Serine/threonine-protein phosphatase

Overview
NameSerine/threonine-protein phosphatase
Smed IDSMED30020504
Length (bp)1202
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Serine/threonine-protein phosphatase (SMED30020504) t-SNE clustered cells

Violin plots show distribution of expression levels for Serine/threonine-protein phosphatase (SMED30020504) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Serine/threonine-protein phosphatase (SMED30020504) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Serine/threonine-protein phosphatase (SMED30020504) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30020504

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30020504SMESG000000606.1 Contig939GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30020504SMESG000060548.1 Contig939GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
protonephridiaSMED30020504SMESG000060548.1 dd_Smed_v4_8385_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30020504SMESG000060548.1 dd_Smed_v4_8385_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30020504SMESG000060548.1 dd_Smed_v4_8385_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Human
Match: PPP4C (protein phosphatase 4 catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9319])

HSP 1 Score: 79.337 bits (194), Expect = 1.226e-16
Identity = 52/138 (37.68%), Postives = 69/138 (50.00%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLWILFR*NIF-IAACLQSQISR*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYPGKYLG 400
            GG++P TNYLF+        + +   L     +  Y +++ L +  NH S      Y  +DEC+RKY    VW YCT+ FD+LSLS +ID K+F VHG               D KQEV   G +CD LWS P    G
Sbjct:   69 GGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRG-NHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTG 205

HSP 2 Score: 26.9498 bits (58), Expect = 1.226e-16
Identity = 13/26 (50.00%), Postives = 18/26 (69.23%), Query Frame = 1 
Query:  424 NNLEMIFCARQ*VMEGFKR*FHETFF 501
            N+++MI  A Q VMEG+K  F+ET  
Sbjct:  229 NDIDMICRAHQLVMEGYKWHFNETVL 254
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Human
Match: PPP4C (protein phosphatase 4 catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9319])

HSP 1 Score: 79.337 bits (194), Expect = 1.226e-16
Identity = 52/138 (37.68%), Postives = 69/138 (50.00%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLWILFR*NIF-IAACLQSQISR*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYPGKYLG 400
            GG++P TNYLF+        + +   L     +  Y +++ L +  NH S      Y  +DEC+RKY    VW YCT+ FD+LSLS +ID K+F VHG               D KQEV   G +CD LWS P    G
Sbjct:   69 GGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRG-NHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTG 205

HSP 2 Score: 26.9498 bits (58), Expect = 1.226e-16
Identity = 13/26 (50.00%), Postives = 18/26 (69.23%), Query Frame = 1 
Query:  424 NNLEMIFCARQ*VMEGFKR*FHETFF 501
            N+++MI  A Q VMEG+K  F+ET  
Sbjct:  229 NDIDMICRAHQLVMEGYKWHFNETVL 254
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Human
Match: PPP4C (protein phosphatase 4 catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9319])

HSP 1 Score: 70.8626 bits (172), Expect = 3.782e-14
Identity = 39/90 (43.33%), Postives = 48/90 (53.33%), Query Frame = 2 
Query:  176 KSLNHSSTYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYPGKYLG 400
            +S   +  Y  +DEC+RKY    VW YCT+ FD+LSLS +ID K+F VHG               D KQEV   G +CD LWS P    G
Sbjct:   82 ESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTG 171

HSP 2 Score: 27.335 bits (59), Expect = 3.782e-14
Identity = 13/26 (50.00%), Postives = 18/26 (69.23%), Query Frame = 1 
Query:  424 NNLEMIFCARQ*VMEGFKR*FHETFF 501
            N+++MI  A Q VMEG+K  F+ET  
Sbjct:  195 NDIDMICRAHQLVMEGYKWHFNETVL 220
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Human
Match: PPP4C (protein phosphatase 4 catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9319])

HSP 1 Score: 70.8626 bits (172), Expect = 1.223e-13
Identity = 39/90 (43.33%), Postives = 48/90 (53.33%), Query Frame = 2 
Query:  176 KSLNHSSTYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYPGKYLG 400
            +S   +  Y  +DEC+RKY    VW YCT+ FD+LSLS +ID K+F VHG               D KQEV   G +CD LWS P    G
Sbjct:   82 ESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTG 171
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Human
Match: PPP2CB (protein phosphatase 2 catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:9300])

HSP 1 Score: 62.003 bits (149), Expect = 1.112e-10
Identity = 44/133 (33.08%), Postives = 64/133 (48.12%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLWILFR*NIFIAACLQSQIS-R*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYP 385
            GG  P+TNYLF+        +    +   ++ +  Y  ++ + +  NH S      Y  +DEC+RKY  A VW Y T  FD+L L+ L+D ++F +HG               D  QEV   G +CD LWS P
Sbjct:   25 GGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRG-NHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDP 156
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Celegans
Match: pph-4.1 (Serine/threonine-protein phosphatase 4 catalytic subunit 1 [Source:UniProtKB/Swiss-Prot;Acc:Q9XW79])

HSP 1 Score: 80.1073 bits (196), Expect = 1.223e-16
Identity = 53/133 (39.85%), Postives = 69/133 (51.88%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLWILFR*NIF-IAACLQSQISR*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYP 385
            GG +PNTNYLFL        + +   L     +  Y ++M L +  NH S      Y  +DEC+RKY  A VW +CT+ FD+LSL+ +ID K+F VHG               D KQEV   G +CD LWS P
Sbjct:   94 GGPVPNTNYLFLGDFVDRGFYSVETFLLLLALKARYPDRMMLIRG-NHESRQITQVYGFYDECLRKYGNASVWKHCTEVFDYLSLAAVIDGKVFCVHGGLSPSISTMDQIRVIDRKQEVPHDGPMCDLLWSDP 225

HSP 2 Score: 25.0238 bits (53), Expect = 1.223e-16
Identity = 15/34 (44.12%), Postives = 20/34 (58.82%), Query Frame = 1 
Query:  397 GADG--LFIRDNNLEMIFCARQ*VMEGFKR*FHE 492
            GAD    F   N +++I  A Q VMEG+K  F+E
Sbjct:  244 GADASKTFCETNGVDLICRAHQLVMEGYKWHFNE 277
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Celegans
Match: pph-4.2 (Serine/threonine-protein phosphatase 4 catalytic subunit 2 [Source:UniProtKB/Swiss-Prot;Acc:Q9XTT8])

HSP 1 Score: 72.7886 bits (177), Expect = 4.650e-14
Identity = 50/133 (37.59%), Postives = 69/133 (51.88%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLW-ILFR*NIFIAACLQSQISR*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYP 385
            GG+ PNTNYLFL   + R    +   +   + +  Y +++ L +  NH S      Y  +DEC+RKY    VW +CT+ FD+LSL+ +ID K+F VHG               D K EV   G +CD LWS P
Sbjct:   79 GGSPPNTNYLFLGDYVDRGYNSVETFILLMLLKCRYPDRITLIRG-NHESRQITQVYGFYDECVRKYGSGQVWKHCTEIFDYLSLAAVIDGKLFCVHGGLSPSIATLDQIRVLDRKIEVPHEGPMCDLLWSDP 210
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Celegans
Match: let-92 (Serine/threonine-protein phosphatase 2A catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:G5EGK8])

HSP 1 Score: 58.5362 bits (140), Expect = 2.647e-9
Identity = 44/138 (31.88%), Postives = 63/138 (45.65%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLWILFR*NIFIAACLQSQIS-R*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYPGKYLG 400
            GG  P+TNYLF+        +    +   +  +  Y +++ L +  NH S      Y  +DEC+RKY  + VW Y T  FD   L+ L+D ++F +HG               D  QEV   G +CD LWS P    G
Sbjct:   81 GGKSPDTNYLFMGDYVDRGYYSVETVSLLVCLKIRYKDRVTLLRG-NHESRQITQVYGFYDECLRKYGNSNVWKYFTDLFDCFPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGG 217
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Celegans
Match: let-92 (Serine/threonine-protein phosphatase 2A catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:G5EGK8])

HSP 1 Score: 58.5362 bits (140), Expect = 2.647e-9
Identity = 44/138 (31.88%), Postives = 63/138 (45.65%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLWILFR*NIFIAACLQSQIS-R*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYPGKYLG 400
            GG  P+TNYLF+        +    +   +  +  Y +++ L +  NH S      Y  +DEC+RKY  + VW Y T  FD   L+ L+D ++F +HG               D  QEV   G +CD LWS P    G
Sbjct:   81 GGKSPDTNYLFMGDYVDRGYYSVETVSLLVCLKIRYKDRVTLLRG-NHESRQITQVYGFYDECLRKYGNSNVWKYFTDLFDCFPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGG 217
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Celegans
Match: let-92 (Serine/threonine-protein phosphatase 2A catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:G5EGK8])

HSP 1 Score: 58.5362 bits (140), Expect = 2.647e-9
Identity = 44/138 (31.88%), Postives = 63/138 (45.65%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLWILFR*NIFIAACLQSQIS-R*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYPGKYLG 400
            GG  P+TNYLF+        +    +   +  +  Y +++ L +  NH S      Y  +DEC+RKY  + VW Y T  FD   L+ L+D ++F +HG               D  QEV   G +CD LWS P    G
Sbjct:   81 GGKSPDTNYLFMGDYVDRGYYSVETVSLLVCLKIRYKDRVTLLRG-NHESRQITQVYGFYDECLRKYGNSNVWKYFTDLFDCFPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGG 217
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Fly
Match: Pp4-19C (gene:FBgn0023177 transcript:FBtr0077325)

HSP 1 Score: 76.2554 bits (186), Expect = 7.270e-17
Identity = 52/138 (37.68%), Postives = 69/138 (50.00%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLW-ILFR*NIFIAACLQSQISR*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYPGKYLG 400
            GG++P  NYLF+   + R    +   L     +  Y +++ L +  NH S      Y  +DEC+RKY    VW YCT+ FD+LSLS +ID K+F VHG               D KQEV   G +CD LWS P    G
Sbjct:   69 GGDVPEKNYLFMGDFVDRGYYSVETFLLLLALKVRYPDRITLIRG-NHESRQITQVYGFYDECLRKYGSTAVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQYLDQIRSIDRKQEVPHDGPMCDLLWSDPEDQTG 205

HSP 2 Score: 30.0314 bits (66), Expect = 7.270e-17
Identity = 16/30 (53.33%), Postives = 20/30 (66.67%), Query Frame = 1 
Query:  412 FIRDNNLEMIFCARQ*VMEGFKR*FHETFF 501
            F R N+++MI  A Q VMEGFK  F+ET  
Sbjct:  225 FNRTNDIDMICRAHQLVMEGFKWHFNETVL 254
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Fly
Match: Pp4-19C (gene:FBgn0023177 transcript:FBtr0077324)

