mitfl-1 protein

Overview


Name	mitfl-1 protein (AGZ94932.1)
Smed ID	SMED30020410
Length (bp)	1818

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of mitfl-1 protein (SMED30020410) t-SNE clustered cells

Violin plots show distribution of expression levels for mitfl-1 protein (SMED30020410) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of mitfl-1 protein (SMED30020410) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for mitfl-1 protein (SMED30020410) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30020410

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
gut	SMED30020410	h1SMcG0009686	dd_Smed_v4_7938_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30020410	h1SMcG0009686	dd_Smed_v4_7938_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30020410	h1SMcG0009686	dd_Smed_v4_7938_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30020410	h1SMcG0009686	dd_Smed_v4_7938_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of mitfl-1 protein vs. Ensembl Human
Match: MITF (melanocyte inducing transcription factor [Source:HGNC Symbol;Acc:HGNC:7105])

HSP 1 Score: 69.3218 bits (168), Expect = 1.094e-11
Identity = 68/219 (31.05%), Postives = 106/219 (48.40%), Query Frame = 1

Query:  370 VDDFIALESNYHRRNDSPYIVSPACQYDKYNILQYSSDYV-IDSKQDLPMQYRDNTSKSLLQPYEVLNNKNDISLSCPVTGERSEVSMNHAMSSCNFPPTPSSSVQGQYQNDNLKNQKDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNE---FNNISNYVKETEMA--FMLLETYRKRNQELENQIKTY 1008
            +DD I+LES+Y+       ++ PA Q    N L  S + + +   Q LP             P   ++N      SCP     +  ++   +++C FP           +++     K+R KK++HN IER+RR  IN +I ELG LIP   ++D + + NKG ILK SV+Y+ +L+ E      + N  K+ E A   +LL     R QELE Q + +
Sbjct:  227 IDDIISLESSYNEEILG--LMDPALQM--ANTLPVSGNLIDLYGNQGLP------------PPGLTISN------SCPA----NLPNIKRELTACIFP----------TESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPK--SNDPDMRWNKGTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLL-----RIQELEMQARAH 402

[Close]

BLAST of mitfl-1 protein vs. Ensembl Human
Match: MITF (melanocyte inducing transcription factor [Source:HGNC Symbol;Acc:HGNC:7105])

HSP 1 Score: 68.5514 bits (166), Expect = 1.411e-11
Identity = 68/219 (31.05%), Postives = 107/219 (48.86%), Query Frame = 1

Query:  370 VDDFIALESNYHRRNDSPYIVSPACQYDKYNILQYSSDYV-IDSKQDLPMQYRDNTSKSLLQPYEVLNNKNDISLSCPVTGERSEVSMNHAMSSCNFPPTPSSSVQGQYQNDNLKNQKDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNE---FNNISNYVKETEMA--FMLLETYRKRNQELENQIKTY 1008
            +DD I+LES+Y+   +   ++ PA Q    N L  S + + +   Q LP             P   ++N      SCP     +  ++   +++C FP           +++     K+R KK++HN IER+RR  IN +I ELG LIP   ++D + + NKG ILK SV+Y+ +L+ E      + N  K+ E A   +LL     R QELE Q + +
Sbjct:  120 IDDIISLESSYNE--EILGLMDPALQM--ANTLPVSGNLIDLYGNQGLP------------PPGLTISN------SCPA----NLPNIKRELTACIFP----------TESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPK--SNDPDMRWNKGTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLL-----RIQELEMQARAH 295

[Close]

BLAST of mitfl-1 protein vs. Ensembl Human
Match: TFEB (transcription factor EB [Source:HGNC Symbol;Acc:HGNC:11753])

HSP 1 Score: 67.781 bits (164), Expect = 2.102e-11
Identity = 46/114 (40.35%), Postives = 65/114 (57.02%), Query Frame = 1

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNN---ISNYVKETEMAFMLLETYRKRNQELENQIKTYYSNTTNSIDSQNLA 1050
            K+R KK++HN IER+RR  IN +I ELG LIP    +D + + NKG ILK SV+Y+ R++ +      + N+ +  EM    L     R QELE Q + +   TT S    N+A
Sbjct:  147 KERQKKDNHNLIERRRRFNINDRIKELGMLIPKA--NDLDVRWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWL---RIQELEMQARVHGLPTT-SPSGMNMA 254

[Close]

BLAST of mitfl-1 protein vs. Ensembl Human
Match: TFEB (transcription factor EB [Source:HGNC Symbol;Acc:HGNC:11753])

HSP 1 Score: 67.0106 bits (162), Expect = 2.194e-11
Identity = 46/114 (40.35%), Postives = 65/114 (57.02%), Query Frame = 1

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNN---ISNYVKETEMAFMLLETYRKRNQELENQIKTYYSNTTNSIDSQNLA 1050
            K+R KK++HN IER+RR  IN +I ELG LIP    +D + + NKG ILK SV+Y+ R++ +      + N+ +  EM    L     R QELE Q + +   TT S    N+A
Sbjct:   90 KERQKKDNHNLIERRRRFNINDRIKELGMLIPKA--NDLDVRWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWL---RIQELEMQARVHGLPTT-SPSGMNMA 197

[Close]

BLAST of mitfl-1 protein vs. Ensembl Human
Match: TFEB (transcription factor EB [Source:HGNC Symbol;Acc:HGNC:11753])

HSP 1 Score: 67.781 bits (164), Expect = 2.787e-11
Identity = 46/114 (40.35%), Postives = 65/114 (57.02%), Query Frame = 1

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNN---ISNYVKETEMAFMLLETYRKRNQELENQIKTYYSNTTNSIDSQNLA 1050
            K+R KK++HN IER+RR  IN +I ELG LIP    +D + + NKG ILK SV+Y+ R++ +      + N+ +  EM    L     R QELE Q + +   TT S    N+A
Sbjct:  246 KERQKKDNHNLIERRRRFNINDRIKELGMLIPKA--NDLDVRWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWL---RIQELEMQARVHGLPTT-SPSGMNMA 353

[Close]

BLAST of mitfl-1 protein vs. Ensembl Celegans
Match: hlh-30 (Helix Loop Helix [Source:UniProtKB/TrEMBL;Acc:Q86MJ3])

HSP 1 Score: 58.151 bits (139), Expect = 8.812e-9
Identity = 34/94 (36.17%), Postives = 52/94 (55.32%), Query Frame = 1

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRKRNQELENQI 999
            +DR KK+ HN IER+RR  IN +I ELG+++P   N+  + K NKG ILK S +Y+  L+ +        ++ +        Y  R +ELE  +
Sbjct:   97 RDRRKKDIHNMIERRRRYNINDRIKELGQMLPK--NTSEDMKLNKGTILKASCDYIRVLQKDREQAMKTQQQQKSLESTAHKYADRVKELEEML 188

[Close]

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRKRNQELENQI 999
            +DR KK+ HN IER+RR  IN +I ELG+++P   N+  + K NKG ILK S +Y+  L+ +        ++ +        Y  R +ELE  +
Sbjct:   97 RDRRKKDIHNMIERRRRYNINDRIKELGQMLPK--NTSEDMKLNKGTILKASCDYIRVLQKDREQAMKTQQQQKSLESTAHKYADRVKELEEML 188

[Close]

BLAST of mitfl-1 protein vs. Ensembl Celegans
Match: hlh-30 (Helix Loop Helix [Source:UniProtKB/TrEMBL;Acc:Q86MJ3])

HSP 1 Score: 58.151 bits (139), Expect = 1.037e-8
Identity = 34/94 (36.17%), Postives = 52/94 (55.32%), Query Frame = 1

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRKRNQELENQI 999
            +DR KK+ HN IER+RR  IN +I ELG+++P   N+  + K NKG ILK S +Y+  L+ +        ++ +        Y  R +ELE  +
Sbjct:  209 RDRRKKDIHNMIERRRRYNINDRIKELGQMLPK--NTSEDMKLNKGTILKASCDYIRVLQKDREQAMKTQQQQKSLESTAHKYADRVKELEEML 300

[Close]

BLAST of mitfl-1 protein vs. Ensembl Celegans
Match: hlh-30 (Helix Loop Helix [Source:UniProtKB/TrEMBL;Acc:Q86MJ3])

HSP 1 Score: 58.151 bits (139), Expect = 1.065e-8
Identity = 34/94 (36.17%), Postives = 52/94 (55.32%), Query Frame = 1

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRKRNQELENQI 999
            +DR KK+ HN IER+RR  IN +I ELG+++P   N+  + K NKG ILK S +Y+  L+ +        ++ +        Y  R +ELE  +
Sbjct:  184 RDRRKKDIHNMIERRRRYNINDRIKELGQMLPK--NTSEDMKLNKGTILKASCDYIRVLQKDREQAMKTQQQQKSLESTAHKYADRVKELEEML 275

[Close]

BLAST of mitfl-1 protein vs. Ensembl Celegans
Match: hlh-30 (Helix Loop Helix [Source:UniProtKB/TrEMBL;Acc:Q86MJ3])

HSP 1 Score: 57.7658 bits (138), Expect = 1.232e-8
Identity = 34/94 (36.17%), Postives = 52/94 (55.32%), Query Frame = 1

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRKRNQELENQI 999
            +DR KK+ HN IER+RR  IN +I ELG+++P   N+  + K NKG ILK S +Y+  L+ +        ++ +        Y  R +ELE  +
Sbjct:  175 RDRRKKDIHNMIERRRRYNINDRIKELGQMLPK--NTSEDMKLNKGTILKASCDYIRVLQKDREQAMKTQQQQKSLESTAHKYADRVKELEEML 266

[Close]

BLAST of mitfl-1 protein vs. Ensembl Fly
Match: Mitf (gene:FBgn0263112 transcript:FBtr0307328)

HSP 1 Score: 62.003 bits (149), Expect = 1.273e-9
Identity = 40/102 (39.22%), Postives = 61/102 (59.80%), Query Frame = 1

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNES----KKNKGNILKNSVEYVTRLKNEFNNI-SNYVKETEMAFMLLETYRKRNQELENQIKTY 1008
            KDR KK++HN IER+RR  IN +I ELG L+P   ++  E     + NKG ILK+SV+Y+  LK+E   +  N +++ ++          R +ELE Q K++
Sbjct:  504 KDRQKKDNHNMIERRRRFNINDRIKELGTLLPKGSDAFYEVVRDIRPNKGTILKSSVDYIKCLKHEVTRLRQNELRQRQVELQ-NRKLMSRIKELEMQAKSH 604

[Close]

BLAST of mitfl-1 protein vs. Ensembl Fly
Match: Mitf (gene:FBgn0263112 transcript:FBtr0307326)

HSP 1 Score: 62.003 bits (149), Expect = 1.283e-9
Identity = 39/101 (38.61%), Postives = 56/101 (55.45%), Query Frame = 1

