Transient receptor potential cation channel

Query:  196 SLSTVSEKYNWIDDNILKLECNRFHP--KSNGYCACGRPAEEHIN-----------KNQFHNS-SKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQI-----LTLRQVGSLIEILMGGGYQHQYCQK---------LSPGK-SLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVD----NSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXX-XXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEYLN 2439
            S+  +  + +WI+    K EC    P  K    C CGR   +H+            KN+   S + I++E W+I  +T   PTDA+GT+EFQGG H  KA YVR+S+ T P  +LHL+ +EW L +P L+IS+ GGL NF+LQPKLK+VF  GL+KAA TTG W+ T G++TGV +HVG+ALK+        I  +GI+PWGIV++++ L+G++ + PY +++N   K  VLN  H++F+LADNGT  K+GAE+ LRR LE++++ Q I    + R+G+  VPVVA++VEGG     +V E + D  PVPVVVC+GSGRA+D+LAF H+YS+E G +   +R+Q+L T+Q+TF+    +A+ L+  +  C+K++ELITV+RM  +G  DID+AILTALL+ +    +  DQL+L +AWNR DIARSQIF    +W    L+ AM+DAL+ DR+DFVKLL+ENGV+MHRFL +SRLE  YN R        N++   V ++KK  +     ++L  +G +IE LMGG Y+  Y +K           P +   L +  M D +      K   +    E E+ +D      ++F +P+ EL+ W +L +R  MA++    GEE++AK+L+A         +  + D   +  +EL      F  L+V L D  YK + +   +LL YEL+ +S  T + LA   + + F+ H C+Q +L D+W G LR  K  GLKV++ +L        LP ++L+L      EFK K ++    Q  E +L 
Sbjct:   54 SVRLLKAQKSWIERAFYKRECVHIIPSTKDPHRCCCGRLIGQHVGLTPSISVLQNEKNESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKI----NTRIGQG-VPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGA--NASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTR----HGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPLRRGRK---TTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGIL--------LPPSILSL------EFKNKDDMPYMSQAQEIHLQ 808          

Query: 3202 KKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYV-HIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPVDFPEESR-------LTPL---AWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGN--VIKRTLQCMDQTQFQIGELHSRFNVMRV 4461
            +KIYEF+ API KF+   +++I  ++L   +  +K  +ER    + +I + +I T  ++  R+   +    + QK+KV  +  WN  D       ++ FSV      Q Q  +                     GR +  +   YW I+ L++    +  G Y+ MI  M+  ++  V+I+ V++ +FGV RQ I++    +     + KNI+  PY+M+YGEV+A +IDP     E+R       L P    AW VP  M  ++L A +++++L+IA   + + ++K  S +V+ + RY +I+ +  RP  PPP II   +      M F    C     R   H + P       D R++  GLKLF++ DE++K+HDFEE+C+E+Y++     D F   N   I+ T + ++    ++ E++ R + M+ 
Sbjct:  860 RKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVK--MERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDL----IAILLFSVGMILRLQDQPFRSD-------------------GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPN--EEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHM-----TMIFQHLCC-----RWRKHESDP-------DERDY--GLKLFITDDELKKVHDFEEQCIEEYFREKD--DRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKA 1244          

Query:  196 SLSTVSEKYNWIDDNILKLECNRFHP--KSNGYCACGRPAEEHIN-----------KNQFHNS-SKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQI-----LTLRQVGSLIEILMGGGYQHQYCQK---------LSPGK-SLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVD----NSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXX-XXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEYLN 2439
            S+  +  + +WI+    K EC    P  K    C CGR   +H+            KN+   S + I++E W+I  +T   PTDA+GT+EFQGG H  KA YVR+S+ T P  +LHL+ +EW L +P L+IS+ GGL NF+LQPKLK+VF  GL+KAA TTG W+ T G++TGV +HVG+ALK+        I  +GI+PWGIV++++ L+G++ + PY +++N   K  VLN  H++F+LADNGT  K+GAE+ LRR LE++++ Q I    + R+G+  VPVVA++VEGG     +V E + D  PVPVVVC+GSGRA+D+LAF H+YS+E G +   +R+Q+L T+Q+TF+    +A+ L+  +  C+K++ELITV+RM  +G  DID+AILTALL+ +    +  DQL+L +AWNR DIARSQIF    +W    L+ AM+DAL+ DR+DFVKLL+ENGV+MHRFL +SRLE  YN R        N++   V ++KK  +     ++L  +G +IE LMGG Y+  Y +K           P +   L +  M D +      K   +    E E+ +D      ++F +P+ EL+ W +L +R  MA++    GEE++AK+L+A         +  + D   +  +EL      F  L+V L D  YK + +   +LL YEL+ +S  T + LA   + + F+ H C+Q +L D+W G LR  K  GLKV++ +L        LP ++L+L      EFK K ++    Q  E +L 
Sbjct:   54 SVRLLKAQKSWIERAFYKRECVHIIPSTKDPHRCCCGRLIGQHVGLTPSISVLQNEKNESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKI----NTRIGQG-VPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGA--NASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTR----HGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPLRRGRK---TTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGIL--------LPPSILSL------EFKNKDDMPYMSQAQEIHLQ 808          

Query: 3202 KKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYV-HIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPVDFPEESR-------LTPL---AWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGN--VIKRTLQCMDQTQFQIGELHSRFNVMRV 4461
            +KIYEF+ API KF+   +++I  ++L   +  +K  +ER    + +I + +I T  ++  R+   +    + QK+KV  +  WN  D       ++ FSV      Q Q  +                     GR +  +   YW I+ L++    +  G Y+ MI  M+  ++  V+I+ V++ +FGV RQ I++    +     + KNI+  PY+M+YGEV+A +IDP     E+R       L P    AW VP  M  ++L A +++++L+IA   + + ++K  S +V+ + RY +I+ +  RP  PPP II   + ++ + +      C  + K    H + P       D R++  GLKLF++ DE++K+HDFEE+C+E+Y++     D F   N   I+ T + ++    ++ E++ R + M+ 
Sbjct:  860 RKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVK--MERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDL----IAILLFSVGMILRLQDQPFRSD-------------------GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPN--EEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHL------CCRWRK----HESDP-------DERDY--GLKLFITDDELKKVHDFEEQCIEEYFREKD--DRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKA 1244          

Query:  223 NWIDDNILKLECNRFHP--KSNGYCACGRPAEEHIN-----------KNQFHNS-SKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQI-----------------LTLRQVGSLIEILMGGGYQHQYCQK---------LSPGKSLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVD----NSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXX-XXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEYLN 2439
            +WI+    K EC    P  K    C CGR   +H+            KN+   S + I++E W+I  +T   PTDA+GT+EFQGG H  KA YVR+S+ T P  +LHL+ +EW L +P L+IS+ GGL NF+LQPKLK+VF  GL+KAA TTG W+ T G++TGV +HVG+ALK+        I  +GI+PWGIV++++ L+G++ + PY +++N   K  VLN  H++F+LADNGT  K+GAE+ LRR LE++++ Q I    + R+G+  VPVVA++VEGG     +V E + D  PVPVVVC+GSGRA+D+LAF H+YS+E G +   +R+Q+L T+Q+TF+    +A+ L+  +  C+K++ELITV+RM  +G  DID+AILTALL+ +    +  DQL+L +AWNR DIARSQIF    +W    L+ AM+DAL+ DR+DFVKLL+ENGV+MHRFL +SRLE  YN R        N++   V ++KK++                  ++L  +G +IE LMGG Y+  Y +K           P +  +P+             +   +    E E+ +D      ++F +P+ EL+ W +L +R  MA++    GEE++AK+L+A         +  + D   +  +EL      F  L+V L D  YK + +   +LL YEL+ +S  T + LA   + + F+ H C+Q +L D+W G LR  K  GLKV++ +L        LP ++L+L      EFK K ++    Q  E +L 
Sbjct:   65 SWIERAFYKRECVHIIPSTKDPHRCCCGRLIGQHVGLTPSISVLQNEKNESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKI----NTRIGQG-VPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGA--NASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTR----HGPSNTLYHLVRDVKKREYPGFGWIYFKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLR------------RGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGIL--------LPPSILSL------EFKNKDDMPYMSQAQEIHLQ 812          

Query: 3202 KKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYV-HIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPVDFPEESR-------LTPL---AWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGN--VIKRTLQCMDQTQFQIGELHSRFNVMRV 4461
            +KIYEF+ API KF+   +++I  ++L   +  +K  +ER    + +I + +I T  ++  R+   +    + QK+KV  +  WN  D       ++ FSV      Q Q  +                     GR +  +   YW I+ L++    +  G Y+ MI  M+  ++  V+I+ V++ +FGV RQ I++    +     + KNI+  PY+M+YGEV+A +IDP     E+R       L P    AW VP  M  ++L A +++++L+IA   + + ++K  S +V+ + RY +I+ +  RP  PPP II   + ++ + +      C  + K    H + P       D R++  GLKLF++ DE++K+HDFEE+C+E+Y++     D F   N   I+ T + ++    ++ E++ R + M+ 
Sbjct:  864 RKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVK--MERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDL----IAILLFSVGMILRLQDQPFRSD-------------------GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPN--EEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHL------CCRWRK----HESDP-------DERDY--GLKLFITDDELKKVHDFEEQCIEEYFREKD--DRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKA 1248          

Query:  457 YVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQI-----LTLRQVGSLIEILMGGGYQHQYCQK---------LSPGK-SLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVD----NSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXX-XXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEYLN 2439
            YVR+S+ T P  +LHL+ +EW L +P L+IS+ GGL NF+LQPKLK+VF  GL+KAA TTG W+ T G++TGV +HVG+ALK+        I  +GI+PWGIV++++ L+G++ + PY +++N   K  VLN  H++F+LADNGT  K+GAE+ LRR LE++++ Q I    + R+G+  VPVVA++VEGG     +V E + D  PVPVVVC+GSGRA+D+LAF H+YS+E G +   +R+Q+L T+Q+TF+    +A+ L+  +  C+K++ELITV+RM  +G  DID+AILTALL+ +    +  DQL+L +AWNR DIARSQIF    +W    L+ AM+DAL+ DR+DFVKLL+ENGV+MHRFL +SRLE  YN R        N++   V ++KK  +     ++L  +G +IE LMGG Y+  Y +K           P +   L +  M D +      K   +    E E+ +D      ++F +P+ EL+ W +L +R  MA++    GEE++AK+L+A         +  + D   +  +EL      F  L+V L D  YK + +   +LL YEL+ +S  T + LA   + + F+ H C+Q +L D+W G LR  K  GLKV++ +L        LP ++L+L      EFK K ++    Q  E +L 
Sbjct:    2 YVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKI----NTRIGQG-VPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGA--NASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTR----HGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPLRRGRK---TTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGIL--------LPPSILSL------EFKNKDDMPYMSQAQEIHLQ 655          

Query: 3202 KKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYV-HIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEID---------PVDFP-------EESRLTPL------AWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGN--VIKRTLQCMDQTQFQIGELHSRFNVMRV 4461
            +KIYEF+ API KF+   +++I  ++L   +  +K  +ER    + +I + +I T  ++  R+   +    + QK+KV  +  WN  D       ++ FSV      Q Q  +                     GR +  +   YW I+ L++    +  G Y+ MI  M+  ++  V+I+ V++ +FGV RQ I++    +     + KNI+  PY+M+YGEV+A +ID         P   P       E+ ++  L      AW VP  M  ++L A +++++L+IA   + + ++K  S +V+ + RY +I+ +  RP  PPP II   + ++ + +      C  + K    H + P       D R++  GLKLF++ DE++K+HDFEE+C+E+Y++     D F   N   I+ T + ++    ++ E++ R + M+ 
Sbjct:  707 RKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVK--MERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDL----IAILLFSVGMILRLQDQPFRSD-------------------GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPN--EEPSWKLAKNIFYMPYWMIYGEVFADQIDRKQVYDSHTPKSAPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHL------CCRWRK----HESDP-------DERDY--GLKLFITDDELKKVHDFEEQCIEEYFREKD--DRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKA 1103          

Query:  457 YVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQI-----------------LTLRQVGSLIEILMGGGYQHQYCQK---------LSPGKSLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVD----NSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXX-XXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEYLN 2439
            YVR+S+ T P  +LHL+ +EW L +P L+IS+ GGL NF+LQPKLK+VF  GL+KAA TTG W+ T G++TGV +HVG+ALK+        I  +GI+PWGIV++++ L+G++ + PY +++N   K  VLN  H++F+LADNGT  K+GAE+ LRR LE++++ Q I    + R+G+  VPVVA++VEGG     +V E + D  PVPVVVC+GSGRA+D+LAF H+YS+E G +   +R+Q+L T+Q+TF+    +A+ L+  +  C+K++ELITV+RM  +G  DID+AILTALL+ +    +  DQL+L +AWNR DIARSQIF    +W    L+ AM+DAL+ DR+DFVKLL+ENGV+MHRFL +SRLE  YN R        N++   V ++KK++                  ++L  +G +IE LMGG Y+  Y +K           P +  +P+             +   +    E E+ +D      ++F +P+ EL+ W +L +R  MA++    GEE++AK+L+A         +  + D   +  +EL      F  L+V L D  YK + +   +LL YEL+ +S  T + LA   + + F+ H C+Q +L D+W G LR  K  GLKV++ +L        LP ++L+L      EFK K ++    Q  E +L 
Sbjct:    2 YVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKI----NTRIGQG-VPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGA--NASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPS----NTLYHLVRDVKKREYPGFGWIYFKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLR------------RGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGIL--------LPPSILSL------EFKNKDDMPYMSQAQEIHLQ 657          

Query: 3202 KKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYV-HIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPVDFPEESR-------LTPL---AWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGN--VIKRTLQCMDQTQFQIGELHSRFNVMRV 4461
            +KIYEF+ API KF+   +++I  ++L   +  +K  +ER    + +I + +I T  ++  R+   +    + QK+KV  +  WN  D       ++ FSV      Q Q  +                     GR +  +   YW I+ L++    +  G Y+ MI  M+  ++  V+I+ V++ +FGV RQ I++    +     + KNI+  PY+M+YGEV+A +IDP     E+R       L P    AW VP  M  ++L A +++++L+IA   + + ++K  S +V+ + RY +I+ +  RP  PPP II   + ++ + +      C  + K    H + P       D R++  GLKLF++ DE++K+HDFEE+C+E+Y++     D F   N   I+ T + ++    ++ E++ R + M+ 
Sbjct:  709 RKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVK--MERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDL----IAILLFSVGMILRLQDQPFRSD-------------------GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPN--EEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHL------CCRWRK----HESDP-------DERDY--GLKLFITDDELKKVHDFEEQCIEEYFREKD--DRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKA 1093          

Query:  223 NWIDDNILKLECNRFHPKS--NGYCACGRPAEEHI--------NKNQ--------------------FHNSSKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEI-HIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQILTLRQVGSLIEILMGGGYQHQYCQKLSPGKSLL------------------------PVTDMCD------TLSSVDNFKNLYSNSLN-----------------ENEIGVDNSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXXXXX-XXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEY 2433
            NWI+  +   +C+ F P    +  C CG+   +H         NKN                       N   +    W+I  +T   PTDAYG + F+G  H   A+Y RIS+ + P D++HL+++ W L+ P L+I+I GGL  FDLQPKL + F  G++K AK+T  W++T+GLD GV KH+  AL +   H   N++VA+GI+ WG+++ R   +GK+    Y +    N +   LN +H+YFL +DNGTV+++GAEI++R+ LE YLA         G   +S +P+V V++EGG    ++V + VT    +PV+VC+GSGRAAD+LAF H+   + G L  ++R Q++  V+R F   P+ A+ L K++  C   + L+T++R+ E    D+D  I++ LL+     L+  +QL L +AWNR DIAR++IF   TEW +  L NAMI+AL NDR+DFV LLLENGV+M +FL   RLE+ YN      D    + +     +  K  + L +VG L+E LMG  Y+  Y ++    +  L                        P  D          +S ++N +N   +  N                 E E  +D +  FRYPY++L+ W +LT+R  MA  M   GEE +AK+L+A +L +   K       E    ++   + ++F  L+V + ++C KH  ++T RLL  EL  +   T +SLA     + FL H C Q +L+DLW GGL        KVL  L +   IF              L+ FKTK++L LQP+T  E+
Sbjct:  104 NWIECRLKMRQCSYFVPSQRFSERCGCGKERSKHTEEVLERSQNKNHPLNHLTLPGIHEVDTTDADADDNEVNLTPGRWSIQSHTEIVPTDAYGNIVFEGTAH--HAQYARISFDSDPRDIVHLMMKVWKLKPPKLIITINGGLTKFDLQPKLARTFRKGIMKIAKSTDAWIITSGLDEGVVKHLDSALHDHGNHTSKNHVVAIGIASWGMLKQRSRFVGKDSTVTYATNVFNNTRLKELNDNHSYFLFSDNGTVNRYGAEIIMRKRLEAYLA--------QGDKKRSAIPLVCVVLEGGAFTIKMVHDYVTTIPRIPVIVCDGSGRAADILAFAHQAVSQNGFLSDNIRNQLVNIVRRIFGYDPKTAQKLIKQIVECSTNKSLMTIFRLGESSREDLDHVIMSCLLKGQ--NLSPPEQLQLALAWNRADIARTEIFANGTEWTTQDLHNAMIEALSNDRIDFVHLLLENGVSMQKFLTYGRLEHLYNT-----DKGPQNTLRTNLLVDSKHHIKLVEVGRLVENLMGNLYKSNYTKEEFKNQYFLFNNRKQFGKRVHSNSNGGRNDVIGPSGDAGRERMSSMQISLINNARNSIISLFNGGGRKRESDDEDDFSNLEEEANMDFT--FRYPYSDLMIWAVLTKRQKMAKLMWTHGEEGMAKALVASRLYVSLAKTASLATGEIGMSQDFTEFSDEFSELAVEVLEYCTKHGRDQTLRLLTCELANWGDETCLSLAANNGHRKFLAHPCCQMLLSDLWQGGLLMKNNQNSKVLTCLAAPPLIF--------------LLGFKTKEQLMLQPKTAAEH 887          

Query: 3169 QISPGTQLSCRKKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERI-DYFELYIYVHIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEID---------------PVDFPEESRLT--PLAWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIIL---VWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVED 4332
            Q+     LS +KKI EF+ APIT ++L   + I  +ILL     +K   +RI  + E Y++ +I    L+  RK  +T  ++ ++ +         FF +  G   L+AF +  +    F ++   T     TL           GR LII  S  W +K ++ +   +  G Y+ ++  MI  ++P  +++ + + AFG++RQ I Y       I  +++NI+L+PYFMLYGEVYAAEID               P+     +  T  P  W  P+ + +FML+  V+++++++AG T I+ K  +S+ +++++ RY  +++YES P+ PPPF I+   +W++ L+K            F+RK           N FD       LKLFLS DE+EK+H FEEE VED
Sbjct: 1057 QVYTQRPLSWKKKIMEFYKAPITTYWLWFFAFIWFLILLTYNLLVK--TQRIASWSEWYVFAYIFVWTLEIGRKVVSTIMMDTSKPVLKQLRVF--FFQYRNG---LLAFGLLTYLIAYFIRLSPTTK----TL-----------GRILIICNSVIWSLKLVDYLSVQQGLGPYINIVAEMIPTMIPLCVLVFITLYAFGLLRQSITYPYEDWHWI--LVRNIFLQPYFMLYGEVYAAEIDTCGDEIWQTHEDENIPISMLNVTHETCVPGYWIAPVGLTVFMLATNVLLMNVMVAGCTYIFEKHIQSTREIFLFERYGQVMEYESTPWLPPPFTIIYHVIWLFKLIKS-------SSRMFERK-----------NLFDQ-----SLKLFLSPDEMEKVHTFEEESVED 1418          

Query:  226 WIDDNILKLECNRFH--PKSNGYCACGRPAEEHINKNQFHNSSKI-----KNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKG---NNIVALGISPWGIVQHRKHLLGKEKICPYYSI--ANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQILTLRQVGSLIEILMGGGYQHQYCQKLSPGK-------SLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVDNSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXXXXXXXXXXXXXXXDNESEYL---EELKLWGNKFEVL--SVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIF 2331
            WI++   K EC RF   PK    C CGRP   H   + F ++  +     + + W I +NT    TDA+GT+ FQGG H  KA+YVR+SY + P DV++L+ + W L  P LVI++ GG++NF+L+ +L ++F  G++KAA+TTG W++T+GLD+GV +HV +AL +E  I     + IV +GI+PWG+++ RK  L ++    YY +   + N    +LN  H+YFLLADNGTV +FGA++ LR++LE ++AT       +GR    +VPVV  L+EGG+ +   + + VT +  +P +VC+GSGRAAD+++F  RY + +G    +V E++   ++  F     + E +++++  C+ R +L+ ++R  ++   D+D  IL+ +LQ+    L   +QL LT++WNR D+A+S +F    +W S VL+ AM DAL  DR+DFV+ LLENGV+M  FL ++RLE  YN+  +    S  + +    ++     LT+  +G ++E LMG  +Q  Y  +   GK       +          +   + FK    + +N+NE   +   +F YP+ +LL W +LT R+ MA  M + GE+++AK L+A++L K   K+     E EYL   E  +L+ N  +    ++ L D CY+ + + T RLL  EL  +  +  +SLA L  +K FL H C Q +L +LW+G L+      ++VL  L+   AI 
Sbjct:   88 WIENTFEKRECIRFAALPKDPERCGCGRPLSAHTPASTFFSTLPVHLLEKEQQTWTIANNTQTSTTDAFGTIVFQGGAHAHKAQYVRLSYDSEPLDVMYLMEKVWGLEAPRLVITVHGGMSNFELEERLGRLFRKGMLKAAQTTGAWIITSGLDSGVVRHVAKAL-DEAGISARMRSQIVTIGIAPWGVIK-RKERLIRQNEHVYYDVHSLSVNANVGILNDRHSYFLLADNGTVGRFGADLHLRQNLENHIAT----FGCNGR----KVPVVCTLLEGGISSINAIHDYVTMKPDIPAIVCDGSGRAADIISFAARYINSDGTFAAEVGEKLRNLIKMVFP--ETDQEEMFRKITECVIRDDLLRIFRYGQEEEEDVDFVILSTVLQKQ--NLPPDEQLALTLSWNRVDLAKSCLFSNGRKWSSDVLEKAMNDALYWDRVDFVECLLENGVSMKNFLSINRLENLYNMDDINSAHSVRNWMENFDSMDPHTYLTIPMIGQVVEKLMGNAFQLYYTSRSFKGKYDRYKRINQSSYFHRKRKIVQKELFKKKSDDQINDNE---EEDFSFAYPFNDLLIWAVLTSRHGMAECMWVHGEDAMAKCLLAIRLYKATAKIA----EDEYLDVEEAKRLFDNAVKCREDAIELLDQCYRADHDRTLRLLRMELPHWGNNNCLSLAVLANTKTFLAHPCCQILLAELWHGSLKVRSGSNVRVLTALICPPAIL 793          

Query: 3187 QLSCRKKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYVHIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPVDFPEESRLTPLAWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVE 4329
            QL+  ++   F+ +PITKF+   I+ ++ +     +  ++ S++   Y E   +++ +T  ++H RK   + G  I +K+KV +   +N +  +   + L+ +  R    Y+                         WGR L+   +  + +K  E +    L G Y++M   M+  +    ++L V + AFGV RQ +    V D     +++NI+ KPYFMLYGEVYA EID     E  R  P  +  PL MV+F+L A +++L+L+IA   +IY    E S +++++ RY  +++Y   PF PPPF I   +Y  +  +Y               +  +P       +H      +KL ++ DE++++ DFEE+C++
Sbjct:  882 QLNKFERFRAFYSSPITKFWSWCIAFLIFLTTQTCILLLETSLKPSKY-EWITFIYTVTLSVEHIRKLMTSEGSRINEKVKVFYAKWYNIWTSAALLFFLVGYGFRLVPMYRHS-----------------------WGRVLLSFSNVLFYMKIFEYLSVHPLLGPYIQMAAKMVWSMCYICVLLLVPLMAFGVNRQALTEPNVKDWH-WLLVRNIFYKPYFMLYGEVYAGEIDTCG-DEGIRCFPGYFIPPLLMVIFLLVANILLLNLLIAIFNNIYNDSIEKSKEIWLFQRYQQLMEYHDSPFLPPPFSIFAHVYHFIDYLY---------------NLRRPDTKRFRSEH-----SIKLSVTEDEMKRIQDFEEDCID 1216          

Query:  184 KSNRSLSTVSEKYNWIDDNILKLECNRFHPKSNGY--CACGRPAEEHIN-------------------------------KNQFHNSSKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQILTLRQVGSLIEILMGGGYQHQY 1731
            +SN SL+    ++NW+ +   + EC+RF   S     C CGR  + H N                                 Q   + +  NE W++  +T    T+A+G +EFQGGPHP KA+YVR+++ T P  ++ L    W +  P L+I++ GG +NFDLQPKL +VF  GL+KAA TTG W++T+G DTGV KHV  AL+     + N IV +GI+PWG+++ R+  +G++K  PYY  ++K +    LN  H+YFLL DNGTV ++GAE++LR+ LE Y++    + +  G  G   VPVV V++EGG    R V + VT+   VPVVVC+GSGRAADLLAF H+   E+G LP D+R QVL  V+ TF      A  L  E+ +C + + L+T++R+ E G  D+D AILTALL+     L+ ADQL L +AWNR DIARS +F +  EW    L NAM++ALI+DR+DFV+LLLE G+NM +FL +SRL+  YN      +  F  ++  V  +++     L  +G +IE LMG  YQ  Y
Sbjct:  173 ESNMSLN----RHNWVRETFTRRECSRFIASSRDLHKCGCGRTRDAHRNIPELTSEFLRQKRSVAALEQQRSISNVNDDINTQNMYTKRGANEKWSLRKHTVSLATNAFGQVEFQGGPHPYKAQYVRVNFDTEPAYIMSLFEHVWQISPPRLIITVHGGTSNFDLQPKLARVFRKGLLKAASTTGAWIITSGCDTGVVKHVAAALEGAQSAQRNKIVCIGIAPWGLLKKREDFIGQDKTVPYYPSSSKGRFTG-LNNRHSYFLLVDNGTVGRYGAEVILRKRLEMYISQ---KQKIFG--GTRSVPVVCVVLEGGSCTIRSVLDYVTNVPRVPVVVCDGSGRAADLLAFAHQNVTEDGLLPDDIRRQVLLLVETTFGCSEAAAHRLLHELTVCAQHKNLLTIFRLGEQGEHDVDHAILTALLKGQ--NLSAADQLALALAWNRVDIARSDVFAMGHEWPQAALHNAMMEALIHDRVDFVRLLLEQGINMQKFLTISRLDELYNTDKGPPNTLF-YIVRDVVRVRQGYRFKLPDIGLVIEKLMGNSYQCSY 709          

Query: 3073 TDMSHRASVTF-NNLSFTKCAPDALFEFCQENP--QISPGTQLSCRKKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYVHIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEID---------------PVDFPEES---RLTPLAWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVED 4332
            +DMS  +SV F ++ + +K     +    + NP  Q     ++  R++ YEF+ API+ F+   IS IL I        +K +  R    E  +  ++    L+  RK   +      +K++ +  S WN        + ++ F +R F +  +                         GR ++   S  W +K L+ M      G Y+ M   MI+ +   +++L V + +FG+ RQ I Y       I  +++NI+LKPYFMLYGEVYA EID               PV     +      P  W  PL M  F+L A ++++S++IA    I+    E S +++++ RY  +++YES PF PPP   L    ++L+            F R     +K    +  FD       LKLFL  D+IEKLHDFEE+C+ED
Sbjct: 1150 SDMSKTSSVIFGSDPNLSKLQKSNITSTDRPNPMEQFQGTRKIKMRRRFYEFYSAPISTFWSWTISFILFITFFTYTLLVK-TPPRPTVIEYILIAYVAAFGLEQVRKIIMSDAKPFYEKIRTYVCSFWNCVTILAIIFYIVGFFMRCFGSVAY-------------------------GRVILACDSVLWTMKLLDYMSVHPKLGPYVTMAGKMIQNMSYIIVMLVVTLLSFGLARQSITYPDETWHWI--LVRNIFLKPYFMLYGEVYADEIDTCGDEAWDQHLENGGPVILGNGTTGLSCVPGYWIPPLLMTFFLLIANILLMSMLIAIFNHIFDATDEMSQQIWLFQRYKQVMEYESTPFLPPPLTPLYHGVLILQ------------FVRTRLSCSKSQERNPMFDF-----SLKLFLDNDQIEKLHDFEEDCMED 1545          

Query: 1828 SLNENEIGVDNSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXXXXXXXXXXXXXXXDN-ESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEYLN 2439
            SL     G     +FRYPY+EL+ W +LT+R DMAM M   GEE++AK+L+A +L K +      D  E E  EELK +  +F +LS+ L DHCY  +  +T +LL YEL  +S  T ++LA +  +K FL H C Q +L DLW+GGLR      +KV++ L+    I              +++EFKT++EL  QPQT  E+ N
Sbjct:  834 SLTSASDGSQTEPDFRYPYSELMIWAVLTKRQDMAMCMWQHGEEAMAKALVACRLYKSLATEAAEDYLEVEICEELKKYAEEFRILSLELLDHCYHVDDAQTLQLLTYELSNWSNETCLALAVIVNNKHFLAHPCCQILLADLWHGGLRMRTHSNIKVVLGLICPPFI--------------QMLEFKTREELLNQPQTAAEHQN 1024          

Query:  184 KSNRSLSTVSEKYNWIDDNILKLECNRFHPKSNGY--CACGRPAEEHIN-------------------------------KNQFHNSSKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQILTLRQVGSLIEILMGGGYQHQY 1731
            +SN SL+    ++NW+ +   + EC+RF   S     C CGR  + H N                                 Q   + +  NE W++  +T    T+A+G +EFQGGPHP KA+YVR+++ T P  ++ L    W +  P L+I++ GG +NFDLQPKL +VF  GL+KAA TTG W++T+G DTGV KHV  AL+     + N IV +GI+PWG+++ R+  +G++K  PYY  ++K +    LN  H+YFLL DNGTV ++GAE++LR+ LE Y++    + +  G  G   VPVV V++EGG    R V + VT+   VPVVVC+GSGRAADLLAF H+   E+G LP D+R QVL  V+ TF      A  L  E+ +C + + L+T++R+ E G  D+D AILTALL+     L+ ADQL L +AWNR DIARS +F +  EW    L NAM++ALI+DR+DFV+LLLE G+NM +FL +SRL+  YN      +  F  ++  V  +++     L  +G +IE LMG  YQ  Y
Sbjct:  274 ESNMSLN----RHNWVRETFTRRECSRFIASSRDLHKCGCGRTRDAHRNIPELTSEFLRQKRSVAALEQQRSISNVNDDINTQNMYTKRGANEKWSLRKHTVSLATNAFGQVEFQGGPHPYKAQYVRVNFDTEPAYIMSLFEHVWQISPPRLIITVHGGTSNFDLQPKLARVFRKGLLKAASTTGAWIITSGCDTGVVKHVAAALEGAQSAQRNKIVCIGIAPWGLLKKREDFIGQDKTVPYYPSSSKGRFTG-LNNRHSYFLLVDNGTVGRYGAEVILRKRLEMYISQ---KQKIFG--GTRSVPVVCVVLEGGSCTIRSVLDYVTNVPRVPVVVCDGSGRAADLLAFAHQNVTEDGLLPDDIRRQVLLLVETTFGCSEAAAHRLLHELTVCAQHKNLLTIFRLGEQGEHDVDHAILTALLKGQ--NLSAADQLALALAWNRVDIARSDVFAMGHEWPQAALHNAMMEALIHDRVDFVRLLLEQGINMQKFLTISRLDELYNTDKGPPNTLF-YIVRDVVRVRQGYRFKLPDIGLVIEKLMGNSYQCSY 810          

