MFS domain-containing protein
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30020480 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 6
Homology
BLAST of MFS domain-containing protein vs. Ensembl Zebrafish
Match: rpz3 (rapunzel 3 [Source:ZFIN;Acc:ZDB-GENE-030131-4784]) HSP 1 Score: 67.0106 bits (162), Expect = 1.166e-11 Identity = 68/282 (24.11%), Postives = 123/282 (43.62%), Query Frame = 3 Query: 207 PLLKSIGYFSKVIMAQFETESKELTYMKEQFKIINDKMDTVDQQFDEVKKAINWNVVKVQYFNHETAIGLLQDMILSISDAPSNVRQMMMDRFRITYDQTYYNAADK----LYESFTNPQRIFSENLVTASCQTFNFHRRKVEKFFLGNIQLILKG-LEVESFYLTTKNLTSNQDYWAEQWNKKINQISAIMEETINSIKGNWHSQLQKDAEEFNVKNYGKGNKEYLEEFYNFLTDKFSWREWFLVVYNPITGGDNHYVSVYGGIINLRSRGHNIAVASRDK 1037 PL ++ K+++ ESKE+TY+K+QF ++ K+D + Q ++ I + Q+F+ E + + I +A +++ + R+ D + +K LY++ F E ++ Q +RR +E F + +L+ G + + + T+ + Q+ E W+ KI +I M+ETI ++ Q + D + + +E E +FLT KF W W + V +S G I NLR+ G N S K Sbjct: 39 PLFEAAAPVLKLVLNN--VESKEVTYVKDQFLVVRSKLDVLSCQLQDIDSEIRRRRLDTQFFSVEENMRNQFRKYIDILEAKPEYKEV---KKRLFLDHFFITGGEKNLCLLYDAVMG-NSTFGEPILEVVEQYEARNRRVLEDFCVRLKELLCLGIIALLGYCFLTQGEEAEQEKIQE-WSTKIQEIETKMKETIEKCVQSFPEQAELDIKRLLKEKEEANLQETARELLDFLTKKFDWVCWSIRV-----------ISNMGKISNLRA-GQNFQCVSGQK 301
BLAST of MFS domain-containing protein vs. Ensembl Zebrafish
Match: rpz6 (rapunzel 6 [Source:ZFIN;Acc:ZDB-GENE-170530-5]) HSP 1 Score: 63.5438 bits (153), Expect = 1.470e-10 Identity = 66/264 (25.00%), Postives = 113/264 (42.80%), Query Frame = 3 Query: 261 TESKELTYMKEQFKIINDKMDTVDQQFDEVKKAINWNVVKVQYFNHETAIGLLQDMILSISDAPSNVRQMMMDRFRITYDQTYYNAADK----LYESFTNPQRIFSENLVTASCQTFNFHRRKVEKFFLGNIQLILKG-LEVESFYLTTKNLTSNQDYWAEQWNKKINQISAIMEETINSIKGNWHSQLQKDAEEFNVKNYGKGNKEYLEEFYNFLTDKFSWREWFLVVYNPITGGDNHYVSVYGGIINLRSRGHNIAVASRDK 1037 ESKE+TY+K+QF ++ K+D + Q +++ I + Q+F E I + I +A +++ R R+ +K LY++ F E ++ Q +RR +E F + +L+ G + + + T+ + Q+ E W+ KI +I M+ETI ++ Q + D + + +E E +FLT KF W W + V +S G I NLR+ G N S K Sbjct: 55 VESKEVTYVKDQFLVVRSKLDVLSSQIEDINCEIKKGRLDSQFFTVEENICNQFRKYIDILEAKPEYKEV---RKRLFLQHFPKTGGEKNLYMLYDAVMG-NSTFGEPILEVVEQYEARNRRVLEDFCVRLKELLCLGIIALLGYCFLTQGEEAEQEKIQE-WSTKIEEIETKMKETIEKCVQSFPEQAELDIKRLLKEKEEANLQETARELLDFLTKKFDWVCWSIRV-----------ISNMGKISNLRA-GQNFQCVSGQK 301
BLAST of MFS domain-containing protein vs. Ensembl Zebrafish
Match: rpz4 (rapunzel 4 [Source:ZFIN;Acc:ZDB-GENE-050417-472]) HSP 1 Score: 54.299 bits (129), Expect = 1.343e-7 Identity = 53/235 (22.55%), Postives = 103/235 (43.83%), Query Frame = 3 Query: 261 TESKELTYMKEQFKIINDKMDTVDQQFDEVKKAINWNVVKVQYFNHETAIGLLQDMILSISDAPSNVRQMMMDRFRITYDQTYYNAADK----LYESFTNPQRIFS-ENLVTASCQTFNFHRRKVEKFFLGNIQLILKGLEVESFYLTTKNLTSNQDYWAEQWNKKINQISAIMEETINSIKGNWHSQLQKDAEEFNVKNYGKGNKEYLEEFYNFLTDKFSWREWFLVVYNPITG 950 ESKE YMKEQF+ + D+++ V ++ ++ + I + V YF E + + + +A R++ F +++T DK LY + T FS E+++ + RR VE++ +L GL + K ++ ++W++K+ + + M I ++ +Q + DA+ K N++ + L K+ W W + ++N TG Sbjct: 55 VESKEAEYMKEQFQKVRDRLEVVSEEVQQINQEIKKSGVDATYFTVEENLTNQFRKFMDVLNAKPKFREVRKKTFLDHFNRT---GGDKNLHTLYSAVTGDN--FSGESVLEITLNYEQKSRRAVEEYCATLKKLFCVGLIALLGHAALKG-DDEEEKLLQEWSEKMKVVQSKMIVVIEDCINSFPTQSELDAKRIVRDQSDKSNQQLADMLVEHLKKKYDWVCWSVRIFNSPTG 283