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNES----KKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRKRNQELENQIKTY 1008
            KDR KK++HN IER+RR  IN +I ELG L+P   ++  E     + NKG ILK+SV+Y+  LK+E   +           +       R +ELE Q K++
Sbjct:  397 KDRQKKDNHNMIERRRRFNINDRIKELGTLLPKGSDAFYEVVRDIRPNKGTILKSSVDYIKCLKHEVTRLRQNELRQRQVELQNRKLMSRIKELEMQAKSH 497

[Close]

BLAST of mitfl-1 protein vs. Ensembl Fly
Match: Mitf (gene:FBgn0263112 transcript:FBtr0307327)

HSP 1 Score: 62.003 bits (149), Expect = 1.283e-9
Identity = 39/101 (38.61%), Postives = 56/101 (55.45%), Query Frame = 1

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNES----KKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRKRNQELENQIKTY 1008
            KDR KK++HN IER+RR  IN +I ELG L+P   ++  E     + NKG ILK+SV+Y+  LK+E   +           +       R +ELE Q K++
Sbjct:  397 KDRQKKDNHNMIERRRRFNINDRIKELGTLLPKGSDAFYEVVRDIRPNKGTILKSSVDYIKCLKHEVTRLRQNELRQRQVELQNRKLMSRIKELEMQAKSH 497

[Close]

BLAST of mitfl-1 protein vs. Ensembl Fly
Match: Mitf (gene:FBgn0263112 transcript:FBtr0307329)

HSP 1 Score: 61.6178 bits (148), Expect = 1.293e-9
Identity = 39/101 (38.61%), Postives = 56/101 (55.45%), Query Frame = 1

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNES----KKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRKRNQELENQIKTY 1008
            KDR KK++HN IER+RR  IN +I ELG L+P   ++  E     + NKG ILK+SV+Y+  LK+E   +           +       R +ELE Q K++
Sbjct:  371 KDRQKKDNHNMIERRRRFNINDRIKELGTLLPKGSDAFYEVVRDIRPNKGTILKSSVDYIKCLKHEVTRLRQNELRQRQVELQNRKLMSRIKELEMQAKSH 471

[Close]

BLAST of mitfl-1 protein vs. Ensembl Zebrafish
Match: tfe3b (transcription factor binding to IGHM enhancer 3b [Source:ZFIN;Acc:ZDB-GENE-010919-3])

HSP 1 Score: 72.7886 bits (177), Expect = 3.648e-13
Identity = 52/123 (42.28%), Postives = 68/123 (55.28%), Query Frame = 1

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRK----RNQELENQIKTYYSNTTNSIDSQNLATNYHNYLL 1074
            K+R KK++HN IER+RR  IN +I ELG LIP   ++D E + NKG ILK SV+Y+ +L+ E        KE EM    LE   +    R QELE Q + +  N T S      A+   N LL
Sbjct:  223 KERQKKDNHNLIERRRRFNINDRIKELGALIPK--STDPEMRWNKGTILKASVDYIRKLQKE----QQRAKEIEMRQKKLEQSNQALILRIQELEIQARHHGLNATVSPGLNTEASFIQNQLL 339

[Close]

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRK----RNQELENQIKTYYSNTTNSIDSQNLATNYHNYLL 1074
            K+R KK++HN IER+RR  IN +I ELG LIP   ++D E + NKG ILK SV+Y+ +L+ E        KE EM    LE   +    R QELE Q + +  N T S      A+   N LL
Sbjct:  223 KERQKKDNHNLIERRRRFNINDRIKELGALIPK--STDPEMRWNKGTILKASVDYIRKLQKE----QQRAKEIEMRQKKLEQSNQALILRIQELEIQARHHGLNATVSPGLNTEASFIQNQLL 339

[Close]

BLAST of mitfl-1 protein vs. Ensembl Zebrafish
Match: tfe3b (transcription factor binding to IGHM enhancer 3b [Source:ZFIN;Acc:ZDB-GENE-010919-3])

HSP 1 Score: 72.4034 bits (176), Expect = 5.616e-13
Identity = 52/123 (42.28%), Postives = 68/123 (55.28%), Query Frame = 1

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRK----RNQELENQIKTYYSNTTNSIDSQNLATNYHNYLL 1074
            K+R KK++HN IER+RR  IN +I ELG LIP   ++D E + NKG ILK SV+Y+ +L+ E        KE EM    LE   +    R QELE Q + +  N T S      A+   N LL
Sbjct:  264 KERQKKDNHNLIERRRRFNINDRIKELGALIPK--STDPEMRWNKGTILKASVDYIRKLQKE----QQRAKEIEMRQKKLEQSNQALILRIQELEIQARHHGLNATVSPGLNTEASFIQNQLL 380

[Close]

BLAST of mitfl-1 protein vs. Ensembl Zebrafish
Match: tfe3b (transcription factor binding to IGHM enhancer 3b [Source:ZFIN;Acc:ZDB-GENE-010919-3])

HSP 1 Score: 72.0182 bits (175), Expect = 7.155e-13
Identity = 52/123 (42.28%), Postives = 68/123 (55.28%), Query Frame = 1

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRK----RNQELENQIKTYYSNTTNSIDSQNLATNYHNYLL 1074
            K+R KK++HN IER+RR  IN +I ELG LIP   ++D E + NKG ILK SV+Y+ +L+ E        KE EM    LE   +    R QELE Q + +  N T S      A+   N LL
Sbjct:  276 KERQKKDNHNLIERRRRFNINDRIKELGALIPK--STDPEMRWNKGTILKASVDYIRKLQKE----QQRAKEIEMRQKKLEQSNQALILRIQELEIQARHHGLNATVSPGLNTEASFIQNQLL 392

[Close]

BLAST of mitfl-1 protein vs. Ensembl Zebrafish
Match: tfe3b (transcription factor binding to IGHM enhancer 3b [Source:ZFIN;Acc:ZDB-GENE-010919-3])

HSP 1 Score: 71.633 bits (174), Expect = 9.381e-13
Identity = 48/108 (44.44%), Postives = 63/108 (58.33%), Query Frame = 1

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRK----RNQELENQIKTYYSNTTNS 1029
            K+R KK++HN IER+RR  IN +I ELG LIP   ++D E + NKG ILK SV+Y+ +L+ E        KE EM    LE   +    R QELE Q + +  N T S
Sbjct:  217 KERQKKDNHNLIERRRRFNINDRIKELGALIPK--STDPEMRWNKGTILKASVDYIRKLQKE----QQRAKEIEMRQKKLEQSNQALILRIQELEIQARHHGLNATVS 318

[Close]

BLAST of mitfl-1 protein vs. Ensembl Xenopus
Match: ipo9 (importin 9 [Source:Xenbase;Acc:XB-GENE-5960761])

HSP 1 Score: 66.2402 bits (160), Expect = 8.733e-11
Identity = 72/244 (29.51%), Postives = 114/244 (46.72%), Query Frame = 1

Query:  298 YCESYTNNPTNVHFNQDMANNCFDVDDFIALESNYHRRNDSPYIVSPACQYDKYNILQYSSDYV-IDSKQDLPMQYRDNTSKSLLQPYEVLNNKNDISLSCPVTGERSEVSMNHAMSSCNFPPTPSSSVQGQYQNDNLKN-QKDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNE---FNNISNYVKETEMA--FMLLETYRKRNQELENQIKTY 1008
            Y  +  +N T+++F   M +    +DD I+LES+Y   N+   ++ P+ Q    N L  S + + I   Q +P             P  +     ++S SCP                 N P      ++ ++     +   K+R KK++HN IER+RR  IN +I ELG LIP   ++D + + NKG ILK SV+Y+ +L+ E      + N  K+ E A   +LL     R QELE Q + +
Sbjct:  195 YAAAAWHNGTDMYFALQMDDV---IDDIISLESSY---NEDILLMDPSMQM--ANTLPVSGNMIDIYGNQGMP-------------PPGL-----NVSNSCPA----------------NLP-----HIKREFTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPK--SNDPDMRWNKGTILKASVDYIRKLQREQQRSKEVENKQKKLEHANRHLLL-----RIQELEMQARAH 384

[Close]

BLAST of mitfl-1 protein vs. Ensembl Xenopus
Match: ipo9 (importin 9 [Source:Xenbase;Acc:XB-GENE-5960761])

HSP 1 Score: 65.0846 bits (157), Expect = 1.393e-10
Identity = 45/115 (39.13%), Postives = 67/115 (58.26%), Query Frame = 1

Query:  679 VQGQYQNDNLKNQKDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNE---FNNISNYVKETEMA--FMLLETYRKRNQELENQIKTY 1008
            + G  +++     K+R KK++HN IER+RR  IN +I ELG LIP   ++D + + NKG ILK SV+Y+ +L+ E      + N  K+ E A   +LL     R QELE Q + +
Sbjct:  224 IYGNQESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPK--SNDPDMRWNKGTILKASVDYIRKLQREQQRSKEVENKQKKLEHANRHLLL-----RIQELEMQARAH 331

[Close]

BLAST of mitfl-1 protein vs. Ensembl Xenopus
Match: ipo9 (importin 9 [Source:Xenbase;Acc:XB-GENE-5960761])

HSP 1 Score: 65.0846 bits (157), Expect = 1.613e-10
Identity = 45/115 (39.13%), Postives = 67/115 (58.26%), Query Frame = 1

Query:  679 VQGQYQNDNLKNQKDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNE---FNNISNYVKETEMA--FMLLETYRKRNQELENQIKTY 1008
            + G  +++     K+R KK++HN IER+RR  IN +I ELG LIP   ++D + + NKG ILK SV+Y+ +L+ E      + N  K+ E A   +LL     R QELE Q + +
Sbjct:  223 IYGNQESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPK--SNDPDMRWNKGTILKASVDYIRKLQREQQRSKEVENKQKKLEHANRHLLL-----RIQELEMQARAH 330

[Close]

BLAST of mitfl-1 protein vs. Ensembl Xenopus
Match: ipo9 (importin 9 [Source:Xenbase;Acc:XB-GENE-5960761])

HSP 1 Score: 65.0846 bits (157), Expect = 1.769e-10
Identity = 44/102 (43.14%), Postives = 62/102 (60.78%), Query Frame = 1

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNE---FNNISNYVKETEMA--FMLLETYRKRNQELENQIKTY 1008
            K+R KK++HN IER+RR  IN +I ELG LIP   ++D + + NKG ILK SV+Y+ +L+ E      + N  K+ E A   +LL     R QELE Q + +
Sbjct:  265 KERQKKDNHNLIERRRRFNINDRIKELGTLIPK--SNDPDMRWNKGTILKASVDYIRKLQREQQRSKEVENKQKKLEHANRHLLL-----RIQELEMQARAH 359

[Close]

