WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2

Overview


Name	WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2
Smed ID	SMED30020397
Length (bp)	323

Neoblast Clusters

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30020397

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 8

Expressed In	Reference Transcript	Published Transcript	Transcriptome	Publication
Smed sexual biotype	SMED30020397	Contig32141	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020397	Contig32141	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020397	Contig55339	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020397	Contig55339	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
epidermis	SMED30020397	dd_Smed_v4_1268_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
tail region	SMED30020397	dd_Smed_v6_1268_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
whole organism	SMED30020397	Contig32141	uc_Smed_v2	PMID:27612384 Roberts-Galbraith et al., 2016
whole organism	SMED30020397	Contig32141	newmark_ests	PMID:27612384 Roberts-Galbraith et al., 2016

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Human
Match: WFIKKN2 (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30916])

HSP 1 Score: 79.7221 bits (195), Expect = 2.933e-18
Identity = 34/63 (53.97%), Postives = 47/63 (74.60%), Query Frame = 3

Query:   33 CVFENISCLNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            C+   +S   + CSLP   GPCKAY PR+ YNS+TG+C+ F+YGGC+GN NNF+S + CE++C
Sbjct:  281 CMLACMSGPLAACSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESC 343

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Human
Match: WFIKKN2 (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30916])

HSP 1 Score: 78.9518 bits (193), Expect = 6.908e-18
Identity = 34/63 (53.97%), Postives = 47/63 (74.60%), Query Frame = 3

Query:   33 CVFENISCLNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            C+   +S   + CSLP   GPCKAY PR+ YNS+TG+C+ F+YGGC+GN NNF+S + CE++C
Sbjct:  374 CMLACMSGPLAACSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESC 436

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Human
Match: TFPI (tissue factor pathway inhibitor [Source:HGNC Symbol;Acc:HGNC:11760])

HSP 1 Score: 66.2402 bits (160), Expect = 6.178e-15
Identity = 26/60 (43.33%), Postives = 43/60 (71.67%), Query Frame = 3

Query:   48 ISCLNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCHK 227
            +  ++S C+   + GPCKA   R+++N  T +CE+FIYGGC+GNQN F+S ++C++ C +
Sbjct:   47 LKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTR 106

[Close]

Query:   48 ISCLNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCHK 227
            +  ++S C+   + GPCKA   R+++N  T +CE+FIYGGC+GNQN F+S ++C++ C +
Sbjct:   47 LKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTR 106

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Human
Match: TFPI (tissue factor pathway inhibitor [Source:HGNC Symbol;Acc:HGNC:11760])

HSP 1 Score: 66.2402 bits (160), Expect = 6.792e-15
Identity = 26/58 (44.83%), Postives = 42/58 (72.41%), Query Frame = 3

Query:   48 ISCLNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            +  ++S C+   + GPCKA   R+++N  T +CE+FIYGGC+GNQN F+S ++C++ C
Sbjct:   47 LKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC 104

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667211:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3d.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 70.4774 bits (171), Expect = 2.140e-15
Identity = 26/52 (50.00%), Postives = 38/52 (73.08%), Query Frame = 3

Query:   66 ICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            +C++P +AG C  Y PR+++NS+TG+CE+F YG C GN+NNF     CE+ C
Sbjct: 2167 VCAMPPDAGVCTNYTPRWFFNSQTGQCEQFAYGSCGGNENNFFDRNTCERKC 2218

HSP 2 Score: 69.707 bits (169), Expect = 4.890e-15
Identity = 27/51 (52.94%), Postives = 36/51 (70.59%), Query Frame = 3

Query:   69 CSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            CSLPK  GPC  Y  R+Y+N+   +C+ F +GGC+GNQNNF+  +DCE  C
Sbjct:  539 CSLPKERGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCESAC 589

HSP 3 Score: 60.8474 bits (146), Expect = 6.340e-12
Identity = 26/50 (52.00%), Postives = 32/50 (64.00%), Query Frame = 3

Query:   72 SLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            SLP   GPC   F RY+YN  + KCE+F Y GC GN NN++S + CE  C
Sbjct:  427 SLP---GPCHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACEDRC 473

HSP 4 Score: 60.077 bits (144), Expect = 1.125e-11
Identity = 24/53 (45.28%), Postives = 33/53 (62.26%), Query Frame = 3

Query:   69 CSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCHK 227
            C  P   GPCK +  R+Y+N   G C  F YGGC GN+N+F + K+CE +C +
Sbjct: 1074 CLQPVEPGPCKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECEVHCAR 1126

HSP 5 Score: 56.6102 bits (135), Expect = 1.648e-10
Identity = 21/53 (39.62%), Postives = 34/53 (64.15%), Query Frame = 3

Query:   69 CSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCHK 227
            C  P+++G C+  F R++++ +   C+ F Y GC+GN NNF S ++C   CHK
Sbjct:  728 CLHPRDSGNCRGQFVRWFFDDEKKNCDVFTYTGCQGNGNNFASKEECMAICHK 780

HSP 6 Score: 53.5286 bits (127), Expect = 1.968e-9
Identity = 24/54 (44.44%), Postives = 30/54 (55.56%), Query Frame = 3

Query:   60 NSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            N +C  P   G C+    RYYY+  T  C  F Y GC GN NNF S +DC++ C
Sbjct: 2730 NPLCIQPVVKGSCQEAHLRYYYDRVTDSCRLFEYSGCDGNANNFGSLEDCQRLC 2783

HSP 7 Score: 50.8322 bits (120), Expect = 1.825e-8
Identity = 20/51 (39.22%), Postives = 33/51 (64.71%), Query Frame = 3

Query:   69 CSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            CS  K++G  K Y  ++Y+N K  +CE+F++ G  GN N F++  +CE+ C
Sbjct: 2232 CSFDKDSGSGKGYNVKWYFNMKNLRCEQFVFEGLGGNTNQFETLSECERIC 2282

HSP 8 Score: 47.7506 bits (112), Expect = 1.995e-7
Identity = 18/53 (33.96%), Postives = 25/53 (47.17%), Query Frame = 3

Query:   63 SICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            + C      G C   F R+ ++     C  F YGGC GN NNF + ++C   C
Sbjct:  855 ATCEADIEVGECAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKC 907

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667211:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 70.4774 bits (171), Expect = 2.161e-15
Identity = 26/52 (50.00%), Postives = 38/52 (73.08%), Query Frame = 3

Query:   66 ICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            +C++P +AG C  Y PR+++NS+TG+CE+F YG C GN+NNF     CE+ C
Sbjct: 2176 VCAMPPDAGVCTNYTPRWFFNSQTGQCEQFAYGSCGGNENNFFDRNTCERKC 2227

HSP 2 Score: 69.707 bits (169), Expect = 4.890e-15
Identity = 27/51 (52.94%), Postives = 36/51 (70.59%), Query Frame = 3

Query:   69 CSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            CSLPK  GPC  Y  R+Y+N+   +C+ F +GGC+GNQNNF+  +DCE  C
Sbjct:  539 CSLPKERGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCESAC 589

HSP 3 Score: 60.8474 bits (146), Expect = 6.402e-12
Identity = 26/50 (52.00%), Postives = 32/50 (64.00%), Query Frame = 3

Query:   72 SLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            SLP   GPC   F RY+YN  + KCE+F Y GC GN NN++S + CE  C
Sbjct:  427 SLP---GPCHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACEDRC 473

HSP 4 Score: 60.077 bits (144), Expect = 1.136e-11
Identity = 24/53 (45.28%), Postives = 33/53 (62.26%), Query Frame = 3

Query:   69 CSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCHK 227
            C  P   GPCK +  R+Y+N   G C  F YGGC GN+N+F + K+CE +C +
Sbjct: 1083 CLQPVEPGPCKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECEVHCAR 1135

HSP 5 Score: 56.6102 bits (135), Expect = 1.665e-10
Identity = 21/53 (39.62%), Postives = 34/53 (64.15%), Query Frame = 3

Query:   69 CSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCHK 227
            C  P+++G C+  F R++++ +   C+ F Y GC+GN NNF S ++C   CHK
Sbjct:  737 CLHPRDSGNCRGQFVRWFFDDEKKNCDVFTYTGCQGNGNNFASKEECMAICHK 789

HSP 6 Score: 53.5286 bits (127), Expect = 2.007e-9
Identity = 24/54 (44.44%), Postives = 30/54 (55.56%), Query Frame = 3

Query:   60 NSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            N +C  P   G C+    RYYY+  T  C  F Y GC GN NNF S +DC++ C
Sbjct: 2739 NPLCIQPVVKGSCQEAHLRYYYDRVTDSCRLFEYSGCDGNANNFGSLEDCQRLC 2792

HSP 7 Score: 50.8322 bits (120), Expect = 1.861e-8
Identity = 20/51 (39.22%), Postives = 33/51 (64.71%), Query Frame = 3