BLAST of MFS domain-containing protein vs. TrEMBL
Match: V4B6X2 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_237783 PE=4 SV=1) HSP 1 Score: 158.303 bits (399), Expect = 8.072e-40 Identity = 96/304 (31.58%), Postives = 152/304 (50.00%), Query Frame = 3 Query: 207 PLLKSIGYFSKVIMAQF-ETESKELTYMKEQFKIINDKMDTVDQQFDEVKKAINWNVVKVQYFNHETAIGLLQDMILSISDAPSNVRQMMMDRFRITYDQTYYNAADKLYESFTNPQRIFSENLVTASCQTFNFHRRKVEKFFLGNIQLILKGLEVESFYLTTKNLTSNQDYWAEQWNKKINQISAIMEETINSIKGNWHSQLQKDAEEFNVKN--YGKGNKEYLEEFYNFLTDKFSWREWFLVVYNPITGGDNHYVSVYGGIINLRSRGHNIAVASRDKEDNNFNSNLISQVLDNL----PRS 1097 P L +G F IM F +ES EL +K + ++++ D VD QF EVK+ I+W+ +++QY + E I + +I + F ++ Y N+ KLY+ N R+F + L TA + + R K + F LG +QL++K ++E Y K T+ + QW + I M T NSI +H+Q KD + + +K+ N ++ Y FLT K+SWR+W + YN ITG + HYV GG + R+ G N+ VAS D+ + N V++N+ PR+ Sbjct: 62 PFLGIVGPFVSFIMGFFGHSESAELKAIKRLYTEVDNRFDKVDLQFIEVKRLIDWSKIQIQYSDIEQKINAVNQEFENIYKFSIGAVKTTASAFVKNFESDYQNSGSKLYDGIMNEGRVFGDGLFTAIIKYSEYDRGKSQTFMLGLLQLLMKAAKLELTYHQLKGHTAALHDYQNQWRTRFTHIRIKMMSTDNSIVSQYHTQSGKDIDNYLIKHPKNTMNNNDFNNMLYGFLTKKYSWRDWLTITYNDITGSNVHYVGECGGYLKFRNHGRNVVVASVDRRKGHINMAQAQSVVNNVDSCHPRT 365
BLAST of MFS domain-containing protein vs. TrEMBL
Match: A0A267E0I7 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig026172g1 PE=4 SV=1) HSP 1 Score: 157.532 bits (397), Expect = 1.687e-39 Identity = 104/351 (29.63%), Postives = 164/351 (46.72%), Query Frame = 3 Query: 261 TESKELTYMKEQFKIINDKMDTVDQQFDEVKKAINWNVVKVQYFNHETAIGLLQDMILSISDAPSNVRQMMMDRFRITYDQTYYNAADKLYESFTNPQRIFSENLVTASCQTFNFHRRKVEKFFLGNIQLILKGLEVESFYLTTKNLTSNQDYWAEQWNKKINQISAIMEETINSIKGNWHSQLQKDAEEFNVKNYGKGNKEYLEEFYNFLTDKFSWREWFLVVYNPITGGDNHYVSVYGGIINLRSRG-HNIAVASRDKEDNNFNSNLISQVLDNLPR----SFNTKGKGLAESLLMDQLIPAIQRVHKYSLAAVIEWGAGVWFISNNQFRAYKKYTGPRGRTYNIIVMG 1298 TES E+ +++EQF ++ K+D++ Q D+VK+ I W +V Y N+ET I ++ + AP + R+++ +F + A KLY++ + +ENL A HRR V F L +LI++G ++E Y + + WN ++ ++ M N IK +HSQ+ D + N NK++ Y FL DKF R WF + Y ++GGD H+VS GG + R+ G N+ VAS DK + F+ + LD+ R S L S + + A + I WG VWF + Y+K + RG N I+ G Sbjct: 117 TESAEMKFLREQFAQVHAKLDSISLQLDDVKRLIEWRTTRVMYANYETFIIAASSILNNYVAAPESSREVLKRQFIAAFQHNPL-APLKLYQAIVEKDFVIAENLAAAVVHYTQNHRRHVINFLLAMQRLIMRGAQLEIAYEKMVHGDGAGNVAKTVWNGRMEKLLIRMMRLENEIKSKYHSQMTSDIGGVILNNRHLSNKDFSGHMYRFLADKFDHRNWFSLAYKDVSGGDKHWVSFCGGDLRFRTHGSRNVVVASADKRSSRFSQPRGNAALDDAQRVGSGSHAESWTNLIRSKIGNSCADA-------AFVGSICWGCDVWFTMRSDRYVYRKMSN-RG-DINTIIFG 457