BLAST of mitfl-1 protein vs. Ensembl Xenopus
Match: ipo9 (importin 9 [Source:Xenbase;Acc:XB-GENE-5960761])

HSP 1 Score: 64.3142 bits (155), Expect = 2.135e-10
Identity = 44/102 (43.14%), Postives = 62/102 (60.78%), Query Frame = 1

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNE---FNNISNYVKETEMA--FMLLETYRKRNQELENQIKTY 1008
            K+R KK++HN IER+RR  IN +I ELG LIP   ++D + + NKG ILK SV+Y+ +L+ E      + N  K+ E A   +LL     R QELE Q + +
Sbjct:  148 KERQKKDNHNLIERRRRFNINDRIKELGTLIPK--SNDPDMRWNKGTILKASVDYIRKLQREQQRSKEVENKQKKLEHANRHLLL-----RIQELEMQARAH 242

[Close]

BLAST of mitfl-1 protein vs. Ensembl Mouse
Match: Mitf (melanogenesis associated transcription factor [Source:MGI Symbol;Acc:MGI:104554])

HSP 1 Score: 71.2478 bits (173), Expect = 1.438e-12
Identity = 69/219 (31.51%), Postives = 108/219 (49.32%), Query Frame = 1

Query:  370 VDDFIALESNYHRRNDSPYIVSPACQYDKYNILQYSSDYV-IDSKQDLPMQYRDNTSKSLLQPYEVLNNKNDISLSCPVTGERSEVSMNHAMSSCNFPPTPSSSVQGQYQNDNLKNQKDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNE---FNNISNYVKETEMA--FMLLETYRKRNQELENQIKTY 1008
            +DD I+LES+Y+   +   ++ PA Q    N L  S + + + S Q LP             P   ++N      SCP        ++   +++C FP           +++     K+R KK++HN IER+RR  IN +I ELG LIP   ++D + + NKG ILK SV+Y+ +L+ E     ++ N  K+ E A   +LL     R QELE Q + +
Sbjct:  211 IDDIISLESSYN--EEILGLMDPALQM--ANTLPVSGNLIDLYSNQGLP------------PPGLTISN------SCPANLP----NIKRELTACIFP----------TESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPK--SNDPDMRWNKGTILKASVDYIRKLQREQQRAKDLENRQKKLEHANRHLLL-----RVQELEMQARAH 386

[Close]

BLAST of mitfl-1 protein vs. Ensembl Mouse
Match: Mitf (melanogenesis associated transcription factor [Source:MGI Symbol;Acc:MGI:104554])

HSP 1 Score: 71.2478 bits (173), Expect = 1.522e-12
Identity = 69/219 (31.51%), Postives = 107/219 (48.86%), Query Frame = 1

Query:  370 VDDFIALESNYHRRNDSPYIVSPACQYDKYNILQYSSDYV-IDSKQDLPMQYRDNTSKSLLQPYEVLNNKNDISLSCPVTGERSEVSMNHAMSSCNFPPTPSSSVQGQYQNDNLKNQKDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNE---FNNISNYVKETEMA--FMLLETYRKRNQELENQIKTY 1008
            +DD I+LES+Y+       ++ PA Q    N L  S + + + S Q LP             P   ++N      SCP        ++   +++C FP           +++     K+R KK++HN IER+RR  IN +I ELG LIP   ++D + + NKG ILK SV+Y+ +L+ E     ++ N  K+ E A   +LL     R QELE Q + +
Sbjct:  202 IDDIISLESSYNEEILG--LMDPALQM--ANTLPVSGNLIDLYSNQGLP------------PPGLTISN------SCPANLP----NIKRELTACIFP----------TESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPK--SNDPDMRWNKGTILKASVDYIRKLQREQQRAKDLENRQKKLEHANRHLLL-----RVQELEMQARAH 377

[Close]

BLAST of mitfl-1 protein vs. Ensembl Mouse
Match: Mitf (melanogenesis associated transcription factor [Source:MGI Symbol;Acc:MGI:104554])

HSP 1 Score: 71.2478 bits (173), Expect = 1.642e-12
Identity = 69/219 (31.51%), Postives = 107/219 (48.86%), Query Frame = 1

Query:  370 VDDFIALESNYHRRNDSPYIVSPACQYDKYNILQYSSDYV-IDSKQDLPMQYRDNTSKSLLQPYEVLNNKNDISLSCPVTGERSEVSMNHAMSSCNFPPTPSSSVQGQYQNDNLKNQKDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNE---FNNISNYVKETEMA--FMLLETYRKRNQELENQIKTY 1008
            +DD I+LES+Y+       ++ PA Q    N L  S + + + S Q LP             P   ++N      SCP        ++   +++C FP           +++     K+R KK++HN IER+RR  IN +I ELG LIP   ++D + + NKG ILK SV+Y+ +L+ E     ++ N  K+ E A   +LL     R QELE Q + +
Sbjct:  227 IDDIISLESSYNEEILG--LMDPALQM--ANTLPVSGNLIDLYSNQGLP------------PPGLTISN------SCPANLP----NIKRELTACIFP----------TESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPK--SNDPDMRWNKGTILKASVDYIRKLQREQQRAKDLENRQKKLEHANRHLLL-----RVQELEMQARAH 402

[Close]

BLAST of mitfl-1 protein vs. Ensembl Mouse
Match: Mitf (melanogenesis associated transcription factor [Source:MGI Symbol;Acc:MGI:104554])

HSP 1 Score: 70.4774 bits (171), Expect = 1.795e-12
Identity = 69/219 (31.51%), Postives = 108/219 (49.32%), Query Frame = 1

Query:  370 VDDFIALESNYHRRNDSPYIVSPACQYDKYNILQYSSDYV-IDSKQDLPMQYRDNTSKSLLQPYEVLNNKNDISLSCPVTGERSEVSMNHAMSSCNFPPTPSSSVQGQYQNDNLKNQKDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNE---FNNISNYVKETEMA--FMLLETYRKRNQELENQIKTY 1008
            +DD I+LES+Y+   +   ++ PA Q    N L  S + + + S Q LP             P   ++N      SCP        ++   +++C FP           +++     K+R KK++HN IER+RR  IN +I ELG LIP   ++D + + NKG ILK SV+Y+ +L+ E     ++ N  K+ E A   +LL     R QELE Q + +
Sbjct:  120 IDDIISLESSYNE--EILGLMDPALQM--ANTLPVSGNLIDLYSNQGLP------------PPGLTISN------SCPANLP----NIKRELTACIFP----------TESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPK--SNDPDMRWNKGTILKASVDYIRKLQREQQRAKDLENRQKKLEHANRHLLL-----RVQELEMQARAH 295

[Close]

BLAST of mitfl-1 protein vs. Ensembl Mouse
Match: Tfeb (transcription factor EB [Source:MGI Symbol;Acc:MGI:103270])

HSP 1 Score: 67.0106 bits (162), Expect = 1.741e-11
Identity = 43/106 (40.57%), Postives = 62/106 (58.49%), Query Frame = 1

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNN---ISNYVKETEMAFMLLETYRKRNQELENQIKTYYSNTTN 1026
            K+R KK++HN IER+RR  IN +I ELG LIP    +D + + NKG ILK SV+Y+ R++ +      + N+ +  EM    L     R QELE Q + +   TT+
Sbjct:   90 KERQKKDNHNLIERRRRFNINDRIKELGMLIPKA--NDLDVRWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWL---RIQELEMQARVHGLPTTS 190

[Close]

BLAST of mitfl-1 protein vs. UniProt/SwissProt
Match: sp|Q08874|MITF_MOUSE (Microphthalmia-associated transcription factor OS=Mus musculus OX=10090 GN=Mitf PE=1 SV=4)

HSP 1 Score: 71.2478 bits (173), Expect = 1.148e-11
Identity = 69/219 (31.51%), Postives = 107/219 (48.86%), Query Frame = 1

Query:  370 VDDFIALESNYHRRNDSPYIVSPACQYDKYNILQYSSDYV-IDSKQDLPMQYRDNTSKSLLQPYEVLNNKNDISLSCPVTGERSEVSMNHAMSSCNFPPTPSSSVQGQYQNDNLKNQKDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNE---FNNISNYVKETEMA--FMLLETYRKRNQELENQIKTY 1008
            +DD I+LES+Y+       ++ PA Q    N L  S + + + S Q LP             P   ++N      SCP        ++   +++C FP           +++     K+R KK++HN IER+RR  IN +I ELG LIP   ++D + + NKG ILK SV+Y+ +L+ E     ++ N  K+ E A   +LL     R QELE Q + +
Sbjct:  227 IDDIISLESSYNEEILG--LMDPALQM--ANTLPVSGNLIDLYSNQGLP------------PPGLTISN------SCPANLP----NIKRELTACIFP----------TESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPK--SNDPDMRWNKGTILKASVDYIRKLQREQQRAKDLENRQKKLEHANRHLLL-----RVQELEMQARAH 402

[Close]

BLAST of mitfl-1 protein vs. UniProt/SwissProt
Match: sp|O88368|MITF_RAT (Microphthalmia-associated transcription factor OS=Rattus norvegicus OX=10116 GN=Mitf PE=2 SV=2)

HSP 1 Score: 71.2478 bits (173), Expect = 1.189e-11
Identity = 69/219 (31.51%), Postives = 107/219 (48.86%), Query Frame = 1

Query:  370 VDDFIALESNYHRRNDSPYIVSPACQYDKYNILQYSSDYV-IDSKQDLPMQYRDNTSKSLLQPYEVLNNKNDISLSCPVTGERSEVSMNHAMSSCNFPPTPSSSVQGQYQNDNLKNQKDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNE---FNNISNYVKETEMA--FMLLETYRKRNQELENQIKTY 1008
            +DD I+LES+Y+       ++ PA Q    N L  S + + + S Q LP             P   ++N      SCP        ++   +++C FP           +++     K+R KK++HN IER+RR  IN +I ELG LIP   ++D + + NKG ILK SV+Y+ +L+ E     ++ N  K+ E A   +LL     R QELE Q + +
Sbjct:  227 IDDIISLESSYNEEILG--LMDPALQM--ANTLPVSGNLIDLYSNQGLP------------PPGLTISN------SCPANLP----NIKRELTACIFP----------TESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPK--SNDPDMRWNKGTILKASVDYIRKLQREQQRAKDLENRQKKLEHANRHLLL-----RVQELEMQARAH 402

[Close]

BLAST of mitfl-1 protein vs. UniProt/SwissProt
Match: sp|O75030|MITF_HUMAN (Microphthalmia-associated transcription factor OS=Homo sapiens OX=9606 GN=MITF PE=1 SV=2)

HSP 1 Score: 69.3218 bits (168), Expect = 5.254e-11
Identity = 68/219 (31.05%), Postives = 106/219 (48.40%), Query Frame = 1

