negative regulator of reactive oxygen species-like

Overview


Name	negative regulator of reactive oxygen species-like
Smed ID	SMED30020478
Length (bp)	1711

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of negative regulator of reactive oxygen species-like (SMED30020478) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for negative regulator of reactive oxygen species-like (SMED30020478) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30020478

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
nervous system	SMED30020478	h1SMcG0011910	dd_Smed_v4_9875_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30020478	h1SMcG0011910	dd_Smed_v4_9875_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30020478	h1SMcG0011910	dd_Smed_v4_9875_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30020478	h1SMcG0011910	dd_Smed_v4_9875_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Fly
Match: Pxn (gene:FBgn0011828 transcript:FBtr0072950)

HSP 1 Score: 52.7582 bits (125), Expect = 5.298e-7
Identity = 48/219 (21.92%), Postives = 88/219 (40.18%), Query Frame = 2

Query:  893 KFPKLEELALSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDYMLRYKFGKVYLQGNIFNCNCEM--IWIRSIEADRIKGLKCDNVNFEKHVKNQELTRSRILKSKMICTEP-LLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWIKNQQTLKIENPPLDRLNNKTVMKNLIIPDDIKTADNETYVCRAKSIAG 1540
            + P+LE + L +N I Q+P+ +   LP L  L + NNKLT LP   +       ++ L GN  +CNC +  +W R                   H+  Q     +++   + C  P +L+ Q       + +  +     +      +     +   C   G P P++ W+ N Q L +E    ++   + +    ++     T+D   Y C A++  G
Sbjct:  122 RMPRLEAIFLENNDIWQLPAGLFDNLPRLNRLIMYNNKLTQLPVDGFNRLNNLKRLRLDGNAIDCNCGVYSLWRR------------------WHLDVQR----QLVSISLTCAAPQMLQNQGFSSLGEHHFKCAKPQFLVAPQDAQVAAGEQVELSCEVTGLPRPQITWMHNTQELGLE----EQAQAEILPSGSLLIRSADTSDMGIYQCIARNEMG 314

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Fly
Match: Pxn (gene:FBgn0011828 transcript:FBtr0072954)

HSP 1 Score: 51.9878 bits (123), Expect = 1.674e-6
Identity = 48/219 (21.92%), Postives = 88/219 (40.18%), Query Frame = 2

Query:  893 KFPKLEELALSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDYMLRYKFGKVYLQGNIFNCNCEM--IWIRSIEADRIKGLKCDNVNFEKHVKNQELTRSRILKSKMICTEP-LLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWIKNQQTLKIENPPLDRLNNKTVMKNLIIPDDIKTADNETYVCRAKSIAG 1540
            + P+LE + L +N I Q+P+ +   LP L  L + NNKLT LP   +       ++ L GN  +CNC +  +W R                   H+  Q     +++   + C  P +L+ Q       + +  +     +      +     +   C   G P P++ W+ N Q L +E    ++   + +    ++     T+D   Y C A++  G
Sbjct:  122 RMPRLEAIFLENNDIWQLPAGLFDNLPRLNRLIMYNNKLTQLPVDGFNRLNNLKRLRLDGNAIDCNCGVYSLWRRW------------------HLDVQR----QLVSISLTCAAPQMLQNQGFSSLGEHHFKCAKPQFLVAPQDAQVAAGEQVELSCEVTGLPRPQITWMHNTQELGLE----EQAQAEILPSGSLLIRSADTSDMGIYQCIARNEMG 314

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Fly
Match: Pxn (gene:FBgn0011828 transcript:FBtr0072951)

HSP 1 Score: 51.9878 bits (123), Expect = 1.674e-6
Identity = 48/219 (21.92%), Postives = 88/219 (40.18%), Query Frame = 2

Query:  893 KFPKLEELALSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDYMLRYKFGKVYLQGNIFNCNCEM--IWIRSIEADRIKGLKCDNVNFEKHVKNQELTRSRILKSKMICTEP-LLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWIKNQQTLKIENPPLDRLNNKTVMKNLIIPDDIKTADNETYVCRAKSIAG 1540
            + P+LE + L +N I Q+P+ +   LP L  L + NNKLT LP   +       ++ L GN  +CNC +  +W R                   H+  Q     +++   + C  P +L+ Q       + +  +     +      +     +   C   G P P++ W+ N Q L +E    ++   + +    ++     T+D   Y C A++  G
Sbjct:  122 RMPRLEAIFLENNDIWQLPAGLFDNLPRLNRLIMYNNKLTQLPVDGFNRLNNLKRLRLDGNAIDCNCGVYSLWRRW------------------HLDVQR----QLVSISLTCAAPQMLQNQGFSSLGEHHFKCAKPQFLVAPQDAQVAAGEQVELSCEVTGLPRPQITWMHNTQELGLE----EQAQAEILPSGSLLIRSADTSDMGIYQCIARNEMG 314

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Fly
Match: Pxn (gene:FBgn0011828 transcript:FBtr0072952)

HSP 1 Score: 51.9878 bits (123), Expect = 1.674e-6
Identity = 48/219 (21.92%), Postives = 88/219 (40.18%), Query Frame = 2

Query:  893 KFPKLEELALSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDYMLRYKFGKVYLQGNIFNCNCEM--IWIRSIEADRIKGLKCDNVNFEKHVKNQELTRSRILKSKMICTEP-LLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWIKNQQTLKIENPPLDRLNNKTVMKNLIIPDDIKTADNETYVCRAKSIAG 1540
            + P+LE + L +N I Q+P+ +   LP L  L + NNKLT LP   +       ++ L GN  +CNC +  +W R                   H+  Q     +++   + C  P +L+ Q       + +  +     +      +     +   C   G P P++ W+ N Q L +E    ++   + +    ++     T+D   Y C A++  G
Sbjct:  122 RMPRLEAIFLENNDIWQLPAGLFDNLPRLNRLIMYNNKLTQLPVDGFNRLNNLKRLRLDGNAIDCNCGVYSLWRRW------------------HLDVQR----QLVSISLTCAAPQMLQNQGFSSLGEHHFKCAKPQFLVAPQDAQVAAGEQVELSCEVTGLPRPQITWMHNTQELGLE----EQAQAEILPSGSLLIRSADTSDMGIYQCIARNEMG 314

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Fly
Match: Pxn (gene:FBgn0011828 transcript:FBtr0072953)

HSP 1 Score: 51.9878 bits (123), Expect = 1.674e-6
Identity = 48/219 (21.92%), Postives = 88/219 (40.18%), Query Frame = 2

Query:  893 KFPKLEELALSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDYMLRYKFGKVYLQGNIFNCNCEM--IWIRSIEADRIKGLKCDNVNFEKHVKNQELTRSRILKSKMICTEP-LLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWIKNQQTLKIENPPLDRLNNKTVMKNLIIPDDIKTADNETYVCRAKSIAG 1540
            + P+LE + L +N I Q+P+ +   LP L  L + NNKLT LP   +       ++ L GN  +CNC +  +W R                   H+  Q     +++   + C  P +L+ Q       + +  +     +      +     +   C   G P P++ W+ N Q L +E    ++   + +    ++     T+D   Y C A++  G
Sbjct:  122 RMPRLEAIFLENNDIWQLPAGLFDNLPRLNRLIMYNNKLTQLPVDGFNRLNNLKRLRLDGNAIDCNCGVYSLWRRW------------------HLDVQR----QLVSISLTCAAPQMLQNQGFSSLGEHHFKCAKPQFLVAPQDAQVAAGEQVELSCEVTGLPRPQITWMHNTQELGLE----EQAQAEILPSGSLLIRSADTSDMGIYQCIARNEMG 314

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Zebrafish
Match: pxdn (peroxidasin [Source:ZFIN;Acc:ZDB-GENE-140415-2])

HSP 1 Score: 69.707 bits (169), Expect = 7.093e-12
Identity = 56/231 (24.24%), Postives = 103/231 (44.59%), Query Frame = 2

Query:  905 LEELALSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDYMLRYKFGKVYLQGNIFNCNCEMIWIRSIEADRIKGLKCDNVNFEKHVKNQELTRSRILKSKMICTEP-LLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWIKNQQTLKI-ENPPLDRLNNKTVMKNLIIPDDIKTADNETYVCRAKSIAGISEIRL-EVTKKYSKNP 1588
            LE+L L  N I  +       LP L+ L + NN+++ L    +       ++ L  N  +C+CE++W+    AD +K                +   S   ++   C  P  L+ +      +++    V   T +    D+   + + + C  EGNP P++ W++N   L + ++  L+ L + T+M       D +  D   Y C AK++AG  E++  EVT +Y ++P
Sbjct:  126 LEQLYLHFNNIESLEPESFSHLPKLERLFLHNNRISHLALGTFSHLQSMKRLRLDSNALHCDCELLWL----ADLLK----------------QYAESGNAQAAATCDYPNRLQGRSVATLTAHELNCEVPRITSEPQDVDVTSGNTVYFTCRAEGNPKPQIIWLRNNNALNMRDDTRLNLLEDGTLMIQ-----DTRETDQGVYQCMAKNVAG--EVKTSEVTLRYFRSP 329

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Zebrafish
Match: pxdn (peroxidasin [Source:ZFIN;Acc:ZDB-GENE-140415-2])

HSP 1 Score: 69.3218 bits (168), Expect = 1.005e-11
Identity = 56/231 (24.24%), Postives = 103/231 (44.59%), Query Frame = 2

Query:  905 LEELALSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDYMLRYKFGKVYLQGNIFNCNCEMIWIRSIEADRIKGLKCDNVNFEKHVKNQELTRSRILKSKMICTEP-LLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWIKNQQTLKI-ENPPLDRLNNKTVMKNLIIPDDIKTADNETYVCRAKSIAGISEIRL-EVTKKYSKNP 1588
            LE+L L  N I  +       LP L+ L + NN+++ L    +       ++ L  N  +C+CE++W+    AD +K                +   S   ++   C  P  L+ +      +++    V   T +    D+   + + + C  EGNP P++ W++N   L + ++  L+ L + T+M       D +  D   Y C AK++AG  E++  EVT +Y ++P
Sbjct:   96 LEQLYLHFNNIESLEPESFSHLPKLERLFLHNNRISHLALGTFSHLQSMKRLRLDSNALHCDCELLWL----ADLLK----------------QYAESGNAQAAATCDYPNRLQGRSVATLTAHELNCEVPRITSEPQDVDVTSGNTVYFTCRAEGNPKPQIIWLRNNNALNMRDDTRLNLLEDGTLMIQ-----DTRETDQGVYQCMAKNVAG--EVKTSEVTLRYFRSP 299

