prohibitin-1

Overview


Name	prohibitin-1 (AFJ24824.1)
Smed ID	SMED30020615
Length (bp)	989

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of prohibitin-1 (SMED30020615) t-SNE clustered cells

Violin plots show distribution of expression levels for prohibitin-1 (SMED30020615) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of prohibitin-1 (SMED30020615) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for prohibitin-1 (SMED30020615) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30020615

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 14

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
X1 cell	SMED30020615	SMESG000021272.1	SmedASXL_018897	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X2 cell	SMED30020615	SMESG000021272.1	SmedASXL_018897	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
pharynx	SMED30020615	SMESG000021272.1	dd_Smed_v4_1089_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30020615	SMESG000021272.1	dd_Smed_v4_1089_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30020615	SMESG000021272.1	dd_Smed_v4_1089_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30020615	SMESG000021272.1	dd_Smed_v4_1089_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30020615	SMESG000021272.1	dd_Smed_v4_1089_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30020615	SMESG000021272.1	dd_Smed_v4_1089_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30020615	SMESG000021272.1	dd_Smed_v4_1089_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30020615	SMESG000021272.1	dd_Smed_v4_1089_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020615	SMESG000021272.1	Contig39559	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020615	SMESG000021272.1	Contig39559	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020615	SMESG000049778.1 SMESG000048378.1 SMESG000039423.1 SMESG000024543.1 SMESG000022136.1 SMESG000021272.1 SMESG000002434.1	Contig13665	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020615	SMESG000049778.1 SMESG000048378.1 SMESG000039423.1 SMESG000024543.1 SMESG000022136.1 SMESG000021272.1 SMESG000002434.1	Contig13665	uc_Smed_v2	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of prohibitin-1 vs. Ensembl Human
Match: PHB2 (prohibitin 2 [Source:HGNC Symbol;Acc:HGNC:30306])

HSP 1 Score: 350.903 bits (899), Expect = 7.608e-121
Identity = 168/261 (64.37%), Postives = 222/261 (85.06%), Query Frame = 1

Query:  148 KSFYTVDGGQRSIIFSRFGGIKEN-IYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFNESVEHIGKRK 927
            +S +TV+GG R+I F+R GG++++ I AEGLH RIP  QYPII+D+R+RPR ISSPTGSKDLQMVNISLRVLSRP+  ++P +Y+ +G DY+E+VLPSI NEVLK+VVAKFNA QLITQR QVSLLIR+ L ERAKDF++I+DDV+IT+LSFSR+Y+ AVE KQ++QQEAQRAQF V +AKQE++QKIV AEGEA+AA ++G+AL+++ GY+KLRKI+AA+ I++T++TSQN+ YL A+ L+LNL ++SF  S   I  +K
Sbjct:   38 ESVFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSMYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILDDVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLGEALSKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRSDSLIKGKK 298

[Close]

BLAST of prohibitin-1 vs. Ensembl Human
Match: PHB2 (prohibitin 2 [Source:HGNC Symbol;Acc:HGNC:30306])

HSP 1 Score: 350.132 bits (897), Expect = 1.500e-120
Identity = 167/261 (63.98%), Postives = 222/261 (85.06%), Query Frame = 1

Query:  148 KSFYTVDGGQRSIIFSRFGGIKEN-IYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFNESVEHIGKRK 927
            +S +TV+GG R+I F+R GG++++ I AEGLH RIP  QYPII+D+R+RPR ISSPTGSKDLQMVNISLRVLSRP+  ++P +Y+ +G DY+E+VLPSI NEVLK+VVAKFNA QLITQR QVSLLIR+ L ERAKDF++I+DDV+IT+LSFSR+Y+ AVE KQ++QQEAQRAQF V +AKQE++QKIV AEGEA+AA ++G+AL+++ GY+KLRKI+AA+ I++T++TSQN+ YL A+ L+LNL ++SF    + + K K
Sbjct:   38 ESVFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSMYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILDDVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLGEALSKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRGSDSLIKGK 298

[Close]

BLAST of prohibitin-1 vs. Ensembl Human
Match: PHB2 (prohibitin 2 [Source:HGNC Symbol;Acc:HGNC:30306])

HSP 1 Score: 320.472 bits (820), Expect = 2.414e-109
Identity = 152/226 (67.26%), Postives = 198/226 (87.61%), Query Frame = 1

Query:  148 KSFYTVDGGQRSIIFSRFGGIKEN-IYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIART 822
            +S +TV+GG R+I F+R GG++++ I AEGLH RIP  QYPII+D+R+RPR ISSPTGSKDLQMVNISLRVLSRP+  ++P +Y+ +G DY+E+VLPSI NEVLK+VVAKFNA QLITQR QVSLLIR+ L ERAKDF++I+DDV+IT+LSFSR+Y+ AVE KQ++QQEAQRAQF V +AKQE++QKIV AEGEA+AA ++G+AL+++ GY+KLRKI+AA+ I++T
Sbjct:   38 ESVFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSMYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILDDVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLGEALSKNPGYIKLRKIRAAQNISKT 263

[Close]

BLAST of prohibitin-1 vs. Ensembl Human
Match: PHB2 (prohibitin 2 [Source:HGNC Symbol;Acc:HGNC:30306])

HSP 1 Score: 279.256 bits (713), Expect = 3.720e-93
Identity = 141/261 (54.02%), Postives = 188/261 (72.03%), Query Frame = 1

Query:  148 KSFYTVDGGQRSIIFSRFGGIKEN-IYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFNESVEHIGKRK 927
            +S +TV+GG R+I F+R GG++++ I AEGLH RIP  QYPII+D+R+RPR ISSPTGSKDLQMVNISLRVLSRP+  ++P +Y+ +G DY+E+VLPSI NEVLK+VVAKFNA QLITQR QVSLLIR+ L ERAKDF++I+DDV+IT+LSFSR+Y+ AVE KQ+                                      AL+++ GY+KLRKI+AA+ I++T++TSQN+ YL A+ L+LNL ++SF    + + K K
Sbjct:   38 ESVFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSMYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILDDVAITELSFSREYTAAVEAKQV--------------------------------------ALSKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRGSDSLIKGK 260

[Close]

BLAST of prohibitin-1 vs. Ensembl Human
Match: PHB (prohibitin [Source:HGNC Symbol;Acc:HGNC:8912])

HSP 1 Score: 263.848 bits (673), Expect = 5.870e-87
Identity = 129/248 (52.02%), Postives = 187/248 (75.40%), Query Frame = 1

Query:  142 MSKSFYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDAL-TQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNAN-TLMLNL 879
            ++ + Y VD G R++IF RF G+++ +  EG H  IP +Q PIIFD RSRPR +   TGSKDLQ VNI+LR+L RP  +++P I+ +IGEDYDE+VLPSI+ E+LK+VVA+F+AG+LITQRE VS  +   L ERA  F +I+DDVS+T L+F ++++EAVE KQ++QQEA+RA+F V +A+Q+++  I++AEG+++AA LI ++L T   G ++LRK++AAE IA  LS S+N  YL A  +++L L
Sbjct:   23 VNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYLPAGQSVLLQL 270

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BLAST of prohibitin-1 vs. Ensembl Celegans
Match: phb-2 (Mitochondrial prohibitin complex protein 2 [Source:UniProtKB/Swiss-Prot;Acc:P50093])

HSP 1 Score: 331.257 bits (848), Expect = 1.648e-113
Identity = 156/249 (62.65%), Postives = 200/249 (80.32%), Query Frame = 1

Query:  148 KSFYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSF 894
            +S +TV+ G R+I+F+R GG+  ++Y EGLH RIP  QYPII+D+R+RP  I SPTGSKDLQMVNI LRVLSRP+   +  IYR +G++++E+VLPSI NEVLK VVAKFNA QLITQR+QVS+L+RK LIERA DFNII+DDVS+T+L+FS QYS AVE KQ++ QEAQRA F V RAKQ++Q+KIV AEGEA++A L+G+A+    G+LKLRKI+AA+KIAR +S S NK YL    LMLN+ +  +
Sbjct:   38 QSMFTVEAGHRAIMFNRIGGLSTDLYKEGLHFRIPWFQYPIIYDIRARPNQIRSPTGSKDLQMVNIGLRVLSRPNPEHLVHIYRTLGQNWEERVLPSICNEVLKGVVAKFNASQLITQRQQVSMLVRKTLIERALDFNIILDDVSLTELAFSPQYSAAVEAKQVAAQEAQRATFYVERAKQQKQEKIVQAEGEAESAKLLGEAMKNDPGFLKLRKIRAAQKIARIVSESGNKTYLPTGGLMLNIADTDY 286

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Query:  148 KSFYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSF 894
            +S +TV+ G R+I+F+R GG+  ++Y EGLH RIP  QYPII+D+R+RP  I SPTGSKDLQMVNI LRVLSRP+   +  IYR +G++++E+VLPSI NEVLK VVAKFNA QLITQR+QVS+L+RK LIERA DFNII+DDVS+T+L+FS QYS AVE KQ++ QEAQRA F V RAKQ++Q+KIV AEGEA++A L+G+A+    G+LKLRKI+AA+KIAR +S S NK YL    LMLN+ +  +
Sbjct:   38 QSMFTVEAGHRAIMFNRIGGLSTDLYKEGLHFRIPWFQYPIIYDIRARPNQIRSPTGSKDLQMVNIGLRVLSRPNPEHLVHIYRTLGQNWEERVLPSICNEVLKGVVAKFNASQLITQRQQVSMLVRKTLIERALDFNIILDDVSLTELAFSPQYSAAVEAKQVAAQEAQRATFYVERAKQQKQEKIVQAEGEAESAKLLGEAMKNDPGFLKLRKIRAAQKIARIVSESGNKTYLPTGGLMLNIADTDY 286

[Close]

BLAST of prohibitin-1 vs. Ensembl Celegans
Match: phb-1 (Mitochondrial prohibitin complex protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q9BKU4])

HSP 1 Score: 245.743 bits (626), Expect = 3.087e-80
Identity = 127/245 (51.84%), Postives = 179/245 (73.06%), Query Frame = 1

Query:  151 SFYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSS-GYLKLRKIKAAEKIARTLSTSQNKAYLNAN-TLMLNL 879
            + Y VDGGQR++IF RF G+K  +  EG H  IP +Q PIIFD+RS PR +++ TGSKDLQ VNI+LR+L RP   ++P+IY NIG DY E+VLPSI+NEVLKAVVA+F+A ++ITQRE VS      L ERA  F +++DD++IT L+F R+++EAVE KQ++QQEA++A++ V +A+Q +   +  AEG+AQAA L+  A   +  G ++LRKI+AAE+IA  ++ ++N  YL  N   +LNL
Sbjct:   29 ALYNVDGGQRAVIFDRFSGVKNEVVGEGTHFLIPWVQKPIIFDIRSTPRAVTTITGSKDLQNVNITLRILHRPSPDRLPNIYLNIGLDYAERVLPSITNEVLKAVVAQFDAHEMITQREVVSQRASVALRERAAQFGLLLDDIAITHLNFGREFTEAVEMKQVAQQEAEKARYLVEKAEQMKIAAVTTAEGDAQAAKLLAKAFASAGDGLVELRKIEAAEEIAERMAKNKNVTYLPGNQQTLLNL 273