Query:   69 CSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            CS  K++G  K Y  ++Y+N K  +CE+F++ G  GN N F++  +CE+ C
Sbjct: 2241 CSFDKDSGSGKGYNVKWYFNMKNLRCEQFVFEGLGGNTNQFETLSECERIC 2291

HSP 8 Score: 47.7506 bits (112), Expect = 2.034e-7
Identity = 18/53 (33.96%), Postives = 25/53 (47.17%), Query Frame = 3

Query:   63 SICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            + C      G C   F R+ ++     C  F YGGC GN NNF + ++C   C
Sbjct:  864 ATCEADIEVGECAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKC 916

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667209:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3c.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 70.4774 bits (171), Expect = 2.474e-15
Identity = 26/52 (50.00%), Postives = 38/52 (73.08%), Query Frame = 3

Query:   66 ICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            +C++P +AG C  Y PR+++NS+TG+CE+F YG C GN+NNF     CE+ C
Sbjct: 2047 VCAMPPDAGVCTNYTPRWFFNSQTGQCEQFAYGSCGGNENNFFDRNTCERKC 2098

HSP 2 Score: 69.3218 bits (168), Expect = 5.545e-15
Identity = 27/51 (52.94%), Postives = 36/51 (70.59%), Query Frame = 3

Query:   69 CSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            CSLPK  GPC  Y  R+Y+N+   +C+ F +GGC+GNQNNF+  +DCE  C
Sbjct:  410 CSLPKERGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCESAC 460

HSP 3 Score: 60.4622 bits (145), Expect = 7.331e-12
Identity = 26/50 (52.00%), Postives = 32/50 (64.00%), Query Frame = 3

Query:   72 SLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            SLP   GPC   F RY+YN  + KCE+F Y GC GN NN++S + CE  C
Sbjct:  298 SLP---GPCHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACEDRC 344

HSP 4 Score: 59.6918 bits (143), Expect = 1.239e-11
Identity = 24/53 (45.28%), Postives = 33/53 (62.26%), Query Frame = 3

Query:   69 CSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCHK 227
            C  P   GPCK +  R+Y+N   G C  F YGGC GN+N+F + K+CE +C +
Sbjct:  954 CLQPVEPGPCKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECEVHCAR 1006

HSP 5 Score: 56.6102 bits (135), Expect = 1.851e-10
Identity = 21/53 (39.62%), Postives = 34/53 (64.15%), Query Frame = 3

Query:   69 CSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCHK 227
            C  P+++G C+  F R++++ +   C+ F Y GC+GN NNF S ++C   CHK
Sbjct:  608 CLHPRDSGNCRGQFVRWFFDDEKKNCDVFTYTGCQGNGNNFASKEECMAICHK 660

HSP 6 Score: 53.5286 bits (127), Expect = 2.211e-9
Identity = 24/54 (44.44%), Postives = 30/54 (55.56%), Query Frame = 3

Query:   60 NSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            N +C  P   G C+    RYYY+  T  C  F Y GC GN NNF S +DC++ C
Sbjct: 2610 NPLCIQPVVKGSCQEAHLRYYYDRVTDSCRLFEYSGCDGNANNFGSLEDCQRLC 2663

HSP 7 Score: 50.8322 bits (120), Expect = 2.049e-8
Identity = 20/51 (39.22%), Postives = 33/51 (64.71%), Query Frame = 3

Query:   69 CSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            CS  K++G  K Y  ++Y+N K  +CE+F++ G  GN N F++  +CE+ C
Sbjct: 2112 CSFDKDSGSGKGYNVKWYFNMKNLRCEQFVFEGLGGNTNQFETLSECERIC 2162

HSP 8 Score: 47.7506 bits (112), Expect = 2.197e-7
Identity = 18/53 (33.96%), Postives = 25/53 (47.17%), Query Frame = 3

Query:   63 SICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            + C      G C   F R+ ++     C  F YGGC GN NNF + ++C   C
Sbjct:  735 ATCEADIEVGECAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKC 787

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667209:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3h.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 68.9366 bits (167), Expect = 7.116e-15
Identity = 26/52 (50.00%), Postives = 38/52 (73.08%), Query Frame = 3

Query:   66 ICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            +C++P +AG C  Y PR+++NS+TG+CE+F YG C GN+NNF     CE+ C
Sbjct: 1574 VCAMPPDAGVCTNYTPRWFFNSQTGQCEQFAYGSCGGNENNFFDRNTCERKC 1625

HSP 2 Score: 68.1662 bits (165), Expect = 1.519e-14
Identity = 27/51 (52.94%), Postives = 36/51 (70.59%), Query Frame = 3

Query:   69 CSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            CSLPK  GPC  Y  R+Y+N+   +C+ F +GGC+GNQNNF+  +DCE  C
Sbjct:  318 CSLPKERGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCESAC 368

HSP 3 Score: 59.3066 bits (142), Expect = 1.970e-11
Identity = 26/50 (52.00%), Postives = 32/50 (64.00%), Query Frame = 3

Query:   72 SLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            SLP   GPC   F RY+YN  + KCE+F Y GC GN NN++S + CE  C
Sbjct:  206 SLP---GPCHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACEDRC 252

HSP 4 Score: 58.9214 bits (141), Expect = 3.052e-11
Identity = 24/53 (45.28%), Postives = 33/53 (62.26%), Query Frame = 3

Query:   69 CSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCHK 227
            C  P   GPCK +  R+Y+N   G C  F YGGC GN+N+F + K+CE +C +
Sbjct:  862 CLQPVEPGPCKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECEVHCAR 914

HSP 5 Score: 55.4546 bits (132), Expect = 4.096e-10
Identity = 21/53 (39.62%), Postives = 34/53 (64.15%), Query Frame = 3

Query:   69 CSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCHK 227
            C  P+++G C+  F R++++ +   C+ F Y GC+GN NNF S ++C   CHK
Sbjct:  516 CLHPRDSGNCRGQFVRWFFDDEKKNCDVFTYTGCQGNGNNFASKEECMAICHK 568

HSP 6 Score: 52.373 bits (124), Expect = 4.796e-9
Identity = 24/54 (44.44%), Postives = 30/54 (55.56%), Query Frame = 3

Query:   60 NSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            N +C  P   G C+    RYYY+  T  C  F Y GC GN NNF S +DC++ C
Sbjct: 2137 NPLCIQPVVKGSCQEAHLRYYYDRVTDSCRLFEYSGCDGNANNFGSLEDCQRLC 2190

HSP 7 Score: 49.6766 bits (117), Expect = 4.194e-8
Identity = 20/51 (39.22%), Postives = 33/51 (64.71%), Query Frame = 3

Query:   69 CSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            CS  K++G  K Y  ++Y+N K  +CE+F++ G  GN N F++  +CE+ C
Sbjct: 1639 CSFDKDSGSGKGYNVKWYFNMKNLRCEQFVFEGLGGNTNQFETLSECERIC 1689

HSP 8 Score: 46.9802 bits (110), Expect = 4.241e-7
Identity = 18/53 (33.96%), Postives = 25/53 (47.17%), Query Frame = 3

Query:   63 SICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            + C      G C   F R+ ++     C  F YGGC GN NNF + ++C   C
Sbjct:  643 ATCEADIEVGECAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKC 695

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667211:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3e.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 68.9366 bits (167), Expect = 7.121e-15
Identity = 26/52 (50.00%), Postives = 38/52 (73.08%), Query Frame = 3

Query:   66 ICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            +C++P +AG C  Y PR+++NS+TG+CE+F YG C GN+NNF     CE+ C
Sbjct: 1650 VCAMPPDAGVCTNYTPRWFFNSQTGQCEQFAYGSCGGNENNFFDRNTCERKC 1701

HSP 2 Score: 68.1662 bits (165), Expect = 1.520e-14
Identity = 27/51 (52.94%), Postives = 36/51 (70.59%), Query Frame = 3

Query:   69 CSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            CSLPK  GPC  Y  R+Y+N+   +C+ F +GGC+GNQNNF+  +DCE  C
Sbjct:  539 CSLPKERGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCESAC 589

HSP 3 Score: 59.3066 bits (142), Expect = 1.952e-11
Identity = 26/50 (52.00%), Postives = 32/50 (64.00%), Query Frame = 3

Query:   72 SLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            SLP   GPC   F RY+YN  + KCE+F Y GC GN NN++S + CE  C
Sbjct:  427 SLP---GPCHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACEDRC 473

HSP 4 Score: 58.9214 bits (141), Expect = 3.054e-11
Identity = 24/53 (45.28%), Postives = 33/53 (62.26%), Query Frame = 3

Query:   69 CSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCHK 227
            C  P   GPCK +  R+Y+N   G C  F YGGC GN+N+F + K+CE +C +
Sbjct: 1083 CLQPVEPGPCKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECEVHCAR 1135

