Ribonuclease t2

Overview


Name	Ribonuclease t2
Smed ID	SMED30020534
Length (bp)	994

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Ribonuclease t2 (SMED30020534) t-SNE clustered cells

Violin plots show distribution of expression levels for Ribonuclease t2 (SMED30020534) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Ribonuclease t2 (SMED30020534) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Ribonuclease t2 (SMED30020534) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30020534

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 21

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
intestinal phagocyte	SMED30020534	SMESG000048912.1	Contig5956	newmark_ests	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30020534	SMESG000048912.1	Contig5956	uc_Smed_v2	PMID:23079596 Forsthoefel et al., 2012
protonephridia	SMED30020534	SMESG000048912.1 SMESG000020005.1	dd_Smed_v4_172_1_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30020534	SMESG000048912.1 SMESG000020005.1	dd_Smed_v4_172_1_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30020534	SMESG000048912.1 SMESG000020005.1	dd_Smed_v4_172_1_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020534	SMESG000048912.1	Contig4782	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020534	SMESG000048912.1	Contig4782	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020534	SMESG000048912.1 SMESG000048911.1	Contig38009	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020534	SMESG000048912.1 SMESG000048911.1	Contig38009	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020534	SMESG000048912.1	Contig32693	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020534	SMESG000048912.1	Contig26842	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020534	SMESG000048912.1	Contig26842	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020534	SMESG000048912.1	Contig5956	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020534	SMESG000048912.1	Contig5956	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020534	SMESG000048912.1 SMESG000048911.1	Contig15514	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020534	SMESG000048912.1 SMESG000048911.1	Contig15514	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020534	SMESG000048912.1	Contig22833	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020534	SMESG000048912.1	Contig22833	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020534	SMESG000021154.1	Contig4782	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020534	SMESG000021154.1	Contig4782	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30020534	SMESG000048912.1 SMESG000020005.1	dd_Smed_v6_172_1	dd_Smed_v6	PMID:29674432 Plass et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of Ribonuclease t2 vs. Ensembl Human
Match: RNASET2 (ribonuclease T2 [Source:HGNC Symbol;Acc:HGNC:21686])

HSP 1 Score: 97.4413 bits (241), Expect = 4.091e-23
Identity = 55/165 (33.33%), Postives = 95/165 (57.58%), Query Frame = 3

Query:  144 DWDYLVMAVEWPPSFCYTFPKKIQ--CCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEW----NPLGNCSKDFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQC 620
            +W  L+M   WP + C    +KIQ  C D      W +HGLWP  S+G     C  +  ++ +++K ++ ++   W    +   N S+ FWKHEW+ HGTCA+    L+++ +YF  ++++ + +DL ++L +  +KP  N  Y+V+DF + + +VY V PK+QC
Sbjct:   33 EWKKLIMVQHWPETVC----EKIQNDCRDPPDY--WTIHGLWPDKSEG-----CNRSWPFNLEEIKDLLPEMRAYWPDVIHSFPNRSR-FWKHEWEKHGTCAAQVDALNSQKKYFGRSLELYRELDLNSVLLKLGIKPSIN-YYQVADFKDALARVYGVIPKIQC 184

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BLAST of Ribonuclease t2 vs. Ensembl Human
Match: RNASET2 (ribonuclease T2 [Source:HGNC Symbol;Acc:HGNC:21686])

HSP 1 Score: 97.4413 bits (241), Expect = 4.383e-23
Identity = 55/165 (33.33%), Postives = 95/165 (57.58%), Query Frame = 3

Query:  144 DWDYLVMAVEWPPSFCYTFPKKIQ--CCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEW----NPLGNCSKDFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQC 620
            +W  L+M   WP + C    +KIQ  C D      W +HGLWP  S+G     C  +  ++ +++K ++ ++   W    +   N S+ FWKHEW+ HGTCA+    L+++ +YF  ++++ + +DL ++L +  +KP  N  Y+V+DF + + +VY V PK+QC
Sbjct:   33 EWKKLIMVQHWPETVC----EKIQNDCRDPPDY--WTIHGLWPDKSEG-----CNRSWPFNLEEIKDLLPEMRAYWPDVIHSFPNRSR-FWKHEWEKHGTCAAQVDALNSQKKYFGRSLELYRELDLNSVLLKLGIKPSIN-YYQVADFKDALARVYGVIPKIQC 184

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Query:  144 DWDYLVMAVEWPPSFCYTFPKKIQ--CCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEW----NPLGNCSKDFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQC 620
            +W  L+M   WP + C    +KIQ  C D      W +HGLWP  S+G     C  +  ++ +++K ++ ++   W    +   N S+ FWKHEW+ HGTCA+    L+++ +YF  ++++ + +DL ++L +  +KP  N  Y+V+DF + + +VY V PK+QC
Sbjct:   33 EWKKLIMVQHWPETVC----EKIQNDCRDPPDY--WTIHGLWPDKSEG-----CNRSWPFNLEEIKDLLPEMRAYWPDVIHSFPNRSR-FWKHEWEKHGTCAAQVDALNSQKKYFGRSLELYRELDLNSVLLKLGIKPSIN-YYQVADFKDALARVYGVIPKIQC 184

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BLAST of Ribonuclease t2 vs. Ensembl Human
Match: RNASET2 (ribonuclease T2 [Source:HGNC Symbol;Acc:HGNC:21686])

HSP 1 Score: 91.6633 bits (226), Expect = 2.733e-21
Identity = 53/159 (33.33%), Postives = 91/159 (57.23%), Query Frame = 3

Query:  162 MAVEWPPSFCYTFPKKIQ--CCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEW----NPLGNCSKDFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQC 620
            M   WP + C    +KIQ  C D      W +HGLWP  S+G     C  +  ++ +++K ++ ++   W    +   N S+ FWKHEW+ HGTCA+    L+++ +YF  ++++ + +DL ++L +  +KP  N  Y+V+DF + + +VY V PK+QC
Sbjct:    1 MVQHWPETVC----EKIQNDCRDPPDY--WTIHGLWPDKSEG-----CNRSWPFNLEEIKDLLPEMRAYWPDVIHSFPNRSR-FWKHEWEKHGTCAAQVDALNSQKKYFGRSLELYRELDLNSVLLKLGIKPSIN-YYQVADFKDALARVYGVIPKIQC 146

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BLAST of Ribonuclease t2 vs. Ensembl Human
Match: AL159163.1 (novel protein)

HSP 1 Score: 81.6481 bits (200), Expect = 7.475e-18
Identity = 52/181 (28.73%), Postives = 93/181 (51.38%), Query Frame = 3

Query:  144 DWDYLVMAVEWPPSFCYTFPKKIQ--CCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEW----NPLGNCSKDFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCTHYKGKIYILAMEFCF 668
            +W  L+M   WP + C    +KIQ  C D      W +HGLWP  S+G     C  +  ++ +++K ++ ++   W    +   N S+ FWKHEW+ HGTCA+    L+++ +YF  ++++ + +DL ++L +  +KP  N      + +N+      VEP  + T  +  I++L     F
Sbjct:   14 EWKKLIMVQHWPETVC----EKIQNDCRDPPDY--WTIHGLWPDKSEG-----CNRSWPFNLEEIKDLLPEMRAYWPDVIHSFPNRSR-FWKHEWEKHGTCAAQVDALNSQKKYFGRSLELYRELDLNSVLLKLGIKPSINYYQTTEEDLNL-----DVEPTTEDTAEEVTIHVLLHSALF 177

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BLAST of Ribonuclease t2 vs. Ensembl Celegans
Match: rnst-2 (pep chromosome:WBcel235:V:1061595:1067908:1 gene:WBGene00019624.1 transcript:K10C9.3.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:rnst-2)

HSP 1 Score: 97.4413 bits (241), Expect = 2.514e-23
Identity = 72/233 (30.90%), Postives = 106/233 (45.49%), Query Frame = 3