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Zebrafish
Match: pxdn (peroxidasin [Source:ZFIN;Acc:ZDB-GENE-140415-2])

HSP 1 Score: 68.9366 bits (167), Expect = 1.103e-11
Identity = 56/231 (24.24%), Postives = 103/231 (44.59%), Query Frame = 2

Query:  905 LEELALSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDYMLRYKFGKVYLQGNIFNCNCEMIWIRSIEADRIKGLKCDNVNFEKHVKNQELTRSRILKSKMICTEP-LLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWIKNQQTLKI-ENPPLDRLNNKTVMKNLIIPDDIKTADNETYVCRAKSIAGISEIRL-EVTKKYSKNP 1588
            LE+L L  N I  +       LP L+ L + NN+++ L    +       ++ L  N  +C+CE++W+    AD +K                +   S   ++   C  P  L+ +      +++    V   T +    D+   + + + C  EGNP P++ W++N   L + ++  L+ L + T+M       D +  D   Y C AK++AG  E++  EVT +Y ++P
Sbjct:  128 LEQLYLHFNNIESLEPESFSHLPKLERLFLHNNRISHLALGTFSHLQSMKRLRLDSNALHCDCELLWL----ADLLK----------------QYAESGNAQAAATCDYPNRLQGRSVATLTAHELNCEVPRITSEPQDVDVTSGNTVYFTCRAEGNPKPQIIWLRNNNALNMRDDTRLNLLEDGTLMIQ-----DTRETDQGVYQCMAKNVAG--EVKTSEVTLRYFRSP 331

[Close]

Query:  905 LEELALSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDYMLRYKFGKVYLQGNIFNCNCEMIWIRSIEADRIKGLKCDNVNFEKHVKNQELTRSRILKSKMICTEP-LLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWIKNQQTLKI-ENPPLDRLNNKTVMKNLIIPDDIKTADNETYVCRAKSIAGISEIRL-EVTKKYSKNP 1588
            LE+L L  N I  +       LP L+ L + NN+++ L    +       ++ L  N  +C+CE++W+    AD +K                +   S   ++   C  P  L+ +      +++    V   T +    D+   + + + C  EGNP P++ W++N   L + ++  L+ L + T+M       D +  D   Y C AK++AG  E++  EVT +Y ++P
Sbjct:  131 LEQLYLHFNNIESLEPESFSHLPKLERLFLHNNRISHLALGTFSHLQSMKRLRLDSNALHCDCELLWL----ADLLK----------------QYAESGNAQAAATCDYPNRLQGRSVATLTAHELNCEVPRITSEPQDVDVTSGNTVYFTCRAEGNPKPQIIWLRNNNALNMRDDTRLNLLEDGTLMIQ-----DTRETDQGVYQCMAKNVAG--EVKTSEVTLRYFRSP 334

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Zebrafish
Match: pxdn (peroxidasin [Source:ZFIN;Acc:ZDB-GENE-140415-2])

HSP 1 Score: 64.6994 bits (156), Expect = 7.808e-11
Identity = 58/241 (24.07%), Postives = 104/241 (43.15%), Query Frame = 2

Query:  884 PDMKFPKLEELA---LSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDYMLRYKFGKVYLQGNIFNCNCEMIWIRSIEADRIKGLKCDNVNFEKHVKNQELTRSRILKSKMICTEP-LLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWIKNQQTLKI-ENPPLDRLNNKTVMKNLIIPDDIKTADNETYVCRAKSIAGISEIRL-EVTKKYSKNP 1588
            P   F  LE L    L  N I  +       LP L+ L + NN+++ L    +       ++ L  N  +C+CE++W+    AD +K                +   S   ++   C  P  L+ +      +++    V   T +    D+   + + + C  EGNP P++ W++N   L + ++  L+ L + T+M       D +  D   Y C AK++AG  E++  EVT +Y ++P
Sbjct:   97 PRGAFEDLENLKYLYLHFNNIESLEPESFSHLPKLERLFLHNNRISHLALGTFSHLQSMKRLRLDSNALHCDCELLWL----ADLLK----------------QYAESGNAQAAATCDYPNRLQGRSVATLTAHELNCEVPRITSEPQDVDVTSGNTVYFTCRAEGNPKPQIIWLRNNNALNMRDDTRLNLLEDGTLMI-----QDTRETDQGVYQCMAKNVAG--EVKTSEVTLRYFRSP 310

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Xenopus
Match: polr1e (polymerase (RNA) I polypeptide E [Source:Xenbase;Acc:XB-GENE-1003651])

HSP 1 Score: 67.781 bits (164), Expect = 3.510e-11
Identity = 59/245 (24.08%), Postives = 105/245 (42.86%), Query Frame = 2

Query:  902 KLEELALSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDYMLRYKFGKVYLQGNIFNCNCEMIWIRS---IEADRIKGLKCDNVNFEKHVKNQELTRSRILKSKMICTEPLLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWIKNQQTLKI-ENPPLDRLNNKTVMKNLIIPDDIKTADNETYVCRAKSIAGISEIRL-EVTKKYSKNPMPALGQIDLQN 1621
             LE+L L  N I  +      +LP L+ L + NN++T L    +       ++ L  N  +C+CE++W+     I ++           + + ++ + +  S I  S++ C  P +  +  D                     D+   + + + C  EGNP P + W++N   L + ++  L+ LN+ T+M       + K  D   Y C AK++AG  E++  EVT +Y   P      I  QN
Sbjct:  194 SLEQLYLHFNQIETLEPESFNYLPKLERLFLHNNRITHLVPGTFSQLESMKRLRLDSNALHCDCEILWLADLLKIYSESGNAQAAATCEYPRRLQGRSV--STITPSELNCERPRITSEPQD--------------------VDVTFGNTVYFTCRAEGNPKPEIIWLRNNNELSMKDDSRLNLLNDGTLMIQ-----NTKETDQGIYQCMAKNVAG--EVKTHEVTLRYYGTPATPTFVIQPQN 409

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Xenopus
Match: polr1e (polymerase (RNA) I polypeptide E [Source:Xenbase;Acc:XB-GENE-1003651])

HSP 1 Score: 67.781 bits (164), Expect = 3.622e-11
Identity = 59/245 (24.08%), Postives = 105/245 (42.86%), Query Frame = 2

Query:  902 KLEELALSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDYMLRYKFGKVYLQGNIFNCNCEMIWIRS---IEADRIKGLKCDNVNFEKHVKNQELTRSRILKSKMICTEPLLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWIKNQQTLKI-ENPPLDRLNNKTVMKNLIIPDDIKTADNETYVCRAKSIAGISEIRL-EVTKKYSKNPMPALGQIDLQN 1621
             LE+L L  N I  +      +LP L+ L + NN++T L    +       ++ L  N  +C+CE++W+     I ++           + + ++ + +  S I  S++ C  P +  +  D                     D+   + + + C  EGNP P + W++N   L + ++  L+ LN+ T+M       + K  D   Y C AK++AG  E++  EVT +Y   P      I  QN
Sbjct:  133 SLEQLYLHFNQIETLEPESFNYLPKLERLFLHNNRITHLVPGTFSQLESMKRLRLDSNALHCDCEILWLADLLKIYSESGNAQAAATCEYPRRLQGRSV--STITPSELNCERPRITSEPQD--------------------VDVTFGNTVYFTCRAEGNPKPEIIWLRNNNELSMKDDSRLNLLNDGTLMIQ-----NTKETDQGIYQCMAKNVAG--EVKTHEVTLRYYGTPATPTFVIQPQN 348

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Xenopus
Match: polr1e (polymerase (RNA) I polypeptide E [Source:Xenbase;Acc:XB-GENE-1003651])

HSP 1 Score: 67.781 bits (164), Expect = 4.117e-11
Identity = 59/245 (24.08%), Postives = 105/245 (42.86%), Query Frame = 2

Query:  902 KLEELALSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDYMLRYKFGKVYLQGNIFNCNCEMIWIRS---IEADRIKGLKCDNVNFEKHVKNQELTRSRILKSKMICTEPLLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWIKNQQTLKI-ENPPLDRLNNKTVMKNLIIPDDIKTADNETYVCRAKSIAGISEIRL-EVTKKYSKNPMPALGQIDLQN 1621
             LE+L L  N I  +      +LP L+ L + NN++T L    +       ++ L  N  +C+CE++W+     I ++           + + ++ + +  S I  S++ C  P +  +  D                     D+   + + + C  EGNP P + W++N   L + ++  L+ LN+ T+M       + K  D   Y C AK++AG  E++  EVT +Y   P      I  QN
Sbjct:  128 SLEQLYLHFNQIETLEPESFNYLPKLERLFLHNNRITHLVPGTFSQLESMKRLRLDSNALHCDCEILWLADLLKIYSESGNAQAAATCEYPRRLQGRSV--STITPSELNCERPRITSEPQD--------------------VDVTFGNTVYFTCRAEGNPKPEIIWLRNNNELSMKDDSRLNLLNDGTLMIQ-----NTKETDQGIYQCMAKNVAG--EVKTHEVTLRYYGTPATPTFVIQPQN 343

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Xenopus
Match: polr1e (polymerase (RNA) I polypeptide E [Source:Xenbase;Acc:XB-GENE-1003651])

HSP 1 Score: 65.0846 bits (157), Expect = 2.810e-10
Identity = 61/254 (24.02%), Postives = 106/254 (41.73%), Query Frame = 2

Query:  884 PDMKFPKLEELA---LSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDYMLRYKFGKVYLQGNIFNCNCEMIWIRS---IEADRIKGLKCDNVNFEKHVKNQELTRSRILKSKMICTEPLLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWIKNQQTLKI-ENPPLDRLNNKTVMKNLIIPDDIKTADNETYVCRAKSIAGISEIRL-EVTKKYSKNPMPALGQIDLQN 1621
            P   F  LE L    L  N I  +      +LP L+ L + NN++T L    +       ++ L  N  +C+CE++W+     I ++           + + ++ + +  S I  S++ C  P +  +  D                     D+   + + + C  EGNP P + W++N   L + ++  L+ LN+ T+M       + K  D   Y C AK++AG  E++  EVT +Y   P      I  QN
Sbjct:   95 PSEAFKDLENLKYLYLHFNQIETLEPESFNYLPKLERLFLHNNRITHLVPGTFSQLESMKRLRLDSNALHCDCEILWLADLLKIYSESGNAQAAATCEYPRRLQGRSV--STITPSELNCERPRITSEPQD--------------------VDVTFGNTVYFTCRAEGNPKPEIIWLRNNNELSMKDDSRLNLLNDGTLMIQ-----NTKETDQGIYQCMAKNVAG--EVKTHEVTLRYYGTPATPTFVIQPQN 319