HSP 5 Score: 55.4546 bits (132), Expect = 4.099e-10
Identity = 21/53 (39.62%), Postives = 34/53 (64.15%), Query Frame = 3

Query:   69 CSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCHK 227
            C  P+++G C+  F R++++ +   C+ F Y GC+GN NNF S ++C   CHK
Sbjct:  737 CLHPRDSGNCRGQFVRWFFDDEKKNCDVFTYTGCQGNGNNFASKEECMAICHK 789

HSP 6 Score: 52.373 bits (124), Expect = 4.799e-9
Identity = 24/54 (44.44%), Postives = 30/54 (55.56%), Query Frame = 3

Query:   60 NSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            N +C  P   G C+    RYYY+  T  C  F Y GC GN NNF S +DC++ C
Sbjct: 2213 NPLCIQPVVKGSCQEAHLRYYYDRVTDSCRLFEYSGCDGNANNFGSLEDCQRLC 2266

HSP 7 Score: 49.6766 bits (117), Expect = 4.197e-8
Identity = 20/51 (39.22%), Postives = 33/51 (64.71%), Query Frame = 3

Query:   69 CSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            CS  K++G  K Y  ++Y+N K  +CE+F++ G  GN N F++  +CE+ C
Sbjct: 1715 CSFDKDSGSGKGYNVKWYFNMKNLRCEQFVFEGLGGNTNQFETLSECERIC 1765

HSP 8 Score: 46.9802 bits (110), Expect = 4.244e-7
Identity = 18/53 (33.96%), Postives = 25/53 (47.17%), Query Frame = 3

Query:   63 SICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            + C      G C   F R+ ++     C  F YGGC GN NNF + ++C   C
Sbjct:  864 ATCEADIEVGECAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKC 916

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Fly
Match: CG3604 (gene:FBgn0031562 transcript:FBtr0077545)

HSP 1 Score: 65.4698 bits (158), Expect = 9.978e-15
Identity = 29/51 (56.86%), Postives = 34/51 (66.67%), Query Frame = 3

Query:   69 CSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            C  PK  G C A F RY YN  T  CE+F+YGGC GN+NNF+S + CEQ C
Sbjct:   55 CHQPKETGRCFALFYRYAYNVDTQSCEEFVYGGCAGNKNNFESKEQCEQAC 105

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Fly
Match: CG3604 (gene:FBgn0031562 transcript:FBtr0346581)

HSP 1 Score: 65.4698 bits (158), Expect = 9.978e-15
Identity = 29/51 (56.86%), Postives = 34/51 (66.67%), Query Frame = 3

Query:   69 CSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            C  PK  G C A F RY YN  T  CE+F+YGGC GN+NNF+S + CEQ C
Sbjct:   55 CHQPKETGRCFALFYRYAYNVDTQSCEEFVYGGCAGNKNNFESKEQCEQAC 105

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Fly
Match: CG13748 (gene:FBgn0033355 transcript:FBtr0088656)

HSP 1 Score: 58.151 bits (139), Expect = 4.354e-12
Identity = 24/52 (46.15%), Postives = 32/52 (61.54%), Query Frame = 3

Query:   69 CSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCH 224
            C +P   G C+A  PR+ Y+ +  KC +F +GGC GN+NNF S KDC   C 
Sbjct:   60 CLMPARKGVCRALIPRWRYDPEQKKCVEFKFGGCDGNENNFASYKDCMSTCE 111

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Fly
Match: Acp24A4 (gene:FBgn0051779 transcript:FBtr0305673)

HSP 1 Score: 56.9954 bits (136), Expect = 6.505e-12
Identity = 30/75 (40.00%), Postives = 45/75 (60.00%), Query Frame = 3

Query:    3 KTILFILLCICVFENISCL-NSICSLPKNA-GPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            K ++ + + I +  N   L N IC LP  A G C A F R+ Y+++   C  FIYGGC+GN+N+F+S ++C   C
Sbjct:    2 KLLILLFVFIALASNSLALKNEICGLPAAANGNCLALFSRWSYDAQYNVCFNFIYGGCQGNENSFESQEECINKC 76

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Fly
Match: Acp24A4 (gene:FBgn0051779 transcript:FBtr0110767)

HSP 1 Score: 56.9954 bits (136), Expect = 6.505e-12
Identity = 30/75 (40.00%), Postives = 45/75 (60.00%), Query Frame = 3

Query:    3 KTILFILLCICVFENISCL-NSICSLPKNA-GPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            K ++ + + I +  N   L N IC LP  A G C A F R+ Y+++   C  FIYGGC+GN+N+F+S ++C   C
Sbjct:    2 KLLILLFVFIALASNSLALKNEICGLPAAANGNCLALFSRWSYDAQYNVCFNFIYGGCQGNENSFESQEECINKC 76

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Zebrafish
Match: wfikkn2a (info WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2a [Source:ZFIN;Acc:ZDB-GENE-120914-1])

HSP 1 Score: 68.9366 bits (167), Expect = 1.134e-14
Identity = 31/63 (49.21%), Postives = 42/63 (66.67%), Query Frame = 3

Query:   33 CVFENISCLNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            C+    + L + CSLP   GPCKAY PR+ Y+    KC+ F+YGGC GN+NNF+S + CE+ C
Sbjct:  371 CMLSCGAELAAPCSLPSVQGPCKAYKPRWAYSHALKKCQSFVYGGCGGNENNFESKEACEEMC 433

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Zebrafish
Match: tfpia (tissue factor pathway inhibitor a [Source:ZFIN;Acc:ZDB-GENE-030711-1])

HSP 1 Score: 68.1662 bits (165), Expect = 1.193e-14
Identity = 29/62 (46.77%), Postives = 42/62 (67.74%), Query Frame = 3

Query:   36 VFENISCLNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            V   +   +  C+L K+ GPCKA   R+Y++  TG+CE F YGGC+GN NNF++ +DCE+ C
Sbjct:   31 VRSELRIFHQSCALKKDEGPCKAMKDRFYFDIDTGRCEPFEYGGCQGNANNFETLQDCEEMC 92

HSP 2 Score: 61.2326 bits (147), Expect = 4.379e-12
Identity = 25/54 (46.30%), Postives = 36/54 (66.67%), Query Frame = 3

Query:   63 SICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCH 224
            S C L    GPC+   PRY+++ K+ +C++F YGGC GN NNF++ K C+Q C 
Sbjct:   99 SPCHLEDEPGPCRGLVPRYFFDQKSQECKQFFYGGCFGNANNFKTIKACQQRCQ 152

HSP 3 Score: 45.0542 bits (105), Expect = 2.993e-6
Identity = 25/76 (32.89%), Postives = 37/76 (48.68%), Query Frame = 3

Query:   63 SICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCHK*YH--------S*NSGLIFNS 266
             +C    + G C     RY +N + G+C+ F Y GC GN+NNF   + C + C K  H        + NS ++F S
Sbjct:  203 ELCMSAVDRGDCDGSERRYVFNPRIGRCQVFRYSGCGGNKNNFIHKRHCMKMCMKDQHRRKQIRIKTRNSNILFRS 278

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Zebrafish
Match: tfpia (tissue factor pathway inhibitor a [Source:ZFIN;Acc:ZDB-GENE-030711-1])

HSP 1 Score: 68.1662 bits (165), Expect = 1.207e-14
Identity = 29/62 (46.77%), Postives = 42/62 (67.74%), Query Frame = 3

Query:   36 VFENISCLNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            V   +   +  C+L K+ GPCKA   R+Y++  TG+CE F YGGC+GN NNF++ +DCE+ C
Sbjct:   30 VRSELRIFHQSCALKKDEGPCKAMKDRFYFDIDTGRCEPFEYGGCQGNANNFETLQDCEEMC 91

HSP 2 Score: 61.2326 bits (147), Expect = 4.352e-12
Identity = 25/54 (46.30%), Postives = 36/54 (66.67%), Query Frame = 3

Query:   63 SICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCH 224
            S C L    GPC+   PRY+++ K+ +C++F YGGC GN NNF++ K C+Q C 
Sbjct:   98 SPCHLEDEPGPCRGLVPRYFFDQKSQECKQFFYGGCFGNANNFKTIKACQQRCQ 151

HSP 3 Score: 45.0542 bits (105), Expect = 2.931e-6
Identity = 25/76 (32.89%), Postives = 37/76 (48.68%), Query Frame = 3

Query:   63 SICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCHK*YH--------S*NSGLIFNS 266
             +C    + G C     RY +N + G+C+ F Y GC GN+NNF   + C + C K  H        + NS ++F S
Sbjct:  202 ELCMSAVDRGDCDGSERRYVFNPRIGRCQVFRYSGCGGNKNNFIHKRHCMKMCMKDQHRRKQIRIKTRNSNILFRS 277

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Zebrafish
Match: aplp2 (amyloid beta (A4) precursor-like protein 2 [Source:ZFIN;Acc:ZDB-GENE-061009-28])