Query: 3073 TDMSHRASVTF-NNLSFTKCAPDALFEFCQENP--QISPGTQLSCRKKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYVHIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEID---------------PVDFPEES---RLTPLAWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVED 4332
            +DMS  +SV F ++ + +K     +    + NP  Q     ++  R++ YEF+ API+ F+   IS IL I        +K +  R    E  +  ++    L+  RK   +      +K++ +  S WN        + ++ F +R F +  +                         GR ++   S  W +K L+ M      G Y+ M   MI+ +   +++L V + +FG+ RQ I Y       I  +++NI+LKPYFMLYGEVYA EID               PV     +      P  W  PL M  F+L A ++++S++IA    I+    E S +++++ RY  +++YES PF PPP   L    ++L+            F R     +K    +  FD       LKLFL  D+IEKLHDFEE+C+ED
Sbjct: 1251 SDMSKTSSVIFGSDPNLSKLQKSNITSTDRPNPMEQFQGTRKIKMRRRFYEFYSAPISTFWSWTISFILFITFFTYTLLVK-TPPRPTVIEYILIAYVAAFGLEQVRKIIMSDAKPFYEKIRTYVCSFWNCVTILAIIFYIVGFFMRCFGSVAY-------------------------GRVILACDSVLWTMKLLDYMSVHPKLGPYVTMAGKMIQNMSYIIVMLVVTLLSFGLARQSITYPDETWHWI--LVRNIFLKPYFMLYGEVYADEIDTCGDEAWDQHLENGGPVILGNGTTGLSCVPGYWIPPLLMTFFLLIANILLMSMLIAIFNHIFDATDEMSQQIWLFQRYKQVMEYESTPFLPPPLTPLYHGVLILQ------------FVRTRLSCSKSQERNPMFDF-----SLKLFLDNDQIEKLHDFEEDCMED 1646          

Query: 1828 SLNENEIGVDNSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXXXXXXXXXXXXXXXDN-ESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEYLN 2439
            SL     G     +FRYPY+EL+ W +LT+R DMAM M   GEE++AK+L+A +L K +      D  E E  EELK +  +F +LS+ L DHCY  +  +T +LL YEL  +S  T ++LA +  +K FL H C Q +L DLW+GGLR      +KV++ L+    I              +++EFKT++EL  QPQT  E+ N
Sbjct:  935 SLTSASDGSQTEPDFRYPYSELMIWAVLTKRQDMAMCMWQHGEEAMAKALVACRLYKSLATEAAEDYLEVEICEELKKYAEEFRILSLELLDHCYHVDDAQTLQLLTYELSNWSNETCLALAVIVNNKHFLAHPCCQILLADLWHGGLRMRTHSNIKVVLGLICPPFI--------------QMLEFKTREELLNQPQTAAEHQN 1125          

Query:  184 KSNRSLSTVSEKYNWIDDNILKLECNRFHPKSNGY--CACGRPAEEHIN-------------------------------KNQFHNSSKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQILTLRQVGSLIEILMGGGYQHQY 1731
            +SN SL+    ++NW+ +   + EC+RF   S     C CGR  + H N                                 Q   + +  NE W++  +T    T+A+G +EFQGGPHP KA+YVR+++ T P  ++ L    W +  P L+I++ GG +NFDLQPKL +VF  GL+KAA TTG W++T+G DTGV KHV  AL+     + N IV +GI+PWG+++ R+  +G++K  PYY  ++K +    LN  H+YFLL DNGTV ++GAE++LR+ LE Y++    + +  G  G   VPVV V++EGG    R V + VT+   VPVVVC+GSGRAADLLAF H+   E+G LP D+R QVL  V+ TF      A  L  E+ +C + + L+T++R+ E G  D+D AILTALL+     L+ ADQL L +AWNR DIARS +F +  EW    L NAM++ALI+DR+DFV+LLLE G+NM +FL +SRL+  YN      +  F  ++  V  +++     L  +G +IE LMG  YQ  Y
Sbjct:  213 ESNMSLN----RHNWVRETFTRRECSRFIASSRDLHKCGCGRTRDAHRNIPELTSEFLRQKRSVAALEQQRSISNVNDDINTQNMYTKRGANEKWSLRKHTVSLATNAFGQVEFQGGPHPYKAQYVRVNFDTEPAYIMSLFEHVWQISPPRLIITVHGGTSNFDLQPKLARVFRKGLLKAASTTGAWIITSGCDTGVVKHVAAALEGAQSAQRNKIVCIGIAPWGLLKKREDFIGQDKTVPYYPSSSKGRFTG-LNNRHSYFLLVDNGTVGRYGAEVILRKRLEMYISQ---KQKIFG--GTRSVPVVCVVLEGGSCTIRSVLDYVTNVPRVPVVVCDGSGRAADLLAFAHQNVTEDGLLPDDIRRQVLLLVETTFGCSEAAAHRLLHELTVCAQHKNLLTIFRLGEQGEHDVDHAILTALLKGQ--NLSAADQLALALAWNRVDIARSDVFAMGHEWPQAALHNAMMEALIHDRVDFVRLLLEQGINMQKFLTISRLDELYNTDKGPPNTLF-YIVRDVVRVRQGYRFKLPDIGLVIEKLMGNSYQCSY 749          

Query: 3073 TDMSHRASVTF-NNLSFTKCAPDALFEFCQENP--QISPGTQLSCRKKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYVHIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEID---------------PVDFPEES---RLTPLAWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVED 4332
            +DMS  +SV F ++ + +K     +    + NP  Q     ++  R++ YEF+ API+ F+   IS IL I        +K +  R    E  +  ++    L+  RK   +      +K++ +  S WN        + ++ F +R F +  +                         GR ++   S  W +K L+ M      G Y+ M   MI+ +   +++L V + +FG+ RQ I Y       I  +++NI+LKPYFMLYGEVYA EID               PV     +      P  W  PL M  F+L A ++++S++IA    I+    E S +++++ RY  +++YES PF PPP   L    ++L+            F R     +K    +  FD       LKLFL  D+IEKLHDFEE+C+ED
Sbjct: 1190 SDMSKTSSVIFGSDPNLSKLQKSNITSTDRPNPMEQFQGTRKIKMRRRFYEFYSAPISTFWSWTISFILFITFFTYTLLVK-TPPRPTVIEYILIAYVAAFGLEQVRKIIMSDAKPFYEKIRTYVCSFWNCVTILAIIFYIVGFFMRCFGSVAY-------------------------GRVILACDSVLWTMKLLDYMSVHPKLGPYVTMAGKMIQNMSYIIVMLVVTLLSFGLARQSITYPDETWHWI--LVRNIFLKPYFMLYGEVYADEIDTCGDEAWDQHLENGGPVILGNGTTGLSCVPGYWIPPLLMTFFLLIANILLMSMLIAIFNHIFDATDEMSQQIWLFQRYKQVMEYESTPFLPPPLTPLYHGVLILQ------------FVRTRLSCSKSQERNPMFDF-----SLKLFLDNDQIEKLHDFEEDCMED 1585          

Query: 1828 SLNENEIGVDNSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXXXXXXXXXXXXXXXDN-ESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEYLN 2439
            SL     G     +FRYPY+EL+ W +LT+R DMAM M   GEE++AK+L+A +L K +      D  E E  EELK +  +F +LS+ L DHCY  +  +T +LL YEL  +S  T ++LA +  +K FL H C Q +L DLW+GGLR      +KV++ L+    I              +++EFKT++EL  QPQT  E+ N
Sbjct:  874 SLTSASDGSQTEPDFRYPYSELMIWAVLTKRQDMAMCMWQHGEEAMAKALVACRLYKSLATEAAEDYLEVEICEELKKYAEEFRILSLELLDHCYHVDDAQTLQLLTYELSNWSNETCLALAVIVNNKHFLAHPCCQILLADLWHGGLRMRTHSNIKVVLGLICPPFI--------------QMLEFKTREELLNQPQTAAEHQN 1064          

Query:  223 NWIDDNILKLECNRF--HPKSNGYCACGRPAEEHINKNQFHNSSKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELP--PDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM----EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKV-CNLKKKQILTLRQVGSLIEILMGGGYQHQYC-QKLSP--GKSLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVDNSSN---FRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXXXXXXXXXXXXXXXDN-ESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEYL 2436
            +WI+ N  K EC +F   PK +  C CG+    H       + S    + W    +T P PTDAYGT+EFQGG HPTKA+YVR+S+ T P  ++ L  +EWNL +P L+I++ GG ANFDLQ KLKK    GL+KAAKTTG W+ T G +TGVTK VG+AL  E   +   +V++GI+PWGIV+    LLG  +  P +SI++   K AVLN  H YFLL DNGT  K+GAE++LRR LE++++   +    H     S  PVV +++EGG    R V E VTD  PVPVVVC+GSGRAADLLAF+H+Y+ +  E P    +R+ ++ T+Q+TF +   ++E LY+E+  C + + LITV+R+    E    ++D  ILTAL +     L+  +QL+L + WNR DIARS+IF    EW +  LD AM+ AL +DR+DFVKLLLENGV+M +FL + RLE  YN +    + +   ++  V  ++ K  I TL  +G +I  LMGG Y+  Y  +K  P   K +    + C   S+    +   +NSL+     +  +S    F +P+ ELL W +LT+R  MA+ M   GEE++AKSL++ KL K M      D+ ++E  EEL+ +  +FE     L D  Y+ + E+ +RLL  EL  +S  + +SLA     +  L H C+Q IL DLW GGLR  K    KV++ L        A+P  +      R ++FK+K+EL   PQT EE+L
Sbjct:   14 SWIETNFQKRECIKFIPCPKDDTKCCCGQAQITHQTIPGIESGSP--GDLWLPTKHTRPQPTDAYGTIEFQGGAHPTKAQYVRLSFDTRPELLVQLFTKEWNLELPKLLITVQGGKANFDLQAKLKKEIRKGLLKAAKTTGAWIFTGGTNTGVTKQVGDALLLEGQQRTGRVVSIGIAPWGIVERNHELLGHNREVPCHSISSPRSKLAVLNNRHAYFLLVDNGTQAKYGAELILRRKLEKFISNLKLHPFTH-----SSTPVVCLVIEGGTNTIRAVLEYVTDSPPVPVVVCDGSGRAADLLAFVHKYASDGEEQPVLESMRDYLIGTIQKTFEVGLDQSEKLYQELLQCTRNKNLITVFRIQEKPEGEAQELDQTILTALFKSQ--HLSPPEQLSLALTWNRVDIARSEIFVYGQEWPNGALDEAMMQALEHDRIDFVKLLLENGVSMKKFLTIPRLEELYNTKHGPAN-TLGYILRDVRPHIPKGYIYTLHDIGLVINKLMGGAYRSYYTRRKFRPIYAKVMNSYANACRKSSTYQYQRYAGANSLSLVTGLLPFTSEMALFEFPFNELLIWAVLTKRQQMALLMWTHGEEALAKSLVSCKLYKAMAHEAAEDDLDTEIYEELRSYAKEFESKGNKLLDFSYRQDAEKAQRLLTCELHSWSNQSCLSLAVAANHRALLAHPCSQVILADLWMGGLRTRKNTNFKVILGL--------AMPFYI------RQLDFKSKEELQQMPQTEEEHL 743          

Query: 3190 LSCRKKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYF-ELYIYVHIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPV--DFPEESRLTPLAWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLK 4149
            L  +KK YEF+ APITKF+ + I+++  +I+      +K  +E++  + E Y   +I T   +  R+  ++  + I  K  V   ++WN  D +     +I  + R+                       N  +I   GR +  + S YW ++ L ++   +  G  + M+  M+K ++  V++L+V++ +FGV RQ I+Y         +++K +  +PYFMLYGEV+A +IDP   + P +       W  P+ M +++L A +++++L+IA   +I+ ++   S +V+M+ R+ ++++Y+ +P  PPPFI L   Y LLK
Sbjct:  809 LRLKKKFYEFYTAPITKFWADSIAYMFFLIMFSFTVLVK--MEQMPRWQEWYSIAYITTLGFEKVREIISSEPVAITHKFSVWAWNMWNPCDGAAIILFVIGLAFRF---------------------RENTMDI---GRVIYCVDSIYWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLAVVLMSFGVSRQAILYPN--KQPTWSLIKEVTFQPYFMLYGEVFAGDIDPPCGEDPSQPGCVTGHWVTPITMSMYLLIANILLINLLIAVFNNIFNEVNSVSHQVWMFQRFTVVMEYQQKPVLPPPFIALCHFYSLLK 1103          

Query:  223 NWIDDNILKLECNRF--HPKSNGYCACGRPAEEHINKNQFHNSSKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELP--PDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM----EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQILTLRQVGSLIEILMGGGYQHQYC-QKLSP--GKSLLPVTDMCDTLSSVDNFKNLYSNSLN--------ENEIGVDNSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXXXXXXXXXXXXXXXDN-ESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEYL 2436
            +WI+ N  K EC +F   PK +  C CG+    H       + S    + W    +T P PTDAYGT+EFQGG HPTKA+YVR+S+ T P  ++ L  +EWNL +P L+I++ GG ANFDLQ KLKK    GL+KAAKTTG W+ T G +TGVTK VG+AL  E   +   +V++GI+PWGIV+    LLG  +  P +SI++   K AVLN  H YFLL DNGT  K+GAE++LRR LE++++   +    H     S  PVV +++EGG    R V E VTD  PVPVVVC+GSGRAADLLAF+H+Y+ +  E P    +R+ ++ T+Q+TF +   ++E LY+E+  C + + LITV+R+    E    ++D  ILTAL +     L+  +QL+L + WNR DIARS+IF    EW +  LD AM+ AL +DR+DFVKLLLENGV+M +FL + RLE  YN +    +     +     ++ K  I TL  +G +I  LMGG Y+  Y  +K  P   K +    + C   S+    +   +NSL+         +E+ +     F +P+ ELL W +LT+R  MA+ M   GEE++AKSL++ KL K M      D+ ++E  EEL+ +  +FE     L D  Y+ + E+ +RLL  EL  +S  + +SLA     +  L H C+Q IL DLW GGLR  K    KV++ L        A+P  +      R ++FK+K+EL   PQT EE+L
Sbjct:   14 SWIETNFQKRECIKFIPCPKDDTKCCCGQAQITHQTIPGIESGSP--GDLWLPTKHTRPQPTDAYGTIEFQGGAHPTKAQYVRLSFDTRPELLVQLFTKEWNLELPKLLITVQGGKANFDLQAKLKKEIRKGLLKAAKTTGAWIFTGGTNTGVTKQVGDALLLEGQQRTGRVVSIGIAPWGIVERNHELLGHNREVPCHSISSPRSKLAVLNNRHAYFLLVDNGTQAKYGAELILRRKLEKFISNLKLHPFTH-----SSTPVVCLVIEGGTNTIRAVLEYVTDSPPVPVVVCDGSGRAADLLAFVHKYASDGEEQPVLESMRDYLIGTIQKTFEVGLDQSEKLYQELLQCTRNKNLITVFRIQEKPEGEAQELDQTILTALFKSQ--HLSPPEQLSLALTWNRVDIARSEIFVYGQEWPNGALDEAMMQALEHDRIDFVKLLLENGVSMKKFLTIPRLEELYNTKHGPANTLGYILRDVRPHIPKGYIYTLHDIGLVINKLMGGAYRSYYTRRKFRPIYAKVMNSYANACRKSSTYQYQRYAGANSLSLVTGLLPFTSEMAL-----FEFPFNELLIWAVLTKRQQMALLMWTHGEEALAKSLVSCKLYKAMAHEAAEDDLDTEIYEELRSYAKEFESKGNKLLDFSYRQDAEKAQRLLTCELHSWSNQSCLSLAVAANHRALLAHPCSQVILADLWMGGLRTRKNTNFKVILGL--------AMPFYI------RQLDFKSKEELQQMPQTEEEHL 743          

Query: 3190 LSCRKKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYF-ELYIYVHIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPV--DFPEESRLTPLAWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGNVIKRTLQCMDQTQFQIGELHSRFNV 4452
            L  +KK YEF+ APITKF+ + I+++  +I+      +K  +E++  + E Y   +I T   +  R+  ++  + I  K  V   ++WN  D +     +I  + R+                       N  +I   GR +  + S YW ++ L ++   +  G  + M+  M+K ++  V++L+V++ +FGV RQ I+Y         +++K +  +PYFMLYGEV+A +IDP   + P +       W  P+ M +++L A +++++L+IA   +I+ ++   S +V+M+ R+ ++++Y+ +P  PPPFI L   Y LLK       +C    K            DN         GLKLFL  D++E+L+DFEEECVE ++   +          +K T + ++    +I +++ + N+
Sbjct:  790 LRLKKKFYEFYTAPITKFWADSIAYMFFLIMFSFTVLVK--MEQMPRWQEWYSIAYITTLGFEKVREIISSEPVAITHKFSVWAWNMWNPCDGAAIILFVIGLAFRF---------------------RENTMDI---GRVIYCVDSIYWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLAVVLMSFGVSRQAILYPN--KQPTWSLIKEVTFQPYFMLYGEVFAGDIDPPCGEDPSQPGCVTGHWVTPITMSMYLLIANILLINLLIAVFNNIFNEVNSVSHQVWMFQRFTVVMEYQQKPVLPPPFIALCHFYSLLK-------YCVRKAKGLEVQR------DN---------GLKLFLEKDDLERLYDFEEECVEGFFHEQEIILNQSTDERVKNTTERVETMSQKIEDINQKENI 1163          

Query:  223 NWIDDNILKLECNRF--HPKSNGYCACGRPAEEHINKNQFHNSSKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELP--PDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM----EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQILTLRQVGSLIEILMGGGYQHQYC-QKLSP--GKSLLPVTDMCDTLSSVDNFKNLYSNSLN--------ENEIGVDNSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXXXXXXXXXXXXXXXDN-ESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEYL 2436
            +WI+ N  K EC +F   PK +  C CG+    H       + S    + W    +T P PTDAYGT+EFQGG HPTKA+YVR+S+ T P  ++ L  +EWNL +P L+I++ GG ANFDLQ KLKK    GL+KAAKTTG W+ T G +TGVTK VG+AL  E   +   +V++GI+PWGIV+    LLG  +  P +SI++   K AVLN  H YFLL DNGT  K+GAE++LRR LE++++   +    H     S  PVV +++EGG    R V E VTD  PVPVVVC+GSGRAADLLAF+H+Y+ +  E P    +R+ ++ T+Q+TF +   ++E LY+E+  C + + LITV+R+    E    ++D  ILTAL +     L+  +QL+L + WNR DIARS+IF    EW +  LD AM+ AL +DR+DFVKLLLENGV+M +FL + RLE  YN +    +     +     ++ K  I TL  +G +I  LMGG Y+  Y  +K  P   K +    + C   S+    +   +NSL+         +E+ +     F +P+ ELL W +LT+R  MA+ M   GEE++AKSL++ KL K M      D+ ++E  EEL+ +  +FE     L D  Y+ + E+ +RLL  EL  +S  + +SLA     +  L H C+Q IL DLW GGLR  K    KV++ L        A+P  +      R ++FK+K+EL   PQT EE+L
Sbjct:   21 SWIETNFQKRECIKFIPCPKDDTKCCCGQAQITHQTIPGIESGSP--GDLWLPTKHTRPQPTDAYGTIEFQGGAHPTKAQYVRLSFDTRPELLVQLFTKEWNLELPKLLITVQGGKANFDLQAKLKKEIRKGLLKAAKTTGAWIFTGGTNTGVTKQVGDALLLEGQQRTGRVVSIGIAPWGIVERNHELLGHNREVPCHSISSPRSKLAVLNNRHAYFLLVDNGTQAKYGAELILRRKLEKFISNLKLHPFTH-----SSTPVVCLVIEGGTNTIRAVLEYVTDSPPVPVVVCDGSGRAADLLAFVHKYASDGEEQPVLESMRDYLIGTIQKTFEVGLDQSEKLYQELLQCTRNKNLITVFRIQEKPEGEAQELDQTILTALFKSQ--HLSPPEQLSLALTWNRVDIARSEIFVYGQEWPNGALDEAMMQALEHDRIDFVKLLLENGVSMKKFLTIPRLEELYNTKHGPANTLGYILRDVRPHIPKGYIYTLHDIGLVINKLMGGAYRSYYTRRKFRPIYAKVMNSYANACRKSSTYQYQRYAGANSLSLVTGLLPFTSEMAL-----FEFPFNELLIWAVLTKRQQMALLMWTHGEEALAKSLVSCKLYKAMAHEAAEDDLDTEIYEELRSYAKEFESKGNKLLDFSYRQDAEKAQRLLTCELHSWSNQSCLSLAVAANHRALLAHPCSQVILADLWMGGLRTRKNTNFKVILGL--------AMPFYI------RQLDFKSKEELQQMPQTEEEHL 750          

Query: 3190 LSCRKKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYVHIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPV--DFPEESRLTPLAWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGNVIKRTLQCMDQTQFQIGELHSRFNV 4452
            L  +KK YEF+ APITKF+ + I+++  +I+      +K   +   + E Y   +I T   +  R+  ++  + I  K  V   ++WN  D +     +I  + R+                       N  +I   GR +  + S YW ++ L ++   +  G  + M+  M+K ++  V++L+V++ +FGV RQ I+Y         +++K +  +PYFMLYGEV+A +IDP   + P +       W  P+ M +++L A +++++L+IA   +I+ ++   S +V+M+ R+ ++++Y+ +P  PPPFI L   Y LLK       +C    K            DN         GLKLFL  D++E+L+DFEEECVE ++   +          +K T + ++    +I +++ + N+
Sbjct:  816 LRLKKKFYEFYTAPITKFWADSIAYMFFLIMFSFTVLVKME-QMPRWQEWYSIAYITTLGFEKVREIISSEPVAITHKFSVWAWNMWNPCDGAAIILFVIGLAFRF---------------------RENTMDI---GRVIYCVDSIYWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLAVVLMSFGVSRQAILYPN--KQPTWSLIKEVTFQPYFMLYGEVFAGDIDPPCGEDPSQPGCVTGHWVTPITMSMYLLIANILLINLLIAVFNNIFNEVNSVSHQVWMFQRFTVVMEYQQKPVLPPPFIALCHFYSLLK-------YCVRKAKGLEVQR------DN---------GLKLFLEKDDLERLYDFEEECVEGFFHEQEIILNQSTDERVKNTTERVETMSQKIEDINQKENI 1189          

Query:  223 NWIDDNILKLECNRF--HPKSNGYCACGRPAEEHINKNQFHNSSKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELP--PDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM----EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQILTLRQVGSLIEILMGGGYQHQYC-QKLSP--GKSLLPVTDMCDTLSSVDNFKNLYSNSLN--------ENEIGVDNSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXXXXXXXXXXXXXXXDN-ESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEYL 2436
            +WI+ N  K EC +F   PK +  C CG+    H       + S    + W    +T P PTDAYGT+EFQGG HPTKA+YVR+S+ T P  ++ L  +EWNL +P L+I++ GG ANFDLQ KLKK    GL+KAAKTTG W+ T G +TGVTK VG+AL  E   +   +V++GI+PWGIV+    LLG  +  P +SI++   K AVLN  H YFLL DNGT  K+GAE++LRR LE++++   +    H     S  PVV +++EGG    R V E VTD  PVPVVVC+GSGRAADLLAF+H+Y+ +  E P    +R+ ++ T+Q+TF +   ++E LY+E+  C + + LITV+R+    E    ++D  ILTAL +     L+  +QL+L + WNR DIARS+IF    EW +  LD AM+ AL +DR+DFVKLLLENGV+M +FL + RLE  YN +    +     +     ++ K  I TL  +G +I  LMGG Y+  Y  +K  P   K +    + C   S+    +   +NSL+         +E+ +     F +P+ ELL W +LT+R  MA+ M   GEE++AKSL++ KL K M      D+ ++E  EEL+ +  +FE     L D  Y+ + E+ +RLL  EL  +S  + +SLA     +  L H C+Q IL DLW GGLR  K    KV++ L        A+P  +      R ++FK+K+EL   PQT EE+L
Sbjct:   14 SWIETNFQKRECIKFIPCPKDDTKCCCGQAQITHQTIPGIESGSP--GDLWLPTKHTRPQPTDAYGTIEFQGGAHPTKAQYVRLSFDTRPELLVQLFTKEWNLELPKLLITVQGGKANFDLQAKLKKEIRKGLLKAAKTTGAWIFTGGTNTGVTKQVGDALLLEGQQRTGRVVSIGIAPWGIVERNHELLGHNREVPCHSISSPRSKLAVLNNRHAYFLLVDNGTQAKYGAELILRRKLEKFISNLKLHPFTH-----SSTPVVCLVIEGGTNTIRAVLEYVTDSPPVPVVVCDGSGRAADLLAFVHKYASDGEEQPVLESMRDYLIGTIQKTFEVGLDQSEKLYQELLQCTRNKNLITVFRIQEKPEGEAQELDQTILTALFKSQ--HLSPPEQLSLALTWNRVDIARSEIFVYGQEWPNGALDEAMMQALEHDRIDFVKLLLENGVSMKKFLTIPRLEELYNTKHGPANTLGYILRDVRPHIPKGYIYTLHDIGLVINKLMGGAYRSYYTRRKFRPIYAKVMNSYANACRKSSTYQYQRYAGANSLSLVTGLLPFTSEMAL-----FEFPFNELLIWAVLTKRQQMALLMWTHGEEALAKSLVSCKLYKAMAHEAAEDDLDTEIYEELRSYAKEFESKGNKLLDFSYRQDAEKAQRLLTCELHSWSNQSCLSLAVAANHRALLAHPCSQVILADLWMGGLRTRKNTNFKVILGL--------AMPFYI------RQLDFKSKEELQQMPQTEEEHL 743          

Query: 3190 LSCRKKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYVHIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPV--DFPEESRLTPLAWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGNVIKRTLQCMDQTQFQIGELHSRFNV 4452
            L  +KK YEF+ APITKF+ + I+++  +I+      +K   +   + E Y   +I T   +  R+  ++  + I  K  V   ++WN  D +     +I  + R+                       N  +I   GR +  + S YW ++ L ++   +  G  + M+  M+K ++  V++L+V++ +FGV RQ I+Y         +++K +  +PYFMLYGEV+A +IDP   + P +       W  P+ M +++L A +++++L+IA   +I+ ++   S +V+M+ R+ ++++Y+ +P  PPPFI L   Y LLK       +C    K            DN         GLKLFL  D++E+L+DFEEECVE ++   +          +K T + ++    +I +++ + N+
Sbjct:  809 LRLKKKFYEFYTAPITKFWADSIAYMFFLIMFSFTVLVKME-QMPRWQEWYSIAYITTLGFEKVREIISSEPVAITHKFSVWAWNMWNPCDGAAIILFVIGLAFRF---------------------RENTMDI---GRVIYCVDSIYWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLAVVLMSFGVSRQAILYPN--KQPTWSLIKEVTFQPYFMLYGEVFAGDIDPPCGEDPSQPGCVTGHWVTPITMSMYLLIANILLINLLIAVFNNIFNEVNSVSHQVWMFQRFTVVMEYQQKPVLPPPFIALCHFYSLLK-------YCVRKAKGLEVQR------DN---------GLKLFLEKDDLERLYDFEEECVEGFFHEQEIILNQSTDERVKNTTERVETMSQKIEDINQKENI 1182          

Query:  223 NWIDDNILKLECNRF--HPKSNGYCACGRPAEEHINKNQFHNSSKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELP--PDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM----EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQILTLRQVGSLIEILMGGGYQHQYC-QKLSP--GKSLLPVTDMCDTLSSVDNFKNLYSNSLN--------ENEIGVDNSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXXXXXXXXXXXXXXXDN-ESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEYL 2436
            +WI+ N  K EC +F   PK +  C CG+    H       + S    + W    +T P PTDAYGT+EFQGG HPTKA+YVR+S+ T P  ++ L  +EWNL +P L+I++ GG ANFDLQ KLKK    GL+KAAKTTG W+ T G +TGVTK VG+AL  E   +   +V++GI+PWGIV+    LLG  +  P +SI++   K AVLN  H YFLL DNGT  K+GAE++LRR LE++++   +    H     S  PVV +++EGG    R V E VTD  PVPVVVC+GSGRAADLLAF+H+Y+ +  E P    +R+ ++ T+Q+TF +   ++E LY+E+  C + + LITV+R+    E    ++D  ILTAL +     L+  +QL+L + WNR DIARS+IF    EW +  LD AM+ AL +DR+DFVKLLLENGV+M +FL + RLE  YN +    +     +     ++ K  I TL  +G +I  LMGG Y+  Y  +K  P   K +    + C   S+    +   +NSL+         +E+ +     F +P+ ELL W +LT+R  MA+ M   GEE++AKSL++ KL K M      D+ ++E  EEL+ +  +FE     L D  Y+ + E+ +RLL  EL  +S  + +SLA     +  L H C+Q IL DLW GGLR  K    KV++ L        A+P  +      R ++FK+K+EL   PQT EE+L
Sbjct:   21 SWIETNFQKRECIKFIPCPKDDTKCCCGQAQITHQTIPGIESGSP--GDLWLPTKHTRPQPTDAYGTIEFQGGAHPTKAQYVRLSFDTRPELLVQLFTKEWNLELPKLLITVQGGKANFDLQAKLKKEIRKGLLKAAKTTGAWIFTGGTNTGVTKQVGDALLLEGQQRTGRVVSIGIAPWGIVERNHELLGHNREVPCHSISSPRSKLAVLNNRHAYFLLVDNGTQAKYGAELILRRKLEKFISNLKLHPFTH-----SSTPVVCLVIEGGTNTIRAVLEYVTDSPPVPVVVCDGSGRAADLLAFVHKYASDGEEQPVLESMRDYLIGTIQKTFEVGLDQSEKLYQELLQCTRNKNLITVFRIQEKPEGEAQELDQTILTALFKSQ--HLSPPEQLSLALTWNRVDIARSEIFVYGQEWPNGALDEAMMQALEHDRIDFVKLLLENGVSMKKFLTIPRLEELYNTKHGPANTLGYILRDVRPHIPKGYIYTLHDIGLVINKLMGGAYRSYYTRRKFRPIYAKVMNSYANACRKSSTYQYQRYAGANSLSLVTGLLPFTSEMAL-----FEFPFNELLIWAVLTKRQQMALLMWTHGEEALAKSLVSCKLYKAMAHEAAEDDLDTEIYEELRSYAKEFESKGNKLLDFSYRQDAEKAQRLLTCELHSWSNQSCLSLAVAANHRALLAHPCSQVILADLWMGGLRTRKNTNFKVILGL--------AMPFYI------RQLDFKSKEELQQMPQTEEEHL 750          