Query:  370 VDDFIALESNYHRRNDSPYIVSPACQYDKYNILQYSSDYV-IDSKQDLPMQYRDNTSKSLLQPYEVLNNKNDISLSCPVTGERSEVSMNHAMSSCNFPPTPSSSVQGQYQNDNLKNQKDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNE---FNNISNYVKETEMA--FMLLETYRKRNQELENQIKTY 1008
            +DD I+LES+Y+       ++ PA Q    N L  S + + +   Q LP             P   ++N      SCP     +  ++   +++C FP           +++     K+R KK++HN IER+RR  IN +I ELG LIP   ++D + + NKG ILK SV+Y+ +L+ E      + N  K+ E A   +LL     R QELE Q + +
Sbjct:  227 IDDIISLESSYNEEILG--LMDPALQM--ANTLPVSGNLIDLYGNQGLP------------PPGLTISN------SCPA----NLPNIKRELTACIFP----------TESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPK--SNDPDMRWNKGTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLL-----RIQELEMQARAH 402

[Close]

BLAST of mitfl-1 protein vs. UniProt/SwissProt
Match: sp|P19484|TFEB_HUMAN (Transcription factor EB OS=Homo sapiens OX=9606 GN=TFEB PE=1 SV=3)

HSP 1 Score: 67.781 bits (164), Expect = 1.448e-10
Identity = 46/114 (40.35%), Postives = 65/114 (57.02%), Query Frame = 1

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNN---ISNYVKETEMAFMLLETYRKRNQELENQIKTYYSNTTNSIDSQNLA 1050
            K+R KK++HN IER+RR  IN +I ELG LIP    +D + + NKG ILK SV+Y+ R++ +      + N+ +  EM    L     R QELE Q + +   TT S    N+A
Sbjct:  232 KERQKKDNHNLIERRRRFNINDRIKELGMLIPKA--NDLDVRWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWL---RIQELEMQARVHGLPTT-SPSGMNMA 339

[Close]

BLAST of mitfl-1 protein vs. UniProt/SwissProt
Match: sp|Q9R210|TFEB_MOUSE (Transcription factor EB OS=Mus musculus OX=10090 GN=Tfeb PE=1 SV=2)

HSP 1 Score: 67.3958 bits (163), Expect = 1.577e-10
Identity = 43/106 (40.57%), Postives = 62/106 (58.49%), Query Frame = 1

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNN---ISNYVKETEMAFMLLETYRKRNQELENQIKTYYSNTTN 1026
            K+R KK++HN IER+RR  IN +I ELG LIP    +D + + NKG ILK SV+Y+ R++ +      + N+ +  EM    L     R QELE Q + +   TT+
Sbjct:  231 KERQKKDNHNLIERRRRFNINDRIKELGMLIPKA--NDLDVRWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWL---RIQELEMQARVHGLPTTS 331

[Close]

BLAST of mitfl-1 protein vs. TrEMBL
Match: U5YQ80 (Mitfl-1 protein (Fragment) OS=Schmidtea mediterranea OX=79327 GN=mitfl-1 PE=2 SV=1)

HSP 1 Score: 732.25 bits (1889), Expect = 0.000e+0
Identity = 359/360 (99.72%), Postives = 359/360 (99.72%), Query Frame = 1

Query:  385 ALESNYHRRNDSPYIVSPACQYDKYNILQYSSDYVIDSKQDLPMQYRDNTSKSLLQPYEVLNNKNDISLSCPVTGERSEVSMNHAMSSCNFPPTPSSSVQGQYQNDNLKNQKDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRKRNQELENQIKTYYSNTTNSIDSQNLATNYHNYLLLHEQNQKIYQSNGKQMYLKNTKPIITDINRRLGPMKDKQLSPLENQIAFKIEPSSAHSSGGNNSLSTTYRIEEEVDPQFNLSHELINIQNAYQITNNNHPSLPSMHNDSYFSSNTHFRCMDNQKYESMEC 1464
            ALESNYHRRNDSPYIVSPACQYDKYNILQYSSDYVIDSKQDLPMQYRDNTSKSLLQPYEVLNNKNDISLSCPVTGERSEVSMNHAMSSCNFPPTPSSSVQGQYQNDNLKNQKDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRKRNQELENQIKTYYSNTTNSIDSQNLATNYHNYLLLHEQN KIYQSNGKQMYLKNTKPIITDINRRLGPMKDKQLSPLENQIAFKIEPSSAHSSGGNNSLSTTYRIEEEVDPQFNLSHELINIQNAYQITNNNHPSLPSMHNDSYFSSNTHFRCMDNQKYESMEC
Sbjct:    1 ALESNYHRRNDSPYIVSPACQYDKYNILQYSSDYVIDSKQDLPMQYRDNTSKSLLQPYEVLNNKNDISLSCPVTGERSEVSMNHAMSSCNFPPTPSSSVQGQYQNDNLKNQKDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRKRNQELENQIKTYYSNTTNSIDSQNLATNYHNYLLLHEQNPKIYQSNGKQMYLKNTKPIITDINRRLGPMKDKQLSPLENQIAFKIEPSSAHSSGGNNSLSTTYRIEEEVDPQFNLSHELINIQNAYQITNNNHPSLPSMHNDSYFSSNTHFRCMDNQKYESMEC 360

[Close]

BLAST of mitfl-1 protein vs. TrEMBL
Match: A0A183MKH1 (BHLH domain-containing protein OS=Schistosoma margrebowiei OX=48269 GN=SMRZ_LOCUS16546 PE=4 SV=1)

HSP 1 Score: 122.094 bits (305), Expect = 4.076e-25
Identity = 94/274 (34.31%), Postives = 135/274 (49.27%), Query Frame = 1

Query:  364 FDVDDFIALESNYHRRNDSPYIVSPACQYDKYNILQYSSDYVIDSKQDLPMQYRDNTSKSLLQ-----PYEVLNNKNDISLSCPVTGERSEVSMNHAMSSCNFPPTPSSSVQGQYQNDN-LKNQKDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRKRNQELEN-----QIKTYYSNTTNSIDSQNLATNYHNYLLLHEQNQKIYQSNGKQMYLKNTKPIIT 1152
             D++ F   ES    R+D+   VS +C            D         P+Q     ++S+L      P   LN+          T E + + ++H   S     +P+S   G+  +D  +   +DR+KK+SHNRIERKRRDYIN QI ELG L+P +M  D + KKNKGNILKNSVE++  L++E   I    +ET +A  ++    KR QELE+      ++T ++N  N  D QNL   Y  + +LHE N            L N+ PI T
Sbjct:  312 VDMNPFFMKESTKVNRDDTGMTVSSSCPAT------VPDDLCTTDNNTSPLQSGSRAAQSVLSESGSSPLGGLNS----------TPEATSLPVSHGPLSIGNISSPTS---GRNIDDQRVAWMRDRSKKDSHNRIERKRRDYINCQIAELGSLLPEDMFRDGDGKKNKGNILKNSVEFICLLRSELAQIPEVRRETSLAAKVIGQLVKRIQELESVTNVASMQTSHTNRNNP-DYQNL---YQEWSILHENN------------LLNSVPICT 550

[Close]

BLAST of mitfl-1 protein vs. TrEMBL
Match: A0A430QBX1 (BHLH domain-containing protein OS=Schistosoma bovis OX=6184 GN=DC041_0012560 PE=4 SV=1)

HSP 1 Score: 120.939 bits (302), Expect = 8.484e-25
Identity = 89/254 (35.04%), Postives = 128/254 (50.39%), Query Frame = 1

Query:  364 FDVDDFIALESNYHRRNDSPYIVSPACQYDKYNILQYSSDYVIDSKQDLPMQYRDNTSKSLLQ-----PYEVLNNKNDISLSCPVTGERSEVSMNHA-MSSCNFPPTPSSSVQGQYQNDN-LKNQKDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRKRNQELEN-----QIKTYYSNTTNSIDSQNLATNYHNYLLLHEQN 1089
             D++ F   ES    R+D+    S +C            D         P+Q     ++S+L      P   LN+          T E + + ++H  +S  N     SS   G+  +D  +   +DR+KK+SHNRIERKRRDYIN QI ELG L+P +M  D + KKNKGNILKNSVE++  L++E   I    +ET +A  ++    KR QELE+      ++T ++N  N  D QNL   Y  + +LHE N
Sbjct:  313 VDMNPFFMKESTKVNRDDTGMTASSSCPAT------VPDDLCTTDNNTSPLQSGSRAAQSVLSESGSSPLGGLNS----------TPEATSLPVSHGPLSIGNI----SSPTSGRNIDDQRVAWMRDRSKKDSHNRIERKRRDYINCQIAELGSLLPEDMFRDGDGKKNKGNILKNSVEFICLLRSELAQIPEVRRETSLAAKVIGQLVKRIQELESVTNVASMQTSHANRNNP-DYQNL---YQEWSILHENN 542

[Close]

BLAST of mitfl-1 protein vs. TrEMBL
Match: A0A183K1C9 (BHLH domain-containing protein OS=Schistosoma curassoni OX=6186 GN=SCUD_LOCUS8792 PE=4 SV=1)

HSP 1 Score: 120.553 bits (301), Expect = 9.862e-25
Identity = 89/254 (35.04%), Postives = 128/254 (50.39%), Query Frame = 1

Query:  364 FDVDDFIALESNYHRRNDSPYIVSPACQYDKYNILQYSSDYVIDSKQDLPMQYRDNTSKSLLQ-----PYEVLNNKNDISLSCPVTGERSEVSMNHA-MSSCNFPPTPSSSVQGQYQNDN-LKNQKDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRKRNQELEN-----QIKTYYSNTTNSIDSQNLATNYHNYLLLHEQN 1089
             D++ F   ES    R+D+    S +C            D         P+Q     ++S+L      P   LN+          T E + + ++H  +S  N     SS   G+  +D  +   +DR+KK+SHNRIERKRRDYIN QI ELG L+P +M  D + KKNKGNILKNSVE++  L++E   I    +ET +A  ++    KR QELE+      ++T ++N  N  D QNL   Y  + +LHE N
Sbjct:  218 VDMNPFFMKESTKVNRDDTGMTASSSCPAT------VPDDLCTTDNNTSPLQSGSRAAQSVLSESGSSPLGGLNS----------TPEATNLPVSHGPLSIGNI----SSPTSGRNIDDQRVAWMRDRSKKDSHNRIERKRRDYINCQIAELGSLLPEDMFRDGDGKKNKGNILKNSVEFICLLRSELAQIPEVRRETSLAAKVIGQLVKRIQELESVTNVASMQTSHANRNNP-DYQNL---YQEWSILHENN 447

[Close]

BLAST of mitfl-1 protein vs. TrEMBL
Match: A0A094ZW83 (Transcription factor EB OS=Schistosoma haematobium OX=6185 GN=MS3_05767 PE=4 SV=1)