[Close]

BLAST of prohibitin-1 vs. Ensembl Fly
Match: Phb2 (gene:FBgn0010551 transcript:FBtr0086614)

HSP 1 Score: 372.474 bits (955), Expect = 1.100e-129
Identity = 174/261 (66.67%), Postives = 223/261 (85.44%), Query Frame = 1

Query:  145 SKSFYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFNESVEHIGKRK 927
            S+S YTV+GG R+IIFSR GGI+ +IY+EGLH+RIP  QYPII+D+RSRPR ISSPTGSKDLQM+NISLRVLSRPD   +P +++ +G DYDEKVLPSI NEVLK+V+AKFNA QLITQR+QVSLLIRK L+ERA+DFNII+DDVS+T+LSF ++Y+ A+E KQ++QQEAQRA F V RAKQE+QQKIV AEGEA+AA ++G A+ Q+  YLKLRK++AA+ IART+++SQNK YL+A++LMLN+ +  F++  E + K K
Sbjct:   39 SQSLYTVEGGHRAIIFSRLGGIQSDIYSEGLHVRIPWFQYPIIYDIRSRPRKISSPTGSKDLQMINISLRVLSRPDSLNLPYLHKQLGVDYDEKVLPSICNEVLKSVIAKFNASQLITQRQQVSLLIRKELVERARDFNIILDDVSLTELSFGKEYTAAIEAKQVAQQEAQRAVFFVERAKQEKQQKIVQAEGEAEAAKMLGLAVKQNPAYLKLRKLRAAQSIARTIASSQNKVYLSADSLMLNIQDSGFDDMTEKVYKSK 299

[Close]

BLAST of prohibitin-1 vs. Ensembl Fly
Match: Phb2 (gene:FBgn0010551 transcript:FBtr0086615)

HSP 1 Score: 372.474 bits (955), Expect = 1.100e-129
Identity = 174/261 (66.67%), Postives = 223/261 (85.44%), Query Frame = 1

Query:  145 SKSFYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFNESVEHIGKRK 927
            S+S YTV+GG R+IIFSR GGI+ +IY+EGLH+RIP  QYPII+D+RSRPR ISSPTGSKDLQM+NISLRVLSRPD   +P +++ +G DYDEKVLPSI NEVLK+V+AKFNA QLITQR+QVSLLIRK L+ERA+DFNII+DDVS+T+LSF ++Y+ A+E KQ++QQEAQRA F V RAKQE+QQKIV AEGEA+AA ++G A+ Q+  YLKLRK++AA+ IART+++SQNK YL+A++LMLN+ +  F++  E + K K
Sbjct:   39 SQSLYTVEGGHRAIIFSRLGGIQSDIYSEGLHVRIPWFQYPIIYDIRSRPRKISSPTGSKDLQMINISLRVLSRPDSLNLPYLHKQLGVDYDEKVLPSICNEVLKSVIAKFNASQLITQRQQVSLLIRKELVERARDFNIILDDVSLTELSFGKEYTAAIEAKQVAQQEAQRAVFFVERAKQEKQQKIVQAEGEAEAAKMLGLAVKQNPAYLKLRKLRAAQSIARTIASSQNKVYLSADSLMLNIQDSGFDDMTEKVYKSK 299

[Close]

BLAST of prohibitin-1 vs. Ensembl Fly
Match: Phb2 (gene:FBgn0010551 transcript:FBtr0086616)

HSP 1 Score: 372.474 bits (955), Expect = 1.100e-129
Identity = 174/261 (66.67%), Postives = 223/261 (85.44%), Query Frame = 1

Query:  145 SKSFYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFNESVEHIGKRK 927
            S+S YTV+GG R+IIFSR GGI+ +IY+EGLH+RIP  QYPII+D+RSRPR ISSPTGSKDLQM+NISLRVLSRPD   +P +++ +G DYDEKVLPSI NEVLK+V+AKFNA QLITQR+QVSLLIRK L+ERA+DFNII+DDVS+T+LSF ++Y+ A+E KQ++QQEAQRA F V RAKQE+QQKIV AEGEA+AA ++G A+ Q+  YLKLRK++AA+ IART+++SQNK YL+A++LMLN+ +  F++  E + K K
Sbjct:   39 SQSLYTVEGGHRAIIFSRLGGIQSDIYSEGLHVRIPWFQYPIIYDIRSRPRKISSPTGSKDLQMINISLRVLSRPDSLNLPYLHKQLGVDYDEKVLPSICNEVLKSVIAKFNASQLITQRQQVSLLIRKELVERARDFNIILDDVSLTELSFGKEYTAAIEAKQVAQQEAQRAVFFVERAKQEKQQKIVQAEGEAEAAKMLGLAVKQNPAYLKLRKLRAAQSIARTIASSQNKVYLSADSLMLNIQDSGFDDMTEKVYKSK 299

[Close]

BLAST of prohibitin-1 vs. Ensembl Fly
Match: Phb2 (gene:FBgn0010551 transcript:FBtr0112863)

HSP 1 Score: 372.474 bits (955), Expect = 1.100e-129
Identity = 174/261 (66.67%), Postives = 223/261 (85.44%), Query Frame = 1

Query:  145 SKSFYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFNESVEHIGKRK 927
            S+S YTV+GG R+IIFSR GGI+ +IY+EGLH+RIP  QYPII+D+RSRPR ISSPTGSKDLQM+NISLRVLSRPD   +P +++ +G DYDEKVLPSI NEVLK+V+AKFNA QLITQR+QVSLLIRK L+ERA+DFNII+DDVS+T+LSF ++Y+ A+E KQ++QQEAQRA F V RAKQE+QQKIV AEGEA+AA ++G A+ Q+  YLKLRK++AA+ IART+++SQNK YL+A++LMLN+ +  F++  E + K K
Sbjct:   39 SQSLYTVEGGHRAIIFSRLGGIQSDIYSEGLHVRIPWFQYPIIYDIRSRPRKISSPTGSKDLQMINISLRVLSRPDSLNLPYLHKQLGVDYDEKVLPSICNEVLKSVIAKFNASQLITQRQQVSLLIRKELVERARDFNIILDDVSLTELSFGKEYTAAIEAKQVAQQEAQRAVFFVERAKQEKQQKIVQAEGEAEAAKMLGLAVKQNPAYLKLRKLRAAQSIARTIASSQNKVYLSADSLMLNIQDSGFDDMTEKVYKSK 299

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BLAST of prohibitin-1 vs. Ensembl Fly
Match: Phb2 (gene:FBgn0010551 transcript:FBtr0112861)

HSP 1 Score: 371.318 bits (952), Expect = 3.491e-129
Identity = 173/259 (66.80%), Postives = 222/259 (85.71%), Query Frame = 1

Query:  145 SKSFYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFNESVEHIGK 921
            S+S YTV+GG R+IIFSR GGI+ +IY+EGLH+RIP  QYPII+D+RSRPR ISSPTGSKDLQM+NISLRVLSRPD   +P +++ +G DYDEKVLPSI NEVLK+V+AKFNA QLITQR+QVSLLIRK L+ERA+DFNII+DDVS+T+LSF ++Y+ A+E KQ++QQEAQRA F V RAKQE+QQKIV AEGEA+AA ++G A+ Q+  YLKLRK++AA+ IART+++SQNK YL+A++LMLN+ +  F++  E + K
Sbjct:   39 SQSLYTVEGGHRAIIFSRLGGIQSDIYSEGLHVRIPWFQYPIIYDIRSRPRKISSPTGSKDLQMINISLRVLSRPDSLNLPYLHKQLGVDYDEKVLPSICNEVLKSVIAKFNASQLITQRQQVSLLIRKELVERARDFNIILDDVSLTELSFGKEYTAAIEAKQVAQQEAQRAVFFVERAKQEKQQKIVQAEGEAEAAKMLGLAVKQNPAYLKLRKLRAAQSIARTIASSQNKVYLSADSLMLNIQDSGFDDMTEKVYK 297

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BLAST of prohibitin-1 vs. Ensembl Zebrafish
Match: phb2b (prohibitin 2b [Source:ZFIN;Acc:ZDB-GENE-040718-430])

HSP 1 Score: 352.829 bits (904), Expect = 1.192e-121
Identity = 167/249 (67.07%), Postives = 217/249 (87.15%), Query Frame = 1

Query:  157 YTVDGGQRSIIFSRFGGIK-ENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFNE 900
            YTV+GGQR+IIF+R GG++ + +  EGLH RIP  QYPII+D+R+RPR ISS TGSKDLQMVNI+LRVLSRP  + +P +Y+ +G+DYDE+VLPSI NEVLK+VVAKFNA QLITQR QVSLLIR+ L ERAKDFNII+DDV+IT+LSFSR+Y+ AVE KQ++QQEAQRAQF V +AKQE++QKI+ AEGEAQAA ++G+A+T++ GYLKLR+I+AA+ IA+T++ SQNK YL+A++L++NL + SFN+
Sbjct:   49 YTVEGGQRAIIFNRIGGVQLDTVLTEGLHFRIPWFQYPIIYDIRARPRKISSLTGSKDLQMVNIALRVLSRPLASNLPIMYQQLGQDYDERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELFERAKDFNIILDDVAITELSFSREYTAAVEAKQVAQQEAQRAQFFVEKAKQEQKQKIIQAEGEAQAAKMLGEAVTKNPGYLKLRRIRAAQNIAKTVAASQNKVYLSADSLVMNLQDDSFNK 297

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Query:  157 YTVDGGQRSIIFSRFGGIK-ENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFNE 900
            YTV+GGQR+IIF+R GG++ + +  EGLH RIP  QYPII+D+R+RPR ISS TGSKDLQMVNI+LRVLSRP  + +P +Y+ +G+DYDE+VLPSI NEVLK+VVAKFNA QLITQR QVSLLIR+ L ERAKDFNII+DDV+IT+LSFSR+Y+ AVE KQ++QQEAQRAQF V +AKQE++QKI+ AEGEAQAA ++G+A+T++ GYLKLR+I+AA+ IA+T++ SQNK YL+A++L++NL + SFN+
Sbjct:   49 YTVEGGQRAIIFNRIGGVQLDTVLTEGLHFRIPWFQYPIIYDIRARPRKISSLTGSKDLQMVNIALRVLSRPLASNLPIMYQQLGQDYDERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELFERAKDFNIILDDVAITELSFSREYTAAVEAKQVAQQEAQRAQFFVEKAKQEQKQKIIQAEGEAQAAKMLGEAVTKNPGYLKLRRIRAAQNIAKTVAASQNKVYLSADSLVMNLQDDSFNK 297

