Glutamate receptor ionotropic kainate 3

Overview
NameGlutamate receptor ionotropic kainate 3
Smed IDSMED30020437
Length (bp)3085
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Glutamate receptor ionotropic kainate 3 (SMED30020437) t-SNE clustered cells

Violin plots show distribution of expression levels for Glutamate receptor ionotropic kainate 3 (SMED30020437) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Glutamate receptor ionotropic kainate 3 (SMED30020437) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Glutamate receptor ionotropic kainate 3 (SMED30020437) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30020437

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30020437h1SMcG0004826 dd_Smed_v4_13705_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30020437h1SMcG0004826 dd_Smed_v4_13705_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30020437h1SMcG0004826 dd_Smed_v4_13705_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30020437h1SMcG0004826 dd_Smed_v6_13705_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Human
Match: GRIK2 (glutamate ionotropic receptor kainate type subunit 2 [Source:HGNC Symbol;Acc:HGNC:4580])

HSP 1 Score: 427.557 bits (1098), Expect = 1.773e-134
Identity = 269/770 (34.94%), Postives = 426/770 (55.32%), Query Frame = 3
Query:  231 SVAVQNANSQLMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLL---NQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAA-----PAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNE-EAQRKQYNLSVMELTENGFMKKGYWN-GNNFVIFPPKSKSPVTETNEVI-KPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCD-DNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMEN-NPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWW 2501
            +V   N N  L+  N +    T+ ++   SF   +KAC+ L  G+ A+  P     +  + S  N   +PH+ T+ +   S       + LYP+  + +  I   + Q   W  + +++     +++ + L+   +++    K+RQ +  D K  K  L+++ K  K  H + D  +      L       +    + +IFT  D   LD+  ++ +  VN+T F ++N        T +  ++S++E  +   +L      ++ LL        A++ D+++V+    + + +   +    ++C  +  W  G    + I    H  GLTGRI FN+    R  ++L V+ L E G  K G W+  +   +   +   P   T+ +  + L VTTI+  P+V +K +   +  +D     + G+CIDLL E+   L   + I LV+D KYG         D + +WNGM+ ELI  +ADL VAP+ I+Y REKV+DF+ PFM+LG+SIL+  P    PG+FSFL+PLSP +W+Y++ AY+GVS +++ I+  +PYEW   HPC+ D+   +N F +LNS WF V ALM+QG E  P+A STR+V   WWFFTLIIIS+YTANLAAFLTVE++  PI S +DL  Q  I+YG ++ GA+  FF+++ I TY KM  +M +    V+V+S EEG+ +VL S+  YAFL+ES   ++  +R C L ++G ++DSKGYG+G P GSP RDK+T +IL+LQ+  KL  +  KWW
Sbjct:   22 AVNTINRNRTLLP-NTTLTYDTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDFSSLSRAILDLV-QFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQ-LPADTKDAKPLLKEM-KRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYSG-VNMTGFRILN--------TENTQVSSIIEK-WSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVS---VAVQQFPQMTVSSLQCNRHKPWRFGTRFMSLIKEA-HWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPASGLNMTESQKGKPANITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDR----FEGYCIDLLRELSTILGFTYEIRLVEDGKYGA------QDDANGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGIQRVLTSD--YAFLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKWW 761          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Human
Match: GRIK2 (glutamate ionotropic receptor kainate type subunit 2 [Source:HGNC Symbol;Acc:HGNC:4580])

HSP 1 Score: 428.328 bits (1100), Expect = 2.593e-134
Identity = 272/787 (34.56%), Postives = 433/787 (55.02%), Query Frame = 3
Query:  231 SVAVQNANSQLMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLL---NQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAA-----PAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNE-EAQRKQYNLSVMELTENGFMKKGYWN-GNNFVIFPPKSKSPVTETNEVI-KPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCD-DNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMEN-NPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKGSI 2552
            +V   N N  L+  N +    T+ ++   SF   +KAC+ L  G+ A+  P     +  + S  N   +PH+ T+ +   S       + LYP+  + +  I   + Q   W  + +++     +++ + L+   +++    K+RQ +  D K  K  L+++ K  K  H + D  +      L       +    + +IFT  D   LD+  ++ +  VN+T F ++N        T +  ++S++E  +   +L      ++ LL        A++ D+++V+    + + +   +    ++C  +  W  G    + I    H  GLTGRI FN+    R  ++L V+ L E G  K G W+  +   +   +   P   T+ +  + L VTTI+  P+V +K +   +  +D     + G+CIDLL E+   L   + I LV+D KYG         D + +WNGM+ ELI  +ADL VAP+ I+Y REKV+DF+ PFM+LG+SIL+  P    PG+FSFL+PLSP +W+Y++ AY+GVS +++ I+  +PYEW   HPC+ D+   +N F +LNS WF V ALM+QG E  P+A STR+V   WWFFTLIIIS+YTANLAAFLTVE++  PI S +DL  Q  I+YG ++ GA+  FF+++ I TY KM  +M +    V+V+S EEG+ +VL S+  YAFL+ES   ++  +R C L ++G ++DSKGYG+G P GSP RDK+T +IL+LQ+  KL  +  KWW      E  ++KE  ++
Sbjct:   60 AVNTINRNRTLLP-NTTLTYDTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDFSSLSRAILDLV-QFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQ-LPADTKDAKPLLKEM-KRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYSG-VNMTGFRILN--------TENTQVSSIIEK-WSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVS---VAVQQFPQMTVSSLQCNRHKPWRFGTRFMSLIKEA-HWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPASGLNMTESQKGKPANITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDR----FEGYCIDLLRELSTILGFTYEIRLVEDGKYGA------QDDANGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGIQRVLTSD--YAFLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEE-ESKEASAL 815          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Human
Match: GRIK2 (glutamate ionotropic receptor kainate type subunit 2 [Source:HGNC Symbol;Acc:HGNC:4580])

HSP 1 Score: 428.328 bits (1100), Expect = 2.632e-134
Identity = 267/770 (34.68%), Postives = 427/770 (55.45%), Query Frame = 3
Query:  231 SVAVQNANSQLMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLL---NQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAA-----PAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNE-EAQRKQYNLSVMELTENGFMKKGYWN-GNNFVIFPPKSKSPVTETNEVI-KPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCD-DNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMEN-NPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWW 2501
            +V   N N  L+  N +    T+ ++   SF   +KAC+ L  G+ A+  P     +  + S  N   +PH+ T+ +   S       + LYP+  + +  I   + Q   W  + +++     +++ + L+   +++    K+RQ +  D K  K  L+++ + ++  H + D  +      L       +    + +IFT  D   LD+  ++ +  VN+T F ++N        T +  ++S++E  +   +L      ++ LL        A++ D+++V+    + + +   +    ++C  +  W  G    + I    H  GLTGRI FN+    R  ++L V+ L E G  K G W+  +   +   +   P   T+ +  + L VTTI+  P+V +K +   +  +D     + G+CIDLL E+   L   + I LV+D KYG         D + +WNGM+ ELI  +ADL VAP+ I+Y REKV+DF+ PFM+LG+SIL+  P    PG+FSFL+PLSP +W+Y++ AY+GVS +++ I+  +PYEW   HPC+ D+   +N F +LNS WF V ALM+QG E  P+A STR+V   WWFFTLIIIS+YTANLAAFLTVE++  PI S +DL  Q  I+YG ++ GA+  FF+++ I TY KM  +M +    V+V+S EEG+ +VL S+  YAFL+ES   ++  +R C L ++G ++DSKGYG+G P GSP RDK+T +IL+LQ+  KL  +  KWW
Sbjct:   22 AVNTINRNRTLLP-NTTLTYDTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDFSSLSRAILDLV-QFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQ-LPADTKDAKPLLKEMKRGKEF-HVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYSG-VNMTGFRILN--------TENTQVSSIIEK-WSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVS---VAVQQFPQMTVSSLQCNRHKPWRFGTRFMSLIKEA-HWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPASGLNMTESQKGKPANITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDR----FEGYCIDLLRELSTILGFTYEIRLVEDGKYGA------QDDANGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGIQRVLTSD--YAFLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKWW 761          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Human
Match: GRIK2 (glutamate ionotropic receptor kainate type subunit 2 [Source:HGNC Symbol;Acc:HGNC:4580])

HSP 1 Score: 427.943 bits (1099), Expect = 2.679e-134
Identity = 267/770 (34.68%), Postives = 427/770 (55.45%), Query Frame = 3
Query:  231 SVAVQNANSQLMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLL---NQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAA-----PAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNE-EAQRKQYNLSVMELTENGFMKKGYWN-GNNFVIFPPKSKSPVTETNEVI-KPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCD-DNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMEN-NPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWW 2501
            +V   N N  L+  N +    T+ ++   SF   +KAC+ L  G+ A+  P     +  + S  N   +PH+ T+ +   S       + LYP+  + +  I   + Q   W  + +++     +++ + L+   +++    K+RQ +  D K  K  L+++ + ++  H + D  +      L       +    + +IFT  D   LD+  ++ +  VN+T F ++N        T +  ++S++E  +   +L      ++ LL        A++ D+++V+    + + +   +    ++C  +  W  G    + I    H  GLTGRI FN+    R  ++L V+ L E G  K G W+  +   +   +   P   T+ +  + L VTTI+  P+V +K +   +  +D     + G+CIDLL E+   L   + I LV+D KYG         D + +WNGM+ ELI  +ADL VAP+ I+Y REKV+DF+ PFM+LG+SIL+  P    PG+FSFL+PLSP +W+Y++ AY+GVS +++ I+  +PYEW   HPC+ D+   +N F +LNS WF V ALM+QG E  P+A STR+V   WWFFTLIIIS+YTANLAAFLTVE++  PI S +DL  Q  I+YG ++ GA+  FF+++ I TY KM  +M +    V+V+S EEG+ +VL S+  YAFL+ES   ++  +R C L ++G ++DSKGYG+G P GSP RDK+T +IL+LQ+  KL  +  KWW
Sbjct:   22 AVNTINRNRTLLP-NTTLTYDTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDFSSLSRAILDLV-QFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQ-LPADTKDAKPLLKEMKRGKEF-HVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYSG-VNMTGFRILN--------TENTQVSSIIEK-WSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVS---VAVQQFPQMTVSSLQCNRHKPWRFGTRFMSLIKEA-HWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPASGLNMTESQKGKPANITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDR----FEGYCIDLLRELSTILGFTYEIRLVEDGKYGA------QDDANGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGIQRVLTSD--YAFLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKWW 761          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Human
Match: GRIK2 (glutamate ionotropic receptor kainate type subunit 2 [Source:HGNC Symbol;Acc:HGNC:4580])

HSP 1 Score: 428.713 bits (1101), Expect = 5.290e-134
Identity = 270/787 (34.31%), Postives = 434/787 (55.15%), Query Frame = 3
Query:  231 SVAVQNANSQLMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLL---NQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAA-----PAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNE-EAQRKQYNLSVMELTENGFMKKGYWN-GNNFVIFPPKSKSPVTETNEVI-KPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCD-DNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMEN-NPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKGSI 2552
            +V   N N  L+  N +    T+ ++   SF   +KAC+ L  G+ A+  P     +  + S  N   +PH+ T+ +   S       + LYP+  + +  I   + Q   W  + +++     +++ + L+   +++    K+RQ +  D K  K  L+++ + ++  H + D  +      L       +    + +IFT  D   LD+  ++ +  VN+T F ++N        T +  ++S++E  +   +L      ++ LL        A++ D+++V+    + + +   +    ++C  +  W  G    + I    H  GLTGRI FN+    R  ++L V+ L E G  K G W+  +   +   +   P   T+ +  + L VTTI+  P+V +K +   +  +D     + G+CIDLL E+   L   + I LV+D KYG         D + +WNGM+ ELI  +ADL VAP+ I+Y REKV+DF+ PFM+LG+SIL+  P    PG+FSFL+PLSP +W+Y++ AY+GVS +++ I+  +PYEW   HPC+ D+   +N F +LNS WF V ALM+QG E  P+A STR+V   WWFFTLIIIS+YTANLAAFLTVE++  PI S +DL  Q  I+YG ++ GA+  FF+++ I TY KM  +M +    V+V+S EEG+ +VL S+  YAFL+ES   ++  +R C L ++G ++DSKGYG+G P GSP RDK+T +IL+LQ+  KL  +  KWW      E  ++KE  ++
Sbjct:   60 AVNTINRNRTLLP-NTTLTYDTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDFSSLSRAILDLV-QFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQ-LPADTKDAKPLLKEMKRGKEF-HVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYSG-VNMTGFRILN--------TENTQVSSIIEK-WSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVS---VAVQQFPQMTVSSLQCNRHKPWRFGTRFMSLIKEA-HWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPASGLNMTESQKGKPANITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDR----FEGYCIDLLRELSTILGFTYEIRLVEDGKYGA------QDDANGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGIQRVLTSD--YAFLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEE-ESKEASAL 815          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Celegans
Match: glr-3 (GLutamate Receptor family (AMPA) [Source:UniProtKB/TrEMBL;Acc:Q21415])

HSP 1 Score: 349.747 bits (896), Expect = 1.011e-105
Identity = 244/776 (31.44%), Postives = 424/776 (54.64%), Query Frame = 3
Query:  279 SFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLS------SFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLL--NQFE---YHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSL--INDSLVTSLRTR--HKNLNSLMENIFESRKLSKKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNEEAQRKQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKSPVTETNEVI---KPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCDDNGSRQ---NQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEK 2543
            SF+IV  +++ NG FSV    CN L  G  A+I P  E    HL+      S ++  ++P +      P   +++     L+P+ +A +  +  +I + E W +++++ +  + +++   ++    F+   +  ++ +  HGD   N+  L+ +         ++++P  +   FL   +  ++ G  + ++  D D   +D+   +     NIT+F +  +N   +  +R    HK+          S +L KK    T      +I ID++ +L    IR +K   ++ +P +C   ++W  G  +       + + G++G + +    +R  Y L V   T + F K   W+     I   ++      + ++    K L+++  +  PFV    N            ++ G+CIDLL++I   L+  ++I  V+DN YG+    E+N     KW+GM+GEL   +ADL VA +TISY R +V+DFT P+M LG+SILF  P+      F F+ PLS  VW+   ++Y  VS+ I+ I+ ++PYE  Q    +DNG  +   NQF++ NS WFTV +LM+QG E CP+A+STR+++  WWFF LI+IS+YTANLAA LT  ++  PI++ +DL  Q  IKYGTL  G++ +FF  + I+TY++M + M ++P + V+S++EG+ +V  S+  YA+L+ES+M +Y  ER+C L+++G ++D KGYGIG P GSP R+ ++ +IL+LQ+  +L+ L  KWW + ++   C+  ++
Sbjct:   60 SFKIVGISIE-NGLFSV----CNCLILGASAIILP--EQYDGHLAAAAIVQSIADNTNVPCVSLHLSPPTRPSTH-----LHPHLNAKSLAVAAFIKR-EKWKDVVVVFEEPDELLEITDMITAGHFDPDSFSSQLVRLKHGDDYGNE--LKHIKNKLDRYRIVINIPLQKALHFLEQAANMSMCGVLYHYVVMDMDLVTVDIDSIRGIEDCNITSFGVHDVNSEYIEDIRQEIVHKS----------SIRLPKKGVPYTT-----SIWIDTLRLL----IRSMKSIQIWDEP-RC--GSSWKSGSDIKKRFFE-NPLAGISGDLHWAPSGERSNYTLHVYRRTLS-FQKFAEWSSRTRRIASSEAVVIANSSEKLTLEGKHLKISVYLEAPFVMITSNG-----------SYEGYCIDLLHKIANILKFTYTIQKVRDNAYGS---KESNG----KWSGMVGELQRGDADLAVASLTISYGRSEVIDFTVPYMHLGISILFKKPRIRDSDWFKFMDPLSTQVWIMTFASYFVVSVAIWIIAKISPYE--QFERDEDNGQYKPVDNQFSLRNSFWFTVCSLMQQGSELCPRAASTRLLTGIWWFFALILISSYTANLAAVLTTRRMETPIENADDLAAQTKIKYGTLGRGSTMSFFNESKIETYERMWQLMSSSPGLFVQSSKEGIARVKSSD--YAYLMESSMLEYAVERDCELMQIGGLIDQKGYGIGLPKGSPYRELISTAILRLQEKTELTELKEKWWKDKSVV--CEQPKR 772          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Celegans
Match: glr-5 (GLutamate Receptor family (AMPA) [Source:UniProtKB/TrEMBL;Acc:O01623])

HSP 1 Score: 330.872 bits (847), Expect = 6.986e-98
Identity = 278/926 (30.02%), Postives = 460/926 (49.68%), Query Frame = 3
Query:  165 SKIYLTIGVIFEANDDVSRKVVSVAVQNANSQLMRYNY--SFRIVTETVDDNGSFSVIRKACNLLQ-NGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLLNQFEY---HFKMRQWIHGDLKKNKEFLRKLAKSRK-HK-------HFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAAPAIIIDSI----NVLMEGLIRLIKLQPV-FTQPMKCTTNT-TWNQGISLFNAITSVDHMYGLTGRIV-FNEEAQRKQYNLSVMELTENGFMKK-GYWN--GNNFVIFPPKSKSPVTETNEV---IKP-LRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEW---------LQIHPCDDNGSRQ-------NQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKGSIPTALDVHQXXXXXXXXXXXXXXASMVSVIELYVTYCEGTCKWNVPFHIYFQKELQFAVRFMS----SSKKPLNTYNVDNKSREDCL 2798
            S I   IG IF   +D     +  AV+ +   L +        +V E +D    +  I+KAC +L+ + +VAL+       +  L   ++   IP L                I  +P    +  ++  +      W  ++++++ D  I + E LL   EY    F + +   GD  K    +++L + R  HK         LVD+       FL+      L    H F+ T+ +   +D+ +F+ N+   I+ +  ++ + +T  R    N +   E+I E   +   +  N  ++ A     D++    NV  E L   +++  V  T   K + N+  +  G SL + I   D ++GL+G +   N    +  +++ +  L  +G +   G+W    N  V     SK+ +    +V   +KP  RVTTI+  P+V  K N  ++  +      + GFCIDLL E+  DL   ++IH VKD KYG    N+   +GS  W+GM+GE++  EA++ VAP+T++Y R + VDFT PF+SLG+SIL+  P  + P LFSFL+PLS  +W  + ++ I V+L +YF+++VTPYEW          + HP     + Q       N ++  N++W+ ++ +++ G +F P+A STR++   WW F L+IIS YTANLAA LTV +  +PIK+++DL NQ TI YGT++GG++  FF+ + I  + KM +YM++  DV V S  +GV++ L  N  YA+L+ES   +Y  ++ C L ++G +L SKGYGI     S   D++++ IL   K   +     KWW                   AL ++ V G+F+ LGVG + A++V + EL         K   PF      EL+FA+   S     S++ ++T N +   + + L
Sbjct:   21 SCIAYKIGAIFREREDAH---IEAAVRYSVEWLSQRGIYGDIDLVIEYIDVLDHYDAIKKACKMLEKDHIVALLGGSHAALNAQLERITDDLDIPFLTAIDDLRTDMGK--SKIDFWPRPQLFEAVVDMFTHW--RWNRIVLVYEGDERIRRLEQLLESEEYASIRFYLIKVHDGDYMKAARQVKELEECRLLHKKDCSEFSRLLVDMNPEHTYTFLLASLQMGLIELKHWFLLTNMELSTMDMELFRYNHARFISPYP-VDSTFLTENRDAF-NFSHFKEHITEKWAMKTDNSRNLKMMEA-VFTFDAVYAFANVFNE-LSSHMQMNDVPQTLCRKSSRNSRKYQHGRSLIDNIVHND-LHGLSGDLRRLNGHPLKSNFSMRIQLLGYSGRLDDIGFWEPATNVHVNMSGDSKAQLQRNVQVSDELKPHFRVTTIMERPYVMLKKNHYELDANSK----FEGFCIDLLAELSKDLGFTYTIHAVKDGKYG----NDKYGNGS--WDGMMGEILRGEAEMAVAPLTVNYRRSEAVDFTKPFLSLGISILYKVPDDQQPDLFSFLNPLSWQIWTAIATSIITVTLGMYFVANVTPYEWNLNFSCCTAHEPHPAAAFATNQEAPIVMSNNYSFWNTVWYVLSTMLKGGCDFGPRAVSTRLLGGTWWVFYLVIISAYTANLAAVLTVSRPYIPIKNLDDLANQTTISYGTIRGGSTMQFFQESRIAAHVKMWQYMKDK-DVFVTSNGKGVERALSMN--YAYLMESTSLEYETQQNCNLTQIGGVLGSKGYGIALAKKSEWTDRISRQILLYAKRGIIEMKKTKWWRSKGAACASTASAVKHDRFALSMYNVAGLFITLGVGIVLAAIVVIFELIHRCHHIAKKEGKPFLEELLYELRFALNMNSLSDHRSRQKMSTCNSNGNGKPNHL 921          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Celegans
Match: glr-4 (GLutamate Receptor family (AMPA) [Source:UniProtKB/TrEMBL;Acc:Q17697])

HSP 1 Score: 320.857 bits (821), Expect = 1.055e-94
Identity = 237/761 (31.14%), Postives = 391/761 (51.38%), Query Frame = 3
Query:  336 KACNLLQNGLVALIAP--LSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIII-HKSD----NCIMKYEYLLNQF--EYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEI-RDFLIMVSTHNLTGPAHSFIFTDWDARILDL---SVFKINNKVNITAFSLI-NDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQP-MKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNEEAQRKQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKS-------PVTETNEVIKPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXX--XXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCDDNG-----SRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYME-NNPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPC 2528
            + C ++Q G+VA++     SE  S+ + S  + F+IP L  +      S S  + + L P+  A A    +++  +   G ++   H SD    + +M+Y+ +++      H K+R+ +  +    + FL+ +    K  + ++      +  + L      N+  P  S++FT+ D  +L+    +++  +   NIT   L+ ND +                             + T L    A+  +++ V+   + R+ +L     Q  + C ++  W+ G  +   I  +     LTG + F    +R       +    + F+K G W+      F  +  +       P +E  E +  LRV   +  PFV             T  + + GFCIDLLNE+   L+ N++I  V+D  YG         D S +WNG+IG L   EADL ++ +TI+Y R +VVDFT PFM LG+SIL     +E       +FL PLS  VW+ ++ +Y  VS  ++ ++  +PYEW  +   D+       +++NQF +LNS WFT+ +LM+QG +  P+A++TR+++  WW FT IIIS+YTA LAAFLTVE++  PI+S +DL NQ+ I+YG LK G++  FF  + I  Y++M   ME ++P V V S+ EG+ +V   +G YA+++ES+M +YY ER+C L  +G +LDSKGYGI  P GSPLRD +++++L+LQ+   L  L +KWW +      C
Sbjct:   79 RMCEIMQQGIVAVVLSNEESEQDSQLIKSMCHYFNIPCLSLQSTSLRDSVSDFVTL-LGPSRGAGARATSEFLDSMRWTGFLLAYQHGSDLEDLSPLMQYKQIVDTGGRRIHIKIRR-LPNNTDDYEPFLKYVKTRLKQTNIIIHSNNITVLYNLLQQARGLNMAEPPFSYVFTNTDLSLLEDFLNNMYGASFHCNITGLQLVKNDPM-----------------------------MKTQL----ALTSEAVYVVGMSIYRMRELGHAPRQSSIMCDSHDIWSDGRIMNEGIRKLKLRNQLTGDVQFKSNGERDDIMYHGVGRINSQFVKLGNWSEKRGWNFDSRYANRWEFDIDPDSEDLEGLH-LRVVVYLEEPFVI-----------KTGENQYEGFCIDLLNEMTQVLKFNYTIIEVQDGTYGI-------EDESGRWNGIIGALQRHEADLSLSAVTITYSRAEVVDFTLPFMHLGISILLARTSEETDKGSLWTFLEPLSLTVWISLLISYCIVSYSMHILAKFSPYEWYNLERIDERDFENIKNQKNQFTVLNSFWFTMGSLMQQGSDVIPRAAATRLIAVVWWMFTQIIISSYTAQLAAFLTVERMSTPIESTQDLANQQKIRYGVLKSGSTMDFFRESKIPMYERMWSVMESSSPGVFVNSSREGIARV--KSGGYAYMMESSMLEYYLERDCELQSIGGLLDSKGYGIALPKGSPLRDILSRTVLQLQERTILEALKNKWWRDRREGPSC 783          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Celegans
Match: glr-4 (GLutamate Receptor family (AMPA) [Source:UniProtKB/TrEMBL;Acc:Q17697])

HSP 1 Score: 320.857 bits (821), Expect = 3.892e-94
Identity = 237/761 (31.14%), Postives = 391/761 (51.38%), Query Frame = 3
Query:  336 KACNLLQNGLVALIAP--LSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIII-HKSD----NCIMKYEYLLNQF--EYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEI-RDFLIMVSTHNLTGPAHSFIFTDWDARILDL---SVFKINNKVNITAFSLI-NDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQP-MKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNEEAQRKQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKS-------PVTETNEVIKPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXX--XXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCDDNG-----SRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYME-NNPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPC 2528
            + C ++Q G+VA++     SE  S+ + S  + F+IP L  +      S S  + + L P+  A A    +++  +   G ++   H SD    + +M+Y+ +++      H K+R+ +  +    + FL+ +    K  + ++      +  + L      N+  P  S++FT+ D  +L+    +++  +   NIT   L+ ND +                             + T L    A+  +++ V+   + R+ +L     Q  + C ++  W+ G  +   I  +     LTG + F    +R       +    + F+K G W+      F  +  +       P +E  E +  LRV   +  PFV             T  + + GFCIDLLNE+   L+ N++I  V+D  YG         D S +WNG+IG L   EADL ++ +TI+Y R +VVDFT PFM LG+SIL     +E       +FL PLS  VW+ ++ +Y  VS  ++ ++  +PYEW  +   D+       +++NQF +LNS WFT+ +LM+QG +  P+A++TR+++  WW FT IIIS+YTA LAAFLTVE++  PI+S +DL NQ+ I+YG LK G++  FF  + I  Y++M   ME ++P V V S+ EG+ +V   +G YA+++ES+M +YY ER+C L  +G +LDSKGYGI  P GSPLRD +++++L+LQ+   L  L +KWW +      C
Sbjct:   79 RMCEIMQQGIVAVVLSNEESEQDSQLIKSMCHYFNIPCLSLQSTSLRDSVSDFVTL-LGPSRGAGARATSEFLDSMRWTGFLLAYQHGSDLEDLSPLMQYKQIVDTGGRRIHIKIRR-LPNNTDDYEPFLKYVKTRLKQTNIIIHSNNITVLYNLLQQARGLNMAEPPFSYVFTNTDLSLLEDFLNNMYGASFHCNITGLQLVKNDPM-----------------------------MKTQL----ALTSEAVYVVGMSIYRMRELGHAPRQSSIMCDSHDIWSDGRIMNEGIRKLKLRNQLTGDVQFKSNGERDDIMYHGVGRINSQFVKLGNWSEKRGWNFDSRYANRWEFDIDPDSEDLEGLH-LRVVVYLEEPFVI-----------KTGENQYEGFCIDLLNEMTQVLKFNYTIIEVQDGTYGI-------EDESGRWNGIIGALQRHEADLSLSAVTITYSRAEVVDFTLPFMHLGISILLARTSEETDKGSLWTFLEPLSLTVWISLLISYCIVSYSMHILAKFSPYEWYNLERIDERDFENIKNQKNQFTVLNSFWFTMGSLMQQGSDVIPRAAATRLIAVVWWMFTQIIISSYTAQLAAFLTVERMSTPIESTQDLANQQKIRYGVLKSGSTMDFFRESKIPMYERMWSVMESSSPGVFVNSSREGIARV--KSGGYAYMMESSMLEYYLERDCELQSIGGLLDSKGYGIALPKGSPLRDILSRTVLQLQERTILEALKNKWWRDRREGPSC 783          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Celegans
Match: glr-2 (Glutamate receptor 2 [Source:UniProtKB/Swiss-Prot;Acc:Q10914])

