asic

Overview
Nameasic (AGS83418.1)
Smed IDSMED30020592
Length (bp)1700
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of asic (SMED30020592) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for asic (SMED30020592) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30020592

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30020592h1SMcG0013456 dd_Smed_v4_9633_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30020592h1SMcG0013456 dd_Smed_v4_9633_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30020592h1SMcG0013456 dd_Smed_v4_9633_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
ventral region of the whole animalSMED30020592h1SMcG0013456 KF134121smed_ncbi_20240424PMID:23903188
Currie et al., 2013		whole organism asexual adult colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of asic vs. Ensembl Celegans
Match: unc-105 (Degenerin-like protein unc-105 [Source:UniProtKB/Swiss-Prot;Acc:Q09274])

HSP 1 Score: 51.2174 bits (121), Expect = 2.049e-6
Identity = 45/196 (22.96%), Postives = 83/196 (42.35%), Query Frame = 3 
Query:  900 YSG---SYDDCKKIVSQQKYVKYCNCYNSFLPIFKNSSGFPRLCLNASIFSEAEVLKNAKCMINTFRKYAE-SDKARRRFYNRCKMYRPIPCNKVLYKIDHRKEILVDLWSKSTNDRRREIIKTLYLKTFQTNETSLDFVEKVKDNIMQLIINRDNESGDLYKEEREYPFSELLSDVGGLMGLWLGLSVIGLFEIV 1475
            Y+G   S + C +  +Q+  V+ C C +   P+ +      + C       +A  +   +C+ NT     E   K +      C  ++P  C +  Y++ +        W  S + +  E +   +L            +EK + N   + I  +  + +  +E   Y  + +L+D+GGL GLW+G SV+ L EIV
Sbjct:  505 YTGFQYSVEACHRSCAQKVIVEACGCADPMYPVAEMFGNNTKPC-------QAVNMDQRECLRNTTLWLGELYSKGKEAIIPDCYCHQP--CQETNYEVTYSSA----RW-PSGSAKVMECLPGDFL-----------CLEKYRKNAAMVQIFYEELNYETMQESPAYTLTSVLADLGGLTGLWIGASVVSLLEIV 675
[Close]
BLAST of asic vs. Ensembl Celegans
Match: unc-105 (Degenerin-like protein unc-105 [Source:UniProtKB/Swiss-Prot;Acc:Q09274])

HSP 1 Score: 51.2174 bits (121), Expect = 2.049e-6
Identity = 45/196 (22.96%), Postives = 83/196 (42.35%), Query Frame = 3 
Query:  900 YSG---SYDDCKKIVSQQKYVKYCNCYNSFLPIFKNSSGFPRLCLNASIFSEAEVLKNAKCMINTFRKYAE-SDKARRRFYNRCKMYRPIPCNKVLYKIDHRKEILVDLWSKSTNDRRREIIKTLYLKTFQTNETSLDFVEKVKDNIMQLIINRDNESGDLYKEEREYPFSELLSDVGGLMGLWLGLSVIGLFEIV 1475
            Y+G   S + C +  +Q+  V+ C C +   P+ +      + C       +A  +   +C+ NT     E   K +      C  ++P  C +  Y++ +        W  S + +  E +   +L            +EK + N   + I  +  + +  +E   Y  + +L+D+GGL GLW+G SV+ L EIV
Sbjct:  505 YTGFQYSVEACHRSCAQKVIVEACGCADPMYPVAEMFGNNTKPC-------QAVNMDQRECLRNTTLWLGELYSKGKEAIIPDCYCHQP--CQETNYEVTYSSA----RW-PSGSAKVMECLPGDFL-----------CLEKYRKNAAMVQIFYEELNYETMQESPAYTLTSVLADLGGLTGLWIGASVVSLLEIV 675
[Close]
BLAST of asic vs. Ensembl Celegans
Match: unc-105 (Degenerin-like protein unc-105 [Source:UniProtKB/Swiss-Prot;Acc:Q09274])

HSP 1 Score: 50.8322 bits (120), Expect = 2.218e-6
Identity = 45/196 (22.96%), Postives = 83/196 (42.35%), Query Frame = 3 
Query:  900 YSG---SYDDCKKIVSQQKYVKYCNCYNSFLPIFKNSSGFPRLCLNASIFSEAEVLKNAKCMINTFRKYAE-SDKARRRFYNRCKMYRPIPCNKVLYKIDHRKEILVDLWSKSTNDRRREIIKTLYLKTFQTNETSLDFVEKVKDNIMQLIINRDNESGDLYKEEREYPFSELLSDVGGLMGLWLGLSVIGLFEIV 1475
            Y+G   S + C +  +Q+  V+ C C +   P+ +      + C       +A  +   +C+ NT     E   K +      C  ++P  C +  Y++ +        W  S + +  E +   +L            +EK + N   + I  +  + +  +E   Y  + +L+D+GGL GLW+G SV+ L EIV
Sbjct:  485 YTGFQYSVEACHRSCAQKVIVEACGCADPMYPVAEMFGNNTKPC-------QAVNMDQRECLRNTTLWLGELYSKGKEAIIPDCYCHQP--CQETNYEVTYSSA----RW-PSGSAKVMECLPGDFL-----------CLEKYRKNAAMVQIFYEELNYETMQESPAYTLTSVLADLGGLTGLWIGASVVSLLEIV 655
[Close]
BLAST of asic vs. Ensembl Celegans
Match: unc-105 (Degenerin-like protein unc-105 [Source:UniProtKB/Swiss-Prot;Acc:Q09274])

HSP 1 Score: 50.8322 bits (120), Expect = 2.218e-6
Identity = 45/196 (22.96%), Postives = 83/196 (42.35%), Query Frame = 3 
Query:  900 YSG---SYDDCKKIVSQQKYVKYCNCYNSFLPIFKNSSGFPRLCLNASIFSEAEVLKNAKCMINTFRKYAE-SDKARRRFYNRCKMYRPIPCNKVLYKIDHRKEILVDLWSKSTNDRRREIIKTLYLKTFQTNETSLDFVEKVKDNIMQLIINRDNESGDLYKEEREYPFSELLSDVGGLMGLWLGLSVIGLFEIV 1475
            Y+G   S + C +  +Q+  V+ C C +   P+ +      + C       +A  +   +C+ NT     E   K +      C  ++P  C +  Y++ +        W  S + +  E +   +L            +EK + N   + I  +  + +  +E   Y  + +L+D+GGL GLW+G SV+ L EIV
Sbjct:  485 YTGFQYSVEACHRSCAQKVIVEACGCADPMYPVAEMFGNNTKPC-------QAVNMDQRECLRNTTLWLGELYSKGKEAIIPDCYCHQP--CQETNYEVTYSSA----RW-PSGSAKVMECLPGDFL-----------CLEKYRKNAAMVQIFYEELNYETMQESPAYTLTSVLADLGGLTGLWIGASVVSLLEIV 655
[Close]
BLAST of asic vs. Ensembl Celegans
Match: unc-105 (Degenerin-like protein unc-105 [Source:UniProtKB/Swiss-Prot;Acc:Q09274])