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Query:  157 YTVDGGQRSIIFSRFGGIK-ENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFNE 900
            YTV+GGQR+IIF+R GG++ + +  EGLH RIP  QYPII+D+R+RPR ISS TGSKDLQMVNI+LRVLSRP  + +P +Y+ +G+DYDE+VLPSI NEVLK+VVAKFNA QLITQR QVSLLIR+ L ERAKDFNII+DDV+IT+LSFSR+Y+ AVE KQ++QQEAQRAQF V +AKQE++QKI+ AEGEAQAA ++G+A+T++ GYLKLR+I+AA+ IA+T++ SQNK YL+A++L++NL + SFN+
Sbjct:   49 YTVEGGQRAIIFNRIGGVQLDTVLTEGLHFRIPWFQYPIIYDIRARPRKISSLTGSKDLQMVNIALRVLSRPLASNLPIMYQQLGQDYDERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELFERAKDFNIILDDVAITELSFSREYTAAVEAKQVAQQEAQRAQFFVEKAKQEQKQKIIQAEGEAQAAKMLGEAVTKNPGYLKLRRIRAAQNIAKTVAASQNKVYLSADSLVMNLQDDSFNK 297

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BLAST of prohibitin-1 vs. Ensembl Zebrafish
Match: phb2a (prohibitin 2a [Source:ZFIN;Acc:ZDB-GENE-030131-3141])

HSP 1 Score: 350.132 bits (897), Expect = 1.167e-120
Identity = 166/248 (66.94%), Postives = 217/248 (87.50%), Query Frame = 1

Query:  157 YTVDGGQRSIIFSRFGGIK-ENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFN 897
            YTV+GGQR++IFSR GG++ + + AEGLH R+P  QYPII+D+R+RPR ISS TGSKDLQMVNI LRVLSRP  +++P +Y+ +G+DYDE+VLPSI NEVLK+VVAKFNA QLITQR QVSLLIR+ LIERAKDFNII+DDV+IT+LSFS++Y+ AVE KQ++QQEAQRAQF V +AKQ+++QKI+ AEGEA+AA ++G A+T++ GYLKLR+I+AA+ IA+T++ SQNK YL+A++L+LNL + SFN
Sbjct:   49 YTVEGGQRAVIFSRIGGMQMDTVLAEGLHFRMPWFQYPIIYDIRARPRKISSLTGSKDLQMVNIGLRVLSRPVASQLPIMYQQLGKDYDERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRDLIERAKDFNIILDDVAITELSFSKEYTAAVEAKQVAQQEAQRAQFFVEKAKQDQRQKIIQAEGEAEAAKMLGQAVTKNPGYLKLRRIRAAQNIAKTVAASQNKVYLSADSLVLNLQDSSFN 296

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BLAST of prohibitin-1 vs. Ensembl Zebrafish
Match: phb (prohibitin [Source:ZFIN;Acc:ZDB-GENE-030131-6577])

HSP 1 Score: 266.544 bits (680), Expect = 2.995e-88
Identity = 127/238 (53.36%), Postives = 183/238 (76.89%), Query Frame = 1

Query:  142 MSKSFYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSS-GYLKLRKIKAAEKIARTLSTSQNKAYL 852
            ++ + Y VD G R++IF RF G+++ +  EG H  IP +Q PIIFD RSRPR +   TGSKDLQ VNI+LR+L RP   ++P I+ +IGEDYDE+VLPSI+ EVLK+VVA+F+AG+LITQRE VS  + + L ERA  F +I+DDVS+T L+F ++++EAVE KQ++QQEA+RA+F V +A+Q++Q  I++AEG++QAA+LI ++L ++  G ++LRK++AAE IA  LS ++N  YL
Sbjct:   22 VNSALYNVDAGHRAVIFDRFRGVQDVVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVAGQLPRIFTSIGEDYDERVLPSITTEVLKSVVARFDAGELITQRELVSRQVSEDLTERASTFGLILDDVSLTHLTFGKEFTEAVEMKQVAQQEAERARFVVEKAEQQKQAAIISAEGDSQAALLIANSLAEAGDGLVELRKLEAAEDIAFQLSRARNVTYL 259

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BLAST of prohibitin-1 vs. Ensembl Xenopus
Match: cgref1 (cell growth regulator with EF-hand domain 1 [Source:Xenbase;Acc:XB-GENE-997667])

HSP 1 Score: 350.903 bits (899), Expect = 9.104e-121
Identity = 166/259 (64.09%), Postives = 220/259 (84.94%), Query Frame = 1

Query:  142 MSKSFYTVDGGQRSIIFSRFGGIKEN-IYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFNESVEHI 915
            + +S +TV+GG R+I F+R GG++++ I AEGLH R P  QYPII+D+R+RPR ISSPTGSKDLQMVNI+LRVLSRP  +++P +Y+ +G DYDE+VLPSI NEVLK+VVAKFNA QLITQR QVSLLIR+ L ERAKDF+II+DDV+IT+LSFSR+Y+ AVE KQ++QQEAQRAQF V +AKQ+++QKIV AEGEA AA +IGDAL+++ GYLKLR+I+AA+ IA+T+++SQN+ YLNA++L+LNL + +F    + +
Sbjct:   36 VKESVFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRFPWFQYPIIYDIRARPRKISSPTGSKDLQMVNITLRVLSRPLASELPFMYQRLGLDYDERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSIILDDVAITELSFSREYTAAVESKQVAQQEAQRAQFLVEKAKQDQKQKIVQAEGEAAAAKMIGDALSKNPGYLKLRRIRAAQSIAKTIASSQNRVYLNADSLVLNLQDDTFTRGSDSL 294

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BLAST of prohibitin-1 vs. Ensembl Xenopus
Match: cgref1 (cell growth regulator with EF-hand domain 1 [Source:Xenbase;Acc:XB-GENE-997667])

HSP 1 Score: 350.132 bits (897), Expect = 1.239e-120
Identity = 166/253 (65.61%), Postives = 218/253 (86.17%), Query Frame = 1

Query:  142 MSKSFYTVDGGQRSIIFSRFGGIKEN-IYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFN 897
            + +S +TV+GG R+I F+R GG++++ I AEGLH R P  QYPII+D+R+RPR ISSPTGSKDLQMVNI+LRVLSRP  +++P +Y+ +G DYDE+VLPSI NEVLK+VVAKFNA QLITQR QVSLLIR+ L ERAKDF+II+DDV+IT+LSFSR+Y+ AVE KQ++QQEAQRAQF V +AKQ+++QKIV AEGEA AA +IGDAL+++ GYLKLR+I+AA+ IA+T+++SQN+ YLNA++L+LNL + +F 
Sbjct:   36 VKESVFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRFPWFQYPIIYDIRARPRKISSPTGSKDLQMVNITLRVLSRPLASELPFMYQRLGLDYDERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSIILDDVAITELSFSREYTAAVESKQVAQQEAQRAQFLVEKAKQDQKQKIVQAEGEAAAAKMIGDALSKNPGYLKLRRIRAAQSIAKTIASSQNRVYLNADSLVLNLQDDTFT 288

[Close]

Query:  142 MSKSFYTVDGGQRSIIFSRFGGIKEN-IYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFN 897
            + +S +TV+GG R+I F+R GG++++ I AEGLH R P  QYPII+D+R+RPR ISSPTGSKDLQMVNI+LRVLSRP  +++P +Y+ +G DYDE+VLPSI NEVLK+VVAKFNA QLITQR QVSLLIR+ L ERAKDF+II+DDV+IT+LSFSR+Y+ AVE KQ++QQEAQRAQF V +AKQ+++QKIV AEGEA AA +IGDAL+++ GYLKLR+I+AA+ IA+T+++SQN+ YLNA++L+LNL + +F 
Sbjct:   36 VKESVFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRFPWFQYPIIYDIRARPRKISSPTGSKDLQMVNITLRVLSRPLASELPFMYQRLGLDYDERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSIILDDVAITELSFSREYTAAVESKQVAQQEAQRAQFLVEKAKQDQKQKIVQAEGEAAAAKMIGDALSKNPGYLKLRRIRAAQSIAKTIASSQNRVYLNADSLVLNLQDDTFT 288

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BLAST of prohibitin-1 vs. Ensembl Xenopus
Match: phb (prohibitin [Source:NCBI gene;Acc:394635])

HSP 1 Score: 259.225 bits (661), Expect = 3.387e-85
Identity = 123/238 (51.68%), Postives = 181/238 (76.05%), Query Frame = 1

Query:  142 MSKSFYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSS-GYLKLRKIKAAEKIARTLSTSQNKAYL 852
            ++ + Y VD G +++IF RF G++E +  EG H  IP +Q PIIFD RSRPR +   TGSKDLQ VNI+LR+L RP   ++P I+ +IGEDYDE+VLPSI+ E+LK+VVA+F+AG+LITQRE VS  + + L+ERA  F +I+DDVS+T L+F ++++EAVE KQ++QQEA+RA+F V +A+Q+++  +++AEG+++AA LI  +L  +  G ++LRK++AAE IA  LS ++N  YL
Sbjct:   23 VNSALYNVDAGHQAVIFDRFRGVQETVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVVTGSKDLQNVNITLRILFRPMGNQLPRIFTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSEDLMERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFIVEKAEQQKKAAVISAEGDSKAAELIATSLADAGDGLIELRKLEAAEDIAYQLSRARNVTYL 260

[Close]

BLAST of prohibitin-1 vs. Ensembl Mouse
Match: Phb2 (prohibitin 2 [Source:MGI Symbol;Acc:MGI:102520])

HSP 1 Score: 350.132 bits (897), Expect = 1.030e-120
Identity = 167/261 (63.98%), Postives = 222/261 (85.06%), Query Frame = 1

Query:  148 KSFYTVDGGQRSIIFSRFGGIKEN-IYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFNESVEHIGKRK 927
            +S +TV+GG R+I F+R GG++++ I AEGLH RIP  QYPII+D+R+RPR ISSPTGSKDLQMVNISLRVLSRP+  ++P +Y+ +G DY+E+VLPSI NEVLK+VVAKFNA QLITQR QVSLLIR+ L ERAKDF++I+DDV+IT+LSFSR+Y+ AVE KQ++QQEAQRAQF V +AKQE++QKIV AEGEA+AA ++G+AL+++ GY+KLRKI+AA+ I++T++TSQN+ YL A+ L+LNL ++SF    + + K K
Sbjct:   38 ESVFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSMYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILDDVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLGEALSKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRGSDSLIKGK 298