Query: 3190 LSCRKKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYVHIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPV--DFPEESRLTPLAWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGNVIKRTLQCMDQTQFQIGELHSRFNV 4452
            L  +KK YEF+ APITKF+ + I+++  +I+      +K   +   + E Y   +I T   +  R+  ++  + I  K  V   ++WN  D +     +I  + R+                       N  +I   GR +  + S YW ++ L ++   +  G  + M+  M+K ++  V++L+V++ +FGV RQ I+Y         +++K +  +PYFMLYGEV+A +IDP   + P +       W  P+ M +++L A +++++L+IA   +I+ ++   S +V+M+ R+ ++++Y+ +P  PPPFI L   Y LLK       +C    K            DN         GLKLFL  D++E+L+DFEEECVE ++   +          +K T + ++    +I +++ + N+
Sbjct:  841 LRLKKKFYEFYTAPITKFWADSIAYMFFLIMFSFTVLVKME-QMPRWQEWYSIAYITTLGFEKVREIISSEPVAITHKFSVWAWNMWNPCDGAAIILFVIGLAFRF---------------------RENTMDI---GRVIYCVDSIYWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLAVVLMSFGVSRQAILYPN--KQPTWSLIKEVTFQPYFMLYGEVFAGDIDPPCGEDPSQPGCVTGHWVTPITMSMYLLIANILLINLLIAVFNNIFNEVNSVSHQVWMFQRFTVVMEYQQKPVLPPPFIALCHFYSLLK-------YCVRKAKGLEVQR------DN---------GLKLFLEKDDLERLYDFEEECVEGFFHEQEIILNQSTDERVKNTTERVETMSQKIEDINQKENI 1214          

Query:  223 NWIDDNILKLECNRF--HPKSNGYCACGRPAEEH------INKNQFHNSSKIK-----NEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQI-----LTLRQVGSLIEILMGGGYQHQYCQK---------LSPGK-SLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVDNS--SNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXX-XXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEYLN 2439
            +WI+    K EC       K +  C CGR   +H      I+ NQ   S ++      +E W+I  +T   PTDA+GT+EFQGG H  KA YVR+SY T P  +LHL+ +EW L +P L+IS+ GGL NF+LQPKLK+VF  GL+KAA TTG W+ T G++TGV +HVG+ALK+        I  +GI+PWGIV++++ L+GK+ + PY +++N   K  VLN  H++F+LADNGT  K+GAE+ LRR LE++++ Q I    + R+G+  VPVVA++VEGG     +V E + D  PVPVVVC+GSGRA+D+LAF H+YS+E G +   +R+Q+L T+Q+TF+    +A+ L+  +  C+K++ELITV+RM  +G  DID+AILTALL+ +    +  DQL+L +AWNR DIARSQIF    +W    L+ +M+DAL+ DR+DFVKLL+ENGV+MHRFL +SRLE  YN R        N++   V ++KK  +     ++L  +G +IE LMGG Y+  Y +K           P +   L +  M D +      +        E +I +D+   ++F +P+ EL+ W +L +R  MA++    GEE++AK+L+A         +  + D   +  +EL     +F  L+V L D  YK + +   +LL YEL+ +S  T + LA   + + F+ H C+Q +L D+W G LR  K  GLKV+              + LL   S   +EFK K E++  PQ  + YL 
Sbjct:    4 SWIERAFSKRECVHIIVSTKDHHRCCCGRLIGQHVGLPPSISSNQNEKSERVPKNDSLSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSYDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLVGKDVVRPYQTMSNPLSKLTVLNSLHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKI----NTRIGQG-VPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGIINESLRDQLLVTIQKTFTYSRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGA--NASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQSMLDALVLDRVDFVKLLIENGVSMHRFLTLSRLEELYNTR----HGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDMPIRRGRQKTTRKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNQNSREFGQLAVELLDQSYKQDEQMAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVI--------------LGLLLPPSILSLEFKNKDEMSYMPQDQDTYLQ 749          

Query: 3334 ELYIYVHIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPVD----FPEESRLTPL------AWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGN--VIKRTLQCMDQTQFQIGELHSRFNVMRV 4461
            E  +  +I TN ++  R+   +    + QK+KV  +  WN  D       ++ FS+                     L   +P  +  +GR +  +   YW I+ L++    +  G Y+ MI  M+  ++  V+I+ V++ +FGV RQ I+     +     + +NI+  PY+M+YGEV+A +IDP        EE  + PL      AW VP  M  ++L A +++++L+IA   + + ++K  S +V+ + RY +I+ +  RP  PPP II   I ++LK +      C  + K             ++ D R++  GLKLF++ DE++K+HDFEE+C+E+Y++     D F   N   I+ T + ++    ++ E++ R + M+ 
Sbjct:  914 EWIVIAYIFTNGIEKMREILMSEPGKLLQKVKVWLQEYWNITDL----MAILIFSI------------------GMVLRLQDPP-LMSYGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILNPN--EDPSWMLARNIFFMPYWMIYGEVFADQIDPPCGQNITTEEGVVMPLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHITMVLKHL------CCRWRK-------------HDEDERDY--GLKLFITEDELKKVHDFEEQCMEEYFREKD--DRFNSSNDERIRVTSERVENMAMRLEEVNEREHFMKA 1253          

Query:  457 YVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQI-----LTLRQVGSLIEILMGGGYQHQYCQK---------LSPGK-SLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVDNS--SNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXX-XXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEYLN 2439
            YVR+SY T P  +LHL+ +EW L +P L+IS+ GGL NF+LQPKLK+VF  GL+KAA TTG W+ T G++TGV +HVG+ALK+        I  +GI+PWGIV++++ L+GK+ + PY +++N   K  VLN  H++F+LADNGT  K+GAE+ LRR LE++++ Q I    + R+G+  VPVVA++VEGG     +V E + D  PVPVVVC+GSGRA+D+LAF H+YS+E G +   +R+Q+L T+Q+TF+    +A+ L+  +  C+K++ELITV+RM  +G  DID+AILTALL+ +    +  DQL+L +AWNR DIARSQIF    +W    L+ +M+DAL+ DR+DFVKLL+ENGV+MHRFL +SRLE  YN R        N++   V ++KK  +     ++L  +G +IE LMGG Y+  Y +K           P +   L +  M D +      +        E +I +D+   ++F +P+ EL+ W +L +R  MA++    GEE++AK+L+A         +  + D   +  +EL     +F  L+V L D  YK + +   +LL YEL+ +S  T + LA   + + F+ H C+Q +L D+W G LR  K  GLKV+              + LL   S   +EFK K E++  PQ  + YL 
Sbjct:    2 YVRVSYDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLVGKDVVRPYQTMSNPLSKLTVLNSLHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKI----NTRIGQG-VPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGIINESLRDQLLVTIQKTFTYSRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGA--NASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQSMLDALVLDRVDFVKLLIENGVSMHRFLTLSRLEELYNTR----HGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDMPIRRGRQKTTRKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNQNSREFGQLAVELLDQSYKQDEQMAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVI--------------LGLLLPPSILSLEFKNKDEMSYMPQDQDTYLQ 656          

Query: 3202 KKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXK---WSVERIDYFELYIYVHIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPV----DFPEESRLTPL------AWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGN--VIKRTLQCMDQTQFQIGELHSRFNVMRV 4461
            +KIYEF+ API KF+ + ++++  ++L   +  +K   W   +    E  +  +I TN ++  R+   +    + QK+KV  +  WN  D       ++ FS+                     L   +P  +  +GR +  +   YW I+ L++    +  G Y+ MI  M+  ++  V+I+ V++ +FGV RQ I+     +     + +NI+  PY+M+YGEV+A +IDP        EE  + PL      AW VP  M  ++L A +++++L+IA   + + ++K  S +V+ + RY +I+ +  RP  PPP II   I ++LK +      C  + K             ++ D R++  GLKLF++ DE++K+HDFEE+C+E+Y++     D F   N   I+ T + ++    ++ E++ R + M+ 
Sbjct:  720 RKIYEFYNAPIVKFWFHTLAYVGYLMLFNYIVLVKMDLWPSPQ----EWIVIAYIFTNGIEKMREILMSEPGKLLQKVKVWLQEYWNITDL----MAILIFSI------------------GMVLRLQDPP-LMSYGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILNPN--EDPSWMLARNIFFMPYWMIYGEVFADQIDPPCGQNITTEEGVVMPLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHITMVLKHL------CCRWRK-------------HDEDERDY--GLKLFITEDELKKVHDFEEQCMEEYFREKD--DRFNSSNDERIRVTSERVENMAMRLEEVNEREHFMKA 1102          

Query:  394 FPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYR-MEDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIF-----------------GIQTEWQSPV-----------------------------------------LDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLK-GDFSFNSMISKVCNLKKKQILTLRQVGSLIEILMGGGYQHQYCQK-----------LSPGKSLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVDNS--SNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXXXXXXXXXXXXXXXDNESEYL-EELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQ 2412
             PTD+YG +EFQGG H  KA Y+R+SY T P ++LHL++++W L +P L+IS+ GGL NFDLQPKLK+VF  GL+KAA TTG W+ T G+ TGV +HVG+ALK+        + A+GI+PWGIV++++ L+G++   PY +++N   K +VLN  H++F+LADNGT  K+GAE+ LRR LE++++ Q I    + RLG+  VP+V +++EGG     +V E + ++ PVPVVVC+GSGRA+D+++F H+YS+++G +   VR+Q+L T+Q+TF+    +A+ +Y  +  C+K+RELITV+R   +G  DI++AILTALL+ +    +  DQL+L +AWNR DIARSQIF                 G Q + +SP+                                         L+ AM+DAL+ DR+DFVKLL+ENGVN+H FL + RLE  YN R        F     K  NL     +TL  +G ++E LMGG Y+  Y +K           L   K+ L +  M D        K +      E +I VD+   S F+YP+ EL+ W +L +R  MA+++   GEE++AK+L+A KL K M          + + ++L      F  L+  L D  YKH+     +LL YEL+ +S  T + LA   + + F+ H C+Q +L D+W G LR GK  GLKV++ +     IFP  P  L       L++F+T  +L+ Q
Sbjct:    1 MPTDSYGIIEFQGGGHINKAMYIRVSYDTKPDNLLHLMVKDWQLELPTLLISVHGGLQNFDLQPKLKQVFGKGLIKAAVTTGAWIFTGGVSTGVIRHVGDALKDHSSKSRGKVCAIGIAPWGIVENKEDLIGRDVTRPYQTMSNPLSKLSVLNNSHSHFILADNGTHGKYGAEVRLRRQLEKHISLQKI----NTRLGQG-VPLVCLILEGGPNVISIVLESLREDPPVPVVVCDGSGRASDIISFAHKYSEQDGLVNDSVRDQLLVTIQKTFNYNRNQAQQIYLMVMECMKKRELITVFRTASEGQQDIEMAILTALLKGT--NASAPDQLSLALAWNRVDIARSQIFVHGQHWPPAGSLPTSSTGQQDKPKSPIATRVSKGKPARGKKGKGAKSKPEPPEETDPRKLELLNWVNSLEQAMMDALVLDRVDFVKLLIENGVNIHHFLTIPRLEELYNTRLGPINTLHFVVRDVKKGNLPPDYQITLIDIGLVLEYLMGGAYRCNYTRKSFRTLYNNLYGLKRPKA-LKLLGMEDDDPRPKGKKKMKKKKEEEIDIDVDDPEVSRFQYPFHELMVWAVLMKRQKMALFLWQRGEEAMAKALVACKLYKAMAHESSRSELVDDISQDLDNNSKDFGQLAYELLDQSYKHDEHMAMKLLTYELKNWSNSTCLKLAVAAKHRDFIAHTCSQMLLTDMWMGCLRVGKSNGLKVILGI-----IFP--PAIL-------LLDFRTGDDLSYQ 725          

Query: 3187 QLSCRKKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYV-HIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEV-------YAAEIDPV--------DFPEESRLTPLAWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGN--VIKRTLQCMDQTQFQIGELHSRFNVMRV 4461
            +L   KKIY FF AP TKF+ N  ++++ ++L   +  +K  +ER    + +I + +IIT  L+  R+   +    + QK+ V  E  WN  D +     L+   +R                       N P     +GR +  +   +W I+ L++    +  G Y+ MI  M+  ++  V+I+ V++ +FGV RQ I++    +     + +NI+  PY+M+YGEV       YA EI+P         D  +     P AW  P  M  ++L A +++++L+IA   + + ++K  S +++ + RY +I+ +  RP  PPP II   IYI+LK++      C    K++          +   D R+H  GLKL LS +E++ L++FEE+ VE+Y++  +  DE +  N   I+ T Q ++    ++ E++ R + M+ 
Sbjct:  768 RLPVGKKIYYFFNAPYTKFWFNTTAYLVYLMLYNYIILVK--MERWPSLQEWIVISYIITLGLEKVRQILMSEPGKLKQKINVWLEEYWNITDLAAITTFLMGLLLRL---------------------QNEP--YMGYGRVIYCVDIIFWYIRVLDIFGVNKYLGPYVMMIGKMMIDMLYFVVIMLVVLMSFGVARQAILHPD--EEPTWRLARNIFYMPYWMIYGEVFADSIDLYAMEINPPCGENMYDEDGKKLPPCIPGAWLTPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQIWKFQRYQLIMTFHDRPVLPPPLIIFSHIYIVLKRL------CCRCRKKQ----------EGELDDRDH--GLKLTLSAEELKSLYEFEEQNVEEYFREKE--DEVQSSNDERIRITSQRVENMSMRLEEVNEREHTMKA 1163          

Query:  394 FPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYR-MEDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIF-----------------GIQTEWQSPV-----------------------------------------LDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLK-GDFSFNSMISKVCNLKKKQILTLRQVGSLIEILMGGGYQHQYCQK-----------LSPGKSLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVDNS--SNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXXXXXXXXXXXXXXXDNESEYL-EELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQ 2412
             PTD+YG +EFQGG H  KA Y+R+SY T P ++LHL++++W L +P L+IS+ GGL NFDLQPKLK+VF  GL+KAA TTG W+ T G+ TGV +HVG+ALK+        + A+GI+PWGIV++++ L+G++   PY +++N   K +VLN  H++F+LADNGT  K+GAE+ LRR LE++++ Q I    + RLG+  VP+V +++EGG     +V E + ++ PVPVVVC+GSGRA+D+++F H+YS+++G +   VR+Q+L T+Q+TF+    +A+ +Y  +  C+K+RELITV+R   +G  DI++AILTALL+ +    +  DQL+L +AWNR DIARSQIF                 G Q + +SP+                                         L+ AM+DAL+ DR+DFVKLL+ENGVN+H FL + RLE  YN R        F     K  NL     +TL  +G ++E LMGG Y+  Y +K           L   K+ L +  M D        K +      E +I VD+   S F+YP+ EL+ W +L +R  MA+++   GEE++AK+L+A KL K M          + + ++L      F  L+  L D  YKH+     +LL YEL+ +S  T + LA   + + F+ H C+Q +L D+W G LR GK  GLKV++ +     IFP  P  L       L++F+T  +L+ Q
Sbjct:    1 MPTDSYGIIEFQGGGHINKAMYIRVSYDTKPDNLLHLMVKDWQLELPTLLISVHGGLQNFDLQPKLKQVFGKGLIKAAVTTGAWIFTGGVSTGVIRHVGDALKDHSSKSRGKVCAIGIAPWGIVENKEDLIGRDVTRPYQTMSNPLSKLSVLNNSHSHFILADNGTHGKYGAEVRLRRQLEKHISLQKI----NTRLGQG-VPLVCLILEGGPNVISIVLESLREDPPVPVVVCDGSGRASDIISFAHKYSEQDGLVNDSVRDQLLVTIQKTFNYNRNQAQQIYLMVMECMKKRELITVFRTASEGQQDIEMAILTALLKGT--NASAPDQLSLALAWNRVDIARSQIFVHGQHWPPAGSLPTSSTGQQDKPKSPIATRVSKGKPARGKKGKGAKSKPEPPEETDPRKLELLNWVNSLEQAMMDALVLDRVDFVKLLIENGVNIHHFLTIPRLEELYNTRLGPINTLHFVVRDVKKGNLPPDYQITLIDIGLVLEYLMGGAYRCNYTRKSFRTLYNNLYGLKRPKA-LKLLGMEDDDPRPKGKKKMKKKKEEEIDIDVDDPEVSRFQYPFHELMVWAVLMKRQKMALFLWQRGEEAMAKALVACKLYKAMAHESSRSELVDDISQDLDNNSKDFGQLAYELLDQSYKHDEHMAMKLLTYELKNWSNSTCLKLAVAAKHRDFIAHTCSQMLLTDMWMGCLRVGKSNGLKVILGI-----IFP--PAIL-------LLDFRTGDDLSYQ 725          

Query: 3187 QLSCRKKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYV-HIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEV-------YAAEIDPV--------DFPEESRLTPLAWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGN--VIKRTLQCMDQTQFQIGELHSRFNVMRV 4461
            +L   KKIY FF AP TKF+ N  ++++ ++L   +  +K  +ER    + +I + +IIT  L+  R+   +    + QK+ V  E  WN  D +     L+   +R                       N P     +GR +  +   +W I+ L++    +  G Y+ MI  M+  ++  V+I+ V++ +FGV RQ I++    +     + +NI+  PY+M+YGEV       YA EI+P         D  +     P AW  P  M  ++L A +++++L+IA   + + ++K  S +++ + RY +I+ +  RP  PPP II   IYI+LK++      C    K++          +   D R+H  GLKL LS +E++ L++FEE+ VE+Y++  +  DE +  N   I+ T Q ++    ++ E++ R + M+ 
Sbjct:  768 RLPVGKKIYYFFNAPYTKFWFNTTAYLVYLMLYNYIILVK--MERWPSLQEWIVISYIITLGLEKVRQILMSEPGKLKQKINVWLEEYWNITDLAAITTFLMGLLLRL---------------------QNEP--YMGYGRVIYCVDIIFWYIRVLDIFGVNKYLGPYVMMIGKMMIDMLYFVVIMLVVLMSFGVARQAILHPD--EEPTWRLARNIFYMPYWMIYGEVFADSIDLYAMEINPPCGENMYDEDGKKLPPCIPGAWLTPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQIWKFQRYQLIMTFHDRPVLPPPLIIFSHIYIVLKRL------CCRCRKKQ----------EGELDDRDH--GLKLTLSAEELKSLYEFEEQNVEEYFREKE--DEVQSSNDERIRITSQRVENMSMRLEEVNEREHTMKA 1163          

Query:  394 FPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYR-MEDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIF-----------------GIQTEWQSPV-----------------------------------------LDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLK-GDFSFNSMISKVCNLKKKQILTLRQVGSLIEILMGGGYQHQYCQK-----------LSPGKSLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVDNS--SNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXXXXXXXXXXXXXXXDNESEYL-EELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQ 2412
             PTD+YG +EFQGG H  KA Y+R+SY T P ++LHL++++W L +P L+IS+ GGL NFDLQPKLK+VF  GL+KAA TTG W+ T G+ TGV +HVG+ALK+        + A+GI+PWGIV++++ L+G++   PY +++N   K +VLN  H++F+LADNGT  K+GAE+ LRR LE++++ Q I    + RLG+  VP+V +++EGG     +V E + ++ PVPVVVC+GSGRA+D+++F H+YS+++G +   VR+Q+L T+Q+TF+    +A+ +Y  +  C+K+RELITV+R   +G  DI++AILTALL+ +    +  DQL+L +AWNR DIARSQIF                 G Q + +SP+                                         L+ AM+DAL+ DR+DFVKLL+ENGVN+H FL + RLE  YN R        F     K  NL     +TL  +G ++E LMGG Y+  Y +K           L   K+ L +  M D        K +      E +I VD+   S F+YP+ EL+ W +L +R  MA+++   GEE++AK+L+A KL K M          + + ++L      F  L+  L D  YKH+     +LL YEL+ +S  T + LA   + + F+ H C+Q +L D+W G LR GK  GLKV++ +     IFP  P  L       L++F+T  +L+ Q
Sbjct:    1 MPTDSYGIIEFQGGGHINKAMYIRVSYDTKPDNLLHLMVKDWQLELPTLLISVHGGLQNFDLQPKLKQVFGKGLIKAAVTTGAWIFTGGVSTGVIRHVGDALKDHSSKSRGKVCAIGIAPWGIVENKEDLIGRDVTRPYQTMSNPLSKLSVLNNSHSHFILADNGTHGKYGAEVRLRRQLEKHISLQKI----NTRLGQG-VPLVCLILEGGPNVISIVLESLREDPPVPVVVCDGSGRASDIISFAHKYSEQDGLVNDSVRDQLLVTIQKTFNYNRNQAQQIYLMVMECMKKRELITVFRTASEGQQDIEMAILTALLKGT--NASAPDQLSLALAWNRVDIARSQIFVHGQHWPPAGSLPTSSTGQQDKPKSPIATRVSKGKPARGKKGKGAKSKPEPPEETDPRKLELLNWVNSLEQAMMDALVLDRVDFVKLLIENGVNIHHFLTIPRLEELYNTRLGPINTLHFVVRDVKKGNLPPDYQITLIDIGLVLEYLMGGAYRCNYTRKSFRTLYNNLYGLKRPKA-LKLLGMEDDDPRPKGKKKMKKKKEEEIDIDVDDPEVSRFQYPFHELMVWAVLMKRQKMALFLWQRGEEAMAKALVACKLYKAMAHESSRSELVDDISQDLDNNSKDFGQLAYELLDQSYKHDEHMAMKLLTYELKNWSNSTCLKLAVAAKHRDFIAHTCSQMLLTDMWMGCLRVGKSNGLKVILGI-----IFP--PAIL-------LLDFRTGDDLSYQ 725          

Query: 3187 QLSCRKKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYV-HIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEV-------YAAEIDPV--------DFPEESRLTPLAWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGN--VIKRTLQCMDQTQFQIGELHSRFNVMRV 4461
            +L   KKIY FF AP TKF+ N  ++++ ++L   +  +K  +ER    + +I + +IIT  L+  R+   +    + QK+ V  E  WN  D +     L+   +R                       N P     +GR +  +   +W I+ L++    +  G Y+ MI  M+  ++  V+I+ V++ +FGV RQ I++    +     + +NI+  PY+M+YGEV       YA EI+P         D  +     P AW  P  M  ++L A +++++L+IA   + + ++K  S +++ + RY +I+ +  RP  PPP II   IYI+LK++      C    K++          +   D R+H  GLKL LS +E++ L++FEE+ VE+Y++  +  DE +  N   I+ T Q ++    ++ E++ R + M+ 
Sbjct:  768 RLPVGKKIYYFFNAPYTKFWFNTTAYLVYLMLYNYIILVK--MERWPSLQEWIVISYIITLGLEKVRQILMSEPGKLKQKINVWLEEYWNITDLAAITTFLMGLLLRL---------------------QNEP--YMGYGRVIYCVDIIFWYIRVLDIFGVNKYLGPYVMMIGKMMIDMLYFVVIMLVVLMSFGVARQAILHPD--EEPTWRLARNIFYMPYWMIYGEVFADSIDLYAMEINPPCGENMYDEDGKKLPPCIPGAWLTPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQIWKFQRYQLIMTFHDRPVLPPPLIIFSHIYIVLKRL------CCRCRKKQ----------EGELDDRDH--GLKLTLSAEELKSLYEFEEQNVEEYFREKE--DEVQSSNDERIRITSQRVENMSMRLEEVNEREHTMKA 1163          

Query:  196 SLSTVSEKYNWIDDNILKLECNRFHP--KSNGYCACGRPAEEHIN-----------KNQFHNSSKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQI-----------LTLRQVGSLIEILMGGGYQHQYCQK---------LSPGK-SLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVD----NSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXX-XXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLE 2427
            S+  +  + +WI+    K EC    P  K    C CGR   +H+            KN+  + + I++E W+I  +T   PTDA+GT+EFQGG H  KA YVR+S+ T P  +LHL+ +EW L +P L+IS+ GGL NF+LQPKLK+VF  GL+KAA TTG W+ T G++TGV +HVG++LK+        I  +GI+PWGIV++++ L+GK+ + PY +++N   K  VLN  H++F+LADNGT  K+GAE+ LRR LE++++ Q I    + R+G+  VPVVA++VEGG     +V E + D  PVPVVVC+GSGRA+D+LAF H+YS+E G +   +R+Q+L T+Q+TF+    +A+ L+  +  C+K++ELITV+RM  +G  DID+AILTALL+ +    +  DQL+L +AWNR DIARSQIF    +W    L+ AM+DAL+ DR+DFVKLL+ENGV+MHRFL +SRLE  YN R        N++   V ++KK ++           ++L  +G +IE LMGG Y+  Y +K           P +   L +  M D +      K   +    E EI +D      ++F +P+ EL+ W +L +R  MA++    GEE++AK+L+A         +  + D   +  +EL     +F  L+V L D  YK + +   +LL YEL+ +S  T + LA   + + F+ H C+Q +L D+W G LR  K   LKV++ +L        LP ++L+L      EFK K E+    Q  E
Sbjct:   25 SVRLLKAQKSWIERAFHKRECVHIIPSTKDPHRCCCGRLIGQHVGLTPSISIIQNEKNEGRHRNDIQSEKWSIGKHTQLSPTDAFGTIEFQGGGHSNKAMYVRLSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDSLKDHASKSRGKICTIGIAPWGIVENQEDLVGKDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKI----NTRIGQG-VPVVALIVEGGPNVISIVLEYLRDNPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGA--NASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTR----HGPSNTLYHLVRDVKKVRVRHQGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPIRSGRK---TTKKREEEIDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSREFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSSLKVILGIL--------LPPSILSL------EFKNKDEMPYMSQANE 780          

Query: 3202 KKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYV-HIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPVDFP-------EESRLTPL------AWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGN--VIKRTLQCMDQTQFQIGELHSRFNVMRV 4461
            +KIYEF+ API KF+   ++++  ++L   +  +K  ++R    + +I + +I T  ++  R+   +    + QK KV  +  WN  D       ++ FS+      Q Q                       +GR +  +   YW I+ L++    +  G Y+ MI  M+  ++  V+I+ V++ +FGV RQ I++    +    N+ KNI+  PY+M+YGEV+A +IDP   P       E+ ++  L      AW VP  M  ++L A +++++L+IA   + + ++K  S +V+ + RY +I+ +  RP  PPP II     ++ K +      C  + KR+              D      GLKLF++ D+++K+HDFEE+C+E+Y++     D F   N   I+ T + ++    ++ E++ R + M+ 
Sbjct:  835 RKIYEFYNAPIVKFWFFTMAYMGYLMLFNYIVLVK--MDRWPSMQEWIVISYIFTLGIEKMREILMSEPGKLLQKFKVWLQEYWNLADL----VSILLFSIGMVLRLQEQPFSS-------------------YGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPS--EEPSWNLAKNIFYMPYWMIYGEVFADQIDP---PCGYNVTGEDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHFTMICKHL------CCRWRKRE-------------LDQDERDYGLKLFITEDDLKKVHDFEEQCIEEYFREKD--DRFNSSNDERIRVTAERVENMSMRLEEVNEREHFMKA 1219          

Query:  178 SLKSNRSLSTVSEKYNWIDDNILKLECNRFHP--KSNGYCACGRPAEEHIN-----------KNQFHNSSKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQI-----------LTLRQVGSLIEILMGGGYQHQYCQK---------LSPGKSLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVD----NSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXX-XXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLE 2427
            S K + +    + + +WI+    K EC    P  K    C CGR   +H+            KN+  + + I++E W+I  +T   PTDA+GT+EFQGG H  KA YVR+S+ T P  +LHL+ +EW L +P L+IS+ GGL NF+LQPKLK+VF  GL+KAA TTG W+ T G++TGV +HVG++LK+        I  +GI+PWGIV++++ L+GK+ + PY +++N   K  VLN  H++F+LADNGT  K+GAE+ LRR LE++++ Q I    + R+G+  VPVVA++VEGG     +V E + D  PVPVVVC+GSGRA+D+LAF H+YS+E G +   +R+Q+L T+Q+TF+    +A+ L+  +  C+K++ELITV+RM  +G  DID+AILTALL+ +    +  DQL+L +AWNR DIARSQIF    +W    L+ AM+DAL+ DR+DFVKLL+ENGV+MHRFL +SRLE  YN R        N++   V ++KK ++           ++L  +G +IE LMGG Y+  Y +K           P +  +P+     T                E EI +D      ++F +P+ EL+ W +L +R  MA++    GEE++AK+L+A         +  + D   +  +EL     +F  L+V L D  YK + +   +LL YEL+ +S  T + LA   + + F+ H C+Q +L D+W G LR  K   LKV++ +L        LP ++L+L      EFK K E+    Q  E
Sbjct:   48 STKRSGAAQQPTAQKSWIERAFHKRECVHIIPSTKDPHRCCCGRLIGQHVGLTPSISIIQNEKNEGRHRNDIQSEKWSIGKHTQLSPTDAFGTIEFQGGGHSNKAMYVRLSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDSLKDHASKSRGKICTIGIAPWGIVENQEDLVGKDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKI----NTRIGQG-VPVVALIVEGGPNVISIVLEYLRDNPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGA--NASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTR----HGPSNTLYHLVRDVKKVRVRHQGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPIRSGRKTTKK------------REEEIDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSREFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSSLKVILGIL--------LPPSILSL------EFKNKDEMPYMSQANE 799          

Query: 3202 KKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYV-HIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPVD----FPEESRLTPL------AWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGN--VIKRTLQCMDQTQFQIGELHSRFNVMRV 4461
            +KIYEF+ API KF+   ++++  ++L   +  +K  ++R    + +I + +I T  ++  R+   +    + QK KV  +  WN  D       ++ FS+      Q Q                       +GR +  +   YW I+ L++    +  G Y+ MI  M+  ++  V+I+ V++ +FGV RQ I++    +    N+ KNI+  PY+M+YGEV+A +IDP        E+ ++  L      AW VP  M  ++L A +++++L+IA   + + ++K  S +V+ + RY +I+ +  RP  PPP II     ++ K +      C  + KR+              D      GLKLF++ D+++K+HDFEE+C+E+Y++     D F   N   I+ T + ++    ++ E++ R + M+ 
Sbjct:  854 RKIYEFYNAPIVKFWFFTMAYMGYLMLFNYIVLVK--MDRWPSMQEWIVISYIFTLGIEKMREILMSEPGKLLQKFKVWLQEYWNLADL----VSILLFSIGMVLRLQEQPFSS-------------------YGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPS--EEPSWNLAKNIFYMPYWMIYGEVFADQIDPPCGYNVTGEDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHFTMICKHL------CCRWRKRE-------------LDQDERDYGLKLFITEDDLKKVHDFEEQCIEEYFREKD--DRFNSSNDERIRVTAERVENMSMRLEEVNEREHFMKA 1238          

Query:  196 SLSTVSEKYNWIDDNILKLECNRFHP--KSNGYCACGRPAEEHIN-----------KNQFHNSSKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQI-----------LTLRQVGSLIEILMGGGYQHQYCQK---------LSPGK-SLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVD----NSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXX-XXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLE 2427
            S+  +  + +WI+    K EC    P  K    C CGR   +H+            KN+  + + I++E W+I  +T   PTDA+GT+EFQGG H  KA YVR+S+ T P  +LHL+ +EW L +P L+IS+ GGL NF+LQPKLK+VF  GL+KAA TTG W+ T G++TGV +HVG++LK+        I  +GI+PWGIV++++ L+GK+ + PY +++N   K  VLN  H++F+LADNGT  K+GAE+ LRR LE++++ Q I    + R+G+  VPVVA++VEGG     +V E + D  PVPVVVC+GSGRA+D+LAF H+YS+E G +   +R+Q+L T+Q+TF+    +A+ L+  +  C+K++ELITV+RM  +G  DID+AILTALL+ +    +  DQL+L +AWNR DIARSQIF    +W    L+ AM+DAL+ DR+DFVKLL+ENGV+MHRFL +SRLE  YN R        N++   V ++KK ++           ++L  +G +IE LMGG Y+  Y +K           P +   L +  M D +      K   +    E EI +D      ++F +P+ EL+ W +L +R  MA++    GEE++AK+L+A         +  + D   +  +EL     +F  L+V L D  YK + +   +LL YEL+ +S  T + LA   + + F+ H C+Q +L D+W G LR  K   LKV++ +L        LP ++L+L      EFK K E+    Q  E
Sbjct:   31 SVRLLKAQKSWIERAFHKRECVHIIPSTKDPHRCCCGRLIGQHVGLTPSISIIQNEKNEGRHRNDIQSEKWSIGKHTQLSPTDAFGTIEFQGGGHSNKAMYVRLSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDSLKDHASKSRGKICTIGIAPWGIVENQEDLVGKDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKI----NTRIGQG-VPVVALIVEGGPNVISIVLEYLRDNPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGA--NASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTR----HGPSNTLYHLVRDVKKVRVRHQGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPIRSGRK---TTKKREEEIDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSREFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSSLKVILGIL--------LPPSILSL------EFKNKDEMPYMSQANE 786          

