low-density lipoprotein receptor-related protein 2

Overview


Name	low-density lipoprotein receptor-related protein 2
Smed ID	SMED30020449
Length (bp)	2153

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of low-density lipoprotein receptor-related protein 2 (SMED30020449) t-SNE clustered cells

Violin plots show distribution of expression levels for low-density lipoprotein receptor-related protein 2 (SMED30020449) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of low-density lipoprotein receptor-related protein 2 (SMED30020449) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30020449

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 9

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
protonephridia	SMED30020449	SMESG000062507.1	dd_Smed_v4_1510_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30020449	SMESG000062507.1	dd_Smed_v4_1510_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30020449	SMESG000062507.1	dd_Smed_v4_1510_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020449	SMESG000062507.1	Contig39710	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020449	SMESG000062507.1	Contig39710	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020449	SMESG000062507.1 SMESG000023090.1 SMESG000023089.1	Contig50217	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020449	SMESG000062507.1 SMESG000023090.1 SMESG000023089.1	Contig50217	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30020449	SMESG000062507.1	dd_Smed_v6_1510_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
epidermis	SMED30020449	SMESG000062507.1	dd_Smed_v4_1510_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Human
Match: VLDLR (very low density lipoprotein receptor [Source:HGNC Symbol;Acc:HGNC:12698])

HSP 1 Score: 196.823 bits (499), Expect = 2.174e-52
Identity = 142/492 (28.86%), Postives = 223/492 (45.33%), Query Frame = 1

Query:  100 HFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTE--HDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDL-----YLSSISNK--QNIEM--NLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLS-QLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            H KC   +  CG     +CI K W CD + DC D SDEVNCP   C  +QF+C D   CI   + C+G+ DC++  DE NC N+N C     + C   +  ECI I  +CN   +C    D  L+ C  + C  +   CSHIC +    + CDC    EL  D + C  I++C +NP +C Q C +    Y C C  GY        C    +E  +                          IF  + DI    + L R E +     +     L            DL     + +SI +K  ++++M  N+ N +A   A+D     +++TD    +I V  L    +  + + D   P +I +DP+ G ++W D G      KI+ A M+G  +  L+  +I+ P  + +D+ + RLYW D     +  +D+N    ++ +K+   LA    HP ++ IF +R+YW D +   +Y A+K TG ++  +
Sbjct:  236 HTKCPASEIQCGSG---ECIHKKWRCDGDPDCKDGSDEVNCPSRTCRPDQFECEDGS-CIHGSRQCNGIRDCVDGSDEVNCKNVNQCLGPGKFKC---RSGECIDISKVCNQEQDCRDWSDEPLKECHINECLVNNGGCSHICKDLVIGYECDCAAGFELI-DRKTCGDIDEC-QNPGICSQICINLKGGYKCECSRGYQMDLATGVCKAVGKEPSL--------------------------IFTNRRDIRK--IGLERKEYIQLVEQLRNTVALDADIAAQKLFWADLSQKAIFSASIDDKVGRHVKMIDNVYNPAAI--AVDWVYKTIYWTDAASKTISVATLDGTKRKFLFNSDLREPASIAVDPLSGFVYWSDWGEP---AKIEKAGMNGFDRRPLVTADIQWPNGITLDLIKSRLYWLDSKLHMLSSVDLNGQDRRIVLKSLEFLA----HPLALTIFEDRVYWIDGENEAVYGANKFTGSELATL 681

HSP 2 Score: 62.3882 bits (150), Expect = 2.759e-9
Identity = 50/154 (32.47%), Postives = 75/154 (48.70%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKT----HYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHI-CINKYSSFTCDCPPDMELSEDNRNC 597
            +CI+ LW CD ++DC D SDE NC    C ++ F C ++  C+P    CDG  DC +  DE    +   C+ +T      +CG     +CI +   C+   +C + +D  ENC    C   E TCS   CI++  +F C+   D     D  +C
Sbjct:   44 RCITLLWKCDGDEDCVDGSDEKNCVKKTCAESDFVC-NNGQCVPSRWKCDGDPDCEDGSDE----SPEQCHMRTCRIHEISCG-AHSTQCIPVSWRCDGENDCDSGEDE-ENCGNITCSPDEFTCSSGRCISR--NFVCNGQDDCSDGSDELDC 188

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Human
Match: VLDLR (very low density lipoprotein receptor [Source:HGNC Symbol;Acc:HGNC:12698])

HSP 1 Score: 196.052 bits (497), Expect = 3.026e-52
Identity = 142/492 (28.86%), Postives = 223/492 (45.33%), Query Frame = 1

Query:  100 HFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTE--HDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDL-----YLSSISNK--QNIEM--NLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLS-QLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            H KC   +  CG     +CI K W CD + DC D SDEVNCP   C  +QF+C D   CI   + C+G+ DC++  DE NC N+N C     + C   +  ECI I  +CN   +C    D  L+ C  + C  +   CSHIC +    + CDC    EL  D + C  I++C +NP +C Q C +    Y C C  GY        C    +E  +                          IF  + DI    + L R E +     +     L            DL     + +SI +K  ++++M  N+ N +A   A+D     +++TD    +I V  L    +  + + D   P +I +DP+ G ++W D G      KI+ A M+G  +  L+  +I+ P  + +D+ + RLYW D     +  +D+N    ++ +K+   LA    HP ++ IF +R+YW D +   +Y A+K TG ++  +
Sbjct:  236 HTKCPASEIQCGSG---ECIHKKWRCDGDPDCKDGSDEVNCPSRTCRPDQFECEDGS-CIHGSRQCNGIRDCVDGSDEVNCKNVNQCLGPGKFKC---RSGECIDISKVCNQEQDCRDWSDEPLKECHINECLVNNGGCSHICKDLVIGYECDCAAGFELI-DRKTCGDIDEC-QNPGICSQICINLKGGYKCECSRGYQMDLATGVCKAVGKEPSL--------------------------IFTNRRDIRK--IGLERKEYIQLVEQLRNTVALDADIAAQKLFWADLSQKAIFSASIDDKVGRHVKMIDNVYNPAAI--AVDWVYKTIYWTDAASKTISVATLDGTKRKFLFNSDLREPASIAVDPLSGFVYWSDWGEP---AKIEKAGMNGFDRRPLVTADIQWPNGITLDLIKSRLYWLDSKLHMLSSVDLNGQDRRIVLKSLEFLA----HPLALTIFEDRVYWIDGENEAVYGANKFTGSELATL 681

HSP 2 Score: 62.003 bits (149), Expect = 3.373e-9
Identity = 50/154 (32.47%), Postives = 75/154 (48.70%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKT----HYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHI-CINKYSSFTCDCPPDMELSEDNRNC 597
            +CI+ LW CD ++DC D SDE NC    C ++ F C ++  C+P    CDG  DC +  DE    +   C+ +T      +CG     +CI +   C+   +C + +D  ENC    C   E TCS   CI++  +F C+   D     D  +C
Sbjct:   44 RCITLLWKCDGDEDCVDGSDEKNCVKKTCAESDFVC-NNGQCVPSRWKCDGDPDCEDGSDE----SPEQCHMRTCRIHEISCG-AHSTQCIPVSWRCDGENDCDSGEDE-ENCGNITCSPDEFTCSSGRCISR--NFVCNGQDDCSDGSDELDC 188

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BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Human
Match: LDLR (low density lipoprotein receptor [Source:HGNC Symbol;Acc:HGNC:6547])

HSP 1 Score: 189.504 bits (480), Expect = 1.233e-50
Identity = 153/613 (24.96%), Postives = 264/613 (43.07%), Query Frame = 1

Query:  109 CLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLD------VNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFST---------------ALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI-DKRVKPINLRII-----SKESNRQLIKKINEHKIGKYCSGVINTCRGSCLPNHDMPEMPKCF-GIPRIE-----------------EKIRSKNQSLWLILIPVVILGFVCIVLF 1809
            C   D  CG     +CI + W CD   DCD+ SDE  CP   C  ++F+C D + CI   + CD   DC +  DE  C N+  C     + C +    ECI ++ +CN   +C    D  ++ C  + C  +   CSH+C +    + C CP   +L    R C+ I++C ++P+ C Q C +    Y C C +G+                                 L+PH KA +       +F  +      + L+R+E   Y+SL+   N+  V  L     +  +Y S +S +      L      S+               A+D   + +++TD    ++ V +     +  +  ++   P  IV+DPV G ++W D G      KIK   ++G   Y+L+ + I+ P  + +D+   RLYW D    +I  ID+N     N KT         HPFS+ +F ++++W+D+    I+SA+++TG DV ++ +  + P ++ +       +E+   +  +       K  S  + T   +  P  D   +P    G+  +E                 EK  S  ++L ++L P+V+L F+C+ +F
Sbjct:   68 CKSGDFSCG-GRVNRCIPQFWRCDGQVDCDNGSDEQGCPVATCRPDEFQCSDGN-CIHGSRQCDREYDCKDMSDEVGCVNVTLCEGPNKFKCHSG---ECITLDKVCNMARDCRDWSDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVA-QRRCEDIDEC-QDPDTCSQLCVNLEGGYKCQCEEGF--------------------------------QLDPHTKACKAVGSIAYLFFTNRHEVRKMTLDRSE---YTSLI--PNLRNVVALDTEVASNRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWTDWGTP---AKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGG---NRKTILEDEKRLAHPFSLAVFEDKVFWTDIINEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQPREAEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGATPGLTTVEIVTMSHQALGDVAGRGNEKKPSSVRALSIVL-PIVLLVFLCLGVF 629

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Human
Match: LRP4 (LDL receptor related protein 4 [Source:HGNC Symbol;Acc:HGNC:6696])

HSP 1 Score: 180.259 bits (456), Expect = 2.241e-46
Identity = 130/484 (26.86%), Postives = 221/484 (45.66%), Query Frame = 1

Query:  154 CISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCN-EKTHYNCGNTKKLECIKIEDICNTNINCSTNKDS--LENCKA----DFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQ-DDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIE--MNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKRVK-PINLRII 1572
            CI+  W CD + DCDD SDE NC   +C   QF+C  S  C+     CDG +DC +N DE NC N  S       + C N +   CI    +CN   +C  N D    +NC+     + C  +   C+  C     +  C C     L+ED   C+ +N+C +    C QGC ++  ++ C+C  GY     +  P     +             + I  + PH     +     ++  +LD + +R E+VF+S +                  +D  L +  N  N+E  ++    S    A+D   + L++TD   S I V NL    +  ++ ++   P  I + P+ G ++W D GN    P+I+ ++MDGS +  + +  +  P  L ID   +R+YW D     I+  +++   +      +V++    HPF+I +F + +YW+D     I SA+K TGK+ ++I  ++  P+++  +
Sbjct:  243 CINAGWRCDGDADCDDQSDERNCTTSMCTAEQFRC-HSGRCVRLSWRCDGEDDCADNSDEENCENTGSPQCALDQFLCWNGR---CIGQRKLCNGVNDCGDNSDESPQQNCRPRTGEENCNVNNGGCAQKCQMVRGAVQCTCHTGYRLTEDGHTCQDVNECAEE-GYCSQGCTNSEGAFQCWCETGY-----ELRPDRRSCKALGPEPVLLFANRIDIRQVLPHRSEYTLLLNNLENAIALDFH-HRRELVFWSDVT-----------------LDRILRANLNGSNVEEVVSTGLESPGGLAVDWVHDKLYWTDSGTSRIEVANLDGAHRKVLLWQNLEKPRAIALHPMEGTIYWTDWGNT---PRIEASSMDGSGRRIIADTHLFWPNGLTIDYAGRRMYWVDAKHHVIERANLDGSHRK-----AVISQGLPHPFAITVFEDSLYWTDWHTKSINSANKFTGKNQEIIRNKLHFPMDIHTL 690

HSP 2 Score: 106.686 bits (265), Expect = 7.517e-23
Identity = 56/192 (29.17%), Postives = 95/192 (49.48%), Query Frame = 1

Query:  976 SNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKRVK 1551
               Q + ++    S    A+D   N L++TD     I V N     +  ++ ++   P +IV++P+ G ++W D G     PKI+ A MD S +  ++   +  P  LAID   QRLYW D   + +K I+   L     K    +  +  HPF + ++G RIYW+D +   I SA ++TG D + + + ++
Sbjct:  804 GTGQEVVVDTSLESPAGLAIDWVTNKLYWTDAGTDRIEVANTDGSMRTVLIWENLDRPRDIVVEPMGGYMYWTDWGAS---PKIERAGMDASGRQVIISSNLTWPNGLAIDYGSQRLYWAD---AGMKTIEFAGLDGSKRKVL--IGSQLPHPFGLTLYGERIYWTDWQTKSIQSADRLTGLDRETLQENLE 987

HSP 3 Score: 88.1965 bits (217), Expect = 3.256e-17
Identity = 87/368 (23.64%), Postives = 150/368 (40.76%), Query Frame = 1

Query:  490 CKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKRVKPINLRIISKESNRQ 1593
            C +    CSH+C+ + S F+C CP  ++L  D +       C  +PE           +Y  F   G     +  + T++  ++                    H    E+    +++ SLD + + +  V+Y+     D  L V +        DL  S++     I   LK       A+D     L++TD   ++I    L    +  +++     P  I + P  G LFW D G+     KI+ AN+DGS +  L+  ++  P  L +D + +R+YW D     I+  D+N       K   VL     HPF++      IYW+D +   I    K +G++ + +   V+ + + II     RQ
Sbjct: 1313 CGSRNGGCSHLCLPRPSGFSCACPTGIQLKGDGKT------CDPSPE-----------TYLLFSSRGSIR--RISLDTSDHTDV--------------------HVPVPEL----NNVISLDYD-SVDGKVYYT-----DVFLDVIR------RADLNGSNMETV--IGRGLKTTDGL--AVDWVARNLYWTDTGRNTIEASRLDGSCRKVLINNSLDEPRAIAVFPRKGYLFWTDWGHI---AKIERANLDGSERKVLINTDLGWPNGLTLDYDTRRIYWVDAHLDRIESADLNG------KLRQVLVSHVSHPFALTQQDRWIYWTDWQTKSIQRVDKYSGRNKETVLANVEGL-MDIIVVSPQRQ 1611

HSP 4 Score: 78.1814 bits (191), Expect = 4.084e-14
Identity = 47/169 (27.81%), Postives = 81/169 (47.93%), Query Frame = 1

Query: 1030 ALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            A+D     +++TD   + I V NL    +  +V ++   P  IV+   MG ++W D G EN   K++ + MDGS +  L+   +  P  L +D    +L W D     I+  D+N  ++        L     HP+ + +  + IYW+D +   I+ A K TG +V ++
Sbjct: 1130 AVDAIGRKVYWTDTGTNRIEVGNLDGSMRKVLVWQNLDSPRAIVLYHEMGFMYWTDWG-EN--AKLERSGMDGSDRAVLINNNLGWPNGLTVDKASSQLLWADAHTERIEAADLNGANR------HTLVSPVQHPYGLTLLDSYIYWTDWQTRSIHRADKGTGSNVILV 1289

HSP 5 Score: 68.5514 bits (166), Expect = 4.002e-11
Identity = 64/234 (27.35%), Postives = 93/234 (39.74%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADF--------------------------------------------CKTSENTC-SHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQG--------------CQDNGKSYNC 675
            +CI + WVCD + DC+D+SDE +CPP  C++++F C +   CI     CDG NDC +N DE  C ++  C++K  + C +     CI     C+ + +C    D  ENC +                                              C++ E  C S +CIN  + + CD   D +   D RNC   + C      CH G              C DN    NC
Sbjct:   82 KCIRRSWVCDGDNDCEDDSDEQDCPPRECEEDEFPCQNG-YCIRSLWHCDGDNDCGDNSDE-QC-DMRKCSDK-EFRCSDGS---CIAEHWYCDGDTDCKDGSDE-ENCPSAVPAPPCNLEEFQCAYGRCILDIYHCDGDDDCGDWSDESDCSSHQPCRSGEFMCDSGLCIN--AGWRCDGDADCDDQSDERNCT-TSMCTAEQFRCHSGRCVRLSWRCDGEDDCADNSDEENC 304

HSP 6 Score: 62.3882 bits (150), Expect = 3.232e-9
Identity = 55/166 (33.13%), Postives = 74/166 (44.58%), Query Frame = 1

Query:  130 CGKNSFF---------QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCS-HICINKYSSFTCDCPPDMELSEDNRNC 597
            CG++ F           CI   W CD + DC D+SDE  C    C    F C D+  CI R  +CDG NDC ++ DE +C     C E+  + C N     CI+    C+ + +C  N D  E C    C   E  CS   CI ++  + CD   D +   D  NC
Sbjct:   27 CGRSHFTCAVSALGECTCIPAQWQCDGDNDCGDHSDEDGCILPTCSPLDFHC-DNGKCIRRSWVCDGDNDCEDDSDEQDCPP-REC-EEDEFPCQNGY---CIRSLWHCDGDNDCGDNSD--EQCDMRKCSDKEFRCSDGSCIAEH--WYCDGDTDCKDGSDEENC 182

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Human
Match: LDLR (low density lipoprotein receptor [Source:HGNC Symbol;Acc:HGNC:6547])

HSP 1 Score: 176.407 bits (446), Expect = 1.253e-45
Identity = 128/484 (26.45%), Postives = 214/484 (44.21%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLD------VNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFST---------------ALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            +CI   W CD   DC D SDE NC    C  ++F+C D + CI   + CD   DC +  DE  C N+  C     + C +    ECI ++ +CN   +C    D  ++ C  + C  +   CSH+C +    + C CP   +L    R C+ I++C ++P+ C Q C +    Y C C +G+                                 L+PH KA +       +F  +      + L+R+E   Y+SL+   N+  V  L     +  +Y S +S +      L      S+               A+D   + +++TD    ++ V +     +  +  ++   P  IV+DPV G ++W D G      KIK   ++G   Y+L+ + I+ P  + +D+   RLYW D    +I  ID+N     N KT         HPFS+ +F ++++W+D+    I+SA+++TG DV ++
Sbjct:  167 ECIHSSWRCDGGPDCKDKSDEENCAVATCRPDEFQCSDGN-CIHGSRQCDREYDCKDMSDEVGCVNVTLCEGPNKFKCHSG---ECITLDKVCNMARDCRDWSDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVA-QRRCEDIDEC-QDPDTCSQLCVNLEGGYKCQCEEGF--------------------------------QLDPHTKACKAVGSIAYLFFTNRHEVRKMTLDRSE---YTSLI--PNLRNVVALDTEVASNRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWTDWGTP---AKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGG---NRKTILEDEKRLAHPFSLAVFEDKVFWTDIINEAIFSANRLTGSDVNLL 601

HSP 2 Score: 65.0846 bits (157), Expect = 3.406e-10
Identity = 57/188 (30.32%), Postives = 87/188 (46.28%), Query Frame = 1

Query:  130 CGKNSF----FQCISKLWVCDYNQDCDDNSDEV--NCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSL-ENCKADF--------CKTSENTC-SHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQG 645
            C +N F     +CIS  WVCD + +C D SDE    C P  C +++F+C D   CI R+ +CD   DC++  DE +C  + +C   + + C ++    CI     C+ + +C    D   + C+  +        C   E  C S  CI  +SS+ CD  PD +   D  NC  +  C  +   C  G
Sbjct:   27 CERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCSPKTCSQDEFRCHDGK-CISRQFVCDSDRDCLDGSDEASCP-VLTCGPAS-FQCNSST---CIPQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECI--HSSWRCDGGPDCKDKSDEENCA-VATCRPDEFQCSDG 205

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Celegans
Match: lrp-1 (Low-density lipoprotein receptor-related protein [Source:UniProtKB/Swiss-Prot;Acc:Q04833])

HSP 1 Score: 150.214 bits (378), Expect = 5.299e-37
Identity = 139/517 (26.89%), Postives = 220/517 (42.55%), Query Frame = 1

Query:  109 CLQDDHYCGKNSFF----QCISKLWVCDYNQDCDDNSDE-VNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTK----KLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENT-CSHICINKYSSFTCDCPPDMELS-EDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGY--TEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHY---------KAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTS-FDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQ-----YTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKRVK-PINLRII 1572
            C  +   C K  F      CI   W CD + DC D SDE  NC    C  + F+C +   C+P    CDG +DC +  DE +C   NS + +    C N +      ECI    +C+ N +C+   D    C  D C  +E   C   C++    + CDC     +   D ++C ++N+C++    C Q C D   SY C C DGY  +  D  C  T  E E                   N HY         K +   +G D++ SLD++L             K  ++   KL+   +++D   S +S+ + + +          A+D     L+  +  + SI V  L   F K  I D+    P  IV+ P  G LF+ +   +   P I    +DGS +     + L E ++  P  +AID    RL+W D   + I ++D +   + +I      A    H  S+ +F + +YW+D    ++    K TGK+  ++ K V+ P +LRI+
Sbjct: 3093 CKTEKKECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSCQPDFFQCANHK-CVPNSWKCDGNDDCEDGSDEKDCPK-NSASAQKASKCSNGQFQCTSGECIDDAKVCDRNFDCTDRSDESSLCFIDECSLAEKPLCEQKCMDMKIGYKCDCFEGFAIDISDQKSCHNVNECYEGISGCSQKCDDKIGSYKCGCVDGYQLSSDDHSCKRTEMEPE-------------PFFLLANKHYIRKISIDGNKYELAAQGFDNVVSLDIDLTEK----------KAYLIDQGKLRLLRVDLDEMDSPLSSYETV-LRHNVYGTEGIAVDWVGRKLYMLNRQERSIRVCELDGRFCKTLIRDR-IQQPKAIVVHPGKGYLFFTEWSLQ---PYIGRIALDGSPELQDPIFKLAEHDLGWPNAIAIDYFSDRLFWGDAHLNEIGFMDFDGNGRRHIP-----AQRTSHVSSMVVFDDYLYWADWNLREVLRCDKWTGKNETILKKTVQLPNDLRIV 3574

HSP 2 Score: 126.716 bits (317), Expect = 1.677e-29
Identity = 124/478 (25.94%), Postives = 198/478 (41.42%), Query Frame = 1

Query:  154 CISKLWVCDYNQDCDDNSDE--VNCPP-MICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWN------CTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHK-DN------VLQVSKLQNW-PLNVDLYLSSISNKQNIEMNLKNLSAF-----------STALDPARNLLFFTDYNDSSIYVMNLTS-FDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYF--HPFSIFIFGNRIYWSDLKEHKI 1494
            CI   W CD  QDCDD SDE    C     C  +QFKC +   CI    LCDG NDC +  DE +        N   C  + H  C N ++  CI +  +C+   +C    D    C  D C      CS  C N  +   C CP   +L    + C+  N+C  +   C Q C+D    + C C +GY            E +++                       K   +  D++    + ++    ++YS   HK DN      +++ +    W  L   +Y S I  K+ +  N    +A              ALD     L++ D + ++I V NL     +  +V ++   P  I +DP  G +FW D G     P I+ A+MDG+ +  +++ +I  P  +A+D    R+Y+ D     I +++ +   +       VLA   F  HP ++ IF + +Y+SD +  K+
Sbjct: 1283 CIPASWKCDGQQDCDDGSDEPKFGCTSGRQCSSDQFKCGNG-RCILNNWLCDGENDCGDGSDESSERGCKTSMNARKCPFE-HVACENDQET-CIPLHQLCDGKTHCPGGTDEGGRCARDLCSADRAGCSFKCHNSPNGPICSCPFGEQLVNKTK-CEPENECL-DSSSCSQRCKDEKHGFTCSCDEGY------------ELDVD-----------------------KRTCKVADNVKDTRIYVSNRNRIYYSD--HKLDNWHTFGAIVENAIALAWDSLTDRIYWSDIREKKILSANRNGTNATVFIADGLDITEGIALDWVGRNLYWVDSSLNTIEVANLEDPKQRTLLVHQNVSQPRGIAVDPRKGVMFWTDWGQN---PCIERASMDGTDRQIIVKTKIYWPNTIALDYTTDRVYFADSKLDFIDFVNYDGSGRTQ-----VLASSKFVQHPHALAIFEDMMYYSDRRLQKL 1710

HSP 3 Score: 99.3673 bits (246), Expect = 5.952e-21
Identity = 112/500 (22.40%), Postives = 187/500 (37.40%), Query Frame = 1

Query:   97 CHFK-CLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTN--------INSCNEKTHYN---CGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSE-NTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHK------DNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYF-HPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            C FK C  ++  C KN   +C  + + CDY  DC DNSDE  C    C   ++ CP +  CI + KLCDG  DC +  DE  C+            C+   H     C +  KL+                  D      +D  + +E   C  +C N    FTC C               +  CF   ++ H   +DN          GY      CV     N   +            +   NP  + K++  G+  I+ +D +    ++ +   L H       D+  ++S+++   L   +Y   +                  A+D   N L+  +     I V +     +  ++      P +I +DP+ G +F+       N  K++ A MDG+ + TL+     +   + +DI  +R+YW D     ++ ID     Q N +      +    HPF + +F   +YW+D     +    K  G D K++
Sbjct:  218 CEFKKCTANEFQC-KNK--RCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLGCQAGCHPSPHGGECTCPSGYKLD------------------DRFHRTCSDINECAEFGYCDQLCANHRPGFTCSC---------------LGDCF-TLQMEHGPGKDN------LTMRGY------CV---SNNADKMKLFVARREGLYRLNPKNPDEEVKKLASGE-FIYGIDFDYGDRKIFWTDRLAHSAFSADVDDEGEISQIKKLSLKSLVYPRCL------------------AVDWITNTLYIIESGSRRIDVSSYDGERRTVLLADGLTLPLDIALDPLRGEMFFT------NQLKLEAAAMDGTNRRTLVNTHTHQVSGIVVDITAKRVYWVDPKVDRLESIDY----QGNDRRIVAQGMNVVPHPFGLALFDQYLYWTDWTRLGVIQVEKF-GSDTKLL 635

HSP 4 Score: 95.5153 bits (236), Expect = 7.700e-20
Identity = 136/584 (23.29%), Postives = 226/584 (38.70%), Query Frame = 1

Query:  154 CISKLWVCDYNQDCDDNSDEVN--CPPMICDKN-QFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYN--------CGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTS------ENTCSHICINKYSSFTCDCP----PDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEH-------DQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVN--------LNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDL-YLSSISNKQNIEMNLKNL--SAFS----TALDPARNLLF---FTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAID-IEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKIT-------------GKDVKVIDKRVKPINLRIISKESNRQLIKKINEHKIGKYC---SGVINTCRGSCLPNH----DMPEMPKC 1704
            CI + ++CD + DC DNSDE +  C    CD   +F+C  S LC+   +LC+G NDC  N+  ++  +++ C+  + Y         C N K   C+     C+   +C    D +  C     KTS         C HIC +    F C C     PD    +  + C  I++C  N   C Q C +   SY C C++ Y  +        + C    +   + +         S+     N H  AK      +DI  +  +        ++ +E   Y S +   N       +   L+VD   +  +     ++    NL  +A S      L  AR         + N   I+V         KIV      P  ++  P  GR+ + D G      KI+ A+MDG+ +  +++  +  P  +AID  +  R+YW D      KY  +++++    +  +V+   +  P+++ +F N IYW   +   +Y   K               G  V+V  K  K     +   E  +     ++    G  C    G++    GSC   H     MP+  KC
Sbjct: 3971 CIPRKFMCDGDNDCGDNSDETSSECRSAQCDPPLRFRCAHSRLCLNILQLCNGFNDCGPND--FSDEHLSMCSSFSEYGDCSSDQFKCANGK---CVNGTVACDRKDDCGDASDEI-GCSKHGGKTSCEAFGNNGGCKHICTDVRDGFYCHCRDGFRPD---PQSPKECIDIDECAGN-NTCTQLCLNTKGSYLCRCHEDYENNVVVGSMTGKDCRAKGDAANVMIGADDSLVQLSLHGSGTNRHAAAK-ANDDDNDIIGIAFDPRKELMYWIDGSERTIYRSAIANGN----QSHEGQKLDVDFAAMGVVPTAIAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLH---AKIECADMDGTHRQIIVKDLVFSPTSMAIDEGKGNRIYWVDP-----KYRRVDAVNIDGSERTTVVHDRHI-PYAVDVFENHIYWLSRESKTLYVQDKFGRGRVSVLASDLEDGHTVRVSQKYAKDTQRTVSGCERAQCSHLCVSLPSTGFACLCPDGIVPQLDGSCATQHVEALTMPKQCKC 4530

HSP 5 Score: 80.1073 bits (196), Expect = 4.274e-15
Identity = 116/536 (21.64%), Postives = 208/536 (38.81%), Query Frame = 1

Query:  106 KCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPM---ICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCT-NINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTN---KDSLENCKA----DFCKTSENTCSHI-CINKYSSFTCDCPPDMELSEDNRNC-KHINK----CFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIY---VMNLTSFDKIKIVDKD----CYFPFNIVIDPVMGRLFWIDLGN--ENNGPKIKMANM-----------------DGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTD-HFPSAIKYIDINSL-SQLNIKTFSVLAIEYFHPFSIFI---FGNRIYWSDLKEHKIYSAHKITGKDVKVIDKRVKPINLRI 1569
            +CL     C   +   CI++   CD  +DC + +DE++C  +    C   +F+C +S +CIPR+ +CDG NDC +N DE +       C+    + C +++   C+ I  +CN   +C  N    + L  C +      C + +  C++  C+N   +  CD   D   + D   C KH  K     F N   C   C D    + C C DG+    Q      + +E            + +   L  + K   + R  +D    + N+    M         D    +    +  + + L+ S  +     + N  +      A DP + L+++ D ++ +IY   + N     + + +D D       P  I +D   G LF   +    EN     +   M                 DG +   ++   +++P  L       R+ ++D    + I+  D++    Q+ +K         F P S+ I    GNRIYW D K  ++ + +    +   V+  R  P  + +
Sbjct: 3916 RCLPGHRQCDDGT---CIAEHKWCDRKKDCPNAADELHCEDVSRRTCSPFEFECANS-VCIPRKFMCDGDNDCGDNSDETSSECRSAQCDPPLRFRCAHSRL--CLNILQLCNGFNDCGPNDFSDEHLSMCSSFSEYGDCSSDQFKCANGKCVN--GTVACDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKHICTDVRDGFYCHCRDGFRPDPQSPKECIDIDEC---------AGNNTCTQLCLNTKGSYLCRCHED---YENNVVVGSMTGKDCRAKGDAANVMIGADDSLVQLSLHGSGTNRHAAAKANDDDNDIIGIAFDPRKELMYWIDGSERTIYRSAIANGNQSHEGQKLDVDFAAMGVVPTAIAVDYTTGNLFIAAVSENIENGLVTARKKRMSEPIDNQNTGFIFVCLPDGRYLKKIVAGHLQQPTALITAPSAGRICYSDAGLHAKIECADMDGTHRQIIVKDL------VFSPTSMAIDEGKGNRIYWVDPKYRRVDAVNIDGSERTTVVHDRHIPYAVDV 4425

HSP 6 Score: 74.3294 bits (181), Expect = 2.813e-13
Identity = 60/254 (23.62%), Postives = 112/254 (44.09%), Query Frame = 1

Query:  841 IFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNG----PKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVK-VIDKRVKPINLRIISKESN 1587
             F +DVNL R   V  S +    +   ++  +N  L         ++KQ     ++++S     LD     ++FT      +  ++        I   D  + + + IDP  G LFW D G + +G    P+I+ +N+ G  +  ++ + I  P  +A+D   Q++YW D     I+  D +  ++       V+A  Y    S+ I+   +Y SD   + ++   K +G  ++ V+  R  P  LR+ + ES+
Sbjct: 2480 TFDVDVNLRRVYFVVESPVGVNISWFSMNNAENPRLVFG------ASKQPHAKEIRHISDMK--LDWLTQKIYFTTGRGGKVMAIDTAGEHLSTIASGD--WTYALAIDPCSGLLFWSDSGYKTSGGLYEPRIERSNLAGGSRKVIVSESISLPAAIAVDFRNQKIYWADVNRLNIEVADYDGQNR------KVIASGY-RAKSLDIWDRWLYMSDPLSNGVFRIDKESGSGLENVVSDRRIPGALRVFASESD 2716

HSP 7 Score: 62.7734 bits (151), Expect = 9.069e-10
Identity = 40/182 (21.98%), Postives = 82/182 (45.05%), Query Frame = 1

Query:  964 LSSISNKQNIEMNLKNLSAFSTALDPARNLLFFT--DYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSA 1503
            +   S +  I  ++ +L+  S A+D     ++F   D   ++I V  L    +  ++      P +I +DPV   L+W D G +   P I+ + +DGS +  ++   I +P  L +D+  + +YW+D     I  +      +    T  ++  +      + + G  +YW+D +  K++ A
Sbjct: 2187 IGESSPRAVIRDSIGSLTIKSLAIDWINYNMYFINHDAERTNIEVSKLDGTYRKILLTTKTETPSSIAVDPVSRYLYWADQGQK---PTIQRSFLDGSRREVIVSSGIAEPTDLVVDVASKMIYWSDAKMDGIYRV------RSTGGTPELVRSDIASAAGVALHGQNMYWTDNRLEKLFRA 2359

HSP 8 Score: 61.6178 bits (148), Expect = 2.014e-9
Identity = 49/150 (32.67%), Postives = 69/150 (46.00%), Query Frame = 1

Query:  139 NSFFQCISKLWVCDYNQDCDDNSDE--VNCPPMICDK-NQFKCPDSDLCIPREKLCDGVNDCIENEDEWN--CTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKD----SLENCKADFCKTSENTCSHICINKYSSFTCDCP 561
            +S ++CI     C+   DC DNSDE    CP   CD   +F+C  S  CIPR  +CD  NDC +N DE +  C        ++ + C + K   CI    +C+  I CS   D    +L  C     +  + TC  I  +K+     DCP
Sbjct: 3801 SSSYRCIPNWAFCNGQDDCRDNSDEDKQRCP--TCDDVGEFRCATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCSESEFRCNDGK---CIPGSKVCDGTIQCSDGLDESQCTLRRCLPGHRQCDDGTC--IAEHKWCDRKKDCP 3943

HSP 9 Score: 56.6102 bits (135), Expect = 8.478e-8
Identity = 54/200 (27.00%), Postives = 86/200 (43.00%), Query Frame = 1

Query:  130 CGKNSF----FQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPD----SDLCIPREKLCDGVNDCIENEDEWNC-TNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADF--CKTSENTCSH--ICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVC-HQGCQDNGKSYNCFCYD 687
            C +N F     +CI   W CD + DC D  DE +CP   C  +Q++C      S  CI   + CD + DC +  DE +C  +   C+ +  + C + +  +C  +   C+   +C    D  ++C  +   C   +  C+    CI K  S+ CD   D     D  +     KC  N   C ++ CQ   + + C  YD
Sbjct:   53 CNENDFRCNDGKCIRTEWKCDGSGDCSDGEDEKDCPHPGCKSDQWQCDTYTWHSVSCIAEYQRCDNITDCADGSDEKDCPASTVDCSSQNVFMCADGR--QCFDVSKKCDGKYDCRDLSDEKDSCSRNHTACFQYQFRCADKTQCIQK--SWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQP--RKFRCDYYD 246

HSP 10 Score: 56.225 bits (134), Expect = 8.770e-8
Identity = 54/180 (30.00%), Postives = 73/180 (40.56%), Query Frame = 1

Query:  148 FQCISKLWVCDYNQDCDDNSDE---VNCPPMICDKNQFKCPDSDL-------CIPREKLCDGVNDCIENEDEWN--C-TNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCS-HICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQG 645
             +CIS+ ++CD   DC D SDE     C    C   +F C  +         CIPR  LCDG   C   EDE    C T    CN K  + C N     CI     C+ + +C    D   NC    C+     C+ H C+   +S+ CD   D E   D ++C   +   +    C  G
Sbjct: 3017 LKCISRAFICDGEDDCGDGSDEHSRHGCGNRTCTDQEFHCTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTELCKTEKKECN-KGEFRCSNQ---HCIHSTWECDGDNDCLDGSDEHANCTYSSCQPDFFQCANHKCVP--NSWKCDGNDDCEDGSDEKDCPKNSASAQKASKCSNG 3190

HSP 11 Score: 55.4546 bits (132), Expect = 1.772e-7
Identity = 33/94 (35.11%), Postives = 48/94 (51.06%), Query Frame = 1

Query:   70 FIICLNFYACHFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVN---CPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNC 342
            F++  +   C   C +    CG +   +CI KLW CD   DC D SDE     C   IC   +F+C + +   P + +CDG +DC ++ DE NC
Sbjct: 3614 FVLLSDQKTCEPNCTERQFACGGDDA-KCIPKLWYCDGEPDCRDGSDEPGESICGQRICPVGEFQCTNHNCTRPFQ-ICDGNDDCGDSSDEQNC 3705

HSP 12 Score: 51.9878 bits (123), Expect = 1.792e-6
Identity = 50/184 (27.17%), Postives = 72/184 (39.13%), Query Frame = 1

Query:  130 CGKNSF----FQCISKLWVCDYNQDCDDN--SDE--VNCP--PMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDE--------------------------WNCTNINSCN---EKTHYNCGNTKK--------------LECIKIEDICNTNINCSTNKD--SLENCKADFCKTSENTCS 516
            C + +F      CI++  VCD + DC D   SDE    CP  P+ C   + +CP++++CI    LCDG +DC +  DE                          W C   N C+   ++TH NC +T                L+CI    IC+   +C    D  S   C    C   E  C+
Sbjct: 2874 CAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDESLATCPGLPIDCRGVKVRCPNTNICIQPADLCDGYDDCGDKADENQLFCMNQQCAQHYVRCPSGRCIPETWQCDGDNDCSDGWDETHTNCTDTAGKKICVGDYLFQCDNLKCISRAFICDGEDDCGDGSDEHSRHGCGNRTCTDQEFHCT 3057

HSP 13 Score: 51.2174 bits (121), Expect = 3.298e-6
Identity = 40/134 (29.85%), Postives = 61/134 (45.52%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPP------MICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTK----KLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCSH 519
            +CI K W CD   DC D SDE++           C +N  KC ++  CIP +  CDG NDC +  DE    ++  C +     C   K       CI  +  C+++ +C    D  LE C    C  ++ +C++
Sbjct: 1067 RCIPKEWKCDGENDCLDESDEIDEKGDKCFHETECAENTIKCRNTKKCIPAQYGCDGDNDCGDYSDE----DVKYCKDGQKPVCAAKKFQCDNHRCIPEQWKCDSDNDCGDGSDEKLEMCGNATCAANQFSCAN 1196

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Celegans
Match: lrp-2 (Low-density lipoprotein RecePtor related [Source:UniProtKB/TrEMBL;Acc:O01768])

HSP 1 Score: 147.132 bits (370), Expect = 5.218e-36
Identity = 128/486 (26.34%), Postives = 214/486 (44.03%), Query Frame = 1

Query:  172 VCDYNQDCDDNSDEVNCPPM--ICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNT-------KKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHI--CINKYSSFTCDCPPDMELSE-DNRNCKHINKCFKNPEVCHQGCQDNGK-SYNCFCYDGY--TEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTS-FDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLE-KEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI--DKRVKPINLRII 1572
            +CD  QDC D  DE NC  +   C  N++ C DS  CI   +LCD   DC++  DEW    I S +E     C +          + C++ + +C+   +C +  D   +     C ++ N+C     C       +C C     LS  D + C     C K    C   C D     + CFC  GY  +E+ + C      N+           + + +F ++ H KA  +     +  +LD ++ ++++V+++ + H  N   ++ + N P           N   +  +L        A+D     +++TD N  +I V ++   F++I +       P  IV+DP+   +FW D G   +   I   NMDGS +  +L+ + I+ P  LA+D   QRLY+ D     I   + +       K   VL     H F++ +F + +YWSD   H I   HKITG + KV+  DK+ +P+  +I+
Sbjct: 2966 LCDGIQDCSDGFDEKNCASLDRQCKPNEWMC-DSGQCIDSGRLCDASVDCVDGSDEW--VEICSLSEPPRRGCPSGWSCLLTNGTIGCLQEQQLCDGRRDCMSGIDEQCDNPQGNCSSTRNSCDQTWNCQRHAGFESCSCDDGYHLSPYDKKTCLRSPSCPK--ANCSHFCIDRRDVGHQCFCAPGYILSENQKDC----RRNDTIEAEILMVYGHRLKLFTIDGHAKAT-LLSNLTNGVALDYDV-KSDLVYWTDVAHDGNKAGITSMSNQP-----------NTYRVINSLPTKGIDGIAVDWLGRNIYYTDRNHDAIAVCDMRGRFNRILLKGTPLNDPRAIVLDPLQALVFWTDWGASAH---IGRMNMDGSNEQVILQDRTIRWPNALAVDAPAQRLYFGDAHRDYIASCNYDGS-----KRRMVLRGSVRHIFALAVFEDYVYWSDWHNHTIERVHKITGTNRKVLIQDKQYRPMGFKIV 3421

HSP 2 Score: 116.316 bits (290), Expect = 3.242e-26
Identity = 127/584 (21.75%), Postives = 232/584 (39.73%), Query Frame = 1