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BLAST of prohibitin-1 vs. Ensembl Mouse
Match: Phb (prohibitin [Source:MGI Symbol;Acc:MGI:97572])

HSP 1 Score: 265.388 bits (677), Expect = 1.141e-87
Identity = 130/248 (52.42%), Postives = 187/248 (75.40%), Query Frame = 1

Query:  142 MSKSFYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDAL-TQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNAN-TLMLNL 879
            ++ + Y VD G R++IF RF G+++ +  EG H  IP +Q PIIFD RSRPR +   TGSKDLQ VNI+LR+L RP  +++P IY +IGEDYDE+VLPSI+ E+LK+VVA+F+AG+LITQRE VS  +   L ERA  F +I+DDVS+T L+F ++++EAVE KQ++QQEA+RA+F V +A+Q+++  I++AEG+++AA LI ++L T   G ++LRK++AAE IA  LS S+N  YL A  +++L L
Sbjct:   23 VNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIYTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYLPAGQSVLLQL 270

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BLAST of prohibitin-1 vs. Ensembl Mouse
Match: Phb (prohibitin [Source:MGI Symbol;Acc:MGI:97572])

HSP 1 Score: 221.861 bits (564), Expect = 1.510e-71
Identity = 102/185 (55.14%), Postives = 143/185 (77.30%), Query Frame = 1

Query:  142 MSKSFYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQER 696
            ++ + Y VD G R++IF RF G+++ +  EG H  IP +Q PIIFD RSRPR +   TGSKDLQ VNI+LR+L RP  +++P IY +IGEDYDE+VLPSI+ E+LK+VVA+F+AG+LITQRE VS  +   L ERA  F +I+DDVS+T L+F ++++EAVE KQ++QQEA+RA+F V +A+Q++
Sbjct:   23 VNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIYTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKAEQQK 207

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BLAST of prohibitin-1 vs. Ensembl Mouse
Match: Phb2 (prohibitin 2 [Source:MGI Symbol;Acc:MGI:102520])

HSP 1 Score: 179.489 bits (454), Expect = 1.140e-55
Identity = 98/207 (47.34%), Postives = 131/207 (63.29%), Query Frame = 1

Query:  307 SPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFNESVEHIGKRK 927
            SPTGSKDLQMVNISLRVLSRP+  ++P +Y+ +G DY+E+VLPSI NEVLK+VVAKFNA QLIT                                                    QRAQF V +AKQE++QKIV AEGEA+AA ++G+AL+++ GY+KLRKI+AA+ I++T++TSQN+ YL A+ L+LNL ++SF    + + K K
Sbjct:    2 SPTGSKDLQMVNISLRVLSRPNAQELPSMYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLIT----------------------------------------------------QRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLGEALSKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRGSDSLIKGK 156

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BLAST of prohibitin-1 vs. Ensembl Mouse
Match: Phb2 (prohibitin 2 [Source:MGI Symbol;Acc:MGI:102520])

HSP 1 Score: 154.836 bits (390), Expect = 7.160e-47
Identity = 72/97 (74.23%), Postives = 84/97 (86.60%), Query Frame = 1

Query:  226 AEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVS 516
            AEGLH RIP  QYPII+D+R+RPR ISSPTGSKDLQMVNISLRVLSRP+  ++P +Y+ +G DY+E+VLPSI NEVLK+VVAKFNA QLITQR Q S
Sbjct:    2 AEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSMYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQFS 98

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BLAST of prohibitin-1 vs. UniProt/SwissProt
Match: sp|A9UMS3|PHB2_XENTR (Prohibitin-2 OS=Xenopus tropicalis OX=8364 GN=phb2 PE=2 SV=1)

HSP 1 Score: 350.903 bits (899), Expect = 4.823e-120
Identity = 166/259 (64.09%), Postives = 220/259 (84.94%), Query Frame = 1

Query:  142 MSKSFYTVDGGQRSIIFSRFGGIKEN-IYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFNESVEHI 915
            + +S +TV+GG R+I F+R GG++++ I AEGLH R P  QYPII+D+R+RPR ISSPTGSKDLQMVNI+LRVLSRP  +++P +Y+ +G DYDE+VLPSI NEVLK+VVAKFNA QLITQR QVSLLIR+ L ERAKDF+II+DDV+IT+LSFSR+Y+ AVE KQ++QQEAQRAQF V +AKQ+++QKIV AEGEA AA +IGDAL+++ GYLKLR+I+AA+ IA+T+++SQN+ YLNA++L+LNL + +F    + +
Sbjct:   36 VKESVFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRFPWFQYPIIYDIRARPRKISSPTGSKDLQMVNITLRVLSRPLASELPFMYQRLGLDYDERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSIILDDVAITELSFSREYTAAVESKQVAQQEAQRAQFLVEKAKQDQKQKIVQAEGEAAAAKMIGDALSKNPGYLKLRRIRAAQSIAKTIASSQNRVYLNADSLVLNLQDDTFTRGSDSL 294

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BLAST of prohibitin-1 vs. UniProt/SwissProt
Match: sp|Q2HJ97|PHB2_BOVIN (Prohibitin-2 OS=Bos taurus OX=9913 GN=PHB2 PE=2 SV=1)

HSP 1 Score: 350.517 bits (898), Expect = 5.481e-120
Identity = 167/261 (63.98%), Postives = 222/261 (85.06%), Query Frame = 1

Query:  148 KSFYTVDGGQRSIIFSRFGGIKEN-IYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFNESVEHIGKRK 927
            +S +TV+GG R+I F+R GG++++ I AEGLH RIP  QYPII+D+R+RPR ISSPTGSKDLQMVNISLRVLSRP+  ++P +Y+ +G DY+E+VLPSI NEVLK+VVAKFNA QLITQR QVSLLIR+ L ERAKDF++I+DDV+IT+LSFSR+Y+ AVE KQ++QQEAQRAQF V +AKQE++QKIV AEGEA+AA ++G+AL+++ GY+KLRKI+AA+ I++T++TSQN+ YL A+ L+LNL ++SF    + + K K
Sbjct:   38 ESVFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAMELPSMYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILDDVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAARMLGEALSKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRGSDSLIKGK 298

[Close]

BLAST of prohibitin-1 vs. UniProt/SwissProt
Match: sp|Q5XIH7|PHB2_RAT (Prohibitin-2 OS=Rattus norvegicus OX=10116 GN=Phb2 PE=1 SV=1)

HSP 1 Score: 350.517 bits (898), Expect = 5.852e-120
Identity = 167/261 (63.98%), Postives = 222/261 (85.06%), Query Frame = 1

Query:  148 KSFYTVDGGQRSIIFSRFGGIKEN-IYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFNESVEHIGKRK 927
            +S +TV+GG R+I F+R GG++++ I AEGLH RIP  QYPII+D+R+RPR ISSPTGSKDLQMVNISLRVLSRP+  ++P +Y+ +G DY+E+VLPSI NEVLK+VVAKFNA QLITQR QVSLLIR+ L ERAKDF++I+DDV+IT+LSFSR+Y+ AVE KQ++QQEAQRAQF V +AKQE++QKIV AEGEA+AA ++G+AL+++ GY+KLRKI+AA+ I++T++TSQN+ YL A+ L+LNL ++SF    + + K K
Sbjct:   38 ESVFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSMYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILDDVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLGEALSKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRGSDSLIKGK 298

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BLAST of prohibitin-1 vs. UniProt/SwissProt
Match: sp|O35129|PHB2_MOUSE (Prohibitin-2 OS=Mus musculus OX=10090 GN=Phb2 PE=1 SV=1)

HSP 1 Score: 350.132 bits (897), Expect = 7.202e-120
Identity = 167/261 (63.98%), Postives = 222/261 (85.06%), Query Frame = 1

Query:  148 KSFYTVDGGQRSIIFSRFGGIKEN-IYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFNESVEHIGKRK 927
            +S +TV+GG R+I F+R GG++++ I AEGLH RIP  QYPII+D+R+RPR ISSPTGSKDLQMVNISLRVLSRP+  ++P +Y+ +G DY+E+VLPSI NEVLK+VVAKFNA QLITQR QVSLLIR+ L ERAKDF++I+DDV+IT+LSFSR+Y+ AVE KQ++QQEAQRAQF V +AKQE++QKIV AEGEA+AA ++G+AL+++ GY+KLRKI+AA+ I++T++TSQN+ YL A+ L+LNL ++SF    + + K K
Sbjct:   38 ESVFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSMYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILDDVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLGEALSKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRGSDSLIKGK 298

[Close]

BLAST of prohibitin-1 vs. UniProt/SwissProt
Match: sp|Q99623|PHB2_HUMAN (Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2)

HSP 1 Score: 350.132 bits (897), Expect = 7.202e-120
Identity = 167/261 (63.98%), Postives = 222/261 (85.06%), Query Frame = 1

Query:  148 KSFYTVDGGQRSIIFSRFGGIKEN-IYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFNESVEHIGKRK 927
            +S +TV+GG R+I F+R GG++++ I AEGLH RIP  QYPII+D+R+RPR ISSPTGSKDLQMVNISLRVLSRP+  ++P +Y+ +G DY+E+VLPSI NEVLK+VVAKFNA QLITQR QVSLLIR+ L ERAKDF++I+DDV+IT+LSFSR+Y+ AVE KQ++QQEAQRAQF V +AKQE++QKIV AEGEA+AA ++G+AL+++ GY+KLRKI+AA+ I++T++TSQN+ YL A+ L+LNL ++SF    + + K K
Sbjct:   38 ESVFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSMYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILDDVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLGEALSKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRGSDSLIKGK 298

[Close]

BLAST of prohibitin-1 vs. TrEMBL
Match: I1ZIH0 (Prohibitin OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 559.681 bits (1441), Expect = 0.000e+0
Identity = 290/291 (99.66%), Postives = 291/291 (100.00%), Query Frame = 1

Query:   58 MDQNINISKFIKSPATRXXXXXXXXXXXMSKSFYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFNESVEHIGKRKN 930
            MDQNINISKFIKSPATRLLILGGGLLYGMSKSFYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERA+DFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFNESVEHIGKRKN
Sbjct:    1 MDQNINISKFIKSPATRLLILGGGLLYGMSKSFYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAQDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFNESVEHIGKRKN 291

[Close]

BLAST of prohibitin-1 vs. TrEMBL
Match: A0A0A7AD70 (Prohibitin OS=Dugesia japonica OX=6161 GN=Phb2 PE=2 SV=1)