HSP 1 Score: 68.5514 bits (166), Expect = 1.912e-14
Identity = 25/57 (43.86%), Postives = 38/57 (66.67%), Query Frame = 3

Query:   57 LNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCHK 227
            + ++CSL    GPC+A  PR++++ +  KC +FIYGGC GN+NNF S + C   C +
Sbjct:  311 VEAVCSLEAETGPCRASMPRWHFDMQQRKCVRFIYGGCAGNRNNFDSEEYCMVVCKR 367

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Zebrafish
Match: aplp2 (amyloid beta (A4) precursor-like protein 2 [Source:ZFIN;Acc:ZDB-GENE-061009-28])

HSP 1 Score: 68.5514 bits (166), Expect = 2.064e-14
Identity = 25/57 (43.86%), Postives = 38/57 (66.67%), Query Frame = 3

Query:   57 LNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCHK 227
            + ++CSL    GPC+A  PR++++ +  KC +FIYGGC GN+NNF S + C   C +
Sbjct:  311 VEAVCSLEAETGPCRASMPRWHFDMQQRKCVRFIYGGCAGNRNNFDSEEYCMVVCKR 367

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Xenopus
Match: tfpi2 (tissue factor pathway inhibitor 2 [Source:NCBI gene;Acc:548483])

HSP 1 Score: 67.781 bits (164), Expect = 1.148e-14
Identity = 34/76 (44.74%), Postives = 47/76 (61.84%), Query Frame = 3

Query:    3 KTILFILLCICVFENISCLNS-ICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCHK 227
            + ++   L I VF +    N+ +C LP + GPCKA  P YYY+  T  C++F+YGGC GN N F S +DCE+ C K
Sbjct:    6 QALMAASLLIQVFGSPMQGNTTVCLLPPDEGPCKALIPHYYYDRYTQTCQEFLYGGCDGNSNKFLSMEDCEKFCWK 81

HSP 2 Score: 56.225 bits (134), Expect = 2.283e-10
Identity = 26/55 (47.27%), Postives = 34/55 (61.82%), Query Frame = 3

Query:   63 SICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCHK 227
            S C  PK+ G C A   RYY+N ++  CE+F+Y GC GN NNF   +DC+  C K
Sbjct:  147 SFCYSPKDEGSCSASVTRYYFNIESKACEEFVYTGCGGNSNNFVKMEDCDSVCKK 201

HSP 3 Score: 55.4546 bits (132), Expect = 4.633e-10
Identity = 25/58 (43.10%), Postives = 33/58 (56.90%), Query Frame = 3

Query:   48 ISCLNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            I  +   C +  + GPC+ +  RY YN +T KCE+F YGGC GN NNF+    C   C
Sbjct:   82 IKKVPKACRMDPDEGPCRGFLKRYAYNMQTMKCEQFYYGGCYGNDNNFKDKASCMDFC 139

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Xenopus
Match: APLP2 (amyloid beta (A4) precursor-like protein 2 [Source:NCBI gene;Acc:100380132])

HSP 1 Score: 68.5514 bits (166), Expect = 2.740e-14
Identity = 27/58 (46.55%), Postives = 37/58 (63.79%), Query Frame = 3

Query:   48 ISCLNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            I+ + S+CS     GPC+A  PR+Y++    KC +FIYGGC GN+NNF+S   C   C
Sbjct:  290 ITDVKSVCSQEAMTGPCRAMMPRWYFDLGQKKCVRFIYGGCGGNRNNFESEDYCMAVC 347

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Xenopus
Match: APLP2 (amyloid beta (A4) precursor-like protein 2 [Source:NCBI gene;Acc:100380132])

HSP 1 Score: 68.5514 bits (166), Expect = 2.743e-14
Identity = 27/58 (46.55%), Postives = 37/58 (63.79%), Query Frame = 3

Query:   48 ISCLNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            I+ + S+CS     GPC+A  PR+Y++    KC +FIYGGC GN+NNF+S   C   C
Sbjct:  290 ITDVKSVCSQEAMTGPCRAMMPRWYFDLGQKKCVRFIYGGCGGNRNNFESEDYCMAVC 347

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Xenopus
Match: APLP2 (amyloid beta (A4) precursor-like protein 2 [Source:NCBI gene;Acc:100380132])

HSP 1 Score: 68.5514 bits (166), Expect = 2.746e-14
Identity = 27/58 (46.55%), Postives = 37/58 (63.79%), Query Frame = 3

Query:   48 ISCLNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            I+ + S+CS     GPC+A  PR+Y++    KC +FIYGGC GN+NNF+S   C   C
Sbjct:  290 ITDVKSVCSQEAMTGPCRAMMPRWYFDLGQKKCVRFIYGGCGGNRNNFESEDYCMAVC 347

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Xenopus
Match: APLP2 (amyloid beta (A4) precursor-like protein 2 [Source:NCBI gene;Acc:100380132])

HSP 1 Score: 68.1662 bits (165), Expect = 3.112e-14
Identity = 27/58 (46.55%), Postives = 37/58 (63.79%), Query Frame = 3

Query:   48 ISCLNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            I+ + S+CS     GPC+A  PR+Y++    KC +FIYGGC GN+NNF+S   C   C
Sbjct:  293 ITDVKSVCSQEAMTGPCRAMMPRWYFDLGQKKCVRFIYGGCGGNRNNFESEDYCMAVC 350

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Mouse
Match: Wfikkn2 (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 [Source:MGI Symbol;Acc:MGI:2669209])

HSP 1 Score: 79.7221 bits (195), Expect = 2.307e-18
Identity = 35/63 (55.56%), Postives = 47/63 (74.60%), Query Frame = 3

Query:   33 CVFENISCLNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            C+   +S   +ICSLP   GPCKAY PR+ YNS+TG C+ F+YGGC+GN NNF+S + CE++C
Sbjct:  369 CMLACMSGPLAICSLPALQGPCKAYVPRWAYNSQTGLCQSFVYGGCEGNGNNFESREACEESC 431

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Mouse
Match: Spint3 (serine peptidase inhibitor, Kunitz type, 3 [Source:MGI Symbol;Acc:MGI:3651470])

HSP 1 Score: 73.1738 bits (178), Expect = 5.603e-18
Identity = 34/55 (61.82%), Postives = 40/55 (72.73%), Query Frame = 3

Query:   57 LNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            L  +C LPK+ G C+A F R+YYNSKTGKCE F YGGCKGN+NNF S   C+  C
Sbjct:   31 LPPMCILPKDIGGCRAVFVRWYYNSKTGKCEWFRYGGCKGNENNFPSRSQCQAVC 85

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Mouse
Match: Wfdc6b (WAP four-disulfide core domain 6B [Source:MGI Symbol;Acc:MGI:3575430])

HSP 1 Score: 71.633 bits (174), Expect = 7.657e-17
Identity = 31/54 (57.41%), Postives = 38/54 (70.37%), Query Frame = 3

Query:   60 NSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
              ICSLP++AGPC AY PR++YN  T  C +FIYGGC+GN NNF+S   C   C
Sbjct:   85 EDICSLPQDAGPCLAYLPRWWYNQDTKLCIEFIYGGCQGNPNNFESKAVCTSIC 138

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Mouse
Match: Wfdc6a (WAP four-disulfide core domain 6A [Source:MGI Symbol;Acc:MGI:2684968])

HSP 1 Score: 71.2478 bits (173), Expect = 9.457e-17
Identity = 30/56 (53.57%), Postives = 38/56 (67.86%), Query Frame = 3

Query:   60 NSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCHK 227
              +CSLP++ GPC AY PR++YN +T  C +FIYGGC+GN NNF S   C   C K
Sbjct:   74 QDVCSLPQDPGPCLAYLPRWWYNQETDLCTEFIYGGCQGNPNNFPSEGICTVVCKK 129

[Close]

Query:   60 NSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCHK 227
              +CSLP++ GPC AY PR++YN +T  C +FIYGGC+GN NNF S   C   C K
Sbjct:   74 QDVCSLPQDPGPCLAYLPRWWYNQETDLCTEFIYGGCQGNPNNFPSEGICTVVCKK 129

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. UniProt/SwissProt
Match: sp|P0DN09|VKT5_ANEVI (U-actitoxin-Avd3h OS=Anemonia viridis OX=51769 PE=3 SV=1)

HSP 1 Score: 83.5741 bits (205), Expect = 2.287e-21
Identity = 38/71 (53.52%), Postives = 51/71 (71.83%), Query Frame = 3

Query:   12 LFILLCICVFENIS-CLNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            +  LLC  +  ++S  +N  C LPK  GPC+A FPRYYYNS + +CEKFIYGGC+GN NNF + ++CE+ C
Sbjct:    1 MVFLLCFFLVADVSYGINGDCELPKVVGPCRARFPRYYYNSSSKRCEKFIYGGCRGNANNFHTLEECEKVC 71

