Intersectin-1

Query: 2375 GEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQTIDTISSDYYTALSLENSNSPTM-------------TYDDIGRNLNDFDTDSGI----TDPELATPAEIGENAAY--SNYCTLAXXXXXXXXXXXXXXXLSK----AKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNE-GWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLL--VTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLI-MAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIR--RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFF 4957
            G    ALYP+ +     L     D+I +++    WW G ++G  + G FP  YVK L    +  + ++D+ SS+  +  SL+   SP               TY+   +    F     I     D +  T   +G+ A    SNY  L               SL K    A+++ +Y+A   ++L+  PGQ + I   +   W++ +L   G   + GW P                      + Y + L+  G+  ++         +    ++I MY Y+AQN DEL+F K  I+ +++K++P+WW+G       +GLFP NYV+      + D         +PS +              W  D  ++   +LT  E++RQ YI ELI TE+ Y  DLQ V  +F +P+ +S LLT +E+  IF+NW +LI  +     AL++RK  SG K P++ +GDIL +  P+   Y+RFCS Q    AL+++K   +  FKEF ++   + RCK MP+SS+ LKPMQR+T+Y LI++NIL+NT + HPD   ++ A+  A  LC  VNEG+REKENS+RLEWIQ HVQC+GL+E+L FNS TN LG RK ++SG LYKAKS KEL GFLFNDFLLL  +T    ++G   VF    S    +Q+KMYK PI LN VL+ +   PS                      IF I      + L+A S+N+R  WV+++ AAS  YIETE   RE +  +R  R+ G+GRL+V V+EG  LK   +   K++ YCE ++G+Q   TK +  T NPKWN + QF I+++E +VLC++ ++++ F+P+DFLGRTE+ + DIK+ +  +KGP+ + L L  V +GE++V+LDL  F
Sbjct:  910 GLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDMWWFGEVQG--QKGWFPKSYVK-LISGPIRKSTSMDSGSSE--SPASLKRVASPAAKPVVSGEEFIAMYTYESSEQGDLTFQQGDVILVTKKDGDWWT-GTVGDKAGVFPSNYVRL--KDSEGSGTAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFP----------------------ANYVKLLSP-GTSKITPTEPPKSTALAAVCQVIGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGE--VNGQVGLFPSNYVK-----LTTD--------MDPSQQ--------------WCSD--LHLLDMLTPTERKRQGYIHELIVTEENYVNDLQLVTEIFQKPLMESELLTEKEVAMIFVNWKELIMCNIKLLKALRVRKKMSGEKMPVKMIGDILSAQLPHMQPYIRFCSRQLNGAALIQQKTDEAPDFKEFVKRLAMDPRCKGMPLSSFILKPMQRVTRYPLIIKNILENTPENHPDHSHLKHALEKAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQITKPLGSSGTDKVF----SPKSNLQYKMYKTPIFLNEVLVKLPTDPSGDE------------------PIFHISHIDRVYTLRAESINERTAWVQKIKAASELYIETEKKKREKAYLVRSQRATGIGRLMVNVVEGIELKPCRS-HGKSNPYCEVTMGSQCHITKTIQDTLNPKWNSNCQFFIRDLEQEVLCITVFERDQFSPDDFLGRTEIRVADIKKDQ-GSKGPVTKCLLLHEVPTGEIVVRLDLQLF 1713          

Query:   74 GNQSQWSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPP------DSFPFSDLGANEIFSSKAAPSYNEV----MAKDKADRQSFREKPPIPQDIQSTFPPLP---------------KRTSPQT---------------------DWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSMVTISNNNKSLPNSHTEHEWTATSESRPGTLKACPASPQIIQETSMNTAQWNKPLPVTPEIEIQSQIHQ-KLEKEKQRLIDLEETRLQQAVXXXXXXXXXXXXXXDRQE 1153
            G+   W+I+ EE ++H  QF  L P+ GFI+G QA+ +  +S L   +L +IW+LAD++ DGRM   EFSIAM LIK KL+G +LP+ LP  M   P       +F    + +    ++ A      +    M+            PP+         PLP                R+ P +                     +W + Q+ R +YR  FN  D+   G L+G +A+ +L+QS L  + LA IWNLSDID DGKLT EEF +AM+L++ A +G+ LP  LP   +PPS   + + +     S T  +            +  P  P +  E      Q  K LPVT E + +    +  LE EK+R   LE+ R +Q    +    E  +K ++RQE
Sbjct:   10 GSLDIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQGYQLPSALPPVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLANGAPPVIQPLPAFAHPAATLPKSSSFSRSGPGSQLNTKLQKAQSFDVASVPPVAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGISVISSTSVD------------QRLPEEPVLEDEQQ----QLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQE 400          

Query: 1733 ESYQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNVFDQTLPDGATIKKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMS-THWWKGHIRGARENGMFPSHYVKKLTKQD 2557
            E + A+Y +   +  +LTF+ GD+ILV           W  G   +    G+FP+ YV+              DSE S          T     ++ K P    V A +          P+QL+   GQ I + ++  G WW+GE+    +  G    +GWFP  YV+ +      +  TE     +    AA   + G                     +Y Y +    +L    G II +++     WWKG + G  + G+FPS+YVK  T  D
Sbjct: 1000 EEFIAMYTYESSEQGDLTFQQGDVILV-----TKKDGDWWTG--TVGDKAGVFPSNYVR------------LKDSEGSG---------TAGKTGSLGKKPEIAQVIASY------TATGPEQLTLAPGQLILIRKKNPGGWWEGEL----QARGKKRQIGWFPANYVKLLSPGTSKITPTEPPKSTA---LAAVCQVIG---------------------MYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNG--QVGLFPSNYVKLTTDMD 1211          

Query: 2045 VEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVK--------------KLTKQDLEHAQTIDTISSDYYTALSLENSNSPTMTYDDIGRNLNDFDTDSGITDPELATPAEIGENAAY-SNYCTLAXXXXXXXXXXXXXXXLSKAKIVRA-----YSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTN 2956
             +A++PW    ++     L+FN    I V+E++   WW GE+             GWFP+ YV+ +        S +S    S  +          P+            GE  +A+Y YES+  GDLT + GD+I +      WW G +    + G+FPS+YV+               L K+  E AQ I + ++     L+L       +   + G          G  + EL    +  +   + +NY  L      + +      S + A + +      Y+A + DEL+   GQ +N+++  D DW+K +  +NG   
Sbjct:  913 AQALYPWRAKKDN----HLNFNKNDVITVLEQQDM-WWFGEVQGQK---------GWFPKSYVKLISGPIRKSTSMDSGSSESPASLKRVASPAAKPVVS----------GEEFIAMYTYESSEQGDLTFQQGDVILVTKKDGDWWTGTV--GDKAGVFPSNYVRLKDSEGSGTAGKTGSLGKKP-EIAQVIASYTATGPEQLTLAPGQLILIRKKNPG----------GWWEGELQARGKKRQIGWFPANYVKLLSPGTSKITPTEPPKSTALAAVCQVIGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGE--VNGQVG 1197          