HSP 1 Score: 307.375 bits (786), Expect = 4.886e-89
Identity = 243/772 (31.48%), Postives = 385/772 (49.87%), Query Frame = 3
Query:  534 IFQYITQIEAWGEMIIIHKSDNCIMKYEYLLNQF-----EYHFKMRQWIH-GDLKKNKEFLRKLAKSRKHKHFL--------VDLPY-----------WEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLL-AAPAIIIDSINVLMEGLI-------------RLIKLQ-------PVFTQPMKCTTNT----TWNQGISLFNAITSV---DHMYGLTGRIVFNE-EAQRKQYNLSVMEL-----TENGFMKKGYW-NGNNFVI----FPPKSKSPVTETNEVIKPLR-------VTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLR-LNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCDDNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYM-----------------ENNPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYK-ERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDT-KEKGSIPTALDVHQ 2576
            +  YI Q + W +++ IH   N       + +       +Y   +  ++   D +  KEFL +  +    +H L        +D P            +  R FL  +    L    + ++F+++D    DLS F          FSLIN   +T  R   KN    ++   E   + +  F NT+ +  A A   D+I V  + L                ++ Q        ++ +P +  T +    T+  G  +  AI  V   D    LTGRI F++   +R  ++  ++E+     + N   ++  W  G  F++    +  + K   ++T + I P +       V T++  PFV  K  +P   E   + D + G+CIDLLN +  ++    + + +   NKYG+        DGS  W+GMIG L+++ AD+ VAP+TI+ ERE+ VDF+ PFM+ G+SI+   P+K+   +FSF+ PL   +W++ +S+Y GVSL I+ +S  +PYE  +I       +  N+F + NSLWFT+AA M+QG +  P+A S R+ SS WWFFTLII+S+YTANLAAFLT+E++  PI+SVEDL NQ  I YG  +GG++ AFFE +++  YKKM  +M                   +  + V S  +G++KV  S GKYAFLLE   N+Y    R C  ++VG  L++ GYGI    G+PLR  +  +IL L +  +L  L +KWW +      CDT    G   ++L++ +
Sbjct:  152 LIDYI-QYKGWRDVVYIHDGKNADRTLRTMFSYLHEKSPKYQLFVDNYVAPSDEEMFKEFLNEFHRRISTQHTLKSNDSSEEIDEPIPVNVIVDLEGSYRTRAFLRALEESVLVKKEYHYVFSNFDVDETDLSGFH---------FSLIN---ITIFRIFDKNNKKFLKTRAEFHDVYRGGFSNTDSIPTAAAFAHDAILVAGKALQIAMNEHGKGIFDKSFVRHQLFNRGRKGLYCRPHEDQTESRQFETFEHGKKIAEAIKKVVLTDKDGTLTGRIQFDKVTGKRTNFSAEIVEIKPGVNSLNSIWERFQWAEGEGFLLGGERYVQEKKKDSSQTRKGILPSKPWQLRFNVVTVLVKPFVMLKRRNPGEPELKGN-DRFEGYCIDLLNLLAKNITGFEYDVFISDGNKYGS-----RQADGS--WDGMIGYLLNETADVAVAPLTITQERERAVDFSKPFMTTGISIMIKKPEKQEFNIFSFMEPLGMTIWIFTLSSYFGVSLTIFLVSWFSPYE-KRIEFKRGEFTVTNEFTLYNSLWFTLAAFMQQGTDILPRAVSGRIASSCWWFFTLIIVSSYTANLAAFLTLERMTPPIESVEDLANQNKILYGVNEGGSTAAFFEDSIVPLYKKMWNFMVSTTQKQIELEKQSITNSTSNRIFVSSYADGIEKVRTSKGKYAFLLEETTNNYESGRRPCDTMKVGQNLNTLGYGIATKIGNPLRVSLNLAILYLSEKGELKKLENKWWYDRG---QCDTGTSDGGTSSSLNLSK 898          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Fly
Match: KaiR1D (gene:FBgn0038837 transcript:FBtr0083987)

HSP 1 Score: 442.195 bits (1136), Expect = 4.408e-140
Identity = 295/811 (36.37%), Postives = 440/811 (54.25%), Query Frame = 3
Query:  177 LTIGVIFEANDDVSRKVVSVAVQNANSQ---LMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPN--CDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLLNQF---EYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNEEAQRKQYNLSVMELTENGFMKKGYWN-----GNNFV-IFPPKSKSPVTETNEVIKPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCDDNGSR-QNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMEN-NPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKGSIPTA 2561
            + IG +F   DD        AV   N+    L R     +I  E +    SF   ++ C LL  G+ A+  P S   + H+ S  +   IPHL  +  +     S  +N+  +PN    AY +I+  +      W    II+++++ I++ + LL       +   +RQ    D    +  L+++ K+    H ++D     I + L       +    HS++ T  D   ++L  F+     NIT F LIN+ +V+ +  R  +++   + +  S  L       T + +  A++ D++++  + L  L   Q +   P+ C   +TW  G SL N +  V+ M GLT  I F+ +  R  + L ++ELT  G  K G WN     G NF   F  K +    E N   K L VTTI+S P+   K+++  +  +D     + G+ +DL++EI   L  N+ I LV D  YG++  N+     + +WNGMI EL+ + ADL +A +TI++ERE+ VDFTTPFM+LG+SIL+  P K+ P LFSFLSPLS  VW+Y+ +AY+GVS++++ ++  TPYEW      D +G + ++QF +LN +WF + +LM+QG +F P+A STRMV+  WWFFTLI+IS+YTANLAAFLTVE++  PI+S EDL  Q  IKYG LKGG++ AFF  + I TY++M  +ME+  P V   S  EGV++V K  G YAFL+ES   +Y  ER C L +VG MLD+K YGI  P  SP R  +   ILKLQ+  KL  L  KWW E      C  +   S   A
Sbjct:   30 IKIGGLFHPADDHQELAFRQAVDRINADRSILPRSKLVAQI--ERISPFDSFHAGKRVCGLLNIGVAAIFGPQSSHTASHVQSICDNMEIPHLENRWDYRLRRESCLVNLYPHPNTLSKAYVDIVRHW-----GWKTFTIIYENNDGIVRLQELLKAHGMTPFPITVRQL--SDSGDYRPLLKQI-KNSAEAHIVLDCSTERIHEVLKQAQQIGMMSDYHSYLVTSLDLHTVNLDEFRYGG-TNITGFRLINEKIVSDV-VRQWSIDE--KGLLRSANL-------TTVRSETALMYDAVHLFAKALHDLDTSQQIDIHPISCDGQSTWQHGFSLINYMKIVE-MKGLTNVIKFDHQGFRTDFMLDIVELTPAGIRKIGTWNSTLPDGINFTRTFSQKQQE--IEANLKNKTLVVTTILSNPYCMRKESAIPLSGNDQ----FEGYAVDLIHEISKSLGFNYKIQLVPDGSYGSL--NKL----TGEWNGMIRELLEQRADLAIADLTITFEREQAVDFTTPFMNLGVSILYRKPIKQPPNLFSFLSPLSLDVWIYMATAYLGVSVLLFILAKFTPYEWPAY--TDAHGEKVESQFTLLNCMWFAIGSLMQQGCDFLPKALSTRMVAGIWWFFTLIMISSYTANLAAFLTVERMDSPIESAEDLAKQTRIKYGALKGGSTAAFFRDSKISTYQRMWSFMESARPSVFTASNGEGVERVAKGKGSYAFLMESTSIEYVTERNCELTQVGGMLDTKSYGIATPPNSPYRTAINSVILKLQEEGKLHILKTKWWKEKRGGGKCRVETSKSSSAA 804          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Fly
Match: CG11155 (gene:FBgn0039927 transcript:FBtr0333701)

HSP 1 Score: 416.772 bits (1070), Expect = 8.629e-130
Identity = 292/829 (35.22%), Postives = 445/829 (53.68%), Query Frame = 3
Query:  297 ETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLLNQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTN----LLAAPAIIIDSINVLMEGL--IRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNEEAQRKQYNLSVMELTENGFMKKGYWNGNNFV-IFPPKSKSPVTETNEVIKPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPC-DDNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNPD-VMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPC--DTKEKGSIPTALDVHQXXXXXXXXXXXXXXASMVSVIELYVTYCEGTCKWNVPFHIYFQKELQFAVRFMSSSKK 2750
            E V  + SF   +K C+ L+ G+ A+  P   + + H+ S    + IPH+  +     +S  + +N  LYP+      + ++ I     W ++ II++ D  +    +   + +    +RQ         ++ LR + +   +K  +VD     I+ F   +    +    + ++FT +D    DL  F+ N+ VNITAF L++   V S R         +E I + +KL        N    +    A++ DS+     GL  + L   Q  + + + CT++ TWN GISL+N I +     GLTG + F  E +R  + L +++L +    K GYW+ ++ V I  P   +   ++N     L V T    P+V  K++     ++ T    + GFCIDLL  I   +   + I LV DN YG  +  ETN      WNG++ EL+ + ADL VA MTI+Y RE V+DFT PFM+LG+ ILF  P  +   LFSF++PL+  +W+YV++AYI VS  ++ ++  +PYEW   HPC  +    +NQF+I NS WF     +RQG    P+A+STR+V   W+FF LIIIS+YTANLAAFLTVE+++ PI+S  DL  Q  I YGTL+GG++  FF  + I  Y+KM +YMEN    V V++ E+G+ +V++  G YAFL+ES M DY  +R+C L ++G +LDSKGYGI  P GSP RDK++ +IL+LQ+   +  L  KWW   N  + C  D K K S   AL V  +GGVF++L  G   A +V++ E      +     N        +EL+FA+    S  +
Sbjct:   86 EYVPRDDSFRTTKKVCSQLEAGVQAIFGPTDALLASHVQSICEAYDIPHIEGRIDLEYNSKEFSIN--LYPS-HTLLTLAYRDIMVYLNWTKVAIIYEEDYGLFNLMHSSTETKAEMYIRQ---ASPDSYRQVLRAIRQKEIYK-IIVDTNPSHIKSFFRSILQLQMNDHRYHYMFTTFDLETYDLEDFRYNS-VNITAFRLVD---VDSKR--------YLEVINQMQKLQHNGLDTINGSPYIQTESALMFDSVYAFANGLHFLNLDNHQNFYIKNLSCTSDQTWNDGISLYNQINAA-ITDGLTGTVQF-VEGRRNIFKLDILKLKQEKIQKVGYWHPDDGVNISDP---TAFYDSNIANITLVVMTREERPYVMVKED-----KNLTGNLRFEGFCIDLLKAIATQVGFQYKIELVPDNMYGVYIP-ETN-----SWNGIVQELMERRADLAVASMTINYARESVIDFTKPFMNLGIGILFKVPTSQPTRLFSFMNPLAIEIWLYVLAAYILVSFALFVMARFSPYEWKNPHPCYKETDIVENQFSISNSFWFITGTFLRQGSGLNPKATSTRIVGGCWFFFCLIIISSYTANLAAFLTVERMISPIESASDLAEQTEISYGTLEGGSTMTFFRDSKIGIYQKMWRYMENRKTAVFVKTYEDGIKRVME--GSYAFLMESTMLDYAVQRDCNLTQIGGLLDSKGYGIATPKGSPWRDKISLAILELQEKGIIQILYDKWWK--NTGDVCNRDDKSKESKANALGVENIGGVFVVLLCGLALAVVVAIFEFCWNSRKNLNTENQSLCSEMAEELRFAMHCHGSKSR 875          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Fly
Match: CG11155 (gene:FBgn0039927 transcript:FBtr0089195)

HSP 1 Score: 416.772 bits (1070), Expect = 8.629e-130
Identity = 292/829 (35.22%), Postives = 445/829 (53.68%), Query Frame = 3
Query:  297 ETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLLNQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTN----LLAAPAIIIDSINVLMEGL--IRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNEEAQRKQYNLSVMELTENGFMKKGYWNGNNFV-IFPPKSKSPVTETNEVIKPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPC-DDNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNPD-VMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPC--DTKEKGSIPTALDVHQXXXXXXXXXXXXXXASMVSVIELYVTYCEGTCKWNVPFHIYFQKELQFAVRFMSSSKK 2750
            E V  + SF   +K C+ L+ G+ A+  P   + + H+ S    + IPH+  +     +S  + +N  LYP+      + ++ I     W ++ II++ D  +    +   + +    +RQ         ++ LR + +   +K  +VD     I+ F   +    +    + ++FT +D    DL  F+ N+ VNITAF L++   V S R         +E I + +KL        N    +    A++ DS+     GL  + L   Q  + + + CT++ TWN GISL+N I +     GLTG + F  E +R  + L +++L +    K GYW+ ++ V I  P   +   ++N     L V T    P+V  K++     ++ T    + GFCIDLL  I   +   + I LV DN YG  +  ETN      WNG++ EL+ + ADL VA MTI+Y RE V+DFT PFM+LG+ ILF  P  +   LFSF++PL+  +W+YV++AYI VS  ++ ++  +PYEW   HPC  +    +NQF+I NS WF     +RQG    P+A+STR+V   W+FF LIIIS+YTANLAAFLTVE+++ PI+S  DL  Q  I YGTL+GG++  FF  + I  Y+KM +YMEN    V V++ E+G+ +V++  G YAFL+ES M DY  +R+C L ++G +LDSKGYGI  P GSP RDK++ +IL+LQ+   +  L  KWW   N  + C  D K K S   AL V  +GGVF++L  G   A +V++ E      +     N        +EL+FA+    S  +
Sbjct:   86 EYVPRDDSFRTTKKVCSQLEAGVQAIFGPTDALLASHVQSICEAYDIPHIEGRIDLEYNSKEFSIN--LYPS-HTLLTLAYRDIMVYLNWTKVAIIYEEDYGLFNLMHSSTETKAEMYIRQ---ASPDSYRQVLRAIRQKEIYK-IIVDTNPSHIKSFFRSILQLQMNDHRYHYMFTTFDLETYDLEDFRYNS-VNITAFRLVD---VDSKR--------YLEVINQMQKLQHNGLDTINGSPYIQTESALMFDSVYAFANGLHFLNLDNHQNFYIKNLSCTSDQTWNDGISLYNQINAA-ITDGLTGTVQF-VEGRRNIFKLDILKLKQEKIQKVGYWHPDDGVNISDP---TAFYDSNIANITLVVMTREERPYVMVKED-----KNLTGNLRFEGFCIDLLKAIATQVGFQYKIELVPDNMYGVYIP-ETN-----SWNGIVQELMERRADLAVASMTINYARESVIDFTKPFMNLGIGILFKVPTSQPTRLFSFMNPLAIEIWLYVLAAYILVSFALFVMARFSPYEWKNPHPCYKETDIVENQFSISNSFWFITGTFLRQGSGLNPKATSTRIVGGCWFFFCLIIISSYTANLAAFLTVERMISPIESASDLAEQTEISYGTLEGGSTMTFFRDSKIGIYQKMWRYMENRKTAVFVKTYEDGIKRVME--GSYAFLMESTMLDYAVQRDCNLTQIGGLLDSKGYGIATPKGSPWRDKISLAILELQEKGIIQILYDKWWK--NTGDVCNRDDKSKESKANALGVENIGGVFVVLLCGLALAVVVAIFEFCWNSRKNLNTENQSLCSEMAEELRFAMHCHGSKSR 875          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Fly
Match: Grik (gene:FBgn0038840 transcript:FBtr0335015)

HSP 1 Score: 403.29 bits (1035), Expect = 9.544e-125
Identity = 288/899 (32.04%), Postives = 479/899 (53.28%), Query Frame = 3
Query:   90 RMMPTISSFP--FLL--MLLGRPILSKELSKIYLTIGVIFEANDDVSRKVVSVAVQNANSQLMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLLNQFEYH---FKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNEEAQRKQYNLSVMELTENGFMKKGYWNGNNFVI----FPPKSKSPVTETNEVIKPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPC-DDNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLV-NQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKGSIPTALDVHQXXXXXXXXXXXXXXASMVSVIELYVTYCEGTCKWNVPFHIYFQKELQFAVRFMSSSK 2747
            +M+ T +SFP  F+L  +LL  P    E + +    G+++E  D    K+  +A+  AN +    +     V+ +++   SF   +K C +L+  LVA+  P S + +RH  S  +   +P L T+  F    A  P  I L+P+  A   +  + +     W    II++S   +     LL  +        +R++   DL  N   + +  ++     F+V      + +F        L    + +I  + D   +DL  ++ +   NIT   L++           + +  + + ++ES +  +   ++  L  + A++ D + +L E   + +  +PV    + C  ++ W++G +L N + S+  + GLTG I F+ E  R  + L V+EL  +G  K G W+G +        P  S  P   +  V K   V T +S P+   K+ S  ++ +D     + GF I+L++E+   L  +++  L +DNKYG +     +P   E WNGM+ E+I   AD+ +  +T++ ERE  VDFT PFMSLG+ ILF  P KE P LFSF+SP S  VW+++  AY+GVS+ ++ +  ++P EW   +PC ++    +NQF+  N LWF++ AL++QG E  P+A STR V+++WWFFTLI++S+YTANLAAFLTVE +V PI   +DL  N+  + YG   GGA+  FF+ +   TY++M+++M +NP  M  + +EGVD+V  SN  YAFL+ES   +Y  ER CTL +VG +LD KGYGI      P RD +++++L++Q+   L+ +  KWW E      C   ++ S   AL++  +GGVFL++GVG  F   VS++E+ +   E + +  V F      E++F ++   ++K
Sbjct:    5 KMISTEASFPLGFILTSLLLAFPGCRGERTNV----GLVYENTDPDLEKIFHLAISKANEE--NEDLQLHGVSVSIEPGNSFETSKKLCKMLRQNLVAVFGPTSNLAARHAMSICDAKELPFLDTRWDF---GAQLP-TINLHPH-PATLGVALRDMVVALGWESFTIIYESGEYLPTVRELLQMYGTAGPTVTVRRY-ELDLNGNYRNVLRRIRNADDFSFVVVGSMATLPEFFKQAQQVGLVTSDYRYIIGNLDWHTMDLEPYQ-HAGTNITGLRLVSPD--------SEQVQEVAKALYESEEPFQN--VSCPLTNSMALVYDGVQLLAE-TYKHVNFRPV---ALSCNDDSAWDKGYTLVNYMKSL-TLNGLTGPIRFDYEGLRTDFKLEVIELAVSGMQKIGQWSGEDGFQENRPAPAHSLEPDMRS-LVNKSFVVITAISEPYGMLKETSEKLEGNDQ----FEGFGIELIDELSKKLGFSYTWRLQEDNKYGGI-----DPKTGE-WNGMLREIIDSRADMGITDLTMTSERESGVDFTIPFMSLGIGILFRKPMKEPPKLFSFMSPFSGEVWLWLGLAYMGVSISMFVLGRLSPAEWDNPYPCIEEPTELENQFSFANCLWFSIGALLQQGSELAPKAYSTRAVAASWWFFTLILVSSYTANLAAFLTVESLVTPINDADDLSKNKGGVNYGAKIGGATFNFFKESNYPTYQRMYEFMRDNPQYMTNTNQEGVDRVENSN--YAFLMESTTIEYITERRCTLTQVGALLDEKGYGIAMRKNWPYRDTLSQAVLEMQEQGLLTKMKTKWWQEKRGGGACSDADEDSGAVALEISNLGGVFLVMGVGSFFGIFVSLLEMVLGVKERSDENQVSFKTELLDEIRFILQCSGNTK 862          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Fly
Match: Ekar (gene:FBgn0039916 transcript:FBtr0110906)

HSP 1 Score: 401.364 bits (1030), Expect = 3.563e-124
Identity = 263/752 (34.97%), Postives = 418/752 (55.59%), Query Frame = 3
Query:  297 ETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLLNQFEYHFKMRQWIHGD--LKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNEEAQRKQYNLSVMELTENGFMKKGYWNGNNFV-IFPPKSKSPVTETNEVIKPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCD-DNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMEN-NPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTK 2537
            E V+   SF  ++K C L++ G+ A+ +P   + + H++S  +   IP++          +++  +I +YP+     N  F  + Q   W    I+H+ +N I+    L   F     MRQ +  D  +    EF     K ++  + ++D     I   L  +    +    + ++FT +D    DL  FK N  VNIT+F L+ D+    ++   K++     +IF+   L+     +T L + PA++ DS+ V   GL  L +   +    + C    +W+ G+SL N + +V+   GLTG I F ++ QR Q+ L +++L ++  +K G W  +  + I  P   S   +   +   L V TI+  P+V          ++ T  + + GFC+D+L  I  ++  ++ + LV D KYG       +P+  E WNGM+ +L+  +ADL V  MTI+Y RE V+DFT PFM+LG+SILF  P  E   LFSF++PL+  +W+YV+ AY  VSL IY +  ++P EW  I+ CD +N S  NQF++ +S WFT+   M+Q  +  P+A STR++SS W FF+LII+++YTANLAAFLT E+++ PI++ EDL +Q  I YGTL  G++  FF  ++I+TYKK+ + M+N  P     + E+G+ +V  + G YAFL+ES M DY  +R+C L ++G +LD+KGYGI  P GSP RDK++ +IL+LQ+   +  L  KWW   N  E C  K
Sbjct:   66 EYVNRFDSFETVQKVCKLIRVGVQAVFSPTDSVLATHINSICDALDIPNI--------GRSAHDFSINVYPS-KQLVNYAFNDVIQYLNWTRFGILHEKENGIINLHQLSRSFHGEVHMRQ-VSRDSYVSALNEF-----KGKEIHNIIIDTNSNGISILLKNILQQQMNEYKYHYLFTSFDLETYDLEDFKYN-FVNITSFRLV-DTADVGVKQILKDIGLYSHHIFKKPYLNLHIKKSTILESEPALMFDSVYVFAIGLQTLEQSHSLTLLNISCEEENSWDGGLSLINYLNAVEWK-GLTGPIQF-KDGQRVQFKLDLIKLKQHSIVKVGEWTPHGHLNITEP---SMFFDAGSMNVTLVVITILETPYVMMH-----YGKNFTGNERFYGFCVDILETISREVGFDYILDLVPDRKYGA-----KDPETGE-WNGMVAQLMKYKADLAVGSMTITYARESVIDFTKPFMNLGISILFKVPTSEPTRLFSFMNPLAIEIWIYVLIAYFLVSLCIYIVGKLSPIEWKCINACDLENISIGNQFSLTDSFWFTIGTFMQQSPDIYPRAMSTRIISSTWGFFSLIIVASYTANLAAFLTTERMINPIENAEDLASQTEISYGTLDSGSTMTFFRDSVIETYKKIWRSMDNKKPSAFTTTYEDGIKRV--NQGNYAFLMESTMLDYIVQRDCNLTQIGGLLDTKGYGIATPKGSPWRDKISLAILELQERGDIQMLYDKWWK--NTDETCTRK 780          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Zebrafish
Match: grik1a (glutamate receptor, ionotropic, kainate 1a [Source:ZFIN;Acc:ZDB-GENE-030131-6502])

HSP 1 Score: 419.083 bits (1076), Expect = 4.127e-131
Identity = 285/812 (35.10%), Postives = 439/812 (54.06%), Query Frame = 3
Query:  162 LSKIYLTIGVIFEA--NDDVSRKVVS----VAVQNANSQLMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLL---NQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLIN--DSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNE-EAQRKQYNLSVMELTENGFMKKGYWNG-NNFVIFPPKSKSPVTETNEVIKPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCDDNGSR-QNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNPD-VMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKGSI 2552
            +S+I+L  G IFE   N+ VS   ++    V   N N  LM  N +     + V+   SF   R+ C+ L  G+ A+  P        + S  N   +PH+ T+ + P         I LYP   + +  I   I     W  + ++++    +M+ + L+   ++     ++RQ   G    +   L K  K  K  + + D  Y    + L  + +  +    + F FT  D   LDL  ++ +  VN+TAF L+N  DS V S+  +       ME      K  +   ++  +  A A++ D++ ++     R  ++       ++C  +  W  G    N         GLTGRIV N+ +  RK++NL ++ L E+G  K G WN      +   K    +T++    + L VTTI+  P+V YK +   +  +D     + G+C+DLL E+   L   + + LV D KYG   D         +WNGM+ ELI   ADL VAP+TI+Y REKV+DF+ PFM+LG+SIL+  P    PG+FSFL+PL+P +W+YV+ A +GVS +++ I+  TPYEW   HPC+ +    +N F +LNSLWF VAALMRQG E  P+A STR++   WWFFTLIIIS+YTANLAAFLTVE++  PI S +DL  Q  I+YG ++ G++  FF+++ I TY+KM  +M +  +  +V+++++G+ +VL ++  YA L+ES   +Y  +R C L +VG ++DSKGYG+G P GSP RDK+T +IL+LQ+  KL  +  KWW      E  D+KE  ++
Sbjct:   14 VSEIHLCAGGIFETRENEPVSMDELAFKFAVTSINRNRTLMP-NTTLTYDIQRVNLFDSFEASRRVCDQLALGVAAVFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDNFYINLYPEYTSISRAILD-IVIFYKWKCVTVVYEDSTGLMRMQELIKAPSKNNLKIRIRQLPSGG--GDSRPLLKEMKKEKEFYVIFDCSYQVAAELLKQLMSMGMMTEYYHFFFTTLDLFALDLEPYRYSG-VNMTAFRLLNLDDSYVASVIQKWS-----MERQLAPPK-PESGLMSGIMTTAAALMYDAVFMVAVASQRATQMT---VSSLQCHRHKPWRYGPRFMNLFKEA-QWDGLTGRIVLNKTDGLRKEFNLDLISLKEDGTAKIGVWNSYTGLNLTEIKDNKNITDS-LANRTLIVTTILENPYVMYKKSDKVLYGNDR----FEGYCLDLLKELSNILGFTYEVKLVTDGKYGAQNDKG-------EWNGMVRELIDHIADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLTPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPSSEVVENNFTLLNSLWFGVAALMRQGSELMPKALSTRILGGIWWFFTLIIISSYTANLAAFLTVERMDSPIDSADDLAKQTRIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRKNTALVKNSKDGITRVLTTD--YALLMESTSIEYITQRNCNLTQVGGLIDSKGYGVGTPIGSPYRDKVTIAILQLQEEGKLHMMKEKWWRGNGCPEE-DSKEASAL 795          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Zebrafish
Match: grik1a (glutamate receptor, ionotropic, kainate 1a [Source:ZFIN;Acc:ZDB-GENE-030131-6502])