HSP 1 Score: 120.553 bits (301), Expect = 1.537e-24
Identity = 93/274 (33.94%), Postives = 134/274 (48.91%), Query Frame = 1

Query:  364 FDVDDFIALESNYHRRNDSPYIVSPACQYDKYNILQYSSDYVIDSKQDLPMQYRDNTSKSLLQ-----PYEVLNNKNDISLSCPVTGERSEVSMNHAMSSCNFPPTPSSSVQGQYQNDN-LKNQKDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRKRNQELEN-----QIKTYYSNTTNSIDSQNLATNYHNYLLLHEQNQKIYQSNGKQMYLKNTKPIIT 1152
             D++ F   ES    R+D+    S +C            D         P+Q     ++S+L      P   LN+          T E + + ++H   S     +P+S   G+  +D  +   +DR+KK+SHNRIERKRRDYIN QI ELG L+P +M  D + KKNKGNILKNSVE++  L++E   I    +ET +A  ++    KR QELE+      ++T ++N  N  D QNL   Y  + +LHE N            L N+ PI T
Sbjct:  313 VDMNPFFMKESTKVNRDDTGMTASSSCPAT------VPDDLCTTDNNTSPLQSGSRAAQSVLSESGSSPLGGLNS----------TPEATSLPVSHGPLSIGNISSPTS---GRNIDDQRVAWMRDRSKKDSHNRIERKRRDYINCQIAELGSLLPEDMFRDGDGKKNKGNILKNSVEFICLLRSELAQIPEVRRETSLAAKVIGQLVKRIQELESVTNVASMQTSHANRNNP-DYQNL---YQEWSILHENN------------LLNSVPICT 551

[Close]

BLAST of mitfl-1 protein vs. Ensembl Cavefish
Match: tfe3a (transcription factor E3 [Source:NCBI gene;Acc:103028851])

HSP 1 Score: 71.2478 bits (173), Expect = 1.362e-12
Identity = 49/115 (42.61%), Postives = 67/115 (58.26%), Query Frame = 1

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSD-NESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLE----TYRKRNQELENQIKTYYSNTTNSIDSQNL 1047
            K+R KK++HN IER+RR  IN +I ELG L+P   +SD +E + NKG ILK SV+Y+ +L+ E     +  KE E+    LE    T   R QELE Q + +   +T   DS  L
Sbjct:  335 KERQKKDNHNLIERRRRFNINDRIKELGALVPK--SSDPSEMRWNKGTILKASVDYIRKLQKE----QHRAKEMELRQKKLEHANRTLLLRIQELEMQARVHGIASTQGSDSTLL 443

[Close]

BLAST of mitfl-1 protein vs. Ensembl Cavefish
Match: tfe3b (transcription factor binding to IGHM enhancer 3b [Source:ZFIN;Acc:ZDB-GENE-010919-3])

HSP 1 Score: 68.5514 bits (166), Expect = 8.209e-12
Identity = 44/99 (44.44%), Postives = 58/99 (58.59%), Query Frame = 1

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLE----TYRKRNQELENQIK 1002
            K+R KK++HN IER+RR  IN +I ELG LIP  +  D E + NKG ILK SV+Y+ +L+ E        KE +M    LE    +   R QELE Q +
Sbjct:  277 KERQKKDNHNLIERRRRFNINDRIKELGALIPKSV--DPEMRWNKGTILKASVDYIRKLQKE----QQRAKEVDMKQKKLEHANQSLLLRIQELEMQAR 369

[Close]

BLAST of mitfl-1 protein vs. Ensembl Cavefish
Match: tfeb (transcription factor EB [Source:NCBI gene;Acc:103036573])

HSP 1 Score: 66.6254 bits (161), Expect = 3.151e-11
Identity = 42/107 (39.25%), Postives = 62/107 (57.94%), Query Frame = 1

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRK----RNQELENQIKTYYSNTTN 1026
            K+R KK++HN IER+RR  IN +I ELG +IP    +D + + NKG IL+ SVEY+ R++ +        +E E  F  +E   K    R QELE Q + +   +T+
Sbjct:  222 KERQKKDNHNLIERRRRFNINDRIKELGTMIPK--TNDLDVRWNKGTILRASVEYIKRMQKDVQR----TREVENNFKRMEVANKQLWLRIQELEMQARLHGLPSTS 322

[Close]

BLAST of mitfl-1 protein vs. Ensembl Cavefish
Match: tfeb (transcription factor EB [Source:NCBI gene;Acc:103036573])

HSP 1 Score: 66.6254 bits (161), Expect = 3.379e-11
Identity = 42/107 (39.25%), Postives = 62/107 (57.94%), Query Frame = 1

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRK----RNQELENQIKTYYSNTTN 1026
            K+R KK++HN IER+RR  IN +I ELG +IP    +D + + NKG IL+ SVEY+ R++ +        +E E  F  +E   K    R QELE Q + +   +T+
Sbjct:  238 KERQKKDNHNLIERRRRFNINDRIKELGTMIPK--TNDLDVRWNKGTILRASVEYIKRMQKDVQR----TREVENNFKRMEVANKQLWLRIQELEMQARLHGLPSTS 338

[Close]

BLAST of mitfl-1 protein vs. Ensembl Cavefish
Match: mitfa (melanocyte inducing transcription factor a [Source:ZFIN;Acc:ZDB-GENE-990910-11])

HSP 1 Score: 62.3882 bits (150), Expect = 7.990e-10
Identity = 32/62 (51.61%), Postives = 45/62 (72.58%), Query Frame = 1

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNE 903
            K+R KK++HN IER+RR  IN +I ELG LIP   ++D + + NKG ILK SV+Y+ +L+ E
Sbjct:  185 KERQKKDNHNLIERRRRFNINDRIKELGTLIPK--SNDPDMRWNKGTILKASVDYIRKLQRE 244

[Close]

BLAST of mitfl-1 protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001124.1 (pep scaffold:Pmarinus_7.0:GL489212:1887:7231:1 gene:ENSPMAG00000001002.1 transcript:ENSPMAT00000001124.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 73.559 bits (179), Expect = 2.069e-14
Identity = 73/218 (33.49%), Postives = 96/218 (44.04%), Query Frame = 1

Query:  370 VDDFIALESNYHRRNDSPYIVSPACQYDKYNILQYSSDYVIDSKQDLPMQYRDNTSKSLLQPYEVLNNKNDISLSCP---------VTGERSEVSMNHAMSSCNFPPTPSSSVQGQYQNDNLKNQ------------KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLE 960
            +DD I+LES+Y   ND PY      + +  N L  SS             Y     ++L  P   L      S SCP         VTG  SE +  H       PP   S   GQY      +             K+R KK++HN IER+RR  IN +I ELG LIP   +SD +++ NKG ILK SV+Y+ R++ E        KE E+    LE
Sbjct:  144 IDDIISLESSY---NDEPY-TGIGARLEVTNTLPLSSSL-----------YDGYGGQTLAVPAVALT-----SSSCPATLDNVKQEVTGT-SEWACTHTRK--KDPPRMGSG--GQYHARQRHSGLFPAEVEARAIVKERQKKDNHNLIERRRRFNINDRIKELGTLIPK--SSDPDTRWNKGTILKASVDYIRRMQKE----QQRAKEMELRQRRLE 330

[Close]

BLAST of mitfl-1 protein vs. Ensembl Sea Lamprey
Match: mitfa (melanocyte inducing transcription factor a [Source:ZFIN;Acc:ZDB-GENE-990910-11])

HSP 1 Score: 67.0106 bits (162), Expect = 1.026e-12
Identity = 49/121 (40.50%), Postives = 66/121 (54.55%), Query Frame = 1

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRK----RNQELENQIKTY-------YSNTTNSIDSQNL 1047
            K+R KK++HN IER+RR  IN +I ELG LIP   ++D + + NKG ILK SV+Y+ RL+ E       VKE E     LE   +    R QELE Q + +          TT  ++ Q L
Sbjct:    9 KERQKKDNHNLIERRRRFNINDRIKELGTLIPK--SNDPDMRWNKGTILKASVDYIRRLQKE----QQRVKEMENRQRRLEQTNRGLIMRMQELEMQARAHGLPSSSPTGLTTGDLNGQQL 123

[Close]

BLAST of mitfl-1 protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001122.1 (pep scaffold:Pmarinus_7.0:GL489212:1806:7231:1 gene:ENSPMAG00000001002.1 transcript:ENSPMAT00000001122.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 65.855 bits (159), Expect = 6.772e-12
Identity = 38/81 (46.91%), Postives = 52/81 (64.20%), Query Frame = 1

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLE 960
            K+R KK++HN IER+RR  IN +I ELG LIP   +SD +++ NKG ILK SV+Y+ R++ E        KE E+    LE
Sbjct:  270 KERQKKDNHNLIERRRRFNINDRIKELGTLIPK--SSDPDTRWNKGTILKASVDYIRRMQKE----QQRAKEMELRQRRLE 344

[Close]

BLAST of mitfl-1 protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009530.1 (pep scaffold:Pmarinus_7.0:GL478885:25441:30908:1 gene:ENSPMAG00000008619.1 transcript:ENSPMAT00000009530.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 60.4622 bits (145), Expect = 2.525e-11
Identity = 44/97 (45.36%), Postives = 56/97 (57.73%), Query Frame = 1

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRK----RNQELENQ 996
            K+R KKESHN IER+RR  IN +I ELG LI    +SD + + NKG ILK SV+Y+ RL+ +        ++ E    LLE        R QELE Q
Sbjct:    9 KERRKKESHNLIERRRRFNINDRIKELGALITK--SSDPDIRWNKGTILKASVDYIRRLQRD----QQRSRDMETRQRLLEEANAILGLRIQELERQ 99

[Close]

BLAST of mitfl-1 protein vs. Ensembl Sea Lamprey
Match: USF2 (upstream transcription factor 2, c-fos interacting [Source:HGNC Symbol;Acc:HGNC:12594])

HSP 1 Score: 61.2326 bits (147), Expect = 6.256e-11
Identity = 31/93 (33.33%), Postives = 52/93 (55.91%), Query Frame = 1

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRKRNQELENQ 996
            +D  ++  HN +ER+RRD IN+ I EL K IP   N   +S ++KG +L  + EY+  L+     +   +KE E   +  E   ++ +EL+N+
Sbjct:  106 RDERRRAQHNEVERRRRDKINNWIVELSKYIPDCANDHTKSVQSKGGVLSKACEYIQELRQTNQRMEEELKEAERTQLEHELLMQQFEELKNE 198

[Close]

BLAST of mitfl-1 protein vs. Ensembl Yeast
Match: RTG3 (bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways; forms a complex with another bHLH/Zip protein, Rtg1p, to activate the pathways; target of Hog1p [Source:SGD;Acc:S000000199])