HSP 1 Score: 76.2554 bits (186), Expect = 7.270e-17
Identity = 52/138 (37.68%), Postives = 69/138 (50.00%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLW-ILFR*NIFIAACLQSQISR*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYPGKYLG 400
            GG++P  NYLF+   + R    +   L     +  Y +++ L +  NH S      Y  +DEC+RKY    VW YCT+ FD+LSLS +ID K+F VHG               D KQEV   G +CD LWS P    G
Sbjct:   69 GGDVPEKNYLFMGDFVDRGYYSVETFLLLLALKVRYPDRITLIRG-NHESRQITQVYGFYDECLRKYGSTAVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQYLDQIRSIDRKQEVPHDGPMCDLLWSDPEDQTG 205

HSP 2 Score: 30.0314 bits (66), Expect = 7.270e-17
Identity = 16/30 (53.33%), Postives = 20/30 (66.67%), Query Frame = 1 
Query:  412 FIRDNNLEMIFCARQ*VMEGFKR*FHETFF 501
            F R N+++MI  A Q VMEGFK  F+ET  
Sbjct:  225 FNRTNDIDMICRAHQLVMEGFKWHFNETVL 254
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Fly
Match: Pp4-19C (gene:FBgn0023177 transcript:FBtr0345017)

HSP 1 Score: 76.2554 bits (186), Expect = 7.270e-17
Identity = 52/138 (37.68%), Postives = 69/138 (50.00%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLW-ILFR*NIFIAACLQSQISR*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYPGKYLG 400
            GG++P  NYLF+   + R    +   L     +  Y +++ L +  NH S      Y  +DEC+RKY    VW YCT+ FD+LSLS +ID K+F VHG               D KQEV   G +CD LWS P    G
Sbjct:   69 GGDVPEKNYLFMGDFVDRGYYSVETFLLLLALKVRYPDRITLIRG-NHESRQITQVYGFYDECLRKYGSTAVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQYLDQIRSIDRKQEVPHDGPMCDLLWSDPEDQTG 205

HSP 2 Score: 30.0314 bits (66), Expect = 7.270e-17
Identity = 16/30 (53.33%), Postives = 20/30 (66.67%), Query Frame = 1 
Query:  412 FIRDNNLEMIFCARQ*VMEGFKR*FHETFF 501
            F R N+++MI  A Q VMEGFK  F+ET  
Sbjct:  225 FNRTNDIDMICRAHQLVMEGFKWHFNETVL 254
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Fly
Match: Pp4-19C (gene:FBgn0023177 transcript:FBtr0445386)

HSP 1 Score: 76.2554 bits (186), Expect = 7.270e-17
Identity = 52/138 (37.68%), Postives = 69/138 (50.00%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLW-ILFR*NIFIAACLQSQISR*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYPGKYLG 400
            GG++P  NYLF+   + R    +   L     +  Y +++ L +  NH S      Y  +DEC+RKY    VW YCT+ FD+LSLS +ID K+F VHG               D KQEV   G +CD LWS P    G
Sbjct:   69 GGDVPEKNYLFMGDFVDRGYYSVETFLLLLALKVRYPDRITLIRG-NHESRQITQVYGFYDECLRKYGSTAVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQYLDQIRSIDRKQEVPHDGPMCDLLWSDPEDQTG 205

HSP 2 Score: 30.0314 bits (66), Expect = 7.270e-17
Identity = 16/30 (53.33%), Postives = 20/30 (66.67%), Query Frame = 1 
Query:  412 FIRDNNLEMIFCARQ*VMEGFKR*FHETFF 501
            F R N+++MI  A Q VMEGFK  F+ET  
Sbjct:  225 FNRTNDIDMICRAHQLVMEGFKWHFNETVL 254
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Fly
Match: Pp4-19C (gene:FBgn0023177 transcript:FBtr0346620)

HSP 1 Score: 76.2554 bits (186), Expect = 7.270e-17
Identity = 52/138 (37.68%), Postives = 69/138 (50.00%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLW-ILFR*NIFIAACLQSQISR*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYPGKYLG 400
            GG++P  NYLF+   + R    +   L     +  Y +++ L +  NH S      Y  +DEC+RKY    VW YCT+ FD+LSLS +ID K+F VHG               D KQEV   G +CD LWS P    G
Sbjct:   69 GGDVPEKNYLFMGDFVDRGYYSVETFLLLLALKVRYPDRITLIRG-NHESRQITQVYGFYDECLRKYGSTAVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQYLDQIRSIDRKQEVPHDGPMCDLLWSDPEDQTG 205

HSP 2 Score: 30.0314 bits (66), Expect = 7.270e-17
Identity = 16/30 (53.33%), Postives = 20/30 (66.67%), Query Frame = 1 
Query:  412 FIRDNNLEMIFCARQ*VMEGFKR*FHETFF 501
            F R N+++MI  A Q VMEGFK  F+ET  
Sbjct:  225 FNRTNDIDMICRAHQLVMEGFKWHFNETVL 254
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Zebrafish
Match: ppp4cb (protein phosphatase 4, catalytic subunit b [Source:NCBI gene;Acc:562705])

HSP 1 Score: 79.337 bits (194), Expect = 9.936e-17
Identity = 52/138 (37.68%), Postives = 69/138 (50.00%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLWILFR*NIF-IAACLQSQISR*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYPGKYLG 400
            GG++P TNYLF+        + +   L     +  Y +++ L +  NH S      Y  +DEC+RKY    VW YCT+ FD+LSLS +ID K+F VHG               D KQEV   G +CD LWS P    G
Sbjct:   69 GGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRG-NHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTG 205

HSP 2 Score: 26.9498 bits (58), Expect = 9.936e-17
Identity = 13/26 (50.00%), Postives = 18/26 (69.23%), Query Frame = 1 
Query:  424 NNLEMIFCARQ*VMEGFKR*FHETFF 501
            N+++MI  A Q VMEG+K  F+ET  
Sbjct:  229 NDIDMICRAHQLVMEGYKWHFNETVL 254
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Zebrafish
Match: ppp4ca (protein phosphatase 4, catalytic subunit a [Source:NCBI gene;Acc:100003080])

HSP 1 Score: 76.6406 bits (187), Expect = 2.003e-15
Identity = 52/138 (37.68%), Postives = 67/138 (48.55%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLWILFR*NIF-IAACLQSQISR*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYPGKYLG 400
            GG +P TNYLF+        + +   L     +  Y +++ L +  NH S      Y   DEC RKY  A VW YCT+ FD+LSLS ++D K+F VHG               D KQEV   G +CD LWS P    G
Sbjct:   73 GGEVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRG-NHESRQITQVYGFFDECHRKYGSATVWRYCTEIFDYLSLSAIVDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTG 209

HSP 2 Score: 25.0238 bits (53), Expect = 2.003e-15
Identity = 12/24 (50.00%), Postives = 17/24 (70.83%), Query Frame = 1 
Query:  424 NNLEMIFCARQ*VMEGFKR*FHET 495
            N++ MI  A Q VMEG+K  F++T
Sbjct:  233 NDISMICRAHQLVMEGYKWHFNDT 256
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Zebrafish
Match: ppp2ca (protein phosphatase 2, catalytic subunit, alpha isozyme [Source:ZFIN;Acc:ZDB-GENE-050417-441])

HSP 1 Score: 63.5438 bits (153), Expect = 7.439e-11
Identity = 45/137 (32.85%), Postives = 61/137 (44.53%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLWILFR*NIFIAACLQSQISR*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYPGKYLG 400
            GG  P+TNYLF+        +    +   +S    + +       NH S      Y  +DEC+RKY  A VW Y T  FD+L L+ L+D ++F +HG               D  QEV   G +CD LWS P    G
Sbjct:   72 GGKSPDTNYLFMGDYVDRGYYSVETVTLLVSLKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDTQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGG 208
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Zebrafish
Match: ppp2cb (protein phosphatase 2, catalytic subunit, beta isozyme [Source:ZFIN;Acc:ZDB-GENE-040426-2487])

HSP 1 Score: 61.6178 bits (148), Expect = 7.743e-11
Identity = 44/133 (33.08%), Postives = 64/133 (48.12%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLWILFR*NIFIAACLQSQIS-R*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYP 385
            GG  P+TNYLF+        +    +   ++ +  Y  ++ + +  NH S      Y  +DEC+RKY  A VW Y T  FD+L L+ L+D ++F +HG               D  QEV   G +CD LWS P
Sbjct:    7 GGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRG-NHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDP 138
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Zebrafish
Match: zgc:56064 (zgc:56064 [Source:ZFIN;Acc:ZDB-GENE-040426-877])

HSP 1 Score: 61.6178 bits (148), Expect = 3.245e-10
Identity = 43/137 (31.39%), Postives = 61/137 (44.53%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLWILFR*NIFIAACLQSQISR*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYPGKYLG 400
            GG  P+TNYLF+        +    +   ++    + +       NH S      Y  +DEC+RKY  A VW + T  FD+L L+ L+D ++F +HG               D  QEV   G +CD LWS P    G
Sbjct:   72 GGKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRYRERVTILRGNHESRQITQVYGFYDECLRKYGNANVWKFFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGG 208
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Xenopus
Match: f2 (coagulation factor II, thrombin [Source:Xenbase;Acc:XB-GENE-481539])

HSP 1 Score: 79.337 bits (194), Expect = 5.906e-17
Identity = 52/138 (37.68%), Postives = 69/138 (50.00%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLWILFR*NIF-IAACLQSQISR*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYPGKYLG 400
            GG++P TNYLF+        + +   L     +  Y +++ L +  NH S      Y  +DEC+RKY    VW YCT+ FD+LSLS +ID K+F VHG               D KQEV   G +CD LWS P    G
Sbjct:   69 GGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRG-NHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTG 205

HSP 2 Score: 28.4906 bits (62), Expect = 5.906e-17
Identity = 14/26 (53.85%), Postives = 18/26 (69.23%), Query Frame = 1 
Query:  424 NNLEMIFCARQ*VMEGFKR*FHETFF 501
            NN++MI  A Q VMEG+K  F+ET  
Sbjct:  229 NNIDMICRAHQLVMEGYKWHFNETVL 254
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Xenopus
Match: atp13a5 (ATPase type 13A5 [Source:Xenbase;Acc:XB-GENE-12441880])

HSP 1 Score: 62.7734 bits (151), Expect = 8.054e-11
Identity = 44/137 (32.12%), Postives = 61/137 (44.53%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLWILFR*NIFIAACLQSQISR*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYPGKYLG 400
            GG  P+TNYLF+        +    +   ++    + +       NH S      Y  +DEC+RKY  A VW Y T  FD+L L+ L+D ++F +HG               D  QEV   G +CD LWS P    G
Sbjct:   72 GGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGG 208
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Xenopus
Match: atp13a5 (ATPase type 13A5 [Source:Xenbase;Acc:XB-GENE-12441880])