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. UniProt/SwissProt
Match: sp|P0DN08|VKT53_ANEVI (KappaPI-actitoxin-Avd3e OS=Anemonia viridis OX=51769 PE=3 SV=1)

HSP 1 Score: 82.0333 bits (201), Expect = 9.567e-21
Identity = 38/71 (53.52%), Postives = 50/71 (70.42%), Query Frame = 3

Query:   12 LFILLCICVFENIS-CLNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            +  LLC  +  ++S  +N  C LPK  GPC+A FPRYYYNS + +CEKFIYGGC GN NNF + ++CE+ C
Sbjct:    1 MVFLLCFFLVADVSYGINGDCELPKVVGPCRARFPRYYYNSSSKRCEKFIYGGCGGNANNFHTLEECEKVC 71

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. UniProt/SwissProt
Match: sp|P0DN11|VKT7_ANEVI (U-actitoxin-Avd3j OS=Anemonia viridis OX=51769 PE=3 SV=1)

HSP 1 Score: 81.2629 bits (199), Expect = 2.292e-20
Identity = 37/71 (52.11%), Postives = 50/71 (70.42%), Query Frame = 3

Query:   12 LFILLCICVFENIS-CLNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            +  LLC  +  ++S  +N  C LPK  GPC+A  PRYYYNS + +CEKFIYGGC+GN NNF + ++CE+ C
Sbjct:    1 MVFLLCFFLVADVSYGINGDCELPKVVGPCRASHPRYYYNSSSKRCEKFIYGGCRGNANNFHTLEECEKVC 71

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. UniProt/SwissProt
Match: sp|P0DMW6|VKT3A_ACTEQ (PI-actitoxin-Aeq3a OS=Actinia equina OX=6106 PE=1 SV=1)

HSP 1 Score: 80.1073 bits (196), Expect = 2.562e-20
Identity = 33/55 (60.00%), Postives = 42/55 (76.36%), Query Frame = 3

Query:   60 NSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCH 224
            NS C LP   G C+ YFPRYYYN++ GKC++FIYGGC GN+NNF++ +DC   CH
Sbjct:    3 NSFCQLPAVVGKCRGYFPRYYYNTEAGKCQQFIYGGCGGNRNNFETVEDCRATCH 57

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. UniProt/SwissProt
Match: sp|P0DN10|VKT6_ANEVI (U-actitoxin-Avd3i OS=Anemonia viridis OX=51769 PE=3 SV=1)

HSP 1 Score: 79.7221 bits (195), Expect = 7.699e-20
Identity = 37/71 (52.11%), Postives = 50/71 (70.42%), Query Frame = 3

Query:   12 LFILLCICVFENIS-CLNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            +  LLC  +  ++S  +N  C LPK  GPC+A F RYYYNS + +CEKFIYGGC+GN NNF + ++CE+ C
Sbjct:    1 MVFLLCFFLVADVSYGINGDCELPKVVGPCRAGFRRYYYNSSSKRCEKFIYGGCRGNANNFHTLEECEKVC 71

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. TrEMBL
Match: I1ZII0 (Serine protease inhibitor-1 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 152.14 bits (383), Expect = 5.207e-46
Identity = 75/75 (100.00%), Postives = 75/75 (100.00%), Query Frame = 3

Query:    3 KTILFILLCICVFENISCLNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCHK 227
            KTILFILLCICVFENISCLNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCHK
Sbjct:    1 KTILFILLCICVFENISCLNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCHK 75

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. TrEMBL
Match: A0A2P6KJL5 (Kunitz-type serine protease inhibitor taicotoxin OS=Nephila clavipes OX=2585209 GN=NCL1_37845 PE=4 SV=1)

HSP 1 Score: 83.5741 bits (205), Expect = 5.952e-19
Identity = 34/69 (49.28%), Postives = 49/69 (71.01%), Query Frame = 3

Query:   21 LLCICVFENISCLNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCHK 227
            L+ + +       N  CSLP N GPC+A  PR+YY+S + KCEKF+YGGC+GN+NNF++ +DC++ C K
Sbjct:   12 LISVIISTATGADNDFCSLPPNTGPCRAAMPRFYYDSHSNKCEKFLYGGCQGNKNNFKTIEDCQETCAK 80

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. TrEMBL
Match: A0A2P6JVV9 (U-actitoxin-Avd3j OS=Nephila clavipes OX=2585209 GN=NCL1_61548 PE=4 SV=1)

HSP 1 Score: 82.4185 bits (202), Expect = 3.233e-18
Identity = 36/56 (64.29%), Postives = 42/56 (75.00%), Query Frame = 3

Query:   60 NSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCHK 227
            +SIC L K  GPCKA  PR+YYN  T KCE+FIYGGCKGN NNFQ+ +DCE  C +
Sbjct:   31 DSICELKKEVGPCKAAMPRFYYNKNTKKCERFIYGGCKGNNNNFQTLEDCEVTCER 86

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. TrEMBL
Match: A0A151HYY2 (Taicatoxin, serine protease inhibitor component OS=Atta colombica OX=520822 GN=ALC53_12607 PE=4 SV=1)

HSP 1 Score: 79.7221 bits (195), Expect = 2.496e-17
Identity = 34/74 (45.95%), Postives = 48/74 (64.86%), Query Frame = 3

Query:    9 ILFILLCICVFENISCLN---SICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            +LF+ + + +   I+      S+C LP N GPC+A  PRY YNS +G+CE+FIYGGC  N NNF++  +CE  C
Sbjct:   11 LLFVFIIVILMHEITSKQLYPSLCLLPMNTGPCRAQIPRYAYNSASGQCEQFIYGGCHANANNFKTISECEMTC 84

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. TrEMBL
Match: A0A4Y2AA33 (BPTI/Kunitz inhibitor domain-containing protein OS=Araneus ventricosus OX=182803 GN=AVEN_106515_1 PE=4 SV=1)

HSP 1 Score: 80.1073 bits (196), Expect = 2.607e-17
Identity = 32/54 (59.26%), Postives = 44/54 (81.48%), Query Frame = 3

Query:   60 NSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            NS+C  PK++GPC A FPR++YN +TG+CE+F YGGC GN+NNF++  DCE+ C
Sbjct:   17 NSVCMEPKDSGPCMALFPRWFYNQQTGQCEEFTYGGCSGNKNNFKTKNDCEKAC 70

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Cavefish
Match: wfikkn2b (WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 [Source:NCBI gene;Acc:103024700])

HSP 1 Score: 70.8626 bits (172), Expect = 2.167e-15
Identity = 29/51 (56.86%), Postives = 39/51 (76.47%), Query Frame = 3

Query:   69 CSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            CSLP   GPCKAY PR+ Y+   G+C+ FIYGGC+GN+NNF++ + CE +C
Sbjct:  374 CSLPSLQGPCKAYEPRWAYSITLGQCQPFIYGGCEGNENNFETRETCEDSC 424

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Cavefish
Match: lrp11 (LDL receptor related protein 11 [Source:NCBI gene;Acc:103032685])

HSP 1 Score: 70.8626 bits (172), Expect = 2.175e-15
Identity = 26/51 (50.98%), Postives = 34/51 (66.67%), Query Frame = 3

Query:   69 CSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            C  P   GPC+  FPR+YY++  G+C+ F+YGGCKGN+NNF    DC   C
Sbjct:  417 CMEPPVVGPCRGTFPRWYYDAAAGECKHFLYGGCKGNRNNFLQQTDCVNEC 467

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Cavefish
Match: lrp11 (LDL receptor related protein 11 [Source:NCBI gene;Acc:103032685])

HSP 1 Score: 69.707 bits (169), Expect = 5.777e-15
Identity = 26/51 (50.98%), Postives = 34/51 (66.67%), Query Frame = 3

Query:   69 CSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            C  P   GPC+  FPR+YY++  G+C+ F+YGGCKGN+NNF    DC   C
Sbjct:  417 CMEPPVVGPCRGTFPRWYYDAAAGECKHFLYGGCKGNRNNFLQQTDCVNEC 467

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Cavefish
Match: col28a2a (collagen alpha-1(XXVIII) chain-like [Source:NCBI gene;Acc:103029985])

HSP 1 Score: 69.3218 bits (168), Expect = 9.564e-15
Identity = 24/55 (43.64%), Postives = 36/55 (65.45%), Query Frame = 3

Query:   57 LNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            L+  CSL  N GPC+ Y  R+YY+     C +F YGGC+GN+N F++  +C++ C
Sbjct: 1190 LDPRCSLSLNQGPCREYLIRWYYDKAANSCAQFWYGGCEGNENRFETEAECKKTC 1244

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Cavefish
Match: aplp2 (amyloid beta precursor like protein 2 [Source:NCBI gene;Acc:103022515])

HSP 1 Score: 68.9366 bits (167), Expect = 1.108e-14
Identity = 25/57 (43.86%), Postives = 38/57 (66.67%), Query Frame = 3