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Xenopus
Match: polr1e (polymerase (RNA) I polypeptide E [Source:Xenbase;Acc:XB-GENE-1003651])

HSP 1 Score: 52.7582 bits (125), Expect = 1.665e-6
Identity = 49/202 (24.26%), Postives = 85/202 (42.08%), Query Frame = 2

Query: 1037 LRYKFGKV--YLQGNIFNCNCEMIWIRS---IEADRIKGLKCDNVNFEKHVKNQELTRSRILKSKMICTEPLLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWIKNQQTLKI-ENPPLDRLNNKTVMKNLIIPDDIKTADNETYVCRAKSIAGISEIRL-EVTKKYSKNPMPALGQIDLQN 1621
            LR   G V   L  N  +C+CE++W+     I ++           + + ++ + +  S I  S++ C  P +  +  D                     D+   + + + C  EGNP P + W++N   L + ++  L+ LN+ T+M       + K  D   Y C AK++AG  E++  EVT +Y   P      I  QN
Sbjct:    4 LRTVRGSVNQRLDSNALHCDCEILWLADLLKIYSESGNAQAAATCEYPRRLQGRSV--STITPSELNCERPRITSEPQD--------------------VDVTFGNTVYFTCRAEGNPKPEIIWLRNNNELSMKDDSRLNLLNDGTLMIQ-----NTKETDQGIYQCMAKNVAG--EVKTHEVTLRYYGTPATPTFVIQPQN 176

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Mouse
Match: Ntrk3 (neurotrophic tyrosine kinase, receptor, type 3 [Source:MGI Symbol;Acc:MGI:97385])

HSP 1 Score: 50.0618 bits (118), Expect = 6.500e-6
Identity = 55/239 (23.01%), Postives = 108/239 (45.19%), Query Frame = 2

Query:  887 DMK-FPKLEELALSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDYMLRYKFGKVYLQGNIFNCNCEMIWIRSIEADRIKGLKCDNVNFEKHVKNQELTRSRILKSKMICTE------PLLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWI-KNQQTLKIENPPLDRLNNKTVMKNLIIPDDIKTADNE-TYVCRAKSIAGISEIRLEVTKKY 1576
            DM+ +  L++L + ++G+  I        P+L+ +++ +N+LTTL S          ++ L+ N FNC+C++ W++                       QE   +R+    + C        PL ++ +S Q    + ++S V+  L + + D   N +I+  C G G+P P + WI    Q++      L+  N   +   L+   ++ + DN  T  C A+++ G+S   + +T  Y
Sbjct:   98 DMELYTGLQKLTIKNSGLRNIQPRAFAKNPHLRYINLSSNRLTTL-SWQLFQTLSLRELRLEQNFFNCSCDIRWMQLW---------------------QEQGEARLDSQSLYCISADGSQLPLFRMNIS-QCDLPEISVSHVN--LTVREGD---NAVIT--CNGSGSPLPDVDWIVTGLQSINTHQTNLNWTNVHAINLTLV---NVTSEDNGFTLTCIAENVVGMSNASVALTVYY 303

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Mouse
Match: Ntrk3 (neurotrophic tyrosine kinase, receptor, type 3 [Source:MGI Symbol;Acc:MGI:97385])

HSP 1 Score: 49.6766 bits (117), Expect = 9.654e-6
Identity = 55/239 (23.01%), Postives = 105/239 (43.93%), Query Frame = 2

Query:  887 DMK-FPKLEELALSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDYMLRYKFGKVYLQGNIFNCNCEMIWIRSIEADRIKGLKCDNVNFEKHVKNQELTRSRILKSKMICTE------PLLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWI-KNQQTLKIENPPLDRLNNKTVMKNLIIPDDIKTADNE-TYVCRAKSIAGISEIRLEVTKKY 1576
            DM+ +  L++L + ++G+  I        P+L+ +++ +N+LTTL S          ++ L+ N FNC+C++ W++                       QE   +R+    + C        PL ++ +S   +     ISV    L + + D   N +I+  C G G+P P + WI    Q++      L+  N   +   L+   ++ + DN  T  C A+++ G+S   + +T  Y
Sbjct:   98 DMELYTGLQKLTIKNSGLRNIQPRAFAKNPHLRYINLSSNRLTTL-SWQLFQTLSLRELRLEQNFFNCSCDIRWMQLW---------------------QEQGEARLDSQSLYCISADGSQLPLFRMNIS---QCDLPEISVSHVNLTVREGD---NAVIT--CNGSGSPLPDVDWIVTGLQSINTHQTNLNWTNVHAINLTLV---NVTSEDNGFTLTCIAENVVGMSNASVALTVYY 303

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. UniProt/SwissProt
Match: sp|A4IGL7|PXDN_XENTR (Peroxidasin OS=Xenopus tropicalis OX=8364 GN=pxdn PE=2 SV=1)

HSP 1 Score: 67.781 bits (164), Expect = 2.125e-10
Identity = 59/245 (24.08%), Postives = 105/245 (42.86%), Query Frame = 2

Query:  902 KLEELALSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDYMLRYKFGKVYLQGNIFNCNCEMIWIRS---IEADRIKGLKCDNVNFEKHVKNQELTRSRILKSKMICTEPLLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWIKNQQTLKI-ENPPLDRLNNKTVMKNLIIPDDIKTADNETYVCRAKSIAGISEIRL-EVTKKYSKNPMPALGQIDLQN 1621
             LE+L L  N I  +      +LP L+ L + NN++T L    +       ++ L  N  +C+CE++W+     I ++           + + ++ + +  S I  S++ C  P +  +  D                     D+   + + + C  EGNP P + W++N   L + ++  L+ LN+ T+M       + K  D   Y C AK++AG  E++  EVT +Y   P      I  QN
Sbjct:  125 SLEQLYLHFNQIETLEPESFNYLPKLERLFLHNNRITHLVPGTFSQLESMKRLRLDSNALHCDCEILWLADLLKIYSESGNAQAAATCEYPRRLQGRSV--STITPSELNCERPRITSEPQD--------------------VDVTFGNTVYFTCRAEGNPKPEIIWLRNNNELSMKDDSRLNLLNDGTLMIQ-----NTKETDQGIYQCMAKNVAG--EVKTHEVTLRYYGTPATPTFVIQPQN 340

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. UniProt/SwissProt
Match: sp|Q6AXL3|LRC33_DANRE (Transforming growth factor beta activator LRRC33 OS=Danio rerio OX=7955 GN=nrros PE=2 SV=1)

HSP 1 Score: 53.9138 bits (128), Expect = 2.968e-6
Identity = 37/112 (33.04%), Postives = 58/112 (51.79%), Query Frame = 2

Query:  866 TGL---DLRPDMKFPKLEELALSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDY-MLRYKFGKVYLQGNIFNCNCEMIWIRS------IEADRIKGLKCDNVNFEKH 1171
            TGL   D  P   +  L+ L +S N + ++P  +     NL+LLD+R+N LTT+ S    +L  K   VY+ GN FNC C + W R+      I    +  + C ++N+ +H
Sbjct:  516 TGLQDFDFSP---YTNLKSLNISRNSLSKLPDSLMAL--NLKLLDLRDNSLTTIKSEHASLLAKKLQTVYMNGNAFNC-CHLDWFRTFGENKGIHVADLSEITCLDLNYRRH 621

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. TrEMBL
Match: R7TAS3 (Ig-like domain-containing protein (Fragment) OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_52911 PE=4 SV=1)

HSP 1 Score: 84.7297 bits (208), Expect = 1.120e-13
Identity = 105/486 (21.60%), Postives = 201/486 (41.36%), Query Frame = 2

Query:  158 VCNRQNFNNKPESHCSDIPSKEEWERIKNTTIQTIRCKHSNKSNSLSDIRMKNLQ-------------RLVYIYIGDCNVQSLPMNFFEDLTQLETVYLDNLPIEILKENTFKXXXXXXXXXXXXXXXXKRIHPRFLGDQNKLATLTLTKSNIDPTQLRPTLLTVYNTLAKFYWRRNVQNLIIGKDYFQPFNFESVILEYNGITNTDFLELLNTKELSLKGNPIGIKEKLNWKNYRXXXXXXXXXXXXETGLDLRPDMKFPKLEELALSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDYMLRYKFGKVYLQGNIFNCNCEMIWI-RSIEADRIKGLKCDNVNFEKHVKNQELTRSRILKSKMICTEPLLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWIKNQQTLKIENPPLDRLNNKTVMKNLIIPDDIKTA---DNETYVCRAKSIAGISEIRLEV 1564
             C++QN  + PE    DIP   E        I ++     ++  +L ++ + N +             +L+ + +    +Q L    F  L +L+T+ L++  I  ++   F+  +     +             F     K+  L ++ S++  ++    L+ + ++L + +W+ N + L    + F  F F ++ L  NGI + DFLE + T ELSL  NPIG  +   + N R                         ++ +L LS+     + +     + +L  L + +N +++L      +      + L+GN  +CNCE+ W+ R + A+   G+  +N    + V     T + +      C+EP+               I  +S TL + +         S  CIGEG+PAP + W      +    PP    +++T+ +N  I   I++A   D   Y C A ++AG + +++ V
Sbjct:   37 ACSQQNLTSIPE----DIPVNTEELYFSKNQIHSLSQGALSRYENLKNLLLSNCEIEVIEPNAFSGLIKLITLDLRFNKIQQLQAYLFSGLIKLQTLRLEDNDITSIENFAFQGLNLTRLNLDRNEKLRDISGKAF--HSTKVEQLRISNSSLS-SETAEALVPLKDSLRELHWQNNQKPLRFATEAFVGFTFRALKLNNNGIKDIDFLEGVVTDELSLDDNPIGPIDFSRYPNLR-------------------------QVRKLHLSNTSFSIVLASYFNDMTHLSYLGLEDNGISSLSEDLRPIFMGLQYLLLKGNTLHCNCELRWLKRWLTAE--SGVNINNGEALECVTPSVRTITSMDDVYFTCSEPV---------------IVTISRTLNVSE-----EEGTSLTCIGEGDPAPTIIWSSPNGDVASIPPP----HSRTLTENQGI-FHIRSASLHDRGEYACTAVNLAGNNTVKVHV 463

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. TrEMBL
Match: I1ZII9 (Leucine rich repeat and fibronectin type III domain containing-1 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 82.8037 bits (203), Expect = 4.988e-13
Identity = 88/377 (23.34%), Postives = 165/377 (43.77%), Query Frame = 2