HSP 1 Score: 62.7734 bits (151), Expect = 1.905e-10
Identity = 44/137 (32.12%), Postives = 61/137 (44.53%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLWILFR*NIFIAACLQSQISR*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYPGKYLG 400
            GG  P+TNYLF+        +    +   ++    + +       NH S      Y  +DEC+RKY  A VW Y T  FD+L L+ L+D ++F +HG               D  QEV   G +CD LWS P    G
Sbjct:   72 GGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGG 208
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Xenopus
Match: ppp6c (uncharacterized loc100216173 [Source:Xenbase;Acc:XB-GENE-5997771])

HSP 1 Score: 56.6102 bits (135), Expect = 7.856e-9
Identity = 42/142 (29.58%), Postives = 63/142 (44.37%), Query Frame = 2 
Query:   41 WMNGGNIPNTNYLFLWIL----------FR*NIFIAACLQSQIS--R*NYFNQM*L*KSLNHSSTYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYP 385
            +  GG +P+TNY+F+             F   + + A    +I+  R N+       +S   +  Y  +DEC  KY  A  W YCTK FD L+++ LID ++  VHG               +  QE+   G  CD +WS P
Sbjct:   65 FRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNH-------ESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDP 199

HSP 2 Score: 23.0978 bits (48), Expect = 7.856e-9
Identity = 13/27 (48.15%), Postives = 17/27 (62.96%), Query Frame = 1 
Query:  412 FIRDNNLEMIFCARQ*VMEGFKR*FHE 492
            F+  NNL++I  A Q V EG+K  F E
Sbjct:  224 FVHINNLKLICRAHQLVHEGYKFMFDE 250
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Xenopus
Match: ppp6c (uncharacterized loc100216173 [Source:Xenbase;Acc:XB-GENE-5997771])

HSP 1 Score: 54.299 bits (129), Expect = 3.956e-8
Identity = 30/85 (35.29%), Postives = 41/85 (48.24%), Query Frame = 2 
Query:  176 KSLNHSSTYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYP 385
            +S   +  Y  +DEC  KY  A  W YCTK FD L+++ LID ++  VHG               +  QE+   G  CD +WS P
Sbjct:   93 ESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDP 177

HSP 2 Score: 23.483 bits (49), Expect = 3.956e-8
Identity = 13/27 (48.15%), Postives = 17/27 (62.96%), Query Frame = 1 
Query:  412 FIRDNNLEMIFCARQ*VMEGFKR*FHE 492
            F+  NNL++I  A Q V EG+K  F E
Sbjct:  202 FVHINNLKLICRAHQLVHEGYKFMFDE 228
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Mouse
Match: Ppp4c (protein phosphatase 4, catalytic subunit [Source:MGI Symbol;Acc:MGI:1891763])

HSP 1 Score: 79.337 bits (194), Expect = 8.946e-17
Identity = 52/138 (37.68%), Postives = 69/138 (50.00%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLWILFR*NIF-IAACLQSQISR*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYPGKYLG 400
            GG++P TNYLF+        + +   L     +  Y +++ L +  NH S      Y  +DEC+RKY    VW YCT+ FD+LSLS +ID K+F VHG               D KQEV   G +CD LWS P    G
Sbjct:   69 GGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRG-NHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTG 205

HSP 2 Score: 26.9498 bits (58), Expect = 8.946e-17
Identity = 13/26 (50.00%), Postives = 18/26 (69.23%), Query Frame = 1 
Query:  424 NNLEMIFCARQ*VMEGFKR*FHETFF 501
            N+++MI  A Q VMEG+K  F+ET  
Sbjct:  229 NDIDMICRAHQLVMEGYKWHFNETVL 254
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Mouse
Match: Ppp4c (protein phosphatase 4, catalytic subunit [Source:MGI Symbol;Acc:MGI:1891763])

HSP 1 Score: 79.337 bits (194), Expect = 8.946e-17
Identity = 52/138 (37.68%), Postives = 69/138 (50.00%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLWILFR*NIF-IAACLQSQISR*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYPGKYLG 400
            GG++P TNYLF+        + +   L     +  Y +++ L +  NH S      Y  +DEC+RKY    VW YCT+ FD+LSLS +ID K+F VHG               D KQEV   G +CD LWS P    G
Sbjct:   69 GGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRG-NHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTG 205

HSP 2 Score: 26.9498 bits (58), Expect = 8.946e-17
Identity = 13/26 (50.00%), Postives = 18/26 (69.23%), Query Frame = 1 
Query:  424 NNLEMIFCARQ*VMEGFKR*FHETFF 501
            N+++MI  A Q VMEG+K  F+ET  
Sbjct:  229 NDIDMICRAHQLVMEGYKWHFNETVL 254
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Mouse
Match: Ppp2ca (protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform [Source:MGI Symbol;Acc:MGI:1321159])

HSP 1 Score: 62.7734 bits (151), Expect = 1.524e-10
Identity = 44/137 (32.12%), Postives = 61/137 (44.53%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLWILFR*NIFIAACLQSQISR*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYPGKYLG 400
            GG  P+TNYLF+        +    +   ++    + +       NH S      Y  +DEC+RKY  A VW Y T  FD+L L+ L+D ++F +HG               D  QEV   G +CD LWS P    G
Sbjct:   72 GGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGG 208
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Mouse
Match: Ppp2cb (protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform [Source:MGI Symbol;Acc:MGI:1321161])

HSP 1 Score: 61.2326 bits (147), Expect = 4.865e-10
Identity = 44/133 (33.08%), Postives = 64/133 (48.12%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLWILFR*NIFIAACLQSQIS-R*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYP 385
            GG  P+TNYLF+        +    +   ++ +  Y  ++ + +  NH S      Y  +DEC+RKY  A VW Y T  FD+L L+ L+D ++F +HG               D  QEV   G +CD LWS P
Sbjct:   72 GGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRG-NHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDP 203
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Mouse
Match: Ppp6c (protein phosphatase 6, catalytic subunit [Source:MGI Symbol;Acc:MGI:1915107])

HSP 1 Score: 56.6102 bits (135), Expect = 5.331e-9
Identity = 42/142 (29.58%), Postives = 63/142 (44.37%), Query Frame = 2 
Query:   41 WMNGGNIPNTNYLFLWIL----------FR*NIFIAACLQSQIS--R*NYFNQM*L*KSLNHSSTYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYP 385
            +  GG +P+TNY+F+             F   + + A    +I+  R N+       +S   +  Y  +DEC  KY  A  W YCTK FD L+++ LID ++  VHG               +  QE+   G  CD +WS P
Sbjct:   65 FRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNH-------ESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDP 199

HSP 2 Score: 23.0978 bits (48), Expect = 5.331e-9
Identity = 13/27 (48.15%), Postives = 17/27 (62.96%), Query Frame = 1 
Query:  412 FIRDNNLEMIFCARQ*VMEGFKR*FHE 492
            F+  NNL++I  A Q V EG+K  F E
Sbjct:  224 FVHINNLKLICRAHQLVHEGYKFMFDE 250
[Close]
BLAST of Serine/threonine-protein phosphatase vs. UniProt/SwissProt
Match: sp|P32345|PP4C_YEAST (Serine/threonine-protein phosphatase 4 catalytic subunit OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=PPH3 PE=1 SV=2)

HSP 1 Score: 58.9214 bits (141), Expect = 3.361e-19
Identity = 32/80 (40.00%), Postives = 42/80 (52.50%), Query Frame = 2 
Query:  191 SSTYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYP 385
            +  Y  +DE +RKY  + VW YC + FD+LSL  +I+  +F VHG               D KQEV   G +CD LWS P
Sbjct:  118 TKVYGFYDEVVRKYGNSNVWRYCCEVFDYLSLGAIINNSIFCVHGGLSPDMTTVDEIRTIDRKQEVPHEGAMCDLLWSDP 197

HSP 2 Score: 50.447 bits (119), Expect = 3.361e-19
Identity = 25/38 (65.79%), Postives = 32/38 (84.21%), Query Frame = 3 
Query:   87 GFCSVEIFLLLLVYKVRYLDKITLIRCNYESR*ITQVH 200
            GF S+E FLLLL YK+RY D+ITLIR N+E+R IT+V+
Sbjct:   84 GFYSLESFLLLLCYKLRYPDRITLIRGNHETRQITKVY 121

HSP 3 Score: 27.335 bits (59), Expect = 3.361e-19
Identity = 13/25 (52.00%), Postives = 17/25 (68.00%), Query Frame = 1 
Query:  412 FIRDNNLEMIFCARQ*VMEGFKR*F 486
            F+  NN+E+I  A Q VMEG+K  F
Sbjct:  222 FLEKNNVELIARAHQLVMEGYKEMF 246
[Close]
BLAST of Serine/threonine-protein phosphatase vs. UniProt/SwissProt
Match: sp|Q6FM81|PP4C_CANGA (Serine/threonine-protein phosphatase 4 catalytic subunit OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) OX=284593 GN=PPH3 PE=3 SV=1)

HSP 1 Score: 57.3806 bits (137), Expect = 7.796e-19
Identity = 32/80 (40.00%), Postives = 42/80 (52.50%), Query Frame = 2 
Query:  191 SSTYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYP 385
            +  Y  +DE +RKY  + VW YC + FD+LSL  +I+  +F VHG               D KQEV   G +CD LWS P
Sbjct:  119 TKVYGFYDEVMRKYGNSNVWRYCCEVFDYLSLGAIINDSIFCVHGGLSPDITTLNEIRAIDRKQEVPHEGGMCDLLWSDP 198

HSP 2 Score: 52.7582 bits (125), Expect = 7.796e-19
Identity = 26/38 (68.42%), Postives = 33/38 (86.84%), Query Frame = 3 
Query:   87 GFCSVEIFLLLLVYKVRYLDKITLIRCNYESR*ITQVH 200
            GF S+E FLLLLVYK+RY D+ITLIR N+E+R IT+V+
Sbjct:   85 GFYSLESFLLLLVYKLRYPDRITLIRGNHETRQITKVY 122

HSP 3 Score: 25.7942 bits (55), Expect = 7.796e-19
Identity = 12/25 (48.00%), Postives = 17/25 (68.00%), Query Frame = 1 
Query:  412 FIRDNNLEMIFCARQ*VMEGFKR*F 486
            F+  NN+++I  A Q VMEG+K  F
Sbjct:  223 FLHVNNVDLIARAHQLVMEGYKEMF 247
[Close]
BLAST of Serine/threonine-protein phosphatase vs. UniProt/SwissProt
Match: sp|Q74ZR2|PP4C_ASHGO (Serine/threonine-protein phosphatase 4 catalytic subunit OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) OX=284811 GN=PPH3 PE=3 SV=2)

HSP 1 Score: 60.4622 bits (145), Expect = 1.614e-18
Identity = 33/80 (41.25%), Postives = 43/80 (53.75%), Query Frame = 2 
Query:  191 SSTYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYP 385
            +  Y  +DE IRKY  + VW YC + FD+LSL  +I+ ++F VHG               D KQEV   G +CD LWS P
Sbjct:  120 TKVYGFYDEVIRKYGNSNVWRYCCEVFDYLSLGAIINGQIFCVHGGLSPDVMTVDEIRSIDRKQEVPHEGAMCDLLWSDP 199