HSP 1 Score: 488.034 bits (1255), Expect = 7.475e-172
Identity = 236/262 (90.08%), Postives = 255/262 (97.33%), Query Frame = 1

Query:  142 MSKSFYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFNESVEHIGKRK 927
            ++K+FYTVDGGQRSIIFSRFGGIKENIYAEGLH RIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPD+ KIPDIYRN+GEDYDE+VLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFS+QY EAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAA+LIGDAL+ +SGYLKLRKIKA+EKIARTLST+QN+AYLNANTLM+N+NEK FN+SV+ + K+K
Sbjct:   32 LTKAFYTVDGGQRSIIFSRFGGIKENIYAEGLHFRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDILKIPDIYRNLGEDYDERVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSKQYGEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAILIGDALSANSGYLKLRKIKASEKIARTLSTAQNRAYLNANTLMMNINEKEFNDSVDRVVKKK 293

[Close]

BLAST of prohibitin-1 vs. TrEMBL
Match: A0A5S6Q8Q8 (Uncharacterized protein OS=Trichuris muris OX=70415 PE=4 SV=1)

HSP 1 Score: 388.652 bits (997), Expect = 1.828e-132
Identity = 184/262 (70.23%), Postives = 222/262 (84.73%), Query Frame = 1

Query:  142 MSKSFYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFNESVEHIGKRK 927
            +S+SFYTVDGGQR+II+SR  G++  IY EGLH RIP  QYPI++DVR+RP  ISSPTGSKDLQMVNISLRVLSRPD   +P IYR +G D+DE+VLPSI NEVLK+VVAKFNA QLITQR+QVSLLIRK+L+ERAKDFNII+DDVSIT+LSF R+Y++AVE KQ++ QEAQRA F V RAKQERQQKIV AEGEAQAA ++G+A+ +  GYLKLRKI+AA+ IARTL+ S N+AYLNAN LMLN+  + F +S + I K+K
Sbjct:   36 LSQSFYTVDGGQRAIIYSRISGVRPEIYPEGLHFRIPWFQYPIVYDVRARPHKISSPTGSKDLQMVNISLRVLSRPDAPFLPRIYRTLGTDWDERVLPSICNEVLKSVVAKFNASQLITQRQQVSLLIRKMLVERAKDFNIILDDVSITELSFGREYAQAVEAKQVAAQEAQRAAFYVERAKQERQQKIVQAEGEAQAAKMLGEAMAKDPGYLKLRKIRAAQSIARTLAQSSNRAYLNANNLMLNIGSEEFLQSADEIFKKK 297

[Close]

BLAST of prohibitin-1 vs. TrEMBL
Match: A0A1D1VV90 (Prohibitin OS=Ramazzottius varieornatus OX=947166 GN=RvY_15538-1 PE=3 SV=1)

HSP 1 Score: 388.652 bits (997), Expect = 1.852e-132
Identity = 183/263 (69.58%), Postives = 226/263 (85.93%), Query Frame = 1

Query:  142 MSKSFYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFNESVEH-IGKRK 927
            +S+S YTV+GG R+IIFSR GG++  +YAEGLH RIP +QYPII+D+RSRPR ISSPTGSKDLQMVNISLRVL+RPD A +P +YR +G DYDE+VLPSI NEVLK+VVAKFNA QLITQR QVSLL+RK L +RA DFNII+DDV+ITDLSF ++Y+ +VE KQ++QQEAQRAQF V +AKQERQQKIV AEGEAQAA+L+GDA+++S GYLKLRKI+AA+ IART+S SQN+AYL+AN+LMLN+ +  +++     IGK K
Sbjct:   38 VSQSMYTVEGGHRAIIFSRIGGVQNEVYAEGLHFRIPWLQYPIIYDIRSRPRSISSPTGSKDLQMVNISLRVLARPDQATLPRLYRQLGTDYDERVLPSICNEVLKSVVAKFNAAQLITQRSQVSLLVRKELTQRAMDFNIILDDVAITDLSFGKEYTASVESKQVAQQEAQRAQFLVEKAKQERQQKIVQAEGEAQAALLLGDAVSKSPGYLKLRKIRAAQSIARTISQSQNRAYLDANSLMLNITDVEYDQGTRSIIGKNK 300

[Close]

BLAST of prohibitin-1 vs. TrEMBL
Match: A0A3P7LBU4 (Prohibitin OS=Dibothriocephalus latus OX=60516 GN=DILT_LOCUS10045 PE=3 SV=1)

HSP 1 Score: 385.185 bits (988), Expect = 2.604e-131
Identity = 183/262 (69.85%), Postives = 224/262 (85.50%), Query Frame = 1

Query:  142 MSKSFYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFNESVEHIGKRK 927
            + +S +TVDGG R I+FSR GG+K +IY EGLHLRIP  QYPII+D+RSRP  I+SPTGSKDLQ +N++LRVLSRP+++K+P+IYR +G DYD++VLPSI NEVLKAVVAKFNA QLITQR+QVSLLIRK L++RA+DF I+VDDVSITDL+FS+ Y+ AVE KQI+QQEAQRAQF V RAKQERQQKIV A+GEAQAA LIGDAL  + GYLKLRKIKAA +IARTLS S N+ +LNANTL++NL++  F+ S E + K+K
Sbjct:   28 IQQSLFTVDGGHRGIMFSRIGGVKPDIYPEGLHLRIPWFQYPIIYDIRSRPHKITSPTGSKDLQTINLTLRVLSRPEVSKLPEIYRTLGTDYDDRVLPSIVNEVLKAVVAKFNASQLITQRQQVSLLIRKQLVDRARDFYIVVDDVSITDLTFSQVYASAVESKQIAQQEAQRAQFLVERAKQERQQKIVMADGEAQAAKLIGDALQANPGYLKLRKIKAAAQIARTLSQSSNRVFLNANTLLMNLSDPQFDASCEKVIKKK 289

[Close]

BLAST of prohibitin-1 vs. Ensembl Cavefish
Match: phb2a (prohibitin-2-like [Source:NCBI gene;Acc:103035142])

HSP 1 Score: 355.91 bits (912), Expect = 6.095e-123
Identity = 169/253 (66.80%), Postives = 222/253 (87.75%), Query Frame = 1

Query:  142 MSKSFYTVDGGQRSIIFSRFGGI-KENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFN 897
            + ++ YTV+GGQR+IIF+R GG+ K+ + AEGLH RIP  QYPII+D+R+RPR ISS TGSKDLQMVNI+LRVLSRP  + +P +Y+++G DYDE+VLPSI NEVLK+VVAKFNA QLITQR QVS+LIR+ LIERAKDFNII+DDV+IT+LSFSR+Y+ AVE KQ++QQEAQRAQF V +AKQ+++QKI+ AEGEA+AA L+G+A+T++ GYLKLR+I+AA+ IA+T+++SQNK YLNA++L++NL + SFN
Sbjct:   44 VKEAMYTVEGGQRAIIFNRIGGMEKDTVLAEGLHFRIPWFQYPIIYDIRARPRKISSLTGSKDLQMVNIALRVLSRPVASNLPFLYQHLGVDYDERVLPSIVNEVLKSVVAKFNASQLITQRAQVSMLIRRELIERAKDFNIILDDVAITELSFSREYTAAVEAKQVAQQEAQRAQFYVEKAKQDQRQKIIQAEGEAEAAKLLGEAVTKNPGYLKLRRIRAAQNIAKTVASSQNKLYLNADSLVMNLQDSSFN 296

[Close]

BLAST of prohibitin-1 vs. Ensembl Cavefish
Match: phb2b (prohibitin-2-like [Source:NCBI gene;Acc:103047478])

HSP 1 Score: 351.288 bits (900), Expect = 3.957e-121
Identity = 164/248 (66.13%), Postives = 218/248 (87.90%), Query Frame = 1

Query:  157 YTVDGGQRSIIFSRFGGIK-ENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFN 897
            YTV+GGQR+I+F+R GG++ + + +EGLH RIP  QYPII+D+R++PR ISS TGSKDLQMVNI+LRVLSRP  + +P +Y+++G+DYDE+VLPSI NEVLK+VVAKFNA QL+TQR QVSLLIR+ L ERAKDFNII+DDV+IT+LSFSR+Y+ AVE KQ++QQEAQRAQF V +AKQE++QKI+ AEGEA+AA ++G+A+T++ GYLKLR+I+AA+ IA+T++ SQNK YLNA++L++NL + SFN
Sbjct:   49 YTVEGGQRAIVFNRVGGMQMDTVLSEGLHFRIPWFQYPIIYDIRAKPRKISSLTGSKDLQMVNIALRVLSRPVASNLPYMYQHLGKDYDERVLPSIVNEVLKSVVAKFNASQLLTQRAQVSLLIRRELFERAKDFNIILDDVAITELSFSREYTAAVEAKQVAQQEAQRAQFFVEKAKQEQKQKIIQAEGEAEAAKMLGEAVTKNPGYLKLRRIRAAQNIAKTVAASQNKVYLNADSLVMNLQDDSFN 296

[Close]

BLAST of prohibitin-1 vs. Ensembl Cavefish
Match: phb2b (prohibitin-2-like [Source:NCBI gene;Acc:103047478])

HSP 1 Score: 332.028 bits (850), Expect = 8.043e-114
Identity = 159/254 (62.60%), Postives = 212/254 (83.46%), Query Frame = 1

Query:  157 YTVDGGQRSIIFSRFGGIK-ENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLST-----SQNKAYLNANTLMLNLNEKSFNE 900
            YTV+GGQR+I+F+R GG++ + + +EGLH RIP  QYPII+D+R++PR ISS TGSKDLQMVNI+LRVLSRP  + +P +Y+++G+DYDE+VLPSI NEVLK+VVAKFNA QL+TQR QVSLLIR+ L ERAKDFNII+DDV+IT+LSFSR+Y+ AVE KQ++QQEAQRAQF V +AKQE++QKI+ AEGEA+AA ++G+A+T++ GYLKLR+I+A   +    S       +NK YLNA++L++NL + SFN+
Sbjct:   30 YTVEGGQRAIVFNRVGGMQMDTVLSEGLHFRIPWFQYPIIYDIRAKPRKISSLTGSKDLQMVNIALRVLSRPVASNLPYMYQHLGKDYDERVLPSIVNEVLKSVVAKFNASQLLTQRAQVSLLIRRELFERAKDFNIILDDVAITELSFSREYTAAVEAKQVAQQEAQRAQFFVEKAKQEQKQKIIQAEGEAEAAKMLGEAVTKNPGYLKLRRIRAVFLLTVVCSCFLSKNRKNKVYLNADSLVMNLQDDSFNK 283

[Close]

