRNELH-SFSKAWYWLDGLLYSYLPFFLILCLNGLIVSHVRKAREHRNILVSRCPQSNYAQIKDCSVRNLSHSVNTQAGSRQTFQLTLMLFSISACFLITTCPIVVMKIVN---------FTQNRDTLDQRGSALHQLLDSIAELLMYLNHSANFYLYCATGSKFR 397
The following BLAST results are available for this feature:
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4
Match NameE-valueIdentityDescription
SPR3.568e-925.41gene:FBgn0029768 transcript:FBtr0344824[more]
SPR3.568e-925.41gene:FBgn0029768 transcript:FBtr0339781[more]
SPR3.568e-925.41gene:FBgn0029768 transcript:FBtr0070778[more]
CNMaR4.112e-728.81gene:FBgn0053696 transcript:FBtr0091684[more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2T7NJU41.944e-4133.79G_PROTEIN_RECEP_F1_2 domain-containing protein OS=... [more]
A0A1S3J0N53.720e-3935.29FMRFamide receptor-like OS=Lingula unguis OX=7574 ... [more]
A0A210QEM01.154e-3730.47Thyrotropin-releasing hormone receptor OS=Mizuhope... [more]
A0A210QEF51.940e-3730.75Thyrotropin-releasing hormone receptor OS=Mizuhope... [more]
A0A210PZW93.803e-3732.21Thyrotropin-releasing hormone receptor OS=Mizuhope... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
drd2a6.477e-626.63D(2)-like dopamine receptor [Source:NCBI gene;Acc:... [more]
drd2a6.750e-626.63D(2)-like dopamine receptor [Source:NCBI gene;Acc:... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
trhr24.970e-928.36TRHR2 protein [Source:NCBI gene;Acc:100533510][more]
trhr22.076e-828.53TRHR2 protein [Source:NCBI gene;Acc:100533510][more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000009115.10.000e+099.75SMESG000009115.1[more]
SMESG000042142.12.948e-3833.24SMESG000042142.1[more]
SMESG000063133.18.051e-3732.20SMESG000063133.1[more]
SMESG000020718.16.308e-3534.43SMESG000020718.1[more]
SMESG000075029.12.428e-3432.74SMESG000075029.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30020621 ID=SMED30020621|Name=G_PROTEIN_RECEP_F1_2 domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1325bp
AAGATTCAACTATAGAAAATGTATATTGATGAAAACGAATTGGAAGCGTT
TAACAATTTTTCAACCTACAGACAAATGAAATATATTTACGTTATTTTTC
CACCGATTTTGTTAATAGTAGGCTCTTTCGGAAACATCATGGTACCGATT
GTTCTCTACAGACATTCTCGAGTCATTTCCACATATGTCTATCTCATATC
TTTGGCAATAGCTGATCAGACAGTTCTCATCTTTGGTACAACTCCAAAAT
GGCTTCAGCATACTTTTGGAGTTAACATAGAAAACTCATCGAATGCTACT
TGTAAACTGTTTGCTTTTGTTGGAATGGCATTTTCTCAAATTGCAGTTTG
GTTGATAGTTGTTGTAACCGTTGAAAGGATGATTGTTGTGTCCTTGCCCT
TTAAAGCTCCTCAGCATATCACAGTCACAAGAGCTGTGATTTGTGTATCA
GTTGTGACAATTTTTTTCCTCTCAATCAACTGCCCATTGTTTTTTACGGT
GGTTTTACTAGATTCGTCAGAAGATTCGCCAGAAAATAATTCGTATTCTA
ATTCAGTATGCGATATGCGACGAGATTTCCAATTTCCAATTACAATGATT
TGGTCATGGTTTGATGGATTGTTTTACAGCTATTTGCCATGTTTGATTAT
AATATTTGCGAATATAATTATCATACACTTTTTAAGGACAGCACATAAAA
GACGTTTATTAATGCAATGTTCTACTGTTAATATAAATTCTCACAATACG
CTTGTAAATCATTCCAGACAAACCAGCTGCAACTATAAACCGGCCAACCA
ATCTTCCCAACAACTCTTCATGTTGATTCTCGTTTCGTGGGTCTTCGTTC
TCACTGTCATACCGATCTCAATTTTCAAAATTGTCAACAATATAGTAAAG