Query:  506 KRIHPRFLGDQNKLATLTLTKSNIDPTQLRPTLLTVYNTLAKFYWRRN-VQNLIIGKDYFQPFNFESVILEYNGITNTDFLELLNTKELSLKGNPIGIKEKLNWKNYRXXXXXXXXXXXXETGLD-LRPDM---KFPKLEELALSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTL-PSLDYMLRYKFGKVYLQGNIFNCNCEMIWIRSIEADRIKGL-KCD----NVNFEKHVKNQELTRSRILKSKMICTEPL----------LKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWIKNQQTLKIENPPLDRLNNKTVMKNLIIPDDIKTADNETYVCRAKSIAGISEIRLEVTKK 1573
            + I    L  Q   + +    + +DP  L+  L  V  ++ +F +  N ++ + + K +F  +    + ++ N   + DFL +  +++L LK N   +K   +   +  L    +  DL   G+    P      F  ++ L + SN I  + + +++  P+LQLLDI  NK+  L P L+ +  YK     L+GN  +CNC++ W+ +    +I+   +C+    N N  +  ++ +L  S++    +IC  P           + ++L+   K     IS+V      Y   +  N L+   C  EG+P P L W      +   +P    +N+ +   N +      +  +  Y+C A +I GIS   L +  K
Sbjct:   29 EHIDFHLLDSQRSFSRIVFDNTTVDPENLKEILKPVRRSIKEFRFINNRIEIVKLPKRFFLDYQLGLLDVQNNLFLDWDFLTVTKSRKLLLK-NSQALKSSFDLSKFSILYLYCELFDLENIGIHGTFPSTISEPFQHVKSLTVKSNSIESLHNSIDQMFPHLQLLDISYNKIKHLQPDLNNLF-YKTEIFKLEGNPLHCNCQVRWLSARYKSKIRDFPRCNFGYRNSNLSESTQSDDLFFSQLATDSLICLPPRAPILSISKAEVPIKLTVSGKDKPNNISIVKKE---YTLVMNSNQLVELNCETEGDPTPTLIWSDEVGPILTRHPS-SHINHSS---NRLTVGLEGSNVSSVYICTASNIEGISFALLNLVSK 396

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. TrEMBL
Match: T1DF80 (LRFN-1 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1)

HSP 1 Score: 80.1073 bits (196), Expect = 5.513e-12
Identity = 116/456 (25.44%), Postives = 199/456 (43.64%), Query Frame = 2

Query:  290 SLSDIRMKNLQRLVYIYIGDCNVQSLPMNFFEDLTQLETVYLDNLPIEILKENTFKXXXXXXXXXXXXXXXXKRIHPRFLGDQNKLATLTLTKSNIDPTQLRPTLLTVYNTLAKFYWRR-NVQNLIIGKDYFQPFNFESVILEYNGITNTDFLELLNTKELSLKGNPIGIKEKLNWKNYRXXXXXXXXXXXXETGL------DLRPDMKFPKLEELALSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDYMLRYKFGKVYLQGNIFNCNCEMIWIRSIEADRIKGLKCDNVNFEK--HVKN----QELTRSRILKSKMICTEPLLK-LQLSDQFKSYDYTISVV------SDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWIKNQQTLKIENPPLDRLNNKTVMKNLIIPDDIKTADNETYVCRAKSIAGISEIRLEVTKKYSKNPMPA 1597
            +L+    + L+ L  I I  C ++++    F     L +V L+NLP+  L+ N F  SSN+IEL L  L +L+ I    L +QNK + L L    I    L+  L  + NT+ +  W   N Q L+I    F  +    + L  N I N +FL    ++++ LK N +          Y  L +  + LDL   G+      ++   M F  L+ L + SN I  +  ++++  PNL   DI  N++  L S      YK     L+GN  +CNCE+ W+ +    +I+     +  F+K   + N    +++  S++    + C  PL   L +S   KS  +T++        S   + Y   + P+  I   C   G+P P L W  + +  K+ +  +  +       N +      +  +  Y+C A +I G+S   + +     + P  A
Sbjct:   77 ALNSRDFEQLESLNSIIIKSCPIETISEKLFSKKEYLGSVTLENLPLRHLR-NIFFKSSNLIELSLINLYNLEYIDSHILENQNKFSRLKLKNVTISTDVLQTVLSPIKNTIRELSWTDVNHQILVIQPMLFSSYKLGLLDLSNNKIENWNFLIYTKSRKILLK-NTVSYTSNFLLSKYASLPQFTQVLDLENIGIFGQFPSNISKPMIF--LKTLNVKSNLIDSLNDNIDQMFPNLLFFDISLNRIKHLQSKLNNFFYKTEYFKLEGNPLHCNCEIRWLFARYKSKIQDFPRCHFGFKKSESINNRNSLKDIYFSQLSTDSLACFPPLPPVLSISKGKKSTMFTVNSTDPQTNSSTISKQYTLVMDPHQRIDLSCETLGDPIPTLTW--SNKKGKVLHRSVLNITTFNSAVNTVTVGLSASEKSLVYMCTASNIEGVSFALVNIISTKIQEPQNA 526

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. TrEMBL
Match: A0A267GSH0 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig029737g2 PE=4 SV=1)

HSP 1 Score: 79.337 bits (194), Expect = 9.710e-12
Identity = 109/402 (27.11%), Postives = 168/402 (41.79%), Query Frame = 2

Query:  287 NSLSDIRMKNLQRLVYIYIGDCNVQSLPMNFFEDLTQLETVYLDNLPIEILKENTFKXXXXXXXXXXXXXXXXKRIHPRFLGDQNKLATLTLTKSNIDPTQL------RPT-LLTVYNTLAKFYWRRNVQNLIIGKDYFQPFNFESVILEYNGITNTDFLELLNTKELSLKGN--PIGIKEKLNWKNYRXXXXXXXXXXXXE-TGLDLRPD---MKFPKLEELALSSNGIHQI-PSHVEKFLPNLQLLDIRNNKLTTL-------PSLDYML--RYKFGKVYLQGNIFNCNCEMIWIRS---IEADRIKGLKCDNVNFEKHVKNQELTRSRILKSKMIC---TEPLLKLQL-SDQFKSYDYTISVVSDTLQIY---KFDLYPNHLISWQCIGEGNPAPRLKW 1393
            ++LS    + L  L  I I  C + +LP   F  L  L +V LDN+    L    F+ S +I ELIL          P  L D  +L  L L +  +   QL       PT ++     +   Y       L +       F+  S+ L  NGIT+  FL  +   E++L  N  P+G   ++  +           L   E +GL+  P    + FP+L EL L+SN I Q+ PS +   L  L  LD+  N++ TL       P L  +L    + G +YL  N  +CNCE+ WI     + +  ++ L C +  F   +        R+ K ++ C   T P + LQ     F S D  +  V++   I    + +L     ++  C    +PAP L W
Sbjct:   96 SALSPGVFRRLVELREISIRSCPIGALPAGLFAHLPALTSVTLDNMLFTSLPPGLFQGSQSIAELILQRCHEYTSQTPALLVDTPRLRLLKLIEVGLSGEQLDNLLKSAPTGMMQTLEVIMTLY-----PPLRLSGATLSAFSLTSLSLSNNGITDFAFLPSVGAAEVTLSYNRAPLG---RIELETSSIQPNRRVTLLRLEHSGLNEIPSFLSVVFPELAELNLASNIIQQLEPSRLAN-LSRLVRLDLSGNQIQTLSDWRRLQPLLSAILYRDRQSGHIYLAENPIHCNCELSWIYDNPILSSSLLRDLTCQSGQFVGQLL------VRLQKHQLRCRPPTVPDVTLQYWPAIFTSSDAGVPRVANETVILPGQQCNLTRRRNVTLTCSSSADPAPGLAW 482

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. TrEMBL
Match: A0A267G4B5 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig034245g1 PE=4 SV=1)

HSP 1 Score: 78.1814 bits (191), Expect = 2.152e-11
Identity = 111/405 (27.41%), Postives = 170/405 (41.98%), Query Frame = 2

Query:  287 NSLSDIRMKNLQRLVYIYIGDCNVQSLPMNFFEDLTQLETVYLDNLPIEILKENTFKXXXXXXXXXXXXXXXXKRIHPRFLGDQNKLATLTLTKSNIDPTQLRPTLLTVYNTLAKFYWRRNVQNLIIGKDYFQP----------FNFESVILEYNGITNTDFLELLNTKELSLKGN--PIGIKEKLNWKNYRXXXXXXXXXXXXE-TGLDLRPD---MKFPKLEELALSSNGIHQI-PSHVEKFLPNLQLLDIRNNKLTTL-------PSLDYMLR--YKFGKVYLQGNIFNCNCEMIWIRS---IEADRIKGLKCDNVNFEKHVKNQELTRSRILKSKMIC---TEPLLKLQL-SDQFKSYDYTISVVSDTLQIY---KFDLYPNHLISWQCIGEGNPAPRLKW 1393
            ++LS    + L  L  I I  C + +LP   F  L  L +V LDN+    L    F+ S +I ELIL          P  L D  +L  L L +  ++  QL        + L K    R +Q L +    + P          F+  S+ L  NGIT+  FL  +   E++L  N  P+G   ++  +           L   E +GL+  P    + FP+L EL L+SN I Q+ PS +   L  L  LD+  N++ TL       P L  +L    + G +YL  N  +CNCE+ WI     + +  ++ L C +  F   +        R+ K ++ C   T P + LQ     F S D     V++   I    + +L     ++  C    +PAP L W
Sbjct:   86 SALSPGVFRRLVELREISIRSCPIGALPAGLFAHLPALTSVTLDNMLFTSLPPGLFQGSQSIAELILQRCHEYTSQTPALLVDTPRLRLLKLIEVGLNGEQL--------DNLLKSAPTRMMQTLEVIMTLYPPLRLSGATLSAFSLTSLSLSNNGITDFAFLPSVGAAEVTLSYNRAPLG---RIELETSSIQPNRRVTLLRLEHSGLNEIPSFLSVVFPELAELNLASNIIQQLEPSRLAN-LSRLVRLDLSGNQIQTLSDWRRLQPLLSAILYRDRQSGHIYLAENPIHCNCELSWIYDNPILSSSLLRDLTCQSGQFVGQLL------VRLQKHQLRCRPPTVPDVTLQYWPAIFTSSDAGEPRVANETVILPGQQCNLTRRRNVTLTCSSSADPAPGLAW 472

