Integrator complex subunit 3

Overview


Name	Integrator complex subunit 3
Smed ID	SMED30020591
Length (bp)	3543

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Integrator complex subunit 3 (SMED30020591) t-SNE clustered cells

Violin plots show distribution of expression levels for Integrator complex subunit 3 (SMED30020591) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Integrator complex subunit 3 (SMED30020591) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Integrator complex subunit 3 (SMED30020591) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30020591

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 1

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication	Specimen	Lifecycle	Evidence
X1 cell	SMED30020591	SMESG000033343.1 SMESG000033340.1	SmedASXL_017444	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015

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Homology

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BLAST of Integrator complex subunit 3 vs. Ensembl Human
Match: INTS3 (integrator complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:26153])

HSP 1 Score: 246.899 bits (629), Expect = 8.326e-67
Identity = 136/399 (34.09%), Postives = 222/399 (55.64%), Query Frame = 1

Query:  223 IQLGILYFLLTERSQTQFDFKDLILISRDGVKACSGHLITLISENWNRLNTDVRTNVLSILIDFISFPM--ADSLFMAIFKRMITGDLSQSNLWLIENMLNLIEEHKELLVKDKKLLPMIVYTYLRLIPTHYQFSIAMNTPNNNLARLCRKEIALVMDVIRNNFDECCKQVGRDLLFTLTQVSNIPEFNKLWSEMNSSLEKLSNQYTNIGEVFSMGTNKIVIATAIPFDMENWILWTMRNVHHCSTNPYKRYQDLFNKRFFSTVESQNLRPFLIRYIIRAFYPDNEMIGSTLISRWATISWLIVQASSPTVVANCKLALIYDWLFYDKQYDCIMDIEPAILAIMHNLTKYSHVSITLVDFLVKTANLYFPLVKDQIISCCRFGLNDAFRVSVFRSLAPL 1413
            I LG+   +LTE +Q Q  ++DL L+SRDG+      +  ++ E + +L    RT ++ ++ + +   +  AD + M   K++  GD++  N+WL E++L+++ E +E ++K   L+ M VYTYLRLI  H+  +         L  L +KE+   + ++R  F EC   +GRDL+  L  V+ IPEF  LW ++  + + LS Q+T I ++    T++  +A  +  DME  +L+    V        KRYQD F +++ ST +SQ+LR  LIRYI    +P NE++ S ++ RWA I WL+   +S    +N KLAL YDWLF+    D IM+IEPAIL + H++  +  ++ TL+DF+ +    ++P ++  +       LN      V   LAPL
Sbjct:   89 ICLGLFTLILTEPAQAQKCYRDLALVSRDGMNIVLNKINQILMEKYLKLQDTCRTQLVWLVRELVKSGVLGADGVCMTFMKQIAGGDVTAKNIWLAESVLDILTEQREWVLKSSILIAMAVYTYLRLIVDHHGTA--------QLQALRQKEVDFCISLLRERFMECL-MIGRDLVRLLQNVARIPEFELLWKDIIHNPQALSPQFTGILQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRF---GQQKRYQDWFQRQYLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFSPDKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPNFYPPLEGHVRQGVFSSLNHIVEKRVLAHLAPL 475

HSP 2 Score: 179.874 bits (455), Expect = 2.923e-45
Identity = 129/385 (33.51%), Postives = 222/385 (57.66%), Query Frame = 1

Query: 2062 EKMEKVVIAILNDDNFDDLGIAGKTAAVICEICYPFFDRKLFPEDPDEEKLKASLSSPVFVLFRNICSMSTQDNKREXXXXXXSEMQMRQPRVGXXXXXXXKVAYATDPDLSTYRSLCNSLEKPNLKNSLFKDLELLSNDDSKLMVYLLPGLYTAFSTEMVGSPKFAHLIISSLDAAEINELGLQIQKKNLVMFDSNSVVEILKDSLDWGTIEQYFLWELLLAHNISSKHFYGLIPYLDFKKHPEAILRFSNFLRQEKPNYELIKLLLNREVERGDQFTSTLLHFWSSESNSTTSKFVSILHTIISASLGNNMKDKKKNRHSQFAEEGGVDLIKILGHLDFMRLNCKNI--SFLQEESIQSDLQQVLNSKSMLDDIKSRFSELLA 3210
            E M+++V  +L +D FD   ++   A+ + E+    F  ++ PE+  EE L+ S+  P++++FRN+C M   ++   LLL LLSE+  +QP++GY+LLYYL+ + A    ++ Y S   + +  +L   L  D++    DD +L+ +L P +YT F  E + S +  ++I++ +D+A++ EL   +   NLVMF  +SV+ IL  SLDW T EQY  W+L LAHNI  +    ++ +L +K+HPEA+      LR+EKP+ E++K++L+R     DQFT+++L  W  + +   ++ +  L  +I     N++  K+++  S  ++   + L +IL HLD +RLN  N   +F  +  I   LQ V    S  +  K +FS+L +
Sbjct:  596 EVMQEIVDQVLEED-FDSEQLS-VLASCLQELFKAHFRGEVLPEEITEESLEESVGKPLYLIFRNLCQMQEDNSSFSLLLDLLSELYQKQPKIGYHLLYYLRASKAAAGKMNLYESFAQATQLGDLHTCLMMDMKACQEDDVRLLCHLTPSIYTEFPDETLRSGELLNMIVAVIDSAQLQELVCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYCAWQLFLAHNIPLETIIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPCHPDDQFTTSILRHWCMKHDELLAEHIKSL--LIK---NNSLPRKRQSLRSSSSKLAQLTLEQILEHLDNLRLNLTNTKQNFFSQTPILQALQHV--QASCDEAHKMKFSDLFS 971

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Query:  223 IQLGILYFLLTERSQTQFDFKDLILISRDGVKACSGHLITLISENWNRLNTDVRTNVLSILIDFISFPM--ADSLFMAIFKRMITGDLSQSNLWLIENMLNLIEEHKELLVKDKKLLPMIVYTYLRLIPTHYQFSIAMNTPNNNLARLCRKEIALVMDVIRNNFDECCKQVGRDLLFTLTQVSNIPEFNKLWSEMNSSLEKLSNQYTNIGEVFSMGTNKIVIATAIPFDMENWILWTMRNVHHCSTNPYKRYQDLFNKRFFSTVESQNLRPFLIRYIIRAFYPDNEMIGSTLISRWATISWLIVQASSPTVVANCKLALIYDWLFYDKQYDCIMDIEPAILAIMHNLTKYSHVSITLVDFLVKTANLYFPLVKDQIISCCRFGLNDAFRVSVFRSLAPL 1413
            I LG+   +LTE +Q Q  ++DL L+SRDG+      +  ++ E + +L    RT ++ ++ + +   +  AD + M   K++  GD++  N+WL E++L+++ E +E ++K   L+ M VYTYLRLI  H+  +         L  L +KE+   + ++R  F EC   +GRDL+  L  V+ IPEF  LW ++  + + LS Q+T I ++    T++  +A  +  DME  +L+    V        KRYQD F +++ ST +SQ+LR  LIRYI    +P NE++ S ++ RWA I WL+   +S    +N KLAL YDWLF+    D IM+IEPAIL + H++  +  ++ TL+DF+ +    ++P ++  +       LN      V   LAPL
Sbjct:   89 ICLGLFTLILTEPAQAQKCYRDLALVSRDGMNIVLNKINQILMEKYLKLQDTCRTQLVWLVRELVKSGVLGADGVCMTFMKQIAGGDVTAKNIWLAESVLDILTEQREWVLKSSILIAMAVYTYLRLIVDHHGTA--------QLQALRQKEVDFCISLLRERFMECL-MIGRDLVRLLQNVARIPEFELLWKDIIHNPQALSPQFTGILQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRF---GQQKRYQDWFQRQYLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFSPDKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPNFYPPLEGHVRQGVFSSLNHIVEKRVLAHLAPL 475

HSP 2 Score: 179.874 bits (455), Expect = 2.923e-45
Identity = 129/385 (33.51%), Postives = 222/385 (57.66%), Query Frame = 1

Query: 2062 EKMEKVVIAILNDDNFDDLGIAGKTAAVICEICYPFFDRKLFPEDPDEEKLKASLSSPVFVLFRNICSMSTQDNKREXXXXXXSEMQMRQPRVGXXXXXXXKVAYATDPDLSTYRSLCNSLEKPNLKNSLFKDLELLSNDDSKLMVYLLPGLYTAFSTEMVGSPKFAHLIISSLDAAEINELGLQIQKKNLVMFDSNSVVEILKDSLDWGTIEQYFLWELLLAHNISSKHFYGLIPYLDFKKHPEAILRFSNFLRQEKPNYELIKLLLNREVERGDQFTSTLLHFWSSESNSTTSKFVSILHTIISASLGNNMKDKKKNRHSQFAEEGGVDLIKILGHLDFMRLNCKNI--SFLQEESIQSDLQQVLNSKSMLDDIKSRFSELLA 3210
            E M+++V  +L +D FD   ++   A+ + E+    F  ++ PE+  EE L+ S+  P++++FRN+C M   ++   LLL LLSE+  +QP++GY+LLYYL+ + A    ++ Y S   + +  +L   L  D++    DD +L+ +L P +YT F  E + S +  ++I++ +D+A++ EL   +   NLVMF  +SV+ IL  SLDW T EQY  W+L LAHNI  +    ++ +L +K+HPEA+      LR+EKP+ E++K++L+R     DQFT+++L  W  + +   ++ +  L  +I     N++  K+++  S  ++   + L +IL HLD +RLN  N   +F  +  I   LQ V    S  +  K +FS+L +
Sbjct:  596 EVMQEIVDQVLEED-FDSEQLS-VLASCLQELFKAHFRGEVLPEEITEESLEESVGKPLYLIFRNLCQMQEDNSSFSLLLDLLSELYQKQPKIGYHLLYYLRASKAAAGKMNLYESFAQATQLGDLHTCLMMDMKACQEDDVRLLCHLTPSIYTEFPDETLRSGELLNMIVAVIDSAQLQELVCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYCAWQLFLAHNIPLETIIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPCHPDDQFTTSILRHWCMKHDELLAEHIKSL--LIK---NNSLPRKRQSLRSSSSKLAQLTLEQILEHLDNLRLNLTNTKQNFFSQTPILQALQHV--QASCDEAHKMKFSDLFS 971

[Close]

Query:  223 IQLGILYFLLTERSQTQFDFKDLILISRDGVKACSGHLITLISENWNRLNTDVRTNVLSILIDFISFPM--ADSLFMAIFKRMITGDLSQSNLWLIENMLNLIEEHKELLVKDKKLLPMIVYTYLRLIPTHYQFSIAMNTPNNNLARLCRKEIALVMDVIRNNFDECCKQVGRDLLFTLTQVSNIPEFNKLWSEMNSSLEKLSNQYTNIGEVFSMGTNKIVIATAIPFDMENWILWTMRNVHHCSTNPYKRYQDLFNKRFFSTVESQNLRPFLIRYIIRAFYPDNEMIGSTLISRWATISWLIVQASSPTVVANCKLALIYDWLFYDKQYDCIMDIEPAILAIMHNLTKYSHVSITLVDFLVKTANLYFPLVKDQIISCCRFGLNDAFRVSVFRSLAPL 1413
            I LG+   +LTE +Q Q  ++DL L+SRDG+      +  ++ E + +L    RT ++ ++ + +   +  AD + M   K++  GD++  N+WL E++L+++ E +E ++K   L+ M VYTYLRLI  H+  +         L  L +KE+   + ++R  F EC   +GRDL+  L  V+ IPEF  LW ++  + + LS Q+T I ++    T++  +A  +  DME  +L+    V        KRYQD F +++ ST +SQ+LR  LIRYI    +P NE++ S ++ RWA I WL+   +S    +N KLAL YDWLF+    D IM+IEPAIL + H++  +  ++ TL+DF+ +    ++P ++  +       LN      V   LAPL
Sbjct:   89 ICLGLFTLILTEPAQAQKCYRDLALVSRDGMNIVLNKINQILMEKYLKLQDTCRTQLVWLVRELVKSGVLGADGVCMTFMKQIAGGDVTAKNIWLAESVLDILTEQREWVLKSSILIAMAVYTYLRLIVDHHGTA--------QLQALRQKEVDFCISLLRERFMECL-MIGRDLVRLLQNVARIPEFELLWKDIIHNPQALSPQFTGILQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRF---GQQKRYQDWFQRQYLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFSPDKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPNFYPPLEGHVRQGVFSSLNHIVEKRVLAHLAPL 475

HSP 2 Score: 179.874 bits (455), Expect = 2.923e-45
Identity = 129/385 (33.51%), Postives = 222/385 (57.66%), Query Frame = 1

Query: 2062 EKMEKVVIAILNDDNFDDLGIAGKTAAVICEICYPFFDRKLFPEDPDEEKLKASLSSPVFVLFRNICSMSTQDNKREXXXXXXSEMQMRQPRVGXXXXXXXKVAYATDPDLSTYRSLCNSLEKPNLKNSLFKDLELLSNDDSKLMVYLLPGLYTAFSTEMVGSPKFAHLIISSLDAAEINELGLQIQKKNLVMFDSNSVVEILKDSLDWGTIEQYFLWELLLAHNISSKHFYGLIPYLDFKKHPEAILRFSNFLRQEKPNYELIKLLLNREVERGDQFTSTLLHFWSSESNSTTSKFVSILHTIISASLGNNMKDKKKNRHSQFAEEGGVDLIKILGHLDFMRLNCKNI--SFLQEESIQSDLQQVLNSKSMLDDIKSRFSELLA 3210
            E M+++V  +L +D FD   ++   A+ + E+    F  ++ PE+  EE L+ S+  P++++FRN+C M   ++   LLL LLSE+  +QP++GY+LLYYL+ + A    ++ Y S   + +  +L   L  D++    DD +L+ +L P +YT F  E + S +  ++I++ +D+A++ EL   +   NLVMF  +SV+ IL  SLDW T EQY  W+L LAHNI  +    ++ +L +K+HPEA+      LR+EKP+ E++K++L+R     DQFT+++L  W  + +   ++ +  L  +I     N++  K+++  S  ++   + L +IL HLD +RLN  N   +F  +  I   LQ V    S  +  K +FS+L +
Sbjct:  596 EVMQEIVDQVLEED-FDSEQLS-VLASCLQELFKAHFRGEVLPEEITEESLEESVGKPLYLIFRNLCQMQEDNSSFSLLLDLLSELYQKQPKIGYHLLYYLRASKAAAGKMNLYESFAQATQLGDLHTCLMMDMKACQEDDVRLLCHLTPSIYTEFPDETLRSGELLNMIVAVIDSAQLQELVCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYCAWQLFLAHNIPLETIIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPCHPDDQFTTSILRHWCMKHDELLAEHIKSL--LIK---NNSLPRKRQSLRSSSSKLAQLTLEQILEHLDNLRLNLTNTKQNFFSQTPILQALQHV--QASCDEAHKMKFSDLFS 971

[Close]

Query:  223 IQLGILYFLLTERSQTQFDFKDLILISRDGVKACSGHLITLISENWNRLNTDVRTNVLSILIDFISFPM--ADSLFMAIFKRMITGDLSQSNLWLIENMLNLIEEHKELLVKDKKLLPMIVYTYLRLIPTHYQFSIAMNTPNNNLARLCRKEIALVMDVIRNNFDECCKQVGRDLLFTLTQVSNIPEFNKLWSEMNSSLEKLSNQYTNIGEVFSMGTNKIVIATAIPFDMENWILWTMRNVHHCSTNPYKRYQDLFNKRFFSTVESQNLRPFLIRYIIRAFYPDNEMIGSTLISRWATISWLIVQASSPTVVANCKLALIYDWLFYDKQYDCIMDIEPAILAIMHNLTKYSHVSITLVDFLVKTANLYFPLVKDQIISCCRFGLNDAFRVSVFRSLAPL 1413
            I LG+   +LTE +Q Q  ++DL L+SRDG+      +  ++ E + +L    RT ++ ++ + +   +  AD + M   K++  GD++  N+WL E++L+++ E +E ++K   L+ M VYTYLRLI  H+  +         L  L +KE+   + ++R  F EC   +GRDL+  L  V+ IPEF  LW ++  + + LS Q+T I ++    T++  +A  +  DME  +L+    V        KRYQD F +++ ST +SQ+LR  LIRYI    +P NE++ S ++ RWA I WL+   +S    +N KLAL YDWLF+    D IM+IEPAIL + H++  +  ++ TL+DF+ +    ++P ++  +       LN      V   LAPL
Sbjct:   89 ICLGLFTLILTEPAQAQKCYRDLALVSRDGMNIVLNKINQILMEKYLKLQDTCRTQLVWLVRELVKSGVLGADGVCMTFMKQIAGGDVTAKNIWLAESVLDILTEQREWVLKSSILIAMAVYTYLRLIVDHHGTA--------QLQALRQKEVDFCISLLRERFMECL-MIGRDLVRLLQNVARIPEFELLWKDIIHNPQALSPQFTGILQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRF---GQQKRYQDWFQRQYLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFSPDKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPNFYPPLEGHVRQGVFSSLNHIVEKRVLAHLAPL 475

HSP 2 Score: 179.874 bits (455), Expect = 2.923e-45
Identity = 129/385 (33.51%), Postives = 222/385 (57.66%), Query Frame = 1

Query: 2062 EKMEKVVIAILNDDNFDDLGIAGKTAAVICEICYPFFDRKLFPEDPDEEKLKASLSSPVFVLFRNICSMSTQDNKREXXXXXXSEMQMRQPRVGXXXXXXXKVAYATDPDLSTYRSLCNSLEKPNLKNSLFKDLELLSNDDSKLMVYLLPGLYTAFSTEMVGSPKFAHLIISSLDAAEINELGLQIQKKNLVMFDSNSVVEILKDSLDWGTIEQYFLWELLLAHNISSKHFYGLIPYLDFKKHPEAILRFSNFLRQEKPNYELIKLLLNREVERGDQFTSTLLHFWSSESNSTTSKFVSILHTIISASLGNNMKDKKKNRHSQFAEEGGVDLIKILGHLDFMRLNCKNI--SFLQEESIQSDLQQVLNSKSMLDDIKSRFSELLA 3210
            E M+++V  +L +D FD   ++   A+ + E+    F  ++ PE+  EE L+ S+  P++++FRN+C M   ++   LLL LLSE+  +QP++GY+LLYYL+ + A    ++ Y S   + +  +L   L  D++    DD +L+ +L P +YT F  E + S +  ++I++ +D+A++ EL   +   NLVMF  +SV+ IL  SLDW T EQY  W+L LAHNI  +    ++ +L +K+HPEA+      LR+EKP+ E++K++L+R     DQFT+++L  W  + +   ++ +  L  +I     N++  K+++  S  ++   + L +IL HLD +RLN  N   +F  +  I   LQ V    S  +  K +FS+L +
Sbjct:  596 EVMQEIVDQVLEED-FDSEQLS-VLASCLQELFKAHFRGEVLPEEITEESLEESVGKPLYLIFRNLCQMQEDNSSFSLLLDLLSELYQKQPKIGYHLLYYLRASKAAAGKMNLYESFAQATQLGDLHTCLMMDMKACQEDDVRLLCHLTPSIYTEFPDETLRSGELLNMIVAVIDSAQLQELVCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYCAWQLFLAHNIPLETIIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPCHPDDQFTTSILRHWCMKHDELLAEHIKSL--LIK---NNSLPRKRQSLRSSSSKLAQLTLEQILEHLDNLRLNLTNTKQNFFSQTPILQALQHV--QASCDEAHKMKFSDLFS 971

[Close]

BLAST of Integrator complex subunit 3 vs. Ensembl Human
Match: INTS3 (integrator complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:26153])

HSP 1 Score: 173.326 bits (438), Expect = 1.256e-47
Identity = 104/298 (34.90%), Postives = 159/298 (53.36%), Query Frame = 1