BLAST of prohibitin-1 vs. Ensembl Cavefish
Match: phb2a (prohibitin-2-like [Source:NCBI gene;Acc:103035142])

HSP 1 Score: 330.872 bits (847), Expect = 1.547e-112
Identity = 160/247 (64.78%), Postives = 209/247 (84.62%), Query Frame = 1

Query:  142 MSKSFYTVDGGQRSIIFSRFGGI-KENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNL 879
            + ++ YTV+GGQR+IIF+R GG+ K+ + AEGLH RIP  QYPII+D+R+RPR ISS TGSKDLQMVNI+LRVLSRP  + +P +Y+++G DYDE+VLPSI NEVLK+VVAKFNA QLITQR QVS+LIR+ LIERAKDFNII+DDV+IT+LSFSR+Y+ AVE KQ++QQEAQRAQF V +AKQ+++QKI+ AEGEA+AA L+G+A+T++ GYLKLR+I+AA+ IA+T+S   +  Y N N  + +L
Sbjct:   44 VKEAMYTVEGGQRAIIFNRIGGMEKDTVLAEGLHFRIPWFQYPIIYDIRARPRKISSLTGSKDLQMVNIALRVLSRPVASNLPFLYQHLGVDYDERVLPSIVNEVLKSVVAKFNASQLITQRAQVSMLIRRELIERAKDFNIILDDVAITELSFSREYTAAVEAKQVAQQEAQRAQFYVEKAKQDQRQKIIQAEGEAEAAKLLGEAVTKNPGYLKLRRIRAAQNIAKTVSLLLSYPYKNFNCKIWSL 290

[Close]

BLAST of prohibitin-1 vs. Ensembl Cavefish
Match: phb (prohibitin [Source:NCBI gene;Acc:103031128])

HSP 1 Score: 265.774 bits (678), Expect = 4.667e-88
Identity = 128/238 (53.78%), Postives = 181/238 (76.05%), Query Frame = 1

Query:  142 MSKSFYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSS-GYLKLRKIKAAEKIARTLSTSQNKAYL 852
            ++ + + VD G R++IF RF G+++ +  EG H  IP +Q PIIFD RSRPR +   TGSKDLQ VNI+LR+L RP   ++P I+ +IGEDYDE+VLPSI+ EVLKAVVA+F+AG+LITQRE VS  + + L ERA  F +I+DDVS+T L+F ++++EAVE KQ++QQEA+RA+F V +A+Q++Q  I++A G++QAA+LI D+L  +  G ++LRK++AAE IA  LS S+N  YL
Sbjct:   22 VNSALFNVDAGHRAVIFDRFRGVQDAVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVVTGSKDLQNVNITLRILFRPVANQLPRIFTSIGEDYDERVLPSITTEVLKAVVARFDAGELITQRELVSRQVSEDLTERASTFGLILDDVSLTHLTFGKEFTEAVEMKQVAQQEAERARFVVEKAEQQKQAAIISAAGDSQAALLIADSLAVAGDGLVELRKLEAAEDIAFQLSRSRNVTYL 259

[Close]

BLAST of prohibitin-1 vs. Ensembl Sea Lamprey
Match: phb (prohibitin [Source:ZFIN;Acc:ZDB-GENE-030131-6577])

HSP 1 Score: 269.24 bits (687), Expect = 4.701e-90
Identity = 132/243 (54.32%), Postives = 187/243 (76.95%), Query Frame = 1

Query:  151 SFYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSS-GYLKLRKIKAAEKIARTLSTSQNKAYLNA--NTLM 870
            +F TV+GG R++IF RF G+++ +  EG H  IP +Q PIIFD RSRPR +   TGSKD+Q VNI+LR+L RP  +++P IY +IGEDYDE+VLPSI+ EVLKAVVA+F+AG+LITQRE VS  +   L+ERA  F +I+DDVS+T L+F R++++AVE KQ++QQEA+RA+F V RA+Q+++  I+ AEG+A+AA LI  A++++  G ++LRK++AAE IA  LS S+  AYL +  +TL+
Sbjct:   24 AFLTVEGGHRAVIFDRFRGVQDLVVGEGTHFVIPWVQRPIIFDCRSRPRNVPVVTGSKDMQNVNITLRILFRPIASQLPKIYMSIGEDYDERVLPSITTEVLKAVVARFDAGELITQRELVSRQVSNDLMERAATFGLILDDVSLTHLTFGREFTQAVEAKQVAQQEAERARFVVERAEQQKKAAIIAAEGDAKAAQLIATAISEAGEGLVELRKLEAAEDIAMQLSKSRGVAYLPSGQHTLL 266

[Close]

BLAST of prohibitin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006512.1 (pep scaffold:Pmarinus_7.0:GL479067:257:4164:-1 gene:ENSPMAG00000005886.1 transcript:ENSPMAT00000006512.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 189.889 bits (481), Expect = 1.633e-60
Identity = 89/120 (74.17%), Postives = 104/120 (86.67%), Query Frame = 1

Query:  157 YTVDGGQRSIIFSRFGGIKEN-IYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQV 513
            YTVDGGQR+IIFSR GGI+EN I AEGLH RIP   YPII+D+R++PR ISSPTGSKDLQMVNI+LRVLSRPD  K+P +++ +G DY+E+VLPSI NEVLK+VVAKFNA QLITQR QV
Sbjct:   41 YTVDGGQRAIIFSRLGGIQENTILAEGLHFRIPWFHYPIIYDIRAKPRKISSPTGSKDLQMVNITLRVLSRPDALKLPRMFQQLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQV 160

[Close]

BLAST of prohibitin-1 vs. Ensembl Yeast
Match: PHB2 (Subunit of the prohibitin complex (Phb1p-Phb2p); prohibitin is a 1.2 MDa ring-shaped inner mitochondrial membrane chaperone that stabilizes newly synthesized proteins; determinant of replicative life span; involved in mitochondrial segregation; prohibitin deficiency induces a mitochondrial unfolded protein response (mtUPR) [Source:SGD;Acc:S000003463])

HSP 1 Score: 284.263 bits (726), Expect = 1.391e-95
Identity = 133/245 (54.29%), Postives = 190/245 (77.55%), Query Frame = 1

Query:  142 MSKSFYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLN 876
            ++ + + VDGG R+I++SR  G+   I+ EG H   P +  PII+DVR++PR ++S TG+KDLQMVNI+ RVLSRPD+ ++P IYR +G+DYDE+VLPSI NEVLKAVVA+FNA QLITQRE+VS LIR+ L+ RA  FNI++DDVSIT ++FS +++ AVE KQI+QQ+AQRA F V +A+QE+Q  +V A+GEA++A LIG+A+ +S  Y++L+++  A  IA+ L++S N+  L+   L+LN
Sbjct:   54 INNALFNVDGGHRAIVYSRIHGVSSRIFNEGTHFIFPWLDTPIIYDVRAKPRNVASLTGTKDLQMVNITCRVLSRPDVVQLPTIYRTLGQDYDERVLPSIVNEVLKAVVAQFNASQLITQREKVSRLIRENLVRRASKFNILLDDVSITYMTFSPEFTNAVEAKQIAQQDAQRAAFVVDKARQEKQGMVVRAQGEAKSAELIGEAIKKSRDYVELKRLDTARDIAKILASSPNRVILDNEALLLN 298

[Close]

BLAST of prohibitin-1 vs. Ensembl Yeast
Match: PHB1 (Subunit of the prohibitin complex (Phb1p-Phb2p); prohibitin is a 1.2 MDa ring-shaped inner mitochondrial membrane chaperone that stabilizes newly synthesized proteins; determinant of replicative life span; involved in mitochondrial segregation; prohibitin deficiency induces a mitochondrial unfolded protein response (mtUPR) [Source:SGD;Acc:S000003364])

HSP 1 Score: 253.447 bits (646), Expect = 8.498e-84
Identity = 124/259 (47.88%), Postives = 186/259 (71.81%), Query Frame = 1

Query:  151 SFYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQ-SSGYLKLRKIKAAEKIARTLSTSQNKAYLNA--------------NTLMLNLN 882
            S Y V GG R +IF R  G+K+ +  EG H  +P +Q  II+DVR++P+ I++ TG+KDLQMV+++LRVL RP++ ++P IY+N+G DYDE+VLPSI NEVLK++VA+F+A +LITQRE +S  IRK L  RA +F I ++DVSIT ++F  ++++AVE+KQI+QQ+A+RA+F V +A+QERQ  ++ AEGEA++A  I  AL +   G L +R+++A++ IA+TL+ S N  YL +              N+L+LN+ 
Sbjct:   28 SMYDVKGGSRGVIFDRINGVKQQVVGEGTHFLVPWLQKAIIYDVRTKPKSIATNTGTKDLQMVSLTLRVLHRPEVLQLPAIYQNLGLDYDERVLPSIGNEVLKSIVAQFDAAELITQREIISQKIRKELSTRANEFGIKLEDVSITHMTFGPEFTKAVEQKQIAQQDAERAKFLVEKAEQERQASVIRAEGEAESAEFISKALAKVGDGLLLIRRLEASKDIAQTLANSSNVVYLPSQHSGGGNSESSGSPNSLLLNIG 286

[Close]

BLAST of prohibitin-1 vs. Ensembl Nematostella
Match: EDO42348 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1L7])

HSP 1 Score: 352.829 bits (904), Expect = 2.440e-122
Identity = 167/262 (63.74%), Postives = 213/262 (81.30%), Query Frame = 1

Query:  142 MSKSFYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFNESVEHIGKRK 927
            + +S YTVDGG R+IIFSR GG+++ +Y EGLH RIP  QYPII+D+RSRPR I SPTGSKDLQMVNI LRVL+RP+  K+P +YR +G D+DE+VLPSI NEVLK+VVA+FNA QLIT R+QVSLLIR+ L+ERA+DF II+DDVSITDLSF ++Y+ A+E KQ++QQEAQRAQF V +A QERQQKIV AEGEAQAA L+G+AL  + GYL+LRKI+AA+KI+R ++ SQN  YL+++ L+LNL      +   ++ K K
Sbjct:   36 IKESVYTVDGGHRAIIFSRIGGVQDTVYTEGLHFRIPWFQYPIIYDIRSRPRKIISPTGSKDLQMVNIGLRVLARPEANKLPPMYRKLGLDFDERVLPSIMNEVLKSVVAQFNASQLITMRQQVSLLIRRQLMERARDFYIILDDVSITDLSFGKEYTSAIEAKQVAQQEAQRAQFIVEKAIQERQQKIVQAEGEAQAAKLLGEALKDNPGYLRLRKIRAAQKISRVIAASQNPVYLDSDGLLLNLRHADVIDDTSYLKKEK 297

[Close]