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Cavefish
Match: ENSAMXT00000018470.2 (pep primary_assembly:Astyanax_mexicanus-2.0:3:54654459:54659878:-1 gene:ENSAMXG00000017923.2 transcript:ENSAMXT00000018470.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 50.8322 bits (120), Expect = 2.565e-6
Identity = 28/74 (37.84%), Postives = 47/74 (63.51%), Query Frame = 2

Query:  905 LEELALSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDYMLRYKFGKVYLQGNIFNCNCEMIWI-RSIEA 1123
            L  L L  N I  I  H  K L  LQ+L++RNN+L++LP+++ +   K   +Y+ GN +NC+C++  + RS++A
Sbjct:  384 LVRLDLKGNNIAMIKEHELKSLKRLQVLNLRNNRLSSLPAMNLL--PKLRTLYVDGNPWNCSCDLFKVKRSLQA 455

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Cavefish
Match: flrt3 (fibronectin leucine rich transmembrane protein 3 [Source:NCBI gene;Acc:103023981])

HSP 1 Score: 50.0618 bits (118), Expect = 5.752e-6
Identity = 65/274 (23.72%), Postives = 105/274 (38.32%), Query Frame = 2

Query:  692 NFESVILEYN-----GITNTDFLELLNTKELSLKGNPIGIKEKLNWKNYRXXXXXXXXXXXXETGLDLRPDMKFP--KLEELALSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDYMLRYKFGKVYLQGNIFNCNCEMIWIRSI----------------EADRIKGLK----------CDNV----NFEKHVKNQELTRSRILKSKMICTEPLLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHL-ISWQCIGEGNPAPRLKWIK 1399
            N + ++L+ N     GI    F+ L+N  ELSL      ++  L +                       P    P   LE+L L  N I ++P+    FL  L  LD+  NKLT+LP   +       ++ L+ N ++CNC M W+R                    D++KG+           C +      +E    +  L  SR      +   P++K    D  K+Y  T  +    + I      P+ + ISW+ + +   A RL W+K
Sbjct:  200 NLKRLVLDGNLLNNRGIGEMAFVNLINLTELSL------VRNSLTY-----------------------PPANLPGSSLEKLQLQDNHIDRVPAGAFAFLRQLYRLDLSGNKLTSLPMGVFDDLDNLTQLLLRNNPWHCNCRMKWVRDWLRLLPAKVNVRGFMCQGPDKVKGMAIKDLATELFDCSDTEVSPTYETSTVSNTLPPSRPQWPIYVTKRPVIKGP--DFGKNYRSTTPLSRKIITISVKSSSPDAVHISWR-VSQPMTALRLSWLK 441

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Cavefish
Match: nrros (negative regulator of reactive oxygen species [Source:NCBI gene;Acc:103028171])

HSP 1 Score: 50.0618 bits (118), Expect = 5.970e-6
Identity = 35/92 (38.04%), Postives = 52/92 (56.52%), Query Frame = 2

Query:  866 TGL---DLRPDMKFPKLEELALSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDY-MLRYKFGKVYLQGNIFNCNCEMIWIRSIEADR 1129
            TGL   D  P   +  L+ L +S+N I ++P  +     NL+LLD+RNN L+T+ S D  +L  +   VY+ GN FNC C++ W R  E  +
Sbjct:  515 TGLQNFDFSP---YRHLKFLNISNNSIWELPKSLISL--NLKLLDLRNNMLSTIQSEDATVLAQRVRAVYVNGNAFNC-CQLEWYRMFEESK 600

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Sea Lamprey
Match: pxdn (peroxidasin [Source:ZFIN;Acc:ZDB-GENE-140415-2])

HSP 1 Score: 65.0846 bits (157), Expect = 3.585e-11
Identity = 55/234 (23.50%), Postives = 98/234 (41.88%), Query Frame = 2

Query:  902 KLEELALSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDYMLRYKFGKVYLQGNIFNCNCEMIWIRS-IEADRIKGLKCDNVNFEKHVKNQELTRSRILKSKMICTEPLLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWIKNQQTLKI-ENPPLDRLNNKTVMKNLIIPDDIKTADNETYVCRAKSIAGISEIRL-EVTKKYSKNPMP 1594
             LE+L +  N I  +  +    LP L+ L + NN+L+ + +  +       ++ L  N   C+CE++W+   + A    G        E   + Q  + S I   +  C  P +                    T + +  D+ P + +  +C  EGNP P + W+ N   + + E+   + L + T+M       D +  D  TY C A+++AG  E++  EV  +Y   P P
Sbjct:   72 SLEQLYIHFNHIEVLEPNTFVDLPKLERLFLHNNRLSRIATGTFTQLSSLRRLRLDSNRLVCDCELVWLAELLRAFAGSGGTLAAATCEHPRRLQGRSVSSITAQEFHCESPRI--------------------TSEPHDVDVTPGNTVYLRCRAEGNPKPAIIWLHNSNEIAMAEDERRNLLQDGTLMIR-----DTRHTDQGTYQCMARNVAG--EVKAPEVVLRYFDVPAP 278

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Medaka
Match: pxdn (peroxidasin [Source:NCBI gene;Acc:101162089])

HSP 1 Score: 68.5514 bits (166), Expect = 1.433e-11
Identity = 61/241 (25.31%), Postives = 106/241 (43.98%), Query Frame = 2

Query:  905 LEELALSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDYMLRYKFGKVYLQGNIFNCNCEMIWIRSIEADRIKGLKCDNVNFEKHVKNQELTRSRILKSKMICTEPLLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWIKNQQTLKI-ENPPLDRLNNKTVMKNLIIPDDIKTADNETYVCRAKSIAGISEIRL-EVTKKYSKNPMPALGQIDLQN 1621
            LE+L L  N I  +       LP L+ L + NN++T L    +       ++ L  N  NCNCE++W+    AD +K L  ++ N +        +R   L+ + + T             + +    +   T +    D+   + + + C  EGNP P++ W++N   L + ++  L+ L + T+M       D +  D   Y C AK++AG  E++  +VT +Y   P      I  QN
Sbjct:  134 LEQLYLHFNNIESLEPESFSHLPKLERLFLHNNRITQLVPGTFSHLSAMKRLRLDSNALNCNCEVLWL----ADLLK-LYAESGNAQAAATCDHPSR---LQGRSVAT-----------LTAEELNCELPRITSEPQDVDVTLGNTVYFTCRAEGNPKPQIIWLRNNNALNMRDDSRLNLLEDGTLMIQ-----DTRETDQGVYQCMAKNVAG--EVKTSQVTLRYFGAPTRPSFVIQPQN 348

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Medaka
Match: pxdn (peroxidasin [Source:NCBI gene;Acc:101162089])

HSP 1 Score: 65.4698 bits (158), Expect = 1.233e-10
Identity = 60/241 (24.90%), Postives = 105/241 (43.57%), Query Frame = 2

Query:  905 LEELALSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDYMLRYKFGKVYLQGNIFNCNCEMIWIRSIEADRIKGLKCDNVNFEKHVKNQELTRSRILKSKMICTEPLLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWIKNQQTLKI-ENPPLDRLNNKTVMKNLIIPDDIKTADNETYVCRAKSIAGISEIRL-EVTKKYSKNPMPALGQIDLQN 1621
            L+ L L  N I  +       LP L+ L + NN++T L    +       ++ L  N  NCNCE++W+    AD +K L  ++ N +        +R   L+ + + T             + +    +   T +    D+   + + + C  EGNP P++ W++N   L + ++  L+ L + T+M       D +  D   Y C AK++AG  E++  +VT +Y   P      I  QN
Sbjct:  110 LKYLYLHFNNIESLEPESFSHLPKLERLFLHNNRITQLVPGTFSHLSAMKRLRLDSNALNCNCEVLWL----ADLLK-LYAESGNAQAAATCDHPSR---LQGRSVAT-----------LTAEELNCELPRITSEPQDVDVTLGNTVYFTCRAEGNPKPQIIWLRNNNALNMRDDSRLNLLEDGTLMIQ-----DTRETDQGVYQCMAKNVAG--EVKTSQVTLRYFGAPTRPSFVIQPQN 324

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Medaka
Match: pxdn (peroxidasin [Source:NCBI gene;Acc:101162089])

HSP 1 Score: 59.6918 bits (143), Expect = 8.436e-9
Identity = 52/209 (24.88%), Postives = 95/209 (45.45%), Query Frame = 2

Query:  968 LPNLQLLDIRNNKLTTLPSLDYMLRYKFGKVYLQGNIFNCNCEMIWIRSIEADRIKGLKCDNVNFEKHVKNQELTRSRILKSKMICTEPLLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWIKNQQTLKI-ENPPLDRLNNKTVMKNLIIPDDIKTADNETYVCRAKSIAGISEIRL-EVTKKYSKNP 1588
            L NL+ L + NN++T L    +       ++ L  N  NCNCE++W+    AD +K L  ++ N +        +R   L+ + + T             + +    +   T +    D+   + + + C  EGNP P++ W++N   L + ++  L+ L + T+M       D +  D   Y C AK++AG  E++  +VT +Y   P
Sbjct:  107 LENLKYLFLHNNRITQLVPGTFSHLSAMKRLRLDSNALNCNCEVLWL----ADLLK-LYAESGNAQAAATCDHPSR---LQGRSVAT-----------LTAEELNCELPRITSEPQDVDVTLGNTVYFTCRAEGNPKPQIIWLRNNNALNMRDDSRLNLLEDGTLMIQ-----DTRETDQGVYQCMAKNVAG--EVKTSQVTLRYFGAP 289

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Medaka
Match: lrfn1 (leucine rich repeat and fibronectin type III domain containing 1 [Source:NCBI gene;Acc:101167138])

HSP 1 Score: 51.9878 bits (123), Expect = 1.352e-6
Identity = 86/374 (22.99%), Postives = 139/374 (37.17%), Query Frame = 2