Query: 3202 KKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYV-HIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPVD----FPEESRLTPL------AWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGN--VIKRTLQCMDQTQFQIGELHSRFNVMRV 4461
            +KIYEF+ API KF+   ++++  ++L   +  +K  ++R    + +I + +I T  ++  R+   +    + QK KV  +  WN  D       ++ FS+      Q Q                       +GR +  +   YW I+ L++    +  G Y+ MI  M+  ++  V+I+ V++ +FGV RQ I++    +    N+ KNI+  PY+M+YGEV+A +IDP        E+ ++  L      AW VP  M  ++L A +++++L+IA   + + ++K  S +V+ + RY +I+ +  RP  PPP II     ++ K +      C  + KR+              D      GLKLF++ D+++K+HDFEE+C+E+Y++     D F   N   I+ T + ++    ++ E++ R + M+ 
Sbjct:  841 RKIYEFYNAPIVKFWFFTMAYMGYLMLFNYIVLVK--MDRWPSMQEWIVISYIFTLGIEKMREILMSEPGKLLQKFKVWLQEYWNLADL----VSILLFSIGMVLRLQEQPFSS-------------------YGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPS--EEPSWNLAKNIFYMPYWMIYGEVFADQIDPPCGYNVTGEDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHFTMICKHL------CCRWRKRE-------------LDQDERDYGLKLFITEDDLKKVHDFEEQCIEEYFREKD--DRFNSSNDERIRVTAERVENMSMRLEEVNEREHFMKA 1225          

Query:  196 SLSTVSEKYNWIDDNILKLECNRFHP--KSNGYCACGRPAEEHIN-----------KNQFHNSSKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQI-----------LTLRQVGSLIEILMGGGYQHQYCQK---------LSPGK-SLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVD----NSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXX-XXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLE 2427
            S+  +  + +WI+    K EC    P  K    C CGR   +H+            KN+  + + I++E W+I  +T   PTDA+GT+EFQGG H  KA YVR+S+ T P  +LHL+ +EW L +P L+IS+ GGL NF+LQPKLK+VF  GL+KAA TTG W+ T G++TGV +HVG++LK+        I  +GI+PWGIV++++ L+GK+ + PY +++N   K  VLN  H++F+LADNGT  K+GAE+ LRR LE++++ Q I    + R+G+  VPVVA++VEGG     +V E + D  PVPVVVC+GSGRA+D+LAF H+YS+E G +   +R+Q+L T+Q+TF+    +A+ L+  +  C+K++ELITV+RM  +G  DID+AILTALL+ +    +  DQL+L +AWNR DIARSQIF    +W    L+ AM+DAL+ DR+DFVKLL+ENGV+MHRFL +SRLE  YN R        N++   V ++KK ++           ++L  +G +IE LMGG Y+  Y +K           P +   L +  M D +      K   +    E EI +D      ++F +P+ EL+ W +L +R  MA++    GEE++AK+L+A         +  + D   +  +EL     +F  L+V L D  YK + +   +LL YEL+ +S  T + LA   + + F+ H C+Q +L D+W G LR  K   LKV++ +L        LP ++L+L      EFK K E+    Q  E
Sbjct:   25 SVRLLKAQKSWIERAFHKRECVHIIPSTKDPHRCCCGRLIGQHVGLTPSISIIQNEKNEGRHRNDIQSEKWSIGKHTQLSPTDAFGTIEFQGGGHSNKAMYVRLSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDSLKDHASKSRGKICTIGIAPWGIVENQEDLVGKDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKI----NTRIGQG-VPVVALIVEGGPNVISIVLEYLRDNPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGA--NASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTR----HGPSNTLYHLVRDVKKVRVRHQGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPIRSGRK---TTKKREEEIDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSREFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSSLKVILGIL--------LPPSILSL------EFKNKDEMPYMSQANE 780          

Query: 3202 KKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYV-HIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPVD----FPEESRLTPL------AWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGN--VIKRTLQCMDQTQFQIGELHSRFNVMRV 4461
            +KIYEF+ API KF+   ++++  ++L   +  +K  ++R    + +I + +I T  ++  R+   +    + QK KV  +  WN  D       ++ FS+      Q Q                       +GR +  +   YW I+ L++    +  G Y+ MI  M+  ++  V+I+ V++ +FGV RQ I++    +    N+ KNI+  PY+M+YGEV+A +IDP        E+ ++  L      AW VP  M  ++L A +++++L+IA   + + ++K  S +V+ + RY +I+ +  RP  PPP II     ++ K +      C  + KR+              D      GLKLF++ D+++K+HDFEE+C+E+Y++     D F   N   I+ T + ++    ++ E++ R + M+ 
Sbjct:  835 RKIYEFYNAPIVKFWFFTMAYMGYLMLFNYIVLVK--MDRWPSMQEWIVISYIFTLGIEKMREILMSEPGKLLQKFKVWLQEYWNLADL----VSILLFSIGMVLRLQEQPFSS-------------------YGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPS--EEPSWNLAKNIFYMPYWMIYGEVFADQIDPPCGYNVTGEDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHFTMICKHL------CCRWRKRE-------------LDQDERDYGLKLFITEDDLKKVHDFEEQCIEEYFREKD--DRFNSSNDERIRVTAERVENMSMRLEEVNEREHFMKA 1219          

Query:  178 SLKSNRSLSTVSEKYNWIDDNILKLECNRFHP--KSNGYCACGRPAEEHIN-----------KNQFHNSSKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQI-----------LTLRQVGSLIEILMGGGYQHQYCQK---------LSPGK-SLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVD----NSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXX-XXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLE 2427
            S K + +    + + +WI+    K EC    P  K    C CGR   +H+            KN+  + + I++E W+I  +T   PTDA+GT+EFQGG H  KA YVR+S+ T P  +LHL+ +EW L +P L+IS+ GGL NF+LQPKLK+VF  GL+KAA TTG W+ T G++TGV +HVG++LK+        I  +GI+PWGIV++++ L+GK+ + PY +++N   K  VLN  H++F+LADNGT  K+GAE+ LRR LE++++ Q I    + R+G+  VPVVA++VEGG     +V E + D  PVPVVVC+GSGRA+D+LAF H+YS+E G +   +R+Q+L T+Q+TF+    +A+ L+  +  C+K++ELITV+RM  +G  DID+AILTALL+ +    +  DQL+L +AWNR DIARSQIF    +W    L+ AM+DAL+ DR+DFVKLL+ENGV+MHRFL +SRLE  YN R        N++   V ++KK ++           ++L  +G +IE LMGG Y+  Y +K           P +   L +  M D +      K   +    E EI +D      ++F +P+ EL+ W +L +R  MA++    GEE++AK+L+A         +  + D   +  +EL     +F  L+V L D  YK + +   +LL YEL+ +S  T + LA   + + F+ H C+Q +L D+W G LR  K   LKV++ +L        LP ++L+L      EFK K E+    Q  E
Sbjct:   48 STKRSGAAQQPTAQKSWIERAFHKRECVHIIPSTKDPHRCCCGRLIGQHVGLTPSISIIQNEKNEGRHRNDIQSEKWSIGKHTQLSPTDAFGTIEFQGGGHSNKAMYVRLSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDSLKDHASKSRGKICTIGIAPWGIVENQEDLVGKDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKI----NTRIGQG-VPVVALIVEGGPNVISIVLEYLRDNPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGA--NASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTR----HGPSNTLYHLVRDVKKVRVRHQGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPIRSGRK---TTKKREEEIDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSREFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSSLKVILGIL--------LPPSILSL------EFKNKDEMPYMSQANE 809          

Query: 3202 KKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYV-HIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPVD----FPEESRLTPL------AWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGN--VIKRTLQCMDQTQFQIGELHSRFNVMRV 4461
            +KIYEF+ API KF+   ++++  ++L   +  +K  ++R    + +I + +I T  ++  R+   +    + QK KV  +  WN  D       ++ FS+      Q Q                       +GR +  +   YW I+ L++    +  G Y+ MI  M+  ++  V+I+ V++ +FGV RQ I++    +    N+ KNI+  PY+M+YGEV+A +IDP        E+ ++  L      AW VP  M  ++L A +++++L+IA   + + ++K  S +V+ + RY +I+ +  RP  PPP II     ++ K +      C  + KR+              D      GLKLF++ D+++K+HDFEE+C+E+Y++     D F   N   I+ T + ++    ++ E++ R + M+ 
Sbjct:  864 RKIYEFYNAPIVKFWFFTMAYMGYLMLFNYIVLVK--MDRWPSMQEWIVISYIFTLGIEKMREILMSEPGKLLQKFKVWLQEYWNLADL----VSILLFSIGMVLRLQEQPFSS-------------------YGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPS--EEPSWNLAKNIFYMPYWMIYGEVFADQIDPPCGYNVTGEDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHFTMICKHL------CCRWRKRE-------------LDQDERDYGLKLFITEDDLKKVHDFEEQCIEEYFREKD--DRFNSSNDERIRVTAERVENMSMRLEEVNEREHFMKA 1248          

Query:  196 SLSTVSEKYNWIDDNILKLECNRFHP--KSNGYCACGRPAEEHIN-----------KNQFHNS-SKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIR-------------CLKGDFSFNSMISKVCNLKKKQILTLRQVGSLIEILMGGGYQHQYCQK---------LSPGKSLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVD----NSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXX-XXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKV 2298
            S+  +  + +WI+    K EC    P  K    C CGR   +H+            KN+   S + I++E W+I  +T   PTDA+GT+EFQGG H  KA YVR+S+ T P  +LHL+ +EW L +P L+IS+ GGL NF+LQPKLK+VF  GL+KAA TTG W+ T G++TGV +HVG+ALK+        I  +GI+PWGIV++++ L+G++ + PY +++N   K  VLN  H++F+LADNGT  K+GAE+ LRR LE++++ Q I    + R+G+  VPVVA++VEGG     +V E + D  PVPVVVC+GSGRA+D+LAF H+YS+E G +   +R+Q+L T+Q+TF+    +A+ L+  +  C+K++ELITV+RM  +G  DID+AILTALL+ +    +  DQL+L +AWNR DIARSQIF    +W    L+ AM+DAL+ DR+DFVKLL+ENGV+MHRFL +SRLE  YN R               K ++     I    NL     ++L  +G +IE LMGG Y+  Y +K           P +  +P+             +   +    E E+ +D      ++F +P+ EL+ W +L +R  MA++    GEE++AK+L+A         +  + D   +  +EL      F  L+V L D  YK + +   +LL YEL+ +S  T + LA   + + F+ H C+Q +L D+W G LR  K  GLK+
Sbjct:   54 SVRLLKAQKSWIERAFYKRECVHIIPSTKDPHRCCCGRLIGQHVGLTPSISVLQNEKNESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKI----NTRIGQG-VPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGA--NASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKREYPGFGWIYFKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLR------------RGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKL 777          

Query:  196 SLSTVSEKYNWIDDNILKLECNRFHP--KSNGYCACGRPAEEHIN-----------KNQFHNS-SKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQI-----------------LTLRQVGSLIEILMGGGYQHQYCQK---------LSPGK-SLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVD----NSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXX-XXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEYLN 2439
            S+  +  + +WI+    K EC    P  K    C CGR   +H+            KN+   S + I++E W+I  +T   PTDA+GT+EFQGG H  KA YVR+S+ T P  +LHL+ +EW L +P L+IS+ GGL NF+LQPKLK+VF  GL+KAA TTG W+ T G++TGV +HVG+ALK+        I  +GI+PWGIV++++ L+G++ + PY +++N   K  VLN  H++F+LADNGT  K+GAE+ LRR LE++++ Q I    + R+G+  VPVVA++VEGG     +V E + D  PVPVVVC+GSGRA+D+LAF H+YS+E G +   +R+Q+L T+Q+TF+    +A+ L+  +  C+K++ELITV+RM  +G  DID+AILTALL+ +    +  DQL+L +AWNR DIARSQIF    +W    L+ AM+DAL+ DR+DFVKLL+ENGV+MHRFL +SRLE  YN R        N++   V ++KK++                  ++L  +G +IE LMGG Y+  Y +K           P +   L +  M D +      K   +    E E+ +D      ++F +P+ EL+ W +L +R  MA++    GEE++AK+L+A         +  + D   +  +EL      F  L+V L D  YK + +   +LL YEL+ +S  T + LA   + + F+ H C+Q +L D+W G LR  K  GLKV++ +L        LP ++L+L      EFK K ++    Q  E +L 
Sbjct:   54 SVRLLKAQKSWIERAFYKRECVHIIPSTKDPHRCCCGRLIGQHVGLTPSISVLQNEKNESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKI----NTRIGQG-VPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGA--NASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTR----HGPSNTLYHLVRDVKKREYPGFGWIYFKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPLRRGRK---TTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGIL--------LPPSILSL------EFKNKDDMPYMTQAQEIHLQ 820          

Query: 3202 KKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYV-HIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPVDFPEESR-------LTPL---AWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGN--VIKRTLQCMDQTQFQIGELHSRFNVMRV 4461
            +KIYEF+ API KF+   +++I  ++L   +  +K  +ER    + +I + +I T  ++  R+   +    + QK+KV  +  WN  D       ++ FSV      Q Q  +                     GR +  +   YW I+ L++    +  G Y+ MI  M+  ++  V+I+ V++ +FGV RQ I++    +     + KNI+  PY+M+YGEV+A +IDP     E+R       L P    AW VP  M  ++L A +++++L+IA   + + ++K  S +V+ + RY +I+ +  RP  PPP II   +      M F    C +   RK+         +++ D R++  GLKLF++ DE++K+HDFEE+C+E+Y++     D F   N   I+ T + ++    ++ E++ R + M+ 
Sbjct:  872 RKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVK--MERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDL----IAILLFSVGMILRLQDQPFRSD-------------------GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPN--EEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKTIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHM-----TMIFQHVCCRW---RKH---------ESDQDERDY--GLKLFITDDELKKVHDFEEQCIEEYFREKD--DRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKA 1256          

Query:  196 SLSTVSEKYNWIDDNILKLECNRFHP--KSNGYCACGRPAEEHIN-----------KNQFHNS-SKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQI-----LTLRQVGSLIEILMGGGYQHQYCQK---------LSPGKSLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVD----NSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXX-XXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEYLN 2439
            S+  +  + +WI+    K EC    P  K    C CGR   +H+            KN+   S + I++E W+I  +T   PTDA+GT+EFQGG H  KA YVR+S+ T P  +LHL+ +EW L +P L+IS+ GGL NF+LQPKLK+VF  GL+KAA TTG W+ T G++TGV +HVG+ALK+        I  +GI+PWGIV++++ L+G++ + PY +++N   K  VLN  H++F+LADNGT  K+GAE+ LRR LE++++ Q I    + R+G+  VPVVA++VEGG     +V E + D  PVPVVVC+GSGRA+D+LAF H+YS+E G +   +R+Q+L T+Q+TF+    +A+ L+  +  C+K++ELITV+RM  +G  DID+AILTALL+ +    +  DQL+L +AWNR DIARSQIF    +W    L+ AM+DAL+ DR+DFVKLL+ENGV+MHRFL +SRLE  YN R        N++   V ++KK  +     ++L  +G +IE LMGG Y+  Y +K           P +  +P+             +   +    E E+ +D      ++F +P+ EL+ W +L +R  MA++    GEE++AK+L+A         +  + D   +  +EL      F  L+V L D  YK + +   +LL YEL+ +S  T + LA   + + F+ H C+Q +L D+W G LR  K  GLKV++ +L        LP ++L+L      EFK K ++    Q  E +L 
Sbjct:   54 SVRLLKAQKSWIERAFYKRECVHIIPSTKDPHRCCCGRLIGQHVGLTPSISVLQNEKNESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKI----NTRIGQG-VPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGA--NASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTR----HGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLR------------RGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGIL--------LPPSILSL------EFKNKDDMPYMTQAQEIHLQ 798          

Query: 3202 KKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYV-HIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPVDFPEESR-------LTPL---AWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGN--VIKRTLQCMDQTQFQIGELHSRFNVMRV 4461
            +KIYEF+ API KF+   +++I  ++L   +  +K  +ER    + +I + +I T  ++  R+   +    + QK+KV  +  WN  D       ++ FSV      Q Q  +                     GR +  +   YW I+ L++    +  G Y+ MI  M+  ++  V+I+ V++ +FGV RQ I++    +     + KNI+  PY+M+YGEV+A +IDP     E+R       L P    AW VP  M  ++L A +++++L+IA   + + ++K  S +V+ + RY +I+ +  RP  PPP II   +      M F    C +   RK+         +++ D R++  GLKLF++ DE++K+HDFEE+C+E+Y++     D F   N   I+ T + ++    ++ E++ R + M+ 
Sbjct:  850 RKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVK--MERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDL----IAILLFSVGMILRLQDQPFRSD-------------------GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPN--EEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKTIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHM-----TMIFQHVCCRW---RKH---------ESDQDERDY--GLKLFITDDELKKVHDFEEQCIEEYFREKD--DRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKA 1234          

Query:  223 NWIDDNILKLECNRFHP--KSNGYCACGRPAEEHIN-----------KNQFHNS-SKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQI-----LTLRQVGSLIEILMGGGYQHQYCQK---------LSPGKSLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVD----NSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXX-XXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEYLN 2439
            +WI+    K EC    P  K    C CGR   +H+            KN+   S + I++E W+I  +T   PTDA+GT+EFQGG H  KA YVR+S+ T P  +LHL+ +EW L +P L+IS+ GGL NF+LQPKLK+VF  GL+KAA TTG W+ T G++TGV +HVG+ALK+        I  +GI+PWGIV++++ L+G++ + PY +++N   K  VLN  H++F+LADNGT  K+GAE+ LRR LE++++ Q I    + R+G+  VPVVA++VEGG     +V E + D  PVPVVVC+GSGRA+D+LAF H+YS+E G +   +R+Q+L T+Q+TF+    +A+ L+  +  C+K++ELITV+RM  +G  DID+AILTALL+ +    +  DQL+L +AWNR DIARSQIF    +W    L+ AM+DAL+ DR+DFVKLL+ENGV+MHRFL +SRLE  YN R        N++   V ++KK  +     ++L  +G +IE LMGG Y+  Y +K           P +  +P+             +   +    E E+ +D      ++F +P+ EL+ W +L +R  MA++    GEE++AK+L+A         +  + D   +  +EL      F  L+V L D  YK + +   +LL YEL+ +S  T + LA   + + F+ H C+Q +L D+W G LR  K  GLKV++ +L        LP ++L+L      EFK K ++    Q  E +L 
Sbjct:   65 SWIERAFYKRECVHIIPSTKDPHRCCCGRLIGQHVGLTPSISVLQNEKNESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKI----NTRIGQG-VPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGA--NASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTR----HGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLR------------RGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGIL--------LPPSILSL------EFKNKDDMPYMTQAQEIHLQ 800          

Query: 3202 KKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYV-HIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPVDFPEESR-------LTPL---AWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGN--VIKRTLQCMDQTQFQIGELHSRFNVMRV 4461
            +KIYEF+ API KF+   +++I  ++L   +  +K  +ER    + +I + +I T  ++  R+   +    + QK+KV  +  WN  D       ++ FSV      Q Q  +                     GR +  +   YW I+ L++    +  G Y+ MI  M+  ++  V+I+ V++ +FGV RQ I++    +     + KNI+  PY+M+YGEV+A +IDP     E+R       L P    AW VP  M  ++L A +++++L+IA   + + ++K  S +V+ + RY +I+ +  RP  PPP II   +      M F    C +   RK+         +++ D R++  GLKLF++ DE++K+HDFEE+C+E+Y++     D F   N   I+ T + ++    ++ E++ R + M+ 
Sbjct:  852 RKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVK--MERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDL----IAILLFSVGMILRLQDQPFRSD-------------------GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPN--EEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKTIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHM-----TMIFQHVCCRW---RKH---------ESDQDERDY--GLKLFITDDELKKVHDFEEQCIEEYFREKD--DRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKA 1236          

Query:  223 NWIDDNILKLECNRFHP--KSNGYCACGRPAEEHIN-----------KNQFHNS-SKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQI-----LTLRQVGSLIEILMGGGYQHQYCQK---------LSPGK-SLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVD----NSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXX-XXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEYLN 2439
            +WI+    K EC    P  K    C CGR   +H+            KN+   S + I++E W+I  +T   PTDA+GT+EFQGG H  KA YVR+S+ T P  +LHL+ +EW L +P L+IS+ GGL NF+LQPKLK+VF  GL+KAA TTG W+ T G++TGV +HVG+ALK+        I  +GI+PWGIV++++ L+G++ + PY +++N   K  VLN  H++F+LADNGT  K+GAE+ LRR LE++++ Q I    + R+G+  VPVVA++VEGG     +V E + D  PVPVVVC+GSGRA+D+LAF H+YS+E G +   +R+Q+L T+Q+TF+    +A+ L+  +  C+K++ELITV+RM  +G  DID+AILTALL+ +    +  DQL+L +AWNR DIARSQIF    +W    L+ AM+DAL+ DR+DFVKLL+ENGV+MHRFL +SRLE  YN R        N++   V ++KK  +     ++L  +G +IE LMGG Y+  Y +K           P +   L +  M D +      K   +    E E+ +D      ++F +P+ EL+ W +L +R  MA++    GEE++AK+L+A         +  + D   +  +EL      F  L+V L D  YK + +   +LL YEL+ +S  T + LA   + + F+ H C+Q +L D+W G LR  K  GLKV++ +L        LP ++L+L      EFK K ++    Q  E +L 
Sbjct:   65 SWIERAFYKRECVHIIPSTKDPHRCCCGRLIGQHVGLTPSISVLQNEKNESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKI----NTRIGQG-VPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGA--NASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTR----HGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPLRRGRK---TTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGIL--------LPPSILSL------EFKNKDDMPYMTQAQEIHLQ 810          

Query: 3202 KKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYV-HIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPVDFPEESR-------LTPL---AWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGN--VIKRTLQCMDQTQFQIGELHSRFNVMRV 4461
            +KIYEF+ API KF+   +++I  ++L   +  +K  +ER    + +I + +I T  ++  R+   +    + QK+KV  +  WN  D       ++ FSV      Q Q  +                     GR +  +   YW I+ L++    +  G Y+ MI  M+  ++  V+I+ V++ +FGV RQ I++    +     + KNI+  PY+M+YGEV+A +IDP     E+R       L P    AW VP  M  ++L A +++++L+IA   + + ++K  S +V+ + RY +I+ +  RP  PPP II   +      M F    C +   RK+         +++ D R++  GLKLF++ DE++K+HDFEE+C+E+Y++     D F   N   I+ T + ++    ++ E++ R + M+ 
Sbjct:  862 RKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVK--MERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDL----IAILLFSVGMILRLQDQPFRSD-------------------GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPN--EEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKTIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHM-----TMIFQHVCCRW---RKH---------ESDQDERDY--GLKLFITDDELKKVHDFEEQCIEEYFREKD--DRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKA 1246          

Query:  223 NWIDDNILKLECNRF--HPKSNGYCACGRPAEEHINKNQFHNSSKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELP--PDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM----EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQILTLRQVGSLIEILMGGGYQHQYC-QKLSP--GKSLLPVTDMCDTLSSVDNFKNLYSNSLN--------ENEIGVDNSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXXXXXXXXXXXXXXXDN-ESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEYL 2436
            +WI+ N  K EC +F   PK +  C CG+    H       + S    + W    +T P PTDAYGT+EFQGG HPTKA+YVR+S+ T P  ++ L  +EWNL +P L+I++ GG ANFDLQ KLKK    GL+KAAKTTG W+ T G +TGVTK VG+AL  E   +   +V++GI+PWGIV+    LLG  +  P +SI++   K AVLN  H YFLL DNGT  K+GAE++LRR LE++++   +    H     S  PVV +++EGG    R V E VTD  PVPVVVC+GSGRAADLLAF+H+Y+ +  E P    +R+ ++ T+Q+TF +   ++E LY+E+  C + + LITV+R+    E    ++D  ILTAL +     L+  +QL+L + WNR DIARS+IF    EW +  LD AM+ AL +DR+DFVKLLLENGV+M +FL + RLE  YN +    +     +     ++ K  I TL  +G +I  LMGG Y+  Y  +K  P   K +    + C   S+    +   +NSL+         +E+ +     F +P+ ELL W +LT+R  MA+ M   GEE++AKSL++ KL K M      D+ ++E  EEL+ +  +FE     L D  Y+ + E+ +RLL  EL  +S  + +SLA     +  L H C+Q IL DLW GGLR  K    KV++ L        A+P  +      R ++FK+K+EL   PQT EE+L
Sbjct:  116 SWIETNFQKRECIKFIPCPKDDTKCCCGQAQITHQTIPGIESGSP--GDLWLPTKHTRPQPTDAYGTIEFQGGAHPTKAQYVRLSFDTRPELLVQLFTKEWNLELPKLLITVQGGKANFDLQAKLKKEIRKGLLKAAKTTGAWIFTGGTNTGVTKQVGDALLLEGQQRTGRVVSIGIAPWGIVERNHELLGHNREVPCHSISSPRSKLAVLNNRHAYFLLVDNGTQAKYGAELILRRKLEKFISNLKLHPFTH-----SSTPVVCLVIEGGTNTIRAVLEYVTDSPPVPVVVCDGSGRAADLLAFVHKYASDGEEQPVLESMRDYLIGTIQKTFEVGLDQSEKLYQELLQCTRNKNLITVFRIQEKPEGEAQELDQTILTALFKSQ--HLSPPEQLSLALTWNRVDIARSEIFVYGQEWPNGALDEAMMQALEHDRIDFVKLLLENGVSMKKFLTIPRLEELYNTKHGPANTLGYILRDVRPHIPKGYIYTLHDIGLVINKLMGGAYRSYYTRRKFRPIYAKVMNSYANACRKSSTYQYQRYAGANSLSLVTGLLPFTSEMAL-----FEFPFNELLIWAVLTKRQQMALLMWTHGEEALAKSLVSCKLYKAMAHEAAEDDLDTEIYEELRSYAKEFESKGNKLLDFSYRQDAEKAQRLLTCELHSWSNQSCLSLAVAANHRALLAHPCSQVILADLWMGGLRTRKNTNFKVILGL--------AMPFYI------RQLDFKSKEELQQMPQTEEEHL 845          

Query: 3190 LSCRKKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYVHIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPV--DFPEESRLTPLAWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGNVIKRTLQCMDQTQFQIGELHSRFNV 4452
            L  +KK YEF+ APITKF+ + I+++  +I+      +K   +   + E Y   +I T   +  R+  ++  + I  K  V   ++WN  D +     +I  + R+                       N  +I   GR +  + S YW ++ L ++   +  G  + M+  M+K ++  V++L+V++ +FGV RQ I+Y         +++K +  +PYFMLYGEV+A +IDP   + P +       W  P+ M +++L A +++++L+IA   +I+ ++   S +V+M+ R+ ++++Y+ +P  PPPFI L   Y LLK       +C    K            DN         GLKLFL  D++E+L+DFEEECVE ++   +          +K T + ++    +I +++ + N+
Sbjct:  911 LRLKKKFYEFYTAPITKFWADSIAYMFFLIMFSFTVLVKME-QMPRWQEWYSIAYITTLGFEKVREIISSEPVAITHKFSVWAWNMWNPCDGAAIILFVIGLAFRF---------------------RENTMDI---GRVIYCVDSIYWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLAVVLMSFGVSRQAILYPN--KQPTWSLIKEVTFQPYFMLYGEVFAGDIDPPCGEDPSQPGCVTGHWVTPITMSMYLLIANILLINLLIAVFNNIFNEVNSVSHQVWMFQRFTVVMEYQQKPVLPPPFIALCHFYSLLK-------YCVRKAKGLEVQR------DN---------GLKLFLEKDDLERLYDFEEECVEGFFHEQEIILNQSTDERVKNTTERVETMSQKIEDINQKENI 1284          

Query:  196 SLSTVSEKYNWIDDNILKLECNRFHP--KSNGYCACGRPAEEHIN-----------KNQFHNS-SKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMR---------------------NHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQI-----LTLRQVGSLIEILMGGGYQHQYCQK---------LSPGK-SLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVD----NSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXX-XXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEYLN 2439
            S+  +  + +WI+    K EC    P  K    C CGR   +H+            KN+   S + I++E W+I  +T   PTDA+GT+EFQGG H  KA YVR+S+ T P  +LHL+ +EW L +P L+IS+ GGL NF+LQPKLK+VF  GL+KAA TTG W+ T G++TGV +HVG+ALK+        I  +GI+PWGIV++++ L+G++ + PY +++N   K  VLN  H++F+LADNGT  K+GAE+ LRR LE++++ Q I  R                     +   +G+  VPVVA++VEGG     +V E + D  PVPVVVC+GSGRA+D+LAF H+YS+E G +   +R+Q+L T+Q+TF+    +A+ L+  +  C+K++ELITV+RM  +G  DID+AILTALL+ +    +  DQL+L +AWNR DIARSQIF    +W    L+ AM+DAL+ DR+DFVKLL+ENGV+MHRFL +SRLE  YN R        N++   V ++KK  +     ++L  +G +IE LMGG Y+  Y +K           P +   L +  M D +      K   +    E E+ +D      ++F +P+ EL+ W +L +R  MA++    GEE++AK+L+A         +  + D   +  +EL      F  L+V L D  YK + +   +LL YEL+ +S  T + LA   + + F+ H C+Q +L D+W G LR  K  GLKV++ +L        LP ++L+L      EFK K ++    Q  E +L 
Sbjct:   54 SVRLLKAQKSWIERAFYKRECVHIIPSTKDPHRCCCGRLIGQHVGLTPSISVLQNEKNESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRCLPFFSLDSRLFYSFWGSCQLDSVGIGQG-VPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGA--NASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTR----HGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPLRRGRK---TTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGIL--------LPPSILSL------EFKNKDDMPYMSQAQEIHLQ 833          

Query: 3202 KKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYV-HIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPVDFPEESR-------LTPL---AWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGN--VIKRTLQCMDQTQFQIGELHSRFNVMRV 4461
            +KIYEF+ API KF+   +++I  ++L   +  +K  +ER    + +I + +I T  ++  R+   +    + QK+KV  +  WN  D       ++ FSV      Q Q  +                     GR +  +   YW I+ L++    +  G Y+ MI  M+  ++  V+I+ V++ +FGV RQ I++    +     + KNI+  PY+M+YGEV+A +IDP     E+R       L P    AW VP  M  ++L A +++++L+IA   + + ++K  S +V+ + RY +I+ +  RP  PPP II   + ++ + +      C  + K    H + P       D R++  GLKLF++ DE++K+HDFEE+C+E+Y++     D F   N   I+ T + ++    ++ E++ R + M+ 
Sbjct:  885 RKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVK--MERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDL----IAILLFSVGMILRLQDQPFRSD-------------------GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPN--EEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHL------CCRWRK----HESDP-------DERDY--GLKLFITDDELKKVHDFEEQCIEEYFREKD--DRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKA 1269          