Query:  141 EDWDYLVMAVEWPPSFCYTFPKKI--QCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASA-YDEKKLKPIMEDLLKEWNPL--GNCSKDFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEP-KLQCTH-YKGKIYILA-MEFCFDTKLNIIMCPKRHKSEDHLSR-HRNKCRKPRNSTNPIHIPCTTGFLYQP 812
            E +DYL+    +P + C      +   C   S    W++HGLWP+   GS P  C+     +DE  +K I + L+  W  L      + FWKHE+  HGTCA   KL  +EL YF E +++   +D+   L   +V P + K    SD  N +  V   +  +  C    K K ++L  +  C +  L I  CP   K  + +SR  R+  R  R    P   PC   F+Y P
Sbjct:   21 EPFDYLMFTTIYPTAVCRADDDSVPESCEIPSGTPQWSIHGLWPNFENGSYPQNCRGTPRHFDENLIKSIEDRLVVVWPNLYPKKTIQSFWKHEYDKHGTCAQSEKLFESELAYFTEVMKVFDSIDVAGGL--KSVGP-SEKPITSSDLKNALSGVTSGKTFQFHCLRDKKTKQFLLGDIRLCLNKDLTIRDCPTDGKHPNRVSRFERSIGRNRRGPPLPSFQPCPAEFIYLP 250

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BLAST of Ribonuclease t2 vs. Ensembl Fly
Match: RNaseX25 (gene:FBgn0010406 transcript:FBtr0076752)

HSP 1 Score: 101.293 bits (251), Expect = 3.235e-24
Identity = 60/196 (30.61%), Postives = 95/196 (48.47%), Query Frame = 3

Query:  132 MKDEDWDYLVMAVEWPPSFCYTFPKK---IQCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPLGNCSKD--FWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCTHYKGK---IYILAMEFCFDTKLNIIMC 695
            ++D +WD L+   +WP + CY + ++    +C        W +HG+WP+      P  C N++ +D  KL PI + L   W  L         WKHEW+ HGTCA   + L  EL+YF + +  ++   ++ IL  +++ PD+N    V+   N I K     P + C  Y GK    Y+  +  CF   L +I C
Sbjct:   71 VQDHNWDVLIFTQQWPVTTCYHWREENPDQECSLPQKKEFWTIHGIWPTKLHQMGPNFCNNSANFDPSKLNPIEDRLETFWPDLKGMDSTEWLWKHEWQKHGTCAMLVEELDNELKYFEQGLTWREEYIMSRILDASDIHPDSNN--TVAAINNAIVKALGKNPSIHCL-YDGKHGISYLSEIRICFSKSLELIDC 263

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BLAST of Ribonuclease t2 vs. Ensembl Zebrafish
Match: rnaset2 (ribonuclease T2 [Source:NCBI gene;Acc:791890])

HSP 1 Score: 102.449 bits (254), Expect = 2.994e-25
Identity = 62/196 (31.63%), Postives = 105/196 (53.57%), Query Frame = 3

Query:  144 DWDYLVMAVEWPPSFCYTFPKKIQCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEW-NPLGNCSKDFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCTH--YKGKIYILA-MEFCFDTKLNIIMCPKRHKSED 719
            +W  L++   WP +FC     K++ C T   + W LHGLWP++      + C  +  ++   ++ I+ ++ K W + L   S  FW +EW  HGTCA+ ++ L++E +YF + +++    DL ++L +N + P + K Y + D    I   Y V+PK+QC H    G++ IL  +E C D    ++ C K   SED
Sbjct:   26 EWTKLILTQHWPQTFC-----KMEHCKTD-FSYWTLHGLWPNTG-----VRCNTSWHFNASLIEDILPEMEKFWPDLLEPSSPKFWNYEWTKHGTCAAKSESLNSEHKYFGKALELYHKFDLNSVLLKNQIVP-SEKHYTLEDVEEAITSAYGVKPKIQCVHPGQGGQVQILGQIEICVDRDFQLMGCEK--SSED 207

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Query:  144 DWDYLVMAVEWPPSFCYTFPKKIQCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEW-NPLGNCSKDFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCTH--YKGKIYILA-MEFCFDTKLNIIMCPKRHKSED 719
            +W  L++   WP +FC     K++ C T   + W LHGLWP++      + C  +  ++   ++ I+ ++ K W + L   S  FW +EW  HGTCA+ ++ L++E +YF + +++    DL ++L +N + P + K Y + D    I   Y V+PK+QC H    G++ IL  +E C D    ++ C K   SED
Sbjct:   26 EWTKLILTQHWPQTFC-----KMEHCKTD-FSYWTLHGLWPNTG-----VRCNTSWHFNASLIEDILPEMEKFWPDLLEPSSPKFWNYEWTKHGTCAAKSESLNSEHKYFGKALELYHKFDLNSVLLKNQIVP-SEKHYTLEDVEEAITSAYGVKPKIQCVHPGQGGQVQILGQIEICVDRDFQLMGCEK--SSED 207

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Query:  144 DWDYLVMAVEWPPSFCYTFPKKIQCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEW-NPLGNCSKDFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCTH--YKGKIYILA-MEFCFDTKLNIIMCPKRHKSED 719
            +W  L++   WP +FC     K++ C T   + W LHGLWP++      + C  +  ++   ++ I+ ++ K W + L   S  FW +EW  HGTCA+ ++ L++E +YF + +++    DL ++L +N + P + K Y + D    I   Y V+PK+QC H    G++ IL  +E C D    ++ C K   SED
Sbjct:   26 EWTKLILTQHWPQTFC-----KMEHCKTD-FSYWTLHGLWPNTG-----VRCNTSWHFNASLIEDILPEMEKFWPDLLEPSSPKFWNYEWTKHGTCAAKSESLNSEHKYFGKALELYHKFDLNSVLLKNQIVP-SEKHYTLEDVEEAITSAYGVKPKIQCVHPGQGGQVQILGQIEICVDRDFQLMGCEK--SSED 207

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Query:  144 DWDYLVMAVEWPPSFCYTFPKKIQCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEW-NPLGNCSKDFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCTH--YKGKIYILA-MEFCFDTKLNIIMCPKRHKSED 719
            +W  L++   WP +FC     K++ C T   + W LHGLWP++      + C  +  ++   ++ I+ ++ K W + L   S  FW +EW  HGTCA+ ++ L++E +YF + +++    DL ++L +N + P + K Y + D    I   Y V+PK+QC H    G++ IL  +E C D    ++ C K   SED
Sbjct:   26 EWTKLILTQHWPQTFC-----KMEHCKTD-FSYWTLHGLWPNTG-----VRCNTSWHFNASLIEDILPEMEKFWPDLLEPSSPKFWNYEWTKHGTCAAKSESLNSEHKYFGKALELYHKFDLNSVLLKNQIVP-SEKHYTLEDVEEAITSAYGVKPKIQCVHPGQGGQVQILGQIEICVDRDFQLMGCEK--SSED 207

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Query:  144 DWDYLVMAVEWPPSFCYTFPKKIQCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEW-NPLGNCSKDFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCTH--YKGKIYILA-MEFCFDTKLNIIMCPKRHKSED 719
            +W  L++   WP +FC     K++ C T   + W LHGLWP++      + C  +  ++   ++ I+ ++ K W + L   S  FW +EW  HGTCA+ ++ L++E +YF + +++    DL ++L +N + P + K Y + D    I   Y V+PK+QC H    G++ IL  +E C D    ++ C K   SED
Sbjct:   26 EWTKLILTQHWPQTFC-----KMEHCKTD-FSYWTLHGLWPNTG-----VRCNTSWHFNASLIEDILPEMEKFWPDLLEPSSPKFWNYEWTKHGTCAAKSESLNSEHKYFGKALELYHKFDLNSVLLKNQIVP-SEKHYTLEDVEEAITSAYGVKPKIQCVHPGQGGQVQILGQIEICVDRDFQLMGCEK--SSED 207

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BLAST of Ribonuclease t2 vs. Ensembl Xenopus
Match: rnaset2 (ribonuclease T2 [Source:NCBI gene;Acc:780173])

HSP 1 Score: 67.0106 bits (162), Expect = 2.260e-12
Identity = 41/134 (30.60%), Postives = 75/134 (55.97%), Query Frame = 3

Query:  192 YTFPKKIQCCDTSHVTG----WNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPLGNCSKD-FWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVN 578
            + FP   Q  D SH       W LHGLWP  ++      C N+  ++  +++ I+ +L   W  + + +K   WKHEW+ HGTCA+  + L+T+ +YF++ +++   VDL ++L ++ + P + K Y+V  ++ 
Sbjct:   40 FVFPLASQM-DHSHCKNPPKYWTLHGLWPDKAQ-----MCNNSWPFEYSEIQDILPELNHYWPDILHPNKSQLWKHEWQKHGTCAASLECLNTQHKYFSKGLELYTKVDLNSVLEKSGIVP-STKYYQVRCYLG 166