Query:   57 LNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCHK 227
            + ++CSL    GPC+A  PR++++ +  KC +FIYGGC GN+NNF S + C   C +
Sbjct:  311 VKAVCSLEAETGPCRASMPRWHFDMQQRKCVRFIYGGCAGNRNNFDSEEYCMAVCKR 367

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Sea Lamprey
Match: WFIKKN1 (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30912])

HSP 1 Score: 70.4774 bits (171), Expect = 7.079e-16
Identity = 33/69 (47.83%), Postives = 44/69 (63.77%), Query Frame = 3

Query:   15 FILLCICVFENISCLNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            FI    C    ++ +N+ CSLP   GPCK +  R+ YN    +C+ FIYGGC+GN+NNFQS + CE NC
Sbjct:  356 FITYEECKMACMANINNTCSLPVQQGPCKQWALRWAYNPLIKRCQSFIYGGCEGNENNFQSQELCEDNC 424

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Sea Lamprey
Match: tfpi2 (tissue factor pathway inhibitor 2 [Source:ZFIN;Acc:ZDB-GENE-060503-38])

HSP 1 Score: 66.2402 bits (160), Expect = 8.293e-15
Identity = 29/70 (41.43%), Postives = 43/70 (61.43%), Query Frame = 3

Query:   12 LFILLCICVFENISCLNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            +++    CVF  +      C+LP   G C+A FPRY++N  T +CE FIYGGC  N+NNF++ ++C   C
Sbjct:    9 MYLSESQCVF-TLEDQRVTCTLPAKPGDCRAAFPRYFFNRSTLRCESFIYGGCHSNENNFETMQECRAAC 77

HSP 2 Score: 50.0618 bits (118), Expect = 6.278e-9
Identity = 21/52 (40.38%), Postives = 29/52 (55.77%), Query Frame = 3

Query:   66 ICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            +C      G C+A+  RY+YN   G C  F+YGGC GN N F+  + C  +C
Sbjct:   86 LCRPDAETGRCRAHITRYFYNMTLGMCMPFVYGGCGGNNNRFEDMESCVFSC 137

HSP 3 Score: 44.669 bits (104), Expect = 6.088e-7
Identity = 27/65 (41.54%), Postives = 33/65 (50.77%), Query Frame = 3

Query:   33 CVFENISCLNSI--CSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            CVF  I   N+   C    + G C+  F R+YYN +   C  F Y GC GN NNF S+K C   C
Sbjct:  133 CVFSCIEKPNTPRECLSRHDTGNCQGNFRRFYYNIQKRSCLPFSYSGCGGNNNNFISAKTCLSTC 197

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008261.1 (pep scaffold:Pmarinus_7.0:GL478901:735:1448:1 gene:ENSPMAG00000007479.1 transcript:ENSPMAT00000008261.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 61.6178 bits (148), Expect = 2.770e-13
Identity = 28/60 (46.67%), Postives = 38/60 (63.33%), Query Frame = 3

Query:   51 SCLNS---ICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            +C+N    +CSLP   GPCKA+  R+ YN    +C  F+YGGC+GN N+F S   CE+ C
Sbjct:   12 ACVNETARVCSLPPVQGPCKAWETRWSYNPLGKRCATFLYGGCEGNGNSFASRSACERAC 71

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005038.1 (pep scaffold:Pmarinus_7.0:GL481015:31246:35903:1 gene:ENSPMAG00000004579.1 transcript:ENSPMAT00000005038.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 60.077 bits (144), Expect = 1.498e-12
Identity = 27/53 (50.94%), Postives = 34/53 (64.15%), Query Frame = 3

Query:   63 SICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            S C +  + GPC+AY PR +YN  T +CE F YGGC GN NNF+S  +C   C
Sbjct:    1 SSCMMDLDPGPCRAYLPRVFYNRYTQRCEPFHYGGCFGNGNNFESLAECNAKC 53

HSP 2 Score: 59.3066 bits (142), Expect = 2.357e-12
Identity = 27/55 (49.09%), Postives = 32/55 (58.18%), Query Frame = 3

Query:   57 LNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            L  IC +  + G C A  PR++YN KT  CE F YGGC GN NNF S + C   C
Sbjct:  163 LPRICLMKADPGECTAVIPRFHYNPKTSNCESFTYGGCGGNDNNFSSERSCMSVC 217

HSP 3 Score: 55.4546 bits (132), Expect = 7.237e-11
Identity = 24/51 (47.06%), Postives = 33/51 (64.71%), Query Frame = 3

Query:   69 CSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            C L    G C+A   RY++N  +G CE+F YGGC+GN NNF+ +  C Q+C
Sbjct:   75 CRLDMEVGVCRALLRRYFFNMTSGSCEEFGYGGCQGNLNNFKDAASCYQHC 125

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005043.1 (pep scaffold:Pmarinus_7.0:GL481015:31246:35903:1 gene:ENSPMAG00000004579.1 transcript:ENSPMAT00000005043.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 59.6918 bits (143), Expect = 1.627e-12
Identity = 27/53 (50.94%), Postives = 34/53 (64.15%), Query Frame = 3

Query:   63 SICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            S C +  + GPC+AY PR +YN  T +CE F YGGC GN NNF+S  +C   C
Sbjct:    1 SSCMMDLDPGPCRAYLPRVFYNRYTQRCEPFHYGGCFGNGNNFESLAECNAKC 53

HSP 2 Score: 59.3066 bits (142), Expect = 2.456e-12
Identity = 27/55 (49.09%), Postives = 32/55 (58.18%), Query Frame = 3

Query:   57 LNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            L  IC +  + G C A  PR++YN KT  CE F YGGC GN NNF S + C   C
Sbjct:  162 LPRICLMKADPGECTAVIPRFHYNPKTSNCESFTYGGCGGNDNNFSSERSCMSVC 216

HSP 3 Score: 55.0694 bits (131), Expect = 9.167e-11
Identity = 24/51 (47.06%), Postives = 33/51 (64.71%), Query Frame = 3

Query:   69 CSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            C L    G C+A   RY++N  +G CE+F YGGC+GN NNF+ +  C Q+C
Sbjct:   74 CRLDMEVGVCRALLRRYFFNMTSGSCEEFGYGGCQGNLNNFKDAASCYQHC 124

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Nematostella
Match: EDO47795 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RL41])

HSP 1 Score: 75.8702 bits (185), Expect = 5.934e-20
Identity = 31/52 (59.62%), Postives = 41/52 (78.85%), Query Frame = 3

Query:   66 ICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            IC LPK  GPC AY PR+YYN+K  +C+KF+YGGC+GN N F+S + CE++C
Sbjct:    1 ICQLPKLPGPCSAYVPRWYYNAKHRRCQKFVYGGCRGNANRFKSHRSCERSC 52

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Nematostella
Match: EDO29819 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T2J6])

HSP 1 Score: 73.1738 bits (178), Expect = 7.804e-19
Identity = 30/54 (55.56%), Postives = 41/54 (75.93%), Query Frame = 3

Query:   60 NSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            NS C+LPK  G C+A  PR ++NS++GKCE FIYGGC GN NNF + ++C++ C
Sbjct:   11 NSACTLPKKVGDCRAAMPRVFFNSQSGKCEDFIYGGCGGNANNFHTMEECKKAC 64

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Nematostella
Match: EDO38284 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SDB9])

HSP 1 Score: 70.0922 bits (170), Expect = 1.513e-17
Identity = 30/55 (54.55%), Postives = 39/55 (70.91%), Query Frame = 3

Query:   57 LNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            + S+C LPK AGPC A   R+YYN+K GKC+ F++GGC  N NNF++ K CE  C
Sbjct:    9 IKSVCKLPKFAGPCMASIERFYYNAKIGKCQSFVFGGCLPNGNNFKTRKACEAKC 63

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Nematostella
Match: EDO41696 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3T1])

HSP 1 Score: 67.781 bits (164), Expect = 7.542e-17
Identity = 28/51 (54.90%), Postives = 39/51 (76.47%), Query Frame = 3

Query:   69 CSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            C  PK  GPC+AYF R++YN  + KC++F+YGGC+GN NNF+S  +CE+ C
Sbjct:    2 CLQPKLTGPCRAYFERWFYNQTSRKCKQFVYGGCQGNSNNFESKAECEKKC 52

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Nematostella
Match: EDO26263 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3T1])

HSP 1 Score: 67.781 bits (164), Expect = 7.542e-17
Identity = 28/51 (54.90%), Postives = 39/51 (76.47%), Query Frame = 3

Query:   69 CSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            C  PK  GPC+AYF R++YN  + KC++F+YGGC+GN NNF+S  +CE+ C
Sbjct:    2 CLQPKLTGPCRAYFERWFYNQTSRKCKQFVYGGCQGNSNNFESKAECEKKC 52

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Medaka
Match: wfikkn2a (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 [Source:NCBI gene;Acc:101168544])