Query:  130 CGKNSFF-----QCISKLWVCDYNQDCDDNSDEVNCPPMICDKN-QFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNIN------SCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGY--TEHDQKCVPT---------TEENEIXXXXXXXXXXXXXXXXXLNP-HYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLE----KEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNI-KTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDK-RVKPINLRIISKESNRQLIKKINEHKIGKYCSGVINTCRGSCLPNHDMPEMPKCFGIPRIEEKIRSKNQSLWLILIPVVILGF 1791
            CGK + F     +C+    +CD   DC    DE  CPP +CD      C +   CI ++  CDGV+DC +N DE +CT I        C +   Y C +    +CI  + +C+   +C    D    C  +     +  CSH C        C CP D  L ++   C   + C      C Q C  +G S+ C+C D +        C+           +  +EI ++ S +     +    +N      K    G   I+  D++ ++     Y+ LV +  +L    + ++ +                      +A   A+D     +++ D    +I V++     +  +++++     ++ ID   G +FW D   E + P+I+ A++ G+ +  + +     +   P  +A+D   +R+YW D    +I  I  +    + + +    L     H F I ++   +Y+SD + + I    K  G +V +I++   +P +L+I+ +   +  IK          C G    C G CL N       +C  +    +      Q + L+     + GF
Sbjct: 1140 CGKMNQFMCADGKCLRSFQLCDGFPDCLTGEDETECPPSMCDSTTHLSCLNGQKCISKQLECDGVDDCGDNSDEKHCTEIRLDEAALRC-QSPMYQC-DGPNFKCISDKHLCDGTNDCEEGDDEGLWCTFNCTDADDLGCSHTCRPTPVGPICSCPDDHYLDKNGVTCSKKDPCRFGQ--CSQYCSPHGSSHFCYCEDSFKLGADRSSCISDDPRKPFLIYSNRHEIRMIQSKYPGSLPMITNLVNAIALDFKYHQNGSVSIYWTDLSADK----IYTGLVDQRTILYQRTIVSYGV---------------------FNAEGIAVDWISGNIYWIDSFLDTIQVVSEDGTKRATVINQNMGNARSLAIDVEEGFMFWTDW--EESNPRIERASLAGNNRAIIWKISNIAQAGWPNGIALDTIAKRVYWADAKSDSIHTITYDGRDHVIVFRDPERLG----HCFGIDVYEGHVYFSDWRTNTISKVDKWFGSNVSIIERVATQPFSLKIVHRSKQKMQIK--------NSCDGF--KCNGICLNNGKNKATCQCTNLQSTTDDGCVDIQQVLLVATKNGVRGF 1678

HSP 3 Score: 75.485 bits (184), Expect = 1.391e-13
Identity = 124/576 (21.53%), Postives = 218/576 (37.85%), Query Frame = 1

Query:  124 HYCGKNSFFQC----ISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREK-------LCDGVNDCIENEDEWNCTNINSCNE--KTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGC-QDNGKSYNCFCYDGY--TEHDQ-KCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYND----------SSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDG-----------SFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKRVKPINLRIISKESN--RQLIKKINEHK---IGKYCSGVINTCRGSCLPNHDMPE--MPKCFGIP 1716
            H  G+++FFQC    I +  VCD   DC D  DE    P +C   + +C     C  +++       LCDG+ DC +  DE    N   C +  K  Y C N +   CI +   C+   +C    D             E+TC                           C H         VC Q C      +  C C  GY  T++D+ +C P ++  E+ +   +   + S+    ++       + R    +F++ +NL    + F    V +  ++    + N    VD+     S+        +  +A     D   N ++FT+ ++          ++IYV          ++        ++ +DP+   +FW         P+I  AN+DG                L+E+ I +P  + +D   +RLYW D     I+ +  +   +  ++ F +       P ++ + G  IY    ++  I+  HK TGK  K + K ++ ++ RI  + ++  +  +  I   K      YC    NT    C+P+ D     +PKC   P
Sbjct: 3793 HNNGESNFFQCSMQTIKEWQVCDGRWDCADGLDE---SPEMCASRKARCFRIGYCDDKKQCLDVSTALCDGIRDCFDGSDE----NPIHCKDMCKGKYRCTNGR---CIDVSARCDGRDDCGDGSD-------------EDTC------------------------GAECHHFG-------VCAQKCWMAFNHTARCHCAPGYARTKNDENECEPLSKSAEMFITNGNRLHLMSLENSQVS-------VLR---PVFNIKMNLIPGGIDFGYD-VFRTTLMYTVGIGN--SRVDIRSKKWSDGLIGSWGEEESTAGLITYDFMHNNVYFTESSEQNRGVLFDRQANIYVAKAKDTSTRTLIVNSTGTINSLAVDPIKRLIFWT---TSAPVPRILSANLDGKPIAQPFKTGSQPHKALVERNIFEPTSMVLDFSNERLYWIDVLKRTIETVSFDGRDRRTVRKFELGDT----PVTMDVLGGYIYLI-TRQGSIHRMHKFTGKTNKYVQK-IREVSPRIQIRVAHPAKHTVSHITHQKNPCQSDYCPS--NT---VCVPDQDKNGILIPKCLCGP 4287

HSP 4 Score: 74.3294 bits (181), Expect = 2.458e-13
Identity = 63/202 (31.19%), Postives = 90/202 (44.55%), Query Frame = 1

Query:  154 CISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNC-TNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFC----------KTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINK-CFKNPEVCHQG-CQDNGK--SYNCFCYDGYTEHDQKC 714
            C+ K W CD   DC D SDE NC    C   +F C  S  CIP E+ CDG  DC + EDE  C T  +S      + C N +   CI +   C+   +C  N  SL + + D            + ++ TC   C  + ++  CD   D     D +NC  +++ C  N  +C  G C D+G+    +  C DG  E  + C
Sbjct: 2829 CMPKHWQCDGQPDCADGSDEKNCDAKKCTSFEFSCESSKKCIPLEQKCDGRRDCPDGEDEHQCETECDSKGGNATFRCTNHR---CIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRCADETCVVAC--ELTAVLCDGIQDCSDGFDEKNCASLDRQCKPNEWMCDSGQCIDSGRLCDASVDCVDGSDEWVEIC 3025

HSP 5 Score: 72.0182 bits (175), Expect = 1.312e-12
Identity = 66/201 (32.84%), Postives = 84/201 (41.79%), Query Frame = 1

Query:   94 ACHFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVN-----CPPMICDKNQFKCP-----DSDLCIPREKLCDGVNDCIENEDEWN--CTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSL----ENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRN-CKHINKCFKNPEVCHQG 645
            +C  +C  +D  C K   ++CIS  W CD   DC D  DE       CPP  C   QF C       +  C+   KLCDGV DC   +DE    C N   C E   + CG+ KK  CI +  +C+   +C    D L     +CK DF      T    CI K   F CD   D    +D  + C  I +C      C  G
Sbjct: 3477 SCVSECKPNDFVCTKT--YKCISSWWRCDGQDDCGDGEDEGYFVEGVCPPFPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFE-CTE-AQFKCGDKKK--CIPLTSVCDKEKDCDDGSDELNCEITSCKPDFFACFNGTAISKCIPK--EFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSG 3669

HSP 6 Score: 67.781 bits (164), Expect = 3.122e-11
Identity = 57/192 (29.69%), Postives = 89/192 (46.35%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDC--IENED-EWNCTNINSCNEKTH-----YNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKN----PEVCHQGCQDN-GKSYNCFCYD 687
            +C  + W CD   DC D+SDE +     C +N+F C  +  C+PR  LCD   DC  + N D + +      CN+  H     Y C  +K  +C+ +   C+   +CS   D    C  +  KT++ +C +          C CP +  L+E  + C+ +N C +     P VC Q C DN   ++ C C+D
Sbjct:   53 KCYPEQWYCDGFPDCQDSSDEPSTCKRTCLENEFVC-KTGKCLPRGYLCDSQYDCGRLPNGDRDLSDEAPELCNQPLHCDYNEYAC--SKSAQCVPLFKFCDGKRDCSDGSDEHSMCHVEDPKTAD-SCEYGAAMTIDGIKCYCPKNKFLNEQGK-CEFVNHCERTKNGLPPVCSQDCTDNKNGTFTCSCFD 239

HSP 7 Score: 63.1586 bits (152), Expect = 6.522e-10
Identity = 65/218 (29.82%), Postives = 87/218 (39.91%), Query Frame = 1

Query:  103 FKCLQDDHYCGK---NSFFQCISKLWVCDYNQDCDDNSDE--VNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENC-KADFCKTSENTC-SHICINKYSSFTCDCPPDMELSEDNRNCKHI------NKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCV 717
            F C+     CG+   N+  QC+    +CD  +DC    DE    C    C + QFKC D   CIP   +CD   DC +  DE NC  I SC          T   +CI  E  C+   +C   +D  ++C     C   +  C S  CI K     CD   D     D + CK        N C    ++C      +GK     C DG  E ++ CV
Sbjct: 3525 FPCIAGQFVCGRTAQNATAQCLYASKLCDGVKDCSGGDDEEPAFCENFECTEAQFKCGDKKKCIPLTSVCDKEKDCDDGSDELNC-EITSCKPDFFACFNGTAISKCIPKEFYCDGEDDCPEGQDEPDSCFGIGECTHEQFQCTSGKCIPKRRQ--CDGTLDCRDGSDEKGCKKECAIVCDNSCVHADDLC------DGKKK---CNDGSDEDEEACV 3730

HSP 8 Score: 62.7734 bits (151), Expect = 9.314e-10
Identity = 52/169 (30.77%), Postives = 79/169 (46.75%), Query Frame = 1

Query:  106 KCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCP-PMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKD-SLENCKADFCKTSENTCSHICINK--YSSFT-CDCPPDMELSEDNRNC 597
            KC      C K    +CI K   C+  Q+CD+ +DE +CP   +CD ++F+C  + LCI + ++CDG   C++  DE +C     C +   + C N K   C+ +   C+   +C  + D S E CK +   T       +C +     SF  CD  PD    ED   C
Sbjct: 1012 KCSVSQFQCSKT---KCIIKSKRCNGVQECDNGADEEDCPRSKLCDPDEFRC-GTGLCIKQSQVCDGKMQCLDGLDEEHCNEEEKCLQGRQFRCANGKST-CLDLIFRCDGVADCEDSSDESDEFCKGNSSSTCGKMNQFMCADGKCLRSFQLCDGFPDCLTGEDETEC 1175

HSP 9 Score: 60.077 bits (144), Expect = 5.723e-9
Identity = 70/317 (22.08%), Postives = 133/317 (41.96%), Query Frame = 1

Query:  661 KSYNCFCYDGYTEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIE--MNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIV-DKDCYFPFNIVIDPVMGRLFWIDLGNENNGPK-----IKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKRVKPINLRIISKESN 1587
            ++ +CFC DGY +++ KC  + +  +  L   +      + I   + +Y+ + I  G  D+    +N+ R   + +     K   L +  L+   L V    S+      +   MN + +     A D   + L+ TD     I V  L++    K+V   +   P  I I      LFW     +NN  +     I+ + +DGS + TL+ K       L +D++   LYW D + + I+ I  N   +   +     A +  HP+ +  F N I++++ K+  +   +     DV+ + +    +   ++ K SN
Sbjct:  566 QTSSCFCRDGYIQNNTKCSASKDLKDEELFVLAQLRPSRIKILGFDKNYRTEII--GVSDL----LNVKRPSAMTFDP---KGEQLLMYDLRRHSLVVQKIGSTNYTVHGLTGIMNCEGM-----AYDFTSDNLYMTDQRRKIITVQRLSNLSIQKVVVSGNMSNPRAIAIHIAKSYLFWGSWNEDNNDDEKIPAMIERSKLDGSERKTLVSKNAMWINGLTLDLKNDYLYWCDAYRNVIERIRWNGADR---EVVVHGADKISHPYGLAFFDNHIFYTEFKKGAVKRVNVDFPDDVQEVFQYSATVFELLVFKNSN 865

HSP 10 Score: 60.077 bits (144), Expect = 7.319e-9
Identity = 54/183 (29.51%), Postives = 75/183 (40.98%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNC------------PPMICD-KNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHICINKYS---SFTCDCPPD-----MELSEDNRNCKHINKCFKNPEVC 636
            QCI   W CD   DC D SDE +C             P  CD K QF C  +  C+P+   CDG  DC +  DE NC +   C     ++C ++KK  CI +E  C+   +C   +D    C+ + C +     +  C N      ++ CD   D       L  D  +C      F  P  C
Sbjct: 2775 QCIHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRTCMPKHWQCDGQPDCADGSDEKNC-DAKKCT-SFEFSCESSKK--CIPLEQKCDGRRDCPDGEDE-HQCETE-CDSKGGNATFRCTNHRCIPMAWRCDGTDDCMDNAKSLGSDEVDCAAGRTSFHVPSRC 2951

HSP 11 Score: 56.6102 bits (135), Expect = 7.666e-8
Identity = 56/232 (24.14%), Postives = 103/232 (44.40%), Query Frame = 1

Query: 1024 STALDPARNLLFFTDYNDSSIYVMNLT--------SFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDIN-SLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKRVK-PINLRII--SKESNRQLIKKINEHKIGKYCSGVINTCRGSCLPNHD 1683
            S A D     L+F   N +SI+ +N+         +  KI +       P +I I P    LF+ +  N   G  I+     G  +  ++++++   + L ID++ ++LY++D     I   D + S  +L +    + +I   HPF + I+ + I ++D     +   +KITG D + I++    P+ L ++   +E         NE K   YC  + N  + SC  N +
Sbjct: 2395 SMAYDEVHTELYFVRANPASIWRINVADNNLESYPTEPKIVLTLTVRDRPRHIAIHPCRMLLFFTN--NAITGSVIERVYFSGFKRDQIVQEDLHDLRGLTIDLDSEKLYFSDSKDFKISRCDFDGSHRELVVSNTDIPSI---HPFELSIYDDEIIFTDWVRRSVVGVNKITGSDNRNINRATDVPVGLVVVDTKREYCTSDACADNELKCEDYCRLMANG-QASCACNGE 2620

HSP 12 Score: 55.4546 bits (132), Expect = 1.536e-7
Identity = 55/181 (30.39%), Postives = 76/181 (41.99%), Query Frame = 1

Query:  130 CGKNSF----FQCISKLWVCDYNQDCDDNSDEVNCPPMICDK-NQFK------CPDSDLCIPREKLCDGVNDCIENEDEWNC-----------TNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTC--SHICINKYSSFTCDCPPDMELSEDNRNCK 600
            C +N F      CI     C++ QDC+D SDE+ CP   C   N+F       C  +  CI     CDG NDC +  DE +C           +   SC+ KT + C  T+   C+     C+   +C+   D  +NC A  C + E +C  S  CI       CD   D    ED   C+
Sbjct: 2717 CNENEFRCQSGACIPSKARCNHMQDCNDASDEIGCPFRNCSALNEFGMTGLINCATTSQCIHPSWKCDGTNDCYDGSDEKDCFVEFDATGGSVSAPRSCDAKTQFACLATRT--CMPKHWQCDGQPDCADGSDE-KNCDAKKCTSFEFSCESSKKCIPLEQK--CDGRRDCPDGEDEHQCE 2892

HSP 13 Score: 51.9878 bits (123), Expect = 1.919e-6
Identity = 50/175 (28.57%), Postives = 74/175 (42.29%), Query Frame = 1

Query:   94 ACHFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCD----------DNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNC--GNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENT-------CSHICI-NKYSSFTCDC 558
             C   CL+++  C      +C+ + ++CD   DC           D + E+   P+ CD N++ C  S  C+P  K CDG  DC +  DE +  ++   + KT  +C  G    ++ IK          C  NK   E  K +F    E T       CS  C  NK  +FTC C
Sbjct:   76 TCKRTCLENEFVCKTG---KCLPRGYLCDSQYDCGRLPNGDRDLSDEAPELCNQPLHCDYNEYACSKSAQCVPLFKFCDGKRDCSDGSDEHSMCHVE--DPKTADSCEYGAAMTIDGIKCY--------CPKNKFLNEQGKCEFVNHCERTKNGLPPVCSQDCTDNKNGTFTCSC 237

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Celegans
Match: T13C2.6 (pep chromosome:WBcel235:II:6783427:6788255:1 gene:WBGene00020481.1 transcript:T13C2.6b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:T13C2.6)

HSP 1 Score: 139.813 bits (351), Expect = 6.129e-34
Identity = 132/525 (25.14%), Postives = 228/525 (43.43%), Query Frame = 1

Query:  154 CISKLWVCDYNQDCDDNSDEVNCPPMI--CDKNQFKCPDS----------DLCIPREKLCDGVNDCIENEDEWNC--TNINSCNEKTHYNCGNTKKLECIKIEDIC-NTNINCSTNKDSLENCKA--DFCKTSENTCSHICINKY--SSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAK---------EIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNL-SAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKE-IKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKRVK-PINLRIISKESNRQLIKKINEHKIGKYC 1635
            CI+K +VCD   DC D SDE +C  +   C   +  CP S           +CIP    C+G  DC +  DE  C  T   +C + T Y C +T  L+CI++  +C +   +C     S+ + K   + CK S   C  +C   +   +  C C    +L  +N  C  IN+C +   VC Q C +   SY C C+ GY    Q     T+     +     +      +   N H   +          +        ++D ++    +++   L  +     +  + N  L  D+       K  I +    + +    A+D   +LLF+TD     I V+++ +  +  +   D   P  I +DP +G +FW D G +    +I+ + MDG  +  ++E + +  P  LA+D  ++R+YW D   + IK I        NIKT         HPFS+ +F +R++++D +   + + +K TG D++ +  +VK P+ +RI  K++   +  K    +    C
Sbjct:  270 CINKAFVCDGELDCSDGSDEDDCADVRTECKSGERTCPASYGAYGAESGHVVCIPASSWCNGEEDCPDGGDEKECNMTAPVTCQKGTEYECPSTP-LQCIEMSKLCASAQFDCGDGNMSVCSQKKIIEMCKPSSEGC--VCRPSFVRGNNVCHCKDGYKL--ENGQCIDINEC-EIAGVCDQICLNIPGSYRCACHAGY----QISFGDTKIGSGRIANKCRAMGGDPLVLLTNRHTIRQFDLVNKMHFPVSSSPGSAVAMDFHILNGTLIWSDVLSKQILKCSIGNVSNAFLGTDM----CDKKHEIVLTGDKIHTPDGLAVDWVHDLLFWTDGGLDQINVLDMKNGKQRVLYSSDLEEPRAIAVDPEVGLIFWTDWGKK---ARIERSGMDGQHRTVIVEGDRVVWPNGLALDYVDKRVYWAD---AKIKSIFSCDYWGKNIKTVLHSHQYLRHPFSMAVFEDRLFYTDWEHDGVITVNKFTGADIRTVMDQVKSPMTVRIYHKQAQPLMQNKCENSECDHLC 774

HSP 2 Score: 77.411 bits (189), Expect = 2.397e-14
Identity = 64/194 (32.99%), Postives = 87/194 (44.85%), Query Frame = 1

Query:  109 CLQDDHYCG-----KNSF--FQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKC----PDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTC---------SHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPE 630
            C  ++H CG     ++S   F+CI   WVCD   DC+D SDE  C  + C + QF+C     D  LCIP   +CDG  DC   +DE NCT+  S     ++ C N     CI    +C+   +CS   D L    ++ C  + N C         S  CI   S + CD   D +   D +NC  I    K  E
Sbjct:   73 CGAEEHKCGEVKSARSSLERFKCIPNKWVCDGEFDCEDKSDEFQCKNVSCQEKQFQCEELSGDYSLCIPETWVCDGQRDCTNGKDEQNCTSKTSKCPDNNFQCSNGN---CIFKNWVCDGEEDCSDGSDELLTAPSN-CNRTVNQCPPGEMWKCGSGECIP--SRWRCDAEVDCKDHSDEKNCTAIQHTCKLAE 260

HSP 3 Score: 55.0694 bits (131), Expect = 1.915e-7
Identity = 44/131 (33.59%), Postives = 63/131 (48.09%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCP-PMICDKNQFKCPD-----SDL----CIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKK--LECIKIEDICNTNINCSTNKDSLENCKADFCKTSEN 507
            +CI   W CD + DC +  DE NCP   +C   + KC +     S L    CIP + +CDG  DC +  DE+ C N+ SC EK  + C         CI    +C+   +C+  KD  +NC +   K  +N
Sbjct:   44 RCIPMSWRCDGDIDCQNEEDEKNCPISEVCGAEEHKCGEVKSARSSLERFKCIPNKWVCDGEFDCEDKSDEFQCKNV-SCQEK-QFQCEELSGDYSLCIPETWVCDGQRDCTNGKDE-QNCTSKTSKCPDN 171

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Celegans
Match: T13C2.6 (pep chromosome:WBcel235:II:6783427:6788255:1 gene:WBGene00020481.1 transcript:T13C2.6a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:T13C2.6)

HSP 1 Score: 139.813 bits (351), Expect = 6.164e-34
Identity = 130/508 (25.59%), Postives = 224/508 (44.09%), Query Frame = 1

Query:  154 CISKLWVCDYNQDCDDNSDEVNCPPMI--CDKNQFKCPDS----------DLCIPREKLCDGVNDCIENEDEWNC--TNINSCNEKTHYNCGNTKKLECIKIEDIC-NTNINCSTNKDSLENCKA--DFCKTSENTCSHICINKY--SSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAK---------EIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNL-SAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKE-IKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKRVK-PINLRIISKES 1584
            CI+K +VCD   DC D SDE +C  +   C   +  CP S           +CIP    C+G  DC +  DE  C  T   +C + T Y C +T  L+CI++  +C +   +C     S+ + K   + CK S   C  +C   +   +  C C    +L  +N  C  IN+C +   VC Q C +   SY C C+ GY    Q     T+     +     +      +   N H   +          +        ++D ++    +++   L  +     +  + N  L  D+       K  I +    + +    A+D   +LLF+TD     I V+++ +  +  +   D   P  I +DP +G +FW D G +    +I+ + MDG  +  ++E + +  P  LA+D  ++R+YW D   + IK I        NIKT         HPFS+ +F +R++++D +   + + +K TG D++ +  +VK P+ +RI  K++
Sbjct:  268 CINKAFVCDGELDCSDGSDEDDCADVRTECKSGERTCPASYGAYGAESGHVVCIPASSWCNGEEDCPDGGDEKECNMTAPVTCQKGTEYECPSTP-LQCIEMSKLCASAQFDCGDGNMSVCSQKKIIEMCKPSSEGC--VCRPSFVRGNNVCHCKDGYKL--ENGQCIDINEC-EIAGVCDQICLNIPGSYRCACHAGY----QISFGDTKIGSGRIANKCRAMGGDPLVLLTNRHTIRQFDLVNKMHFPVSSSPGSAVAMDFHILNGTLIWSDVLSKQILKCSIGNVSNAFLGTDM----CDKKHEIVLTGDKIHTPDGLAVDWVHDLLFWTDGGLDQINVLDMKNGKQRVLYSSDLEEPRAIAVDPEVGLIFWTDWGKK---ARIERSGMDGQHRTVIVEGDRVVWPNGLALDYVDKRVYWAD---AKIKSIFSCDYWGKNIKTVLHSHQYLRHPFSMAVFEDRLFYTDWEHDGVITVNKFTGADIRTVMDQVKSPMTVRIYHKQA 755

HSP 2 Score: 77.411 bits (189), Expect = 2.521e-14
Identity = 65/198 (32.83%), Postives = 88/198 (44.44%), Query Frame = 1

Query:   97 CHFKCLQDDHYCG-----KNSF--FQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKC----PDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTC---------SHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPE 630
            C   C  ++H CG     ++S   F+CI   WVCD   DC+D SDE  C  + C + QF+C     D  LCIP   +CDG  DC   +DE NCT+  S     ++ C N     CI    +C+   +CS   D L    ++ C  + N C         S  CI   S + CD   D +   D +NC  I    K  E
Sbjct:   67 CPKVCGAEEHKCGEVKSARSSLERFKCIPNKWVCDGEFDCEDKSDEFQCKNVSCQEKQFQCEELSGDYSLCIPETWVCDGQRDCTNGKDEQNCTSKTSKCPDNNFQCSNGN---CIFKNWVCDGEEDCSDGSDELLTAPSN-CNRTVNQCPPGEMWKCGSGECIP--SRWRCDAEVDCKDHSDEKNCTAIQHTCKLAE 258

HSP 3 Score: 55.4546 bits (132), Expect = 1.431e-7
Identity = 44/130 (33.85%), Postives = 63/130 (48.46%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPD-----SDL----CIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKK--LECIKIEDICNTNINCSTNKDSLENCKADFCKTSEN 507
            +CI   W CD + DC +  DE NC P +C   + KC +     S L    CIP + +CDG  DC +  DE+ C N+ SC EK  + C         CI    +C+   +C+  KD  +NC +   K  +N
Sbjct:   44 RCIPMSWRCDGDIDCQNEEDEKNC-PKVCGAEEHKCGEVKSARSSLERFKCIPNKWVCDGEFDCEDKSDEFQCKNV-SCQEK-QFQCEELSGDYSLCIPETWVCDGQRDCTNGKDE-QNCTSKTSKCPDN 169

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Celegans
Match: rme-2 (Receptor Mediated Endocytosis [Source:UniProtKB/TrEMBL;Acc:O44191])

HSP 1 Score: 110.538 bits (275), Expect = 1.108e-24
Identity = 122/493 (24.75%), Postives = 195/493 (39.55%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNC----------------------PPMI------CDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCT---------------NINSCNEKTHYNCGNTKKLE---CIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYT-EHDQKC----VPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSD 1476
            QCI    VCD + DC    DEVNC                      P         C      C   D+CIP   LCDG  DC +  DE NC                +++SC+    Y+CG TK  E   CI +   CN    C    D  ++C     + +   C H C+N      C C    +L++D   C+  ++C  +  +C   C+D   S+ C C +GY  E D         TT E  + +          ++ F    +Y   + F G   I S+D     N+M    S  H D   ++S   N  + V     ++    N+ ++    + F T   P+ +          SI  M+     ++    +       +V+ P+ G + WID   + +  +I MANMDGS    LL+ +++ P  LAID     +Y+ D     I+ ++I++  +  + +  V      HP+ +  F   +YW+D
Sbjct:   69 QCIQPDLVCDGHTDCSGGDDEVNCTRRGHENMQSSTDFHDDVHLVDPTFFANEDNKCRSGYTMCHSGDVCIPDSFLCDGDLDCDDASDEKNCQTNAPSEEEYLSGQADHMHSCSAAGMYSCG-TKGSEIGVCIPMNATCNGIKECPLGDDESKHCS----ECARKRCDHTCMNTPHGARCICQEGYKLADDGLTCEDEDECATHGHLCQHFCEDRLGSFACKCANGYELETDGHSCKYETTTTPEGYLFISLGGEVRQMPLADFTDGSNYSPIQKFAGHGTIRSIDFMHRNNKMFMSISDEHGDPTGELSVSDNGLMRV--LRENVIGVSNVAVDWIGGNVFFTQKSPSPSAGI-------SICTMSGMFCRRVIEGKEQGQSYRGLVVHPMRGLIIWIDSYQKYH--RIMMANMDGSQVRILLDNKLEVPSALAIDYIRHDVYFGDVERQLIERVNIDTKERRVVISNGV-----HHPYDMAYFNGFLYWAD 540

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Fly
Match: LpR1 (gene:FBgn0066101 transcript:FBtr0301466)

HSP 1 Score: 191.815 bits (486), Expect = 5.317e-51
Identity = 165/705 (23.40%), Postives = 294/705 (41.70%), Query Frame = 1

Query:   79 CLNFYACHFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDE--VNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCT-------NINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLEN-CKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYT---EHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSI--SNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYF-HPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKRVKPINLRIISKESNRQLIKKINEHKIGKYCSGVINTCRGSCLPNHDMPEMPKCFGIPRIEEKIRSKNQSLWLILIPVVILGFVCIVLFKY-----RFSRTRITK-QPESNRVFVYDSVQFYED--QNSLHDD-----------NTIISDTVPIINNSE*VFPVTVLLLQRFSTLVNFV-----SMFHYWKLVFLSIQYKF 2073
            C N       CL  ++ C       C+   W+CD ++DC D  DE   NC  + C  +QF+C D   CIP    C+G  DC +  DE +C        N   CN  + ++CG     +C+ +  +C+   +C   +D     C  + C +    C H CI+      C+C    +LS D RNC+ IN+C + P  C Q C +    + C C  GY    ++  +C  +     + L         ++    +     + +     D +F       R  M+F+S +  +                 +Y + I   N++ + +   ++++   A+D   N ++FTD +  +I + N        +V      P +I +DP+ G ++W D G     P+I+ A MDGS + T++  ++K P  + +D+ ++R+YW D   + I   + +   +  +    + + EY  HPFSI  F + +YW+D  +  ++ A+K TG+DV+ +        + ++       +     +     +C  V   C   CLP             PRI E+   +        + +++ G +C+    Y     R  R R TK +P+S R  +   VQ      +  ++DD            T ++D  P+ N+++ +   T    Q  S  +  V     S F     V L I Y++
Sbjct:  186 CANVTKTTTPCLSHEYQC--KDRITCLHHSWLCDGDRDCPDGDDEHTANCKNVTCRADQFQCGDRS-CIPGHLTCNGDKDCADGSDERDCGLSLSLGINQGGCNATSEFDCGGG---QCVPLSKVCDKRKDCPDGEDEPAGKCGINECASKNGGCMHQCIDLKVGHHCECHEGYKLSPDKRNCQDINEC-EVPGKCSQICVNEIGGFKCECEAGYMRDPKNHTRCKASEGHASLLLARRHDIRKIALDHMEMTSIVNSTKAATALDFVF-------RTGMIFWSDVTTQ----------------SIYKAPIDEGNEKTVVLTKSSVTSDGLAVDWIYNHVYFTDTHKCTIELTNFEGSMGKVLVKDSLDIPRSIALDPIEGWMYWSDWGAS---PRIERAGMDGSHRTTIISYDVKWPNGITLDLVKKRIYWVDGKLNVISSANYDGSQRSQV----LYSGEYLRHPFSITTFEDNVYWTDWDKQAVFKANKFTGEDVEPV------TAMHMLQHPMVVHVYHPYRQPDGVNHCQSVNGHCSHLCLP------------APRINER-SPRISCACPTGLKLMVDGLMCVEDPLYLPPVTRPPRARKTKPRPKSPRRRLPTGVQVGHADIRIEINDDLQLSTRLPLLPTTFVADQRPVKNHTQ-IEKTTTPSEQPDSGFIALVVIASLSGFAVLLSVLLLIGYRY 833

HSP 2 Score: 60.4622 bits (145), Expect = 4.410e-9
Identity = 67/216 (31.02%), Postives = 95/216 (43.98%), Query Frame = 1

Query:  109 CLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVN--CPPMICDKNQFKCPDSD-LCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKT-SENTCSH-ICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQ-GCQDN----GKSYNC----FCYDGYTEHDQKC 714
            C  D   CG  +   CI   W CD   DC D SDE N  C    C  +++ C   +  C+P   +CD   DC +  DE NC      +E   + CGN +   CI+    C+ + +C    D  E C    C + +E+TC++  CI K   + CD  PD     D R+C ++ K    P + H+  C+D       S+ C     C DG  EH   C
Sbjct:   31 CSSDQFRCGNGN---CIPNKWRCDQESDCADGSDEANELCRARTCSPDEYACKSGEGQCVPLAWMCDQSKDCSDGSDEHNCNQTCRADE---FTCGNGR---CIQKRWKCDHDDDCGDGSDEKE-CPVVPCDSVAEHTCTNGACIAK--RWVCDGDPDCSDGSDERSCANVTK-TTTPCLSHEYQCKDRITCLHHSWLCDGDRDCPDGDDEHTANC 233

HSP 3 Score: 55.8398 bits (133), Expect = 1.326e-7
Identity = 50/211 (23.70%), Postives = 77/211 (36.49%), Query Frame = 1

Query:   97 CHFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDS---------------------------------------DLCIPREKLCDGVNDCIENEDEWNCTNINSCNE---KTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCS-HICINKYSSFTCDCPPDMELSEDNRNC 597
            C  +    D Y  K+   QC+   W+CD ++DC D SDE NC    C  ++F C +                                          CI +  +CDG  DC +  DE +C N+           Y C +  ++ C+    +C+ + +C    D    NCK   C+  +  C    CI  +   TC+   D     D R+C
Sbjct:   67 CRARTCSPDEYACKSGEGQCVPLAWMCDQSKDCSDGSDEHNC-NQTCRADEFTCGNGRCIQKRWKCDHDDDCGDGSDEKECPVVPCDSVAEHTCTNGACIAKRWVCDGDPDCSDGSDERSCANVTKTTTPCLSHEYQCKD--RITCLHHSWLCDGDRDCPDGDDEHTANCKNVTCRADQFQCGDRSCIPGH--LTCNGDKDCADGSDERDC 272

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Fly
Match: LpR1 (gene:FBgn0066101 transcript:FBtr0335238)

HSP 1 Score: 191.815 bits (486), Expect = 6.166e-51
Identity = 165/705 (23.40%), Postives = 295/705 (41.84%), Query Frame = 1

Query:   79 CLNFYACHFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDE--VNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCT-------NINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLEN-CKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYT---EHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSI--SNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYF-HPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKRVKPINLRIISKESNRQLIKKINEHKIGKYCSGVINTCRGSCLPNHDMPEMPKCFGIPRIEEKIRSKNQSLWLILIPVVILGFVCIVLFKY-----RFSRTRITK-QPESNRVFVYDSVQF--YEDQNSLHDD-----------NTIISDTVPIINNSE*VFPVTVLLLQRFSTLVNFV-----SMFHYWKLVFLSIQYKF 2073
            C N       CL  ++ C       C+   W+CD ++DC D  DE   NC  + C  +QF+C D   CIP    C+G  DC +  DE +C        N   CN  + ++CG     +C+ +  +C+   +C   +D     C  + C +    C H CI+      C+C    +LS D RNC+ IN+C + P  C Q C +    + C C  GY    ++  +C  +     + L         ++    +     + +     D +F       R  M+F+S +  +                 +Y + I   N++ + +   ++++   A+D   N ++FTD +  +I + N        +V      P +I +DP+ G ++W D G     P+I+ A MDGS + T++  ++K P  + +D+ ++R+YW D   + I   + +   +  +    + + EY  HPFSI  F + +YW+D  +  ++ A+K TG+DV+ +        + ++       +     +     +C  V   C   CLP             PRI E+   +        + +++ G +C+    Y     R  R R TK +P+S R  +   VQ    + +  ++DD            T ++D  P+ N+++ +   T    Q  S  +  V     S F     V L I Y++
Sbjct:  184 CANVTKTTTPCLSHEYQC--KDRITCLHHSWLCDGDRDCPDGDDEHTANCKNVTCRADQFQCGDRS-CIPGHLTCNGDKDCADGSDERDCGLSLSLGINQGGCNATSEFDCGGG---QCVPLSKVCDKRKDCPDGEDEPAGKCGINECASKNGGCMHQCIDLKVGHHCECHEGYKLSPDKRNCQDINEC-EVPGKCSQICVNEIGGFKCECEAGYMRDPKNHTRCKASEGHASLLLARRHDIRKIALDHMEMTSIVNSTKAATALDFVF-------RTGMIFWSDVTTQ----------------SIYKAPIDEGNEKTVVLTKSSVTSDGLAVDWIYNHVYFTDTHKCTIELTNFEGSMGKVLVKDSLDIPRSIALDPIEGWMYWSDWGAS---PRIERAGMDGSHRTTIISYDVKWPNGITLDLVKKRIYWVDGKLNVISSANYDGSQRSQV----LYSGEYLRHPFSITTFEDNVYWTDWDKQAVFKANKFTGEDVEPV------TAMHMLQHPMVVHVYHPYRQPDGVNHCQSVNGHCSHLCLP------------APRINER-SPRISCACPTGLKLMVDGLMCVEDPLYLPPVTRPPRARKTKPRPKSPRRRLPTGVQVGHADIRIEINDDLQLSTRLPLLPTTFVADQRPVKNHTQ-IEKTTTPSEQPDSGFIALVVIASLSGFAVLLSVLLLIGYRY 831

HSP 2 Score: 73.9442 bits (180), Expect = 3.348e-13
Identity = 75/214 (35.05%), Postives = 99/214 (46.26%), Query Frame = 1

Query:  109 CLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPM-ICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKT-SENTCSH-ICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQ-GCQDN----GKSYNC----FCYDGYTEHDQKC 714
            C  D   CG  +   CI   W CD   DC D SDE N   M  C  N+FKC   D CIPR  LCDG NDC +  DE +C      +E   + CGN +   CI+    C+ + +C    D  E C    C + +E+TC++  CI K   + CD  PD     D R+C ++ K    P + H+  C+D       S+ C     C DG  EH   C
Sbjct:   31 CSSDQFRCGNGN---CIPNKWRCDQESDCADGSDEANELCMNACPNNEFKCQTVDQCIPRSWLCDGSNDCRDKSDEAHCNQTCRADE---FTCGNGR---CIQKRWKCDHDDDCGDGSDEKE-CPVVPCDSVAEHTCTNGACIAK--RWVCDGDPDCSDGSDERSCANVTK-TTTPCLSHEYQCKDRITCLHHSWLCDGDRDCPDGDDEHTANC 231

HSP 3 Score: 50.447 bits (119), Expect = 6.138e-6
Identity = 51/172 (29.65%), Postives = 76/172 (44.19%), Query Frame = 1

Query:   97 CHFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNE---KTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCS-HICINKYSSFTCDCPPDMELSEDNRNC 597
            C+  C  D+  CG     +CI K W CD++ DC D SDE  CP + CD        +  CI +  +CDG  DC +  DE +C N+           Y C +  ++ C+    +C+ + +C    D    NCK   C+  +  C    CI  +   TC+   D     D R+C
Sbjct:  106 CNQTCRADEFTCGNG---RCIQKRWKCDHDDDCGDGSDEKECPVVPCDSVAEHTCTNGACIAKRWVCDGDPDCSDGSDERSCANVTKTTTPCLSHEYQCKD--RITCLHHSWLCDGDRDCPDGDDEHTANCKNVTCRADQFQCGDRSCIPGH--LTCNGDKDCADGSDERDC 270

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Fly
Match: LpR1 (gene:FBgn0066101 transcript:FBtr0301469)

HSP 1 Score: 191.815 bits (486), Expect = 9.069e-51
Identity = 167/705 (23.69%), Postives = 295/705 (41.84%), Query Frame = 1

Query:   79 CLNFYACHFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDE--VNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCT-------NINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLEN-CKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYT---EHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSI--SNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYF-HPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKRVKPINLRIISKESNRQLIKKINEHKIGKYCSGVINTCRGSCLPNHDMPEMPKCFGIPRIEEKIRSKNQSLWLILIPVVILGFVCIVLFKY-----RFSRTRITK-QPESNRVFVYDSVQFYED--QNSLHDD-----------NTIISDTVPIINNSE*VFPVTVLLLQRFSTLVNFV-----SMFHYWKLVFLSIQYKF 2073
            C N       CL  ++ C       C+   W+CD ++DC D  DE   NC  + C  +QF+C D   CIP    C+G  DC +  DE +C        N   CN  + ++CG     +C+ +  +C+   +C   +D     C  + C +    C H CI+      C+C    +LS D RNC+ IN+C + P  C Q C +    + C C  GY    ++  +C  +     + L         ++       H +   I        +LD  + R  M+F+S +  +                 +Y + I   N++ + +   ++++   A+D   N ++FTD +  +I + N        +V      P +I +DP+ G ++W D G     P+I+ A MDGS + T++  ++K P  + +D+ ++R+YW D   + I   + +   +  +    + + EY  HPFSI  F + +YW+D  +  ++ A+K TG+DV+ +        + ++       +     +     +C  V   C   CLP             PRI E+   +        + +++ G +C+    Y     R  R R TK +P+S R  +   VQ      +  ++DD            T ++D  P+ N+++ +   T    Q  S  +  V     S F     V L I Y++
Sbjct:  293 CANVTKTTTPCLSHEYQC--KDRITCLHHSWLCDGDRDCPDGDDEHTANCKNVTCRADQFQCGDRS-CIPGHLTCNGDKDCADGSDERDCGLSLSLGINQGGCNATSEFDCGGG---QCVPLSKVCDKRKDCPDGEDEPAGKCGINECASKNGGCMHQCIDLKVGHHCECHEGYKLSPDKRNCQDINEC-EVPGKCSQICVNEIGGFKCECEAGYMRDPKNHTRCKASEGHASLLLARRHDIRKIALD------HMEMTSIVNSTKAATALDF-VFRTGMIFWSDVTTQ----------------SIYKAPIDEGNEKTVVLTKSSVTSDGLAVDWIYNHVYFTDTHKCTIELTNFEGSMGKVLVKDSLDIPRSIALDPIEGWMYWSDWGAS---PRIERAGMDGSHRTTIISYDVKWPNGITLDLVKKRIYWVDGKLNVISSANYDGSQRSQV----LYSGEYLRHPFSITTFEDNVYWTDWDKQAVFKANKFTGEDVEPV------TAMHMLQHPMVVHVYHPYRQPDGVNHCQSVNGHCSHLCLP------------APRINER-SPRISCACPTGLKLMVDGLMCVEDPLYLPPVTRPPRARKTKPRPKSPRRRLPTGVQVGHADIRIEINDDLQLSTRLPLLPTTFVADQRPVKNHTQ-IEKTTTPSEQPDSGFIALVVIASLSGFAVLLSVLLLIGYRY 940