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BLAST of Ribonuclease t2 vs. Ensembl Mouse
Match: Rnaset2a (ribonuclease T2A [Source:MGI Symbol;Acc:MGI:1915445])

HSP 1 Score: 102.449 bits (254), Expect = 6.212e-25
Identity = 64/235 (27.23%), Postives = 120/235 (51.06%), Query Frame = 3

Query:  129 WMKDEDWDYLVMAVEWPPSFCYTFPKKIQCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPLGNCSKD---FWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCT---HYKGKIYILAMEFCFDTK-LNIIMCPKRHKSEDHLSRHRNKCRKPRNSTNPIHIPCTTGFLYQP 812
            W    +W  L++   WPP+ C    K++  C  S +  W +HGLWP  ++      C  +  ++  ++K ++ D+   W  + + S +   FWKHEW  HGTCA+    L++E +YF +++ + K +DL ++L +  +KP  N  Y+++DF + + ++Y V PK+QC      +    +  +E CF  + L++  C    +  + LS  +        ST+ + + C  G ++ P
Sbjct:   33 WSGSHEWKKLILTQHWPPTVC----KEVNSCQDS-LDYWTIHGLWPDRAED-----CNQSWHFNLDEIKDLLRDMKIYWPDVIHRSSNRSQFWKHEWVKHGTCAAQVDALNSEKKYFGKSLDLYKQIDLNSVLQKFGIKPSIN-YYQLADFKDALTRIYGVVPKIQCLMPEQGESVQTVGQIELCFTKEDLHLRNCT---EPGEQLSSRQEAWLAMEASTHGMMV-CEDGPIFYP 252

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Query:  129 WMKDEDWDYLVMAVEWPPSFCYTFPKKIQCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPLGNCSKD---FWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCT---HYKGKIYILAMEFCFDTK-LNIIMCPKRHKSEDHLSRHRNKCRKPRNSTNPIHIPCTTGFLYQP 812
            W    +W  L++   WPP+ C    K++  C  S +  W +HGLWP  ++      C  +  ++  ++K ++ D+   W  + + S +   FWKHEW  HGTCA+    L++E +YF +++ + K +DL ++L +  +KP  N  Y+++DF + + ++Y V PK+QC      +    +  +E CF  + L++  C    +  + LS  +        ST+ + + C  G ++ P
Sbjct:   33 WSGSHEWKKLILTQHWPPTVC----KEVNSCQDS-LDYWTIHGLWPDRAED-----CNQSWHFNLDEIKDLLRDMKIYWPDVIHRSSNRSQFWKHEWVKHGTCAAQVDALNSEKKYFGKSLDLYKQIDLNSVLQKFGIKPSIN-YYQLADFKDALTRIYGVVPKIQCLMPEQGESVQTVGQIELCFTKEDLHLRNCT---EPGEQLSSRQEAWLAMEASTHGMMV-CEDGPIFYP 252

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BLAST of Ribonuclease t2 vs. Ensembl Mouse
Match: Gm49673 (predicted gene, 49673 [Source:MGI Symbol;Acc:MGI:6215117])

HSP 1 Score: 102.449 bits (254), Expect = 6.212e-25
Identity = 64/235 (27.23%), Postives = 120/235 (51.06%), Query Frame = 3

Query:  129 WMKDEDWDYLVMAVEWPPSFCYTFPKKIQCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPLGNCSKD---FWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCT---HYKGKIYILAMEFCFDTK-LNIIMCPKRHKSEDHLSRHRNKCRKPRNSTNPIHIPCTTGFLYQP 812
            W    +W  L++   WPP+ C    K++  C  S +  W +HGLWP  ++      C  +  ++  ++K ++ D+   W  + + S +   FWKHEW  HGTCA+    L++E +YF +++ + K +DL ++L +  +KP  N  Y+++DF + + ++Y V PK+QC      +    +  +E CF  + L++  C    +  + LS  +        ST+ + + C  G ++ P
Sbjct:   33 WSGSHEWKKLILTQHWPPTVC----KEVNSCQDS-LDYWTIHGLWPDRAED-----CNQSWHFNLDEIKDLLRDMKIYWPDVIHRSSNRSQFWKHEWVKHGTCAAQVDALNSEKKYFGKSLDLYKQIDLNSVLQKFGIKPSIN-YYQLADFKDALTRIYGVVPKIQCLMPEQGESVQTVGQIELCFTKEDLHLRNCT---EPGEQLSSRQEAWLAMEASTHGMMV-CEDGPIFYP 252

[Close]

BLAST of Ribonuclease t2 vs. Ensembl Mouse
Match: Gm49721 (predicted gene, 49721 [Source:MGI Symbol;Acc:MGI:6215195])

HSP 1 Score: 102.449 bits (254), Expect = 6.212e-25
Identity = 64/235 (27.23%), Postives = 120/235 (51.06%), Query Frame = 3

Query:  129 WMKDEDWDYLVMAVEWPPSFCYTFPKKIQCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPLGNCSKD---FWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCT---HYKGKIYILAMEFCFDTK-LNIIMCPKRHKSEDHLSRHRNKCRKPRNSTNPIHIPCTTGFLYQP 812
            W    +W  L++   WPP+ C    K++  C  S +  W +HGLWP  ++      C  +  ++  ++K ++ D+   W  + + S +   FWKHEW  HGTCA+    L++E +YF +++ + K +DL ++L +  +KP  N  Y+++DF + + ++Y V PK+QC      +    +  +E CF  + L++  C    +  + LS  +        ST+ + + C  G ++ P
Sbjct:   33 WSGSHEWKKLILTQHWPPTVC----KEVNSCQDS-LDYWTIHGLWPDRAED-----CNQSWHFNLDEIKDLLRDMKIYWPDVIHRSSNRSQFWKHEWVKHGTCAAQVDALNSEKKYFGKSLDLYKQIDLNSVLQKFGIKPSIN-YYQLADFKDALTRIYGVVPKIQCLMPEQGESVQTVGQIELCFTKEDLHLRNCT---EPGEQLSSRQEAWLAMEASTHGMMV-CEDGPIFYP 252

[Close]

BLAST of Ribonuclease t2 vs. Ensembl Mouse
Match: Rnaset2b (ribonuclease T2B [Source:MGI Symbol;Acc:MGI:3702087])

HSP 1 Score: 102.449 bits (254), Expect = 6.212e-25
Identity = 64/235 (27.23%), Postives = 120/235 (51.06%), Query Frame = 3

Query:  129 WMKDEDWDYLVMAVEWPPSFCYTFPKKIQCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPLGNCSKD---FWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCT---HYKGKIYILAMEFCFDTK-LNIIMCPKRHKSEDHLSRHRNKCRKPRNSTNPIHIPCTTGFLYQP 812
            W    +W  L++   WPP+ C    K++  C  S +  W +HGLWP  ++      C  +  ++  ++K ++ D+   W  + + S +   FWKHEW  HGTCA+    L++E +YF +++ + K +DL ++L +  +KP  N  Y+++DF + + ++Y V PK+QC      +    +  +E CF  + L++  C    +  + LS  +        ST+ + + C  G ++ P
Sbjct:   33 WSGSHEWKKLILTQHWPPTVC----KEVNSCQDS-LDYWTIHGLWPDRAED-----CNQSWHFNLDEIKDLLRDMKIYWPDVIHRSSNRSQFWKHEWVKHGTCAAQVDALNSEKKYFGKSLDLYKQIDLNSVLQKFGIKPSIN-YYQLADFKDALTRIYGVVPKIQCLMPEQGESVQTVGQIELCFTKEDLHLRNCT---EPGEQLSSRQEAWLAMEASTHGMMV-CEDGPIFYP 252

[Close]

BLAST of Ribonuclease t2 vs. UniProt/SwissProt
Match: sp|B8XY56|RNT2_DANRE (Ribonuclease T2 OS=Danio rerio OX=7955 GN=rnaset2 PE=2 SV=1)

HSP 1 Score: 102.449 bits (254), Expect = 2.260e-24
Identity = 62/196 (31.63%), Postives = 105/196 (53.57%), Query Frame = 3