Query: 2375 GEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQTIDTISSDYYTALSLENSNSPTM-------------TYDDIGRNLNDFDTDSGI----TDPELATPAEIGENAAY--SNYCTLAXXXXXXXXXXXXXXXLSK----AKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNE-GWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLL--VTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLI-MAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIR--RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFF 4957
            G    ALYP+ +     L     D+I +++    WW G ++G  + G FP  YVK L    +  + ++D+ SS+  +  SL+   SP               TY+   +    F     I     D +  T   +G+ A    SNY  L               SL K    A+++ +Y+A   ++L+  PGQ + I   +   W++ +L   G   + GW P                      + Y + L+  G+  ++         +    ++I MY Y+AQN DEL+F K  I+ +++K++P+WW+G       +GLFP NYV+      + D         +PS +              W  D  ++   +LT  E++RQ YI ELI TE+ Y  DLQ V  +F +P+ +S LLT +E+  IF+NW +LI  +     AL++RK  SG K P++ +GDIL +  P+   Y+RFCS Q    AL+++K   +  FKEF ++   + RCK MP+SS+ LKPMQR+T+Y LI++NIL+NT + HPD   ++ A+  A  LC  VNEG+REKENS+RLEWIQ HVQC+GL+E+L FNS TN LG RK ++SG LYKAKS KEL GFLFNDFLLL  +T    ++G   VF    S    +Q+KMYK PI LN VL+ +   PS                      IF I      + L+A S+N+R  WV+++ AAS  YIETE   RE +  +R  R+ G+GRL+V V+EG  LK   +   K++ YCE ++G+Q   TK +  T NPKWN + QF I+++E +VLC++ ++++ F+P+DFLGRTE+ + DIK+ +  +KGP+ + L L  V +GE++V+LDL  F
Sbjct:  915 GLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDMWWFGEVQG--QKGWFPKSYVK-LISGPIRKSTSMDSGSSE--SPASLKRVASPAAKPVVSGEEFIAMYTYESSEQGDLTFQQGDVILVTKKDGDWWT-GTVGDKAGVFPSNYVRL--KDSEGSGTAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFP----------------------ANYVKLLSP-GTSKITPTEPPKSTALAAVCQVIGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGE--VNGQVGLFPSNYVK-----LTTD--------MDPSQQ--------------WCSD--LHLLDMLTPTERKRQGYIHELIVTEENYVNDLQLVTEIFQKPLMESELLTEKEVAMIFVNWKELIMCNIKLLKALRVRKKMSGEKMPVKMIGDILSAQLPHMQPYIRFCSRQLNGAALIQQKTDEAPDFKEFVKRLAMDPRCKGMPLSSFILKPMQRVTRYPLIIKNILENTPENHPDHSHLKHALEKAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQITKPLGSSGTDKVF----SPKSNLQYKMYKTPIFLNEVLVKLPTDPSGDE------------------PIFHISHIDRVYTLRAESINERTAWVQKIKAASELYIETEKKKREKAYLVRSQRATGIGRLMVNVVEGIELKPCRS-HGKSNPYCEVTMGSQCHITKTIQDTLNPKWNSNCQFFIRDLEQEVLCITVFERDQFSPDDFLGRTEIRVADIKKDQ-GSKGPVTKCLLLHEVPTGEIVVRLDLQLF 1718          

Query:   74 GNQSQWSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPP------DSFPFSDLGANEIFSSKAAPSYNEV----MAKDKADRQSFREKPPIPQDIQSTFPPLP---------------KRTSPQT---------------------DWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSMVTISNNNKSLPNSHTEHEWTATSESRPGTLKACPASPQIIQETSMNTAQWNKPLPVTPEIEIQSQIHQ-KLEKEKQRLIDLEETRLQQAVXXXXXXXXXXXXXXDRQE 1153
            G+   W+I+ EE ++H  QF  L P+ GFI+G QA+ +  +S L   +L +IW+LAD++ DGRM   EFSIAM LIK KL+G +LP+ LP  M   P       +F    + +    ++ A      +    M+            PP+         PLP                R+ P +                     +W + Q+ R +YR  FN  D+   G L+G +A+ +L+QS L  + LA IWNLSDID DGKLT EEF +AM+L++ A +G+ LP  LP   +PPS   + + +     S T  +            +  P  P +  E      Q  K LPVT E + +    +  LE EK+R   LE+ R +Q    +    E  +K ++RQE
Sbjct:   10 GSLDIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQGYQLPSALPPVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLANGAPPVIQPLPAFAHPAATLPKSSSFSRSGPGSQLNTKLQKAQSFDVASVPPVAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGISVISSTSVD------------QRLPEEPVLEDEQQ----QLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQE 400          

Query: 1733 ESYQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNVFDQTLPDGATIKKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMS-THWWKGHIRGARENGMFPSHYVKKLTKQD 2557
            E + A+Y +   +  +LTF+ GD+ILV           W  G   +    G+FP+ YV+              DSE S          T     ++ K P    V A +          P+QL+   GQ I + ++  G WW+GE+    +  G    +GWFP  YV+ +      +  TE     +    AA   + G                     +Y Y +    +L    G II +++     WWKG + G  + G+FPS+YVK  T  D
Sbjct: 1005 EEFIAMYTYESSEQGDLTFQQGDVILV-----TKKDGDWWTG--TVGDKAGVFPSNYVR------------LKDSEGSG---------TAGKTGSLGKKPEIAQVIASY------TATGPEQLTLAPGQLILIRKKNPGGWWEGEL----QARGKKRQIGWFPANYVKLLSPGTSKITPTEPPKSTA---LAAVCQVIG---------------------MYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNG--QVGLFPSNYVKLTTDMD 1216          