HSP 1 Score: 50.8322 bits (120), Expect = 2.442e-6
Identity = 45/196 (22.96%), Postives = 83/196 (42.35%), Query Frame = 3 
Query:  900 YSG---SYDDCKKIVSQQKYVKYCNCYNSFLPIFKNSSGFPRLCLNASIFSEAEVLKNAKCMINTFRKYAE-SDKARRRFYNRCKMYRPIPCNKVLYKIDHRKEILVDLWSKSTNDRRREIIKTLYLKTFQTNETSLDFVEKVKDNIMQLIINRDNESGDLYKEEREYPFSELLSDVGGLMGLWLGLSVIGLFEIV 1475
            Y+G   S + C +  +Q+  V+ C C +   P+ +      + C       +A  +   +C+ NT     E   K +      C  ++P  C +  Y++ +        W  S + +  E +   +L            +EK + N   + I  +  + +  +E   Y  + +L+D+GGL GLW+G SV+ L EIV
Sbjct:  543 YTGFQYSVEACHRSCAQKVIVEACGCADPMYPVAEMFGNNTKPC-------QAVNMDQRECLRNTTLWLGELYSKGKEAIIPDCYCHQP--CQETNYEVTYSSA----RW-PSGSAKVMECLPGDFL-----------CLEKYRKNAAMVQIFYEELNYETMQESPAYTLTSVLADLGGLTGLWIGASVVSLLEIV 713
[Close]
BLAST of asic vs. TrEMBL
Match: S5W2R2 (Asic OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 1024.62 bits (2648), Expect = 0.000e+0
Identity = 494/495 (99.80%), Postives = 494/495 (99.80%), Query Frame = 3 
Query:    3 MIDLIQSSTIHGIGHIFSATNKIFKVLWCILFLVGVIAIIVNIVFISMKFLSNPVIISYTFEHEPFIWPDITFCNPTDPYAFTINSQPYLHWIETLNKTKRVAGKVARQTSMSQLIHSRRENDYELEERTIAMSSADPAKLQATAFQNYLYRIGYIKAHKGLYFSKEFQSSSTKLNEDWKSLFTSQIVQMRNNIPCHTFHLDKSRIVKQKFIKSLLFRFKLNEESYKIFNSSYTFQSMFLYISNKDEIPQSNEIILTPGYNNVVQLTQNRHSYTGLRRTCRNEKFEAELYDSLLQSTEKYSGSYDDCKKIVSQQKYVKYCNCYNSFLPIFKNSSGFPRLCLNASIFSEAEVLKNAKCMINTFRKYAESDKARRRFYNRCKMYRPIPCNKVLYKIDHRKEILVDLWSKSTNDRRREIIKTLYLKTFQTNETSLDFVEKVKDNIMQLIINRDNESGDLYKEEREYPFSELLSDVGGLMGLWLGLSVIGLFEIVEFFY 1487
            MIDLIQSSTIHGIGHIFSATNKIFKVLWCILFLVGVIAIIVNIVFISMKFLSNPVIISYTFEHEPFIWPDITFCNPTDPYAFTINSQPYLHWIETLNKTKRVAGKVARQTSMSQLIHSRRENDYELEERTIAMSSADPAKLQATAFQNYLYRIGYIKAHKGLYFSKEFQSSSTKLNEDWKSLFTSQIVQMRNNIPCHTFHLDKSRIVKQKFIKSLLFRFKLNEESYKIFNSSYTFQSMFLYISNKDEIPQSNEIILTPGYNNVVQLTQNRHSYTGLRRTCRNEKFEAELYDSLLQSTEKYSGSYDDCKKIVSQQKYVKYCNCYNSFLPIFKNSSGFPRLCLNASIFSEAEVLKNAKCMINTFRKYAESDKARRRFYNRCKMYRPIPCNKVLYKIDHRKEILVDLWSKSTNDRRREIIKTLYLKTFQTNETSLDFVEKVKDNIMQLIINRDNESGDLYKEEREYPFSELLSDVGGLMGLWLGLSVIGLFEIVEF Y
Sbjct:    1 MIDLIQSSTIHGIGHIFSATNKIFKVLWCILFLVGVIAIIVNIVFISMKFLSNPVIISYTFEHEPFIWPDITFCNPTDPYAFTINSQPYLHWIETLNKTKRVAGKVARQTSMSQLIHSRRENDYELEERTIAMSSADPAKLQATAFQNYLYRIGYIKAHKGLYFSKEFQSSSTKLNEDWKSLFTSQIVQMRNNIPCHTFHLDKSRIVKQKFIKSLLFRFKLNEESYKIFNSSYTFQSMFLYISNKDEIPQSNEIILTPGYNNVVQLTQNRHSYTGLRRTCRNEKFEAELYDSLLQSTEKYSGSYDDCKKIVSQQKYVKYCNCYNSFLPIFKNSSGFPRLCLNASIFSEAEVLKNAKCMINTFRKYAESDKARRRFYNRCKMYRPIPCNKVLYKIDHRKEILVDLWSKSTNDRRREIIKTLYLKTFQTNETSLDFVEKVKDNIMQLIINRDNESGDLYKEEREYPFSELLSDVGGLMGLWLGLSVIGLFEIVEFVY 495
[Close]
BLAST of asic vs. TrEMBL
Match: A0A5J4NUF1 (Uncharacterized protein OS=Paragonimus westermani OX=34504 GN=DEA37_0013022 PE=3 SV=1)

HSP 1 Score: 292.738 bits (748), Expect = 1.261e-86
Identity = 173/526 (32.89%), Postives = 275/526 (52.28%), Query Frame = 3 
Query:   12 LIQSSTIHGIGHIFSATNKIFKVLWCILFLVGVIAIIVNIVFISMKFLSNPVIISYTFEHEPFIWPDITFCNPTDPYAFTINSQPYLHWIETLNKTKRVAGKVARQTSMSQLIHSRRENDYELEERTIAMSSADPAKLQATAFQNYLYRIGYIKAHKGLYFSKEFQSSSTKLNEDWKSLFTSQIVQMRNNIPCHTFHLDKS-RIVKQKFIKSLLFRFKLNEESYKIFNSSYTFQSMFLYISNKDEIPQSNEIILTPGYNNVVQLTQNRHSYTGLRRTCRNEKFEAELYDSLLQSTEKYSGSYDDCKKIVSQQKYVKYCNCYNSFL--PIFKNSSGFPR---LCLNASIFSEAEVLKNAKCMINTFRKYAESDKARRRFYNR-CKMYRPIPCNKVLYKI-DHRKEILVDLWSKSTNDRRREIIKTLYLKTFQT----------------------NETSLDFVEKVKDNIMQLIINRDNESGDLYKEEREYPFSELLSDVGGLMGLWLGLSVIGLFEIVEFFYLFLM 1499
            L++ ST+HG+ H+ +A  K+ ++ W  L L G+     N+ FI  ++L+ PV+ SY  E+E FIWPDIT CN   PY+  ++ +    W    N+    A K+   +S+   I S+ +N  E+  + +  S+  P +      + ++  +     ++G+  + E   + T LN   K  F +Q++Q R N+PC+T  L  S   V+   + S+    K N ESY+I NSSY    + L+IS+    P  + I + PGY   + L  +R      R +CR + +  E++D  L +  + +GS   C +IVSQ  Y+  C+CY+ FL  P+  N   F +   LC N S FS A++ +NA CM+  + +Y  S         R C+ +R   C+ V YK+ D R+  +V+LWS S N+ R   + + +   F +                      N++    ++ ++DN   L +NR +E G+L +EE EYP SEL+SDVGGLMGLW+G+SVIGLFEIVE     +M
Sbjct:   30 LLEHSTVHGLSHVSTAATKLGRITWFCLLLAGIAGFFTNLSFIIDRYLTRPVLTSYISEYEGFIWPDITLCNAMAPYSLHLHGR-IPKWQALRNQASAFAQKL--NSSLFASIDSQDQN--EIAIQALMYSTLSPPEYGVGEPEEFIQFVATDVGYQGIILTVEISGNMTHLNPPLKKYFHTQVLQKRYNVPCYTLQLRHSLTAVQSNQVNSIGLGVKFNVESYRIINSSYASPYIDLFISHPGHAPHDDPIEMLPGYTLSLSLRMSRLRREPARLSCRTDFYTTEVFDPDLVTKRRVNGSATFCHRIVSQHLYLNSCHCYSPFLPYPVVYNHKLFSKMAILCFNMSRFSVAQINRNADCMLRIYERYQLSSVYNSVPEARACEQFRKPLCDDVEYKLSDIRRTAMVELWSNSYNEARIAFLTSSFQNLFSSDIPPEQLVSWLDSDTKDDNTKDNDSMPKILKYMRDNFGLLSVNRKSELGELVREELEYPLSELMSDVGGLMGLWIGISVIGLFEIVELCGFAIM 550
[Close]
BLAST of asic vs. TrEMBL
Match: A0A504YRR8 (Degenerin unc-8 OS=Fasciola gigantica OX=46835 GN=FGIG_05554 PE=3 SV=1)