Query:  144 DWDYLVMAVEWPPSFCYTFPKKIQCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEW-NPLGNCSKDFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCTH--YKGKIYILA-MEFCFDTKLNIIMCPKRHKSED 719
            +W  L++   WP +FC     K++ C T   + W LHGLWP++      + C  +  ++   ++ I+ ++ K W + L   S  FW +EW  HGTCA+ ++ L++E +YF + +++    DL ++L +N + P + K Y + D    I   Y V+PK+QC H    G++ IL  +E C D    ++ C K   SED
Sbjct:   26 EWTKLILTQHWPQTFC-----KMEHCKTD-FSYWTLHGLWPNTG-----VRCNTSWHFNASLIEDILPEMEKFWPDLLEPSSPKFWNYEWTKHGTCAAKSESLNSEHKYFGKALELYHKFDLNSVLLKNQIVP-SEKHYTLEDVEEAITSAYGVKPKIQCVHPGQGGQVQILGQIEICVDRDFQLMGCEK--SSED 207

[Close]

BLAST of Ribonuclease t2 vs. UniProt/SwissProt
Match: sp|C0HKG6|RNT2B_MOUSE (Ribonuclease T2-B OS=Mus musculus OX=10090 GN=Rnaset2b PE=1 SV=1)

HSP 1 Score: 102.449 bits (254), Expect = 4.345e-24
Identity = 64/235 (27.23%), Postives = 120/235 (51.06%), Query Frame = 3

Query:  129 WMKDEDWDYLVMAVEWPPSFCYTFPKKIQCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPLGNCSKD---FWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCT---HYKGKIYILAMEFCFDTK-LNIIMCPKRHKSEDHLSRHRNKCRKPRNSTNPIHIPCTTGFLYQP 812
            W    +W  L++   WPP+ C    K++  C  S +  W +HGLWP  ++      C  +  ++  ++K ++ D+   W  + + S +   FWKHEW  HGTCA+    L++E +YF +++ + K +DL ++L +  +KP  N  Y+++DF + + ++Y V PK+QC      +    +  +E CF  + L++  C    +  + LS  +        ST+ + + C  G ++ P
Sbjct:   33 WSGSHEWKKLILTQHWPPTVC----KEVNSCQDS-LDYWTIHGLWPDRAED-----CNQSWHFNLDEIKDLLRDMKIYWPDVIHRSSNRSQFWKHEWVKHGTCAAQVDALNSEKKYFGKSLDLYKQIDLNSVLQKFGIKPSIN-YYQLADFKDALTRIYGVVPKIQCLMPEQGESVQTVGQIELCFTKEDLHLRNCT---EPGEQLSSRQEAWLAMEASTHGMMV-CEDGPIFYP 252

[Close]

BLAST of Ribonuclease t2 vs. UniProt/SwissProt
Match: sp|C0HKG5|RNT2A_MOUSE (Ribonuclease T2-A OS=Mus musculus OX=10090 GN=Rnaset2a PE=1 SV=1)

HSP 1 Score: 102.449 bits (254), Expect = 4.345e-24
Identity = 64/235 (27.23%), Postives = 120/235 (51.06%), Query Frame = 3

Query:  129 WMKDEDWDYLVMAVEWPPSFCYTFPKKIQCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPLGNCSKD---FWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCT---HYKGKIYILAMEFCFDTK-LNIIMCPKRHKSEDHLSRHRNKCRKPRNSTNPIHIPCTTGFLYQP 812
            W    +W  L++   WPP+ C    K++  C  S +  W +HGLWP  ++      C  +  ++  ++K ++ D+   W  + + S +   FWKHEW  HGTCA+    L++E +YF +++ + K +DL ++L +  +KP  N  Y+++DF + + ++Y V PK+QC      +    +  +E CF  + L++  C    +  + LS  +        ST+ + + C  G ++ P
Sbjct:   33 WSGSHEWKKLILTQHWPPTVC----KEVNSCQDS-LDYWTIHGLWPDRAED-----CNQSWHFNLDEIKDLLRDMKIYWPDVIHRSSNRSQFWKHEWVKHGTCAAQVDALNSEKKYFGKSLDLYKQIDLNSVLQKFGIKPSIN-YYQLADFKDALTRIYGVVPKIQCLMPEQGESVQTVGQIELCFTKEDLHLRNCT---EPGEQLSSRQEAWLAMEASTHGMMV-CEDGPIFYP 252

[Close]

BLAST of Ribonuclease t2 vs. UniProt/SwissProt
Match: sp|Q7M456|RNOY_CRAGI (Ribonuclease Oy OS=Crassostrea gigas OX=29159 PE=1 SV=1)

HSP 1 Score: 100.908 bits (250), Expect = 4.470e-24
Identity = 57/202 (28.22%), Postives = 95/202 (47.03%), Query Frame = 3

Query:  144 DWDYLVMAVEWPPSFCYTFPKKIQCCDTSHVTGWNLHGLWPSS-SKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPLGNCSK--DFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCTHYKGKI---YILAMEFCFDTKLNIIMCPKRHKSEDHLSR 731
            DW+Y   A +WP + C    +   C     V GW +HGLWPSS ++   P  C  +  +D   + P++ +L K W  L   +K   FW+HEW  HGTCA+       EL+YF   +++    +++ IL    + P     Y +++    +K+   V+  ++C + K K     +  +  C   +  +I C K+  SE    R
Sbjct:    2 DWNYFTFAQQWPIAVC---AEHKSCFIPDSVVGWGIHGLWPSSDTESKGPENCNGSWPFDINNVMPLVPELKKYWPNLYPDTKANSFWEHEWSKHGTCATSLPATSNELKYFGMGLKLHAKYNISRILVNQGILPSKTAGYMINETEAAVKRELGVDAVIECVYDKEKTKKQLLYEISICLTKEFELISCNKKEVSETTCPR 200

[Close]

BLAST of Ribonuclease t2 vs. UniProt/SwissProt
Match: sp|P42815|RNS3_ARATH (Ribonuclease 3 OS=Arabidopsis thaliana OX=3702 GN=RNS3 PE=2 SV=1)

HSP 1 Score: 99.3673 bits (246), Expect = 2.094e-23
Identity = 60/196 (30.61%), Postives = 99/196 (50.51%), Query Frame = 3

Query:  141 EDWDYLVMAVEWPPSFCYTFPKKIQCC---DTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPLGNCSKD---FWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQC---THYKGKIYILAMEFCFDTKLN-IIMCP 698
            +D+D+    ++WP ++C +   +  CC          + +HGLWP+   G  P  C   S +D+ ++  +M DL +EW  L   S D   FW HEW+ HGTCA      H    YF   +++K+  +L + L    +KPD +K Y++ D  N IK+V    P ++C   + +  ++Y + +  C DT  +  I CP
Sbjct:   20 QDFDFFYFVLQWPGAYCDS---RHSCCYPQTGKPAADFGIHGLWPNYKTGGWPQNCNPDSRFDDLRVSDLMSDLQREWPTLSCPSNDGMKFWTHEWEKHGTCAESELDQH---DYFEAGLKLKQKANLLHALTNAGIKPD-DKFYEMKDIENTIKQVVGFAPGIECNKDSSHNSQLYQIYL--CVDTSASKFINCP 206

[Close]

BLAST of Ribonuclease t2 vs. TrEMBL
Match: A0A0B7A509 (Uncharacterized protein OS=Arion vulgaris OX=1028688 GN=ORF94146 PE=3 SV=1)

HSP 1 Score: 143.28 bits (360), Expect = 7.925e-37
Identity = 70/195 (35.90%), Postives = 106/195 (54.36%), Query Frame = 3

Query:  132 MKDEDWDYLVMAVEWPPSFCYTFPKKIQCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPLGNCSKD---FWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCTHYKGKIYILAMEFCFDTKLNIIMCPKRH 707
            +KDE WD+L++A  WP + C  F +  +C       GW +HGLWPS   G  P  C  +  +D  +++P+  +L K+W P  N S D    WKHEW  HGTCA    +L  EL YFN T+Q+   +D+ + L   N+ P  + +Y ++D    +   Y   P++ C H K K Y+  +  C++  LN+I CP+ H
Sbjct:   27 VKDESWDFLLLAQFWPGASCIYFDEYTECPVPQGQVGWIIHGLWPSVFSGQQPRMCDPSMTFDITEIQPLRTELDKQW-PYLNKSGDSTFLWKHEWDEHGTCAYTLPILQGELSYFNVTLQLHSTLDIFSALSTANIVPTTDNLYSLTDIWTAVVNKYTKLPQIACLHSKHKYYLDQIYLCYNKSLNLIDCPETH 220

[Close]

