HATPase_c domain-containing protein

Overview


Name	HATPase_c domain-containing protein
Smed ID	SMED30020593
Length (bp)	319

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of HATPase_c domain-containing protein (SMED30020593) t-SNE clustered cells

Violin plots show distribution of expression levels for HATPase_c domain-containing protein (SMED30020593) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of HATPase_c domain-containing protein (SMED30020593) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for HATPase_c domain-containing protein (SMED30020593) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30020593

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 31

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication	Lifecycle
head region	SMED30020593	h1SMcG0006787	SmedASXL_061618	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
Smed sexual biotype	SMED30020593	h1SMcG0006787	Contig31297	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020593	h1SMcG0006787	Contig31297	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020593	h1SMcG0006787	Contig32555	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020593	h1SMcG0006787	Contig32555	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020593	h1SMcG0006787	Contig38791	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020593	h1SMcG0006787	Contig38791	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020593	h1SMcG0006787	Contig39149	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020593	h1SMcG0006787	Contig39149	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020593	h1SMcG0006788	Contig39149	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020593	h1SMcG0006788	Contig39149	newmark_ests	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30020593	h1SMcG0006787	dd_Smed_v4_1693_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30020593	h1SMcG0006787	dd_Smed_v4_1693_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30020593	h1SMcG0006787	dd_Smed_v4_1693_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020593	h1SMcG0006787	Contig563	GPL15192	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30020593	h1SMcG0006787	dd_Smed_v4_3684_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30020593	h1SMcG0006787	dd_Smed_v4_3684_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30020593	h1SMcG0006787	dd_Smed_v4_2265_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30020593	h1SMcG0006787	dd_Smed_v4_2265_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30020593	h1SMcG0006787	dd_Smed_v4_2265_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30020593	h1SMcG0006787	dd_Smed_v4_2265_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30020593	h1SMcG0006787	dd_Smed_v4_2265_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020593	h1SMcG0019490	Contig563	GPL15192	PMID:29674431 Fincher et al., 2018
head region	SMED30020593	h1SMcG0006787	dd_Smed_v6_1693_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
pharynx musculature	SMED30020593	h1SMcG0006787	dd_Smed_v6_2265_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
musculature system	SMED30020593	h1SMcG0006787	dd_Smed_v6_2265_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
pharynx musculature	SMED30020593	h1SMcG0006787	dd_Smed_v6_1693_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
musculature system	SMED30020593	h1SMcG0006787	dd_Smed_v6_1693_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
reproductive organ	SMED30020593	h1SMcG0006787	Contig15693	newmark_ests	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30020593	h1SMcG0006787	Contig15693	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
testis primordium	SMED30020593	h1SMcG0006787	Contig5941_SE3	GPL10652	PMID:20844018 Wang et al., 2010	juvenile stage

Note: Hover over icons to view figure legend

Homology

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BLAST of HATPase_c domain-containing protein vs. Ensembl Human
Match: HSP90B1 (heat shock protein 90 beta family member 1 [Source:HGNC Symbol;Acc:HGNC:12028])

HSP 1 Score: 112.849 bits (281), Expect = 7.108e-30
Identity = 54/86 (62.79%), Postives = 64/86 (74.42%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEG 260
            +RF SSH     TSL  YV RMK  QDKI+F+AG S  + + SP VE LLKK YEV+YL EP+DEY  Q+LPEF+GK+FQNVAKEG
Sbjct:  510 LRFQSSHHPTDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEG 595

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BLAST of HATPase_c domain-containing protein vs. Ensembl Human
Match: HSP90AB1 (heat shock protein 90 alpha family class B member 1 [Source:HGNC Symbol;Acc:HGNC:5258])

HSP 1 Score: 80.4925 bits (197), Expect = 1.663e-18
Identity = 40/84 (47.62%), Postives = 55/84 (65.48%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAK 254
            +R+ +S S +  TSL++YVSRMK TQ  I++I G S   V  S  VE + K+ +EV+Y+ EPIDEY  Q L EF+GK   +V K
Sbjct:  455 LRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTK 538

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Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAK 254
            +R+ +S S +  TSL++YVSRMK TQ  I++I G S   V  S  VE + K+ +EV+Y+ EPIDEY  Q L EF+GK   +V K
Sbjct:  455 LRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTK 538

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Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAK 254
            +R+ +S S +  TSL++YVSRMK TQ  I++I G S   V  S  VE + K+ +EV+Y+ EPIDEY  Q L EF+GK   +V K
Sbjct:  455 LRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTK 538

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Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAK 254
            +R+ +S S +  TSL++YVSRMK TQ  I++I G S   V  S  VE + K+ +EV+Y+ EPIDEY  Q L EF+GK   +V K
Sbjct:  455 LRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTK 538

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BLAST of HATPase_c domain-containing protein vs. Ensembl Celegans
Match: enpl-1 (Endoplasmin homolog [Source:UniProtKB/Swiss-Prot;Acc:Q22235])

HSP 1 Score: 103.99 bits (258), Expect = 4.115e-27
Identity = 48/86 (55.81%), Postives = 63/86 (73.26%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEG 260
            +RF SS+  +  T+LA YV RMK  QD I+++AG S  +V+ SP VE L+ K YEVL+L E +DEY  Q++PE+E KKFQNVAKEG
Sbjct:  415 LRFQSSNDADKTTTLAAYVERMKEKQDAIYYMAGTSRKEVETSPFVERLIAKGYEVLFLTEAVDEYCIQAMPEYESKKFQNVAKEG 500

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Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEG 260
            +RF SS+  +  T+LA YV RMK  QD I+++AG S  +V+ SP VE L+ K YEVL+L E +DEY  Q++PE+E KKFQNVAKEG
Sbjct:  415 LRFQSSNDADKTTTLAAYVERMKEKQDAIYYMAGTSRKEVETSPFVERLIAKGYEVLFLTEAVDEYCIQAMPEYESKKFQNVAKEG 500

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Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEG 260
            +RF SS+  +  T+LA YV RMK  QD I+++AG S  +V+ SP VE L+ K YEVL+L E +DEY  Q++PE+E KKFQNVAKEG
Sbjct:  415 LRFQSSNDADKTTTLAAYVERMKEKQDAIYYMAGTSRKEVETSPFVERLIAKGYEVLFLTEAVDEYCIQAMPEYESKKFQNVAKEG 500

[Close]

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEG 260
            +RF SS+  +  T+LA YV RMK  QD I+++AG S  +V+ SP VE L+ K YEVL+L E +DEY  Q++PE+E KKFQNVAKEG
Sbjct:  415 LRFQSSNDADKTTTLAAYVERMKEKQDAIYYMAGTSRKEVETSPFVERLIAKGYEVLFLTEAVDEYCIQAMPEYESKKFQNVAKEG 500