HSP 1 Score: 54.299 bits (129), Expect = 2.884e-8
Identity = 30/65 (46.15%), Postives = 44/65 (67.69%), Query Frame = 1

Query:  712 NQKDRNKKESHNRIERKRRDYINHQITELGKLI-PSEMNSDNESKK---NKGNILKNSVEYVTRL 894
            ++K R K+E HN +ER+RR+ I  +I ELG+L+ PS +N D+  K+   NKG IL  +VEY+  L
Sbjct:  280 DEKLRRKREFHNAVERRRRELIKQKIKELGQLVPPSLLNYDDLGKQIKPNKGIILDRTVEYLQYL 344

[Close]

BLAST of mitfl-1 protein vs. Ensembl Nematostella
Match: EDO44411 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RVM3])

HSP 1 Score: 70.8626 bits (172), Expect = 4.406e-13
Identity = 41/102 (40.20%), Postives = 60/102 (58.82%), Query Frame = 1

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRKRNQELENQIKTYYSNTT 1023
            +DR KK++HN IER+RR  IN +I ELG ++P +   D +S++NKG ILK SV+Y+  LK + + +    +E     ML      R QELE   + +   TT
Sbjct:  273 RDRQKKDNHNMIERRRRFNINDRIKELGTMLPKQ---DPDSRQNKGTILKASVDYIRNLKKDVDKMKLIEEEKRQLEMLNRKLLLRVQELEMHARAHGIPTT 371

[Close]

BLAST of mitfl-1 protein vs. Ensembl Nematostella
Match: EDO39334 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SAA2])

HSP 1 Score: 68.1662 bits (165), Expect = 8.428e-13
Identity = 39/151 (25.83%), Postives = 76/151 (50.33%), Query Frame = 1

Query:  544 LLQPYEVLNNKNDISLSCPVTGERSEVSMNHAMSSCNFPPTPSSSVQGQYQNDNLKNQKDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRKRNQELENQ 996
            +L  + V+ +  D+  S P   +RS     H + S    P               +  +D  ++ +HN +ER+RRD IN  IT+L K++P   +   ++ ++KG IL  +V+Y+T L+     ++  +K++E   +  E  R++N+E+  +
Sbjct:   85 VLGGFYVMMSPQDVMQSGP-GAQRSIAPRTHQLGSKLEGP---------------RGARDEKRRATHNEVERRRRDKINGWITKLAKVVPDCSSDQTKTGQSKGGILAKTVDYITDLRAANARMAETIKDSEQLAIDNELLRQQNEEVRQE 219

[Close]

BLAST of mitfl-1 protein vs. Ensembl Nematostella
Match: EDO28110 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T7E1])

HSP 1 Score: 63.929 bits (154), Expect = 3.524e-12
Identity = 33/119 (27.73%), Postives = 67/119 (56.30%), Query Frame = 1

Query:  640 MSSCNFPPTPSSSVQGQYQNDNLKNQKDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRKRNQELENQ 996
            M  C +  +  S ++G       +  +D  ++ +HN +ER+RRD IN  IT+L K++P   +   ++ ++KG IL  +V+Y+T L+     ++  +K++E   +  E  R++N+E+  +
Sbjct:    1 MIKCKYYCSHCSKLEGP------RGARDEKRRATHNEVERRRRDKINGWITKLAKVVPDCSSDQTKTGQSKGGILAKTVDYITDLRAANARMAETIKDSEQLAIDNELLRQQNEEVRQE 113

[Close]

BLAST of mitfl-1 protein vs. Ensembl Nematostella
Match: EDO34999 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SMU2])

HSP 1 Score: 51.9878 bits (123), Expect = 4.631e-7
Identity = 30/73 (41.10%), Postives = 42/73 (57.53%), Query Frame = 1

Query:  676 SVQGQYQNDNLKNQKDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKK-NKGNILKNSVEYVTR 891
            SV   + N +   +K  N + SH  IE++RRD IN  ++EL +LIPS  N    S K  K  IL+ +VEYV +
Sbjct:   28 SVTESFDNTSFSGKKKANSECSHKVIEKRRRDRINSCLSELAQLIPSAQNGKQGSGKLEKAEILELTVEYVKK 100

[Close]

BLAST of mitfl-1 protein vs. Ensembl Medaka
Match: ENSORLT00000031443.1 (transcription factor E3 [Source:NCBI gene;Acc:101174799])

HSP 1 Score: 74.3294 bits (181), Expect = 1.177e-13
Identity = 48/115 (41.74%), Postives = 69/115 (60.00%), Query Frame = 1

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNE---FNNISNYVKETEMA--FMLLETYRKRNQELENQIKTYYSNTTNSIDSQNL 1047
            KDR KK +HN IER+RR  IN +I ELG LIP   +SD E++ NKG ILK SV+Y+ +L+ +     ++    K+ E    F+LL     R QELE Q + +   +++S+D Q  
Sbjct:  249 KDRQKKNNHNLIERRRRFNINDRIKELGVLIPK--SSDMEARWNKGTILKASVDYIRKLQKDQQRARDLEERQKKLESTNRFLLL-----RIQELEQQARQHGLLSSSSVDPQTF 356

[Close]

BLAST of mitfl-1 protein vs. Ensembl Medaka
Match: mitfa (microphthalmia-associated transcription factor-like [Source:NCBI gene;Acc:101163732])

HSP 1 Score: 67.3958 bits (163), Expect = 1.121e-11
Identity = 59/179 (32.96%), Postives = 89/179 (49.72%), Query Frame = 1

Query:  598 PVTGERSEVSMNHAMSSCNFPPTPS--SSVQGQYQNDNLKN-QKDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRK----RNQELENQIKTY---YSNTTNSIDSQNLATNYHNYLLLHEQNQKIYQ 1104
            PV+    +V  N  ++  N P + S  S ++ +     ++   K+R KK++HN IER+RR  IN +I ELG LIP   ++D + + NKG ILK SV+Y+ +L+ E        KE E     LE        R QELE Q + +    +   +   S+ LA       +L E   +IYQ
Sbjct:  116 PVSSSLIDVYNNQGLTLSNLPTSSSCASGIKRELTETEVRALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPK--SNDPDMRWNKGTILKASVDYIRKLQQE----QQRTKELECRHKKLEHANSHLMLRIQELEIQARAHGLTVAAAPSICTSELLARAIKQEPILGECPPEIYQ 288

[Close]

BLAST of mitfl-1 protein vs. Ensembl Medaka
Match: usf2 (upstream stimulatory factor 2 [Source:NCBI gene;Acc:101164660])

HSP 1 Score: 65.0846 bits (157), Expect = 2.584e-11
Identity = 34/92 (36.96%), Postives = 53/92 (57.61%), Query Frame = 1

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRKRNQELEN 993
            +D  ++  HN +ER+RRD IN+ I  L KLIP + + D+ S  +KG IL  + +Y+  L+     +    KE E A M  E  R++ +EL+N
Sbjct:  149 RDERRRAQHNEVERRRRDKINNWIVTLSKLIP-DCSVDSRSAASKGGILSKACDYIRELRQNNQRLQESCKEVEQAEMDNELLRQQVEELKN 239

[Close]

BLAST of mitfl-1 protein vs. Ensembl Medaka
Match: tfe3b (transcription factor binding to IGHM enhancer 3 [Source:NCBI gene;Acc:101166296])

HSP 1 Score: 67.0106 bits (162), Expect = 2.917e-11
Identity = 45/110 (40.91%), Postives = 64/110 (58.18%), Query Frame = 1

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNE---FNNISNYVKETEMAFMLLETYRKRNQELENQIKTYYSNTTNSIDS 1038
            K+R KK++HN IER+RR  IN +I ELG LIP   +SD   + NKG ILK SV+Y+ +L+ E     ++    K+ E A  +L     R QELE Q + +  +T   I +
Sbjct:  276 KERQKKDNHNLIERRRRFNINDRIKELGTLIPK--SSDPYMRWNKGTILKASVDYIRKLQKEQQRAKDVEVRQKKLEQANHILML---RIQELEMQARLHGLSTPAGISA 380

[Close]

BLAST of mitfl-1 protein vs. Ensembl Medaka
Match: MITF (microphthalmia-associated transcription factor [Source:NCBI gene;Acc:101165733])

HSP 1 Score: 66.2402 bits (160), Expect = 3.089e-11
Identity = 46/110 (41.82%), Postives = 64/110 (58.18%), Query Frame = 1

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNE---FNNISNYVKETEMA---FMLLETYRKRNQELENQIKTYYSNTTNS 1029
            K+R KK++HN IER+RR  IN +I ELG LIP   ++D + + NKG ILK SV+Y+ +L+ E      + N  K+ E A    ML      R QELE Q + +    T+S
Sbjct:  194 KERQKKDNHNLIERRRRFNINDRIKELGTLIPK--SNDPDMRWNKGTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLML------RIQELEMQARAHGLPITSS 295

[Close]

BLAST of mitfl-1 protein vs. Planmine SMEST
Match: SMESG000051880.1 (SMESG000051880.1)

HSP 1 Score: 870.152 bits (2247), Expect = 0.000e+0
Identity = 454/457 (99.34%), Postives = 455/457 (99.56%), Query Frame = 1

Query:   94 MSSRIKLRQEIERMKVMEEEXXXXXXXXXXXXXXFRNTLKSGNELLSFDNTYLPSLSXXXXXXXXXXDYCESYTNNPTNVHFNQDMANNCFDVDDFIALESNYHRRNDSPYIVSPACQYDKYNILQYSSDYVIDSKQDLPMQYRDNTSKSLLQPYEVLNNKNDISLSCPVTGERSEVSMNHAMSSCNFPPTPSSSVQGQYQNDNLKNQKDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRKRNQELENQIKTYYSNTTNSIDSQNLATNYHNYLLLHEQNQKIYQSNGKQMYLKNTKPIITDINRRLGPMKDKQLSPLENQIAFKIEPSSAHSSGGNNSLSTTYRIEEEVDPQFNLSHELINIQNAYQITNNNHPSLPSMHNDSYFSSNTHFRCMDNQKYESMEC 1464
            MSSRIKLRQEIERMKVMEEEKSQNNGNGKSQNNNFRNTLKSGNELLSFDNTYLPSLSYPINNINPNYDYCESYTNNPTNVHFNQDMANNCFDVDDFIALESNYHRRNDSPYIVSPACQYDKYNILQYSSDYVIDSKQDL MQYRDNTSKSLLQPYEVLNNKNDISLSCPVTGERSEVSMNHAMSSCNFPPTPSSSVQGQYQNDNLKNQKDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRKRNQELENQIKTYYS TTNSIDSQNLATNYHNYLLLHEQNQKIYQSNGKQMYLKNTKPIITDINRRLGPMKDKQLSPLENQIAFKIEPSSAHSSGGNNSLSTTYRIEEEVDPQFNLSHE+INIQNAYQITNNNHPSLPSMHNDSYFSSNTHFRCMDNQKYESMEC
Sbjct:    1 MSSRIKLRQEIERMKVMEEEKSQNNGNGKSQNNNFRNTLKSGNELLSFDNTYLPSLSYPINNINPNYDYCESYTNNPTNVHFNQDMANNCFDVDDFIALESNYHRRNDSPYIVSPACQYDKYNILQYSSDYVIDSKQDLSMQYRDNTSKSLLQPYEVLNNKNDISLSCPVTGERSEVSMNHAMSSCNFPPTPSSSVQGQYQNDNLKNQKDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRKRNQELENQIKTYYSTTTNSIDSQNLATNYHNYLLLHEQNQKIYQSNGKQMYLKNTKPIITDINRRLGPMKDKQLSPLENQIAFKIEPSSAHSSGGNNSLSTTYRIEEEVDPQFNLSHEMINIQNAYQITNNNHPSLPSMHNDSYFSSNTHFRCMDNQKYESMEC 457