Query:  577 VYTYLRLIPTHYQFSIAMNTPNNNLARLCRKEIALVMDVIRNNFDECCKQVGRDLLFTLTQVSNIPEFNKLWSEMNSSLEKLSNQYTNIGEVFSMGTNKIVIATAIPFDMENWILWTMRNVHHCSTNPYKRYQDLFNKRFFSTVESQNLRPFLIRYIIRAFYPDNEMIGSTLISRWATISWLIVQASSPTVVANCKLALIYDWLFYDKQYDCIMDIEPAILAIMHNLTKYSHVSITLVDFLVKTANLYFPLVKDQIISCCRFGLNDAFRVSVFRSLAPLHEVLRHHIELYKQFLELIG 1470
            VYTYLRLI  H+            L  L +KE+   + ++R  F EC   +GRDL+  L  V+ IPEF  LW ++  + + LS Q+T I ++    T++  +A  +  DME  +L+    V        KRYQD F +++ ST +SQ+LR  LIRYI    +P NE++ S ++ RWA I WL+   +S    +N KLAL YDWLF+    D IM+IEPAIL + H++  +  ++ TL+DF+ +    ++P ++  +            R  VF SL  + E      + Y  +L L+G
Sbjct:    1 VYTYLRLIVDHHG--------TAQLQALRQKEVDFCISLLRERFMECL-MIGRDLVRLLQNVARIPEFELLWKDIIHNPQALSPQFTGILQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRF---GQQKRYQDWFQRQYLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFSPDKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPNFYPPLEGHV------------RQGVFSSLNHIVEKRVLACKKYWLYLRLLG 274

[Close]

BLAST of Integrator complex subunit 3 vs. Ensembl Celegans
Match: Y92H12A.4 (pep chromosome:WBcel235:I:1520239:1539206:1 gene:WBGene00022360.1 transcript:Y92H12A.4d.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y92H12A.4)

HSP 1 Score: 91.2781 bits (225), Expect = 1.866e-18
Identity = 79/328 (24.09%), Postives = 154/328 (46.95%), Query Frame = 1

Query: 2062 EKMEKVVIAILN-DDNFDD----------LGIAGKTAAVICEICYPFFDRKLFPEDPDEEKLKASLSSPVFVLFRNICSMSTQDNKR-EXXXXXXSEMQMRQPRVGXXXXXXXKVAYATDPD--LSTYRSLCNSLEKPNLKNSLFKDLELLSNDDSKLMVYLLPGLYTAFSTEMVGSPKFAHLIISSLDAAEINELGLQIQKKNLVMFDSNSVVEILKDSLDWGTIEQYFLWELLLAHNISSKHFYGLIPYLDFKKHPEAILRFSNFLRQ--EKPNYELIKLLLNREVERGDQFTSTLLHFWSSESNSTTSKFVSILHTIISASLGNN 2997
            E +E +++++L   D FD+          LGI G   A          ++ L P  P+E+ L  + + P++   + +CS    D    +++  +++ M+ +   + Y  LY++K      P   +  Y+++   +   ++   L  DL+L + +D++L  YL+P +++ F  E++ +P     + ++LDA ++     +I ++ + +F   S  +++ DS+DW T  Q+  W L+ A  +  + F   IP  D   H EAI      +++   +P   LI+ L NR   + D FT   +     +S     K   I+  +I   LGNN
Sbjct:  209 EAVEGLLVSLLTTGDVFDESQQELAAQCLLGIMGSVVAD---------EQSLLP--PNEKDLSEAFTHPIYSFLKVLCSPPDNDEASSDVMAAMMAAMREKDSSLTYVFLYFIKGTAGGRPTECIECYKNIAK-MSGRSVDEMLASDLQLCAVNDNRLFAYLVPFVFSQFEEEVMSTPALLATLCANLDAIQLRSFVSEIIREEIKIFRKESFPKMVMDSVDWATTPQWVFWHLVHADGVPIEWFLSTIPKFDAVGHDEAIANILLMMKRMDREPWAGLIRALFNRVPNKDDTFTIDAMKVLIEDSEQ-CQKVAEIVAQLIKKLLGNN 523

[Close]

BLAST of Integrator complex subunit 3 vs. Ensembl Celegans
Match: Y92H12A.4 (pep chromosome:WBcel235:I:1517542:1539206:1 gene:WBGene00022360.1 transcript:Y92H12A.4c.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y92H12A.4)

HSP 1 Score: 90.5077 bits (223), Expect = 3.984e-18
Identity = 79/328 (24.09%), Postives = 154/328 (46.95%), Query Frame = 1

Query: 2062 EKMEKVVIAILN-DDNFDD----------LGIAGKTAAVICEICYPFFDRKLFPEDPDEEKLKASLSSPVFVLFRNICSMSTQDNKR-EXXXXXXSEMQMRQPRVGXXXXXXXKVAYATDPD--LSTYRSLCNSLEKPNLKNSLFKDLELLSNDDSKLMVYLLPGLYTAFSTEMVGSPKFAHLIISSLDAAEINELGLQIQKKNLVMFDSNSVVEILKDSLDWGTIEQYFLWELLLAHNISSKHFYGLIPYLDFKKHPEAILRFSNFLRQ--EKPNYELIKLLLNREVERGDQFTSTLLHFWSSESNSTTSKFVSILHTIISASLGNN 2997
            E +E +++++L   D FD+          LGI G   A          ++ L P  P+E+ L  + + P++   + +CS    D    +++  +++ M+ +   + Y  LY++K      P   +  Y+++   +   ++   L  DL+L + +D++L  YL+P +++ F  E++ +P     + ++LDA ++     +I ++ + +F   S  +++ DS+DW T  Q+  W L+ A  +  + F   IP  D   H EAI      +++   +P   LI+ L NR   + D FT   +     +S     K   I+  +I   LGNN
Sbjct:  429 EAVEGLLVSLLTTGDVFDESQQELAAQCLLGIMGSVVAD---------EQSLLP--PNEKDLSEAFTHPIYSFLKVLCSPPDNDEASSDVMAAMMAAMREKDSSLTYVFLYFIKGTAGGRPTECIECYKNIAK-MSGRSVDEMLASDLQLCAVNDNRLFAYLVPFVFSQFEEEVMSTPALLATLCANLDAIQLRSFVSEIIREEIKIFRKESFPKMVMDSVDWATTPQWVFWHLVHADGVPIEWFLSTIPKFDAVGHDEAIANILLMMKRMDREPWAGLIRALFNRVPNKDDTFTIDAMKVLIEDSEQ-CQKVAEIVAQLIKKLLGNN 743

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BLAST of Integrator complex subunit 3 vs. Ensembl Celegans
Match: Y92H12A.4 (pep chromosome:WBcel235:I:1514755:1539496:1 gene:WBGene00022360.1 transcript:Y92H12A.4a.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y92H12A.4)

HSP 1 Score: 90.1225 bits (222), Expect = 6.271e-18
Identity = 79/328 (24.09%), Postives = 154/328 (46.95%), Query Frame = 1

Query: 2062 EKMEKVVIAILN-DDNFDD----------LGIAGKTAAVICEICYPFFDRKLFPEDPDEEKLKASLSSPVFVLFRNICSMSTQDN-KREXXXXXXSEMQMRQPRVGXXXXXXXKVAYATDPD--LSTYRSLCNSLEKPNLKNSLFKDLELLSNDDSKLMVYLLPGLYTAFSTEMVGSPKFAHLIISSLDAAEINELGLQIQKKNLVMFDSNSVVEILKDSLDWGTIEQYFLWELLLAHNISSKHFYGLIPYLDFKKHPEAILRFSNFLRQ--EKPNYELIKLLLNREVERGDQFTSTLLHFWSSESNSTTSKFVSILHTIISASLGNN 2997
            E +E +++++L   D FD+          LGI G   A          ++ L P  P+E+ L  + + P++   + +CS    D    +++  +++ M+ +   + Y  LY++K      P   +  Y+++   +   ++   L  DL+L + +D++L  YL+P +++ F  E++ +P     + ++LDA ++     +I ++ + +F   S  +++ DS+DW T  Q+  W L+ A  +  + F   IP  D   H EAI      +++   +P   LI+ L NR   + D FT   +     +S     K   I+  +I   LGNN
Sbjct:  593 EAVEGLLVSLLTTGDVFDESQQELAAQCLLGIMGSVVAD---------EQSLLP--PNEKDLSEAFTHPIYSFLKVLCSPPDNDEASSDVMAAMMAAMREKDSSLTYVFLYFIKGTAGGRPTECIECYKNIAK-MSGRSVDEMLASDLQLCAVNDNRLFAYLVPFVFSQFEEEVMSTPALLATLCANLDAIQLRSFVSEIIREEIKIFRKESFPKMVMDSVDWATTPQWVFWHLVHADGVPIEWFLSTIPKFDAVGHDEAIANILLMMKRMDREPWAGLIRALFNRVPNKDDTFTIDAMKVLIEDSEQ-CQKVAEIVAQLIKKLLGNN 907

[Close]

BLAST of Integrator complex subunit 3 vs. Ensembl Celegans
Match: Y92H12A.4 (pep chromosome:WBcel235:I:1514755:1540847:1 gene:WBGene00022360.1 transcript:Y92H12A.4a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y92H12A.4)

HSP 1 Score: 90.1225 bits (222), Expect = 6.271e-18
Identity = 79/328 (24.09%), Postives = 154/328 (46.95%), Query Frame = 1

Query: 2062 EKMEKVVIAILN-DDNFDD----------LGIAGKTAAVICEICYPFFDRKLFPEDPDEEKLKASLSSPVFVLFRNICSMSTQDN-KREXXXXXXSEMQMRQPRVGXXXXXXXKVAYATDPD--LSTYRSLCNSLEKPNLKNSLFKDLELLSNDDSKLMVYLLPGLYTAFSTEMVGSPKFAHLIISSLDAAEINELGLQIQKKNLVMFDSNSVVEILKDSLDWGTIEQYFLWELLLAHNISSKHFYGLIPYLDFKKHPEAILRFSNFLRQ--EKPNYELIKLLLNREVERGDQFTSTLLHFWSSESNSTTSKFVSILHTIISASLGNN 2997
            E +E +++++L   D FD+          LGI G   A          ++ L P  P+E+ L  + + P++   + +CS    D    +++  +++ M+ +   + Y  LY++K      P   +  Y+++   +   ++   L  DL+L + +D++L  YL+P +++ F  E++ +P     + ++LDA ++     +I ++ + +F   S  +++ DS+DW T  Q+  W L+ A  +  + F   IP  D   H EAI      +++   +P   LI+ L NR   + D FT   +     +S     K   I+  +I   LGNN
Sbjct:  593 EAVEGLLVSLLTTGDVFDESQQELAAQCLLGIMGSVVAD---------EQSLLP--PNEKDLSEAFTHPIYSFLKVLCSPPDNDEASSDVMAAMMAAMREKDSSLTYVFLYFIKGTAGGRPTECIECYKNIAK-MSGRSVDEMLASDLQLCAVNDNRLFAYLVPFVFSQFEEEVMSTPALLATLCANLDAIQLRSFVSEIIREEIKIFRKESFPKMVMDSVDWATTPQWVFWHLVHADGVPIEWFLSTIPKFDAVGHDEAIANILLMMKRMDREPWAGLIRALFNRVPNKDDTFTIDAMKVLIEDSEQ-CQKVAEIVAQLIKKLLGNN 907

[Close]

BLAST of Integrator complex subunit 3 vs. Ensembl Fly
Match: IntS3 (gene:FBgn0262117 transcript:FBtr0111268)

HSP 1 Score: 220.705 bits (561), Expect = 1.713e-58
Identity = 135/437 (30.89%), Postives = 235/437 (53.78%), Query Frame = 1

Query:  205 EEDNMRIQLGILYFLLTERSQTQFDFKDLILISRDGVKACSGHLITLISENWNRLNTDVRTNVLSILIDFISFPM--ADSLFMAIFKRMITGDLSQSNLWLIENMLNLIEEHKELLVKDKKLLPMIVYTYLRLIPTHYQFSIAMNTPNNNLARLCRKEIALVMDVIRNNFDECCKQVGRDLLFTLTQVSNIPEFNKLWSEMNSSLEKLSNQYTNIGEVFSMGTNKIVIATAIPFDMENWILWTMRNVHHCSTNPYKRYQDLFNKRFFSTVESQNLRPFLIRYIIRAFYPDNEMIGSTLISRWATISWLIVQASSPTVVANCKLALIYDWLFYDKQYDCIMDIEPAILAIMHNLTKYSHVSITLVDFLVKTANLYFPLVKDQIISCCRFGLNDAFRVSVFRSLAPLHEVLRHHIELYKQFLELIGDTSNVYPQIPLNN 1509
            E+ +  I +G LY +LT+ S     ++D+ L+SRDG+     +L  L++E + +L    R  ++ +L +F+   +   +++     ++   GD+S  NL+LIE++L++  E +  L  +  L+   VY+++RLI  H          N  L  L +KE+   + +IR  F +    +GRD +  L  V+ IPEF +LW ++  + + L   +  I ++  + T++  +   +  +ME  I +   +V   +    KRYQD F  ++F+T ES +LR  LIR+II   +P N+M+ S +I RWA I WLI   ++P   AN KL+L YDWLF+D   D IM+IEP IL + H++  +  VS TL+DFL +    +F   +D+I    R G+ ++ ++ + + + P  + L    +L ++   LI D    +   P N+
Sbjct:   61 EKQHEEISIGFLYIMLTDPSMASKTYRDVTLVSRDGMNGIVTNLTFLVAEKYTKLTEVARRQLIWLLREFVKHQVLSVENVIWNCLRQAGGGDVSSRNLFLIESLLDIFIEFRTWLETNPFLVQSTVYSFVRLIEDH---------ANPALLSLRQKEVKFTISLIRERFHDIIP-LGRDFVRLLQNVARIPEFEQLWRDILFNPKMLHQTFNGIWQLLHIRTSRRFLQCRLLPEMERKISFLASSVKFGNQ---KRYQDWFQDKYFATPESHSLRSDLIRFIINVIHPTNDMLCSDIIPRWAIIGWLISSCTNPIASANAKLSLFYDWLFFDPAKDNIMNIEPGILVMYHSIRNHPFVSSTLLDFLCRITKNFFVKHEDKI----RIGVYNSLKLILEKQVIPNLQPLFESPKLDRELRNLIRDNFREFLSPPANH 480

HSP 2 Score: 125.561 bits (314), Expect = 1.186e-28
Identity = 93/360 (25.83%), Postives = 180/360 (50.00%), Query Frame = 1

Query: 2176 RKLFPEDPDEEK-LKASLSSPVFVLFRNICSMSTQDNKREXXXXXXSEMQMRQPRVGXXXXXXXKV----------AYATDPDLSTYRSLCNSLEKPNLKNSLFKDLELLSNDDSKLMVYLLPGLYTAFSTEMVGSPKFAHLIISSLDAAEINELGLQIQKKNLVMFDSNSVVEILKDSLDWGTIEQYFLWELLLAHNISSKHFYGLIPYLDFKKHPEAILRFSNFLRQEKPNYELIKLLLNREVE-RGDQFTSTLLHFWSSESNSTTSKFVSILHTIISASLGNNMKDKKKNRHSQFAEEGGVDLIKILGHLDFMRLNCKN---ISFLQEESIQSDLQQVLNSKSMLDDIKSRFSELLA 3210
            + +F E   EEK L  S+S P++ LFR +      +  ++    LLSE+    P +GY LLY++K+            +     + YR +C++ ++  + N L +DL+LL  +++ + ++LLP +Y  F +    +     + +  +DA  + ++   I +  L +F  + +++ ++ SL++ T EQ+ LW+++ AH++  +    ++P L+   HPEA+  F   L+ E+P  E+I+L+L+RE + +GD F ++ L FW        S+ ++ L T    S   N + +     S        D  ++L HL+  R +C++         + +Q  LQ   +  +  D  K +F +L A
Sbjct:  640 QNIFSESKTEEKHLAKSISYPLYGLFRFL--YENDEKSKKPFQTLLSEICEGIPEIGYLLLYFMKIYCKLQTRKNSQQSYQFKTTIYRQICDAADE-KIGNCLLRDLDLLEKENTNIFLWLLPDIYREFKSIATNNTDLLRITLRCIDAKNVRDILYSIAQGKLTIFKQDGLIDCIRQSLEFETYEQFCLWQIVQAHDVPLRCIQDILPELEAGSHPEALSHFLLLLKNEEPTNEIIRLMLSRESKSKGDPFVTSALRFWCQRYEEKLSEIIASLLTSKYPSSSPNKRKRPPKGISVSTSTPSAD--QVLNHLEHYRRSCRHGTGTGLYVHDMMQRALQSAYSHSN--DSTKKQFCDLFA 992

[Close]

BLAST of Integrator complex subunit 3 vs. Ensembl Zebrafish
Match: ints3 (integrator complex subunit 3 [Source:NCBI gene;Acc:560575])

HSP 1 Score: 248.44 bits (633), Expect = 1.356e-67
Identity = 139/414 (33.57%), Postives = 230/414 (55.56%), Query Frame = 1

Query:  178 ALIINRGQSEEDNMRIQLGILYFLLTERSQTQFDFKDLILISRDGVKACSGHLITLISENWNRLNTDVRTNVLSILIDFISFPM--ADSLFMAIFKRMITGDLSQSNLWLIENMLNLIEEHKELLVKDKKLLPMIVYTYLRLIPTHYQFSIAMNTPNNNLARLCRKEIALVMDVIRNNFDECCKQVGRDLLFTLTQVSNIPEFNKLWSEMNSSLEKLSNQYTNIGEVFSMGTNKIVIATAIPFDMENWILWTMRNVHHCSTNPYKRYQDLFNKRFFSTVESQNLRPFLIRYIIRAFYPDNEMIGSTLISRWATISWLIVQASSPTVVANCKLALIYDWLFYDKQYDCIMDIEPAILAIMHNLTKYSHVSITLVDFLVKTANLYFPLVKDQIISCCRFGLNDAFRVSVFRSLAPL 1413
            AL  +  +  + +  + LG+   LLTE  Q Q  ++DL L++RDG+      +  ++ E + +L    RT ++ ++ + +   +  AD + M + K++  GD+S  NLWL EN+L+++ + +E ++K   L+ M +YTYLRLI  H            +L  L ++E+   + ++R  F EC   +GRDL+  L  V+ IPE   +W ++  S + LS Q+T I ++ +  T++  +A  +  DME  +L+    V        KRYQD F +++ ST ESQ+LR  LIRYI    +P NE++ S ++ RWA I WL+   +S    +N KLAL YDWLF++ + D IM+IEPAIL + H++  +  ++ TL+DF+ +    +FP ++ Q+       LN      V   LAPL
Sbjct:   52 ALTAHVCKGPQQHEEVCLGLFTLLLTEPPQAQRCYRDLTLVNRDGMNVVLMKINQILMEKFLKLQDVCRTQLVWLVRELVKSGVIGADGVLMTLMKQIAGGDISSKNLWLAENVLDILVDQREWVLKSGMLVAMSLYTYLRLIVDH---------GTTSLLPLRQREVDFCIGLLRERFMECFI-IGRDLVRLLQNVARIPEMELVWRDLLHSPQTLSPQFTGILQLLTSRTSRKFLACRLTPDMETKLLFMTSRVRF---GQQKRYQDWFQRQYLSTAESQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFNPEKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPHFFPPLEGQVRQGVFNSLNFIMEKRVLAHLAPL 452

HSP 2 Score: 187.963 bits (476), Expect = 4.257e-48
Identity = 135/387 (34.88%), Postives = 220/387 (56.85%), Query Frame = 1

Query: 2062 EKMEKVVIAILNDDNFDDLGIAGKTAAVICEICYPFFDRKLFPEDPDEEKLKASLSSPVFVLFRNICSMSTQDNKREXXXXXXSEMQMRQPRVGXXXXXXXKVAYATDPDLSTYRSLCNSLEKPNLKNSLFKDLELLSNDDSKLMVYLLPGLYTAFSTEMVGSPKFAHLIISSLDAAEINELGLQIQKKNLVMFDSNSVVEILKDSLDWGTIEQYFLWELLLAHNISSKHFYGLIPYLDFKKHPEAILRFSNFLRQEKPNYELIKLLLNREVERGDQFTSTLLHFWSSESNSTTSKFVSILHTIISASL--GNNMKDKKKNRHSQFAEEGGVDLIKILGHLDFMRLNCKNI--SFLQEESIQSDLQQVLNSKSMLDDIKSRFSELLA 3210
            E M+++V  IL +D FD   ++   A+ + E+    F   + PE+  EE L+ S+  PV ++FRN+C M   ++   +LL LL+E+  +QP++GY+LLYYLK + A    +S Y S   +    +L   L  D++    DD +L+ YL P +Y+ F  E + S +  ++I++ +D+A++ EL   +   NLVMF  +SV+ IL  SLDW T EQY  W+L LAH+I  +    ++ +L +K+HPEA+      LR+EKP+ E++K++L+R   + DQFT+++L  W       T+K   +L   I A L   NNM  K+++  S  ++   + L ++L HLD +RL+  N   +F  +  I   LQ V    S  +  K RFS+L +
Sbjct:  573 EVMQEIVDLILEED-FDSEQMS-TLASCLAELFKSHFRGDVLPEEITEESLEESVCKPVCLIFRNLCQMQEDNSGFSVLLDLLAELYQKQPKIGYHLLYYLKASKAASGKMSLYESFAQATALGDLHTCLMMDMKACQEDDVRLLCYLTPSIYSEFPDETLRSGELLNMIVAVIDSAQLQELMCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYSTWQLFLAHSIPLETIIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPYHQEDQFTTSILRHW-------TAKHDDLLGEHIKALLIKNNNMPRKRQSLRSSSSKLAQLTLEQMLEHLDSLRLSLSNTKNNFFSQTPILQALQHV--QASCDEAHKMRFSDLFS 948