HSP 1 Score: 416.772 bits (1070), Expect = 8.465e-130
Identity = 284/819 (34.68%), Postives = 440/819 (53.72%), Query Frame = 3
Query:  162 LSKIYLT------IGVIFEAN-------DDVSRKVVSVAVQNANSQLMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLL---NQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLIN--DSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNE-EAQRKQYNLSVMELTENGFMKKGYWNG-NNFVIFPPKSKSPVTETNEVIKPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCDDNGSR-QNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNPD-VMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKGSI 2552
            ++K YL+      IG IFE         D+++ K    ++ N N  LM  N +     + V+   SF   R+ C+ L  G+ A+  P        + S  N   +PH+ T+ + P         I LYP   + +  I   I     W  + ++++    +M+ + L+   ++     ++RQ   G    +   L K  K  K  + + D  Y    + L  + +  +    + F FT  D   LDL  ++ +  VN+TAF L+N  DS V S+  +       ME      K  +   ++  +  A A++ D++ ++     R  ++       ++C  +  W  G    N         GLTGRIV N+ +  RK++NL ++ L E+G  K G WN      +   K    +T++    + L VTTI+  P+V YK +   +  +D     + G+C+DLL E+   L   + + LV D KYG   D         +WNGM+ ELI   ADL VAP+TI+Y REKV+DF+ PFM+LG+SIL+  P    PG+FSFL+PL+P +W+YV+ A +GVS +++ I+  TPYEW   HPC+ +    +N F +LNSLWF VAALMRQG E  P+A STR++   WWFFTLIIIS+YTANLAAFLTVE++  PI S +DL  Q  I+YG ++ G++  FF+++ I TY+KM  +M +  +  +V+++++G+ +VL ++  YA L+ES   +Y  +R C L +VG ++DSKGYG+G P GSP RDK+T +IL+LQ+  KL  +  KWW      E  D+KE  ++
Sbjct:   28 MAKFYLSEQQVIRIGGIFETRENEPVSMDELAFKFAVTSI-NRNRTLMP-NTTLTYDIQRVNLFDSFEASRRVCDQLALGVAAVFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDNFYINLYPEYTSISRAILD-IVIFYKWKCVTVVYEDSTGLMRMQELIKAPSKNNLKIRIRQLPSGG--GDSRPLLKEMKKEKEFYVIFDCSYQVAAELLKQLMSMGMMTEYYHFFFTTLDLFALDLEPYRYSG-VNMTAFRLLNLDDSYVASVIQKWS-----MERQLAPPK-PESGLMSGIMTTAAALMYDAVFMVAVASQRATQMT---VSSLQCHRHKPWRYGPRFMNLFKEA-QWDGLTGRIVLNKTDGLRKEFNLDLISLKEDGTAKIGVWNSYTGLNLTEIKDNKNITDS-LANRTLIVTTILENPYVMYKKSDKVLYGNDR----FEGYCLDLLKELSNILGFTYEVKLVTDGKYGAQNDKG-------EWNGMVRELIDHIADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLTPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPSSEVVENNFTLLNSLWFGVAALMRQGSELMPKALSTRILGGIWWFFTLIIISSYTANLAAFLTVERMDSPIDSADDLAKQTRIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRKNTALVKNSKDGITRVLTTD--YALLMESTSIEYITQRNCNLTQVGGLIDSKGYGVGTPIGSPYRDKVTIAILQLQEEGKLHMMKEKWWRGNGCPEE-DSKEASAL 815          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Zebrafish
Match: GRIK2 (glutamate receptor, ionotropic, kainate 2 [Source:NCBI gene;Acc:556013])

HSP 1 Score: 413.305 bits (1061), Expect = 1.768e-128
Identity = 268/795 (33.71%), Postives = 433/795 (54.47%), Query Frame = 3
Query:  177 LTIGVIFEANDDVSRKVVSVAVQ------NANSQLMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLL---NQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAA-----PAIIIDSINVLMEGLIRLIKLQPVFT-QPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNE-EAQRKQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKSPVTETNEVI--KPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCD-DNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNP-DVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWW 2501
            L  G IFE+ +        +A +      N N  L+  N +     + ++ + SF   RKAC+ L  G+ A+  P     +  + S  N   +PH+ TK +   S       + LYP+  + +  I   +     W  + +++     +++ + L+   +++    K+RQ +  D K  K  L+++ + ++  H + D  +      L       +    + +IFT  D   LD+  ++ +  VN+T F ++N        T +  ++S++E  +   +L      ++ LL        A++ D+++V+       ++  P  T   ++C  +  W  G + F  +    H  GLTGRI FN     R  ++L V+ L E G  K G W+  + +      K       + +  + L V+TI+  P+V +K +   +  +D     + G+C+DLL E+ A L   + + LV+D +YG         + S +WNGM+ EL+  +ADL VAP+ I+Y REKV+DF+ PFM+LG+SIL+  P    PG+FSFL+PLSP +W+Y++ AY+GVS +++ I+  +PYEW   HPC+ D+   +N F +LNS WF V ALM+QG E  P+A STR+V   WWFFTLIIIS+YTANLAAFLTVE++  PI S +DL  Q  I+YG ++ G++  FF++  I TY KM ++M +    VMV+S EEG+++VL S+  YAFL+ES   ++  +R C L ++G ++DSK YG+G P GSP RDK+T +IL+LQ+  KL  +  KWW
Sbjct:   36 LRFGGIFESIESGPSGAEELAFKFALNTINRNRTLLP-NTTLTYDIQRINIHDSFEASRKACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTKWKHQVSDNRDSFYVNLYPDFSSLSRAILDLV-HFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNIRLKIRQ-LPADTKDAKPLLKEMKRGKEF-HVIFDCGHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYSG-VNMTGFRILN--------TENSQVSSIIEK-WSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVAV----AVQQSPQITVSSLQCNRHKPWRFG-NRFMTLIKEAHWDGLTGRINFNRTNGLRTDFDLDVISLKEEGLEKIGTWDPASGLNMTENQKGKTANVTDSLSNRSLVVSTILEEPYVMFKKSDKPLYGNDR----FEGYCVDLLRELAAILGFGYELRLVEDGRYGA------QDESSGQWNGMVRELMDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGVVEDGSTMTFFKKTKISTYDKMWEFMSSRRHSVMVKSIEEGIERVLTSD--YAFLMESTTIEFVTQRNCNLTQIGGLIDSKAYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKWW 799          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Zebrafish
Match: GRIK2 (glutamate receptor, ionotropic, kainate 2 [Source:NCBI gene;Acc:556013])

HSP 1 Score: 413.305 bits (1061), Expect = 1.768e-128
Identity = 268/795 (33.71%), Postives = 433/795 (54.47%), Query Frame = 3
Query:  177 LTIGVIFEANDDVSRKVVSVAVQ------NANSQLMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLL---NQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAA-----PAIIIDSINVLMEGLIRLIKLQPVFT-QPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNE-EAQRKQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKSPVTETNEVI--KPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCD-DNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNP-DVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWW 2501
            L  G IFE+ +        +A +      N N  L+  N +     + ++ + SF   RKAC+ L  G+ A+  P     +  + S  N   +PH+ TK +   S       + LYP+  + +  I   +     W  + +++     +++ + L+   +++    K+RQ +  D K  K  L+++ + ++  H + D  +      L       +    + +IFT  D   LD+  ++ +  VN+T F ++N        T +  ++S++E  +   +L      ++ LL        A++ D+++V+       ++  P  T   ++C  +  W  G + F  +    H  GLTGRI FN     R  ++L V+ L E G  K G W+  + +      K       + +  + L V+TI+  P+V +K +   +  +D     + G+C+DLL E+ A L   + + LV+D +YG         + S +WNGM+ EL+  +ADL VAP+ I+Y REKV+DF+ PFM+LG+SIL+  P    PG+FSFL+PLSP +W+Y++ AY+GVS +++ I+  +PYEW   HPC+ D+   +N F +LNS WF V ALM+QG E  P+A STR+V   WWFFTLIIIS+YTANLAAFLTVE++  PI S +DL  Q  I+YG ++ G++  FF++  I TY KM ++M +    VMV+S EEG+++VL S+  YAFL+ES   ++  +R C L ++G ++DSK YG+G P GSP RDK+T +IL+LQ+  KL  +  KWW
Sbjct:   36 LRFGGIFESIESGPSGAEELAFKFALNTINRNRTLLP-NTTLTYDIQRINIHDSFEASRKACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTKWKHQVSDNRDSFYVNLYPDFSSLSRAILDLV-HFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNIRLKIRQ-LPADTKDAKPLLKEMKRGKEF-HVIFDCGHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYSG-VNMTGFRILN--------TENSQVSSIIEK-WSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVAV----AVQQSPQITVSSLQCNRHKPWRFG-NRFMTLIKEAHWDGLTGRINFNRTNGLRTDFDLDVISLKEEGLEKIGTWDPASGLNMTENQKGKTANVTDSLSNRSLVVSTILEEPYVMFKKSDKPLYGNDR----FEGYCVDLLRELAAILGFGYELRLVEDGRYGA------QDESSGQWNGMVRELMDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGVVEDGSTMTFFKKTKISTYDKMWEFMSSRRHSVMVKSIEEGIERVLTSD--YAFLMESTTIEFVTQRNCNLTQIGGLIDSKAYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKWW 799          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Zebrafish
Match: grik1b (glutamate receptor, ionotropic, kainate 1b [Source:ZFIN;Acc:ZDB-GENE-070821-1])

HSP 1 Score: 412.149 bits (1058), Expect = 2.855e-128
Identity = 285/840 (33.93%), Postives = 453/840 (53.93%), Query Frame = 3
Query:  123 LLMLLGRPILSKELSKIYLTIGVIFEA--NDDVSRKVVSV--AVQNAN-SQLMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLL---NQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLV--DLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLIN--DSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNE-EAQRKQYNLSVMELTENGFMKK-------------GYWNGNNFVIFPPKSKSPVTETNEVI--KPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCD-DNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNPD-VMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKGSI 2552
            LL L+    LS   ++  L IG IFE   N+ +S + ++   AV N N ++ +  N +     + ++   SF   R+AC+ L  G+ A+  P        + S  N   +PH+ T+ + P         I LYP+  + +  +   I Q   W  + ++++    +++ + L+   +++    K+RQ   G  K  +  L+++   +K K F V  D  Y    D L  + +  +    + F FT  D   LDL  F+ +  VN+T F L+N  +  V S+  +       ME +    K  +    +  +    A++ D++ ++     R  ++       ++C  +  W  G S F ++       GLTG+I+ N+ +  RK ++L ++ L E+G  K              G WN N  +     +K   T   + +  + L VTTI+  P+V YK +   +  +D     + G+C+DLL E+   L  ++ + LV D KYG   D         +WNGM+ ELI   ADL VAP+TI+Y REKV+DF+ PFM+LG+SIL+  P    PG+FSFL+PLSP +W+YV+ A +GVS +++ I+  TPYEW   HPC+ D+   +N F ++NS+WF V ALM+QG E  P+A STR+V   WWFFTLIIIS+YTANLAAFLTVE++  PI S +DL  Q  I+YG ++ G++  FF+++ I TY+KM  +M +  +  +V++  EG+ +VL ++  YA L+ES   +Y  +R C L ++G ++DSKGYG+G P GSP RDK+T +IL+LQ+  KL  +  KWW      E  D+KE  ++
Sbjct:   22 LLCLMAEVGLS---AQQVLRIGGIFETLENEPISVEELAFKFAVTNINRNRTLMPNTTLTYDIQRINLFDSFEASRRACDQLALGVAAVFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDSFYINLYPDYASISRAVLD-IVQFYKWKAVTVVYEDATGLIRLQELIKAPSRYSIKIKIRQLPTGS-KDARPLLKEM---KKGKEFCVIFDCSYQTAADVLKQLLSMGMMTEYYHFFFTTLDLYSLDLEPFRYSG-VNMTGFRLLNIDNPQVASVVEKWS-----MERLQAPPK-PETGLQDGMMTTEAALMYDAVYMVAAASQRASQIT---VSSLQCHRHKPWRFG-SRFISMFKEAQWNGLTGQIIINKTDGLRKDFDLDIISLKEDGLEKPLESGRFNKVWKKIGVWNSNTGLNLTDSNKDKNTNVTDSMANRTLIVTTILENPYVMYKKSDKPLYGNDR----FEGYCLDLLKELSNILGFSYEVKLVTDGKYGAQNDKG-------EWNGMVRELIDHVADLAVAPLTITYVREKVIDFSKPFMTLGISILYHKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTLINSVWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMDSPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRKNTALVKNNREGIQRVLTTD--YALLMESTSIEYISQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKVTIAILQLQEEGKLHMMKEKWWRGNGCPEE-DSKEASAL 828          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Xenopus
Match: GRIK4 (glutamate receptor, ionotropic, kainate 4 [Source:NCBI gene;Acc:100490768])

HSP 1 Score: 417.542 bits (1072), Expect = 1.629e-133
Identity = 224/510 (43.92%), Postives = 326/510 (63.92%), Query Frame = 3
Query: 1026 APAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNEEAQRKQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKSPVTETNEVIKPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCDDNGSRQ--NQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMEN-NPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKG 2546
            + A++ D++  ++  +  L + Q +  +P+ C ++  W  G SL N +  V+ + GLTG + FN + QR  Y++ +M+ T+ GF + G W+  N +    +  S       V K L VTTI+  P++  K N  +++ +D     + GFC+D+L E+ A LR N+ I LV D  YG        P+ +  W GM+GELIS++ADL VA +TI+ EREKV+DF+ PFM+LG+SIL+       PG FSFL P SP VW++++ AY+ VS +++ ++ +TPYEW   HPC         NQ+++ NSLWF V   M+QG    P+A STR VS  WW FTLIIIS+YTANLAAFLTV+++ +PI+SV+DL +Q TI+YGT+ GG+S  FF+ +  QTY++M  YM +  P V V+STEEG+ +VL SN  YAFLLES MN+YY++R C L +VG +LD+KGYGIG P GS  RD+   +IL+LQ++  L +L  KWW+     +  D + KG
Sbjct:   12 SAALLFDAVYGIVSAVQELNRSQEIGVKPLSCGSSQIWQHGTSLMNYLRMVE-LEGLTGHVEFNSKGQRSNYDMKIMQYTKTGFQEIGQWHVTNGLNMDKRYFSKNASDTLVNKTLIVTTILENPYLMLKANHQELEGNDR----YEGFCVDMLKELAAILRFNYKIRLVADGVYGV-------PELNGTWTGMVGELISRKADLAVAGLTITAEREKVIDFSKPFMTLGISILYRVHMGRKPGYFSFLDPFSPGVWLFMLLAYLAVSCVLFLVARLTPYEWYSPHPCAQGRCNLLVNQYSLGNSLWFPVGGFMQQGSTIAPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMDVPIESVDDLADQTTIEYGTIHGGSSMTFFQNSRYQTYQRMWNYMHSKQPSVFVKSTEEGIARVLNSN--YAFLLESTMNEYYRQRNCNLTQVGGLLDTKGYGIGMPVGSAFRDEFDLAILQLQENNCLEDLKRKWWDGGKCPKEEDHRAKG 507          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Xenopus
Match: GRIK1 (glutamate receptor, ionotropic, kainate 1 [Source:NCBI gene;Acc:100493949])

HSP 1 Score: 424.861 bits (1091), Expect = 5.043e-133
Identity = 276/828 (33.33%), Postives = 450/828 (54.35%), Query Frame = 3
Query:  114 FPFLLMLLGRPILSKELSKIYLTIGVIFEANDD----VSRKVVSVAVQNAN-SQLMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLL---NQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLIN--DSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNE-EAQRKQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKSPVTETNEVI--KPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCD-DNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNPD-VMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKGSI 2552
             PFL  L     ++ + S+  L IG IFE  ++    V       AV N N ++ +  N +     + ++   SF   R+AC+ L  G+ AL  P        + S  N   +PH+ T+ + P         I L+P+  A +  + + +    +W  + ++++    +++ + L+   +++    K+RQ   G+ K  +  L+++ KSR+  + + D  +    + L  + +  +    + + FT  D   LDL  ++ +  VN+T F L+N  +  V+S+  +       ME +    K  +   ++  +    A++ D++ ++     R  ++       ++C  +  W  G    + I       GLTGRI FN  +  R+ +++ ++ L E+G  K G WN N  +      K   T   + +  + L VTTI+  P+V ++ +   +  +D     + G+C+DLL E+   L   + + LV D KYG   D         +WNGM+ ELI  +ADL VAP+TI+Y REKV+DF+ PFM+LG+SIL+  P    PG+FSFL+PLSP +W+YV+ A +GVS +++ I+  TPYEW   HPC+ D+   +N F +LNS WF V ALM+QG E  P+A STR+V   WWFFTLIIIS+YTANLAAFLTVE++  PI S +DL  Q  I+YG ++ G++  FF+++ I TY+KM  +M +     +V++ +EG+ +VL ++  YA L+ES   +Y  +R C L ++G ++DSKGYG+G P GSP RDK+T +IL+LQ+  KL  +  KWW      E  D+KE  ++
Sbjct:    9 LPFLCALAA---ITPQASQQVLRIGGIFETVENEPINVEELAFKFAVTNINRNRTLMPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDSFFINLHPDYAAISRAVLELVLHY-SWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGN-KDARTLLKEMKKSREF-YVIFDCSHETAAEILKQILSMGMMTEYYHYFFTTMDLFALDLEPYRYSG-VNMTGFRLLNIDNPQVSSVVEKWS-----MERLQAPPK-PETGLLDGMMTTDAALMYDAVYMVAVATQRATQMT---VSSLQCHRHKPWRFGPRFMSLIKEA-RWDGLTGRITFNRTDGLRRDFDMDIISLKEDGMEKVGVWNSNTGLNMTDNLKDKSTNITDSLANRTLIVTTILEDPYVMFRKSDKPLYGNDR----FEGYCLDLLKELSNILGFTYEVRLVVDGKYGAQNDKG-------EWNGMVRELIDHKADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQTALVKNNDEGIQRVLTTD--YALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEE-DSKEASAL 805          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Xenopus
Match: GRIK4 (glutamate receptor, ionotropic, kainate 4 [Source:NCBI gene;Acc:100490768])

HSP 1 Score: 425.631 bits (1093), Expect = 1.090e-132
Identity = 243/582 (41.75%), Postives = 355/582 (61.00%), Query Frame = 3
Query:  810 HSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNEEAQRKQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKSPVTETNEVIKPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCDDNGSRQ--NQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMEN-NPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKG 2546
            +++IFT+ +  +L      ++++VNI  FS+ N S        H    S  EN   S       F    L AA  ++ D++  ++  +  L + Q +  +P+ C ++  W  G SL N +  V+ + GLTG + FN + QR  Y++ +M+ T+ GF + G W+  N +    +  S       V K L VTTI+  P++  K N  +++ +D     + GFC+D+L E+ A LR N+ I LV D  YG        P+ +  W GM+GELIS++ADL VA +TI+ EREKV+DF+ PFM+LG+SIL+       PG FSFL P SP VW++++ AY+ VS +++ ++ +TPYEW   HPC         NQ+++ NSLWF V   M+QG    P+A STR VS  WW FTLIIIS+YTANLAAFLTV+++ +PI+SV+DL +Q TI+YGT+ GG+S  FF+ +  QTY++M  YM +  P V V+STEEG+ +VL SN  YAFLLES MN+YY++R C L +VG +LD+KGYGIG P GS  RD+   +IL+LQ++  L +L  KWW+     +  D + KG
Sbjct:  206 YTYIFTNLEF-VLQRFESPLDDRVNILGFSMFNQSHSYFKEFAHTLQQSWEENCDHS------PFTGPALSAA--LLFDAVYGIVSAVQELNRSQEIGVKPLSCGSSQIWQHGTSLMNYLRMVE-LEGLTGHVEFNSKGQRSNYDMKIMQYTKTGFQEIGQWHVTNGLNMDKRYFSKNASDTLVNKTLIVTTILENPYLMLKANHQELEGNDR----YEGFCVDMLKELAAILRFNYKIRLVADGVYGV-------PELNGTWTGMVGELISRKADLAVAGLTITAEREKVIDFSKPFMTLGISILYRVHMGRKPGYFSFLDPFSPGVWLFMLLAYLAVSCVLFLVARLTPYEWYSPHPCAQGRCNLLVNQYSLGNSLWFPVGGFMQQGSTIAPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMDVPIESVDDLADQTTIEYGTIHGGSSMTFFQNSRYQTYQRMWNYMHSKQPSVFVKSTEEGIARVLNSN--YAFLLESTMNEYYRQRNCNLTQVGGLLDTKGYGIGMPVGSAFRDEFDLAILQLQENNCLEDLKRKWWDGGKCPKEEDHRAKG 764          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Xenopus
Match: GRIK4 (glutamate receptor, ionotropic, kainate 4 [Source:NCBI gene;Acc:100490768])

HSP 1 Score: 424.091 bits (1089), Expect = 1.133e-132
Identity = 239/563 (42.45%), Postives = 345/563 (61.28%), Query Frame = 3
Query:  867 INNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNEEAQRKQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKSPVTETNEVIKPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCDDNGSRQ--NQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMEN-NPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKG 2546
            ++++VNI  FS+ N S        H    S  EN   S       F    L AA  ++ D++  ++  +  L + Q +  +P+ C ++  W  G SL N +  V+ + GLTG + FN + QR  Y++ +M+ T+ GF + G W+  N +    +  S       V K L VTTI+  P++  K N  +++ +D     + GFC+D+L E+ A LR N+ I LV D  YG        P+ +  W GM+GELIS++ADL VA +TI+ EREKV+DF+ PFM+LG+SIL+       PG FSFL P SP VW++++ AY+ VS +++ ++ +TPYEW   HPC         NQ+++ NSLWF V   M+QG    P+A STR VS  WW FTLIIIS+YTANLAAFLTV+++ +PI+SV+DL +Q TI+YGT+ GG+S  FF+ +  QTY++M  YM +  P V V+STEEG+ +VL SN  YAFLLES MN+YY++R C L +VG +LD+KGYGIG P GS  RD+   +IL+LQ++  L +L  KWW+     +  D + KG
Sbjct:  240 LDDRVNILGFSMFNQSHSYFKEFAHTLQQSWEENCDHS------PFTGPALSAA--LLFDAVYGIVSAVQELNRSQEIGVKPLSCGSSQIWQHGTSLMNYLRMVE-LEGLTGHVEFNSKGQRSNYDMKIMQYTKTGFQEIGQWHVTNGLNMDKRYFSKNASDTLVNKTLIVTTILENPYLMLKANHQELEGNDR----YEGFCVDMLKELAAILRFNYKIRLVADGVYGV-------PELNGTWTGMVGELISRKADLAVAGLTITAEREKVIDFSKPFMTLGISILYRVHMGRKPGYFSFLDPFSPGVWLFMLLAYLAVSCVLFLVARLTPYEWYSPHPCAQGRCNLLVNQYSLGNSLWFPVGGFMQQGSTIAPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMDVPIESVDDLADQTTIEYGTIHGGSSMTFFQNSRYQTYQRMWNYMHSKQPSVFVKSTEEGIARVLNSN--YAFLLESTMNEYYRQRNCNLTQVGGLLDTKGYGIGMPVGSAFRDEFDLAILQLQENNCLEDLKRKWWDGGKCPKEEDHRAKG 780          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Xenopus
Match: GRIK4 (glutamate receptor, ionotropic, kainate 4 [Source:NCBI gene;Acc:100490768])

HSP 1 Score: 423.705 bits (1088), Expect = 1.288e-132
Identity = 239/563 (42.45%), Postives = 345/563 (61.28%), Query Frame = 3
Query:  867 INNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNEEAQRKQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKSPVTETNEVIKPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCDDNGSRQ--NQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMEN-NPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKG 2546
            ++++VNI  FS+ N S        H    S  EN   S       F    L AA  ++ D++  ++  +  L + Q +  +P+ C ++  W  G SL N +  V+ + GLTG + FN + QR  Y++ +M+ T+ GF + G W+  N +    +  S       V K L VTTI+  P++  K N  +++ +D     + GFC+D+L E+ A LR N+ I LV D  YG        P+ +  W GM+GELIS++ADL VA +TI+ EREKV+DF+ PFM+LG+SIL+       PG FSFL P SP VW++++ AY+ VS +++ ++ +TPYEW   HPC         NQ+++ NSLWF V   M+QG    P+A STR VS  WW FTLIIIS+YTANLAAFLTV+++ +PI+SV+DL +Q TI+YGT+ GG+S  FF+ +  QTY++M  YM +  P V V+STEEG+ +VL SN  YAFLLES MN+YY++R C L +VG +LD+KGYGIG P GS  RD+   +IL+LQ++  L +L  KWW+     +  D + KG
Sbjct:  240 LDDRVNILGFSMFNQSHSYFKEFAHTLQQSWEENCDHS------PFTGPALSAA--LLFDAVYGIVSAVQELNRSQEIGVKPLSCGSSQIWQHGTSLMNYLRMVE-LEGLTGHVEFNSKGQRSNYDMKIMQYTKTGFQEIGQWHVTNGLNMDKRYFSKNASDTLVNKTLIVTTILENPYLMLKANHQELEGNDR----YEGFCVDMLKELAAILRFNYKIRLVADGVYGV-------PELNGTWTGMVGELISRKADLAVAGLTITAEREKVIDFSKPFMTLGISILYRVHMGRKPGYFSFLDPFSPGVWLFMLLAYLAVSCVLFLVARLTPYEWYSPHPCAQGRCNLLVNQYSLGNSLWFPVGGFMQQGSTIAPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMDVPIESVDDLADQTTIEYGTIHGGSSMTFFQNSRYQTYQRMWNYMHSKQPSVFVKSTEEGIARVLNSN--YAFLLESTMNEYYRQRNCNLTQVGGLLDTKGYGIGMPVGSAFRDEFDLAILQLQENNCLEDLKRKWWDGGKCPKEEDHRAKG 780          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Mouse
Match: Grik2 (glutamate receptor, ionotropic, kainate 2 (beta 2) [Source:MGI Symbol;Acc:MGI:95815])