HSP 2 Score: 50.0618 bits (118), Expect = 1.614e-18
Identity = 25/38 (65.79%), Postives = 32/38 (84.21%), Query Frame = 3 
Query:   87 GFCSVEIFLLLLVYKVRYLDKITLIRCNYESR*ITQVH 200
            GF S+E FLLLL YK+RY D+ITLIR N+E+R IT+V+
Sbjct:   86 GFYSLESFLLLLCYKLRYPDRITLIRGNHETRQITKVY 123

HSP 3 Score: 23.8682 bits (50), Expect = 1.614e-18
Identity = 11/25 (44.00%), Postives = 16/25 (64.00%), Query Frame = 1 
Query:  412 FIRDNNLEMIFCARQ*VMEGFKR*F 486
            F+  N++ +I  A Q VMEG+K  F
Sbjct:  224 FLHRNDISLIARAHQLVMEGYKEMF 248
[Close]
BLAST of Serine/threonine-protein phosphatase vs. UniProt/SwissProt
Match: sp|Q6CNT6|PP4C_KLULA (Serine/threonine-protein phosphatase 4 catalytic subunit OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) OX=284590 GN=PPH3 PE=3 SV=1)

HSP 1 Score: 56.9954 bits (136), Expect = 3.713e-17
Identity = 30/80 (37.50%), Postives = 42/80 (52.50%), Query Frame = 2 
Query:  191 SSTYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYP 385
            +  Y  +DE +RKY  + VW YC + FD+L L  +++ K+F VHG               D K+EV   G +CD LWS P
Sbjct:  118 TKVYGFYDEVVRKYGNSNVWRYCCEVFDYLPLGAIVNNKVFCVHGGLSPDVLSINEIRTIDRKKEVPHEGAMCDLLWSDP 197

HSP 2 Score: 46.9802 bits (110), Expect = 3.713e-17
Identity = 23/38 (60.53%), Postives = 31/38 (81.58%), Query Frame = 3 
Query:   87 GFCSVEIFLLLLVYKVRYLDKITLIRCNYESR*ITQVH 200
            GF S+E FLLL+ YK+RY D+I LIR N+E+R IT+V+
Sbjct:   84 GFYSLESFLLLVCYKLRYPDRIVLIRGNHETRQITKVY 121

HSP 3 Score: 26.1794 bits (56), Expect = 3.713e-17
Identity = 12/25 (48.00%), Postives = 17/25 (68.00%), Query Frame = 1 
Query:  412 FIRDNNLEMIFCARQ*VMEGFKR*F 486
            F+  N++E+I  A Q VMEG+K  F
Sbjct:  222 FLHTNSVELIARAHQLVMEGYKEMF 246
[Close]
BLAST of Serine/threonine-protein phosphatase vs. UniProt/SwissProt
Match: sp|Q6P861|PP4C_XENTR (Serine/threonine-protein phosphatase 4 catalytic subunit OS=Xenopus tropicalis OX=8364 GN=ppp4c PE=2 SV=1)

HSP 1 Score: 79.337 bits (194), Expect = 2.395e-16
Identity = 52/138 (37.68%), Postives = 69/138 (50.00%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLWILFR*NIF-IAACLQSQISR*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYPGKYLG 400
            GG++P TNYLF+        + +   L     +  Y +++ L +  NH S      Y  +DEC+RKY    VW YCT+ FD+LSLS +ID K+F VHG               D KQEV   G +CD LWS P    G
Sbjct:   69 GGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRG-NHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTG 205

HSP 2 Score: 28.4906 bits (62), Expect = 2.395e-16
Identity = 14/26 (53.85%), Postives = 18/26 (69.23%), Query Frame = 1 
Query:  424 NNLEMIFCARQ*VMEGFKR*FHETFF 501
            NN++MI  A Q VMEG+K  F+ET  
Sbjct:  229 NNIDMICRAHQLVMEGYKWHFNETVL 254
[Close]
BLAST of Serine/threonine-protein phosphatase vs. TrEMBL
Match: A7TGZ1 (Serine/threonine-protein phosphatase OS=Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294) OX=436907 GN=Kpol_1032p37 PE=3 SV=1)

HSP 1 Score: 60.4622 bits (145), Expect = 3.754e-17
Identity = 33/80 (41.25%), Postives = 43/80 (53.75%), Query Frame = 2 
Query:  191 SSTYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYP 385
            +  Y  +DE +RKY  + VW YC + FD+LSL  +I+ K+F VHG               D KQEV   G +CD LWS P
Sbjct:  117 TKVYGFYDEVMRKYGNSNVWRYCCEVFDYLSLGAIINNKIFCVHGGLSPDVDTIDEIRAIDRKQEVPHEGAMCDLLWSDP 196

HSP 2 Score: 49.2914 bits (116), Expect = 3.754e-17
Identity = 24/38 (63.16%), Postives = 32/38 (84.21%), Query Frame = 3 
Query:   87 GFCSVEIFLLLLVYKVRYLDKITLIRCNYESR*ITQVH 200
            GF S+E FLLLL YK+RY D+I+LIR N+E+R IT+V+
Sbjct:   83 GFYSLESFLLLLCYKLRYPDRISLIRGNHETRQITKVY 120

HSP 3 Score: 28.4906 bits (62), Expect = 3.754e-17
Identity = 13/26 (50.00%), Postives = 19/26 (73.08%), Query Frame = 1 
Query:  412 FIRDNNLEMIFCARQ*VMEGFKR*FH 489
            F+R N++E+I  A Q VMEG+K  F+
Sbjct:  221 FLRTNDIELITRAHQLVMEGYKEMFN 246
[Close]
BLAST of Serine/threonine-protein phosphatase vs. TrEMBL
Match: N1P842 (Serine/threonine-protein phosphatase OS=Saccharomyces cerevisiae (strain CEN.PK113-7D) OX=889517 GN=CENPK1137D_3895 PE=3 SV=1)

HSP 1 Score: 58.9214 bits (141), Expect = 6.779e-17
Identity = 32/80 (40.00%), Postives = 42/80 (52.50%), Query Frame = 2 
Query:  191 SSTYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYP 385
            +  Y  +DE +RKY  + VW YC + FD+LSL  +I+  +F VHG               D KQEV   G +CD LWS P
Sbjct:  117 TKVYGFYDEVVRKYGNSNVWRYCCEVFDYLSLGAIINNSIFCVHGGLSPDMTTVDEIRTIDRKQEVPHEGAMCDLLWSDP 196

HSP 2 Score: 50.447 bits (119), Expect = 6.779e-17
Identity = 25/38 (65.79%), Postives = 32/38 (84.21%), Query Frame = 3 
Query:   87 GFCSVEIFLLLLVYKVRYLDKITLIRCNYESR*ITQVH 200
            GF S+E FLLLL YK+RY D+ITLIR N+E+R IT+V+
Sbjct:   83 GFYSLESFLLLLCYKLRYPDRITLIRGNHETRQITKVY 120

HSP 3 Score: 27.335 bits (59), Expect = 6.779e-17
Identity = 13/25 (52.00%), Postives = 17/25 (68.00%), Query Frame = 1 
Query:  412 FIRDNNLEMIFCARQ*VMEGFKR*F 486
            F+  NN+E+I  A Q VMEG+K  F
Sbjct:  221 FLEKNNVELIARAHQLVMEGYKEMF 245
[Close]
BLAST of Serine/threonine-protein phosphatase vs. TrEMBL
Match: B3LGJ5 (Serine/threonine-protein phosphatase OS=Saccharomyces cerevisiae (strain RM11-1a) OX=285006 GN=SCRG_00440 PE=3 SV=1)

HSP 1 Score: 58.9214 bits (141), Expect = 6.945e-17
Identity = 32/80 (40.00%), Postives = 42/80 (52.50%), Query Frame = 2 
Query:  191 SSTYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYP 385
            +  Y  +DE +RKY  + VW YC + FD+LSL  +I+  +F VHG               D KQEV   G +CD LWS P
Sbjct:  118 TKVYGFYDEVVRKYGNSNVWRYCCEVFDYLSLGAIINNSIFCVHGGLSPDMTTVDEIRTIDRKQEVPHEGAMCDLLWSDP 197

HSP 2 Score: 50.447 bits (119), Expect = 6.945e-17
Identity = 25/38 (65.79%), Postives = 32/38 (84.21%), Query Frame = 3 
Query:   87 GFCSVEIFLLLLVYKVRYLDKITLIRCNYESR*ITQVH 200
            GF S+E FLLLL YK+RY D+ITLIR N+E+R IT+V+
Sbjct:   84 GFYSLESFLLLLCYKLRYPDRITLIRGNHETRQITKVY 121

HSP 3 Score: 27.335 bits (59), Expect = 6.945e-17
Identity = 13/25 (52.00%), Postives = 17/25 (68.00%), Query Frame = 1 
Query:  412 FIRDNNLEMIFCARQ*VMEGFKR*F 486
            F+  NN+E+I  A Q VMEG+K  F
Sbjct:  222 FLEKNNVELIARAHQLVMEGYKEMF 246
[Close]
BLAST of Serine/threonine-protein phosphatase vs. TrEMBL
Match: A6ZY40 (Serine/threonine-protein phosphatase OS=Saccharomyces cerevisiae (strain YJM789) OX=307796 GN=PPH3 PE=3 SV=1)

HSP 1 Score: 58.9214 bits (141), Expect = 6.945e-17
Identity = 32/80 (40.00%), Postives = 42/80 (52.50%), Query Frame = 2 
Query:  191 SSTYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYP 385
            +  Y  +DE +RKY  + VW YC + FD+LSL  +I+  +F VHG               D KQEV   G +CD LWS P
Sbjct:  118 TKVYGFYDEVVRKYGNSNVWRYCCEVFDYLSLGAIINNSIFCVHGGLSPDMTTVDEIRTIDRKQEVPHEGAMCDLLWSDP 197

HSP 2 Score: 50.447 bits (119), Expect = 6.945e-17
Identity = 25/38 (65.79%), Postives = 32/38 (84.21%), Query Frame = 3 
Query:   87 GFCSVEIFLLLLVYKVRYLDKITLIRCNYESR*ITQVH 200
            GF S+E FLLLL YK+RY D+ITLIR N+E+R IT+V+
Sbjct:   84 GFYSLESFLLLLCYKLRYPDRITLIRGNHETRQITKVY 121

HSP 3 Score: 27.335 bits (59), Expect = 6.945e-17
Identity = 13/25 (52.00%), Postives = 17/25 (68.00%), Query Frame = 1 
Query:  412 FIRDNNLEMIFCARQ*VMEGFKR*F 486
            F+  NN+E+I  A Q VMEG+K  F
Sbjct:  222 FLEKNNVELIARAHQLVMEGYKEMF 246
[Close]
BLAST of Serine/threonine-protein phosphatase vs. TrEMBL
Match: C7GVR2 (Serine/threonine-protein phosphatase OS=Saccharomyces cerevisiae (strain JAY291) OX=574961 GN=PPH3 PE=3 SV=1)