AAACACTATCCATTCTATCTTGAGAATCAAGAAGTCATGTCTGAATTTTT
ACTGATTAACACGGTTGTCGAAACATTCATGACGACAAACCATTCGATCA
ATTTCTTTTTATACTGCATTGCCGGAAAAAAGTTCCGAACCTATTTTTTA
CTGTTGTTAAGTTGTTCCAAGTTCTCCAACAACAGCAATGCGTCGATTGT
TGGTGCAAGTGTTTTACTAAATTCAAATTGCTCGAGAAAATTCGTGAAAA
GTCCAATGGAATTGCCAAACAGAACTAAGAAGATCCTTTCCAATGATCAA
GGTCGAGAAGTGTTAATCGAGTGCTGCACGGAAGTGTAAAACGGTTTCAT
CCCGTCCGGGTCAACAAACTCACTCATATATCATAGTTTGTGAAATCATG
AGATTTATGTAATTTAATCATGTAG
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protein sequence of SMED30020621-orf-1

>SMED30020621-orf-1 ID=SMED30020621-orf-1|Name=SMED30020621-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=407bp
MYIDENELEAFNNFSTYRQMKYIYVIFPPILLIVGSFGNIMVPIVLYRHS
RVISTYVYLISLAIADQTVLIFGTTPKWLQHTFGVNIENSSNATCKLFAF
VGMAFSQIAVWLIVVVTVERMIVVSLPFKAPQHITVTRAVICVSVVTIFF
LSINCPLFFTVVLLDSSEDSPENNSYSNSVCDMRRDFQFPITMIWSWFDG
LFYSYLPCLIIIFANIIIIHFLRTAHKRRLLMQCSTVNINSHNTLVNHSR
QTSCNYKPANQSSQQLFMLILVSWVFVLTVIPISIFKIVNNIVKKHYPFY
LENQEVMSEFLLINTVVETFMTTNHSINFFLYCIAGKKFRTYFLLLLSCS
KFSNNSNASIVGASVLLNSNCSRKFVKSPMELPNRTKKILSNDQGREVLI
ECCTEV*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000418head
PLANA:0002028dorsal-ventral muscle cell
Vocabulary: INTERPRO
TermDefinition
IPR000276GPCR_Rhodpsn
IPR017452GPCR_Rhodpsn_7TM
Vocabulary: molecular function
TermDefinition
GO:0004930G-protein coupled receptor activity
GO:0004871signal transducer activity
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0016020membrane
Vocabulary: biological process
TermDefinition
GO:0007186G-protein coupled receptor signaling pathway
GO:0007165signal transduction
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000276G protein-coupled receptor, rhodopsin-likePRINTSPR00237GPCRRHODOPSNcoord: 314..340
score: 23.38
coord: 102..124
score: 16.27
coord: 55..76
score: 29.4
coord: 265..289
score: 20.91
coord: 23..47
score: 21.62
IPR000276G protein-coupled receptor, rhodopsin-likePFAMPF000017tm_1coord: 38..298
e-value: 2.8E-16
score: 59.6
NoneNo IPR availableGENE3DG3DSA:1.20.1070.10coord: 10..356
e-value: 1.0E-45
score: 158.1
NoneNo IPR availablePANTHERPTHR46641FAMILY NOT NAMEDcoord: 21..364
NoneNo IPR availablePANTHERPTHR46641:SF12CNMAMIDE RECEPTORcoord: 21..364
NoneNo IPR availableCDDcd149787tmA_FMRFamide_R-likecoord: 22..341
e-value: 1.65632E-31
score: 119.66
NoneNo IPR availableSUPERFAMILYSSF81321Family A G protein-coupled receptor-likecoord: 12..356
NoneNo IPR availableTMHMMTMhelixcoord: 266..288
NoneNo IPR availableTMHMMTMhelixcoord: 52..74
NoneNo IPR availableTMHMMTMhelixcoord: 310..332
NoneNo IPR availableTMHMMTMhelixcoord: 23..45
NoneNo IPR availableTMHMMTMhelixcoord: 200..222
NoneNo IPR availableTMHMMTMhelixcoord: 140..162
NoneNo IPR availableTMHMMTMhelixcoord: 97..119
IPR017452GPCR, rhodopsin-like, 7TMPROSITEPS50262G_PROTEIN_RECEP_F1_2coord: 38..332
score: 25.828