HSP 1 Score: 72.7886 bits (177), Expect = 4.785e-16
Identity = 32/55 (58.18%), Postives = 40/55 (72.73%), Query Frame = 3

Query:   57 LNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            L + CSLP   GPCKAY PR+ Y+S   KC+ F+YGGC GN+NNF+S + CEQ C
Sbjct:  384 LAAPCSLPSLQGPCKAYEPRWAYSSTLKKCQSFVYGGCGGNENNFESKEACEQMC 438

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Medaka
Match: lrp11 (low-density lipoprotein receptor-related protein 11 [Source:NCBI gene;Acc:101175213])

HSP 1 Score: 68.5514 bits (166), Expect = 1.416e-14
Identity = 27/62 (43.55%), Postives = 36/62 (58.06%), Query Frame = 3

Query:   36 VFENISCLNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            +F+  +     C      GPCK  FPR+YY+  TG+C+ F+YGGC+GN NNF    DC   C
Sbjct:  383 IFKETAVGQDPCGADPVVGPCKGTFPRWYYDQNTGECKHFLYGGCQGNHNNFLQELDCISEC 444

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Medaka
Match: ENSORLT00000012975.2 (pep primary_assembly:ASM223467v1:12:15740273:15760140:1 gene:ENSORLG00000010354.2 transcript:ENSORLT00000012975.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 65.0846 bits (157), Expect = 4.209e-14
Identity = 28/52 (53.85%), Postives = 37/52 (71.15%), Query Frame = 3

Query:   66 ICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            +C+   ++G C  YF RY+YN + G+CE FIYGGC GNQNNF + K+C Q C
Sbjct:  124 VCAQAPDSGLCFGYFERYFYNFRKGRCEIFIYGGCLGNQNNFLTEKECLQRC 175

HSP 2 Score: 63.1586 bits (152), Expect = 1.935e-13
Identity = 28/56 (50.00%), Postives = 37/56 (66.07%), Query Frame = 3

Query:   51 SCLNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQN 218
            S    +C+   ++G C  YF RY+YN + G+CE FIYGGC GNQNNF + K+C Q 
Sbjct:   67 SASTGVCAQAPDSGLCFGYFERYFYNFRKGRCEIFIYGGCLGNQNNFLTEKECLQR 122

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Medaka
Match: aplp2 (amyloid beta precursor like protein 2 [Source:NCBI gene;Acc:101168561])

HSP 1 Score: 67.3958 bits (163), Expect = 4.337e-14
Identity = 24/57 (42.11%), Postives = 37/57 (64.91%), Query Frame = 3

Query:   57 LNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCHK 227
            + ++C+L    GPC+A  PR++++    KC +FIYGGC GN+NNF S + C   C +
Sbjct:  310 VKAVCTLEAETGPCRASMPRWHFDLSQRKCVRFIYGGCAGNRNNFDSEEYCMAVCKR 366

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Medaka
Match: aplp2 (amyloid beta precursor like protein 2 [Source:NCBI gene;Acc:101168561])

HSP 1 Score: 67.3958 bits (163), Expect = 4.342e-14
Identity = 24/57 (42.11%), Postives = 37/57 (64.91%), Query Frame = 3

Query:   57 LNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCHK 227
            + ++C+L    GPC+A  PR++++    KC +FIYGGC GN+NNF S + C   C +
Sbjct:  310 VKAVCTLEAETGPCRASMPRWHFDLSQRKCVRFIYGGCAGNRNNFDSEEYCMAVCKR 366

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Planmine SMEST
Match: SMESG000013910.1 (SMESG000013910.1)

HSP 1 Score: 77.0258 bits (188), Expect = 5.098e-20
Identity = 33/59 (55.93%), Postives = 42/59 (71.19%), Query Frame = 3

Query:   51 SCLNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCHK 227
             C    CSLPK  G C+ YFPRY++N +TGKCEKFIYGGC+GN+NNF +  +C   C +
Sbjct:   14 DCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 72

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Planmine SMEST
Match: SMESG000013909.1 (SMESG000013909.1)

HSP 1 Score: 75.0998 bits (183), Expect = 3.480e-19
Identity = 32/73 (43.84%), Postives = 48/73 (65.75%), Query Frame = 3

Query:    9 ILFILLCICVFENISCLNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCHK 227
            I F +  I   + I C    C L  + GPC+A FP +++N++TGKCE+F+YGGC GN N F + ++C++NC K
Sbjct:    5 ITFSIFVIFAIQFIECRKPECLLEMDQGPCRAAFPMFFFNTETGKCEEFVYGGCLGNDNLFGTYEECQENCEK 77

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Planmine SMEST
Match: SMESG000013915.1 (SMESG000013915.1)

HSP 1 Score: 75.485 bits (184), Expect = 5.219e-19
Identity = 32/53 (60.38%), Postives = 41/53 (77.36%), Query Frame = 3

Query:   69 CSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCHK 227
            CSLPK  G C+ YFPRY++N +TGKCEKFIYGGC+GN+NNF +  +C   C +
Sbjct:   45 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 97

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Planmine SMEST
Match: SMESG000038004.1 (SMESG000038004.1)

HSP 1 Score: 73.9442 bits (180), Expect = 1.059e-18
Identity = 38/73 (52.05%), Postives = 46/73 (63.01%), Query Frame = 3

Query:    9 ILFILLCICVFENISCLNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCHK 227
            I FI L   +F  I CL   C  PK +GPC  Y  RYYYN+ T KCEKFIYGGCK N NNF++ + C+  C +
Sbjct:    5 IKFIPLSCLMFFAIQCLEHNCDDPKTSGPCYGYILRYYYNNNTTKCEKFIYGGCKPNGNNFKTLEACQDFCEE 77

[Close]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Planmine SMEST
Match: SMESG000037999.1 (SMESG000037999.1)

HSP 1 Score: 73.9442 bits (180), Expect = 1.143e-18
Identity = 36/71 (50.70%), Postives = 48/71 (67.61%), Query Frame = 3

Query:   18 ILLCICVFENISCLNSI---CSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNC 221
            IL+ + +F     L S    C+ PK +G C+AYF R+Y+NS+TGKCE FIYGGC  N NNFQ+  +CE+ C
Sbjct:    5 ILVLVVLFSLSQLLESRLKECNEPKQSGMCEAYFKRFYFNSETGKCETFIYGGCGKNGNNFQTEDECEELC 75

The following BLAST results are available for this feature:

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Human
BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Celegans
BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Fly
BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Zebrafish
BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Xenopus
BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Mouse
BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. UniProt/SwissProt
BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. TrEMBL
BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Cavefish
BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Sea Lamprey
BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Yeast
BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Nematostella
BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Medaka
BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Planmine SMEST