Query:  178 SLKSNRSLSTVSEKYNWIDDNILKLECNRFHP--KSNGYCACGRPAEEHI---------NKNQFHNSSKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQ-----SPVLD------------------------------------------------NAMIDALIN----DRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKV--CNLKKKQILTLRQVGSLIEILMGGGYQHQYCQK---------LSPGK-SLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVDNS--SNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXXXXXXXXXXXXXXXDNESEYLEELK--LWGNK--FEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQ 2412
            S+KS+ S S   +K  WI+    K EC    P  K    C CG+   +HI            +    +  ++  W++  +T  +PTD+YG LEFQGG +  KA Y+R+SY T P  +LHL++++W L +P L+IS+ GGL +F++QPKLK+VF  GL+KAA TTG W+ T G+ TGV  HVG+ALK+        + A+GI+PWG+V++++ L+GK+    Y +++N   K +VLN  H +F+LADNGT+ K+GAE+ LRR LE++++ Q I    + RLG+  VPVV ++VEGG     +V E + ++ PVPVVVC+GSGRA+D+L+F H+Y DE G +   +R+Q+L T+Q+TF+    ++  L+  +  C+K++EL+TV+RM  +G  D+++AILTALL+ +    +  DQL+L +AWNR DIARSQIF     W      +P +D                                                NA+  A+++    DR+DFVKLL+ENGVNM  FL + RLE  YN R L    + + ++  V   NL     ++L  +G ++E LMGG Y+  Y +K           P +   L +  M D        K        E +I VD+   S F+YP+ EL+ W +L +R  MA+++   GEE +A    A+   K  K +    +ESE ++++   L  N   F  L+V L D  YKH+ +   +LL YEL+ +S  T + LA   + + F+ H C+Q +L D+W G LR  K  GLKV++ +L        +P T+L       +EF+T  + + Q
Sbjct:   15 SIKSSTSGSQKGQK-AWIEKTFCKRECIFVIPSTKDPNRCCCGQLTNQHIPPLPSGAPSTTGEDTKQADTQSGKWSVSKHTQSYPTDSYGILEFQGGGYSNKAMYIRVSYDTKPDSLLHLMVKDWQLELPKLLISVHGGLQSFEMQPKLKQVFGKGLIKAAMTTGAWIFTGGVSTGVVSHVGDALKDHSSKSRGRLCAIGIAPWGMVENKEDLIGKDVTRVYQTMSNPLSKLSVLNNSHTHFILADNGTLGKYGAEVKLRRQLEKHISLQKI----NTRLGQG-VPVVGLVVEGGPNVVSIVLEYLKEDPPVPVVVCDGSGRASDILSFAHKYCDEGGVINESLRDQLLVTIQKTFNYSKSQSYQLFAIIMECMKKKELVTVFRMGSEGQQDVEMAILTALLKGT--NASAPDQLSLALAWNRVDIARSQIFVFGPHWPPLGSLAPPVDTKATEKEKKPPTATTKGRGKGKGKKKGKVKEEVEEETDPRKLELLNWVNALEQAMLDALVLDRVDFVKLLIENGVNMQHFLTIPRLEELYNTR-LGPPNTLHLLVRDVKKSNLPPDYHISLIDIGLVLEYLMGGAYRCNYTRKSFRTLYNNLFGPKRPKALKLLGMEDDEPPAKGKKKKKKKKEEEIDIDVDDPAVSRFQYPFHELMVWAVLMKRQKMAVFLWQRGEECMA---KALVACKLYKAMAHESSESELVDDISQDLDNNSKDFGQLAVELLDQSYKHDEQVAMKLLTYELKNWSNSTCLKLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNPGLKVIMGIL--------IPPTIL------FLEFRTYDDFSYQ 820          

Query: 3205 KIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYV------------------HIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEID----PVDFP--------EESRLTPL---AWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGNVIKRTLQCMDQTQFQIGELHSRFNVMRV 4461
            KI EF+ API KF+                    +++  + Y  L+ YV                  +I++  L+  R+   +    ++QK+KV  +  WN  D       L+A S+  F      +++ Q                  +GR +  +    W I+ L++    +  G Y+ MI  M+  ++  V+I+ V++ +FGV RQ I++    +     + +NI+  PY+M+YGEV+A +ID     ++ P        E  RL P    AW  P  M  ++L A +++++L+IA   + + ++K  S +V+ + RY +I+ +  RP  PPP      + IL       M+      K++              D      GLKLFLS +E++KLH+FEE+CV+++++  +   +      I+ T + ++    ++ E++ R N M+ 
Sbjct:  864 KICEFYNAPIVKFWF-------------------YTISYLGYLLLFNYVILVRMDGWPSPQEWIVISYIVSLALEKIREILMSEPGKLSQKIKVWLQEYWNITD-------LVAISM--FMVGAILRLQSQP--------------YMGYGRVIYCVDIILWYIRVLDIFGVNKYLGPYVMMIGKMMIDMLYFVVIMLVVLMSFGVARQAILHPE--EKPSWKLARNIFYMPYWMIYGEVFADQIDLYAMEINPPCGENLYDEEGKRLPPCIPGAWLTPALMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHDRPVLPPP------MIILSHIYIIIMRLSGRCRKKR------------EGDQEERDRGLKLFLSDEELKKLHEFEEQCVQEHFREKEDEQQSSSDERIRVTSERVENMSMRLEEINERENFMKT 1253          

Query:  178 SLKSNRSLSTVSEKYNWIDDNILKLECNRFHP--KSNGYCACGRPAEEHI---------NKNQFHNSSKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQ-----SPVLD------------------------------------------------NAMIDALIN----DRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKV--CNLKKKQILTLRQVGSLIEILMGGGYQHQYCQK---------LSPGK-SLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVDNS--SNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXXXXXXXXXXXXXXXDNESEYLEELK--LWGNK--FEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQ 2412
            S+KS+ S S   +K  WI+    K EC    P  K    C CG+   +HI         +  +       ++  W++  +T  +PTD+YG LEFQGG +  KA Y+R+SY T P  +LHL++++W L +P L+IS+ GGL +F++QPKLK+VF  GL+KAA TTG W+ T G+ TGV  HVG+ALK+        + A+GI+PWG+V++++ L+GK+    Y +++N   K +VLN  H +F+LADNGT+ K+GAE+ LRR LE++++ Q I    + RLG+  VPVV ++VEGG     +V E + ++ PVPVVVC+GSGRA+D+L+F H+Y DE G +   +R+Q+L T+Q+TF+    ++  L+  +  C+K++EL+TV+RM  +G  D+++AILTALL+ +   ++  DQL+L +AWNR DIARSQIF     W      +P +D                                                NA+  A+++    DR+DFVKLL+ENGVNM  FL + RLE  YN R L    + + ++  V   NL     ++L  +G ++E LMGG Y+  Y +K           P +   L +  M D        K        E +I VD+   S F+YP+ EL+ W +L +R  MA+++   GEE +A    A+   K  K +    +ESE ++++   L  N   F  L+V L D  YKH+ +   +LL YEL+ +S  T + LA   + + F+ H C+Q +L D+W G LR  K  GLKV++ +L        +P T+L       +EF++  + + Q
Sbjct:   15 SIKSSTSGSQKGQK-AWIEKTFCKRECIFVIPSTKDPNRCCCGQLTNQHIPPLPSVTPSSTAEDTKQGDAQSGKWSVSKHTQSYPTDSYGILEFQGGGYSNKAMYIRVSYDTKPDSLLHLMVKDWQLELPKLLISVHGGLQSFEMQPKLKQVFGKGLIKAAMTTGAWIFTGGVSTGVVSHVGDALKDHSSKSRGRLCAIGIAPWGMVENKEDLVGKDVTRVYQTMSNPLSKLSVLNNSHTHFILADNGTLGKYGAEVKLRRQLEKHISLQKI----NTRLGQG-VPVVGLVVEGGPNVVSIVLEYLREDPPVPVVVCDGSGRASDILSFAHKYCDEGGVINESLRDQLLVTIQKTFNYSKSQSHQLFAIIMECMKKKELVTVFRMGSEGQQDVEMAILTALLKGT--NVSAPDQLSLALAWNRVDIARSQIFVFGPHWPPLGSLAPPVDTKVAEKEKKPPTATTKGRGKGKGKKKGKVKEEVEEETDPRKIELLNWVNALEQAMLDALVLDRVDFVKLLIENGVNMQHFLTIPRLEELYNTR-LGPPNTLHLLVRDVKKSNLPPDYHISLIDIGLVLEYLMGGAYRCNYTRKSFRTLYNNLFGPKRPKALKLLGMEDDEPPAKGKKKKKKKKEEEIDIDVDDPAVSRFQYPFHELMVWAVLMKRQKMAVFLWQRGEECMA---KALVACKLYKAMAHESSESELVDDISQDLDNNSKDFGQLAVELLDQSYKHDEQVAMKLLTYELKNWSNSTCLKLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNPGLKVIMGIL--------IPPTIL------FLEFRSYDDFSYQ 820          

Query: 3205 KIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYV------------------HIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEID----------PVDFP--------EESRLTPL---AWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGNVIKRTLQCMDQTQFQIGELHSRFNVMRV 4461
            KI EF+ API KF+                    +++  + Y  L+ YV                  +I++  L+  R+   +    ++QK+KV  +  WN  D       L+A S+  F      ++++Q                  +GR +  +    W I+ L++    +  G Y+ MI  M+  ++  V+I+ V++ +FGV RQ I++    +     + +NI+  PY+M+YGEV+A +ID           ++ P        E  RL P    AW  P  M  ++L A +++++L+IA   + + ++K  S +V+ + RY +I+ +  RP  PPP IIL  IYI++      M+      K++              D      GLKLFLS +E++KLH+FEE+CV+++++  +   +      I+ T + ++    ++ E++ R N M+ 
Sbjct:  864 KICEFYNAPIVKFWF-------------------YTISYLGYLLLFNYVILVRMDGWPSPQEWIVISYIVSLALEKIREILMSEPGKLSQKIKVWLQEYWNITD-------LVAISM--FMVGAILRLQNQP--------------YMGYGRVIYCVDIILWYIRVLDIFGVNKYLGPYVMMIGKMMIDMLYFVVIMLVVLMSFGVARQAILHPE--EKPSWKLARNIFYMPYWMIYGEVFADQIDRKTRIHIYAMEINPPCGENLYDEEGKRLPPCIPGAWLTPALMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHDRPVLPPPMIILSHIYIIV------MRLSGRCRKKR------------EGDQEERDRGLKLFLSDEELKKLHEFEEQCVQEHFREKEDEQQSSSDERIRVTSERVENMSMRLEEINERENFMKA 1259          

Query:  223 NWIDDNILKLECNRFHPKSNG---------------YCACGRPAEEH--INKNQFHNSSKIK--------NEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKV--CNLKKKQILTLRQVGSLIEILMG-------------------GGYQHQYCQKLSPG-----KSLLPVTDMCDT---------LSSVDNFKNLYSNSLNENE--------IGVDNSSNFRYPY--TELLQWTILTRRYDMAMYMVMSGEESIAXXXXX-XXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGL--REGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEY 2433
            +WI+  + K EC    P S                  C CGR  ++H     +     S +K         E W++  +T   PTDAYG + FQGG H  +A+YVR+SY T P  +L LLL+EW + +P LVIS+ GG+  F+L P++K++   GL+KAA TTG W++T G++TGV KHVG+ALK         I  +GI+PWG++++R  L+G++ + PY ++ N   K  VLN  H++F+L D+GTV K+GAE+ LRR LE+ +  Q    R H R+G+  VPVVA++ EGG      V E + +  PVPVVVCEG+GRAADLLA++H+ ++E G LP      ++ T+++TF+    EA  L++ M  C+K++ELITV+ +  +   DIDVAILTALL+ +    +  DQL LT+AW+R DIA++ +F    +W    L+ AM+DAL+ DR+ FVKLL+ENGV+MH+FL + RLE  YN +    +     +I  V   NL     +TL  +G +IE LMG                   GG   +  +  S       KS     +  D          + +   ++     S+ E +        + +D+    R+PY   ELL W  L +R  MA ++   GEES+AK+L+A         +    D   +  EELK + N F  L+V L +  ++ +     +LL YEL+ +S  T + LA   + +PF+ H CTQ +L+D+W G L  R+  W       V+LSI+     +P  +L      ++E+KTK E++  PQ+ + +
Sbjct:    5 SWIESTLTKRECVYIIPSSKDPHRCLPGCQICQQLVRCFCGRLVKQHACFTASLAMKYSDVKLGEHFNQAIEEWSVEKHTEQSPTDAYGVINFQGGSHSYRAKYVRLSYDTKPEIILQLLLKEWQMELPKLVISVHGGMQKFELHPRIKQLLGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKEHASRSSRKICTIGIAPWGVIENRNDLVGRDVVAPYQTLLNPLSKLNVLNNLHSHFILVDDGTVGKYGAEVRLRRELEKTINQQ----RIHARIGQG-VPVVALIFEGGPNVILTVLEYLQESPPVPVVVCEGTGRAADLLAYIHKQTEEGGNLPDAAEPDIISTIKKTFNFGQSEAVHLFQTMMECMKKKELITVFHIGSEDHQDIDVAILTALLKGT--NASAFDQLILTLAWDRVDIAKNHVFVYGQQWLVGSLEQAMLDALVMDRVSFVKLLIENGVSMHKFLTIPRLEELYNTKQGPTNPMLFHLIRDVKQGNLPPGYKITLIDIGLVIEYLMGGTYRCTYTRKRFRLIYNSLGGNNRRSGRNTSSSTPQLRKSHETFGNRADKKEKMRHNHFIKTAQPYRPKMDASMEEGKKKRTKDEIVDIDDPETKRFPYPLNELLIWACLMKRQVMARFLWQHGEESMAKALVACKIYRSMAYEAKQSDLVDDTSEELKQYSNDFGQLAVELLEQSFRQDETMAMKLLTYELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMGRLNMRKNSWYK-----VILSIL-----VPPAIL------MLEYKTKAEMSHIPQSQDAH 792          

Query: 3187 QLSCRKKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYV-HIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPV--DFPEESRLTPLAWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGN--VIKRTLQCMDQTQFQIGELHSRFNVMR 4458
            +L   +K Y F++API KF+ N ++++  ++L   +  +K  +E++   + +I + +I T  ++  R+   +    I+QK+KV F   +N  D        + F +R+ A + +             +N+ + + +F+ GR +  L   +W ++ L+ +   +  G Y+ MI  M+  +   V+I+++++ +FGV R+ I+Y    +    ++ K+I   PY+M++GEVYA EID    D    +   P  W  P    +++    +++++L+IA   ++Y ++K  S  V+ Y RY  I+ Y  +P  PPP IIL  I  L         FC    +RK          D   D      G KLFL+ ++ +KLHDFEE+CVE Y+      D+F  G+   I+ T + ++Q   QI E+  R N ++
Sbjct:  838 KLPITRKFYAFYHAPIVKFWFNTLAYLGFLMLYTFVVLVK--MEQLPSVQEWIVIAYIFTYAIEKVREVFMSEAGKISQKIKVWFSDYFNVSDTIAIISFFVGFGLRFGAKWNY-------------INAYD-NHVFVAGRLIYCLNIIFWYVRLLDFLAVNQQAGPYVMMIGKMVANMFYIVVIMALVLLSFGVPRKAILYPH--EEPSWSLAKDIVFHPYWMIFGEVYAYEIDVCANDSTLPTICGPGTWLTPFLQAVYLFVQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQRYHFIMAYHEKPVLPPPLIILSHIVSL---------FCCVCKRRK---------KDKTSD------GPKLFLTEEDQKKLHDFEEQCVEMYFDEKD--DKFNSGSEERIRVTFERVEQMSIQIKEVGDRVNYIK 1222          

Query:  226 WIDDNILKLECNRF----HPKSNGYCACGRPAEEHINKNQFHNSSK-------------------IKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIA-NKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRMEDGCPD-IDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQILTLRQVGSLIEILMGGGYQHQYCQKLSPG------------------------------------------------KSLLPVTDMCDTLSSVDNFKNLYSNSL---------NENEIGVDNSSN--------FRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXX-XXXXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALP-ITLLTLKSNRLIEFKTKQELALQPQTLEEYLN 2439
            WI+ NI+ LEC +F    H KSN  C+CG    EH +  Q    ++                     NE W++  +T   PT+AYGT+EFQGGPHPTKARYVR+   T P  VLHLLL EW +RVPNLVISI+GGLAN  LQ KL++V   G+++AAKTTG W+VT GLD GVT+H+GEALK+E+HI+G+NIVALGI+PWG VQHR+ L+G +  C YYS      +++A LN  HNYFLLADNGT  KFG E+ LRR LE+YLA QPI MR +G   KSRVP+V VL+EGG Q FR VFELVT   PVP+VVC+GSGRAADLLAFMHRY++E+G+L   +R+Q++  + R F +   EAE LY E+KLC+KRR LI+V+RM +G  D ID+ ILTALLQ S   LT A+QL+LTMAWNRPDIARS++F     W    L+NAM DAL+NDRL+FV+LLL  G+ + RFL   RLE  YN+     + SF+ + +KV  L  KQ +TLR VG LIE L+GGGYQH YC K S                                                  KS+LP T    ++S++   K L +  +         ++  +    SSN        FRYPYTELLQWT+LTRR DMA ++V++GEESIAK+L     L       LD + + E L E +      E L+V LQDHCY+H+ ++ KRLL YELQ FS +T +SLAY+C+SK F+GH CTQ ILNDLWYGGLR+G  VG KV ++L+ +I + P  P I     K ++ +EFKTK+ELA QPQTL+E+L+
Sbjct:   43 WIEQNIVCLECAKFVFARHSKSNPCCSCGLTFSEHPSNVQIEALTQQNLNLQPDISNTGDYHLKPTNNEHWHVKTHTQEIPTNAYGTVEFQGGPHPTKARYVRLHCETCPEVVLHLLLHEWKIRVPNLVISIVGGLANAPLQAKLQQVVQHGILRAAKTTGAWIVTNGLDIGVTRHIGEALKDEVHIRGSNIVALGIAPWGYVQHRETLIGLDNTCSYYSQGWRPGRQEAPLNPDHNYFLLADNGTSGKFGGELGLRRRLEQYLAQQPIDMRRYGG-SKSRVPIVGVLLEGGTQTFRTVFELVTGRNPVPIVVCDGSGRAADLLAFMHRYANEDGDLSTQLRDQMVANISRAFQIRRFEAEGLYSELKLCMKRRHLISVFRMGEGDSDEIDITILTALLQVSGQNLTPAEQLSLTMAWNRPDIARSKVFAKFNNWSKTTLENAMADALLNDRLEFVQLLLTKGLRIQRFLTRERLEELYNVDV--NNQSFHKLFAKV--LGTKQKITLRSVGQLIENLVGGGYQHSYCSKPSTADLMGSPNHGNGWLPNVNVTFINKHGSTVSEPVDSKTIRSGNILNNTSDKSILPCTLNPGSISNLITSKELVTQHITNIINRQHTSQQHVPYSASSNDINQSNRYFRYPYTELLQWTLLTRRLDMAKFLVLAGEESIAKALFSVKLLRSIRHVTLDEETDIELLNECRSHELALERLAVDLQDHCYRHDQDQAKRLLTYELQAFSKNTCLSLAYMCESKVFIGHPCTQAILNDLWYGGLRKGDLVGAKVALILIGLI-VPPLYPLIAFFFTKKSKFLEFKTKEELAQQPQTLQEHLD 866          

Query: 3010 VSPTVSSFSFHQPLNILQPTLTDMSHRA-SVTFNNLSFTKCAPDALFEFCQENPQISPGTQLSCRKKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYVHIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPVDFPEESRLTPLAWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHN----NKPGMND----------------------------NNFDHRNH------------------SAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGNVIKRTLQCMDQTQFQIGELHSRFNVMR 4458
            ++P++ +++ H   N L  TL D S  + S    N  +  C     ++F   N     G QLS RKK+YEFF AP+      V+   L I             +   + ELY+Y+HI+T +LD FR+     G    QK  VH  + WN +D       +I   +RY+                  +N N     ++WG+NL+I+  + W ++ LELMQ WR  G Y+ M+  M++ ++P + +L + + AFG +RQGIMY     +++   +K I LKPYFMLYGEVYA EIDP+D+P ES+  P    VP+A V+++L ++++ ++++IA   DI+ ++++ S  VY YLRY +II+YESRP  PPPFII+ WIY+ ++ +Y   K      KR+ +      N P ++D                            +  D RN                   SAGLKLFL+ DE+EKLHDFEEECVEDY +  +  +  +    ++   + +DQ QF++ E+H R   +R
Sbjct: 1261 INPSIFTYNHHNKQNKLNSTLKDHSFSSLSYHHRNGQWVPCDLTVGYDFQSTNNH---GLQLSWRKKVYEFFSAPLLYLVFLVLFIGLCIHT--------LPPDTFSFLELYVYLHILTYWLDKFREVTLNPGATYIQKFAVHLSAFWNSYDMIMCLLSIIGIILRYYGI----------------INQN----YYMWGKNLLIICCSLWQMRFLELMQIWRFSGPYIYMLVKMVRLMIPMLTLLFLPLLAFGTIRQGIMYPKHTYVNL-EAVKGIMLKPYFMLYGEVYAGEIDPIDWPIESQTAPFLEIVPIATVIYLLYSIILFVNVVIAVFNDIFARVRQQSELVYNYLRYAVIIEYESRPLLPPPFIIISWIYMSIRNIYRIRK------KRRASIQPNTLNLPNLSDAQKQTSQNGNNTNNNNNNNNNNNDPNSPSKSDSRNRRDNNEPQDTVIDSATTELSAGLKLFLNPDEVEKLHDFEEECVEDYTRVTRKAELHKAEGQVEILNKKIDQLQFRMDEIHVRQRHLR 1756          

Query:  226 WIDDNILKLECNRF----HPKSNGYCACGRPAEEHINKNQFHNSSK-------------------IKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRMEDGCPD-IDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQILTLRQVGSLIEILMGGGYQHQYCQKLSPGKSLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVDNSSN--------FRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXXXXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALP-ITLLTLKSNRLIEFKTKQELALQPQTLEEYLN 2439
            WI+ NI+ LEC +F    H KSN  C+CG    EH +  Q    ++                     NE W++  +T   PT+AYGT+EFQGGPHPTKARYVR+   T P  VLHLLL EW +RVPNLVISI+GGLAN  LQ KL++V   G+++AAKTTG W+VT GLD GVT+H+GEALK+E+HI+G+NIVALGI+PWG VQHR+ L+G + +C Y    +  +++A LN  HNYFLLADNGT  KFG E+ LRR LE+YLA QPI MR +G   KSRVP+V VL+EGG Q FR VFELVT   PVP+VVC+GSGRAADLLAFMHRY++E+G+L   +R+Q++  + R F +   EAE LY E+KLC+KRR LI+V+RM +G  D ID+ ILTALLQ     LT A+QL+LTMAWNRPDIARS++F     W    L+NAM DAL+NDRL+FV+LLL  G+ + RFL   RLE  YN+     + SF+ + +KV  L  KQ +TLR VG LIE L+GGGYQH YC K S    L+   +  +    + N  N    S  +  +    SSN        FRYPYTELLQWT+LTRR DMA ++V++GEESIAK+ + + ++                    L+    E L+V LQDHCY+H+ ++ KRLL YELQ FS +T +SLAY+C+SK F+GH CTQ ILNDLWYGGLR+G  VG KV ++L+ +I + P  P I     K ++ +EFKTK+ELA QPQTL+E+L+
Sbjct:   43 WIEQNIVCLECAKFVFARHSKSNPCCSCGLTFSEHPSNVQIEALTQQNLNLQPDISNTGDYHLKPTNNEHWHVKTHTQEIPTNAYGTVEFQGGPHPTKARYVRLHCETCPEVVLHLLLHEWKIRVPNLVISIVGGLANAPLQAKLQQVVQHGILRAAKTTGAWIVTNGLDIGVTRHIGEALKDEVHIRGSNIVALGIAPWGYVQHRETLIGLD-VCVY----SPGRQEAPLNPDHNYFLLADNGTSGKFGGELGLRRRLEQYLAQQPIDMRRYGG-SKSRVPIVGVLLEGGTQTFRTVFELVTGRNPVPIVVCDGSGRAADLLAFMHRYANEDGDLSTQLRDQMVANISRAFQIRRFEAEGLYSELKLCMKRRHLISVFRMGEGDSDEIDITILTALLQGQ--NLTPAEQLSLTMAWNRPDIARSKVFAKFNNWSKTTLENAMADALLNDRLEFVQLLLTKGLRIQRFLTRERLEELYNVDV--NNQSFHKLFAKV--LGTKQKITLRSVGQLIENLVGGGYQHSYCSKPSTA-DLMGSPNHGNVTQHITNIINRQHTS--QQHVPYSASSNDINQSNRYFRYPYTELLQWTLLTRRLDMAKFLVLAGEESIAKASVLISIIV-----------------FFLYIYALERLAVDLQDHCYRHDQDQAKRLLTYELQAFSKNTCLSLAYMCESKVFIGHPCTQAILNDLWYGGLRKGDLVGAKVALILIGLI-VPPLYPLIAFFFTKKSKFLEFKTKEELAQQPQTLQEHLD 780          

Query: 3010 VSPTVSSFSFHQPLNILQPTLTDMSHRA-SVTFNNLSFTKCAPDALFEFCQENPQISPGTQLSCRKKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYVHIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPVDFPEESRLTPLAWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGNVIKRTLQCMDQTQFQIGELHSRFNVMR 4458
            ++P++ +++ H   N L  TL D S  + S    N  +  C     ++F   N   + G QLS RKK+YEFF AP+T+FYL+V+ +++ ++L I L       +   + ELY+Y+HI+T +LD FR+     G    QK  VH  + WN +D       +I   +RY+                  +N N     ++WG+NL+I+  + W ++ LELMQ WR  G Y+ M+  M++ ++P + +L + + AFG +RQGIMY     +++  + K I LKPYFMLYGEVYA EIDP+D+P ES+  P    VP+A V+++L ++++ ++++IA   DI+ ++++ S  VY YLRY +II+YESRP  PPPFII+ WIY+ ++ +Y   +   Y   +  +   KP +  ++F  R  +   +LFL+ DE+EKLHDFEEECVEDY +  +  +  +    ++   + +DQ QF++ E+H R   +R
Sbjct: 1031 INPSIFTYNHHNKQNKLNSTLKDHSFSSLSYHHRNGQWVPCDLTVGYDFQSTN---NHGLQLSWRKKVYEFFSAPVTRFYLHVLLYLVFLVLFIGLCIHTLPPDTFSFLELYVYLHILTYWLDKFREVTLNPGATYIQKFAVHLSAFWNSYDMIMCLLSIIGIILRYYGI----------------INQN----YYMWGKNLLIICCSLWQMRFLELMQIWRFSGPYIYMLVKMVRLMIPMLTLLFLPLLAFGTIRQGIMYPKHTYVNLEAV-KGIMLKPYFMLYGEVYAGEIDPIDWPIESQTAPFLEIVPIATVIYLLYSIILFVNVVIAVFNDIFARVRQQSELVYNYLRYAVIIEYESRPLLPPPFIIISWIYMSIRNIY---RLVMYIDIKATSL--KPCL--SHFVTR--TIEEELFLNPDEVEKLHDFEEECVEDYTRVTRKAELHKAEGQVEILNKKIDQLQFRMDEIHVRQRHLR 1481          

Query:  226 WIDDNILKLECNRFHPKS----NGYCACGRPAEEHINKNQFHNSSKI-------------------KNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQ-AVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRMEDGCPD-IDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQILTLRQVGSLIEILMGGGYQHQYCQKLSPGK----SLLPVTDMCDTLSSVDNFKNL------------------YSNSLNENEIGV-------------------------DNSSN---FRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXX-XXXXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVL--IVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEYLN 2439
            WI++NI  LEC ++ P      N  C CG   + H    +    +++                   + E W++  +T   PT+AYGT+EFQGGPHPT+ARYVR+ Y T+P  ++HLLL EW +RVPNLVIS++GGLAN  LQ KL++V   GL++AAKTTG WV+T GLD GVT+H+GEAL +E+HI+G+NIVALGI+PWG VQHR+ L+G    C YYS   +   Q A L+ HHNYFLLADNGT  KFG E+ LRR LE+YLA QPI MR HG   KSR+P+V VL+EGG Q FR VFELVT  YPVPVVVC+GSGRAADLLAFMHRY++E+G+LP  ++EQ++ T+ RTF L   E+E LY E++LC+KRR LI+++RM +G  D ID+ ILTALLQ S  KLT A+QL+LTMAW+RPDIARS++F   + W +  L+NAM DAL+NDRL+FVKLLL  G+ + RFL V RLE  Y       + SF+ + +K+  +  +Q +TLR VG LIE L+GGGYQH YC K   G+       P +    + SS  +   L                  Y+N  +  E G                          D SS    FRYPYTELLQW +LTRRY MA +MV++GEESIAK+L     L       +  ++E E  +E +   + FE L+  LQDHCY+H+P++ KRLL YEL+ FS +T +SLA++C+SK F+GH CTQ+ILNDLWYGGLR GK VG KV   ++ + +  ++P +   L T   ++ +EFKTK+ELA QPQTL+EYL+
Sbjct:   41 WIEENITMLECAKYIPSRRSMVNSRCYCGLSVKNHAPNVRLDAVTQLGAECFRSLLLKNGSRRTAPQTERWHVKTHTREMPTNAYGTVEFQGGPHPTRARYVRLHYDTSPETLMHLLLHEWRIRVPNLVISMLGGLANAPLQNKLQRVVQSGLLRAAKTTGAWVITNGLDIGVTRHIGEALGDEVHIRGSNIVALGIAPWGYVQHRETLIGLNHTCAYYSQGWRPGCQDAPLDPHHNYFLLADNGTTGKFGGELCLRRRLEQYLAQQPIDMRRHGG-SKSRIPIVGVLLEGGQQTFRTVFELVTGRYPVPVVVCDGSGRAADLLAFMHRYANEDGDLPAPLKEQIISTISRTFQLHRHESEGLYSELRLCMKRRHLISIFRMGEGDSDEIDITILTALLQVSGHKLTPAEQLSLTMAWDRPDIARSKVFTSCSTWSTSTLENAMADALLNDRLEFVKLLLAKGLGIQRFLTVGRLEELYIAASDVNNQSFHKLFAKI--MGARQRITLRAVGQLIENLIGGGYQHCYCDKSGFGRLPSFEHRPASADVGSYSSDPHLAGLVHRLMTDRKFPFPRKSVTYANIDHAVEHGGLKFPASLGHMVTGHKQHSTSVLNTEDASSRDCIFRYPYTELLQWALLTRRYKMARFMVLAGEESIAKALFSVKLLRGIRHASVHEESEVEVAKEFRTQEDLFERLAFDLQDHCYRHDPDQAKRLLIYELRAFSNNTCLSLAHMCESKVFIGHKCTQSILNDLWYGGLRNGKMVGAKVALLLMGMLLPPVYPIIGYCLST--RSKFLEFKTKEELAQQPQTLQEYLD 851          