[Close]

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEG 260
            +RF SS+  +  T+LA YV RMK  QD I+++AG S  +V+ SP VE L+ K YEVL+L E +DEY  Q++PE+E KKFQNVAKEG
Sbjct:  415 LRFQSSNDADKTTTLAAYVERMKEKQDAIYYMAGTSRKEVETSPFVERLIAKGYEVLFLTEAVDEYCIQAMPEYESKKFQNVAKEG 500

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BLAST of HATPase_c domain-containing protein vs. Ensembl Fly
Match: Gp93 (gene:FBgn0039562 transcript:FBtr0085254)

HSP 1 Score: 104.76 bits (260), Expect = 2.716e-27
Identity = 50/87 (57.47%), Postives = 66/87 (75.86%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEGF 263
            +RF +S+ +   TSLA+Y  RMK  Q+ I++IAG + ++V+ SP VE LL K YEVLYL+E +DEY   +LPEF+GKKFQNVAKEGF
Sbjct:  508 LRFQTSNGK-GVTSLAEYKERMKAKQEHIYYIAGANRAEVEKSPFVERLLSKGYEVLYLVEAVDEYCISALPEFDGKKFQNVAKEGF 593

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BLAST of HATPase_c domain-containing protein vs. Ensembl Fly
Match: Hsp83 (gene:FBgn0001233 transcript:FBtr0332873)

HSP 1 Score: 82.0333 bits (201), Expect = 2.002e-19
Identity = 41/87 (47.13%), Postives = 55/87 (63.22%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEGF 263
            +RF +S S +   SLADYVSRMK  Q  ++FI G S   V  S  VE +  + +EV+Y+ EPIDEY  Q L E++GK+  +V KEG 
Sbjct:  448 LRFHTSASGDDFCSLADYVSRMKDNQKHVYFITGESKDQVSNSAFVERVKARGFEVVYMTEPIDEYVIQHLKEYKGKQLVSVTKEGL 534

[Close]

BLAST of HATPase_c domain-containing protein vs. Ensembl Fly
Match: Hsp83 (gene:FBgn0001233 transcript:FBtr0073040)

HSP 1 Score: 82.0333 bits (201), Expect = 2.002e-19
Identity = 41/87 (47.13%), Postives = 55/87 (63.22%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEGF 263
            +RF +S S +   SLADYVSRMK  Q  ++FI G S   V  S  VE +  + +EV+Y+ EPIDEY  Q L E++GK+  +V KEG 
Sbjct:  448 LRFHTSASGDDFCSLADYVSRMKDNQKHVYFITGESKDQVSNSAFVERVKARGFEVVYMTEPIDEYVIQHLKEYKGKQLVSVTKEGL 534

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BLAST of HATPase_c domain-containing protein vs. Ensembl Zebrafish
Match: hsp90b1 (heat shock protein 90, beta (grp94), member 1 [Source:ZFIN;Acc:ZDB-GENE-031002-1])

HSP 1 Score: 113.62 bits (283), Expect = 2.861e-30
Identity = 53/86 (61.63%), Postives = 65/86 (75.58%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEG 260
            +RF +SHS    +SL  YV RMK  QDKI+F+AG S  + + SP VE LLKK YEV+YL EP+DEY  Q+LPEF+GK+FQNVAKEG
Sbjct:  510 LRFQTSHSDTVLSSLEQYVERMKEKQDKIYFMAGTSRKEAESSPFVEKLLKKGYEVVYLTEPVDEYCIQALPEFDGKRFQNVAKEG 595

[Close]

BLAST of HATPase_c domain-containing protein vs. Ensembl Zebrafish
Match: hsp90b1 (heat shock protein 90, beta (grp94), member 1 [Source:ZFIN;Acc:ZDB-GENE-031002-1])

HSP 1 Score: 113.62 bits (283), Expect = 3.014e-30
Identity = 53/86 (61.63%), Postives = 65/86 (75.58%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEG 260
            +RF +SHS    +SL  YV RMK  QDKI+F+AG S  + + SP VE LLKK YEV+YL EP+DEY  Q+LPEF+GK+FQNVAKEG
Sbjct:  511 LRFQTSHSDTVLSSLEQYVERMKEKQDKIYFMAGTSRKEAESSPFVEKLLKKGYEVVYLTEPVDEYCIQALPEFDGKRFQNVAKEG 596

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BLAST of HATPase_c domain-containing protein vs. Ensembl Zebrafish
Match: hsp90aa1.1 (heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1 [Source:NCBI gene;Acc:30591])

HSP 1 Score: 85.1149 bits (209), Expect = 2.483e-20
Identity = 42/87 (48.28%), Postives = 55/87 (63.22%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEGF 263
            +R+++S S +   SL DYVSRMK TQ  I++I G +   V  S  VE L K   EV+Y+IEPIDEY  Q L E++GK   +V KEG 
Sbjct:  456 LRYYTSASGDEMVSLKDYVSRMKDTQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKEYDGKNLVSVTKEGL 542

[Close]

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEGF 263
            +R+++S S +   SL DYVSRMK TQ  I++I G +   V  S  VE L K   EV+Y+IEPIDEY  Q L E++GK   +V KEG 
Sbjct:  456 LRYYTSASGDEMVSLKDYVSRMKDTQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKEYDGKNLVSVTKEGL 542

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BLAST of HATPase_c domain-containing protein vs. Ensembl Zebrafish
Match: hsp90ab1 (heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2 [Source:ZFIN;Acc:ZDB-GENE-031001-3])

HSP 1 Score: 85.1149 bits (209), Expect = 2.790e-20
Identity = 42/87 (48.28%), Postives = 55/87 (63.22%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEGF 263
            +R+ SS S +  TSL +YVSRMK  Q  I++I G S   V  S  VE + K+ +EVLY+ EPIDEY  Q L +F+GK   +V KEG 
Sbjct:  454 LRYQSSQSGDEMTSLTEYVSRMKENQKSIYYITGESKDQVAHSAFVERVCKRGFEVLYMTEPIDEYCVQQLKDFDGKSLVSVTKEGL 540

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BLAST of HATPase_c domain-containing protein vs. Ensembl Xenopus
Match: hsp90b1 (heat shock protein 90kDa beta (Grp94), member 1 [Source:NCBI gene;Acc:734089])

HSP 1 Score: 119.013 bits (297), Expect = 5.275e-32
Identity = 56/87 (64.37%), Postives = 68/87 (78.16%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEGF 263
            +RF SS+++   TSL  YV RMK  QDKI+FIAG S  +V+ SP VE LLKK YEVL+LIEP+DEY  Q+LPEF+GK+FQNVAKEG 
Sbjct:  482 LRFQSSNNKSETTSLEQYVERMKEKQDKIYFIAGASRKEVESSPFVERLLKKGYEVLFLIEPVDEYCIQALPEFDGKRFQNVAKEGL 568