HSP 2 Score: 50.8322 bits (120), Expect = 4.979e-6
Identity = 51/172 (29.65%), Postives = 76/172 (44.19%), Query Frame = 1

Query:   97 CHFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNE---KTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCS-HICINKYSSFTCDCPPDMELSEDNRNC 597
            C+  C  D+  CG     +CI K W CD++ DC D SDE  CP + CD        +  CI +  +CDG  DC +  DE +C N+           Y C +  ++ C+    +C+ + +C    D    NCK   C+  +  C    CI  +   TC+   D     D R+C
Sbjct:  215 CNQTCRADEFTCGNG---RCIQKRWKCDHDDDCGDGSDEKECPVVPCDSVAEHTCTNGACIAKRWVCDGDPDCSDGSDERSCANVTKTTTPCLSHEYQCKD--RITCLHHSWLCDGDRDCPDGDDEHTANCKNVTCRADQFQCGDRSCIPGH--LTCNGDKDCADGSDERDC 379

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Fly
Match: LpR1 (gene:FBgn0066101 transcript:FBtr0301467)

HSP 1 Score: 191.815 bits (486), Expect = 9.510e-51
Identity = 167/705 (23.69%), Postives = 295/705 (41.84%), Query Frame = 1

Query:   79 CLNFYACHFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDE--VNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCT-------NINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLEN-CKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYT---EHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSI--SNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYF-HPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKRVKPINLRIISKESNRQLIKKINEHKIGKYCSGVINTCRGSCLPNHDMPEMPKCFGIPRIEEKIRSKNQSLWLILIPVVILGFVCIVLFKY-----RFSRTRITK-QPESNRVFVYDSVQFYED--QNSLHDD-----------NTIISDTVPIINNSE*VFPVTVLLLQRFSTLVNFV-----SMFHYWKLVFLSIQYKF 2073
            C N       CL  ++ C       C+   W+CD ++DC D  DE   NC  + C  +QF+C D   CIP    C+G  DC +  DE +C        N   CN  + ++CG     +C+ +  +C+   +C   +D     C  + C +    C H CI+      C+C    +LS D RNC+ IN+C + P  C Q C +    + C C  GY    ++  +C  +     + L         ++       H +   I        +LD  + R  M+F+S +  +                 +Y + I   N++ + +   ++++   A+D   N ++FTD +  +I + N        +V      P +I +DP+ G ++W D G     P+I+ A MDGS + T++  ++K P  + +D+ ++R+YW D   + I   + +   +  +    + + EY  HPFSI  F + +YW+D  +  ++ A+K TG+DV+ +        + ++       +     +     +C  V   C   CLP             PRI E+   +        + +++ G +C+    Y     R  R R TK +P+S R  +   VQ      +  ++DD            T ++D  P+ N+++ +   T    Q  S  +  V     S F     V L I Y++
Sbjct:  334 CANVTKTTTPCLSHEYQC--KDRITCLHHSWLCDGDRDCPDGDDEHTANCKNVTCRADQFQCGDRS-CIPGHLTCNGDKDCADGSDERDCGLSLSLGINQGGCNATSEFDCGGG---QCVPLSKVCDKRKDCPDGEDEPAGKCGINECASKNGGCMHQCIDLKVGHHCECHEGYKLSPDKRNCQDINEC-EVPGKCSQICVNEIGGFKCECEAGYMRDPKNHTRCKASEGHASLLLARRHDIRKIALD------HMEMTSIVNSTKAATALDF-VFRTGMIFWSDVTTQ----------------SIYKAPIDEGNEKTVVLTKSSVTSDGLAVDWIYNHVYFTDTHKCTIELTNFEGSMGKVLVKDSLDIPRSIALDPIEGWMYWSDWGAS---PRIERAGMDGSHRTTIISYDVKWPNGITLDLVKKRIYWVDGKLNVISSANYDGSQRSQV----LYSGEYLRHPFSITTFEDNVYWTDWDKQAVFKANKFTGEDVEPV------TAMHMLQHPMVVHVYHPYRQPDGVNHCQSVNGHCSHLCLP------------APRINER-SPRISCACPTGLKLMVDGLMCVEDPLYLPPVTRPPRARKTKPRPKSPRRRLPTGVQVGHADIRIEINDDLQLSTRLPLLPTTFVADQRPVKNHTQ-IEKTTTPSEQPDSGFIALVVIASLSGFAVLLSVLLLIGYRY 981

HSP 2 Score: 60.4622 bits (145), Expect = 5.552e-9
Identity = 67/216 (31.02%), Postives = 95/216 (43.98%), Query Frame = 1

Query:  109 CLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVN--CPPMICDKNQFKCPDSD-LCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKT-SENTCSH-ICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQ-GCQDN----GKSYNC----FCYDGYTEHDQKC 714
            C  D   CG  +   CI   W CD   DC D SDE N  C    C  +++ C   +  C+P   +CD   DC +  DE NC      +E   + CGN +   CI+    C+ + +C    D  E C    C + +E+TC++  CI K   + CD  PD     D R+C ++ K    P + H+  C+D       S+ C     C DG  EH   C
Sbjct:  179 CSSDQFRCGNGN---CIPNKWRCDQESDCADGSDEANELCRARTCSPDEYACKSGEGQCVPLAWMCDQSKDCSDGSDEHNCNQTCRADE---FTCGNGR---CIQKRWKCDHDDDCGDGSDEKE-CPVVPCDSVAEHTCTNGACIAKR--WVCDGDPDCSDGSDERSCANVTK-TTTPCLSHEYQCKDRITCLHHSWLCDGDRDCPDGDDEHTANC 381

HSP 3 Score: 55.4546 bits (132), Expect = 1.589e-7
Identity = 50/211 (23.70%), Postives = 77/211 (36.49%), Query Frame = 1

Query:   97 CHFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDS---------------------------------------DLCIPREKLCDGVNDCIENEDEWNCTNINSCNE---KTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCS-HICINKYSSFTCDCPPDMELSEDNRNC 597
            C  +    D Y  K+   QC+   W+CD ++DC D SDE NC    C  ++F C +                                          CI +  +CDG  DC +  DE +C N+           Y C +  ++ C+    +C+ + +C    D    NCK   C+  +  C    CI  +   TC+   D     D R+C
Sbjct:  215 CRARTCSPDEYACKSGEGQCVPLAWMCDQSKDCSDGSDEHNC-NQTCRADEFTCGNGRCIQKRWKCDHDDDCGDGSDEKECPVVPCDSVAEHTCTNGACIAKRWVCDGDPDCSDGSDERSCANVTKTTTPCLSHEYQCKD--RITCLHHSWLCDGDRDCPDGDDEHTANCKNVTCRADQFQCGDRSCIPGH--LTCNGDKDCADGSDERDC 420

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Fly
Match: LpR1 (gene:FBgn0066101 transcript:FBtr0301470)

HSP 1 Score: 191.815 bits (486), Expect = 1.253e-50
Identity = 167/705 (23.69%), Postives = 296/705 (41.99%), Query Frame = 1

Query:   79 CLNFYACHFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDE--VNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCT-------NINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLEN-CKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYT---EHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSI--SNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYF-HPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKRVKPINLRIISKESNRQLIKKINEHKIGKYCSGVINTCRGSCLPNHDMPEMPKCFGIPRIEEKIRSKNQSLWLILIPVVILGFVCIVLFKY-----RFSRTRITK-QPESNRVFVYDSVQF--YEDQNSLHDD-----------NTIISDTVPIINNSE*VFPVTVLLLQRFSTLVNFV-----SMFHYWKLVFLSIQYKF 2073
            C N       CL  ++ C       C+   W+CD ++DC D  DE   NC  + C  +QF+C D   CIP    C+G  DC +  DE +C        N   CN  + ++CG     +C+ +  +C+   +C   +D     C  + C +    C H CI+      C+C    +LS D RNC+ IN+C + P  C Q C +    + C C  GY    ++  +C  +     + L         ++       H +   I        +LD  + R  M+F+S +  +                 +Y + I   N++ + +   ++++   A+D   N ++FTD +  +I + N        +V      P +I +DP+ G ++W D G     P+I+ A MDGS + T++  ++K P  + +D+ ++R+YW D   + I   + +   +  +    + + EY  HPFSI  F + +YW+D  +  ++ A+K TG+DV+ +        + ++       +     +     +C  V   C   CLP             PRI E+   +        + +++ G +C+    Y     R  R R TK +P+S R  +   VQ    + +  ++DD            T ++D  P+ N+++ +   T    Q  S  +  V     S F     V L I Y++
Sbjct:  373 CANVTKTTTPCLSHEYQC--KDRITCLHHSWLCDGDRDCPDGDDEHTANCKNVTCRADQFQCGDRS-CIPGHLTCNGDKDCADGSDERDCGLSLSLGINQGGCNATSEFDCGGG---QCVPLSKVCDKRKDCPDGEDEPAGKCGINECASKNGGCMHQCIDLKVGHHCECHEGYKLSPDKRNCQDINEC-EVPGKCSQICVNEIGGFKCECEAGYMRDPKNHTRCKASEGHASLLLARRHDIRKIALD------HMEMTSIVNSTKAATALDF-VFRTGMIFWSDVTTQ----------------SIYKAPIDEGNEKTVVLTKSSVTSDGLAVDWIYNHVYFTDTHKCTIELTNFEGSMGKVLVKDSLDIPRSIALDPIEGWMYWSDWGAS---PRIERAGMDGSHRTTIISYDVKWPNGITLDLVKKRIYWVDGKLNVISSANYDGSQRSQV----LYSGEYLRHPFSITTFEDNVYWTDWDKQAVFKANKFTGEDVEPV------TAMHMLQHPMVVHVYHPYRQPDGVNHCQSVNGHCSHLCLP------------APRINER-SPRISCACPTGLKLMVDGLMCVEDPLYLPPVTRPPRARKTKPRPKSPRRRLPTGVQVGHADIRIEINDDLQLSTRLPLLPTTFVADQRPVKNHTQ-IEKTTTPSEQPDSGFIALVVIASLSGFAVLLSVLLLIGYRY 1020

HSP 2 Score: 72.0182 bits (175), Expect = 1.496e-12
Identity = 74/251 (29.48%), Postives = 98/251 (39.04%), Query Frame = 1

Query:  109 CLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPM-ICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCS------------------------------------HICINKY---SSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQ-GCQDN----GKSYNC----FCYDGYTEHDQKC 714
            C  D   CG  +   CI   W CD   DC D SDE N   M  C  N+FKC   D CIPR  LCDG NDC +  DE +C    +C+    Y C  + + +C+ +  +C+ + +CS   D   NC    C+  E TC                                     H C N       + CD  PD     D R+C ++ K    P + H+  C+D       S+ C     C DG  EH   C
Sbjct:  179 CSSDQFRCGNGN---CIPNKWRCDQESDCADGSDEANELCMNACPNNEFKCQTVDQCIPRSWLCDGSNDCRDKSDEAHC-RARTCSPD-EYAC-KSGEGQCVPLAWMCDQSKDCSDGSDE-HNCN-QTCRADEFTCGNGRCIQKRWKCDHDDDCGDGSDEKECPVVPCDSVAEHTCTNGACIAKRWVCDGDPDCSDGSDERSCANVTK-TTTPCLSHEYQCKDRITCLHHSWLCDGDRDCPDGDDEHTANC 420

HSP 3 Score: 55.0694 bits (131), Expect = 2.396e-7
Identity = 50/211 (23.70%), Postives = 77/211 (36.49%), Query Frame = 1

Query:   97 CHFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDS---------------------------------------DLCIPREKLCDGVNDCIENEDEWNCTNINSCNE---KTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCS-HICINKYSSFTCDCPPDMELSEDNRNC 597
            C  +    D Y  K+   QC+   W+CD ++DC D SDE NC    C  ++F C +                                          CI +  +CDG  DC +  DE +C N+           Y C +  ++ C+    +C+ + +C    D    NCK   C+  +  C    CI  +   TC+   D     D R+C
Sbjct:  254 CRARTCSPDEYACKSGEGQCVPLAWMCDQSKDCSDGSDEHNC-NQTCRADEFTCGNGRCIQKRWKCDHDDDCGDGSDEKECPVVPCDSVAEHTCTNGACIAKRWVCDGDPDCSDGSDERSCANVTKTTTPCLSHEYQCKD--RITCLHHSWLCDGDRDCPDGDDEHTANCKNVTCRADQFQCGDRSCIPGH--LTCNGDKDCADGSDERDC 459

HSP 4 Score: 52.7582 bits (125), Expect = 1.274e-6
Identity = 51/172 (29.65%), Postives = 70/172 (40.70%), Query Frame = 1

Query:  154 CISKLWVCDYNQDCDDNSDE---------------------VNCPP-----------------------MICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHI-CINK 534
            CI   +VCD + DC D+SDE                      NC P                         C  N+FKC   D CIPR  LCDG NDC +  DE +C    +C+    Y C  + + +C+ +  +C+ + +CS   D   NC    C+  E TC +  CI K
Sbjct:  148 CIPIRFVCDGDADCKDHSDEQIKECKFIEATCSSDQFRCGNGNCIPNKWRCDQESDCADGSDEANELCMNACPNNEFKCQTVDQCIPRSWLCDGSNDCRDKSDEAHC-RARTCSPD-EYAC-KSGEGQCVPLAWMCDQSKDCSDGSDE-HNCN-QTCRADEFTCGNGRCIQK 314

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Zebrafish
Match: vldlr (very low density lipoprotein receptor [Source:ZFIN;Acc:ZDB-GENE-040426-803])

HSP 1 Score: 197.208 bits (500), Expect = 7.846e-53
Identity = 137/484 (28.31%), Postives = 227/484 (46.90%), Query Frame = 1

Query:  106 KCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKA-KEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLS----AFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYF-HPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            KC   +  CG     +CI + W CD + DC D SDE NC    C  +QFKC D   CI   + C+G  DC++  DE NC N+  CN    + C   +  ECI++  +CN   +C    D  ++ C  + C  +   CSHIC +    F CDC P ++L  D + C  +N+C  NP +C Q C +    Y C C++GY        PTT   +               I  L    +   +I     +  +LD +  + +M+F++ L  K                    S++ +KQ+ E + K +         A+D     ++++D    SI V N     K  + +     P +I +DP+ G L+W D G      KI+ + M+G+ +  L+E +I+ P  + +D+ + RLYW D     +  +D+N  ++  +    + + +Y  HPF++ +F +R++W+D +   IY A+K TG DV ++
Sbjct:  234 KCSPSEMQCGSG---ECIHRKWRCDGDPDCKDGSDEKNCSARNCRPDQFKCDDGS-CIHGSRQCNGFRDCVDGTDEVNCKNLTQCNSSDQFKC---RSGECIEMSKVCNKVRDCPDWSDEPIKECNMNECLINNGGCSHICRDLTIGFECDCTPGLQLI-DRKTCGDVNECL-NPGICSQICINLKGGYKCECHNGYQMD-----PTTGVCKAVGKEPCLIFTNRRDIRKLGLERREYTQIVEQLRNTVALDADFIQ-QMIFWADLGQK-----------------AIFSTVLDKQD-ESHKKVIDDVQMPVGIAVDWIYKNIYWSDLGSKSITVANFNGTKKKVLFNSGLKEPASIAVDPLSGFLYWSDWGEP---AKIEKSGMNGNDRQVLVETDIQWPNGITLDLIKGRLYWVDSKLHMLCSVDLNGDNRRKV----LQSPDYLAHPFALTVFEDRVFWTDGENEAIYGANKFTGSDVTLL 677

HSP 2 Score: 65.855 bits (159), Expect = 1.279e-10
Identity = 55/183 (30.05%), Postives = 82/183 (44.81%), Query Frame = 1

Query:   76 ICLNFY----ACHFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKT----HYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHI-CINKYSSFTCDCPPDMELSEDNRNC 597
            +C   +    A   +C Q    CG     +CI  +W CD + DC D SDE +C    C +  F C  S  CIP+   CDG  DC +  DE    +I  C+ +T     ++CG     +CI +   C+   +C   +D + NC    C   E TCS   C+++   F C+   D     D ++C
Sbjct:   14 VCFQLWGFSRASRAECEQSQFQCGNG---RCIPSVWQCDGDMDCSDGSDETSCVRKTCAEVDFVC-RSGQCIPKRWQCDGEPDCEDGSDE----SIEMCHTRTCRVNEFSCG-VGSTQCIPVFWKCDGEKDCDNGEDEI-NCGNITCAPLEFTCSSGRCVSR--KFVCNGEDDCGDGSDEQDC 184

HSP 3 Score: 62.003 bits (149), Expect = 1.950e-9
Identity = 67/212 (31.60%), Postives = 97/212 (45.75%), Query Frame = 1

Query:   97 CHFK-CLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDI-CNTNINCSTNKDSLENCKAD-----FCKTSENTC-SHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQG-CQDNGKSYNCF--CYDGYTE 699
            CH + C  ++  CG  S  QCI   W CD  +DCD+  DE+NC  + C   +F C  S  C+ R+ +C+G +DC +  DE +C   +SC+  +   CGN     CI    +  +       + +S E C  +      C  SE  C S  CI++   + CD  PD +   D +NC   N C  +   C  G C    +  N F  C DG  E
Sbjct:  104 CHTRTCRVNEFSCGVGST-QCIPVFWKCDGEKDCDNGEDEINCGNITCAPLEFTC-SSGRCVSRKFVCNGEDDCGDGSDEQDCAP-SSCS-PSEIPCGNNT---CIPRSWLCDDDVDCQDQSDESPERCGHNPTPPAKCSPSEMQCGSGECIHR--KWRCDGDPDCKDGSDEKNCSARN-CRPDQFKCDDGSCIHGSRQCNGFRDCVDGTDE 305

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Zebrafish
Match: vldlr (very low density lipoprotein receptor [Source:ZFIN;Acc:ZDB-GENE-040426-803])

HSP 1 Score: 197.208 bits (500), Expect = 9.546e-53
Identity = 137/484 (28.31%), Postives = 227/484 (46.90%), Query Frame = 1

Query:  106 KCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKA-KEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLS----AFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYF-HPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            KC   +  CG     +CI + W CD + DC D SDE NC    C  +QFKC D   CI   + C+G  DC++  DE NC N+  CN    + C   +  ECI++  +CN   +C    D  ++ C  + C  +   CSHIC +    F CDC P ++L  D + C  +N+C  NP +C Q C +    Y C C++GY        PTT   +               I  L    +   +I     +  +LD +  + +M+F++ L  K                    S++ +KQ+ E + K +         A+D     ++++D    SI V N     K  + +     P +I +DP+ G L+W D G      KI+ + M+G+ +  L+E +I+ P  + +D+ + RLYW D     +  +D+N  ++  +    + + +Y  HPF++ +F +R++W+D +   IY A+K TG DV ++
Sbjct:  234 KCSPSEMQCGSG---ECIHRKWRCDGDPDCKDGSDEKNCSARNCRPDQFKCDDGS-CIHGSRQCNGFRDCVDGTDEVNCKNLTQCNSSDQFKC---RSGECIEMSKVCNKVRDCPDWSDEPIKECNMNECLINNGGCSHICRDLTIGFECDCTPGLQLI-DRKTCGDVNECL-NPGICSQICINLKGGYKCECHNGYQMD-----PTTGVCKAVGKEPCLIFTNRRDIRKLGLERREYTQIVEQLRNTVALDADFIQ-QMIFWADLGQK-----------------AIFSTVLDKQD-ESHKKVIDDVQMPVGIAVDWIYKNIYWSDLGSKSITVANFNGTKKKVLFNSGLKEPASIAVDPLSGFLYWSDWGEP---AKIEKSGMNGNDRQVLVETDIQWPNGITLDLIKGRLYWVDSKLHMLCSVDLNGDNRRKV----LQSPDYLAHPFALTVFEDRVFWTDGENEAIYGANKFTGSDVTLL 677

HSP 2 Score: 65.855 bits (159), Expect = 1.325e-10
Identity = 55/183 (30.05%), Postives = 82/183 (44.81%), Query Frame = 1

Query:   76 ICLNFY----ACHFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKT----HYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHI-CINKYSSFTCDCPPDMELSEDNRNC 597
            +C   +    A   +C Q    CG     +CI  +W CD + DC D SDE +C    C +  F C  S  CIP+   CDG  DC +  DE    +I  C+ +T     ++CG     +CI +   C+   +C   +D + NC    C   E TCS   C+++   F C+   D     D ++C
Sbjct:   14 VCFQLWGFSRASRAECEQSQFQCGNG---RCIPSVWQCDGDMDCSDGSDETSCVRKTCAEVDFVC-RSGQCIPKRWQCDGEPDCEDGSDE----SIEMCHTRTCRVNEFSCG-VGSTQCIPVFWKCDGEKDCDNGEDEI-NCGNITCAPLEFTCSSGRCVSR--KFVCNGEDDCGDGSDEQDC 184

HSP 3 Score: 62.003 bits (149), Expect = 2.108e-9
Identity = 67/212 (31.60%), Postives = 97/212 (45.75%), Query Frame = 1

Query:   97 CHFK-CLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDI-CNTNINCSTNKDSLENCKAD-----FCKTSENTC-SHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQG-CQDNGKSYNCF--CYDGYTE 699
            CH + C  ++  CG  S  QCI   W CD  +DCD+  DE+NC  + C   +F C  S  C+ R+ +C+G +DC +  DE +C   +SC+  +   CGN     CI    +  +       + +S E C  +      C  SE  C S  CI++   + CD  PD +   D +NC   N C  +   C  G C    +  N F  C DG  E
Sbjct:  104 CHTRTCRVNEFSCGVGST-QCIPVFWKCDGEKDCDNGEDEINCGNITCAPLEFTC-SSGRCVSRKFVCNGEDDCGDGSDEQDCA-PSSCS-PSEIPCGNNT---CIPRSWLCDDDVDCQDQSDESPERCGHNPTPPAKCSPSEMQCGSGECIHR--KWRCDGDPDCKDGSDEKNCSARN-CRPDQFKCDDGSCIHGSRQCNGFRDCVDGTDE 305

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Zebrafish
Match: vldlr (very low density lipoprotein receptor [Source:ZFIN;Acc:ZDB-GENE-040426-803])

HSP 1 Score: 197.208 bits (500), Expect = 1.018e-52
Identity = 137/484 (28.31%), Postives = 227/484 (46.90%), Query Frame = 1

Query:  106 KCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKA-KEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLS----AFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYF-HPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            KC   +  CG     +CI + W CD + DC D SDE NC    C  +QFKC D   CI   + C+G  DC++  DE NC N+  CN    + C   +  ECI++  +CN   +C    D  ++ C  + C  +   CSHIC +    F CDC P ++L  D + C  +N+C  NP +C Q C +    Y C C++GY        PTT   +               I  L    +   +I     +  +LD +  + +M+F++ L  K                    S++ +KQ+ E + K +         A+D     ++++D    SI V N     K  + +     P +I +DP+ G L+W D G      KI+ + M+G+ +  L+E +I+ P  + +D+ + RLYW D     +  +D+N  ++  +    + + +Y  HPF++ +F +R++W+D +   IY A+K TG DV ++
Sbjct:  234 KCSPSEMQCGSG---ECIHRKWRCDGDPDCKDGSDEKNCSARNCRPDQFKCDDGS-CIHGSRQCNGFRDCVDGTDEVNCKNLTQCNSSDQFKC---RSGECIEMSKVCNKVRDCPDWSDEPIKECNMNECLINNGGCSHICRDLTIGFECDCTPGLQLI-DRKTCGDVNECL-NPGICSQICINLKGGYKCECHNGYQMD-----PTTGVCKAVGKEPCLIFTNRRDIRKLGLERREYTQIVEQLRNTVALDADFIQ-QMIFWADLGQK-----------------AIFSTVLDKQD-ESHKKVIDDVQMPVGIAVDWIYKNIYWSDLGSKSITVANFNGTKKKVLFNSGLKEPASIAVDPLSGFLYWSDWGEP---AKIEKSGMNGNDRQVLVETDIQWPNGITLDLIKGRLYWVDSKLHMLCSVDLNGDNRRKV----LQSPDYLAHPFALTVFEDRVFWTDGENEAIYGANKFTGSDVTLL 677

HSP 2 Score: 65.855 bits (159), Expect = 1.238e-10
Identity = 55/183 (30.05%), Postives = 82/183 (44.81%), Query Frame = 1

Query:   76 ICLNFY----ACHFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKT----HYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHI-CINKYSSFTCDCPPDMELSEDNRNC 597
            +C   +    A   +C Q    CG     +CI  +W CD + DC D SDE +C    C +  F C  S  CIP+   CDG  DC +  DE    +I  C+ +T     ++CG     +CI +   C+   +C   +D + NC    C   E TCS   C+++   F C+   D     D ++C
Sbjct:   14 VCFQLWGFSRASRAECEQSQFQCGNG---RCIPSVWQCDGDMDCSDGSDETSCVRKTCAEVDFVC-RSGQCIPKRWQCDGEPDCEDGSDE----SIEMCHTRTCRVNEFSCG-VGSTQCIPVFWKCDGEKDCDNGEDEI-NCGNITCAPLEFTCSSGRCVSR--KFVCNGEDDCGDGSDEQDC 184

HSP 3 Score: 62.3882 bits (150), Expect = 1.855e-9
Identity = 67/212 (31.60%), Postives = 97/212 (45.75%), Query Frame = 1

Query:   97 CHFK-CLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDI-CNTNINCSTNKDSLENCKAD-----FCKTSENTC-SHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQG-CQDNGKSYNCF--CYDGYTE 699
            CH + C  ++  CG  S  QCI   W CD  +DCD+  DE+NC  + C   +F C  S  C+ R+ +C+G +DC +  DE +C   +SC+  +   CGN     CI    +  +       + +S E C  +      C  SE  C S  CI++   + CD  PD +   D +NC   N C  +   C  G C    +  N F  C DG  E
Sbjct:  104 CHTRTCRVNEFSCGVGST-QCIPVFWKCDGEKDCDNGEDEINCGNITCAPLEFTC-SSGRCVSRKFVCNGEDDCGDGSDEQDCAP-SSCS-PSEIPCGNNT---CIPRSWLCDDDVDCQDQSDESPERCGHNPTPPAKCSPSEMQCGSGECIHR--KWRCDGDPDCKDGSDEKNCSARN-CRPDQFKCDDGSCIHGSRQCNGFRDCVDGTDE 305

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Zebrafish
Match: vldlr (very low density lipoprotein receptor [Source:ZFIN;Acc:ZDB-GENE-040426-803])

HSP 1 Score: 197.208 bits (500), Expect = 1.050e-52
Identity = 137/484 (28.31%), Postives = 227/484 (46.90%), Query Frame = 1

Query:  106 KCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKA-KEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLS----AFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYF-HPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            KC   +  CG     +CI + W CD + DC D SDE NC    C  +QFKC D   CI   + C+G  DC++  DE NC N+  CN    + C   +  ECI++  +CN   +C    D  ++ C  + C  +   CSHIC +    F CDC P ++L  D + C  +N+C  NP +C Q C +    Y C C++GY        PTT   +               I  L    +   +I     +  +LD +  + +M+F++ L  K                    S++ +KQ+ E + K +         A+D     ++++D    SI V N     K  + +     P +I +DP+ G L+W D G      KI+ + M+G+ +  L+E +I+ P  + +D+ + RLYW D     +  +D+N  ++  +    + + +Y  HPF++ +F +R++W+D +   IY A+K TG DV ++
Sbjct:  234 KCSPSEMQCGSG---ECIHRKWRCDGDPDCKDGSDEKNCSARNCRPDQFKCDDGS-CIHGSRQCNGFRDCVDGTDEVNCKNLTQCNSSDQFKC---RSGECIEMSKVCNKVRDCPDWSDEPIKECNMNECLINNGGCSHICRDLTIGFECDCTPGLQLI-DRKTCGDVNECL-NPGICSQICINLKGGYKCECHNGYQMD-----PTTGVCKAVGKEPCLIFTNRRDIRKLGLERREYTQIVEQLRNTVALDADFIQ-QMIFWADLGQK-----------------AIFSTVLDKQD-ESHKKVIDDVQMPVGIAVDWIYKNIYWSDLGSKSITVANFNGTKKKVLFNSGLKEPASIAVDPLSGFLYWSDWGEP---AKIEKSGMNGNDRQVLVETDIQWPNGITLDLIKGRLYWVDSKLHMLCSVDLNGDNRRKV----LQSPDYLAHPFALTVFEDRVFWTDGENEAIYGANKFTGSDVTLL 677

HSP 2 Score: 65.855 bits (159), Expect = 1.209e-10
Identity = 55/183 (30.05%), Postives = 82/183 (44.81%), Query Frame = 1

Query:   76 ICLNFY----ACHFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKT----HYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHI-CINKYSSFTCDCPPDMELSEDNRNC 597
            +C   +    A   +C Q    CG     +CI  +W CD + DC D SDE +C    C +  F C  S  CIP+   CDG  DC +  DE    +I  C+ +T     ++CG     +CI +   C+   +C   +D + NC    C   E TCS   C+++   F C+   D     D ++C
Sbjct:   14 VCFQLWGFSRASRAECEQSQFQCGNG---RCIPSVWQCDGDMDCSDGSDETSCVRKTCAEVDFVC-RSGQCIPKRWQCDGEPDCEDGSDE----SIEMCHTRTCRVNEFSCG-VGSTQCIPVFWKCDGEKDCDNGEDEI-NCGNITCAPLEFTCSSGRCVSR--KFVCNGEDDCGDGSDEQDC 184

HSP 3 Score: 62.3882 bits (150), Expect = 1.795e-9
Identity = 67/212 (31.60%), Postives = 97/212 (45.75%), Query Frame = 1

Query:   97 CHFK-CLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDI-CNTNINCSTNKDSLENCKAD-----FCKTSENTC-SHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQG-CQDNGKSYNCF--CYDGYTE 699
            CH + C  ++  CG  S  QCI   W CD  +DCD+  DE+NC  + C   +F C  S  C+ R+ +C+G +DC +  DE +C   +SC+  +   CGN     CI    +  +       + +S E C  +      C  SE  C S  CI++   + CD  PD +   D +NC   N C  +   C  G C    +  N F  C DG  E
Sbjct:  104 CHTRTCRVNEFSCGVGST-QCIPVFWKCDGEKDCDNGEDEINCGNITCAPLEFTC-SSGRCVSRKFVCNGEDDCGDGSDEQDCA-PSSCS-PSEIPCGNNT---CIPRSWLCDDDVDCQDQSDESPERCGHNPTPPAKCSPSEMQCGSGECIHR--KWRCDGDPDCKDGSDEKNCSARN-CRPDQFKCDDGSCIHGSRQCNGFRDCVDGTDE 305

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Zebrafish
Match: vldlr (very low density lipoprotein receptor [Source:ZFIN;Acc:ZDB-GENE-040426-803])

HSP 1 Score: 197.208 bits (500), Expect = 1.055e-52
Identity = 137/484 (28.31%), Postives = 227/484 (46.90%), Query Frame = 1

Query:  106 KCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKA-KEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLS----AFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYF-HPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            KC   +  CG     +CI + W CD + DC D SDE NC    C  +QFKC D   CI   + C+G  DC++  DE NC N+  CN    + C   +  ECI++  +CN   +C    D  ++ C  + C  +   CSHIC +    F CDC P ++L  D + C  +N+C  NP +C Q C +    Y C C++GY        PTT   +               I  L    +   +I     +  +LD +  + +M+F++ L  K                    S++ +KQ+ E + K +         A+D     ++++D    SI V N     K  + +     P +I +DP+ G L+W D G      KI+ + M+G+ +  L+E +I+ P  + +D+ + RLYW D     +  +D+N  ++  +    + + +Y  HPF++ +F +R++W+D +   IY A+K TG DV ++
Sbjct:  234 KCSPSEMQCGSG---ECIHRKWRCDGDPDCKDGSDEKNCSARNCRPDQFKCDDGS-CIHGSRQCNGFRDCVDGTDEVNCKNLTQCNSSDQFKC---RSGECIEMSKVCNKVRDCPDWSDEPIKECNMNECLINNGGCSHICRDLTIGFECDCTPGLQLI-DRKTCGDVNECL-NPGICSQICINLKGGYKCECHNGYQMD-----PTTGVCKAVGKEPCLIFTNRRDIRKLGLERREYTQIVEQLRNTVALDADFIQ-QMIFWADLGQK-----------------AIFSTVLDKQD-ESHKKVIDDVQMPVGIAVDWIYKNIYWSDLGSKSITVANFNGTKKKVLFNSGLKEPASIAVDPLSGFLYWSDWGEP---AKIEKSGMNGNDRQVLVETDIQWPNGITLDLIKGRLYWVDSKLHMLCSVDLNGDNRRKV----LQSPDYLAHPFALTVFEDRVFWTDGENEAIYGANKFTGSDVTLL 677

HSP 2 Score: 66.2402 bits (160), Expect = 1.192e-10
Identity = 55/183 (30.05%), Postives = 82/183 (44.81%), Query Frame = 1

Query:   76 ICLNFY----ACHFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKT----HYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHI-CINKYSSFTCDCPPDMELSEDNRNC 597
            +C   +    A   +C Q    CG     +CI  +W CD + DC D SDE +C    C +  F C  S  CIP+   CDG  DC +  DE    +I  C+ +T     ++CG     +CI +   C+   +C   +D + NC    C   E TCS   C+++   F C+   D     D ++C
Sbjct:   14 VCFQLWGFSRASRAECEQSQFQCGNG---RCIPSVWQCDGDMDCSDGSDETSCVRKTCAEVDFVC-RSGQCIPKRWQCDGEPDCEDGSDE----SIEMCHTRTCRVNEFSCG-VGSTQCIPVFWKCDGEKDCDNGEDEI-NCGNITCAPLEFTCSSGRCVSR--KFVCNGEDDCGDGSDEQDC 184

HSP 3 Score: 62.3882 bits (150), Expect = 1.818e-9
Identity = 67/212 (31.60%), Postives = 97/212 (45.75%), Query Frame = 1

Query:   97 CHFK-CLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDI-CNTNINCSTNKDSLENCKAD-----FCKTSENTC-SHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQG-CQDNGKSYNCF--CYDGYTE 699
            CH + C  ++  CG  S  QCI   W CD  +DCD+  DE+NC  + C   +F C  S  C+ R+ +C+G +DC +  DE +C   +SC+  +   CGN     CI    +  +       + +S E C  +      C  SE  C S  CI++   + CD  PD +   D +NC   N C  +   C  G C    +  N F  C DG  E
Sbjct:  104 CHTRTCRVNEFSCGVGST-QCIPVFWKCDGEKDCDNGEDEINCGNITCAPLEFTC-SSGRCVSRKFVCNGEDDCGDGSDEQDCAP-SSCS-PSEIPCGNNT---CIPRSWLCDDDVDCQDQSDESPERCGHNPTPPAKCSPSEMQCGSGECIHR--KWRCDGDPDCKDGSDEKNCSARN-CRPDQFKCDDGSCIHGSRQCNGFRDCVDGTDE 305

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Xenopus
Match: VLDLR (very low density lipoprotein receptor [Source:NCBI gene;Acc:733485])

HSP 1 Score: 199.519 bits (506), Expect = 1.709e-53
Identity = 136/488 (27.87%), Postives = 226/488 (46.31%), Query Frame = 1

Query:  106 KCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMV-----FYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNL----SAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNI-KTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            KC  ++  CG     +CI K W CD + DC D SDE+NCP   C  +QFKC D + CI   + CDGV DC++  DE  C N+N C+    + C   +  ECI I  +CN   +C    D  ++ C  + C+ +   CSH+C N    + CDC    +L  D + C  I++C +NPE+C Q C +    Y C C  GY       V      E  L                        IF  + DI    V L R E +       +++    ++ + S      +   ++ +    ++ +  ++K +    S  + A+D     +++ D    +I V N     +  + +     P +I +DP+ G ++W D G      KI+ A M+G  +   +  ++++P  +AID+ + RLYW D     +  +D+N L +  I K+   LA    HP ++ IF +R+YW D +   IY A+K +G++++ +
Sbjct:  226 KCSANEMPCGSG---ECIHKKWRCDGDPDCKDKSDEMNCPSRTCQPDQFKCEDGN-CIHGSRQCDGVRDCLDGTDEIRCKNVNQCSGPGKFKC---RSGECIDIAKVCNKQKDCKDWSDEPIKECYVNECEVNNGGCSHLCHNLVIGYECDCTAGFKLI-DRKTCGDIDEC-QNPEICSQICVNLKGGYKCECSKGYQMDPSTGVCKAVGKEPCL------------------------IFTNRRDIRK--VGLERKEYIQLVEQLRNTVALDADIKEQSLFWADTIQKAIFRAPFDTREKVGTHIKVVEDVHSPSAIAIDWIYKNIYWMDTGLKTISVSNFDGSKRKTLFNSGLQDPTSIAVDPISGFIYWSDWGEP---AKIEKAGMNGIDRQQFVTADVQRPSGIAIDVVKSRLYWVDSKLHTLSSVDLNGLDRRVILKSHEFLA----HPLALTIFEDRVYWIDGENEAIYGANKFSGQELETL 671

HSP 2 Score: 72.4034 bits (176), Expect = 1.773e-12
Identity = 53/151 (35.10%), Postives = 76/151 (50.33%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDE-WNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHI-CINKYSSFTCDCPPDMELSEDNRNC 597
             CI+ LW CD ++DC D SDE +C    C +  F C ++ LC+PR   CDG  DC +  DE     ++ +C   T  +CG  +  +CI +   C+   +C   +D  ENC    C  +E TCS   CI+  S+F C+   D     D  NC
Sbjct:   32 HCITSLWKCDGDEDCSDGSDESSCVKKTCAETDFVC-NNGLCVPRRWECDGDPDCEDGSDETAELCHMRTC-RATEISCG-ARSTQCIPLSWKCDGESDCPNAEDE-ENCGNITCSPAEFTCSSGRCIS--STFVCNGQNDCSDGSDEENC 176

HSP 3 Score: 67.0106 bits (162), Expect = 7.474e-11
Identity = 59/175 (33.71%), Postives = 81/175 (46.29%), Query Frame = 1

Query:   97 CHFK-CLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKD-SLENC-----KADFCKTSENTC-SHICINKYSSFTCDCPPDMELSEDNRNC 597
            CH + C   +  CG  S  QCI   W CD   DC +  DE NC  + C   +F C  S  CI    +C+G NDC +  DE NC    +C     + C N+    CI +  +C+ + +C+ + D SLE C         C  +E  C S  CI+K   + CD  PD +   D  NC
Sbjct:   96 CHMRTCRATEISCGARST-QCIPLSWKCDGESDCPNAEDEENCGNITCSPAEFTC-SSGRCISSTFVCNGQNDCSDGSDEENCVP-PTCGAH-EFQCKNSS---CIPLNWVCDDDSDCADHSDESLEQCGRQPIAPQKCSANEMPCGSGECIHK--KWRCDGDPDCKDKSDEMNC 261

HSP 4 Score: 63.5438 bits (153), Expect = 1.151e-9
Identity = 52/161 (32.30%), Postives = 76/161 (47.20%), Query Frame = 1

Query:  142 SFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEW--NCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHI-CINKYSSFTCDCPPDMELSEDNRNCKHINKC 615
            S  +CIS  +VC+   DC D SDE NC P  C  ++F+C +S  CIP   +CD  +DC ++ DE    C       +K   N       ECI  +  C+ + +C    D + NC +  C+  +  C    CI  + S  CD   D     D   CK++N+C
Sbjct:  150 SSGRCISSTFVCNGQNDCSDGSDEENCVPPTCGAHEFQCKNSS-CIPLNWVCDDDSDCADHSDESLEQCGRQPIAPQKCSANEMPCGSGECIHKKWRCDGDPDCKDKSDEM-NCPSRTCQPDQFKCEDGNCI--HGSRQCDGVRDCLDGTDEIRCKNVNQC 306

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Xenopus
Match: VLDLR (very low density lipoprotein receptor [Source:NCBI gene;Acc:733485])

HSP 1 Score: 199.519 bits (506), Expect = 2.303e-53
Identity = 135/488 (27.66%), Postives = 227/488 (46.52%), Query Frame = 1

Query:  106 KCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMV-----FYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNL----SAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLS-QLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            KC  ++  CG     +CI K W CD + DC D SDE+NCP   C  +QFKC D + CI   + CDGV DC++  DE  C N+N C+    + C   +  ECI I  +CN   +C    D  ++ C  + C+ +   CSH+C N    + CDC    +L  D + C  I++C +NPE+C Q C +    Y C C  GY       V      E  L                        IF  + DI    V L R E +       +++    ++ + S      +   ++ +    ++ +  ++K +    S  + A+D     +++ D    +I V N     +  + +     P +I +DP+ G ++W D G      KI+ A M+G  +   +  ++++P  +AID+ + RLYW D     +  +D+N L  ++ +K+   LA    HP ++ IF +R+YW D +   IY A+K +G++++ +
Sbjct:  236 KCSANEMPCGSG---ECIHKKWRCDGDPDCKDKSDEMNCPSRTCQPDQFKCEDGN-CIHGSRQCDGVRDCLDGTDEIRCKNVNQCSGPGKFKC---RSGECIDIAKVCNKQKDCKDWSDEPIKECYVNECEVNNGGCSHLCHNLVIGYECDCTAGFKLI-DRKTCGDIDEC-QNPEICSQICVNLKGGYKCECSKGYQMDPSTGVCKAVGKEPCL------------------------IFTNRRDIRK--VGLERKEYIQLVEQLRNTVALDADIKEQSLFWADTIQKAIFRAPFDTREKVGTHIKVVEDVHSPSAIAIDWIYKNIYWMDTGLKTISVSNFDGSKRKTLFNSGLQDPTSIAVDPISGFIYWSDWGEP---AKIEKAGMNGIDRQQFVTADVQRPSGIAIDVVKSRLYWVDSKLHTLSSVDLNGLDRRVILKSHEFLA----HPLALTIFEDRVYWIDGENEAIYGANKFSGQELETL 681