HSP 1 Score: 427.557 bits (1098), Expect = 5.358e-134
Identity = 273/787 (34.69%), Postives = 434/787 (55.15%), Query Frame = 3
Query:  231 SVAVQNANSQLMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLL---NQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAA-----PAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNE-EAQRKQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKS-PVTETNEVI-KPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCD-DNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMEN-NPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKGSI 2552
            +V   N N  L+  N +    T+ ++   SF   +KAC+ L  G+ A+  P     +  + S  N   +PH+ T+ +   S       + LYP+  + +  I   + Q   W  + +++     +++ + L+   +++    K+RQ +  D K  K  L+++ K  K  H + D  +      L       +    + +IFT  D   LD+  ++ +  VN+T F ++N        T +  ++S++E  +   +L      ++ LL        A++ D+++V+    + + +   +    ++C  +  W  G    + I    H  GLTGRI FN+    R  ++L V+ L E G  K G W+ ++ +      K  P   T+ +  + L VTTI+  P+V +K +   +  +D     + G+CIDLL E+   L   + I LV+D KYG         D + +WNGM+ ELI  +ADL VAP+ I+Y REKV+DF+ PFM+LG+SIL+  P    PG+FSFL+PLSP +W+Y++ AY+GVS +++ I+  +PYEW   HPC+ D+   +N F +LNS WF V ALM+QG E  P+A STR+V   WWFFTLIIIS+YTANLAAFLTVE++  PI S +DL  Q  I+YG ++ GA+  FF+++ I TY KM  +M +    V+V+S EEG+ +VL S+  YAFL+ES   ++  +R C L ++G ++DSKGYG+G P GSP RDK+T +IL+LQ+  KL  +  KWW      E  ++KE  ++
Sbjct:   60 AVNTINRNRTLLP-NTTLTYDTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDFSSLSRAILDLV-QFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQ-LPADTKDAKPLLKEM-KRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYSG-VNMTGFRILN--------TENTQVSSIIEK-WSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVS---VAVQQFPQMTVSSLQCNRHKPWRFGTRFMSLIKEA-HWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPSSGLNMTESQKGKPANITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDR----FEGYCIDLLRELSTILGFTYEIRLVEDGKYGA------QDDVNGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGIQRVLTSD--YAFLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEE-ESKEASAL 815          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Mouse
Match: Grik2 (glutamate receptor, ionotropic, kainate 2 (beta 2) [Source:MGI Symbol;Acc:MGI:95815])

HSP 1 Score: 426.787 bits (1096), Expect = 6.068e-134
Identity = 273/787 (34.69%), Postives = 434/787 (55.15%), Query Frame = 3
Query:  231 SVAVQNANSQLMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLL---NQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAA-----PAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNE-EAQRKQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKS-PVTETNEVI-KPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCD-DNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMEN-NPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKGSI 2552
            +V   N N  L+  N +    T+ ++   SF   +KAC+ L  G+ A+  P     +  + S  N   +PH+ T+ +   S       + LYP+  + +  I   + Q   W  + +++     +++ + L+   +++    K+RQ +  D K  K  L+++ K  K  H + D  +      L       +    + +IFT  D   LD+  ++ +  VN+T F ++N        T +  ++S++E  +   +L      ++ LL        A++ D+++V+    + + +   +    ++C  +  W  G    + I    H  GLTGRI FN+    R  ++L V+ L E G  K G W+ ++ +      K  P   T+ +  + L VTTI+  P+V +K +   +  +D     + G+CIDLL E+   L   + I LV+D KYG         D + +WNGM+ ELI  +ADL VAP+ I+Y REKV+DF+ PFM+LG+SIL+  P    PG+FSFL+PLSP +W+Y++ AY+GVS +++ I+  +PYEW   HPC+ D+   +N F +LNS WF V ALM+QG E  P+A STR+V   WWFFTLIIIS+YTANLAAFLTVE++  PI S +DL  Q  I+YG ++ GA+  FF+++ I TY KM  +M +    V+V+S EEG+ +VL S+  YAFL+ES   ++  +R C L ++G ++DSKGYG+G P GSP RDK+T +IL+LQ+  KL  +  KWW      E  ++KE  ++
Sbjct:   60 AVNTINRNRTLLP-NTTLTYDTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDFSSLSRAILDLV-QFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQ-LPADTKDAKPLLKEM-KRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYSG-VNMTGFRILN--------TENTQVSSIIEK-WSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVS---VAVQQFPQMTVSSLQCNRHKPWRFGTRFMSLIKEA-HWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPSSGLNMTESQKGKPANITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDR----FEGYCIDLLRELSTILGFTYEIRLVEDGKYGA------QDDVNGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGIQRVLTSD--YAFLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEE-ESKEASAL 815          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Mouse
Match: Grik2 (glutamate receptor, ionotropic, kainate 2 (beta 2) [Source:MGI Symbol;Acc:MGI:95815])

HSP 1 Score: 426.787 bits (1096), Expect = 6.068e-134
Identity = 273/787 (34.69%), Postives = 434/787 (55.15%), Query Frame = 3
Query:  231 SVAVQNANSQLMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLL---NQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAA-----PAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNE-EAQRKQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKS-PVTETNEVI-KPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCD-DNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMEN-NPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKGSI 2552
            +V   N N  L+  N +    T+ ++   SF   +KAC+ L  G+ A+  P     +  + S  N   +PH+ T+ +   S       + LYP+  + +  I   + Q   W  + +++     +++ + L+   +++    K+RQ +  D K  K  L+++ K  K  H + D  +      L       +    + +IFT  D   LD+  ++ +  VN+T F ++N        T +  ++S++E  +   +L      ++ LL        A++ D+++V+    + + +   +    ++C  +  W  G    + I    H  GLTGRI FN+    R  ++L V+ L E G  K G W+ ++ +      K  P   T+ +  + L VTTI+  P+V +K +   +  +D     + G+CIDLL E+   L   + I LV+D KYG         D + +WNGM+ ELI  +ADL VAP+ I+Y REKV+DF+ PFM+LG+SIL+  P    PG+FSFL+PLSP +W+Y++ AY+GVS +++ I+  +PYEW   HPC+ D+   +N F +LNS WF V ALM+QG E  P+A STR+V   WWFFTLIIIS+YTANLAAFLTVE++  PI S +DL  Q  I+YG ++ GA+  FF+++ I TY KM  +M +    V+V+S EEG+ +VL S+  YAFL+ES   ++  +R C L ++G ++DSKGYG+G P GSP RDK+T +IL+LQ+  KL  +  KWW      E  ++KE  ++
Sbjct:   60 AVNTINRNRTLLP-NTTLTYDTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDFSSLSRAILDLV-QFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQ-LPADTKDAKPLLKEM-KRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYSG-VNMTGFRILN--------TENTQVSSIIEK-WSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVS---VAVQQFPQMTVSSLQCNRHKPWRFGTRFMSLIKEA-HWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPSSGLNMTESQKGKPANITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDR----FEGYCIDLLRELSTILGFTYEIRLVEDGKYGA------QDDVNGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGIQRVLTSD--YAFLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEE-ESKEASAL 815          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Mouse
Match: Grik2 (glutamate receptor, ionotropic, kainate 2 (beta 2) [Source:MGI Symbol;Acc:MGI:95815])

HSP 1 Score: 427.557 bits (1098), Expect = 9.412e-134
Identity = 273/787 (34.69%), Postives = 434/787 (55.15%), Query Frame = 3
Query:  231 SVAVQNANSQLMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLL---NQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAA-----PAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNE-EAQRKQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKS-PVTETNEVI-KPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCD-DNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMEN-NPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKGSI 2552
            +V   N N  L+  N +    T+ ++   SF   +KAC+ L  G+ A+  P     +  + S  N   +PH+ T+ +   S       + LYP+  + +  I   + Q   W  + +++     +++ + L+   +++    K+RQ +  D K  K  L+++ K  K  H + D  +      L       +    + +IFT  D   LD+  ++ +  VN+T F ++N        T +  ++S++E  +   +L      ++ LL        A++ D+++V+    + + +   +    ++C  +  W  G    + I    H  GLTGRI FN+    R  ++L V+ L E G  K G W+ ++ +      K  P   T+ +  + L VTTI+  P+V +K +   +  +D     + G+CIDLL E+   L   + I LV+D KYG         D + +WNGM+ ELI  +ADL VAP+ I+Y REKV+DF+ PFM+LG+SIL+  P    PG+FSFL+PLSP +W+Y++ AY+GVS +++ I+  +PYEW   HPC+ D+   +N F +LNS WF V ALM+QG E  P+A STR+V   WWFFTLIIIS+YTANLAAFLTVE++  PI S +DL  Q  I+YG ++ GA+  FF+++ I TY KM  +M +    V+V+S EEG+ +VL S+  YAFL+ES   ++  +R C L ++G ++DSKGYG+G P GSP RDK+T +IL+LQ+  KL  +  KWW      E  ++KE  ++
Sbjct:   60 AVNTINRNRTLLP-NTTLTYDTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDFSSLSRAILDLV-QFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQ-LPADTKDAKPLLKEM-KRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYSG-VNMTGFRILN--------TENTQVSSIIEK-WSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVS---VAVQQFPQMTVSSLQCNRHKPWRFGTRFMSLIKEA-HWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPSSGLNMTESQKGKPANITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDR----FEGYCIDLLRELSTILGFTYEIRLVEDGKYGA------QDDVNGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGIQRVLTSD--YAFLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEE-ESKEASAL 815          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Mouse
Match: Grik2 (glutamate receptor, ionotropic, kainate 2 (beta 2) [Source:MGI Symbol;Acc:MGI:95815])

HSP 1 Score: 427.557 bits (1098), Expect = 9.412e-134
Identity = 273/787 (34.69%), Postives = 434/787 (55.15%), Query Frame = 3
Query:  231 SVAVQNANSQLMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLL---NQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAA-----PAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNE-EAQRKQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKS-PVTETNEVI-KPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCD-DNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMEN-NPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKGSI 2552
            +V   N N  L+  N +    T+ ++   SF   +KAC+ L  G+ A+  P     +  + S  N   +PH+ T+ +   S       + LYP+  + +  I   + Q   W  + +++     +++ + L+   +++    K+RQ +  D K  K  L+++ K  K  H + D  +      L       +    + +IFT  D   LD+  ++ +  VN+T F ++N        T +  ++S++E  +   +L      ++ LL        A++ D+++V+    + + +   +    ++C  +  W  G    + I    H  GLTGRI FN+    R  ++L V+ L E G  K G W+ ++ +      K  P   T+ +  + L VTTI+  P+V +K +   +  +D     + G+CIDLL E+   L   + I LV+D KYG         D + +WNGM+ ELI  +ADL VAP+ I+Y REKV+DF+ PFM+LG+SIL+  P    PG+FSFL+PLSP +W+Y++ AY+GVS +++ I+  +PYEW   HPC+ D+   +N F +LNS WF V ALM+QG E  P+A STR+V   WWFFTLIIIS+YTANLAAFLTVE++  PI S +DL  Q  I+YG ++ GA+  FF+++ I TY KM  +M +    V+V+S EEG+ +VL S+  YAFL+ES   ++  +R C L ++G ++DSKGYG+G P GSP RDK+T +IL+LQ+  KL  +  KWW      E  ++KE  ++
Sbjct:   60 AVNTINRNRTLLP-NTTLTYDTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDFSSLSRAILDLV-QFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQ-LPADTKDAKPLLKEM-KRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYSG-VNMTGFRILN--------TENTQVSSIIEK-WSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVS---VAVQQFPQMTVSSLQCNRHKPWRFGTRFMSLIKEA-HWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPSSGLNMTESQKGKPANITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDR----FEGYCIDLLRELSTILGFTYEIRLVEDGKYGA------QDDVNGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGIQRVLTSD--YAFLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEE-ESKEASAL 815          
BLAST of Glutamate receptor ionotropic kainate 3 vs. UniProt/SwissProt
Match: sp|Q13002|GRIK2_HUMAN (Glutamate receptor ionotropic, kainate 2 OS=Homo sapiens OX=9606 GN=GRIK2 PE=1 SV=1)

HSP 1 Score: 428.713 bits (1101), Expect = 2.541e-133
Identity = 270/787 (34.31%), Postives = 434/787 (55.15%), Query Frame = 3
Query:  231 SVAVQNANSQLMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLL---NQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAA-----PAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNE-EAQRKQYNLSVMELTENGFMKKGYWN-GNNFVIFPPKSKSPVTETNEVI-KPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCD-DNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMEN-NPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKGSI 2552
            +V   N N  L+  N +    T+ ++   SF   +KAC+ L  G+ A+  P     +  + S  N   +PH+ T+ +   S       + LYP+  + +  I   + Q   W  + +++     +++ + L+   +++    K+RQ +  D K  K  L+++ + ++  H + D  +      L       +    + +IFT  D   LD+  ++ +  VN+T F ++N        T +  ++S++E  +   +L      ++ LL        A++ D+++V+    + + +   +    ++C  +  W  G    + I    H  GLTGRI FN+    R  ++L V+ L E G  K G W+  +   +   +   P   T+ +  + L VTTI+  P+V +K +   +  +D     + G+CIDLL E+   L   + I LV+D KYG         D + +WNGM+ ELI  +ADL VAP+ I+Y REKV+DF+ PFM+LG+SIL+  P    PG+FSFL+PLSP +W+Y++ AY+GVS +++ I+  +PYEW   HPC+ D+   +N F +LNS WF V ALM+QG E  P+A STR+V   WWFFTLIIIS+YTANLAAFLTVE++  PI S +DL  Q  I+YG ++ GA+  FF+++ I TY KM  +M +    V+V+S EEG+ +VL S+  YAFL+ES   ++  +R C L ++G ++DSKGYG+G P GSP RDK+T +IL+LQ+  KL  +  KWW      E  ++KE  ++
Sbjct:   60 AVNTINRNRTLLP-NTTLTYDTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDFSSLSRAILDLV-QFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQ-LPADTKDAKPLLKEMKRGKEF-HVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYSG-VNMTGFRILN--------TENTQVSSIIEK-WSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVS---VAVQQFPQMTVSSLQCNRHKPWRFGTRFMSLIKEA-HWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPASGLNMTESQKGKPANITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDR----FEGYCIDLLRELSTILGFTYEIRLVEDGKYGA------QDDANGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGIQRVLTSD--YAFLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEE-ESKEASAL 815          
BLAST of Glutamate receptor ionotropic kainate 3 vs. UniProt/SwissProt
Match: sp|P39087|GRIK2_MOUSE (Glutamate receptor ionotropic, kainate 2 OS=Mus musculus OX=10090 GN=Grik2 PE=1 SV=4)

HSP 1 Score: 427.557 bits (1098), Expect = 6.583e-133
Identity = 273/787 (34.69%), Postives = 434/787 (55.15%), Query Frame = 3
Query:  231 SVAVQNANSQLMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLL---NQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAA-----PAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNE-EAQRKQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKS-PVTETNEVI-KPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCD-DNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMEN-NPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKGSI 2552
            +V   N N  L+  N +    T+ ++   SF   +KAC+ L  G+ A+  P     +  + S  N   +PH+ T+ +   S       + LYP+  + +  I   + Q   W  + +++     +++ + L+   +++    K+RQ +  D K  K  L+++ K  K  H + D  +      L       +    + +IFT  D   LD+  ++ +  VN+T F ++N        T +  ++S++E  +   +L      ++ LL        A++ D+++V+    + + +   +    ++C  +  W  G    + I    H  GLTGRI FN+    R  ++L V+ L E G  K G W+ ++ +      K  P   T+ +  + L VTTI+  P+V +K +   +  +D     + G+CIDLL E+   L   + I LV+D KYG         D + +WNGM+ ELI  +ADL VAP+ I+Y REKV+DF+ PFM+LG+SIL+  P    PG+FSFL+PLSP +W+Y++ AY+GVS +++ I+  +PYEW   HPC+ D+   +N F +LNS WF V ALM+QG E  P+A STR+V   WWFFTLIIIS+YTANLAAFLTVE++  PI S +DL  Q  I+YG ++ GA+  FF+++ I TY KM  +M +    V+V+S EEG+ +VL S+  YAFL+ES   ++  +R C L ++G ++DSKGYG+G P GSP RDK+T +IL+LQ+  KL  +  KWW      E  ++KE  ++
Sbjct:   60 AVNTINRNRTLLP-NTTLTYDTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDFSSLSRAILDLV-QFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQ-LPADTKDAKPLLKEM-KRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYSG-VNMTGFRILN--------TENTQVSSIIEK-WSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVS---VAVQQFPQMTVSSLQCNRHKPWRFGTRFMSLIKEA-HWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPSSGLNMTESQKGKPANITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDR----FEGYCIDLLRELSTILGFTYEIRLVEDGKYGA------QDDVNGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGIQRVLTSD--YAFLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEE-ESKEASAL 815          
BLAST of Glutamate receptor ionotropic kainate 3 vs. UniProt/SwissProt
Match: sp|Q38PU3|GRIK2_MACFA (Glutamate receptor ionotropic, kainate 2 OS=Macaca fascicularis OX=9541 GN=GRIK2 PE=2 SV=1)

HSP 1 Score: 427.557 bits (1098), Expect = 7.010e-133
Identity = 271/787 (34.43%), Postives = 433/787 (55.02%), Query Frame = 3
Query:  231 SVAVQNANSQLMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLL---NQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAA-----PAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNE-EAQRKQYNLSVMELTENGFMKKGYWN-GNNFVIFPPKSKSPVTETNEVI-KPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCD-DNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMEN-NPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKGSI 2552
            +V   N N  L+  N +    T+ ++   SF   +KAC+ L  G+ A+  P     +  + S  N   +PH+ T+ +   S       + LYP+  + +  I   + Q   W  + +++     +++ + L+   +++    K+RQ +  D K  K  L+++ + ++  H + D  +      L       +    + +IFT  D   LD+  ++ +  VN+T F ++N        T +  ++S++E  +   +L      ++ LL        A++ D+++V+    + + +   +    ++C  +  W  G    + I    H  GLTGRI FN+    R  ++L V+ L E G  K G W+  +   +   +   P   T+ +  + L VTTI+  P+V +K +   +  +D     + G+CIDLL E+   L   + I LV+D KYG         D + +WNGM+ ELI  +ADL VAP+ I+Y REKV+DF+ PFM+LG+SIL+  P    PG+FSFL+PLSP +W+YV+ A +GVS +++ I+  +PYEW   HPC+ D+   +N F +LNS WF V ALMRQG E  P+A STR+V   WWFFTLIIIS+YTANLAAFLTVE++  PI S +DL  Q  I+YG ++ GA+  FF+++ I TY KM  +M +    V+V+S EEG+ +VL S+  YAFL+ES   ++  +R C L ++G ++DSKGYG+G P GSP RDK+T +IL+LQ+  KL  +  KWW      E  ++KE  ++
Sbjct:   60 AVNTINRNRTLLP-NTTLTYDTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDFSSLSRAILDLV-QFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQ-LPADTKDAKPLLKEMKRGKEF-HVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYSG-VNMTGFRILN--------TENTQVSSIIEK-WSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVS---VAVQQFPQMTVSSLQCNRHKPWRFGTRFMSLIKEA-HWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPASGLNMTESQKGKPANITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDR----FEGYCIDLLRELSTILGFTYEIRLVEDGKYGA------QDDANGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFSPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMRQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGIQRVLTSD--YAFLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEE-ESKEASAL 815          
BLAST of Glutamate receptor ionotropic kainate 3 vs. UniProt/SwissProt
Match: sp|P42260|GRIK2_RAT (Glutamate receptor ionotropic, kainate 2 OS=Rattus norvegicus OX=10116 GN=Grik2 PE=1 SV=2)

HSP 1 Score: 427.172 bits (1097), Expect = 8.116e-133
Identity = 272/787 (34.56%), Postives = 433/787 (55.02%), Query Frame = 3
Query:  231 SVAVQNANSQLMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLL---NQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAA-----PAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNE-EAQRKQYNLSVMELTENGFMKKGYWN-GNNFVIFPPKSKSPVTETNEVI-KPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCD-DNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMEN-NPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKGSI 2552
            +V   N N  L+  N +    T+ ++   SF   +KAC+ L  G+ A+  P     +  + S  N   +PH+ T+ +   S       + LYP+  + +  I   + Q   W  + +++     +++ + L+   +++    K+RQ +  D K  K  L+++ K  K  H + D  +      L       +    + +IFT  D   LD+  ++ +  VN+T F ++N        T +  ++S++E  +   +L      ++ LL        A++ D+++V+    + + +   +    ++C  +  W  G    + I    H  GLTGRI FN+    R  ++L V+ L E G  K G W+  +   +   +   P   T+ +  + L VTTI+  P+V +K +   +  +D     + G+CIDLL E+   L   + I LV+D KYG         D + +WNGM+ ELI  +ADL VAP+ I+Y REKV+DF+ PFM+LG+SIL+  P    PG+FSFL+PLSP +W+Y++ AY+GVS +++ I+  +PYEW   HPC+ D+   +N F +LNS WF V ALM+QG E  P+A STR+V   WWFFTLIIIS+YTANLAAFLTVE++  PI S +DL  Q  I+YG ++ GA+  FF+++ I TY KM  +M +    V+V+S EEG+ +VL S+  YAFL+ES   ++  +R C L ++G ++DSKGYG+G P GSP RDK+T +IL+LQ+  KL  +  KWW      E  ++KE  ++
Sbjct:   60 AVNTINRNRTLLP-NTTLTYDTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDFSSLSRAILDLV-QFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQ-LPADTKDAKPLLKEM-KRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYSG-VNMTGFRILN--------TENTQVSSIIEK-WSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVS---VAVQQFPQMTVSSLQCNRHKPWRFGTRFMSLIKEA-HWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPASGLNMTESQKGKPANITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDR----FEGYCIDLLRELSTILGFTYEIRLVEDGKYGA------QDDVNGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGIQRVLTSD--YAFLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEE-ESKEASAL 815          
BLAST of Glutamate receptor ionotropic kainate 3 vs. UniProt/SwissProt
Match: sp|Q01812|GRIK4_RAT (Glutamate receptor ionotropic, kainate 4 OS=Rattus norvegicus OX=10116 GN=Grik4 PE=1 SV=1)

HSP 1 Score: 419.853 bits (1078), Expect = 1.765e-129
Identity = 243/659 (36.87%), Postives = 371/659 (56.30%), Query Frame = 3
Query:  579 IIHKSDNCIMKYEYLLNQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNEEAQRKQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKSPVTETNEVIKPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCDDNGSRQ--NQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYM-ENNPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKG 2546
            +I     C++  E LL QF            D  ++   L K  +  K    ++          L+  +   +    +++IFT+ +  +  +    ++++VNI  FS+ N S        H       +++ +S + +      T    + A++ D++  ++  +  L + Q +  +P+ C +   W  G SL N +  V+ + GLTG I FN + QR  Y L +++ T NGF + G W+    +    +  +     +     L VTTI+  P++  K N  D++ +D     + GFC+D+L E+   LR N+ I LV D  YG        P+ +  W GM+GELI+++ADL VA +TI+ EREKV+DF+ PFM+LG+SIL+       PG FS L P SP VW++++ AY+ VS +++ ++ +TPYEW   HPC         NQ+++ NSLWF V   M+QG    P+A STR VS  WW FTLIIIS+YTANLAAFLTV+++ +PI+SV+DL +Q  I+YGT+ GG+S  FF+ +  QTY++M  YM    P V V+STEEG+ +VL SN  YAFLLES MN+YY++R C L ++G +LD+KGYGIG P GS  RD+   +IL+LQ++ +L  L  KWW      +  D + KG
Sbjct:  164 LICAKAECLLNLEKLLRQFLISKDTLSVRMLDDTRDPTPLLKEIRDDKTATIIIHANASMSHTILLKAAELGMVSAYYTYIFTNLEFSLQRMDSL-VDDRVNILGFSIFNQS--------HAFFQEFSQSLNQSWQENCDHVPFTGPALSSALLFDAVYAVVTAVQELNRSQEIGVKPLSCGSAQIWQHGTSLMNYLRMVE-LEGLTGHIEFNSKGQRSNYALKILQFTRNGFRQIGQWHVAEGLSMDSRLYASNISDSLFNTTLVVTTILENPYLMLKGNHQDMEGNDR----YEGFCVDMLKELAEILRFNYKIRLVGDGVYGV-------PEANGTWTGMVGELIARKADLAVAGLTITAEREKVIDFSKPFMTLGISILYRVHMGRRPGYFSSLDPFSPGVWLFMLLAYLAVSCVLFLVARLTPYEWYSPHPCAQGRCNLLVNQYSLGNSLWFPVGGFMQQGSTIAPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPIESVDDLADQTAIEYGTIHGGSSMTFFQNSRYQTYQRMWNYMYSKQPSVFVKSTEEGIARVLNSN--YAFLLESTMNEYYRQRNCNLTQIGGLLDTKGYGIGMPVGSVFRDEFDLAILQLQENNRLEILKRKWWEGGKCPKEEDHRAKG 799          
BLAST of Glutamate receptor ionotropic kainate 3 vs. TrEMBL
Match: A0A4E0RD83 (Glutamate receptor ionotropic kainate 3 OS=Fasciola hepatica OX=6192 GN=D915_002434 PE=3 SV=1)