[Close]

BLAST of HATPase_c domain-containing protein vs. Ensembl Xenopus
Match: hsp90b1 (heat shock protein 90kDa beta (Grp94), member 1 [Source:NCBI gene;Acc:734089])

HSP 1 Score: 118.627 bits (296), Expect = 5.983e-32
Identity = 56/87 (64.37%), Postives = 68/87 (78.16%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEGF 263
            +RF SS+++   TSL  YV RMK  QDKI+FIAG S  +V+ SP VE LLKK YEVL+LIEP+DEY  Q+LPEF+GK+FQNVAKEG 
Sbjct:  480 LRFQSSNNKSETTSLEQYVERMKEKQDKIYFIAGASRKEVESSPFVERLLKKGYEVLFLIEPVDEYCIQALPEFDGKRFQNVAKEGL 566

[Close]

BLAST of HATPase_c domain-containing protein vs. Ensembl Xenopus
Match: hsp90b1 (heat shock protein 90kDa beta (Grp94), member 1 [Source:NCBI gene;Acc:734089])

HSP 1 Score: 118.627 bits (296), Expect = 6.766e-32
Identity = 56/87 (64.37%), Postives = 68/87 (78.16%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEGF 263
            +RF SS+++   TSL  YV RMK  QDKI+FIAG S  +V+ SP VE LLKK YEVL+LIEP+DEY  Q+LPEF+GK+FQNVAKEG 
Sbjct:  509 LRFQSSNNKSETTSLEQYVERMKEKQDKIYFIAGASRKEVESSPFVERLLKKGYEVLFLIEPVDEYCIQALPEFDGKRFQNVAKEGL 595

[Close]

BLAST of HATPase_c domain-containing protein vs. Ensembl Xenopus
Match: hsp90b1 (heat shock protein 90kDa beta (Grp94), member 1 [Source:NCBI gene;Acc:734089])

HSP 1 Score: 118.627 bits (296), Expect = 7.165e-32
Identity = 56/87 (64.37%), Postives = 68/87 (78.16%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEGF 263
            +RF SS+++   TSL  YV RMK  QDKI+FIAG S  +V+ SP VE LLKK YEVL+LIEP+DEY  Q+LPEF+GK+FQNVAKEG 
Sbjct:  502 LRFQSSNNKSETTSLEQYVERMKEKQDKIYFIAGASRKEVESSPFVERLLKKGYEVLFLIEPVDEYCIQALPEFDGKRFQNVAKEGL 588

[Close]

BLAST of HATPase_c domain-containing protein vs. Ensembl Xenopus
Match: hsp90b1 (heat shock protein 90kDa beta (Grp94), member 1 [Source:NCBI gene;Acc:734089])

HSP 1 Score: 118.242 bits (295), Expect = 8.443e-32
Identity = 56/87 (64.37%), Postives = 68/87 (78.16%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEGF 263
            +RF SS+++   TSL  YV RMK  QDKI+FIAG S  +V+ SP VE LLKK YEVL+LIEP+DEY  Q+LPEF+GK+FQNVAKEG 
Sbjct:  511 LRFQSSNNKSETTSLEQYVERMKEKQDKIYFIAGASRKEVESSPFVERLLKKGYEVLFLIEPVDEYCIQALPEFDGKRFQNVAKEGL 597

[Close]

BLAST of HATPase_c domain-containing protein vs. Ensembl Mouse
Match: Hsp90b1 (heat shock protein 90, beta (Grp94), member 1 [Source:MGI Symbol;Acc:MGI:98817])

HSP 1 Score: 113.235 bits (282), Expect = 5.316e-31
Identity = 54/86 (62.79%), Postives = 64/86 (74.42%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEG 260
            +RF SSH     TSL  YV RMK  QDKI+F+AG S  + + SP VE LLKK YEV+YL EP+DEY  Q+LPEF+GK+FQNVAKEG
Sbjct:  186 LRFQSSHHSTDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEG 271

[Close]

BLAST of HATPase_c domain-containing protein vs. Ensembl Mouse
Match: Hsp90b1 (heat shock protein 90, beta (Grp94), member 1 [Source:MGI Symbol;Acc:MGI:98817])

HSP 1 Score: 113.62 bits (283), Expect = 2.916e-30
Identity = 54/86 (62.79%), Postives = 64/86 (74.42%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEG 260
            +RF SSH     TSL  YV RMK  QDKI+F+AG S  + + SP VE LLKK YEV+YL EP+DEY  Q+LPEF+GK+FQNVAKEG
Sbjct:  510 LRFQSSHHSTDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEG 595

[Close]

BLAST of HATPase_c domain-containing protein vs. Ensembl Mouse
Match: Hsp90ab1 (heat shock protein 90 alpha (cytosolic), class B member 1 [Source:MGI Symbol;Acc:MGI:96247])

HSP 1 Score: 80.4925 bits (197), Expect = 1.153e-18
Identity = 40/84 (47.62%), Postives = 55/84 (65.48%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAK 254
            +R+ +S S +  TSL++YVSRMK TQ  I++I G S   V  S  VE + K+ +EV+Y+ EPIDEY  Q L EF+GK   +V K
Sbjct:  455 LRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTK 538

[Close]

BLAST of HATPase_c domain-containing protein vs. Ensembl Mouse
Match: Hsp90aa1 (heat shock protein 90, alpha (cytosolic), class A member 1 [Source:MGI Symbol;Acc:MGI:96250])

HSP 1 Score: 79.337 bits (194), Expect = 2.935e-18
Identity = 40/84 (47.62%), Postives = 51/84 (60.71%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAK 254
            +R+++S S +   SL DY +RMK  Q  I+FI G +   V  S  VE L K   EV+Y+IEPIDEY  Q L EFEGK   +V K
Sbjct:  464 LRYYTSASGDEMVSLKDYCTRMKENQKHIYFITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTK 547

[Close]

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAK 254
            +R+++S S +   SL DY +RMK  Q  I+FI G +   V  S  VE L K   EV+Y+IEPIDEY  Q L EFEGK   +V K
Sbjct:  464 LRYYTSASGDEMVSLKDYCTRMKENQKHIYFITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTK 547

[Close]

BLAST of HATPase_c domain-containing protein vs. UniProt/SwissProt
Match: sp|P08110|ENPL_CHICK (Endoplasmin OS=Gallus gallus OX=9031 GN=HSP90B1 PE=1 SV=1)

HSP 1 Score: 116.701 bits (291), Expect = 1.849e-30
Identity = 54/86 (62.79%), Postives = 66/86 (76.74%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEG 260
            +RF SSH + + TSL  YV RMK  QDKI+F+AG S  + + SP VE LLKK YEV+YL EP+DEY  Q+LPEF+GK+FQNVAKEG
Sbjct:  509 LRFQSSHHESNLTSLDQYVERMKEKQDKIYFMAGASRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEG 594