Query: 3100 TFNNLSFTKCAPDALFEFCQENPQISPGTQLSCRKKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYVHIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPVDFPEESRLTPLAWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKF--CFYFFKR-----KYTHNN----KP-------------GMNDNN-------FDHRNHSA-GLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGNVIKRTLQCMDQTQFQIGELHSRFNVMR 4458
            T +N   T   PD L      +       QLS RK+IYEFF AP+T+FYL+VI +++ ++L I L           + E+Y+Y+HI+T FLD FR+     G N  QKM+VH  + WN +D       +I   +RY                           I++WG+NL+I+  A W ++  ELMQ WR  G  +  + +MI+ ++P + ++ + + AFG +R+GIMY     + + ++ K   LKPYFM+YGEVYA EIDP D+P ES  TPL   VP+A V+F+L +++V +S++IA   DI+ +M++ S  VY YLRY +II+YESRP  PPPFII+ WIY+LL  +Y   K        ++     + T +N    KP             G ND+        F   N +A GLKLFL   E+EKLHDFEEECV+DYW+ ++  +  +         Q +D  QF+I E+H   N +R
Sbjct: 1255 TLHNFQLTPGTPDRLEGLFTSDTS----HQLSWRKRIYEFFSAPVTRFYLHVILYLVFLVLYIGLCLHTIPARSWSFLEIYVYLHIVTYFLDKFREVTLVRGSNYLQKMRVHLGAFWNTYDLVMCSVSMIGIGLRYLGMIYL--------------------PIYMWGKNLLIVCCAMWQMRFFELMQIWRFSGPIIYTVFMMIRVMIPMLSLVFLPLLAFGTMREGIMYPNRTHVDLDSV-KGTMLKPYFMIYGEVYADEIDPNDWPPESINTPLKEAVPIATVIFLLYSIIVFISVVIATFNDIFSRMRQQSELVYNYLRYAVIIEYESRPLLPPPFIIISWIYMLLLHVYRVRKSRRALAALEKLSSDGRSTEDNSNTPKPKRRTKGDIIEFSKGHNDSRPPPSPGVFSTSNETAMGLKLFLDSAEVEKLHDFEEECVDDYWRESRKLESLDAERRTDVLNQKLDHLQFRISEIHIHQNQLR 1714          

Query:  226 WIDDNILKLECNRFHPKS----NGYCACGRPAEEHINKNQFHNSSKI-------------------KNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQ-AVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRMEDGCPD-IDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQILTLRQVGSLIEILMGGGYQHQYCQKLSPGKSLLPVTD------------------------MCDTLSSVDNFKNLYSNSLNENEIGV-------------------------DNSSN---FRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXX-XXXXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVL--IVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEYLN 2439
            WI++NI  LEC ++ P      N  C CG   + H    +    +++                   + E W++  +T   PT+AYGT+EFQGGPHPT+ARYVR+ Y T+P  ++HLLL EW +RVPNLVIS++GGLAN  LQ K+++V   GL++AAKTTG WV+T GLD GVT+H+GEAL +E+HI+G+NIVALGI+PWG VQHR+ L+G    C YYS   +   Q A L+ HHNYFLLADNGT  KFG E+ LRR LE+YLA QPI MR +G   KSR+P+V VL+EGG Q FR VFELVT  YPVPVVVC+GSGRAADLLAFMHRY++E+G+LP  ++EQ++ T+ RTF L   E+E LY E++LC+KRR LI+++RM +G  D ID+ ILTALLQ S  KLT A+QL+LTMAW+RPDIARS++F   + W +  L+NAM DAL+NDRL+FVKLLL  G+ + RFL V RLE  Y       + SF+ + +K+  +  +Q +TLR VG LIE L+GGGYQH YC K   G+  LP  +                        M D  SS       Y+N  +  E G                          D SS    FRYPYTELLQW +LTRRY MA +MV++GEESIAK+L     L       +  ++E E  +E +   + FE L+  LQDHCY+H+P++ KRLL YEL+ FS +T +SLA++C+SK F+GH CTQ+ILNDLWYGGLR GK VG KV   ++ + +  ++P +   L T   ++ +EFKTK+ELA QPQTL+EYL+
Sbjct:   41 WIEENITMLECAKYIPSRRSMVNSRCYCGLSVKNHAPNVRLDAVTQLGAECFRSLLLKNGSRRTASQTERWHVKTHTREMPTNAYGTVEFQGGPHPTRARYVRLHYDTSPETLMHLLLHEWRIRVPNLVISMLGGLANAPLQNKIQRVVQSGLLRAAKTTGAWVITNGLDIGVTRHIGEALGDEVHIRGSNIVALGIAPWGYVQHRETLIGLNHTCAYYSQGWRPGCQDAPLDPHHNYFLLADNGTTGKFGGELCLRRRLEQYLAQQPIDMRRYGG-SKSRIPIVGVLLEGGQQTFRTVFELVTGRYPVPVVVCDGSGRAADLLAFMHRYANEDGDLPAPLKEQIISTISRTFQLHRHESEGLYSELRLCMKRRHLISIFRMGEGDSDEIDITILTALLQVSGHKLTPAEQLSLTMAWDRPDIARSKVFTSCSTWSTTTLENAMADALLNDRLEFVKLLLAKGLGIQRFLTVGRLEELYIAASDVNNRSFHKLFAKI--MGARQRITLRAVGQLIENLIGGGYQHSYCDKSGFGR--LPSFEHRSASADVGSYSSDPHLAGLVHRLMADRKSSFPRKSVTYANIDHAVEHGGLKFPASLGHMVTGHKQHSTSVLNTEDPSSRDCVFRYPYTELLQWALLTRRYKMARFMVLAGEESIAKALFSVKLLRGIRHASVHEESEVEVAKEFRTQEDLFERLAFDLQDHCYRHDPDQAKRLLIYELRAFSNNTCLSLAHMCESKVFIGHKCTQSILNDLWYGGLRNGKMVGAKVALLLMGMLLPPVYPIIGYCLST--RSKFLEFKTKEELAQQPQTLQEYLD 851          

Query: 3100 TFNNLSFTKCAPD---ALFEFCQENPQISPGTQLSCRKKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYVHIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPVDFPEESRLTPLAWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMK--FCFYFFKR-----------------------------KYTHNNKPGMNDNNFDHRNHSA-GLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGNVIKRTLQCMDQTQFQIGELHSRFNVMR 4458
            T +N   T   PD    LF     +       QLS RK+IYEFF AP+T+FYL+VI +++ ++L I L           + E+Y+Y+HI T FLD FR+     G N  QKM+VH  + WN +D       +I   +RYF                          I++WG+NL+I+  A W ++  ELMQ WR  G  +  + +MI+ ++P + ++ + + AFG +R+GIMY     + + ++ K   LKPYFM+YGEVYA EIDP D+P ES  TPL   VP+A V+F+L +++V +S++IA   DI+ +M++ S  VY YLRY +II+YESRP  PPPFI++ W+Y+LL  +Y   K        +R                             K   +++P  +   F   N +A GLKLFL   E+EKLHDFEEECV+DYW+ ++  +  +         Q +D  QF+I E+H   N +R
Sbjct: 1261 TLHNFQLTPGTPDRLEGLFTSVTSH-------QLSWRKRIYEFFSAPVTRFYLHVILYLVFLVLYIGLCLHTIPARSWSFLEIYVYLHIFTYFLDKFREVTLVRGSNYLQKMRVHLGAFWNTYDLVMCSVSMIGIGLRYFGMIYL--------------------PIYMWGKNLLIVCCAMWQMRFFELMQIWRFSGPIIYTVFMMIRVMIPMLSLVFLPLLAFGTMREGIMYPNRTHVDLDSV-KGTMLKPYFMIYGEVYADEIDPNDWPPESINTPLKEAVPIATVIFLLYSIIVFISVVIATFNDIFSRMRQQSELVYNYLRYAVIIEYESRPLLPPPFIVISWVYMLLLHVYRVRKNRRALAALERLSSDGRSTENDSNIPKPKRQTKGDTIEFSKGQKDSRPPPSPGVFSTSNETAVGLKLFLDSAEVEKLHDFEEECVDDYWRESRKLESLDAERRTDVLNQKLDHLQFRISEIHIHQNQLR 1720          

Query:  226 WIDDNILKLECNRF----HPKSNGYCACGRPAEEH-------------------INKNQFHNSSKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQ-AVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRMEDGCPD-IDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQILTLRQVGSLIEILMGGGYQHQYCQKLSP---------GKSLLPVTDMC------DTLSS-VDNFKNLYSNSLN-----------------------------------------ENEIGVDNSSN--------FRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXX-XXXXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALP-ITLLTLKSNRLIEFKTKQELALQPQTLEEYLN 2439
            WI+ NI+ LEC +F    H KSN  C+CG    EH                   I+ N  ++     NE W++  +T   PT+AYGT+EFQGGPHPTKARYVR+ Y T P  VLHLLL EW +RVPNLVISI+GGLAN  LQ KL++V   G+++AAKTTG W+VT GLD GVT+H+GEALK+E+HI+G+NIVALGI+PWG VQHR+ L+G +  C YYS   +  +Q A LN  HNYFLLADNGT  KFG E+ LRR LE+YLA QPI MR +G   KSRVP+V VL+EGG Q FR VFELVT   PVP+VVC+GSGRAADLLAFMHRY++E+G+L   +R+Q++  + R F +   EAE LY E+KLC+KRR LI+V+RM +G  D ID+ ILTALLQ S   LT A+QL+LTMAWNRPDIARS++F     W    L+NAM DAL+NDRL+FV+LLL  G+ + RFL   RLE  YN+     + SF+ + +KV  L  KQ +TLR VG LIE L+GGGYQH YC K S          G   LP  ++        T+S  VDN  +  SN LN                                         +  +    SSN        FRYPYTELLQWT+LTRR DMA ++V++GEES+AK+L     L       LD + + E L E +      E L+V LQDHCY+H+ ++ KRLL YELQ FS +T +SLAY+C+SK F+GH CTQ ILNDLWYGGLR+G  VG KV ++L+ +I + P  P I     K ++ +EFKTK+ELA QPQTL+E+L+
Sbjct:   43 WIEQNIVCLECAKFVFARHSKSNPCCSCGLTFSEHPSNVQIEALTQQNLNLQPDISINGDYHLKPTNNERWHVKTHTQEMPTNAYGTVEFQGGPHPTKARYVRLHYETCPELVLHLLLHEWKIRVPNLVISIVGGLANAPLQAKLQQVVKHGILRAAKTTGAWIVTNGLDIGVTRHIGEALKDEVHIRGSNIVALGIAPWGYVQHRETLIGLDNTCSYYSQGWRPGRQEAPLNPDHNYFLLADNGTSGKFGGELGLRRRLEQYLAQQPIDMRRYGG-SKSRVPIVGVLLEGGTQTFRTVFELVTGRNPVPIVVCDGSGRAADLLAFMHRYANEDGDLSTQLRDQMVANISRAFQIRRFEAEGLYSELKLCMKRRHLISVFRMGEGDSDEIDITILTALLQVSGQNLTPAEQLSLTMAWNRPDIARSKVFAKFNNWSKTTLENAMADALLNDRLEFVQLLLTKGLRIQRFLTRERLEELYNVDV--NNQSFHKLFAKV--LGTKQKITLRSVGQLIENLVGGGYQHSYCSKPSTADLMGSPNHGNGWLPNVNVTFANKHGSTVSEPVDNKTSRSSNILNNTSDKSIPPCTLNPGSISNLITSKELVTQHITNIINRQHTSQQHVPYSTSSNDINQSNRYFRYPYTELLQWTLLTRRLDMAKFLVLAGEESVAKALFSVKLLRSIRHVTLDEETDIELLNECRSHELALERLAVDLQDHCYRHDQDQAKRLLTYELQAFSKNTCLSLAYMCESKVFIGHPCTQAILNDLWYGGLRKGDLVGAKVALILIGLI-VPPLYPLIAFFFTKKSKFLEFKTKEELAQQPQTLQEHLD 866          

Query:  289 CACGRPAEEH-------INKNQFHNSSKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEW----------------QSPV---------------------------------------LDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGD-FSFNSMISKVCNLKKKQILTLRQVGSLIEILMGGGYQHQYCQKLSPGKSLLPVTDMCDTLSSVDNFKNLYSNSLNENE-----------------IGVDNS--SNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXXXXXXXXXXXXXXXDNESEYLEELK--LWGN--KFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQE 2400
            C+CG+   +H        +K      S+   E W+++ +T   PTDAYGT+EFQGG H  KA Y+R+SY + P ++LHL++++W L +P L+IS+ GGL NFDLQPKLK+VF  GL+KAA TTG W+ T G+ TGV +HVG+ALK+        + A+GI+PWGIV++++ L+G++   PY +++N   K +VLN  H++F+LADNGT  K+GAE+ LRR LE++++ Q I    + RLG+  VP+V +++EGG     +V E + +E PVPVVVC+GSGRA+D+++F H+Y++E+G +   VR+Q+L T+Q+TF+    +A+ +Y  +  C+K+RELITV+RM  +G  DI++AILTALL+ +    +  DQL+L +AWNR DIARSQIF     W                +SP                                        L+ AM+DAL+ DR+DFVKLL+ENGVN+H FL + RLE  YN R    +   F     K  NL     +TL  +G ++E LMGG Y+  Y +K            + + L  +   K L    + +++                 I VD+   S F+YP+ EL+ W +L +R  MA+++   GEE++AK+L+A KL K M       ++SE ++++   L  N  +F  L+  L D  YKH+ +   +LL YELQ +S  T + LA   + + F+ H C+Q +L D+W G LR GK  GLKV++ +     IFP   I LL  +    + + T +E
Sbjct:    7 CSCGQLVTQHAPIPPSATSKGGEEGQSEPAAERWSVLKHTQLLPTDAYGTIEFQGGGHANKAMYIRVSYDSKPDNLLHLMVKDWQLELPTLLISVHGGLQNFDLQPKLKQVFGKGLIKAAVTTGAWIFTGGVSTGVIRHVGDALKDHSSKSRGRVCAIGIAPWGIVENKEDLIGRDVTRPYQTMSNPLSKLSVLNSSHSHFILADNGTHGKYGAEVRLRRQLEKHISLQKI----NTRLGQG-VPLVCLILEGGPNVITIVLESLREEPPVPVVVCDGSGRASDIISFAHKYTEEDGLVNEGVRDQLLVTLQKTFNYNRNQAQQIYLMVMECMKKRELITVFRMGSEGQQDIEMAILTALLKGT--NASAPDQLSLALAWNRVDIARSQIFVHGQHWPSAGSLPAASIPQDRPKSPTRGSKSKAARAKKGRRGKPKPEPPEETDPRKLELLNWVNSLEQAMMDALVLDRVDFVKLLIENGVNIHHFLTIPRLEELYNTRLGPTNTLHFVVRDVKKGNLPPDYQITLIDIGLVLEFLMGGAYRCNYTRK--------SFRTLYNNLYGLKRPKALKLLGMEDDDPRPKGKKKKKKKEEEIDIDVDDPEVSRFQYPFHELMVWAVLMKRQKMALFLWQRGEEAMAKALVACKLYKAMAHE---SSQSELVDDISQDLDNNSKEFGQLAYELLDQSYKHDEQVAMKLLTYELQNWSNSTCLKLAVAAKHRDFIAHTCSQMLLTDMWMGCLRMGKSNGLKVILGI-----IFPP-AILLLDFRIGDDMSYHTSKE 773          

Query: 3202 KKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYV-HIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEV-------YAAEIDPV--------DFPEESRLTPLAWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGNVIKRTLQCMDQTQFQIGELHSRFNVMRV 4461
            KKIY F+ AP TKF+ N I++++ ++L   +  +K  +ER    + +I + +IIT  L+  R+   +    + QK+ V  E  WN  D       L+A S+       F        +NS             +GR +  +   +W I+ L++    +  G Y+ MI  M+  ++  V+I+ V++ +FGV RQ I++    +     + +NI+  PY+M+YGEV       YA EI+P         D  +     P AW  P  M  ++L A +++++L+IA   + + ++K  S +V+ + RY +I+ +  RP  PPP II   IYI+LK++    K                   +   D R+   GLKL LSV+E++ L++FEE+CVE+Y++  +  ++      I+ T + ++    ++ E++ R + M+ 
Sbjct:  817 KKIYYFYNAPFTKFWFNTIAYLVYLMLYNYIILVK--MERWPSLQEWIVISYIITLGLEKVRQILMSEPGKLKQKINVWLEDYWNITD-------LVAISM-------FLLGLLLRLQNS----------YMGYGRVIYCVDIIFWYIRVLDIFGVNKYLGPYVMMIGKMMIDMLYFVVIMLVVLMSFGVARQAILHPD--EEPTWRLARNIFYMPYWMIYGEVFADSIDLYAMEINPPCGENMYDEDGKKLPPCIPGAWLTPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHDRPVLPPPLIIFSHIYIVLKRLCCRCKRR---------------RKEGELDERDR--GLKLILSVEELKSLYEFEEQCVEEYFREKEDEEQSSNDERIRVTTERVENMSMRLEEVNEREHTMKA 1207          

Query:  223 NWIDDNILKLECNRFHPKSNG---------------YCACGRPAEEHIN---------KNQFHNSSKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKV--CNLKKKQILTLRQVGSLIEILMGGGYQHQYCQKL-------------------SPGKSLL----PVTDMCDT---------LSSVDNFK-------NLYSNSLNENEIGVDN--SSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXX-XXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGL--REGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEY 2433
            +WI+    K EC    P S                  C CGR   +H+           +     ++  +E W++ ++T   PTDAYG + FQGG H  +A+YVR+S+ + P  +L L+L+EW + +P +VIS+ GG+ NFDL P++K+V   GL+KAA TTG W++T G++TGV KHVG+ALK         I  +GI+PWG++++R  L+G++ + PY ++ N   K  VLN  H++F+L DNGTV K+GAE+ LRR LE+++  Q    R H R+G+  VPVVA++ EGG      V E + +  PVPVVVCEG+GRAAD+L+F+H+ ++++G LP  V   ++ TV++TF+L   +A  L++ +  C+K +ELITV+ +  +   DIDVAIL ALL+ +    +  DQL LT+AW+R DIA+  +F    +     L+ AM+DAL+ DR+DFVKLL+ENGV+MHRFL +SRLE  YN +    + +   ++  V   NL     +TL  VG +IE LMGG Y+  Y +K                    S G  L     P +   D          + +   +K       +L      E  + +D+  +  F YP+ ELL W +L +R  M+++    GEES+AK+L+A         +    D   +  EELK + N+F  L+V L +  ++ +   + +LL YEL+ +S  T + LA   + +PF+ H CTQ +L+D+W   L  R+  W       V+LSI+     +P  +L L      E+K+K E+A  PQ+ + +
Sbjct:    5 SWIESTFTKRECVYILPVSKDPHRCLPGCQICQQLVRCCCGRLVRQHVGFTASLAMKYSDMKLGEAQPPHEEWSVENHTEQSPTDAYGIINFQGGSHSYRAKYVRLSHDSRPEAILRLMLKEWQMELPKIVISVHGGIQNFDLHPRIKQVVGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKEHSSRSARKICTIGIAPWGVIENRNDLIGRDVVAPYQTLLNPLSKLNVLNNLHSHFILVDNGTVGKYGAEVNLRRDLEKHINLQ----RIHARIGQG-VPVVALIFEGGPNVILTVLEYLQESPPVPVVVCEGTGRAADILSFVHKQTEDDGGLPDGVETDIIATVKKTFNLSQNDAVHLFQTLMECMKNKELITVFHVGSEDHQDIDVAILKALLKGT--DASAFDQLVLTLAWDRVDIAKDHVFVYGQKLLVDSLEQAMLDALVMDRVDFVKLLIENGVSMHRFLTISRLEELYNTKQSPTNPNLFQLVRDVKQGNLPPNYKITLIDVGLVIEYLMGGTYRCNYTRKRFRIIYNNLHGNNRRSGRAPSSGPPLRKNHEPFSIQADKKEKTRHNHFIKTAQPYKPKLESSSDLQQKRSREEVVDIDDPETRRFPYPFNELLVWAVLMKRQKMSLFFWQHGEESMAKALVACKLCRSMCYEAKKSDVVDDTSEELKEYSNEFGTLAVDLLEQSFRQDELMSMKLLTYELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMERLNMRKNSWYK-----VILSIL-----VPPAILAL------EYKSKAEMAHIPQSQDAH 789          

Query: 3148 EFCQENPQISPGTQLSCRKKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYVHIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPVDFPEESRLTPL----AWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGN--VIKRTLQCMDQTQFQIGELHSRFNVMR 4458
            E   E   ++   +L   +K + F++API KF+ N + +++ ++L   +  +K  +      E  + ++I T+ ++  R+   + G  I+QK+KV F   +N  DF       + F +R+                     S N   +F+ GR +  L   +W ++ L+++   +  G Y+ MI  M+  +   V+I+ V++  +GV R+ I+Y      +  +++ ++  +PY+M+YGEVYA EID      E+ +  L     W  P    +++    +++++L+IA   ++Y ++   S  V+ Y RY  I+ Y  +P  PPP II           Y    F  +  KR+                ++ + G KLFL+ ++ +KLHDFEE+CVE Y+ H K  D+F  G+   I+ T   ++    Q+ E+ +R N ++
Sbjct:  821 EVKHETEVVTRSRRLPIMRKFHAFYHAPIVKFWTNTLFYLVFLMLYSYVVLVKLPIFPSPQ-EWAVILYIFTSAIEKIREMFMSEGGKISQKIKVWFSDYFNRSDFIAIVMFAVGFGLRF--------------------GSGN---VFIAGRLIYCLNIIFWYVRLLDILAVNQQAGPYVMMIGKMVANMFYIVVIMCVVLVTYGVPRKAILYPN--SEAEWSLIIDVVFQPYWMMYGEVYAYEIDVCANSTENNMDHLCTTGVWLTPALQAVYLFIQYILMVNLLIAFFNNVYLQVMSISNLVWKYQRYHFIMAYHDKPVLPPPLIIF----------YHISSFLSFLCKRR---------------KKDSAYGPKLFLTEEDQKKLHDFEEQCVETYF-HEK-DDKFHSGSEERIRLTSDRVETMSIQLREVGNRVNFIK 1210          

Query:  223 NWIDDNILKLECNRFHPKSNG---------------YCACGRPAEEHIN---------KNQFHNSSKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKV--CNLKKKQILTLRQVGSLIEILMGGGYQHQYCQKL-------------------SPGKSLL----PVTDMCDT---------LSSVDNFK-------NLYSNSLNENEIGVDN--SSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXX-XXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGL--REGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEY 2433
            +WI+    K EC    P S                  C CGR   +H+           +     ++  +E W++ ++T   PTDAYG + FQGG H  +A+YVR+S+ + P  +L L+L+EW + +P +VIS+ GG+ NFDL P++K+V   GL+KAA TTG W++T G++TGV KHVG+ALK         I  +GI+PWG++++R  L+G++ + PY ++ N   K  VLN  H++F+L DNGTV K+GAE+ LRR LE+++  Q    R H R+G+  VPVVA++ EGG      V E + +  PVPVVVCEG+GRAAD+L+F+H+ ++++G LP  V   ++ TV++TF+L   +A  L++ +  C+K +ELITV+ +  +   DIDVAIL ALL+ +    +  DQL LT+AW+R DIA+  +F    +     L+ AM+DAL+ DR+DFVKLL+ENGV+MHRFL +SRLE  YN +    + +   ++  V   NL     +TL  VG +IE LMGG Y+  Y +K                    S G  L     P +   D          + +   +K       +L      E  + +D+  +  F YP+ ELL W +L +R  M+++    GEES+AK+L+A         +    D   +  EELK + N+F  L+V L +  ++ +   + +LL YEL+ +S  T + LA   + +PF+ H CTQ +L+D+W   L  R+  W       V+LSI+     +P  +L L      E+K+K E+A  PQ+ + +
Sbjct:    5 SWIESTFTKRECVYILPVSKDPHRCLPGCQICQQLVRCCCGRLVRQHVGFTASLAMKYSDMKLGEAQPPHEEWSVENHTEQSPTDAYGIINFQGGSHSYRAKYVRLSHDSRPEAILRLMLKEWQMELPKIVISVHGGIQNFDLHPRIKQVVGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKEHSSRSARKICTIGIAPWGVIENRNDLIGRDVVAPYQTLLNPLSKLNVLNNLHSHFILVDNGTVGKYGAEVNLRRDLEKHINLQ----RIHARIGQG-VPVVALIFEGGPNVILTVLEYLQESPPVPVVVCEGTGRAADILSFVHKQTEDDGGLPDGVETDIIATVKKTFNLSQNDAVHLFQTLMECMKNKELITVFHVGSEDHQDIDVAILKALLKGT--DASAFDQLVLTLAWDRVDIAKDHVFVYGQKLLVDSLEQAMLDALVMDRVDFVKLLIENGVSMHRFLTISRLEELYNTKQSPTNPNLFQLVRDVKQGNLPPNYKITLIDVGLVIEYLMGGTYRCNYTRKRFRIIYNNLHGNNRRSGRAPSSGPPLRKNHEPFSIQADKKEKTRHNHFIKTAQPYKPKLESSSDLQQKRSREEVVDIDDPETRRFPYPFNELLVWAVLMKRQKMSLFFWQHGEESMAKALVACKLCRSMCYEAKKSDVVDDTSEELKEYSNEFGTLAVDLLEQSFRQDELMSMKLLTYELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMERLNMRKNSWYK-----VILSIL-----VPPAILAL------EYKSKAEMAHIPQSQDAH 789          

Query: 3148 EFCQENPQISPGTQLSCRKKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYVHIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPVDFPEESRLTPL----AWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGN--VIKRTLQCMDQTQFQIGELHSRFNVMR 4458
            E   E   ++   +L   +K + F++API KF+ N + +++ ++L   +  +K  +      E  + ++I T+ ++  R+   + G  I+QK+KV F   +N  DF       + F +R+                     S N   +F+ GR +  L   +W ++ L+++   +  G Y+ MI  M+  +   V+I+ V++  +GV R+ I+Y      +  +++ ++  +PY+M+YGEVYA EID      E+ +  L     W  P    +++    +++++L+IA   ++Y ++   S  V+ Y RY  I+ Y  +P  PPP II           Y    F  +  KR+                ++ + G KLFL+ ++ +KLHDFEE+CVE Y+ H K  D+F  G+   I+ T   ++    Q+ E+ +R N ++
Sbjct:  821 EVKHETEVVTRSRRLPIMRKFHAFYHAPIVKFWTNTLFYLVFLMLYSYVVLVKLPIFPSPQ-EWAVILYIFTSAIEKIREMFMSEGGKISQKIKVWFSDYFNRSDFIAIVMFAVGFGLRF--------------------GSGN---VFIAGRLIYCLNIIFWYVRLLDILAVNQQAGPYVMMIGKMVANMFYIVVIMCVVLVTYGVPRKAILYPN--SEAEWSLIIDVVFQPYWMMYGEVYAYEIDVCANSTENNMDHLCTTGVWLTPALQAVYLFIQYILMVNLLIAFFNNVYLQVMSISNLVWKYQRYHFIMAYHDKPVLPPPLIIF----------YHISSFLSFLCKRR---------------KKDSAYGPKLFLTEEDQKKLHDFEEQCVETYF-HEK-DDKFHSGSEERIRLTSDRVETMSIQLREVGNRVNFIK 1210          

Query:  223 NWIDDNILKLECNRFHPKSNG---------------YCACGRPAEEHIN---------KNQFHNSSKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKV--CNLKKKQILTLRQVGSLIEILMGGGYQHQYCQKL-------------------SPGKSLL----PVTDMCDT---------LSSVDNFK-------NLYSNSLNENEIGVDN--SSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXX-XXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGL--REGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEY 2433
            +WI+    K EC    P S                  C CGR   +H+           +     ++  +E W++ ++T   PTDAYG + FQGG H  +A+YVR+S+ + P  +L L+L+EW + +P +VIS+ GG+ NFDL P++K+V   GL+KAA TTG W++T G++TGV KHVG+ALK         I  +GI+PWG++++R  L+G++ + PY ++ N   K  VLN  H++F+L DNGTV K+GAE+ LRR LE+++  Q    R H R+G+  VPVVA++ EGG      V E + +  PVPVVVCEG+GRAAD+L+F+H+ ++++G LP  V   ++ TV++TF+L   +A  L++ +  C+K +ELITV+ +  +   DIDVAIL ALL+ +    +  DQL LT+AW+R DIA+  +F    +     L+ AM+DAL+ DR+DFVKLL+ENGV+MHRFL +SRLE  YN +    + +   ++  V   NL     +TL  VG +IE LMGG Y+  Y +K                    S G  L     P +   D          + +   +K       +L      E  + +D+  +  F YP+ ELL W +L +R  M+++    GEES+AK+L+A         +    D   +  EELK + N+F  L+V L +  ++ +   + +LL YEL+ +S  T + LA   + +PF+ H CTQ +L+D+W   L  R+  W       V+LSI+     +P  +L L      E+K+K E+A  PQ+ + +
Sbjct:   15 SWIESTFTKRECVYILPVSKDPHRCLPGCQICQQLVRCCCGRLVRQHVGFTASLAMKYSDMKLGEAQPPHEEWSVENHTEQSPTDAYGIINFQGGSHSYRAKYVRLSHDSRPEAILRLMLKEWQMELPKIVISVHGGIQNFDLHPRIKQVVGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKEHSSRSARKICTIGIAPWGVIENRNDLIGRDVVAPYQTLLNPLSKLNVLNNLHSHFILVDNGTVGKYGAEVNLRRDLEKHINLQ----RIHARIGQG-VPVVALIFEGGPNVILTVLEYLQESPPVPVVVCEGTGRAADILSFVHKQTEDDGGLPDGVETDIIATVKKTFNLSQNDAVHLFQTLMECMKNKELITVFHVGSEDHQDIDVAILKALLKGT--DASAFDQLVLTLAWDRVDIAKDHVFVYGQKLLVDSLEQAMLDALVMDRVDFVKLLIENGVSMHRFLTISRLEELYNTKQSPTNPNLFQLVRDVKQGNLPPNYKITLIDVGLVIEYLMGGTYRCNYTRKRFRIIYNNLHGNNRRSGRAPSSGPPLRKNHEPFSIQADKKEKTRHNHFIKTAQPYKPKLESSSDLQQKRSREEVVDIDDPETRRFPYPFNELLVWAVLMKRQKMSLFFWQHGEESMAKALVACKLCRSMCYEAKKSDVVDDTSEELKEYSNEFGTLAVDLLEQSFRQDELMSMKLLTYELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMERLNMRKNSWYK-----VILSIL-----VPPAILAL------EYKSKAEMAHIPQSQDAH 799          

Query: 3148 EFCQENPQISPGTQLSCRKKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYVHIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPVDFPEESRLTPL----AWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGN--VIKRTLQCMDQTQFQIGELHSRFNVMR 4458
            E   E   ++   +L   +K + F++API KF+ N + +++ ++L   +  +K  +      E  + ++I T+ ++  R+   + G  I+QK+KV F   +N  DF       + F +R+                     S N   +F+ GR +  L   +W ++ L+++   +  G Y+ MI  M+  +   V+I+ V++  +GV R+ I+Y      +  +++ ++  +PY+M+YGEVYA EID      E+ +  L     W  P    +++    +++++L+IA   ++Y ++   S  V+ Y RY  I+ Y  +P  PPP II           Y    F  +  KR+                ++ + G KLFL+ ++ +KLHDFEE+CVE Y+ H K  D+F  G+   I+ T   ++    Q+ E+ +R N ++
Sbjct:  831 EVKHETEVVTRSRRLPIMRKFHAFYHAPIVKFWTNTLFYLVFLMLYSYVVLVKLPIFPSPQ-EWAVILYIFTSAIEKIREMFMSEGGKISQKIKVWFSDYFNRSDFIAIVMFAVGFGLRF--------------------GSGN---VFIAGRLIYCLNIIFWYVRLLDILAVNQQAGPYVMMIGKMVANMFYIVVIMCVVLVTYGVPRKAILYPN--SEAEWSLIIDVVFQPYWMMYGEVYAYEIDVCANSTENNMDHLCTTGVWLTPALQAVYLFIQYILMVNLLIAFFNNVYLQVMSISNLVWKYQRYHFIMAYHDKPVLPPPLIIF----------YHISSFLSFLCKRR---------------KKDSAYGPKLFLTEEDQKKLHDFEEQCVETYF-HEK-DDKFHSGSEERIRLTSDRVETMSIQLREVGNRVNFIK 1220          