HSP 1 Score: 58.9214 bits (141), Expect = 6.945e-17
Identity = 32/80 (40.00%), Postives = 42/80 (52.50%), Query Frame = 2 
Query:  191 SSTYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYP 385
            +  Y  +DE +RKY  + VW YC + FD+LSL  +I+  +F VHG               D KQEV   G +CD LWS P
Sbjct:  118 TKVYGFYDEVVRKYGNSNVWRYCCEVFDYLSLGAIINNSIFCVHGGLSPDMTTVDEIRTIDRKQEVPHEGAMCDLLWSDP 197

HSP 2 Score: 50.447 bits (119), Expect = 6.945e-17
Identity = 25/38 (65.79%), Postives = 32/38 (84.21%), Query Frame = 3 
Query:   87 GFCSVEIFLLLLVYKVRYLDKITLIRCNYESR*ITQVH 200
            GF S+E FLLLL YK+RY D+ITLIR N+E+R IT+V+
Sbjct:   84 GFYSLESFLLLLCYKLRYPDRITLIRGNHETRQITKVY 121

HSP 3 Score: 27.335 bits (59), Expect = 6.945e-17
Identity = 13/25 (52.00%), Postives = 17/25 (68.00%), Query Frame = 1 
Query:  412 FIRDNNLEMIFCARQ*VMEGFKR*F 486
            F+  NN+E+I  A Q VMEG+K  F
Sbjct:  222 FLEKNNVELIARAHQLVMEGYKEMF 246
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Cavefish
Match: ppp4cb (protein phosphatase 4 catalytic subunit [Source:NCBI gene;Acc:103024225])

HSP 1 Score: 78.9518 bits (193), Expect = 9.002e-17
Identity = 52/138 (37.68%), Postives = 69/138 (50.00%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLWILFR*NIF-IAACLQSQISR*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYPGKYLG 400
            GG++P TNYLF+        + +   L     +  Y +++ L +  NH S      Y  +DEC+RKY    VW YCT+ FD+LSLS +ID K+F VHG               D KQEV   G +CD LWS P    G
Sbjct:   69 GGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRG-NHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTG 205

HSP 2 Score: 26.9498 bits (58), Expect = 9.002e-17
Identity = 13/26 (50.00%), Postives = 18/26 (69.23%), Query Frame = 1 
Query:  424 NNLEMIFCARQ*VMEGFKR*FHETFF 501
            N+++MI  A Q VMEG+K  F+ET  
Sbjct:  229 NDIDMICRAHQLVMEGYKWHFNETVL 254
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Cavefish
Match: ppp4cb (protein phosphatase 4 catalytic subunit [Source:NCBI gene;Acc:103024225])

HSP 1 Score: 78.9518 bits (193), Expect = 9.002e-17
Identity = 52/138 (37.68%), Postives = 69/138 (50.00%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLWILFR*NIF-IAACLQSQISR*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYPGKYLG 400
            GG++P TNYLF+        + +   L     +  Y +++ L +  NH S      Y  +DEC+RKY    VW YCT+ FD+LSLS +ID K+F VHG               D KQEV   G +CD LWS P    G
Sbjct:   69 GGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRG-NHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTG 205

HSP 2 Score: 26.9498 bits (58), Expect = 9.002e-17
Identity = 13/26 (50.00%), Postives = 18/26 (69.23%), Query Frame = 1 
Query:  424 NNLEMIFCARQ*VMEGFKR*FHETFF 501
            N+++MI  A Q VMEG+K  F+ET  
Sbjct:  229 NDIDMICRAHQLVMEGYKWHFNETVL 254
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Cavefish
Match: ppp2cb (protein phosphatase 2, catalytic subunit, beta isozyme [Source:ZFIN;Acc:ZDB-GENE-040426-2487])

HSP 1 Score: 65.0846 bits (157), Expect = 2.299e-11
Identity = 45/137 (32.85%), Postives = 61/137 (44.53%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLWILFR*NIFIAACLQSQISR*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYPGKYLG 400
            GG  P+TNYLF+        +    +   ++    F +       NH S      Y  +DEC+RKY  A VW Y T  FD+L L+ L+D ++F +HG               D  QEV   G +CD LWS P    G
Sbjct:   72 GGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKGRFPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGG 208
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Cavefish
Match: ppp2ca (protein phosphatase 2, catalytic subunit, alpha isozyme [Source:ZFIN;Acc:ZDB-GENE-050417-441])

HSP 1 Score: 63.5438 bits (153), Expect = 5.976e-11
Identity = 45/137 (32.85%), Postives = 61/137 (44.53%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLWILFR*NIFIAACLQSQISR*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYPGKYLG 400
            GG  P+TNYLF+        +    +   +S    + +       NH S      Y  +DEC+RKY  A VW Y T  FD+L L+ L+D ++F +HG               D  QEV   G +CD LWS P    G
Sbjct:   59 GGKSPDTNYLFMGDYVDRGYYSVETVTLLVSLKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDTQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGG 195
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Cavefish
Match: ENSAMXT00000037663.1 (protein phosphatase 2 catalytic subunit alpha [Source:NCBI gene;Acc:103045214])

HSP 1 Score: 63.1586 bits (152), Expect = 1.112e-10
Identity = 44/137 (32.12%), Postives = 61/137 (44.53%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLWILFR*NIFIAACLQSQISR*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYPGKYLG 400
            GG  P+TNYLF+        +    +   ++    + +       NH S      Y  +DEC+RKY  A VW Y T  FD+L L+ L+D ++F +HG               D  QEV   G +CD LWS P    G
Sbjct:   72 GGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGG 208
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005238.1 (pep scaffold:Pmarinus_7.0:GL487052:8065:11513:-1 gene:ENSPMAG00000004764.1 transcript:ENSPMAT00000005238.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 51.9878 bits (123), Expect = 2.338e-8
Identity = 33/98 (33.67%), Postives = 51/98 (52.04%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLWILFR*NIFIAACLQSQIS-R*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG 325
            GG  P+TNYLF+        +    +   ++ +  Y  ++ + +  NH S      Y  +DEC+RKY  A VW Y T  FD L L+ L+D ++F +HG
Sbjct:   52 GGKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRYRERITILRG-NHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDFLPLTALVDRQIFCLHG 148
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Sea Lamprey
Match: ppp1cab (protein phosphatase 1, catalytic subunit, alpha isozyme b [Source:ZFIN;Acc:ZDB-GENE-030131-5512])

HSP 1 Score: 43.1282 bits (100), Expect = 1.776e-7
Identity = 29/88 (32.95%), Postives = 41/88 (46.59%), Query Frame = 2 
Query:  185 NHSST----YACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHGD---------------GKQEVADGGTLCD*LWSYPGK 391
            NH ++    Y  +DEC R+Y + L W   T  F+ L ++ ++D K+F  HG                   +V D G LCD LWS P K
Sbjct:  106 NHEASINRIYGFYDECKRRYNIKL-WKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDK 192

HSP 2 Score: 28.8758 bits (63), Expect = 1.776e-7
Identity = 13/31 (41.94%), Postives = 20/31 (64.52%), Query Frame = 3 
Query:   87 GFCSVEIFLLLLVYKVRYLDKITLIRCNYES 179
            G  S+E   LLL YK++Y +   L+R N+E+
Sbjct:   79 GKQSLETICLLLAYKIKYPENFFLLRGNHEA 109
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Sea Lamprey
Match: ppp1cb (protein phosphatase 1, catalytic subunit, beta isozyme [Source:ZFIN;Acc:ZDB-GENE-030616-609])

HSP 1 Score: 41.2022 bits (95), Expect = 6.409e-7
Identity = 26/82 (31.71%), Postives = 38/82 (46.34%), Query Frame = 2 
Query:  191 SSTYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHGD---------------GKQEVADGGTLCD*LWSYPGK 391
            +  Y  +DEC R++ + L W   T  F+ L ++ ++D K+F  HG                   +V D G LCD LWS P K
Sbjct:  117 NRIYGFYDECKRRFNIKL-WKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDK 197

HSP 2 Score: 28.8758 bits (63), Expect = 6.409e-7
Identity = 13/35 (37.14%), Postives = 22/35 (62.86%), Query Frame = 3 
Query:   96 SVEIFLLLLVYKVRYLDKITLIRCNYESR*ITQVH 200
            S+E   LLL YK++Y +   L+R N+E   I +++
Sbjct:   86 SLETICLLLAYKIKYPENFFLLRGNHECASINRIY 120
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010086.1 (pep scaffold:Pmarinus_7.0:GL479411:90249:92178:-1 gene:ENSPMAG00000009123.1 transcript:ENSPMAT00000010086.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 38.891 bits (89), Expect = 2.512e-6
Identity = 25/85 (29.41%), Postives = 38/85 (44.71%), Query Frame = 2 
Query:  191 SSTYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHGDGKQEV------------------ADGGTLCD*LWSYPGK 391
            +  Y  +DEC R++ + L W   T  F+ L ++ ++D K+F  HG    ++                   D G LCD LWS P K
Sbjct:   69 NRIYGFYDECKRRFNIKL-WKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGDAGLLCDLLWSDPDK 152

HSP 2 Score: 29.261 bits (64), Expect = 2.512e-6
Identity = 13/35 (37.14%), Postives = 22/35 (62.86%), Query Frame = 3 
Query:   96 SVEIFLLLLVYKVRYLDKITLIRCNYESR*ITQVH 200
            S+E   LLL YK++Y +   L+R N+E   I +++
Sbjct:   38 SLETICLLLAYKIKYPENFFLLRGNHECASINRIY 72
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Yeast
Match: PPH3 (Catalytic subunit of protein phosphatase PP4 complex; Pph3p and Psy2p form active complex, Psy4p may provide substrate specificity; regulates recovery from the DNA damage checkpoint, the gene conversion- and single-strand annealing-mediated pathways of meiotic double-strand break repair and efficient Non-Homologous End-Joining (NHEJ) pathway; involved in activation of Gln3p to alleviate nitrogen catabolite repression; Pph3p and Psy2p localize to foci on meiotic chromosomes [Source:SGD;Acc:S000002482])

HSP 1 Score: 58.9214 bits (141), Expect = 6.279e-21
Identity = 32/80 (40.00%), Postives = 42/80 (52.50%), Query Frame = 2 
Query:  191 SSTYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYP 385
            +  Y  +DE +RKY  + VW YC + FD+LSL  +I+  +F VHG               D KQEV   G +CD LWS P
Sbjct:  118 TKVYGFYDEVVRKYGNSNVWRYCCEVFDYLSLGAIINNSIFCVHGGLSPDMTTVDEIRTIDRKQEVPHEGAMCDLLWSDP 197