BLAST of MFS domain-containing protein vs. TrEMBL
Match: V4AXV0 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_238695 PE=4 SV=1) HSP 1 Score: 155.992 bits (393), Expect = 4.726e-39 Identity = 101/318 (31.76%), Postives = 156/318 (49.06%), Query Frame = 3 Query: 162 SDFV---KTTQAISKWGL---PLLKSIGYFSKVIMAQF-ETESKELTYMKEQFKIINDKMDTVDQQFDEVKKAINWNVVKVQYFNHETAIGLLQDMILSISDAPSNVRQMMMDRFRITYDQTYYNAADKLYESFTNPQRIFSENLVTASCQTFNFHRRKVEKFFLGNIQLILKGLEVESFYLTTKNLTSNQDYWAEQWNKKINQISAIMEETINSIKGNWHSQLQKDAEEFNVKN--YGKGNKEYLEEFYNFLTDKFSWREWFLVVYNPITGGDNHYVSVYGGIINLRSRGHNIAVASRDKEDNNFNSNLISQVLDNL 1088 DFV K T I K P L +G F IM F ++ES EL +K + ++++ D VD QF EVK+ I+W+ ++VQY + E I + +I + + F Y+ Y N+ KLY+ N R+F + L TA + + R K + F LG +QL++K ++E Y K + + QW + I M T +SI +H+Q KD + + +K+ N ++ Y FL+ K+ WR+WF V YN ITG + HYV GG I R+ G N+ VAS D + N +++N+ Sbjct: 41 GDFVVAKKFTNVIGKLATAVTPFLGIVGPFVSFIMGFFGQSESAELKAIKRLYTEVDNRFDKVDLQFIEVKRMIDWSKIQVQYSDIEQKINAVNKAFENIYKFSTAAVKTTTSAFVSNYESDYQNSGSKLYDGIMNEGRVFGDGLFTAVVKYSEYDRVKSQTFMLGLLQLLMKAAKLELTYHQLKGHKAALHDYQNQWRTRFTHIRIKMMSTDSSIVSQYHTQSGKDIDNYLIKHQKNTMNNNDFNNALYAFLSKKYFWRDWFTVTYNDITGSNVHYVGECGGHIKFRNHGRNVVVASVDSRKGHINMGQALSIVNNV 358
BLAST of MFS domain-containing protein vs. TrEMBL
Match: A0A1I8HMN9 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 158.688 bits (400), Expect = 5.078e-38 Identity = 97/325 (29.85%), Postives = 153/325 (47.08%), Query Frame = 3 Query: 261 TESKELTYMKEQFKIINDKMDTVDQQFDEVKKAINWNVVKVQYFNHETAIGLLQDMILSISDAPSNVRQMMMDRFRITYDQTYYNAADKLYESFTNPQRIFSENLVTASCQTFNFHRRKVEKFFLGNIQLILKGLEVESFYLTTKNLTSNQDYWAEQWNKKINQISAIMEETINSIKGNWHSQLQKDAEEFNVKNYGKGNKEYLEEFYNFLTDKFSWREWFLVVYNPITGGDNHYVSVYGGIINLRSRG-HNIAVASRDKEDNNFNSNLISQVLDNLPR----SFNTKGKGLAESLLMDQLIPAIQRVHKYSLAAVIEWGAGVWF 1220 TES E+ +++EQF ++ K+D++ Q D+VK+ I W +V Y N+ET I ++ + AP + R+++ +F + A KLY++ + +ENL A HRR V F L +LI++G ++E Y + + WN ++ ++ M N IK +HSQ+ D + N NK++ Y FL DKF R WF + Y ++GGD H+VS GG + R+ G N+ VAS DK + F+ + LD+ R S L S + + A + I WG VWF Sbjct: 1443 TESAEMKFLREQFAQVHAKLDSISLQLDDVKRLIEWRTTRVMYANYETFIIAASSILNNYVAAPESSREVLKRQFIAAFQHNPL-APLKLYQAIVEKDFVIAENLAAAVVHYTQNHRRHVINFLLAMQRLIMRGAQLEIAYEKMVHGDGAGNVAKTVWNGRMEKLLIRMMRLENEIKSKYHSQMTSDIGGVILNNRHLSNKDFSGHMYRFLADKFDHRNWFSLAYKDVSGGDKHWVSFCGGDLRFRTHGSRNVVVASADKRSSRFSQPRGNAALDDAQRVGSGSHAESWTNLIRSKIGNSCADA-------AFVGSICWGCDVWF 1759
BLAST of MFS domain-containing protein vs. TrEMBL