Query: 2045 VEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVK--------------KLTKQDLEHAQTIDTISSDYYTALSLENSNSPTMTYDDIGRNLNDFDTDSGITDPELATPAEIGENAAY-SNYCTLAXXXXXXXXXXXXXXXLSKAKIVRA-----YSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTN 2956
             +A++PW    ++     L+FN    I V+E++   WW GE+             GWFP+ YV+ +        S +S    S  +          P+            GE  +A+Y YES+  GDLT + GD+I +      WW G +    + G+FPS+YV+               L K+  E AQ I + ++     L+L       +   + G          G  + EL    +  +   + +NY  L      + +      S + A + +      Y+A + DEL+   GQ +N+++  D DW+K +  +NG   
Sbjct:  918 AQALYPWRAKKDN----HLNFNKNDVITVLEQQDM-WWFGEVQGQK---------GWFPKSYVKLISGPIRKSTSMDSGSSESPASLKRVASPAAKPVVS----------GEEFIAMYTYESSEQGDLTFQQGDVILVTKKDGDWWTGTV--GDKAGVFPSNYVRLKDSEGSGTAGKTGSLGKKP-EIAQVIASYTATGPEQLTLAPGQLILIRKKNPG----------GWWEGELQARGKKRQIGWFPANYVKLLSPGTSKITPTEPPKSTALAAVCQVIGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGE--VNGQVG 1202          

Query: 2051 AIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGD--WWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYS-NETLLSTESTM-------------------------------KYSNLNFAASNDIFGAPIXXXXXXXXXXXXGE-------YCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQTIDTISSDYYTALSLENSNSPTMTYDDIGRNLNDFDTDSGITDPELA-TPAE---------------IGENAAY--SNYCTLAXXXXXXXXXXXXXXXLSK--AKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNE-GWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTV-VGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLL---VTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLI-MAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIR--RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFF 4957
            A++P+    E    D++SFN G  I+V E+  G+  W  G    +          GWFP  YV+ +  S NE  +S +  +                                +SNL    S     A     +  + S   G+          AL  + +     L     DII +++   +WW G + G R  G FP  YVK +   +++  +           AL    +  PT     +G         S +   +L  T  E               IG+ +    SNY    +      ++ S  ++     A++  AY A   ++LS  PGQ + I+  +   W++ +L   G   + GW P   +                          ++G  P SER+        P  ++IAMY Y+A N DELSF+K  ++ +++KD+P+WW+G      + GLFP NYV+      + D         +PS +      T+   +PI                 E++RQ YI ELI+TE+ Y  DLQ V  VF + + +S  LT  E+  IF+NW +LI  +     AL++RK   G K P+Q +GDIL +   +   Y+RFCS Q    ALL++K      FKEF ++   + RCK MP+SS+ LKPMQRIT+Y L++ +IL+NT + H D   ++ A+  A  LC  VNEG+REKENS+RLEWIQ HVQC+GL E+L FNS TN LG RKL++SG LYK KS KEL GFLFNDFLLL   V     ++G   +F    SS    QFKMYK PI LN VL+ +   PS                  S   +F I      + L+  ++N+R  WV+++ AAS QYI+TE   RE +   R  +++G+GRL+V V+E   LK+   P  K++ YCE S+G+Q   T+ +  T NPKWN + QF IK++  DVLCL+ +D++ F+P+DFLGRTE+ +  I+  +  +KGP+ RRL L  V +GE+ V+ DL  F
Sbjct:  737 ALYPF----EARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGN---------FGWFPCNYVEKMPSSENEKAVSPKKALLPPTVSLSATSTSSEPLSSNQPASVTDYQNVSFSNLTVNTSWQKKSAFTRTVSPGSVSPIHGQGQVVENLKAQALCSWTAKKDNHLNFSKHDIITVLEQQENWWFGEVHGGR--GWFPKSYVKIIPGSEVKREEP---------EALYAAVNKKPTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEEILVTQKDGEWWTGSIGDRSGIFPSNYVKPKDQESFGSASKSGASNKKPEIAQVTSAYVASGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVK-------------------------LLG--PSSERA---TPAFHPVCQVIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGE--INGVTGLFPSNYVK-----MTTDS--------DPSQQWCADLQTLDTMQPI-----------------ERKRQGYIHELIQTEERYMADLQLVVEVFQKRMAESGFLTEGEMALIFVNWKELIMSNTKLLKALRVRKKTGGEKMPVQMIGDILAAELSHMQAYIRFCSCQLNGAALLQQKTDEDTDFKEFLKKLASDPRCKGMPLSSFLLKPMQRITRYPLLIRSILENTPESHADHSSLKLALERAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLAEQLIFNSLTNCLGPRKLLHSGKLYKTKSNKELHGFLFNDFLLLTYMVKQFAVSSGSEKLF----SSKSNAQFKMYKTPIFLNEVLVKLPTDPS------------------SDEPVFHISHIDRVYTLRTDNINERTAWVQKIKAASEQYIDTEKKKREKAYQARSQKTSGIGRLMVHVIEATELKACK-PNGKSNPYCEISMGSQSYTTRTIQDTLNPKWNFNCQFFIKDLYQDVLCLTLFDRDQFSPDDFLGRTEIPVAKIRTEQ-ESKGPMTRRLLLHEVPTGEVWVRFDLQLF 1664          

Query: 1730 LESYQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPD----------SETSTDKE-------------QNV----------------FDQTLPDGATI-----KKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQT---------IDTISSDYYTALSLENSNSPTMTYDDIGRNLNDFDTDSGITDPELATPAEIGENAAY-SNYCTLAXXXXXXXXXXXXXXXLSKAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTN 2956
            L +Y+ALY F  R  DE++F +GDII V   +      GWL G  + N  FG FP  YV+K+ P   NE  ++P           S TST  E             QNV                F +T+  G+        +   N+  +A+  W    ++     L+F+    I V+E++  +WW GE+             GWFP+ YV+ +  S   +   E    Y+ +N   ++  +                GE  +ALYPY S  PGDLT   G+ I +      WW G I G R +G+FPS+YVK   ++    A           I  ++S Y  + S + S +P      + +N       SG    EL    +  +   + +++  L       +      + + +   +  Y+A++ DELS   GQ +N+++  D DW++ +  ING T 
Sbjct:  732 LVNYRALYPFEARNHDEMSFNSGDIIQVDEKTVGE--PGWLYGSFQGN--FGWFPCNYVEKM-PSSENEKAVSPKKALLPPTVSLSATSTSSEPLSSNQPASVTDYQNVSFSNLTVNTSWQKKSAFTRTVSPGSVSPIHGQGQVVENLKAQALCSWTAKKDN----HLNFSKHDIITVLEQQE-NWWFGEVHG---------GRGWFPKSYVKIIPGSE--VKREEPEALYAAVNKKPTSAAYSV--------------GEEYIALYPYSSVEPGDLTFTEGEEILVTQKDGEWWTGSI-GDR-SGIFPSNYVKPKDQESFGSASKSGASNKKPEIAQVTSAYVASGSEQLSLAPGQLILILKKN------TSGWWQGELQARGKKRQKGWFPASHVKL--LGPSSERATPAFHPVCQVIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGE--INGVTG 1147          