Query:  223 NWIDDNILKLECNRFHPKSNG---------------YCACGRPAEEHIN---------KNQFHNSSKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKV--CNLKKKQILTLRQVGSLIEILMGGGYQHQYCQKL-------------------SPGKSLL----PVTDMCDT---------LSSVDNFK-------NLYSNSLNENEIGVDN--SSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXX-XXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGL--REGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEY 2433
            +WI+    K EC    P S                  C CGR   +H+           +     ++  +E W++ ++T   PTDAYG + FQGG H  +A+YVR+S+ + P  +L L+L+EW + +P +VIS+ GG+ NFDL P++K+V   GL+KAA TTG W++T G++TGV KHVG+ALK         I  +GI+PWG++++R  L+G++ + PY ++ N   K  VLN  H++F+L DNGTV K+GAE+ LRR LE+++  Q    R H R+G+  VPVVA++ EGG      V E + +  PVPVVVCEG+GRAAD+L+F+H+ ++++G LP  V   ++ TV++TF+L   +A  L++ +  C+K +ELITV+ +  +   DIDVAIL ALL+ +    +  DQL LT+AW+R DIA+  +F    +     L+ AM+DAL+ DR+DFVKLL+ENGV+MHRFL +SRLE  YN +    + +   ++  V   NL     +TL  VG +IE LMGG Y+  Y +K                    S G  L     P +   D          + +   +K       +L      E  + +D+  +  F YP+ ELL W +L +R  M+++    GEES+AK+L+A         +    D   +  EELK + N+F  L+V L +  ++ +   + +LL YEL+ +S  T + LA   + +PF+ H CTQ +L+D+W   L  R+  W       V+LSI+     +P  +L L      E+K+K E+A  PQ+ + +
Sbjct:   22 SWIESTFTKRECVYILPVSKDPHRCLPGCQICQQLVRCCCGRLVRQHVGFTASLAMKYSDMKLGEAQPPHEEWSVENHTEQSPTDAYGIINFQGGSHSYRAKYVRLSHDSRPEAILRLMLKEWQMELPKIVISVHGGIQNFDLHPRIKQVVGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKEHSSRSARKICTIGIAPWGVIENRNDLIGRDVVAPYQTLLNPLSKLNVLNNLHSHFILVDNGTVGKYGAEVNLRRDLEKHINLQ----RIHARIGQG-VPVVALIFEGGPNVILTVLEYLQESPPVPVVVCEGTGRAADILSFVHKQTEDDGGLPDGVETDIIATVKKTFNLSQNDAVHLFQTLMECMKNKELITVFHVGSEDHQDIDVAILKALLKGT--DASAFDQLVLTLAWDRVDIAKDHVFVYGQKLLVDSLEQAMLDALVMDRVDFVKLLIENGVSMHRFLTISRLEELYNTKQSPTNPNLFQLVRDVKQGNLPPNYKITLIDVGLVIEYLMGGTYRCNYTRKRFRIIYNNLHGNNRRSGRAPSSGPPLRKNHEPFSIQADKKEKTRHNHFIKTAQPYKPKLESSSDLQQKRSREEVVDIDDPETRRFPYPFNELLVWAVLMKRQKMSLFFWQHGEESMAKALVACKLCRSMCYEAKKSDVVDDTSEELKEYSNEFGTLAVDLLEQSFRQDELMSMKLLTYELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMERLNMRKNSWYK-----VILSIL-----VPPAILAL------EYKSKAEMAHIPQSQDAH 806          

Query: 3148 EFCQENPQISPGTQLSCRKKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYVHIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPVDFPEESRLTPL----AWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGN--VIKRTLQCMDQTQFQIGELHSRFNVMR 4458
            E   E   ++   +L   +K + F++API KF+ N + +++ ++L   +  +K  +      E  + ++I T+ ++  R+   + G  I+QK+KV F   +N  DF       + F +R+                     S N   +F+ GR +  L   +W ++ L+++   +  G Y+ MI  M+  +   V+I+ V++  +GV R+ I+Y      +  +++ ++  +PY+M+YGEVYA EID      E+ +  L     W  P    +++    +++++L+IA   ++Y ++   S  V+ Y RY  I+ Y  +P  PPP II           Y    F  +  KR+                ++ + G KLFL+ ++ +KLHDFEE+CVE Y+ H K  D+F  G+   I+ T   ++    Q+ E+ +R N ++
Sbjct:  838 EVKHETEVVTRSRRLPIMRKFHAFYHAPIVKFWTNTLFYLVFLMLYSYVVLVKLPIFPSPQ-EWAVILYIFTSAIEKIREMFMSEGGKISQKIKVWFSDYFNRSDFIAIVMFAVGFGLRF--------------------GSGN---VFIAGRLIYCLNIIFWYVRLLDILAVNQQAGPYVMMIGKMVANMFYIVVIMCVVLVTYGVPRKAILYPN--SEAEWSLIIDVVFQPYWMMYGEVYAYEIDVCANSTENNMDHLCTTGVWLTPALQAVYLFIQYILMVNLLIAFFNNVYLQVMSISNLVWKYQRYHFIMAYHDKPVLPPPLIIF----------YHISSFLSFLCKRR---------------KKDSAYGPKLFLTEEDQKKLHDFEEQCVETYF-HEK-DDKFHSGSEERIRLTSDRVETMSIQLREVGNRVNFIK 1227          

Query:  454 RYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEK--ICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPV----LDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQILTLRQVGSLIEILMGGGYQHQYCQKLSPGKSLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGV--DNS----SNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXXXXXXXXXXXXXXXDNESEYLEELKLWGN--KFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGL--REGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLE 2427
            +Y R+SY + P  +L L+++EW + +P L+IS+ GGL NF+L PKLK+VF  GL+KAA TTG W+ T G++TGV  HVG ALK       + I  +GI+PWG++++R  L+G++   + PY +++N   K  +LN  H++F+L D+GTV K+GAE  LRR LE+++AT   R      +G+  VPVV ++ EGG      V E + +E PVPVVVCEG+GRAAD+LAF+H+ +D+ GEL   + ++++ T+++TF+    +A  L + +  C++R+ELITV+    +   D+D+AILTALL+ +    + ADQL L +AW+R DIA++ +F     W   +        M+DAL+ DR+DFVKLL+ENGV+MH+FL ++RLE  YN        +   ++ +  +L     +TL  VG +IE LMGG ++  Y +K      LL         +SVDN +         + +GV  D S    S F YP+ ELL W +L +R  MAM+    GEES+AK+L+A KL + +        E E L+  +LW    KF  L++ L D  ++ +     +LL YEL+ +S  T + LA   + +PF+ H CTQ +L D+W G L  R+  W       V+LSI+     +P ++L      ++E+K+K E++  PQ+ E
Sbjct:    1 QYARVSYDSRPDLLLQLMVKEWQMELPRLLISVHGGLQNFELHPKLKQVFSKGLIKAALTTGAWIFTGGVNTGVVNHVGNALKEHASRSSHKICTIGIAPWGVIENRGDLVGQDSHVVSPYQTLSNPLSKLNLLNSLHSHFILVDDGTVGKYGAEAQLRRELEKHIATVACR----AGMGQG-VPVVGLVAEGGPNVIVTVLEYLLEEPPVPVVVCEGTGRAADILAFLHKNTDDTGELCDGLHDEIVGTIKKTFNFSHGQAMHLLQTLLECMRRKELITVFHTGSEDHSDVDLAILTALLKGT--NFSSADQLNLALAWDRVDIAKNHVFVYGQHWMVRLEWARWRRPMLDALVMDRVDFVKLLIENGVSMHKFLTITRLEELYNTSDHHQMSNLRILLHRFSHLPPDYKITLIDVGLVIEFLMGGAFRSMYTRKRF---RLLYHNLYGQHRASVDNTRQRKQKMSTASGVGVTLDGSDPECSCFAYPFNELLAWAVLMKRQRMAMFFWQHGEESLAKALVACKLYRSLAGEAKQSREDE-LKWKRLWCARVKFGQLALDLLDQSFRQDERMAMKLLTYELRNWSNFTCLKLAVSSRHRPFVAHTCTQMLLADMWMGRLNMRKNSWFK-----VILSIL-----MPPSIL------MLEYKSKAEMSHIPQSEE 648          

Query: 3157 QENPQISPGTQLSCRKKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYVHIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPVDFPEESRLTPLAWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESR 4095
            +E   I P + LS  ++IYEF++API KF+ N +++I  ++L   +  +K   +     E ++ +++  + ++  R+   +      QK+KV  +  WN  D        +A ++R                        + S + +  + +  L   +W ++ L++    +  G Y+ MI  M+ Q    ++I+++++ +FGV RQ I+++   D S   + +NI  +PY+M++GEVYA EID     E    T  A+  P    +++    +++++L+IA   +IY + K  S K++ + RY   + Y  +
Sbjct:  710 EEGIWIRP-SGLSLSRRIYEFYHAPIVKFWFNTLAYIGFLMLFTYVVLVKLQ-QLPSVQEWFVILYLFMSAIERVREIFMSEPGKFGQKIKVWLDGYWNINDSLGILLFFVAVALR------------------------SQSHLLIEAKIVYSLDVIFWYVRLLDVFAVNQNVGPYIMMIGKMMWQQCMLMIIMAIVLLSFGVARQAILFKEA-DPS-WYLARNIVFQPYWMIFGEVYAPEIDNNTDDEYPPCTTGAFITPFLQAVYLFVQYIIMVNLLIAFFNNIYLEAKNISDKLWKFHRYHFTMYYHQK 994          

Query:  457 YVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEK--ICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIR-MRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELIT----VYRMEDGCPDIDVAILTALLQESLPKL-----------TKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLD---NAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQI-----LTLRQVGSLIEILMGGGYQHQYCQKLSPGKSLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGV--DNS----SNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXXXXXXXXXXXXXXXDNESE-YLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGL--REGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLE 2427
            Y R+SY + P  +L L+++EW + +P L+IS+ GGL NF+L PKLK+VF  GL+KAA TTG W+ T G++TGV  HVG ALK       + I  +GI+PWG++++R  L+G++   + PY +++N   K  +LN  H++F+L D+GTV K+GAE  LRR LE+++A Q I  +     +G+  VPVV ++ EGG      V E + +E PVPVVVCEG+GRAAD+LAF+H+ +D+ G        Q +  +Q                   C++R+EL+     V      C     AI      E+L  L           + ADQL L +AW+R DIA++ +F     W + +       M+DAL+ DR+DFVKLL+ENGV+MH+FL ++RLE  YN   + G  +       + N +   +     L    +G+L+ +++GG                      C  + +VDN +         + +GV  D S    S F YP+ ELL W +L +R  MAM+    GEES+AK+L+A KL + +          E   EELK +  +F  L++ L D  ++ +     +LL YEL+ +S  T + LA   + +PF+ H CTQ +L D+W G L  R+  W       V+LSI+     +P ++L      ++E+K+K E++  PQ+ E
Sbjct:    1 YARVSYDSRPDLLLQLMVKEWQMELPRLLISVHGGLQNFELHPKLKQVFSKGLIKAALTTGAWIFTGGVNTGVVNHVGNALKEHASRSSHKICTIGIAPWGVIENRGDLVGQDSHVVSPYQTLSNPLSKLNLLNSLHSHFILVDDGTVGKYGAEAQLRRELEKHIALQKIHTLACRAGMGQG-VPVVGLVAEGGPNVIVTVLEYLLEEPPVPVVVCEGTGRAADILAFLHKNTDDTGWAHTHRHGQAMHLLQTLLE---------------CMRRKELVGTRARVRTHTHTCTHGSAAISGGPSVETLIALHRTGAAAGTNFSSADQLNLALAWDRVDIAKNHVFVYGQHWMALMWARWRRPMLDALVMDRVDFVKLLIENGVSMHKFLTITRLEELYN--TVSGPLTNPPKRPLLANSRSPPVGLNCTLNPPVIGNLLLMILGG---------------------TCSAIQAVDNTRQRKQKMSTASGVGVTLDGSDPECSCFAYPFNELLAWAVLMKRQRMAMFFWQHGEESLAKALVACKLYRSLAGEAKQSEAVEDSSEELKQYSTEFGQLALDLLDQSFRQDERMAMKLLTYELRNWSNFTCLKLAVSSRHRPFVAHTCTQMLLADMWMGRLNMRKNSWFK-----VILSIL-----MPPSIL------MLEYKSKAEMSHIPQSEE 637          

Query: 3157 QENPQISPGTQLSCRKKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKW----SVERIDYFELYIYVHIITNFL---DHFRKFANTAGI------NIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPVDFP---------------EESRLTPLAWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPP 4110
            +E   I P + LS  ++IYEF++API KF+ N +++I  ++L   +  +K     SV+   +  LY+++  I       D  R+    AG+      +  +K+KV  +  WN  D        +A ++R                        + S + +  + +  L   +W ++ L++    +  G Y+ MI  M+  +   V+I+++++ +FGV RQ I+++   D S   + +NI  +PY+M++GEVYA EID +                  E    T  A+  P    +++    +++++L+IA   +IY + K  S K++ + RY   + Y  +P  PP
Sbjct:  657 EEGIWIRP-SGLSLSRRIYEFYHAPIVKFWFNTLAYIGFLMLFTYVVLVKLQQLPSVQEW-FVILYLFMSAIERVREVSDGARETRKAAGLRSDSEASAHRKIKVWLDGYWNINDSLGILLFFVAVALR------------------------SQSHLLIEAKIVYSLDVIFWYVRLLDVFAVNQNVGPYIMMIGKMMANMFSIVIIMAIVLLSFGVARQAILFKEA-DPS-WYLARNIVFQPYWMIFGEVYAPEIDGICVAVLAACENIMKNNTDDEYPPCTTGAFITPFLQAVYLFVQYIIMVNLLIAFFNNIYLEAKNISDKLWKFHRYHFTMYYHQKPILPP 974          

Query:  226 WIDDNI-LKLECNRFHPKSNG-----YCACGRPAEEHINKNQFHNSSKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTT---GTWVVTTGLDTGVTKHVGEALKNEIHIKGN---NIVALGISPWGIVQHRKHLLGKEKICPY-YSIANKNQ-KQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRMEDG---CPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYN------------IRCLKGDFS----FNSMISKV-CNLKKKQILTLRQVGSLIEILMGGGYQHQYCQKLSPGKSLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVDNSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXXXXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFK 2388
            WI  NI +K+ C      + G      C C  P  EH N      +  +  + W    +T   PT+A+G ++F G       ++VR+   T P+ +  L++  W+L VPNL+IS+ GG  NF L+P+L+ +F  GL K A++T   G W++T G   GV K+VGE++++     G+    IVA+GI+ WGI+ +++HL+  +   P  Y +    Q + + L+ +H++F+L DNGT  ++G EIVLR  LE+Y++TQ     + G  G+ R    AV V G   A RL       +  V V  C                    G++   + +     V+   S V  E + +Y ++ +CL     I    +  G   C  + V I  +  + +  + +   QL L +AWNR DIA S+IF    +WQ+  L+  M  AL+ +R +F+ L +E+G+ +  +L  +RLE  YN             R  +G+ S        IS +    K+    +L  +  LI  L+G      Y  K+S    L P +    +     + +     + NE ++   +      P  +L  W +L  R ++A +    G++ +A    A+   K +K ++  +++S+   ++    + +E L++ L D CYK +    ++LL  +L  + G T +S+AY   +K F  H   Q +L  +W+GG+     V LK   V+L I  IFP L  T       R+I F+
Sbjct:    7 WISQNIKMKVCCWYIESSTAGGAARRVCECRHPRSEHANTALLKPT--LLGQKWEPAKHTANEPTNAFGDIQFTGLGQRL-GKFVRVGNDTEPSVLFKLMMEHWHLDVPNLLISVTGGAKNFHLKPQLRTIFRHGLNKTARSTGIQGAWIITGGSYAGVMKYVGESVRDFALASGSKEGKIVAIGIATWGIIHNKEHLIDAQGKFPAEYPMDEAGQGRLSCLDNNHSHFILVDNGTHGQYGVEIVLRARLEQYISTQ-----HTGSGGECR-SSKAVGVRGNCAA-RLW------DMCVRVRHC--------------------GKIVLIIMQAXSMVVREINSSVIFEKQNIYFDVLICLFFLGRIISRALLTGTYACAMVVVCISASRGEANKAQESCDHQLRLALAWNRVDIATSEIFTDDRKWQTGDLEQVMDAALLENRPEFISLFVEHGLILREYLTWARLESLYNGAPASSLLHILLRRISEGEKSPADPHRRWISTLPMAPKRMNHFSLYHISLLIRELLGDSTSMLYGNKMSRFSKLSPSSKNTGSTKGGTSLE-FKGQTYNEGQLYCPD------PERDLFIWAVLLNRRELANFFWSQGKDCMA---AALMASKLLKAMVQEEDDSDRTSDMLAQADNYEQLAIGLLDECYKDDELRAQKLLIRQLHSWGGATCLSMAYHANNKSFFSHSGVQALLTQIWWGGMS----VDLKTWRVILCI--IFPLLIYT-------RIITFR 702          

Query: 3568 NSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPVDFPEES-----------RLTPLA--WTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKK 4152
            NS N S  F  GR+++ +    + ++ + +    +  G  + +++ M+K I   + +L V + A+GV  QGI+   + +  +  I + +  +PY +++G+ +   +D   F   S           R   L   W   L   L++L A +++L+L+IA     +  +++++  ++ + RY ++ +Y SRP   PP I+   +Y+ +++
Sbjct:  817 NSINES-TFQAGRSVLCVDYMVFCLRLMHIFTVNKTLGPKIIIVKRMVKDIFFFLFLLGVWVVAYGVATQGILI--LNEQRLDWIFRGVVYQPYLLIFGQ-FPTRVDSTTFDTTSCTNNGINTSQPRCPVLGVDWLTILLTCLYLLFANILLLNLLIAMFNYTFQLVQDNTDTIWKFQRYELVNEYHSRPSLAPPLIVFSHLYLFVRR 1020          

Query:  217 KYNWIDDNILKLECNRFHPKSN--GYCACGRPAEEHINKNQFHNSSKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNN--IVALGISPWGIVQHRKHLLGKE--KICPYYSI-ANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYS---DEEGE----LPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRMEDG--CPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQILTLRQVGSLIEILMGGGYQHQYCQKLSPGKSLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVDNSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXXXXXXXXXXXXXXXDNE-SEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLR-EGKWVGLKVLIVLLSIIAIFPAL 2340
            K +WI  N  + EC RF PKS+    C CGRP E H   +Q    S   +E WN+   TT  PT+AYG ++F+G     +A Y+R+S+ T    V+ L+L+ WNL +PNLVIS+ GG  +F L+P+L+++F  GL+KAAKTTG W++T G +TGV KHVGEA+K +  + G++  +  +GI+ WGIV  +  L+ ++  K    YS+      + A+L+ +H++F L D+GT  K+G EI +R  +E   A   ++  +    G   VPVV +++EGG      ++EL+  +  VP VV +GSGRAA ++ F + ++   + +G+    + P   ++V   V   F    + A+  Y  +K  L+  ++I+VY + DG    DID+AIL ALL+ +  + +   QL L +AWNR D+A+S IF  + +W +  L  AM+ AL++D+ +F +L L+NG++M  FL +  L   Y    + G+ +   ++ K    ++ + + +  VG +IE LMG  ++  Y +       L    +    L +  + K+L +N        ++       PY ++  W +L  R ++A  +  +G E +A +LMA +LLK M      DN  ++   +L      FE  +V + D C+  N   ++ LL  EL  +S  T + LA   +S+ F+ H   Q +L  LW G +    +W   KVL+ L   + IFP +
Sbjct:   32 KKSWIARNFSRRECIRFVPKSHDVSRCKCGRPRERH---SQQALESGQGSEEWNVASCTTKHPTNAYGEIDFEGYGGQKRAPYLRMSHDTDANLVITLMLKRWNLEIPNLVISVTGGAKSFVLKPRLREMFRRGLIKAAKTTGAWIITGGTNTGVMKHVGEAVKEQQLMFGSDTQVNVIGIATWGIVDKQSDLISEKNGKYPALYSMEPTPGHQGAMLDPNHSHFFLVDDGTEGKYGVEIGMRSRIEE--AIMKVKTDSRSEAGSIGVPVVLLVLEGGPNTVATMYELIKKK--VPAVVIDGSGRAASVVGFAYNHTIKRNVDGQTINVIDPQYEDEVRAKVVEVFG--AKGADKTYSMIKDVLEDEKMISVYSL-DGEISQDIDLAILKALLKAN--RSSPVAQLNLALAWNRIDLAKSDIFTEEQQWTTETLSAAMLTALLDDKAEFAELFLQNGLSMREFLSLDILCKLYA--EVPGNTTIKPLLQKEMGKRQVKTIDMDVVGEVIEELMGDMFESYYRKDGHYFGELASYAEGL-VLKNRKSSKDLLAN--------INRIDPLPTPYLDVFLWAVLCNRRELARVLWEAGREPMAAALMASRLLKRMASRAQEDNTITDISSDLYDHARLFEERAVGVLDECFNENETLSQTLLVRELDHYSRMTALELAVSAESQDFIAHTSCQVLLTRLWMGTMAMNTRW--WKVLVCLYLPVLIFPII 732          

Query: 3334 ELYIYVHIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNI---LKNIYLKPYFMLYGEVYAAEIDPVDFPEESRLTPLA-WTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDY 4335
            E+ +Y  + T  ++  R+ A      I  K+ V+F   WNF D       +IA  +R+F                        S IF   R ++ L   +++++SL++    RL G  L MI+ M++ +   ++IL+V   A+G+    +M+      +  N    + ++   PY+ +YGE++  EI      E   + P   W  PL + ++M+   +++L+L+IA     + +++E S KV+ + RY ++ +Y SRP   PP ++L  I I ++ ++   + C                      H    + +K+ LS  E+E++ ++E +  E Y
Sbjct:  879 EIVLYFWVFTILIEEIRQLAAKPPKYIKDKVSVYFSDTWNFVDIFSLTVFIIAIILRFFTN----------------------SRIFTASRIILSLDIIFFIVRSLQIFSVNRLLGPKLVMIQKMMQDLAQFIIILAVFTIAYGIALHAVMFPSPGIYARNNTWVTITSVVQYPYWQMYGELFLDEIQGEKPKEFGEVDPDGRWLSPLLLAIYMVFTNILLLNLLIAIFNYTFERVQEDSDKVWKFQRYDLVQEYHSRPVFAPPLVLLGHILIFIRWVW---RMC-------------------RCGHPPRGSTMKIGLSPAEMEQMDNWEFQAAEMY 1172          

Query:  352 IKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKN--------EIHIKGNNIVALGISPWGIVQHRKHLLG-KEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRY-SDEEGELP--PDVRE--QVLKTVQRTFS-LVPREAEMLYKEMKLCLKRRELITVYRMEDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFY 1587
            +++  W    +T   PTDA+G LEFQG   P++A+Y+R+++ T P  VL LL  EW L +P L+IS+ GG  NF L PK+K+V  +GL+KAA+TTG WV+T G +TGV +HVGEA+K         ++    + +  +GI+ WGIV H++ L+  K ++ PY   ++   + A L+ +H++F+L DNGT  ++G EI  R SLE  +A++ +  + HG      VPVV +++EGG    R V E V+    VPVV+ EGSGRAAD+LAF HR+ +   GE+    DV E  Q+L  ++++F+   P +   +Y+ +  C+ +RE +T++ ++DG  ++D AIL ALL+    +L   DQL+L + W+R DIA+++IF    +W+ P+L+ AM++AL++DR++FV LLL+NGV+M  FL V RLE  Y
Sbjct:    1 VQDTKWVPTRHTVTLPTDAFGELEFQGAGQPSRAKYIRLAHDTDPELVLRLLCGEWALDLPKLLISVTGGAKNFILSPKIKRVLREGLLKAAQTTGAWVITGGTNTGVMRHVGEAVKGHTVMSRGEQLKNTAHQVHLIGIASWGIVDHKEMLVNPKVEVVPYQMTSSMQSRGACLDNNHSHFILVDNGTDGEYGGEISFRASLENLIASKKMAQKFHG------VPVVLLVLEGGPNTIRTVLESVSRCPAVPVVIAEGSGRAADILAFAHRFIAPSNGEMSGVADVVEHRQLLHKIEKSFAECSPEDRLSIYQNVLKCVAKREFVTIFCVDDGGLEVDKAILRALLKSQHSQLE--DQLSLALVWDRADIAKTEIFTEDQKWEVPMLETAMMEALLHDRVEFVDLLLDNGVSMANFLTVKRLEELY 419          

Query: 3634 WVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPVDFPEESRLTPLAW---------TVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDY 4335
            W+I+ L++    +  G Y+ MI  M   ++  ++I+ V + A+GV +Q I++    +     ++  I+ +PYF +YGE++   I+ VD+   SR T  +           V + M  ++L A +++L+L+IA   + + +++ +S +++ + R+ ++++Y  RP   PPFI++   + L K ++   + C             P         R      KLFL  +E  KL  FEE+C E +
Sbjct:  877 WIIRLLDIFSVSKDLGPYVVMIGRMTIDMMYFLVIMVVFLLAYGVAQQAILFPH--EKPSWELITKIFFRPYFQVYGELF---IEDVDYSSNSRETAFSTPKFDEYGGRLVTVIMAFYLLVANILLLNLLIAIFNNTFSEVQANSNQIWKFQRFSLVMEYRQRPRLVPPFILIAHAHGLAKAIW--KRAC-----------GAPA-------SRQADCKFKLFLGKEEYHKLMLFEEQCTETF 1094          

Query: 2068 KFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQT 2421
            +F  +++ L D CYK N    +RLL Y    + G T +SLA   + + F+ H C Q  L ++W G L+ G    LKVL+ +L     FP L   L         EF++++E+   P T
Sbjct:  594 EFYDIALGLLDECYKANDVLAQRLLIYHPVYWGGRTSLSLAVASRHEEFVAHSCCQKKLTEIWMGALKTGYNGSLKVLLGIL-----FPPLIFAL---------EFRSREEMQRVPTT 697          

Query:  202 STVSEKYNWIDDNILKLECNRF--HPKSNGYCACGRPAEEH------INKNQFHNSSKIK-----NEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQI-----LTLRQVGSLIEILMGGGYQHQYCQK---------LSPGK-SLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVDNS--SNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXX-XXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEYLN 2439
            + +  + +WI+    K EC       K    C CGR   +H      I+ +Q   + ++      +E W+I  +T   PTDA+GT+EFQGG H  KA YVR+SY T P  +LHL+ +EW L +P L+IS+ GGL NF+LQPKLK+VF  GL+KAA TTG W+ T G++TGV +HVG+ALK+        I  +GI+PWGIV++++ L+GK+ + PY +++N   K  VLN  H++F+LADNGT  K+GAE+ LRR LE++++ Q I    + R+G+  VPVVA++VEGG     +V E + D  PVPVVVC+GSGRA+D+LAF H+YS+E G +   +R+Q+L T+Q+TF+    +A+ L+  +  C+K++ELITV+RM  +G  DID+AILTALL+ +    +  DQL+L +AWNR DIARSQIF    +W    L+ AM+DAL+ DR+DFVKLL+ENGV++HRFL +SRLE  YN R        N++   V ++KK  +     ++L  +G +IE LMGG Y+  Y +K           P +   L +  M D +      +        E +I +D+   ++F +P+ EL+ W +L +R  MA++    GEE++AK+L+A         +  + D   +  +EL     +F  L+V L D  YK + +   +LL YEL+ +S  T + LA   + + F+ H C+Q +L D+W G LR  K  GLKV+              + LL   S   +EFK K E++  PQ  E YL 
Sbjct:   16 TEIKAQKSWIERAFSKRECVHIIVSAKDPHRCCCGRLIGQHVGLPPGISSSQNDKAERMAKNDSLSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSYDTKPDLLLHLMTKEWQLDLPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLVGKDVVRPYQTMSNPLSKLTVLNSLHSHFILADNGTTGKYGAEVRLRRQLEKHISLQKI----NTRIGQG-VPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGIINESLRDQLLVTIQKTFTYSRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGA--NASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSVHRFLTLSRLEELYNTR----HGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDMPIRRGRQKTTRKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSREFAQLAVELLDQSYKQDEQMAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVI--------------LGLLLPPSILSLEFKNKDEMSYMPQDQEAYLQ 768          

Query: 3202 KKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXK---WSVERIDYFELYIYVHIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDP-------------VDFPEESRLTPLAWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGN--VIKRTLQCMDQTQFQIGELHSRFNVMRV 4461
            +KIYEF+ API KF+ + ++++  ++L   +  +K   W   +    E  +  +I TN ++  R+   +    + QK+KV  +  WN  D       ++ FSV                     L    P     +GR +  +   YW I+ L++    +  G Y+ MI  M+  ++  V+I+ V++ +FGV RQ I+     +     + +NI+  PY+M+YGEV+A +IDP             V  P        AW VP  M  ++L A +++++L+IA   + + ++K  S +V+ + RY +I+ +  RP  PPP II   I ++LK +      C  + K    H++         D R++  GLKLF++ DE++K+HDFEE+C+E+Y++     D F   N   I+ T + ++    ++ E++ R + M+ 
Sbjct:  832 RKIYEFYNAPIVKFWFHTLAYVGYLMLFNYIVLVKMDLWPSPQ----EWIVIAYIFTNGIEKMREILMSEPGKLLQKVKVWLQEYWNITDL----MAILIFSV------------------GMVLRLQEPP-FMSYGRVIYCINIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILNPN--EDPSWMLARNIFFMPYWMIYGEVFADQIDPPCGQNITTDDGVVVALPA---CKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHITMVLKHL------CCRWRK----HDD---------DERDY--GLKLFITEDELKKVHDFEEQCIEEYFREKD--DRFHSSNDERIRVTSERVENMAMRLEEVNEREHFMKA 1214          