[Close]

BLAST of HATPase_c domain-containing protein vs. UniProt/SwissProt
Match: sp|P08712|ENPL_MESAU (Endoplasmin (Fragment) OS=Mesocricetus auratus OX=10036 GN=HSP90B1 PE=1 SV=1)

HSP 1 Score: 114.005 bits (284), Expect = 2.725e-30
Identity = 54/86 (62.79%), Postives = 64/86 (74.42%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEG 260
            +RF SSH     TSL  YV RMK  QDKI+F+AG S  + + SP VE LLKK YEV+YL EP+DEY  Q+LPEF+GK+FQNVAKEG
Sbjct:  107 LRFQSSHHSTDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEG 192

[Close]

BLAST of HATPase_c domain-containing protein vs. UniProt/SwissProt
Match: sp|Q95M18|ENPL_BOVIN (Endoplasmin OS=Bos taurus OX=9913 GN=HSP90B1 PE=2 SV=1)

HSP 1 Score: 115.161 bits (287), Expect = 5.941e-30
Identity = 54/86 (62.79%), Postives = 64/86 (74.42%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEG 260
            +RF SSH     TSL  YV RMK  QDKI+F+AG S  + + SP VE LLKK YEV+YL EP+DEY  Q+LPEF+GK+FQNVAKEG
Sbjct:  510 LRFQSSHHPSDMTSLDQYVERMKEKQDKIYFMAGASRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEG 595

[Close]

BLAST of HATPase_c domain-containing protein vs. UniProt/SwissProt
Match: sp|O18750|ENPL_RABIT (Endoplasmin (Fragment) OS=Oryctolagus cuniculus OX=9986 GN=HSP90B1 PE=2 SV=1)

HSP 1 Score: 113.62 bits (283), Expect = 1.937e-29
Identity = 54/86 (62.79%), Postives = 64/86 (74.42%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEG 260
            +RF SSH     TSL  YV RMK  QDKI+F+AG S  + + SP VE LLKK YEV+YL EP+DEY  Q+LPEF+GK+FQNVAKEG
Sbjct:  429 LRFQSSHHPTDITSLDQYVERMKEKQDKIYFMAGASRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEG 514

[Close]

BLAST of HATPase_c domain-containing protein vs. UniProt/SwissProt
Match: sp|P08113|ENPL_MOUSE (Endoplasmin OS=Mus musculus OX=10090 GN=Hsp90b1 PE=1 SV=2)

HSP 1 Score: 113.62 bits (283), Expect = 2.040e-29
Identity = 54/86 (62.79%), Postives = 64/86 (74.42%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEG 260
            +RF SSH     TSL  YV RMK  QDKI+F+AG S  + + SP VE LLKK YEV+YL EP+DEY  Q+LPEF+GK+FQNVAKEG
Sbjct:  510 LRFQSSHHSTDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEG 595

[Close]

BLAST of HATPase_c domain-containing protein vs. TrEMBL
Match: A0A2R4NBU5 (Heat shock protein 902 OS=Dugesia japonica OX=6161 GN=hsp902 PE=2 SV=1)

HSP 1 Score: 162.54 bits (410), Expect = 3.593e-44
Identity = 73/87 (83.91%), Postives = 82/87 (94.25%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEGF 263
            ++FWSSHS+E+ TSL+DY+SRMKP QDKIFFIAGVSL+DVQLSPMVE LLK QYEVLYLIEP+DEYT QS+PEFEGKKFQNVAKEGF
Sbjct:  522 LKFWSSHSEENLTSLSDYISRMKPNQDKIFFIAGVSLADVQLSPMVETLLKDQYEVLYLIEPVDEYTLQSIPEFEGKKFQNVAKEGF 608

[Close]

BLAST of HATPase_c domain-containing protein vs. TrEMBL
Match: A0A3M6TBK7 (HATPase_c domain-containing protein OS=Pocillopora damicornis OX=46731 GN=pdam_00012456 PE=3 SV=1)

HSP 1 Score: 126.716 bits (317), Expect = 1.603e-31
Identity = 60/87 (68.97%), Postives = 71/87 (81.61%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEGF 263
            +RF+SS+S++  TSLADY+ RMK  QD I+F+AG S  +V+ SP VE LLKK YEVLYLIEP+DEY  QSLPEFEGKKFQNVAKEG 
Sbjct:  566 LRFFSSNSEKDMTSLADYLERMKEKQDAIYFMAGTSRKEVESSPFVERLLKKGYEVLYLIEPVDEYCIQSLPEFEGKKFQNVAKEGL 652

[Close]

BLAST of HATPase_c domain-containing protein vs. TrEMBL
Match: T2MGW5 (Endoplasmin (Fragment) OS=Hydra vulgaris OX=6087 GN=HSP90B1 PE=2 SV=1)

HSP 1 Score: 126.331 bits (316), Expect = 2.375e-31
Identity = 61/87 (70.11%), Postives = 69/87 (79.31%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEGF 263
            +RF SS+  E  TSLADY+ RMK  QD IFF+AG SL +V+ SP VE LL+K YEVLYLIEP+DEY  QSLPEFEGKKFQNVAKEG 
Sbjct:  545 LRFRSSNDPEKMTSLADYLGRMKDKQDVIFFMAGASLEEVKNSPFVERLLRKGYEVLYLIEPVDEYCIQSLPEFEGKKFQNVAKEGL 631

[Close]

BLAST of HATPase_c domain-containing protein vs. TrEMBL
Match: A5LGG7 (Glucose-regulated protein 94 OS=Crassostrea gigas OX=29159 GN=GRP94 PE=2 SV=1)

HSP 1 Score: 125.176 bits (313), Expect = 5.732e-31
Identity = 59/87 (67.82%), Postives = 70/87 (80.46%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEGF 263
            +RF+SS+S   QTSL DYV RMK  Q+ I+F+AG S S+V+ SP VE LLKK YEVL+L+EP+DEY  QSLPEFEGKKFQNVAKEG 
Sbjct:  512 LRFYSSNSDTEQTSLPDYVERMKEKQEAIYFVAGTSRSEVEKSPFVERLLKKGYEVLFLVEPVDEYCIQSLPEFEGKKFQNVAKEGL 598

[Close]

BLAST of HATPase_c domain-containing protein vs. TrEMBL
Match: T1RTR8 (Tumor rejection antigen (Fragment) OS=Carassius auratus OX=7957 PE=2 SV=1)