HSP 2 Score: 72.7886 bits (177), Expect = 1.542e-12
Identity = 53/151 (35.10%), Postives = 76/151 (50.33%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDE-WNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHI-CINKYSSFTCDCPPDMELSEDNRNC 597
             CI+ LW CD ++DC D SDE +C    C +  F C ++ LC+PR   CDG  DC +  DE     ++ +C   T  +CG  +  +CI +   C+   +C   +D  ENC    C  +E TCS   CI+  S+F C+   D     D  NC
Sbjct:   42 HCITSLWKCDGDEDCSDGSDESSCVKKTCAETDFVC-NNGLCVPRRWECDGDPDCEDGSDETAELCHMRTC-RATEISCG-ARSTQCIPLSWKCDGESDCPNAEDE-ENCGNITCSPAEFTCSSGRCIS--STFVCNGQNDCSDGSDEENC 186

HSP 3 Score: 67.3958 bits (163), Expect = 6.665e-11
Identity = 59/175 (33.71%), Postives = 81/175 (46.29%), Query Frame = 1

Query:   97 CHFK-CLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKD-SLENC-----KADFCKTSENTC-SHICINKYSSFTCDCPPDMELSEDNRNC 597
            CH + C   +  CG  S  QCI   W CD   DC +  DE NC  + C   +F C  S  CI    +C+G NDC +  DE NC    +C     + C N+    CI +  +C+ + +C+ + D SLE C         C  +E  C S  CI+K   + CD  PD +   D  NC
Sbjct:  106 CHMRTCRATEISCGARST-QCIPLSWKCDGESDCPNAEDEENCGNITCSPAEFTC-SSGRCISSTFVCNGQNDCSDGSDEENCVP-PTCGAH-EFQCKNSS---CIPLNWVCDDDSDCADHSDESLEQCGRQPIAPQKCSANEMPCGSGECIHK--KWRCDGDPDCKDKSDEMNC 271

HSP 4 Score: 63.5438 bits (153), Expect = 1.034e-9
Identity = 52/161 (32.30%), Postives = 76/161 (47.20%), Query Frame = 1

Query:  142 SFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEW--NCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHI-CINKYSSFTCDCPPDMELSEDNRNCKHINKC 615
            S  +CIS  +VC+   DC D SDE NC P  C  ++F+C +S  CIP   +CD  +DC ++ DE    C       +K   N       ECI  +  C+ + +C    D + NC +  C+  +  C    CI  + S  CD   D     D   CK++N+C
Sbjct:  160 SSGRCISSTFVCNGQNDCSDGSDEENCVPPTCGAHEFQCKNSS-CIPLNWVCDDDSDCADHSDESLEQCGRQPIAPQKCSANEMPCGSGECIHKKWRCDGDPDCKDKSDEM-NCPSRTCQPDQFKCEDGNCI--HGSRQCDGVRDCLDGTDEIRCKNVNQC 316

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Xenopus
Match: VLDLR (very low density lipoprotein receptor [Source:NCBI gene;Acc:733485])

HSP 1 Score: 199.134 bits (505), Expect = 2.511e-53
Identity = 135/480 (28.12%), Postives = 229/480 (47.71%), Query Frame = 1

Query:  106 KCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAK-EIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLS-QLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            KC  ++  CG     +CI K W CD + DC D SDE+NCP   C  +QFKC D + CI   + CDGV DC++  DE  C N+N C+    + C   +  ECI I  +CN   +C    D  ++ C  + C+ +   CSH+C N    + CDC    +L  D + C  I++C +NPE+C Q C +    Y C C  GY        P+T   +               I  +    K   ++     +  +LD ++ + + +F++  + K     V  LQ          S++     +  ++ + SA   A+D     +++ D    +I V N     +  + +     P +I +DP+ G ++W D G      KI+ A M+G  +   +  ++++P  +AID+ + RLYW D     +  +D+N L  ++ +K+   LA    HP ++ IF +R+YW D +   IY A+K +G++++ +
Sbjct:  236 KCSANEMPCGSG---ECIHKKWRCDGDPDCKDKSDEMNCPSRTCQPDQFKCEDGN-CIHGSRQCDGVRDCLDGTDEIRCKNVNQCSGPGKFKC---RSGECIDIAKVCNKQKDCKDWSDEPIKECYVNECEVNNGGCSHLCHNLVIGYECDCTAGFKLI-DRKTCGDIDEC-QNPEICSQICVNLKGGYKCECSKGYQMD-----PSTGVCKAVGKEPCLIFTNRRDIRKVGLERKEYIQLVEQLRNTVALDADI-KEQSLFWADTIQKAIFRFVIYLQ---------FSNLCTHIKVVEDVHSPSAI--AIDWIYKNIYWMDTGLKTISVSNFDGSKRKTLFNSGLQDPTSIAVDPISGFIYWSDWGEP---AKIEKAGMNGIDRQQFVTADVQRPSGIAIDVVKSRLYWVDSKLHTLSSVDLNGLDRRVILKSHEFLA----HPLALTIFEDRVYWIDGENEAIYGANKFSGQELETL 682

HSP 2 Score: 72.4034 bits (176), Expect = 1.856e-12
Identity = 53/151 (35.10%), Postives = 76/151 (50.33%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDE-WNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHI-CINKYSSFTCDCPPDMELSEDNRNC 597
             CI+ LW CD ++DC D SDE +C    C +  F C ++ LC+PR   CDG  DC +  DE     ++ +C   T  +CG  +  +CI +   C+   +C   +D  ENC    C  +E TCS   CI+  S+F C+   D     D  NC
Sbjct:   42 HCITSLWKCDGDEDCSDGSDESSCVKKTCAETDFVC-NNGLCVPRRWECDGDPDCEDGSDETAELCHMRTC-RATEISCG-ARSTQCIPLSWKCDGESDCPNAEDE-ENCGNITCSPAEFTCSSGRCIS--STFVCNGQNDCSDGSDEENC 186

HSP 3 Score: 63.1586 bits (152), Expect = 1.224e-9
Identity = 52/161 (32.30%), Postives = 76/161 (47.20%), Query Frame = 1

Query:  142 SFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEW--NCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHI-CINKYSSFTCDCPPDMELSEDNRNCKHINKC 615
            S  +CIS  +VC+   DC D SDE NC P  C  ++F+C +S  CIP   +CD  +DC ++ DE    C       +K   N       ECI  +  C+ + +C    D + NC +  C+  +  C    CI  + S  CD   D     D   CK++N+C
Sbjct:  160 SSGRCISSTFVCNGQNDCSDGSDEENCVPPTCGAHEFQCKNSS-CIPLNWVCDDDSDCADHSDESLEQCGRQPIAPQKCSANEMPCGSGECIHKKWRCDGDPDCKDKSDEM-NCPSRTCQPDQFKCEDGNCI--HGSRQCDGVRDCLDGTDEIRCKNVNQC 316

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Xenopus
Match: VLDLR (very low density lipoprotein receptor [Source:NCBI gene;Acc:733485])

HSP 1 Score: 199.134 bits (505), Expect = 2.592e-53
Identity = 136/488 (27.87%), Postives = 226/488 (46.31%), Query Frame = 1

Query:  106 KCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMV-----FYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNL----SAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNI-KTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            KC  ++  CG     +CI K W CD + DC D SDE+NCP   C  +QFKC D + CI   + CDGV DC++  DE  C N+N C+    + C   +  ECI I  +CN   +C    D  ++ C  + C+ +   CSH+C N    + CDC    +L  D + C  I++C +NPE+C Q C +    Y C C  GY       V      E  L                        IF  + DI    V L R E +       +++    ++ + S      +   ++ +    ++ +  ++K +    S  + A+D     +++ D    +I V N     +  + +     P +I +DP+ G ++W D G      KI+ A M+G  +   +  ++++P  +AID+ + RLYW D     +  +D+N L +  I K+   LA    HP ++ IF +R+YW D +   IY A+K +G++++ +
Sbjct:  215 KCSANEMPCGSG---ECIHKKWRCDGDPDCKDKSDEMNCPSRTCQPDQFKCEDGN-CIHGSRQCDGVRDCLDGTDEIRCKNVNQCSGPGKFKC---RSGECIDIAKVCNKQKDCKDWSDEPIKECYVNECEVNNGGCSHLCHNLVIGYECDCTAGFKLI-DRKTCGDIDEC-QNPEICSQICVNLKGGYKCECSKGYQMDPSTGVCKAVGKEPCL------------------------IFTNRRDIRK--VGLERKEYIQLVEQLRNTVALDADIKEQSLFWADTIQKAIFRAPFDTREKVGTHIKVVEDVHSPSAIAIDWIYKNIYWMDTGLKTISVSNFDGSKRKTLFNSGLQDPTSIAVDPISGFIYWSDWGEP---AKIEKAGMNGIDRQQFVTADVQRPSGIAIDVVKSRLYWVDSKLHTLSSVDLNGLDRRVILKSHEFLA----HPLALTIFEDRVYWIDGENEAIYGANKFSGQELETL 660

HSP 2 Score: 72.4034 bits (176), Expect = 1.776e-12
Identity = 53/151 (35.10%), Postives = 76/151 (50.33%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDE-WNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHI-CINKYSSFTCDCPPDMELSEDNRNC 597
             CI+ LW CD ++DC D SDE +C    C +  F C ++ LC+PR   CDG  DC +  DE     ++ +C   T  +CG  +  +CI +   C+   +C   +D  ENC    C  +E TCS   CI+  S+F C+   D     D  NC
Sbjct:   21 HCITSLWKCDGDEDCSDGSDESSCVKKTCAETDFVC-NNGLCVPRRWECDGDPDCEDGSDETAELCHMRTC-RATEISCG-ARSTQCIPLSWKCDGESDCPNAEDE-ENCGNITCSPAEFTCSSGRCIS--STFVCNGQNDCSDGSDEENC 165

HSP 3 Score: 67.0106 bits (162), Expect = 8.509e-11
Identity = 59/175 (33.71%), Postives = 81/175 (46.29%), Query Frame = 1

Query:   97 CHFK-CLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKD-SLENC-----KADFCKTSENTC-SHICINKYSSFTCDCPPDMELSEDNRNC 597
            CH + C   +  CG  S  QCI   W CD   DC +  DE NC  + C   +F C  S  CI    +C+G NDC +  DE NC    +C     + C N+    CI +  +C+ + +C+ + D SLE C         C  +E  C S  CI+K   + CD  PD +   D  NC
Sbjct:   85 CHMRTCRATEISCGARST-QCIPLSWKCDGESDCPNAEDEENCGNITCSPAEFTC-SSGRCISSTFVCNGQNDCSDGSDEENCVP-PTCGAH-EFQCKNSS---CIPLNWVCDDDSDCADHSDESLEQCGRQPIAPQKCSANEMPCGSGECIHK--KWRCDGDPDCKDKSDEMNC 250

HSP 4 Score: 63.1586 bits (152), Expect = 1.192e-9
Identity = 52/161 (32.30%), Postives = 76/161 (47.20%), Query Frame = 1

Query:  142 SFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEW--NCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHI-CINKYSSFTCDCPPDMELSEDNRNCKHINKC 615
            S  +CIS  +VC+   DC D SDE NC P  C  ++F+C +S  CIP   +CD  +DC ++ DE    C       +K   N       ECI  +  C+ + +C    D + NC +  C+  +  C    CI  + S  CD   D     D   CK++N+C
Sbjct:  139 SSGRCISSTFVCNGQNDCSDGSDEENCVPPTCGAHEFQCKNSS-CIPLNWVCDDDSDCADHSDESLEQCGRQPIAPQKCSANEMPCGSGECIHKKWRCDGDPDCKDKSDEM-NCPSRTCQPDQFKCEDGNCI--HGSRQCDGVRDCLDGTDEIRCKNVNQC 295

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Xenopus
Match: VLDLR (very low density lipoprotein receptor [Source:NCBI gene;Acc:733485])

HSP 1 Score: 199.519 bits (506), Expect = 2.662e-53
Identity = 136/488 (27.87%), Postives = 226/488 (46.31%), Query Frame = 1

Query:  106 KCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMV-----FYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNL----SAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNI-KTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            KC  ++  CG     +CI K W CD + DC D SDE+NCP   C  +QFKC D + CI   + CDGV DC++  DE  C N+N C+    + C   +  ECI I  +CN   +C    D  ++ C  + C+ +   CSH+C N    + CDC    +L  D + C  I++C +NPE+C Q C +    Y C C  GY       V      E  L                        IF  + DI    V L R E +       +++    ++ + S      +   ++ +    ++ +  ++K +    S  + A+D     +++ D    +I V N     +  + +     P +I +DP+ G ++W D G      KI+ A M+G  +   +  ++++P  +AID+ + RLYW D     +  +D+N L +  I K+   LA    HP ++ IF +R+YW D +   IY A+K +G++++ +
Sbjct:  236 KCSANEMPCGSG---ECIHKKWRCDGDPDCKDKSDEMNCPSRTCQPDQFKCEDGN-CIHGSRQCDGVRDCLDGTDEIRCKNVNQCSGPGKFKC---RSGECIDIAKVCNKQKDCKDWSDEPIKECYVNECEVNNGGCSHLCHNLVIGYECDCTAGFKLI-DRKTCGDIDEC-QNPEICSQICVNLKGGYKCECSKGYQMDPSTGVCKAVGREPCL------------------------IFTNRRDIRK--VGLERKEYIQLVEQLRNTVALDADIKEQSLFWADTIQKAIFRAPFDTREKVGTHIKVVEDVHSPSAIAIDWIYKNIYWMDTGLKTISVSNFDGSKRKTLFNSGLQDPTSIAVDPISGFIYWSDWGEP---AKIEKAGMNGIDRQQFVTADVQRPSGIAIDVVKSRLYWVDSKLHTLSSVDLNGLDRRVILKSHEFLA----HPLALTIFEDRVYWIDGENEAIYGANKFSGQELETL 681

HSP 2 Score: 72.7886 bits (177), Expect = 1.579e-12
Identity = 53/151 (35.10%), Postives = 76/151 (50.33%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDE-WNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHI-CINKYSSFTCDCPPDMELSEDNRNC 597
             CI+ LW CD ++DC D SDE +C    C +  F C ++ LC+PR   CDG  DC +  DE     ++ +C   T  +CG  +  +CI +   C+   +C   +D  ENC    C  +E TCS   CI+  S+F C+   D     D  NC
Sbjct:   42 HCITSLWKCDGDEDCSDGSDESSCVKKTCAETDFVC-NNGLCVPRRWECDGDPDCEDGSDETAELCHMRTC-RATEISCG-ARSTQCIPLSWKCDGESDCPNAEDE-ENCGNITCSPAEFTCSSGRCIS--STFVCNGQNDCSDGSDEENC 186

HSP 3 Score: 63.5438 bits (153), Expect = 9.285e-10
Identity = 52/161 (32.30%), Postives = 76/161 (47.20%), Query Frame = 1

Query:  142 SFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEW--NCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHI-CINKYSSFTCDCPPDMELSEDNRNCKHINKC 615
            S  +CIS  +VC+   DC D SDE NC P  C  ++F+C +S  CIP   +CD  +DC ++ DE    C       +K   N       ECI  +  C+ + +C    D + NC +  C+  +  C    CI  + S  CD   D     D   CK++N+C
Sbjct:  160 SSGRCISSTFVCNGQNDCSDGSDEENCVPPTCGAHEFQCKNSS-CIPLNWVCDDDSDCADHSDESLEQCGRQPIAPQKCSANEMPCGSGECIHKKWRCDGDPDCKDKSDEM-NCPSRTCQPDQFKCEDGNCI--HGSRQCDGVRDCLDGTDEIRCKNVNQC 316

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Mouse
Match: Vldlr (very low density lipoprotein receptor [Source:MGI Symbol;Acc:MGI:98935])

HSP 1 Score: 193.356 bits (490), Expect = 1.492e-51
Identity = 140/492 (28.46%), Postives = 223/492 (45.33%), Query Frame = 1

Query:  100 HFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTE--HDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDL-----YLSSISNK--QNIEM--NLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLS-QLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            H KC   +  CG     +CI K W CD + DC D SDEVNCP   C  +QF+C D   CI   + C+G+ DC++  DE NC N+N C     + C   +  ECI +  +C+   +C    D  L+ C  + C  +   CSHIC +    + CDC    EL  D + C  I++C +NP +C Q C +    Y C C  GY        C    +E  +                          IF  + DI    + L R E +     +     L            DL     + +SI +K  ++ +M  N+ N +A   A+D     +++TD    +I V  L    +  + + D   P +I +DP+ G ++W D G      KI+ A M+G  +  L+ ++I+ P  + +D+ + RLYW D     +  +D+N    ++ +K+   LA    HP ++ IF +R+YW D +   +Y A+K TG ++  +
Sbjct:  195 HTKCPTSEIQCGSG---ECIHKKWRCDGDPDCKDGSDEVNCPSRTCRPDQFECEDGS-CIHGSRQCNGIRDCVDGSDEVNCKNVNQCLGPGKFKC---RSGECIDMSKVCDQEQDCRDWSDEPLKECHINECLVNNGGCSHICKDLVIGYECDCAAGFELI-DRKTCGDIDEC-QNPGICSQICINLKGGYKCECSRGYQMDLATGVCKAVGKEPSL--------------------------IFTNRRDIRK--IGLERKEYIQLVEQLRNTVALDADIAAQKLFWADLSQKAIFSASIDDKVGRHFKMIDNVYNPAAI--AVDWVYKTIYWTDAASKTISVATLDGAKRKFLFNSDLREPASIAVDPLSGFVYWSDWGEP---AKIEKAGMNGFDRRPLVTEDIQWPNGITLDLVKSRLYWLDSKLHMLSSVDLNGQDRRIVLKSLEFLA----HPLALTIFEDRVYWIDGENEAVYGANKFTGSELATL 640

HSP 2 Score: 60.4622 bits (145), Expect = 6.181e-9
Identity = 51/173 (29.48%), Postives = 75/173 (43.35%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEW--NCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNC-----KHINKCFKNPEVCHQGC 648
            +CI+ LW CD ++DC D SDE NC    C ++ F C +   C+P    CDG  DC +  DE    C NI        + C + +   C+    +CN   +C    D L+ C    C   E  CS          T  C P   + +D+ +C     + + +C + P V H  C
Sbjct:   44 RCITLLWKCDGDEDCADGSDEKNCVKKTCAESDFVCKNGQ-CVPNRWQCDGDPDCEDGSDESPEQCRNITC--SADEFTCSSGR---CVSRNFVCNGQDDCDDGSDELD-CAPPTCGAHEFQCS----------TSSCIPLSWVCDDDADCSDQSDESLEQCGRQP-VIHTKC 198

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Mouse
Match: Vldlr (very low density lipoprotein receptor [Source:MGI Symbol;Acc:MGI:98935])

HSP 1 Score: 192.971 bits (489), Expect = 2.535e-51
Identity = 140/492 (28.46%), Postives = 223/492 (45.33%), Query Frame = 1

Query:  100 HFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTE--HDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDL-----YLSSISNK--QNIEM--NLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLS-QLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            H KC   +  CG     +CI K W CD + DC D SDEVNCP   C  +QF+C D   CI   + C+G+ DC++  DE NC N+N C     + C   +  ECI +  +C+   +C    D  L+ C  + C  +   CSHIC +    + CDC    EL  D + C  I++C +NP +C Q C +    Y C C  GY        C    +E  +                          IF  + DI    + L R E +     +     L            DL     + +SI +K  ++ +M  N+ N +A   A+D     +++TD    +I V  L    +  + + D   P +I +DP+ G ++W D G      KI+ A M+G  +  L+ ++I+ P  + +D+ + RLYW D     +  +D+N    ++ +K+   LA    HP ++ IF +R+YW D +   +Y A+K TG ++  +
Sbjct:  236 HTKCPTSEIQCGSG---ECIHKKWRCDGDPDCKDGSDEVNCPSRTCRPDQFECEDGS-CIHGSRQCNGIRDCVDGSDEVNCKNVNQCLGPGKFKC---RSGECIDMSKVCDQEQDCRDWSDEPLKECHINECLVNNGGCSHICKDLVIGYECDCAAGFELI-DRKTCGDIDEC-QNPGICSQICINLKGGYKCECSRGYQMDLATGVCKAVGKEPSL--------------------------IFTNRRDIRK--IGLERKEYIQLVEQLRNTVALDADIAAQKLFWADLSQKAIFSASIDDKVGRHFKMIDNVYNPAAI--AVDWVYKTIYWTDAASKTISVATLDGAKRKFLFNSDLREPASIAVDPLSGFVYWSDWGEP---AKIEKAGMNGFDRRPLVTEDIQWPNGITLDLVKSRLYWLDSKLHMLSSVDLNGQDRRIVLKSLEFLA----HPLALTIFEDRVYWIDGENEAVYGANKFTGSELATL 681

HSP 2 Score: 64.3142 bits (155), Expect = 4.871e-10
Identity = 49/154 (31.82%), Postives = 75/154 (48.70%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKT----HYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHI-CINKYSSFTCDCPPDMELSEDNRNC 597
            +CI+ LW CD ++DC D SDE NC    C ++ F C +   C+P    CDG  DC +  DE    +   C+ +T      +CG  +  +CI +   C+   +C   +D  ENC    C   E TCS   C+++  +F C+   D +   D  +C
Sbjct:   44 RCITLLWKCDGDEDCADGSDEKNCVKKTCAESDFVCKNGQ-CVPNRWQCDGDPDCEDGSDE----SPEQCHMRTCRINEISCG-ARSTQCIPVSWRCDGENDCDNGEDE-ENCGNITCSADEFTCSSGRCVSR--NFVCNGQDDCDDGSDELDC 188

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Mouse
Match: Vldlr (very low density lipoprotein receptor [Source:MGI Symbol;Acc:MGI:98935])

HSP 1 Score: 193.356 bits (490), Expect = 2.757e-51
Identity = 140/492 (28.46%), Postives = 223/492 (45.33%), Query Frame = 1

Query:  100 HFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTE--HDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDL-----YLSSISNK--QNIEM--NLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLS-QLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            H KC   +  CG     +CI K W CD + DC D SDEVNCP   C  +QF+C D   CI   + C+G+ DC++  DE NC N+N C     + C   +  ECI +  +C+   +C    D  L+ C  + C  +   CSHIC +    + CDC    EL  D + C  I++C +NP +C Q C +    Y C C  GY        C    +E  +                          IF  + DI    + L R E +     +     L            DL     + +SI +K  ++ +M  N+ N +A   A+D     +++TD    +I V  L    +  + + D   P +I +DP+ G ++W D G      KI+ A M+G  +  L+ ++I+ P  + +D+ + RLYW D     +  +D+N    ++ +K+   LA    HP ++ IF +R+YW D +   +Y A+K TG ++  +
Sbjct:  236 HTKCPTSEIQCGSG---ECIHKKWRCDGDPDCKDGSDEVNCPSRTCRPDQFECEDGS-CIHGSRQCNGIRDCVDGSDEVNCKNVNQCLGPGKFKC---RSGECIDMSKVCDQEQDCRDWSDEPLKECHINECLVNNGGCSHICKDLVIGYECDCAAGFELI-DRKTCGDIDEC-QNPGICSQICINLKGGYKCECSRGYQMDLATGVCKAVGKEPSL--------------------------IFTNRRDIRK--IGLERKEYIQLVEQLRNTVALDADIAAQKLFWADLSQKAIFSASIDDKVGRHFKMIDNVYNPAAI--AVDWVYKTIYWTDAASKTISVATLDGAKRKFLFNSDLREPASIAVDPLSGFVYWSDWGEP---AKIEKAGMNGFDRRPLVTEDIQWPNGITLDLVKSRLYWLDSKLHMLSSVDLNGQDRRIVLKSLEFLA----HPLALTIFEDRVYWIDGENEAVYGANKFTGSELATL 681

HSP 2 Score: 64.3142 bits (155), Expect = 4.090e-10
Identity = 49/154 (31.82%), Postives = 75/154 (48.70%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKT----HYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHI-CINKYSSFTCDCPPDMELSEDNRNC 597
            +CI+ LW CD ++DC D SDE NC    C ++ F C +   C+P    CDG  DC +  DE    +   C+ +T      +CG  +  +CI +   C+   +C   +D  ENC    C   E TCS   C+++  +F C+   D +   D  +C
Sbjct:   44 RCITLLWKCDGDEDCADGSDEKNCVKKTCAESDFVCKNGQ-CVPNRWQCDGDPDCEDGSDE----SPEQCHMRTCRINEISCG-ARSTQCIPVSWRCDGENDCDNGEDE-ENCGNITCSADEFTCSSGRCVSR--NFVCNGQDDCDDGSDELDC 188

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Mouse
Match: Lrp4 (low density lipoprotein receptor-related protein 4 [Source:MGI Symbol;Acc:MGI:2442252])

HSP 1 Score: 181.03 bits (458), Expect = 1.005e-46
Identity = 130/484 (26.86%), Postives = 222/484 (45.87%), Query Frame = 1

Query:  154 CISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCN-EKTHYNCGNTKKLECIKIEDICNTNINC--STNKDSLENCKA----DFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQ-DDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIE--MNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKRVK-PINLRII 1572
            CI+  W CD + DCDD SDE NC   +C   QF+C  S  C+     CDG +DC +N DE NC N  S       + C N +   CI    +CN   +C  S+++   +NC+     + C  +   C+  C     +  C C     L+ED R C+ +N+C +    C QGC +   ++ C+C  GY     +  P     +             + I  + PH     +     ++  +LD + +R E+VF+S +                  +D  L +  N  N+E  ++    S    A+D   + L++TD   S I V NL    +  ++ +    P  I + P+ G ++W D GN    P+I+ ++MDGS +  + +  +  P  L ID   +R+YW D     I+  +++   +      +V++    HPF+I +F + +YW+D     I SA+K TGK+ ++I  ++  P+++  +
Sbjct:  243 CINSGWRCDGDADCDDQSDERNCTTSMCTAEQFRC-RSGRCVRLSWRCDGEDDCADNSDEENCENTGSPQCASDQFLCWNGR---CIGQRKLCNGINDCGDSSDESPQQNCRPRTGEENCNVNNGGCAQKCQMVRGAVQCTCHTGYRLTEDGRTCQDVNECAEE-GYCSQGCTNTEGAFQCWCEAGY-----ELRPDRRSCKALGPEPVLLFANRIDIRQVLPHRSEYTLLLNNLENAIALDFH-HRRELVFWSDVT-----------------LDRILRANLNGSNVEEVVSTGLESPGGLAVDWVHDKLYWTDSGTSRIEVANLDGAHRKVLLWQSLEKPRAIALHPMEGTIYWTDWGNT---PRIEASSMDGSGRRIIADTHLFWPNGLTIDYAGRRMYWVDAKHHVIERANLDGSHRK-----AVISQGLPHPFAITVFEDSLYWTDWHTKSINSANKFTGKNQEIIRNKLHFPMDIHTL 690

HSP 2 Score: 106.301 bits (264), Expect = 5.772e-23
Identity = 56/192 (29.17%), Postives = 95/192 (49.48%), Query Frame = 1

Query:  976 SNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKRVK 1551
               Q + ++    S    A+D   N L++TD     I V N     +  ++ ++   P +IV++P+ G ++W D G     PKI+ A MD S +  ++   +  P  LAID   QRLYW D   + +K I+   L     K    +  +  HPF + ++G RIYW+D +   I SA ++TG D + + + ++
Sbjct:  804 GTGQEVVVDTSLESPAGLAIDWVTNKLYWTDAGTDRIEVANTDGSMRTVLIWENLDRPRDIVVEPMGGYMYWTDWGAS---PKIERAGMDASSRQVIISSNLTWPNGLAIDYGSQRLYWAD---AGMKTIEFAGLDGSKRKVL--IGSQLPHPFGLTLYGQRIYWTDWQTKSIQSADRLTGLDRETLQENLE 987

HSP 3 Score: 86.6557 bits (213), Expect = 7.034e-17
Identity = 84/368 (22.83%), Postives = 141/368 (38.32%), Query Frame = 1

Query:  490 CKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKRVKPINLRIISKESNRQ 1593
            C +    CSH+C+ + S F+C CP  ++L  D +       C  +PE           +Y  F   G                                 + + H        G +++ SLD +        +  + + D  L V +        DL  S++     I   LK       A+D     L++TD   ++I    L    +  +++     P  I + P  G LFW D G+     KI+ AN+DGS +  L+  ++  P  L +D + +R+YW D     I+  D+N       K   VL     HPF++      IYW+D +   I    K +G++ + +   V+ + + II     RQ
Sbjct: 1313 CGSRNGGCSHLCLPRPSGFSCACPTGIQLKGDRKT------CDPSPE-----------TYLLFSSRGSIRR--------------------------ISLDTDDHTDVHVPVPGLNNVISLDYD------SVHGKVYYTDVFLDVIR------RADLNGSNMETV--IGHGLKTTDGL--AVDWVARNLYWTDTGRNTIEASRLDGSCRKVLINNSLDEPRAIAVFPRKGYLFWTDWGHI---AKIERANLDGSERKVLINTDLGWPNGLTLDYDTRRIYWVDAHLDRIESADLNG------KLRQVLVSHVSHPFALTQQDRWIYWTDWQTKSIQRVDKYSGRNKETVLANVEGL-MDIIVVSPQRQ 1611

HSP 4 Score: 77.7962 bits (190), Expect = 3.561e-14
Identity = 47/169 (27.81%), Postives = 81/169 (47.93%), Query Frame = 1

Query: 1030 ALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            A+D     +++TD   + I V NL    +  +V ++   P  IV+   MG ++W D G EN   K++ + MDGS +  L+   +  P  L +D    +L W D     I+  D+N  ++        L     HP+ + +  + IYW+D +   I+ A K TG +V ++
Sbjct: 1130 AVDAIGRKVYWTDTGTNRIEVGNLDGSMRKVLVWQNLDSPRAIVLYHEMGFMYWTDWG-EN--AKLERSGMDGSDRTVLINNNLGWPNGLTVDKTSSQLLWADAHTERIEVADLNGANR------HTLVSPVQHPYGLTLLDSYIYWTDWQTRSIHRADKSTGSNVILV 1289

HSP 5 Score: 65.4698 bits (158), Expect = 2.368e-10
Identity = 40/111 (36.04%), Postives = 63/111 (56.76%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKA 483
            +CI + WVCD + DC+D+SDE +CPP  C++++F C +   CI     CDG NDC +N DE  C ++  C++K  + C +     CI     C+ + +C    D  E+C +
Sbjct:   82 KCIRRSWVCDGDNDCEDDSDEQDCPPRECEEDEFPCQNG-YCIRSLWHCDGDNDCGDNSDE-QC-DMRKCSDK-EFRCSDGS---CIAEHWYCDGDTDCKDGSDE-ESCPS 184

HSP 6 Score: 61.6178 bits (148), Expect = 3.483e-9
Identity = 57/183 (31.15%), Postives = 79/183 (43.17%), Query Frame = 1

Query:   79 CLNFYACHFKCLQDDHYCGKNSFF---------QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCS-HICINKYSSFTCDCPPDMELSEDNRNC 597
            C +  A   +C      CG++ F           CI   W CD + DC D+SDE  C    C    F C D+  CI R  +CDG NDC ++ DE +C     C E+  + C N     CI+    C+ + +C  N D  E C    C   E  CS   CI ++  + CD   D +   D  +C
Sbjct:   15 CAHGIASSLECA-----CGRSHFTCAVSALGECTCIPAQWQCDGDNDCGDHSDEDGCTLPTCSPLDFHC-DNGKCIRRSWVCDGDNDCEDDSDEQDCPP-REC-EEDEFPCQNGY---CIRSLWHCDGDNDCGDNSD--EQCDMRKCSDKEFRCSDGSCIAEH--WYCDGDTDCKDGSDEESC 182

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Mouse
Match: Ldlr (low density lipoprotein receptor [Source:MGI Symbol;Acc:MGI:96765])

HSP 1 Score: 177.178 bits (448), Expect = 5.411e-46
Identity = 131/493 (26.57%), Postives = 222/493 (45.03%), Query Frame = 1

Query:  127 YCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKE--------IFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFS--------------TALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            +CG +   +CI + WVCD   DC D SDE +C    C  ++F+C D   CI   + CD  +DC +  DE  C N+  C+    + C +    ECI ++ +C++  +C    D  ++ CK + C  +   CSHIC +      C CP    L + +R C+ I++C + P+ C Q C +   SY C C  G+                                +++PH +  +        +F  + ++  +   L+R+E   Y+SL+   N+  V  L     N  +Y S +S K+     +      S               A+D     +++TD    S+ V +     +  +  +    P  IV+DPV G ++W D G      KIK   ++G   ++L+ + I+ P  + +D+   RLYW D    +I  ID+N     N KT         HPFS+ I+ +++YW+D+    I+SA+++TG DV ++
Sbjct:  204 HCGSS---ECIHRSWVCDGEADCKDKSDEEHCAVATCRPDEFQCADGS-CIHGSRQCDREHDCKDMSDELGCVNVTQCDGPNKFKCHSG---ECISLDKVCDSARDCQDWSDEPIKECKTNECLDNNGGCSHICKDLKIGSECLCPSGFRLVDLHR-CEDIDEC-QEPDTCSQLCVNLEGSYKCECQAGF--------------------------------HMDPHTRVCKAVGSIGYLLFTNRHEVRKM--TLDRSE---YTSLL--PNLKNVVALDTEVTNNRIYWSDLSQKKIYSALMDQAPNLSYDTIISEDLHAPDGLAVDWIHRNIYWTDSVPGSVSVADTKGVKRRTLFQEAGSRPRAIVVDPVHGFMYWTDWGTP---AKIKKGGLNGVDIHSLVTENIQWPNGITLDLSSGRLYWVDSKLHSISSIDVNGG---NRKTILEDENRLAHPFSLAIYEDKVYWTDVINEAIFSANRLTGSDVNLV 642

HSP 2 Score: 58.9214 bits (141), Expect = 1.778e-8
Identity = 50/150 (33.33%), Postives = 71/150 (47.33%), Query Frame = 1

Query:  130 CGKNSF----FQCISKLWVCDYNQDCDDNSDEV--NCPPMICDKNQFKCPDS-DLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTC-SHICINKYSSFTCD 555
            C +N F     +CI+  WVCD + +C D SDE    C  + C  NQF C      CIP    CDG  DC  + DE  C    +C++   + C + K   CI  + +C+ + +C    D   +C+A  C  +   C S ICI   S + CD
Sbjct:   27 CSRNEFQCRDGKCIASKWVCDGSPECPDGSDESPETCMSVTCQSNQFSCGGRVSRCIPDSWRCDGQVDCENDSDEQGCPP-KTCSQD-DFRCQDGK---CISPQFVCDGDRDCLDGSDEA-HCQATTCGPAHFRCNSSICIP--SLWACD 168

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. UniProt/SwissProt
Match: sp|P98155|VLDLR_HUMAN (Very low-density lipoprotein receptor OS=Homo sapiens OX=9606 GN=VLDLR PE=1 SV=1)

HSP 1 Score: 196.823 bits (499), Expect = 1.044e-51
Identity = 142/492 (28.86%), Postives = 223/492 (45.33%), Query Frame = 1

Query:  100 HFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTE--HDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDL-----YLSSISNK--QNIEM--NLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLS-QLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            H KC   +  CG     +CI K W CD + DC D SDEVNCP   C  +QF+C D   CI   + C+G+ DC++  DE NC N+N C     + C   +  ECI I  +CN   +C    D  L+ C  + C  +   CSHIC +    + CDC    EL  D + C  I++C +NP +C Q C +    Y C C  GY        C    +E  +                          IF  + DI    + L R E +     +     L            DL     + +SI +K  ++++M  N+ N +A   A+D     +++TD    +I V  L    +  + + D   P +I +DP+ G ++W D G      KI+ A M+G  +  L+  +I+ P  + +D+ + RLYW D     +  +D+N    ++ +K+   LA    HP ++ IF +R+YW D +   +Y A+K TG ++  +
Sbjct:  236 HTKCPASEIQCGSG---ECIHKKWRCDGDPDCKDGSDEVNCPSRTCRPDQFECEDGS-CIHGSRQCNGIRDCVDGSDEVNCKNVNQCLGPGKFKC---RSGECIDISKVCNQEQDCRDWSDEPLKECHINECLVNNGGCSHICKDLVIGYECDCAAGFELI-DRKTCGDIDEC-QNPGICSQICINLKGGYKCECSRGYQMDLATGVCKAVGKEPSL--------------------------IFTNRRDIRK--IGLERKEYIQLVEQLRNTVALDADIAAQKLFWADLSQKAIFSASIDDKVGRHVKMIDNVYNPAAI--AVDWVYKTIYWTDAASKTISVATLDGTKRKFLFNSDLREPASIAVDPLSGFVYWSDWGEP---AKIEKAGMNGFDRRPLVTADIQWPNGITLDLIKSRLYWLDSKLHMLSSVDLNGQDRRIVLKSLEFLA----HPLALTIFEDRVYWIDGENEAVYGANKFTGSELATL 681

HSP 2 Score: 62.3882 bits (150), Expect = 1.325e-8
Identity = 50/154 (32.47%), Postives = 75/154 (48.70%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKT----HYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHI-CINKYSSFTCDCPPDMELSEDNRNC 597
            +CI+ LW CD ++DC D SDE NC    C ++ F C ++  C+P    CDG  DC +  DE    +   C+ +T      +CG     +CI +   C+   +C + +D  ENC    C   E TCS   CI++  +F C+   D     D  +C
Sbjct:   44 RCITLLWKCDGDEDCVDGSDEKNCVKKTCAESDFVC-NNGQCVPSRWKCDGDPDCEDGSDE----SPEQCHMRTCRIHEISCG-AHSTQCIPVSWRCDGENDCDSGEDE-ENCGNITCSPDEFTCSSGRCISR--NFVCNGQDDCSDGSDELDC 188

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. UniProt/SwissProt
Match: sp|P35953|VLDLR_RABIT (Very low-density lipoprotein receptor OS=Oryctolagus cuniculus OX=9986 GN=VLDLR PE=2 SV=1)

HSP 1 Score: 196.052 bits (497), Expect = 2.332e-51
Identity = 141/492 (28.66%), Postives = 223/492 (45.33%), Query Frame = 1

Query:  100 HFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTE--HDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVD-----LYLSSISNK--QNIEM--NLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLS-QLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            H KC   +  CG     +CI K W CD + DC D SDEVNCP   C  +QF+C D   CI   + C+G+ DC++  DE NC N+N C     + C   +  ECI I  +CN   +C    D  L+ C  + C  +   CSHIC +    + CDC    EL  D + C  I++C +NP +C Q C +    Y C C  GY        C    +E  +                          IF  + DI    + L R E +     +     L            D     ++ +SI +K  ++++M  N+ N +A   A+D     +++TD    +I V  L    +  + + D   P +I +DP+ G ++W D G      KI+ A M+G  +  L+  +I+ P  + +D+ + RLYW D     +  +D+N    ++ +K+   LA    HP ++ IF +R+YW D +   +Y A+K TG ++  +
Sbjct:  236 HTKCPASEIQCGSG---ECIHKKWRCDGDPDCKDGSDEVNCPSRTCRPDQFECEDGS-CIHGSRQCNGIRDCVDGSDEVNCKNVNQCLGPGKFKC---RSGECIDISKVCNQEQDCRDWSDEPLKECHVNECLVNNGGCSHICKDSVIGYECDCAAGFELI-DRKTCGDIDEC-QNPGICSQICINLKGGYKCECSRGYQMDLATGVCKAVGKEPSL--------------------------IFTNRRDIRK--IGLERKEYIQLVEQLRNTVALDADIAAQKLFWADVSQKAIFSASIDDKVGRHVKMIDNVYNPAAI--AVDWVYKTIYWTDAASRTISVATLDGAKRKFLFNSDLREPASIAVDPLSGFVYWSDWGEP---AKIEKAGMNGFDRRPLVTVDIQWPNGITLDLIKSRLYWLDSKLHMLSSVDLNGQDRRIVLKSLEFLA----HPLALTIFEDRVYWIDGENEAVYGANKFTGSELATL 681

HSP 2 Score: 66.6254 bits (161), Expect = 6.018e-10
Identity = 51/154 (33.12%), Postives = 78/154 (50.65%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKT----HYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHI-CINKYSSFTCDCPPDMELSEDNRNC 597
            +CI++LW CD ++DC D SDE NC    C ++ F C ++  CIP    CDG  DC +  DE    +   C+ +T      +CG  +  +CI +   C+   +C + +D  ENC    C + E TCS   CI++  +F C+   D     D  +C
Sbjct:   44 RCITQLWKCDGDEDCVDGSDEKNCVKKTCAESDFVC-NNGQCIPNRWQCDGDPDCEDGSDE----SPEQCHMRTCRINEISCG-ARSTQCIPVSWRCDGESDCDSGEDE-ENCGNVTCSSDEFTCSSGRCISR--NFVCNGQDDCSDGSDELDC 188