Query:  533 DQNKLATLTLTKSNIDPTQLRPTLLTVYNTLAKFYWRRNVQNLIIGKDYFQPF-NFESVILEYNGI---TNTDFLELLNT-KELSLKGNPIGIKEKLNWKNYRXXXXXXXXXXXXETGLDLRPDMKFPKLEELALSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLP----------------SLDYMLRYKFGKVYLQGNIFNCNCEMIWIRSIEADRIKGLKCDNVNFEKHVKNQELTRSRILKSKMICTEPLLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWIK--------NQQTLKIENPPLDRLNNKTVMKNLIIPDDIKTADNETYVCRAKSIAGISEIRLEVT 1567
            +   L  LTL+++ I  +Q+ P       +L   +   N  N II  D+F+   N   +IL  N I    +T F E ++T ++L L  N           N R              GL      +   +  L L  N I  I +     L  L  LD+ +N+L  LP                S    L   FG     GN  +CNCE++W+R +  +       +     +H+ ++      I + + IC  PL+   ++   KSY                 +     ++ +C   G+P P + W          N +T+  +N  LD           I+   +K  DN  Y C A + AGI+   +E+T
Sbjct:   73 NMTSLVHLTLSRNTI--SQIVPHAFVGLRSLRALHMDGNRLN-IIKSDHFKGLINLRHLILGNNQIHEVASTSFDEFVSTIEDLDLSNN-----------NLR--------------GLPWEAIARMSNINTLTLDHNLIDHIEAGTFTLLTKLVRLDMTSNRLQKLPPDSLFQHAQVLSEVKGSSSSTLAVSFG-----GNPLHCNCELLWLRRLTRED----DLETCASPEHLMDKYFW--SIQEEEFICEPPLITKHVAS--KSY-----------------VMEGQGVTLKCKAVGDPDPFIHWQSPDGKLVHNNSRTILYDNGTLD-----------ILISTLK--DNGAYNCVASNAAGIATAAVEIT 375

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Medaka
Match: lrrtm4l1 (leucine-rich repeat transmembrane neuronal protein 4-like [Source:NCBI gene;Acc:101154965])

HSP 1 Score: 51.6026 bits (122), Expect = 1.899e-6
Identity = 79/310 (25.48%), Postives = 141/310 (45.48%), Query Frame = 2

Query:  380 FEDLTQLETVYLDNLPIEILKENTFKXXXXXXXXXXXXXXXXKRIHPRFLGDQNKLATLTLTKSNIDPTQLRPTLLTVYNTLAKFYWRRNVQNLIIGKDYFQPFNFESVILEYN---GITNTDFLELLNTKELSLKGNPIGIKEKLNW------KNYRXXXXXXXXXXXXETGLDLRPDMKFPKLEELALSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDYMLRYKFGKVYLQGNIFNCN---CEMI-WIRSIEADRIKGLKCDNVNFEKHVKNQELTRSRIL--KSKMICTE-PLLKLQLSDQ 1261
            F  L+Q+  +YLD+  I  +    F+    + ELILS        +  F G  N L +L L+ + ++   L+P        L   + R N  + I  + + +  + E + L YN    +T T FL L    EL L+ N      ++N+       N R L     ++ +   GL   P + +  L++L LS N I  +   V   LPNLQ+L++ +NKL+ +             + L GN+++C    C ++ W+R+    +   + C +  + +  K  E+TR+  +  ++  + TE PL  L+L+ +
Sbjct:   99 FAHLSQILWIYLDHNQISAIDSRAFQGVRRLKELILSSNRITSLHNSTFHGIPN-LRSLDLSFNKLE--ILQPGQFHGLRKLQNLHLRSNGLSNIPIRVFLECRSLEFLDLGYNRIKALTRTTFLGLQRLMELHLEHNQF---TRINFFLFPRLANLRSLYLQWNRIRVVNQGL---PWIWY-TLQKLDLSGNEIQTLDPAVFHCLPNLQVLNLESNKLSNVSQEAVSAWISLTSISLAGNMWDCGTGICPIVAWLRNFRGSKDTTMICSSPKYMQGEKIMEVTRNHAICEETDYVLTETPLPTLELTSE 398

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. Planmine SMEST
Match: SMESG000080200.1 (SMESG000080200.1)

HSP 1 Score: 1059.67 bits (2739), Expect = 0.000e+0
Identity = 561/563 (99.64%), Postives = 561/563 (99.64%), Query Frame = 2

Query:    5 DWSVQKSLXXXXXXXXXXNYNFVVDEIFLIEMWIYLLIGAISVVTTDQEGLVCNRQNFNNKPESHCSDIPSKEEWERIKNTTIQTIRCKHSNKSNSLSDIRMKNLQRLVYIYIGDCNVQSLPMNFFEDLTQLETVYLDNLPIEILKENTFKXXXXXXXXXXXXXXXXKRIHPRFLGDQNKLATLTLTKSNIDPTQLRPTLLTVYNTLAKFYWRRNVQNLIIGKDYFQPFNFESVILEYNGITNTDFLELLNTKELSLKGNPIGIKEKLNWKNYRXXXXXXXXXXXXETGLDLRPDMKFPKLEELALSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDYMLRYKFGKVYLQGNIFNCNCEMIWIRSIEADRIKGLKCDNVNFEKHVKNQELTRSRILKSKMICTEPLLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWIKNQQTLKIENPPLDRLNNKTVMKNLIIPDDIKTADNETYVCRAKSIAGISEIRLEVTKKYSKNPMPALGQIDLQNFATENSKPSFLNLFLLMIINAFIR 1693
            DWSV KSLIMIII DRIINYNFVVDEIFLIEMWIYLLIGAISVVTTDQEGLVCNRQNFNNKPESHCSDIPSKEEWERIKNTTIQTIRCKHSNKSNSLSDIRMKNLQRLVYIYIGDCNVQSLPMNFFEDLTQLETVYLDNLPIEILKENTFKNSSNIIELILSGLGSLKRIHPRFLGDQNKLATLTLTKSNIDPTQLRPTLLTVYNTLAKFYWRRNVQNLIIGKDYFQPFNFESVILEYNGITNTDFLELLNTKELSLKGNPIGIKEKLNWKNYRKLSKSLKKLDLSETGLDLRPDMKFPKLEELALSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDYMLRYKFGKVYLQGNIFNCNCEMIWIRSIEADRIKGLKCDNVNFEKHVKNQELTRSRILKSKMICTEPLLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWIKNQQTLKIENPPLDRLNNKTVMKNLIIPDDIKTADNETYVCRAKSIAGISEIRLEVTKKYSKNPMPALGQIDLQNFATENSKPSFLNLFLLMIINAFIR
Sbjct:   17 DWSVHKSLIMIIIIDRIINYNFVVDEIFLIEMWIYLLIGAISVVTTDQEGLVCNRQNFNNKPESHCSDIPSKEEWERIKNTTIQTIRCKHSNKSNSLSDIRMKNLQRLVYIYIGDCNVQSLPMNFFEDLTQLETVYLDNLPIEILKENTFKNSSNIIELILSGLGSLKRIHPRFLGDQNKLATLTLTKSNIDPTQLRPTLLTVYNTLAKFYWRRNVQNLIIGKDYFQPFNFESVILEYNGITNTDFLELLNTKELSLKGNPIGIKEKLNWKNYRKLSKSLKKLDLSETGLDLRPDMKFPKLEELALSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDYMLRYKFGKVYLQGNIFNCNCEMIWIRSIEADRIKGLKCDNVNFEKHVKNQELTRSRILKSKMICTEPLLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWIKNQQTLKIENPPLDRLNNKTVMKNLIIPDDIKTADNETYVCRAKSIAGISEIRLEVTKKYSKNPMPALGQIDLQNFATENSKPSFLNLFLLMIINAFIR 579

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. Planmine SMEST
Match: SMESG000080200.1 (SMESG000080200.1)

HSP 1 Score: 1022.31 bits (2642), Expect = 0.000e+0
Identity = 532/532 (100.00%), Postives = 532/532 (100.00%), Query Frame = 2

Query:   98 MWIYLLIGAISVVTTDQEGLVCNRQNFNNKPESHCSDIPSKEEWERIKNTTIQTIRCKHSNKSNSLSDIRMKNLQRLVYIYIGDCNVQSLPMNFFEDLTQLETVYLDNLPIEILKENTFKXXXXXXXXXXXXXXXXKRIHPRFLGDQNKLATLTLTKSNIDPTQLRPTLLTVYNTLAKFYWRRNVQNLIIGKDYFQPFNFESVILEYNGITNTDFLELLNTKELSLKGNPIGIKEKLNWKNYRXXXXXXXXXXXXETGLDLRPDMKFPKLEELALSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDYMLRYKFGKVYLQGNIFNCNCEMIWIRSIEADRIKGLKCDNVNFEKHVKNQELTRSRILKSKMICTEPLLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWIKNQQTLKIENPPLDRLNNKTVMKNLIIPDDIKTADNETYVCRAKSIAGISEIRLEVTKKYSKNPMPALGQIDLQNFATENSKPSFLNLFLLMIINAFIR 1693
            MWIYLLIGAISVVTTDQEGLVCNRQNFNNKPESHCSDIPSKEEWERIKNTTIQTIRCKHSNKSNSLSDIRMKNLQRLVYIYIGDCNVQSLPMNFFEDLTQLETVYLDNLPIEILKENTFKNSSNIIELILSGLGSLKRIHPRFLGDQNKLATLTLTKSNIDPTQLRPTLLTVYNTLAKFYWRRNVQNLIIGKDYFQPFNFESVILEYNGITNTDFLELLNTKELSLKGNPIGIKEKLNWKNYRKLSKSLKKLDLSETGLDLRPDMKFPKLEELALSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDYMLRYKFGKVYLQGNIFNCNCEMIWIRSIEADRIKGLKCDNVNFEKHVKNQELTRSRILKSKMICTEPLLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWIKNQQTLKIENPPLDRLNNKTVMKNLIIPDDIKTADNETYVCRAKSIAGISEIRLEVTKKYSKNPMPALGQIDLQNFATENSKPSFLNLFLLMIINAFIR
Sbjct:    1 MWIYLLIGAISVVTTDQEGLVCNRQNFNNKPESHCSDIPSKEEWERIKNTTIQTIRCKHSNKSNSLSDIRMKNLQRLVYIYIGDCNVQSLPMNFFEDLTQLETVYLDNLPIEILKENTFKNSSNIIELILSGLGSLKRIHPRFLGDQNKLATLTLTKSNIDPTQLRPTLLTVYNTLAKFYWRRNVQNLIIGKDYFQPFNFESVILEYNGITNTDFLELLNTKELSLKGNPIGIKEKLNWKNYRKLSKSLKKLDLSETGLDLRPDMKFPKLEELALSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDYMLRYKFGKVYLQGNIFNCNCEMIWIRSIEADRIKGLKCDNVNFEKHVKNQELTRSRILKSKMICTEPLLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWIKNQQTLKIENPPLDRLNNKTVMKNLIIPDDIKTADNETYVCRAKSIAGISEIRLEVTKKYSKNPMPALGQIDLQNFATENSKPSFLNLFLLMIINAFIR 532

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. Planmine SMEST
Match: SMESG000080200.1 (SMESG000080200.1)