BLAST of prohibitin-1 vs. Ensembl Nematostella
Match: EDO49486 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG85])

HSP 1 Score: 270.781 bits (691), Expect = 2.294e-90
Identity = 127/247 (51.42%), Postives = 187/247 (75.71%), Query Frame = 1

Query:  145 SKSFYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSS-GYLKLRKIKAAEKIARTLSTSQNKAYL-NANTLMLNL 879
            + + + VDGG R++IF RF G+K ++  EG H  IP +Q PIIFD+R+RPR +   TGSKDLQ VNI+LR+L RP    +P IY N+GEDYDE+VLPSI+ EVLKAVVA+F+AG+LITQRE VS  +++ L ERA  F +++DD+S+T L+F ++++EAVE KQ++QQ+A+RA+F V RA+Q+++  +++AEG+A+ A L+  A  ++  G ++LRKI+A+E+IA  +S S+N AYL     ++LNL
Sbjct:   24 NSALFNVDGGHRAVIFDRFQGVKPDVVGEGTHFLIPWVQRPIIFDIRTRPRNVPVTTGSKDLQNVNITLRILYRPQPQVLPKIYMNLGEDYDERVLPSITTEVLKAVVAQFDAGELITQREMVSQKVQEDLTERASSFGLVLDDISLTHLTFGKEFTEAVELKQVAQQDAERARFLVERAEQQKKAAVISAEGDARGAALLAQAFKEAGEGLVELRKIEASEEIAERMSRSRNVAYLPGGQKMLLNL 270

[Close]

BLAST of prohibitin-1 vs. Ensembl Medaka
Match: phb2b (prohibitin 2 [Source:NCBI gene;Acc:101159337])

HSP 1 Score: 342.043 bits (876), Expect = 1.434e-117
Identity = 163/257 (63.42%), Postives = 219/257 (85.21%), Query Frame = 1

Query:  157 YTVDGGQRSIIFSRFGGIK-ENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFNESVEHIGKR 924
            YTV+GG R+I+F+R GG++ + I +EGLH RIP IQYPII+D+R++PR ISS TGSKDLQMVNI++RVLSRP  + +P +Y+ +G+DYDE+VLPSI NEVLK+VVAKFNA QLITQR QVSLL+R+ L +RAKDFNII+DDVSIT+LSFS QY+ AVE KQ++QQEAQRAQF V +AKQ+++QKI+ AEGEA+AA ++G A+T++ GYLKLR+I+AA+ IA+T++ SQN+ YLNA+ L+LNL ++SF  ++  + K+
Sbjct:   49 YTVEGGHRAIVFNRIGGMQMDTILSEGLHFRIPWIQYPIIYDIRAKPRKISSLTGSKDLQMVNIAVRVLSRPLASNLPIMYQQLGKDYDERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLVRRELYDRAKDFNIILDDVSITELSFSSQYTAAVEAKQVAQQEAQRAQFYVEKAKQDQRQKIIQAEGEAEAAKMLGQAVTKNPGYLKLRRIRAAQNIAKTVAASQNRIYLNADGLVLNLQDQSFFNTLSLMQKK 305

[Close]

BLAST of prohibitin-1 vs. Ensembl Medaka
Match: phb (prohibitin [Source:NCBI gene;Acc:101158276])

HSP 1 Score: 266.544 bits (680), Expect = 2.781e-88
Identity = 127/238 (53.36%), Postives = 183/238 (76.89%), Query Frame = 1

Query:  142 MSKSFYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSS-GYLKLRKIKAAEKIARTLSTSQNKAYL 852
            ++ + Y VD G R++IF RF G+++ +  EG H  IP +Q P+IFD RSRPR +   TGSKDLQ VNI+LR+L RP  +++P I+ +IGEDYDE+VLPSI+ EVLKAVVA+F+AG+LITQRE VS  + + L ERA  F +I+DDVS+T L+F ++++EAVE KQ++QQEA+RA+F V +A+Q++Q  I++AEG++QAA+LI ++L  +  G ++LRK++AAE IA  L+ S+N  YL
Sbjct:   22 VNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPWVQKPVIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVTSQLPRIFTSIGEDYDERVLPSITTEVLKAVVARFDAGELITQRELVSRQVSEDLTERATTFGLILDDVSLTHLTFGKEFTEAVEMKQVAQQEAERARFVVEKAEQQKQATIISAEGDSQAALLIANSLMDAGDGLVELRKLEAAEDIAFQLARSRNVTYL 259

[Close]

BLAST of prohibitin-1 vs. Ensembl Medaka
Match: phb (prohibitin [Source:NCBI gene;Acc:101158276])

HSP 1 Score: 266.159 bits (679), Expect = 8.291e-88
Identity = 127/238 (53.36%), Postives = 183/238 (76.89%), Query Frame = 1

Query:  142 MSKSFYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSS-GYLKLRKIKAAEKIARTLSTSQNKAYL 852
            ++ + Y VD G R++IF RF G+++ +  EG H  IP +Q P+IFD RSRPR +   TGSKDLQ VNI+LR+L RP  +++P I+ +IGEDYDE+VLPSI+ EVLKAVVA+F+AG+LITQRE VS  + + L ERA  F +I+DDVS+T L+F ++++EAVE KQ++QQEA+RA+F V +A+Q++Q  I++AEG++QAA+LI ++L  +  G ++LRK++AAE IA  L+ S+N  YL
Sbjct:   50 VNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPWVQKPVIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVTSQLPRIFTSIGEDYDERVLPSITTEVLKAVVARFDAGELITQRELVSRQVSEDLTERATTFGLILDDVSLTHLTFGKEFTEAVEMKQVAQQEAERARFVVEKAEQQKQATIISAEGDSQAALLIANSLMDAGDGLVELRKLEAAEDIAFQLARSRNVTYL 287

[Close]

BLAST of prohibitin-1 vs. Planmine SMEST
Match: SMESG000021272.1 (SMESG000021272.1)

HSP 1 Score: 559.681 bits (1441), Expect = 0.000e+0
Identity = 290/291 (99.66%), Postives = 291/291 (100.00%), Query Frame = 1

Query:   58 MDQNINISKFIKSPATRXXXXXXXXXXXMSKSFYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFNESVEHIGKRKN 930
            MDQNINISKFIKSPATRLLILGGGLLYGMSKSFYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERA+DFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFNESVEHIGKRKN
Sbjct:    1 MDQNINISKFIKSPATRLLILGGGLLYGMSKSFYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAQDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFNESVEHIGKRKN 291

[Close]

BLAST of prohibitin-1 vs. Planmine SMEST
Match: SMESG000021272.1 (SMESG000021272.1)

HSP 1 Score: 530.02 bits (1364), Expect = 0.000e+0
Identity = 262/263 (99.62%), Postives = 263/263 (100.00%), Query Frame = 1

Query:  142 MSKSFYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFNESVEHIGKRKN 930
            MSKSFYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERA+DFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFNESVEHIGKRKN
Sbjct:    1 MSKSFYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAQDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAEKIARTLSTSQNKAYLNANTLMLNLNEKSFNESVEHIGKRKN 263

[Close]

BLAST of prohibitin-1 vs. Planmine SMEST
Match: SMESG000038397.1 (SMESG000038397.1)

HSP 1 Score: 247.669 bits (631), Expect = 4.215e-81
Identity = 116/234 (49.57%), Postives = 173/234 (73.93%), Query Frame = 1

Query:  154 FYTVDGGQRSIIFSRFGGIKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRVLSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSS-GYLKLRKIKAAEKIARTLSTSQNKAYL 852
             YTV GG R++IF R  G++ ++  EG H  IP IQ PII+D+R+RPR +   TGSKDLQ VNI+LR+L +P    +P IY N+G D++E+VLPSI+ EVLK VVA+F+A  LITQRE VS  + ++L  RA +F +++DD+S+T L+F  ++S+AVE KQ++QQEA+RA+F V +A+QE+   I++AEG++QAA L+  +  Q   G+++L++I+ +E+IAR LS ++N  YL
Sbjct:   25 LYTVPGGHRAVIFDRISGVRPDVIGEGTHFLIPWIQKPIIYDIRTRPRNVPVNTGSKDLQKVNITLRILYKPKAEMLPKIYTNLGLDFEERVLPSITYEVLKTVVAQFDASDLITQRELVSNKVNEMLTSRASNFGLMLDDISLTHLTFGTEFSDAVELKQVAQQEAERARFLVEKAEQEKLAAIISAEGDSQAANLLAKSFNQCGEGFIELQRIQTSEEIARLLSKNKNIVYL 258

The following BLAST results are available for this feature:

BLAST of prohibitin-1 vs. Ensembl Human
BLAST of prohibitin-1 vs. Ensembl Celegans
BLAST of prohibitin-1 vs. Ensembl Fly
BLAST of prohibitin-1 vs. Ensembl Zebrafish
BLAST of prohibitin-1 vs. Ensembl Xenopus
BLAST of prohibitin-1 vs. Ensembl Mouse
BLAST of prohibitin-1 vs. UniProt/SwissProt
BLAST of prohibitin-1 vs. TrEMBL
BLAST of prohibitin-1 vs. Ensembl Cavefish
BLAST of prohibitin-1 vs. Ensembl Sea Lamprey
BLAST of prohibitin-1 vs. Ensembl Yeast
BLAST of prohibitin-1 vs. Ensembl Nematostella
BLAST of prohibitin-1 vs. Ensembl Medaka
BLAST of prohibitin-1 vs. Planmine SMEST

BLAST of prohibitin-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
PHB2	7.608e-121	64.37	prohibitin 2 [Source:HGNC Symbol;Acc:HGNC:30306]	[more]
PHB2	1.500e-120	63.98	prohibitin 2 [Source:HGNC Symbol;Acc:HGNC:30306]	[more]
PHB2	2.414e-109	67.26	prohibitin 2 [Source:HGNC Symbol;Acc:HGNC:30306]	[more]
PHB2	3.720e-93	54.02	prohibitin 2 [Source:HGNC Symbol;Acc:HGNC:30306]	[more]
PHB	5.870e-87	52.02	prohibitin [Source:HGNC Symbol;Acc:HGNC:8912]	[more]

BLAST of prohibitin-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3


Match Name	E-value	Identity	Description
phb-2	1.648e-113	62.65	Mitochondrial prohibitin complex protein 2 [Sourc...	[more]
phb-2	1.648e-113	62.65	Mitochondrial prohibitin complex protein 2 [Sourc...	[more]
phb-1	3.087e-80	51.84	Mitochondrial prohibitin complex protein 1 [Sourc...	[more]