[Close]

BLAST of Integrator complex subunit 3 vs. Ensembl Mouse
Match: Ints3 (integrator complex subunit 3 [Source:MGI Symbol;Acc:MGI:2140050])

HSP 1 Score: 249.21 bits (635), Expect = 1.142e-67
Identity = 142/434 (32.72%), Postives = 235/434 (54.15%), Query Frame = 1

Query:  118 KNLSIIDESGEYVRSLKEDKALIINRGQSEEDNMRIQLGILYFLLTERSQTQFDFKDLILISRDGVKACSGHLITLISENWNRLNTDVRTNVLSILIDFISFPM--ADSLFMAIFKRMITGDLSQSNLWLIENMLNLIEEHKELLVKDKKLLPMIVYTYLRLIPTHYQFSIAMNTPNNNLARLCRKEIALVMDVIRNNFDECCKQVGRDLLFTLTQVSNIPEFNKLWSEMNSSLEKLSNQYTNIGEVFSMGTNKIVIATAIPFDMENWILWTMRNVHHCSTNPYKRYQDLFNKRFFSTVESQNLRPFLIRYIIRAFYPDNEMIGSTLISRWATISWLIVQASSPTVVANCKLALIYDWLFYDKQYDCIMDIEPAILAIMHNLTKYSHVSITLVDFLVKTANLYFPLVKDQIISCCRFGLNDAFRVSVFRSLAPL 1413
            + +SI+      V   + + AL     +    +  I LG+   +LTE +Q Q  ++DL L+SRDG+      +  L+ E + +L    RT ++ ++ + +   +  AD + M   K++  GD++  N+WL E++L+++ E +E ++K   L+ M VYTYLRLI  H+  +         L  L +KE+   + ++R  F EC   +GRDL+  L  V+ IPEF  LW ++  + + LS Q+T I ++    T++  +A  +  DME  +L+    V        KRYQD F +++ ST +SQ+LR  LIRYI    +P NE++ S ++ RWA I WL+   +S    +N KLAL YDWLF+  + D IM+IEPAIL + H++  +  ++ TL+DF+ +    ++P ++  +       LN      V   LAPL
Sbjct:   53 RCMSIVTSMTAGVSEREANDALNAYVCKGPPQHEEICLGLFTLVLTEPAQAQKCYRDLALVSRDGMNIVLNKINQLLMEKYLKLQDTCRTQLVWLVRELVKSGVLGADGVCMTFMKQIAGGDVTAKNIWLAESVLDILTEQREWVLKSSILIAMAVYTYLRLIVDHHGTA--------QLQTLRQKEVDFCISLLRERFMECL-MIGRDLVRLLQNVARIPEFELLWKDIIHNPQALSPQFTGILQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRF---GQQKRYQDWFQRQYLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFSPEKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPNFYPPLEGHVRQGVFSSLNHIVEKRVLAHLAPL 474

HSP 2 Score: 180.644 bits (457), Expect = 1.230e-45
Identity = 129/385 (33.51%), Postives = 222/385 (57.66%), Query Frame = 1

Query: 2062 EKMEKVVIAILNDDNFDDLGIAGKTAAVICEICYPFFDRKLFPEDPDEEKLKASLSSPVFVLFRNICSMSTQDNKREXXXXXXSEMQMRQPRVGXXXXXXXKVAYATDPDLSTYRSLCNSLEKPNLKNSLFKDLELLSNDDSKLMVYLLPGLYTAFSTEMVGSPKFAHLIISSLDAAEINELGLQIQKKNLVMFDSNSVVEILKDSLDWGTIEQYFLWELLLAHNISSKHFYGLIPYLDFKKHPEAILRFSNFLRQEKPNYELIKLLLNREVERGDQFTSTLLHFWSSESNSTTSKFVSILHTIISASLGNNMKDKKKNRHSQFAEEGGVDLIKILGHLDFMRLNCKNI--SFLQEESIQSDLQQVLNSKSMLDDIKSRFSELLA 3210
            E M+++V  +L +D FD   ++   A+ + E+    F  ++ PE+  EE L+ S+  P++++FRN+C M   ++   LLL LLSE+  +QP++GY+LLYYL+ + A    ++ Y S   + +  +L   L  D++    DD +L+ +L P +YT F  E + S +  ++I++ +D+A++ EL   +   NLVMF  +SV+ IL  SLDW T EQY  W+L LAHNI  +    ++ +L +K+HPEA+      LR+EKP+ E++K++L+R     DQFT+++L  W  + +   ++ +  L  +I     N++  K+++  S  ++   + L +IL HLD +RLN  N   +F  +  I   LQ V    S  +  K +FS+L +
Sbjct:  595 EVMQEIVDQVLEED-FDSEQLS-VLASCLQELFKAHFRGEVLPEEVTEESLEESVGKPLYLIFRNLCQMQEDNSSFSLLLDLLSELYQKQPKIGYHLLYYLRASKAAAGKMNLYESFAQATQLGDLHTCLMMDMKACQEDDVRLLCHLTPSIYTEFPDETLRSGELLNMIVAVIDSAQLQELVCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYCAWQLFLAHNIPLETIIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPCHPDDQFTTSILRHWCMKHDELLAEHIKAL--LIK---NNSLPRKRQSLRSSSSKLAQLTLEQILEHLDNLRLNLANTKQNFFSQTPILQALQHV--QASCDEAHKMKFSDLFS 970

[Close]

Query:  118 KNLSIIDESGEYVRSLKEDKALIINRGQSEEDNMRIQLGILYFLLTERSQTQFDFKDLILISRDGVKACSGHLITLISENWNRLNTDVRTNVLSILIDFISFPM--ADSLFMAIFKRMITGDLSQSNLWLIENMLNLIEEHKELLVKDKKLLPMIVYTYLRLIPTHYQFSIAMNTPNNNLARLCRKEIALVMDVIRNNFDECCKQVGRDLLFTLTQVSNIPEFNKLWSEMNSSLEKLSNQYTNIGEVFSMGTNKIVIATAIPFDMENWILWTMRNVHHCSTNPYKRYQDLFNKRFFSTVESQNLRPFLIRYIIRAFYPDNEMIGSTLISRWATISWLIVQASSPTVVANCKLALIYDWLFYDKQYDCIMDIEPAILAIMHNLTKYSHVSITLVDFLVKTANLYFPLVKDQIISCCRFGLNDAFRVSVFRSLAPL 1413
            + +SI+      V   + + AL     +    +  I LG+   +LTE +Q Q  ++DL L+SRDG+      +  L+ E + +L    RT ++ ++ + +   +  AD + M   K++  GD++  N+WL E++L+++ E +E ++K   L+ M VYTYLRLI  H+  +         L  L +KE+   + ++R  F EC   +GRDL+  L  V+ IPEF  LW ++  + + LS Q+T I ++    T++  +A  +  DME  +L+    V        KRYQD F +++ ST +SQ+LR  LIRYI    +P NE++ S ++ RWA I WL+   +S    +N KLAL YDWLF+  + D IM+IEPAIL + H++  +  ++ TL+DF+ +    ++P ++  +       LN      V   LAPL
Sbjct:   53 RCMSIVTSMTAGVSEREANDALNAYVCKGPPQHEEICLGLFTLVLTEPAQAQKCYRDLALVSRDGMNIVLNKINQLLMEKYLKLQDTCRTQLVWLVRELVKSGVLGADGVCMTFMKQIAGGDVTAKNIWLAESVLDILTEQREWVLKSSILIAMAVYTYLRLIVDHHGTA--------QLQTLRQKEVDFCISLLRERFMECL-MIGRDLVRLLQNVARIPEFELLWKDIIHNPQALSPQFTGILQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRF---GQQKRYQDWFQRQYLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFSPEKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPNFYPPLEGHVRQGVFSSLNHIVEKRVLAHLAPL 474

HSP 2 Score: 180.644 bits (457), Expect = 1.230e-45
Identity = 129/385 (33.51%), Postives = 222/385 (57.66%), Query Frame = 1

Query: 2062 EKMEKVVIAILNDDNFDDLGIAGKTAAVICEICYPFFDRKLFPEDPDEEKLKASLSSPVFVLFRNICSMSTQDNKREXXXXXXSEMQMRQPRVGXXXXXXXKVAYATDPDLSTYRSLCNSLEKPNLKNSLFKDLELLSNDDSKLMVYLLPGLYTAFSTEMVGSPKFAHLIISSLDAAEINELGLQIQKKNLVMFDSNSVVEILKDSLDWGTIEQYFLWELLLAHNISSKHFYGLIPYLDFKKHPEAILRFSNFLRQEKPNYELIKLLLNREVERGDQFTSTLLHFWSSESNSTTSKFVSILHTIISASLGNNMKDKKKNRHSQFAEEGGVDLIKILGHLDFMRLNCKNI--SFLQEESIQSDLQQVLNSKSMLDDIKSRFSELLA 3210
            E M+++V  +L +D FD   ++   A+ + E+    F  ++ PE+  EE L+ S+  P++++FRN+C M   ++   LLL LLSE+  +QP++GY+LLYYL+ + A    ++ Y S   + +  +L   L  D++    DD +L+ +L P +YT F  E + S +  ++I++ +D+A++ EL   +   NLVMF  +SV+ IL  SLDW T EQY  W+L LAHNI  +    ++ +L +K+HPEA+      LR+EKP+ E++K++L+R     DQFT+++L  W  + +   ++ +  L  +I     N++  K+++  S  ++   + L +IL HLD +RLN  N   +F  +  I   LQ V    S  +  K +FS+L +
Sbjct:  595 EVMQEIVDQVLEED-FDSEQLS-VLASCLQELFKAHFRGEVLPEEVTEESLEESVGKPLYLIFRNLCQMQEDNSSFSLLLDLLSELYQKQPKIGYHLLYYLRASKAAAGKMNLYESFAQATQLGDLHTCLMMDMKACQEDDVRLLCHLTPSIYTEFPDETLRSGELLNMIVAVIDSAQLQELVCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYCAWQLFLAHNIPLETIIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPCHPDDQFTTSILRHWCMKHDELLAEHIKAL--LIK---NNSLPRKRQSLRSSSSKLAQLTLEQILEHLDNLRLNLANTKQNFFSQTPILQALQHV--QASCDEAHKMKFSDLFS 970

[Close]

BLAST of Integrator complex subunit 3 vs. Ensembl Mouse
Match: Ints3 (integrator complex subunit 3 [Source:MGI Symbol;Acc:MGI:2140050])

HSP 1 Score: 249.21 bits (635), Expect = 1.168e-67
Identity = 142/434 (32.72%), Postives = 235/434 (54.15%), Query Frame = 1

Query:  118 KNLSIIDESGEYVRSLKEDKALIINRGQSEEDNMRIQLGILYFLLTERSQTQFDFKDLILISRDGVKACSGHLITLISENWNRLNTDVRTNVLSILIDFISFPM--ADSLFMAIFKRMITGDLSQSNLWLIENMLNLIEEHKELLVKDKKLLPMIVYTYLRLIPTHYQFSIAMNTPNNNLARLCRKEIALVMDVIRNNFDECCKQVGRDLLFTLTQVSNIPEFNKLWSEMNSSLEKLSNQYTNIGEVFSMGTNKIVIATAIPFDMENWILWTMRNVHHCSTNPYKRYQDLFNKRFFSTVESQNLRPFLIRYIIRAFYPDNEMIGSTLISRWATISWLIVQASSPTVVANCKLALIYDWLFYDKQYDCIMDIEPAILAIMHNLTKYSHVSITLVDFLVKTANLYFPLVKDQIISCCRFGLNDAFRVSVFRSLAPL 1413
            + +SI+      V   + + AL     +    +  I LG+   +LTE +Q Q  ++DL L+SRDG+      +  L+ E + +L    RT ++ ++ + +   +  AD + M   K++  GD++  N+WL E++L+++ E +E ++K   L+ M VYTYLRLI  H+  +         L  L +KE+   + ++R  F EC   +GRDL+  L  V+ IPEF  LW ++  + + LS Q+T I ++    T++  +A  +  DME  +L+    V        KRYQD F +++ ST +SQ+LR  LIRYI    +P NE++ S ++ RWA I WL+   +S    +N KLAL YDWLF+  + D IM+IEPAIL + H++  +  ++ TL+DF+ +    ++P ++  +       LN      V   LAPL
Sbjct:   53 RCMSIVTSMTAGVSEREANDALNAYVCKGPPQHEEICLGLFTLVLTEPAQAQKCYRDLALVSRDGMNIVLNKINQLLMEKYLKLQDTCRTQLVWLVRELVKSGVLGADGVCMTFMKQIAGGDVTAKNIWLAESVLDILTEQREWVLKSSILIAMAVYTYLRLIVDHHGTA--------QLQTLRQKEVDFCISLLRERFMECL-MIGRDLVRLLQNVARIPEFELLWKDIIHNPQALSPQFTGILQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRF---GQQKRYQDWFQRQYLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFSPEKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPNFYPPLEGHVRQGVFSSLNHIVEKRVLAHLAPL 474

HSP 2 Score: 180.644 bits (457), Expect = 1.088e-45
Identity = 129/385 (33.51%), Postives = 222/385 (57.66%), Query Frame = 1

Query: 2062 EKMEKVVIAILNDDNFDDLGIAGKTAAVICEICYPFFDRKLFPEDPDEEKLKASLSSPVFVLFRNICSMSTQDNKREXXXXXXSEMQMRQPRVGXXXXXXXKVAYATDPDLSTYRSLCNSLEKPNLKNSLFKDLELLSNDDSKLMVYLLPGLYTAFSTEMVGSPKFAHLIISSLDAAEINELGLQIQKKNLVMFDSNSVVEILKDSLDWGTIEQYFLWELLLAHNISSKHFYGLIPYLDFKKHPEAILRFSNFLRQEKPNYELIKLLLNREVERGDQFTSTLLHFWSSESNSTTSKFVSILHTIISASLGNNMKDKKKNRHSQFAEEGGVDLIKILGHLDFMRLNCKNI--SFLQEESIQSDLQQVLNSKSMLDDIKSRFSELLA 3210
            E M+++V  +L +D FD   ++   A+ + E+    F  ++ PE+  EE L+ S+  P++++FRN+C M   ++   LLL LLSE+  +QP++GY+LLYYL+ + A    ++ Y S   + +  +L   L  D++    DD +L+ +L P +YT F  E + S +  ++I++ +D+A++ EL   +   NLVMF  +SV+ IL  SLDW T EQY  W+L LAHNI  +    ++ +L +K+HPEA+      LR+EKP+ E++K++L+R     DQFT+++L  W  + +   ++ +  L  +I     N++  K+++  S  ++   + L +IL HLD +RLN  N   +F  +  I   LQ V    S  +  K +FS+L +
Sbjct:  595 EVMQEIVDQVLEED-FDSEQLS-VLASCLQELFKAHFRGEVLPEEVTEESLEESVGKPLYLIFRNLCQMQEDNSSFSLLLDLLSELYQKQPKIGYHLLYYLRASKAAAGKMNLYESFAQATQLGDLHTCLMMDMKACQEDDVRLLCHLTPSIYTEFPDETLRSGELLNMIVAVIDSAQLQELVCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYCAWQLFLAHNIPLETIIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPCHPDDQFTTSILRHWCMKHDELLAEHIKAL--LIK---NNSLPRKRQSLRSSSSKLAQLTLEQILEHLDNLRLNLANTKQNFFSQTPILQALQHV--QASCDEAHKMKFSDLFS 970

[Close]

BLAST of Integrator complex subunit 3 vs. UniProt/SwissProt
Match: sp|Q7TPD0|INT3_MOUSE (Integrator complex subunit 3 OS=Mus musculus OX=10090 GN=Ints3 PE=1 SV=2)

HSP 1 Score: 249.21 bits (635), Expect = 7.991e-67
Identity = 142/434 (32.72%), Postives = 235/434 (54.15%), Query Frame = 1

Query:  118 KNLSIIDESGEYVRSLKEDKALIINRGQSEEDNMRIQLGILYFLLTERSQTQFDFKDLILISRDGVKACSGHLITLISENWNRLNTDVRTNVLSILIDFISFPM--ADSLFMAIFKRMITGDLSQSNLWLIENMLNLIEEHKELLVKDKKLLPMIVYTYLRLIPTHYQFSIAMNTPNNNLARLCRKEIALVMDVIRNNFDECCKQVGRDLLFTLTQVSNIPEFNKLWSEMNSSLEKLSNQYTNIGEVFSMGTNKIVIATAIPFDMENWILWTMRNVHHCSTNPYKRYQDLFNKRFFSTVESQNLRPFLIRYIIRAFYPDNEMIGSTLISRWATISWLIVQASSPTVVANCKLALIYDWLFYDKQYDCIMDIEPAILAIMHNLTKYSHVSITLVDFLVKTANLYFPLVKDQIISCCRFGLNDAFRVSVFRSLAPL 1413
            + +SI+      V   + + AL     +    +  I LG+   +LTE +Q Q  ++DL L+SRDG+      +  L+ E + +L    RT ++ ++ + +   +  AD + M   K++  GD++  N+WL E++L+++ E +E ++K   L+ M VYTYLRLI  H+  +         L  L +KE+   + ++R  F EC   +GRDL+  L  V+ IPEF  LW ++  + + LS Q+T I ++    T++  +A  +  DME  +L+    V        KRYQD F +++ ST +SQ+LR  LIRYI    +P NE++ S ++ RWA I WL+   +S    +N KLAL YDWLF+  + D IM+IEPAIL + H++  +  ++ TL+DF+ +    ++P ++  +       LN      V   LAPL
Sbjct:   53 RCMSIVTSMTAGVSEREANDALNAYVCKGPPQHEEICLGLFTLVLTEPAQAQKCYRDLALVSRDGMNIVLNKINQLLMEKYLKLQDTCRTQLVWLVRELVKSGVLGADGVCMTFMKQIAGGDVTAKNIWLAESVLDILTEQREWVLKSSILIAMAVYTYLRLIVDHHGTA--------QLQTLRQKEVDFCISLLRERFMECL-MIGRDLVRLLQNVARIPEFELLWKDIIHNPQALSPQFTGILQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRF---GQQKRYQDWFQRQYLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFSPEKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPNFYPPLEGHVRQGVFSSLNHIVEKRVLAHLAPL 474

HSP 2 Score: 180.644 bits (457), Expect = 8.601e-45
Identity = 129/385 (33.51%), Postives = 222/385 (57.66%), Query Frame = 1

Query: 2062 EKMEKVVIAILNDDNFDDLGIAGKTAAVICEICYPFFDRKLFPEDPDEEKLKASLSSPVFVLFRNICSMSTQDNKREXXXXXXSEMQMRQPRVGXXXXXXXKVAYATDPDLSTYRSLCNSLEKPNLKNSLFKDLELLSNDDSKLMVYLLPGLYTAFSTEMVGSPKFAHLIISSLDAAEINELGLQIQKKNLVMFDSNSVVEILKDSLDWGTIEQYFLWELLLAHNISSKHFYGLIPYLDFKKHPEAILRFSNFLRQEKPNYELIKLLLNREVERGDQFTSTLLHFWSSESNSTTSKFVSILHTIISASLGNNMKDKKKNRHSQFAEEGGVDLIKILGHLDFMRLNCKNI--SFLQEESIQSDLQQVLNSKSMLDDIKSRFSELLA 3210
            E M+++V  +L +D FD   ++   A+ + E+    F  ++ PE+  EE L+ S+  P++++FRN+C M   ++   LLL LLSE+  +QP++GY+LLYYL+ + A    ++ Y S   + +  +L   L  D++    DD +L+ +L P +YT F  E + S +  ++I++ +D+A++ EL   +   NLVMF  +SV+ IL  SLDW T EQY  W+L LAHNI  +    ++ +L +K+HPEA+      LR+EKP+ E++K++L+R     DQFT+++L  W  + +   ++ +  L  +I     N++  K+++  S  ++   + L +IL HLD +RLN  N   +F  +  I   LQ V    S  +  K +FS+L +
Sbjct:  595 EVMQEIVDQVLEED-FDSEQLS-VLASCLQELFKAHFRGEVLPEEVTEESLEESVGKPLYLIFRNLCQMQEDNSSFSLLLDLLSELYQKQPKIGYHLLYYLRASKAAAGKMNLYESFAQATQLGDLHTCLMMDMKACQEDDVRLLCHLTPSIYTEFPDETLRSGELLNMIVAVIDSAQLQELVCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYCAWQLFLAHNIPLETIIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPCHPDDQFTTSILRHWCMKHDELLAEHIKAL--LIK---NNSLPRKRQSLRSSSSKLAQLTLEQILEHLDNLRLNLANTKQNFFSQTPILQALQHV--QASCDEAHKMKFSDLFS 970