HSP 2 Score: 50.447 bits (119), Expect = 6.279e-21
Identity = 25/38 (65.79%), Postives = 32/38 (84.21%), Query Frame = 3 
Query:   87 GFCSVEIFLLLLVYKVRYLDKITLIRCNYESR*ITQVH 200
            GF S+E FLLLL YK+RY D+ITLIR N+E+R IT+V+
Sbjct:   84 GFYSLESFLLLLCYKLRYPDRITLIRGNHETRQITKVY 121

HSP 3 Score: 27.335 bits (59), Expect = 6.279e-21
Identity = 13/25 (52.00%), Postives = 17/25 (68.00%), Query Frame = 1 
Query:  412 FIRDNNLEMIFCARQ*VMEGFKR*F 486
            F+  NN+E+I  A Q VMEG+K  F
Sbjct:  222 FLEKNNVELIARAHQLVMEGYKEMF 246
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Yeast
Match: SIT4 (Ceramide-activated, type 2A-related serine-threonine phosphatase; functions in G1/S transition of mitotic cycle; controls lifespan, mitochondrial function, cell cycle progression by regulating HXK2 phosphorylation; regulator of COPII coat dephosphorylation; required for ER to Golgi traffic; interacts with Hrr25p kinase; cytoplasmic and nuclear protein that modulates functions mediated by Pkc1p including cell wall and actin cytoskeleton organization; similar to human PP6 [Source:SGD;Acc:S000002205])

HSP 1 Score: 50.0618 bits (118), Expect = 1.899e-15
Identity = 29/85 (34.12%), Postives = 39/85 (45.88%), Query Frame = 2 
Query:  176 KSLNHSSTYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYP 385
            +S   +  Y  ++EC+ KY    VW YC + FD L+L+ +ID K+  VHG                  QEV   G   D LWS P
Sbjct:  116 ESRQITQVYGFYEECLNKYGSTTVWKYCCQVFDFLTLAAIIDGKILCVHGGLSPEIRMLDQIRVLSRAQEVPHEGGFSDLLWSDP 200

HSP 2 Score: 44.669 bits (104), Expect = 1.899e-15
Identity = 22/38 (57.89%), Postives = 29/38 (76.32%), Query Frame = 3 
Query:   87 GFCSVEIFLLLLVYKVRYLDKITLIRCNYESR*ITQVH 200
            G+ S+E F LL+  KV+Y  KITL+R N+ESR ITQV+
Sbjct:   87 GYYSLETFTLLMCLKVKYPAKITLVRGNHESRQITQVY 124

HSP 3 Score: 23.483 bits (49), Expect = 1.899e-15
Identity = 13/23 (56.52%), Postives = 14/23 (60.87%), Query Frame = 1 
Query:  424 NNLEMIFCARQ*VMEGFKR*FHE 492
            N L +I  A Q VMEGFK  F E
Sbjct:  229 NGLNLIARAHQLVMEGFKYHFPE 251
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Yeast
Match: PPH21 (Catalytic subunit of protein phosphatase 2A (PP2A); functionally redundant with Pph22p; methylated at C terminus; forms alternate complexes with several regulatory subunits; involved in signal transduction and regulation of mitosis; forms nuclear foci upon DNA replication stress; PPH21 has a paralog, PPH22, that arose from the whole genome duplication [Source:SGD;Acc:S000002292])

HSP 1 Score: 56.9954 bits (136), Expect = 1.595e-9
Identity = 42/138 (30.43%), Postives = 64/138 (46.38%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLWILFR*NIFIAACLQSQIS-R*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYPGKYLG 400
            GG  P+TNYLF+        +    +   ++ +  Y +++ + +  NH S      Y  +DEC+RKY  A VW   T  FD+  ++ L+D K+F +HG               +  QEV   G +CD LWS P    G
Sbjct:  132 GGPCPDTNYLFMGDYVDRGYYSVETVSYLVAMKVRYPHRITILRG-NHESRQITQVYGFYDECLRKYGSANVWKMFTDLFDYFPITALVDNKIFCLHGGLSPMIETIDQVRELNRIQEVPHEGPMCDLLWSDPDDRGG 268
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Yeast
Match: PPH22 (Catalytic subunit of protein phosphatase 2A (PP2A); functionally redundant with Pph21p; methylated at C terminus; forms alternate complexes with several regulatory subunits; involved in signal transduction and regulation of mitosis; protein abundance increases in response to DNA replication stress; dephosphorylates Tel1p/Mec1p-phosphorylated Cdc13p to promote telomerase release from telomeres at G2/M; PPH22 has a paralog, PPH21, that arose from the whole genome duplication [Source:SGD;Acc:S000002347])

HSP 1 Score: 56.6102 bits (135), Expect = 2.198e-9
Identity = 42/138 (30.43%), Postives = 64/138 (46.38%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLWILFR*NIFIAACLQSQIS-R*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYPGKYLG 400
            GG  P+TNYLF+        +    +   ++ +  Y +++ + +  NH S      Y  +DEC+RKY  A VW   T  FD+  ++ L+D K+F +HG               +  QEV   G +CD LWS P    G
Sbjct:  140 GGPCPDTNYLFMGDYVDRGYYSVETVSYLVAMKVRYPHRITILRG-NHESRQITQVYGFYDECLRKYGSANVWKMFTDLFDYFPVTALVDNKIFCLHGGLSPMIETIDQVRDLNRIQEVPHEGPMCDLLWSDPDDRGG 276
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Yeast
Match: PPQ1 (Protein phosphatase that regulates the mating response; negatively regulates the MAP kinase signaling cascade during mating; member of the serine/threonine phosphatase PP1 family [Source:SGD;Acc:S000006100])

HSP 1 Score: 38.891 bits (89), Expect = 2.003e-8
Identity = 27/85 (31.76%), Postives = 40/85 (47.06%), Query Frame = 2 
Query:  176 KSLNHSSTYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG-------DGKQ--------EVADGGTLCD*LWSYP 385
            +S N +  Y  +DEC R+   + VW      F+ L L+ +I  K+F VHG       D KQ        ++ + G + D LWS P
Sbjct:  363 ESANVTKMYGFYDECKRRLS-SKVWKMFVDVFNTLPLAAIIQDKIFCVHGGISPDLHDMKQIEKVARPTDIPESGLVTDLLWSDP 446

HSP 2 Score: 35.8094 bits (81), Expect = 2.003e-8
Identity = 16/38 (42.11%), Postives = 26/38 (68.42%), Query Frame = 3 
Query:   87 GFCSVEIFLLLLVYKVRYLDKITLIRCNYESR*ITQVH 200
            G  S+E  LLLL YK++Y D   ++R N+ES  +T+++
Sbjct:  334 GKNSLETILLLLCYKIKYKDNFFMLRGNHESANVTKMY 371
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Nematostella
Match: EDO49936 (Serine/threonine-protein phosphatase [Source:UniProtKB/TrEMBL;Acc:A7RFC7])

HSP 1 Score: 73.9442 bits (180), Expect = 1.942e-15
Identity = 49/138 (35.51%), Postives = 69/138 (50.00%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLWILFR*NIF-IAACLQSQISR*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYPGKYLG 400
            GG++P+TNYLF+        + +   L     +  Y +++ L +  NH S      Y  +DEC++KY    VW YC + FD+LSLS +ID ++F VHG               D KQEV   G +CD LWS P    G
Sbjct:   69 GGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRG-NHESRQITQVYGFYDECLKKYGSITVWRYCAEIFDYLSLSAIIDNRVFCVHGGLSPSISTLDQIRSIDRKQEVPHDGPMCDLLWSDPEDIQG 205

HSP 2 Score: 26.1794 bits (56), Expect = 1.942e-15
Identity = 12/26 (46.15%), Postives = 18/26 (69.23%), Query Frame = 1 
Query:  424 NNLEMIFCARQ*VMEGFKR*FHETFF 501
            N++++I  A Q VMEG+K  F+ET  
Sbjct:  229 NDIDLICRAHQLVMEGYKWHFNETVL 254
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Nematostella
Match: EDO29759 (Serine/threonine-protein phosphatase [Source:UniProtKB/TrEMBL;Acc:A7T2Q5])

HSP 1 Score: 61.2326 bits (147), Expect = 1.430e-10
Identity = 44/132 (33.33%), Postives = 59/132 (44.70%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLWILFR*NIFIAACLQSQISR*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYP 385
            GG  P+TNYLF+        +    +   ++    F         NH S      Y  +DEC+RKY  A VW Y T  FD+L L+ L+D ++F +HG               D  QEV   G +CD LWS P
Sbjct:   73 GGKSPDTNYLFMGDYVDRGYYSVETVTLLVTLKVRFPHRICILRGNHESRQITQVYGFYDECLRKYGNASVWKYFTDLFDYLPLTALVDNQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDP 204
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Nematostella
Match: EDO30146 (Serine/threonine-protein phosphatase [Source:UniProtKB/TrEMBL;Acc:A7T1L8])

HSP 1 Score: 46.9802 bits (110), Expect = 5.334e-7
Identity = 30/101 (29.70%), Postives = 51/101 (50.50%), Query Frame = 2 
Query:   41 WMNGGNIPNTNYLFLWILFR*NIFIAACLQSQIS-R*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG 325
            +  GG +PNT+Y+F+        +        ++ +  + +++ L +  NH S      Y  +DEC  KY  A  W YC K FD L+++ +ID ++  VHG
Sbjct:   63 FRTGGQVPNTSYVFMGDFVDRGYYSLETFTRLLTLKAKWPDRITLLRG-NHESRQITQVYGFYDECQSKYGNANAWRYCCKVFDLLTVAAIIDGQVLCVHG 162

HSP 2 Score: 24.2534 bits (51), Expect = 5.334e-7
Identity = 13/27 (48.15%), Postives = 17/27 (62.96%), Query Frame = 1 
Query:  412 FIRDNNLEMIFCARQ*VMEGFKR*FHE 492
            F+  NNL++I  A Q V EG+K  F E
Sbjct:  174 FVHINNLKLICRAHQLVHEGYKYMFDE 200
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Nematostella
Match: EDO44648 (Serine/threonine-protein phosphatase [Source:UniProtKB/TrEMBL;Acc:A7RVJ0])

HSP 1 Score: 41.5874 bits (96), Expect = 7.211e-7
Identity = 27/82 (32.93%), Postives = 38/82 (46.34%), Query Frame = 2 
Query:  191 SSTYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHGD---------------GKQEVADGGTLCD*LWSYPGK 391
            +  Y  +DEC R+Y + L W   T  F+ L ++ ++D K+F  HG                   +V D G LCD LWS P K
Sbjct:  131 NRIYGFYDECKRRYNIKL-WKTFTDCFNCLPVAAILDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDK 211