[Close]

BLAST of mitfl-1 protein vs. Planmine SMEST
Match: SMESG000051880.1 (SMESG000051880.1)

HSP 1 Score: 844.343 bits (2180), Expect = 0.000e+0
Identity = 441/444 (99.32%), Postives = 442/444 (99.55%), Query Frame = 1

Query:  133 MKVMEEEXXXXXXXXXXXXXXFRNTLKSGNELLSFDNTYLPSLSXXXXXXXXXXDYCESYTNNPTNVHFNQDMANNCFDVDDFIALESNYHRRNDSPYIVSPACQYDKYNILQYSSDYVIDSKQDLPMQYRDNTSKSLLQPYEVLNNKNDISLSCPVTGERSEVSMNHAMSSCNFPPTPSSSVQGQYQNDNLKNQKDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRKRNQELENQIKTYYSNTTNSIDSQNLATNYHNYLLLHEQNQKIYQSNGKQMYLKNTKPIITDINRRLGPMKDKQLSPLENQIAFKIEPSSAHSSGGNNSLSTTYRIEEEVDPQFNLSHELINIQNAYQITNNNHPSLPSMHNDSYFSSNTHFRCMDNQKYESMEC 1464
            MKVMEEEKSQNNGNGKSQNNNFRNTLKSGNELLSFDNTYLPSLSYPINNINPNYDYCESYTNNPTNVHFNQDMANNCFDVDDFIALESNYHRRNDSPYIVSPACQYDKYNILQYSSDYVIDSKQDL MQYRDNTSKSLLQPYEVLNNKNDISLSCPVTGERSEVSMNHAMSSCNFPPTPSSSVQGQYQNDNLKNQKDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRKRNQELENQIKTYYS TTNSIDSQNLATNYHNYLLLHEQNQKIYQSNGKQMYLKNTKPIITDINRRLGPMKDKQLSPLENQIAFKIEPSSAHSSGGNNSLSTTYRIEEEVDPQFNLSHE+INIQNAYQITNNNHPSLPSMHNDSYFSSNTHFRCMDNQKYESMEC
Sbjct:    1 MKVMEEEKSQNNGNGKSQNNNFRNTLKSGNELLSFDNTYLPSLSYPINNINPNYDYCESYTNNPTNVHFNQDMANNCFDVDDFIALESNYHRRNDSPYIVSPACQYDKYNILQYSSDYVIDSKQDLSMQYRDNTSKSLLQPYEVLNNKNDISLSCPVTGERSEVSMNHAMSSCNFPPTPSSSVQGQYQNDNLKNQKDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRKRNQELENQIKTYYSTTTNSIDSQNLATNYHNYLLLHEQNQKIYQSNGKQMYLKNTKPIITDINRRLGPMKDKQLSPLENQIAFKIEPSSAHSSGGNNSLSTTYRIEEEVDPQFNLSHEMINIQNAYQITNNNHPSLPSMHNDSYFSSNTHFRCMDNQKYESMEC 444

[Close]

BLAST of mitfl-1 protein vs. Planmine SMEST
Match: SMESG000077129.1 (SMESG000077129.1)

HSP 1 Score: 100.138 bits (248), Expect = 8.414e-22
Identity = 59/154 (38.31%), Postives = 94/154 (61.04%), Query Frame = 1

Query:  643 SSCNFPPTPSSSVQGQYQNDNLKNQKDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRKRNQELENQIKTYYSNTTNSIDSQNLATNYHNYLLLHEQNQKIYQ 1104
            S+ N P   ++   G  +   L+  +DRNKK+ HNRIERKRRDYIN+QI ELG+L+P ++    ESK+NKG ILKNSV Y+ +L+   + I +  KE +++  L+  + K  Q L++ +K+   N   +I+ +NL   + +   +H+ N  + Q
Sbjct:  209 SANNTPQIVTTIPSGLPEEQKLQWVRDRNKKDCHNRIERKRRDYINNQIQELGQLLPEKLFLSTESKRNKGGILKNSVIYIQQLQESISCIQHLQKEAQISENLITVFYKHIQYLQDLLKSNGVNYEQNINDKNLLQEWFD---IHQTNSHLLQ 359

[Close]

BLAST of mitfl-1 protein vs. Planmine SMEST
Match: SMESG000009137.1 (SMESG000009137.1)

HSP 1 Score: 77.411 bits (189), Expect = 6.985e-15
Identity = 36/60 (60.00%), Postives = 49/60 (81.67%), Query Frame = 1

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLK 897
            KD++KKE+HNR+ERKRRD+IN QI +L +L+P+E   + + K NKG ILKNSVEY+T +K
Sbjct:   93 KDKHKKETHNRVERKRRDFINCQIQKLAELLPTEFFLNCDLKMNKGVILKNSVEYITSMK 152

[Close]

BLAST of mitfl-1 protein vs. Planmine SMEST
Match: SMESG000009137.1 (SMESG000009137.1)

HSP 1 Score: 77.411 bits (189), Expect = 7.161e-15
Identity = 36/60 (60.00%), Postives = 49/60 (81.67%), Query Frame = 1

Query:  718 KDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESKKNKGNILKNSVEYVTRLK 897
            KD++KKE+HNR+ERKRRD+IN QI +L +L+P+E   + + K NKG ILKNSVEY+T +K
Sbjct:   85 KDKHKKETHNRVERKRRDFINCQIQKLAELLPTEFFLNCDLKMNKGVILKNSVEYITSMK 144

The following BLAST results are available for this feature:

BLAST of mitfl-1 protein vs. Ensembl Human
BLAST of mitfl-1 protein vs. Ensembl Celegans
BLAST of mitfl-1 protein vs. Ensembl Fly
BLAST of mitfl-1 protein vs. Ensembl Zebrafish
BLAST of mitfl-1 protein vs. Ensembl Xenopus
BLAST of mitfl-1 protein vs. Ensembl Mouse
BLAST of mitfl-1 protein vs. UniProt/SwissProt
BLAST of mitfl-1 protein vs. TrEMBL
BLAST of mitfl-1 protein vs. Ensembl Cavefish
BLAST of mitfl-1 protein vs. Ensembl Sea Lamprey
BLAST of mitfl-1 protein vs. Ensembl Yeast
BLAST of mitfl-1 protein vs. Ensembl Nematostella
BLAST of mitfl-1 protein vs. Ensembl Medaka
BLAST of mitfl-1 protein vs. Planmine SMEST

BLAST of mitfl-1 protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
MITF	1.094e-11	31.05	melanocyte inducing transcription factor [Source:H...	[more]
MITF	1.411e-11	31.05	melanocyte inducing transcription factor [Source:H...	[more]
TFEB	2.102e-11	40.35	transcription factor EB [Source:HGNC Symbol;Acc:HG...	[more]
TFEB	2.194e-11	40.35	transcription factor EB [Source:HGNC Symbol;Acc:HG...	[more]
TFEB	2.787e-11	40.35	transcription factor EB [Source:HGNC Symbol;Acc:HG...	[more]

BLAST of mitfl-1 protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
hlh-30	8.812e-9	36.17	Helix Loop Helix [Source:UniProtKB/TrEMBL;Acc:Q86...	[more]
hlh-30	8.812e-9	36.17	Helix Loop Helix [Source:UniProtKB/TrEMBL;Acc:Q86...	[more]
hlh-30	1.037e-8	36.17	Helix Loop Helix [Source:UniProtKB/TrEMBL;Acc:Q86...	[more]
hlh-30	1.065e-8	36.17	Helix Loop Helix [Source:UniProtKB/TrEMBL;Acc:Q86...	[more]
hlh-30	1.232e-8	36.17	Helix Loop Helix [Source:UniProtKB/TrEMBL;Acc:Q86...	[more]

BLAST of mitfl-1 protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4


Match Name	E-value	Identity	Description
Mitf	1.273e-9	39.22	gene:FBgn0263112 transcript:FBtr0307328	[more]
Mitf	1.283e-9	38.61	gene:FBgn0263112 transcript:FBtr0307326	[more]
Mitf	1.283e-9	38.61	gene:FBgn0263112 transcript:FBtr0307327	[more]
Mitf	1.293e-9	38.61	gene:FBgn0263112 transcript:FBtr0307329	[more]

BLAST of mitfl-1 protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tfe3b	3.648e-13	42.28	transcription factor binding to IGHM enhancer 3b [...	[more]
tfe3b	3.648e-13	42.28	transcription factor binding to IGHM enhancer 3b [...	[more]
tfe3b	5.616e-13	42.28	transcription factor binding to IGHM enhancer 3b [...	[more]
tfe3b	7.155e-13	42.28	transcription factor binding to IGHM enhancer 3b [...	[more]
tfe3b	9.381e-13	44.44	transcription factor binding to IGHM enhancer 3b [...	[more]

BLAST of mitfl-1 protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ipo9	8.733e-11	29.51	importin 9 [Source:Xenbase;Acc:XB-GENE-5960761]	[more]
ipo9	1.393e-10	39.13	importin 9 [Source:Xenbase;Acc:XB-GENE-5960761]	[more]
ipo9	1.613e-10	39.13	importin 9 [Source:Xenbase;Acc:XB-GENE-5960761]	[more]
ipo9	1.769e-10	43.14	importin 9 [Source:Xenbase;Acc:XB-GENE-5960761]	[more]
ipo9	2.135e-10	43.14	importin 9 [Source:Xenbase;Acc:XB-GENE-5960761]	[more]