HSP 1 Score: 935.636 bits (2417), Expect = 0.000e+0
Identity = 488/491 (99.39%), Postives = 490/491 (99.80%), Query Frame = 2

Query:   98 MWIYLLIGAISVVTTDQEGLVCNRQNFNNKPESHCSDIPSKEEWERIKNTTIQTIRCKHSNKSNSLSDIRMKNLQRLVYIYIGDCNVQSLPMNFFEDLTQLETVYLDNLPIEILKENTFKXXXXXXXXXXXXXXXXKRIHPRFLGDQNKLATLTLTKSNIDPTQLRPTLLTVYNTLAKFYWRRNVQNLIIGKDYFQPFNFESVILEYNGITNTDFLELLNTKELSLKGNPIGIKEKLNWKNYRXXXXXXXXXXXXETGLDLRPDMKFPKLEELALSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDYMLRYKFGKVYLQGNIFNCNCEMIWIRSIEADRIKGLKCDNVNFEKHVKNQELTRSRILKSKMICTEPLLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWIKNQQTLKIENPPLDRLNNKTVMKNLIIPDDIKTADNETYVCRAKSIAGISEIRLEVTK 1570
            MWIYLLIGAISVVTTDQEGLVCNRQNFNNKPESHCSDIPSKEEWERIKNTTIQTIRCKHSNKSNSLSDIRMKNLQRLVYIYIGDCNVQSLPMNFFEDLTQLETVYLDNLPIEILKENTFKNSSNIIELILSGLGSLKRIHPRFLGDQNKLATLTLTKSNIDPTQLRPTLLTVYNTLAKFYWRRNVQNLIIGKDYFQPFNFESVILEYNGITNTDFLELLNTKELSLKGNPIGIKEKLNWKNYRKLSKSLKKLDLSETGLDLRPDMKFPKLEELALSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDYMLRYKFGKVYLQGNIFNCNCEMIWIRSIEADRIKGLKCDNVNFEKHVKNQELTRSRILKSKMICTEPLLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWIKNQQTLKIENPPLDRLNNKTVMKNLIIPDDIKTADNETYVCRAKSIAGISEIRLE+ +
Sbjct:    1 MWIYLLIGAISVVTTDQEGLVCNRQNFNNKPESHCSDIPSKEEWERIKNTTIQTIRCKHSNKSNSLSDIRMKNLQRLVYIYIGDCNVQSLPMNFFEDLTQLETVYLDNLPIEILKENTFKNSSNIIELILSGLGSLKRIHPRFLGDQNKLATLTLTKSNIDPTQLRPTLLTVYNTLAKFYWRRNVQNLIIGKDYFQPFNFESVILEYNGITNTDFLELLNTKELSLKGNPIGIKEKLNWKNYRKLSKSLKKLDLSETGLDLRPDMKFPKLEELALSSNGIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDYMLRYKFGKVYLQGNIFNCNCEMIWIRSIEADRIKGLKCDNVNFEKHVKNQELTRSRILKSKMICTEPLLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWIKNQQTLKIENPPLDRLNNKTVMKNLIIPDDIKTADNETYVCRAKSIAGISEIRLEIYR 491

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. Planmine SMEST
Match: SMESG000051501.1 (SMESG000051501.1)

HSP 1 Score: 127.487 bits (319), Expect = 5.111e-31
Identity = 154/559 (27.55%), Postives = 249/559 (44.54%), Query Frame = 2

Query:   86 FLIEMWIYLLIGAISVVTTDQEGLVCNRQNFNNKPESHCSDIPSKEEWERIK-NTTIQTIRCKHSNKSNSLSDIRMKNLQRLVYIYIGDCNVQSLPMNFFEDLTQLETVYLDNLPIEILKENTFKXXXXXXXXXXXXXXXXKRIHPRFLGDQNKLATLTLTKSNIDPTQLRPTLLTVYNTLAKFYWRRNVQNLIIGKDYFQPFNFESVILEYNGITNTDFLELLNTKELSLKGNPIGIKEKLNWKNYRXXXXXXXXXXXXETGLD----LRPDMKFPKLEELALSSN---GIHQIPSHVEKFLPNLQLLDIRNNKLTTLP-SLDYMLRYKFGKVYLQGNIFNCNCEMIWIRSIEADRIKGLKCDNVNFEKHVKNQELTRSRI--LKSKMICTEPLLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWIK-NQQTLKIENPPLDRLNNKTVMKNLIIPDDIKTADNETY---VCRAKSIAGISEIRLEVTKKYSK-NPMPALGQIDLQNFATENS--------KPSFLNLFLLMIINAFI 1690
            F+I ++  LL    S  TT         +NF    ++ C+ IP + +  RI  +     I+C +S+K   + D   +    LV+I I  C +   P + F++L+ L  V+L  L I  + ++ FKNS N+  L    L +L++I P  L D  ++  + L   NI  T +   LL V+ TL    W  N++ L    DYF+ F F+ + L  N I N++F E L   E+ L  N I      +WKNY+ L    K L +    +     L     F  + +L +++N   G H++  ++     NL  LD  +N++  L  S+ Y+L  KF ++    N   C CE+ W+R+    +IK +KC  V       + E+  +       K  C  P   L++    K    +I+ ++       FDLY    I  +CI  G+P P L++I  N+ T       L+  +  T+  +       + ++N  Y    C   +  G S IRL++ K Y K     ++  I    F  E S        K +FL  FL M+IN  I
Sbjct:    3 FVIVIYYILLSNTFSDATT-----CVTSKNFE-IHQTECTSIPDENDLLRIPPDINYLIIKCNYSSKIKKIFD--FQRFSNLVFISISKCRINQFPSSTFQNLSFLREVHLAELNITEIPDDIFKNSVNVKRLSFIHLANLEKISPFSLRDCFQVEEINLGGLNISTTSIHLFLLVVHKTLKVLTWNNNLKRLKFSSDYFKHFQFDELRLIRNQIGNSEFFENLQAAEVHLDFNEIS--NNFDWKNYKHLISDTKVLSIGHNIIHGVFPLVHSGFFANITKLFINNNQIIGFHKMFPYI---FQNLSYLDASSNRIVKLSESMKYVL--KFRQIIFSNNPLFCGCELNWLRN-SNPKIK-IKCSKVIQANDQSDIEVVENYQDPFYPKSHCYPPKTYLEIESAKKILKISIAEMT-------FDLYSCEFIQLRCIAVGDPLPTLEFINFNEATFG--KSSLNFYDEITIATSRKTIRHSQLSENSKYNQLHCLGTNSYGKSIIRLQLNKMYGKRKSKKSIEGIKKSKFCRERSSRLTANSLKVTFL-FFLPMLINFII 534

[Close]

BLAST of negative regulator of reactive oxygen species-like vs. Planmine SMEST
Match: SMESG000051501.1 (SMESG000051501.1)

HSP 1 Score: 121.324 bits (303), Expect = 4.246e-29
Identity = 140/500 (28.00%), Postives = 225/500 (45.00%), Query Frame = 2

Query:  260 IRCKHSNKSNSLSDIRMKNLQRLVYIYIGDCNVQSLPMNFFEDLTQLETVYLDNLPIEILKENTFKXXXXXXXXXXXXXXXXKRIHPRFLGDQNKLATLTLTKSNIDPTQLRPTLLTVYNTLAKFYWRRNVQNLIIGKDYFQPFNFESVILEYNGITNTDFLELLNTKELSLKGNPIGIKEKLNWKNYRXXXXXXXXXXXXETGLD----LRPDMKFPKLEELALSSN---GIHQIPSHVEKFLPNLQLLDIRNNKLTTLP-SLDYMLRYKFGKVYLQGNIFNCNCEMIWIRSIEADRIKGLKCDNVNFEKHVKNQELTRSRI--LKSKMICTEPLLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAPRLKWIK-NQQTLKIENPPLDRLNNKTVMKNLIIPDDIKTADNETY---VCRAKSIAGISEIRLEVTKKYSK-NPMPALGQIDLQNFATENS--------KPSFLNLFLLMIINAFI 1690
            I+C +S+K   + D   +    LV+I I  C +   P + F++L+ L  V+L  L I  + ++ FKNS N+  L    L +L++I P  L D  ++  + L   NI  T +   LL V+ TL    W  N++ L    DYF+ F F+ + L  N I N++F E L   E+ L  N I      +WKNY+ L    K L +    +     L     F  + +L +++N   G H++  ++     NL  LD  +N++  L  S+ Y+L  KF ++    N   C CE+ W+R+    +IK +KC  V       + E+  +       K  C  P   L++    K    +I+ ++       FDLY    I  +CI  G+P P L++I  N+ T       L+  +  T+  +       + ++N  Y    C   +  G S IRL++ K Y K     ++  I    F  E S        K +FL  FL M+IN  I
Sbjct:   14 IKCNYSSKIKKIFD--FQRFSNLVFISISKCRINQFPSSTFQNLSFLREVHLAELNITEIPDDIFKNSVNVKRLSFIHLANLEKISPFSLRDCFQVEEINLGGLNISTTSIHLFLLVVHKTLKVLTWNNNLKRLKFSSDYFKHFQFDELRLIRNQIGNSEFFENLQAAEVHLDFNEIS--NNFDWKNYKHLISDTKVLSIGHNIIHGVFPLVHSGFFANITKLFINNNQIIGFHKMFPYI---FQNLSYLDASSNRIVKLSESMKYVL--KFRQIIFSNNPLFCGCELNWLRN-SNPKIK-IKCSKVIQANDQSDIEVVENYQDPFYPKSHCYPPKTYLEIESAKKILKISIAEMT-------FDLYSCEFIQLRCIAVGDPLPTLEFINFNEATFG--KSSLNFYDEITIATSRKTIRHSQLSENSKYNQLHCLGTNSYGKSIIRLQLNKMYGKRKSKKSIEGIKKSKFCRERSSRLTANSLKVTFL-FFLPMLINFII 492

The following BLAST results are available for this feature:

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Human
BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Celegans
BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Fly
BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Zebrafish
BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Xenopus
BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Mouse
BLAST of negative regulator of reactive oxygen species-like vs. UniProt/SwissProt
BLAST of negative regulator of reactive oxygen species-like vs. TrEMBL
BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Cavefish
BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Sea Lamprey
BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Yeast
BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Nematostella
BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Medaka
BLAST of negative regulator of reactive oxygen species-like vs. Planmine SMEST