Query:  196 SLSTVSEKYNWIDDNILKLECNRF--HPKSNGYCACGRPAEEH------INKNQFHNSSKIK-----NEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQI-----LTLRQVGSLIEILMGGGYQHQYCQK---------LSPGK-SLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVDNS--SNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXX-XXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEYLN 2439
            S+  +  + +WI+    K EC       K    C CGR   +H      I+ +Q   + ++      +E W+I  +T   PTDA+GT+EFQGG H  KA YVR+SY T P  +LHL+ +EW L +P L+IS+ GGL NF+LQPKLK+VF  GL+KAA TTG W+ T G++TGV +HVG+ALK+        I  +GI+PWGIV++++ L+GK+ + PY +++N   K  VLN  H++F+LADNGT  K+GAE+ LRR LE++++ Q I    + R+G+  VPVVA++VEGG     +V E + D  PVPVVVC+GSGRA+D+LAF H+YS+E G +   +R+Q+L T+Q+TF+    +A+ L+  +  C+K++ELITV+RM  +G  DID+AILTALL+ +    +  DQL+L +AWNR DIARSQIF    +W    L+ AM+DAL+ DR+DFVKLL+ENGV++HRFL +SRLE  YN R        N++   V ++KK  +     ++L  +G +IE LMGG Y+  Y +K           P +   L +  M D +      +        E +I +D+   ++F +P+ EL+ W +L +R  MA++    GEE++AK+L+A         +  + D   +  +EL     +F  L+V L D  YK + +   +LL YEL+ +S  T + LA   + + F+ H C+Q +L D+W G LR  K  GLKV+              + LL   S   +EFK K E++  PQ  E YL 
Sbjct:   25 SVRLLKAQKSWIERAFSKRECVHIIVSAKDPHRCCCGRLIGQHVGLPPGISSSQNDKAERMAKNDSLSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSYDTKPDLLLHLMTKEWQLDLPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLVGKDVVRPYQTMSNPLSKLTVLNSLHSHFILADNGTTGKYGAEVRLRRQLEKHISLQKI----NTRIGQG-VPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGIINESLRDQLLVTIQKTFTYSRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGA--NASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSVHRFLTLSRLEELYNTR----HGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDMPIRRGRQKTTRKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSREFAQLAVELLDQSYKQDEQMAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVI--------------LGLLLPPSILSLEFKNKDEMSYMPQDQEAYLQ 779          

Query: 3202 KKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXK---WSVERIDYFELYIYVHIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEID--------------------------------PVDFPEESR-LTPL--------------------AWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGN--VIKRTLQCMDQTQFQIGELHSRFNVMRV 4461
            +KIYEF+ API KF+ + ++++  ++L   +  +K   W   +    E  +  +I TN ++  R+   +    + QK+KV  +  WN  D       ++ FSV                     L    P     +GR +  +   YW I+ L++    +  G Y+ MI  M+  ++  V+I+ V++ +FGV RQ I+     +     + +NI+  PY+M+YGEV+A +ID                                P  FP+ S+  TP                     AW VP  M  ++L A +++++L+IA   + + ++K  S +V+ + RY +I+ +  RP  PPP II   I ++LK +      C  + K    H++         D R++  GLKLF++ DE++K+HDFEE+C+E+Y++     D F   N   I+ T + ++    ++ E++ R + M+ 
Sbjct:  843 RKIYEFYNAPIVKFWFHTLAYVGYLMLFNYIVLVKMDLWPSPQ----EWIVIAYIFTNGIEKMREILMSEPGKLLQKVKVWLQEYWNITDL----MAILIFSV------------------GMVLRLQEPP-FMSYGRVIYCINIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILNPN--EDPSWMLARNIFFMPYWMIYGEVFADQIDHMHSRKFQQRLIEKVWLVENSLRTHGPWRSNGPSRFPQCSQNPTPCGQNITTDDGVVVALPACKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHITMVLKHL------CCRWRK----HDD---------DERDY--GLKLFITEDELKKVHDFEEQCIEEYFREKD--DRFHSSNDERIRVTSERVENMAMRLEEVNEREHFMKA 1268          

Query:  202 STVSEKYNWIDDNILKLECNRF--HPKSNGYCACGRPAEEH------INKNQFHNSSKIK-----NEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQI-----LTLRQVGSLIEILMGGGYQHQYCQK---------LSPGK-SLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVDNS--SNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXX-XXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEYLN 2439
            + +  + +WI+    K EC       K    C CGR   +H      I+ +Q   + ++      +E W+I  +T   PTDA+GT+EFQGG H  KA YVR+SY T P  +LHL+ +EW L +P L+IS+ GGL NF+LQPKLK+VF  GL+KAA TTG W+ T G++TGV +HVG+ALK+        I  +GI+PWGIV++++ L+GK+ + PY +++N   K  VLN  H++F+LADNGT  K+GAE+ LRR LE++++ Q I    + R+G+  VPVVA++VEGG     +V E + D  PVPVVVC+GSGRA+D+LAF H+YS+E G +   +R+Q+L T+Q+TF+    +A+ L+  +  C+K++ELITV+RM  +G  DID+AILTALL+ +    +  DQL+L +AWNR DIARSQIF    +W    L+ AM+DAL+ DR+DFVKLL+ENGV++HRFL +SRLE  YN R        N++   V ++KK  +     ++L  +G +IE LMGG Y+  Y +K           P +   L +  M D +      +        E +I +D+   ++F +P+ EL+ W +L +R  MA++    GEE++AK+L+A         +  + D   +  +EL     +F  L+V L D  YK + +   +LL YEL+ +S  T + LA   + + F+ H C+Q +L D+W G LR  K  GLKV+              + LL   S   +EFK K E++  PQ  E YL 
Sbjct:   16 TEIKAQKSWIERAFSKRECVHIIVSAKDPHRCCCGRLIGQHVGLPPGISSSQNDKAERMAKNDSLSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSYDTKPDLLLHLMTKEWQLDLPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLVGKDVVRPYQTMSNPLSKLTVLNSLHSHFILADNGTTGKYGAEVRLRRQLEKHISLQKI----NTRIGQG-VPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGIINESLRDQLLVTIQKTFTYSRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGA--NASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSVHRFLTLSRLEELYNTR----HGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDMPIRRGRQKTTRKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSREFAQLAVELLDQSYKQDEQMAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVI--------------LGLLLPPSILSLEFKNKDEMSYMPQDQEAYLQ 768          

Query: 3202 KKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXK---WSVERIDYFELYIYVHIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEID--------------------------------PVDFPEESR-LTPL--------------------AWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGN--VIKRTLQCMDQTQFQIGELHSRFNVMRV 4461
            +KIYEF+ API KF+ + ++++  ++L   +  +K   W   +    E  +  +I TN ++  R+   +    + QK+KV  +  WN  D       ++ FSV                     L    P     +GR +  +   YW I+ L++    +  G Y+ MI  M+  ++  V+I+ V++ +FGV RQ I+     +     + +NI+  PY+M+YGEV+A +ID                                P  FP+ S+  TP                     AW VP  M  ++L A +++++L+IA   + + ++K  S +V+ + RY +I+ +  RP  PPP II   I ++LK +      C  + K    H++         D R++  GLKLF++ DE++K+HDFEE+C+E+Y++     D F   N   I+ T + ++    ++ E++ R + M+ 
Sbjct:  832 RKIYEFYNAPIVKFWFHTLAYVGYLMLFNYIVLVKMDLWPSPQ----EWIVIAYIFTNGIEKMREILMSEPGKLLQKVKVWLQEYWNITDL----MAILIFSV------------------GMVLRLQEPP-FMSYGRVIYCINIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILNPN--EDPSWMLARNIFFMPYWMIYGEVFADQIDHMHSRKFQQRLIEKVWLVENSLRTHGPWRSNGPSRFPQCSQNPTPCGQNITTDDGVVVALPACKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHITMVLKHL------CCRWRK----HDD---------DERDY--GLKLFITEDELKKVHDFEEQCIEEYFREKD--DRFHSSNDERIRVTSERVENMAMRLEEVNEREHFMKA 1257          

Query:  196 SLSTVSEKYNWIDDNILKLECNRF--HPKSNGYCACGRPAEEH------INKNQFHNSSKIK-----NEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQI-----LTLRQVGSLIEILMGGGYQHQYCQK---------LSPGKSLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVD----NSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXX-XXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEYLN 2439
            S+  +  + +WI+    K EC       K    C CGR   +H      I+ +Q   + ++      +E W+I  +T   PTDA+GT+EFQGG H  KA YVR+SY T P  +LHL+ +EW L +P L+IS+ GGL NF+LQPKLK+VF  GL+KAA TTG W+ T G++TGV +HVG+ALK+        I  +GI+PWGIV++++ L+GK+ + PY +++N   K  VLN  H++F+LADNGT  K+GAE+ LRR LE++++ Q I    + R+G+  VPVVA++VEGG     +V E + D  PVPVVVC+GSGRA+D+LAF H+YS+E G +   +R+Q+L T+Q+TF+    +A+ L+  +  C+K++ELITV+RM  +G  DID+AILTALL+ +    +  DQL+L +AWNR DIARSQIF    +W    L+ AM+DAL+ DR+DFVKLL+ENGV++HRFL +SRLE  YN R        N++   V ++KK  +     ++L  +G +IE LMGG Y+  Y +K           P +  +P+                 +    E E+ +D      ++F +P+ EL+ W +L +R  MA++    GEE++AK+L+A         +  + D   +  +EL     +F  L+V L D  YK + +   +LL YEL+ +S  T + LA   + + F+ H C+Q +L D+W G LR  K  GLKV+              + LL   S   +EFK K E++  PQ  E YL 
Sbjct:   36 SVRLLKAQKSWIERAFSKRECVHIIVSAKDPHRCCCGRLIGQHVGLPPGISSSQNDKAERMAKNDSLSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSYDTKPDLLLHLMTKEWQLDLPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLVGKDVVRPYQTMSNPLSKLTVLNSLHSHFILADNGTTGKYGAEVRLRRQLEKHISLQKI----NTRIGQG-VPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGIINESLRDQLLVTIQKTFTYSRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGA--NASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSVHRFLTLSRLEELYNTR----HGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDMPI-----------RRGRQKTTRKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSREFAQLAVELLDQSYKQDEQMAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVI--------------LGLLLPPSILSLEFKNKDEMSYMPQDQEAYLQ 780          

Query: 3202 KKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXK---WSVERIDYFELYIYVHIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDP-------------VDFPEESRLTPLAWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGN--VIKRTLQCMDQTQFQIGELHSRFNVMRV 4461
            +KIYEF+ API KF+ + ++++  ++L   +  +K   W   +    E  +  +I TN ++  R+   +    + QK+KV  +  WN  D       ++ FSV                     L    P     +GR +  +   YW I+ L++    +  G Y+ MI  M+  ++  V+I+ V++ +FGV RQ I+     +     + +NI+  PY+M+YGEV+A +IDP             V  P        AW VP  M  ++L A +++++L+IA   + + ++K  S +V+ + RY +I+ +  RP  PPP II   I ++LK +      C  + K    H++         D R++  GLKLF++ DE++K+HDFEE+C+E+Y++     D F   N   I+ T + ++    ++ E++ R + M+ 
Sbjct:  832 RKIYEFYNAPIVKFWFHTLAYVGYLMLFNYIVLVKMDLWPSPQ----EWIVIAYIFTNGIEKMREILMSEPGKLLQKVKVWLQEYWNITDL----MAILIFSV------------------GMVLRLQEPP-FMSYGRVIYCINIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILNPN--EDPSWMLARNIFFMPYWMIYGEVFADQIDPPCGQNITTDDGVVVALPA---CKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHITMVLKHL------CCRWRK----HDD---------DERDY--GLKLFITEDELKKVHDFEEQCIEEYFREKD--DRFHSSNDERIRVTSERVENMAMRLEEVNEREHFMKA 1214          

Query:  223 NWIDDNILKLECNRF--HPKSNGYCACGRPAEEH------INKNQFHNSSKIK-----NEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRM-EDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQI-----LTLRQVGSLIEILMGGGYQHQYCQK---------LSPGK-SLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVDNS--SNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXX-XXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEYLN 2439
            +WI+    K EC       K    C CGR   +H      I+ +Q   + ++      +E W+I  +T   PTDA+GT+EFQGG H  KA YVR+SY T P  +LHL+ +EW L +P L+IS+ GGL NF+LQPKLK+VF  GL+KAA TTG W+ T G++TGV +HVG+ALK+        I  +GI+PWGIV++++ L+GK+ + PY +++N   K  VLN  H++F+LADNGT  K+GAE+ LRR LE++++ Q I    + R+G+  VPVVA++VEGG     +V E + D  PVPVVVC+GSGRA+D+LAF H+YS+E G +   +R+Q+L T+Q+TF+    +A+ L+  +  C+K++ELITV+RM  +G  DID+AILTALL+ +    +  DQL+L +AWNR DIARSQIF    +W    L+ AM+DAL+ DR+DFVKLL+ENGV++HRFL +SRLE  YN R        N++   V ++KK  +     ++L  +G +IE LMGG Y+  Y +K           P +   L +  M D +      +        E +I +D+   ++F +P+ EL+ W +L +R  MA++    GEE++AK+L+A         +  + D   +  +EL     +F  L+V L D  YK + +   +LL YEL+ +S  T + LA   + + F+ H C+Q +L D+W G LR  K  GLKV+              + LL   S   +EFK K E++  PQ  E YL 
Sbjct:   72 SWIERAFSKRECVHIIVSAKDPHRCCCGRLIGQHVGLPPGISSSQNDKAERMAKNDSLSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSYDTKPDLLLHLMTKEWQLDLPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLVGKDVVRPYQTMSNPLSKLTVLNSLHSHFILADNGTTGKYGAEVRLRRQLEKHISLQKI----NTRIGQG-VPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGIINESLRDQLLVTIQKTFTYSRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGA--NASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSVHRFLTLSRLEELYNTR----HGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDMPIRRGRQKTTRKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSREFAQLAVELLDQSYKQDEQMAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVI--------------LGLLLPPSILSLEFKNKDEMSYMPQDQEAYLQ 817          

Query: 3202 KKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXK---WSVERIDYFELYIYVHIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEID--------------------------------PVDFPEESR-LTPL--------------------AWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGN--VIKRTLQCMDQTQFQIGELHSRFNVMRV 4461
            +KIYEF+ API KF+ + ++++  ++L   +  +K   W   +    E  +  +I TN ++  R+   +    + QK+KV  +  WN  D       ++ FSV                     L    P     +GR +  +   YW I+ L++    +  G Y+ MI  M+  ++  V+I+ V++ +FGV RQ I+     +     + +NI+  PY+M+YGEV+A +ID                                P  FP+ S+  TP                     AW VP  M  ++L A +++++L+IA   + + ++K  S +V+ + RY +I+ +  RP  PPP II   I ++LK +      C  + K    H++         D R++  GLKLF++ DE++K+HDFEE+C+E+Y++     D F   N   I+ T + ++    ++ E++ R + M+ 
Sbjct:  881 RKIYEFYNAPIVKFWFHTLAYVGYLMLFNYIVLVKMDLWPSPQ----EWIVIAYIFTNGIEKMREILMSEPGKLLQKVKVWLQEYWNITDL----MAILIFSV------------------GMVLRLQEPP-FMSYGRVIYCINIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILNPN--EDPSWMLARNIFFMPYWMIYGEVFADQIDHMHSRKFQQRLIEKVWLVENSLRTHGPWRSNGPSRFPQCSQNPTPCGQNITTDDGVVVALPACKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHITMVLKHL------CCRWRK----HDD---------DERDY--GLKLFITEDELKKVHDFEEQCIEEYFREKD--DRFHSSNDERIRVTSERVENMAMRLEEVNEREHFMKA 1306          

Query:  154 HSGIVANPSLKSNRSLSTVSEKYNWIDDNILKLECNRFHPKSNGYCACGRPAEEHINKNQFHNSSKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRMEDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQILTLRQVGSLIEILMGGGYQHQYCQKLSPGKSLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVDNSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXXXXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEYLNXXXXXXXXXXXXXXXETTDDAEAFGKSKQDENNHSSLYKSKSTTSDLKEIKRLHRASSLQKESLYNELYMKCSDFAKSDPTLNQDXXXXXXXXXXXXXXGETDETKYETTGAFDNHKSKRRIYQIGGDINPEFYFKEENLDYANNSHLNFENRISKEKIHRKKREMPNKPFKDDFDIDTRKKLHSKHNLHVSPTVSSFSFHQPLNILQPTLTDMSHRASVTFNNLSFTKCAPDALFEFCQENPQISPGTQLSCRKKIYEFFYAPITKFYXXXXXXXXXXXXXXXXXXXKWSVERIDYFELYIYVHIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPVDFPEESRLTPLAWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGMNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGNVIKRTLQCMDQTQFQIGELHSRFNVMRVXXXXXXXXXXXXXXXXXCQSAALLEKISEFENKLINTPGHISFFNCKNNTNSVCDGSEKAEDNNKNNSMLNAERKNVSKLISESAHCDSPFEKTVSRNHIFGFPNYKQKSIPKSYQSTYPITDKYTIPLRRDYXXXXXXXXXXXXXXXRETPPASPTSSMIDLSHPGKSKRSNRLMKSKAKRNKLLSNKEIIIGDKEEELRQAEKIEREEMTSVIVQRLRQLSHKQTYSSTEEIDENITEVVQEIVASKSEDVNSTNTFTKXXXXXXXXXXXXAKRFTRQYSTPIVVTDDLVIFKLTSDLD 5364
            HSGIVANPSLKSNRSLSTVSEKYNWIDDNILKLECNRFHPKSNGYCACGRPAEEHINKNQFHNSSKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRMEDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQILTLRQVGSLIEILMGGGYQHQYCQKLSPGKSLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVDNSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAKSLMAMKLLKGMKKLLDMDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEYLNDSSSDSSSDSSSSDDETTDDAEAFGKSKQDENNHSSLYKSKSTTSDLKEIKRLHRASSLQKESLYNELYMKCSDFAKSDPTLNQDHINENIVNHVVINIGETDETKYETTGAFDNHKSKRRIYQIGGDINPEFYFKEENLDYANNSHLNFENRISKEKIHRKKREMPNKPFKDDFDIDTRKKLHSKHNLHVSPTVSSFSFHQPLNILQPTLTDMSHRASVTFNNLSFTKCAPDALFEFCQENPQISPGTQLSCRKKIYEFFYAPITKFYLNVISHILLIILLIRLAFIKWSVERIDYFELYIYVHIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPVDFPEESRLTPLAWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPG+NDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGNVIKRTLQCMDQTQFQIGELHSRFNVMRVNLQCTNNNLNDLNINYNCQSAALLEKISEFENKLINTPGHISFFNCKNNTNSVCDGSEKAEDNNKNNSMLNAERKNVSKLISESAHCDSPFEKTVSRNHIFGFPNYKQKSIPKSYQSTYPITDKYTIPLRRDYTTICDDIIISDWISTRETPPASPTSSMIDLSHPGKSKRSNRLMKSKAKRNKLLSNKEIIIGDKEEELRQAEKIEREEMTSVIVQRLRQLSHKQTYSSTEEIDENITEVVQEIVASKSEDVNSTNTFTKSNISSSLINFSNAKRFTRQYSTPIVVTDDLVIFKLTSDLD
Sbjct:    8 HSGIVANPSLKSNRSLSTVSEKYNWIDDNILKLECNRFHPKSNGYCACGRPAEEHINKNQFHNSSKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRMEDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQILTLRQVGSLIEILMGGGYQHQYCQKLSPGKSLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVDNSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAKSLMAMKLLKGMKKLLDMDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEYLNDSSSDSSSDSSSSDDETTDDAEAFGKSKQDENNHSSLYKSKSTTSDLKEIKRLHRASSLQKESLYNELYMKCSDFAKSDPTLNQDHINENIVNHVVINIGETDETKYETTGAFDNHKSKRRIYQIGGDINPEFYFKEENLDYANNSHLNFENRISKEKIHRKKREMPNKPFKDDFDIDTRKKLHSKHNLHVSPTVSSFSFHQPLNILQPTLTDMSHRASVTFNNLSFTKCAPDALFEFCQENPQISPGTQLSCRKKIYEFFYAPITKFYLNVISHILLIILLIRLAFIKWSVERIDYFELYIYVHIITNFLDHFRKFANTAGINIAQKMKVHFESLWNFFDFSWGFYCLIAFSVRYFATYQFQQIKHQTDRNSTTLNSNNPSEIFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEIDPVDFPEESRLTPLAWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFIILVWIYILLKKMYFSMKFCFYFFKRKYTHNNKPGLNDNNFDHRNHSAGLKLFLSVDEIEKLHDFEEECVEDYWQHAKFHDEFEPGNVIKRTLQCMDQTQFQIGELHSRFNVMRVNLQCTNNNLNDLNINYNCQSAALLEKISEFENKLINTPGHISFFNCKNNTNSVCDGSEKAEDNNKNNSMLNAERKNVSKLISESAHCDSPFEKTVSRNHIFGFPNYKQKSIPKSYQSTYPITDKYTIPLRRDYTTICDDIIISDWISTRETPPASPTSSMIDLSHPGKSKRSNRLMKSKAKRNKLLSNKEIIIGDKEEELRQAEKIEREEMTSVIVQRLRQLSHKQTYSSTEEIDENITEVVQEIVASKSEDVNSTNTFTKSNISSSLINFSNAKRFTRQYSTPIVVTDDLVIFKLTSDLD 1744          

Query:  154 HSGIVANPSLKSNRSLSTVSEKYNWIDDNILKLECNRFHPKSNGYCACGRPAEEHINKNQFHNSSKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRMEDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQILTLRQVGSLIEILMGGGYQHQYCQKLSPGKSLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVDNSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXXXXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEYLNXXXXXXXXXXXXXXXETTDDAEAFGKSKQDENNHSSLYKSKSTTSDLKEIKRLHRASSLQKESLYNELYMKCSDFAKSDPTLNQDXXXXXXXXXXXXXXGETDETKYETT 2769
            HSGIVANPSLKSNRSLSTVSEKYNWIDDNILKLECNRFHPKSNGYCACGRPAEEHINKNQFHNSSKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRMEDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQILTLRQVGSLIEILMGGGYQHQYCQKLSPGKSLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVDNSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAKSLMAMKLLKGMKKLLDMDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEYLNDSSSDSSSDSSSSDDETTDDAEAFGKSKQDENNHSSLYKSKSTTSDLKEIKRLHRASSLQKESLYNELYMKCSDFAKSDPTLNQDHINENIVNHVVINIGETDETKYETT
Sbjct:    8 HSGIVANPSLKSNRSLSTVSEKYNWIDDNILKLECNRFHPKSNGYCACGRPAEEHINKNQFHNSSKIKNEGWNIIHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHIKGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQKQAVLNQHHNYFLLADNGTVDKFGAEIVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAFMHRYSDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRMEDGCPDIDVAILTALLQESLPKLTKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQILTLRQVGSLIEILMGGGYQHQYCQKLSPGKSLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVDNSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAKSLMAMKLLKGMKKLLDMDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIFPALPITLLTLKSNRLIEFKTKQELALQPQTLEEYLNDSSSDSSSDSSSSDDETTDDAEAFGKSKQDENNHSSLYKSKSTTSDLKEIKRLHRASSLQKESLYNELYMKCSDFAKSDPTLNQDHINENIVNHVVINIGETDETKYETT 879          

Query:  289 CACGRPAEEHINKNQFHNSSKIKNEGWNIIHNTTPFPTDAYGTLEFQGG--PHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKN---EIH--IKGNN-IVALGISPWGIVQHRKHLLGKEKICPYYSIANKN--QKQAVLNQHHNYFLLADNGTVDKFGAEIV--LRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLL--AF--MHRY------SDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRMEDGCPDIDVAILTALLQE----SLPKL-TKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQILTLRQVGSLIEILMGGGYQHQYCQKLSPGKSLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVDNSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXXXXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGL 2268
            C CG    EH      +N    K   W+I       PT+++G +EF G    +     +VR+S+     DV+ L+   WN+ +  L IS++GG  NF ++ K K +F+ GL+KA KTT   ++T+GL+ G+T+ VG+A++N   +++   KGNN +  LGI+PWG V+++K L   +     Y ++N+    +   LN++H ++L  D      +        R +LE+ L+    R +N     K  +PVV +L+EG    F    + + +   VP+V+C G+GRA+DLL  AF  M +Y       D    LP   R  + K +       P +       ++  + +  LIT++ +++   D+++AIL +L++     S  KL T + QL+L + WNR DIA+ +IF              + +++IN + +FV+L L+NG  M+ FL  + LE  Y   C +   SFN   +    L +     L  V  L+  +   GY    C              MCD                              +P+ EL  W++L   ++ A Y     EES+  +L+A K+ K + ++  +D  +  +E L  W + FE L++ L + C+  + E    ++  E   + G+T + +AY  + + F+  +  QN L+  W  G 
Sbjct:   79 CLCGELKSEHKKDKIPYN----KVNDWSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQ---RTKN-----KEPIPVVLLLIEGEYDVFFEASKRIKEN--VPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKED-HDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYE-DCPR---SFNLKRTIFHFLGRNFSNGLGDVKDLLTKIF--GYYEDQCA-------------MCD--------------------------EEIIHPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSPLD--TSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGF 703          

Query:  289 CACGRPAEEHINKNQFHNSSKIKNEGWNIIHNTTPFPTDAYGTLEFQGG--PHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKN---EIH--IKGNN-IVALGISPWGIVQHRKHLLGKEKICPYYSIANKN--QKQAVLNQHHNYFLLADNGTVDKFGAEIV--LRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLL--AF--MHRY------SDEEGELPPDVREQVLKTVQRTFSLVPREAEMLYKEMKLCLKRRELITVYRMEDGCPDIDVAILTALLQE----SLPKL-TKADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQILTLRQVGSLIEILMGGGYQHQYCQKLSPGKSLLPVTDMCDTLSSVDNFKNLYSNSLNENEIGVDNSSNFRYPYTELLQWTILTRRYDMAMYMVMSGEESIAXXXXXXXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGL 2268
            C CG    EH      +N    K   W+I       PT+++G +EF G    +     +VR+S+     DV+ L+   WN+ +  L IS++GG  NF ++ K K +F+ GL+KA KTT   ++T+GL+ G+T+ VG+A++N   +++   KGNN +  LGI+PWG V+++K L   +     Y ++N+    +   LN++H ++L  D      +        R +LE+ L+    R +N     K  +PVV +L+EG    F    + + +   VP+V+C G+GRA+DLL  AF  M +Y       D    LP   R  + K +       P +       ++  + +  LIT++ +++   D+++AIL +L++     S  KL T + QL+L + WNR DIA+ +IF              + +++IN + +FV+L L+NG  M+ FL  + LE  Y   C +   SFN   +    L +     L  V  L+  +   GY    C              MCD                              +P+ EL  W++L   ++ A Y     EES+  +L+A K+ K + ++  +D  +  +E L  W + FE L++ L + C+  + E    ++  E   + G+T + +AY  + + F+  +  QN L+  W  G 
Sbjct:   79 CLCGELKSEHKKDKIPYN----KVNDWSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQ---RTKN-----KEPIPVVLLLIEGEYDVFFEASKRIKEN--VPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKED-HDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYE-DCPR---SFNLKRTIFHFLGRNFSNGLGDVKDLLTKIF--GYYEDQCA-------------MCD--------------------------EEIIHPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSPLD--TSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGF 703          

Query: 3589 IFLWGRNLIILGSAYWVIKSLELMQNWRLFGAYLEMIRIMIKQIVPPVLILSVIMTAFGVVRQGIMYQGVVDLSIGNILKNIYLKPYFMLYGEVYAAEI--------DPVDFPEESRLTPLAWTVPLAMVLFMLSAVVVILSLIIAGVTDIYGKMKESSVKVYMYLRYPIIIDYESRPFAPPPFII 4122
            I+   + +  L   Y+ ++ L L+   +  G  + MI  M+ Q++  ++I+ +I+ A+G+  QG  Y    D S+ N L NI   PY+ ++GE+   ++           ++   +    L + VP+   +++  A +++L+++ A    I+ ++  +S++++ +  + ++++Y ++P  P PF I
Sbjct:  800 IYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKMLYQLMFYIIIMLIILLAYGITMQG-AYFPQRDFSL-NTLPNIMDYPYWAIFGEITLNQLVYLPWCDDKTTNYNISNECPELNYFVPVLTAIYIFIAAILLLNILTAVFNYIFQRIHRNSIEIWKFTMFSLVMEYYTKPLFPLPFSI 983          

Query:  376 IHNTTPFPTDAYGTLEFQGGPHPTKARYVRISYRTTPTDVLHLLLREWNLRVPNLVISIIGGLANFDLQPKLKKVFFDGLVKAAKTTGTWVVTTGLDTGVTKHVGEALKNEIHI-KGNNIVALGISPWGIVQHRKHLLGKEKICPYYSIANKNQ--------------KQAVLNQHHNYFLLADNGTVDKFGAE--IVLRRSLERYLATQPIRMRNHGRLGKSRVPVVAVLVEGGMQAFRLVFELVTDEYPVPVVVCEGSGRAADLLAF----MHRYSDEEG----ELPPDVREQVLKTVQRT--FSLVPREAEMLYKEMKLCLKRREL---ITVYRMEDGCPDIDVAILTALLQESLPKLTK----ADQLTLTMAWNRPDIARSQIFGIQTEWQSPVLDNAMIDALINDRLDFVKLLLENGVNMHRFLKVSRLEYFYNIRCLKGDFSFNSMISKVCNLKKKQILT----LRQVGSLIEILMGGGYQHQYCQK 1740
            I      PT+A+G +EF G      A++VR+   T   ++  +L  +W L  P LVISI GG  +F+ + KLK +   GL KAA++ G W++T GL+ G+ K  GEA+++      GN +VA+GI+PW +V     L        Y +I    +              K+  L+ +H+YF L D     K  +E  +  R   E  ++    +  ++     +RVP+  ++V G +   R VF  +  E   PVVVC+GS  AAD+LA       ++  EEG    E+ P   E  L+++ R   F + P   +   + ++L     EL   ++V+ ME+   D+D  I+++LL  +   LT+     +QL +T+  NR DIA+ +IF    +W+   L++ M +AL++DR DFVKL LE G ++  FL V  LE  Y  + LK   S   +  ++ +  K   L     LR+VG +I+IL+G  Y   Y  K
Sbjct:  288 IRKNYTLPTNAFGEIEFTGLNQS--AKFVRLLNSTPEVNIQTILQIKWELYHPTLVISIFGG--DFEKKRKLKMIIKKGLWKAAESAGCWIITEGLNMGIMKLAGEAVRDYTDAYGGNKMVAIGIAPWNVVAKNDVLENSLYQGTYPAIYQSEEESETNDDGMVKDRNKEKSLDTNHSYFFLYDCPASSKEISEPDVQFRSRFEHSISFWKSQTSSYETSNDTRVPICGLVVGGDILTLRQVFNSII-ENKCPVVVCQGSSGAADVLALAIDAFQKFDLEEGSEEFEIVP--LEARLESIIRECLFKINPEIKDFKKESVQLKQIVTELGYLVSVFDMEEDW-DLDGYIISSLLNSAASDLTQNQLNLEQLEITLTLNRADIAKEKIFLENKKWKKGDLNDYMFNALMSDRHDFVKLFLEQGFSLEEFLTVYILEKLYTDQ-LKNLNSRIEIFHRLWDNHKTHRLVKNVKLREVGKVIKILVGDFYHPLYLSK 771          

Query: 1879 PYTELLQWTILTRRYDMA-MYMVMSGEESIAXXXXXXXXXXXXXXXXXXDNESEYLEELKLWGNKFEVLSVSLQDHCYKHNPEETKRLLCYELQQFSGHTGISLAYLCQSKPFLGHVCTQNILNDLWYGGLREGKWVGLKVLIVLLSIIAIF 2331
            P  EL+ W++L  +  MA ++  M  E+     L +M L     K  D  ++ +Y    K +   FE  +  + + CY  + +  + L+  EL+ +   + I LA   QS  F+ H C Q+ L   WYG L       + +  V L II  F
Sbjct:  964 PARELMIWSLLVGKLQMAELFWAMEKEQIAGALLASMLLTSLANKSDDFTDKEDY----KTYSKHFESQAEGVLNECYIEDEKRAQLLINKELKYYGQSSVILLAAQGQSIKFMAHPCCQDFLTSTWYGNLSSKNSAMMLLASVGLGIIMPF 1111