HSP 1 Score: 276.944 bits (707), Expect = 2.467e-80
Identity = 162/527 (30.74%), Postives = 270/527 (51.23%), Query Frame = 3 
Query:   12 LIQSSTIHGIGHIFSATNKIFKVLWCILFLVGVIAIIVNIVFISMKFLSNPVIISYTFEHEPFIWPDITFCNPTDPYAFTINSQPYLHWIETLNKTKRVAGKVARQTSMSQLIHSRRENDYELEERTIAMSSADPAKLQATAFQNYLYRIGYIKAHKGLYFSKEFQSSSTKLNEDWKSLFTSQIVQMRNNIPCHTFHLDKSRIVKQ-KFIKSLLFRFKLNEESYKIFNSSYTFQSMFLYISNKDEIPQSNEIILTPGYNNVVQLTQNRHSYTGLRRTCRNEKFEAELYDSLLQSTEKYSGSYDDCKKIVSQQKYVKYCNCYNSFL--PIFKNSSGF---PRLCLNASIFSEAEVLKNAKCMINTFRKYAES----DKARRRFYNRCKMYRPI-PCNKVLYKIDH-RKEILVDLWSKSTNDRRREIIKTLYLKTF---------------QTNETSLDFVEKVKDNIMQLIINRDNESGDLYKEEREYPFSELLSDVGGLMGLWLGLSVIGLFEIVEFFYLFLMGIFS 1511
            L++ ST+HG+ H+ +A+ +I + +W IL++ GV     N+ FI  ++++ PV+ SY  +HE FIWPDIT CNP  PY   +N++      E  N   ++A  V+R  S +           E+  + +  S+  P +  A      ++ +   K   G++ + E  ++ T L+      F  Q++Q R NIPC+T  LD+    ++    K +    K N +S  I NSSY   ++ L+IS    +P+   + +  GY++ V +T  R +    R  CR E+F  +++D+ L++  +  GS D C K++SQ+ Y+ +C CY+ FL  P+          P LC N S F+ + + +NA+CM   + ++ E     +     F   C+ +R   PC  + Y ++  R+  +++ W+ + N+ R   + + +   F                 N +SL F   +++N   + I R    G L  EE EYP SELLSDVGGLMGLW+G+SVIGLFE+VE F    + + S
Sbjct:   34 LLEHSTVHGLSHVSTASTRIGRSVWLILWMAGVAGFFTNLSFIVSRYMTRPVLTSYKHDHELFIWPDITLCNPMAPYPVHLNNRS-----EKWNLLHQLATAVSRNISGNLFATIDEAEQEEVTVQALIHSTVSPMEFGANDPHELVHFVAVDKGQTGIHLTIEMDATFTNLDIPKHRYFHVQVLQKRYNIPCYTLRLDQVLNEEECASTKQVSLGLKFNHDSNLIINSSYAPFNIDLFISLPGHMPEDEPMEILSGYSHKVTVTMGRFTRERTRLPCRTEQFVTQVFDADLKTQREVVGSADFCLKLLSQRLYIDHCGCYSPFLPYPVMGQDHPLYQHPVLCFNMSHFNASGIDRNARCMYEVYTQFKEDFIYMNLPEAGF---CETFRATPPCESINYVLESPRRTPIIEFWADTVNEARSAFVTSTFESVFGQDLPEERLKQMVNNSGNTSSLLFY--MRNNFGLVKITRKLPRGTLTHEELEYPLSELLSDVGGLMGLWVGISVIGLFEVVELFAFVGLTVIS 550
[Close]
BLAST of asic vs. TrEMBL
Match: A0A183A5V1 (Uncharacterized protein OS=Echinostoma caproni OX=27848 GN=ECPE_LOCUS2336 PE=3 SV=1)