[Close]

BLAST of Integrator complex subunit 3 vs. UniProt/SwissProt
Match: sp|Q1LXC9|INT3_DANRE (Integrator complex subunit 3 OS=Danio rerio OX=7955 GN=ints3 PE=2 SV=1)

HSP 1 Score: 248.44 bits (633), Expect = 1.024e-66
Identity = 139/414 (33.57%), Postives = 230/414 (55.56%), Query Frame = 1

Query:  178 ALIINRGQSEEDNMRIQLGILYFLLTERSQTQFDFKDLILISRDGVKACSGHLITLISENWNRLNTDVRTNVLSILIDFISFPM--ADSLFMAIFKRMITGDLSQSNLWLIENMLNLIEEHKELLVKDKKLLPMIVYTYLRLIPTHYQFSIAMNTPNNNLARLCRKEIALVMDVIRNNFDECCKQVGRDLLFTLTQVSNIPEFNKLWSEMNSSLEKLSNQYTNIGEVFSMGTNKIVIATAIPFDMENWILWTMRNVHHCSTNPYKRYQDLFNKRFFSTVESQNLRPFLIRYIIRAFYPDNEMIGSTLISRWATISWLIVQASSPTVVANCKLALIYDWLFYDKQYDCIMDIEPAILAIMHNLTKYSHVSITLVDFLVKTANLYFPLVKDQIISCCRFGLNDAFRVSVFRSLAPL 1413
            AL  +  +  + +  + LG+   LLTE  Q Q  ++DL L++RDG+      +  ++ E + +L    RT ++ ++ + +   +  AD + M + K++  GD+S  NLWL EN+L+++ + +E ++K   L+ M +YTYLRLI  H            +L  L ++E+   + ++R  F EC   +GRDL+  L  V+ IPE   +W ++  S + LS Q+T I ++ +  T++  +A  +  DME  +L+    V        KRYQD F +++ ST ESQ+LR  LIRYI    +P NE++ S ++ RWA I WL+   +S    +N KLAL YDWLF++ + D IM+IEPAIL + H++  +  ++ TL+DF+ +    +FP ++ Q+       LN      V   LAPL
Sbjct:   52 ALTAHVCKGPQQHEEVCLGLFTLLLTEPPQAQRCYRDLTLVNRDGMNVVLMKINQILMEKFLKLQDVCRTQLVWLVRELVKSGVIGADGVLMTLMKQIAGGDISSKNLWLAENVLDILVDQREWVLKSGMLVAMSLYTYLRLIVDH---------GTTSLLPLRQREVDFCIGLLRERFMECFI-IGRDLVRLLQNVARIPEMELVWRDLLHSPQTLSPQFTGILQLLTSRTSRKFLACRLTPDMETKLLFMTSRVRF---GQQKRYQDWFQRQYLSTAESQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFNPEKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPHFFPPLEGQVRQGVFNSLNFIMEKRVLAHLAPL 452

HSP 2 Score: 187.963 bits (476), Expect = 3.213e-47
Identity = 135/387 (34.88%), Postives = 220/387 (56.85%), Query Frame = 1

Query: 2062 EKMEKVVIAILNDDNFDDLGIAGKTAAVICEICYPFFDRKLFPEDPDEEKLKASLSSPVFVLFRNICSMSTQDNKREXXXXXXSEMQMRQPRVGXXXXXXXKVAYATDPDLSTYRSLCNSLEKPNLKNSLFKDLELLSNDDSKLMVYLLPGLYTAFSTEMVGSPKFAHLIISSLDAAEINELGLQIQKKNLVMFDSNSVVEILKDSLDWGTIEQYFLWELLLAHNISSKHFYGLIPYLDFKKHPEAILRFSNFLRQEKPNYELIKLLLNREVERGDQFTSTLLHFWSSESNSTTSKFVSILHTIISASL--GNNMKDKKKNRHSQFAEEGGVDLIKILGHLDFMRLNCKNI--SFLQEESIQSDLQQVLNSKSMLDDIKSRFSELLA 3210
            E M+++V  IL +D FD   ++   A+ + E+    F   + PE+  EE L+ S+  PV ++FRN+C M   ++   +LL LL+E+  +QP++GY+LLYYLK + A    +S Y S   +    +L   L  D++    DD +L+ YL P +Y+ F  E + S +  ++I++ +D+A++ EL   +   NLVMF  +SV+ IL  SLDW T EQY  W+L LAH+I  +    ++ +L +K+HPEA+      LR+EKP+ E++K++L+R   + DQFT+++L  W       T+K   +L   I A L   NNM  K+++  S  ++   + L ++L HLD +RL+  N   +F  +  I   LQ V    S  +  K RFS+L +
Sbjct:  573 EVMQEIVDLILEED-FDSEQMS-TLASCLAELFKSHFRGDVLPEEITEESLEESVCKPVCLIFRNLCQMQEDNSGFSVLLDLLAELYQKQPKIGYHLLYYLKASKAASGKMSLYESFAQATALGDLHTCLMMDMKACQEDDVRLLCYLTPSIYSEFPDETLRSGELLNMIVAVIDSAQLQELMCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYSTWQLFLAHSIPLETIIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPYHQEDQFTTSILRHW-------TAKHDDLLGEHIKALLIKNNNMPRKRQSLRSSSSKLAQLTLEQMLEHLDSLRLSLSNTKNNFFSQTPILQALQHV--QASCDEAHKMRFSDLFS 948

[Close]

BLAST of Integrator complex subunit 3 vs. UniProt/SwissProt
Match: sp|Q5RE70|INT3_PONAB (Integrator complex subunit 3 OS=Pongo abelii OX=9601 GN=INTS3 PE=2 SV=1)

HSP 1 Score: 248.054 bits (632), Expect = 2.185e-66
Identity = 136/399 (34.09%), Postives = 222/399 (55.64%), Query Frame = 1

Query:  223 IQLGILYFLLTERSQTQFDFKDLILISRDGVKACSGHLITLISENWNRLNTDVRTNVLSILIDFISFPM--ADSLFMAIFKRMITGDLSQSNLWLIENMLNLIEEHKELLVKDKKLLPMIVYTYLRLIPTHYQFSIAMNTPNNNLARLCRKEIALVMDVIRNNFDECCKQVGRDLLFTLTQVSNIPEFNKLWSEMNSSLEKLSNQYTNIGEVFSMGTNKIVIATAIPFDMENWILWTMRNVHHCSTNPYKRYQDLFNKRFFSTVESQNLRPFLIRYIIRAFYPDNEMIGSTLISRWATISWLIVQASSPTVVANCKLALIYDWLFYDKQYDCIMDIEPAILAIMHNLTKYSHVSITLVDFLVKTANLYFPLVKDQIISCCRFGLNDAFRVSVFRSLAPL 1413
            I LG+   +LTE +Q Q  ++DL L+SRDG+      +  ++ E + +L    RT ++ ++ + +   +  AD + M   K++  GD++  N+WL E++L+++ E +E ++K   L+ M VYTYLRLI  H+  +         L  L +KE+   + ++R  F EC   +GRDL+  L  V+ IPEF  LW ++  + + LS Q+T I ++    T++  +A  +  DME  +L+    V        KRYQD F +++ ST +SQ+LR  LIRYI    +P NE++ S ++ RWA I WL+   +S    +N KLAL YDWLF+    D IM+IEPAIL + H++  +  ++ TL+DF+ +    ++P ++  +       LN      V   LAPL
Sbjct:   90 ICLGLFTLILTEPAQAQKCYRDLALVSRDGMNIVLNKINQILMEKYLKLQDTCRTQLVWLVRELVKSGVLGADGVCMTFMKQIAGGDVTAKNIWLAESVLDILTEQREWVLKSSILIAMAVYTYLRLIVDHHGTA--------QLQALRQKEVDFCISLLRERFMECL-MIGRDLVRLLQNVARIPEFELLWKDIIHNPQALSPQFTGILQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRF---GQQKRYQDWFQRQYLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTACTSNVAASNAKLALFYDWLFFSPDKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPNFYPPLEGHVRQGVFSSLNHIVEKRVLAHLAPL 476

HSP 2 Score: 179.489 bits (454), Expect = 1.959e-44
Identity = 129/385 (33.51%), Postives = 222/385 (57.66%), Query Frame = 1

Query: 2062 EKMEKVVIAILNDDNFDDLGIAGKTAAVICEICYPFFDRKLFPEDPDEEKLKASLSSPVFVLFRNICSMSTQDNKREXXXXXXSEMQMRQPRVGXXXXXXXKVAYATDPDLSTYRSLCNSLEKPNLKNSLFKDLELLSNDDSKLMVYLLPGLYTAFSTEMVGSPKFAHLIISSLDAAEINELGLQIQKKNLVMFDSNSVVEILKDSLDWGTIEQYFLWELLLAHNISSKHFYGLIPYLDFKKHPEAILRFSNFLRQEKPNYELIKLLLNREVERGDQFTSTLLHFWSSESNSTTSKFVSILHTIISASLGNNMKDKKKNRHSQFAEEGGVDLIKILGHLDFMRLNCKNI--SFLQEESIQSDLQQVLNSKSMLDDIKSRFSELLA 3210
            E M+++V  +L +D FD   ++   A+ + E+    F  ++ PE+  EE L+ S+  P++++FRN+C M   ++   LLL LLSE+  +QP++GY+LLYYL+ + A    ++ Y S   + +  +L   L  D++    DD +L+ +L P +YT F  E + S +  ++I++ +D+A++ EL   +   NLVMF  +SV+ IL  SLDW T EQY  W+L LAHNI  +    ++ +L +K+HPEA+      LR+EKP+ E++K++L+R     DQFT+++L  W  + +   ++ +  L  +I     N++  K+++  S  ++   + L +IL HLD +RLN  N   +F  +  I   LQ V    S  +  K +FS+L +
Sbjct:  597 EVMQEIVDQVLEED-FDSEQLSV-LASCLQELFKAHFRGEVLPEEITEESLEESVGKPLYLIFRNLCQMQEDNSSFSLLLDLLSELYQKQPKIGYHLLYYLRASKAAAGKMNLYESFAQATQLGDLHTCLMMDMKACQEDDVRLLCHLTPSIYTEFPDETLRSGELLNMIVAVIDSAQLQELVCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYCAWQLFLAHNIPLETIIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPCHPDDQFTTSILRHWCMKHDELLAERIKSL--LIK---NNSLPRKRQSLRSSSSKLAQLTLEQILEHLDNLRLNLTNTKQNFFSQTPILQALQHV--QASCDEAHKMKFSDLFS 972

[Close]

BLAST of Integrator complex subunit 3 vs. UniProt/SwissProt
Match: sp|Q68E01|INT3_HUMAN (Integrator complex subunit 3 OS=Homo sapiens OX=9606 GN=INTS3 PE=1 SV=1)

HSP 1 Score: 242.662 bits (618), Expect = 1.313e-64
Identity = 136/400 (34.00%), Postives = 222/400 (55.50%), Query Frame = 1

Query:  223 IQLGILYFLLTERSQTQFDFKDLILISRDGVKACSGHLITLISENWNRLNTDVRTNVLSILIDFISFPM--ADSLFMAIFKRMITG-DLSQSNLWLIENMLNLIEEHKELLVKDKKLLPMIVYTYLRLIPTHYQFSIAMNTPNNNLARLCRKEIALVMDVIRNNFDECCKQVGRDLLFTLTQVSNIPEFNKLWSEMNSSLEKLSNQYTNIGEVFSMGTNKIVIATAIPFDMENWILWTMRNVHHCSTNPYKRYQDLFNKRFFSTVESQNLRPFLIRYIIRAFYPDNEMIGSTLISRWATISWLIVQASSPTVVANCKLALIYDWLFYDKQYDCIMDIEPAILAIMHNLTKYSHVSITLVDFLVKTANLYFPLVKDQIISCCRFGLNDAFRVSVFRSLAPL 1413
            I LG+   +LTE +Q Q  ++DL L+SRDG+      +  ++ E + +L    RT ++ ++ + +   +  AD + M   K++  G D++  N+WL E++L+++ E +E ++K   L+ M VYTYLRLI  H+  +         L  L +KE+   + ++R  F EC   +GRDL+  L  V+ IPEF  LW ++  + + LS Q+T I ++    T++  +A  +  DME  +L+    V        KRYQD F +++ ST +SQ+LR  LIRYI    +P NE++ S ++ RWA I WL+   +S    +N KLAL YDWLF+    D IM+IEPAIL + H++  +  ++ TL+DF+ +    ++P ++  +       LN      V   LAPL
Sbjct:   89 ICLGLFTLILTEPAQAQKCYRDLALVSRDGMNIVLNKINQILMEKYLKLQDTCRTQLVWLVRELVKSGVLGADGVCMTFMKQIAGGGDVTAKNIWLAESVLDILTEQREWVLKSSILIAMAVYTYLRLIVDHHGTA--------QLQALRQKEVDFCISLLRERFMECL-MIGRDLVRLLQNVARIPEFELLWKDIIHNPQALSPQFTGILQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRF---GQQKRYQDWFQRQYLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFSPDKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPNFYPPLEGHVRQGVFSSLNHIVEKRVLAHLAPL 476

HSP 2 Score: 179.874 bits (455), Expect = 1.395e-44
Identity = 129/385 (33.51%), Postives = 222/385 (57.66%), Query Frame = 1

Query: 2062 EKMEKVVIAILNDDNFDDLGIAGKTAAVICEICYPFFDRKLFPEDPDEEKLKASLSSPVFVLFRNICSMSTQDNKREXXXXXXSEMQMRQPRVGXXXXXXXKVAYATDPDLSTYRSLCNSLEKPNLKNSLFKDLELLSNDDSKLMVYLLPGLYTAFSTEMVGSPKFAHLIISSLDAAEINELGLQIQKKNLVMFDSNSVVEILKDSLDWGTIEQYFLWELLLAHNISSKHFYGLIPYLDFKKHPEAILRFSNFLRQEKPNYELIKLLLNREVERGDQFTSTLLHFWSSESNSTTSKFVSILHTIISASLGNNMKDKKKNRHSQFAEEGGVDLIKILGHLDFMRLNCKNI--SFLQEESIQSDLQQVLNSKSMLDDIKSRFSELLA 3210
            E M+++V  +L +D FD   ++   A+ + E+    F  ++ PE+  EE L+ S+  P++++FRN+C M   ++   LLL LLSE+  +QP++GY+LLYYL+ + A    ++ Y S   + +  +L   L  D++    DD +L+ +L P +YT F  E + S +  ++I++ +D+A++ EL   +   NLVMF  +SV+ IL  SLDW T EQY  W+L LAHNI  +    ++ +L +K+HPEA+      LR+EKP+ E++K++L+R     DQFT+++L  W  + +   ++ +  L  +I     N++  K+++  S  ++   + L +IL HLD +RLN  N   +F  +  I   LQ V    S  +  K +FS+L +
Sbjct:  597 EVMQEIVDQVLEED-FDSEQLS-VLASCLQELFKAHFRGEVLPEEITEESLEESVGKPLYLIFRNLCQMQEDNSSFSLLLDLLSELYQKQPKIGYHLLYYLRASKAAAGKMNLYESFAQATQLGDLHTCLMMDMKACQEDDVRLLCHLTPSIYTEFPDETLRSGELLNMIVAVIDSAQLQELVCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYCAWQLFLAHNIPLETIIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPCHPDDQFTTSILRHWCMKHDELLAEHIKSL--LIK---NNSLPRKRQSLRSSSSKLAQLTLEQILEHLDNLRLNLTNTKQNFFSQTPILQALQHV--QASCDEAHKMKFSDLFS 972

[Close]

BLAST of Integrator complex subunit 3 vs. UniProt/SwissProt
Match: sp|Q7PRB8|INT3_ANOGA (Integrator complex subunit 3 homolog OS=Anopheles gambiae OX=7165 GN=AGAP002539 PE=3 SV=5)

HSP 1 Score: 239.195 bits (609), Expect = 2.210e-63
Identity = 135/407 (33.17%), Postives = 226/407 (55.53%), Query Frame = 1

Query:  205 EEDNMRIQLGILYFLLTERSQTQFDFKDLILISRDGVKACSGHLITLISENWNRLNTDVRTNVLSILIDFISFPM--ADSLFMAIFKRMITGDLSQSNLWLIENMLNLIEEHKELLVKDKKLLPMIVYTYLRLIPTHYQFSIAMNTPNNNLARLCRKEIALVMDVIRNNFDECCKQVGRDLLFTLTQVSNIPEFNKLWSEMNSSLEKLSNQYTNIGEVFSMGTNKIVIATAIPFDMENWILWTMRNVHHCSTNPYKRYQDLFNKRFFSTVESQNLRPFLIRYIIRAFYPDNEMIGSTLISRWATISWLIVQASSPTVVANCKLALIYDWLFYDKQYDCIMDIEPAILAIMHNLTKYSHVSITLVDFLVKTANLYFPLVKDQIISCCRFGLNDAFRVSVFRSLAPLHE 1419
            E+ +  I L ++Y +LT+ S     ++DL L++RDG+   + +L  L++E +++L    R  +L +L + I   +   D+L   I ++   GD+S  N+ LIE +L++  EH+  L KD+ L+  + YT++RLI  H+               L  +E+  V+ +IR+ F +    +GR+ +  L  V  IPEF++LW +M  + + L   +  + ++    T++  +   +  D+E  I +   NV   +    KRYQD F +R+F+T ESQ+LR  LIR+II A +P N+M+ S +I RWA I WL+   ++   +AN KLAL YDWLF+D   D IM++EP IL + H++  +  VS TL+DFL +    ++P  +D+I +     L     + V  +L PL E
Sbjct:   60 EKQHEEISLALVYIILTDPSSAPKTYRDLTLLTRDGLGFVTANLAMLVAEKYHKLTDVGRKQLLWLLRELIKNQVLNVDNLAWNILRQASGGDISPKNVALIEGLLDIFTEHRAWLEKDQFLVGTVAYTFVRLIEDHF---------GPQFVHLRNREVKFVISLIRDRFMDIIP-LGREFVRLLQNVGRIPEFDQLWKDMLYNPKSLCPTFNGVWQLLQTRTSRRFLRGRLTPDIERKIHFLTSNVKFGNQ---KRYQDWFQERYFNTPESQSLRCDLIRFIISAIHPTNDMLCSDIIPRWAIIGWLLTSCTNAVTLANAKLALFYDWLFFDPAKDNIMNVEPGILVMYHSIKNHPLVSCTLLDFLCRIMKNFYPKWEDRIRTGIYNSLRKILEMKVIPNLVPLFE 453

HSP 2 Score: 148.288 bits (373), Expect = 9.653e-35
Identity = 116/419 (27.68%), Postives = 208/419 (49.64%), Query Frame = 1