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. UniProt/SwissProt
Match: sp|P98166|VLDLR_RAT (Very low-density lipoprotein receptor OS=Rattus norvegicus OX=10116 GN=Vldlr PE=2 SV=1)

HSP 1 Score: 193.741 bits (491), Expect = 1.250e-50
Identity = 141/492 (28.66%), Postives = 223/492 (45.33%), Query Frame = 1

Query:  100 HFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTE--HDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDL-----YLSSISNK--QNIEM--NLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLS-QLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            H KC   +  CG     +CI K W CD + DC D SDEVNCP   C  +QF+C D   CI   + C+G+ DC++  DE NC N+N C     + C   +  ECI I  +C+   +C    D  L+ C  + C  +   CSHIC +    + CDC    EL  D + C  I++C +NP +C Q C +    Y C C  GY        C    +E  +                          IF  + DI    + L R E +     +     L            DL     + +SI +K  ++ +M  N+ N +A   A+D     +++TD    +I V  L    +  + + D   P +I +DP+ G ++W D G      KI+ A M+G  +  L+ ++I+ P  + +D+ + RLYW D     +  +D+N    ++ +K+   LA    HP ++ IF +R+YW D +   +Y A+K TG ++  +
Sbjct:  236 HTKCPTSEIQCGSG---ECIHKKWRCDGDPDCKDGSDEVNCPSRTCRPDQFECEDGS-CIHGSRQCNGIRDCVDGSDEVNCKNVNQCLGPGKFKC---RSGECIDITKVCDQEQDCRDWSDEPLKECHINECLVNNGGCSHICKDLVIGYECDCAAGFELI-DRKTCGDIDEC-QNPGICSQICINLKGGYKCECSRGYQMDLATGVCKAVGKEPSL--------------------------IFTNRRDIRK--IGLERKEYIQLVEQLRNTVALDADIAAQKLFWADLSQKAIFSASIDDKVGRHFKMIDNVYNPAAI--AVDWVYKTIYWTDAASKTISVATLDGTKRKFLFNSDLREPASIAVDPLSGFVYWSDWGEP---AKIEKAGMNGFDRRPLVTEDIQWPNGITLDLVKSRLYWLDSKLHMLSSVDLNGQDRRIVLKSLEFLA----HPLALTIFEDRVYWIDGENEAVYGANKFTGSELATL 681

HSP 2 Score: 62.003 bits (149), Expect = 1.546e-8
Identity = 49/154 (31.82%), Postives = 74/154 (48.05%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKT----HYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHI-CINKYSSFTCDCPPDMELSEDNRNC 597
            +CI+ LW CD ++DC D SDE NC    C ++ F C +   C+P    CDG  DC +  DE    +   C+ +T      +CG  +  +CI     C+   +C   +D  ENC    C   E TCS   C+++  +F C+   D +   D  +C
Sbjct:   44 RCITLLWKCDGDEDCTDGSDEKNCVKKTCAESDFVCKNGQ-CVPNRWQCDGDPDCEDGSDE----SPEQCHMRTCRINEISCG-ARSTQCIPESWRCDGENDCDNGEDE-ENCGNITCSADEFTCSSGRCVSR--NFVCNGQDDCDDGSDELDC 188

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. UniProt/SwissProt
Match: sp|P98156|VLDLR_MOUSE (Very low-density lipoprotein receptor OS=Mus musculus OX=10090 GN=Vldlr PE=1 SV=1)

HSP 1 Score: 193.356 bits (490), Expect = 1.929e-50
Identity = 140/492 (28.46%), Postives = 223/492 (45.33%), Query Frame = 1

Query:  100 HFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTE--HDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDL-----YLSSISNK--QNIEM--NLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLS-QLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            H KC   +  CG     +CI K W CD + DC D SDEVNCP   C  +QF+C D   CI   + C+G+ DC++  DE NC N+N C     + C   +  ECI +  +C+   +C    D  L+ C  + C  +   CSHIC +    + CDC    EL  D + C  I++C +NP +C Q C +    Y C C  GY        C    +E  +                          IF  + DI    + L R E +     +     L            DL     + +SI +K  ++ +M  N+ N +A   A+D     +++TD    +I V  L    +  + + D   P +I +DP+ G ++W D G      KI+ A M+G  +  L+ ++I+ P  + +D+ + RLYW D     +  +D+N    ++ +K+   LA    HP ++ IF +R+YW D +   +Y A+K TG ++  +
Sbjct:  236 HTKCPTSEIQCGSG---ECIHKKWRCDGDPDCKDGSDEVNCPSRTCRPDQFECEDGS-CIHGSRQCNGIRDCVDGSDEVNCKNVNQCLGPGKFKC---RSGECIDMSKVCDQEQDCRDWSDEPLKECHINECLVNNGGCSHICKDLVIGYECDCAAGFELI-DRKTCGDIDEC-QNPGICSQICINLKGGYKCECSRGYQMDLATGVCKAVGKEPSL--------------------------IFTNRRDIRK--IGLERKEYIQLVEQLRNTVALDADIAAQKLFWADLSQKAIFSASIDDKVGRHFKMIDNVYNPAAI--AVDWVYKTIYWTDAASKTISVATLDGAKRKFLFNSDLREPASIAVDPLSGFVYWSDWGEP---AKIEKAGMNGFDRRPLVTEDIQWPNGITLDLVKSRLYWLDSKLHMLSSVDLNGQDRRIVLKSLEFLA----HPLALTIFEDRVYWIDGENEAVYGANKFTGSELATL 681

HSP 2 Score: 64.3142 bits (155), Expect = 2.861e-9
Identity = 49/154 (31.82%), Postives = 75/154 (48.70%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKT----HYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHI-CINKYSSFTCDCPPDMELSEDNRNC 597
            +CI+ LW CD ++DC D SDE NC    C ++ F C +   C+P    CDG  DC +  DE    +   C+ +T      +CG  +  +CI +   C+   +C   +D  ENC    C   E TCS   C+++  +F C+   D +   D  +C
Sbjct:   44 RCITLLWKCDGDEDCADGSDEKNCVKKTCAESDFVCKNGQ-CVPNRWQCDGDPDCEDGSDE----SPEQCHMRTCRINEISCG-ARSTQCIPVSWRCDGENDCDNGEDE-ENCGNITCSADEFTCSSGRCVSR--NFVCNGQDDCDDGSDELDC 188

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. UniProt/SwissProt
Match: sp|P98165|VLDLR_CHICK (Very low-density lipoprotein receptor OS=Gallus gallus OX=9031 GN=VLDLR PE=1 SV=1)

HSP 1 Score: 192.2 bits (487), Expect = 3.737e-50
Identity = 139/489 (28.43%), Postives = 220/489 (44.99%), Query Frame = 1

Query:  103 FKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVD-----LYLSSISNKQNIEMNLKNL----SAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSL-SQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
             KC   +  CG     +CI K W CD + DC D SDE+NCP   C  +QF+C D + CI   + C+GV DC++  DE NC N+  C+    + C   +  ECI I  +CN + +C    D  L+ C  + C  +   CSHIC +    + CDCP   EL  D R C  I++C +NP +C Q C +    Y C C  GY       V      E  L                        IF  + DI    + L R E +     +     L     +      D     ++ +SI  +  +  + + L    S    A+D     +++TD +  +I V +L    +  +   +   P +I +DP+ G ++W D G      KI+ A M+G  +  L+  EI+ P  +A+D+ + RLYW D     +  +D+N    +L +K+   L     HP ++ IF +R++W D +   +Y A+K TG ++  +
Sbjct:  255 VKCSTSEVQCGSG---ECIHKKWRCDGDPDCKDGSDEINCPSRTCRPDQFRCEDGN-CIHGSRQCNGVRDCLDGTDEANCNNVIQCSGPGKFKC---RSGECIDINKVCNHHGDCKDWSDEPLKECNINECLVNNGGCSHICRDLVIGYECDCPAGFELV-DRRTCGDIDEC-QNPGICSQICINLKGGYKCECSRGYQMDLATGVCKAVGKEPCL------------------------IFTNRRDIRK--IGLERKEYIQLVEQLRNTVALDADIAEQKLYWADFSQKAIFSASIDTRDKVGTHTRILDNIHSPAGIAVDWIYKNIYWTDSSAKTISVASLNGKKRKVLFLSELREPASIAVDPLSGFMYWSDWGEP---AKIEKAGMNGFDRQQLVTTEIQWPNGIALDLVKSRLYWLDSKLHMLSSVDLNGQDRRLVLKSHMFLP----HPLALTIFEDRVFWIDGENEAVYGANKFTGAELVTL 701

HSP 2 Score: 72.4034 bits (176), Expect = 1.036e-11
Identity = 62/175 (35.43%), Postives = 83/175 (47.43%), Query Frame = 1

Query:   97 CHFK-CLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKD-SLENCKAD-----FCKTSENTC-SHICINKYSSFTCDCPPDMELSEDNRNC 597
            CH + C  ++  CG  S  QCI   W CD  +DCD   DE NC  + C   +F C  S  CI +  +C+G +DC +  DE  C    +C     + C   K   CI I  +C+ + +CS + D SLE C         C TSE  C S  CI+K   + CD  PD +   D  NC
Sbjct:  126 CHMRTCRVNEISCGPQST-QCIPVSWKCDGEKDCDSGEDEENCGNVTCSAAEFTC-SSGQCISKSFVCNGQDDCSDGSDELECAP-PTCGVH-EFQC---KSSTCIPISWVCDDDADCSDHSDESLEQCGRQPAPPVKCSTSEVQCGSGECIHK--KWRCDGDPDCKDGSDEINC 291

HSP 3 Score: 66.2402 bits (160), Expect = 8.363e-10
Identity = 52/154 (33.77%), Postives = 74/154 (48.05%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKT----HYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHI-CINKYSSFTCDCPPDMELSEDNRNC 597
            +CI  LW CD ++DC D SDE  C    C ++ F C +S  C+P    CDG  DC +  DE    +   C+ +T      +CG  +  +CI +   C+   +C + +D  ENC    C  +E TCS   CI+K  SF C+   D     D   C
Sbjct:   62 RCIPLLWKCDGDEDCSDGSDESACVKKTCAESDFVC-NSGQCVPNRWQCDGDPDCEDGSDE----SAELCHMRTCRVNEISCG-PQSTQCIPVSWKCDGEKDCDSGEDE-ENCGNVTCSAAEFTCSSGQCISK--SFVCNGQDDCSDGSDELEC 206

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. TrEMBL
Match: A0A1S6KMJ9 (Uncharacterized protein OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 261.536 bits (667), Expect = 1.397e-73
Identity = 165/520 (31.73%), Postives = 283/520 (54.42%), Query Frame = 1

Query:  154 CISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCT--NINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKD-----SLENCKADFCKTSEN-TCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQK---CVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKRVKPINLRIISKESNRQLIKKINEHKIGKYC--SGVINTCRGSCLP 1674
            CISK W CD NQDC+   DE NCPP +C +N+F C     CIP+  LCDG   C++  DE NCT   I SC+  + ++C    ++ CI I ++C+   NC  N+D     S++NC+ + CK   N  CSH C N ++   C CP   +L  DNR C  I++C  +P  C+Q C++   SY C CYDGY ++      C+  T+E + ++L +       +   N   H+  K ++   + + ++DV+L+++    +  +   +  L  SK+     N++ Y     N +N+  +         + D  R LLF+T   +  IYV N TS     ++++    P +I +DP+   ++WIDLG + + P+I+M  M+   +  L+ K +++P  L ID++E++LYW+D  P +I +I++++ +  N KT  +++ +  +PFSI +F N I+W+D ++++I S  KIT     V+ K VKP+ ++++    N+ +  KI+E  +  +      ++ C   CLP
Sbjct:   38 CISKDWWCDGNQDCESGKDESNCPPKVCLENEFLCHSGTQCIPKLLLCDGTFHCVDKSDERNCTKHEIKSCDSISQFDCNKDGEI-CIPISEVCDKKNNCGRNQDEEPGNSVDNCQRNDCKLIPNGGCSHFCTNFFTYIKCHCPLGYKLQPDNRTCVDIDECSASPSKCNQICKNTPGSYECSCYDGYRQNQHNSEYCI--TKEGDRSILITLNGGRQLMIDLNTGSHF-YKPLYNSHESLVNIDVDLHQSPQTMF-WIQQSNGKLGQSKIDLKVNNIEKY--RFLNHKNLSDDHIGQLCTDMSFDWLRGLLFWTSSIEKIIYVTNTTSNVTSVLLNQGLENPRSIAVDPINTGVYWIDLGTKKSSPRIEMMLMNTDNRRVLVSKNLRQPLDLLIDLQERKLYWSDIDPGSINFINLDTPN--NPKT--IISNKLLYPFSIAVFENNIFWTDWRQNQIISIDKITSDSYTVLAKVVKPLAIQVL----NKVIQPKIHESDVTSHACLKNKMHGCSHICLP 542

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. TrEMBL
Match: A0A3Q3FLF7 (Very low density lipoprotein receptor OS=Kryptolebias marmoratus OX=37003 PE=4 SV=1)

HSP 1 Score: 209.534 bits (532), Expect = 7.937e-54
Identity = 138/483 (28.57%), Postives = 231/483 (47.83%), Query Frame = 1

Query:  106 KCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKA-KEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNL---SAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNI-KTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            KC   +  C      +CI K W CD + DC D SDE NCP   C+++QFKC DS  C+P  + C+GV DC +  DE +C N+  CN    + C   +  ECI++  +CN   +C    D  L+ C  + C  +   CSHIC +    F CDC P ++L  D++ C  IN+C  NP +C Q C +    Y C C++GY        PTT   +               +  L    K   ++   Q ++ +LD +  + + +F++ L  K                    S++ +K++   + K +   S    A+D     L+++D    +I V N     +  +  +    P +I +DP+ G L+W D G      KI+ + M+G  +  L+  +I+ P  + +D+ + RLYW D     +  +D+N  ++  + ++  VLA    HPF++ +F +R++W+D +   IY A+K +G DV  +
Sbjct:  208 KCSPSEMQCASG---ECIHKKWRCDGDPDCKDGSDEANCPFRTCEEDQFKC-DSGGCVPGNRQCNGVRDCADGSDEASCRNVTQCNGPEKFKC---RSGECIEMSKVCNKIRDCPDWSDEPLKECNLNECLLNNGGCSHICKDMAIGFECDCTPGLQLL-DHKTCGDINECM-NPGICSQICINLKGGYKCECHNGYQMD-----PTTSVCKAVGKEPCLIFTNRRDVRRLGLERKEYTQMVEQQRNVVALDADF-KQQTLFWADLGQK-----------------AIFSTVLDKRDAGAHKKVIDVQSPVGVAVDWIYKNLYWSDLGTRTISVANFNGTKQKVLFSRGLKEPASIAVDPLSGFLYWSDWGEP---AKIEKSGMNGVDRQVLVATDIQWPNGITLDLIKGRLYWVDSKLHLLCSVDLNGDNRKKVLQSADVLA----HPFALTVFEDRVFWTDGENQAIYGANKFSGSDVVTL 651

HSP 2 Score: 63.5438 bits (153), Expect = 1.485e-6
Identity = 60/175 (34.29%), Postives = 86/175 (49.14%), Query Frame = 1

Query:   97 CHFK-CLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKD-SLENCK-----ADFCKTSENTC-SHICINKYSSFTCDCPPDMELSEDNRNC 597
            CH + C  ++  CG  +  QCI   W CD  +DCD+  DEV+C  + C  N+F C  S  CI R  +C+G +DC +  DE +C   +SC   + + CGN+    CI    +C+ +++C    D S   C         C  SE  C S  CI+K   + CD  PD +   D  NC
Sbjct:   78 CHMRTCRVNEFSCGPGTT-QCIPFFWKCDGEKDCDNGEDEVDCGNVTCALNEFTCA-SGRCISRNFVCNGEDDCGDGSDELDCA-PSSCG-PSEFQCGNSS---CIPASWVCDDDVDCQDESDESPTRCGRHPTPPAKCSPSEMQCASGECIHK--KWRCDGDPDCKDGSDEANC 243

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. TrEMBL
Match: A0A3Q3ABG3 (Very low density lipoprotein receptor OS=Kryptolebias marmoratus OX=37003 PE=4 SV=1)

HSP 1 Score: 209.92 bits (533), Expect = 8.157e-54
Identity = 138/483 (28.57%), Postives = 231/483 (47.83%), Query Frame = 1

Query:  106 KCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKA-KEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNL---SAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNI-KTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            KC   +  C      +CI K W CD + DC D SDE NCP   C+++QFKC DS  C+P  + C+GV DC +  DE +C N+  CN    + C   +  ECI++  +CN   +C    D  L+ C  + C  +   CSHIC +    F CDC P ++L  D++ C  IN+C  NP +C Q C +    Y C C++GY        PTT   +               +  L    K   ++   Q ++ +LD +  + + +F++ L  K                    S++ +K++   + K +   S    A+D     L+++D    +I V N     +  +  +    P +I +DP+ G L+W D G      KI+ + M+G  +  L+  +I+ P  + +D+ + RLYW D     +  +D+N  ++  + ++  VLA    HPF++ +F +R++W+D +   IY A+K +G DV  +
Sbjct:  233 KCSPSEMQCASG---ECIHKKWRCDGDPDCKDGSDEANCPFRTCEEDQFKC-DSGGCVPGNRQCNGVRDCADGSDEASCRNVTQCNGPEKFKC---RSGECIEMSKVCNKIRDCPDWSDEPLKECNLNECLLNNGGCSHICKDMAIGFECDCTPGLQLL-DHKTCGDINECM-NPGICSQICINLKGGYKCECHNGYQMD-----PTTSVCKAVGKEPCLIFTNRRDVRRLGLERKEYTQMVEQQRNVVALDADF-KQQTLFWADLGQK-----------------AIFSTVLDKRDAGAHKKVIDVQSPVGVAVDWIYKNLYWSDLGTRTISVANFNGTKQKVLFSRGLKEPASIAVDPLSGFLYWSDWGEP---AKIEKSGMNGVDRQVLVATDIQWPNGITLDLIKGRLYWVDSKLHLLCSVDLNGDNRKKVLQSADVLA----HPFALTVFEDRVFWTDGENQAIYGANKFSGSDVVTL 676

HSP 2 Score: 63.929 bits (154), Expect = 1.259e-6
Identity = 60/175 (34.29%), Postives = 86/175 (49.14%), Query Frame = 1

Query:   97 CHFK-CLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKD-SLENCK-----ADFCKTSENTC-SHICINKYSSFTCDCPPDMELSEDNRNC 597
            CH + C  ++  CG  +  QCI   W CD  +DCD+  DEV+C  + C  N+F C  S  CI R  +C+G +DC +  DE +C   +SC   + + CGN+    CI    +C+ +++C    D S   C         C  SE  C S  CI+K   + CD  PD +   D  NC
Sbjct:  103 CHMRTCRVNEFSCGPGTT-QCIPFFWKCDGEKDCDNGEDEVDCGNVTCALNEFTCA-SGRCISRNFVCNGEDDCGDGSDELDCAP-SSCG-PSEFQCGNSS---CIPASWVCDDDVDCQDESDESPTRCGRHPTPPAKCSPSEMQCASGECIHK--KWRCDGDPDCKDGSDEANC 268

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. TrEMBL
Match: A0A4W6E9M0 (Very low density lipoprotein receptor OS=Lates calcarifer OX=8187 PE=4 SV=1)

HSP 1 Score: 208.379 bits (529), Expect = 2.407e-53
Identity = 138/469 (29.42%), Postives = 226/469 (48.19%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKA-KEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFST----ALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYF-HPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            +CI K W CD + DC D SDE NCP   C  +QFKC D + CI   K C+G+ DC +  DE NC N+  CN    + C   +  ECI++  +CN   +C    D  ++ C  + C  +   CSHIC +    F CDC P ++L  D++ C  IN+C  NP +C Q C +    Y C C++GY        PTT   +               I  L    K   +I   Q +  +LD + ++ +M+F++ L  K                 +Y + +  + +I  + K +    T    A+D     L+F+D +  +I V N     +  ++++    P +I +DP+ G L+W D G      KI+ + M+G  +  L+  +I+ P  + +D+ + RLYW D     +  +D+N  ++  +   S    +Y  HPF++ +F +R++W+D +   IY A+K TG DV  +
Sbjct:  222 ECIHKKWRCDGDPDCKDGSDEANCPVRTCGPDQFKCDDGN-CIVGSKQCNGIRDCSDGSDEVNCKNMTQCNGPEKFKC---RSGECIEMSKVCNKARDCPDWSDEPIKECNLNECLLNNGGCSHICKDMVIGFECDCTPGLQLI-DHKTCGDINECL-NPGICSQICINLKGGYKCECHNGYQMD-----PTTGVCKAVGKEPCLIFTNRRDIRRLGLERKEYTQIVEQQRNTVALDADFDQ-QMIFWADLGQK----------------AVYSTVLDKRGDIGAHSKVIDNVQTPVGIAVDWIYKNLYFSDLSTKTISVANFNGTKQKVLLNRGLKEPASIAVDPLSGFLYWSDWGEP---AKIEKSGMNGVNRQVLVATDIQWPNGITLDLIKGRLYWVDSKLHMLCSVDLNGDNRKKVLQSS----DYLAHPFALTVFEDRVFWTDGENKAIYGANKFTGSDVVTL 655

HSP 2 Score: 67.3958 bits (163), Expect = 9.983e-8
Identity = 62/175 (35.43%), Postives = 86/175 (49.14%), Query Frame = 1

Query:   97 CHFK-CLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKD-SLENCK-----ADFCKTSENTC-SHICINKYSSFTCDCPPDMELSEDNRNC 597
            CH + C  ++  CG  S  QCI   W CD  +DCD+  DEVNC  + C  N+F C  S  CI R  +C+G +DC +  DE  C   +SC   + + CGN+    CI    +C+ +++C    D S   C         C +SE  C S  CI+K   + CD  PD +   D  NC
Sbjct:   80 CHMRTCRVNEFSCGAGST-QCIPVFWKCDGEKDCDNGEDEVNCGNITCAPNEFTCA-SGRCISRNFVCNGEDDCGDGSDEVECA-PSSCG-PSEFQCGNSS---CIPASWVCDDDVDCQDQSDESPSRCGRHPTPPAKCSSSEMQCRSGECIHK--KWRCDGDPDCKDGSDEANC 245

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. TrEMBL
Match: A0A556U2W0 (Very low-density lipoprotein receptor OS=Bagarius yarrelli OX=175774 GN=Baya_7983 PE=4 SV=1)

HSP 1 Score: 208.764 bits (530), Expect = 2.930e-53
Identity = 136/482 (28.22%), Postives = 238/482 (49.38%), Query Frame = 1

Query:  106 KCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSA---FSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYF-HPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            KCL  +  CG     +CI   W CD + DC D SDE NCPP  C  +QFKC D   CI   + C+G  DC +  DE NC N+  C+    Y C   +  ECI+I  +CN   +C+   D  ++ C  + C  +   CSH+C N    + CDC P ++L  D++ C  IN+C  NP +C Q C +    Y C C++GY  +    V      E +L++++   I  + +       +  ++     +  +LD + +R + +F++ L  K                 ++ +++  +++   + K +        A+D     ++++D    +I V + +   +  + DKD   P +I +DP+ G L+W D G      KI+ + M+G  +  L+E +I+ P  + +D+ + RLYW D     +  +D+N  ++  +    + + +Y  HPF++ +F +RI+W+D +   IY A+K TG DV ++
Sbjct:  324 KCLASEIQCGSG---ECIHSKWRCDGDADCKDGSDERNCPPRSCHPDQFKCDDGS-CIHGSRQCNGFRDCADGTDEDNCKNLTQCSGPDKYKC---RSGECIEISKVCNKVRDCTDWSDEPIKECDLNECLINNGGCSHLCRNLVIGYECDCTPGLQLI-DHKTCGDINECL-NPGICSQICINLKGGYKCECHEGYQMNSSTGVCKAVGKEPSLIFTNRRDIRKLGLE----RREYTQLVEQLRNTVALDADFSR-QQIFWADLGQK----------------AIFSTALDKREDASRHTKVIDVQMPVGIAVDWIYKNIYWSDLGSKTIGVADFSGTRQKVLFDKDLKEPADIAVDPLSGFLYWSDWGEP---AKIEKSGMNGVDRQVLVETDIQWPNGITLDLIKSRLYWVDSKLHTLCSVDLNGDNRKKV----LQSQDYLAHPFALTVFEDRIFWTDGESEAIYGANKFTGSDVVML 768

HSP 2 Score: 70.8626 bits (172), Expect = 8.492e-9
Identity = 68/212 (32.08%), Postives = 98/212 (46.23%), Query Frame = 1

Query:   97 CHFK-CLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKD-SLENCK-----ADFCKTSENTC-SHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQG-CQDNGKSYNCF--CYDGYTE 699
            CH + C  ++  CG  S   CI   W CD  +DCD+  DE++C  + C   +F C  S  C+ +  +C+G +DC +  DE +C+  +SC +   + C N     CI I  +C+ +I+C    D S  +C      A  C  SE  C S  CI  +S + CD   D +   D RNC     C  +   C  G C    +  N F  C DG  E
Sbjct:  194 CHSRTCRTNEFSCGTGSTL-CIPVSWKCDGERDCDNGEDEMSCGNITCSPLEFTCA-SGRCVSQNFVCNGEDDCGDGTDELDCSP-SSC-DANQFRCANAT---CIPISWVCDRDIDCQDQLDESPLHCGRNATPAAKCLASEIQCGSGECI--HSKWRCDGDADCKDGSDERNCPP-RSCHPDQFKCDDGSCIHGSRQCNGFRDCADGTDE 395

HSP 3 Score: 62.003 bits (149), Expect = 4.523e-6
Identity = 51/162 (31.48%), Postives = 76/162 (46.91%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDE------WNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTC-SHICINKYSSFTCDCPPDMELSEDNRNCKHINKC 615
            +C+S+ +VC+   DC D +DE++C P  CD NQF+C ++  CIP   +CD   DC +  DE       N T    C   +   CG+    ECI  +  C+ + +C    D   NC    C   +  C    CI  + S  C+   D     D  NCK++ +C
Sbjct:  251 RCVSQNFVCNGEDDCGDGTDELDCSPSSCDANQFRCANA-TCIPISWVCDRDIDCQDQLDESPLHCGRNATPAAKC-LASEIQCGSG---ECIHSKWRCDGDADCKDGSDE-RNCPPRSCHPDQFKCDDGSCI--HGSRQCNGFRDCADGTDEDNCKNLTQC 404

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Cavefish
Match: vldlr (very low density lipoprotein receptor [Source:NCBI gene;Acc:103023739])

HSP 1 Score: 197.593 bits (501), Expect = 2.304e-53
Identity = 138/497 (27.77%), Postives = 225/497 (45.27%), Query Frame = 1

Query:  106 KCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGY----------TEHDQKCVPTTEENEIXXXXXXXXXXXX-----XXXXXLNPHYKAKEIF---RGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYF-HPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            KC   +  CG     +CI + W CD + DC D SDE NCP   C  +QFKC D   CI   + C+G+ DC +  DE NC N+  CN    + C   +  ECI +  +CN   +C    D  ++ C  + C  +   CSHIC +    + CDC P ++L  D + C  IN+C  NP +C Q C +    Y C C+ GY              + C+  T   +I  L               +   L+  +  + IF    GQ  IFS    L++ E V Y+ ++                             N++M          A+D     ++++D    +I V N     +  + D++   P +I +DP+ G L+W D G      KI+ + M+G  +  L+E +I+ P  + +D+ + RLYW D     +  +D+N  ++  +    + + +Y  HPF++ +F +R++W+D +   IY A+K TG DV ++
Sbjct:  155 KCSVSEILCGSG---ECIHRKWRCDGDADCKDGSDEKNCPARSCRPDQFKCEDGS-CIHGSRQCNGIRDCTDGTDEVNCKNLTQCNGPDKFKC---RSGECIDMHKVCNKARDCPDWSDEPIKECNLNECLLNNGGCSHICRDMVIGYECDCTPGLQLI-DRKTCGDINECL-NPGICSQICINLKGGYKCECHSGYLMDAATGVCKAVGKEPCLIFTNRRDIRKLGLERREYTQIVEQLRNTVALDADFTQQRIFWADLGQKAIFS--TVLDKREDVGYTKVI----------------------------DNVQM------PVGIAVDWIYKNIYWSDLGSKTIVVANFNGTKQKVLFDRNLKEPASIAVDPLSGFLYWSDWGEP---AKIEKSGMNGVDRQVLVETDIQWPNGITLDLIKSRLYWVDSKLHTLCSVDLNGDNRRKV----LQSQDYLAHPFALTVFEDRVFWTDGESEAIYGANKFTGSDVTML 599

HSP 2 Score: 60.8474 bits (146), Expect = 3.637e-9
Identity = 48/160 (30.00%), Postives = 71/160 (44.38%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSH-ICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNP 627
            +CI  +W CD ++DC D SDE  C   +C +  F C +   CIP+   CDG  DC +  DE      N       + C + +   CI    +CN   +C    D  ++C    C  +E  C +  CI   S + CD  PD +   D    +   +C +NP
Sbjct:    2 RCIPSVWQCDGDEDCSDGSDESTCVRKMCAETDFVCRNGQ-CIPKRWHCDGEPDCEDGSDEGTEQCCNVTCALLEFTCTSGR---CISQNFVCNGEDDCGDGSDE-QDCAPSSCGPNEFQCGNATCIP--SGWVCDDDPDCQDHSD----ESPLRCGRNP 150

HSP 3 Score: 59.6918 bits (143), Expect = 7.868e-9
Identity = 52/162 (32.10%), Postives = 79/162 (48.77%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDE------WNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCS-HICINKYSSFTCDCPPDMELSEDNRNCKHINKC 615
            +CIS+ +VC+   DC D SDE +C P  C  N+F+C ++  CIP   +CD   DC ++ DE       N T    C+  +   CG+    ECI  +  C+ + +C    D  +NC A  C+  +  C    CI  + S  C+   D     D  NCK++ +C
Sbjct:   82 RCISQNFVCNGEDDCGDGSDEQDCAPSSCGPNEFQCGNA-TCIPSGWVCDDDPDCQDHSDESPLRCGRNPTPPAKCS-VSEILCGSG---ECIHRKWRCDGDADCKDGSDE-KNCPARSCRPDQFKCEDGSCI--HGSRQCNGIRDCTDGTDEVNCKNLTQC 235

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Cavefish
Match: vldlr (very low density lipoprotein receptor [Source:NCBI gene;Acc:103023739])

HSP 1 Score: 197.208 bits (500), Expect = 8.762e-53
Identity = 138/497 (27.77%), Postives = 225/497 (45.27%), Query Frame = 1

Query:  106 KCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGY----------TEHDQKCVPTTEENEIXXXXXXXXXXXX-----XXXXXLNPHYKAKEIF---RGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYF-HPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            KC   +  CG     +CI + W CD + DC D SDE NCP   C  +QFKC D   CI   + C+G+ DC +  DE NC N+  CN    + C   +  ECI +  +CN   +C    D  ++ C  + C  +   CSHIC +    + CDC P ++L  D + C  IN+C  NP +C Q C +    Y C C+ GY              + C+  T   +I  L               +   L+  +  + IF    GQ  IFS    L++ E V Y+ ++                             N++M          A+D     ++++D    +I V N     +  + D++   P +I +DP+ G L+W D G      KI+ + M+G  +  L+E +I+ P  + +D+ + RLYW D     +  +D+N  ++  +    + + +Y  HPF++ +F +R++W+D +   IY A+K TG DV ++
Sbjct:  233 KCSVSEILCGSG---ECIHRKWRCDGDADCKDGSDEKNCPARSCRPDQFKCEDGS-CIHGSRQCNGIRDCTDGTDEVNCKNLTQCNGPDKFKC---RSGECIDMHKVCNKARDCPDWSDEPIKECNLNECLLNNGGCSHICRDMVIGYECDCTPGLQLI-DRKTCGDINECL-NPGICSQICINLKGGYKCECHSGYLMDAATGVCKAVGKEPCLIFTNRRDIRKLGLERREYTQIVEQLRNTVALDADFTQQRIFWADLGQKAIFS--TVLDKREDVGYTKVI----------------------------DNVQM------PVGIAVDWIYKNIYWSDLGSKTIVVANFNGTKQKVLFDRNLKEPASIAVDPLSGFLYWSDWGEP---AKIEKSGMNGVDRQVLVETDIQWPNGITLDLIKSRLYWVDSKLHTLCSVDLNGDNRRKV----LQSQDYLAHPFALTVFEDRVFWTDGESEAIYGANKFTGSDVTML 677

HSP 2 Score: 60.4622 bits (145), Expect = 4.985e-9
Identity = 51/171 (29.82%), Postives = 75/171 (43.86%), Query Frame = 1

Query:  100 HFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKT----HYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTC-SHICINKYSSFTCDCPPDMELSEDNRNC 597
              +C      CG     +CI  +W CD ++DC D SDE  C   +C +  F C +   CIP+   CDG  DC +  DE        C  +T     ++CG      CI +   C+   +C   +D + NC    C   E TC S  CI++  +F C+   D     D ++C
Sbjct:   25 QAECETSQFQCGNG---RCIPSVWQCDGDEDCSDGSDESTCVRKMCAETDFVCRNGQ-CIPKRWHCDGEPDCEDGSDE----GTEQCYTRTCRMNEFSCG-VGSTPCIPVFWKCDGESDCDNGEDEM-NCGNVTCALLEFTCTSGRCISQ--NFVCNGEDDCGDGSDEQDC 183

HSP 3 Score: 60.077 bits (144), Expect = 8.049e-9
Identity = 52/162 (32.10%), Postives = 79/162 (48.77%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDE------WNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCS-HICINKYSSFTCDCPPDMELSEDNRNCKHINKC 615
            +CIS+ +VC+   DC D SDE +C P  C  N+F+C ++  CIP   +CD   DC ++ DE       N T    C+  +   CG+    ECI  +  C+ + +C    D  +NC A  C+  +  C    CI  + S  C+   D     D  NCK++ +C
Sbjct:  160 RCISQNFVCNGEDDCGDGSDEQDCAPSSCGPNEFQCGNA-TCIPSGWVCDDDPDCQDHSDESPLRCGRNPTPPAKCS-VSEILCGSG---ECIHRKWRCDGDADCKDGSDE-KNCPARSCRPDQFKCEDGSCI--HGSRQCNGIRDCTDGTDEVNCKNLTQC 313

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Cavefish
Match: vldlr (very low density lipoprotein receptor [Source:NCBI gene;Acc:103023739])

HSP 1 Score: 196.823 bits (499), Expect = 9.727e-53
Identity = 138/497 (27.77%), Postives = 225/497 (45.27%), Query Frame = 1

Query:  106 KCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGY----------TEHDQKCVPTTEENEIXXXXXXXXXXXX-----XXXXXLNPHYKAKEIF---RGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYF-HPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            KC   +  CG     +CI + W CD + DC D SDE NCP   C  +QFKC D   CI   + C+G+ DC +  DE NC N+  CN    + C   +  ECI +  +CN   +C    D  ++ C  + C  +   CSHIC +    + CDC P ++L  D + C  IN+C  NP +C Q C +    Y C C+ GY              + C+  T   +I  L               +   L+  +  + IF    GQ  IFS    L++ E V Y+ ++                             N++M          A+D     ++++D    +I V N     +  + D++   P +I +DP+ G L+W D G      KI+ + M+G  +  L+E +I+ P  + +D+ + RLYW D     +  +D+N  ++  +    + + +Y  HPF++ +F +R++W+D +   IY A+K TG DV ++
Sbjct:  233 KCSVSEILCGSG---ECIHRKWRCDGDADCKDGSDEKNCPARSCRPDQFKCEDGS-CIHGSRQCNGIRDCTDGTDEVNCKNLTQCNGPDKFKC---RSGECIDMHKVCNKARDCPDWSDEPIKECNLNECLLNNGGCSHICRDMVIGYECDCTPGLQLI-DRKTCGDINECL-NPGICSQICINLKGGYKCECHSGYLMDAATGVCKAVGKEPCLIFTNRRDIRKLGLERREYTQIVEQLRNTVALDADFTQQRIFWADLGQKAIFS--TVLDKREDVGYTKVI----------------------------DNVQM------PVGIAVDWIYKNIYWSDLGSKTIVVANFNGTKQKVLFDRNLKEPASIAVDPLSGFLYWSDWGEP---AKIEKSGMNGVDRQVLVETDIQWPNGITLDLIKSRLYWVDSKLHTLCSVDLNGDNRRKV----LQSQDYLAHPFALTVFEDRVFWTDGESEAIYGANKFTGSDVTML 677

HSP 2 Score: 60.077 bits (144), Expect = 6.232e-9
Identity = 51/171 (29.82%), Postives = 75/171 (43.86%), Query Frame = 1

Query:  100 HFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKT----HYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTC-SHICINKYSSFTCDCPPDMELSEDNRNC 597
              +C      CG     +CI  +W CD ++DC D SDE  C   +C +  F C +   CIP+   CDG  DC +  DE        C  +T     ++CG      CI +   C+   +C   +D + NC    C   E TC S  CI++  +F C+   D     D ++C
Sbjct:   25 QAECETSQFQCGNG---RCIPSVWQCDGDEDCSDGSDESTCVRKMCAETDFVCRNGQ-CIPKRWHCDGEPDCEDGSDE----GTEQCYTRTCRMNEFSCG-VGSTPCIPVFWKCDGESDCDNGEDEM-NCGNVTCALLEFTCTSGRCISQ--NFVCNGEDDCGDGSDEQDC 183

HSP 3 Score: 59.3066 bits (142), Expect = 1.247e-8
Identity = 52/162 (32.10%), Postives = 79/162 (48.77%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDE------WNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCS-HICINKYSSFTCDCPPDMELSEDNRNCKHINKC 615
            +CIS+ +VC+   DC D SDE +C P  C  N+F+C ++  CIP   +CD   DC ++ DE       N T    C+  +   CG+    ECI  +  C+ + +C    D  +NC A  C+  +  C    CI  + S  C+   D     D  NCK++ +C
Sbjct:  160 RCISQNFVCNGEDDCGDGSDEQDCAPSSCGPNEFQCGNA-TCIPSGWVCDDDPDCQDHSDESPLRCGRNPTPPAKCS-VSEILCGSG---ECIHRKWRCDGDADCKDGSDE-KNCPARSCRPDQFKCEDGSCI--HGSRQCNGIRDCTDGTDEVNCKNLTQC 313

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Cavefish
Match: vldlr (very low density lipoprotein receptor [Source:NCBI gene;Acc:103023739])

HSP 1 Score: 196.823 bits (499), Expect = 1.053e-52
Identity = 138/497 (27.77%), Postives = 225/497 (45.27%), Query Frame = 1

Query:  106 KCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGY----------TEHDQKCVPTTEENEIXXXXXXXXXXXX-----XXXXXLNPHYKAKEIF---RGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYF-HPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            KC   +  CG     +CI + W CD + DC D SDE NCP   C  +QFKC D   CI   + C+G+ DC +  DE NC N+  CN    + C   +  ECI +  +CN   +C    D  ++ C  + C  +   CSHIC +    + CDC P ++L  D + C  IN+C  NP +C Q C +    Y C C+ GY              + C+  T   +I  L               +   L+  +  + IF    GQ  IFS    L++ E V Y+ ++                             N++M          A+D     ++++D    +I V N     +  + D++   P +I +DP+ G L+W D G      KI+ + M+G  +  L+E +I+ P  + +D+ + RLYW D     +  +D+N  ++  +    + + +Y  HPF++ +F +R++W+D +   IY A+K TG DV ++
Sbjct:  233 KCSVSEILCGSG---ECIHRKWRCDGDADCKDGSDEKNCPARSCRPDQFKCEDGS-CIHGSRQCNGIRDCTDGTDEVNCKNLTQCNGPDKFKC---RSGECIDMHKVCNKARDCPDWSDEPIKECNLNECLLNNGGCSHICRDMVIGYECDCTPGLQLI-DRKTCGDINECL-NPGICSQICINLKGGYKCECHSGYLMDAATGVCKAVGKEPCLIFTNRRDIRKLGLERREYTQIVEQLRNTVALDADFTQQRIFWADLGQKAIFS--TVLDKREDVGYTKVI----------------------------DNVQM------PVGIAVDWIYKNIYWSDLGSKTIVVANFNGTKQKVLFDRNLKEPASIAVDPLSGFLYWSDWGEP---AKIEKSGMNGVDRQVLVETDIQWPNGITLDLIKSRLYWVDSKLHTLCSVDLNGDNRRKV----LQSQDYLAHPFALTVFEDRVFWTDGESEAIYGANKFTGSDVTML 677

HSP 2 Score: 60.4622 bits (145), Expect = 6.184e-9
Identity = 51/171 (29.82%), Postives = 75/171 (43.86%), Query Frame = 1

Query:  100 HFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKT----HYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTC-SHICINKYSSFTCDCPPDMELSEDNRNC 597
              +C      CG     +CI  +W CD ++DC D SDE  C   +C +  F C +   CIP+   CDG  DC +  DE        C  +T     ++CG      CI +   C+   +C   +D + NC    C   E TC S  CI++  +F C+   D     D ++C
Sbjct:   25 QAECETSQFQCGNG---RCIPSVWQCDGDEDCSDGSDESTCVRKMCAETDFVCRNGQ-CIPKRWHCDGEPDCEDGSDE----GTEQCYTRTCRMNEFSCG-VGSTPCIPVFWKCDGESDCDNGEDEM-NCGNVTCALLEFTCTSGRCISQ--NFVCNGEDDCGDGSDEQDC 183