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
WFIKKN2	2.933e-18	53.97	WAP, follistatin/kazal, immunoglobulin, kunitz and...	[more]
WFIKKN2	6.908e-18	53.97	WAP, follistatin/kazal, immunoglobulin, kunitz and...	[more]
TFPI	6.178e-15	43.33	tissue factor pathway inhibitor [Source:HGNC Symbo...	[more]
TFPI	6.178e-15	43.33	tissue factor pathway inhibitor [Source:HGNC Symbo...	[more]
TFPI	6.792e-15	44.83	tissue factor pathway inhibitor [Source:HGNC Symbo...	[more]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mlt-11	2.140e-15	50.00	pep chromosome:WBcel235:V:20667211:20678513:1 gene...	[more]
mlt-11	2.161e-15	50.00	pep chromosome:WBcel235:V:20667211:20678513:1 gene...	[more]
mlt-11	2.474e-15	50.00	pep chromosome:WBcel235:V:20667209:20678513:1 gene...	[more]
mlt-11	7.116e-15	50.00	pep chromosome:WBcel235:V:20667209:20678513:1 gene...	[more]
mlt-11	7.121e-15	50.00	pep chromosome:WBcel235:V:20667211:20678513:1 gene...	[more]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CG3604	9.978e-15	56.86	gene:FBgn0031562 transcript:FBtr0077545	[more]
CG3604	9.978e-15	56.86	gene:FBgn0031562 transcript:FBtr0346581	[more]
CG13748	4.354e-12	46.15	gene:FBgn0033355 transcript:FBtr0088656	[more]
Acp24A4	6.505e-12	40.00	gene:FBgn0051779 transcript:FBtr0305673	[more]
Acp24A4	6.505e-12	40.00	gene:FBgn0051779 transcript:FBtr0110767	[more]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
wfikkn2a	1.134e-14	49.21	info WAP, follistatin/kazal, immunoglobulin, kunit...	[more]
tfpia	1.193e-14	46.77	tissue factor pathway inhibitor a [Source:ZFIN;Acc...	[more]
tfpia	1.207e-14	46.77	tissue factor pathway inhibitor a [Source:ZFIN;Acc...	[more]
aplp2	1.912e-14	43.86	amyloid beta (A4) precursor-like protein 2 [Source...	[more]
aplp2	2.064e-14	43.86	amyloid beta (A4) precursor-like protein 2 [Source...	[more]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tfpi2	1.148e-14	44.74	tissue factor pathway inhibitor 2 [Source:NCBI gen...	[more]
APLP2	2.740e-14	46.55	amyloid beta (A4) precursor-like protein 2 [Source...	[more]
APLP2	2.743e-14	46.55	amyloid beta (A4) precursor-like protein 2 [Source...	[more]
APLP2	2.746e-14	46.55	amyloid beta (A4) precursor-like protein 2 [Source...	[more]
APLP2	3.112e-14	46.55	amyloid beta (A4) precursor-like protein 2 [Source...	[more]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Wfikkn2	2.307e-18	55.56	WAP, follistatin/kazal, immunoglobulin, kunitz and...	[more]
Spint3	5.603e-18	61.82	serine peptidase inhibitor, Kunitz type, 3 [Source...	[more]
Wfdc6b	7.657e-17	57.41	WAP four-disulfide core domain 6B [Source:MGI Symb...	[more]
Wfdc6a	9.457e-17	53.57	WAP four-disulfide core domain 6A [Source:MGI Symb...	[more]
Wfdc6a	9.457e-17	53.57	WAP four-disulfide core domain 6A [Source:MGI Symb...	[more]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P0DN09\|VKT5_ANEVI	2.287e-21	53.52	U-actitoxin-Avd3h OS=Anemonia viridis OX=51769 PE=...	[more]
sp\|P0DN08\|VKT53_ANEVI	9.567e-21	53.52	KappaPI-actitoxin-Avd3e OS=Anemonia viridis OX=517...	[more]
sp\|P0DN11\|VKT7_ANEVI	2.292e-20	52.11	U-actitoxin-Avd3j OS=Anemonia viridis OX=51769 PE=...	[more]
sp\|P0DMW6\|VKT3A_ACTEQ	2.562e-20	60.00	PI-actitoxin-Aeq3a OS=Actinia equina OX=6106 PE=1 ...	[more]
sp\|P0DN10\|VKT6_ANEVI	7.699e-20	52.11	U-actitoxin-Avd3i OS=Anemonia viridis OX=51769 PE=...	[more]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
I1ZII0	5.207e-46	100.00	Serine protease inhibitor-1 (Fragment) OS=Schmidte...	[more]
A0A2P6KJL5	5.952e-19	49.28	Kunitz-type serine protease inhibitor taicotoxin O...	[more]
A0A2P6JVV9	3.233e-18	64.29	U-actitoxin-Avd3j OS=Nephila clavipes OX=2585209 G...	[more]
A0A151HYY2	2.496e-17	45.95	Taicatoxin, serine protease inhibitor component OS...	[more]
A0A4Y2AA33	2.607e-17	59.26	BPTI/Kunitz inhibitor domain-containing protein OS...	[more]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
wfikkn2b	2.167e-15	56.86	WAP, Kazal, immunoglobulin, Kunitz and NTR domain-...	[more]
lrp11	2.175e-15	50.98	LDL receptor related protein 11 [Source:NCBI gene;...	[more]
lrp11	5.777e-15	50.98	LDL receptor related protein 11 [Source:NCBI gene;...	[more]
col28a2a	9.564e-15	43.64	collagen alpha-1(XXVIII) chain-like [Source:NCBI g...	[more]
aplp2	1.108e-14	43.86	amyloid beta precursor like protein 2 [Source:NCBI...	[more]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
WFIKKN1	7.079e-16	47.83	WAP, follistatin/kazal, immunoglobulin, kunitz and...	[more]
tfpi2	8.293e-15	41.43	tissue factor pathway inhibitor 2 [Source:ZFIN;Acc...	[more]
ENSPMAT00000008261.1	2.770e-13	46.67	pep scaffold:Pmarinus_7.0:GL478901:735:1448:1 gene...	[more]
ENSPMAT00000005038.1	1.498e-12	50.94	pep scaffold:Pmarinus_7.0:GL481015:31246:35903:1 g...	[more]
ENSPMAT00000005043.1	1.627e-12	50.94	pep scaffold:Pmarinus_7.0:GL481015:31246:35903:1 g...	[more]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO47795	5.934e-20	59.62	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO29819	7.804e-19	55.56	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO38284	1.513e-17	54.55	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO41696	7.542e-17	54.90	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO26263	7.542e-17	54.90	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
wfikkn2a	4.785e-16	58.18	WAP, follistatin/kazal, immunoglobulin, kunitz and...	[more]
lrp11	1.416e-14	43.55	low-density lipoprotein receptor-related protein 1...	[more]
ENSORLT00000012975.2	4.209e-14	53.85	pep primary_assembly:ASM223467v1:12:15740273:15760...	[more]
aplp2	4.337e-14	42.11	amyloid beta precursor like protein 2 [Source:NCBI...	[more]
aplp2	4.342e-14	42.11	amyloid beta precursor like protein 2 [Source:NCBI...	[more]

BLAST of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000013910.1	5.098e-20	55.93	SMESG000013910.1	[more]
SMESG000013909.1	3.480e-19	43.84	SMESG000013909.1	[more]
SMESG000013915.1	5.219e-19	60.38	SMESG000013915.1	[more]
SMESG000038004.1	1.059e-18	52.05	SMESG000038004.1	[more]
SMESG000037999.1	1.143e-18	50.70	SMESG000037999.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence

transcript sequence

>SMED30020397 ID=SMED30020397|Name=WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2|organism=Schmidtea mediterranea sexual|type=transcript|length=323bp
TGAAAACAATTCTTTTCATTTTGCTTTGCATTTGTGTTTTTGAAAACATA
AGTTGTCTTAATAGTATATGCTCCCTTCCAAAGAATGCGGGCCCTTGCAA
AGCTTATTTTCCAAGATATTATTATAATTCAAAGACTGGAAAATGCGAAA
AATTCATTTATGGAGGCTGCAAAGGAAATCAAAATAATTTTCAAAGTAGC
AAGGATTGTGAACAAAATTGTCATAAATAATATCACTCATAAAATTCTGG
ATTAATCTTTAATAGCTGCCATTTTAATAATAAATATAATAAACATTCTG
AAAAAAAAAAAAAAAAAATGCGA

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **cellular component**
Term	Definition
GO:0005576	extracellular region

Vocabulary: **biological process**
Term	Definition
GO:0010466	negative regulation of peptidase activity
GO:0006508	proteolysis
GO:0010951	negative regulation of endopeptidase activity

Vocabulary: **molecular function**
Term	Definition
GO:0030414	peptidase inhibitor activity
GO:0004867	serine-type endopeptidase inhibitor activity
GO:0008233	peptidase activity

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000136	whole organism
PLANA:0000421	tail
PLANA:0002032	epidermal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036880	Kunitz_BPTI_sf
IPR002223	Kunitz_BPTI
IPR020901	Prtase_inh_Kunz-CS

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR002223	Pancreatic trypsin inhibitor Kunitz domain	PRINTS	PR00759	BASICPTASE	coord: 20..34 score: 38.35 coord: 48..58 score: 63.89 coord: 58..73 score: 46.23
IPR002223	Pancreatic trypsin inhibitor Kunitz domain	SMART	SM00131	KU_2	coord: 21..74 e-value: 3.7E-25 score: 99.6
IPR002223	Pancreatic trypsin inhibitor Kunitz domain	PFAM	PF00014	Kunitz_BPTI	coord: 22..73 e-value: 9.7E-22 score: 77.0
IPR002223	Pancreatic trypsin inhibitor Kunitz domain	PROSITE	PS50279	BPTI_KUNITZ_2	coord: 23..73 score: 16.204
IPR002223	Pancreatic trypsin inhibitor Kunitz domain	CDD	cd00109	KU	coord: 21..73 e-value: 1.50578E-21 score: 76.905
IPR036880	Pancreatic trypsin inhibitor Kunitz domain superfamily	GENE3D	G3DSA:4.10.410.10		coord: 20..75 e-value: 1.7E-25 score: 90.6
IPR036880	Pancreatic trypsin inhibitor Kunitz domain superfamily	SUPERFAMILY	SSF57362	BPTI-like	coord: 15..74
None	No IPR available	PANTHER	PTHR10083:SF328	TISSUE FACTOR PATHWAY INHIBITOR	coord: 21..74
None	No IPR available	PANTHER	PTHR10083	KUNITZ-TYPE PROTEASE INHIBITOR-RELATED	coord: 21..74
None	No IPR available	SIGNALP_EUK	SignalP-noTM	SignalP-noTM	coord: 1..18 score: 0.799
IPR020901	Proteinase inhibitor I2, Kunitz, conserved site	PROSITE	PS00280	BPTI_KUNITZ_1	coord: 51..69

Main menu

WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2

Zeng et. al., 2018

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 8

Owlery

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