Match: A0A1I8HCC0 (MFS domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 158.688 bits (400), Expect = 5.684e-38 Identity = 97/325 (29.85%), Postives = 153/325 (47.08%), Query Frame = 3 Query: 261 TESKELTYMKEQFKIINDKMDTVDQQFDEVKKAINWNVVKVQYFNHETAIGLLQDMILSISDAPSNVRQMMMDRFRITYDQTYYNAADKLYESFTNPQRIFSENLVTASCQTFNFHRRKVEKFFLGNIQLILKGLEVESFYLTTKNLTSNQDYWAEQWNKKINQISAIMEETINSIKGNWHSQLQKDAEEFNVKNYGKGNKEYLEEFYNFLTDKFSWREWFLVVYNPITGGDNHYVSVYGGIINLRSRG-HNIAVASRDKEDNNFNSNLISQVLDNLPR----SFNTKGKGLAESLLMDQLIPAIQRVHKYSLAAVIEWGAGVWF 1220 TES E+ +++EQF ++ K+D++ Q D+VK+ I W +V Y N+ET I ++ + AP + R+++ +F + A KLY++ + +ENL A HRR V F L +LI++G ++E Y + + WN ++ ++ M N IK +HSQ+ D + N NK++ Y FL DKF R WF + Y ++GGD H+VS GG + R+ G N+ VAS DK + F+ + LD+ R S L S + + A + I WG VWF Sbjct: 1548 TESAEMKFLREQFAQVHAKLDSISLQLDDVKRLIEWRTTRVMYANYETFIIAASSILNNYVAAPESSREVLKRQFIAAFQHNPL-APLKLYQAIVEKDFVIAENLAAAVVHYTQNHRRHVINFLLAMQRLIMRGAQLEIAYEKMVHGDGAGNVAKTVWNGRMEKLLIRMMRLENEIKSKYHSQMTSDIGGVILNNRHLSNKDFSGHMYRFLADKFDHRNWFSLAYKDVSGGDKHWVSFCGGDLRFRTHGSRNVVVASADKRSSRFSQPRGNAALDDAQRVGSGSHAESWTNLIRSKIGNSCADA-------AFVGSICWGCDVWF 1864 HSP 2 Score: 140.969 bits (354), Expect = 5.080e-32 Identity = 94/344 (27.33%), Postives = 154/344 (44.77%), Query Frame = 3 Query: 264 ESKELTYMKEQFKIINDKMDTVDQQFDEVKKAINWNVVKVQYFNHETAIGLLQDMILSISDAPSNVRQMMMDRFRITYDQTYYNAADKLYESFTNPQRIFSENLVTASCQTFNFHRRKVEKFFLGNIQLILKGLEVESFYLTTKNLTSNQDYWAEQWNKKINQISAIMEETINSIKGNWHSQLQKDAEEFNVKNYGKGNKEYLEEFYNFLTDKFSWREWFLVVYNPITGGDNHYVSVYGGIINLRSR-GHNIAVASRDKEDNNFNSNLISQVLDNLPRSFNTKGKGLAESLLMDQLIPAI-QRVHKYSLAAVIEWGAGVWFISNNQFRAYKKYTGPRGRTYNII 1289 ES E+ +M+EQFK ++ K+D++ Q +EVK+ I W +V Y N+E+ I ++ S A + + + R +T + AA KLY++ S+NL A HRR V F L +L+++G ++E Y + W+ ++ ++ M++ N + +HSQ+ D + N NK++ Y FL DKF R W + Y ++GGD H+VS GG R+ G N+ VAS + + F + LD R G G + + I + I WG VWF + Y+K + RG ++ Sbjct: 2296 ESAEMKFMREQFKEVHAKLDSISLQLEEVKRLIEWQTTRVTYANYESFIVATTHLLDSYVGANDAMTREVHKRQFLTAFRKNPIAALKLYQAVVETDLTISDNLGVAVVHYTQNHRRNVMNFLLAMQRLVMRGAQLEIAYEKMVHGDHAATVTQALWDTRMEKMLTRMQQVENGVLSKYHSQMTSDIGRVILDNRHLSNKDFSGHMYRFLADKFDRRYWIALSYKDVSGGDKHWVSYCGGDARFRTHGGRNVVVASSNPGSSRFTRAKGNAALDAAQRV----GSGSHAESWTNLIRSKIGNSCSDAAFVGSICWGCDVWFTMRSDRYVYRKMSN-RGDINTVV 2634
BLAST of MFS domain-containing protein vs. Ensembl Cavefish
Match: rpz6 (uncharacterized LOC103039477 [Source:NCBI gene;Acc:103039477]) HSP 1 Score: 58.151 bits (139), Expect = 6.576e-9 Identity = 59/241 (24.48%), Postives = 103/241 (42.74%), Query Frame = 3 Query: 240 VIMAQFETESKELTYMKEQFKIINDKMDTVDQQFDEVKKAINWNVVKVQYFNHETAIGLLQDMILSISDAPSNVRQMMMDRFRITYDQT-----YYNAADKLYESFTNPQRIFSENLVTASCQTFNFHRRKVEKFFLGNIQLILKGLEVESFYLTTKNLTSNQDYWAE---QWNKKINQISAIMEETINSIKGNWHSQLQKDAEEFNVKNYGKGNKEYLEEFYNFLTDKFSWREWFLVVYN 938 V +A +SKE+ Y+KEQF + +K+D + Q +++ I + QYF+ E I L I +A R++ F + +T Y+ D L S T F +++ + +RR +E F + +L GL L LT +D E +W++KI ++ M+ +I + Q + D + + K ++ +E FL K+ W W + V N Sbjct: 48 VRLALDNVQSKEVVYVKEQFLAVRNKLDVLSNQLEDIDCEIKKGRLDYQYFSVEENIRNQFRKYLDILEAKPQFREVKKRLFLEHFSKTGGEKNLYDLYDALMGSST-----FGGSVLEVVEEYEARNRRVLEDFCVRMKELYCLGL---IALLGHCALTQGEDVEQEKIQEWSEKIQEVETKMKASIEECVAFFAEQAKLDVQRLIQEKEDKSLQDIAQELLTFLVRKYDWVSWSVRVIN 280