HSP 1 Score: 115.931 bits (289), Expect = 8.873e-31
Identity = 53/86 (61.63%), Postives = 66/86 (76.74%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEG 260
            +RF +SHS  + +SL  YV RMK  QDKI+F+AG S  + + SP VE LLKK YEV+YL EP+DEY  Q+LPEF+GK+FQNVAKEG
Sbjct:   51 LRFQTSHSDTTPSSLEQYVERMKEKQDKIYFMAGTSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEG 136

[Close]

BLAST of HATPase_c domain-containing protein vs. Ensembl Cavefish
Match: hsp90b1 (heat shock protein 90, beta (grp94), member 1 [Source:ZFIN;Acc:ZDB-GENE-031002-1])

HSP 1 Score: 114.39 bits (285), Expect = 1.327e-30
Identity = 53/86 (61.63%), Postives = 66/86 (76.74%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEG 260
            +RF +SHS+   +SL  YV RMK  QDKI+F+AG S  + + SP VE LLKK YEV+YL EP+DEY  Q+LPEF+GK+FQNVAKEG
Sbjct:  505 LRFQTSHSETVLSSLEQYVERMKEKQDKIYFMAGTSRKEAESSPFVEKLLKKGYEVVYLTEPVDEYCIQALPEFDGKRFQNVAKEG 590

[Close]

BLAST of HATPase_c domain-containing protein vs. Ensembl Cavefish
Match: hsp90aa1.2 (Astyanax mexicanus heat shock protein HSP 90-alpha 1-like (LOC103024454), mRNA. [Source:RefSeq mRNA;Acc:NM_001291257])

HSP 1 Score: 84.7297 bits (208), Expect = 3.195e-20
Identity = 41/87 (47.13%), Postives = 56/87 (64.37%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEGF 263
            +R+++S+S +   SL DYVSRMK +Q  I++I G +   V  S  VE L K   EV+Y+IEPIDEY  Q L E++GK   +V KEG 
Sbjct:  454 LRYYTSNSGDEMVSLKDYVSRMKDSQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKEYDGKNLLSVTKEGL 540

[Close]

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEGF 263
            +R+++S+S +   SL DYVSRMK +Q  I++I G +   V  S  VE L K   EV+Y+IEPIDEY  Q L E++GK   +V KEG 
Sbjct:  454 LRYYTSNSGDEMVSLKDYVSRMKDSQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKEYDGKNLLSVTKEGL 540

[Close]

BLAST of HATPase_c domain-containing protein vs. Ensembl Cavefish
Match: hsp90ab1 (heat shock protein 90 alpha family class B member 1 [Source:NCBI gene;Acc:103047517])

HSP 1 Score: 84.3445 bits (207), Expect = 4.405e-20
Identity = 42/87 (48.28%), Postives = 56/87 (64.37%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEGF 263
            +R+ SS S +  TSL++Y+SRMK  Q  I++I G S   V  S  VE + K+ +EVLY+ EPIDEY  Q L EF+GK   +V KEG 
Sbjct:  455 LRYHSSQSGDEMTSLSEYLSRMKENQKSIYYITGESKDQVANSAFVERVRKRGFEVLYMTEPIDEYCVQQLKEFDGKTLVSVTKEGL 541

[Close]

BLAST of HATPase_c domain-containing protein vs. Ensembl Cavefish
Match: hsp90aa1.2 (Astyanax mexicanus heat shock protein HSP 90-alpha 1-like (LOC103024454), mRNA. [Source:RefSeq mRNA;Acc:NM_001291257])

HSP 1 Score: 81.6481 bits (200), Expect = 4.083e-19
Identity = 41/84 (48.81%), Postives = 53/84 (63.10%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAK 254
            +R+++S S +   SL DYV+RMK TQ  I++I G +   V  S  VE L K   EV+Y+IEPIDEY  Q L EFEGK   +V K
Sbjct:  462 LRYYTSASGDEMVSLKDYVTRMKDTQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKEFEGKNLVSVTK 545

[Close]

BLAST of HATPase_c domain-containing protein vs. Ensembl Sea Lamprey
Match: hsp90b1 (heat shock protein 90, beta (grp94), member 1 [Source:ZFIN;Acc:ZDB-GENE-031002-1])

HSP 1 Score: 81.6481 bits (200), Expect = 8.082e-20
Identity = 40/70 (57.14%), Postives = 50/70 (71.43%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQS 212
            +RF SS+  +  TSL +YV RMK  QDKI+FIAG +  +V+ SP VE LLKK YEVL+L E +DEY  QS
Sbjct:  487 LRFQSSYGTDKLTSLEEYVERMKEKQDKIYFIAGANRKEVESSPFVERLLKKGYEVLFLTEAVDEYCIQS 556

[Close]

BLAST of HATPase_c domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003399.1 (pep scaffold:Pmarinus_7.0:GL479675:6143:15195:1 gene:ENSPMAG00000002912.1 transcript:ENSPMAT00000003399.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 78.1814 bits (191), Expect = 1.345e-18
Identity = 40/87 (45.98%), Postives = 53/87 (60.92%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEGF 263
            +R+ +S + E   SL +YVSRMK  Q  I++I G S   V  S  VE + K+  EV+Y+ EPIDEY  Q L EF+GK   +V KEG 
Sbjct:  433 LRYHTSVTGEDVCSLKEYVSRMKENQKHIYYITGESKEQVSNSAFVERVRKRGLEVVYMTEPIDEYCVQQLKEFDGKTLVSVTKEGL 519

[Close]

BLAST of HATPase_c domain-containing protein vs. Ensembl Yeast
Match: HSC82 (Cytoplasmic chaperone of the Hsp90 family; plays a role in determining prion variants; redundant in function and nearly identical with Hsp82p, and together they are essential; expressed constitutively at 10-fold higher basal levels than HSP82 and induced 2-3 fold by heat shock; contains two acid-rich unstructured regions that promote the solubility of chaperone-substrate complexes; HSC82 has a paralog, HSP82, that arose from the whole genome duplication [Source:SGD;Acc:S000004798])

HSP 1 Score: 80.4925 bits (197), Expect = 1.241e-19
Identity = 39/85 (45.88%), Postives = 55/85 (64.71%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKE 257
            +R+ S+ S +  TSL DYV+RM   Q  I++I G SL  V+ SP ++ L  K +EVL+L +PIDEY F  L EFEGK   ++ K+
Sbjct:  439 LRYNSTKSVDELTSLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYAFTQLKEFEGKTLVDITKD 523

[Close]

BLAST of HATPase_c domain-containing protein vs. Ensembl Yeast
Match: HSP82 (Hsp90 chaperone; redundant in function with Hsc82p; required for pheromone signaling, negative regulation of Hsf1p; docks with Tom70p for mitochondrial preprotein delivery; promotes telomerase DNA binding, nucleotide addition; protein abundance increases in response to DNA replication stress; contains two acid-rich unstructured regions that promote solubility of chaperone-substrate complexes; HSP82 has a paralog, HSC82, that arose from the whole genome duplication [Source:SGD;Acc:S000006161])