HSP 1 Score: 275.018 bits (702), Expect = 8.867e-80
Identity = 162/524 (30.92%), Postives = 267/524 (50.95%), Query Frame = 3 
Query:   12 LIQSSTIHGIGHIFSATNKIFKVLWCILFLVGVIAIIVNIVFISMKFLSNPVIISYTFEHEPFIWPDITFCNPTDPYAFTINSQPYLHWIETLNKTKRVAGKVARQTSMSQLIHSRRENDYELEERTIAMSSADPAKLQATAFQNYLYRIGYIKAHKGLYFSKEFQSSSTKLNEDWKSLFTSQIVQMRNNIPCHTFHLDKSRIVKQKFIKS---LLFRFKLNEESYKIFNSSYTFQSMFLYISNKDEIPQSNEIILTPGYNNVVQLTQNRHSYTGLRRTCRNEKFEAELYDSLLQSTEKYSGSYDDCKKIVSQQKYVKYCNCYNSFLPIFKNSS-----GFPRLCLNASIFSEAEVLKNAKCMINTFRKYAE-SDKARRRFYNRCKMYRPI-PCNKVLYKIDH-RKEILVDLWSKSTNDRRREIIKTLYLKTFQTN-------------ETSLDFVEKVKDNIMQLIINRDNESGDLYKEEREYPFSELLSDVGGLMGLWLGLSVIGLFEIVEFFYLFLMGIFS 1511
            L++ ST+HG+ H+ +A+++I + +W IL+L GV     N+ FI  ++++ PV+ SY  +HE FIWPDIT CNP  PY   + ++      E  N+ +  A +VA+  S             E+  + +  S+  P +      Q  +  +   K   G++ + E  S+ T L+      F +Q++Q R+NIPC+T  L  + ++ Q+   S   +    K N +S+ I NSSY  +++ L+IS     P+   + L  GY + V ++  R      R  CR ++F A+++D+ L++  +  GS D C K+VSQ+ Y+  C CY+ FLP           G P LC N S F+   + +NAKCM + + +Y + S          C+ +R   PC    Y  +  R+  +++LWS + N+ R   + + +   F  +               + +    +++N   + I+R    G L  EE EYP SELLSD+GGLMGLW+G+SVIGLFE+VE      + + S
Sbjct:   33 LLEHSTVHGLSHVSTASSRIGRSIWLILWLAGVAGFFTNLSFIVSRYMTRPVLTSYKHDHESFIWPDITLCNPMAPYPVHLRNR-----TEKWNELRLRATRVAKNISEDLFAAIDDAEQLEIAIQALLYSTISPEQFGVGEPQELIQFVAADKGRSGIHLTVEMYSTFTDLDAPKTQYFHAQMLQKRHNIPCYTLQL--AHVLSQEDCLSTNQVSLGLKFNHDSFLIINSSYAPRNIDLFISLPGHFPEDESMELLSGYTHKVSVSMTRFIREPNRLPCRTDEFVAQMFDANLKTRREIVGSADFCHKLVSQRLYINNCGCYSPFLPYPVVDEHLLVHGQPVLCFNMSHFNITSIDQNAKCMYDVYTQYHDHSVYMNLPEAQYCETFRSTPPCESTSYMPESLRRTPIIELWSDTINEGRTAFLTSTFESVFGPDLPEERIRQLLNNSGNNSNMFTYMRNNFGMVTISRKFPRGTLTHEELEYPLSELLSDLGGLMGLWIGISVIGLFEVVELLAFVSLSMIS 549
[Close]
BLAST of asic vs. TrEMBL
Match: A0A4E0RSD9 (Degenerin unc-8 OS=Fasciola hepatica OX=6192 GN=D915_000009 PE=3 SV=1)

HSP 1 Score: 275.404 bits (703), Expect = 9.545e-80
Identity = 162/529 (30.62%), Postives = 270/529 (51.04%), Query Frame = 3 
Query:   12 LIQSSTIHGIGHIFSATNKIFKVLWCILFLVGVIAIIVNIVFISMKFLSNPVIISYTFEHEPFIWPDITFCNPTDPYAFTINSQPYLHWIETLNKTKRVAGKVARQTSMSQLIHSRRENDYELEERTIAMSSADPAKLQATAFQNYLYRIGYIKAHKGLYFSKEFQSSSTKLNEDWKSLFTSQIVQMRNNIPCHTFHLDKSRIVKQ-KFIKSLLFRFKLNEESYKIFNSSYTFQSMFLYISNKDEIPQSNEIILTPGYNNVVQLTQNRHSYTGLRRTCRNEKFEAELYDSLLQSTEKYSGSYDDCKKIVSQQKYVKYCNCYNSFL--PIFKNSSGF---PRLCLNASIFSEAEVLKNAKCMINTFRKYAES------DKARRRFYNRCKMYRPI-PCNKVLYKIDH-RKEILVDLWSKSTNDRRREIIKTLYLKTF---------------QTNETSLDFVEKVKDNIMQLIINRDNESGDLYKEEREYPFSELLSDVGGLMGLWLGLSVIGLFEIVEFFYLFLMGIFS 1511
            L++ ST+HG+ H+ +A  +I + +W IL++ GV     N+ FI  ++++ PV+ SY  +HE FIWPDIT CNP  PY   +N++      E  N   ++A  V+R  S +           E+  + +  S+  P +  A      ++ +   K   G++ + E  ++ T L+      F  Q++Q R NIPC+T  LD+    ++    K +    K N +S  I NSSY   ++ L+IS    +P+   + +  GY++ V +T  R +    R  CR E+F  +++D+ L++  +  GS D C K++SQ+ Y+ +C CY+ FL  P+          P LC N S F+ + + +NA+CM + + ++ E        +A       C+ +R   PC  + Y ++  R+  +++ W+ + N+ R   + + +   F                 N +SL F   +++N   + I R    G L  EE EYP SELLSDVGGLMGLW+G+SVIGLFE+VE F    + + S
Sbjct:   34 LLEHSTVHGLSHVSTAGTRIGRSVWLILWMAGVAGFFTNLSFIVSRYMTRPVLTSYKHDHELFIWPDITLCNPMAPYPVHLNNRS-----EKWNLLHQLATAVSRNISGNLFATIDEAEQEEVTVQALIHSTVSPMEFGANDPHELVHFVAVDKGQTGIHLTIEMDATFTNLDIPKHRYFHVQVLQKRYNIPCYTLRLDQVLNEEECASTKQVSLGLKFNHDSNLIINSSYAPFNIDLFISLPGHMPEDEPMEILSGYSHKVTVTMGRFTRERTRLPCRTEQFVTQVFDADLKTQREVVGSADFCLKLLSQRLYIDHCGCYSPFLPYPVMGQDHPLYQQPVLCFNMSHFNASGIDRNARCMYDVYTQFKEDFVYMNLPEA-----GYCETFRATPPCESINYVLESPRRTPIIEFWADTVNEARSAFVTSTFESVFGQDLPEERLKQMVNNSGNTSSLLFY--MRNNFGLVKITRKLPRGTLTHEELEYPLSELLSDVGGLMGLWVGISVIGLFEVVELFAFVGLTVIS 550
[Close]
BLAST of asic vs. Ensembl Nematostella
Match: EDO34532 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SP23])

HSP 1 Score: 47.7506 bits (112), Expect = 7.311e-6
Identity = 33/130 (25.38%), Postives = 62/130 (47.69%), Query Frame = 3 
Query:    9 DLIQSSTIHGIGHIFSATNKIFKVLWCILFLVGVIAIIVNIVFIS----MKFLSNPVI--ISYTFEHEPFIWPDITFCNPTDPYAFTINSQPYLHWIETLNKTKRVAGKVARQTSMSQLIHSRRENDYEL 380
            D   S+T HGIG +F+A + + + LW    L+G + +   ++F+     +++L  PV+  +  ++E E  ++P +T CN                    LN  K    KVA+  S+  L+ + +E D ++
Sbjct:   65 DFAASTTAHGIGKVFAADSMVRRALW----LLGCLTVYAVMIFMCAQLLVRYLEKPVVSRVEVSYE-ESLVFPAVTICN--------------------LNMLKH--SKVAKNPSIQSLMTNMKEKDEKM 167
[Close]
BLAST of asic vs. Ensembl Nematostella
Match: EDO36191 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJB5])