HSP 2 Score: 28.8758 bits (63), Expect = 7.211e-7
Identity = 13/35 (37.14%), Postives = 22/35 (62.86%), Query Frame = 3 
Query:   96 SVEIFLLLLVYKVRYLDKITLIRCNYESR*ITQVH 200
            S+E   LLL YK++Y +   L+R N+E   I +++
Sbjct:  100 SLETICLLLAYKIKYPENFFLLRGNHECASINRIY 134
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Nematostella
Match: EDO38434 (Serine/threonine-protein phosphatase [Source:UniProtKB/TrEMBL;Acc:A7SD13])

HSP 1 Score: 47.3654 bits (111), Expect = 1.880e-6
Identity = 30/101 (29.70%), Postives = 51/101 (50.50%), Query Frame = 2 
Query:   41 WMNGGNIPNTNYLFLWILFR*NIFIAACLQSQIS-R*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG 325
            +  GG +PNT+Y+F+        +        ++ +  + +++ L +  NH S      Y  +DEC  KY  A  W YC K FD L+++ +ID ++  VHG
Sbjct:   63 FRTGGQVPNTSYVFMGDFVDRGYYSLETFTRLLTLKAKWPDRITLLRG-NHESRQITQVYGFYDECQSKYGNANAWRYCCKVFDLLTVAAIIDGQVLCVHG 162
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Medaka
Match: ppp4cb (protein phosphatase 4 catalytic subunit [Source:NCBI gene;Acc:101159020])

HSP 1 Score: 78.9518 bits (193), Expect = 1.996e-16
Identity = 52/138 (37.68%), Postives = 69/138 (50.00%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLWILFR*NIF-IAACLQSQISR*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYPGKYLG 400
            GG++P TNYLF+        + +   L     +  Y +++ L +  NH S      Y  +DEC+RKY    VW YCT+ FD+LSLS +ID K+F VHG               D KQEV   G +CD LWS P    G
Sbjct:   73 GGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRG-NHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTG 209

HSP 2 Score: 25.7942 bits (55), Expect = 1.996e-16
Identity = 13/26 (50.00%), Postives = 17/26 (65.38%), Query Frame = 1 
Query:  424 NNLEMIFCARQ*VMEGFKR*FHETFF 501
            N++ MI  A Q VMEG+K  F+ET  
Sbjct:  233 NDIHMICRAHQLVMEGYKWHFNETVL 258
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Medaka
Match: ENSORLT00000001163.2 (protein phosphatase 2 catalytic subunit alpha [Source:NCBI gene;Acc:101173325])

HSP 1 Score: 63.929 bits (154), Expect = 5.169e-11
Identity = 45/137 (32.85%), Postives = 61/137 (44.53%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLWILFR*NIFIAACLQSQISR*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYPGKYLG 400
            GG  P+TNYLF+        +    +   ++    F +       NH S      Y  +DEC+RKY  A VW Y T  FD+L L+ L+D ++F +HG               D  QEV   G +CD LWS P    G
Sbjct:   72 GGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRFRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDSQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGG 208
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Medaka
Match: ENSORLT00000041911.1 (protein phosphatase 2 catalytic subunit beta [Source:NCBI gene;Acc:101157601])

HSP 1 Score: 63.929 bits (154), Expect = 5.411e-11
Identity = 45/137 (32.85%), Postives = 61/137 (44.53%), Query Frame = 2 
Query:   50 GGNIPNTNYLFLWILFR*NIFIAACLQSQISR*NYFNQM*L*KSLNHSS-----TYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYPGKYLG 400
            GG  P+TNYLF+        +    +   ++    F +       NH S      Y  +DEC+RKY  A VW Y T  FD+L L+ L+D ++F +HG               D  QEV   G +CD LWS P    G
Sbjct:   72 GGKSPDTNYLFMGDYVDRGYYSVETVTLLVTLKVRFPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGG 208
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Medaka
Match: PPP6C (serine/threonine-protein phosphatase 6 catalytic subunit [Source:NCBI gene;Acc:101168723])

HSP 1 Score: 55.0694 bits (131), Expect = 3.860e-8
Identity = 41/142 (28.87%), Postives = 62/142 (43.66%), Query Frame = 2 
Query:   41 WMNGGNIPNTNYLFLWIL----------FR*NIFIAACLQSQIS--R*NYFNQM*L*KSLNHSSTYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYP 385
            +  GG +P+TNY+F+             F   + + A    +I+  R N+       +S   +  Y  +DEC  KY  A  W YC K FD L+++ LID ++  VHG               +  QE+   G  CD +WS P
Sbjct:   65 FRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNH-------ESRQITQVYGFYDECQTKYGNANAWRYCAKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDP 199
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Medaka
Match: ppp6c (serine/threonine-protein phosphatase 6 catalytic subunit [Source:NCBI gene;Acc:101171716])

HSP 1 Score: 52.7582 bits (125), Expect = 5.694e-8
Identity = 29/85 (34.12%), Postives = 41/85 (48.24%), Query Frame = 2 
Query:  176 KSLNHSSTYACHDECIRKYRLALVWIYCTKTFDHLSLSVLIDWKMFWVHG---------------DGKQEVADGGTLCD*LWSYP 385
            +S   +  Y  +DEC  KY  A  W YCTK FD L+++ L+D ++  VHG               +  QE+   G  CD +WS P
Sbjct:   93 ESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALMDEQVLCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDP 177

HSP 2 Score: 23.483 bits (49), Expect = 5.694e-8
Identity = 13/27 (48.15%), Postives = 17/27 (62.96%), Query Frame = 1 
Query:  412 FIRDNNLEMIFCARQ*VMEGFKR*FHE 492
            F+  NNL++I  A Q V EG+K  F E
Sbjct:  202 FVHINNLKLICRAHQLVHEGYKFMFDE 228
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Planmine SMEST
Match: SMESG000060548.1 (SMESG000060548.1)

HSP 1 Score: 191.045 bits (484), Expect = 1.871e-56
Identity = 93/93 (100.00%), Postives = 93/93 (100.00%), Query Frame = 1 
Query:  628 FKQNNSTISKKLPVPKDLSMENFSSISVLSGPGFIDIVHKLRPSQYQWLPFHRKFFVNNTGIKSAKFDSNFLSASHQGQKNISEKNSESVVKG 906
            FKQNNSTISKKLPVPKDLSMENFSSISVLSGPGFIDIVHKLRPSQYQWLPFHRKFFVNNTGIKSAKFDSNFLSASHQGQKNISEKNSESVVKG
Sbjct:  319 FKQNNSTISKKLPVPKDLSMENFSSISVLSGPGFIDIVHKLRPSQYQWLPFHRKFFVNNTGIKSAKFDSNFLSASHQGQKNISEKNSESVVKG 411
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Planmine SMEST
Match: SMESG000060548.1 (SMESG000060548.1)

HSP 1 Score: 190.66 bits (483), Expect = 3.552e-56
Identity = 93/93 (100.00%), Postives = 93/93 (100.00%), Query Frame = 1 
Query:  628 FKQNNSTISKKLPVPKDLSMENFSSISVLSGPGFIDIVHKLRPSQYQWLPFHRKFFVNNTGIKSAKFDSNFLSASHQGQKNISEKNSESVVKG 906
            FKQNNSTISKKLPVPKDLSMENFSSISVLSGPGFIDIVHKLRPSQYQWLPFHRKFFVNNTGIKSAKFDSNFLSASHQGQKNISEKNSESVVKG
Sbjct:  335 FKQNNSTISKKLPVPKDLSMENFSSISVLSGPGFIDIVHKLRPSQYQWLPFHRKFFVNNTGIKSAKFDSNFLSASHQGQKNISEKNSESVVKG 427
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Planmine SMEST
Match: SMESG000060548.1 (SMESG000060548.1)

HSP 1 Score: 190.66 bits (483), Expect = 1.066e-55
Identity = 93/93 (100.00%), Postives = 93/93 (100.00%), Query Frame = 1 
Query:  628 FKQNNSTISKKLPVPKDLSMENFSSISVLSGPGFIDIVHKLRPSQYQWLPFHRKFFVNNTGIKSAKFDSNFLSASHQGQKNISEKNSESVVKG 906
            FKQNNSTISKKLPVPKDLSMENFSSISVLSGPGFIDIVHKLRPSQYQWLPFHRKFFVNNTGIKSAKFDSNFLSASHQGQKNISEKNSESVVKG
Sbjct:  385 FKQNNSTISKKLPVPKDLSMENFSSISVLSGPGFIDIVHKLRPSQYQWLPFHRKFFVNNTGIKSAKFDSNFLSASHQGQKNISEKNSESVVKG 477
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Planmine SMEST
Match: SMESG000060548.1 (SMESG000060548.1)

HSP 1 Score: 188.348 bits (477), Expect = 1.054e-54
Identity = 92/92 (100.00%), Postives = 92/92 (100.00%), Query Frame = 1 
Query:  628 FKQNNSTISKKLPVPKDLSMENFSSISVLSGPGFIDIVHKLRPSQYQWLPFHRKFFVNNTGIKSAKFDSNFLSASHQGQKNISEKNSESVVK 903
            FKQNNSTISKKLPVPKDLSMENFSSISVLSGPGFIDIVHKLRPSQYQWLPFHRKFFVNNTGIKSAKFDSNFLSASHQGQKNISEKNSESVVK
Sbjct:  335 FKQNNSTISKKLPVPKDLSMENFSSISVLSGPGFIDIVHKLRPSQYQWLPFHRKFFVNNTGIKSAKFDSNFLSASHQGQKNISEKNSESVVK 426
[Close]
BLAST of Serine/threonine-protein phosphatase vs. Planmine SMEST
Match: SMESG000060548.1 (SMESG000060548.1)