Query: 2134 TAAVICEICYPFFDRKLFPEDPDEEKLKASLSSPVFVLFRNICSMSTQDNKREXXXXXXSEMQMRQPRVGXXXXXXXKV------------AYATDPDLSTYRSLCNSLEK-PNLKNSLFKDLELLSNDDSKLMVYLLPGLYTAFSTEMVGSPKFAHLIISSLDAAEINELGLQIQKKNLVMFDSNSVVEILKDSLDWGTIEQYFLWELLLAHNISSKHFYGLIPYLDFKKHPEAILRFSNFLRQEKPNYELIKLLLNREVE---RGDQFTSTLLHFWSSESNSTTSKFVSILHTIISASLGNNMKDKKKNRHSQFAEEGGVDLIKILGHLDFMRLNCKN-----ISFLQEESIQSDLQQVLNSKSMLDDIKSRFSELLAXXXXXXXXXXXXXXXXXKNTSTGRVLRNLDSRRYPSDKK 3327
            T +VI  I     D+  FP    ++ L  S++ P+F  +R +     +D+ ++ ++ LL  +  R    GY LLY+LKV              +T    S Y  LC++L+   ++   + KDL LL   ++++ +++LP +Y  F   M+ +     L++  +DA  + ++   I +  L++FD + +VEIL+ SL++ T EQ  +W+L+ AH+I  + F  +IP L+   H EA+      LR EKP  EL++LLL+RE E   RGD F +++L +W  E     S+ ++ L   +++   +N  +K+K       +       ++L HL+  R +C++          +  +Q  LQQ     S  +  + +FS+L A   E++            +T+ GR   +   R+ PS+KK
Sbjct:  628 TESVISVIKQTLPDKSYFPASKTDDNLSESINYPLFAAYRLL--YQQEDSCKKRVMALLVAIVTRVSVAGYMLLYFLKVHGKLQGRRKETAGGSTAFKASVYGVLCDALDSVDSVDECIEKDLNLLEKHNTQMFLWILPDMYREFKQTMLNNTTVLRLLVGCIDANNLGDIIYSITQGKLILFDEDGIVEILRKSLEYETFEQVCIWQLVQAHDIPLETFQEIIPELESGAHAEALTAILLLLRAEKPTTELVRLLLSRETESKHRGDPFVTSVLRYWCQEFEEKLSELIAAL---LTSKYPSNSPNKRKRPSKSAQQNTAPTSEQLLNHLEHFRRSCRHGNGTGTGLFVQNDMQRALQQAFTHSS--ESQRKQFSDLFALAAEDET-----------STTVGRRGTSSRGRKAPSNKK 1028

[Close]

BLAST of Integrator complex subunit 3 vs. TrEMBL
Match: A0A2P1E6J6 (Integrator complex subunit 3-like protein (Fragment) OS=Schmidtea mediterranea OX=79327 GN=ints3 PE=2 SV=1)

HSP 1 Score: 1503.8 bits (3892), Expect = 0.000e+0
Identity = 769/772 (99.61%), Postives = 770/772 (99.74%), Query Frame = 1

Query:  721 KQVGRDLLFTLTQVSNIPEFNKLWSEMNSSLEKLSNQYTNIGEVFSMGTNKIVIATAIPFDMENWILWTMRNVHHCSTNPYKRYQDLFNKRFFSTVESQNLRPFLIRYIIRAFYPDNEMIGSTLISRWATISWLIVQASSPTVVANCKLALIYDWLFYDKQYDCIMDIEPAILAIMHNLTKYSHVSITLVDFLVKTANLYFPLVKDQIISCCRFGLNDAFRVSVFRSLAPLHEVLRHHIELYKQFLELIGDTSNVYPQIPLNNVPIPKPVEXXXXXXXXXXXXXXXXXXXXXQRERNGTPKTLSPVNKEKPVEHINKIVVTSKINNAPKSALFDNKPVVDLTISDTEPTQTEDISFDDLKRRFMKYSLTFDYNVERIDIPSTICQINSSVAPDLERLYETAENCRSLIVKNKGKRDNKKSVKRGQKRLDTIDDSELSG--DEENLQHLYEKMEKVVIAILNDDNFDDLGIAGKTAAVICEICYPFFDRKLFPEDPDEEKLKASLSSPVFVLFRNICSMSTQDNKREXXXXXXSEMQMRQPRVGXXXXXXXKVAYATDPDLSTYRSLCNSLEKPNLKNSLFKDLELLSNDDSKLMVYLLPGLYTAFSTEMVGSPKFAHLIISSLDAAEINELGLQIQKKNLVMFDSNSVVEILKDSLDWGTIEQYFLWELLLAHNISSKHFYGLIPYLDFKKHPEAILRFSNFLRQEKPNYELIKLLLNREVERGDQFTSTLLHFWSSESNSTTSKFVSILHTIISASLGNNMKDKKKNRHSQ 3030
            KQVGRDLLFTLTQVSNIPEFNKLWSEMNSSLEKLSNQYTNIGEVFSMGTNKIVIATAIPFDMENWILWTMRNVHHCSTNPYKRYQDLFNKRFFSTVESQNLRPFLIRYIIRAFYPDNEMIGSTLISRWATISWLIVQASSPTVVANCKLALIYDWLFYDKQYDCIMDIEPAILAIMHNLTKYSHVSITLVDFLVKTANLYFPLVKDQIISCCRFGLNDAFRVSVFRSLAPLHEVLRHHIELYKQF+ELIGDTSNVYPQIPLNNVPIPKPVENVIATVNPVNNPVAPAPEVVVQRERNGTPKTLSPVNKEKPVEHINKIVVTSKINNAPKSALFDNKPVVDLTISDTEPTQTEDISFDDLKRRFMKYSLTFDYNVERIDIPSTICQINSSVAPDLERLYETAENCRSLIVKNKGKRDNKKSVKRGQKRLDTIDDSELSG  DEENLQHLYEKMEKVVIAILNDDNFDDLGIAGKTAAVICEICYPFFDRKLFPEDPDEEKLKASLSSPVFVLFRNICSMSTQDNKRELLLLLLSEMQMRQPRVGYYLLYYLKVAYATDPDLSTYRSLCNSLEKPNLKNSLFKDLELLSNDDSKLMVYLLPGLYTAFSTEMVGSPKFAHLIISSLDAAEINELGLQIQKKNLVMFDSNSVVEILKDSLDWGTIEQYFLWELLLAHNISSKHFYGLIPYLDFKKHPEAILRFSNFLRQEKPNYELIKLLLNREVERGDQFTSTLLHFWSSESNSTTSKFVSILHTIISASLGNNMKDKKKNRHSQ
Sbjct:    1 KQVGRDLLFTLTQVSNIPEFNKLWSEMNSSLEKLSNQYTNIGEVFSMGTNKIVIATAIPFDMENWILWTMRNVHHCSTNPYKRYQDLFNKRFFSTVESQNLRPFLIRYIIRAFYPDNEMIGSTLISRWATISWLIVQASSPTVVANCKLALIYDWLFYDKQYDCIMDIEPAILAIMHNLTKYSHVSITLVDFLVKTANLYFPLVKDQIISCCRFGLNDAFRVSVFRSLAPLHEVLRHHIELYKQFVELIGDTSNVYPQIPLNNVPIPKPVENVIATVNPVNNPVAPAPEVVVQRERNGTPKTLSPVNKEKPVEHINKIVVTSKINNAPKSALFDNKPVVDLTISDTEPTQTEDISFDDLKRRFMKYSLTFDYNVERIDIPSTICQINSSVAPDLERLYETAENCRSLIVKNKGKRDNKKSVKRGQKRLDTIDDSELSGGSDEENLQHLYEKMEKVVIAILNDDNFDDLGIAGKTAAVICEICYPFFDRKLFPEDPDEEKLKASLSSPVFVLFRNICSMSTQDNKRELLLLLLSEMQMRQPRVGYYLLYYLKVAYATDPDLSTYRSLCNSLEKPNLKNSLFKDLELLSNDDSKLMVYLLPGLYTAFSTEMVGSPKFAHLIISSLDAAEINELGLQIQKKNLVMFDSNSVVEILKDSLDWGTIEQYFLWELLLAHNISSKHFYGLIPYLDFKKHPEAILRFSNFLRQEKPNYELIKLLLNREVERGDQFTSTLLHFWSSESNSTTSKFVSILHTIISASLGNNMKDKKKNRHSQ 772

[Close]

BLAST of Integrator complex subunit 3 vs. TrEMBL
Match: A0A4Y2F9G1 (Integrator complex subunit 3 OS=Araneus ventricosus OX=182803 GN=Ints3_1 PE=4 SV=1)

HSP 1 Score: 414.846 bits (1065), Expect = 3.798e-123
Identity = 302/1014 (29.78%), Postives = 506/1014 (49.90%), Query Frame = 1

Query:  223 IQLGILYFLLTERSQTQFDFKDLILISRDGVKACSGHLITLISENWNRLNTDVRTNVLSILIDFI--SFPMADSLFMAIFKRMITGDLSQSNLWLIENMLNLIEEHKELLVKDKKLLPMIVYTYLRLIPTHYQFSIAMNTPNNNLARLCRKEIALVMDVIRNNFDECCKQVGRDLLFTLTQVSNIPEFNKLWSEMNSSLEKLSNQYTNIGEVFSMGTNKIVIATAIPFDMENWILWTMRNVHHCSTNPYKRYQDLFNKRFFSTVESQNLRPFLIRYIIRAFYPDNEMIGSTLISRWATISWLIVQASSPTVVANCKLALIYDWLFYDKQYDCIMDIEPAILAIMHNLTKYSHVSITLVDFLVK-TANLYFPLVKDQIISCCRFGLNDAFRVSVFRSLAPLHEVLRHHIELYKQFLELIGDTSNVYPQIPLNNVPIPKPVEXXXXXXXXXXXXXXXXXXXXXQRERNGTPKTLSP--VNKEKPVEHINKIVVT---SKINNAPKSALFDNKPVVDLTISDTEPTQTEDISFDDLKRRFMKYSLTFDYNVERIDIPSTICQINSSVAPDLERLYETAENCRSLIVKNKGKRDNKKSVKRGQKRLDTIDDSELSGDEENLQHLYEKMEKVVIAILNDDNFDDLGIAGKTAAVICEICYPFFDRKLFPEDPDEEKLKASLSSPVFVLFRNICSMSTQDNKREXXXXXXSEMQMRQPRVGXXXXXXXKVAYATDPDLSTYRSLCNSL----------EKPNLKNSLFKDLELLSNDDSKLMVYLLPGLYTAFSTEMVGSPKFAHLIISSLDAAEINELGLQIQKKNLVMFDSNSVVEILKDSLDWGTIEQYFLWELLLAHNISSKHFYGLIPYLDFKKHPEAILRFSNFLRQEKPNYELIKLLLNREVERGDQFTSTLLHFWSSESNSTTSKFVSILHTIISASLGNNMKDKKKNRHSQFAEEGGVDLIKILGHLDFMRLNCKNISFLQEESIQSDLQQVLNSKSMLDDIKSRFSELLA 3210
            + LG+L  +L E +     ++DL  ++RDG+     HL  +I + +N+L    R  V+ ++ + I  S    D L   + +++  GDLS  N+WL E++L++  E++  + K   L+  IVYTYLRLI  H              A L +KE+   + ++R  F EC   +GRDL+  L  V+ IPEF KLW ++ S+    +  +T + ++ +M T++  +   +  DME  I +    V        KRYQ+ F +++ ST ESQ LR  LIR+I    +P NE++ S +I RWA I WL+   +S    ++ KL+L YDWLF+D + D IM+IEPAIL I H++  +  ++ TL+DFL +   N   PL K  +       L       V  SL+PL                   D+S + P++ +                                  +   P+  SP  +  ++P++  + ++V    + +NN    A F          S+ E    +DI  + L+ R MK+    +  V++I I   I Q+N              +N +  IV  + ++D +   +  ++ L+ +              L E+ ++ V +IL                 + +I    F+RK+FP++ D+E ++ S+ +P+FV+FRN+C     D  R+ LL +L+EM M QPR+GY LLYYLK + A +  ++TY+   N+           E  +L  SL  DL++   DD ++  Y++P +Y  F +  VG+ K  +LI+S +D  ++ +L   + +KN++MF  +S + +L  SL+W + EQ+ LW+L+ A +I   +   ++P L+F  H EA++  +  L+QEKP  +L+K +++REV+  DQF  T+L +W+ E     ++ VS  H + S   G+ +K K++      A    VD  + L HLD +R+ CK  +F   + IQS L QV  S S  D  K++FS+L A
Sbjct:   64 VNLGLLINILIEPTTAARFYRDLTYLTRDGLNLVLNHLTQIILDKFNKLQEHCRNQVIWLIKEMIKNSVAGVDGLCFHLLRQIAGGDLSPKNVWLTESLLDIFLENRAWVEKFSILVATIVYTYLRLIVDHI---------GPKFAVLRQKEVDFCILLLRERFSEC-MMIGRDLVRLLLNVARIPEFEKLWRDIYSNPASFAPTFTGVAQLLAMRTSRRFLQCRLTPDMEKKIAFLTSQVKF---GHQKRYQEWFQRQYLSTPESQTLRCDLIRFICGVIHPSNEVLCSDIIPRWAVIGWLLTTCTSNVAASSAKLSLFYDWLFFDPEKDSIMNIEPAILVIYHSVRSHPVITATLLDFLCRIMPNFSLPL-KALVKQGIHTSLRQILVKRVLPSLSPLF------------------DSSKLDPELQI--------------------------------LLKETFPEFCSPSEIKVDEPLKDPSDLIVKTNHTSMNNTEHEAQF----------SEDE----DDIPLEKLRIRDMKFRPIRETKVDQIVITELIQQLN--------------DNIKQHIVGLQEEKDCETRCEVIERLLEAV--------------LQEEFDQDVTSIL--------------GVCLAQILSDEFNRKIFPDEIDDESIEDSIGTPLFVMFRNLCQTPEDDPNRQPLLNILAEMSMHQPRLGYLLLYYLKASKAQENRMTTYKDYVNTQGSWAPVTRNSESKDLATSLLNDLKICQEDDVRMFCYIIPDIYVQFQSIAVGNAKLLNLIVSCIDPTQLQDLICLLIQKNIIMFKKDSFLSVLNASLEWESFEQFCLWQLISAQSIPIDYILPVLPKLEFSAHSEALISIALLLKQEKPTADLLKHIMSREVKPNDQFAVTVLTYWAKEHEEVLAELVSS-HILKS---GSALKRKRQPNSKTLA--PTVD--QTLAHLDQLRITCKQNAFFNSDVIQSALLQVQASCS--DTQKTKFSDLFA 947

[Close]

BLAST of Integrator complex subunit 3 vs. TrEMBL
Match: A0A2D0S6G0 (integrator complex subunit 3 isoform X3 OS=Ictalurus punctatus OX=7998 GN=ints3 PE=4 SV=1)

HSP 1 Score: 410.609 bits (1054), Expect = 2.188e-121
Identity = 304/1016 (29.92%), Postives = 514/1016 (50.59%), Query Frame = 1

Query:  178 ALIINRGQSEEDNMRIQLGILYFLLTERSQTQFDFKDLILISRDGVKACSGHLITLISENWNRLNTDVRTNVLSILIDFISFPM--ADSLFMAIFKRMITGDLSQSNLWLIENMLNLIEEHKELLVKDKKLLPMIVYTYLRLIPTHYQFSIAMNTPNNNLARLCRKEIALVMDVIRNNFDECCKQVGRDLLFTLTQVSNIPEFNKLWSEMNSSLEKLSNQYTNIGEVFSMGTNKIVIATAIPFDMENWILWTMRNVHHCSTNPYKRYQDLFNKRFFSTVESQNLRPFLIRYIIRAFYPDNEMIGSTLISRWATISWLIVQASSPTVVANCKLALIYDWLFYDKQYDCIMDIEPAILAIMHNLTKYSHVSITLVDFLVKTANLYFPLVKDQIISCCRFGLNDAFRVSVFRSLAPLHEVLRHHIELYKQFLELIGDTSNVYPQIPLNNVPIPKPVEXXXXXXXXXXXXXXXXXXXXXQRERNGTPKTLSPVNKEKPVEHINKIVVTSKINNAPKSALFDNKPVVDLTISDTEPTQTEDISFDDLKRRFMKYSLTFDYNVERIDIPSTICQINSSVAPDLERLYETAENCRSLIVKNKGKRDNKKSVKRGQKRLDTIDDSELSGDEENLQHLYEKMEKVVIAILNDDNFDDLGIAGKTAAVICEICYPFFDRKLFPEDPDEEKLKASLSSPVFVLFRNICSMSTQDNKREXXXXXXSEMQMRQPRVGXXXXXXXKVAYATDPDLSTYRSLCNSLEKPNLKNSLFKDLELLSNDDSKLMVYLLPGLYTAFSTEMVGSPKFAHLIISSLDAAEINELGLQIQKKNLVMFDSNSVVEILKDSLDWGTIEQYFLWELLLAHNISSKHFYGLIPYLDFKKHPEAILRFSNFLRQEKPNYELIKLLLNREVERGDQFTSTLLHFWSSESNSTTSKFVSILHTIISASLGNNMKDKKKNRHSQFAEEGGVDLIKILGHLDFMRL---NCKNISFLQEESIQSDLQQVLNSKSMLDDIKSRFSELLA 3210
            AL  +  +  + +  + LG+   LLTE SQ Q  ++DL L++RDG+      +  ++ E + +L    RT ++ ++ + +   +  AD + M + K++  GD++  NLWL EN+L+++ E +E ++K   L+ M VYTYLRLI  H             L  L ++E+   + ++R  F EC   +GRDL+  L  V+ IPE   LW ++  + + LS QYT + ++ +  T++  +A  +  DME  +L+    V        KRYQD F +++ ST ESQ+LR  LIRYI    +P NE++ S ++ RWA I WL+   +S    +N KLAL YDWLF++ + D IM+IEPAIL + H++  +  ++ TL+DF+ +    +FP ++ Q+       LN      V   LAPL +  +   EL     E   +  N                                          + +P+T   + +  P+E  N ++         +   +DN    D T SD E    E+++    KR F      F +      I  T  +  S + P +++L ET              ++    +++G++R+      E S    + +   E M+++V  IL +D F+   ++   A+ + E+    F   + PE+  EE L+ S+  PV ++FRN+C M   ++   +LL +L+E+  +QP++GY+LLYYLK + A    +S Y S   +    +L   L  D++    DD +L+ YL P +YT F  E + S +  ++I++ +D+ ++ EL   +   NLVMF  +SV+ IL  SLDW T EQY  W+L LAH+I  +    ++ +L +K+HPEA+      LR+E P  E++K++L+R     DQFT+++L  W+++ +   ++ +  L  +I     NNM  K+++  S  ++   + L ++L HLD +RL   N KN  F Q   +Q+ LQ V    S  +  K RFS+L +
Sbjct:   52 ALTAHVCKGPQQHEEVCLGLFTLLLTEPSQAQRCYRDLTLVNRDGMNVILIKINQILMEKFLKLQEVCRTQLVWVVKELVKSGVIGADGVLMTLMKQIAGGDITSKNLWLAENVLDILVEQREWVLKSGMLVAMSVYTYLRLIVDH---------GTQGLLPLRQREVDFCIGLLRERFMECFI-IGRDLVRLLQNVARIPEMELLWRDLLHNPQSLSPQYTGLLQLLTSRTSRKFLACRLTPDMETKLLFMTSRVRF---GQQKRYQDWFQRQYLSTAESQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFNPEKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPHFFPPLEVQVRQGVFNSLNFIMEKRVLAHLAPLFDNPKLDRELRSMLRERFPEFCN------------------------------------------SPSPQTEVKMEESVPLEMDNHVL-------DKEDGCYDN---TDATFSDDE----EELNNKGKKREF-----RFQH------IKETYIEEPSDITPYVDQLDETL-------------KEKVLQLQKGRRRIKETYIEEPSDITPDTEAQCEVMQEIVDLILEED-FESEQMS-TLASCLAELFKSHFRGDVLPEEITEESLEESVCKPVCLIFRNLCQMQEDNSGFSVLLDMLAELYQKQPKIGYHLLYYLKASKAAAGKMSLYESFAQATALGDLHTCLMMDMKACQEDDVRLLCYLTPSIYTEFPDETLRSGELLNMIVAVIDSTQLQELMCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYSTWQLFLAHSIPLETIIPILQHLKYKEHPEALSCLLLQLRRESPTEEMVKMVLSRPCHPEDQFTTSILRHWAAKHDDQLAEHIKAL--LIK---NNNMPRKRQSLRSSSSKLAQLTLEQMLEHLDSLRLSLSNTKNNFFTQTPILQA-LQHV--QASCDEAHKMRFSDLFS 964

[Close]

BLAST of Integrator complex subunit 3 vs. TrEMBL
Match: W5UL55 (Integrator complex subunit 3 OS=Ictalurus punctatus OX=7998 GN=ints3 PE=2 SV=1)

HSP 1 Score: 409.838 bits (1052), Expect = 3.877e-121
Identity = 306/1016 (30.12%), Postives = 517/1016 (50.89%), Query Frame = 1