BLAST of Ribonuclease t2 vs. TrEMBL
Match: T1FNC2 (Uncharacterized protein OS=Helobdella robusta OX=6412 GN=20210319 PE=3 SV=1)

HSP 1 Score: 138.272 bits (347), Expect = 2.564e-35
Identity = 77/219 (35.16%), Postives = 113/219 (51.60%), Query Frame = 3

Query:  141 EDWDYLVMAVEWPPSFCYTFPKK--IQCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPL--GNCSKDFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCTHYKGKI----------YILAMEFCFDTKLNIIMCPKRHKSEDHLSRHRNKCRKP 755
            E+WD+ + ++ WP S C    +     C      T W +HGLWP+++    P+CCK A A++   L PI + L   W  L  G  + +FWKHEWK HGTCA+  + L+T+L+YFN T+ + +  ++ + L Q N+ P +N  Y VSDF      +Y V PK+ C     K           YI  +EFC D + + I CP++       SR R  C  P
Sbjct:   36 EEWDHFIFSMHWPQSICVERNETGIFNCSIPRETTSWIIHGLWPTNNTSEKPVCCKGA-AFNRSLLDPIKDQLDVHWPNLFIGQTAGEFWKHEWKKHGTCAASMESLNTQLKYFNVTLSILEKFNIASGLAQFNIVPSDNTFYTVSDFQRAFNSLYNVSPKMLCFPSSRKSKNDPKRSAYQYISEIEFCMDKQFSNIECPRKIHPN---SRPRPFCLHP 250

[Close]

BLAST of Ribonuclease t2 vs. TrEMBL
Match: Q7M439 (Ribonuclease T2 OS=Todarodes pacificus OX=6637 PE=1 SV=1)

HSP 1 Score: 137.117 bits (344), Expect = 3.274e-35
Identity = 82/235 (34.89%), Postives = 113/235 (48.09%), Query Frame = 3

Query:  135 KDEDWDYLVMAVEWPPSFCYTFPKKIQCCDT-SHVTGWNLHGLWPSS-SKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPLGNCSKD--FWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCTHYKGKI--YILAMEFCFDTKLNIIMCPKRHKSEDHLSRHRNKCRKPRNSTNPIHIPCTTGFLYQPFSP 821
            KD  +D+ V   +WPP+ C         C   S V GW +HGLWPS  +    P  C N  ++DE K+KPI  ++ K W  L   S D  FWKHEWK HGTC+  +KL   E  YFN  + + K  ++T+IL  + V P+    Y+V+DF   ++    + P + C + K     YI+ +E C D +LN I CP  H      S  RN              P + G  Y P  P
Sbjct:    1 KDTHFDFFVFTQQWPPAVCVEAQAHGHLCSIPSDVKGWVVHGLWPSRKTDRMGPFFCNNTYSFDENKIKPIEAEMRKYWPNLFADSPDLSFWKHEWKKHGTCSLSDKLTPDEFGYFNTALNLFKKYNITSILGHSGVIPNTYTAYEVNDFSTAVENALNIVPVITCIYDKMSKHHYIMQVEICIDKELNAISCPDDHSEA---SSARN-------------CPASKGIWYPPIIP 219

[Close]

BLAST of Ribonuclease t2 vs. TrEMBL
Match: L8GFB8 (Ribonuclease, T2 family OS=Acanthamoeba castellanii str. Neff OX=1257118 GN=ACA1_257540 PE=3 SV=1)

HSP 1 Score: 136.346 bits (342), Expect = 8.088e-34
Identity = 64/194 (32.99%), Postives = 105/194 (54.12%), Query Frame = 3

Query:  135 KDEDWDYLVMAVEWPPSFCYTFPKKIQCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPL--GNCSKDFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQC----THYKGKIYILAMEFCFDTKLNIIMCP 698
            +   WD+L++  +W P  C T   K QC   S+V  W LHG+WP++  GS P  C ++ +++ ++L+PI + L   W  L   N  + FW+HE++ HGTCA+ +  L TEL YFN T+  +   D++    +  ++P +NK Y +      I+  Y   P +QC    +  +G   + ++ FC  + L II CP
Sbjct:  108 QSTSWDFLLLVQQWGPGVCATSRGK-QCVIPSYVRYWTLHGMWPNNFDGSYPANCPDSESFNMQRLEPIRKSLTAYWPTLYPSNTLESFWEHEFEKHGTCAASDPTLATELAYFNATLTARATFDISVAFSKAGIQPSSNKAYSIDTISKAIQSAYGGVPLVQCSRESSRARGPEALTSIGFCISSSLTIIDCP 300

[Close]

BLAST of Ribonuclease t2 vs. TrEMBL
Match: V4APT3 (Uncharacterized protein (Fragment) OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_76871 PE=3 SV=1)

HSP 1 Score: 120.939 bits (302), Expect = 2.206e-29
Identity = 61/189 (32.28%), Postives = 102/189 (53.97%), Query Frame = 3

Query:  141 EDWDYLVMAVEWPPSFCYTF-PKKIQCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPLGNCSK--DFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYK-VEPKLQCTHYKGKIYILAMEFCFDTKLNIIMC 695
            E++D+  ++  WP + C     +K+ C +T  V GW +HGLWPS   G +P  C +   ++ K L P+M DLLK W  L   S     W+HEW  HGTCA  +    TE  +F + + + K ++++ ++   N+ P + K+Y V      +KK +  +EP + C   K K Y+  ++ C+D + N++ C
Sbjct:    3 EEFDFFTLSSAWPKTVCLEGQTEKLYCNNTLDVAGWTIHGLWPSRIDGKEPKSCGHIK-FNLKTLDPLMGDLLKLWPNLFKYSSLDSLWRHEWNKHGTCAVSDNNTATEFLFFKKALDVFKKINISRVMKNLNIVPSDTKLYSVRTISRGLKKHFSGIEPIIMCLDIKNKTYLHQIQVCYDKEFNMVDC 190

[Close]

BLAST of Ribonuclease t2 vs. Ensembl Cavefish
Match: rnaset2 (ribonuclease T2 [Source:NCBI gene;Acc:103036121])

HSP 1 Score: 92.0485 bits (227), Expect = 2.731e-21
Identity = 53/190 (27.89%), Postives = 98/190 (51.58%), Query Frame = 3

Query:  144 DWDYLVMAVEWPPSFCYTFPKKIQCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEW-NPLGNCSKDFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCTHYKGKIYILA---MEFCFDTKLNIIMCPK 701
            DW  L++   WP +FC       QC  T++ + W LHG WP+         C ++  ++   ++ ++ ++   W + L   S  FWKHEW+ HGTCA+ ++ L ++ +YF++ +++   +DL  +L ++ + P + K YK++D    I   + V PK+QC     +  +     +E C D +  +  C K
Sbjct:   25 DWTKLILTHHWPKTFCMI----DQC--TTNFSYWTLHGFWPNVGN-----MCNSSWHFNASLIEDLLPEMKTYWPDLLKPASTQFWKHEWEKHGTCAAKDEDLDSQHKYFSKALELYHKLDLDGVLKKSQIVP-SEKYYKLADLEESIVSSFGVTPKIQCVLEAKRAEVQTVGQIEICVDKQFQLTDCEK 202

[Close]

BLAST of Ribonuclease t2 vs. Ensembl Cavefish
Match: rnaset2l (ribonuclease Oy-like [Source:NCBI gene;Acc:103022964])

HSP 1 Score: 74.3294 bits (181), Expect = 5.524e-15
Identity = 40/141 (28.37%), Postives = 69/141 (48.94%), Query Frame = 3

Query:  144 DWDYLVMAVEWPPSFCYTFPKKIQCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPL--GNCSKDFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYK 560
            +W  ++  ++WP SFC +   +  C    ++  W +HGLWP  + G    CC     + +  L+ +  +L + W  L     +  FWK EW  HGTCA+  + + +   YF  +++++   D+ N L    +KP  N  YK
Sbjct:   43 NWTCMIFTIQWPGSFCLSLENRNICRIPENIHNWTIHGLWPIRTYG----CCFCWPVF-QSHLQDLEPELSQLWPSLIKSKSNFSFWKDEWFKHGTCAACVESMGSPAHYFRTSLKLRTLFDVDNALANTGIKPSCNISYK 178

[Close]

BLAST of Ribonuclease t2 vs. Ensembl Sea Lamprey
Match: rnaset2 (ribonuclease T2 [Source:NCBI gene;Acc:791890])