HSP 1 Score: 47.7506 bits (112), Expect = 8.328e-6
Identity = 50/187 (26.74%), Postives = 73/187 (39.04%), Query Frame = 3 
Query:  984 PIFKNSSGFPRLCLNASIF---------SEAEVLKNAKCMINTFRKYAESDKARRRFYNRCKMYRPIPCNKVLYKIDHRKEILVDLWSKSTNDRRREIIKTLYLKTFQ--TNETSLDFVEKVKDNIMQLIINRDNESGDLYKEE--RE-------YPFSELLSDVGGLMGLWLGLSVIGLFEIVEFF 1484
            P    S+G  + C+++ +          +E +     KC+ N  +KY             C    P PC    +    R+ I    WS S            Y KTFQ    ++   F  K+ D     I+ ++     LY EE  RE       YP   LL DVGG +GLW+G+SVI   E ++  
Sbjct:  291 PGVSASAGIRQGCMSSCLANNQFKVCNCTEGKFRAKVKCLNNISKKYENGSLG-------CSKSCPQPCTHYSF----RRTISQTQWSDS------------YEKTFQRLVRKSDRGFANKMND---ASILRKNFLRVKLYYEELNRETITYSLSYPVENLLGDVGGQLGLWIGVSVITCAEFLKLL 451
[Close]
BLAST of asic vs. Planmine SMEST
Match: SMESG000011523.1 (SMESG000011523.1)

HSP 1 Score: 1089.72 bits (2817), Expect = 0.000e+0
Identity = 526/526 (100.00%), Postives = 526/526 (100.00%), Query Frame = 3 
Query:    3 MIDLIQSSTIHGIGHIFSATNKIFKVLWCILFLVGVIAIIVNIVFISMKFLSNPVIISYTFEHEPFIWPDITFCNPTDPYAFTINSQPYLHWIETLNKTKRVAGKVARQTSMSQLIHSRRENDYELEERTIAMSSADPAKLQATAFQNYLYRIGYIKAHKGLYFSKEFQSSSTKLNEDWKSLFTSQIVQMRNNIPCHTFHLDKSRIVKQKFIKSLLFRFKLNEESYKIFNSSYTFQSMFLYISNKDEIPQSNEIILTPGYNNVVQLTQNRHSYTGLRRTCRNEKFEAELYDSLLQSTEKYSGSYDDCKKIVSQQKYVKYCNCYNSFLPIFKNSSGFPRLCLNASIFSEAEVLKNAKCMINTFRKYAESDKARRRFYNRCKMYRPIPCNKVLYKIDHRKEILVDLWSKSTNDRRREIIKTLYLKTFQTNETSLDFVEKVKDNIMQLIINRDNESGDLYKEEREYPFSELLSDVGGLMGLWLGLSVIGLFEIVEFFYLFLMGIFSLGKKDDLLTDEMEQKDQVVQSSI 1580
            MIDLIQSSTIHGIGHIFSATNKIFKVLWCILFLVGVIAIIVNIVFISMKFLSNPVIISYTFEHEPFIWPDITFCNPTDPYAFTINSQPYLHWIETLNKTKRVAGKVARQTSMSQLIHSRRENDYELEERTIAMSSADPAKLQATAFQNYLYRIGYIKAHKGLYFSKEFQSSSTKLNEDWKSLFTSQIVQMRNNIPCHTFHLDKSRIVKQKFIKSLLFRFKLNEESYKIFNSSYTFQSMFLYISNKDEIPQSNEIILTPGYNNVVQLTQNRHSYTGLRRTCRNEKFEAELYDSLLQSTEKYSGSYDDCKKIVSQQKYVKYCNCYNSFLPIFKNSSGFPRLCLNASIFSEAEVLKNAKCMINTFRKYAESDKARRRFYNRCKMYRPIPCNKVLYKIDHRKEILVDLWSKSTNDRRREIIKTLYLKTFQTNETSLDFVEKVKDNIMQLIINRDNESGDLYKEEREYPFSELLSDVGGLMGLWLGLSVIGLFEIVEFFYLFLMGIFSLGKKDDLLTDEMEQKDQVVQSSI
Sbjct:    1 MIDLIQSSTIHGIGHIFSATNKIFKVLWCILFLVGVIAIIVNIVFISMKFLSNPVIISYTFEHEPFIWPDITFCNPTDPYAFTINSQPYLHWIETLNKTKRVAGKVARQTSMSQLIHSRRENDYELEERTIAMSSADPAKLQATAFQNYLYRIGYIKAHKGLYFSKEFQSSSTKLNEDWKSLFTSQIVQMRNNIPCHTFHLDKSRIVKQKFIKSLLFRFKLNEESYKIFNSSYTFQSMFLYISNKDEIPQSNEIILTPGYNNVVQLTQNRHSYTGLRRTCRNEKFEAELYDSLLQSTEKYSGSYDDCKKIVSQQKYVKYCNCYNSFLPIFKNSSGFPRLCLNASIFSEAEVLKNAKCMINTFRKYAESDKARRRFYNRCKMYRPIPCNKVLYKIDHRKEILVDLWSKSTNDRRREIIKTLYLKTFQTNETSLDFVEKVKDNIMQLIINRDNESGDLYKEEREYPFSELLSDVGGLMGLWLGLSVIGLFEIVEFFYLFLMGIFSLGKKDDLLTDEMEQKDQVVQSSI 526
[Close]
BLAST of asic vs. Planmine SMEST
Match: SMESG000020604.1 (SMESG000020604.1)

HSP 1 Score: 749.199 bits (1933), Expect = 0.000e+0
Identity = 358/527 (67.93%), Postives = 446/527 (84.63%), Query Frame = 3 
Query:    3 MIDLIQSSTIHGIGHIFSATNKIFKVLWCILFLVGVIAIIVNIVFISMKFLSNPVIISYTFEHEPFIWPDITFCNPTDPYAFTINSQPYLHWIETLNKTKRVAGKVARQTSMSQLIHSRRENDYELEERTIAMSSADPAKLQATAFQNYLYRIGYIKAHKGLYFSKEFQSSS-TKLNEDWKSLFTSQIVQMRNNIPCHTFHLDKSRIVKQKFIKSLLFRFKLNEESYKIFNSSYTFQSMFLYISNKDEIPQSNEIILTPGYNNVVQLTQNRHSYTGLRRTCRNEKFEAELYDSLLQSTEKYSGSYDDCKKIVSQQKYVKYCNCYNSFLPIFKNSSGFPRLCLNASIFSEAEVLKNAKCMINTFRKYAESDKARRRFYNRCKMYRPIPCNKVLYKIDHRKEILVDLWSKSTNDRRREIIKTLYLKTFQTNETSLDFVEKVKDNIMQLIINRDNESGDLYKEEREYPFSELLSDVGGLMGLWLGLSVIGLFEIVEFFYLFLMGIFSLGKKDDLLTDEMEQKDQVVQSSI 1580
            MIDLIQSSTIHGIGHI+SA  K+ K LWCILFL GV+ IIVNIVF+SMKF SNPVIISYTFE+EPFIWPDITFCNPTDPYAF I+S+PYL+WI+TLN+TK +A +V R++ +SQ+IHS+ +ND+ELEERTIAMS+ADP KL A  FQNYL RIGY+KAH+GLYFSKE+QSSS +K +E+ K LFTSQ +Q+RNNIPCHTFHLDKSR + Q+ I+SL+FRFK NE+SYK+FNSSYTFQS+FLYI+NK+EIP  NEIILTPGYNN+VQLTQNR+ + G+RR CR ++++ ELY++LLQSTE + G++DDC +I SQ+ YV+ C+CY+ FLPI+KN SGFPRLCLNASIFS +E+L N KC+I+T+  +  + K + ++Y+ C+ Y+PIPC ++ YKIDHRKE+LVDLWSKS NDRR  I+K +Y   F+TNETS DFV KVKDNIMQLIINRD+E GDL+KEEREYPF+ELLSD+GGLMGLWLGLSV+GLFEIVEF YLFL G+F+ G K   L + +   +  + ++I
Sbjct:    1 MIDLIQSSTIHGIGHIYSAPGKVSKGLWCILFLFGVVGIIVNIVFVSMKFFSNPVIISYTFEYEPFIWPDITFCNPTDPYAFEIDSEPYLYWIKTLNQTKPIAERVFRESEISQVIHSQNDNDFELEERTIAMSTADPEKLGANGFQNYLTRIGYVKAHRGLYFSKEYQSSSPSKFSENLKPLFTSQTIQIRNNIPCHTFHLDKSRFLSQRRIRSLIFRFKFNEKSYKMFNSSYTFQSIFLYINNKNEIPIENEIILTPGYNNIVQLTQNRYVHNGMRRPCRTKEYKVELYEALLQSTETFFGNFDDCNQITSQRMYVENCHCYSPFLPIYKNESGFPRLCLNASIFSLSEILNNTKCLIDTYNDFQSAPKIKAKYYSECREYKPIPCERISYKIDHRKEMLVDLWSKSANDRRLGIVKQIYYHVFETNETSSDFVHKVKDNIMQLIINRDSEYGDLFKEEREYPFAELLSDIGGLMGLWLGLSVVGLFEIVEFLYLFLKGVFNFGHKMIPLANHVAGAEHEMINAI 527
[Close]
BLAST of asic vs. Planmine SMEST
Match: SMESG000069054.1 (SMESG000069054.1)