HSP 3 Score: 59.6918 bits (143), Expect = 1.033e-8
Identity = 52/162 (32.10%), Postives = 79/162 (48.77%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDE------WNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCS-HICINKYSSFTCDCPPDMELSEDNRNCKHINKC 615
            +CIS+ +VC+   DC D SDE +C P  C  N+F+C ++  CIP   +CD   DC ++ DE       N T    C+  +   CG+    ECI  +  C+ + +C    D  +NC A  C+  +  C    CI  + S  C+   D     D  NCK++ +C
Sbjct:  160 RCISQNFVCNGEDDCGDGSDEQDCAPSSCGPNEFQCGNA-TCIPSGWVCDDDPDCQDHSDESPLRCGRNPTPPAKCS-VSEILCGSG---ECIHRKWRCDGDADCKDGSDE-KNCPARSCRPDQFKCEDGSCI--HGSRQCNGIRDCTDGTDEVNCKNLTQC 313

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Cavefish
Match: ENSAMXT00000019438.2 (low-density lipoprotein receptor-related protein 8 [Source:NCBI gene;Acc:103046677])

HSP 1 Score: 192.971 bits (489), Expect = 4.030e-51
Identity = 138/500 (27.60%), Postives = 235/500 (47.00%), Query Frame = 1

Query:  130 CGKNSF----FQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSL-ENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKRV-KPINLRIISKESNRQLIKKIN 1611
            CG  +F     +CI   W CD + DC D SDE +CP + C  ++F+C D   CI   K C+   DC++  DE  C N   C     + C N    ECI    +C+   +C    D   + C  + C  +   CSHIC+++   + C CP   +L  D R C  I++C +NP+ C Q C +    + C CY GY E D   V  T + E    Y  F++ + +   +L       ++   Q +  ++DV++  N M +      K     + +  +   +V L  S + + + +            ALD  ++ L++TD  D SI V +     +  ++D +   P  I +DP  G +FW D G     PKI+ A M+G  +  L+ + I+ P  + +D+  +RLYW D     I  +D N   +  I + +       HP+++ +F +R+YW+D ++  +YSA++++G DV  + + +  P ++ +  + S  Q     N
Sbjct:  241 CGTGAFRCGSGECIRLAWRCDRDPDCKDKSDEADCPLLTCRPDEFQCGDGS-CIHGIKQCNKAFDCLDRSDEAGCVNATKCEGPLKFLCRNG---ECIDGAKVCDDVKDCKDRSDEPKKECGLNECMLNNGGCSHICVDRPIGYECQCPAGYKLL-DKRTCGDIDEC-ENPDACSQICINLKGDFKCECYQGY-EMDP--VSKTCKAEGKSPYLMFTNRHEIRRIDLV-KRDYTQVVPTQKNAVAMDVDVAANRMFWCDRFHRKIYSAYIHEASDPSRHVTLIDSELHSPEGL------------ALDWVQHNLYWTDSGDRSISVASADGSRRRVLIDTELSEPRAIAVDPEQGFMFWSDWGMR---PKIEKAGMNGVDRQVLVSEGIEWPNGITLDVVGKRLYWVDSKLHLISSVDFNGAQRRVILSSNE---RLGHPYALAVFEDRVYWTDREKEAVYSANRLSGLDVTSLAEHLNDPHDIVVFHELSQPQAPDSCN 712

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Sea Lamprey
Match: lrp2a (low density lipoprotein receptor-related protein 2a [Source:ZFIN;Acc:ZDB-GENE-050119-2])

HSP 1 Score: 168.703 bits (426), Expect = 1.712e-43
Identity = 135/475 (28.42%), Postives = 221/475 (46.53%), Query Frame = 1

Query:  109 CLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDE-VNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNC-TNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYT-EHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGR--LFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITG 1518
            C  D+  C  +    CI   W CD + DCDD SDE   CPP  C     +C D+  C+P    CDG NDC +  DE +C T    C   + + C N +   C+ +  +C+ N +C    D   +C    C  +   CSH C+       C CPP  +L +D +NC  +++C   P  C Q C +   S+ C C  GYT E D++     + +E+ LL  S S IYS +I    P+  +  +  G+  I ++D +     +  Y + V +D +   S L+N            +++Q +   +      + A+D     L++ D+   +I V  L    +  ++  +   P  +V+DP  G   +FW D G     P+I+ A MDG  + T++  ++  P  LAID     LY+ D +   I + D N  ++  +   S L ++  HP +I IF + +YW+D   +++  A+K  G
Sbjct: 1192 CHNDEFQCQSDGL--CIPAGWECDGHPDCDDGSDEHPGCPPRTCAAGYLRC-DNGNCVPESWRCDGDNDCRDGTDERDCPTPPYRCQSPSQWLCPNHRA--CVDLRKVCDGNFDCPDGGDESPHCNEHDCSVNNGGCSHGCVQGPFGAQCTCPPGFQLLDDTKNCADVDEC-DPPGSCSQQCVNEHGSFRCHCDLGYTMESDRRTCKANDRHEVLLLVPSRSQIYSDNITA-TPNVLSSVVRNGR-SIVAVDFDARAGRI--YWADVAEDKIW--SALRNG-----------TDRQLVHKQVGLTVTENLAVDWIGKNLYWLDFVLETIEVSRLDGSHRTVLISTNVTNPRGLVLDPRDGSRTMFWTDWGKN---PRIERAGMDGRLRRTIVSSKLYWPNGLAIDYATNLLYFADAYLDFIDFCDFNGQNRRQVLA-SDLILQ--HPHAITIFEDFVYWTDRSTNRVMRANKWHG 1637

HSP 2 Score: 131.724 bits (330), Expect = 1.137e-31
Identity = 131/529 (24.76%), Postives = 229/529 (43.29%), Query Frame = 1

Query:  154 CISKLWVCDYNQDCDDNSDEV--NCPPMICDK-NQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTK----KLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHICIN-KYSSFTCDCPPDMELSEDNRN-CKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYT----EHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRN----EMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQN-----IEMNLKNLS-AFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAID-IEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKRVKPINLRIISKESNRQLIKKINEHKIGKYCSGVINTCRGSC 1668
            CI   W CD + DC D SDE   +C    C+   +F+C D++ CI   ++C+ V+DC +  DE      + C E T   C   +       CI +  +CN    C  N D     +      +E  C   C N   + F C C P    + +NRN C  +N+C +    C Q CQ+   +Y CFC DGY      + ++C+       + L        Y ++        K  +    ++DI +LD + + +     MV+Y+ L        + +          YL++ SN        I + L+ +S     A+D     +++TD   S I V  L    + ++++     P  I ++P +G ++W D G     PKI+MA MDG  +  L++  +  P  LA+D     R+YW D   + I+ +  +   +      +V++ +  +PF++ +F + +YW+  +  +++  +K  G  VK            I++  S     +   +H   +Y   V N C+G+C
Sbjct: 3819 CIPPSWKCDGDNDCGDGSDEELHHCLDTPCNPPGRFRC-DNNRCIYSHEICNAVDDCGDGSDE----TPDKCKEPTFAPCTEEEFKCASGRCIPMAAVCNNYNECRDNTDETGCNQGQDRTCAERICEQNCTNLPGNGFICSCRPGFTANAENRNNCDDVNEC-EVFGTCPQDCQNAKGTYECFCVDGYRSAAGSYGKRCIANDNSPVLLLADKVRVRKYDLTSQ------KQADYISNEEDIQALDFDWDHDGTGLSMVYYTVLRSGGKFGSIKR---------AYLAAFSNSSENFATGINLGLRYISQPDGIAVDWVGRHIYWTDAQTSRIEVALLDGRYRKQLINSVLDKPATIALNPKLGMMYWTDWGVV---PKIEMAWMDGQQRQHLVQGLLGWPTGLAVDHTNNGRIYWCDAKENVIESVRPDGGDRR-----TVISGDLGNPFTLDVFESNVYWTTRETGQVWQQNKF-GSGVKS----------HILTVNSWLSQARVFQKH---RYNVNVKNPCKGTC 4304

HSP 3 Score: 115.546 bits (288), Expect = 1.665e-26
Identity = 65/183 (35.52%), Postives = 89/183 (48.63%), Query Frame = 1

Query:  154 CISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWN--CTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFC-KTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGY 693
            C+   + CD   DC D SDE  C    C +NQF C ++  CIPR   CDG NDC +  DE    C   +       + CG     EC+ I  +CN   +C+   D  + C  + C   S N C+H C N  +SF C C     L  + R C+ I++C + P+VC Q C++   SY C C  GY
Sbjct: 2967 CVHSRYRCDRRNDCGDGSDERGCTYPTCRQNQFTC-ENGRCIPRIFACDGDNDCGDGSDEDTHLCHQPSPTCAPGFFRCGAG---ECVAIHLVCNQANDCADGSDE-KGCGINECLYASINQCAHNCTNTLTSFYCSCWAGFRLMANGRACEDIDECNETPQVCSQLCENTAGSYFCKCAPGY 3144

HSP 4 Score: 105.916 bits (263), Expect = 1.370e-23
Identity = 114/502 (22.71%), Postives = 207/502 (41.24%), Query Frame = 1

Query:   97 CHFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTH---YNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSEN----TCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGY-TEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDV----------NLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGR--LFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDK 1542
            C  +C   +  C      +C+ + + CD+  DC D SDE  C    C  NQF C  S  CI +  +CDG +DC +  DE  C +  S   + +   + C  +K   CI    +C+   +C    D   N  A    + EN    +C + C    +   C CPP   +S ++  C   + C K   VC Q C++    + C C  GY  E+ + C                                A  +F    D+   D+          + NR   V          V     +QN  L+V++   ++    ++ +++      + A+D   N L+  + +   I V +L   +++ ++ ++   P  I +DP +G+  +F+ D  + +  P+++ A MDG+ +  L+  ++  P  + +D   QR++W D   +   YI+  +   L  KT         HPF I  F + +Y++D    ++   +   G D++V+ +
Sbjct:  152 CTARCPVGEFQCANE---RCVPQSYRCDHIDDCTDGSDENGCVYGTCQGNQFTCA-SGRCILQSWVCDGDDDCFDGSDERGCVSAASEERECYPEEWPCPGSKA--CIPFRKVCDGRRDCPHGTDE-SNSTAGLACSIENCGALSCEYRCHASPAGGACYCPPSFVVSNNSITCMDFDDC-KMWGVCDQFCENRPAGHMCQCSPGYLLEYGKHCRADVTSG------------------------VASLLFSNGKDLVMSDLQGRTVRVLVPSQNRGVAVGVDYHYILRRVFWTDTMQNKVLSVNMDTLAVETVLSVALDMPE----NLAVDWISNKLYIVESSVDRIDVTDLNGANRLTLIAENLGRPRGIALDPTVGKGSIFFSDWDDASGNPRLERAYMDGTNRLALVRTKLGWPAGITLDFVLQRVFWVD---NRFDYIESVTYDGLIRKTILSGGANVPHPFDITTFEHYVYFTDWTRMEVTRVNVFNGSDLQVVHR 614

HSP 5 Score: 88.9669 bits (219), Expect = 2.709e-18
Identity = 60/188 (31.91%), Postives = 86/188 (45.74%), Query Frame = 1

Query:  112 LQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNC---PPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKT----HYNCGNTK--KLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSH-ICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQG 645
            + ++  CG     QCI   WVCD  QDC DN+DE +    P   C   QF C DS  CIP   +CDG NDC +  DE      ++C  +T     + C +    +  CI+   +C+ + +CS   D  +NC    C   E  C + +C+  +S + CD   D     D R C +   C +N   C  G
Sbjct: 2827 IANEFRCGNG---QCIPLSWVCDSEQDCTDNADEPSSCSDPGRTCPGTQFTC-DSGRCIPGSWICDGDNDCGDGSDE---DGRHACGARTCGPHEFTCADASPPRRRCIQRRFVCDGDADCSDALDEHQNCTRRSCTAGEFACDNGLCV--HSRYRCDRRNDCGDGSDERGCTY-PTCRQNQFTCENG 3004

HSP 6 Score: 77.411 bits (189), Expect = 8.171e-15
Identity = 50/164 (30.49%), Postives = 76/164 (46.34%), Query Frame = 1

Query:  109 CLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSH-ICINKYSSFTCDCPPDMELSEDNRNC 597
            C      CG  +   CI + WVCD   DC D+SDE  C P  C   QF+C   + CI R  +CDG  DC +  DE      ++C+  +H+ C +     C++    C+   +C    D  ++C+   C  +E TC++  C N  ++  CD   +     D  NC
Sbjct:    1 CDSGQFRCGSGA---CIPRSWVCDSINDCSDDSDERGCSPATCTTLQFRCRSDNRCIARAFVCDGEADCADRSDEHQNCPGSTCSS-SHFTCASG---HCVQSAFRCDHFQDCDDRSDE-QSCQYPTC--AEMTCANGACFN--TAQRCDGVVNCRDLSDEANC 152

HSP 7 Score: 72.0182 bits (175), Expect = 3.819e-13
Identity = 64/224 (28.57%), Postives = 90/224 (40.18%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDS----LENCKADFCKTSENTC-SHICINKYSSFTCD--------------------CPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKC-----VPTTEE 732
            +CI   W CD   DC D SDE NC P  C +++F+C +   CIP   +C+  NDC +N DE +C  + +C    ++ CG+     CI     C+ + +C    D            +C  S   C +H+CI    S+ CD                    C P      DN      N+C  + E+C+    D        C DG  E   KC      P TEE
Sbjct: 3696 RCIPLRWRCDRYDDCGDGSDERNCAPRPCSESEFRCTNQR-CIPGRWVCNHENDCGDNSDERDC-ELQTC-LPGYFQCGSG---HCIPERLKCDGSADCQDFSDESLCPTRYPNGTWCPPSSFECDNHVCIP--PSWKCDGDNDCGDGSDEELHHCLDTPCNPPGRFRCDN------NRCIYSHEICN-AVDD--------CGDGSDETPDKCKEPTFAPCTEE 3896

HSP 8 Score: 68.1662 bits (165), Expect = 6.580e-12
Identity = 66/245 (26.94%), Postives = 93/245 (37.96%), Query Frame = 1

Query:  130 CGKNSFF-----QCISKLWVCDYNQDCDDNSDE-------VNCPP---------------------MICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSH--ICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQG---CQDNG----KSYNC----FCYDGYTEHDQKCVPTT 726
            C    FF     +C+ +L++CD   DC D SDE       V C P                       C  +QF C   + CIPR  +CD  NDC +  DE  C    +C+    + C + +   CI    +C+ + +C    D    C  + C + + +CS    CI  Y  + CD   D     D   C       + P +CH     CQ +G      + C     C DG  EH   C P T
Sbjct: 1002 CSSTEFFACANGRCVPRLFLCDGYDDCHDGSDERGCGTGNVTCSPYAFTCTNRRCIPIDWRPTRLATTCRADQFTCASGNRCIPRYWICDTDNDCGDGSDERGCDMSGTCH-PMQFQCPDHR---CIDNAYVCDGDSDCVDGADE-RGCVFN-CTSYQFSCSSGDQCIATY--YRCDGAFDCRDRSDEVGCPT-----RAPGLCHNDEFQCQSDGLCIPAGWECDGHPDCDDGSDEH-PGCPPRT 1232

HSP 9 Score: 65.0846 bits (157), Expect = 5.094e-11
Identity = 54/182 (29.67%), Postives = 87/182 (47.80%), Query Frame = 1

Query: 1015 SAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQ---RLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKRVK 1551
            S  S A D     L++TD  + ++ VM L    +  I+  +   P +IV+ P+ G +F+ D    N   KI  A  DGS    ++   +  P  LAID +     +LYW D F   I++ + N  ++  +   S LA    HPFSI I G   Y+SD + + I    K+ G +  +I + ++
Sbjct:  759 SVESLAYDWVSKNLYWTDTRNRAVTVMRLIDQSRRNIL-SNLQNPRSIVVHPLQGYIFYSDW---NRPAKIVRAWCDGSHATPIVNTSLGWPNGLAIDWQSPWNPKLYWVDAFFDRIEFSNFNGQNRQRLDRISHLA----HPFSISIHGGFAYFSDWRLNSIVRVQKMDGGEAVIIRQGIQ 932

HSP 10 Score: 65.0846 bits (157), Expect = 5.270e-11
Identity = 50/219 (22.83%), Postives = 99/219 (45.21%), Query Frame = 1

Query: 1030 ALDPARNLLFFTDYNDSSIYVMNLTSFDK--IKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKRV--KPINLRIISKESNRQLIKKINEHKIGKYCSGVINTCRGSCLP 1674
            A D     ++++DY + +I  M L   ++  + +V +    P  I++DP  G ++W D    +   KI+ A + G+F+  ++   +  P  L +D  E  LYW D +   I+   +    +  I + +V      +PF++ I    +YW+D     +Y A K  G D  V+ + +  +P+++ I++    ++     N+   G         C   C+P
Sbjct: 2433 AFDWINRRIYYSDYANQTIGSMGLDGGNRTVVALVPR----PRAIMLDPCKGYMYWTDW---SVNAKIERATLGGNFRVPIINSSLVWPNGLTLDYSENMLYWADAYRQKIERSTLTGDRREVIVSMAV------YPFALTIHEQHVYWTDWNTKSVYRATKDDGADQVVMIQNLPYRPMDIHILTASKQQRCSNPCNQFNGG---------CSHICVP 2629

HSP 11 Score: 63.5438 bits (153), Expect = 1.744e-10
Identity = 56/226 (24.78%), Postives = 81/226 (35.84%), Query Frame = 1

Query:  121 DHYCGKNSF----FQCISKLWVCDYNQDCDDNSDE--VNCPPMICDKNQFKCPDSDL--------------------------------------------CIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHI-CINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQG 645
            +H C  N +     +CI   W+CD   DC D SDE    C    C   QF+C +                                               CIP   +C+G++DC +N DE  C  I +C+    Y C N +   CI +   C+   +C    D   NC    C  SE  C++  CI     + C+   D   + D R+C+ +  C      C  G
Sbjct: 3556 NHRCNSNQWQCMNKRCIPAAWLCDGGPDCQDGSDEDSATCAARTCAPGQFRCNNGRCIPRSWVCDVDDDCGDGSDEPHDTCMGPSHRCDSHTEFACRTNYRCIPTWAVCNGMDDCRDNSDEQGCAEI-TCDPLGDYRCDNHR---CIPLRWRCDRYDDCGDGSDE-RNCAPRPCSESEFRCTNQRCIP--GRWVCNHENDCGDNSDERDCE-LQTCLPGYFQCGSG 3773

HSP 12 Score: 61.6178 bits (148), Expect = 6.022e-10
Identity = 36/129 (27.91%), Postives = 66/129 (51.16%), Query Frame = 1

Query: 1144 FPFNIVIDPVMGRLFWIDLGNENNGP-KIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYF-HPFSIFIFGNRIYWSDLKEHKIYSAHKITGKD 1524
            +P  I +DP  GRL+W D G+++  P K+  A+MDGS    L    +    F+ +D+ EQ+LYW       I+  D+  L+++ +       +++  HP+ + +  + +Y++D      Y   +  GKD
Sbjct: 1835 YPVGIALDPSRGRLYWTDHGSDSGVPAKVAAADMDGSNPTVLFSGNMDHVDFITLDMREQKLYWAVAGTGVIERGDVTGLNRITV-------VQHLSHPWGVAVHESHLYYTDYD----YEVVERVGKD 1952

HSP 13 Score: 59.3066 bits (142), Expect = 2.993e-9
Identity = 38/127 (29.92%), Postives = 65/127 (51.18%), Query Frame = 1

Query: 1147 PFNIVIDPVMGR-LFWIDLGNENNGPKIKMANMDG-SFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGK 1521
            P  + + P  GR L+W D GN    P I    MDG + +  ++  +++ P  L ID    R++W+D   + I+Y +++   +      + LA    H F++ +F + I+W+D     I SAHK TG+
Sbjct: 3285 PRGVTLHPRFGRVLYWTDWGNT---PYIARVGMDGKNNKSVVISTKLEWPNGLTIDYTTDRIFWSDAHLNYIEYANLDGSHR-----HTTLAGSLPHVFALTVFEDTIFWTDWNTRSIESAHKYTGE 3403

HSP 14 Score: 59.3066 bits (142), Expect = 3.044e-9
Identity = 53/214 (24.77%), Postives = 85/214 (39.72%), Query Frame = 1

Query:   97 CHFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICD-KNQFKCPDSDLCIPREKLCDGVNDCIEN--EDEWNC--------------TNI---------------------------NSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHICINKYSSFTCD---CPPDMELSEDNRNC 597
            C F   +   +  +N   +C+   + CD+  DC D+SDE  C    CD   +F C +   CI R ++C+GVN+C +N   DE  C              TNI                           ++C     + CGN    +CI +  +C++  +C+ N D   +C +D  +T   T           FTCD   C P   + + + +C
Sbjct: 2697 CAFHTCEPTDFTCRNG--RCVRYGYRCDHTNDCGDSSDEEGCAFRTCDPAAEFACTNGR-CIARSQVCNGVNNCRDNATSDEQRCPERTCQPGLLKCLTTNICVLRHYLSGGAAEWRRNDLRRPPPLPLHTCFIANEFRCGNG---QCIPLSWVCDSEQDCTDNADEPSSC-SDPGRTCPGT----------QFTCDSGRCIPGSWICDGDNDC 2893

HSP 15 Score: 57.7658 bits (138), Expect = 1.032e-8
Identity = 44/153 (28.76%), Postives = 65/153 (42.48%), Query Frame = 1

Query:  109 CLQDD-HYCGKNSFF----QCISKLWVCDYNQDCDDNSDEVN--CPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLEN-CKADFCKTSENTC--SHICINKY 537
            C+ D    CG + F     +CI     CD   +C D SDE+   C    C+   F C +   C+     CD  NDC ++ DE  C    +C+    + C N +   CI    +CN   NC  N  S E  C    C+     C  ++IC+ ++
Sbjct: 2653 CINDSGQQCGTSQFTCLNGRCIPFRNKCDNRDNCRDGSDELERVCAFHTCEPTDFTCRNGR-CVRYGYRCDHTNDCGDSSDEEGCA-FRTCDPAAEFACTNGR---CIARSQVCNGVNNCRDNATSDEQRCPERTCQPGLLKCLTTNICVLRH 2800

HSP 16 Score: 51.9878 bits (123), Expect = 6.297e-7
Identity = 55/236 (23.31%), Postives = 100/236 (42.37%), Query Frame = 1

Query: 1030 ALDPARNLLFFTDY--NDSSIYVMNL-TSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKI----------------TGKDVKVIDKRVKPINLRIISKESNRQLIKKINEHKIGKYCSGVINTCRGSCLPNH 1680
            A+D     L+FT+   +++ + V  L TSF ++ +       P ++ +DP    LFW+D G     PKI+ A +DG+ +  +L+  +  P+ L ID     +YW D     I  +  +  +   ++        Y  P+ + I+G+ + W D    K+  A K                 T +DV + D RV+P    +I+    R     +N     ++C  + +    +C   H
Sbjct: 2112 AVDWVAGNLYFTNVFSSETHLEVQRLDTSFRRV-LFKTSVDRPRHLAVDPRARFLFWVDAGQR---PKIERAFLDGTNRSVVLDVGLLSPRSLTIDRATDWVYWADDGLDRIGRLAPDGSTWQVVRE----GRGYPAPYGLAIYGSNLIWVDRNLRKVLQASKEPQASPPPPEVIRDNLGTLRDVTIFDPRVQPTAPELINFNPCR-----LNNGGCQQFCFALPSVTTATCACAH 2334

HSP 17 Score: 51.2174 bits (121), Expect = 9.700e-7
Identity = 50/197 (25.38%), Postives = 69/197 (35.03%), Query Frame = 1

Query:  193 CDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCS--HICINKYSSFTCDCPPDMELSEDNRNCKHI------------NKCFKNPEVCH------QGCQDNGKSYNCFCYDGYTEHDQKCVPT 723
            C DN  E   P   C   +F    +  C+PR  LCDG +DC +  DE  C   N       + C N +   CI I              D      A  C+  + TC+  + CI +Y  + CD   D     D R C               ++C  N  VC        G  + G  +NC  Y        +C+ T
Sbjct:  990 CADNPLEPPTPQ--CSSTEFFACANGRCVPRLFLCDGYDDCHDGSDERGCGTGNVTCSPYAFTCTNRR---CIPI--------------DWRPTRLATTCRADQFTCASGNRCIPRY--WICDTDNDCGDGSDERGCDMSGTCHPMQFQCPDHRCIDNAYVCDGDSDCVDGADERGCVFNCTSYQFSCSSGDQCIAT 1165

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Sea Lamprey
Match: lrp1ab (low density lipoprotein receptor-related protein 1Ab [Source:ZFIN;Acc:ZDB-GENE-030131-7126])

HSP 1 Score: 159.073 bits (401), Expect = 2.434e-40
Identity = 134/499 (26.85%), Postives = 222/499 (44.49%), Query Frame = 1

Query:  148 FQCISKL-----WVCDYNQDCDDNSDEV-------NCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINS----CNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADF----CKTSENTCS--HICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTE----------HDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIF--SLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLS-AFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIE----YFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDV 1527
            FQC + L     W CD   DC DNSDE         CPP      QF+C ++ +C    + CDGV++C +  DE NC   +     CN  + + CG T++ +CI  + +CN   +C         C  D     C    N C    IC +    + C+C P  +       C+ +N+C +   VC Q C +   SY C C   Y +           +Q  +   + NEI  L  +            NP+   ++ ++G   +   ++D ++  N  +F+++     ++ ++S L+ +P     +    S    +++++  L      A+D   + L++TD     I V  L    +  +V      P  IV+DP+ G+++W D GN     KI+ A+MDG+ ++  +EK+++ P  LAID   QRLYW D   S I  I ++        T  V+A++      HPFSI IF + IY      ++++  HK     V
Sbjct: 3628 FQCNNTLCKPLSWKCDGEDDCGDNSDETPEMCLKFQCPP----GRQFRCRNNRVCFWAGRQCDGVDNCGDGSDEENCEKPSPKPRICN-SSEFKCGGTER-KCISTQLVCNRFDDCGDGGSDEVACGGDQFVNECHRPLNPCGDDAICHDTLRGYYCECKPGFQRKATTSICEDVNECAQF-GVCTQLCNNTKGSYKCNCSKNYIKGLHHSCKAEGSEQMVLYIADNNEIRSLAPN------------NPNMAYEQAYQGDATVRIDAMDAHVKSNR-IFWTNW----HMGRISMLELYPAGEHRHRRQTSGTV-VDLDISGLKMPRGVAVDWVADNLYWTDSGRDVIEVAQLRGHYRKTLVSGMIDEPHAIVLDPIRGQMYWSDWGNN---AKIEQASMDGTRRHNFVEKDLQWPTGLAIDFMNQRLYWADAKLSVIGSIRLDG-------TDRVVAVDSKQGLLHPFSIEIFEDYIYGVTYVNNRVFRIHKFGSGTV 4091

HSP 2 Score: 151.754 bits (382), Expect = 6.223e-38
Identity = 129/502 (25.70%), Postives = 225/502 (44.82%), Query Frame = 1

Query:  109 CLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMI--CDKN-QFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHIC-INKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCVPTTEE-NEIXXXXXXXXXXXXXXXXXLNPHYKAKEIF-RGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAF--STALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKK---PKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYF--HPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKR-VKPINLRII 1572
            C  D+  C  +   QCI   W CD + DC D SDE  C  ++  CD   QF C D+  CI +   CDG NDC +N DE  C  +  C   +H +C N   + C+  + +C+ + +C    D  E    D C+ +   C+H C +       C CP  M+L +D ++C  ++ C ++   C Q C+       C CYDG+       +P  E    ++             I  ++ H     +   G  +  ++D +LN++ +  Y + V +D +                LS      ++E+ +++  A     A+D     +++ + N   I V  L    +  +V      P  I +DP  G LFW D   +++ P+I+  +M G+ ++ ++  E+     P  L +D  E R+ W D    +I Y  +   ++L      VL    F  HPF++ +FG  +YW+D + + +  A+K TG++V V+ +   +P +L + 
Sbjct: 1035 CHGDEFQCKADG--QCIPLRWRCDGDTDCIDTSDEKECDGVVRTCDPTLQFSCRDTGRCISKTWFCDGDNDCEDNSDEEGCETM-LCKPPSH-SCANDSSI-CLSPKKLCDGHSDCPDGSD--EGMLCDQCQVNNGGCTHNCTVAPGEGVVCSCPSGMQLGKDKKSCDFMDYCARHLR-CSQRCEQEKSIVKCGCYDGWM-----LMPDGENCQSLDPFVPFIIFSNRHEIRRIDLHKGDYSVLVPGLRNTIAIDFHLNQSSL--YWTDVVEDKIYHGK------------LSETGGLTSVEVVVQHGLATPEGLAVDWIAGNIYWVESNLDQIEVARLNGTMRSTLVAGGIEHPRAIALDPRYGILFWTDW--DSSFPRIEAISMSGTGRH-VIHHEMGAGGWPNGLTVDYLENRIMWIDARSDSI-YSALYDGTEL----IEVLRGHEFLSHPFAVTLFGGEVYWTDWRTNTLVRANKWTGQNVTVVQRTNTQPFDLHVF 1501

HSP 3 Score: 129.413 bits (324), Expect = 7.746e-31
Identity = 103/454 (22.69%), Postives = 200/454 (44.05%), Query Frame = 1

Query:  232 ICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEW----NCTNINS-CNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSE-NTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFR-GQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKD-VKVIDKRVKPINLRI 1569
            +C  NQF+C +    +     CDG  DC +  DE     +C+  NS CN+ + + C N +   C+    +CN   +C    D   NC  + C     + C+  C +    + C C    +L +D + C   ++C +    C Q C ++  S+ C C DGY    Q+   +T    I+   +         +  +N       + + G ++  +LD   +  + V+++ +  + ++++   +      V L+ +S+SN   +            A+D     L++ D    +I V  L    +  +++     P  + +D   G L+W D G     P I    MDGS +  +++ +I  P  L++D    R+YW D     I++ D++  ++      +V++ +  H F++ +F + +YW+D +   +  AHK TG D   +I    +P++L +
Sbjct: 2826 MCGPNQFRCANGRCLLKSSWECDGDFDCHDRSDEAPINPHCSANNSKCNDSSSFPCANGR---CVNESMLCNNQDDCEDGSDE-RNCNINECADRRISGCTQECTDLKIGYKCKCRAGFQLKDDGKTCVDRDEC-RTTYPCSQTCLNSHGSFKCLCTDGYR---QRVNDSTSCKAISDEEAILIFANRYYLRKVNLDGSNYTLLKQGLNNAVALDFEWSE-QWVYWTDVTTQGSMIRRMHMNGSDTQV-LHRTSLSNPDGL------------AVDWIGGNLYWCDKGRDTIEVSKLNGLYRTVLLNNGLKEPRALAVDVRGGYLYWSDWGEH---PHIGRMGMDGSNRSVVIDTKITWPNGLSLDYVNNRIYWADAREDYIQFADMDGANR-----HTVVSEDIPHIFALSLFEDHVYWTDWETKTVNRAHKSTGADRTTLISTLHRPMDLHV 3249

HSP 4 Score: 118.627 bits (296), Expect = 1.514e-27
Identity = 117/495 (23.64%), Postives = 193/495 (38.99%), Query Frame = 1

Query:  148 FQCISKLWVCDYNQDCDDNSDEVNCPPMICDK--------NQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGY-TEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHK--DNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDL------KEHKIYSAHKITGKDVKVIDKRVKPINLRIISKE 1581
              CIS  W CD  +DC D SDE    P IC K        N + C  ++LCI   KLCDG NDC +  D           E TH                           ++  ENC    C+       H C        C C    E++ D + CK  ++C      C Q C +   SY+C C +GY  + D K      +          ++  +V    LN                ++D + +  EM  + ++     ++ L  ++L          L   S ++ I ++L        A+D      +F D  D  I+V N      + ++D + Y P  I +DP MG+LF+ D G     PK++  +MDG     L++ +I  P  +A+D+  + +YW D +   + YI++      N +T  +      H F + +F N +Y + +      +   +   ++    D +V+ + VK   L I  + 
Sbjct:   16 LTCISLGWRCDGEKDCPDGSDE---SPEICQKPNEMKCQVNHYHCLGTELCIHMSKLCDGNNDCPDGYD-----------EGTHC--------------------------REFAENCTVTLCR-------HKCAVTREGPACYCTVGHEVTPDEKGCKDFDECAVY-GTCSQNCLNTDGSYSCSCVEGYLLQPDSKSCKAKNDPVDRPAALLIANSQNVVATYLNGSIVPGLTPVATRQASAMDFSYSE-EMACWVNVGDSPTESRLHCARLAG--------LKGFSGERVINISLNVHHVEQMAIDWLTGNFYFMDDVDDRIFVCNKQGDTCVTLLDLELYNPKAIALDPTMGKLFFTDYGQI---PKVERCDMDGGNCSKLVDSKIVFPHGIALDLVSRLVYWADAY---LDYIEVVDYEGRNRRTI-IQGPSVEHLFGLSVFENYLYATSIDNSNSPQNTTVIRVNRFNSTDYQVLTRVVKGGALHIYHRR 446

HSP 5 Score: 78.1814 bits (191), Expect = 5.333e-15
Identity = 68/289 (23.53%), Postives = 117/289 (40.48%), Query Frame = 1

Query:  952 VDLYLSSISNKQNIEMNLKNL------SAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKE--HKIYSAHKITGKDVKVIDKRVKPINLRIISKESNRQLIKKINEHKIGKYCSGVINTCRGSCLPNHDMPEMPKCFGIPRIEEKIRSKNQSLWLILIPVVILGFV 1794
            VD+ LSSI   +  +   +++           A+D     +++ D     I V  L    +  ++ +    P  I + P  G LFW + G     P+I+ + +DG+ +  L+   I  P  +++D EE +LYW D     I+ ID+ +     +    VL+      FS+ +FG+ IYWSD       I    K    DV  +   +  + L+ + K  N++  K  N       C+     C   CL       M  C      E+ +  ++   +L+     IL  V
Sbjct: 1909 VDMGLSSIHRAKRDQTWREDIITNGLGRVEGIAVDWIAGNIYWIDQGFDVIEVARLNGSFRYVVISQGLDKPRAIAVHPDKGYLFWTEWGQN---PRIERSRLDGTERTVLVNVSIAWPNGISVDYEEDKLYWCDARTDKIERIDLETGENREV----VLSTSNMDMFSVSVFGDYIYWSDRTHANGSIKRGSKENATDVVALRTGIG-VQLKDV-KVFNKERQKGTN------VCARQNGGCEQLCLYRGKARRMCACAHGLLAEDGVSCRDYDGYLLYSERTILKSV 2182

HSP 6 Score: 72.0182 bits (175), Expect = 3.948e-13
Identity = 49/221 (22.17%), Postives = 104/221 (47.06%), Query Frame = 1

Query:  949 NVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNL-----TSFDKIKIVDKDCY-FPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKRV--KPINLRIISKESN 1587
            N+    +  + ++ I  N+ ++     A     + L++T Y  S+I    +      +FD+  +V       P   V+D  +  +FW +  NE + P I  + + G+    ++   I+ P  LAID   ++LY++D     I+  + +   +  +    +L  E  H F + ++G+ ++W+D     +  A+K TG DVKV+   +  +P+ +  ++ ++N
Sbjct: 2240 NIQQLFNDGTGRRVIVENVGSVEGL--AYHRGWDSLYWTSYTTSTITRHTVDQARPGAFDRETVVTMSADDHPRAFVMDECLNLMFWTNW-NELS-PSIMRSFLSGANVQVIVGSNIRTPNGLAIDHRAEKLYFSDATLDKIERCEYDGSHRYVV----ILRSEPVHSFGLAVYGDFVFWTDWVRRAVLRANKFTGTDVKVLRGEIPQQPMGMIALANDTN 2452

HSP 7 Score: 71.633 bits (174), Expect = 5.361e-13
Identity = 48/206 (23.30%), Postives = 94/206 (45.63%), Query Frame = 1

Query:  991 IEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIK--IVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPK---IKMANMDGSFQYTLLE-KEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKRVKPINLRIISKESNR 1590
            ++ N+ N+     A+D     L++TD    +I V  L    + +  +++ +   P  I +DPV G ++W D   +  G K   I+ A MDG+ +   +  K +  P  L++DI    LYW D +   I+ I ++   +  +     L+    HPF +   G+ I+W++ +   +Y    I+     + ++R     +R   +E  +
Sbjct:  575 LKTNINNVEGI--AVDWMGYNLYWTDDGLKTINVARLEKASQARRTLIEGNMTHPRAIAVDPVHGFMYWTDWEEDPKGTKRGKIEHAWMDGTHRSIFVSSKTVLWPNGLSLDIPNGILYWCDAYFDQIERIKLDGTERKVVYDGQELS----HPFGLTHHGHNIFWTEYRLGTVYRYDTISRNTTVLRNERPPIFEIRTYDREQQK 774

HSP 8 Score: 68.9366 bits (167), Expect = 3.916e-12
Identity = 45/137 (32.85%), Postives = 65/137 (47.45%), Query Frame = 1

Query:  103 FKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTC 513
            FKC      C KN    C +  ++CD + DC D SDE NC   +C  +QFKC  +  CIP    C+G ++C + EDE +C  +        + C +TK+  CI    +C+ + +C    D   NC    C   E  C
Sbjct: 3341 FKCRPGQFQC-KNGI--CTNPAFICDGDNDCGDGSDEANCDVHVCLPSQFKCRTTHRCIPGIFRCNGQDNCGDGEDEKDCPEVTC--APNQFQCSSTKR--CIPRVWVCDRDNDCGDGSDEPANCTQMTCGQEEFRC 3470

HSP 9 Score: 62.003 bits (149), Expect = 4.547e-10
Identity = 50/155 (32.26%), Postives = 73/155 (47.10%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVN--CPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFC-KTSENTCSHI-CINKYSSFTCDCPPDMELSEDNRNCKH 603
            +CI + W CD + DC DNSDE    C    C  ++FKC  ++ CIP   LCDG NDC  +EDE N T          ++C +     CI +   C+ + +C    D   +C    C   ++  C++  CIN   ++ CD   D   + D   C H
Sbjct:  838 RCIQERWRCDGDNDCLDNSDEAPEICHQHTCPSDRFKC-QNNRCIPLRWLCDGDNDCGNSEDESNTTCAARTCPPNQFSCASG---HCIPMSWKCDLDDDCGDRSDEPPSCAYPTCFPLTQFACNNGRCINM--NWRCDADNDCADASDEIGCNH 986

HSP 10 Score: 62.003 bits (149), Expect = 4.785e-10
Identity = 39/111 (35.14%), Postives = 56/111 (50.45%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKA 483
            +C+   W CDY+ DC DNSDE  C P  C +++F C +   CI     CDG +DC +  DE +C+    C+    + C N     CI     C+ +I+C    D  +NC A
Sbjct: 3516 RCVPGRWQCDYDNDCGDNSDEEGCTPRPCSESEFSCANG-RCIAGRWRCDGDHDCSDGSDEKDCS--PRCDHD-QFQCRNG---HCIPQRWRCDADIDCIDGSDE-DNCAA 3618

HSP 11 Score: 58.9214 bits (141), Expect = 4.306e-9
Identity = 56/173 (32.37%), Postives = 76/173 (43.93%), Query Frame = 1

Query:  130 CGKNSF----FQCISKL-WVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDS-------DLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHICINKYSSFTCDCPPD-MELSEDNRNCKHIN 609
            CG N F     +C+ K  W CD + DC D SDE    P  C  N  KC DS         C+    LC+  +DC +  DE NC NIN C ++    C  T++   +KI   C          D       D C+T+   CS  C+N + SF C C     +   D+ +CK I+
Sbjct: 2827 CGPNQFRCANGRCLLKSSWECDGDFDCHDRSDEAPINPH-CSANNSKCNDSSSFPCANGRCVNESMLCNNQDDCEDGSDERNC-NINECADRRISGC--TQECTDLKIGYKCKCRAGFQLKDDGKTCVDRDECRTTY-PCSQTCLNSHGSFKCLCTDGYRQRVNDSTSCKAIS 2994

HSP 12 Score: 56.9954 bits (136), Expect = 1.716e-8
Identity = 42/123 (34.15%), Postives = 60/123 (48.78%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDE-VNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCS 516
            +CI   W CD   DC D SDE  +CP   C   QF+C +  +C     +CDG NDC +  DE NC +++ C   + + C  T +  CI     CN   NC   +D  ++C    C  ++  CS
Sbjct: 3314 KCIPFWWKCDTEDDCGDRSDEPADCPDFKCRPGQFQCKNG-ICTNPAFICDGDNDCGDGSDEANC-DVHVC-LPSQFKCRTTHR--CIPGIFRCNGQDNCGDGEDE-KDCPEVTCAPNQFQCS 3430