Query:  178 ALIINRGQSEEDNMRIQLGILYFLLTERSQTQFDFKDLILISRDGVKACSGHLITLISENWNRLNTDVRTNVLSILIDFISFPM--ADSLFMAIFKRMITGDLSQSNLWLIENMLNLIEEHKELLVKDKKLLPMIVYTYLRLIPTHYQFSIAMNTPNNNLARLCRKEIALVMDVIRNNFDECCKQVGRDLLFTLTQVSNIPEFNKLWSEMNSSLEKLSNQYTNIGEVFSMGTNKIVIATAIPFDMENWILWTMRNVHHCSTNPYKRYQDLFNKRFFSTVESQNLRPFLIRYIIRAFYPDNEMIGSTLISRWATISWLIVQASSPTVVANCKLALIYDWLFYDKQYDCIMDIEPAILAIMHNLTKYSHVSITLVDFLVKTANLYFPLVKDQIISCCRFGLNDAFRVSVFRSLAPLHEVLRHHIELYKQFLELIGDTSNVYPQIPLNNVPIPKPVEXXXXXXXXXXXXXXXXXXXXXQRERNGTPKTLSPVNKEKPVEHINKIVVTSKINNAPKSALFDNKPVVDLTISDTEPTQTEDISFDDLKRRFMKYSLTFDYNVERIDIPSTICQINSSVAPDLERLYETAENCRSLIVKNKGKRDNKKSVKRGQKRLDTIDDSELSGDEENLQHLYEKMEKVVIAILNDDNFDDLGIAGKTAAVICEICYPFFDRKLFPEDPDEEKLKASLSSPVFVLFRNICSMSTQDNKREXXXXXXSEMQMRQPRVGXXXXXXXKVAYATDPDLSTYRSLCNSLEKPNLKNSLFKDLELLSNDDSKLMVYLLPGLYTAFSTEMVGSPKFAHLIISSLDAAEINELGLQIQKKNLVMFDSNSVVEILKDSLDWGTIEQYFLWELLLAHNISSKHFYGLIPYLDFKKHPEAILRFSNFLRQEKPNYELIKLLLNREVERGDQFTSTLLHFWSSESNSTTSKFVSILHTIISASLGNNMKDKKKNRHSQFAEEGGVDLIKILGHLDFMRL---NCKNISFLQEESIQSDLQQVLNSKSMLDDIKSRFSELLA 3210
            AL  +  +  + +  + LG+   LLTE SQ Q  ++DL L++RDG+      +  ++ E + +L    RT ++ ++ + +   +  AD + M + K++  GD++  NLWL EN+L+++ E +E ++K   L+ M VYTYLRLI  H             L  L ++E+   + ++R  F EC   +GRDL+  L  V+ IPE   LW ++  + + LS QYT + ++ +  T++  +A  +  DME  +L+    V        KRYQD F +++ ST ESQ+LR  LIRYI    +P NE++ S ++ RWA I WL+   +S    +N KLAL YDWLF++ + D IM+IEPAIL + H++  +  ++ TL+DF+ +    +FP ++ Q+       LN      V   LAPL +  +   EL     E   +  N                                          + +P+T   + +  P+E  N ++         +   +DN    D T SD E    E+++    KR F      F +      I  T  +  S + P +++L ET +    ++   KG+R  +  ++         + S+++ D E      E M+++V  IL +D F+   ++   A+ + E+    F   + PE+  EE L+ S+  PV ++FRN+C M   ++   +LL +L+E+  +QP++GY+LLYYLK + A    +S Y S   +    +L   L  D++    DD +L+ YL P +YT F  E + S +  ++I++ +D+ ++ EL   +   NLVMF  +SV+ IL  SLDW T EQY  W+L LAH+I  +    ++ +L +K+HPEA+      LR+E P  E++K++L+R     DQFT+++L  W+++ +   ++ +  L  +I     NNM  K+++  S  ++   + L ++L HLD +RL   N KN  F Q   +Q+ LQ V    S  +  K RFS+L +
Sbjct:   52 ALTAHVCKGPQQHEEVCLGLFTLLLTEPSQAQRCYRDLTLVNRDGMNVILIKINQILMEKFLKLQEVCRTQLVWVVKELVKSGVIGADGVLMTLMKQIAGGDITSKNLWLAENVLDILVEQREWVLKSGMLVAMSVYTYLRLIVDH---------GTQGLLPLRQREVDFCIGLLRERFMECFI-IGRDLVRLLQNVARIPEMELLWRDLLHNPQSLSPQYTGLLQLLTSRTSRKFLACRLTPDMETKLLFMTSRVRF---GQQKRYQDWFQRQYLSTAESQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFNPEKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPHFFPPLEVQVRQGVFNSLNFIMEKRVLAHLAPLFDNPKLDRELRSMLRERFPEFCN------------------------------------------SPSPQTEVKMEESVPLEMDNHVL-------DKEDGCYDN---TDATFSDDE----EELNNKGKKREF-----RFQH------IKETYIEEPSDITPYVDQLDETLKE--KVLQLQKGRRIKETYIE---------EPSDITPDTEA---QCEVMQEIVDLILEED-FESEQMS-TLASCLAELFKSHFRGDVLPEEITEESLEESVCKPVCLIFRNLCQMQEDNSGFSVLLDMLAELYQKQPKIGYHLLYYLKASKAAAGKMSLYESFAQATALGDLHTCLMMDMKACQEDDVRLLCYLTPSIYTEFPDETLRSGELLNMIVAVIDSTQLQELMCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYSTWQLFLAHSIPLETIIPILQHLKYKEHPEALSCLLLQLRRESPTEEMVKMVLSRPCHPEDQFTTSILRHWAAKHDDQLAEHIKAL--LIK---NNNMPRKRQSLRSSSSKLAQLTLEQMLEHLDSLRLSLSNTKNNFFTQTPILQA-LQHV--QASCDEAHKMRFSDLFS 963

[Close]

BLAST of Integrator complex subunit 3 vs. TrEMBL
Match: A0A2D0S509 (integrator complex subunit 3 isoform X1 OS=Ictalurus punctatus OX=7998 GN=ints3 PE=4 SV=1)

HSP 1 Score: 406.757 bits (1044), Expect = 5.801e-120
Identity = 305/1022 (29.84%), Postives = 514/1022 (50.29%), Query Frame = 1

Query:  178 ALIINRGQSEEDNMRIQLGILYFLLTERSQTQFDFKDLILISRDGVKACSGHLITLISENWNRLNTDVRTNVLSILIDFISFPM--ADSLFMAIFKRMITGDLSQSNLWLIENMLNLIEEHKELLVKDKKLLPMIVYTYLRLIPTHYQFSIAMNTPNNNLARLCRKEIALVMDVIRNNFDECCKQVGRDLLFTLTQVSNIPEFNKLWSEMNSSLEKLSNQYTNIGEVFSMGTNKIVIATAIPFDMENWILWTMRNVHHCSTNPYKRYQDLFNKRFFSTVESQNLRPFLIRYIIRAFYPDNEMIGSTLISRWATISWLIVQASSPTVVANCKLALIYDWLFYDKQYDCIMDIEPAILAIMHNLTKYSHVSITLVDFLVKTANLYFPLVKDQIISCCRFGLNDAFRVSVFRSLAPLHEVLRHHIELYKQFLELIGDTSNVYPQIPLNNVPIPKPVEXXXXXXXXXXXXXXXXXXXXXQRERNGTPKTLSPVNKEKPVEHINKIVVTSKINNAPKSALFDNKPVVDLTISDTEPTQTEDISFDDLKRRFMKYSLTFDYNVERIDIPSTICQINSSVAPDLERLYETAENCRSLIVKNKGKRDNKKSVKRGQKRLDTIDDSELSGDEENLQHLYEKMEKVVIAILNDDNFDDLGIAGKTAAVICEICYPFFDRKLFPEDPDEEKLKASLSSPVFVLFRNICSMSTQDNKREXXXXXXSEMQMRQPRVGXXXXXXXKVAYATDPDLSTYRSLCNSLEKPNLKNSLFKDLELLSNDDSKLMVYLLPGLYTAFSTEMVGSPKFAHLIISSLDAAEINELGLQIQKKNLVMFDSNSVVEILKDSLDWGTIEQYFLWELLLAHNISSKHFYGLIPYLDFKKHPEAILRFSNFLRQEKPNYELIKLLLNREVERGDQFTSTLLHFWSSESNSTTSKFVSILHTIISASLGNNMKDKKKNRH------SQFAEEGGVDLIKILGHLDFMRL---NCKNISFLQEESIQSDLQQVLNSKSMLDDIKSRFSELLA 3210
            AL  +  +  + +  + LG+   LLTE SQ Q  ++DL L++RDG+      +  ++ E + +L    RT ++ ++ + +   +  AD + M + K++  GD++  NLWL EN+L+++ E +E ++K   L+ M VYTYLRLI  H             L  L ++E+   + ++R  F EC   +GRDL+  L  V+ IPE   LW ++  + + LS QYT + ++ +  T++  +A  +  DME  +L+    V        KRYQD F +++ ST ESQ+LR  LIRYI    +P NE++ S ++ RWA I WL+   +S    +N KLAL YDWLF++ + D IM+IEPAIL + H++  +  ++ TL+DF+ +    +FP ++ Q+       LN      V   LAPL +  +   EL     E   +  N                                          + +P+T   + +  P+E  N ++         +   +DN    D T SD E    E+++    KR F      F +      I  T  +  S + P +++L ET              ++    +++G++R+      E S    + +   E M+++V  IL +D F+   ++   A+ + E+    F   + PE+  EE L+ S+  PV ++FRN+C M   ++   +LL +L+E+  +QP++GY+LLYYLK + A    +S Y S   +    +L   L  D++    DD +L+ YL P +YT F  E + S +  ++I++ +D+ ++ EL   +   NLVMF  +SV+ IL  SLDW T EQY  W+L LAH+I  +    ++ +L +K+HPEA+      LR+E P  E++K++L+R     DQFT+++L  W+++ +   ++ +  L  +I     NNM  K++  H      S  ++   + L ++L HLD +RL   N KN  F Q   +Q+ LQ V    S  +  K RFS+L +
Sbjct:   52 ALTAHVCKGPQQHEEVCLGLFTLLLTEPSQAQRCYRDLTLVNRDGMNVILIKINQILMEKFLKLQEVCRTQLVWVVKELVKSGVIGADGVLMTLMKQIAGGDITSKNLWLAENVLDILVEQREWVLKSGMLVAMSVYTYLRLIVDH---------GTQGLLPLRQREVDFCIGLLRERFMECFI-IGRDLVRLLQNVARIPEMELLWRDLLHNPQSLSPQYTGLLQLLTSRTSRKFLACRLTPDMETKLLFMTSRVRF---GQQKRYQDWFQRQYLSTAESQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFNPEKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPHFFPPLEVQVRQGVFNSLNFIMEKRVLAHLAPLFDNPKLDRELRSMLRERFPEFCN------------------------------------------SPSPQTEVKMEESVPLEMDNHVL-------DKEDGCYDN---TDATFSDDE----EELNNKGKKREF-----RFQH------IKETYIEEPSDITPYVDQLDETL-------------KEKVLQLQKGRRRIKETYIEEPSDITPDTEAQCEVMQEIVDLILEED-FESEQMS-TLASCLAELFKSHFRGDVLPEEITEESLEESVCKPVCLIFRNLCQMQEDNSGFSVLLDMLAELYQKQPKIGYHLLYYLKASKAAAGKMSLYESFAQATALGDLHTCLMMDMKACQEDDVRLLCYLTPSIYTEFPDETLRSGELLNMIVAVIDSTQLQELMCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYSTWQLFLAHSIPLETIIPILQHLKYKEHPEALSCLLLQLRRESPTEEMVKMVLSRPCHPEDQFTTSILRHWAAKHDDQLAEHIKAL--LIK---NNNMPRKRQRYHHAKILRSSSSKLAQLTLEQMLEHLDSLRLSLSNTKNNFFTQTPILQA-LQHV--QASCDEAHKMRFSDLFS 970

[Close]

BLAST of Integrator complex subunit 3 vs. Ensembl Cavefish
Match: ints3 (integrator complex subunit 3 [Source:NCBI gene;Acc:560575])

HSP 1 Score: 401.749 bits (1031), Expect = 3.930e-122
Identity = 306/1016 (30.12%), Postives = 510/1016 (50.20%), Query Frame = 1

Query:  178 ALIINRGQSEEDNMRIQLGILYFLLTERSQTQFDFKDLILISRDGVKACSGHLITLISENWNRLNTDVRTNVLSILIDFISFPM--ADSLFMAIFKRMITGDLSQSNLWLIENMLNLIEEHKELLVKDKKLLPMIVYTYLRLIPTHYQFSIAMNTPNNNLARLCRKEIALVMDVIRNNFDECCKQVGRDLLFTLTQVSNIPEFNKLWSEMNSSLEKLSNQYTNIGEVFSMGTNKIVIATAIPFDMENWILWTMRNVHHCSTNPYKRYQDLFNKRFFSTVESQNLRPFLIRYIIRAFYPDNEMIGSTLISRWATISWLIVQASSPTVVANCKLALIYDWLFYDKQYDCIMDIEPAILAIMHNLTKYSHVSITLVDFLVKTANLYFPLVKDQIISCCRFGLNDAFRVSVFRSLAPLHEVLRHHIELYKQFLELIGDTSNVYPQIPLNNVPIPKPVEXXXXXXXXXXXXXXXXXXXXXQRERNGTPKTLSPVNKEKPVEHINKIVVTSKINNAPKSALFDNKPVVDLTISDTEPTQTEDISFDDLKRRFMKYSLTFDYNVERIDIPSTICQINSSVAPDLERLYETAENCRSLIVKNKGKRDNKKSVKRGQKRLDTIDDSELSGDEENLQHLYEKMEKVVIAILNDDNFDDLGIAGKTAAVICEICYPFFDRKLFPEDPDEEKLKASLSSPVFVLFRNICSMSTQDNKREXXXXXXSEMQMRQPRVGXXXXXXXKVAYATDPDLSTYRSLCNSLEKPNLKNSLFKDLELLSNDDSKLMVYLLPGLYTAFSTEMVGSPKFAHLIISSLDAAEINELGLQIQKKNLVMFDSNSVVEILKDSLDWGTIEQYFLWELLLAHNISSKHFYGLIPYLDFKKHPEAILRFSNFLRQEKPNYELIKLLLNREVERGDQFTSTLLHFWSSESNSTTSKFVSILHTIISASLGNNMKDKKKNRHSQFAEEGGVDLIKILGHLDFMRL---NCKNISFLQEESIQSDLQQVLNSKSMLDDIKSRFSELLA 3210
            AL  +  +  + +  + LG+   LLTE  Q Q  ++DL L++RDG+      +  ++ E + +L    RT ++ ++ + +   +  AD + M + K++  GD++  NLWL EN+L+++ E +E ++K   L+ M VYTYLRLI  H            +L  L ++E+   + ++R  F EC   +GRDL+  L  V+ IPE   LW ++  + + LS Q+T + ++ +  T++  +A  +  DME  +L+    V        KRYQD F +++ ST ESQ+LR  LIRYI    +P NE++ S ++ RWA I WL+   +S    +N KLAL YDWLF++ + D IM+IEPAIL + H++  +  ++ TL+DF+ +    +FP ++ Q+       LN      V   LAPL +  +   EL     E   +  +                                          + +P T   + +  P+E  N I+   K +N      +DN    D T SD E    E+++    KR F    +   Y    ID P+ I        P +++L ET                 K+ V + QK  DT    E+             M+++V  IL +D F+   ++   A+ + E+    F   + PE+  EE L+ S+  PV ++FRN+C M   ++   +LL +L+E+  +QP++GY+LLYYLK + A    +S Y S   +    +L   L  D++    DD +L+ YL P +Y+ F  E + S +  ++I++ +D+ ++ EL   +   NLVMF  +SV+ IL  SLDW T EQY  W+L LAH+I  +    ++ +L +K+HPEA+      LR+E P  E++K++L+R   + DQFT+++L  W+++ +    + +  L  +I     NNM  K+++  S  ++   + L ++L HLD +RL   N KN  F Q   +Q+ LQ V    S  +  K RFS+L +
Sbjct:    8 ALTAHVCKGPQQHEEVCLGLFTLLLTEPPQAQRCYRDLTLVNRDGMNVVLVKINQILMEKFLKLQDVCRTQLVWLVRELVKSGVIGADGVLMTLMKQIAGGDITNKNLWLAENVLDILVEQREWVLKSGMLVAMSVYTYLRLIVDH---------GTQSLLALRQREVDFCIGLLRERFMECFI-IGRDLVRLLQNVARIPEMELLWRDLLHNPQTLSPQFTGLLQLLTSRTSRKFLACRLTPDMETKLLFMTSRVRF---GQQKRYQDWFQRQYLSTAESQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFNPEKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPHFFPPLEGQVRQGVFNSLNFIMEKRVLAHLAPLFDNPKLDRELRSMLRERFPEFCS------------------------------------------SPSPPTEVKMEESVPLEMDNHIL--DKEDNC-----YDN---TDATFSDDE----EEVNNKGKKREFRFQQIKETY----IDEPADI-------TPYVDQLDETL----------------KEKVLQLQKGSDTETQCEV-------------MQEIVDLILEED-FESEQMSA-LASCLAELFKSHFRGDVLPEEITEESLEESVCKPVCLIFRNLCQMQEDNSGFSVLLDMLAELYQKQPKIGYHLLYYLKASKAAVGKMSLYESFAQATALGDLHTCLMMDMKACQEDDVRLLCYLTPSIYSEFPDETLRSGELLNMIVAVIDSTQLQELMCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYSTWQLFLAHSIPLETIIPILQHLKYKEHPEALSCLLLQLRRESPTEEMVKMVLSRPCHQEDQFTTSILRHWAAKHDDQLGEHIKAL--LIK---NNNMPRKRQSLRSSSSKLAQLTLEQMLEHLDCLRLSLSNTKNNFFTQTPILQA-LQHV--QASCDEAHKMRFSDLFS 904

[Close]

BLAST of Integrator complex subunit 3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009493.1 (pep scaffold:Pmarinus_7.0:GL478527:1630:39614:1 gene:ENSPMAG00000008569.1 transcript:ENSPMAT00000009493.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 233.032 bits (593), Expect = 2.920e-63
Identity = 132/399 (33.08%), Postives = 223/399 (55.89%), Query Frame = 1

Query:  229 LGILYFLLTERSQTQFDFKDLILISRDGVKACSGHLITLISENWNRLNTDVRTNVLSILIDFISFPM--ADSLFMAIFKRMITGDLSQSNLWLIENMLNLIEEHKELLVKDKKLLPMIVYTYLRLIPTHYQFSIAMNTPNNNLARLCRKEIALVMDVIRNNFDEC--CKQVGRDLLFTLTQVSNIPEFNKLWSEMNSSLEKLSNQYTNIGEVFSMGTNKIVIATAIPFDMENWILWTMRNVHHCSTNPYKRYQDLFNKRFFSTVESQNLRPFLIRYIIRAFYPDNEMIGSTLISRWATISWLIVQASSPTVVANCKLALIYDWLFYDKQYDCIMDIEPAILAIMHNLTKYSHVSITLVDFLVKTANLYFPLVKDQIISCCRFGLNDAFRVSVFRSLAPL 1413
            LG+   +LT+ +Q    ++DL L+SRDG+      +  L+ E + +++   R  ++ ++ + +   +  AD + M + K++  GD S  N+WL E +L+L+ +++E ++K+  L+ M VYT+LR+I  H   S A+ T       L +KE+   + ++R    +   C  +GRDL+  L  V+ IPE  KLW +M  + + LS Q+T I ++  M T++  +A  +  DME  +L+ M  V        KRYQD F +++ ST +SQ+LR  LIRYI    +P NE++ S ++ RWA I WL+   +S     N KL+L YDWLF+    D IM+IEPAIL + H++  +  ++ TL+DF+ +    ++P ++  +       L       V +SL+PL
Sbjct:   42 LGLTAIILTDPAQAARCYRDLTLVSRDGLGLVLAKVNQLLMEKFLKMHDVARNQLVWLVREVVKNGVIGADGVTMTLLKQIAGGDTSPKNIWLAETVLDLLTDYREWVLKNSLLVSMTVYTFLRIIVDH-NGSPALTT-------LRQKEVDFCITLLRERRAQFADCTMIGRDLVRLLQNVARIPEIEKLWRDMLHNPQSLSPQFTGILQLLQMRTSRKFLACRLTPDMETKLLFMMSKVRF---GQQKRYQDWFQRQYLSTPDSQSLRCDLIRYICGVVHPSNEVLCSDILPRWALIGWLLTTCTSNVAATNAKLSLFYDWLFFQPDKDSIMNIEPAILVMHHSMRPHPAITATLLDFMCRIMPNFYPPLESLVRQGVYSSLRSILEKRVLQSLSPL 429