Query:   62 SIMLGNQSQWSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPPDSFPF 379
            + M G  + W+I++EE ++H  QF++L P  G+I+G QA+ +  +S L   +L +IW+L+D+++DG+M   EFSIAM LIK KL+G +LP VLP  M  PP   P 
Sbjct:    7 TAMNGGPNMWAITSEERTKHDRQFDNLKPSGGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVLPPIMKQPPMFSPL 112          

Query:  536 SPQT---DWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGR 787
            SP+T   +W + Q  R +YR +FN  D++  G+LSG +A+  LLQS LS + LA IW L+D+D DG+L  EEF +AM+L + A+AG+
Sbjct:  230 SPKTGTSEWAVPQPTRLKYRQKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLATIWTLADVDGDGQLKAEEFILAMHLTDMAKAGQ 316          

Query:  551 WVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSMVT 838
            W I    R ++  QF+   +   G+++GD+A+   LQSGL   +LA+IW LSD++ DGK+  +EF +AM L++    G+ LP  LP  +  P M +
Sbjct:   16 WAITSEERTKHDRQFDNL-KPSGGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVLPPIMKQPPMFS 110          

Query:   83 SQWSISTEEFSQHRIQFEHLN-PVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHL 298
            S+W++      ++R +F  L+  + G++SG QA+  L +S LS   L  IW+LADVD DG++   EF +AMHL
Sbjct:  236 SEWAVPQPTRLKYRQKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLATIWTLADVDGDGQLKAEEFILAMHL 308          

Query: 2051 AIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGD--WWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYS-NETLLSTESTM-------------------------------KYSNLNFAASNDIFGAPIXXXXXXXXXXXXGE-------YCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQTIDTISSDYYTALSLENSNSPTMTYDDIGRNLNDFDTDSGITDPELA-TPAE---------------IGENAAY--SNYCTLAXXXXXXXXXXXXXXXLSK--AKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNE-GWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTV-VGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLL---VTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLI-MAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIR--RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFF 4957
            A++P+    E    D++SFN G  I+V E+  G+  W  G    +          GWFP  YV+ +  S NE  +S +  +                                +SNL    S     A     +  + S   G+          AL  + +     L     DII +++   +WW G + G R  G FP  YVK +   +++  +           AL    +  PT     +G         S +   +L  T  E               IG+ +    SNY    +      ++ S  ++     A++  AY A   ++LS  PGQ + I+  +   W++ +L   G   + GW P   +                          ++G  P SER+        P  ++IAMY Y+A N DELSF+K  ++ +++KD+P+WW+G      + GLFP NYV+      + D         +PS +      T+   +PI                 E++RQ YI ELI+TE+ Y  DLQ V  VF + + +S  LT  E+  IF+NW +LI  +     AL++RK   G K P+Q +GDIL +   +   Y+RFCS Q    ALL++K      FKEF ++   + RCK MP+SS+ LKPMQRIT+Y L++ +IL+NT + H D   ++ A+  A  LC  VNEG+REKENS+RLEWIQ HVQC+GL E+L FNS TN LG RKL++SG LYK KS KEL GFLFNDFLLL   V     ++G   +F    SS    QFKMYK PI LN VL+ +   PS                  S   +F I      + L+  ++N+R  WV+++ AAS QYI+TE   RE +   R  +++G+GRL+V V+E   LK+   P  K++ YCE S+G+Q   T+ +  T NPKWN + QF IK++  DVLCL+ +D++ F+P+DFLGRTE+ +  I+  +  +KGP+ RRL L  V +GE+ V+ DL  F
Sbjct:  747 ALYPF----EARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGN---------FGWFPCNYVEKMPSSENEKAVSPKKALLPPTVSLSATSTSSEPLSSNQPASVTDYQNVSFSNLTVNTSWQKKSAFTRTVSPGSVSPIHGQGQVVENLKAQALCSWTAKKDNHLNFSKHDIITVLEQQENWWFGEVHGGR--GWFPKSYVKIIPGSEVKREEP---------EALYAAVNKKPTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEEILVTQKDGEWWTGSIGDRSGIFPSNYVKPKDQESFGSASKSGASNKKPEIAQVTSAYVASGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVK-------------------------LLG--PSSERA---TPAFHPVCQVIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGE--INGVTGLFPSNYVK-----MTTDS--------DPSQQWCADLQTLDTMQPI-----------------ERKRQGYIHELIQTEERYMADLQLVVEVFQKRMAESGFLTEGEMALIFVNWKELIMSNTKLLKALRVRKKTGGEKMPVQMIGDILAAELSHMQAYIRFCSCQLNGAALLQQKTDEDTDFKEFLKKLASDPRCKGMPLSSFLLKPMQRITRYPLLIRSILENTPESHADHSSLKLALERAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLAEQLIFNSLTNCLGPRKLLHSGKLYKTKSNKELHGFLFNDFLLLTYMVKQFAVSSGSEKLF----SSKSNAQFKMYKTPIFLNEVLVKLPTDPS------------------SDEPVFHISHIDRVYTLRTDNINERTAWVQKIKAASEQYIDTEKKKREKAYQARSQKTSGIGRLMVHVIEATELKACK-PNGKSNPYCEISMGSQSYTTRTIQDTLNPKWNFNCQFFIKDLYQDVLCLTLFDRDQFSPDDFLGRTEIPVAKIRTEQ-ESKGPMTRRLLLHEVPTGEVWVRFDLQLF 1674          

Query: 1730 LESYQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPD----------SETSTDKE-------------QNV----------------FDQTLPDGATI-----KKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQT---------IDTISSDYYTALSLENSNSPTMTYDDIGRNLNDFDTDSGITDPELATPAEIGENAAY-SNYCTLAXXXXXXXXXXXXXXXLSKAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTN 2956
            L +Y+ALY F  R  DE++F +GDII V   +      GWL G  + N  FG FP  YV+K+ P   NE  ++P           S TST  E             QNV                F +T+  G+        +   N+  +A+  W    ++     L+F+    I V+E++  +WW GE+             GWFP+ YV+ +  S   +   E    Y+ +N   ++  +                GE  +ALYPY S  PGDLT   G+ I +      WW G I G R +G+FPS+YVK   ++    A           I  ++S Y  + S + S +P      + +N       SG    EL    +  +   + +++  L       +      + + +   +  Y+A++ DELS   GQ +N+++  D DW++ +  ING T 
Sbjct:  742 LVNYRALYPFEARNHDEMSFNSGDIIQVDEKTVGE--PGWLYGSFQGN--FGWFPCNYVEKM-PSSENEKAVSPKKALLPPTVSLSATSTSSEPLSSNQPASVTDYQNVSFSNLTVNTSWQKKSAFTRTVSPGSVSPIHGQGQVVENLKAQALCSWTAKKDN----HLNFSKHDIITVLEQQE-NWWFGEVHG---------GRGWFPKSYVKIIPGSE--VKREEPEALYAAVNKKPTSAAYSV--------------GEEYIALYPYSSVEPGDLTFTEGEEILVTQKDGEWWTGSI-GDR-SGIFPSNYVKPKDQESFGSASKSGASNKKPEIAQVTSAYVASGSEQLSLAPGQLILILKKN------TSGWWQGELQARGKKRQKGWFPASHVKL--LGPSSERATPAFHPVCQVIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGE--INGVTG 1157          