BLAST of MFS domain-containing protein vs. Ensembl Cavefish
Match: rpz4 (uncharacterized LOC103039774 [Source:NCBI gene;Acc:103039774]) HSP 1 Score: 54.299 bits (129), Expect = 1.113e-7 Identity = 67/279 (24.01%), Postives = 116/279 (41.58%), Query Frame = 3 Query: 165 DFVKTTQAISKWGLPLLKSIG---------YFSKVIMAQFETESKELTYMKEQFKIINDKMDTVDQQFDEVKKAINWNVVKVQYFNHETAIGLLQDMILSISDAPSNVRQMMMDRFRITYDQTYYNAADK----LYESFTNPQRIFS-ENLVTASCQTFNFHRRKVEKFFLGNIQLILKGLEVESFYLTTKNLTSNQDY---WAEQWNKKINQISAIMEETINSIKGNWHSQLQKDAEEFNVKNYGKGNKEYLEEFYNFLTDKFSWREWFLVVYNPITG 950 D V+T + + G ++ SI V +A ESKE YMKEQF+ + ++++ V ++ + + + + YF+ E + + I +A R++ F + +T DK LY + T FS E+++ S RR VE F QL GL + K + WA++ + +++A++E+ INS + SQ + D + N K N++ L K+ W W + V+N TG Sbjct: 14 DVVETVMEVFEQGAEVVASIAGDLFPVFAIAAPIVKLALDNVESKEAEYMKEQFQRVRERLEVVSEEIQRINEEVKKSGADAAYFSVEENLTNQFRKYMDILNAKPKFREVKKKLFLEHFSKT---GGDKNLNILYNAVTGDN--FSGESVLEISLNYEQKSRRAVEDFCARLKQLFCVGLIALMGHAALKGGEDEEGLLKDWADKMKEVQLKMNAVIEDCINS----FPSQAEIDIKRLVRDNRDKPNQQLANMILEALKKKYDWIGWSIRVFNSPTG 283
BLAST of MFS domain-containing protein vs. Ensembl Cavefish
Match: rpz5 (rapunzel 5 [Source:ZFIN;Acc:ZDB-GENE-030131-4678]) HSP 1 Score: 50.8322 bits (120), Expect = 1.546e-6 Identity = 48/248 (19.35%), Postives = 104/248 (41.94%), Query Frame = 3 Query: 207 PLLKSIGYFSKVIMAQFETESKELTYMKEQFKIINDKMDTVDQQFDEVKKAINWNVVKVQYFNHETAI----GLLQDMILSISDAPSNVRQMMMDRFRITYDQTYYNAADKLYESFTNPQRIFSENLVTASCQTFNFHRRKVEKFFLGNIQLILKGLEVESFYLTTKNLTSNQDYWAEQWNKKINQISAIMEETINSIKGNWHSQLQKDAEEFNVKNYGKGNKEYLEEFYNFLTDKFSWREWFLVVYN 938 P+L+++ S I++ E KE Y+ EQF+ +N K++ + + +++ + + Q F+ E + QD +L+ ++ + F T +A LY + T + + ++ T RR VE+F +L L G+ + K+ + + ++W ++ + M+ ++ N+ Q + D E V+ + ++ + L K+ W W + V+N Sbjct: 66 PILEAVFVASAEILSN--PEGKEAKYLAEQFERVNQKLEGIQDEIEKIALELQRTSMNKQNFDREAQMISQYEKFQDFVLAKPKFKEKKKEKFISHFENTDGDLNIDA---LYNAVTG-ENTSGDAMLDTVVTTEQRSRRAVEEFCAQLKKLFLVGIIAVMGHAALKD-GAVGEMMVKKWQDRMEDVERRMKAAVDECINNFPEQAKMDVEHQLVEKPASVDPDFAKNLLEALVKKYDWVSWSIRVFN 306
BLAST of MFS domain-containing protein vs. Ensembl Medaka
Match: rpz4 (uncharacterized LOC101175680 [Source:NCBI gene;Acc:101175680]) HSP 1 Score: 51.2174 bits (121), Expect = 1.233e-6 Identity = 54/239 (22.59%), Postives = 96/239 (40.17%), Query Frame = 3 Query: 240 VIMAQFETESKELTYMKEQFKIINDKMDTVDQQFDEVKKAINWNVVKVQYFNHETAIGLLQDMILSISDAPSNVRQMMMDRFRITYDQTYYNAADKLYESFTNPQRIFSENLVTASCQTFNFHRRKVEKF-------FLGNIQLILKGLEVESFYLTTKNLTSNQDYWAEQWNKKINQISAIMEETINSIKGNWHSQLQKDAEEFNVKNYGKGNKEYLEEFYNFLTDKFSWREWFLVVY 935 V +A ES E +MK+QF+ + D++D V ++ + + I + + ++F+ E I + I +A ++ F + ++ N S F E L+ RR +E++ F I +L V+ F + L WAE+ +I+A++EE I S + +Q + D E G NK+ + L K+ W W + VY Sbjct: 115 VQLALDNVESSEAAFMKDQFQKVRDRLDVVSEEIQRINEEIKKSRIDTEFFSVEENIRNQFRKYMEILNAKPQFTEVKKQNFLKHFSKSGGNKNLHSLYSVVVGDGFFGEPLLVTILNYEEKSRRPIEEYCARLKNLFCIGIIALLGHAAVDGFNEGEELLKE----WAEKMTNVQEKINAVVEECIVS----FPNQAKTDCERLVRDQEGLDNKQLADALIGILKKKYDWVGWSVRVY 345