HSP 1 Score: 599.356 bits (1544), Expect = 0.000e+0
Identity = 352/902 (39.02%), Postives = 536/902 (59.42%), Query Frame = 3
Query:  111 SFPFLLMLLGRPILSKELSKIYLTIGVIFEANDDVSRKVVSVAVQNANSQLMRYNYSFRI-----VTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLLNQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLIND---------SLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTT-WNQGISLFNAITSV--DHMYGLTGRIVFNEEAQRKQYNLSVMELTENGFMKKGYWNGNN---FVIFPPKSKSPVTETNEVIKPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCDDNGS-RQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCD-TKEKGSIPTALDVHQXXXXXXXXXXXXXXASMVSVIELYVTYCEGTCKWNVPFHIYFQKELQFAVRFMSSSKK 2750
            +F F  + L R +     S IY  IGV+F   D+         +Q AN Q++R N + ++     + E V     F   ++AC LL+ G+VAL  P +   S+ L S +NRF +P++ T+     +  +Y ++  +YP  D +   +++Y+T++E W  + IIH+    ++KY  L+N+FE   K++ W   +    +  L +++   + ++FLVD+P W++RDFL+M   HN+TG  +++ FTDWD   +DL+ FK++    I  FS+++           L+ + +  H   +       E   L     +NT+      ++ DSI +L  GL+ L K + +  Q + C      W  G+SL NA+ S   + + G TG+  F+ E QR  ++++ ++LTE GF+  G WN +     V  PPK K P      +   L+VTT    PF+  K      K   T  DAW G+CIDLL+EI   +  N+++HL  D  YG+   +   P+G+E ++G++GELI +E D+ VA  TI+YEREKVVDF+TP+M++G SI+F  P+ + P LFSFL PL+P VW YV++ Y  V + ++  S ++PYEW   H CDD G   +NQF +LNS ++ ++AL+ QG E  PQA+STR+++  WWFF LIII+TYTANLAAFLTVE    PI+S EDL NQ  IKYGT+  G+S  FF+   + T+KKM  +M+  P+ +   TE GV++V    G YAF+LESA N+YY +R+C+L++VG +LDSKGYGIGFP GSP RD+++ +IL+LQ  Q+L  L  KWWNE+NITEPC+  +E    P+ L V Q+GGVF++L VGF+   +VS++E  +   +   K          +EL FAVR +++SK+
Sbjct:   59 AFQFEDVSLRRRVTRNVKSVIY--IGVLFMQGDEALESAFRTGIQAAN-QVLRSNEALQLHQLEPLIEVVPKENMFVATQQACKLLERGIVALYGPRNAAFSKALLSLANRFGVPYVETQWNVSPTLDAYALS--MYPKADTFGEGLYEYLTRVEKWRHVTIIHEQPESLLKYVSLINKFEDGLKVKSWT-ANSAATRAMLAEISTGNE-RNFLVDVPTWQVRDFLVMAYAHNMTGTQYTYFFTDWDVNFMDLTAFKVSMGAQIKTFSILSKVGITESLQRGLINARQANHPGTSRTTGRQMERPFLGLGPEMNTHF----GLLYDSILLLAHGLVTLTKTRSLLPQKLSCERPPGLWPLGLSLINAMKSTRPEMVRGYTGQFRFDREGQRTLFDITTLDLTEGGFVPTGIWNVDEQMKIVTRPPK-KLPHKMIKNMPIVLKVTTKQDPPFMIIKKTDAYGKPLITP-DAWQGYCIDLLDEISKKVGFNYTVHLTPDGNYGS---STILPNGTEIYDGIMGELIRREVDMAVAAFTITYEREKVVDFSTPWMTIGGSIMFTRPKSQKPSLFSFLQPLAPQVWFYVLAIYFAVCVCMFISSRLSPYEWNSPHACDDGGDMTKNQFTLLNSFYYHISALLNQGTELAPQATSTRLLTGVWWFFALIIIATYTANLAAFLTVENTKSPIESAEDLANQDKIKYGTISSGSSRDFFKTTTLSTFKKMGAFMDKYPEYLADRTEIGVERV--KQGNYAFILESAWNEYYVQRDCSLMQVGALLDSKGYGIGFPQGSPWRDRVSSAILQLQNDQQLDKLKRKWWNEYNITEPCNLLRESSKAPSPLGVEQIGGVFIMLLVGFVVGFLVSIVEFVIATRD---KNRSEMLKAMWRELTFAVRCLTTSKR 939          
BLAST of Glutamate receptor ionotropic kainate 3 vs. TrEMBL
Match: A0A095BTF9 (Glutamate receptor ionotropic, kainate 3 OS=Schistosoma haematobium OX=6185 GN=MS3_00235 PE=3 SV=1)

HSP 1 Score: 593.193 bits (1528), Expect = 0.000e+0
Identity = 364/885 (41.13%), Postives = 534/885 (60.34%), Query Frame = 3
Query:  153 SKELSKIYLTIGVIFEANDDVSRKVVSVAVQNANSQLMRY----NYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLLNQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSL---RTRHKNL---NSLMENIFESRKLSKKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTT-WNQGISLFNAITSV--DHMYGLTGRIVFNEEAQRKQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKSPVTETNEVIKP--LRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCDDNG-SRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCD-TKEKGSIPTALDVHQXXXXXXXXXXXXXXASMVSVIELYVTY--CEGTCKWNVPFHIYFQKELQFAVRFMSSSKK 2750
            S+E+  + + IGVI    D  + K     VQ AN  L +     +Y    + + V  +  F   ++AC +L  G++AL  P S   S+ L S +NRF +P++ T         +Y   I L+P+ ++Y   +++Y+TQ+E W  M +I+     ++K+  L+N FE   K++ W   +    +  + +L  S   K+F+VD+P W++ +FL+M   HN+TG  ++FIFTDWD  ILDLS FKI+    I A S+I    VTSL   +T    +      +ENI      S K F N N     ++I DS+ +L  GL  + + +P+  Q + C      W  G+SL NA+ SV  + + GLT    F++   R  ++L+ +ELT+ GF   G WN +  +    +    + +    IK   L+VTTI   PF+         +   T  DAW G+CIDLLN I +D+  N+++H+  D +YG+ +D     +G+  +NG++GELI +EAD+ VA  TI+YEREK+VDF+TP+M+LG SILF  P+ + P LFSFL PLSP VW+YV   Y+ V L ++  + ++P+EW   HPC++ G +R+NQF +LNS ++ V+AL+ QG E  P A+STR+++  WWFF LIII+TYTANLAAFLTVE +  PI+S EDL NQ+ IKYGTLK G+S  FF  + + T+KKM ++M+  PD  V +T+EG+++VL+  G YAF+LES  N+YY +R+C L +VG +LDSKGYGIGFP GSP RD ++KSILKLQ +Q L+ L   WWNEFNITEPC   +E G  P+ L V QVGGVF++L +GF     VS+IE  V     + T  W         KEL+FA R +++S++
Sbjct:   43 SREVKSV-IYIGVILTDEDRDTEKAFENGVQAANEVLGQSGTLSSYQLEPIIQFVPKDNVFVATQQACKILDRGIIALYGPSSTSLSQALLSLANRFGLPYVETHWNMIPRKTTYA--IHLHPSIESYGIGLYEYLTQVEKWKRMTLIYNKPESLLKFATLVNNFEGILKIKSWDE-NASGARAMMAELG-SGLEKNFIVDIPSWQVTNFLVMAYVHNMTGFQYTFIFTDWDIAILDLSAFKIDVGARIKAVSIIPK--VTSLDINKTPQPEILPYKKTLENI-----ASSKDFSNGNPTIQFSLIYDSLILLAHGLSTVTRTRPLLPQKLSCERPPGLWPLGLSLINAVKSVASETIRGLTSPFRFDKHGLRTLFDLTTLELTQGGFKPTGVWNIDERMKVAKQPAITLPKQLPKIKGVVLKVTTIPDAPFMIPIKFDAYDRPLGTP-DAWMGYCIDLLNHIASDVGFNYTVHITPDRQYGSGIDVG---NGTIFYNGIMGELIREEADMAVAGFTITYEREKLVDFSTPWMTLGGSILFTRPKSQKPSLFSFLQPLSPQVWLYVGFTYLAVCLCLFVAARLSPHEWTATHPCEEGGDTRKNQFTLLNSFYYNVSALLNQGTELAPHATSTRLLTGVWWFFALIIIATYTANLAAFLTVENMKSPIESAEDLANQEKIKYGTLKSGSSRDFFRTSSLPTFKKMGEFMDKYPDATVSTTQEGIERVLQ--GNYAFILESTWNEYYAQRDCRLTQVGTLLDSKGYGIGFPQGSPWRDPVSKSILKLQNAQILAKLKRIWWNEFNITEPCSLLRESGKAPSPLGVEQVGGVFIVLLIGFFMGFAVSIIEFLVATRDQQKTAVWRG-----MWKELKFATRCLTTSRR 904          
BLAST of Glutamate receptor ionotropic kainate 3 vs. TrEMBL
Match: A0A3Q0KQ55 (Putative glutamate receptor, kainate OS=Schistosoma mansoni OX=6183 PE=3 SV=1)

HSP 1 Score: 591.267 bits (1523), Expect = 0.000e+0
Identity = 363/891 (40.74%), Postives = 535/891 (60.04%), Query Frame = 3
Query:  153 SKELSKIYLTIGVIFEANDDVSRKVVSVAVQNANSQLMRY----NYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLLNQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSL---RTRHKNL---NSLMENIFESRKLSKKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTT-WNQGISLFNAITSV--DHMYGLTGRIVFNEEAQRKQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKSPVTETNEVIKP-----LRVTTIVSLPFVFYKDNSPDIKEHDTSI---DAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCDDNG-SRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCD-TKEKGSIPTALDVHQXXXXXXXXXXXXXXASMVSVIELYVTY--CEGTCKWNVPFHIYFQKELQFAVRFMSSSKK 2750
            S+E+  + + IG+I    D  + K     VQ AN  L +     +Y    + + V  +  F   ++AC +L  G++AL  P S   S+ L S +NRF +P++ T         +Y   I L+P+ ++Y   +++Y+TQ+E W  M +I+     ++K+  L+N FE   K++ W   +    +  + +L  S   K+FLVD+P W++ +FL+M   HN+TG  ++FIFTDWD   LDLS FKI+    I A S+I    VTSL   +T    +      +EN   S+ LS     N N     ++I DS+ +L  GL  + + +P+  Q + C      W  G+SL NA+ SV  + + GLT    F++   R  ++L+ +ELT+ GF   G WN +  +     +K PV    + +       L+VTTI   PF+           +D  +   DAW G+CIDLLN I +D+  N+++H+  D +YG+ +D     +G+  +NG++GELI +EAD+ VA  TI+YEREK+VDF+TP+M+LG SILF  P+ + P LFSFL PLSP VW+YV   Y+ V L ++  + ++P+EW   HPC++ G +R+NQF +LNS ++ V+AL+ QG E  P A+STR+++  WWFF LIII+TYTANLAAFLTVE +  PI+S EDL NQ+ IKYGTLK G+S  FF  + + T+KKM ++M+  PD  V +T+EG+++VL+  G YAF+LES  N+YY +R+C L +VG +LDSKGYGIGFP GSP RD ++KSILKLQ +Q L+ L   WWNEFNITEPC   +E G  P+ L V QVGGVF++L +GF     VS+IE  V     + T  W         KEL+FA R +++S++
Sbjct:   43 SREIKSV-IYIGIILTDEDRETEKAFENGVQAANEVLSQSGTLSSYQLEPIIQFVPKDNVFVATQQACKILDRGIIALYGPSSTSLSQALLSLANRFGLPYVETHWSMISRKTTYA--IHLHPSIESYGLGLYEYLTQVEKWKRMTLIYNKPESLLKFTTLVNNFEGILKIKSWDE-NASGARAMMAELG-SGLEKNFLVDIPSWQVTNFLVMAYVHNMTGYQYTFIFTDWDIATLDLSAFKIDVGARIKAISIIPK--VTSLDINKTPQPEMLLYKKTLENTAGSKDLS-----NGNPTIQFSLIYDSLILLAHGLSTVTRTRPLLPQKLSCERPPGLWPLGLSLINAVKSVASETVRGLTSPFRFDKHGLRTLFDLTTLELTQGGFKPTGVWNIDERMKV---AKQPVITLPKQLPKIKGVVLKVTTIPDAPFMI----PIKFDAYDRPLGTPDAWMGYCIDLLNHIASDVGFNYTVHITPDRQYGSGIDVG---NGTIFYNGIMGELIREEADMAVAGFTITYEREKLVDFSTPWMTLGGSILFTRPKSQKPSLFSFLQPLSPQVWLYVGFTYLAVCLCLFVAARLSPHEWTATHPCEEGGDTRKNQFTLLNSFYYNVSALLNQGTELAPHATSTRLLTGVWWFFALIIIATYTANLAAFLTVENMKSPIESAEDLANQEKIKYGTLKSGSSRDFFRTSSLPTFKKMGEFMDKYPDATVSTTQEGIERVLQ--GNYAFILESTWNEYYAQRDCRLTQVGTLLDSKGYGIGFPQGSPWRDPVSKSILKLQNAQILAKLKRIWWNEFNITEPCSLLRESGKAPSPLGVEQVGGVFIVLLIGFFMGFAVSIIEFLVATRDQQKTAVWRG-----MWKELKFATRCLTTSRR 904          
BLAST of Glutamate receptor ionotropic kainate 3 vs. TrEMBL
Match: A0A4Z2CN37 (Glutamate receptor ionotropic, kainate 3 isoform 5 OS=Schistosoma japonicum OX=6182 GN=EWB00_009241 PE=3 SV=1)

HSP 1 Score: 583.948 bits (1504), Expect = 0.000e+0
Identity = 354/882 (40.14%), Postives = 527/882 (59.75%), Query Frame = 3
Query:  153 SKELSKIYLTIGVIFEANDDVSRKVVSVAVQNANSQLMRY----NYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLLNQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTT-WNQGISLFNAITSV--DHMYGLTGRIVFNEEAQRKQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKSPVTETNEVIKP--LRVTTIVSLPFVFYKDNSPDIKEHDTSI---DAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCD-DNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCD-TKEKGSIPTALDVHQXXXXXXXXXXXXXXASMVSVIELYVTY--CEGTCKWNVPFHIYFQKELQFAVRFMSSSKK 2750
            S+E+  + + IGVI    D    +     VQ AN  L +     +Y    + + V  +  F   ++AC +L  G++AL  P S   ++ L S +NRF +P++ T     +   +Y   I L+P+ ++Y   +++Y+TQ+E W  M +I+     ++K+  L+N FE   K++ W   +    +  + +L  S   K+FLVD+P W++ +FL+M   HN+TG  ++FIFTDWD   +DLS FKI+    I A S+I    V  +    +   S    + E   +S     N N     ++I DS+ +L  GL  + + +P+  Q + C      W  G+SL NA+ SV  + + GLT    F++   R  ++L+ +ELT+ GF   G WN +  +    +    + +    IK   L+VTTI   PF+           +D  +   DAW G+CIDLLN I +D+  N+++H+  D +YG+ +D     +G+  +NG++GELI +EAD+ VA  TI+YEREK+VDF+TP+M+LG SILF  P+ + P LFSFL PLSP VW+YV   Y+ V L ++  + ++P+EW   HPC+ D  +R+NQF +LNS ++ V+AL+ QG E  P A+STR+++  WWFF LIII+TYTANLAAFLTVE +  PI+S EDL NQ+ IKYGTLK G+S  FF  + + T+KKM ++M+  PD  V +T+EG+++VL+  G YAF+LES  N+YY +R+C L +VG +LDSKGYGIGFP GSP RD ++KSILKLQ +Q L+ L   WWNEFNITEPC   +E G  P+ L V QVGGVF++L +GF     VS+IE  V     + T  W         KEL+FA R +++S++
Sbjct:   51 SREVKSV-IYIGVILTDEDKNIGRAFENGVQAANEVLSQSGTLSSYQLEPIIQFVPKDNVFKATQQACKILDRGIIALYGPSSTSLAQALLSLANRFGLPYVETHWSMVQRKTTYA--IHLHPSIESYGIGLYEYLTQVEKWKRMTLIYNKPESLLKFTTLVNNFEGILKIKSWDE-NASGARAMMAELG-SGLEKNFLVDIPSWQVANFLVMAYVHNMTGYQYTFIFTDWDITTIDLSAFKIDVGARIKAISIIPKVTVLDINKARQPEMSFYRKLPED--VSSNIIPNGNPTIQFSLIYDSLVLLANGLCTVTRTRPLLPQKLSCERPPGLWPLGLSLINAVKSVASETVRGLTSPFRFDKHGLRTLFDLTTLELTQGGFKPTGVWNIDERMKVAKQPAITLPKQLPKIKGVVLKVTTIPDAPFMI----PIKFDAYDRPLGTPDAWMGYCIDLLNHIASDVGFNYTVHITPDRQYGSGMDFG---NGTIFYNGIMGELIREEADMAVAGFTITYEREKLVDFSTPWMTLGGSILFTRPKSQKPSLFSFLQPLSPQVWLYVGFTYLAVCLCLFVAARLSPHEWTATHPCEVDGDTRKNQFTLLNSFYYNVSALLNQGTELAPHATSTRLLTGVWWFFALIIIATYTANLAAFLTVENMKSPIESAEDLANQEKIKYGTLKSGSSRDFFRTSSLPTFKKMGEFMDKYPDATVSTTQEGIERVLQ--GNYAFILESTWNEYYAQRDCRLTQVGTLLDSKGYGIGFPQGSPWRDPVSKSILKLQNAQILAKLKRIWWNEFNITEPCSLLRESGKAPSPLGVEQVGGVFIVLLIGFFMGFAVSIIEFLVATRDQQKTAVWR-----GMWKELKFATRCLTTSRR 911          
BLAST of Glutamate receptor ionotropic kainate 3 vs. TrEMBL
Match: A0A4S2LMY3 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_007409 PE=3 SV=1)

HSP 1 Score: 583.178 bits (1502), Expect = 0.000e+0
Identity = 353/890 (39.66%), Postives = 532/890 (59.78%), Query Frame = 3
Query:  165 SKIYLTIGVIFEANDDVSRKVVSVAVQNANSQLMR----YNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLLNQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKN------------LNSLMENIFESRKLSKKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTT-WNQGISLFNAITSV--DHMYGLTGRIVFNEEAQRKQYNLSVMELTENGFMKKGYWNGNNFV-----IFPPKSKSPVTETNEVIKPLRVTTIVSLPFVFY--KDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCD-DNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCD-TKEKGSIPTALDVHQXXXXXXXXXXXXXXASMVSVIELYVTYCEGTCKWNVPFHIYFQKELQFAVRFMSSSKK 2750
            +K  + IGVI    D+        +V  AN  L +      +    + E V  +  F   ++AC L+ NG+VAL  P     S+ L S +NRF IP++ T      +  +Y  ++ ++P   ++   +++Y+TQ+E W  M IIH     ++K+  L+N FE   K++ W  G     K  + +L+ S   K FL+D+P W+ RDFL+M   HN+TGP  S+ FTDWD  +LDL+ FK++    I   S+++ S    ++   +N            +   +E+     KL     +NT       I+ DS  +L  GL+ + + +P+  Q + C      W  G+SL NA+ SV  D + G+TG+  F+ + QR  ++L+ +ELTE GF   G WN +  +     I    +K P +  N+V+  L VTT    PF+     D   +   H    DAW G+C +LL+ + A++  N++I + KD++YG+    +T P+G+  +NG++G+LI KE D+ VA  TI+YEREK+VDF+TP+M++G SILF  P+ + P LFSFL PL+P VW+YV++ Y+ V L ++  + ++PYEW   HPCD D+   +NQF +LNS ++ ++AL+ QG+E  PQA+STR+++  WWFF LIII+TYTANLAAFLTVE    PI+SVEDL NQ+ IKYGTL+ G+S  FF    I  +KKM ++M+  PDV    T  G+++V    G YAF+LES+ N+YY +R+C+L++VG +LDSKGYGIGFP GS  RD ++K+ILKLQ +Q L+NL  KWWNE+NITEPC   KE+   P+ L V QVGGVF++L VGF+   +VS+IE  +   +   +  V       +EL+FA R +++SK+
Sbjct:   59 AKPVIYIGVILAQGDEDMEAAFRTSVDAANQVLAQSVNLRTHQLEPIIEVVSRDNVFLATQQACKLMTNGIVALFGPNVRALSQALLSLANRFGIPYVETYWNHYTTPGTY--SVSMHPKVHSFGLGLYEYLTQVEKWRRMNIIHNQPEKLLKFTTLVNSFEGTAKVKTWNSGSASA-KSMMAELSSS-SEKTFLIDIPAWQARDFLVMAFVHNMTGPQFSYFFTDWDVGLLDLTAFKVDAGAQIKTISILSKS---GIKKAMQNPGVYQASSVPLPIPQTIESNLGPPKLGITGVLNTQF----GILYDSFLLLAHGLVTVTRTRPLLPQKLSCERPPGLWPLGLSLINAMKSVSPDVVGGITGQFRFDRDGQRTMFDLTTLELTEGGFTPSGVWNIDERMKVVKKIIKRPNKHP-SNLNDVV--LSVTTKADPPFMISISSDAYGNPLPHP---DAWTGYCKELLDALAAEVGFNYTIQIPKDDQYGSA---KTLPNGTVVYNGIMGQLIRKEVDMAVAGFTITYEREKLVDFSTPWMTIGGSILFTRPKSQKPSLFSFLQPLAPKVWLYVVAIYLAVCLCMFAAARLSPYEWNAPHPCDEDSDVTKNQFTLLNSFYYYISALLNQGVELAPQATSTRLLTGVWWFFGLIIIATYTANLAAFLTVENTKSPIESVEDLANQEKIKYGTLRSGSSRDFFRTTTIPVFKKMGEFMDKYPDVTTPDTRTGIERV--RAGGYAFILESSWNEYYVQRDCSLMQVGALLDSKGYGIGFPQGSVWRDPVSKAILKLQNNQVLANLKRKWWNEYNITEPCSLLKERNKAPSPLGVEQVGGVFIMLLVGFLLGFIVSIIEFIIATRD---QKRVTVLKGMWRELKFASRCLTTSKR 923          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Cavefish
Match: si:ch211-264f5.8 (si:ch211-264f5.8 [Source:ZFIN;Acc:ZDB-GENE-081104-209])

HSP 1 Score: 425.631 bits (1093), Expect = 3.649e-132
Identity = 275/788 (34.90%), Postives = 420/788 (53.30%), Query Frame = 3
Query:  219 RKVVSVAVQNANSQLMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRH-LSSFSNRFHIPHLVTKCQFPESSASYP----MNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLLNQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAAPAI----IIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNEEAQRKQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKSPVTETNEVIKPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPC--DDNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYM-ENNPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKG 2546
            R  +++A +N NS          ++   +  +  +      C +L  G+V++I P S   S   +S       IPH+      PE +   P     ++ LYP+ +  +  I   +         +I  K++ C+++ E L+ +F            D   +   L K  +  K    ++D         L   S   +T   + +I T  D  +L L    ++++ NI  FS++N+S            +        S  LS +   + +    PA+    + D+++V++  +  L + Q +  +P+ CT++  W  G SL N +  V++  GLTGR+ FN + QR  Y L V+E    G  + G W  NN +     S           K L VTTI+  P+V  K+N  D + +D     + GFC+D+L E+   L+ +F I LV D  YG        P+GS  W GM+GELI+++ADL VA  TI+ EREKV+DF+ PFM+LG+SIL+       PG FSFL P SP VW++++ AY+ VS +++  + ++PYEW   HPC  +     +NQ+ + NSLWF V   M+QG E  P+A STR VS  WW FTLIIIS+YTANLAAFLTV+++ +PI+S +DL +Q  I+YGT+ GG++  FF  +  QTY++M  YM    P V V+STEEG+ +VL  N KYAFLLES MN+Y++   C L ++G +LD+KGYGIG P GSP RD++T  +L+LQ++ +L  L  +WW      +  D + KG
Sbjct:   16 RLALALARENINS----------LMEGPLQRDSQYETTDTMCQILPKGVVSVIGPASSPASASTVSHICGEKEIPHIKIG---PEETPRLPYLRFASVTLYPSNEDLSMAIGAILRSFNYPTASLICAKAE-CLLRLEELVRRFLISRDTLSVRMLDESLDPTPLLKEIRDDKVATIIIDANASVSILILKKASELGMTSAFYKYILTTMDFPLLRLDDV-VDDQSNIVGFSMLNNS------------HPFYLEFIRSLNLSWREGCDLSPYPGPALSSALMFDAVHVVVGAVRELNRSQEIGVKPLSCTSSLIWQHGTSLMNYLRMVEY-DGLTGRVEFNSKGQRTNYTLCVLEKFRGGHREIGIWYSNNTLAMNSTSLDNNMSHTLANKTLTVTTILENPYVMRKENYQDFEGNDQ----YEGFCVDMLRELSDILKFSFRIKLVDDGLYGA-----PEPNGS--WTGMVGELINRKADLAVAGFTITSEREKVIDFSKPFMTLGISILYRVHIGRKPGYFSFLDPFSPAVWLFMLLAYLAVSCVLFLAARLSPYEWYNPHPCLRERRDLLENQYTLGNSLWFPVGGFMQQGSEIMPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPIESADDLADQTNIQYGTIHGGSTMTFFMNSRYQTYQRMWNYMYSKQPIVFVKSTEEGIARVL--NSKYAFLLESTMNEYHRRHNCNLTQIGGLLDTKGYGIGMPLGSPFRDEITLGVLQLQENNRLEILKRRWWEGGECPKEEDHRAKG 762          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Cavefish
Match: ENSAMXT00000004586.2 (glutamate receptor ionotropic, kainate 2-like [Source:NCBI gene;Acc:103044887])

HSP 1 Score: 421.009 bits (1081), Expect = 2.106e-131
Identity = 267/762 (35.04%), Postives = 429/762 (56.30%), Query Frame = 3
Query:  318 SFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLL---NQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPY----WEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAA-----PAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNE-EAQRKQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKSPVTETNEVI--KPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCD-DNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMEN-NPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKGSI 2552
            SF   RKAC  L  G+ A+  P     +  + S SN   +PH+ T+ +   S       + LYP+  + +  I   +     W  + +++     +++ + L+   +++    K+RQ +  + K  K  L+ + KS++  H + D  +    W ++  L M     +    + +IFT  D   LD+  ++ +  VN+T F ++N        T    ++S++E  +   +L      ++ LL        A++ D+++V+    + + + Q +    ++C  +  W  G   F ++       GLTGR++FN+    R +++L V+ L E+G  K G W   N +      KS +T     +  K LRV TI+  P+V +K +   +  +D     + G+C+DLL E+ + L   + I LV+D KYG + ++      + +WNGM+ EL+  +ADL VAP+ I+Y REKV+DF+ PFM+LG+SIL+  P    PG+FSFL+PLSP +W+Y++ AY+GVS +++ I+  +PYEW   HPC+ D+   +N F +LNS WF V ALM+QG E  P+A STR+V   WWFFTLIIIS+YTANLAAFLTVE++  PI S +DL  Q  I YG ++ G++ AFF++  I TY KM ++M +    VMV+S EEG+ +VL S+  YAFL+ES   ++  +R C L ++G ++DSK YG+G P GSP RDK+T +IL+LQ+  KL  +  KWW      E  ++KE  ++
Sbjct:   90 SFEASRKACEQLSLGVAAIFGPSHSSSANAVQSISNALGVPHIQTRWKHQVSDNRDSYYVSLYPDFSSLSRAILDLV-HFFRWDSVTVVYDDSTGLIRLQELIKAPSRYNIRLKIRQ-LPAETKDAKPLLKDMKKSKEF-HVIFDCSHEMAAWILKQALSM----GMMTEYYHYIFTTLDLFALDMEPYRYSG-VNMTGFRILN--------TESPQVSSIVEK-WSMERLQAPPKPDSGLLDGFMTTDAALMFDAVHVVA---VAVQQSQQITVSSLQCNRHKPWRFG-GRFMSLIKEASWDGLTGRVLFNKTNGLRTEFDLDVISLKEDGLEKIGTWEPVNGLNMTEHHKSKMTNVTNSLSNKSLRVATILEEPYVMFKKSDKPLCGNDR----FEGYCVDLLRELASILGFRYEIQLVEDGKYGALEES------TGQWNGMVRELMDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPHPCNPDSDMVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIPYGVVEDGSTMAFFKKTKISTYDKMWEFMNSRRQSVMVKSVEEGIQRVLTSD--YAFLMESTTIEFVTQRNCNLTQIGGLIDSKAYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEE-ESKEASAL 817          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Cavefish
Match: grik1a (glutamate receptor ionotropic, kainate 1 [Source:NCBI gene;Acc:103038234])