HSP 1 Score: 100.138 bits (248), Expect = 5.305e-25
Identity = 63/235 (26.81%), Postives = 108/235 (45.96%), Query Frame = 3

Query:  141 EDWDYLVMAVEWPPSFCYT-FPKKIQCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPLGNC-SKDFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQC--------THYKGKIYILAMEFCFDTKLNIIMCPKRHKSEDHLSRHRNKCRKPRNS-----TNPIHIPCTTGF 800
            EDW  L++   WP SFC + + +K  C   S V  W++HGLW +         C  +  +D K+++ ++  L + W  L      D WKHEW  HGTCA+  + L+++  YF++T+++ + +D++  L    V P N   YK    +      + V+ KLQC        T   G+I     + C+  + +++ C +  ++   +    +K   P N         IH P    F
Sbjct:   27 EDWSQLILTQHWPQSFCMSQWSEKHNCTIPSSVKSWSIHGLWTNHRT-----FCNKSWHFDVKEIEDLLPQLDQFWPDLEKTNGTDLWKHEWIRHGTCAATLEALNSQHNYFSKTMELYQKLDISKALSDAGVTPSNTVFYKEEQILEAFSTAFGVKAKLQCLTVPQEENTQLLGQI-----QMCWSREFSLVNCSRHAEAGIPVPNSYSKSFTPSNDIVCDPAKIIHYPLIGKF 251

[Close]

BLAST of Ribonuclease t2 vs. Ensembl Nematostella
Match: EDO48543 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJ98])

HSP 1 Score: 98.2117 bits (243), Expect = 4.997e-24
Identity = 59/217 (27.19%), Postives = 94/217 (43.32%), Query Frame = 3

Query:  132 MKDEDWDYLVMAVEWPPSFCY-------------TFPKKIQCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPLGNCSK----DFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCTHYKGKIYILA-MEFCFDTKL---NIIMCPKRHKSED 719
            ++   WDY V +  WP S CY             T       C  + VT W LHGLWP+    ++P+ C ++  + E +++ + + +++ W    + SK    D W HEWK HGTCA+       E  YF+  + +  +  L   L   N+ P +++MY V      I   Y  + ++ C        +LA +  C D      N I     H S+D
Sbjct:   22 LESHKWDYFVFSQWWPQSQCYYRNGQTMDDKWRFTSGNARNDCVPADVTTWTLHGLWPTVGGKAEPVNCNSSWPFVESEIQDLEDRMMQRWLAFPDSSKSSARDLWSHEWKKHGTCATDLAQTSNEHSYFSMALALNSNCGLLRALASENIIPSDDQMYTVKQVERAISNKYGAKGRVICLRGPDDQQLLAGIRICLDKSFRPRNCIQTYPEHCSDD 238

[Close]

BLAST of Ribonuclease t2 vs. Ensembl Nematostella
Match: EDO48544 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJ99])

HSP 1 Score: 94.7449 bits (234), Expect = 1.116e-22
Identity = 50/175 (28.57%), Postives = 80/175 (45.71%), Query Frame = 3

Query:  147 WDYLVMAVEWPPSFCY-------------TFPKKIQCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPLGNCSK----DFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQC 620
            WDY V +  WP S CY             T       C  + VT W LHGLWP+    ++P+ C ++  + E +++ + + +++ W    + SK    D W HEWK HGTCA+       E  YF+  + +  +  L   L   N+ P +++MY V      I   Y  + ++ C
Sbjct:   20 WDYFVFSQWWPQSQCYYRNGQTMDDKWRFTSGNARNDCVPADVTTWTLHGLWPTVGGKAEPVNCNSSWPFVESEIQDLEDRMMQRWLAFPDSSKSSARDLWSHEWKKHGTCATDLAETSNEHSYFSMALALNSNCGLLRALASENIIPSDDQMYTVKQVERAISNKYGAKGRVIC 194

[Close]

BLAST of Ribonuclease t2 vs. Ensembl Medaka
Match: rnaset2 (ribonuclease T2 [Source:NCBI gene;Acc:101163650])

HSP 1 Score: 102.449 bits (254), Expect = 3.300e-25
Identity = 61/194 (31.44%), Postives = 108/194 (55.67%), Query Frame = 3

Query:  147 WDYLVMAVEWPPSFCYTFPKKIQCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPLGN-CSKDFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCTH-YKGKIY--ILAMEFCFDTKLNIIMCPKRHKSE 716
            W  L++   WP +FC      ++ C  + ++ W LHGLWP   KG D   C ++  ++   ++ ++ D+ K W  L N  S  FWK+EW  HGTCA+  + L+++ +YF++ +++   +DL+++L +  + P ++K Y  S     I+ VY  +PK+QC H  KG  +  +  +E CFD+   ++ C K+   E
Sbjct:   27 WSKLILTHHWPNTFC-----SMEHCHPN-ISYWTLHGLWPD--KGMD---CNSSWHFNPSLIEDLLPDMNKSWPDLRNRSSVSFWKYEWHKHGTCAAKAESLNSQHKYFSKALELYHKLDLSSVLVKFGITP-SDKYYPFSQVEGAIENVYGFKPKIQCVHSSKGGDFQSLGQIEICFDSDFTLMDCEKQSAKE 208

[Close]

Query:  147 WDYLVMAVEWPPSFCYTFPKKIQCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPLGN-CSKDFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCTH-YKGKIY--ILAMEFCFDTKLNIIMCPKRHKSE 716
            W  L++   WP +FC      ++ C  + ++ W LHGLWP   KG D   C ++  ++   ++ ++ D+ K W  L N  S  FWK+EW  HGTCA+  + L+++ +YF++ +++   +DL+++L +  + P ++K Y  S     I+ VY  +PK+QC H  KG  +  +  +E CFD+   ++ C K+   E
Sbjct:   27 WSKLILTHHWPNTFC-----SMEHCHPN-ISYWTLHGLWPD--KGMD---CNSSWHFNPSLIEDLLPDMNKSWPDLRNRSSVSFWKYEWHKHGTCAAKAESLNSQHKYFSKALELYHKLDLSSVLVKFGITP-SDKYYPFSQVEGAIENVYGFKPKIQCVHSSKGGDFQSLGQIEICFDSDFTLMDCEKQSAKE 208

[Close]

BLAST of Ribonuclease t2 vs. Ensembl Medaka
Match: rnaset2l (ribonuclease Oy [Source:NCBI gene;Acc:101170531])

HSP 1 Score: 78.9518 bits (193), Expect = 1.563e-16
Identity = 39/164 (23.78%), Postives = 80/164 (48.78%), Query Frame = 3

Query:  138 DEDWDYLVMAVEWPPSFCYTFPKKIQCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPL--GNCSKDFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCT 623
            D  W  ++  ++WP  FC +   +  C     VT W +HGLWP  ++      C N     +  ++ + ++L++ W  L     S  FW+ EW  HG CA+  +  ++  +YF  +++++K  ++  +L    + P   + YKV++  +++      + ++QC 
Sbjct:   46 DCAWRCIIFTLQWPGGFCASLYNQTLCRIPDTVTDWTIHGLWPLHAQR-----CCNCWPMFQSDVQELKDELVENWPSLLKTKSSFQFWEQEWAKHGACAACVEGFNSPQKYFQISLKLRKWFEIQRVLEDAGIAPSCERRYKVAEVQSILTPHVGDQYEIQCV 204

[Close]

Query:  138 DEDWDYLVMAVEWPPSFCYTFPKKIQCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPL--GNCSKDFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCT 623
            D  W  ++  ++WP  FC +   +  C     VT W +HGLWP  ++      C N     +  ++ + ++L++ W  L     S  FW+ EW  HG CA+  +  ++  +YF  +++++K  ++  +L    + P   + YKV++  +++      + ++QC 
Sbjct:   46 DCAWRCIIFTLQWPGGFCASLYNQTLCRIPDTVTDWTIHGLWPLHAQR-----CCNCWPMFQSDVQELKDELVENWPSLLKTKSSFQFWEQEWAKHGACAACVEGFNSPQKYFQISLKLRKWFEIQRVLEDAGIAPSCERRYKVAEVQSILTPHVGDQYEIQCV 204

[Close]

BLAST of Ribonuclease t2 vs. Planmine SMEST
Match: SMESG000048912.1 (SMESG000048912.1)

HSP 1 Score: 494.197 bits (1271), Expect = 1.396e-178
Identity = 250/250 (100.00%), Postives = 250/250 (100.00%), Query Frame = 3