BLAST of prohibitin-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Phb2	1.100e-129	66.67	gene:FBgn0010551 transcript:FBtr0086614	[more]
Phb2	1.100e-129	66.67	gene:FBgn0010551 transcript:FBtr0086615	[more]
Phb2	1.100e-129	66.67	gene:FBgn0010551 transcript:FBtr0086616	[more]
Phb2	1.100e-129	66.67	gene:FBgn0010551 transcript:FBtr0112863	[more]
Phb2	3.491e-129	66.80	gene:FBgn0010551 transcript:FBtr0112861	[more]

BLAST of prohibitin-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
phb2b	1.192e-121	67.07	prohibitin 2b [Source:ZFIN;Acc:ZDB-GENE-040718-430...	[more]
phb2b	1.192e-121	67.07	prohibitin 2b [Source:ZFIN;Acc:ZDB-GENE-040718-430...	[more]
phb2b	1.192e-121	67.07	prohibitin 2b [Source:ZFIN;Acc:ZDB-GENE-040718-430...	[more]
phb2a	1.167e-120	66.94	prohibitin 2a [Source:ZFIN;Acc:ZDB-GENE-030131-314...	[more]
phb	2.995e-88	53.36	prohibitin [Source:ZFIN;Acc:ZDB-GENE-030131-6577]	[more]

BLAST of prohibitin-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 4


Match Name	E-value	Identity	Description
cgref1	9.104e-121	64.09	cell growth regulator with EF-hand domain 1 [Sourc...	[more]
cgref1	1.239e-120	65.61	cell growth regulator with EF-hand domain 1 [Sourc...	[more]
cgref1	1.239e-120	65.61	cell growth regulator with EF-hand domain 1 [Sourc...	[more]
phb	3.387e-85	51.68	prohibitin [Source:NCBI gene;Acc:394635]	[more]

BLAST of prohibitin-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Phb2	1.030e-120	63.98	prohibitin 2 [Source:MGI Symbol;Acc:MGI:102520]	[more]
Phb	1.141e-87	52.42	prohibitin [Source:MGI Symbol;Acc:MGI:97572]	[more]
Phb	1.510e-71	55.14	prohibitin [Source:MGI Symbol;Acc:MGI:97572]	[more]
Phb2	1.140e-55	47.34	prohibitin 2 [Source:MGI Symbol;Acc:MGI:102520]	[more]
Phb2	7.160e-47	74.23	prohibitin 2 [Source:MGI Symbol;Acc:MGI:102520]	[more]

BLAST of prohibitin-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|A9UMS3\|PHB2_XENTR	4.823e-120	64.09	Prohibitin-2 OS=Xenopus tropicalis OX=8364 GN=phb2...	[more]
sp\|Q2HJ97\|PHB2_BOVIN	5.481e-120	63.98	Prohibitin-2 OS=Bos taurus OX=9913 GN=PHB2 PE=2 SV...	[more]
sp\|Q5XIH7\|PHB2_RAT	5.852e-120	63.98	Prohibitin-2 OS=Rattus norvegicus OX=10116 GN=Phb2...	[more]
sp\|O35129\|PHB2_MOUSE	7.202e-120	63.98	Prohibitin-2 OS=Mus musculus OX=10090 GN=Phb2 PE=1...	[more]
sp\|Q99623\|PHB2_HUMAN	7.202e-120	63.98	Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 ...	[more]

BLAST of prohibitin-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
I1ZIH0	0.000e+0	99.66	Prohibitin OS=Schmidtea mediterranea OX=79327 PE=2...	[more]
A0A0A7AD70	7.475e-172	90.08	Prohibitin OS=Dugesia japonica OX=6161 GN=Phb2 PE=...	[more]
A0A5S6Q8Q8	1.828e-132	70.23	Uncharacterized protein OS=Trichuris muris OX=7041...	[more]
A0A1D1VV90	1.852e-132	69.58	Prohibitin OS=Ramazzottius varieornatus OX=947166 ...	[more]
A0A3P7LBU4	2.604e-131	69.85	Prohibitin OS=Dibothriocephalus latus OX=60516 GN=...	[more]

BLAST of prohibitin-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
phb2a	6.095e-123	66.80	prohibitin-2-like [Source:NCBI gene;Acc:103035142]	[more]
phb2b	3.957e-121	66.13	prohibitin-2-like [Source:NCBI gene;Acc:103047478]	[more]
phb2b	8.043e-114	62.60	prohibitin-2-like [Source:NCBI gene;Acc:103047478]	[more]
phb2a	1.547e-112	64.78	prohibitin-2-like [Source:NCBI gene;Acc:103035142]	[more]
phb	4.667e-88	53.78	prohibitin [Source:NCBI gene;Acc:103031128]	[more]

BLAST of prohibitin-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
phb	4.701e-90	54.32	prohibitin [Source:ZFIN;Acc:ZDB-GENE-030131-6577]	[more]
ENSPMAT00000006512.1	1.633e-60	74.17	pep scaffold:Pmarinus_7.0:GL479067:257:4164:-1 gen...	[more]

BLAST of prohibitin-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2


Match Name	E-value	Identity	Description
PHB2	1.391e-95	54.29	Subunit of the prohibitin complex (Phb1p-Phb2p); p...	[more]
PHB1	8.498e-84	47.88	Subunit of the prohibitin complex (Phb1p-Phb2p); p...	[more]

BLAST of prohibitin-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2


Match Name	E-value	Identity	Description
EDO42348	2.440e-122	63.74	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49486	2.294e-90	51.42	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of prohibitin-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3


Match Name	E-value	Identity	Description
phb2b	1.434e-117	63.42	prohibitin 2 [Source:NCBI gene;Acc:101159337]	[more]
phb	2.781e-88	53.36	prohibitin [Source:NCBI gene;Acc:101158276]	[more]
phb	8.291e-88	53.36	prohibitin [Source:NCBI gene;Acc:101158276]	[more]

BLAST of prohibitin-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3


Match Name	E-value	Identity	Description
SMESG000021272.1	0.000e+0	99.66	SMESG000021272.1	[more]
SMESG000021272.1	0.000e+0	99.62	SMESG000021272.1	[more]
SMESG000038397.1	4.215e-81	49.57	SMESG000038397.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Cross References

External references for this transcript


Database	Accession
SmedGD GBrowse	SMED30020615
GenBank	AFJ24824.1

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30020615 ID=SMED30020615|Name=prohibitin-1|organism=Schmidtea mediterranea sexual|type=transcript|length=989bp
TTGTCTTGTGTTTTAATTAAGAAAACTTTTGAAAAAACCTGCGCACGCCA
TTAATAAATGGATCAAAATATTAATATATCAAAATTTATAAAAAGCCCTG
CTACACGCTTATTAATACTCGGAGGAGGTCTTTTATATGGCATGAGCAAA
TCTTTTTATACAGTTGATGGTGGCCAAAGGAGTATTATTTTCAGTAGATT
TGGGGGAATTAAAGAAAATATTTATGCTGAAGGACTTCATCTTAGAATTC
CTGGTATACAATATCCAATTATTTTTGATGTTAGATCCCGTCCTAGAATT
ATTTCTTCGCCAACTGGTAGTAAAGATTTGCAAATGGTGAATATTTCATT
AAGAGTATTAAGCAGACCAGATATGGCAAAAATTCCCGATATTTATCGAA
ATATTGGTGAAGACTATGATGAGAAAGTGTTACCGTCTATATCAAATGAG
GTTTTAAAAGCTGTTGTTGCAAAATTCAACGCTGGTCAGCTAATAACTCA
AAGAGAACAGGTGTCTTTGTTAATTCGAAAGCTTCTAATAGAAAGAGCTA
AAGATTTTAACATAATTGTTGATGACGTTTCGATTACGGATTTATCATTT
TCCAGACAATATAGCGAAGCAGTCGAACGAAAACAAATTTCACAACAAGA
AGCTCAAAGGGCTCAATTTACTGTAATGCGAGCTAAACAAGAACGACAGC
AGAAAATTGTCAACGCCGAAGGAGAGGCACAAGCTGCAGTTTTGATTGGA
GATGCTTTAACCCAGAGTTCCGGTTATTTGAAGCTACGTAAAATAAAGGC
TGCCGAAAAGATTGCGCGGACATTGTCGACTTCTCAAAATAAGGCTTATT
TGAATGCGAATACTCTGATGCTGAATTTGAACGAGAAGAGTTTCAACGAA
AGTGTGGAACACATAGGCAAACGTAAAAATTAAAAATTCACATAAAAATA
TTAGTTCGATTTAAATAAATTACAAACTGTGTTGTCTTG

protein sequence of SMED30020615-orf-1

>SMED30020615-orf-1 ID=SMED30020615-orf-1|Name=SMED30020615-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=292bp
MDQNINISKFIKSPATRLLILGGGLLYGMSKSFYTVDGGQRSIIFSRFGG
IKENIYAEGLHLRIPGIQYPIIFDVRSRPRIISSPTGSKDLQMVNISLRV
LSRPDMAKIPDIYRNIGEDYDEKVLPSISNEVLKAVVAKFNAGQLITQRE
QVSLLIRKLLIERAKDFNIIVDDVSITDLSFSRQYSEAVERKQISQQEAQ
RAQFTVMRAKQERQQKIVNAEGEAQAAVLIGDALTQSSGYLKLRKIKAAE
KIARTLSTSQNKAYLNANTLMLNLNEKSFNESVEHIGKRKN*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **cellular component**
Term	Definition
GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0016020	membrane

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000026	gut
PLANA:0000429	neoblast
PLANA:0002032	epidermal cell
PLANA:0002109	X1 cell
PLANA:0002111	X2 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036013	Band_7/SPFH_dom_sf
IPR000163	Prohibitin
IPR001107	Band_7

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR000163	Prohibitin	PRINTS	PR00679	PROHIBITIN	coord: 94..113 score: 58.46 coord: 117..135 score: 76.52 coord: 140..156 score: 69.23 coord: 188..211 score: 64.1 coord: 163..182 score: 60.0 coord: 211..227 score: 56.56 coord: 76..92 score: 68.78
IPR000163	Prohibitin	PANTHER	PTHR23222	PROHIBITIN	coord: 19..281
IPR000163	Prohibitin	CDD	cd03401	SPFH_prohibitin	coord: 33..227 e-value: 2.58086E-90 score: 264.761
IPR001107	Band 7 domain	SMART	SM00244	PHB_4	coord: 32..193 e-value: 1.2E-40 score: 151.0
IPR001107	Band 7 domain	PFAM	PF01145	Band_7	coord: 35..214 e-value: 4.3E-20 score: 72.5
None	No IPR available	PANTHER	PTHR23222:SF1	PROHIBITIN-2	coord: 19..281
IPR036013	Band 7/SPFH domain superfamily	SUPERFAMILY	SSF117892	Band 7/SPFH domain	coord: 64..199