Query:   62 SIMLGNQSQWSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPPDSFPF 379
            + M G  + W+I++EE ++H  QF++L P  G+I+G QA+ +  +S L   +L +IW+L+D+++DG+M   EFSIAM LIK KL+G +LP VLP  M  PP   P 
Sbjct:   17 TAMNGGPNMWAITSEERTKHDRQFDNLKPSGGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVLPPIMKQPPMFSPL 122          

Query:  536 SPQT---DWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGR 787
            SP+T   +W + Q  R +YR +FN  D++  G+LSG +A+  LLQS LS + LA IW L+D+D DG+L  EEF +AM+L + A+AG+
Sbjct:  240 SPKTGTSEWAVPQPTRLKYRQKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLATIWTLADVDGDGQLKAEEFILAMHLTDMAKAGQ 326          

Query:  551 WVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSMVT 838
            W I    R ++  QF+   +   G+++GD+A+   LQSGL   +LA+IW LSD++ DGK+  +EF +AM L++    G+ LP  LP  +  P M +
Sbjct:   26 WAITSEERTKHDRQFDNL-KPSGGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVLPPIMKQPPMFS 120          

Query:   83 SQWSISTEEFSQHRIQFEHLN-PVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHL 298
            S+W++      ++R +F  L+  + G++SG QA+  L +S LS   L  IW+LADVD DG++   EF +AMHL
Sbjct:  246 SEWAVPQPTRLKYRQKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLATIWTLADVDGDGQLKAEEFILAMHL 318          

Query: 2051 AIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGD--WWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYS-NETLLSTESTM-------------------------------KYSNLNFAASNDIFGAPIXXXXXXXXXXXXGE-------YCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQTIDTISSDYYTALSLENSNSPTMTYDDIGRNLNDFDTDSGITDPELA-TPAE---------------IGENAAY--SNYCTLAXXXXXXXXXXXXXXXLSK--AKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNE-GWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTV-VGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLL---VTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLI-MAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIR--RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFF 4957
            A++P+    E    D++SFN G  I+V E+  G+  W  G    +          GWFP  YV+ +  S NE  +S +  +                                +SNL    S     A     +  + S   G+          AL  + +     L     DII +++   +WW G + G R  G FP  YVK +   +++  +           AL    +  PT     +G         S +   +L  T  E               IG+ +    SNY    +      ++ S  ++     A++  AY A   ++LS  PGQ + I+  +   W++ +L   G   + GW P   +                          ++G  P SER+        P  ++IAMY Y+A N DELSF+K  ++ +++KD+P+WW+G      + GLFP NYV+      + D         +PS +      T+   +PI                 E++RQ YI ELI+TE+ Y  DLQ V  VF + + +S  LT  E+  IF+NW +LI  +     AL++RK   G K P+Q +GDIL +   +   Y+RFCS Q    ALL++K      FKEF ++   + RCK MP+SS+ LKPMQRIT+Y L++ +IL+NT + H D   ++ A+  A  LC  VNEG+REKENS+RLEWIQ HVQC+GL E+L FNS TN LG RKL++SG LYK KS KEL GFLFNDFLLL   V     ++G   +F    SS    QFKMYK PI LN VL+ +   PS                  S   +F I      + L+  ++N+R  WV+++ AAS QYI+TE   RE +   R  +++G+GRL+V V+E   LK+   P  K++ YCE S+G+Q   T+ +  T NPKWN + QF IK++  DVLCL+ +D++ F+P+DFLGRTE+ +  I+  +  +KGP+ RRL L  V +GE+ V+ DL  F
Sbjct:  764 ALYPF----EARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGN---------FGWFPCNYVEKMPSSENEKAVSPKKALLPPTVSLSATSTSSEPLSSNQPASVTDYQNVSFSNLTVNTSWQKKSAFTRTVSPGSVSPIHGQGQVVENLKAQALCSWTAKKDNHLNFSKHDIITVLEQQENWWFGEVHGGR--GWFPKSYVKIIPGSEVKREEP---------EALYAAVNKKPTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEEILVTQKDGEWWTGSIGDRSGIFPSNYVKPKDQESFGSASKSGASNKKPEIAQVTSAYVASGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVK-------------------------LLG--PSSERA---TPAFHPVCQVIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGE--INGVTGLFPSNYVK-----MTTDS--------DPSQQWCADLQTLDTMQPI-----------------ERKRQGYIHELIQTEERYMADLQLVVEVFQKRMAESGFLTEGEMALIFVNWKELIMSNTKLLKALRVRKKTGGEKMPVQMIGDILAAELSHMQAYIRFCSCQLNGAALLQQKTDEDTDFKEFLKKLASDPRCKGMPLSSFLLKPMQRITRYPLLIRSILENTPESHADHSSLKLALERAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLAEQLIFNSLTNCLGPRKLLHSGKLYKTKSNKELHGFLFNDFLLLTYMVKQFAVSSGSEKLF----SSKSNAQFKMYKTPIFLNEVLVKLPTDPS------------------SDEPVFHISHIDRVYTLRTDNINERTAWVQKIKAASEQYIDTEKKKREKAYQARSQKTSGIGRLMVHVIEATELKACK-PNGKSNPYCEISMGSQSYTTRTIQDTLNPKWNFNCQFFIKDLYQDVLCLTLFDRDQFSPDDFLGRTEIPVAKIRTEQ-ESKGPMTRRLLLHEVPTGEVWVRFDLQLF 1691          