HSP 1 Score: 80.4925 bits (197), Expect = 1.253e-19
Identity = 39/85 (45.88%), Postives = 55/85 (64.71%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKE 257
            +R+ S+ S +  TSL DYV+RM   Q  I++I G SL  V+ SP ++ L  K +EVL+L +PIDEY F  L EFEGK   ++ K+
Sbjct:  443 LRYNSTKSVDELTSLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYAFTQLKEFEGKTLVDITKD 527

[Close]

BLAST of HATPase_c domain-containing protein vs. Ensembl Nematostella
Match: EDO45344 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RT97])

HSP 1 Score: 120.939 bits (302), Expect = 2.038e-33
Identity = 57/87 (65.52%), Postives = 71/87 (81.61%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEGF 263
            +RF+SS+S++  TSLA+Y+ RMK  QD I+F+AG +  +V+ SP VE LLK+ YEVLYLIEP+DEY  QSLPEFEGKKFQNVAKEG 
Sbjct:  526 LRFYSSNSEKDMTSLAEYIERMKEKQDVIYFMAGHNRKEVESSPFVEKLLKEGYEVLYLIEPVDEYCMQSLPEFEGKKFQNVAKEGL 612

[Close]

BLAST of HATPase_c domain-containing protein vs. Ensembl Nematostella
Match: HSP90 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJ66])

HSP 1 Score: 87.0409 bits (214), Expect = 1.933e-21
Identity = 43/87 (49.43%), Postives = 56/87 (64.37%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEGF 263
            +R+ SS S +  TSL DYV+RMK  Q  I+FI G S   V  S  VE +  + +EVLY++EPIDEY  Q L E++GKK  +V KEG 
Sbjct:  457 LRYHSSSSGDELTSLKDYVTRMKENQKDIYFITGESKDQVSHSAFVERVKSRGFEVLYMVEPIDEYAIQQLKEYDGKKLVSVTKEGL 543

[Close]

BLAST of HATPase_c domain-containing protein vs. Ensembl Nematostella
Match: EDO45666 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RS03])

HSP 1 Score: 46.2098 bits (108), Expect = 3.800e-7
Identity = 24/65 (36.92%), Postives = 35/65 (53.85%), Query Frame = 3

Query:   39 TSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGK 233
            T+L  YVSRMKPTQ K++++   S    + SP  E L +   EVL+     D+     L ++E K
Sbjct:  409 TNLPAYVSRMKPTQKKVYYLCAPSRDLAETSPYYETLKQNDVEVLFSYNEQDDVVLHYLRKYENK 473

[Close]

BLAST of HATPase_c domain-containing protein vs. Ensembl Medaka
Match: hsp90b1 (heat shock protein 90 beta family member 1 [Source:NCBI gene;Acc:101166123])

HSP 1 Score: 112.079 bits (279), Expect = 7.658e-30
Identity = 52/86 (60.47%), Postives = 65/86 (75.58%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEG 260
            +RF +S+S+    SL  YV RMK  QDKI+F+AG S  + + SP VE LLKK YEV+YL EP+DEY  Q+LPEF+GK+FQNVAKEG
Sbjct:  514 LRFQTSNSETGLASLEQYVERMKEKQDKIYFMAGTSRKEAESSPFVEKLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEG 599

[Close]

BLAST of HATPase_c domain-containing protein vs. Ensembl Medaka
Match: hsp90ab1 (heat shock protein 90 alpha family class B member 1 [Source:NCBI gene;Acc:100125466])

HSP 1 Score: 84.3445 bits (207), Expect = 3.710e-20
Identity = 42/87 (48.28%), Postives = 55/87 (63.22%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEGF 263
            +R+ SS S +  TSL +Y+SRMK  Q  I++I G S   V  S  VE + K+ +EVLY+ EPIDEY  Q L EF+GK   +V KEG 
Sbjct:  452 LRYHSSQSGDEMTSLTEYLSRMKENQKSIYYITGESKDQVANSAFVERVRKRGFEVLYMTEPIDEYCVQQLKEFDGKNLVSVTKEGL 538

[Close]

BLAST of HATPase_c domain-containing protein vs. Ensembl Medaka
Match: hsp90ab1 (heat shock protein 90 alpha family class B member 1 [Source:NCBI gene;Acc:100125466])

HSP 1 Score: 84.3445 bits (207), Expect = 4.043e-20
Identity = 42/87 (48.28%), Postives = 55/87 (63.22%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEGF 263
            +R+ SS S +  TSL +Y+SRMK  Q  I++I G S   V  S  VE + K+ +EVLY+ EPIDEY  Q L EF+GK   +V KEG 
Sbjct:  452 LRYHSSQSGDEMTSLTEYLSRMKENQKSIYYITGESKDQVANSAFVERVRKRGFEVLYMTEPIDEYCVQQLKEFDGKNLVSVTKEGL 538

[Close]

BLAST of HATPase_c domain-containing protein vs. Ensembl Medaka
Match: hsp90aa1.2 (heat shock protein HSP 90-alpha [Source:NCBI gene;Acc:101169506])

HSP 1 Score: 78.5666 bits (192), Expect = 4.432e-18
Identity = 39/84 (46.43%), Postives = 52/84 (61.90%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAK 254
            +R+++S S +   SL DYVSRMK  Q  I++I G +   V  S  VE L K   EV+Y+IEPIDEY  Q L +F+GK   +V K
Sbjct:  455 LRYYTSASGDEMVSLKDYVSRMKDNQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKDFDGKNLVSVTK 538

[Close]

BLAST of HATPase_c domain-containing protein vs. Ensembl Medaka
Match: hsp90aa1.2 (heat shock protein HSP 90-alpha [Source:NCBI gene;Acc:101169506])

HSP 1 Score: 77.7962 bits (190), Expect = 9.190e-18
Identity = 38/84 (45.24%), Postives = 52/84 (61.90%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAK 254
            +R+++S S +   SL DYV+RMK  Q  I++I G +   V  S  VE L K   EV+Y+IEPIDEY  Q L +F+GK   +V K
Sbjct:  455 LRYYTSASGDEMVSLKDYVTRMKDNQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKDFDGKNLVSVTK 538

[Close]

BLAST of HATPase_c domain-containing protein vs. Planmine SMEST
Match: SMESG000054819.1 (SMESG000054819.1)

HSP 1 Score: 181.8 bits (460), Expect = 8.357e-55
Identity = 87/87 (100.00%), Postives = 87/87 (100.00%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEGF 263
            IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEGF
Sbjct:  515 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEGF 601

[Close]