HSP 1 Score: 572.392 bits (1474), Expect = 0.000e+0
Identity = 267/498 (53.61%), Postives = 378/498 (75.90%), Query Frame = 3 
Query:    3 MIDLIQSSTIHGIGHIFSATNKIFKVLWCILFLVGVIAIIVNIVFISMKFLSNPVIISYTFEHEPFIWPDITFCNPTDPYAFTINSQPYLHWIETLNKTKRVAGKVARQTSMSQLIHSRRENDYELEERTIAMSSADPAKLQATAFQNYLYRIGYIKAHKGLYFSKEFQSSSTK-LNEDWKSLFTSQIVQMRNNIPCHTFHLDKSRIVKQKFIKSLLFRFKLNEESYKIFNSSYTFQSMFLYISNKDEIPQSNEIILTPGYNNVVQLTQNRHSYTGLRRTCRNEKFEAELYDSLLQSTEKYSGSYDDCKKIVSQQKYVKYCNCYNSFLPIFKNSSGFPRLCLNASIFSEAEVLKNAKCMINTFRKYAESDKARRRFYNRCKMYRPIPCNKVLYKIDHRKEILVDLWSKSTNDRRREIIKTLYLKTFQTNETSLDFVEKVKDNIMQLIINRDNESGDLYKEEREYPFSELLSDVGGLMGLWLGLSVIGLFEIVEFFYLF 1493
            MI+L++SSTIHGI HI+SA  K+ K LWC+LF+ G+I IIVNI F+S+++ S PV+ISYTFEHEPF+WPDITFCNPT P+     S+ Y +W++  N+++ V   + ++T + Q+I   +E D+ELEERTIAM+S++P KL A  F+N++  +GY + H G+YF+K+ Q+++ K    D K LF++QIVQ++NNIPCHTFH+ KS I+    ++SL+F  + N +SY+IFNSSYT +S+FLYISN+DEI Q   I L+PG+NN++ L+QNRH Y GLRR CR++ F+ E+YD+L Q+ + + GSY+DCK+IVSQ+ +V  C CY+ FLPIFKN +GFPRLCLNA+ FS+ ++L+NAKCM+N +  + +S   R+ + N+C +++   C+ + Y++D RK++LV+LWSK  N +R   IK ++   F  NE+  DF E ++DNI+ LII R  E  DL+KEEREYPFSELLSD+GGLMGLWLG+SV+GLFEI+EFFYLF
Sbjct:    1 MIELVKSSTIHGINHIYSANGKLAKFLWCVLFIFGIIGIIVNICFVSIRYFSYPVLISYTFEHEPFVWPDITFCNPTAPFYLDRKSKAYKYWMQINNQSRDVVKMLVKETKLFQIIRESKETDFELEERTIAMASSNPVKLGADLFENHVKFVGYTRPHSGIYFNKDIQNNNPKTFPGDLKPLFSTQIVQIQNNIPCHTFHMHKSNILNPNSVQSLVFGLRFNYDSYEIFNSSYTTRSIFLYISNRDEIQQDQNIFLSPGFNNILSLSQNRHHYNGLRRKCRHKTFKFEVYDALFQNVKTFEGSYEDCKQIVSQRLFVDKCKCYSPFLPIFKNQTGFPRLCLNATFFSKTKLLENAKCMVNVYENFKKSGNFRKHYNNQCLIFKLHKCDLLSYQMDLRKDMLVELWSKVYNGKRLNSIKFMHSYYFGKNESKKDFNEVMRDNIVDLIIERKFEYSDLFKEEREYPFSELLSDIGGLMGLWLGMSVVGLFEILEFFYLF 498
[Close]
BLAST of asic vs. Planmine SMEST
Match: SMESG000017678.1 (SMESG000017678.1)