Query:   72 MFPIKYFXXXXXXXXXXXXWMKDEDWDYLVMAVEWPPSFCYTFPKKIQCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPLGNCSKDFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCTHYKGKIYILAMEFCFDTKLNIIMCPKRHKSEDHLSRHRNKCRKPRNSTNPIHIPCTTGFLYQPFSP 821
            MFPIKYFLLIILSIYTSSIWMKDEDWDYLVMAVEWPPSFCYTFPKKIQCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPLGNCSKDFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCTHYKGKIYILAMEFCFDTKLNIIMCPKRHKSEDHLSRHRNKCRKPRNSTNPIHIPCTTGFLYQPFSP
Sbjct:    1 MFPIKYFLLIILSIYTSSIWMKDEDWDYLVMAVEWPPSFCYTFPKKIQCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPLGNCSKDFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCTHYKGKIYILAMEFCFDTKLNIIMCPKRHKSEDHLSRHRNKCRKPRNSTNPIHIPCTTGFLYQPFSP 250

[Close]

BLAST of Ribonuclease t2 vs. Planmine SMEST
Match: SMESG000048912.1 (SMESG000048912.1)

HSP 1 Score: 479.174 bits (1232), Expect = 5.738e-173
Identity = 230/230 (100.00%), Postives = 230/230 (100.00%), Query Frame = 3

Query:  132 MKDEDWDYLVMAVEWPPSFCYTFPKKIQCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPLGNCSKDFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCTHYKGKIYILAMEFCFDTKLNIIMCPKRHKSEDHLSRHRNKCRKPRNSTNPIHIPCTTGFLYQPFSP 821
            MKDEDWDYLVMAVEWPPSFCYTFPKKIQCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPLGNCSKDFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCTHYKGKIYILAMEFCFDTKLNIIMCPKRHKSEDHLSRHRNKCRKPRNSTNPIHIPCTTGFLYQPFSP
Sbjct:    1 MKDEDWDYLVMAVEWPPSFCYTFPKKIQCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPLGNCSKDFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCTHYKGKIYILAMEFCFDTKLNIIMCPKRHKSEDHLSRHRNKCRKPRNSTNPIHIPCTTGFLYQPFSP 230

[Close]

BLAST of Ribonuclease t2 vs. Planmine SMEST
Match: SMESG000048912.1 (SMESG000048912.1)

HSP 1 Score: 457.988 bits (1177), Expect = 1.050e-164
Identity = 220/220 (100.00%), Postives = 220/220 (100.00%), Query Frame = 3

Query:  162 MAVEWPPSFCYTFPKKIQCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPLGNCSKDFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCTHYKGKIYILAMEFCFDTKLNIIMCPKRHKSEDHLSRHRNKCRKPRNSTNPIHIPCTTGFLYQPFSP 821
            MAVEWPPSFCYTFPKKIQCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPLGNCSKDFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCTHYKGKIYILAMEFCFDTKLNIIMCPKRHKSEDHLSRHRNKCRKPRNSTNPIHIPCTTGFLYQPFSP
Sbjct:    1 MAVEWPPSFCYTFPKKIQCCDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPLGNCSKDFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCTHYKGKIYILAMEFCFDTKLNIIMCPKRHKSEDHLSRHRNKCRKPRNSTNPIHIPCTTGFLYQPFSP 220

[Close]

BLAST of Ribonuclease t2 vs. Planmine SMEST
Match: SMESG000016389.1 (SMESG000016389.1)

HSP 1 Score: 114.775 bits (286), Expect = 1.032e-30
Identity = 63/162 (38.89%), Postives = 87/162 (53.70%), Query Frame = 3

Query:  144 DWDYLVMAVEWPPSFCYTFPKKIQC-CDTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPLGNCS--KDFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQC 620
            +WDYL   + WP +FC    K  QC  D + VTGWN+HGLWPS+  G DP  CK    ++   L  I  DL+ +W  L   +   +FW HEW  HG CA    L   EL YF+ ++Q+K+ V L  IL  N+++P ++K Y        +     V PKL+C
Sbjct:   18 NWDYLTYTLLWPQTFC----KYNQCNYDKTKVTGWNIHGLWPSNITGKDPSKCK-GDPFNINDLNSIFPDLVVQWANLLEFTNPAEFWTHEWTKHGLCAILPPLFTNELSYFSRSLQLKQFVSLDKILSDNDIQPSDDKQYDTDSVSKSVSSKLGVLPKLEC 174

[Close]

BLAST of Ribonuclease t2 vs. Planmine SMEST
Match: SMESG000046228.1 (SMESG000046228.1)

HSP 1 Score: 102.834 bits (255), Expect = 1.045e-25
Identity = 55/154 (35.71%), Postives = 82/154 (53.25%), Query Frame = 3

Query:  243 WNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPLGNCSK--DFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCTHYKGKIY-ILAMEFCFDTKLNIIMC 695
            WN+HGLWP    G+D   C       +  L  I E+LL  W  L N SK   FW +EW  HGTC+  +KL   E  YF  T+++KK++ +  +L  +N+ P+N+K Y +    N IK    + P LQC   +   + +L++  CFD  +N+  C
Sbjct:   20 WNIHGLWPYKIHGNDTFNCDGEPFQRQLVLISIYEELLLNWANLKNFSKPEKFWGYEWHKHGTCSIKDKLFSNEFGYFYHTLRLKKNISMKKLLSNHNILPNNDKAYNIQQIHNAIKVELGIIPMLQCFQKQDNEWNLLSIGICFDRSMNLKDC 173

The following BLAST results are available for this feature:

BLAST of Ribonuclease t2 vs. Ensembl Human
BLAST of Ribonuclease t2 vs. Ensembl Celegans
BLAST of Ribonuclease t2 vs. Ensembl Fly
BLAST of Ribonuclease t2 vs. Ensembl Zebrafish
BLAST of Ribonuclease t2 vs. Ensembl Xenopus
BLAST of Ribonuclease t2 vs. Ensembl Mouse
BLAST of Ribonuclease t2 vs. UniProt/SwissProt
BLAST of Ribonuclease t2 vs. TrEMBL
BLAST of Ribonuclease t2 vs. Ensembl Cavefish
BLAST of Ribonuclease t2 vs. Ensembl Sea Lamprey
BLAST of Ribonuclease t2 vs. Ensembl Yeast
BLAST of Ribonuclease t2 vs. Ensembl Nematostella
BLAST of Ribonuclease t2 vs. Ensembl Medaka
BLAST of Ribonuclease t2 vs. Planmine SMEST

BLAST of Ribonuclease t2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
RNASET2	4.091e-23	33.33	ribonuclease T2 [Source:HGNC Symbol;Acc:HGNC:21686...	[more]
RNASET2	4.383e-23	33.33	ribonuclease T2 [Source:HGNC Symbol;Acc:HGNC:21686...	[more]
RNASET2	4.383e-23	33.33	ribonuclease T2 [Source:HGNC Symbol;Acc:HGNC:21686...	[more]
RNASET2	2.733e-21	33.33	ribonuclease T2 [Source:HGNC Symbol;Acc:HGNC:21686...	[more]
AL159163.1	7.475e-18	28.73	novel protein	[more]

BLAST of Ribonuclease t2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1


Match Name	E-value	Identity	Description
rnst-2	2.514e-23	30.90	pep chromosome:WBcel235:V:1061595:1067908:1 gene:W...	[more]

BLAST of Ribonuclease t2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1


Match Name	E-value	Identity	Description
RNaseX25	3.235e-24	30.61	gene:FBgn0010406 transcript:FBtr0076752	[more]

BLAST of Ribonuclease t2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rnaset2	2.994e-25	31.63	ribonuclease T2 [Source:NCBI gene;Acc:791890]	[more]
rnaset2	2.994e-25	31.63	ribonuclease T2 [Source:NCBI gene;Acc:791890]	[more]
rnaset2	2.994e-25	31.63	ribonuclease T2 [Source:NCBI gene;Acc:791890]	[more]
rnaset2	2.994e-25	31.63	ribonuclease T2 [Source:NCBI gene;Acc:791890]	[more]
rnaset2	2.994e-25	31.63	ribonuclease T2 [Source:NCBI gene;Acc:791890]	[more]

BLAST of Ribonuclease t2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1


Match Name	E-value	Identity	Description
rnaset2	2.260e-12	30.60	ribonuclease T2 [Source:NCBI gene;Acc:780173]	[more]