BLAST of HATPase_c domain-containing protein vs. Planmine SMEST
Match: SMESG000041107.1 (SMESG000041107.1)

HSP 1 Score: 112.464 bits (280), Expect = 4.437e-30
Identity = 50/86 (58.14%), Postives = 68/86 (79.07%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEG 260
            +RFW+SH+ + Q++L DYVSRMK  Q+ I++IAG S  D+  SP+VE +LKK +EV+Y+I+P+DEY  QSL EFEGKK QN+ KEG
Sbjct:  511 LRFWTSHNDKKQSTLTDYVSRMKEKQEVIYYIAGHSKDDLIKSPLVEKVLKKGFEVVYMIDPVDEYVVQSLTEFEGKKMQNLGKEG 596

[Close]

BLAST of HATPase_c domain-containing protein vs. Planmine SMEST
Match: SMESG000071533.1 (SMESG000071533.1)

HSP 1 Score: 88.5817 bits (218), Expect = 9.122e-22
Identity = 43/87 (49.43%), Postives = 58/87 (66.67%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEGF 263
            +RF+S+ S E  TSL DY+SRMK  Q  I++I G S  +V  S  VE L K+ +EVL +++PIDEY+ Q L E++GKK   V KEG 
Sbjct:  447 LRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTKEGL 533

[Close]

BLAST of HATPase_c domain-containing protein vs. Planmine SMEST
Match: SMESG000071531.1 (SMESG000071531.1)

HSP 1 Score: 87.8113 bits (216), Expect = 1.663e-21
Identity = 42/87 (48.28%), Postives = 58/87 (66.67%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEGF 263
            +RF+S+ S E  TSL DY++RMK  Q  I++I G S  +V  S  VE L K+ +EVL +++PIDEY+ Q L E++GKK   V KEG 
Sbjct:  428 LRFYSTSSGEEMTSLKDYITRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTKEGL 514

[Close]

BLAST of HATPase_c domain-containing protein vs. Planmine SMEST
Match: SMESG000024822.1 (SMESG000024822.1)

HSP 1 Score: 85.1149 bits (209), Expect = 1.652e-20
Identity = 42/84 (50.00%), Postives = 56/84 (66.67%), Query Frame = 3

Query:    3 IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAK 254
            +R+ S+ S E  TSL DY+SRMK  Q  I++I G S  +V  S  VE L K+ +EVLY+I+PIDEY+ Q L E++GKK   V K
Sbjct:  446 LRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTK 529

The following BLAST results are available for this feature:

BLAST of HATPase_c domain-containing protein vs. Ensembl Human
BLAST of HATPase_c domain-containing protein vs. Ensembl Celegans
BLAST of HATPase_c domain-containing protein vs. Ensembl Fly
BLAST of HATPase_c domain-containing protein vs. Ensembl Zebrafish
BLAST of HATPase_c domain-containing protein vs. Ensembl Xenopus
BLAST of HATPase_c domain-containing protein vs. Ensembl Mouse
BLAST of HATPase_c domain-containing protein vs. UniProt/SwissProt
BLAST of HATPase_c domain-containing protein vs. TrEMBL
BLAST of HATPase_c domain-containing protein vs. Ensembl Cavefish
BLAST of HATPase_c domain-containing protein vs. Ensembl Sea Lamprey
BLAST of HATPase_c domain-containing protein vs. Ensembl Yeast
BLAST of HATPase_c domain-containing protein vs. Ensembl Nematostella
BLAST of HATPase_c domain-containing protein vs. Ensembl Medaka
BLAST of HATPase_c domain-containing protein vs. Planmine SMEST

BLAST of HATPase_c domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
HSP90B1	7.108e-30	62.79	heat shock protein 90 beta family member 1 [Source...	[more]
HSP90AB1	1.663e-18	47.62	heat shock protein 90 alpha family class B member ...	[more]
HSP90AB1	1.663e-18	47.62	heat shock protein 90 alpha family class B member ...	[more]
HSP90AB1	1.663e-18	47.62	heat shock protein 90 alpha family class B member ...	[more]
HSP90AB1	1.663e-18	47.62	heat shock protein 90 alpha family class B member ...	[more]

BLAST of HATPase_c domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
enpl-1	4.115e-27	55.81	Endoplasmin homolog [Source:UniProtKB/Swiss-Prot;...	[more]
enpl-1	4.115e-27	55.81	Endoplasmin homolog [Source:UniProtKB/Swiss-Prot;...	[more]
enpl-1	4.115e-27	55.81	Endoplasmin homolog [Source:UniProtKB/Swiss-Prot;...	[more]
enpl-1	4.115e-27	55.81	Endoplasmin homolog [Source:UniProtKB/Swiss-Prot;...	[more]
enpl-1	4.115e-27	55.81	Endoplasmin homolog [Source:UniProtKB/Swiss-Prot;...	[more]

BLAST of HATPase_c domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3


Match Name	E-value	Identity	Description
Gp93	2.716e-27	57.47	gene:FBgn0039562 transcript:FBtr0085254	[more]
Hsp83	2.002e-19	47.13	gene:FBgn0001233 transcript:FBtr0332873	[more]
Hsp83	2.002e-19	47.13	gene:FBgn0001233 transcript:FBtr0073040	[more]

BLAST of HATPase_c domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
hsp90b1	2.861e-30	61.63	heat shock protein 90, beta (grp94), member 1 [Sou...	[more]
hsp90b1	3.014e-30	61.63	heat shock protein 90, beta (grp94), member 1 [Sou...	[more]
hsp90aa1.1	2.483e-20	48.28	heat shock protein 90, alpha (cytosolic), class A ...	[more]
hsp90aa1.1	2.483e-20	48.28	heat shock protein 90, alpha (cytosolic), class A ...	[more]
hsp90ab1	2.790e-20	48.28	heat shock protein 90, alpha (cytosolic), class A ...	[more]

BLAST of HATPase_c domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
hsp90b1	5.275e-32	64.37	heat shock protein 90kDa beta (Grp94), member 1 [S...	[more]
hsp90b1	5.983e-32	64.37	heat shock protein 90kDa beta (Grp94), member 1 [S...	[more]
hsp90b1	6.766e-32	64.37	heat shock protein 90kDa beta (Grp94), member 1 [S...	[more]
hsp90b1	7.165e-32	64.37	heat shock protein 90kDa beta (Grp94), member 1 [S...	[more]
hsp90b1	8.443e-32	64.37	heat shock protein 90kDa beta (Grp94), member 1 [S...	[more]