HSP 1 Score: 419.853 bits (1078), Expect = 5.137e-131
Identity = 281/820 (34.27%), Postives = 443/820 (54.02%), Query Frame = 3
Query:  162 LSKIYLT------IGVIFEANDDVSRKVVSVAVQ------NANSQLMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLL---NQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLS----KKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNE-EAQRKQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKSPVTETNEVI-KPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCDDNGS-RQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNPD-VMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKGSI 2552
            +SK+YL+      IG IFE  ++    V  +A +      N N  LM  N +     + V+   SF   R+ C+ L  G+ A+  P        + S  N   +PH+ T+ + P         I LYP   + +  I   +T  + W  + ++++    +M+ + L+   ++     ++RQ   G     +  L+++ K ++  + + D       + L  + +  +    + F FT  D   LDL  ++ +  VN+TAF L        L+     + S+++     R+LS    +   +   +  A A++ D++ ++     R  ++       ++C  +  W  G    N         GLTGRI+ N+ +  RK ++L ++ L E+G  K G WN  + +    K ++    T+ +  + L VTTI+  P+V YK +   +  +D     + G+C+DLL E+   L  N+ + LV D KYG   D         +WNGM+ ELI   ADL VAP+TI+Y REKV+DF+ PFM+LG+SIL+  P    PG+FSFL+PL+P +W+YV+ A +GVS +++ I+  TPYEW   HPC+ +    +N F +LNSLWF VAALMRQG E  P+A STR+V   WWFFTLIIIS+YTANLAAFLTVE++  PI S +DL  Q  I+YG ++ G++  FF+++ I TY+KM  +M +  +  +V++T EG+ +VL ++  YA L+ES   +Y  +R C L +VG ++DSKGYG+G P GSP RDK+T +IL+LQ+  KL  +  KWW      E  D KE  ++
Sbjct:   26 MSKLYLSDQQVLRIGGIFETRENEPVSVDELAFKFAVTSINRNRTLMP-NTTLTYDIQRVNLFDSFEASRRVCDQLALGVAAVFGPAHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDTFFINLYPEHTSISRAILDVVTYYK-WKSITVVYEDSTGLMRMQELIKAPSRNGMKVRIRQLPIGS-SDARPLLKEMKKEQEF-YVIFDCSNQMASELLKQLMSMGMMTEYYHFFFTTLDLFALDLEPYRYSG-VNMTAFRL--------LKLDDPYVGSIVQKWSTERQLSPPRPESGLMIGMMNTAAALMYDAVFMVAVASQRASQMT---VSSLQCHRHKPWRYGPRFMNLFKEA-QWDGLTGRIILNKTDGLRKDFDLDLISLKEDGTAKIGVWNSYSGLNLTEKKENNKNVTDSLANRTLIVTTILENPYVMYKKSDKVLYGNDR----FEGYCLDLLKELSNILGFNYEVKLVTDGKYGAQNDKG-------EWNGMVRELIDHIADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLTPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNASSDVMENNFTLLNSLWFGVAALMRQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMDAPIDSADDLAKQTRIEYGAVRDGSTMTFFKKSKISTYEKMWTFMSSRKNTALVKNTREGITRVLTTD--YALLMESTSIEYISQRNCNLTQVGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEE-DNKEASAL 814          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Cavefish
Match: grik1b (glutamate receptor ionotropic, kainate 1 [Source:NCBI gene;Acc:103021580])

HSP 1 Score: 414.461 bits (1064), Expect = 1.364e-129
Identity = 274/811 (33.79%), Postives = 444/811 (54.75%), Query Frame = 3
Query:  177 LTIGVIFEA--NDDVSRKVVSV--AVQNAN-SQLMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLL---NQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLV--DLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLME----NIFESRKLSKKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNE-EAQRKQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKSPVTETNEVI--KPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCD-DNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNPD-VMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKGSI 2552
            L IG IFE   N+ VS + ++   AV N N ++ +  N +     + ++   SF   R+AC+ L  G+ A+  P        + S  N   +PH+ T+ + P         I L+P+    +  + + I Q   W  + ++++    +++ + L+   +++    K+RQ   G  K  +  L+++   +K K F V  D  Y    D L  + +  +    + F FT  D   LDL  ++ +  VN+T F L+N          +  + +++E       ++ +  +    +  +    A++ D++ ++     R  ++       ++C  +  W  G S F ++       GLTG+I  N+ +  RK+++L ++ L E+G  K G WN N  +      +   T   + +  + L VTTI+  P+V YK +   +  +D     + G+C+DLL E+   L  ++ + LV D KYG   D         +WNGM+ ELI   ADL VAP+TI+Y REKV+DF+ PFM+LG+SIL+  P    PG+FSFL+PLSP +W+YV+ A +GVS +++ I+  TPYEW   HPC+ D+   +N F ++NS+WF V ALM+QG E  P+A STR+V   WWFFTLIIIS+YTANLAAFLTVE++  PI S +DL  Q  I+YG ++ G++  FF+++ I TY+KM  +M +  +  +V++  EG+ +VL ++  YA L+ES   +Y  +R C L ++G ++DSKGYG+G P GSP RDK+T +IL+LQ+  KL  +  KWW      E  D+KE  ++
Sbjct:   22 LRIGGIFETLENEPVSVEELAFKFAVTNINRNRTLMPNTTLTYDIQRINLFDSFEASRRACDQLGLGVAAVFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDSFYINLHPDYAPISRAVLE-IVQFYKWKTVTVVYEDATGLIRLQELIKAPSRYSIKIKIRQLPVGS-KDARPLLKEM---KKGKEFCVIFDCSYQTSADVLKQLLSMGMMTEYYHFFFTTLDLYALDLEPYRYSG-VNMTGFRLLN--------VDNPEVATVLEKWSVERLQAPQKPESGLTDGMMTTEAALMYDAVYMVAAAAQRASQIT---VSSLQCHRHKPWRFG-SRFISMFKEAQWNGLTGQITLNKTDGLRKEFDLDIISLKEDGMEKIGVWNTNLGLNLTDSVRDKTTNVTDSMANRTLIVTTILENPYVMYKKSDKPLYGNDR----FEGYCLDLLKELSNILGFSYEVKLVSDGKYGAQNDKG-------EWNGMVRELIDHVADLAVAPLTITYVREKVIDFSKPFMTLGISILYHKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTLINSVWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMDSPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRKNTALVKNNREGIQRVLTTD--YALLMESTSIEYISQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKVTIAILQLQEEGKLHMMKEKWWRGNGCPEE-DSKEASAL 800          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Cavefish
Match: grik1b (glutamate receptor ionotropic, kainate 1 [Source:NCBI gene;Acc:103021580])

HSP 1 Score: 412.149 bits (1058), Expect = 5.171e-129
Identity = 260/759 (34.26%), Postives = 419/759 (55.20%), Query Frame = 3
Query:  318 SFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLL---NQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLV--DLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMEN----IFESRKLSKKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNE-EAQRKQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKSPVTETNEVI--KPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCD-DNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNPD-VMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKGSI 2552
            SF   R+AC+ L  G+ A+  P        + S  N   +PH+ T+ + P         I L+P+    +  + + I Q   W  + ++++    +++ + L+   +++    K+RQ   G  K  +  L+++   +K K F V  D  Y    D L  + +  +    + F FT  D   LDL  ++ +  VN+T F L+N          +  + +++E       ++ +  +    +  +    A++ D++ ++     R  ++       ++C  +  W  G S F ++       GLTG+I  N+ +  RK+++L ++ L E+G  K G WN N  +      +   T   + +  + L VTTI+  P+V YK +   +  +D     + G+C+DLL E+   L  ++ + LV D KYG   D         +WNGM+ ELI   ADL VAP+TI+Y REKV+DF+ PFM+LG+SIL+  P    PG+FSFL+PLSP +W+YV+ A +GVS +++ I+  TPYEW   HPC+ D+   +N F ++NS+WF V ALM+QG E  P+A STR+V   WWFFTLIIIS+YTANLAAFLTVE++  PI S +DL  Q  I+YG ++ G++  FF+++ I TY+KM  +M +  +  +V++  EG+ +VL ++  YA L+ES   +Y  +R C L ++G ++DSKGYG+G P GSP RDK+T +IL+LQ+  KL  +  KWW      E  D+KE  ++
Sbjct:   34 SFEASRRACDQLGLGVAAVFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDSFYINLHPDYAPISRAVLE-IVQFYKWKTVTVVYEDATGLIRLQELIKAPSRYSIKIKIRQLPVGS-KDARPLLKEM---KKGKEFCVIFDCSYQTSADVLKQLLSMGMMTEYYHFFFTTLDLYALDLEPYRYSG-VNMTGFRLLN--------VDNPEVATVLEKWSVERLQAPQKPESGLTDGMMTTEAALMYDAVYMVAAAAQRASQIT---VSSLQCHRHKPWRFG-SRFISMFKEAQWNGLTGQITLNKTDGLRKEFDLDIISLKEDGMEKIGVWNTNLGLNLTDSVRDKTTNVTDSMANRTLIVTTILENPYVMYKKSDKPLYGNDR----FEGYCLDLLKELSNILGFSYEVKLVSDGKYGAQNDKG-------EWNGMVRELIDHVADLAVAPLTITYVREKVIDFSKPFMTLGISILYHKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTLINSVWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMDSPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRKNTALVKNNREGIQRVLTTD--YALLMESTSIEYISQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKVTIAILQLQEEGKLHMMKEKWWRGNGCPEE-DSKEASAL 760          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Sea Lamprey
Match: gria1b (glutamate receptor, ionotropic, AMPA 1b [Source:ZFIN;Acc:ZDB-GENE-020125-2])

HSP 1 Score: 318.931 bits (816), Expect = 4.163e-98
Identity = 188/440 (42.73%), Postives = 261/440 (59.32%), Query Frame = 3
Query: 1287 GYWN--GNNFVI----FPPKSKSPVTETNEVIKPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCD---------------------------DNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMEN-NPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERE-CTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWW 2501
            GYW+    N VI       ++ S  T    VI    VTTI+  P+   K N    + +D     + G+C+DL  EI    +  +   +V D  YG       NPD ++ WNGM+GEL+   AD+ +AP+TIS  RE+V+DF+ PFMSLG+SI+   PQK  PG+ SFL PL+  +W+ +I AYIGVS++++ +S  +PYEW +    D                             G   N+F I NSLWF++ A M+QG E  P++ S R+V   WWFFTLIIIS+YTANLAAFLTVE++V PI+S +DL  Q  I YGTL  G+++ FF+R+ I  Y+KM  +M++  P V VR+  +GV +V KS GKYA+LLES  N+Y ++R+ C  ++VG  LDSKGYGI  P GS LRD +  ++LKL +   L  L +KWW
Sbjct:    3 GYWSERARNLVITNQEMLGRNGSGKTGNRTVI----VTTILDAPYFMLKKNHEQFEGNDK----YEGYCVDLGQEIAIHEQFEYKWSVVPDGAYGA-----RNPD-TKVWNGMVGELVYGRADIAIAPLTISLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVISFLDPLAYEIWMCIIFAYIGVSVVLFLVSRFSPYEWQRDDDTDVEPNGNGGAGGGGGGGGSGGGAGGGSGGGGEPPNEFGIFNSLWFSLGAFMQQGCEISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESADDLAKQTEIAYGTLDSGSTKEFFQRSKIGVYEKMWLFMKDAEPKVFVRTNADGVSRVRKSKGKYAYLLESTTNEYTEQRKPCDTMKVGGNLDSKGYGIATPKGSALRDAVNLAVLKLNEQGLLDKLKNKWW 428          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005084.1 (pep scaffold:Pmarinus_7.0:GL476900:54926:87395:-1 gene:ENSPMAG00000004612.1 transcript:ENSPMAT00000005084.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 287.73 bits (735), Expect = 3.478e-89
Identity = 148/292 (50.68%), Postives = 211/292 (72.26%), Query Frame = 3
Query: 1629 EADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCD-DNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWW 2501
            +ADL VAP+TI+Y REK +DF+ PFM+LG+SIL+  P    PG+FSFL+PLSP +W+Y++ AY+GVS +++ I+  +PYEW   HPC+ D+   +N F +LNS WF V ALM+QG E  P+A STR+V   WWFFTLIIIS+YTANLAAFLTVE++  PI S +DL  Q  I+YG ++ G++  FF+++ I TY+KM  +M +    ++++ EEG+ +VL ++  YA L+ES   +Y  +R C L ++G ++D+KGYGIG P GSP RDK+T +IL+LQ+  KL  +  KWW
Sbjct:    9 KADLAVAPLTINYMREKAIDFSKPFMTLGISILYRKPNGTNPGIFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPHPCNPDSDVVENNFTMLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPISSADDLAKQTRIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQTALIKNNEEGIQRVLTTD--YAMLMESTNIEYVTQRNCNLTQIGGLIDNKGYGIGTPLGSPYRDKITIAILQLQEEGKLHMMKEKWW 298          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002503.1 (pep scaffold:Pmarinus_7.0:GL492163:1:1446:1 gene:ENSPMAG00000002286.1 transcript:ENSPMAT00000002503.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 191.815 bits (486), Expect = 2.336e-56
Identity = 90/189 (47.62%), Postives = 132/189 (69.84%), Query Frame = 3
Query: 1857 TPYEWLQIHPCD-DNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMEN-NPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTG 2417
            +PYEW   HPC+ D+   +N F +LNSLWF V ALM+QG E  P+A STR+V   WWFFTLI+IS+YTANLAAFLTVE++  PI S +DL  Q  I+YG ++ G++  FF+++ I TY+KM  +M + +   +V++ EEG+ + L ++  +A L+ES   ++  +R C L ++G ++DSKGYG+G P G
Sbjct:    2 SPYEWKNPHPCNPDSDVLENNFTMLNSLWFGVGALMQQGSELMPRALSTRIVGGIWWFFTLILISSYTANLAAFLTVERMESPIGSADDLAKQTKIEYGAVRDGSTMTFFKKSRISTYEKMWAFMSSRHQTALVKNNEEGIHRALTTD--FAMLMESTTIEHVTQRYCNLTQIGGLIDSKGYGVGMPLG 188          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010716.1 (pep scaffold:Pmarinus_7.0:GL476465:413535:454465:1 gene:ENSPMAG00000009705.1 transcript:ENSPMAT00000010716.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 125.561 bits (314), Expect = 1.213e-29
Identity = 96/332 (28.92%), Postives = 169/332 (50.90%), Query Frame = 3
Query: 1467 GFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAP-GXXXXXXXXXXXVWVYVISAYIGVSLIIYFI-SHVTPYEW-LQIHPCDDNGSRQNQFNILNSLWFTVAALMRQGLEF-CPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVED------LVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYY--KERECTLIRVGD--MLDSKGYGIGFPTGS 2420
            GFCID+L ++   ++  + ++LV + K+G+ ++          WNGMIGE+++  A + V  +TI+ ER +VVDF+ PF+  G+S+  + P+        +FL P S  VWV +    + VS I  FI  + +P  +  Q+    + G     F I  S+W   A +    +    P+ ++++ + S W FF +I +++YTANLAAF+  E  +  +  + D      L +    ++GT+  G++    ER +   Y +MH YM        +S E+ +   LK+    AF+ ++A+ +Y   K+  C L+ +G   +  + GYGI     S
Sbjct:  398 GFCIDILKKLSKTVKFTYDLYLVTNGKHGSKING--------VWNGMIGEVVNMRAHMAVGSLTINEERSEVVDFSVPFVETGISV--MVPRSNGTVSPSAFLEPFSADVWVMMFILCLLVSGIAVFIFEYFSPVGYNRQLSAGKEFGGP--AFTIGKSIWLLWAIVFNNSVPVENPRGTTSKFMVSVWAFFAVIFLASYTANLAAFMIQEDYIDQVSGLSDKKFQSPLEHSPPFRFGTVPNGST----ERNIRNNYLQMHGYMSK---FHQKSVEDAL-MSLKAGKLDAFIYDAAVLNYMAGKDEGCRLVTIGSGKVFVATGYGIALQKSS 709          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007790.1 (pep scaffold:Pmarinus_7.0:GL476616:796957:798868:-1 gene:ENSPMAG00000007047.1 transcript:ENSPMAT00000007790.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 114.775 bits (286), Expect = 1.619e-27
Identity = 77/257 (29.96%), Postives = 136/257 (52.92%), Query Frame = 3
Query: 1674 EKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCDDNGSRQNQ-FNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMT 2441
            ++ +  + P +  G  I+    +   P +F FL PL+ L+W+ ++SA  G+S++++ +S + P EW  +         Q Q FN++NS WF  +A+++QG +  P + + +++   WW F L++ STYTANLAAFLT E     I+S++DL  Q   +YGT  G     F   +    Y  + +++ +N   MV S ++G+++  K+   Y F+ E++     K+  C LI            + FP GS L  +++
Sbjct:    1 DERLALSPPILENGYHIIMKGKEVNEPRIFQFLEPLNTLLWISMLSACAGISVVLFVLSLLHPDEWYHLAKRKLVSREQGQSFNLVNSFWFVFSAMVKQGSDPLPLSMAGKIIVYTWWCFVLVVCSTYTANLAAFLTAEGQT-SIRSLKDLTRQMDARYGTYSGYRIVGFLNSSARDPYMTVWRHIRDN-RTMVASPKKGLEQAEKAG--YIFIGEASAVFTAKKDHCDLIISDRRFFRHRLALPFPPGSRLAAEVS 253          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Nematostella
Match: EDO41291 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4J5])

HSP 1 Score: 204.142 bits (518), Expect = 9.926e-58
Identity = 129/395 (32.66%), Postives = 224/395 (56.71%), Query Frame = 3
Query: 1398 PFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCDDNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQ-IVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERE-CTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTK-EKGSIPTALDVH 2573
            PF+  K N+  +K +D     + GF  DL+  +   L   + I + K++ YG+ V+ +        W G+IGEL+ +EAD+ + P+TI+ ERE+V+DF+ PF+   ++++   P  E   LF+FL P    +W+  +     VSLI++F+   +P  + +           ++F++ NSLWF VA++++QG +  P+++S R++++A+W FTLI+ISTYTANLAA+ T E+ I   I S+EDLV+Q T+KYG  +GG+   FF  + +  Y  M + M++  +  V  T+ GV K       +A+L +    DYY  R+ C  + V ++LD+K Y +     S   + ++ +IL+L++  ++     +WW++   +  C T     S P  L++H
Sbjct:   10 PFMMIKPNASLLKGNDR----YRGFSKDLMELLSRKLNFRYEICISKESSYGSKVEGQ--------WQGLIGELVREEADIALGPITITAEREEVIDFSKPFLDFRIAMILQQPTGEEVNLFAFLLPFDEKLWLTTLGVVGLVSLIVWFLDRFSPQGY-KTQAEKSGEGEGDEFSLSNSLWFAVASILQQGGDNTPRSTSGRVLAAAFWLFTLILISTYTANLAAYFTGERGIRSKINSLEDLVSQSTVKYGVQEGGSLFTFFSESKVDIYATMFQQMKSQ-ETFVNGTQYGVLKA--RTQPFAYLTDQPSLDYYNMRKPCNTMLVKNLLDAKSYALAMRRNSEWTNLISVAILELREEGEIEKSRLRWWDD---SSECPTGPSTDSSPQRLELH 385          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Nematostella
Match: EDO30203 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T1G4])

HSP 1 Score: 210.305 bits (534), Expect = 2.243e-56
Identity = 141/453 (31.13%), Postives = 236/453 (52.10%), Query Frame = 3
Query: 1146 GISLFNAITSVDHMYGLTGRIVFNEEAQRKQYNLSVMELTENGFMKKGYWN--------GNNFVIFPPKSKSPVTETNEVI--KPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQ--IHPCDDNGSRQ-----NQFNILNSLWFTVAALMRQGLEFC-PQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDY--YKEREC-TLIRVGDMLDSKGYGIGFPTGSPLRDKMT 2441
            G +L + I+ V+   G+  ++ F+           V+ L   GF K GYWN            +++P       T++  ++  + L+V TI   PF+F +  +    E    I+   G+CI+LL ++   LR  F ++LV DN +G       +P  +++WNG++ E+++  ADL V  +TIS ER+KV+DFT P+M LGL++L      E    F+ L P    +W+ +    I V   ++  S  +P+ +    +  C      +     +  +++ +LW TV   + Q  +   P +SS R+  + +WF  LI++STYTANLAAFLT+++   PI SV+DL  QK I YGT+     +AFFE A + ++  M +YM  +    V ++ EG++KV+  N  YAF+ +SA+ ++  + +  C TLI  G +    GYG G    SP   +++
Sbjct:  362 GATLLDYISQVNTT-GVMNQLGFDSNRSPVDVAFDVVNLRAFGFQKVGYWNVEEGLHLDNKKEIVWPSGRVYVPTDSTHILENRTLKVVTIAEAPFIFAQTQTNGQGETRVIIE---GYCIELLRKLSEMLRFKFEVYLVPDNNFGA-----QDPV-TKEWNGVVREVLNGRADLAVTSLTISPERQKVIDFTQPYMDLGLTVLIKPDPTEEKNPFAILRPFRYDLWMAIGGTMIIVGFFLWLFSTFSPFGFYGRCVQKCHTKIEPRYLKLHDTLSLVRALWSTVVYYVGQSSDHLHPVSSSGRITVAVYWFAMLIVMSTYTANLAAFLTIKRFTSPISSVDDLARQKDISYGTVLNSQPQAFFESASVPSFVTMWQYMRYH-HTFVNNSAEGIEKVMNEN--YAFIWDSAVLEFVAHNQISCGTLITSGSVFGRIGYGFGLAKDSPYTKQLS 801          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Nematostella
Match: EDO35545 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SL56])

HSP 1 Score: 204.912 bits (520), Expect = 1.429e-54
Identity = 146/487 (29.98%), Postives = 248/487 (50.92%), Query Frame = 3
Query: 1044 DSINVLMEGLIRLIKLQPVFTQP-MKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNEEAQRKQYNLSVMELTEN--------GFMKKGYWNGNNFVIFPPKSKSPVTETNEVIKPLRVTTIVSLPFVFYK---------DNSPDIKEH----DTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCDDNGSRQNQFNILNSLWFTVAALMRQGL-EFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVED--LVN-QKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNPDVMVRSTEEGVDKVLKSNGKY-AFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSP 2423
            D+  +    L  L       T P   C     W+ G  LFNA+ +V    G TG I FN +  RK     +M   ++        G  + G+ + N  +I+P    +  T    +   LRV T+V  PFV+ K         D   +  +H     T  D  +GFC+DLL  +G  +   +S+ L +D  YG++     N   +++WNGM+GE+I  +ADL+VA +TI+ ER + ++F+ PF   GL+IL +   +++  L SFL P    +W+ V+ +   V++I+Y +   +P+   ++   +     +   N+ +++WF+   L+  G+ E  P++ S R++   W  F +II+++YTANLAAFL +++    +  ++D  L N  K   Y T+   + +A+F R +      M+ +ME      V++ +EG++KV   NG+  AF+ +S +  Y   ++CTL   G++    GYGIG P GSP
Sbjct:  279 DATVISATALQNLANAGKTLTTPTASCRETQQWSSGQELFNALVNVSLPRGTTGPIAFNSDGDRKNAVYRLMNRRQSSSDAVDVVGLYENGHVSINESIIWPGNLNTTPTGVF-LSNHLRVVTLVGEPFVYVKPIPTSGRCSDLDTNTAKHVLCTGTVSDTDSGFCMDLLIRLGEKVNFTYSVSLSEDGSYGSL--RRVNGSDTKQWNGMVGEVIQGKADLIVAALTINNERAEWIEFSKPFKYQGLTIL-VKKNEQSNSLDSFLRPFQIHLWLLVLLSVHIVAVILYLLDRFSPFGRFKLARKEK---EETALNLSSAMWFSWGVLLNSGIGEGTPRSFSARVLGMVWAGFAMIIVASYTANLAAFLVLDRPKAVVSGIDDPNLRNPSKQFIYATVANSSVDAYFRRQV--ELSSMYTFMEG---YNVKTAKEGIEKV--KNGELKAFIWDSPVLYYEASKDCTLTTAGELFGRSGYGIGMPKGSP 751          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Nematostella
Match: EDO46633 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPU4])