HSP 1 Score: 553.132 bits (1424), Expect = 0.000e+0
Identity = 261/518 (50.39%), Postives = 362/518 (69.88%), Query Frame = 3 
Query:    3 MIDLIQSSTIHGIGHIFSATNKIFKVLWCILFLVGVIAIIVNIVFISMKFLSNPVIISYTFEHEPFIWPDITFCNPTDPYAFTINSQPYLHWIETLNKTKRVAGKVARQTSMSQLIHSRRENDYELEERTIAMSSADPAKLQATAFQNYLYRIGYIKAHKGLYFSKEFQS-SSTKLNEDWKSLFTSQIVQMRNNIPCHTFHLDKSRIVKQKFIKSLLFRFKLNEESYKIFNSSYTFQSMFLYISNKDEIPQSNEIILTPGYNNVVQLTQNRHSYTGLRRTCRNEKFEAELYDSLLQSTEKYSGSYDDCKKIVSQQKYVKYCNCYNSFLPIFKNSSGFPRLCLNASIFSEAEVLKNAKCMINTFRKYAESDKARRRFYNRCKMYRPIPCNKVLYKIDHRKEILVDLWSKSTNDRRREIIKTLYLKTFQTNETSLDFVEKVKDNIMQLIINRDNESGDLYKEEREYPFSELLSDVGGLMGLWLGLSVIGLFEIVEFFYLFLMGIFSLGKKDDLLTDEMEQ 1553
            MI+++QSSTIHG+ HI  A ++I KVLW  LF+ G+I I VNIVF+ +K+ SNPV+IS+  +HEPFIWPD+TFC PT PY F  NSQ Y HW     +T+R+  ++A +T + ++I+ +R  DYELEERTIAMSSADP KL+   F+ ++  I + K  +G+Y+  +    + T   ED K LFT+ +VQ+RNNIPC TFH+DKS+ + Q  IKS+ F  K N ESY +FNSSY  +S+FLYI+N++ IP  NEI+L PG+NN+V L+Q+R+ Y G+ R CRN+ FE ELYD LLQST  + G YDDCKK+ SQ+ +V  C CY+ FLPI+KN +G PR+CLNA+ +SE E+++NAKCM + + K+      R  +  +C+ YR I CN+V YKI+  KE+ V+ WS  TN RR E++K +     +  +   ++ E+++DN + + INR+ + GDLYKEE EYPFSELLSD+GGLMGLWLG+SV+GLFEI E  YL+L  +     K     ++ EQ
Sbjct:    1 MIEILQSSTIHGVSHIHGAKSQITKVLWIFLFIFGIIGIFVNIVFVIIKYFSNPVLISHKLDHEPFIWPDVTFCKPTAPYYFGENSQAYTHWSHVFWRTRRIVERLANETEVFKIINGKRNTDYELEERTIAMSSADPYKLKTNDFRYHIMAIYFNKMQRGIYYHIDNSGIAVTSFAEDLKPLFTAPLVQIRNNIPCFTFHIDKSKFLNQNQIKSISFYLKFNLESYLLFNSSYLHRSVFLYITNRNGIPHKNEILLAPGFNNIVSLSQSRYEYRGVLRKCRNKIFETELYDGLLQSTSTFEGHYDDCKKVESQKLFVGICKCYSPFLPIYKNETGPPRICLNATFYSEDEIVRNAKCMTDVYTKFQSYKAFRNHYRLKCQDYRFIKCNEVKYKIEKDKELFVEFWSGLTNQRRNELLKKVSYYLMEKFDIK-NYFERMRDNFIGITINREFQKGDLYKEEYEYPFSELLSDIGGLMGLWLGMSVVGLFEIFELMYLYLKNLCYQTSKQQSNMEKFEQ 517
[Close]
BLAST of asic vs. Planmine SMEST
Match: SMESG000069546.1 (SMESG000069546.1)

HSP 1 Score: 521.931 bits (1343), Expect = 0.000e+0
Identity = 253/503 (50.30%), Postives = 351/503 (69.78%), Query Frame = 3 
Query:    3 MIDLIQSSTIHGIGHIFSATNKIFKVLWCILFLVGVIAIIVNIVFISMKFLSNPVIISYTFEHEPFIWPDITFCNPTDPYAFTINSQPYLHWIETLNKTKRVAGKVARQTSMSQLIHSRRENDYELEERTIAMSSADPAKLQATAFQNYLYRIGY--IKAHKGLYFSKEFQSSSTKLNEDWKSLFTSQIVQMRNNIPCHTFHLDKSRIVKQKFIKSLLFRFKLNEESYKIFNSSYTFQSMFLYISNKDEIPQSNEIILTPGYNNVVQLTQNRHSYTGLRRTCRNEKFEAELYDSLLQSTEKYSGSYDDCKKIVSQQKYVKYCNCYNSFLPIFKNSSGFPRLCLNASIFSEAEVLKNAKCMINTFRKYAESDKARRRFYNRCKMYRPIPCNKVLYKIDHRKEILVDLWSKSTNDRRREIIKTLYLKTFQTNETSLDFVEKVKDNIMQLIINRDNESGDLYKEEREYPFSELLSDVGGLMGLWLGLSVIGLFEIVEFFYLFLMGI 1505
            MI+++QSSTIHG+ HI  A ++I K+LW ILF++G+I I VNIVF+ M++ SNPV+IS   +HEPFIWPDITFC PT PY F  NSQPY HW E   +T+R+  +++ +T   ++++ +R  DYELEERTIAMSSADP KL+   F  ++  I +  I+ +       EF  +    +ED K LFT+ +VQ++NNIPC TFH++KS+ + Q  I S+ F    N +SY +FNSS+  +S+FLYI+N++ IPQ  E++L PG+NN+V L+QNR  Y G++R CRN+ ++ ELYD+LLQST  + G Y DC K+ SQ+  V  C CYN FLPI+KN +G PR+CLNA+ +SE E+LKNAKCM+N  RK+      RR F  +C+ Y+ I CN+V YKI+  K +  +L S  T  RRR++IK  + K FQ  +   DF E+++DN + + I R+   GDLYKEE EYPFS+LLSD+GGLMGLWLG+SV+GLFEI E  Y++   +
Sbjct:    1 MIEILQSSTIHGVSHIHGAKSRITKMLWIILFILGLIGIFVNIVFVIMRYFSNPVLISRNLDHEPFIWPDITFCKPTAPYYFVENSQPYNHWTEVFRRTRRIVERLSNETEFFKIMNGKRNTDYELEERTIAMSSADPYKLKMDNFSYHIMLIVFNRIRTYTNYISDNEFFEN---FHEDLKPLFTAPLVQIQNNIPCFTFHINKSKSLHQDNITSIRFHLNFNIKSYMLFNSSFLHRSVFLYITNRNGIPQKYEMLLEPGFNNIVSLSQNRFEYRGVQRKCRNKTYKVELYDALLQSTSIFEGYYADCMKVESQKLCVSNCKCYNPFLPIYKNETGSPRICLNATFYSEEEILKNAKCMVNRLRKFKSFFLYRRFFNPKCQDYQLIKCNEVKYKIEKEKLLFAELSSGFTTQRRRKVIKG-FSKWFQRIDNRSDF-ERIRDNYIVITIKREFPKGDLYKEEYEYPFSQLLSDIGGLMGLWLGMSVVGLFEIFEIIYMYFTNL 498
The following BLAST results are available for this feature:
BLAST of asic vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of asic vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
unc-1052.049e-622.96Degenerin-like protein unc-105 [Source:UniProtKB/... [more]
unc-1052.049e-622.96Degenerin-like protein unc-105 [Source:UniProtKB/... [more]
unc-1052.218e-622.96Degenerin-like protein unc-105 [Source:UniProtKB/... [more]
unc-1052.218e-622.96Degenerin-like protein unc-105 [Source:UniProtKB/... [more]
unc-1052.442e-622.96Degenerin-like protein unc-105 [Source:UniProtKB/... [more]
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BLAST of asic vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of asic vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of asic vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of asic vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of asic vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of asic vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
S5W2R20.000e+099.80Asic OS=Schmidtea mediterranea OX=79327 PE=2 SV=1[more]
A0A5J4NUF11.261e-8632.89Uncharacterized protein OS=Paragonimus westermani ... [more]
A0A504YRR82.467e-8030.74Degenerin unc-8 OS=Fasciola gigantica OX=46835 GN=... [more]
A0A183A5V18.867e-8030.92Uncharacterized protein OS=Echinostoma caproni OX=... [more]
A0A4E0RSD99.545e-8030.62Degenerin unc-8 OS=Fasciola hepatica OX=6192 GN=D9... [more]
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BLAST of asic vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of asic vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of asic vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of asic vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO345327.311e-625.38Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO361918.328e-626.74Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of asic vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of asic vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000011523.10.000e+0100.00SMESG000011523.1[more]
SMESG000020604.10.000e+067.93SMESG000020604.1[more]
SMESG000069054.10.000e+053.61SMESG000069054.1[more]
SMESG000017678.10.000e+050.39SMESG000017678.1[more]
SMESG000069546.10.000e+050.30SMESG000069546.1[more]
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Cross References
External references for this transcript
DatabaseAccession
SmedGD GBrowseSMED30020592
GenBankAGS83418.1
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30020592 ID=SMED30020592|Name=asic|organism=Schmidtea mediterranea sexual|type=transcript|length=1700bp
AAATGATCGACCTGATCCAAAGCAGCACTATCCATGGAATTGGGCACATT
TTTAGTGCAACTAATAAGATTTTCAAGGTATTATGGTGTATTTTATTTTT
AGTTGGTGTCATAGCAATAATTGTGAACATTGTTTTTATTTCAATGAAAT
TTCTCTCAAATCCCGTTATCATTAGCTACACTTTTGAACACGAGCCTTTT
ATTTGGCCGGATATTACGTTTTGTAATCCAACTGACCCTTATGCTTTCAC
GATCAACTCACAGCCGTATTTGCATTGGATTGAAACTTTAAATAAAACAA
AAAGGGTTGCGGGGAAAGTGGCTAGACAAACTTCGATGTCACAACTAATT
CACAGCCGCAGAGAGAATGATTATGAACTTGAAGAAAGAACAATTGCAAT
GTCTTCGGCTGACCCAGCAAAATTGCAGGCAACTGCTTTTCAAAATTATT
TATACAGAATTGGATATATAAAAGCACATAAAGGTTTGTATTTCTCTAAG
GAATTTCAAAGCAGCTCAACAAAATTGAATGAAGATTGGAAATCACTGTT
TACCTCTCAGATCGTACAAATGAGAAACAATATTCCTTGTCACACATTTC
ACTTGGACAAATCCCGAATTGTGAAACAAAAGTTCATCAAATCCCTACTT
TTTCGTTTCAAACTTAACGAAGAAAGTTATAAAATCTTCAATTCGAGCTA
TACCTTTCAGTCTATGTTTCTTTACATTAGCAATAAAGATGAAATACCCC
AATCGAATGAAATAATTTTGACTCCTGGTTATAATAATGTCGTTCAATTA
ACCCAGAATCGTCATTCTTATACCGGTCTTCGGCGAACTTGTCGAAATGA
AAAATTTGAAGCGGAGCTATACGATTCCTTACTTCAATCAACGGAAAAAT
ATTCCGGATCTTATGATGATTGTAAGAAAATTGTCAGTCAACAAAAATAT
GTGAAATATTGCAATTGTTATAATTCATTTCTACCCATTTTTAAAAATTC
AAGCGGCTTTCCGAGGTTGTGTTTAAATGCTTCAATATTTTCGGAAGCTG
AAGTACTGAAAAATGCAAAATGTATGATAAATACATTCAGGAAGTATGCT
GAGTCTGATAAAGCAAGGAGAAGATTTTATAACAGGTGCAAGATGTACAG
ACCAATTCCATGTAATAAAGTCTTGTACAAAATTGATCACAGAAAAGAGA
TCTTAGTTGATTTATGGTCAAAATCGACAAATGATCGACGCCGTGAGATC
ATTAAAACTTTATATTTAAAAACTTTCCAAACGAATGAAACGAGTTTAGA
TTTCGTTGAAAAGGTAAAGGATAATATAATGCAGCTCATCATCAACCGAG
ACAATGAATCTGGGGATCTTTACAAAGAAGAGAGAGAATATCCGTTTTCA
GAGCTGCTATCAGACGTTGGAGGATTAATGGGATTATGGTTAGGGTTAAG
TGTAATCGGTTTGTTTGAAATTGTCGAATTCTTTTACTTATTTTTAATGG
GAATATTTTCGTTGGGTAAAAAAGATGATCTGTTAACAGATGAGATGGAA
CAGAAAGACCAAGTAGTGCAAAGCTCTATCTAAATTATTACTTTTGACAT
TCAATTTTTATTTATATCATAAAAGGTTTTGTTTAACTTTTGTCAAAAAT
ATTTCCTATTTCTACAATAACTAATATTAGAAATAATATCTGTTTATAAA
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protein sequence of SMED30020592-orf-1