HSP 13 Score: 49.6766 bits (117), Expect = 3.147e-6
Identity = 48/161 (29.81%), Postives = 71/161 (44.10%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCN------EKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHICINKYS------SFTCDCPPDMELSEDNRNC 597
            +C+  L +C+   DC DNSDE+ C    C  ++F+C D   CI     C+ V DC +  DE  C  +N  +      + + Y   N+  L C+    IC+   +C    D  +NCK    K+    CS    N  S      ++ CD  PD +   D  NC
Sbjct: 2554 RCMETLKLCNGVNDCGDNSDEIACNNSTCGADEFRCGDGS-CIANVTRCNQVVDCDDISDEIGCGPMNCTHYHRLGVQASGYVSCNSTSL-CVLPAWICDGANDCGDYADE-KNCKK---KSGSPGCSPDYFNCPSGPCIPTAWKCDREPDCDDGADELNC 2708

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Sea Lamprey
Match: LRP8 (LDL receptor related protein 8 [Source:HGNC Symbol;Acc:HGNC:6700])

HSP 1 Score: 152.91 bits (385), Expect = 1.187e-39
Identity = 120/470 (25.53%), Postives = 195/470 (41.49%), Query Frame = 1

Query:  235 CDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNIN-SCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYT--EHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQ--NIEMNLKNLSAFST-------------ALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEY-----FHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDV-KVIDKRVKPINLRI 1569
            C  ++ +C D   C+P    CDG  DC +  DE +C N    C     + C   +  EC++   +C+   +C    D  L  C  + C T+   CSH C ++   + C CP   EL  D   C   ++C K P VC Q C +    Y C CY+GYT     Q C  T                          H K   IF  Q D+  +D++    + +   S       + V    N      +Y S +  KQ  +  M+  + S   T             A+D     L++TD    ++ V       +  +  +    P  I +DP+ G ++W D G      KI+ A M+G  +  ++ K+I+ P  + +D+  +RLYW D          + +LS +N+       + +      HPF+I IF +++YW+D ++  IYSA K TG  +  V++    P +L +
Sbjct:    4 CGASELRCTDGS-CVPGSSQCDGFRDCHDGSDEHDCNNTAVDCTGPGWFRC---RSGECLQDRQVCDGKRDCHDWSDEPLSLCNVNECATTNGGCSHTCWDRPLGYECGCPAGYELL-DEYTCGDTDEC-KQPGVCSQLCINYKGGYKCDCYEGYTMDPATQACKATE-------------------------HQKTYLIFANQRDVRRVDLHTRSYKQLI--SRTRNTVAVAVEITAN-----RIYWSDLGQKQVYSAHMDEAHDSTRHTSVLGEAPVFVEGIAIDWVHGNLYWTDSKAKTVAVAKPDGSRRRTLFGQGLSEPRAIAVDPLSGFVYWSDWGQP---AKIEKAGMNGVSRQVIVSKDIEWPNGITLDLVNKRLYWVDS--------KLRTLSSVNLAGGERHEVMHQTDALHHPFAIAIFEDKVYWADGEKEAIYSADKHTGSGISSVVEDLHSPQDLLV 424

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001137.1 (pep scaffold:Pmarinus_7.0:GL476464:95621:179961:-1 gene:ENSPMAG00000001008.1 transcript:ENSPMAT00000001137.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 154.066 bits (388), Expect = 8.434e-39
Identity = 122/461 (26.46%), Postives = 198/461 (42.95%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNC------PPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNC-TNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHIC-INKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGY--TEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSL---VHKDNVLQVSKLQNWPLNVDLYLSSIS----NKQNIEMNLKN--LSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSD 1476
             CI   WVCD + DC D SDE +       P   C +++F+C  +  CIP    CDG  DC++  DE  C     +CN  TH+ C       CI+   +C+ + +C  N D    C    C++ +  CSH C +       C CP  M+L ED + C   + C ++   C Q C+    +  C CYDG+      + C  T + +                            IF  + +I  +D++ +R+  V   SL   +  D     S L  W   VD+    I     N   +E  +    ++    A+D     +++ D+    I V  L    +  +V ++   P  I + P  G LFW + G+    P+I+   +DG+ +  L+   I  P  ++ID +E +LYW D     I+ +D+ + +  ++    VL       FS+ +FG+ IYWSD
Sbjct:  161 HCIPSQWVCDGDNDCGDVSDETHTCEFPARPLRQCREDEFRCAINGNCIPLRWRCDGDADCMDISDEKECDGQRRTCNPGTHFTC--VSNGICIRKAWVCDGDNDCEDNSDEA-GCHVYLCQSDKGGCSHNCTVTPVDGLVCSCPKGMQLGEDRKTCNFTDYCARHLR-CSQRCEQEKGAVKCGCYDGWRLMLDGKSCRSTADADPFVPFI----------------------IFSTRHEIRRIDLH-SRDYSVLVPSLRNAIAIDFHFGQSTLY-WTDVVDVRSRVIRRAFINGTGVETIVTTDVMNTHGLAVDWISGNIYWIDHAFDVIEVARLNGSYRYVVVSEELDKPLAIAVHPQKGYLFWSEWGHS---PRIERTLLDGTERMALVNSSIASPNGISIDYDEGKLYWCDGQTDRIERVDLETGANRHV----VLVATTSDMFSVSVFGSHIYWSD 586

HSP 2 Score: 131.339 bits (329), Expect = 1.341e-31
Identity = 133/537 (24.77%), Postives = 215/537 (40.04%), Query Frame = 1

Query:   97 CHFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMI--CDKNQFKCPDSDLCIPREKLCDGVNDCIENEDE-WNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCK-----ADFCKTSENTCSHI---CI------NKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYT--------EHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRN-----EMVFYSSLVHKDNVLQVSKLQNWPLNVDLY-----LSSISNKQ-----------------NIEMNLKNLSAFS-TALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIE----YFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            C  +C QD   C       CI + W CD + DC D SDE NC   +  C K++F+C +S LC P    CDG +DC +N DE  +      C  +  + C N +   C+ ++ +C+   NC  + D  E+C      A  C   E  C  +   CI      N +         +M    D R    +N+C  N       C D  + Y C C  G+         E   +C+     +++               F    H+  K     +  I+  D N  R          Y+ ++  D+ ++V  +        L+     L SIS+ +                  + + +  L   S  A+D     L++TD     + V  L+  ++  +V      P  I +DPV G+++W D GN     KI+ A+MDG+ +   +E+ ++ P  LA+D   QRLYW D   S I  I ++        T  V+A+       HPF+I +F + IY       +++  HK     V+ +
Sbjct:  949 CSLRCEQDQFQCQNG---HCIPQRWRCDNDADCLDGSDEENCGSAVRLCPKDEFQC-NSTLCKPFSWRCDGEDDCGDNSDEDADHCRAFQCPPRRQFRCRNDRV--CVSLDRVCDGINNCGDHSDE-EHCGEPARGARACTAEEFKCDSLERKCIDVRLLCNHHDDCGDGGSDEMACGGDPR----VNECLSNACGFEASCHDTLQGYYCSCRPGFQWNASISSCEDVDECLHFGTCSQVCNNTKGSHVCSCAENFVKVHHHSCKANDSERTMIYVADNNQVRGLSPQRANARYTQVLLGDDSVRVHSMGVHVRTARLFWTNWHLGSISSMELRPGAGRPRSVRDDTAAVVRLEIPGLRTPSGVAVDWVAGNLYWTDSGRDVVEVAQLSGQNRKTLVSGMIDDPHAIALDPVRGKMYWSDWGNN---AKIEQASMDGTRRRNFVEERVQWPTGLAVDYMNQRLYWADTKLSVISSIRLDG-------TDRVVAVSIKQGLLHPFAIDVFEDHIYGVTYTNSRVFRVHKFGNGTVEFL 1464

HSP 3 Score: 69.707 bits (169), Expect = 1.958e-12
Identity = 62/169 (36.69%), Postives = 83/169 (49.11%), Query Frame = 1

Query:  154 CISKLWVCDYNQDCDDNSDEVN--CPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCT-NINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFC-KTSENTCSHI-CINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQG 645
            CI   W CD + DC D SDE+   C    C  ++FKC + + CIP   LCDG NDC ENEDE N T  + +C  +  + CGN K   CI I   C+ + +CS N D   +C    C   ++ +C++  CIN    + CD   D   S D   C   N C  +   C  G
Sbjct:    1 CIQDQWRCDGDNDCQDGSDELPEICQQHTCISDRFKCKN-NRCIPMRWLCDGDNDCGENEDESNTTCTVRTCPAE-QFTCGNGK---CIPIAWKCDLDNDCSDNSDEPPSCAYPTCLPLTQFSCNNGRCINIR--WRCDSDNDCADSSDEAGCN--NTCADSQFSCKNG 160

HSP 4 Score: 61.2326 bits (147), Expect = 8.108e-10
Identity = 39/111 (35.14%), Postives = 56/111 (50.45%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKA 483
            +CI   W CDY+ DC DNSDE  C P  C +++F C +   CI     CDG +DC++  DE +C+      E+  + C N     CI     C+ + +C    D  ENC +
Sbjct:  887 RCIPGRWHCDYDNDCGDNSDEEGCTPRPCSESEFSCANG-RCIAGRWRCDGDHDCMDGSDEKDCSLR---CEQDQFQCQNG---HCIPQRWRCDNDADCLDGSDE-ENCGS 989

HSP 5 Score: 55.8398 bits (133), Expect = 3.474e-8
Identity = 50/172 (29.07%), Postives = 77/172 (44.77%), Query Frame = 1

Query:  109 CLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVN--CPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHICINKYSSFTCD---CPPDMELSEDNRNCKHIN 609
            C+ D   C  N   +CI   W+CD + DC +N DE N  C    C   QF C +   CIP    CD  NDC +N DE       +C   T ++C N +   CI I   C+++ +C+ + D             E  C++ C +  S F+C    C P   + + + +C  ++
Sbjct:   30 CISDRFKCKNN---RCIPMRWLCDGDNDCGENEDESNTTCTVRTCPAEQFTCGNGK-CIPIAWKCDLDNDCSDNSDEPPSCAYPTCLPLTQFSCNNGR---CINIRWRCDSDNDCADSSD-------------EAGCNNTCAD--SQFSCKNGHCIPSQWVCDGDNDCGDVS 179

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005343.1 (pep scaffold:Pmarinus_7.0:GL479201:37125:45319:-1 gene:ENSPMAG00000004851.1 transcript:ENSPMAT00000005343.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 98.9821 bits (245), Expect = 2.337e-22
Identity = 55/185 (29.73%), Postives = 101/185 (54.59%), Query Frame = 1

Query:  991 IEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFD--KIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNI-KTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            IE  L  +     A+D   N L+   ++DS    +++ + D  + K+ D     P  IV+DP+ G L+W D G      KI+ A M+G+ ++ ++  +I+ P  +A+D+  +RLYW D     +  +D++   ++ +  ++S L     HPFSI +F +++YW+D +E  I+S +K TG   +V+
Sbjct:   17 IEQGLSFVEGL--AVDWIHNTLY---WSDSGFKTLSVATMDGRRRKLFDSGLQEPRAIVVDPIAGWLYWSDWGEP---AKIEKAGMNGANRHAIVTHDIQWPNGIALDLANRRLYWVDSKLHTLSSVDMSGQDRVTVLASYSDL----LHPFSIAVFEDKVYWTDGEEEAIFSMNKFTGSGRRVL 189

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Nematostella
Match: EDO48069 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJZ9])

HSP 1 Score: 181.8 bits (460), Expect = 6.040e-49
Identity = 139/535 (25.98%), Postives = 245/535 (45.79%), Query Frame = 1

Query:  109 CLQDDHYCGKNSF----FQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNC-------TNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELS-EDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYT-EHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMV-------------FYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTL--LEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKRV-KPINLRIISKESNRQLIKKINEHKIG 1626
            C     YC  + +     +CI K WVCD   DC + SDE NC    C  +QF C +   CIP    C+G NDC++N DE +C       T   S  +   + CG++K  +CI    +C+ +++C+ + D  +NC  + CK +   C H C +  + + C C P  +++ +D ++C+ +++C   P  C Q C ++  SY C C +GY  E D+K      +                         K   +F  + DI  L ++ +    V             F + +++  +V++ S +++ PLN    + +I       +N+  L+    A+D     L++TD     I V NL   ++++++      P  IV+ P +G +FW D G E   PKI+   M+G  +  L  +   I  P  L ID    +++W D     I+  +++  ++  I + SV      HPF+I +F + IYW+D  +  IY A+K  GKD  ++   +  P+++ +  ++   +      E+  G
Sbjct:  115 CPNSSQYCKSSEYQCSTGECIHKSWVCDGEFDCLNKSDENNCHSSACHISQFTCANK-RCIPMRDRCNGNNDCLDNSDEADCRMFSLLATKPPSICKDGEFQCGSSK--QCIPESKVCDGSVDCTNSADEPDNCFINECKDNNGPCQHYCNDTKTGYFCSCRPGYKVALDDPKSCRDVDECAI-PGSCSQMCFNSKGSYKCTCMEGYRLEPDKKTCKALGD-------------------------KPFLLFTNRQDIRRLVMDSSDFTQVVPKLRAAIALDYDFATGVIYWSDVIEAS-IKSAPLNNGSAVETI-------VNMSLLTPDGIAVDWVNRKLYWTDTGTDVIEVANLDGRERMRLITTGLQEPRAIVVYPAIGYMFWTDWGEE---PKIERCGMNGDPKTRLQIVNTNILWPNALTIDYTIDKIWWADAKEHTIECANLDGTARRVITSDSV-----HHPFAITVFQDYIYWTDWVKESIYKANKFNGKDRSLVCSGLYSPMDIHVYQQQKQPKFSNPCGENNGG 604

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Nematostella
Match: EDO43938 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXB8])

HSP 1 Score: 178.333 bits (451), Expect = 1.902e-47
Identity = 131/495 (26.46%), Postives = 229/495 (46.26%), Query Frame = 1

Query:  103 FKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNC------TNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYT-EHD-QKC--------VPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKE-IKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
             KC +++  C   +   C+ + W+CD  +DC D SDE  C  + C  ++F C +   CIP  + CDG ++C +  DE  C      T       + H+ CG++    CI    +C+   +C   +D   NC  D CK+    C  +C N  +SF C C    EL +D ++C+ IN+C + P +C Q C +   S+ C C +GY  E D ++C        V  T+ N I                 +    + K+  +G  D  +L  ++ +  M++++           + +Q   +  D  + ++     +E           A+D     +++ D   ++I V  L   + + ++      P  +V+DP  G ++W D G+     KI+ A+MDG+ +  L+  E +++P  LAID   +RLYW D     IK+ ++N       +   V+     +P +I +F + IYW+D +  KIY A+K TGK++ V+
Sbjct:  164 VKCRKNERMCADGN--GCVHRRWICDGERDCLDGSDEAGCGTIGCSSDEFTCTNQK-CIPLPQKCDGTDNCGDGSDEKMCRKYLFSTQPGQVCPRDHFRCGSSTI--CIANSKVCDATPHCPHGEDE-RNCDIDECKSFNGHCLQLCTNTKTSFYCSCFSGYELMDDRKSCRDINEC-EIPGMCSQKCYNTKGSFKCSCMEGYVLEPDGRRCKALGPRPYVLFTDRNSI--------------RLIMTDGKEYKQAVQGLKDARTLGFDV-KESMLYWTDKA-------ATAIQKAKMVPDTTIETVHETGLVE-------PAGLAIDWVGRKMYWADPGANTIEVSELDGSNTMTLISSGLDKPSAVVLDPTEGFIYWTDWGDP---AKIERASMDGTARKVLISGEHLERPAGLAIDYSTRRLYWIDSKLDVIKHCNLN-----GTEVRVVINTGIDNPTAITVFEDHIYWTDSR--KIYKANKFTGKNMTVL 612

HSP 2 Score: 64.3142 bits (155), Expect = 1.069e-10
Identity = 59/208 (28.37%), Postives = 84/208 (40.38%), Query Frame = 1

Query:  130 CGKNSF----FQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTN-INSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVC--HQGCQDNGKSYNCFC----YDGYTEHDQKCVP 720
            C  N F     +CI+  + CD   DC D SDE  C    C   +F C  S  CIP    CD  +DC++  DE NC N   +CN  T + C N +   C+  E +C+   +C  + D  +NC                       T   PP ++  ++ R C   N C     +C   + C D      C       D +T  +QKC+P
Sbjct:   39 CSANEFRCDDGRCITSTFRCDREFDCTDRSDERGCVNKTCAPYEFTCAFSGRCIPGRFRCDHRSDCLDGSDEQNCQNAAKTCNPVTDHTCRNGR---CVLKEWLCDGMDDCGDSSDE-DNC----------------------LTRPTPPPVKCRKNERMCADGNGCVHRRWICDGERDCLDGSDEAGCGTIGCSSDEFTCTNQKCIP 220

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Nematostella
Match: EDO49498 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGB0])

HSP 1 Score: 172.94 bits (437), Expect = 6.788e-46
Identity = 126/477 (26.42%), Postives = 219/477 (45.91%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYT-EHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTL-LEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKRV-KPINLRII 1572
            QCIS  W CD + DC D SDE NC    C   +F C +   CI R+ +CDG NDC +  DE +C  + SC     + C NT +  CI    +C+  ++C    D    C  D C ++   C+ +C++      C C P   L+ DN+ C+ IN+C  N   C Q C +   S++C C  GY  E D++     +  +    +  FS+   +    L P        R   +   +D +  R + +++S +  K  V+  S           Y +    +  I   L  ++A   A+D     L+++D     I V  L    +  ++ +D   P  +V+D   G LFW D G     P+++ + +DGS ++ +    +I  P  L +D+  +R+YW D     I   + +  S+  + + S    +  HPF++ +F + +YW+D +   +    K+ G++V ++   V KP+++  +
Sbjct:  175 QCISLAWRCDGDHDCADKSDERNCTGKTCKPFEFACANGRHCIQRKWICDGENDCGDRSDEVDC-GLESCGND-RWRCSNTSR--CIAKSQVCDGRVDCPDASDEGPGCGLDQCHSNNGGCAQLCMDVPEGVQCSCRPGFTLASDNKTCEDINECL-NSSSCSQRCFNTRGSFSCKCVQGYRLEPDKR---RCKAADSIRPFLYFSTRREIRKLGLPPSQSYTFAVRRLRNTIGIDFDW-REKRLYWSDVYKK--VISRS-----------YFNGTGREDLITDAL--ITAEGVAVDWIGRNLYWSDMRSDRIEVSTLEGKWRRVLLSEDVESPRGLVLDSNAGYLFWTDWGTS---PRVERSWLDGSNRFVISFGIKIVWPNGLTLDLATKRVYWIDAKLDHIVSCEYDGSSKRIVLSGSR---QINHPFAMTLFEDYLYWTDWQNKHVLRVSKLHGENVTLLSAGVSKPMDIHAV 621

HSP 2 Score: 60.077 bits (144), Expect = 1.992e-9
Identity = 51/153 (33.33%), Postives = 75/153 (49.02%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDC--DDNSDEVNCPPMI-CDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHI-CINKYSSFTCDCPPDMELSEDNRNC 597
            +CI   W CD + DC   D SDE NC     C  + F+C +   C PR+ +CDG +DC +  DE  C N +SC     ++C + +   CI +   C+ + +CS   D    C    C  S+ +CS+  CI+   ++ CD   D     D RNC
Sbjct:   55 KCIPLSWRCDGDYDCLAPDLSDEANCSVATNCSASMFRCANGQ-CKPRDWVCDGFDDCGDGSDEKGCAN-HSCT-PAQFSCPSGR---CIPLRWRCDGDGDCSDGADE-RGCPPKNCTDSQFSCSNGQCISL--AWRCDGDHDCADKSDERNC 198

HSP 3 Score: 58.5362 bits (140), Expect = 7.182e-9
Identity = 50/159 (31.45%), Postives = 70/159 (44.03%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDE---VNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENE--DEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTC-SHICINKYSSFTCDCPPDMELSEDNRNCKHIN 609
             CIS  W CD   DC DNSDE     C    C  ++F+C  S  CIP    CDG  DC+  +  DE NC+   +C+  + + C N    +C   + +C+   +C    D  + C    C  ++ +C S  CI     + CD   D     D R C   N
Sbjct:   12 HCISLRWKCDGENDCVDNSDEDEYAGCAEWSCRASEFRCQASRKCIPLSWRCDGDYDCLAPDLSDEANCSVATNCS-ASMFRCANG---QCKPRDWVCDGFDDCGDGSDE-KGCANHSCTPAQFSCPSGRCIPL--RWRCDGDGDCSDGADERGCPPKN 163

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Nematostella
Match: EDO49499 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGB1])

HSP 1 Score: 160.229 bits (404), Expect = 5.151e-41
Identity = 143/539 (26.53%), Postives = 211/539 (39.15%), Query Frame = 1

Query:  103 FKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKL-------------------------------------ECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYT-EHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDI--FSLDV--------NLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKD-VKVIDKRVKPINLRII 1572
            F C  D   C       CI+  WVCD + DC DNSDE+NC  + C   +F C +  +CIP+  +CDG NDC +  DE +  + + C+ K  + C N + +                                      CI +  +C+   +C  N D   +C    CK  +  CS  C+       C C P   +S+D   CK IN+C  +   C   C +   SY C C +GY  E    C P                        + P YK   IF    DI   SLD         NL R   V +  L  K     V +   +  N     SS +    I   L        A+D     L+F + +   IYV  L    +  ++  D   P  I +DP +G LFW D        +I+ ANMDGS +  L +  +     L +D   Q +YW +     I  +  + L +  ++       +  HPF I I+ N +++SD   H I S +K TG    K++     P+ L+I+
Sbjct:  160 FTCAPDKFACASGG---CIASRWVCDGDNDCGDNSDELNCTRLTCPPTKFLCANG-MCIPKSAVCDGENDCGDMSDEPSNCSAHICDPKLEFQCANGRCINKKWRCDGMKDCADGSDESTCGEGTCRPDEWHCIGTSRCIPLSRVCDGTNDCGDNYDEGSHCLDLDCK--KKNCSQRCVQTPRGGECRCFPGYTISKDLITCKDINEC-SSIGRCDHFCYNTPGSYKCACDEGYVLERPHTCKP------------------------VGP-YKPWLIFSNCKDIRQVSLDGTQYDLLIRNLTRAISVDFDWLEKKVYWTDVRENAIYRQNYTWASSSFATTV-IRTGLA--MPVGLAVDWVGRNLYFVESSVRRIYVSKLDGSMRTSLITTDLSKPRGIAVDPRVGYLFWTDW----EAHRIERANMDGSSRVILAKTNVYWANTLTLDYTLQTVYWVEAHLDYIGAMSYDGLKRREVRHNG----DIIHPFGIAIYRNELFFSDWVRHAIISINKFTGNGTTKLVSNLEVPMGLQIL 655

HSP 2 Score: 74.7146 bits (182), Expect = 6.489e-14
Identity = 68/229 (29.69%), Postives = 92/229 (40.17%), Query Frame = 1

Query:   61 LFIFIICLNFYACHFKCLQDDHYCGKNSF-----FQCISKLWVCDYNQDCDDNSDEVNC---------------------------------------PPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSH-ICINKYSSFTCDCPPD-MELSEDNRNC-KHI 606
            L   I+  N Y  H K LQ    CG   F      +CI K W CD   DC D+SDE  C                                        P+ C    F CP+S  CIPR  LCDG+ +C +  DE NC       +K  + C +     CI    +C+ + +C  N D L NC    C  ++  C++ +CI K  S  CD   D  ++S++  NC  HI
Sbjct:   20 LVFLIVAWNHYHVHAKILQQAKNCGSRHFKCVSDGKCIPKSWRCDGEMDCPDSSDEEGCVNRTCSSKEFNCNNQCVPLSWKCDGEKDCRPGGFDEEGCEPVTCASTYFLCPNSSHCIPRRWLCDGLAECEDGSDEKNCQKFTCAPDK--FACASGG---CIASRWVCDGDNDCGDNSDEL-NCTRLTCPPTKFLCANGMCIPK--SAVCDGENDCGDMSDEPSNCSAHI 240

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Nematostella
Match: EDO43726 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXU8])

HSP 1 Score: 139.428 bits (350), Expect = 2.131e-34
Identity = 118/473 (24.95%), Postives = 204/473 (43.13%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYT-EHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDG--SFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLK--EHKIYSAHKITGKDVKVIDKRVKP 1554
            +C+   W CD  +DC D SDE  C    C  ++F C +   CIP  + CDG ++C ++ DE  C     C     + C +T +  CI    +C+   +C   +D    C  D CK     CS  C +    + C C    +L +  R C  I++C +    C Q C++   S+ C C  GY  + D +   T   N         S     ++       +A  I  G+  +  LD +   N ++F++         +  K+    L+    +  I     +  ++         +D +   +++TD   + I V  LT   ++ +       P  IV+DP  G L+W D G      +I+ A MDG  S +  ++  E+  P  L ID   +RLYW D   + +K I+ + L   + +  + +A +  HPF+I +F N +Y++D    E  +   +K TG +  ++ + + P
Sbjct:  218 ECVLGHWRCDGEKDCSDGSDEKGCRKSNCASSEFTCANGQ-CIPSSQRCDGTSNCRDSSDEKACVTPPPC-MPGEFKCQSTGR--CIPESKVCDGTRDCQDGEDEPLRCNIDECKDHNGHCSQKCNDLTLGYNCSCFSGYKL-QGARLCVDIDECAEYG-TCSQVCENRKGSFKCSCLPGYRIDGDGR---TCRANGTLPSLVYSSQFSIRNVTVSGAISQA--IVSGRKGVVGLDYDYKSN-LIFWTD-------AKAEKINRARLDGSGSVEEIVGDVKVPDDV--------TVDWSGRKIYWTDGEQNMIEVAELTGAHRMTLFSSGLDEPRAIVVDPSAGYLYWTDWGYN---ARIERAGMDGDASTRTIIISGELGWPNGLTIDYTIKRLYWAD---ARLKRIESSRLDGSDRRLIADIAPQ--HPFAITVFENYLYYTDWNRDERALRRVNKFTGGERTIVKRVLWP 655

HSP 2 Score: 52.7582 bits (125), Expect = 4.615e-7
Identity = 52/155 (33.55%), Postives = 73/155 (47.10%), Query Frame = 1

Query:  100 HFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIEN--EDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHI-CINKYSSFTCD 555
             F+C+ D          +CI   W CD   DC D SDE    P  C ++QF C +   CI     CDG +DC +    DE NC N+ +C     + C N K   CI     C+   +C  N D   N +   C +++ TCS+  CI+  +S+TCD
Sbjct:    5 QFECVSDQ---------KCIVLRWRCDGEDDCSDGSDEQG-SPKTCLQDQFTCRNGK-CIQATWKCDGEDDCRDGYRSDESNCGNV-TCGAD-EFMCSNRK---CISRSWTCDNQDDCGDNSDEDRNVQR-TCASNQFTCSNGDCIS--NSWTCD 140

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Medaka
Match: vldlr (very low density lipoprotein receptor [Source:NCBI gene;Acc:100125475])

HSP 1 Score: 206.838 bits (525), Expect = 3.537e-56
Identity = 135/465 (29.03%), Postives = 224/465 (48.17%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDS-LENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKA-KEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYF-HPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            +CI K W CD + DC D SDE NCP   C  +QFKC D   CIP  + C+G+ DC +  DE +C N++ C+    + C   +  ECI +  +CN   +C    D  ++ C  + C  +   CSHIC +    F CDC P ++L  D++ C  IN+C  NP +C Q C +    Y C C++GY        PTT   +               +  L    K   +I + Q +  +LD + N+ + +F++ L  K     V   +    +V  + + I N Q         +    A+D      ++TD    +I V N     +  + ++    P +I +DP+ G L+W D G      KI+ + M+G  +  L+E +I+ P  + +D+ + RLYW D     +  +D+N  ++  +    + + EY  HPF++ +F +R++W+D +   IY A+K +G DV  +
Sbjct:  250 ECIHKKWRCDGDPDCKDGSDEANCPVRTCGPDQFKCEDGS-CIPGSRQCNGIRDCTDGSDEVDCKNLSQCSGPEKFKC---RSGECIDMSKVCNKVRDCPDWSDEPIKECNVNECLLNNGGCSHICKDMVIGFECDCTPGLQLI-DHKTCGDINECM-NPGICSQICINLKGGYKCECHNGYQMD-----PTTGVCKAVGKEPCLIFTNRRDVRRLGLERKEYTQIVKQQRNAVALDADFNQ-QTIFWADLGQKAIFSTVLDKRG---DVGTHKTVIENVQ---------TPVGIAVDWIYRNFYWTDLGTKTISVSNFNGTIQKVLFNQGLKEPASIAVDPLSGFLYWSDWGEP---AKIEKSGMNGVDRQVLVETDIQWPNGITLDLIKGRLYWVDSKLHMLCSVDLNGDNRKKV----LQSPEYLAHPFALTVFEDRVFWTDGENQAIYGANKFSGSDVVTL 683

HSP 2 Score: 63.929 bits (154), Expect = 4.254e-10
Identity = 70/216 (32.41%), Postives = 101/216 (46.76%), Query Frame = 1

Query:   97 CHFK-CLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKD-SLENCK-----ADFCKTSENTC-SHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQG-CQDNGKSYNCF--CYDGYTEHDQK 711
            CH + C  ++  CG  +  QCI   W CD  +DCD+  DEVNC  + C  ++F C  S  CI +  +C+  +DC +  DE +C   +SC   + + CGN+    CI    +C+ +++C    D SL  C         C +SE  C S  CI+K   + CD  PD +   D  NC  +  C  +   C  G C    +  N    C DG  E D K
Sbjct:  108 CHMRTCRVNEFSCGAGTT-QCIPVSWKCDGEKDCDNGDDEVNCGNITCSPSEFTCT-SGRCISQNFVCNSEDDCGDGSDEVDCA-PSSCG-PSEFQCGNSS---CIPASWVCDDDVDCQDQSDESLSRCGRHPTPPAKCSSSEMQCLSGECIHK--KWRCDGDPDCKDGSDEANCP-VRTCGPDQFKCEDGSCIPGSRQCNGIRDCTDGSDEVDCK 313

HSP 3 Score: 61.6178 bits (148), Expect = 2.075e-9
Identity = 52/176 (29.55%), Postives = 80/176 (45.45%), Query Frame = 1

Query:   85 NFYACHFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKT----HYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTC-SHICINKYSSFTCDCPPDMELSEDNRNC 597
            + +A   +C  +   CG     +CI  +W CD   DC D SDE +C    C +  F C +   C+P+   CDG  DC +  DE    ++  C+ +T     ++CG     +CI +   C+   +C    D + NC    C  SE TC S  CI++  +F C+   D     D  +C
Sbjct:   25 HVHATKTECETNQFQCGNG---RCIPSIWQCDGEDDCTDGSDEKSCVQKTCAEVDFVCRNGQ-CVPKRWHCDGEPDCEDGSDE----SLEICHMRTCRVNEFSCG-AGTTQCIPVSWKCDGEKDCDNGDDEV-NCGNITCSPSEFTCTSGRCISQ--NFVCNSEDDCGDGSDEVDC 188

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Medaka
Match: ENSORLT00000013030.2 (low-density lipoprotein receptor-related protein 8 [Source:NCBI gene;Acc:101174135])

HSP 1 Score: 192.586 bits (488), Expect = 5.386e-51
Identity = 133/472 (28.18%), Postives = 223/472 (47.25%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSL-ENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKA-KEIFRGQDDIFSLDVNLNRNEMVF--------YSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            +CI   W CD + DC D SDE +CP + C  ++F+C D   CI   K C+ V+DC ++ DE  C N   C     + C N    ECI+   +C++  +C    D   + C  + C  +   CSHIC++    F C CP    L  D + C  I++C +NP+ C Q C +    + C CY+GY E D    P T+  +               I  ++   +   ++   Q +  +LD+++  N + +        YS+ +H+ N       Q  PL VD  L                +    ALD  ++ L++TD  D SI V+++    +  +++ D   P  I +DP  G ++W D G      KI+ A M+G  +  L+ + I+ P  + +D+  +RLYW D     I  +D+N   +   +T    A    HP+S+ +F +RIYW+D     ++ A+++TG+D++ +
Sbjct:  251 ECIRLTWKCDGDPDCKDKSDESDCPLLTCRPDEFQCGDGS-CIHGTKQCNKVHDCPDHSDESGCVNATKCEGPLKFQCKNG---ECIESSRVCDSVKDCKDRSDEPKKECGLNECMINNGGCSHICMDLPIGFECQCPTGYHLL-DKKTCGDIDEC-ENPDACSQICINYKGDFKCECYEGY-EMD----PVTKTCKAEGKSPYLLFTNRHEIRRIDLVKRDYSQVVSAQRNAVALDLDVANNRVFWCDRFHRKIYSAFIHEAN----DPSQQVPL-VDSSLQ---------------TPVGLALDWLQHNLYWTDSGDKSISVVSVDGTKRRVLINSDLSEPRAIAVDPHHGFMYWSDWGTRA---KIEKAGMNGVDRQVLVSENIEWPNGITLDLANRRLYWVDSKLHLIASVDLNGAHR---RTHLSSADTLGHPYSLAVFEDRIYWTDRDRAAVFMANRLTGQDIQAL 685

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Medaka
Match: ENSORLT00000036597.1 (low-density lipoprotein receptor-related protein 1B [Source:NCBI gene;Acc:100049327])

HSP 1 Score: 192.971 bits (489), Expect = 8.227e-51
Identity = 140/494 (28.34%), Postives = 230/494 (46.56%), Query Frame = 1

Query:  124 HYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCP--PMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKC-FKNPEVCHQGCQDNGKSYNCFCYDGY--TEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLT-----SFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKR-VKPINLRII 1572
            H C ++   +C+ + W+CD +QDC D SDE +CP  P  C+  Q++C     CIP    CDG  DC +N DE  C  +        + C +    EC+    +CN   NC+   D   +C+    +  +  CS  C +      C C    +L ED   C  +N+C  + P VC   C +   SY C C+ G+       +C  T E   +  + +        S         AK+       I +LD +  R++  F+        V   SK   W         S  ++++  + +K + A S A+D     L++ D   S I+ + L      S DK  I+D+D   P  + + P  G +FW ++GN     KI+ A MDGS +  ++   +K P  +A+DI  +R+YWT+     +K I   +L   +I+   +  I Y  PFS+ +F + +YWSD K+  + +A K++GK+ +++ KR  +P+ L+II
Sbjct:  348 HRCTQSK--ECLLQEWMCDGDQDCKDGSDEKDCPVAPADCEDFQWQCRSGSACIPTAWRCDGTKDCDDNSDEHECGKLTC--RPHEFQCVSK---ECLDPALVCNGITNCADGSDEGGSCQTKCPEAEQTRCSQGCYSTPEGSRCRCDAGYKLLEDGLTCVDVNECEGRTPAVCSHLCLNTPGSYQCDCHPGFIMEAGGHQCKITGEPFLLVSVQTELYLFGLRSGSLDVLKSPAKQ------GILALDYDW-RDQKAFW--------VSGDSKAIRW---------SSLDQKSTGVLVKGVQANSVAVDWLGRNLYWIDSGKSKIFAIKLAKITMKSMDKTTILDEDLDVPRCLTLLPQKGLMFWTEVGNS---AKIERAGMDGSQRKVVVNSSLKWPGDIAVDIISERIYWTEE---TLKAIGSATLDGDDIRILQMKKITY--PFSVAVFNDMLYWSDAKQRIVQAATKLSGKNRQIVLKRPGQPVALKII 802

HSP 2 Score: 64.3142 bits (155), Expect = 3.604e-10
Identity = 56/190 (29.47%), Postives = 81/190 (42.63%), Query Frame = 1

Query:  172 VCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTC-SHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCVPTTEENE 738
            VCD   DC D SDE +C    CD +QF+C     CI + ++CDGV  C +  DE  C       E   + C  ++   CI    +C+   +C+   D   +C    C +SE  C S  C++  +S  CD  PD     D  +C     C  N   C Q       S  C   +   + DQ C   ++E +
Sbjct:  206 VCDGEPDCRDGSDEEDCLS-TCDSDQFQCAHGKKCIEKSQVCDGVPQCQDRSDELECAKY---MEGCAHQCDKSR---CIPSSFLCDGEQDCADGSDEA-SCAEKECSSSEFKCTSGQCVS--ASMHCDGHPDCWDGSDEESCVKAPVCTTN-HRCTQ-------SKECLLQEWMCDGDQDCKDGSDEKD 377

HSP 3 Score: 56.225 bits (134), Expect = 1.182e-7
Identity = 64/263 (24.33%), Postives = 100/263 (38.02%), Query Frame = 1

Query:   64 FIFII---CLNFYACHFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNT--KKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTC-----------------SHICINK----YSSFTCDCPPDMELSEDNRN-----------CKHINKCFKNPEVCHQ--GCQDNGKSYNCFCYDGYTEHD---QKCVPTT 726
            F+F+    C++  +   +C      C   S  +CI    +CD  QDC D SDE +C    C ++QF+C     CI ++ +CDG   C ++ DE  C        K   NC +    K  C+    +C+   +C    D   +C  D  +  E+                   S +C +K    + +  CD  PD     D  +           C H  KC +  +VC     CQD      C  Y     H     +C+P++
Sbjct:   30 FVFLTVKSCVSAGSSTKRCKVGTVLCKDGS--ECIQYSLLCDGEQDCADGSDEEDCESG-CREDQFQCAHGKKCIDKQHVCDGTAHCQDHSDEQQCM-------KRTDNCAHQCDDKNRCLPATFVCDGERDCLDGTDEA-SCDGDKQEEEEDITVPTAVPSEPLPIRCPLGSKLCRDKSDCVHYNHVCDGEPDCRDGSDEEDCLSTCDSDQFQCAHGKKCIEKSQVCDGVPQCQDRSDELECAKYMEGCAHQCDKSRCIPSS 281

HSP 4 Score: 50.447 bits (119), Expect = 7.651e-6
Identity = 48/168 (28.57%), Postives = 70/168 (41.67%), Query Frame = 1

Query:   97 CHFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSEN-TCSHICINKYSSFTCDCPPDMELSEDNRNC 597
            C   C  D   C      +CI K  VCD    C D SDE+ C   + +    +C D   CIP   LCDG  DC +  DE +C     C+  + + C +    +C+     C+ + +C    D     KA  C T+   T S  C+     + CD   D +   D ++C
Sbjct:  222 CLSTCDSDQFQCAHGK--KCIEKSQVCDGVPQCQDRSDELECAKYM-EGCAHQC-DKSRCIPSSFLCDGEQDCADGSDEASCAE-KECS-SSEFKCTSG---QCVSASMHCDGHPDCWDGSDEESCVKAPVCTTNHRCTQSKECL--LQEWMCDGDQDCKDGSDEKDC 378

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Medaka
Match: ENSORLT00000019609.2 (low-density lipoprotein receptor-related protein 1B [Source:NCBI gene;Acc:100049327])

HSP 1 Score: 192.586 bits (488), Expect = 9.566e-51
Identity = 142/494 (28.74%), Postives = 229/494 (46.36%), Query Frame = 1

Query:  124 HYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCP--PMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKC-FKNPEVCHQGCQDNGKSYNCFCYDGY--TEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLT-----SFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKR-VKPINLRII 1572
            H C ++   +C+ + W+CD +QDC D SDE +CP  P  C+  Q++C     CIP    CDG  DC +N DE  C  +        + C +    EC+    +CN   NC+   D   +C+    +  +  CS  C +      C C    +L ED   C  +N+C  + P VC   C +   SY C C+ G+       +C  T E   +  + +        S         AK+       I +LD +  R++  F+        V   SK   W        SS+  K    + +K + A S A+D     L++ D   S I+ + L      S DK  I+D+D   P  + + P  G +FW ++GN     KI+ A MDGS +  ++   +K P  +A+DI  +R+YWT+     +K I   +L   +I+   +  I Y  PFS+ +F + +YWSD K+  + +A K++GK+ +++ KR  +P+ L+II
Sbjct:  325 HRCTQSK--ECLLQEWMCDGDQDCKDGSDEKDCPVAPADCEDFQWQCRSGSACIPTAWRCDGTKDCDDNSDEHECGKLTC--RPHEFQCVSK---ECLDPALVCNGITNCADGSDEGGSCQTKCPEAEQTRCSQGCYSTPEGSRCRCDAGYKLLEDGLTCVDVNECEGRTPAVCSHLCLNTPGSYQCDCHPGFIMEAGGHQCKITGEPFLLVSVQTELYLFGLRSGSLDVLKSPAKQ------GILALDYDW-RDQKAFW--------VSGDSKAIRW--------SSLDQKSTGVL-VKGVQANSVAVDWLGRNLYWIDSGKSKIFAIKLAKITMKSMDKTTILDEDLDVPRCLTLLPQKGLMFWTEVGNS---AKIERAGMDGSQRKVVVNSSLKWPGDIAVDIISERIYWTEE---TLKAIGSATLDGDDIRILQMKKITY--PFSVAVFNDMLYWSDAKQRIVQAATKLSGKNRQIVLKRPGQPVALKII 779

HSP 2 Score: 64.3142 bits (155), Expect = 4.558e-10
Identity = 56/190 (29.47%), Postives = 81/190 (42.63%), Query Frame = 1

Query:  172 VCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTC-SHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCVPTTEENE 738
            VCD   DC D SDE +C    CD +QF+C     CI + ++CDGV  C +  DE  C       E   + C  ++   CI    +C+   +C+   D   +C    C +SE  C S  C++  +S  CD  PD     D  +C     C  N   C Q       S  C   +   + DQ C   ++E +
Sbjct:  183 VCDGEPDCRDGSDEEDCLS-TCDSDQFQCAHGKKCIEKSQVCDGVPQCQDRSDELECAKY---MEGCAHQCDKSR---CIPSSFLCDGEQDCADGSDEA-SCAEKECSSSEFKCTSGQCVS--ASMHCDGHPDCWDGSDEESCVKAPVCTTN-HRCTQ-------SKECLLQEWMCDGDQDCKDGSDEKD 354