HSP 2 Score: 187.963 bits (476), Expect = 7.426e-49
Identity = 128/393 (32.57%), Postives = 216/393 (54.96%), Query Frame = 1

Query: 2038 EENLQHLYEKMEKVVIAILNDDNFDDLGIAGKTAAVICEICYPFFDRKLFPEDPDEEKLKASLSSPVFVLFRNICSMSTQDNKREXXXXXXSEMQMRQPRVGXXXXXXXKVAYATDPDLSTYRSLCNSLEKPNLKNSLFKDLELLSNDDSKLMVYLLPGLYTAFSTEMVGSPKFAHLIISSLDAAEINELGLQIQKKNLVMFDSNSVVEILKDSLDWGTIEQYFLWELLLAHNISSKHFYGLIPYLDFKKHPEAILRFSNFLRQEKPNYELIKLLLNREVERGDQFTSTLLHFWSSESNSTTSKFVSILHTIISASLGNNMKDKKKNR-HSQFAEEGGVDLIKILGHLDFMRLNCK-NISFLQEESIQSDLQQVLNSKSMLDDIKSRFSELLA 3210
            E + +   E M+ +V  IL  D+FD   +A   A  + E+    F  ++ PE+  EE L+ S+  P++V+FRN+C     D+   +LL L+SE+  +QP++GY+LLYYL+ + A +   + Y S   S +  ++   L  D++    DD +L+ YL+P +YT F    +G+ +  ++I++++D+ ++ E+  Q+   NLVMF  +S + +L  SL W T EQY  W+L LAH I  +    ++ +L +K HPEA+      LR+EKP  E++KL+L+R   R D FT+++L  W+ +     ++ V       S  + NN   +K+    S  ++   + + ++L HLD +RL C    +F  +  I   LQ V    S  +  KSRFS+L A
Sbjct:  546 ESDTETQCEIMQAIVEVILQMDDFD-AEMACPLACCLIELFREQFHGEVLPEEITEESLEESVGKPIYVIFRNLCQFQEDDDGYSVLLTLMSELYQKQPKIGYHLLYYLQASKAAEGKTAVYESFAQSTQLGDIFTCLMLDMKACQEDDVRLLCYLVPPIYTKFDDVALGNSELLNMIVAAIDSLQLQEMVCQVMLGNLVMFRKDSALNVLTTSLQWETFEQYCTWQLFLAHGIPIETVVPILQHLKYKDHPEALSCLLLQLRREKPMEEMVKLVLSRPCHREDHFTTSILRHWAVKHEEILAEHVK------SLLIKNNTPPRKRQSLRSSSSKLTQLTVEQMLEHLDNLRLVCSPRQTFFAQTPILQALQHV--QASCDEGQKSRFSDLFA 929

[Close]

BLAST of Integrator complex subunit 3 vs. Ensembl Nematostella
Match: EDO31965 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWE7])

HSP 1 Score: 244.588 bits (623), Expect = 1.481e-67
Identity = 135/399 (33.83%), Postives = 222/399 (55.64%), Query Frame = 1

Query:  223 IQLGILYFLLTERSQTQFDFKDLILISRDGVKACSGHLITLISENWNRLNTDVRTNVLSILIDFI--SFPMADSLFMAIFKRMITGDLSQSNLWLIENMLNLIEEHKELLVKDKKLLPMIVYTYLRLIPTHYQFSIAMNTPNNNLARLCRKEIALVMDVIRNNFDECCKQVGRDLLFTLTQVSNIPEFNKLWSEMNSSLEKLSNQYTNIGEVFSMGTNKIVIATAIPFDMENWILWTMRNVHHCSTNPYKRYQDLFNKRFFSTVESQNLRPFLIRYIIRAFYPDNEMIGSTLISRWATISWLIVQASSPTVVANCKLALIYDWLFYDKQYDCIMDIEPAILAIMHNLTKYSHVSITLVDFLVKTANLYFPLVKDQIISCCRFGLNDAFRVSVFRSLAPL 1413
            + LG+LY +LT+ +     ++DL  I+RD +      +I  I++ + +L+   RT ++ +  +F+  S    + L  A+ ++++ GD+S  N+WL E+MLNL+  H+  L K+  LL   VY YLRLI  H         P  NL  +   E+   + ++R  F +C  Q+GRDL+  L  V  IPEF  LW +M    + LS Q+T + ++  + T++  +A  +  +MEN +L+    V        KRYQD F++ + S+ ES++L P LIR+I+   +P NE++ S +I RWA I WL+    +    AN KLAL YDWLFY    D IM+IEPAIL + H++  +  ++ TL+DF+ +  + + P ++ ++    R G     +  V  SL+P+
Sbjct:   55 VSLGLLYIILTDPAGAPKAYRDLSFITRDSLGMVIAKVIGNIADRFAKLHETARTQLIWLTSEFVKNSVIGTEGLCHALLRQIVGGDISPPNVWLTESMLNLLITHRTWLEKNSVLLATAVYCYLRLIHDHEA------APFKNLKAM---EVEFCISMLREKFSDCI-QIGRDLVRLLQSVGRIPEFQALWRDMLHKPQSLSPQFTGLSQLMRIRTSRKFLACRLTPEMENKMLFLTSKVKF---GQQKRYQDWFHRMYLSSPESRSLIPDLIRFIVGVVHPSNEVLCSDIIPRWAIIGWLLTSCQTAVASANSKLALFYDWLFYQPDKDNIMNIEPAILLMHHSIKSHPAITKTLLDFICRLMSSFCPSLEKEVRQGVRNGFRTIQKKKVVMSLSPV 440

HSP 2 Score: 110.538 bits (275), Expect = 1.509e-24
Identity = 70/245 (28.57%), Postives = 132/245 (53.88%), Query Frame = 1

Query: 2239 FVLFR-NICSMSTQDNKREXXXXXXSEMQMRQPRVGXXXXXXXKVAYATDPDLSTYRSLCN-SLEKPNLKNSLFKDLELLSNDDSKLMVYLLPGLYTAFSTEMVGSPKFAHLIISSLDAAEINELGLQIQKKNLVMFDSNSVVEILKDSLDWGTIEQYFLWELLLAHNISSKHFYGLIPYLDFKKHPEAILRFSNFLRQEKPNYELIKLLLNREV---ERGDQFTSTLLHFWSSESNSTTSKFVS 2958
            F++FR NIC++ T D  RE  L LLS +     +  Y+ L+YLK + + +  L+ Y    + S  + +L+  L +DL++    D +   +L+P +Y  FS  +VG  +  H+++ +++  ++NE   +I    LV+F    +  +++ +LDW + EQY +W+L+ A ++  +    ++P L  +KH EA+      ++   P+ +L+  +L  +      G+QFT  LL +WS E     ++ VS
Sbjct:  603 FLIFRRNICALPTHDVSRERFLTLLSALNDENNKFAYHFLFYLKASASDEERLTMYEDFASASRGERSLQGCLIEDLKVCQEYDPRAFRFLIPSIYRKFSEHVVGDSEVLHMLVCNMEPRQLNEFICEITMGELVIFGEEQLDSLIESTLDWESFEQYCVWQLIQAEDVLLESIVSILPQLHPEKHAEALANLLIIMKSVPPSVDLLTPVLEMDCSDKRPGNQFTCALLKYWSQEHARDLAQLVS 847

[Close]

BLAST of Integrator complex subunit 3 vs. Ensembl Medaka
Match: ints3 (integrator complex subunit 3 [Source:NCBI gene;Acc:101171678])

HSP 1 Score: 256.144 bits (653), Expect = 3.210e-70
Identity = 143/411 (34.79%), Postives = 234/411 (56.93%), Query Frame = 1

Query:  187 INRGQSEEDNMRIQLGILYFLLTERSQTQFDFKDLILISRDGVKACSGHLITLISENWNRLNTDVRTNVLSILIDFISFPM--ADSLFMAIFKRMITGDLSQSNLWLIENMLNLIEEHKELLVKDKKLLPMIVYTYLRLIPTHYQFSIAMNTPNNNLARLCRKEIALVMDVIRNNFDECCKQVGRDLLFTLTQVSNIPEFNKLWSEMNSSLEKLSNQYTNIGEVFSMGTNKIVIATAIPFDMENWILWTMRNVHHCSTNPYKRYQDLFNKRFFSTVESQNLRPFLIRYIIRAFYPDNEMIGSTLISRWATISWLIVQASSPTVVANCKLALIYDWLFYDKQYDCIMDIEPAILAIMHNLTKYSHVSITLVDFLVKTANLYFPLVKDQIISCCRFGLNDAFRVSVFRSLAPL 1413
            + +GQ + +   + LG+   +L E SQ Q  ++DL L++RDG+    G +  ++ E + +L    RT ++ ++ + +   +  AD + M + K++  GD+S  NLWL EN+L+++ + KE ++K   L+ M VYTYLRLI  H        +PN  L  L +KE+   + ++R  F EC + +GRDL+  L  V+ IPE   LW ++  + + LS Q+T I ++ +  T++  +A  +  DME  +L+    V        KRYQD F +++ ST ESQ+LR  LIRYI    +P NE++ S ++ RWA I WL+   +S    +N KLAL YDWLF++ + D IM+IEPAIL + H++  +  ++ TL+DF+ +    ++P ++ Q+       LN      V   LAPL
Sbjct:   57 VCKGQQQHEE--VCLGLFTLVLIEASQAQRCYRDLTLVNRDGMNVVLGKINQILMEKFLKLQDTPRTQLVWLVRELVKSGVIGADGVIMTLLKQIAGGDISTKNLWLAENVLDILLDQKEWVLKSGMLIAMSVYTYLRLIVDH-------GSPN--LLPLRQKEVDFCISMLREKFVEC-QIIGRDLVRLLQNVARIPEMELLWRDLLHNPQVLSPQFTGILQLLTARTSRKFLACRLTPDMETKLLFMTSRVRF---GQQKRYQDWFQRQYLSTAESQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFNPEKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIILHFYPPLESQVRQGVFNSLNFIMEKRVLAHLAPL 452

HSP 2 Score: 187.193 bits (474), Expect = 8.142e-48
Identity = 133/416 (31.97%), Postives = 229/416 (55.05%), Query Frame = 1

Query: 2002 LDTIDDSELSGDEENLQHLY---------EKMEKVVIAILNDDNFDDLGIAGKTAAVICEICYPFFDRKLFPEDPDEEKLKASLSSPVFVLFRNICSMSTQDNKREXXXXXXSEMQMRQPRVGXXXXXXXKVAYATDPDLSTYRSLCNSLEKPNLKNSLFKDLELLSNDDSKLMVYLLPGLYTAFSTEMVGSPKFAHLIISSLDAAEINELGLQIQKKNLVMFDSNSVVEILKDSLDWGTIEQYFLWELLLAHNISSKHFYGLIPYLDFKKHPEAILRFSNFLRQEKPNYELIKLLLNREVERGDQFTSTLLHFWSSESNSTTSKFVSILHTIISASL--GNNMKDKKKNRHSQFAEEGGVDLIKILGHLDFMRLNCKNI--SFLQEESIQSDLQQVLNSKSMLDDIKSRFSELLA 3210
            LD +DD+     +E +Q L          E M+++V  IL +D FD   ++   A+ + E+    F  ++ P++  EE L+ S+  P  ++FRN+ +M   ++   +LL +L+E+  +QP++GY+LLYYLK + A +  +  Y S   +    +L   L  D++    DD +L+ YL P +Y+ F  E + S +  ++I++ +D+ ++ EL   +   NLVMF  +SV+ IL  SL+W T EQY  W+L LAH+I  +    ++ ++ +K+HPEA+      LR+EKP+ E++K++LNR     DQFT+++L  W+ + + T ++        I A L   NN   K+++  S  ++   + L +IL H+D +RL+  N   +F  +  I   LQ V    S  +  K RFS+L A
Sbjct:  548 LDQLDDTM----KEKVQQLQKTSDTESQCEVMQEIVDLILEED-FDTEQMSA-LASCLSELFKEHFRGEVLPDEITEESLEESVCKPFCLIFRNLVTMQEDNSGFSVLLDMLAELYQKQPKIGYHLLYYLKASKAANGKMMLYESFAQATALGDLHTCLMMDMKACQEDDVRLLCYLTPSIYSEFPDETLRSGELLNMIVAVIDSTQLQELMCHVMMGNLVMFRKDSVLNILIQSLEWETFEQYSTWQLFLAHSIPLETIIPILQHVKYKEHPEALSCLLLQLRREKPSEEMVKMILNRPCHPEDQFTTSILRHWACKYDETLAEH-------IKAQLIKNNNQPRKRQSLRSSSSKLAQLTLEQILEHMDNLRLSLSNTKNNFFSQTPILQALQHV--QASCDEAHKMRFSDLFA 948

[Close]

BLAST of Integrator complex subunit 3 vs. Planmine SMEST
Match: SMESG000033343.1 (SMESG000033343.1)

HSP 1 Score: 2182.91 bits (5655), Expect = 0.000e+0
Identity = 1139/1142 (99.74%), Postives = 1140/1142 (99.82%), Query Frame = 1

Query:   64 MENNYRLGIIFNSIDAYPKNLSIIDESGEYVRSLKEDKALIINRGQSEEDNMRIQLGILYFLLTERSQTQFDFKDLILISRDGVKACSGHLITLISENWNRLNTDVRTNVLSILIDFISFPMADSLFMAIFKRMITGDLSQSNLWLIENMLNLIEEHKELLVKDKKLLPMIVYTYLRLIPTHYQFSIAMNTPNNNLARLCRKEIALVMDVIRNNFDECCKQVGRDLLFTLTQVSNIPEFNKLWSEMNSSLEKLSNQYTNIGEVFSMGTNKIVIATAIPFDMENWILWTMRNVHHCSTNPYKRYQDLFNKRFFSTVESQNLRPFLIRYIIRAFYPDNEMIGSTLISRWATISWLIVQASSPTVVANCKLALIYDWLFYDKQYDCIMDIEPAILAIMHNLTKYSHVSITLVDFLVKTANLYFPLVKDQIISCCRFGLNDAFRVSVFRSLAPLHEVLRHHIELYKQFLELIGDTSNVYPQIPLNNVPIPKPVEXXXXXXXXXXXXXXXXXXXXXQRERNGTPKTLSPVNKEKPVEHINKIVVTSKINNAPKSALFDNKPVVDLTISDTEPTQTEDISFDDLKRRFMKYSLTFDYNVERIDIPSTICQINSSVAPDLERLYETAENCRSLIVKNKGKRDNKKSVKRGQKRLDTIDDSELSG--DEENLQHLYEKMEKVVIAILNDDNFDDLGIAGKTAAVICEICYPFFDRKLFPEDPDEEKLKASLSSPVFVLFRNICSMSTQDNKREXXXXXXSEMQMRQPRVGXXXXXXXKVAYATDPDLSTYRSLCNSLEKPNLKNSLFKDLELLSNDDSKLMVYLLPGLYTAFSTEMVGSPKFAHLIISSLDAAEINELGLQIQKKNLVMFDSNSVVEILKDSLDWGTIEQYFLWELLLAHNISSKHFYGLIPYLDFKKHPEAILRFSNFLRQEKPNYELIKLLLNREVERGDQFTSTLLHFWSSESNSTTSKFVSILHTIISASLGNNMKDKKKNRHSQFAEEGGVDLIKILGHLDFMRLNCKNISFLQEESIQSDLQQVLNSKSMLDDIKSRFSELLAXXXXXXXXXXXXXXXXXKNTSTGRVLRNLDSRRYPSDKKTFEESNYHKSTTKRHLFNXXXXXXXXXXXXXXVNTRKTHYPCRSKRRLMIAD 3483
            MENNYRLGIIFNSIDAYPKNLSIIDESGEYVRSLKEDKALIINRGQSEEDNMRIQLGILYFLLTERSQTQFDFKDLILISRDGVKACSGHLITLISENWNRLNTDVRTNVLSILIDFISFPMADSLFMAIFKRMITGDLSQSNLWLIENMLNLIEEHKELLVKDKKLLPMIVYTYLRLIPTHYQFSIAMNTPNNNLARLCRKEIALVMDVIRNNFDECCKQVGRDLLFTLTQVSNIPEFNKLWSEMNSSLEKLSNQYTNIGEVFSMGTNKIVIATAIPFDMENWILWTMRNVHHCSTNPYKRYQDLFNKRFFSTVESQNLRPFLIRYIIRAFYPDNEMIGSTLISRWATISWLIVQASSPTVVANCKLALIYDWLFYDKQYDCIMDIEPAILAIMHNLTKYSHVSITLVDFLVKTANLYFPLVKDQIISCCRFGLNDAFRVSVFRSLAPLHEVLRHHIELYKQFLELIGDTSNVYPQIPLNNVPIPKPVENVIATVNPVNNPVAPAPEVVVQRERNGTPKTLSPVNKEKPVEHINKIVVTSKINNAPKSALFDNKPVVDLTISDTEPTQTEDISFDDLKRRFMKYSLTFDYNVERIDIPSTICQINSSVAPDLERLYETAENCRSLIVKNKGKRDNKKSVKRGQKRLDTIDDSELSG  DEENLQHLYEKMEKVVIAILNDDNFDDLGIAGKTAAVICEICYPFFDRKLFPEDPDEEKLKASLSSPVFVLFRNICSMSTQDNKRELLLLLLSEMQMRQPRVGYYLLYYLKVAYATDPDLSTYRSLCNSLEKPNLKNSLFKDLELLSNDDSKLMVYLLPGLYTAFSTEMVGSPKFAHLIISSLDAAEINELGLQIQKKNLVMFDSNSVVEILKDSLDWGTIEQYFLWELLLAHNISSKHFYGLIPYLDFKKHPEAILRFSNFLRQEKPNYELIKLLLNREVERGDQFTSTLLHFWSSESNSTTSKFVSILHTIISASLGNNMKDKKKNRHSQFAEEGGVDLIKILGHLDFMRLNCKNISFLQEESIQSDLQQVLNSKSMLDDIKSRFSELLAFVEEEDEDFSDDEN+NEKNTSTGRVLRNLDSRRYPSDKKTFEESNYHKSTTKRHLFNSPDSSSSEDESDTDVNTRKTHYPCRSKRRLMIAD
Sbjct:    1 MENNYRLGIIFNSIDAYPKNLSIIDESGEYVRSLKEDKALIINRGQSEEDNMRIQLGILYFLLTERSQTQFDFKDLILISRDGVKACSGHLITLISENWNRLNTDVRTNVLSILIDFISFPMADSLFMAIFKRMITGDLSQSNLWLIENMLNLIEEHKELLVKDKKLLPMIVYTYLRLIPTHYQFSIAMNTPNNNLARLCRKEIALVMDVIRNNFDECCKQVGRDLLFTLTQVSNIPEFNKLWSEMNSSLEKLSNQYTNIGEVFSMGTNKIVIATAIPFDMENWILWTMRNVHHCSTNPYKRYQDLFNKRFFSTVESQNLRPFLIRYIIRAFYPDNEMIGSTLISRWATISWLIVQASSPTVVANCKLALIYDWLFYDKQYDCIMDIEPAILAIMHNLTKYSHVSITLVDFLVKTANLYFPLVKDQIISCCRFGLNDAFRVSVFRSLAPLHEVLRHHIELYKQFLELIGDTSNVYPQIPLNNVPIPKPVENVIATVNPVNNPVAPAPEVVVQRERNGTPKTLSPVNKEKPVEHINKIVVTSKINNAPKSALFDNKPVVDLTISDTEPTQTEDISFDDLKRRFMKYSLTFDYNVERIDIPSTICQINSSVAPDLERLYETAENCRSLIVKNKGKRDNKKSVKRGQKRLDTIDDSELSGGSDEENLQHLYEKMEKVVIAILNDDNFDDLGIAGKTAAVICEICYPFFDRKLFPEDPDEEKLKASLSSPVFVLFRNICSMSTQDNKRELLLLLLSEMQMRQPRVGYYLLYYLKVAYATDPDLSTYRSLCNSLEKPNLKNSLFKDLELLSNDDSKLMVYLLPGLYTAFSTEMVGSPKFAHLIISSLDAAEINELGLQIQKKNLVMFDSNSVVEILKDSLDWGTIEQYFLWELLLAHNISSKHFYGLIPYLDFKKHPEAILRFSNFLRQEKPNYELIKLLLNREVERGDQFTSTLLHFWSSESNSTTSKFVSILHTIISASLGNNMKDKKKNRHSQFAEEGGVDLIKILGHLDFMRLNCKNISFLQEESIQSDLQQVLNSKSMLDDIKSRFSELLAFVEEEDEDFSDDENLNEKNTSTGRVLRNLDSRRYPSDKKTFEESNYHKSTTKRHLFNSPDSSSSEDESDTDVNTRKTHYPCRSKRRLMIAD 1142