>SMED30020592-orf-1 ID=SMED30020592-orf-1|Name=SMED30020592-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=527bp
MIDLIQSSTIHGIGHIFSATNKIFKVLWCILFLVGVIAIIVNIVFISMKF
LSNPVIISYTFEHEPFIWPDITFCNPTDPYAFTINSQPYLHWIETLNKTK
RVAGKVARQTSMSQLIHSRRENDYELEERTIAMSSADPAKLQATAFQNYL
YRIGYIKAHKGLYFSKEFQSSSTKLNEDWKSLFTSQIVQMRNNIPCHTFH
LDKSRIVKQKFIKSLLFRFKLNEESYKIFNSSYTFQSMFLYISNKDEIPQ
SNEIILTPGYNNVVQLTQNRHSYTGLRRTCRNEKFEAELYDSLLQSTEKY
SGSYDDCKKIVSQQKYVKYCNCYNSFLPIFKNSSGFPRLCLNASIFSEAE
VLKNAKCMINTFRKYAESDKARRRFYNRCKMYRPIPCNKVLYKIDHRKEI
LVDLWSKSTNDRRREIIKTLYLKTFQTNETSLDFVEKVKDNIMQLIINRD
NESGDLYKEEREYPFSELLSDVGGLMGLWLGLSVIGLFEIVEFFYLFLMG
IFSLGKKDDLLTDEMEQKDQVVQSSI*
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Aliases
The feature 'asic' has the following synonyms
Synonym
asic
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000143ventral region of the whole animal
Vocabulary: INTERPRO
TermDefinition
IPR001873ENaC
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: biological process
TermDefinition
GO:0006814sodium ion transport
GO:0006810transport
GO:0006811ion transport
GO:0035725sodium ion transmembrane transport
Vocabulary: molecular function
TermDefinition
GO:0005272sodium channel activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001873Epithelial sodium channelPRINTSPR01078AMINACHANNELcoord: 459..473
score: 36.8
coord: 25..42
score: 23.56
coord: 473..489
score: 50.35
coord: 64..80
score: 24.94
coord: 313..330
score: 30.0
IPR001873Epithelial sodium channelPFAMPF00858ASCcoord: 6..493
e-value: 1.5E-46
score: 159.3
IPR001873Epithelial sodium channelPANTHERPTHR11690AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATEDcoord: 7..499
NoneNo IPR availableGENE3DG3DSA:1.10.287.820coord: 272..387
e-value: 9.6E-31
score: 109.1
NoneNo IPR availableGENE3DG3DSA:2.60.470.10coord: 55..461
e-value: 9.6E-31
score: 109.1
NoneNo IPR availableGENE3DG3DSA:1.10.3590.10coord: 77..237
e-value: 9.6E-31
score: 109.1
NoneNo IPR availableGENE3DG3DSA:1.10.287.770coord: 25..491
e-value: 9.6E-31
score: 109.1
NoneNo IPR availablePANTHERPTHR11690:SF222PICKPOCKET 6-RELATEDcoord: 7..499
NoneNo IPR availableTMHMMTMhelixcoord: 26..48
NoneNo IPR availableTMHMMTMhelixcoord: 475..497