Query: 1730 LESYQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPD----------SETSTDKE-------------QNV----------------FDQTLPDGATI-----KKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQT---------IDTISSDYYTALSLENSNSPTMTYDDIGRNLNDFDTDSGITDPELATPAEIGENAAY-SNYCTLAXXXXXXXXXXXXXXXLSKAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTN 2956
            L +Y+ALY F  R  DE++F +GDII V   +      GWL G  + N  FG FP  YV+K+ P   NE  ++P           S TST  E             QNV                F +T+  G+        +   N+  +A+  W    ++     L+F+    I V+E++  +WW GE+             GWFP+ YV+ +  S   +   E    Y+ +N   ++  +                GE  +ALYPY S  PGDLT   G+ I +      WW G I G R +G+FPS+YVK   ++    A           I  ++S Y  + S + S +P      + +N       SG    EL    +  +   + +++  L       +      + + +   +  Y+A++ DELS   GQ +N+++  D DW++ +  ING T 
Sbjct:  759 LVNYRALYPFEARNHDEMSFNSGDIIQVDEKTVGE--PGWLYGSFQGN--FGWFPCNYVEKM-PSSENEKAVSPKKALLPPTVSLSATSTSSEPLSSNQPASVTDYQNVSFSNLTVNTSWQKKSAFTRTVSPGSVSPIHGQGQVVENLKAQALCSWTAKKDN----HLNFSKHDIITVLEQQE-NWWFGEVHG---------GRGWFPKSYVKIIPGSE--VKREEPEALYAAVNKKPTSAAYSV--------------GEEYIALYPYSSVEPGDLTFTEGEEILVTQKDGEWWTGSI-GDR-SGIFPSNYVKPKDQESFGSASKSGASNKKPEIAQVTSAYVASGSEQLSLAPGQLILILKKN------TSGWWQGELQARGKKRQKGWFPASHVKL--LGPSSERATPAFHPVCQVIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGE--INGVTG 1174          

Query:   62 SIMLGNQSQWSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPPDSFPF 379
            + M G  + W+I++EE ++H  QF++L P  G+I+G QA+ +  +S L   +L +IW+L+D+++DG+M   EFSIAM LIK KL+G +LP VLP  M  PP   P 
Sbjct:    7 TAMNGGPNMWAITSEERTKHDRQFDNLKPSGGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVLPPIMKQPPMFSPL 112          

Query:  536 SPQT---DWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGR 787
            SP+T   +W + Q  R +YR +FN  D++  G+LSG +A+  LLQS LS + LA IW L+D+D DG+L  EEF +AM+L + A+AG+
Sbjct:  230 SPKTGTSEWAVPQPTRLKYRQKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLATIWTLADVDGDGQLKAEEFILAMHLTDMAKAGQ 316          

Query:  551 WVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSMVT 838
            W I    R ++  QF+   +   G+++GD+A+   LQSGL   +LA+IW LSD++ DGK+  +EF +AM L++    G+ LP  LP  +  P M +
Sbjct:   16 WAITSEERTKHDRQFDNL-KPSGGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVLPPIMKQPPMFS 110          

Query:   83 SQWSISTEEFSQHRIQFEHLN-PVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHL 298
            S+W++      ++R +F  L+  + G++SG QA+  L +S LS   L  IW+LADVD DG++   EF +AMHL
Sbjct:  236 SEWAVPQPTRLKYRQKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLATIWTLADVDGDGQLKAEEFILAMHL 308          

Query:   86 QWSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPPDSFPFSDLGANEIFSSKAAPSYNEVMAKDKADRQSFREKPPIPQDIQST----FPPLPKR---------------------------TSPQTDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSM 832
            QW I+  + +++   F+ LNPV G +SG   +  L  S L    L +IW L+D D+DG +   E S+A+HL+ + L+   +P  LP  ++ P  +     + A+   +  A P     M   +A   +  +   + Q   +T    +PP P R                           + P  +W I       Y  QF Q D NK G + G + +A ++ +GLS  ILA +W L+DI   G+L  E+F + M+L++ A+ G ++PS+LP  L+PPS 
Sbjct:  155 QWPITPTDQAKYDSIFQSLNPVNGKLSGAHVRPVLMNSGLDAHALARIWELSDQDKDGNLDRIEMSVALHLVYRSLQSDPVPAQLPPNLIHPSKA-----MYAHSSPNFAAPPHPPRPMMGSRAGSVTSLDDVNMSQSYSATMPRAYPPQPGRAYSAQAHVNGSRTSGASTPISASHSIHSFPAGEWPINTG---DYADQFAQTDTNKDGLVDGMDMRAPMMTTGLSAQILAHVWALADIKKCGQLNLEQFALTMHLLDMAKRGESIPSELPLHLIPPSF 426          

Query:   89 WSISTEEFSQHRIQFEHLNPVKG-FISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPPDSFPFSDLGANEIFSSKAAPSYNEV-------MAKDKADRQSFREKPPIPQDIQSTFPPLPKRTSPQTDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPS--MVTISNNNKSLP 865
            ++I+T         F  +NP     I   +A  +L KS L+  +LG+IW L+D  + G +      +A  L+    +G  + N    +  + P  F      AN        PS+  V            +   S   +   P    S FPP          W I    + +Y   F Q      G LSG   + VL+ SGL    LA+IW LSD D DG L   E  VA++LV ++     +P++LP  L+ PS  M   S+ N + P
Sbjct:    5 YAIATPHNDVFNHAFAEMNPHGAPRIGAAEAATFLKKSNLAMPVLGQIWELSDSQKVGSLDKRGAFVAFKLVAAAQQGKPVANSSLYDSSLQPPRFAPPVPPAN--MQHHFQPSFPSVGRAPPVPPPPHPSHPYSISSQQSSPAHPSSAFPP---------QWPITPTDQAKYDSIF-QSLNPVNGKLSGAHVRPVLMNSGLDAHALARIWELSDQDKDGNLDRIEMSVALHLVYRSLQSDPVPAQLPPNLIHPSKAMYAHSSPNFAAP 261          

Query:   83 SQWSISTEEFSQHRIQFEHLNPVK-GFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPPDSFP 376
             +W I+T +++    QF   +  K G + G+  +  +  + LS QIL  +W+LAD+ + G+++L +F++ MHL+     G  +P+ LP   L+PP   P
Sbjct:  334 GEWPINTGDYAD---QFAQTDTNKDGLVDGMDMRAPMMTTGLSAQILAHVWALADIKKCGQLNLEQFALTMHLLDMAKRGESIPSELPLH-LIPPSFRP 428          