HSP 1 Score: 180.644 bits (457), Expect = 1.245e-46
Identity = 144/494 (29.15%), Postives = 244/494 (49.39%), Query Frame = 3
Query: 1146 GISLFNAITSVDHMYGLTGRIVFNEEAQRKQYNLSVMELTENGFMKKGYWNGNNFVIFPPK------SKSPVT--ETNEVI--KPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCDDNGSRQNQF-------NILNSLWFTVAALMRQGLEFC-PQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYME----NNPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERE-CTLIRVGDMLDSKG-----YGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEK 2543
            GI+L   I  V    G  G + F+++      ++ ++ + EN F K G WN  + ++          S  P T  ++  V+  + +RV +    PF     N        +S+D + G  IDLL+ +   L  N++I++  D + G  V+N    +    W+G+I ELI + ADL V P+TI+  R KV+DFT PFM+ G+ ++  T     P  F FL P    +W+ +  A +G+ ++ +  S V+P+ +        N   +  +       + LNS+W + A  + QG +   P ++S R   + WWF   I+ +TYTAN+AAFLT  ++  PI+ +EDL +Q  I YG ++   ++ FF+ + +Q Y+ M +YM+      PD     T   +++ LK  GKYAF+ ++ + +Y   +  C  I++    D++      YG   P  SP  + ++  ILKL +S     +I +W  E     P D  E+
Sbjct:  298 GITLNKYIQKV-QTAGFMGFLSFSQDGFLANPSIDIINVKENEFDKVGEWNTKDGLMMDSDKTVVWMSGGPGTPRDSENVLADRTIRVVSFKGSPFTMPVGNV------SSSVDRFEGAVIDLLDRLSEILHFNYTIYMSPDGRVG--VENPVTGN----WDGVINELIQERADLAVGPITITSHRWKVIDFTQPFMTSGIGVVMGTENSPKP-YFRFLEPFKSDLWITIFGAVLGMGVVNWLFSVVSPFGFYGRCVQSINKRVKKSYLKQKYSLSFLNSIWSSAAYYLGQGPDGNHPVSASGRAAVAVWWFVITILGATYTANMAAFLTTTRMQTPIRRIEDLSSQTEIAYGCVENSLTQNFFQSSSVQRYQMMWEYMKLRRSLQPD-----TYTAIERTLK--GKYAFIHDAPILEYLARKTYCGRIKLIGGYDTRTFGNAHYGFALPKKSPYTNLLSVEILKLVQSGIAKTMIEEWMIERTPCAPLDEAEE 770          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Nematostella
Match: EDO41293 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4J7])

HSP 1 Score: 145.976 bits (367), Expect = 7.615e-39
Identity = 83/265 (31.32%), Postives = 155/265 (58.49%), Query Frame = 3
Query: 1791 VWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCDDNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERE-CTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEK--GSIPTALDVHQ 2576
            +W         V+++++ +   +PY + +    +      ++F++ NSLWF   ++++QG +  P++ S R++++++W FTLI+ISTYTANLAAF T +     I S+EDLV Q   KYG  +GG+  +FFE++ ++ YKKM   M +  +  V+ T+EGV++       +A+L +    DYY +R+ C  + V ++LD+K Y +G    S   D ++ +IL+L++  ++  + +KWW+  +    C+ K+    + P +L++H 
Sbjct:   12 LWACCCLVVGAVTILMWILDRFSPYGF-RAEAKNTGEGEGDEFSLPNSLWFATGSILQQGGDNTPRSGSGRVLAASFWLFTLILISTYTANLAAFFTAQNSKSTINSLEDLVAQDVFKYGVQQGGSLFSFFEKSKVRIYKKMFGKM-STLNTFVKGTDEGVNR--SRTTPFAYLTDQPSLDYYNQRKPCNTMLVKNLLDAKSYALGLQRNSEWTDGISVAILQLREEGEVERIRYKWWDAMS---ECNLKDAVVSNQPMSLELHH 269          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Medaka
Match: grik1a (glutamate receptor ionotropic, kainate 1 [Source:NCBI gene;Acc:101173326])

HSP 1 Score: 421.394 bits (1082), Expect = 4.819e-132
Identity = 275/811 (33.91%), Postives = 436/811 (53.76%), Query Frame = 3
Query:  171 IYLTIGVIFEANDD----VSRKVVSVAVQNAN-SQLMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLLN---QFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLV--DLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLIN--DSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNE-EAQRKQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKSPVTETNEVI--KPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCDDNGSR-QNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNPD-VMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKGSI 2552
            +YL  G IFE  +     +       AV N N ++ +  N +     + ++    F   R+ C+ L  G+VA+  P        + S  N   +PH+ T+ + P  +      I LYP   A A  I   +T  + W ++ +I++    +M+ + L+    +     K+RQ   G+ +  +  L++L   +K K F +  D  Y    + L+ +S+  +    + F FT  D   LDL  ++ +  VN+T   L+N  D LV S  ++       M+ +   ++   K  I   +    A++ D++ ++     R  ++       ++C  +  W  G    N         GLTGRIV ++ +  RK ++L V+ L E+G  +   WN    +     ++   +   + +  + L VTTI+  P+V  + +  ++  +D     + G+C+DLL E+   L   + + LV D KYG   D         +WNGM+ ELI   ADL VAP+TI+Y REKV+DF+ PFM+LG+SIL+  P    PG+FSFL+PLSP +W+YV+ A  GVS +++ I+  TPYEW   HPC+ + +  QN F +LNS WF + ALMRQG E  P+A STR+V   WWFFTLIIIS+YTANLAAFLTVE++  PI S +DL  Q  I+YG ++ G++  FF+++ I TY+KM  +M +  +  +V++ +EG+ +VL ++  YA L+ES   +Y  +R C L ++G ++DSKGYG+G P GSP RDK+T +IL+LQ+  KL  +  KWW      E  D KE  ++
Sbjct:    5 LYLCTGGIFETRESELVSMDELAFKFAVNNINRNKTLMPNSTLTYDIQRINIFDGFEASRRVCDQLALGVVAVFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVNNKDTFFINLYPEYTAIARAILDVVTFFK-WKKLTVIYEDSTGLMRMQELIKAPAKLNLKIKIRQLTPGN-QDARPLLKEL---KKDKEFFIIFDCSYRMASELLMQLSSMGMMTEYYHFFFTTLDLFALDLEPYRYSG-VNMTGLRLLNFDDPLVASTMSKWA-----MDRMQGPKQ--DKGLIEGVMTTDAALMYDAVYMVAIAAQRATQMT---VSSLQCHRHKPWRFGPRFMNLFKEA-QWNGLTGRIVLSKTDGLRKDFDLDVISLQEDGTARVAIWNSYKGMTLIESNRDKNSNVTDSLANRTLIVTTILENPYVMVRKSDKELVGNDR----YEGYCMDLLKELSNILGFTYEVRLVGDGKYGAQNDKG-------EWNGMVRELIEHVADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACTGVSCVLFVIARFTPYEWYNPHPCNPSSTLVQNNFTLLNSFWFGIGALMRQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMDAPIDSADDLAKQSRIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRKNTALVKNNKEGITRVLTTD--YAMLMESTSIEYISQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKVTIAILQLQEEGKLHMMKEKWWRGNGCPEE-DNKEASAL 784          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Medaka
Match: grik1b (glutamate ionotropic receptor kainate type subunit 1 [Source:NCBI gene;Acc:101173645])

HSP 1 Score: 417.927 bits (1073), Expect = 8.103e-131
Identity = 277/809 (34.24%), Postives = 443/809 (54.76%), Query Frame = 3
Query:  177 LTIGVIFEA--NDDVSRKVVSV--AVQNAN-SQLMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLL---NQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLV--DLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLIN--DSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNE-EAQRKQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKSPVTETNEVI--KPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCD-DNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNPD-VMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKGSI 2552
            L IG IFE   N+ +S + ++   AV N N ++ +  N +     + ++   SF   R+AC+ L  G+ A+  P        + S  N   +PH+ T+ + P         I L+P   + +  +   I Q   W  + ++++    +++ + L+   +++    K+RQ   G  K  +  L+++   +K K F V  D  Y    D L  + +  +    + + FT  D   LDL  ++ +  VN+T F L+N  D  V+ +  R       ME +    K+ +   +   +    A++ D++ ++     R  ++       ++C  +  W  G    N +       GLTG+I+ N+ +  RK+++L V+ L E+G  K G WN    +     S+   T   + +  + L VTTI+  P+V YK +   +  +D     + G+C+DLL E+   L  ++ + LV D KYG   D         +WNGM+ ELI   ADL VAP+TI+Y REKV+DF+ PFM+LG+SIL+  P    PG+FSFL+PLSP +W+YV+ A +GVS +++ I+  TPYEW   HPC+ D+   +N F ++NS+WF V ALM+QG E  P+A STR+V   WWFFTLIIIS+YTANLAAFLTVE++  PI S +DL  Q  I+YG ++ G++  FF+++ I TY+KM  +M +  +  +V++  EG+ +VL ++  YA L+ES   +Y  +R C L ++G ++DSKGYG+G P GSP RDK+T +IL+LQ+  KL  +  KWW      E  D+KE  ++
Sbjct:   26 LRIGGIFETLENEPISVEELAFKFAVTNINRNRTLMPNTTLTYDIQRINLFDSFEASRRACDQLALGVGAVFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDSFYINLHPEYASLSRAVLD-IVQFYKWKAVTVVYEDATGLIRLQELIKAPSRYSIKIKIRQLPSGT-KDARPLLKEM---KKGKEFFVIFDCSYQTTTDVLKQILSMGMMTEYYHYFFTTLDLFSLDLEPYRYSG-VNMTGFRLLNVDDPKVSLVLERWA-----MERLQAPSKV-ETGMMEGMMTTEAALMYDAVYMVAAASQRTSQIT---VSSLQCHRHKPWRFGSRFINLLKDT-QWSGLTGQILINKTDGLRKEFDLDVISLKEDGLEKIGVWNSQMGLNLTETSRDSSTNITDSMANRTLVVTTILENPYVMYKKSDKPLYGNDR----FEGYCLDLLKELSNILGFSYEVKLVSDGKYGAQNDKG-------EWNGMVRELIDHVADLAVAPLTITYVREKVIDFSKPFMTLGISILYHKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTLINSVWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMDSPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRKNTALVKNNREGIQRVLTTD--YALLMESTSIEYISQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKVTIAILQLQEEGKLHMMKEKWWRGNGCPEE-DSKEASAL 804          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Medaka
Match: grik1a (glutamate receptor ionotropic, kainate 1 [Source:NCBI gene;Acc:101173326])

HSP 1 Score: 417.542 bits (1072), Expect = 8.119e-131
Identity = 264/757 (34.87%), Postives = 415/757 (54.82%), Query Frame = 3
Query:  318 SFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLLN---QFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLV--DLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLIN--DSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNE-EAQRKQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKSPVTETNEVI--KPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCDDNGSR-QNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNPD-VMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKGSI 2552
             F   R+ C+ L  G+VA+  P        + S  N   +PH+ T+ + P  +      I LYP   A A  I   +T  + W ++ +I++    +M+ + L+    +     K+RQ   G+ +  +  L++L   +K K F +  D  Y    + L+ +S+  +    + F FT  D   LDL  ++ +  VN+T   L+N  D LV S  ++       M+ +   ++   K  I   +    A++ D++ ++     R  ++       ++C  +  W  G    N         GLTGRIV ++ +  RK ++L V+ L E+G  +   WN    +     ++   +   + +  + L VTTI+  P+V  + +  ++  +D     + G+C+DLL E+   L   + + LV D KYG   D         +WNGM+ ELI   ADL VAP+TI+Y REKV+DF+ PFM+LG+SIL+  P    PG+FSFL+PLSP +W+YV+ A  GVS +++ I+  TPYEW   HPC+ + +  QN F +LNS WF + ALMRQG E  P+A STR+V   WWFFTLIIIS+YTANLAAFLTVE++  PI S +DL  Q  I+YG ++ G++  FF+++ I TY+KM  +M +  +  +V++ +EG+ +VL ++  YA L+ES   +Y  +R C L ++G ++DSKGYG+G P GSP RDK+T +IL+LQ+  KL  +  KWW      E  D KE  ++
Sbjct:   37 GFEASRRVCDQLALGVVAVFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVNNKDTFFINLYPEYTAIARAILDVVTFFK-WKKLTVIYEDSTGLMRMQELIKAPAKLNLKIKIRQLTPGN-QDARPLLKEL---KKDKEFFIIFDCSYRMASELLMQLSSMGMMTEYYHFFFTTLDLFALDLEPYRYSG-VNMTGLRLLNFDDPLVASTMSKWA-----MDRMQGPKQ--DKGLIEGVMTTDAALMYDAVYMVAIAAQRATQMT---VSSLQCHRHKPWRFGPRFMNLFKEA-QWNGLTGRIVLSKTDGLRKDFDLDVISLQEDGTARVAIWNSYKGMTLIESNRDKNSNVTDSLANRTLIVTTILENPYVMVRKSDKELVGNDR----YEGYCMDLLKELSNILGFTYEVRLVGDGKYGAQNDKG-------EWNGMVRELIEHVADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACTGVSCVLFVIARFTPYEWYNPHPCNPSSTLVQNNFTLLNSFWFGIGALMRQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMDAPIDSADDLAKQSRIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRKNTALVKNNKEGITRVLTTD--YAMLMESTSIEYISQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKVTIAILQLQEEGKLHMMKEKWWRGNGCPEE-DNKEASAL 762          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Medaka
Match: grik1a (glutamate receptor ionotropic, kainate 1 [Source:NCBI gene;Acc:101173326])

HSP 1 Score: 417.157 bits (1071), Expect = 1.353e-130
Identity = 264/757 (34.87%), Postives = 415/757 (54.82%), Query Frame = 3
Query:  318 SFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLLN---QFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLV--DLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLIN--DSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNE-EAQRKQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKSPVTETNEVI--KPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCDDNGSR-QNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNPD-VMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKGSI 2552
             F   R+ C+ L  G+VA+  P        + S  N   +PH+ T+ + P  +      I LYP   A A  I   +T  + W ++ +I++    +M+ + L+    +     K+RQ   G+ +  +  L++L   +K K F +  D  Y    + L+ +S+  +    + F FT  D   LDL  ++ +  VN+T   L+N  D LV S  ++       M+ +   ++   K  I   +    A++ D++ ++     R  ++       ++C  +  W  G    N         GLTGRIV ++ +  RK ++L V+ L E+G  +   WN    +     ++   +   + +  + L VTTI+  P+V  + +  ++  +D     + G+C+DLL E+   L   + + LV D KYG   D         +WNGM+ ELI   ADL VAP+TI+Y REKV+DF+ PFM+LG+SIL+  P    PG+FSFL+PLSP +W+YV+ A  GVS +++ I+  TPYEW   HPC+ + +  QN F +LNS WF + ALMRQG E  P+A STR+V   WWFFTLIIIS+YTANLAAFLTVE++  PI S +DL  Q  I+YG ++ G++  FF+++ I TY+KM  +M +  +  +V++ +EG+ +VL ++  YA L+ES   +Y  +R C L ++G ++DSKGYG+G P GSP RDK+T +IL+LQ+  KL  +  KWW      E  D KE  ++
Sbjct:   37 GFEASRRVCDQLALGVVAVFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVNNKDTFFINLYPEYTAIARAILDVVTFFK-WKKLTVIYEDSTGLMRMQELIKAPAKLNLKIKIRQLTPGN-QDARPLLKEL---KKDKEFFIIFDCSYRMASELLMQLSSMGMMTEYYHFFFTTLDLFALDLEPYRYSG-VNMTGLRLLNFDDPLVASTMSKWA-----MDRMQGPKQ--DKGLIEGVMTTDAALMYDAVYMVAIAAQRATQMT---VSSLQCHRHKPWRFGPRFMNLFKEA-QWNGLTGRIVLSKTDGLRKDFDLDVISLQEDGTARVAIWNSYKGMTLIESNRDKNSNVTDSLANRTLIVTTILENPYVMVRKSDKELVGNDR----YEGYCMDLLKELSNILGFTYEVRLVGDGKYGAQNDKG-------EWNGMVRELIEHVADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACTGVSCVLFVIARFTPYEWYNPHPCNPSSTLVQNNFTLLNSFWFGIGALMRQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMDAPIDSADDLAKQSRIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRKNTALVKNNKEGITRVLTTD--YAMLMESTSIEYISQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKVTIAILQLQEEGKLHMMKEKWWRGNGCPEE-DNKEASAL 762          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Medaka
Match: grik5 (glutamate ionotropic receptor kainate type subunit 5 [Source:NCBI gene;Acc:101174774])

HSP 1 Score: 422.165 bits (1084), Expect = 2.978e-130
Identity = 276/787 (35.07%), Postives = 423/787 (53.75%), Query Frame = 3
Query:  219 RKVVSVAVQNANSQLMRYNYSFRIVTE--TVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRH-LSSFSNRFHIPHLVTKCQFPESSASYP----MNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLLNQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFES-RKLSKKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNEEAQRKQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKSPVTETNEVIKPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPC--DDNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYM-ENNPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKG 2546
            R  +++A +N NS +M      R+  +   +  +  +      C +L  G+V++I P S   S   +S       IPH+      PE +   P     ++ LYP+ +  +  I   +         ++  K++ C+++ E L+ +F    +       D   +   L K  +  K    ++D         L   S   +T   + +I T  D  +L L    ++ + NI  FS+ N        T H      + ++  S R+    ++    L  + A++ D+++V++  +  L + Q +  +P+ CT+   W  G SL N +  V++  GLTGR+ FN + QR  Y L ++E    G  + G W  NN +     S           K L VTTI+  P+V  KDN  D + +D     + GFC+D+L E+   L+ +F I LV D  YG        P+GS  W GM+GELI+++ADL VA  TI+ EREKV+DF+ PFM+LG+SIL+       PG FSFL P SP VW++++ AY+ VS +++  + ++PYEW   HPC  +     +NQ+ + NSLWF V   M+QG E  P+A STR VS  WW FTLIIIS+YTANLAAFLTV+++  PI+S +DL +Q  I+YGT+ GG++  FF  +  QTY++M  YM    P V V+STEEG+ +VL  N KYAFL+ES MN+Y++   C L ++G +LD+KGYGIG P GSP RD++T +IL+LQ++ +L  L  +WW      +  D + KG
Sbjct:   51 RLALALARENINS-VMEGPARARVEVDIYELQKDSQYDTTDTMCQILPKGVVSVIGPASSPASGSTVSHICGEKEIPHVKIG---PEETPRLPYLRFASVTLYPSNEDLSLAIGAILRSFSYPSASLVCAKAE-CLLRLEELVRRFLISRETLSVRMLDDNLDPTPLLKEIRDDKVATIIIDANASVSYLILKKASELGMTSAFYKYILTTMDFPLLRLDDI-VDEQSNIVGFSMFN--------TTHPFYLEFIRSLNLSWREGCDLTYPGPAL--SSALMFDAVHVVVGAVRELNRSQEIGVKPLSCTSPQIWQHGTSLMNYLRMVEY-DGLTGRVEFNSKGQRTNYTLRILEKHRGGHKEIGIWYSNNTLAMNSTSLDINVSETLANKTLIVTTILENPYVMRKDNYQDFQGNDQ----YEGFCVDMLRELADILKFSFKIKLVDDGLYGA-----PEPNGS--WTGMVGELINRKADLAVAAFTITSEREKVIDFSKPFMTLGISILYRVQLGRKPGYFSFLDPFSPAVWLFMLLAYLAVSCVLFLAARLSPYEWYNPHPCMRERRDMLENQYTLGNSLWFPVGGFMQQGSEIMPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEAPIESPDDLADQTNIEYGTIHGGSTMTFFMNSRYQTYQRMWNYMYSKQPSVFVKSTEEGIARVL--NSKYAFLMESTMNEYHRGLNCNLTQIGGLLDTKGYGIGMPLGSPFRDEITLAILQLQENNRLEILKRRWWEGSQCLKEEDHRAKG 807          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Planmine SMEST
Match: SMESG000005192.1 (SMESG000005192.1)

HSP 1 Score: 1722.6 bits (4460), Expect = 0.000e+0
Identity = 884/902 (98.00%), Postives = 885/902 (98.12%), Query Frame = 3
Query:   93 MMPTISSFPFLLMLLGRPILSKELSKIYLTIGVIFEANDDVSRKVVSVAVQNANSQLMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLLNQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNEEAQRKQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKSPVTETNEVIKPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCDDNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKGSIPTALDVHQXXXXXXXXXXXXXXASMVSVIELYVTYCEGTCKWNVPFHIYFQKELQFAVRFMSSSKKPLNTYNVDNKSREDCL 2798
            MMPTISSFPFLLMLLGRPILSKELSKIYLTIGVIFEANDDVSRKVVSVAVQNANSQLMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLLNQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDH+               KQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKSPVTETNEVIKPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGLFSFLSPLSPLVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCDDNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTKSILKLQKSQKLSNLIHKWWNEFNITEPCDTKEKGSIPTALDVHQVGGVFLLLGVGFIFASMVSVIELYVTYCEGTCKWNVPFHIYFQKELQFAVRFMSSSKKPLNTYNVDNKSRE  L
Sbjct:    1 MMPTISSFPFLLMLLGRPILSKELSKIYLTIGVIFEANDDVSRKVVSVAVQNANSQLMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLLNQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHI---------------KQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKSPVTETNEVIKPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGLFSFLSPLSPLVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCDDNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTKSILKLQKSQKLSNLIHKWWNEFNITEPCDTKEKGSIPTALDVHQVGGVFLLLGVGFIFASMVSVIELYVTYCEGTCKWNVPFHIYFQKELQFAVRFMSSSKKPLNTYNVDNKSRERLL 887          

HSP 2 Score: 153.68 bits (387), Expect = 1.034e-37
Identity = 72/73 (98.63%), Postives = 72/73 (98.63%), Query Frame = 2
Query: 2789 RLLILDYKQENYNAPSNRTSLHLHNPSKTSRNYPTPTNTPRIFTELDESCNDDKNCLNISHDSLESISNMCGV 3007
            RLLILDYKQENYNAPSNRTSLHLHNPSKTSRNYPT TNTPRIFTELDESCNDDKNCLNISHDSLESISNMCGV
Sbjct:  885 RLLILDYKQENYNAPSNRTSLHLHNPSKTSRNYPTTTNTPRIFTELDESCNDDKNCLNISHDSLESISNMCGV 957          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Planmine SMEST
Match: SMESG000005192.1 (SMESG000005192.1)

HSP 1 Score: 1720.67 bits (4455), Expect = 0.000e+0
Identity = 883/901 (98.00%), Postives = 884/901 (98.11%), Query Frame = 3
Query:   96 MPTISSFPFLLMLLGRPILSKELSKIYLTIGVIFEANDDVSRKVVSVAVQNANSQLMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLLNQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNEEAQRKQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKSPVTETNEVIKPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCDDNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKGSIPTALDVHQXXXXXXXXXXXXXXASMVSVIELYVTYCEGTCKWNVPFHIYFQKELQFAVRFMSSSKKPLNTYNVDNKSREDCL 2798
            MPTISSFPFLLMLLGRPILSKELSKIYLTIGVIFEANDDVSRKVVSVAVQNANSQLMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLLNQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDH+               KQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKSPVTETNEVIKPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGLFSFLSPLSPLVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCDDNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTKSILKLQKSQKLSNLIHKWWNEFNITEPCDTKEKGSIPTALDVHQVGGVFLLLGVGFIFASMVSVIELYVTYCEGTCKWNVPFHIYFQKELQFAVRFMSSSKKPLNTYNVDNKSRE  L
Sbjct:    1 MPTISSFPFLLMLLGRPILSKELSKIYLTIGVIFEANDDVSRKVVSVAVQNANSQLMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLLNQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHI---------------KQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKSPVTETNEVIKPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGLFSFLSPLSPLVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCDDNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTKSILKLQKSQKLSNLIHKWWNEFNITEPCDTKEKGSIPTALDVHQVGGVFLLLGVGFIFASMVSVIELYVTYCEGTCKWNVPFHIYFQKELQFAVRFMSSSKKPLNTYNVDNKSRERLL 886          

HSP 2 Score: 153.68 bits (387), Expect = 1.115e-37
Identity = 72/73 (98.63%), Postives = 72/73 (98.63%), Query Frame = 2
Query: 2789 RLLILDYKQENYNAPSNRTSLHLHNPSKTSRNYPTPTNTPRIFTELDESCNDDKNCLNISHDSLESISNMCGV 3007
            RLLILDYKQENYNAPSNRTSLHLHNPSKTSRNYPT TNTPRIFTELDESCNDDKNCLNISHDSLESISNMCGV
Sbjct:  884 RLLILDYKQENYNAPSNRTSLHLHNPSKTSRNYPTTTNTPRIFTELDESCNDDKNCLNISHDSLESISNMCGV 956          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Planmine SMEST
Match: SMESG000005199.1 (SMESG000005199.1)

HSP 1 Score: 1231.08 bits (3184), Expect = 0.000e+0
Identity = 599/893 (67.08%), Postives = 745/893 (83.43%), Query Frame = 3
Query:  114 FPFLLMLLG-RPILSKELSKIYLTIGVIFEANDDVSRKVVSVAVQNANSQLMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLLNQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNEEAQRKQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKSPVTETNEVIKPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCDDNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKGSIPTALDVHQXXXXXXXXXXXXXXASMVSVIELYVTYCEGTCKWNVPFHIYFQKELQFAVRFMSSSKKPLNTYNVDNKSRE 2789
            F F++  L   PI +KELSK  L IGVI +A+DD+SRKV+S+AVQNAN +L R+NY+F++ TET+DDN SF  IRK CNL+++GLVA+I+P++E+PSRH+SS  ++FHIPHLVT C+FPES   YPM+I+L PNCD YA +I+QYITQ+E W +MI+IH SDNCI+K+E+LLNQFE  FKMRQW+H DLKKNK+ LR+L KS+K+++FLVD+PYW+I DFLIM S HN+T P  SFIFTDWDA ++D++ FKINNKVNIT FS+ + S++  +   ++N+  L+E+I E  K SKK  I    ++ PAI+ D++N L +G+IRL+K +P+  +PMKC +N TW  G SL NA+T+ +++YG+TG+I+FNE AQRK YNLS+MELTENGF K G+WN + FV+ P + +  V E   +++PL+VTTI+S PFVFYK+  PD + +DT+++AWNGFCIDLL EIG DL +NF+IHLVKDNKYG  V+N+TNPDGSEKWNGMIGELI+K+A+L +APMTISYEREKVVDFTTPFMSLGLSILFL P+KEAPGLFSFLSP+S  VWVY+ISAYIGVS II+FISHVTPYEWLQIHPCDDN    NQFN+LNSLWFTV ALMRQGLEFCPQASSTRMVS AWWFFTLIIISTYTANLAAFLTVEQ++LPIKSVEDL  Q  IKYGTLKGG S  FFE+ALI TY+KM K+M+ N +V V STE+GV+KV  SNGKYAFLLESAMND+Y +R+C+L+R+GD+LDSKGYGIGFP+GSPLRD MTKSILKLQKSQK++NLIHKWWNE NITEPCD+KE GS+PT L+V+Q+GG+F+LL  GFIFA++VS+IELYV YC    +W +PF  Y +KELQFA+RFMSSSKKPL+    ++KSRE
Sbjct:    4 FGFVIFFLSICPISTKELSKKLLNIGVILDASDDISRKVISLAVQNANKELARFNYAFQVKTETLDDNNSFYAIRKGCNLIRHGLVAMISPIAEVPSRHISSLCSKFHIPHLVTSCRFPESLDRYPMDIQLTPNCDQYAKMIYQYITQVEIWRDMILIHSSDNCILKFEHLLNQFESRFKMRQWVHHDLKKNKKLLRELGKSKKYRYFLVDIPYWQITDFLIMASVHNMTDPQFSFIFTDWDASLVDIAAFKINNKVNITTFSITDHSIMERMTKTYENVEKLLESIVEMEKTSKKCDIEKAFMSKPAILFDTVNFLTKGIIRLLKSRPLIVRPMKCKSNDTWRLGSSLINAMTAAENLYGITGKILFNENAQRKNYNLSIMELTENGFQKGGFWNDDRFVVLPKRIEPSVVEIGNIVRPLKVTTIISQPFVFYKEGEPDRQNYDTNMEAWNGFCIDLLREIGNDLGMNFTIHLVKDNKYGEAVENQTNPDGSEKWNGMIGELITKQAELAMAPMTISYEREKVVDFTTPFMSLGLSILFLKPKKEAPGLFSFLSPISFPVWVYIISAYIGVSFIIFFISHVTPYEWLQIHPCDDNSELDNQFNLLNSLWFTVGALMRQGLEFCPQASSTRMVSGAWWFFTLIIISTYTANLAAFLTVEQLILPIKSVEDLAQQTNIKYGTLKGGTSFTFFEKALIPTYQKMFKFMKKNREVFVDSTEKGVNKVRNSNGKYAFLLESAMNDFYSQRDCSLMRIGDLLDSKGYGIGFPSGSPLRDHMTKSILKLQKSQKIANLIHKWWNEMNITEPCDSKESGSVPTELNVYQIGGIFILLVGGFIFAAIVSIIELYVDYCNKKSQWKIPFGKYLKKELQFAMRFMSSSKKPLHPDLTNSKSRE 896          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Planmine SMEST
Match: SMESG000005201.1 (SMESG000005201.1)