BLAST of Ribonuclease t2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Rnaset2a	6.212e-25	27.23	ribonuclease T2A [Source:MGI Symbol;Acc:MGI:191544...	[more]
Rnaset2a	6.212e-25	27.23	ribonuclease T2A [Source:MGI Symbol;Acc:MGI:191544...	[more]
Gm49673	6.212e-25	27.23	predicted gene, 49673 [Source:MGI Symbol;Acc:MGI:6...	[more]
Gm49721	6.212e-25	27.23	predicted gene, 49721 [Source:MGI Symbol;Acc:MGI:6...	[more]
Rnaset2b	6.212e-25	27.23	ribonuclease T2B [Source:MGI Symbol;Acc:MGI:370208...	[more]

BLAST of Ribonuclease t2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|B8XY56\|RNT2_DANRE	2.260e-24	31.63	Ribonuclease T2 OS=Danio rerio OX=7955 GN=rnaset2 ...	[more]
sp\|C0HKG6\|RNT2B_MOUSE	4.345e-24	27.23	Ribonuclease T2-B OS=Mus musculus OX=10090 GN=Rnas...	[more]
sp\|C0HKG5\|RNT2A_MOUSE	4.345e-24	27.23	Ribonuclease T2-A OS=Mus musculus OX=10090 GN=Rnas...	[more]
sp\|Q7M456\|RNOY_CRAGI	4.470e-24	28.22	Ribonuclease Oy OS=Crassostrea gigas OX=29159 PE=1...	[more]
sp\|P42815\|RNS3_ARATH	2.094e-23	30.61	Ribonuclease 3 OS=Arabidopsis thaliana OX=3702 GN=...	[more]

BLAST of Ribonuclease t2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A0B7A509	7.925e-37	35.90	Uncharacterized protein OS=Arion vulgaris OX=10286...	[more]
T1FNC2	2.564e-35	35.16	Uncharacterized protein OS=Helobdella robusta OX=6...	[more]
Q7M439	3.274e-35	34.89	Ribonuclease T2 OS=Todarodes pacificus OX=6637 PE=...	[more]
L8GFB8	8.088e-34	32.99	Ribonuclease, T2 family OS=Acanthamoeba castellani...	[more]
V4APT3	2.206e-29	32.28	Uncharacterized protein (Fragment) OS=Lottia gigan...	[more]

BLAST of Ribonuclease t2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2


Match Name	E-value	Identity	Description
rnaset2	2.731e-21	27.89	ribonuclease T2 [Source:NCBI gene;Acc:103036121]	[more]
rnaset2l	5.524e-15	28.37	ribonuclease Oy-like [Source:NCBI gene;Acc:1030229...	[more]

BLAST of Ribonuclease t2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
rnaset2	5.305e-25	26.81	ribonuclease T2 [Source:NCBI gene;Acc:791890]	[more]

BLAST of Ribonuclease t2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Ribonuclease t2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2


Match Name	E-value	Identity	Description
EDO48543	4.997e-24	27.19	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO48544	1.116e-22	28.57	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Ribonuclease t2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4


Match Name	E-value	Identity	Description
rnaset2	3.300e-25	31.44	ribonuclease T2 [Source:NCBI gene;Acc:101163650]	[more]
rnaset2	3.300e-25	31.44	ribonuclease T2 [Source:NCBI gene;Acc:101163650]	[more]
rnaset2l	1.563e-16	23.78	ribonuclease Oy [Source:NCBI gene;Acc:101170531]	[more]
rnaset2l	1.563e-16	23.78	ribonuclease Oy [Source:NCBI gene;Acc:101170531]	[more]

BLAST of Ribonuclease t2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000048912.1	1.396e-178	100.00	SMESG000048912.1	[more]
SMESG000048912.1	5.738e-173	100.00	SMESG000048912.1	[more]
SMESG000048912.1	1.050e-164	100.00	SMESG000048912.1	[more]
SMESG000016389.1	1.032e-30	38.89	SMESG000016389.1	[more]
SMESG000046228.1	1.045e-25	35.71	SMESG000046228.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30020534 ID=SMED30020534|Name=Ribonuclease t2|organism=Schmidtea mediterranea sexual|type=transcript|length=994bp
CGAATGTTTATGAAAATATTTGAACTATATCAATATATTAGCCATTCGAT
AAACATTCATTTGAATTAAAAATGTTTCCAATCAAATATTTTTTATTGAT
CATATTGTCGATTTATACATCATCTATTTGGATGAAGGATGAAGACTGGG
ACTACCTAGTGATGGCTGTGGAATGGCCGCCTTCATTTTGCTACACTTTC
CCAAAGAAAATTCAATGCTGTGACACGTCTCATGTGACCGGATGGAACCT
TCACGGATTATGGCCATCAAGTTCGAAGGGATCAGATCCTCTTTGCTGCA
AGAATGCCAGTGCGTATGACGAGAAGAAGTTAAAGCCAATAATGGAAGAT
TTACTGAAAGAATGGAATCCTTTGGGGAATTGTTCGAAAGATTTCTGGAA
ACACGAATGGAAATTTCATGGGACTTGTGCTTCTCACAACAAGCTTCTCC
ATACGGAGCTCCAATACTTCAATGAGACCATTCAAATGAAGAAACATGTA
GATTTGACAAACATTTTACATCAGAATAATGTCAAGCCCGATAATAACAA
AATGTATAAGGTCTCGGATTTTGTCAACGTCATCAAAAAAGTGTACAAAG
TGGAGCCGAAATTGCAATGTACGCATTATAAAGGTAAAATATACATTCTT
GCCATGGAATTCTGCTTCGACACGAAACTGAACATTATAATGTGTCCAAA
GCGACATAAATCAGAGGACCATCTAAGTCGCCATAGAAACAAATGCCGCA
AACCTCGAAACAGTACAAATCCCATACATATTCCTTGCACCACAGGATTC
CTGTACCAGCCATTCAGTCCATGACATCATCATGTGTTACCATCACAGAC
ATCGGAATTTATTCATAACTGATTTATCACATTCAATATAGTAAAACACC
AGATGATTTATTTTTATTATTATTTCATTGATTCTATCATAGTGTAAATT
TCCAATTTAAATCGCGTATTACTAATACGAATATTAATAATACG

protein sequence of SMED30020534-orf-1

>SMED30020534-orf-1 ID=SMED30020534-orf-1|Name=SMED30020534-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=251bp
MFPIKYFLLIILSIYTSSIWMKDEDWDYLVMAVEWPPSFCYTFPKKIQCC
DTSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNP
LGNCSKDFWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILH
QNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCTHYKGKIYILAMEFCFD
TKLNIIMCPKRHKSEDHLSRHRNKCRKPRNSTNPIHIPCTTGFLYQPFSP
*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0016021	integral component of membrane

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000020	protonephridia
PLANA:0000070	intestinal phagocyte
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036430	RNase_T2-like_sf
IPR033697	Ribonuclease_T2_eukaryotic
IPR001568	RNase_T2-like
IPR018188	RNase_T2_His_AS_1

Vocabulary: **molecular function**
Term	Definition
GO:0003723	RNA binding
GO:0033897	ribonuclease T2 activity

Vocabulary: **biological process**
Term	Definition
GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001568	Ribonuclease T2-like	PFAM	PF00445	Ribonuclease_T2	coord: 26..208 e-value: 2.2E-44 score: 151.9
IPR001568	Ribonuclease T2-like	PANTHER	PTHR11240	RIBONUCLEASE T2	coord: 8..228
IPR036430	Ribonuclease T2-like superfamily	GENE3D	G3DSA:3.90.730.10		coord: 22..228 e-value: 5.5E-51 score: 175.3
IPR036430	Ribonuclease T2-like superfamily	SUPERFAMILY	SSF55895	Ribonuclease Rh-like	coord: 23..214
None	No IPR available	PANTHER	PTHR11240:SF22	RIBONUCLEASE T2	coord: 8..228
None	No IPR available	SIGNALP_EUK	SignalP-noTM	SignalP-noTM	coord: 1..18 score: 0.728
IPR018188	Ribonuclease T2, His active site 1	PROSITE	PS00530	RNASE_T2_1	coord: 58..65
IPR033697	Ribonuclease T2, eukaryotic	CDD	cd01061	RNase_T2_euk	coord: 26..214 e-value: 5.57586E-48 score: 155.568

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Ribonuclease t2

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 21

Owlery

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