Query:   89 WSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLV-----PPDSFPFSDLGANEIFSSKAAPSYNEVMAKDKADRQSFREKPPIPQDIQSTFPPLPKRTSPQT-----------------DWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSMVTISNNN 853
            W +S  E+ ++   F  L   + F+  + A+  L +S L  Q+L +IW+L+D+D+DGR+ + E+SIAM L    L GI +P  LP  +LV      P ++P S  G+ + +S    P+ +  M+      QS+   P  P  I  T  P  +  S                    +W I    + +Y   FN  D+ + G LS    ++ L  SGL  ++LA IW LSD++ DGKL+ +E+ ++ Y++E  ++G ALP   P  LV   M  IS+ +
Sbjct:    5 WEVSDAEYQKNFAMFGQLTGGQPFMDAVTARNALMRSNLPTQVLSQIWALSDLDKDGRLDIREYSIAMRLALNCLAGIPIPPQLPPSLLVVPARNAPPTWPGSRHGSVD-YSQTLPPAIDRRMS------QSY--IPSAPVSIAGT--PSSRHNSISAGSPLNNDRNVFEGRQLENWAIPHHNKLKYSQLFNALDKERLGSLSSQVGRSALGLSGLPTNVLAHIWFLSDVNKDGKLSVDEYAISQYMIEMFKSGFALPKITPLELV--RMCGISSRS 268          

Query: 1742 QALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLD---------PVQSNELVLTPDSET------STDKEQNVFDQTLPDGATIKKAPNNVWVEAI------FPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASN----DIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQ 2554
            +AL+ F  R  DEL+FE GD+I+V   S A  P GW  G+L+  +  G FP  +V+ +          P+Q+    +TP S        +  K +      L +G     +        I      F W    E++    LSF  G  I V+E++    WKG         G+I   GWFP+ YV+ V  +  T     S  K S     A+     D+   P       + +    +    +Y +E+    DL +  GD I +++ +  WWKG   G RE G+FP++YV+   +Q
Sbjct:  669 RALFAFEARSEDELSFEPGDVIIVFQ-SHAAEP-GWRAGQLR--EKVGWFPEAFVEAIAAVPTPGGDPPIQNMPPNMTPSSSVDQIGVKAARKAEIAAAMGLTEGGAPPASSAPAAAAVISQCIAQFQWRARNEED----LSFAKGDTIEVLEKQEMK-WKGRNPA-----GEI---GWFPKSYVKEVGATTSTTTPIVSPSKASAGAPGAAAGAQYDVV--PSDVTLQASETAPQQQLYTVIYDFEAVETTDLALHVGDTILVLEKNDEWWKGRCNG-RE-GIFPANYVEISVQQ 943          

Query: 1739 YQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNVFDQTLPDGATIKKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMS-THWWKGHI-RGARENGMFPSHYVKK 2542
            Y  +Y F   +T +L    GD ILV   +       W  GR   N   G+FP  YV                 E S    Q   D T P  A    AP  V  EA    ++D     P+QL   VG+ +++ E+ +  WW+GE+  + +        GWFP  YV+ ++ +     +T +T                                    A+Y YE++ P +L  + GD+I + D S   WW GH  +   ++G+FPS+YV++
Sbjct:  889 YTVIYDFEAVETTDLALHVGDTILVLEKNDE-----WWKGRC--NGREGIFPANYV-----------------EISV---QQAGDPTPPTQAPTPAAPPTVLCEAKV--VVDFVASAPNQLGIKVGEIVKIREKSAAGWWEGELIRNGKP-----IAGWFPGEYVKVLEEAASP--ATRAT------------------------------------AVYDYEASQPDELGFKTGDVIIVTDKSEAEWWSGHREQDPSKSGLFPSNYVQQ 1086          

Query: 2813 LSKAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNEGWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRG-RNIATSMIGLFPVNYVRR 3292
            L +AK+V  + A + ++L    G+ V I + S   W++ +L  NG    GW P                                      E  + +++   P  +  A+Y Y A  PDEL F    ++ +  K E EWW G R    S  GLFP NYV++
Sbjct:  963 LCEAKVVVDFVASAPNQLGIKVGEIVKIREKSAAGWWEGELIRNGKPIAGWFP-------------------------------------GEYVKVLEEAASPATRATAVYDYEASQPDELGFKTGDVIIVTDKSEAEWWSGHREQDPSKSGLFPSNYVQQ 1086          

Query:   89 WSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLV-----PPDSFPFSDLGANEIFSSKAAPSYNEVMAKDKADRQSFREKPPIPQDIQSTFPPLPKRTSPQT-----------------DWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSMVTISNNN 853
            W +S  E+ ++   F  L   + F+  + A+  L +S L  Q+L +IW+L+D+D+DGR+ + E+SIAM L    L GI +P  LP  +LV      P ++P S  G+ + +S    P+ +  M+      QS+   P  P  I  T  P  +  S                    +W I    + +Y   FN  D+ + G LS    ++ L  SGL  ++LA IW LSD++ DGKL+ +E+ ++ Y++E  ++G ALP   P  LV   M  IS+ +
Sbjct:    5 WEVSDAEYQKNFAMFGQLTGGQPFMDAVTARNALMRSNLPTQVLSQIWALSDLDKDGRLDIREYSIAMRLALNCLAGIPIPPQLPPSLLVVPARNAPPTWPGSRHGSVD-YSQTLPPAIDRRMS------QSY--IPSAPVSIAGT--PSSRHNSISAGSPLNNDRNVFEGRQLENWAIPHHNKLKYSQLFNALDKERLGSLSSQVGRSALGLSGLPTNVLAHIWFLSDVNKDGKLSVDEYAISQYMIEMFKSGFALPKITPLELV--RMCGISSRS 268          

Query: 1742 QALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLD---------PVQSNELVLTPDSET------STDKEQNVFDQTLPDGATIKKAPNNVWVEAI------FPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASN----DIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQ 2554
            +AL+ F  R  DEL+FE GD+I+V   S A  P GW  G+L+  +  G FP  +V+ +          P+Q+    +TP S        +  K +      L +G     +        I      F W    E++    LSF  G  I V+E++    WKG         G+I   GWFP+ YV+ V  +  T     S  K S     A+     D+   P       + +    +    +Y +E+    DL +  GD I +++ +  WWKG   G RE G+FP++YV+   +Q
Sbjct:  667 RALFAFEARSEDELSFEPGDVIIVFQ-SHAAEP-GWRAGQLR--EKVGWFPEAFVEAIAAVPTPGGDPPIQNMPPNMTPSSSVDQIGVKAARKAEIAAAMGLTEGGAPPASSAPAAAAVISQCIAQFQWRARNEED----LSFAKGDTIEVLEKQEMK-WKGRNPA-----GEI---GWFPKSYVKEVGATTSTTTPIVSPSKASAGAPGAAAGAQYDVV--PSDVTLQASETAPQQQLYTVIYDFEAVETTDLALHVGDTILVLEKNDEWWKGRCNG-RE-GIFPANYVEISVQQ 941          