BLAST of HATPase_c domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Hsp90b1	5.316e-31	62.79	heat shock protein 90, beta (Grp94), member 1 [Sou...	[more]
Hsp90b1	2.916e-30	62.79	heat shock protein 90, beta (Grp94), member 1 [Sou...	[more]
Hsp90ab1	1.153e-18	47.62	heat shock protein 90 alpha (cytosolic), class B m...	[more]
Hsp90aa1	2.935e-18	47.62	heat shock protein 90, alpha (cytosolic), class A ...	[more]
Hsp90aa1	2.935e-18	47.62	heat shock protein 90, alpha (cytosolic), class A ...	[more]

BLAST of HATPase_c domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P08110\|ENPL_CHICK	1.849e-30	62.79	Endoplasmin OS=Gallus gallus OX=9031 GN=HSP90B1 PE...	[more]
sp\|P08712\|ENPL_MESAU	2.725e-30	62.79	Endoplasmin (Fragment) OS=Mesocricetus auratus OX=...	[more]
sp\|Q95M18\|ENPL_BOVIN	5.941e-30	62.79	Endoplasmin OS=Bos taurus OX=9913 GN=HSP90B1 PE=2 ...	[more]
sp\|O18750\|ENPL_RABIT	1.937e-29	62.79	Endoplasmin (Fragment) OS=Oryctolagus cuniculus OX...	[more]
sp\|P08113\|ENPL_MOUSE	2.040e-29	62.79	Endoplasmin OS=Mus musculus OX=10090 GN=Hsp90b1 PE...	[more]

BLAST of HATPase_c domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A2R4NBU5	3.593e-44	83.91	Heat shock protein 902 OS=Dugesia japonica OX=6161...	[more]
A0A3M6TBK7	1.603e-31	68.97	HATPase_c domain-containing protein OS=Pocillopora...	[more]
T2MGW5	2.375e-31	70.11	Endoplasmin (Fragment) OS=Hydra vulgaris OX=6087 G...	[more]
A5LGG7	5.732e-31	67.82	Glucose-regulated protein 94 OS=Crassostrea gigas ...	[more]
T1RTR8	8.873e-31	61.63	Tumor rejection antigen (Fragment) OS=Carassius au...	[more]

BLAST of HATPase_c domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
hsp90b1	1.327e-30	61.63	heat shock protein 90, beta (grp94), member 1 [Sou...	[more]
hsp90aa1.2	3.195e-20	47.13	Astyanax mexicanus heat shock protein HSP 90-alpha...	[more]
hsp90aa1.2	3.195e-20	47.13	Astyanax mexicanus heat shock protein HSP 90-alpha...	[more]
hsp90ab1	4.405e-20	48.28	heat shock protein 90 alpha family class B member ...	[more]
hsp90aa1.2	4.083e-19	48.81	Astyanax mexicanus heat shock protein HSP 90-alpha...	[more]

BLAST of HATPase_c domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
hsp90b1	8.082e-20	57.14	heat shock protein 90, beta (grp94), member 1 [Sou...	[more]
ENSPMAT00000003399.1	1.345e-18	45.98	pep scaffold:Pmarinus_7.0:GL479675:6143:15195:1 ge...	[more]

BLAST of HATPase_c domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2


Match Name	E-value	Identity	Description
HSC82	1.241e-19	45.88	Cytoplasmic chaperone of the Hsp90 family; plays a...	[more]
HSP82	1.253e-19	45.88	Hsp90 chaperone; redundant in function with Hsc82p...	[more]

BLAST of HATPase_c domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 3


Match Name	E-value	Identity	Description
EDO45344	2.038e-33	65.52	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
HSP90	1.933e-21	49.43	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO45666	3.800e-7	36.92	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of HATPase_c domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
hsp90b1	7.658e-30	60.47	heat shock protein 90 beta family member 1 [Source...	[more]
hsp90ab1	3.710e-20	48.28	heat shock protein 90 alpha family class B member ...	[more]
hsp90ab1	4.043e-20	48.28	heat shock protein 90 alpha family class B member ...	[more]
hsp90aa1.2	4.432e-18	46.43	heat shock protein HSP 90-alpha [Source:NCBI gene;...	[more]
hsp90aa1.2	9.190e-18	45.24	heat shock protein HSP 90-alpha [Source:NCBI gene;...	[more]

BLAST of HATPase_c domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000054819.1	8.357e-55	100.00	SMESG000054819.1	[more]
SMESG000041107.1	4.437e-30	58.14	SMESG000041107.1	[more]
SMESG000071533.1	9.122e-22	49.43	SMESG000071533.1	[more]
SMESG000071531.1	1.663e-21	48.28	SMESG000071531.1	[more]
SMESG000024822.1	1.652e-20	50.00	SMESG000024822.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30020593 ID=SMED30020593|Name=HATPase_c domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=319bp
TAATTCGGTTTTGGTCGTCACATTCTCAAGAAAGTCAAACATCTCTCGCT
GACTACGTTTCGAGGATGAAACCAACTCAAGACAAAATATTTTTTATTGC
CGGAGTATCTTTGAGTGATGTCCAGCTGTCACCAATGGTGGAAATACTCT
TGAAAAAACAATATGAAGTCCTTTATTTAATCGAACCGATCGATGAGTAC
ACTTTTCAATCATTACCGGAATTTGAAGGAAAGAAATTTCAAAACGTTGC
AAAAGAAGGCTTCAAACTGGACGATTCTGACAAAAAAATAGAAATCAAAG
AAAAGTTGGAGAAAGAATA

protein sequence of SMED30020593-orf-1

>SMED30020593-orf-1 ID=SMED30020593-orf-1|Name=SMED30020593-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=105bp
IRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILL
KKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEGFKLDDSDKKIEIKE
KLEKE

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0016021	integral component of membrane

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0002089	reproductive organ
PLANA:0003304	testis primordium

Vocabulary: **INTERPRO**
Term	Definition
IPR001404	Hsp90_fam
IPR020568	Ribosomal_S5_D2-typ_fold

Vocabulary: **molecular function**
Term	Definition
GO:0005524	ATP binding
GO:0051082	unfolded protein binding

Vocabulary: **biological process**
Term	Definition
GO:0006457	protein folding
GO:0006950	response to stress

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001404	Heat shock protein Hsp90 family	PFAM	PF00183	HSP90	coord: 1..104 e-value: 3.2E-37 score: 128.6
IPR001404	Heat shock protein Hsp90 family	PANTHER	PTHR11528	HEAT SHOCK PROTEIN 90 FAMILY MEMBER	coord: 1..105
None	No IPR available	GENE3D	G3DSA:3.40.50.11260		coord: 3..95 e-value: 1.2E-32 score: 113.6
None	No IPR available	PANTHER	PTHR11528:SF96	ENDOPLASMIN	coord: 1..105
IPR020568	Ribosomal protein S5 domain 2-type fold	SUPERFAMILY	SSF54211	Ribosomal protein S5 domain 2-like	coord: 1..85