BLAST of MFS domain-containing protein vs. Planmine SMEST
Match: SMESG000062792.1 (SMESG000062792.1) HSP 1 Score: 815.839 bits (2106), Expect = 0.000e+0 Identity = 424/426 (99.53%), Postives = 426/426 (100.00%), Query Frame = 3 Query: 21 MKFXXXXXXXXXXXXXPIYGLDTSPGXXXXXXXXXXXXXXXFNSIKESDFVKTTQAISKWGLPLLKSIGYFSKVIMAQFETESKELTYMKEQFKIINDKMDTVDQQFDEVKKAINWNVVKVQYFNHETAIGLLQDMILSISDAPSNVRQMMMDRFRITYDQTYYNAADKLYESFTNPQRIFSENLVTASCQTFNFHRRKVEKFFLGNIQLILKGLEVESFYLTTKNLTSNQDYWAEQWNKKINQISAIMEETINSIKGNWHSQLQKDAEEFNVKNYGKGNKEYLEEFYNFLTDKFSWREWFLVVYNPITGGDNHYVSVYGGIINLRSRGHNIAVASRDKEDNNFNSNLISQVLDNLPRSFNTKGKGLAESLLMDQLIPAIQRVHKYSLAAVIEWGAGVWFISNNQFRAYKKYTGPRGRTYNIIVMG 1298 MKFCCYILCLCLSSLIPIYGLDTSPGKILEEASKLEKAKEIFNSIKESDFVKTTQAISKWGLPLLKSIGYFSKVIMAQFETESKELTYMKEQFKIINDKMDTVDQQFDEVKKAINWNVVKVQYFNHETAIGLLQDMILSISDAPSNVRQMMMDRFRITYDQTYYNAADKLYESFTNPQRIFSENLVTASCQTFNFHRRKVEKFFLGNIQLILKGLEVESFYLTTKNLTSNQDYWAEQWNKKINQISAIMEETINSIKGNWHSQLQKDAEEFNVKNYGKGNKEYLEEFYNFLTDKFSWREWFLVVYNPITGGDNHYVSVYGGIINLRSRGHNIAVASRDKEDNNFN+NLISQVLDNLPRSFNT+GKGLAESLLMDQLIPAIQRVHKYSLAAVIEWGAGVWFISNNQFRAYKKYTGPRGRTYNIIVMG Sbjct: 1 MKFCCYILCLCLSSLIPIYGLDTSPGKILEEASKLEKAKEIFNSIKESDFVKTTQAISKWGLPLLKSIGYFSKVIMAQFETESKELTYMKEQFKIINDKMDTVDQQFDEVKKAINWNVVKVQYFNHETAIGLLQDMILSISDAPSNVRQMMMDRFRITYDQTYYNAADKLYESFTNPQRIFSENLVTASCQTFNFHRRKVEKFFLGNIQLILKGLEVESFYLTTKNLTSNQDYWAEQWNKKINQISAIMEETINSIKGNWHSQLQKDAEEFNVKNYGKGNKEYLEEFYNFLTDKFSWREWFLVVYNPITGGDNHYVSVYGGIINLRSRGHNIAVASRDKEDNNFNANLISQVLDNLPRSFNTRGKGLAESLLMDQLIPAIQRVHKYSLAAVIEWGAGVWFISNNQFRAYKKYTGPRGRTYNIIVMG 426
BLAST of MFS domain-containing protein vs. Planmine SMEST
Match: SMESG000004912.1 (SMESG000004912.1) HSP 1 Score: 327.02 bits (837), Expect = 2.889e-108 Identity = 155/340 (45.59%), Postives = 232/340 (68.24%), Query Frame = 3 Query: 144 FNSIKESDFVKTTQAISKWGLPLLKSIGYFSKVIMAQFETESKELTYMKEQFKIINDKMDTVDQQFDEVKKAINWNVVKVQYFNHETAIGLLQDMILSISDAPSNVRQMMMDRFRITYDQTYYNAADKLYESFTNPQRIFSENLVTASCQTFNFHRRKVEKFFLGNIQLILKGLEVESFYLTTKNLTSNQDYWAEQWNKKINQISAIMEETINSIKGNWHSQLQKDAEEFNVKNYGKGNKEYLEEFYNFLTDKFSWREWFLVVYNPITGGDNHYVSVYGGIINLRSRGHNIAVASRDKEDNNFNSNLISQVLDNLPRSFNTKGKGLAESLLMDQLIPAIQ 1163 F++IKESD KT +AI+KWG PLL++IG F+K+IM QFE++SKELT+MKEQFKI+N+KMD VDQQF+EVK+ ++WNVVK+QY +E + +LQ +I I+D+P+++R + +D+F ++YDQ Y NAA+ LY+ F N ++FSENLV A + HR ++EKFF+GNIQLI+K LEVE+FY+ KN TS + +W +W+ ++N + IM+ I NW +Q D EEFN +N K ++ Y ++ YNFL DKF R W ++VY+P+ G +H + GI ++ GHN+AV+S N N + + +P++ + G G A +L+ L P ++ Sbjct: 46 FDNIKESDMYKTGKAIAKWGKPLLEAIGSFAKIIMVQFESDSKELTFMKEQFKILNEKMDYVDQQFEEVKRLMDWNVVKIQYGKYEMHVYMLQHLIQIIADSPASLRHITIDKFLLSYDQVYDNAAENLYQGFINQNKVFSENLVLAIRKYTKDHRYQIEKFFMGNIQLIIKCLEVETFYINLKNFTSIEKFWQVKWSDRMNSLMDIMKTVSEKISENWEAQSNMDIEEFNAENGKKSHENYAKDLYNFLNDKFRNRIWLVLVYDPLDSGTDHALKACNGISQMQRNGHNVAVSSLPFGTRALNKNYYASICSRIPQNIGSWGHGPAHFVLLHYLQPKME 385
BLAST of MFS domain-containing protein vs. Planmine SMEST
Match: SMESG000052592.1 (SMESG000052592.1) HSP 1 Score: 156.377 bits (394), Expect = 9.796e-43 Identity = 102/378 (26.98%), Postives = 189/378 (50.00%), Query Frame = 3 Query: 144 FNSIKESDFVKTTQAISKWGLPLLKSIGYFSKVIMAQFETESKELTYMKEQFKIINDKMDTVDQQFDEVKKAINWNVVKVQYFNHETAIGLLQDMILSISDAPSNVRQMMMDRFRITYDQTYYNAADKLYESFTNPQRIFSENLVTASCQTFNFHRRKVEKFFLGNIQLILKGLEVESFYLTTK-NLTSNQDYWAEQWNKKINQISAIMEETINSIKGNWHSQLQKDAEEFNVKNYGKGNKEYLEEFYNFLTDKFSWREWFLVVYNPITGGDNHYVSVYGGIINLRSRGHNIAVASRDKEDNNFNSNLIS---QVLDNLPRSFNTKGKGLAESL----LMDQLIPAIQRVHKYSLAAVIEWGAGVWFISNNQFRAYKK 1253 F ++E +F KT IS P+ +I V+ E ES E+ MK++F +N+++D +F +K+ I+W+ V++ + + E I L M+ ++ + P R+ F TY+ Y A D L+ + N ++I+S NL+ A+ R +V++F +G ++LI + +++E+ Y+ K N + W KK+ + +E+ K ++ Q QKD + +Y + N+ ++ Y+F K++WREWF++VY ++G +H V G R+ G NI V+S D+ + + I+ Q++ N +N++ +G S +++P A + WG+ VWFI N + Y+K Sbjct: 59 FKFLEEKNFFKTLTQISSVAGPIFSAISAILTVVFMFIEIESPEMALMKKEFANLNNRIDKWGVEFQIIKRKIDWSAVQINFADIENNIITLHKMLSTLPEVPIANRETQAALFINTYEINYKAAGDILHRAMLNIEQIYSVNLLRAAQLYMENDRNQVQEFMVGMMKLITQAVQIEAAYVGLKYNNEEASKFTQSLWEKKLAVLKDKLEQIDTDTKNKYNEQYQKDLDNLLATHYSQSNERFVTIAYDFFATKYNWREWFVLVYKELSGFKDHAVVTCQGTHRFRTHGRNIIVSSVDQSEGDAAMAHINRNKQIIGN----YNSQWQGGEHSKHWVEYWGRVLPLCSDA---DTRASVAWGSNVWFI-NTRLVVYQK 428
BLAST of MFS domain-containing protein vs. Planmine SMEST
Match: SMESG000052591.1 (SMESG000052591.1) HSP 1 Score: 129.798 bits (325), Expect = 3.970e-33 Identity = 87/311 (27.97%), Postives = 150/311 (48.23%), Query Frame = 3 Query: 333 QQFDEVKKAINWNVVKVQYFNHETAIGLLQDMILSISDAPSNVRQMMMDRFRITYDQTYYNAADKLYESFTNPQRIFSENLVTASCQTFNFHRRKVEKFFLGNIQLILKGLEVESFYLTTK-NLTSNQDYWAEQWNKKINQISAIMEETINSIKGNWHSQLQKDAEEFNVKNYGKGNKEYLEEFYNFLTDKFSWREWFLVVYNPITGGDNHYVSVYGGIINLRSRGHNIAVASRDKEDNNFNSNLIS---QVLDNLPRSFNTKGKGLAESLLMDQLIPAIQRVHKYSLAAVIEWGAGVWFISNNQFRAYKK 1253 + F+EV+ +I+W VV++ + + E I +Q + N ++ +F +Y+ Y D LY N + FS NL AS + F R+KV+ F + +L+++ + +E+ + K N + W ++ + A ME K + +Q Q D +E+ + N+++ + YN+L+ K++WR+WF+VVY PI+G +H VS G R+ G NI V+S DKED + I Q++ + + K MD+L+P + + WG+ VWF +N YKK Sbjct: 100 EDFNEVRYSIDWAVVQINFEDLENRILTVQRLSTEFMSIDDNEKEFSAKQFLHSYEANYKATGDLLYSVMININQSFSGNLFRASQKFTQFDRKKVQTFMVELAKLLVQAVNIEANFANLKYENDENVKFLNSMWRERFKTLKATMEAVDLDTKEQFRNQYQMDLDEYLMTRESLTNEQFNQVLYNYLSTKYNWRDWFVVVYAPISGFKDHTVSTCQGTYRFRTNGRNIIVSSVDKEDGISAGSHIERNKQIIGSYSDWKSDKEYSRGWVSFMDKLLP---NCNDADTRLSVAWGSNVWF-TNTNLVVYKK 406