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Pxn	5.298e-7	21.92	gene:FBgn0011828 transcript:FBtr0072950	[more]
Pxn	1.674e-6	21.92	gene:FBgn0011828 transcript:FBtr0072954	[more]
Pxn	1.674e-6	21.92	gene:FBgn0011828 transcript:FBtr0072951	[more]
Pxn	1.674e-6	21.92	gene:FBgn0011828 transcript:FBtr0072952	[more]
Pxn	1.674e-6	21.92	gene:FBgn0011828 transcript:FBtr0072953	[more]

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pxdn	7.093e-12	24.24	peroxidasin [Source:ZFIN;Acc:ZDB-GENE-140415-2]	[more]
pxdn	1.005e-11	24.24	peroxidasin [Source:ZFIN;Acc:ZDB-GENE-140415-2]	[more]
pxdn	1.103e-11	24.24	peroxidasin [Source:ZFIN;Acc:ZDB-GENE-140415-2]	[more]
pxdn	1.103e-11	24.24	peroxidasin [Source:ZFIN;Acc:ZDB-GENE-140415-2]	[more]
pxdn	7.808e-11	24.07	peroxidasin [Source:ZFIN;Acc:ZDB-GENE-140415-2]	[more]

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
polr1e	3.510e-11	24.08	polymerase (RNA) I polypeptide E [Source:Xenbase;A...	[more]
polr1e	3.622e-11	24.08	polymerase (RNA) I polypeptide E [Source:Xenbase;A...	[more]
polr1e	4.117e-11	24.08	polymerase (RNA) I polypeptide E [Source:Xenbase;A...	[more]
polr1e	2.810e-10	24.02	polymerase (RNA) I polypeptide E [Source:Xenbase;A...	[more]
polr1e	1.665e-6	24.26	polymerase (RNA) I polypeptide E [Source:Xenbase;A...	[more]

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2


Match Name	E-value	Identity	Description
Ntrk3	6.500e-6	23.01	neurotrophic tyrosine kinase, receptor, type 3 [So...	[more]
Ntrk3	9.654e-6	23.01	neurotrophic tyrosine kinase, receptor, type 3 [So...	[more]

BLAST of negative regulator of reactive oxygen species-like vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 2


Match Name	E-value	Identity	Description
sp\|A4IGL7\|PXDN_XENTR	2.125e-10	24.08	Peroxidasin OS=Xenopus tropicalis OX=8364 GN=pxdn ...	[more]
sp\|Q6AXL3\|LRC33_DANRE	2.968e-6	33.04	Transforming growth factor beta activator LRRC33 O...	[more]

BLAST of negative regulator of reactive oxygen species-like vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
R7TAS3	1.120e-13	21.60	Ig-like domain-containing protein (Fragment) OS=Ca...	[more]
I1ZII9	4.988e-13	23.34	Leucine rich repeat and fibronectin type III domai...	[more]
T1DF80	5.513e-12	25.44	LRFN-1 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1	[more]
A0A267GSH0	9.710e-12	27.11	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A267G4B5	2.152e-11	27.41	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3


Match Name	E-value	Identity	Description
ENSAMXT00000018470.2	2.565e-6	37.84	pep primary_assembly:Astyanax_mexicanus-2.0:3:5465...	[more]
flrt3	5.752e-6	23.72	fibronectin leucine rich transmembrane protein 3 [...	[more]
nrros	5.970e-6	38.04	negative regulator of reactive oxygen species [Sou...	[more]

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
pxdn	3.585e-11	23.50	peroxidasin [Source:ZFIN;Acc:ZDB-GENE-140415-2]	[more]

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of negative regulator of reactive oxygen species-like vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pxdn	1.433e-11	25.31	peroxidasin [Source:NCBI gene;Acc:101162089]	[more]
pxdn	1.233e-10	24.90	peroxidasin [Source:NCBI gene;Acc:101162089]	[more]
pxdn	8.436e-9	24.88	peroxidasin [Source:NCBI gene;Acc:101162089]	[more]
lrfn1	1.352e-6	22.99	leucine rich repeat and fibronectin type III domai...	[more]
lrrtm4l1	1.899e-6	25.48	leucine-rich repeat transmembrane neuronal protein...	[more]

BLAST of negative regulator of reactive oxygen species-like vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000080200.1	0.000e+0	99.64	SMESG000080200.1	[more]
SMESG000080200.1	0.000e+0	100.00	SMESG000080200.1	[more]
SMESG000080200.1	0.000e+0	99.39	SMESG000080200.1	[more]
SMESG000051501.1	5.111e-31	27.55	SMESG000051501.1	[more]
SMESG000051501.1	4.246e-29	28.00	SMESG000051501.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30020478 ID=SMED30020478|Name=negative regulator of reactive oxygen species-like|organism=Schmidtea mediterranea sexual|type=transcript|length=1711bp
TTAGGATTGGTCAGTGCAGAAGTCACTGATAATGATAATAATAAGTGACA
GGATTATTAATTATAATTTTGTCGTTGACGAAATATTCTTGATTGAAATG
TGGATTTACTTGTTGATAGGAGCAATCTCTGTCGTAACAACGGATCAAGA
GGGATTGGTGTGCAATCGGCAAAATTTCAACAATAAACCAGAATCTCATT
GTTCTGATATACCATCGAAGGAAGAATGGGAAAGGATTAAGAACACTACG
ATACAGACAATAAGATGCAAACATTCGAACAAGTCAAACAGCCTATCAGA
TATTCGAATGAAAAATCTCCAACGATTGGTCTATATCTATATTGGAGATT
GTAATGTTCAGAGCTTGCCAATGAATTTTTTCGAGGATTTAACACAACTA
GAAACGGTATATTTAGACAACTTACCAATAGAAATCCTAAAAGAGAATAC
ATTCAAAAATTCATCGAATATCATTGAACTGATATTATCTGGTTTGGGAT
CTTTGAAAAGGATCCACCCAAGATTTCTCGGTGATCAAAATAAATTAGCA
ACTTTAACTCTGACTAAATCAAATATCGATCCAACACAACTGAGACCTAC
CCTGCTGACAGTATATAACACTCTGGCGAAATTCTATTGGCGGAGAAATG
TGCAAAACCTTATAATTGGGAAAGATTACTTTCAGCCTTTTAATTTCGAA
AGTGTGATCTTGGAATATAACGGAATCACAAATACTGACTTTCTAGAGTT
GCTCAATACGAAAGAACTCTCATTAAAAGGCAATCCAATTGGGATAAAGG
AGAAATTGAATTGGAAAAATTACAGAAAGTTATCGAAGAGTCTAAAAAAA
CTCGATCTATCGGAAACCGGTCTCGATCTAAGGCCGGATATGAAATTTCC
TAAACTCGAGGAATTGGCGCTGAGTTCAAACGGAATACACCAGATACCGA
GCCATGTCGAAAAATTTCTCCCAAATCTCCAATTGTTAGACATTCGCAAT
AACAAATTGACGACTTTACCAAGTCTCGACTACATGCTCAGATACAAATT
CGGAAAGGTCTATTTGCAGGGCAACATTTTCAATTGCAACTGTGAAATGA
TTTGGATACGGTCGATTGAAGCGGACAGGATTAAGGGTTTAAAATGCGAT
AATGTGAATTTTGAAAAACATGTTAAAAACCAAGAGTTAACAAGAAGTCG
CATTCTAAAATCGAAGATGATTTGCACAGAGCCATTGTTAAAATTACAGT
TAAGTGATCAGTTCAAGTCATATGATTACACGATTTCTGTGGTCAGCGAC
ACGTTACAGATCTACAAATTCGATCTGTATCCCAACCATTTGATTTCATG
GCAATGCATCGGAGAAGGAAATCCAGCGCCGAGATTGAAGTGGATCAAGA
ATCAACAAACCCTAAAAATCGAGAATCCCCCGTTAGACAGGCTTAATAAC
AAAACGGTCATGAAAAATCTTATAATTCCCGATGATATTAAAACAGCAGA
TAATGAAACCTATGTTTGCAGAGCCAAATCAATAGCTGGTATTTCGGAGA
TTCGTTTGGAAGTAACAAAAAAATATTCAAAAAATCCAATGCCAGCACTT
GGACAAATAGATTTACAGAACTTTGCTACCGAAAATTCAAAGCCTTCATT
TTTAAATTTATTTTTATTAATGATAATAAATGCTTTTATTCGTTAATAAC
TGTTAGAATGC

protein sequence of SMED30020478-orf-1

>SMED30020478-orf-1 ID=SMED30020478-orf-1|Name=SMED30020478-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=555bp
MIIISDRIINYNFVVDEIFLIEMWIYLLIGAISVVTTDQEGLVCNRQNFN
NKPESHCSDIPSKEEWERIKNTTIQTIRCKHSNKSNSLSDIRMKNLQRLV
YIYIGDCNVQSLPMNFFEDLTQLETVYLDNLPIEILKENTFKNSSNIIEL
ILSGLGSLKRIHPRFLGDQNKLATLTLTKSNIDPTQLRPTLLTVYNTLAK
FYWRRNVQNLIIGKDYFQPFNFESVILEYNGITNTDFLELLNTKELSLKG
NPIGIKEKLNWKNYRKLSKSLKKLDLSETGLDLRPDMKFPKLEELALSSN
GIHQIPSHVEKFLPNLQLLDIRNNKLTTLPSLDYMLRYKFGKVYLQGNIF
NCNCEMIWIRSIEADRIKGLKCDNVNFEKHVKNQELTRSRILKSKMICTE
PLLKLQLSDQFKSYDYTISVVSDTLQIYKFDLYPNHLISWQCIGEGNPAP
RLKWIKNQQTLKIENPPLDRLNNKTVMKNLIIPDDIKTADNETYVCRAKS
IAGISEIRLEVTKKYSKNPMPALGQIDLQNFATENSKPSFLNLFLLMIIN
AFIR*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000099	neuron
PLANA:0000101	muscle cell

Vocabulary: **INTERPRO**
Term	Definition
IPR003591	Leu-rich_rpt_typical-subtyp
IPR013783	Ig-like_fold
IPR001611	Leu-rich_rpt
IPR032675	LRR_dom_sf
IPR007110	Ig-like_dom

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding
GO:0004860	protein kinase inhibitor activity

Vocabulary: **cellular component**
Term	Definition
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030054	cell junction
GO:0045202	synapse
GO:0045211	postsynaptic membrane
GO:0005737	cytoplasm

Vocabulary: **biological process**
Term	Definition
GO:0006469	negative regulation of protein kinase activity
GO:0019221	cytokine-mediated signaling pathway
GO:0046426	negative regulation of JAK-STAT cascade

Main menu

negative regulator of reactive oxygen species-like

Zeng et. al., 2018

▻ Overview

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Owlery

blazegraph-runner