HSP 1 Score: 188.348 bits (477), Expect = 4.483e-54
Identity = 92/92 (100.00%), Postives = 92/92 (100.00%), Query Frame = 1 
Query:  628 FKQNNSTISKKLPVPKDLSMENFSSISVLSGPGFIDIVHKLRPSQYQWLPFHRKFFVNNTGIKSAKFDSNFLSASHQGQKNISEKNSESVVK 903
            FKQNNSTISKKLPVPKDLSMENFSSISVLSGPGFIDIVHKLRPSQYQWLPFHRKFFVNNTGIKSAKFDSNFLSASHQGQKNISEKNSESVVK
Sbjct:  404 FKQNNSTISKKLPVPKDLSMENFSSISVLSGPGFIDIVHKLRPSQYQWLPFHRKFFVNNTGIKSAKFDSNFLSASHQGQKNISEKNSESVVK 495
The following BLAST results are available for this feature:
BLAST of Serine/threonine-protein phosphatase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PPP4C1.226e-1637.68protein phosphatase 4 catalytic subunit [Source:HG... [more]
PPP4C1.226e-1637.68protein phosphatase 4 catalytic subunit [Source:HG... [more]
PPP4C3.782e-1443.33protein phosphatase 4 catalytic subunit [Source:HG... [more]
PPP4C1.223e-1343.33protein phosphatase 4 catalytic subunit [Source:HG... [more]
PPP2CB1.112e-1033.08protein phosphatase 2 catalytic subunit beta [Sour... [more]
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BLAST of Serine/threonine-protein phosphatase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pph-4.11.223e-1639.85Serine/threonine-protein phosphatase 4 catalytic s... [more]
pph-4.24.650e-1437.59Serine/threonine-protein phosphatase 4 catalytic s... [more]
let-922.647e-931.88Serine/threonine-protein phosphatase 2A catalytic ... [more]
let-922.647e-931.88Serine/threonine-protein phosphatase 2A catalytic ... [more]
let-922.647e-931.88Serine/threonine-protein phosphatase 2A catalytic ... [more]
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BLAST of Serine/threonine-protein phosphatase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Pp4-19C7.270e-1737.68gene:FBgn0023177 transcript:FBtr0077325[more]
Pp4-19C7.270e-1737.68gene:FBgn0023177 transcript:FBtr0077324[more]
Pp4-19C7.270e-1737.68gene:FBgn0023177 transcript:FBtr0345017[more]
Pp4-19C7.270e-1737.68gene:FBgn0023177 transcript:FBtr0445386[more]
Pp4-19C7.270e-1737.68gene:FBgn0023177 transcript:FBtr0346620[more]
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BLAST of Serine/threonine-protein phosphatase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ppp4cb9.936e-1737.68protein phosphatase 4, catalytic subunit b [Source... [more]
ppp4ca2.003e-1537.68protein phosphatase 4, catalytic subunit a [Source... [more]
ppp2ca7.439e-1132.85protein phosphatase 2, catalytic subunit, alpha is... [more]
ppp2cb7.743e-1133.08protein phosphatase 2, catalytic subunit, beta iso... [more]
zgc:560643.245e-1031.39zgc:56064 [Source:ZFIN;Acc:ZDB-GENE-040426-877][more]
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BLAST of Serine/threonine-protein phosphatase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
f25.906e-1737.68coagulation factor II, thrombin [Source:Xenbase;Ac... [more]
atp13a58.054e-1132.12ATPase type 13A5 [Source:Xenbase;Acc:XB-GENE-12441... [more]
atp13a51.905e-1032.12ATPase type 13A5 [Source:Xenbase;Acc:XB-GENE-12441... [more]
ppp6c7.856e-929.58uncharacterized loc100216173 [Source:Xenbase;Acc:X... [more]
ppp6c3.956e-835.29uncharacterized loc100216173 [Source:Xenbase;Acc:X... [more]
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BLAST of Serine/threonine-protein phosphatase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ppp4c8.946e-1737.68protein phosphatase 4, catalytic subunit [Source:M... [more]
Ppp4c8.946e-1737.68protein phosphatase 4, catalytic subunit [Source:M... [more]
Ppp2ca1.524e-1032.12protein phosphatase 2 (formerly 2A), catalytic sub... [more]
Ppp2cb4.865e-1033.08protein phosphatase 2 (formerly 2A), catalytic sub... [more]
Ppp6c5.331e-929.58protein phosphatase 6, catalytic subunit [Source:M... [more]
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BLAST of Serine/threonine-protein phosphatase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P32345|PP4C_YEAST3.361e-1940.00Serine/threonine-protein phosphatase 4 catalytic s... [more]
sp|Q6FM81|PP4C_CANGA7.796e-1940.00Serine/threonine-protein phosphatase 4 catalytic s... [more]
sp|Q74ZR2|PP4C_ASHGO1.614e-1841.25Serine/threonine-protein phosphatase 4 catalytic s... [more]
sp|Q6CNT6|PP4C_KLULA3.713e-1737.50Serine/threonine-protein phosphatase 4 catalytic s... [more]
sp|Q6P861|PP4C_XENTR2.395e-1637.68Serine/threonine-protein phosphatase 4 catalytic s... [more]
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BLAST of Serine/threonine-protein phosphatase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A7TGZ13.754e-1741.25Serine/threonine-protein phosphatase OS=Vanderwalt... [more]
N1P8426.779e-1740.00Serine/threonine-protein phosphatase OS=Saccharomy... [more]
B3LGJ56.945e-1740.00Serine/threonine-protein phosphatase OS=Saccharomy... [more]
A6ZY406.945e-1740.00Serine/threonine-protein phosphatase OS=Saccharomy... [more]
C7GVR26.945e-1740.00Serine/threonine-protein phosphatase OS=Saccharomy... [more]
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BLAST of Serine/threonine-protein phosphatase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ppp4cb9.002e-1737.68protein phosphatase 4 catalytic subunit [Source:NC... [more]
ppp4cb9.002e-1737.68protein phosphatase 4 catalytic subunit [Source:NC... [more]
ppp2cb2.299e-1132.85protein phosphatase 2, catalytic subunit, beta iso... [more]
ppp2ca5.976e-1132.85protein phosphatase 2, catalytic subunit, alpha is... [more]
ENSAMXT00000037663.11.112e-1032.12protein phosphatase 2 catalytic subunit alpha [Sou... [more]
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BLAST of Serine/threonine-protein phosphatase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 4
Match NameE-valueIdentityDescription
ENSPMAT00000005238.12.338e-833.67pep scaffold:Pmarinus_7.0:GL487052:8065:11513:-1 g... [more]
ppp1cab1.776e-732.95protein phosphatase 1, catalytic subunit, alpha is... [more]
ppp1cb6.409e-731.71protein phosphatase 1, catalytic subunit, beta iso... [more]
ENSPMAT00000010086.12.512e-629.41pep scaffold:Pmarinus_7.0:GL479411:90249:92178:-1 ... [more]
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BLAST of Serine/threonine-protein phosphatase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
PPH36.279e-2140.00Catalytic subunit of protein phosphatase PP4 compl... [more]
SIT41.899e-1534.12Ceramide-activated, type 2A-related serine-threoni... [more]
PPH211.595e-930.43Catalytic subunit of protein phosphatase 2A (PP2A)... [more]
PPH222.198e-930.43Catalytic subunit of protein phosphatase 2A (PP2A)... [more]
PPQ12.003e-831.76Protein phosphatase that regulates the mating resp... [more]
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BLAST of Serine/threonine-protein phosphatase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO499361.942e-1535.51Serine/threonine-protein phosphatase [Source:UniP... [more]
EDO297591.430e-1033.33Serine/threonine-protein phosphatase [Source:UniP... [more]
EDO301465.334e-729.70Serine/threonine-protein phosphatase [Source:UniP... [more]
EDO446487.211e-732.93Serine/threonine-protein phosphatase [Source:UniP... [more]
EDO384341.880e-629.70Serine/threonine-protein phosphatase [Source:UniP... [more]
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BLAST of Serine/threonine-protein phosphatase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ppp4cb1.996e-1637.68protein phosphatase 4 catalytic subunit [Source:NC... [more]
ENSORLT00000001163.25.169e-1132.85protein phosphatase 2 catalytic subunit alpha [Sou... [more]
ENSORLT00000041911.15.411e-1132.85protein phosphatase 2 catalytic subunit beta [Sour... [more]
PPP6C3.860e-828.87serine/threonine-protein phosphatase 6 catalytic s... [more]
ppp6c5.694e-834.12serine/threonine-protein phosphatase 6 catalytic s... [more]
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BLAST of Serine/threonine-protein phosphatase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000060548.11.871e-56100.00SMESG000060548.1[more]
SMESG000060548.13.552e-56100.00SMESG000060548.1[more]
SMESG000060548.11.066e-55100.00SMESG000060548.1[more]
SMESG000060548.11.054e-54100.00SMESG000060548.1[more]
SMESG000060548.14.483e-54100.00SMESG000060548.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30020504 ID=SMED30020504|Name=Serine/threonine-protein phosphatase|organism=Schmidtea mediterranea sexual|type=transcript|length=1202bp
TTAAATGAATGATAAAATAGATGACTAGGGTGGATAAAAATGGATGAACG
GTGGAAATATTCCGAACACAAATTATTTGTTTCTATGGATTTTGTTCCGT
TGAAATATTTTTATTGCTGCTTGTCTACAAAGTCAGATATCTAGATAAAA
TTACTTTAATCAGATGTAATTATGAAAGTCGTTAAATCACTCAAGTACAT
ATGCATGTCATGATGAATGTATTAGAAAGTACAGATTAGCTTTAGTATGG
ATATATTGCACAAAAACATTTGATCATCTTAGTTTATCAGTTTTAATAGA
TTGGAAAATGTTTTGGGTTCACGGAGATGGCAAGCAAGAAGTCGCTGACG
GTGGAACCTTGTGTGATTGATTGTGGTCATATCCTGGAAAATACCTGGGG
CTGATGGATTATTCATCCGTGATAATAATCTAGAAATGATTTTTTGTGCG
CGTCAATAGGTTATGGAAGGTTTCAAGCGGTAATTCCACGAAACATTTTT
TTACGCCAAGGGATGGATCGTATGAATTAATAAACAGGGAATCTTCTGGA
AAGAAATTATCAAATAATATACCCAATTACCCAACCTGCTAATTAGGAAA
AGTCTTTTCTACGTGTATAAAGCGTAGTTCAAACAAAACAATTCTACAAT
AAGTAAGAAACTGCCTGTTCCCAAAGATTTATCCATGGAAAATTTCTCAT
CAATATCAGTGCTAAGCGGTCCTGGATTCATTGATATAGTTCACAAATTG
CGGCCCTCCCAGTACCAATGGCTGCCTTTTCATCGCAAATTCTTTGTCAA
CAATACCGGAATAAAATCTGCAAAGTTTGATTCCAACTTTCTCAGTGCAT
CACACCAAGGACAGAAAAATATATCAGAAAAGAATTCTGAATCGGTTGTT
AAAGGTGAAATTAAAAGTTTTCGATCGAAAATGATACAAGGACTTTATGA
GTTCAATCGAAATCCGAAAATTGCCGATAATTCAAACTTCAAATGAACAA
CATTTAATGCAAGTTTCTGAAATTAAGAAAGTTACAGATAAACGAAAAAT
TATTCAAGACTTCGAGATCGAAGAAAGCCAAACATAATGAGGACGGAAAT
GCAAATACAGTGAAAAGTTCAATCCACGAGTCAGACGATGTATTTTTTGA
CAGTGATTAAATCATTAAATCCGATGTACAAAAATGAACCGAACCACACA
TG
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protein sequence of SMED30020504-orf-1

>SMED30020504-orf-1 ID=SMED30020504-orf-1|Name=SMED30020504-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=104bp
MENFSSISVLSGPGFIDIVHKLRPSQYQWLPFHRKFFVNNTGIKSAKFDS
NFLSASHQGQKNISEKNSESVVKGEIKSFRSKMIQGLYEFNRNPKIADNS
NFK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000020protonephridia
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR029052Metallo-depent_PP-like
Vocabulary: molecular function
TermDefinition
GO:0004721phosphoprotein phosphatase activity
GO:0016787hydrolase activity
Vocabulary: biological process
TermDefinition
GO:0006470protein dephosphorylation