[Close]

BLAST of Integrator complex subunit 3 vs. Planmine SMEST
Match: SMESG000033340.1 (SMESG000033340.1)

HSP 1 Score: 854.358 bits (2206), Expect = 0.000e+0
Identity = 413/444 (93.02%), Postives = 423/444 (95.27%), Query Frame = 1

Query:   64 MENNYRLGIIFNSIDAYPKNLSIIDESGEYVRSLKEDKALIINRGQSEEDNMRIQLGILYFLLTERSQTQFDFKDLILISRDGVKACSGHLITLISENWNRLNTDVRTNVLSILIDFISFPMADSLFMAIFKRMITGDLSQSNLWLIENMLNLIEEHKELLVKDKKLLPMIVYTYLRLIPTHYQFSIAMNTPNNNLARLCRKEIALVMDVIRNNFDECCKQVGRDLLFTLTQVSNIPEFNKLWSEMNSSLEKLSNQYTNIGEVFSMGTNKIVIATAIPFDMENWILWTMRNVHHCSTNPYKRYQDLFNKRFFSTVESQNLRPFLIRYIIRAFYPDNEMIGSTLISRWATISWLIVQASSPTVVANCKLALIYDWLFYDKQYDCIMDIEPAILAIMHNLTKYSHVSITLVDFLVKTANLYFPLVKDQIISCCRFGLNDAFRVSVF 1395
            MEN YR+GII NSID YP NLSI+DESGEYV S KEDKALIIN  QSEEDN+RIQLGILYFLLTERSQ QFDFKDLI ISRDG+K CS HLITLISENWNRLNTDVRTNVLSILIDFISFPMADSLFM IFKRMITGDLSQSNLWLIENMLNLIEEHKELLVKDKKLLPMIVYTYLRLIPTHYQFSIAMNTPNNNLARLCRKEIALVMDVIRNNFDECCKQVGR+LLF LTQVSNIPEFNKLWSEMNSSLEKLSNQYTNIGEVFSMGTNKIVIATAIPFDMENWILWTMRNVHHCSTNPYKRYQDLFNKRFFSTVESQNLRPFLIRYIIR F+PDNEMIGSTLISRWATISWLIVQASSPTVVANCKLALIYDWLFYDKQYDCIMDIEPAILAIMHNL   S +S+TLVDFLVKTANLYFPLVKDQ+I C R+GLNDAFRVSVF
Sbjct:    1 MENIYRIGIISNSIDVYPTNLSILDESGEYVHSFKEDKALIINPDQSEEDNIRIQLGILYFLLTERSQKQFDFKDLIFISRDGLKTCSDHLITLISENWNRLNTDVRTNVLSILIDFISFPMADSLFMTIFKRMITGDLSQSNLWLIENMLNLIEEHKELLVKDKKLLPMIVYTYLRLIPTHYQFSIAMNTPNNNLARLCRKEIALVMDVIRNNFDECCKQVGRNLLFALTQVSNIPEFNKLWSEMNSSLEKLSNQYTNIGEVFSMGTNKIVIATAIPFDMENWILWTMRNVHHCSTNPYKRYQDLFNKRFFSTVESQNLRPFLIRYIIRVFHPDNEMIGSTLISRWATISWLIVQASSPTVVANCKLALIYDWLFYDKQYDCIMDIEPAILAIMHNLNSDSDISVTLVDFLVKTANLYFPLVKDQVIGCIRYGLNDAFRVSVF 444

The following BLAST results are available for this feature:

BLAST of Integrator complex subunit 3 vs. Ensembl Human
BLAST of Integrator complex subunit 3 vs. Ensembl Celegans
BLAST of Integrator complex subunit 3 vs. Ensembl Fly
BLAST of Integrator complex subunit 3 vs. Ensembl Zebrafish
BLAST of Integrator complex subunit 3 vs. Ensembl Xenopus
BLAST of Integrator complex subunit 3 vs. Ensembl Mouse
BLAST of Integrator complex subunit 3 vs. UniProt/SwissProt
BLAST of Integrator complex subunit 3 vs. TrEMBL
BLAST of Integrator complex subunit 3 vs. Ensembl Cavefish
BLAST of Integrator complex subunit 3 vs. Ensembl Sea Lamprey
BLAST of Integrator complex subunit 3 vs. Ensembl Yeast
BLAST of Integrator complex subunit 3 vs. Ensembl Nematostella
BLAST of Integrator complex subunit 3 vs. Ensembl Medaka
BLAST of Integrator complex subunit 3 vs. Planmine SMEST

BLAST of Integrator complex subunit 3 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
INTS3	8.326e-67	34.09	integrator complex subunit 3 [Source:HGNC Symbol;A...	[more]
INTS3	8.326e-67	34.09	integrator complex subunit 3 [Source:HGNC Symbol;A...	[more]
INTS3	8.326e-67	34.09	integrator complex subunit 3 [Source:HGNC Symbol;A...	[more]
INTS3	8.326e-67	34.09	integrator complex subunit 3 [Source:HGNC Symbol;A...	[more]
INTS3	1.256e-47	34.90	integrator complex subunit 3 [Source:HGNC Symbol;A...	[more]

BLAST of Integrator complex subunit 3 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 4


Match Name	E-value	Identity	Description
Y92H12A.4	1.866e-18	24.09	pep chromosome:WBcel235:I:1520239:1539206:1 gene:W...	[more]
Y92H12A.4	3.984e-18	24.09	pep chromosome:WBcel235:I:1517542:1539206:1 gene:W...	[more]
Y92H12A.4	6.271e-18	24.09	pep chromosome:WBcel235:I:1514755:1539496:1 gene:W...	[more]
Y92H12A.4	6.271e-18	24.09	pep chromosome:WBcel235:I:1514755:1540847:1 gene:W...	[more]

BLAST of Integrator complex subunit 3 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1


Match Name	E-value	Identity	Description
IntS3	1.713e-58	30.89	gene:FBgn0262117 transcript:FBtr0111268	[more]

BLAST of Integrator complex subunit 3 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ints3	1.356e-67	33.57	integrator complex subunit 3 [Source:NCBI gene;Acc...	[more]

BLAST of Integrator complex subunit 3 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Integrator complex subunit 3 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3


Match Name	E-value	Identity	Description
Ints3	1.142e-67	32.72	integrator complex subunit 3 [Source:MGI Symbol;Ac...	[more]
Ints3	1.142e-67	32.72	integrator complex subunit 3 [Source:MGI Symbol;Ac...	[more]
Ints3	1.168e-67	32.72	integrator complex subunit 3 [Source:MGI Symbol;Ac...	[more]

BLAST of Integrator complex subunit 3 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q7TPD0\|INT3_MOUSE	7.991e-67	32.72	Integrator complex subunit 3 OS=Mus musculus OX=10...	[more]
sp\|Q1LXC9\|INT3_DANRE	1.024e-66	33.57	Integrator complex subunit 3 OS=Danio rerio OX=795...	[more]
sp\|Q5RE70\|INT3_PONAB	2.185e-66	34.09	Integrator complex subunit 3 OS=Pongo abelii OX=96...	[more]
sp\|Q68E01\|INT3_HUMAN	1.313e-64	34.00	Integrator complex subunit 3 OS=Homo sapiens OX=96...	[more]
sp\|Q7PRB8\|INT3_ANOGA	2.210e-63	33.17	Integrator complex subunit 3 homolog OS=Anopheles ...	[more]

BLAST of Integrator complex subunit 3 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A2P1E6J6	0.000e+0	99.61	Integrator complex subunit 3-like protein (Fragmen...	[more]
A0A4Y2F9G1	3.798e-123	29.78	Integrator complex subunit 3 OS=Araneus ventricosu...	[more]
A0A2D0S6G0	2.188e-121	29.92	integrator complex subunit 3 isoform X3 OS=Ictalur...	[more]
W5UL55	3.877e-121	30.12	Integrator complex subunit 3 OS=Ictalurus punctatu...	[more]
A0A2D0S509	5.801e-120	29.84	integrator complex subunit 3 isoform X1 OS=Ictalur...	[more]

BLAST of Integrator complex subunit 3 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ints3	3.930e-122	30.12	integrator complex subunit 3 [Source:NCBI gene;Acc...	[more]

BLAST of Integrator complex subunit 3 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ENSPMAT00000009493.1	2.920e-63	33.08	pep scaffold:Pmarinus_7.0:GL478527:1630:39614:1 ge...	[more]

BLAST of Integrator complex subunit 3 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Integrator complex subunit 3 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO31965	1.481e-67	33.83	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Integrator complex subunit 3 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ints3	3.210e-70	34.79	integrator complex subunit 3 [Source:NCBI gene;Acc...	[more]

BLAST of Integrator complex subunit 3 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2


Match Name	E-value	Identity	Description
SMESG000033343.1	0.000e+0	99.74	SMESG000033343.1	[more]
SMESG000033340.1	0.000e+0	93.02	SMESG000033340.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30020591 ID=SMED30020591|Name=Integrator complex subunit 3|organism=Schmidtea mediterranea sexual|type=transcript|length=3543bp
CAAAATTAGTATATTATATAAAAATATTGTTATTTTTAAAAACAATTTCA
ATTTTGATATTAAATGGAAAATAATTACCGACTTGGTATTATTTTTAATA
GTATAGACGCATACCCTAAAAATTTATCAATTATTGATGAGTCAGGGGAA
TATGTTCGTAGCCTTAAAGAAGACAAAGCTCTTATTATTAATCGAGGTCA
ATCGGAAGAAGATAATATGCGAATTCAATTAGGAATTCTATATTTTTTAC
TCACTGAACGTTCACAAACACAGTTTGATTTTAAAGATTTAATTTTAATA
AGTCGAGATGGTGTAAAAGCTTGTTCTGGTCACTTGATTACCTTAATTTC
CGAAAATTGGAATCGATTAAATACTGACGTGAGGACAAATGTACTCAGTA
TATTGATTGATTTTATATCTTTTCCCATGGCTGATTCATTGTTTATGGCA
ATATTTAAACGGATGATTACTGGTGATCTGAGTCAATCGAATTTGTGGTT
AATTGAAAATATGCTAAATCTCATTGAAGAGCACAAAGAATTGCTAGTGA
AAGATAAGAAGTTGTTACCGATGATTGTATATACTTATTTGCGCTTGATT
CCCACCCATTATCAATTCAGCATCGCAATGAATACTCCGAATAACAATCT
AGCTCGGCTTTGTAGAAAAGAAATCGCGCTTGTAATGGATGTAATCAGGA
ATAATTTTGACGAATGCTGTAAGCAAGTTGGGAGAGATTTGCTATTTACT
CTCACACAAGTTTCCAACATTCCTGAATTCAATAAATTATGGTCAGAAAT
GAACTCGAGTTTAGAAAAACTATCAAATCAATATACTAATATCGGTGAAG
TATTCAGTATGGGTACAAATAAAATTGTCATTGCCACTGCCATTCCATTT
GATATGGAGAATTGGATCCTCTGGACTATGAGAAATGTCCATCATTGTTC
CACAAATCCATACAAAAGATATCAAGACCTTTTTAACAAACGATTTTTTT
CTACTGTCGAAAGTCAAAACCTACGTCCCTTTTTGATTCGCTACATCATT
AGAGCTTTTTATCCTGACAATGAAATGATCGGTTCCACCTTAATATCCAG
ATGGGCAACAATTTCATGGTTAATTGTCCAAGCATCTTCTCCTACAGTTG
TGGCAAATTGTAAACTTGCCCTCATATATGATTGGCTGTTCTACGACAAA
CAATATGACTGTATCATGGACATCGAACCGGCAATTCTTGCAATTATGCA
CAATTTAACAAAATATTCCCATGTTTCTATCACTTTGGTCGACTTCTTAG
TTAAAACAGCCAATCTTTATTTTCCACTTGTAAAAGACCAAATTATCAGT
TGCTGTCGTTTTGGCTTAAACGATGCATTCAGAGTTAGTGTATTCAGATC
ACTTGCTCCACTTCACGAGGTCTTGAGACATCACATAGAACTTTATAAGC
AGTTTCTCGAATTAATAGGTGATACGTCCAATGTTTATCCACAGATACCA
CTGAATAATGTCCCTATTCCTAAACCTGTAGAAAACGTAATTGCAACTGT
AAATCCAGTCAATAATCCCGTCGCTCCTGCTCCTGAAGTTGTTGTGCAAA
GAGAAAGAAATGGAACCCCTAAAACACTGTCTCCTGTAAATAAAGAAAAA
CCAGTGGAGCATATTAACAAAATTGTTGTCACAAGCAAAATAAATAATGC
CCCGAAATCGGCATTATTCGATAATAAACCAGTAGTGGATTTGACAATAT
CAGATACTGAACCTACTCAAACAGAAGATATTTCATTCGATGATCTTAAG
CGTCGATTTATGAAATATTCTTTGACTTTTGACTACAATGTTGAACGAAT
AGATATTCCATCAACAATTTGTCAGATTAATTCTTCAGTAGCGCCAGATC
TTGAACGGTTATATGAAACAGCGGAAAATTGTCGTTCTCTCATTGTCAAA
AATAAGGGCAAACGTGATAATAAAAAGTCAGTAAAACGTGGACAAAAAAG
ACTGGACACAATTGATGATAGTGAATTATCTGGAGACGAAGAAAACCTTC
AACATCTCTATGAAAAAATGGAAAAAGTTGTCATTGCGATTTTGAATGAT
GACAATTTTGATGATCTCGGTATCGCGGGAAAAACCGCTGCTGTAATTTG
TGAAATCTGCTATCCATTTTTCGATCGAAAACTTTTCCCAGAAGATCCCG
ACGAAGAAAAACTTAAAGCCTCCCTTTCGTCACCAGTTTTCGTTTTATTC
CGAAATATATGCTCGATGAGTACTCAAGATAATAAACGGGAACTTCTTTT
GCTTCTTCTTTCTGAAATGCAAATGCGACAACCAAGAGTCGGATATTATC
TTTTATATTATCTCAAAGTCGCATACGCTACCGATCCAGATTTATCGACT
TATCGGAGTCTTTGTAATAGCTTGGAAAAACCAAATTTGAAAAATTCTCT
TTTCAAAGATCTAGAGCTATTAAGCAATGATGACTCAAAATTAATGGTTT
ATCTACTCCCTGGTCTCTATACCGCGTTTTCAACAGAAATGGTAGGTAGC
CCAAAATTTGCCCATTTAATAATTTCCTCACTCGACGCCGCGGAAATTAA
TGAACTCGGCCTTCAAATTCAGAAGAAAAATCTCGTGATGTTTGATTCAA
ATTCAGTTGTGGAAATATTAAAAGACAGTTTGGATTGGGGAACTATCGAA
CAATATTTTCTTTGGGAATTGCTACTAGCTCACAATATTTCTTCTAAACA
CTTTTACGGCTTAATTCCATATTTAGATTTTAAAAAACACCCTGAAGCCA
TTTTACGATTTTCTAATTTCCTTCGACAAGAGAAACCAAATTATGAATTA
ATTAAATTATTACTAAATCGTGAAGTGGAACGTGGGGATCAGTTTACATC
AACGTTGTTGCATTTTTGGAGTTCAGAAAGTAACTCCACGACGTCTAAAT
TCGTTAGTATCCTTCACACTATTATATCAGCATCATTAGGCAACAATATG
AAAGACAAGAAAAAAAATAGACATTCTCAATTCGCTGAGGAAGGCGGAGT
TGACCTAATCAAAATTTTGGGTCATTTAGATTTCATGAGACTGAATTGCA
AAAATATATCATTTCTTCAAGAAGAATCCATTCAATCAGATCTCCAGCAG
GTTTTGAATTCGAAATCGATGCTCGATGATATCAAATCTCGATTTTCTGA
GCTTTTGGCATTTGTCGAAGAAGAAGATGAAGATTTCTCAGATGATGAAA
ATGTAAACGAGAAAAATACATCGACTGGACGGGTGCTGCGAAACCTGGAT
TCTCGTCGATACCCATCGGATAAAAAGACTTTCGAAGAGTCTAATTATCA
TAAAAGCACAACTAAACGACATCTTTTCAATAGTCCTGATTCCTCAAGCT
CTGAAGACGAGTCAGATACAGATGTCAATACTCGAAAAACACATTATCCA
TGTCGCTCAAAAAGACGTTTGATGATAGCAGATTAAATGTTTGATATGTA
GTTCGTATAGAAATTTGTTATGTAATATAATGTTGTATTTAAA

protein sequence of SMED30020591-orf-1

>SMED30020591-orf-1 ID=SMED30020591-orf-1|Name=SMED30020591-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1141bp
MENNYRLGIIFNSIDAYPKNLSIIDESGEYVRSLKEDKALIINRGQSEED
NMRIQLGILYFLLTERSQTQFDFKDLILISRDGVKACSGHLITLISENWN
RLNTDVRTNVLSILIDFISFPMADSLFMAIFKRMITGDLSQSNLWLIENM
LNLIEEHKELLVKDKKLLPMIVYTYLRLIPTHYQFSIAMNTPNNNLARLC
RKEIALVMDVIRNNFDECCKQVGRDLLFTLTQVSNIPEFNKLWSEMNSSL
EKLSNQYTNIGEVFSMGTNKIVIATAIPFDMENWILWTMRNVHHCSTNPY
KRYQDLFNKRFFSTVESQNLRPFLIRYIIRAFYPDNEMIGSTLISRWATI
SWLIVQASSPTVVANCKLALIYDWLFYDKQYDCIMDIEPAILAIMHNLTK
YSHVSITLVDFLVKTANLYFPLVKDQIISCCRFGLNDAFRVSVFRSLAPL
HEVLRHHIELYKQFLELIGDTSNVYPQIPLNNVPIPKPVENVIATVNPVN
NPVAPAPEVVVQRERNGTPKTLSPVNKEKPVEHINKIVVTSKINNAPKSA
LFDNKPVVDLTISDTEPTQTEDISFDDLKRRFMKYSLTFDYNVERIDIPS
TICQINSSVAPDLERLYETAENCRSLIVKNKGKRDNKKSVKRGQKRLDTI
DDSELSGDEENLQHLYEKMEKVVIAILNDDNFDDLGIAGKTAAVICEICY
PFFDRKLFPEDPDEEKLKASLSSPVFVLFRNICSMSTQDNKRELLLLLLS
EMQMRQPRVGYYLLYYLKVAYATDPDLSTYRSLCNSLEKPNLKNSLFKDL
ELLSNDDSKLMVYLLPGLYTAFSTEMVGSPKFAHLIISSLDAAEINELGL
QIQKKNLVMFDSNSVVEILKDSLDWGTIEQYFLWELLLAHNISSKHFYGL
IPYLDFKKHPEAILRFSNFLRQEKPNYELIKLLLNREVERGDQFTSTLLH
FWSSESNSTTSKFVSILHTIISASLGNNMKDKKKNRHSQFAEEGGVDLIK
ILGHLDFMRLNCKNISFLQEESIQSDLQQVLNSKSMLDDIKSRFSELLAF
VEEEDEDFSDDENVNEKNTSTGRVLRNLDSRRYPSDKKTFEESNYHKSTT
KRHLFNSPDSSSSEDESDTDVNTRKTHYPCRSKRRLMIAD*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **cellular component**
Term	Definition
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0070876	SOSS complex
GO:0005794	Golgi apparatus

Vocabulary: **biological process**
Term	Definition
GO:0006281	DNA repair
GO:0006974	cellular response to DNA damage stimulus
GO:0007093	mitotic cell cycle checkpoint
GO:0010212	response to ionizing radiation

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000101	muscle cell
PLANA:0002109	X1 cell
PLANA:0003001	lateral region of the whole animal

Vocabulary: **INTERPRO**
Term	Definition
IPR019333	Int_cplx_su3

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR019333	Integrator complex subunit 3	PFAM	PF10189	Ints3	coord: 242..453 e-value: 1.9E-56 score: 190.9
IPR019333	Integrator complex subunit 3	PANTHER	PTHR13587	FAMILY NOT NAMED	coord: 49..993
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1082..1130
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1082..1103

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Integrator complex subunit 3

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 1

Owlery

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