BLAST of mitfl-1 protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Mitf	1.438e-12	31.51	melanogenesis associated transcription factor [Sou...	[more]
Mitf	1.522e-12	31.51	melanogenesis associated transcription factor [Sou...	[more]
Mitf	1.642e-12	31.51	melanogenesis associated transcription factor [Sou...	[more]
Mitf	1.795e-12	31.51	melanogenesis associated transcription factor [Sou...	[more]
Tfeb	1.741e-11	40.57	transcription factor EB [Source:MGI Symbol;Acc:MGI...	[more]

BLAST of mitfl-1 protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q08874\|MITF_MOUSE	1.148e-11	31.51	Microphthalmia-associated transcription factor OS=...	[more]
sp\|O88368\|MITF_RAT	1.189e-11	31.51	Microphthalmia-associated transcription factor OS=...	[more]
sp\|O75030\|MITF_HUMAN	5.254e-11	31.05	Microphthalmia-associated transcription factor OS=...	[more]
sp\|P19484\|TFEB_HUMAN	1.448e-10	40.35	Transcription factor EB OS=Homo sapiens OX=9606 GN...	[more]
sp\|Q9R210\|TFEB_MOUSE	1.577e-10	40.57	Transcription factor EB OS=Mus musculus OX=10090 G...	[more]

BLAST of mitfl-1 protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
U5YQ80	0.000e+0	99.72	Mitfl-1 protein (Fragment) OS=Schmidtea mediterran...	[more]
A0A183MKH1	4.076e-25	34.31	BHLH domain-containing protein OS=Schistosoma marg...	[more]
A0A430QBX1	8.484e-25	35.04	BHLH domain-containing protein OS=Schistosoma bovi...	[more]
A0A183K1C9	9.862e-25	35.04	BHLH domain-containing protein OS=Schistosoma cura...	[more]
A0A094ZW83	1.537e-24	33.94	Transcription factor EB OS=Schistosoma haematobium...	[more]

BLAST of mitfl-1 protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tfe3a	1.362e-12	42.61	transcription factor E3 [Source:NCBI gene;Acc:1030...	[more]
tfe3b	8.209e-12	44.44	transcription factor binding to IGHM enhancer 3b [...	[more]
tfeb	3.151e-11	39.25	transcription factor EB [Source:NCBI gene;Acc:1030...	[more]
tfeb	3.379e-11	39.25	transcription factor EB [Source:NCBI gene;Acc:1030...	[more]
mitfa	7.990e-10	51.61	melanocyte inducing transcription factor a [Source...	[more]

BLAST of mitfl-1 protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000001124.1	2.069e-14	33.49	pep scaffold:Pmarinus_7.0:GL489212:1887:7231:1 gen...	[more]
mitfa	1.026e-12	40.50	melanocyte inducing transcription factor a [Source...	[more]
ENSPMAT00000001122.1	6.772e-12	46.91	pep scaffold:Pmarinus_7.0:GL489212:1806:7231:1 gen...	[more]
ENSPMAT00000009530.1	2.525e-11	45.36	pep scaffold:Pmarinus_7.0:GL478885:25441:30908:1 g...	[more]
USF2	6.256e-11	33.33	upstream transcription factor 2, c-fos interacting...	[more]

BLAST of mitfl-1 protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
RTG3	2.884e-8	46.15	bHLH/Zip transcription factor for retrograde (RTG)...	[more]

BLAST of mitfl-1 protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4


Match Name	E-value	Identity	Description
EDO44411	4.406e-13	40.20	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO39334	8.428e-13	25.83	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO28110	3.524e-12	27.73	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO34999	4.631e-7	41.10	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of mitfl-1 protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSORLT00000031443.1	1.177e-13	41.74	transcription factor E3 [Source:NCBI gene;Acc:1011...	[more]
mitfa	1.121e-11	32.96	microphthalmia-associated transcription factor-lik...	[more]
usf2	2.584e-11	36.96	upstream stimulatory factor 2 [Source:NCBI gene;Ac...	[more]
tfe3b	2.917e-11	40.91	transcription factor binding to IGHM enhancer 3 [S...	[more]
MITF	3.089e-11	41.82	microphthalmia-associated transcription factor [So...	[more]

BLAST of mitfl-1 protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000051880.1	0.000e+0	99.34	SMESG000051880.1	[more]
SMESG000051880.1	0.000e+0	99.32	SMESG000051880.1	[more]
SMESG000077129.1	8.414e-22	38.31	SMESG000077129.1	[more]
SMESG000009137.1	6.985e-15	60.00	SMESG000009137.1	[more]
SMESG000009137.1	7.161e-15	60.00	SMESG000009137.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Cross References

External references for this transcript


Database	Accession
SmedGD GBrowse	SMED30020410
GenBank	AGZ94932.1

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30020410 ID=SMED30020410|Name=mitfl-1 protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1818bp
CATAATTCAAATAATTTTTTAATTAATTTTTATTACTTCTAAAGTGAATT
TTGCTAATTATAAATACATTTTTATAACAGTTGCTTTTGCAAAATGAGTT
CTCGAATAAAATTGCGACAAGAAATAGAACGCATGAAAGTTATGGAAGAA
GAAAAATCACAAAATAATGGAAACGGTAAATCACAAAATAATAATTTCCG
AAATACTTTAAAAAGTGGAAACGAATTATTATCTTTTGATAATACTTATC
TTCCGAGTTTAAGTTACCCAATTAACAATATTAATCCAAATTATGATTAC
TGTGAATCCTATACAAACAATCCAACTAATGTTCACTTTAATCAAGATAT
GGCAAATAATTGCTTTGATGTGGATGACTTTATTGCACTCGAAAGCAATT
ATCACAGGAGAAACGACTCACCTTATATAGTTTCCCCAGCATGCCAATAT
GATAAATACAATATTTTACAGTACAGCAGTGATTACGTGATTGACAGTAA
ACAAGATTTACCTATGCAATACCGAGATAATACCAGCAAAAGCCTTCTTC
AACCTTATGAAGTACTTAATAATAAAAACGATATTTCCCTTTCATGTCCT
GTAACCGGTGAACGGTCAGAGGTCAGTATGAATCATGCAATGAGTAGTTG
TAATTTCCCACCAACTCCATCGTCGTCAGTACAGGGTCAATATCAAAATG
ACAACCTCAAAAATCAAAAAGACCGTAACAAAAAAGAAAGCCATAATAGA
ATCGAAAGAAAGCGACGTGATTATATTAATCATCAAATAACCGAATTGGG
TAAATTGATTCCCTCAGAAATGAATTCCGACAATGAATCCAAGAAAAACA
AAGGAAATATCCTAAAAAATTCAGTGGAATATGTGACCCGATTGAAAAAT
GAATTTAATAATATTTCCAATTATGTTAAAGAAACAGAAATGGCATTTAT
GTTACTGGAGACTTATCGAAAAAGAAATCAGGAACTGGAAAATCAAATAA
AAACCTATTACTCTAATACCACAAACTCTATTGACAGTCAAAATCTGGCG
ACGAATTATCATAACTACCTGTTATTACACGAGCAAAATCAGAAAATTTA
TCAGTCCAACGGAAAACAAATGTACTTAAAGAATACTAAACCAATTATTA
CAGACATAAATCGTCGGTTAGGTCCGATGAAAGATAAACAGCTTTCTCCT
TTGGAAAATCAAATTGCATTTAAAATTGAGCCGAGTTCTGCACATTCTTC
CGGTGGAAATAATTCGCTTTCAACTACCTATCGGATTGAAGAAGAAGTTG
ATCCTCAATTCAATCTATCCCATGAATTGATTAATATACAAAATGCTTAT
CAGATCACAAATAATAATCATCCGTCCTTGCCGTCCATGCACAATGACTC
GTATTTCAGTTCCAACACTCACTTTCGGTGCATGGACAATCAAAAATATG
AATCAATGGAATGTTAGCCAATTAATCAGCGCATCTTGACATTTTCTAAT
AACAATCAGCATGTACAATTTAGTTTTTAATCGGAAAGATTTAATGTTTT
TAATGCTCTGCGTGCTTGAATTTATAGAAAACCCTCATTTTTACAAGTGC
CTTATAAGCGTTCTTTAGATTTGATTATTGATTATTACATTTTTGATTTT
TTTAAAGATTTTATTGAGTGAAATGTGTTGAAAATTTGTAACTAGGTGCA
TAAGATGAATATATTGATTTACCGTTTACTTTCATATCATATGATCTTAT
TGATTTCATATTTTTATAATTCAATATATATTAATTTTGGTAAATAAATC
GATTATCAGTTGTCAAAA

protein sequence of SMED30020410-orf-1

>SMED30020410-orf-1 ID=SMED30020410-orf-1|Name=SMED30020410-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=458bp
MSSRIKLRQEIERMKVMEEEKSQNNGNGKSQNNNFRNTLKSGNELLSFDN
TYLPSLSYPINNINPNYDYCESYTNNPTNVHFNQDMANNCFDVDDFIALE
SNYHRRNDSPYIVSPACQYDKYNILQYSSDYVIDSKQDLPMQYRDNTSKS
LLQPYEVLNNKNDISLSCPVTGERSEVSMNHAMSSCNFPPTPSSSVQGQY
QNDNLKNQKDRNKKESHNRIERKRRDYINHQITELGKLIPSEMNSDNESK
KNKGNILKNSVEYVTRLKNEFNNISNYVKETEMAFMLLETYRKRNQELEN
QIKTYYSNTTNSIDSQNLATNYHNYLLLHEQNQKIYQSNGKQMYLKNTKP
IITDINRRLGPMKDKQLSPLENQIAFKIEPSSAHSSGGNNSLSTTYRIEE
EVDPQFNLSHELINIQNAYQITNNNHPSLPSMHNDSYFSSNTHFRCMDNQ
KYESMEC*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000026	gut
PLANA:0000034	epidermis
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036638	HLH_DNA-bd_sf
IPR011598	bHLH_dom

Vocabulary: **molecular function**
Term	Definition
GO:0046983	protein dimerization activity

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 288..308
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 190..205
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 206..223
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 190..223
None	No IPR available	PANTHER	PTHR45776	FAMILY NOT NAMED	coord: 1..440
IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain	SMART	SM00353	finulus	coord: 218..273 e-value: 3.2E-7 score: 40.0
IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain	PFAM	PF00010	HLH	coord: 213..267 e-value: 1.6E-11 score: 44.0
IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain	PROSITE	PS50888	BHLH	coord: 212..267 score: 13.814
IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain	CDD	cd00083	HLH	coord: 210..270 e-value: 9.44349E-10 score: 52.2163
IPR036638	Helix-loop-helix DNA-binding domain superfamily	GENE3D	G3DSA:4.10.280.10		coord: 209..271 e-value: 4.1E-19 score: 70.3
IPR036638	Helix-loop-helix DNA-binding domain superfamily	SUPERFAMILY	SSF47459	HLH, helix-loop-helix DNA-binding domain	coord: 210..271