BLAST of MFS domain-containing protein vs. Planmine SMEST
Match: SMESG000027656.1 (SMESG000027656.1) HSP 1 Score: 84.7297 bits (208), Expect = 1.522e-17 Identity = 75/320 (23.44%), Postives = 134/320 (41.88%), Query Frame = 3 Query: 168 FVKTTQAISKWGLPLLKSIGYFSKVIMAQFETESKELTYMKEQFKIINDKMDTVDQQFDEVKKAINWNVVKVQYFNHETAIGLLQDMILSISDAPSNVRQMMMDRFRITYDQTYYNAADKLYESFTNPQRIFSENLVTASCQTFNFHRRKVEKFFLGNIQLILKGLEVESFYLTTKNLTSNQDYWAEQWNKKINQISAIMEETINSIKGNWHSQLQKDAEEFNVKNYGKGNKEYLEEFYNFLTDKFSWREWFLVVYNPITGGDNHYVSVYGGIINL-RSRGHNIAVASRDKEDNNFNSNLISQVLDNLPRSFNTKGKGLA 1124 F K + + G + S V M + +S EL +KE F+ +N+K+DT+ + ++ I + + Y T+I + ++++A + + D F Y+ ++ A +Y++ T F N+V + K+ +F +QLI KGL VE YL N ++ E W KIN++S I + + NW + +E + + G N+ + E L + R W + YN +G H S Y + + R H+ +V S K + L DN + N + + +A Sbjct: 59 FAKLSGVLGSLGPAAMAISAILSIVTMFLPKEDSPELKAIKEGFEKVNNKLDTISSKIGSLENIIELSSARAAYVKTVTSI---NNNYETLNEAKKSNSKEGYDYFAKQYENSFEFATANMYDAMTGSTGPFGFNMVNLYKTHVRCNPVKLSQFCTMGLQLITKGLTVEGAYLGYMNFSAKAKGKTETWTTKINEVSKQCSAVIEACESNWKEFAYQQYKETHRELEGD-NQAFAERLAKDLENVAPQRSWLTIAYNDASGFGPHTYSTYYEVHTIWNERNHDTSVFSVPK-----SPKLTGSDYDNFVKLINGQKEAIA 369 The following BLAST results are available for this feature:
BLAST of MFS domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 0
BLAST of MFS domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of MFS domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of MFS domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 3
BLAST of MFS domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 0
BLAST of MFS domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 0
BLAST of MFS domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 0
BLAST of MFS domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of MFS domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 3
BLAST of MFS domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of MFS domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of MFS domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 0
BLAST of MFS domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 1
BLAST of MFS domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30020480 ID=SMED30020480|Name=MFS domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1325bpback to top protein sequence of SMED30020480-orf-1 >SMED30020480-orf-1 ID=SMED30020480-orf-1|Name=SMED30020480-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=427bp MKFCCYILCLCLSSLIPIYGLDTSPGKILEEASKLEKAKEIFNSIKESDFback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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