HSP 1 Score: 1175.23 bits (3039), Expect = 0.000e+0
Identity = 586/890 (65.84%), Postives = 728/890 (81.80%), Query Frame = 3
Query:  120 FLLMLLGRPILSKELSKIYLTIGVIFEANDDVSRKVVSVAVQNANSQLMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLLNQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNEEAQRKQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKSPVTETNEVIKPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCDDNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLIIISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERALIQTYKKMHKYMENNPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYKERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTXXXXXXXXXXXXXXXXHKWWNEFNITEPCDTKEKGSIPTALDVHQXXXXXXXXXXXXXXASMVSVIELYVTYCEGTCKWNVPFHIYFQKELQFAVRFMSSSKKPLNTYNVDNKSRE 2789
            FLL+L      S+E  K  LTIGVI   NDD+SRKV+ +A+Q AN +L + NY+ ++ TET+++N SF VIRK CNL+++GLVA+I+P++E+PSRH+SS  ++FHIPHLVT C+FPES   YPM+I++ P+CD YA II+QYITQ+E W +MI+IH SDNCI+K+E+LLNQFE  FKMRQW+H DLKKNK+   +L+KS+K+++FLVD+PYW+I DFLIM S HN+T P  SFIF+DWDA ++D++ FKINNKVNIT FS+++  L+   +    +L SL+++I +  K SK + I T  ++ PAI+ D+I+ L++G+I ++K +P   +P+KC++NT WN G SL NAITS + + G TG+I+FNE++QR+ YNLSVM LTENGF + G W  +  +    K ++  TE ++V +PL+VTTI++LPFVFYK+  P+  ++DT+IDAWNGFCIDLL EIG+DL LNFSIHLVKD  +GTV+ NET PDGSEKW+GMIGELISKE DLVVAPMTISYEREKVVDFTTPFMSLGLSI+FL PQKEAPGLFSFLSP+SP VWVYVIS YI  SLII+FISH+TPYEW+  HPCDD  S+ NQFN+LNSLWFTV AL+RQGLEFCPQASSTRMVS AWWFFTLIIISTYTANLAAFLTVEQ++LPIKSVEDLVNQ  IKYGTL+GGAS+AFFE ALI TYKKM  +M+ NPD MV +T++GV KV  S GKYAFLLESAMNDYY +R+C LIRVGD+LDSKGYGIGFPTGSPLRDKMT+SILKLQKSQK++NLIHKWWNE N+TEPCDTK+KGSIP +L+V+QVGGVF LLG GFIFA  VS+IELYV + E   +W +PF  + +KELQFA+RFMSSSKKP    N + KSRE
Sbjct:    7 FLLLLFICSTESQESPKENLTIGVILNYNDDISRKVIGMAIQKANIELAKLNYALQVKTETLEENSSFFVIRKGCNLIRHGLVAMISPIAEVPSRHISSLCSKFHIPHLVTSCRFPESLDKYPMDIQITPDCDQYAKIIYQYITQVEIWRDMILIHSSDNCILKFEHLLNQFESRFKMRQWVHHDLKKNKQLFWELSKSQKYRYFLVDIPYWQITDFLIMASVHNMTDPQFSFIFSDWDANLVDIAAFKINNKVNITTFSIVDHKLIAKTKDVQSDLKSLIDSIIKMEKSSKNADIETKFMSTPAILFDAISTLLKGIIHMLKTRPFSVKPLKCSSNTIWNLGPSLVNAITSAEAIQGFTGKIIFNEKSQRENYNLSVMGLTENGFEESGRWVEDQLITSIKKQEAVSTEVDKVKQPLKVTTIINLPFVFYKEGIPNRNDYDTNIDAWNGFCIDLLKEIGSDLGLNFSIHLVKDGLFGTVIPNETYPDGSEKWSGMIGELISKEVDLVVAPMTISYEREKVVDFTTPFMSLGLSIMFLAPQKEAPGLFSFLSPISPPVWVYVISVYILTSLIIFFISHITPYEWMISHPCDDESSKHNQFNLLNSLWFTVGALVRQGLEFCPQASSTRMVSGAWWFFTLIIISTYTANLAAFLTVEQLILPIKSVEDLVNQTKIKYGTLRGGASQAFFENALIYTYKKMDAFMKKNPDSMVATTDDGVAKVRNSKGKYAFLLESAMNDYYAQRDCKLIRVGDLLDSKGYGIGFPTGSPLRDKMTESILKLQKSQKIANLIHKWWNEINVTEPCDTKDKGSIPQSLNVNQVGGVFFLLGAGFIFAGFVSIIELYVDFREKKSQWKMPFCKFLKKELQFAMRFMSSSKKPTRPNNNNGKSRE 896          
BLAST of Glutamate receptor ionotropic kainate 3 vs. Planmine SMEST
Match: SMESG000005199.1 (SMESG000005199.1)

HSP 1 Score: 847.425 bits (2188), Expect = 0.000e+0
Identity = 392/615 (63.74%), Postives = 502/615 (81.63%), Query Frame = 3
Query:  114 FPFLLMLLG-RPILSKELSKIYLTIGVIFEANDDVSRKVVSVAVQNANSQLMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSEIPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQYITQIEAWGEMIIIHKSDNCIMKYEYLLNQFEYHFKMRQWIHGDLKKNKEFLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDARILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLSKKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWNQGISLFNAITSVDHMYGLTGRIVFNEEAQRKQYNLSVMELTENGFMKKGYWNGNNFVIFPPKSKSPVTETNEVIKPLRVTTIVSLPFVFYKDNSPDIKEHDTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSEKWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQKEAPGXXXXXXXXXXXVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCDDNGSRQNQFNILNSLWFTVAA 1955
            F F++  L   PI +KELSK  L IGVI +A+DD+SRKV+S+AVQNAN +L R+NY+F++ TET+DDN SF  IRK CNL+++GLVA+I+P++E+PSRH+SS  ++FHIPHLVT C+FPES   YPM+I+L PNCD YA +I+QYITQ+E W +MI+IH SDNCI+K+E+LLNQFE  FKMRQW+H DLKKNK+ LR+L KS+K+++FLVD+PYW+I DFLIM S HN+T P  SFIFTDWDA ++D++ FKINNKVNIT FS+ + S++  +   ++N+  L+E+I E  K SKK  I    ++ PAI+ D++N L +G+IRL+K +P+  +PMKC +N TW  G SL NA+T+ +++YG+TG+I+FNE AQRK YNLS+MELTENGF K G+WN + FV+ P + +  V E   +++PL+VTTI+S PFVFYK+  PD + +DT+++AWNGFCIDLL EIG DL +NF+IHLVKDNKYG  V+N+TNPDGSEKWNGMIGELI+K+A+L +APMTISYEREKVVDFTTPFMSLGLSILFL P+KEAPGLFSFLSP+S  VWVY+ISAYIGVS II+FISHVTPYEWLQIHPCDDN    NQFN+LNSLWFTV  
Sbjct:    4 FGFVIFFLSICPISTKELSKKLLNIGVILDASDDISRKVISLAVQNANKELARFNYAFQVKTETLDDNNSFYAIRKGCNLIRHGLVAMISPIAEVPSRHISSLCSKFHIPHLVTSCRFPESLDRYPMDIQLTPNCDQYAKMIYQYITQVEIWRDMILIHSSDNCILKFEHLLNQFESRFKMRQWVHHDLKKNKKLLRELGKSKKYRYFLVDIPYWQITDFLIMASVHNMTDPQFSFIFTDWDASLVDIAAFKINNKVNITTFSITDHSIMERMTKTYENVEKLLESIVEMEKTSKKCDIEKAFMSKPAILFDTVNFLTKGIIRLLKSRPLIVRPMKCKSNDTWRLGSSLINAMTAAENLYGITGKILFNENAQRKNYNLSIMELTENGFQKGGFWNDDRFVVLPKRIEPSVVEIGNIVRPLKVTTIISQPFVFYKEGEPDRQNYDTNMEAWNGFCIDLLREIGNDLGMNFTIHLVKDNKYGEAVENQTNPDGSEKWNGMIGELITKQAELAMAPMTISYEREKVVDFTTPFMSLGLSILFLKPKKEAPGLFSFLSPISFPVWVYIISAYIGVSFIIFFISHVTPYEWLQIHPCDDNSELDNQFNLLNSLWFTVKC 618          
The following BLAST results are available for this feature:
BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
GRIK21.773e-13434.94glutamate ionotropic receptor kainate type subunit... [more]
GRIK22.593e-13434.56glutamate ionotropic receptor kainate type subunit... [more]
GRIK22.632e-13434.68glutamate ionotropic receptor kainate type subunit... [more]
GRIK22.679e-13434.68glutamate ionotropic receptor kainate type subunit... [more]
GRIK25.290e-13434.31glutamate ionotropic receptor kainate type subunit... [more]
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BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
glr-31.011e-10531.44GLutamate Receptor family (AMPA) [Source:UniProtK... [more]
glr-56.986e-9830.02GLutamate Receptor family (AMPA) [Source:UniProtK... [more]
glr-41.055e-9431.14GLutamate Receptor family (AMPA) [Source:UniProtK... [more]
glr-43.892e-9431.14GLutamate Receptor family (AMPA) [Source:UniProtK... [more]
glr-24.886e-8931.48Glutamate receptor 2 [Source:UniProtKB/Swiss-Prot... [more]
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BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
KaiR1D4.408e-14036.37gene:FBgn0038837 transcript:FBtr0083987[more]
CG111558.629e-13035.22gene:FBgn0039927 transcript:FBtr0333701[more]
CG111558.629e-13035.22gene:FBgn0039927 transcript:FBtr0089195[more]
Grik9.544e-12532.04gene:FBgn0038840 transcript:FBtr0335015[more]
Ekar3.563e-12434.97gene:FBgn0039916 transcript:FBtr0110906[more]
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BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
grik1a4.127e-13135.10glutamate receptor, ionotropic, kainate 1a [Source... [more]
grik1a8.465e-13034.68glutamate receptor, ionotropic, kainate 1a [Source... [more]
GRIK21.768e-12833.71glutamate receptor, ionotropic, kainate 2 [Source:... [more]
GRIK21.768e-12833.71glutamate receptor, ionotropic, kainate 2 [Source:... [more]
grik1b2.855e-12833.93glutamate receptor, ionotropic, kainate 1b [Source... [more]
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BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
GRIK41.629e-13343.92glutamate receptor, ionotropic, kainate 4 [Source:... [more]
GRIK15.043e-13333.33glutamate receptor, ionotropic, kainate 1 [Source:... [more]
GRIK41.090e-13241.75glutamate receptor, ionotropic, kainate 4 [Source:... [more]
GRIK41.133e-13242.45glutamate receptor, ionotropic, kainate 4 [Source:... [more]
GRIK41.288e-13242.45glutamate receptor, ionotropic, kainate 4 [Source:... [more]
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BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Grik25.358e-13434.69glutamate receptor, ionotropic, kainate 2 (beta 2)... [more]
Grik26.068e-13434.69glutamate receptor, ionotropic, kainate 2 (beta 2)... [more]
Grik26.068e-13434.69glutamate receptor, ionotropic, kainate 2 (beta 2)... [more]
Grik29.412e-13434.69glutamate receptor, ionotropic, kainate 2 (beta 2)... [more]
Grik29.412e-13434.69glutamate receptor, ionotropic, kainate 2 (beta 2)... [more]
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BLAST of Glutamate receptor ionotropic kainate 3 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q13002|GRIK2_HUMAN2.541e-13334.31Glutamate receptor ionotropic, kainate 2 OS=Homo s... [more]
sp|P39087|GRIK2_MOUSE6.583e-13334.69Glutamate receptor ionotropic, kainate 2 OS=Mus mu... [more]
sp|Q38PU3|GRIK2_MACFA7.010e-13334.43Glutamate receptor ionotropic, kainate 2 OS=Macaca... [more]
sp|P42260|GRIK2_RAT8.116e-13334.56Glutamate receptor ionotropic, kainate 2 OS=Rattus... [more]
sp|Q01812|GRIK4_RAT1.765e-12936.87Glutamate receptor ionotropic, kainate 4 OS=Rattus... [more]
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BLAST of Glutamate receptor ionotropic kainate 3 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4E0RD830.000e+039.02Glutamate receptor ionotropic kainate 3 OS=Fasciol... [more]
A0A095BTF90.000e+041.13Glutamate receptor ionotropic, kainate 3 OS=Schist... [more]
A0A3Q0KQ550.000e+040.74Putative glutamate receptor, kainate OS=Schistosom... [more]
A0A4Z2CN370.000e+040.14Glutamate receptor ionotropic, kainate 3 isoform 5... [more]
A0A4S2LMY30.000e+039.66Uncharacterized protein OS=Opisthorchis felineus O... [more]
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BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
si:ch211-264f5.83.649e-13234.90si:ch211-264f5.8 [Source:ZFIN;Acc:ZDB-GENE-081104-... [more]
ENSAMXT00000004586.22.106e-13135.04glutamate receptor ionotropic, kainate 2-like [Sou... [more]
grik1a5.137e-13134.27glutamate receptor ionotropic, kainate 1 [Source:N... [more]
grik1b1.364e-12933.79glutamate receptor ionotropic, kainate 1 [Source:N... [more]
grik1b5.171e-12934.26glutamate receptor ionotropic, kainate 1 [Source:N... [more]
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BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
gria1b4.163e-9842.73glutamate receptor, ionotropic, AMPA 1b [Source:ZF... [more]
ENSPMAT00000005084.13.478e-8950.68pep scaffold:Pmarinus_7.0:GL476900:54926:87395:-1 ... [more]
ENSPMAT00000002503.12.336e-5647.62pep scaffold:Pmarinus_7.0:GL492163:1:1446:1 gene:E... [more]
ENSPMAT00000010716.11.213e-2928.92pep scaffold:Pmarinus_7.0:GL476465:413535:454465:1... [more]
ENSPMAT00000007790.11.619e-2729.96pep scaffold:Pmarinus_7.0:GL476616:796957:798868:-... [more]
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BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO412919.926e-5832.66Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO302032.243e-5631.13Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO355451.429e-5429.98Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO466331.245e-4629.15Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO412937.615e-3931.32Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Glutamate receptor ionotropic kainate 3 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
grik1a4.819e-13233.91glutamate receptor ionotropic, kainate 1 [Source:N... [more]
grik1b8.103e-13134.24glutamate ionotropic receptor kainate type subunit... [more]
grik1a8.119e-13134.87glutamate receptor ionotropic, kainate 1 [Source:N... [more]
grik1a1.353e-13034.87glutamate receptor ionotropic, kainate 1 [Source:N... [more]
grik52.978e-13035.07glutamate ionotropic receptor kainate type subunit... [more]
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BLAST of Glutamate receptor ionotropic kainate 3 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000005192.11.034e-3798.00SMESG000005192.1[more]
SMESG000005192.11.115e-3798.00SMESG000005192.1[more]
SMESG000005199.10.000e+067.08SMESG000005199.1[more]
SMESG000005201.10.000e+065.84SMESG000005201.1[more]
SMESG000005199.10.000e+063.74SMESG000005199.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30020437 ID=SMED30020437|Name=Glutamate receptor ionotropic kainate 3|organism=Schmidtea mediterranea sexual|type=transcript|length=3085bp
TTCTGATTGGCTGAAAAATCGTTAAATAGTGCGTAACTGTGCTTTGAATA
TAATCTCAATTCTGTCGATTGGAACATGCATAAATCAATAGAATGATGCC
AACAATTTCCTCCTTTCCTTTCCTCCTGATGCTGCTCGGTCGTCCAATCT
TGTCGAAGGAATTATCCAAAATTTACTTGACTATCGGAGTTATTTTTGAA
GCCAATGATGATGTCTCAAGAAAGGTTGTTAGTGTCGCCGTTCAGAATGC
TAATTCACAACTAATGAGATACAATTATTCATTCCGGATAGTAACTGAGA
CTGTAGATGACAATGGTAGCTTCAGTGTAATTAGGAAAGCCTGTAATTTG
TTGCAAAACGGACTGGTTGCACTAATTGCTCCTCTCTCAGAAATTCCATC
AAGGCATTTGTCCTCATTCTCCAATAGGTTCCATATTCCACATTTAGTAA
CTAAGTGTCAGTTCCCAGAATCATCCGCCTCATATCCAATGAATATAAAG
TTGTATCCGAATTGCGATGCGTATGCCAACATCATCTTTCAATACATTAC
TCAAATTGAGGCCTGGGGTGAAATGATAATTATCCATAAGTCCGATAATT
GCATAATGAAATATGAATATCTTCTCAACCAATTTGAATATCATTTCAAA
ATGAGGCAATGGATCCACGGGGATCTTAAAAAAAATAAGGAATTCTTGAG
GAAATTGGCCAAAAGCAGGAAACATAAACACTTTTTAGTTGACCTTCCTT
ACTGGGAAATCAGGGATTTTCTAATTATGGTGTCTACTCACAATCTGACA
GGACCTGCACACTCATTCATTTTCACAGATTGGGATGCCAGAATCCTTGA
TCTATCAGTATTTAAGATTAATAACAAAGTAAACATCACTGCATTTTCAC
TGATTAACGACTCGCTTGTGACGAGTCTCAGAACGAGACATAAGAACCTC
AACAGTCTAATGGAAAATATTTTTGAATCTAGAAAATTATCGAAAAAAAG
TTTTATAAATACGAATTTGTTGGCAGCCCCAGCAATAATCATTGACTCAA
TAAACGTGTTGATGGAGGGCCTGATACGACTGATCAAACTGCAGCCCGTT
TTCACGCAGCCAATGAAGTGCACAACAAATACGACTTGGAATCAAGGAAT
AAGTCTTTTCAACGCAATAACTTCGGTTGACCACATGTACGGATTAACGG
GGAGAATAGTATTCAATGAAGAAGCCCAAAGAAAGCAATATAATTTATCA
GTAATGGAATTAACAGAAAACGGATTTATGAAAAAAGGCTATTGGAATGG
GAACAACTTTGTGATATTCCCACCGAAGTCTAAATCTCCGGTGACTGAAA
CGAATGAAGTAATAAAACCTTTGAGAGTTACGACTATTGTGAGTCTCCCG
TTCGTGTTTTACAAGGACAATTCTCCAGACATCAAAGAACACGACACAAG
CATCGACGCTTGGAATGGGTTCTGCATTGATCTACTGAATGAGATCGGAG
CTGACCTAAGATTAAATTTTTCGATCCACCTCGTGAAGGATAACAAGTAT
GGGACAGTCGTTGACAACGAAACGAACCCAGACGGATCTGAGAAGTGGAA
TGGAATGATTGGTGAACTCATTTCAAAAGAAGCTGATCTCGTTGTCGCTC
CAATGACAATTTCATATGAGAGAGAGAAAGTTGTTGATTTCACGACTCCC
TTCATGAGCCTAGGTCTCAGCATTTTGTTTCTGACTCCACAAAAAGAAGC
TCCCGGGCTGTTTTCCTTTTTATCGCCCCTTTCACCACTGGTTTGGGTCT
ATGTTATCAGTGCGTACATCGGTGTCAGTTTGATTATTTACTTTATTTCT
CACGTCACTCCATACGAATGGCTTCAGATTCACCCTTGTGACGACAACGG
TTCTCGTCAAAATCAGTTCAATATTTTGAATAGTCTTTGGTTTACTGTTG
CAGCATTAATGCGACAAGGATTAGAGTTTTGTCCACAAGCTTCCTCGACT
CGAATGGTTTCAAGTGCTTGGTGGTTTTTTACATTAATCATTATTTCAAC
TTACACTGCCAACCTTGCGGCCTTTCTAACAGTTGAACAAATTGTGCTTC
CAATAAAGAGTGTTGAGGACTTAGTCAATCAAAAGACTATTAAGTATGGA
ACATTAAAAGGAGGAGCTTCCGAAGCATTTTTTGAGAGAGCACTCATTCA
AACCTATAAGAAAATGCACAAATACATGGAAAATAATCCAGATGTTATGG
TACGGAGTACTGAAGAAGGAGTGGATAAAGTATTGAAATCTAATGGTAAA
TATGCATTCCTATTGGAGTCTGCTATGAACGATTACTACAAAGAAAGGGA
GTGCACCCTCATACGAGTTGGTGATATGCTTGATTCAAAAGGGTATGGGA
TAGGATTTCCAACTGGCTCCCCTTTGCGTGACAAAATGACTAAATCAATC
CTAAAGCTTCAGAAGTCTCAAAAACTGTCTAATTTGATTCATAAGTGGTG
GAATGAATTCAATATCACTGAACCTTGCGATACAAAGGAAAAAGGTTCAA
TACCAACTGCTTTAGATGTCCATCAAGTTGGAGGAGTGTTTTTGTTATTA
GGAGTTGGCTTTATATTTGCCAGTATGGTATCGGTCATTGAATTATATGT
AACTTACTGTGAGGGAACTTGTAAATGGAACGTACCTTTCCATATATATT
TCCAGAAGGAATTGCAGTTTGCTGTTAGATTTATGAGTTCCTCAAAAAAA
CCCTTGAACACTTATAATGTGGACAACAAAAGTAGAGAAGATTGCTTATA
TTGGATTATAAGCAGGAAAATTACAACGCACCTTCAAATAGGACGTCACT
TCATCTTCATAATCCCAGCAAAACATCTCGTAATTATCCCACTCCAACGA
ACACTCCACGGATATTTACTGAACTGGATGAATCTTGTAATGATGATAAA
AACTGCCTCAATATTTCTCATGACTCCCTTGAAAGTATCTCCAACATGTG
CGGAGTCTAAATGAAAATTGAGTATTTTTGATTTATTTTATATTTTTTCG
TGTAACCGATTTTTGGAAAATACCTCTCTTACGCG
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protein sequence of SMED30020437-orf-1

>SMED30020437-orf-1 ID=SMED30020437-orf-1|Name=SMED30020437-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=974bp
MMPTISSFPFLLMLLGRPILSKELSKIYLTIGVIFEANDDVSRKVVSVAV
QNANSQLMRYNYSFRIVTETVDDNGSFSVIRKACNLLQNGLVALIAPLSE
IPSRHLSSFSNRFHIPHLVTKCQFPESSASYPMNIKLYPNCDAYANIIFQ
YITQIEAWGEMIIIHKSDNCIMKYEYLLNQFEYHFKMRQWIHGDLKKNKE
FLRKLAKSRKHKHFLVDLPYWEIRDFLIMVSTHNLTGPAHSFIFTDWDAR
ILDLSVFKINNKVNITAFSLINDSLVTSLRTRHKNLNSLMENIFESRKLS
KKSFINTNLLAAPAIIIDSINVLMEGLIRLIKLQPVFTQPMKCTTNTTWN
QGISLFNAITSVDHMYGLTGRIVFNEEAQRKQYNLSVMELTENGFMKKGY
WNGNNFVIFPPKSKSPVTETNEVIKPLRVTTIVSLPFVFYKDNSPDIKEH
DTSIDAWNGFCIDLLNEIGADLRLNFSIHLVKDNKYGTVVDNETNPDGSE
KWNGMIGELISKEADLVVAPMTISYEREKVVDFTTPFMSLGLSILFLTPQ
KEAPGLFSFLSPLSPLVWVYVISAYIGVSLIIYFISHVTPYEWLQIHPCD
DNGSRQNQFNILNSLWFTVAALMRQGLEFCPQASSTRMVSSAWWFFTLII
ISTYTANLAAFLTVEQIVLPIKSVEDLVNQKTIKYGTLKGGASEAFFERA
LIQTYKKMHKYMENNPDVMVRSTEEGVDKVLKSNGKYAFLLESAMNDYYK
ERECTLIRVGDMLDSKGYGIGFPTGSPLRDKMTKSILKLQKSQKLSNLIH
KWWNEFNITEPCDTKEKGSIPTALDVHQVGGVFLLLGVGFIFASMVSVIE
LYVTYCEGTCKWNVPFHIYFQKELQFAVRFMSSSKKPLNTYNVDNKSRED
CLYWIISRKITTHLQIGRHFIFIIPAKHLVIIPLQRTLHGYLLNWMNLVM
MIKTASIFLMTPLKVSPTCAESK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0015276ligand-gated ion channel activity
GO:0038023signaling receptor activity
GO:0004872receptor activity
GO:0005216ion channel activity
GO:0004970ionotropic glutamate receptor activity
GO:0005234extracellular-glutamate-gated ion channel activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000101muscle cell
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR001508Iono_rcpt_met
IPR001320Iontro_rcpt
IPR019594Glu/Gly-bd
IPR001828ANF_lig-bd_rcpt
IPR028082Peripla_BP_I
Vocabulary: biological process
TermDefinition
GO:0006811ion transport
GO:0006810transport
GO:0034220ion transmembrane transport
GO:0035235ionotropic glutamate receptor signaling pathway
GO:0060079excitatory postsynaptic potential
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0005886plasma membrane
GO:0016021integral component of membrane
GO:0030054cell junction
GO:0045202synapse
GO:0045211postsynaptic membrane