HSP 3 Score: 55.0694 bits (131), Expect = 2.580e-7
Identity = 58/231 (25.11%), Postives = 88/231 (38.10%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNT--KKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTC-----------------SHICINK----YSSFTCDCPPDMELSEDNRN-----------CKHINKCFKNPEVCHQ--GCQDNGKSYNCFCYDGYTEHD---QKCVPTT 726
            +CI    +CD  QDC D SDE +C    C ++QF+C     CI ++ +CDG   C ++ DE  C        K   NC +    K  C+    +C+   +C    D   +C  D  +  E+                   S +C +K    + +  CD  PD     D  +           C H  KC +  +VC     CQD      C  Y     H     +C+P++
Sbjct:   37 ECIQYSLLCDGEQDCADGSDEEDCESG-CREDQFQCAHGKKCIDKQHVCDGTAHCQDHSDEQQCM-------KRTDNCAHQCDDKNRCLPATFVCDGERDCLDGTDEA-SCDGDKQEEEEDITVPTAVPSEPLPIRCPLGSKLCRDKSDCVHYNHVCDGEPDCRDGSDEEDCLSTCDSDQFQCAHGKKCIEKSQVCDGVPQCQDRSDELECAKYMEGCAHQCDKSRCIPSS 258

HSP 4 Score: 50.0618 bits (118), Expect = 9.681e-6
Identity = 48/168 (28.57%), Postives = 70/168 (41.67%), Query Frame = 1

Query:   97 CHFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSEN-TCSHICINKYSSFTCDCPPDMELSEDNRNC 597
            C   C  D   C      +CI K  VCD    C D SDE+ C   + +    +C D   CIP   LCDG  DC +  DE +C     C+  + + C +    +C+     C+ + +C    D     KA  C T+   T S  C+     + CD   D +   D ++C
Sbjct:  199 CLSTCDSDQFQCAHGK--KCIEKSQVCDGVPQCQDRSDELECAKYM-EGCAHQC-DKSRCIPSSFLCDGEQDCADGSDEASCAE-KECS-SSEFKCTSG---QCVSASMHCDGHPDCWDGSDEESCVKAPVCTTNHRCTQSKECL--LQEWMCDGDQDCKDGSDEKDC 355

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Medaka
Match: ldlrb (low-density lipoprotein receptor [Source:NCBI gene;Acc:101161779])

HSP 1 Score: 189.119 bits (479), Expect = 3.997e-50
Identity = 128/463 (27.65%), Postives = 221/463 (47.73%), Query Frame = 1

Query:  151 QCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLE-NCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVI 1536
            QCI   W CD   DCDD SDE+NC   +C + QF+C D   C+     C+ V DC +  DE +C+   +C+  + + C +    ECI +E++C+   +CS   D  E +C  + C T+   CSH C +    F C CP   +L  D RNC+ IN+C +  + C Q C +   SY C C  GY       V  T + E   + +   +        L  H +  ++  G  +  +LD+++ +  + +    + K   L ++   + P+ V    S I   + I            A+D     +++TD    +I V +     +  ++ ++   P  I IDPV   ++W D G+     KI+ + ++G+ +  L+ + I  P  + +D+  QRLYW D     +  ID+N  ++  +    V+     HPFS+ +F ++++W+D     IYSA ++TG+++  I
Sbjct:  207 QCIPGSWRCDGGIDCDDRSDELNCSRPVCLEGQFQCGDGS-CLQGNLKCNSVRDCSDGSDETDCS--TACDAPSEFKCSSG---ECISMENVCDKTKDCSDGSDEPESSCGINECSTANGGCSHHCNDLKIGFNCSCPAGYKLKADQRNCEDINECAE-ADTCSQICINLPGSYKCDCEWGYKIDP---VSNTCKAESGTVPALLFTTRHDVRKILVDHSEYVQVIPGLKNAAALDMDMAQKTLYWSDVSLKKIFRLNLADSSSKPVTV--IDSGIETPEGI------------AVDWVHGNIYWTDSTLKTISVASTDGTKRKTLIRENLDKPRAITIDPVNNFVYWTDWGHH---AKIEKSGLNGAGRVALVTENIVSPNGITLDMVNQRLYWVDSKLHTVFSIDVNGGTRHRV---VVINQRPSHPFSLTVFEDKVFWTDTGLRGIYSASRLTGRNLTQI 639

HSP 2 Score: 75.8702 bits (185), Expect = 8.533e-14
Identity = 52/196 (26.53%), Postives = 100/196 (51.02%), Query Frame = 1

Query: 1000 NLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNL--TSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSA-IKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYS--AHKITGKDVKVIDKRVK-PINLRI 1569
             LKN +A    +D A+  L+++D +   I+ +NL  +S   + ++D     P  I +D V G ++W D    +    I +A+ DG+ + TL+ + + KP+ + ID     +YWTD    A I+   +N   ++ + T ++++    +  ++ +   R+YW D K H ++S   +  T   V VI++R   P +L +
Sbjct:  424 GLKNAAALD--MDMAQKTLYWSDVSLKKIFRLNLADSSSKPVTVIDSGIETPEGIAVDWVHGNIYWTD----STLKTISVASTDGTKRKTLIRENLDKPRAITIDPVNNFVYWTDWGHHAKIEKSGLNGAGRVALVTENIVSP---NGITLDMVNQRLYWVDSKLHTVFSIDVNGGTRHRVVVINQRPSHPFSLTV 610

HSP 3 Score: 65.855 bits (159), Expect = 1.204e-10
Identity = 57/204 (27.94%), Postives = 86/204 (42.16%), Query Frame = 1

Query:   43 LQMRTILFIFIICLNFYACHFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEV--NCPPMICDKNQFKCPDS-DLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHICINKYSSFTCD---CPPDMELSEDNRNCKHINKCFKNPEVC 636
            L   + L + I CL        C      CG     +C+++ W+CD   DC D +DE+   C    C  +QF C    + C+P+   CDG  DC    DE NCT +  C +   + C N    +CI +  +C+ + +CS   D             E TCS    N   SF C+   C P +   + + +C   +   + PE C
Sbjct:    8 LAELSCLLMLIHCLAKTDGALTCSSSQLKCGNG---RCVTRRWICDGTDDCGDGTDELLSTCASKTCLPSQFNCGAPINQCVPKSWHCDGKADCSNGADEKNCT-VKQC-KNDEFRCANG---QCISLSFVCDNDNDCSDGSD-------------ETTCSKPTCNPL-SFQCNNSVCVPSLWRCDGDEDCADGSD--EWPETC 187

HSP 4 Score: 55.0694 bits (131), Expect = 2.273e-7
Identity = 53/171 (30.99%), Postives = 76/171 (44.44%), Query Frame = 1

Query:  109 CLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSL-ENCK----ADFCKTSENTCSHI-CINKYSSFTCDCPPDMELSEDNRNCKH 603
            CL     CG     QC+ K W CD   DC + +DE NC    C  ++F+C +   CI    +CD  NDC +  DE  C+   +CN  + + C N+    C+     C+ + +C+   D   E C     A  C  SE  C++  CI    S+ CD   D +   D  NC  
Sbjct:   71 CLPSQFNCGA-PINQCVPKSWHCDGKADCSNGADEKNCTVKQCKNDEFRCANGQ-CISLSFVCDNDNDCSDGSDETTCSK-PTCNPLS-FQCNNSV---CVPSLWRCDGDEDCADGSDEWPETCGGKKPAAKCSVSEFECANGQCI--PGSWRCDGGIDCDDRSDELNCSR 232

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Planmine SMEST
Match: SMESG000062507.1 (SMESG000062507.1)

HSP 1 Score: 1256.89 bits (3251), Expect = 0.000e+0
Identity = 635/638 (99.53%), Postives = 637/638 (99.84%), Query Frame = 1

Query:   49 MRTILFIFIICLNFYACHFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKRVKPINLRIISKESNRQLIKKINEHKIGKYCSGVINTCRGSCLPNHDMPEMPKCFGIPRIEEKIRSKNQSLWLILIPVVILGFVCIVLFKYRFSRTRITKQPESNRVFVYDSVQFYEDQNSLHDDNTIISDTVPIINNSE 1962
            MRTILFIFIICLNFY CHFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTE+DQKCVPTTEENEINLLYSSFSSIYSVSIFNLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKRVKPINLRIISKESNRQLIKKINEHKIGKYCSGVINTCRGSCLPNHDMPEMPKCFGIPRIEEKIRSKNQSLWLILIPVVILGFVCIVLFKYRFSRTRITKQPESNRVFVYDSVQFYEDQNSLH+DNTIISDTVPIINNSE
Sbjct:    1 MRTILFIFIICLNFYGCHFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTENDQKCVPTTEENEINLLYSSFSSIYSVSIFNLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKRVKPINLRIISKESNRQLIKKINEHKIGKYCSGVINTCRGSCLPNHDMPEMPKCFGIPRIEEKIRSKNQSLWLILIPVVILGFVCIVLFKYRFSRTRITKQPESNRVFVYDSVQFYEDQNSLHNDNTIISDTVPIINNSE 638

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Planmine SMEST
Match: SMESG000034068.1 (SMESG000034068.1)

HSP 1 Score: 259.996 bits (663), Expect = 1.362e-76
Identity = 164/520 (31.54%), Postives = 282/520 (54.23%), Query Frame = 1

Query:  154 CISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCT--NINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKD-----SLENCKADFCKTSEN-TCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQK---CVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKRVKPINLRIISKESNRQLIKKINEHKIGKYC--SGVINTCRGSCLP 1674
            CISK W CD NQDC+   DE NCPP +C +N+F C     CIP+  LCDG   C++  DE NC    I SC+  + ++C    ++ CI I ++C+   NC  N+D     S++NC+ + CK   N  CSH C N ++   C CP   +L  DNR C  I++C  +P  C+Q C++   SY C CYDGY ++      C+  T+E + ++L +       +   N   H+  K ++   + + ++DV+L+++    +  +   +  L  SK+     N++ Y     N +N+  +         + D  R LLF+T   +  IYV N TS     ++++    P +I +DP+   ++WIDLG + + P+I+M  M+   +  L+ K +++P  L ID++E++LYW+D  P +I +I++++ +  N KT  +++ +  +PFSI +F N I+W+D ++++I S  KIT     V+ K VKP+ ++++    N+ +  KI+E  +  +      ++ C   CLP
Sbjct:   38 CISKDWWCDGNQDCESGKDESNCPPKVCLENEFLCHSGTQCIPKLLLCDGTFHCVDKSDERNCMKHEIKSCDSISQFDCNKDGEI-CIPISEVCDKKNNCGRNQDEEPGNSVDNCQRNDCKLIPNGGCSHFCTNFFTYIKCHCPLGYKLQPDNRTCVDIDECSASPSKCNQICKNTPGSYECSCYDGYRQNQHNSEYCI--TKEGDRSILITLNGGRQLMIDLNTGSHF-YKPLYNSHESLVNIDVDLHQSPQTMF-WIQQSNGKLGQSKIDLKVNNIEKY--RFLNHKNLSDDHIGQLCTDMSFDWLRGLLFWTSSIEKIIYVTNTTSNVTSVLLNQGLENPRSIAVDPINTGVYWIDLGTKKSSPRIEMVLMNTDNRRVLVSKNLRQPLDLLIDLQERKLYWSDIDPGSINFINLDTPN--NPKT--IISNKLLYPFSIAVFENNIFWTDWRQNQIISIDKITSDSYTVLAKVVKPLAIQVL----NKVIQPKIHESDVTSHACLKNRMHGCSHICLP 542

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Planmine SMEST
Match: SMESG000034068.1 (SMESG000034068.1)

HSP 1 Score: 259.996 bits (663), Expect = 1.814e-76
Identity = 164/520 (31.54%), Postives = 282/520 (54.23%), Query Frame = 1

Query:  154 CISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCT--NINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKD-----SLENCKADFCKTSEN-TCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQK---CVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKRVKPINLRIISKESNRQLIKKINEHKIGKYC--SGVINTCRGSCLP 1674
            CISK W CD NQDC+   DE NCPP +C +N+F C     CIP+  LCDG   C++  DE NC    I SC+  + ++C    ++ CI I ++C+   NC  N+D     S++NC+ + CK   N  CSH C N ++   C CP   +L  DNR C  I++C  +P  C+Q C++   SY C CYDGY ++      C+  T+E + ++L +       +   N   H+  K ++   + + ++DV+L+++    +  +   +  L  SK+     N++ Y     N +N+  +         + D  R LLF+T   +  IYV N TS     ++++    P +I +DP+   ++WIDLG + + P+I+M  M+   +  L+ K +++P  L ID++E++LYW+D  P +I +I++++ +  N KT  +++ +  +PFSI +F N I+W+D ++++I S  KIT     V+ K VKP+ ++++    N+ +  KI+E  +  +      ++ C   CLP
Sbjct:   38 CISKDWWCDGNQDCESGKDESNCPPKVCLENEFLCHSGTQCIPKLLLCDGTFHCVDKSDERNCMKHEIKSCDSISQFDCNKDGEI-CIPISEVCDKKNNCGRNQDEEPGNSVDNCQRNDCKLIPNGGCSHFCTNFFTYIKCHCPLGYKLQPDNRTCVDIDECSASPSKCNQICKNTPGSYECSCYDGYRQNQHNSEYCI--TKEGDRSILITLNGGRQLMIDLNTGSHF-YKPLYNSHESLVNIDVDLHQSPQTMF-WIQQSNGKLGQSKIDLKVNNIEKY--RFLNHKNLSDDHIGQLCTDMSFDWLRGLLFWTSSIEKIIYVTNTTSNVTSVLLNQGLENPRSIAVDPINTGVYWIDLGTKKSSPRIEMVLMNTDNRRVLVSKNLRQPLDLLIDLQERKLYWSDIDPGSINFINLDTPN--NPKT--IISNKLLYPFSIAVFENNIFWTDWRQNQIISIDKITSDSYTVLAKVVKPLAIQVL----NKVIQPKIHESDVTSHACLKNRMHGCSHICLP 542

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Planmine SMEST
Match: SMESG000034068.1 (SMESG000034068.1)

HSP 1 Score: 259.61 bits (662), Expect = 1.951e-76
Identity = 164/520 (31.54%), Postives = 282/520 (54.23%), Query Frame = 1

Query:  154 CISKLWVCDYNQDCDDNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCT--NINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKD-----SLENCKADFCKTSEN-TCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGCQDNGKSYNCFCYDGYTEHDQK---CVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKRVKPINLRIISKESNRQLIKKINEHKIGKYC--SGVINTCRGSCLP 1674
            CISK W CD NQDC+   DE NCPP +C +N+F C     CIP+  LCDG   C++  DE NC    I SC+  + ++C    ++ CI I ++C+   NC  N+D     S++NC+ + CK   N  CSH C N ++   C CP   +L  DNR C  I++C  +P  C+Q C++   SY C CYDGY ++      C+  T+E + ++L +       +   N   H+  K ++   + + ++DV+L+++    +  +   +  L  SK+     N++ Y     N +N+  +         + D  R LLF+T   +  IYV N TS     ++++    P +I +DP+   ++WIDLG + + P+I+M  M+   +  L+ K +++P  L ID++E++LYW+D  P +I +I++++ +  N KT  +++ +  +PFSI +F N I+W+D ++++I S  KIT     V+ K VKP+ ++++    N+ +  KI+E  +  +      ++ C   CLP
Sbjct:   38 CISKDWWCDGNQDCESGKDESNCPPKVCLENEFLCHSGTQCIPKLLLCDGTFHCVDKSDERNCMKHEIKSCDSISQFDCNKDGEI-CIPISEVCDKKNNCGRNQDEEPGNSVDNCQRNDCKLIPNGGCSHFCTNFFTYIKCHCPLGYKLQPDNRTCVDIDECSASPSKCNQICKNTPGSYECSCYDGYRQNQHNSEYCI--TKEGDRSILITLNGGRQLMIDLNTGSHF-YKPLYNSHESLVNIDVDLHQSPQTMF-WIQQSNGKLGQSKIDLKVNNIEKY--RFLNHKNLSDDHIGQLCTDMSFDWLRGLLFWTSSIEKIIYVTNTTSNVTSVLLNQGLENPRSIAVDPINTGVYWIDLGTKKSSPRIEMVLMNTDNRRVLVSKNLRQPLDLLIDLQERKLYWSDIDPGSINFINLDTPN--NPKT--IISNKLLYPFSIAVFENNIFWTDWRQNQIISIDKITSDSYTVLAKVVKPLAIQVL----NKVIQPKIHESDVTSHACLKNRMHGCSHICLP 542

[Close]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Planmine SMEST
Match: SMESG000013396.1 (SMESG000013396.1)

HSP 1 Score: 157.147 bits (396), Expect = 1.299e-39
Identity = 146/540 (27.04%), Postives = 236/540 (43.70%), Query Frame = 1

Query:  109 CLQDDHYCGKNSFFQCISKLWVCDYNQDCDDN-SDEVNCPPMICDKNQF-KCPDSDLCIPREKLCDGVNDCIENEDEWNCTNIN----SCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSL-----ENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRN-CKHINKCFKNPEVCHQGCQDNGKSYNCFCYDG-YTEHDQKCVPTTEENEIXXXXXXXXXXXXXXXXXLNPHYKAKEIFRGQDDIFSLDVNLN-RNEMVFYSSLVHKDNVLQVSKLQNWPLNVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMNLTSFDKIKIVDKDCYFPF-NIVIDPVMGRLFWIDLGNENNGPKIKMANMDGSFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIKTFS---VLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKRVKPINLRIISKESNRQLIKKINEHKIGKYCSGVINTCRGSCLP 1674
            C  ++ YCG  S   CI+K W CD + DC +   DE+NC    C  ++  +C   D C   ++ CDG  DC +N DE  C+N +    SC+    + C   K   CI  + +C+   +C    D       ENC  + CK +   C   CIN YS   C C P   +   N   C  I++C  +  VC   C +   SY C C++G Y   D K      E  +     +      +    ++  Y  K       +   + ++ + +++ +F++       ++Q+  L +   N+         K    ++ +  S    A D    LLF++D + + I V+N+T+  +  +V    +    +IV+ P   R+FW D G E   PKI+   MDG  +  L++  +  P  LA+D     LYW D             +S  N+KTF    V++    H F I +F + +Y SD    KI   HK TGK  K++    KP+ +++       QL + +N   I   C  + +TC+  CLP
Sbjct:  206 CQNNEFYCGSGSTVPCIAKEWRCDGSYDCPETYRDELNCTNFECSPDKPNRCKTIDSCYDNDQRCDGYPDCTDNSDEKFCSNPSQHDVSCDPFNEFKC--VKNNTCIAFQRVCDKTNDCGDGSDERPGGKSENCDKNLCKINNGNCEQKCINFYSHRKCLCKPGYRIDSINETKCIDIDEC-ADHMVCSHKCANYLGSYKCECFEGFYMSKDNKQCLAVGEKFLLYSTKNSIRELRLLRHYMDMLYSPKN---PTSNFLPIGIDFDYKSKNIFWTQFEPNPEIVQIDHLVSKTGNM---------KPRTLVHSRIHSPVGLAYDWIHGLLFWSDIHFNEISVLNITNGMRKTLVRLGNHSKVRSIVVHPKYRRIFWTDWGKE---PKIECMGMDGQDRKVLIKDGLWTPNGLALDYYFDDLYWVD--------AKTRKISVYNLKTFQRRDVVSHLNAHGFDIDVFEDWLYLSDWDNEKIIQIHKKTGKQ-KILVSSPKPMGVKLF-----HQLAQPVN---IENAC--INHTCQYLCLP 708

HSP 2 Score: 60.077 bits (144), Expect = 5.068e-9
Identity = 69/236 (29.24%), Postives = 101/236 (42.80%), Query Frame = 1

Query:  106 KCLQDDHYCGKNSFFQCISKLWVCDYNQDCDDNSDE-------VNCPPMI-CDKN-QFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTH----------------YNCGNTKKLECIKIEDICNTNINC-STNKDSLENCKADFCKTSENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVC--HQGCQDNGKSYNCFCYDGYTEHDQKCVPTTE 729
            KC  D   C +     CISK  +C++N DC D SDE       +N P ++ CD +  F+C +  LCI R   CDG +DC +  DE NC +  +   K+                 + CG+   + CI  E  C+ + +C  T +D L NC                    ++F  +C PD    + NR CK I+ C+ N + C  +  C DN     C      ++HD  C P  E
Sbjct:   97 KCSIDQFMC-RTKPMNCISKTSLCNHNNDCSDGSDESPEACEIINKPLVVQCDNSIHFQCENKQLCISRIYYCDGKSDCSDQSDEKNCPDSENSKSKSQSLTDLVKQSTICQNNEFYCGSGSTVPCIAKEWRCDGSYDCPETYRDEL-NC--------------------TNF--ECSPD----KPNR-CKTIDSCYDNDQRCDGYPDCTDNSDEKFC---SNPSQHDVSCDPFNE 300

HSP 3 Score: 50.447 bits (119), Expect = 4.656e-6
Identity = 61/194 (31.44%), Postives = 84/194 (43.30%), Query Frame = 1

Query:   64 FIFIICLNFYACHFKCLQDDHYCGKNSFFQ-------CISKLWVCDYNQDCDDNSDEVNCPPMICD-KNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTNINSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKD-SLENCK---ADFCKTSENTCSHICINKY----SSFTCDCPPDMELSEDNRNC 597
            ++ I CL F      C+    Y  +   FQ       CI +   CD + +C DNSDE      ICD +  F C DS++ I + +LCDG  DC  +ED   C   N C+    + C  TK + CI    +CN N +CS   D S E C+          +N+    C NK       + CD   D     D +NC
Sbjct:    3 YLLISCLVF---SIVCVVSSQYYKRCRRFQFLCQNGKCIPETLHCDGHDNCGDNSDE------ICDHRETFTCSDSNI-ILKTELCDGKADCDNDEDPKICVK-NKCS-IDQFMC-RTKPMNCISKTSLCNHNNDCSDGSDESPEACEIINKPLVVQCDNSIHFQCENKQLCISRIYYCDGKSDCSDQSDEKNC 183

The following BLAST results are available for this feature:

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Human
BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Celegans
BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Fly
BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Zebrafish
BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Xenopus
BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Mouse
BLAST of low-density lipoprotein receptor-related protein 2 vs. UniProt/SwissProt
BLAST of low-density lipoprotein receptor-related protein 2 vs. TrEMBL
BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Cavefish
BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Sea Lamprey
BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Yeast
BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Nematostella
BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Medaka
BLAST of low-density lipoprotein receptor-related protein 2 vs. Planmine SMEST

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
VLDLR	2.174e-52	28.86	very low density lipoprotein receptor [Source:HGNC...	[more]
VLDLR	3.026e-52	28.86	very low density lipoprotein receptor [Source:HGNC...	[more]
LDLR	1.233e-50	24.96	low density lipoprotein receptor [Source:HGNC Symb...	[more]
LRP4	2.241e-46	26.86	LDL receptor related protein 4 [Source:HGNC Symbol...	[more]
LDLR	1.253e-45	26.45	low density lipoprotein receptor [Source:HGNC Symb...	[more]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
lrp-1	5.299e-37	26.89	Low-density lipoprotein receptor-related protein ...	[more]
lrp-2	5.218e-36	26.34	Low-density lipoprotein RecePtor related [Source:...	[more]
T13C2.6	6.129e-34	25.14	pep chromosome:WBcel235:II:6783427:6788255:1 gene:...	[more]
T13C2.6	6.164e-34	25.59	pep chromosome:WBcel235:II:6783427:6788255:1 gene:...	[more]
rme-2	1.108e-24	24.75	Receptor Mediated Endocytosis [Source:UniProtKB/T...	[more]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
LpR1	5.317e-51	23.40	gene:FBgn0066101 transcript:FBtr0301466	[more]
LpR1	6.166e-51	23.40	gene:FBgn0066101 transcript:FBtr0335238	[more]
LpR1	9.069e-51	23.69	gene:FBgn0066101 transcript:FBtr0301469	[more]
LpR1	9.510e-51	23.69	gene:FBgn0066101 transcript:FBtr0301467	[more]
LpR1	1.253e-50	23.69	gene:FBgn0066101 transcript:FBtr0301470	[more]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
vldlr	7.846e-53	28.31	very low density lipoprotein receptor [Source:ZFIN...	[more]
vldlr	9.546e-53	28.31	very low density lipoprotein receptor [Source:ZFIN...	[more]
vldlr	1.018e-52	28.31	very low density lipoprotein receptor [Source:ZFIN...	[more]
vldlr	1.050e-52	28.31	very low density lipoprotein receptor [Source:ZFIN...	[more]
vldlr	1.055e-52	28.31	very low density lipoprotein receptor [Source:ZFIN...	[more]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
VLDLR	1.709e-53	27.87	very low density lipoprotein receptor [Source:NCBI...	[more]
VLDLR	2.303e-53	27.66	very low density lipoprotein receptor [Source:NCBI...	[more]
VLDLR	2.511e-53	28.13	very low density lipoprotein receptor [Source:NCBI...	[more]
VLDLR	2.592e-53	27.87	very low density lipoprotein receptor [Source:NCBI...	[more]
VLDLR	2.662e-53	27.87	very low density lipoprotein receptor [Source:NCBI...	[more]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Vldlr	1.492e-51	28.46	very low density lipoprotein receptor [Source:MGI ...	[more]
Vldlr	2.535e-51	28.46	very low density lipoprotein receptor [Source:MGI ...	[more]
Vldlr	2.757e-51	28.46	very low density lipoprotein receptor [Source:MGI ...	[more]
Lrp4	1.005e-46	26.86	low density lipoprotein receptor-related protein 4...	[more]
Ldlr	5.411e-46	26.57	low density lipoprotein receptor [Source:MGI Symbo...	[more]

BLAST of low-density lipoprotein receptor-related protein 2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P98155\|VLDLR_HUMAN	1.044e-51	28.86	Very low-density lipoprotein receptor OS=Homo sapi...	[more]
sp\|P35953\|VLDLR_RABIT	2.332e-51	28.66	Very low-density lipoprotein receptor OS=Oryctolag...	[more]
sp\|P98166\|VLDLR_RAT	1.250e-50	28.66	Very low-density lipoprotein receptor OS=Rattus no...	[more]
sp\|P98156\|VLDLR_MOUSE	1.929e-50	28.46	Very low-density lipoprotein receptor OS=Mus muscu...	[more]
sp\|P98165\|VLDLR_CHICK	3.737e-50	28.43	Very low-density lipoprotein receptor OS=Gallus ga...	[more]

BLAST of low-density lipoprotein receptor-related protein 2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A1S6KMJ9	1.397e-73	31.73	Uncharacterized protein OS=Schmidtea mediterranea ...	[more]
A0A3Q3FLF7	7.937e-54	28.57	Very low density lipoprotein receptor OS=Kryptoleb...	[more]
A0A3Q3ABG3	8.157e-54	28.57	Very low density lipoprotein receptor OS=Kryptoleb...	[more]
A0A4W6E9M0	2.407e-53	29.42	Very low density lipoprotein receptor OS=Lates cal...	[more]
A0A556U2W0	2.930e-53	28.22	Very low-density lipoprotein receptor OS=Bagarius ...	[more]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
vldlr	2.304e-53	27.77	very low density lipoprotein receptor [Source:NCBI...	[more]
vldlr	8.762e-53	27.77	very low density lipoprotein receptor [Source:NCBI...	[more]
vldlr	9.727e-53	27.77	very low density lipoprotein receptor [Source:NCBI...	[more]
vldlr	1.053e-52	27.77	very low density lipoprotein receptor [Source:NCBI...	[more]
ENSAMXT00000019438.2	4.030e-51	27.60	low-density lipoprotein receptor-related protein 8...	[more]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
lrp2a	1.712e-43	28.42	low density lipoprotein receptor-related protein 2...	[more]
lrp1ab	2.434e-40	26.85	low density lipoprotein receptor-related protein 1...	[more]
LRP8	1.187e-39	25.53	LDL receptor related protein 8 [Source:HGNC Symbol...	[more]
ENSPMAT00000001137.1	8.434e-39	26.46	pep scaffold:Pmarinus_7.0:GL476464:95621:179961:-1...	[more]
ENSPMAT00000005343.1	2.337e-22	29.73	pep scaffold:Pmarinus_7.0:GL479201:37125:45319:-1 ...	[more]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO48069	6.040e-49	25.98	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO43938	1.902e-47	26.46	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49498	6.788e-46	26.42	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49499	5.151e-41	26.53	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO43726	2.131e-34	24.95	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
vldlr	3.537e-56	29.03	very low density lipoprotein receptor [Source:NCBI...	[more]
ENSORLT00000013030.2	5.386e-51	28.18	low-density lipoprotein receptor-related protein 8...	[more]
ENSORLT00000036597.1	8.227e-51	28.34	low-density lipoprotein receptor-related protein 1...	[more]
ENSORLT00000019609.2	9.566e-51	28.74	low-density lipoprotein receptor-related protein 1...	[more]
ldlrb	3.997e-50	27.65	low-density lipoprotein receptor [Source:NCBI gene...	[more]

BLAST of low-density lipoprotein receptor-related protein 2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000062507.1	0.000e+0	99.53	SMESG000062507.1	[more]
SMESG000034068.1	1.362e-76	31.54	SMESG000034068.1	[more]
SMESG000034068.1	1.814e-76	31.54	SMESG000034068.1	[more]
SMESG000034068.1	1.951e-76	31.54	SMESG000034068.1	[more]
SMESG000013396.1	1.299e-39	27.04	SMESG000013396.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30020449 ID=SMED30020449|Name=low-density lipoprotein receptor-related protein 2|organism=Schmidtea mediterranea sexual|type=transcript|length=2153bp
TCTGTCGTTACTATATATTCAGTATTAATATATTTATAGTAATTGCAAAT
GAGAACAATATTATTCATTTTTATTATATGTCTAAATTTTTACGCTTGTC
ATTTTAAGTGTTTACAAGATGATCATTATTGTGGAAAAAATAGTTTCTTC
CAATGTATTAGTAAATTATGGGTTTGTGATTACAATCAAGACTGCGATGA
CAATTCTGATGAAGTTAATTGCCCACCGATGATATGTGACAAAAATCAAT
TCAAGTGCCCTGATTCCGATCTCTGTATACCTCGCGAAAAACTATGTGAC
GGTGTAAATGATTGCATCGAGAACGAAGATGAATGGAATTGCACGAACAT
CAATAGTTGTAATGAAAAAACTCATTATAATTGCGGAAATACTAAGAAAT
TAGAATGTATCAAAATTGAAGATATTTGTAATACAAATATTAATTGTTCT
ACAAACAAAGATAGCTTAGAAAATTGCAAGGCTGATTTTTGTAAAACTTC
AGAAAATACTTGCAGTCATATATGTATTAACAAATATTCATCGTTCACAT
GTGACTGTCCTCCTGACATGGAATTGTCTGAAGATAATCGAAATTGTAAA
CATATAAATAAGTGTTTCAAAAATCCCGAGGTTTGCCATCAGGGTTGTCA
AGATAATGGAAAATCATATAATTGTTTTTGTTATGATGGATACACTGAAC
ATGATCAGAAATGTGTCCCAACTACTGAGGAAAATGAAATAAATTTATTG
TATTCTAGCTTCAGTAGTATTTACAGTGTATCTATCTTTAATTTAAATCC
TCATTACAAGGCCAAAGAAATTTTCAGAGGCCAGGATGATATTTTTTCAT
TAGATGTCAATTTAAATAGAAATGAAATGGTGTTTTATTCAAGTCTTGTT
CATAAAGACAATGTATTACAAGTTTCGAAATTACAGAATTGGCCATTAAA
CGTGGATTTATATTTATCGTCAATTTCTAATAAACAGAATATAGAAATGA
ATTTAAAAAATTTATCGGCTTTTAGCACTGCACTAGATCCAGCTAGAAAT
TTGCTCTTTTTTACCGATTATAACGATTCTTCTATTTATGTTATGAATCT
GACTAGTTTTGACAAAATAAAAATTGTCGATAAAGATTGCTATTTCCCAT
TTAATATTGTGATTGATCCTGTAATGGGAAGATTATTTTGGATTGATTTG
GGTAATGAAAACAATGGACCTAAAATTAAAATGGCTAATATGGATGGCAG
TTTTCAATATACACTATTAGAGAAGGAAATTAAAAAACCAAAATTTCTTG
CAATCGATATTGAGGAGCAACGACTTTATTGGACTGATCATTTTCCTTCT
GCAATTAAGTATATTGACATTAATTCCTTAAGCCAGCTCAACATTAAAAC
TTTTTCGGTTTTGGCTATAGAATATTTCCATCCTTTTTCCATATTCATAT
TTGGAAATAGAATATATTGGTCGGATCTTAAAGAACATAAAATCTATTCT
GCACATAAAATTACCGGTAAAGACGTTAAAGTTATAGACAAGAGAGTCAA
ACCAATAAATTTACGAATTATATCTAAAGAGTCAAATCGCCAACTTATTA
AAAAAATTAATGAACATAAAATTGGGAAATATTGTTCTGGTGTCATAAAT
ACTTGCCGCGGTAGTTGTTTACCAAATCATGATATGCCTGAAATGCCAAA
ATGCTTTGGAATTCCAAGAATTGAAGAAAAAATAAGAAGTAAAAATCAAT
CGCTTTGGTTGATTTTGATTCCAGTTGTTATATTGGGTTTCGTATGTATA
GTTTTATTTAAATATCGATTTTCAAGAACTCGAATCACAAAGCAACCTGA
AAGTAACAGAGTTTTTGTCTATGACTCTGTACAGTTCTATGAGGATCAAA
ACAGCCTTCATGATGATAATACAATAATATCAGATACTGTCCCTATAATT
AACAACAGCGAATAGGTTTTCCCAGTAACGGTTTTATTGCTACAAAGATT
TTCGACTTTGGTTAACTTTGTTAGCATGTTTCATTATTGGAAATTAGTGT
TTTTGAGTATACAATATAAATTTCATTTGACAATTTTCATGTATCATCTT
TTGTGTTATTTAATAATGTGTTTGAAATAAAAAATATGTATTTTAAAAAA
AAA

protein sequence of SMED30020449-orf-1

>SMED30020449-orf-1 ID=SMED30020449-orf-1|Name=SMED30020449-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=639bp
MRTILFIFIICLNFYACHFKCLQDDHYCGKNSFFQCISKLWVCDYNQDCD
DNSDEVNCPPMICDKNQFKCPDSDLCIPREKLCDGVNDCIENEDEWNCTN
INSCNEKTHYNCGNTKKLECIKIEDICNTNINCSTNKDSLENCKADFCKT
SENTCSHICINKYSSFTCDCPPDMELSEDNRNCKHINKCFKNPEVCHQGC
QDNGKSYNCFCYDGYTEHDQKCVPTTEENEINLLYSSFSSIYSVSIFNLN
PHYKAKEIFRGQDDIFSLDVNLNRNEMVFYSSLVHKDNVLQVSKLQNWPL
NVDLYLSSISNKQNIEMNLKNLSAFSTALDPARNLLFFTDYNDSSIYVMN
LTSFDKIKIVDKDCYFPFNIVIDPVMGRLFWIDLGNENNGPKIKMANMDG
SFQYTLLEKEIKKPKFLAIDIEEQRLYWTDHFPSAIKYIDINSLSQLNIK
TFSVLAIEYFHPFSIFIFGNRIYWSDLKEHKIYSAHKITGKDVKVIDKRV
KPINLRIISKESNRQLIKKINEHKIGKYCSGVINTCRGSCLPNHDMPEMP
KCFGIPRIEEKIRSKNQSLWLILIPVVILGFVCIVLFKYRFSRTRITKQP
ESNRVFVYDSVQFYEDQNSLHDDNTIISDTVPIINNSE*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000020	protonephridia
PLANA:0000034	epidermis
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036055	LDL_receptor-like_sf
IPR040093	LRAD1
IPR002172	LDrepeatLR_classA_rpt
IPR001881	EGF-like_Ca-bd_dom
IPR000033	LDLR_classB_rpt
IPR000742	EGF-like_dom
IPR011042	6-blade_b-propeller_TolB-like
IPR023415	LDLR_class-A_CS
IPR009030	Growth_fac_rcpt_cys_sf
IPR013809	ENTH

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding
GO:0005509	calcium ion binding

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0016021	integral component of membrane

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR002172	Low-density lipoprotein (LDL) receptor class A repeat	PRINTS	PR00261	LDLRECEPTOR	coord: 34..55 score: 48.34 coord: 118..139 score: 24.17 coord: 74..95 score: 44.79
IPR002172	Low-density lipoprotein (LDL) receptor class A repeat	SMART	SM00192	LDLa_2	coord: 103..145 e-value: 0.27 score: 9.2 coord: 20..60 e-value: 2.8E-7 score: 40.2 coord: 62..100 e-value: 3.1E-9 score: 46.7
IPR002172	Low-density lipoprotein (LDL) receptor class A repeat	PFAM	PF00057	Ldl_recept_a	coord: 63..98 e-value: 1.5E-7 score: 31.5 coord: 20..58 e-value: 1.9E-8 score: 34.4
IPR002172	Low-density lipoprotein (LDL) receptor class A repeat	PROSITE	PS50068	LDLRA_2	coord: 20..59 score: 11.05
IPR002172	Low-density lipoprotein (LDL) receptor class A repeat	PROSITE	PS50068	LDLRA_2	coord: 62..99 score: 12.55
IPR002172	Low-density lipoprotein (LDL) receptor class A repeat	CDD	cd00112	LDLa	coord: 63..98 e-value: 1.05336E-8 score: 49.1274
IPR002172	Low-density lipoprotein (LDL) receptor class A repeat	CDD	cd00112	LDLa	coord: 21..58 e-value: 2.32803E-7 score: 45.2754
IPR000033	LDLR class B repeat	SMART	SM00135	LY_2	coord: 404..446 e-value: 0.049 score: 22.8 coord: 316..356 e-value: 4.9 score: 12.6 coord: 357..403 e-value: 3.3E-4 score: 30.0 coord: 453..493 e-value: 16.0 score: 8.4
IPR000033	LDLR class B repeat	PFAM	PF00058	Ldl_recept_b	coord: 377..421 e-value: 1.2E-7 score: 32.1
IPR000033	LDLR class B repeat	PROSITE	PS51120	LDLRB	coord: 470..485 score: 6.884
IPR000033	LDLR class B repeat	PROSITE	PS51120	LDLRB	coord: 377..423 score: 12.43
IPR000033	LDLR class B repeat	PROSITE	PS51120	LDLRB	coord: 334..376 score: 8.276
IPR000033	LDLR class B repeat	PROSITE	PS51120	LDLRB	coord: 424..443 score: 6.42
IPR000742	EGF-like domain	SMART	SM00181	egf_5	coord: 147..184 e-value: 6.7E-4 score: 29.0 coord: 188..223 e-value: 14.0 score: 14.4
IPR001881	EGF-like calcium-binding domain	SMART	SM00179	egfca_6	coord: 144..184 e-value: 8.6E-4 score: 26.6 coord: 185..223 e-value: 0.0088 score: 18.4
IPR011042	Six-bladed beta-propeller, TolB-like	GENE3D	G3DSA:2.120.10.30		coord: 230..559 e-value: 3.6E-44 score: 153.0
None	No IPR available	PFAM	PF14670	FXa_inhibition	coord: 148..183 e-value: 9.7E-9 score: 35.4
None	No IPR available	GENE3D	G3DSA:2.10.25.10		coord: 146..221 e-value: 5.6E-12 score: 47.5
None	No IPR available	PANTHER	PTHR22722	FAMILY NOT NAMED	coord: 20..508
None	No IPR available	SIGNALP_EUK	SignalP-noTM	SignalP-noTM	coord: 1..19 score: 0.807
None	No IPR available	SUPERFAMILY	SSF57196	EGF/Laminin	coord: 148..191
None	No IPR available	SUPERFAMILY	SSF63825	YWTD domain	coord: 304..499
None	No IPR available	TMHMM	TMhelix		coord: 567..589
IPR036055	LDL receptor-like superfamily	GENE3D	G3DSA:4.10.400.10		coord: 67..98 e-value: 1.7E-9 score: 39.7
IPR036055	LDL receptor-like superfamily	GENE3D	G3DSA:4.10.400.10		coord: 18..66 e-value: 5.6E-10 score: 41.2
IPR036055	LDL receptor-like superfamily	SUPERFAMILY	SSF57424	LDL receptor-like module	coord: 57..99
IPR036055	LDL receptor-like superfamily	SUPERFAMILY	SSF57424	LDL receptor-like module	coord: 20..60
IPR040093	Low-density lipoprotein receptor class A domain-containing protein 1	PANTHER	PTHR22722:SF5	LOW-DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 1-RELATED	coord: 20..508
IPR023415	Low-density lipoprotein (LDL) receptor class A, conserved site	PROSITE	PS01209	LDLRA_1	coord: 76..98
IPR009030	Growth factor receptor cysteine-rich domain superfamily	SUPERFAMILY	SSF57184	Growth factor receptor domain	coord: 187..223

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low-density lipoprotein receptor-related protein 2

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 9

Owlery

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