Query: 1739 YQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNVFDQTLPDGATIKKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMS-THWWKGHI-RGARENGMFPSHYVKK 2542
            Y  +Y F   +T +L    GD ILV   +       W  GR   N   G+FP  YV                 E S    Q   D T P  A    AP  V  EA    ++D     P+QL   VG+ +++ E+ +  WW+GE+  + +        GWFP  YV+ ++ +     +T +T                                    A+Y YE++ P +L  + GD+I + D S   WW GH  +   ++G+FPS+YV++
Sbjct:  887 YTVIYDFEAVETTDLALHVGDTILVLEKNDE-----WWKGRC--NGREGIFPANYV-----------------EISV---QQAGDPTPPTQAPTPAAPPTVLCEAKV--VVDFVASAPNQLGIKVGEIVKIREKSAAGWWEGELIRNGKP-----IAGWFPGEYVKVLEEAASP--ATRAT------------------------------------AVYDYEASQPDELGFKTGDVIIVTDKSEAEWWSGHREQDPSKSGLFPSNYVQQ 1084          

Query: 2813 LSKAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNEGWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRG-RNIATSMIGLFPVNYVRR 3292
            L +AK+V  + A + ++L    G+ V I + S   W++ +L  NG    GW P                                      E  + +++   P  +  A+Y Y A  PDEL F    ++ +  K E EWW G R    S  GLFP NYV++
Sbjct:  961 LCEAKVVVDFVASAPNQLGIKVGEIVKIREKSAAGWWEGELIRNGKPIAGWFP-------------------------------------GEYVKVLEEAASPATRATAVYDYEASQPDELGFKTGDVIIVTDKSEAEWWSGHREQDPSKSGLFPSNYVQQ 1084          

Query:   74 GNQSQWSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPP 364
             ++++W +S E  +     FE L PV G++SG  AKE++ KSKL N +LGK+W LAD+D+DG++   EF++A +LI  KLEG E+P+ LPK  L+PP
Sbjct:  679 ADEAEWVVSRERTTADST-FESLGPVNGYLSGRAAKEHMVKSKLPNSVLGKVWKLADIDKDGQLDADEFALANYLINLKLEGHEIPSELPKH-LIPP 773          

Query:  620 GFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPS 829
            G+LSG  AK  +++S L NS+L ++W L+DID DG+L  +EF +A YL+     G  +PS+LP+ L+PPS
Sbjct:  705 GYLSGRAAKEHMVKSKLPNSVLGKVWKLADIDKDGQLDADEFALANYLINLKLEGHEIPSELPKHLIPPS 774          

Query:   74 GNQSQWSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPP 364
             ++++W +S E  +     FE L PV G++SG  AKE++ KSKL N +LGK+W LAD+D+DG++   EF++A +LI  KLEG E+P+ LPK  L+PP
Sbjct:  679 ADEAEWVVSRERTTADST-FESLGPVNGYLSGRAAKEHMVKSKLPNSVLGKVWKLADIDKDGQLDADEFALANYLINLKLEGHEIPSELPKH-LIPP 773          

Query:  620 GFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPS 829
            G+LSG  AK  +++S L NS+L ++W L+DID DG+L  +EF +A YL+     G  +PS+LP+ L+PPS
Sbjct:  705 GYLSGRAAKEHMVKSKLPNSVLGKVWKLADIDKDGQLDADEFALANYLINLKLEGHEIPSELPKHLIPPS 774          

Query: 2093 DQLSFNVGQRIRVIEEKSGD--WWKGEMCTHTEDDGDIYSVGWFPRIYVQ---------------PVDYSNETLLST------ESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKL-----TKQDLEHAQTIDTIS---SDYYTALSLENS-----------------NSPTM----TYDDIGRNLNDFDTDSGITDPELATPAEIGENAAYSNYCTLAXXXXXXXXXXXXXXXLSKAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNE-GWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYV 3286
            ++++F  G  I V  E++ +  W  GE+  HT         GWFP  YV+               PVD    T+  T       S++  ++ +  A+ D+                  EY +A YPYES   GDL+   G+++ ++     WW G I G+R  GMFPS+YV+K      +    E  +++D  +   +  YTA  +E                   +SP +     ++D+   ++  +T S     E   PAE     +YS   +   S         ++     A+++  Y A S ++LS   GQ + I   +D  W++ +L   G   + GW P   +     + ++   N     SG +         PVS    RI+   Q  DK+IA+YPY AQN DELSF K+ I+ ++ +DEPEWWRG      + GLFP NYV
Sbjct:  691 EEITFVPGDIILVPLEQNAEPGWLAGEINGHT---------GWFPESYVEKLEVGEVAPVAAVEAPVDAQVATVADTYNDNINTSSIPAASADLTAAGDV------------------EYYIAAYPYESAEEGDLSFSAGEMVMVIKKEGEWWTGTI-GSR-TGMFPSNYVQKADVGTASTAAAEPVESLDQTTLNGNAAYTAAPVEAQEQVYQPLPVQEPSEQPISSPGVGAEEAHEDLDTEVSQINTQSKTQSSE---PAE-----SYSRPMSRTSSMTPGMRAKRSEI----AQVIAPYEATSTEQLSLTRGQLIMIRKKTDSGWWEGELQAKGRRRQIGWFPATYV-----KVLQGGRN-----SGRN--------TPVS--GSRIEMTEQILDKVIALYPYKAQNDDELSFDKDDIISVLGRDEPEWWRGE--LNGLSGLFPSNYV 1078          

Query:  542 QTDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSMVTISNNNKSLPNSHTEHEWTATSESRPGTLKAC 931
            Q +W +  A + +Y   FN  DR + G+L+G +A+ VL+QS L    LAQIW LSDID DG+L C+EF +AM+L E+A AG  +P  LP+  VPP++  I    KS P S       +   SRPG+  A 
Sbjct:  182 QGEWAVQAAQKRKYTQVFNANDRTRSGYLTGSQARGVLVQSKLPQVTLAQIWTLSDIDGDGRLNCDEFILAMFLCEKAMAGEKIPVTLPQEWVPPNLRKI----KSRPGS------VSGVVSRPGSQPAS 301          

Query:   89 WSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEML 355
            W+++  E  +++ QF  L P  GF++G QAK +  +S+L   ILG+IW+LAD D DG+M+++EFSIA  LI  KL G+++P VLP  +L
Sbjct:    8 WAVTPRERLKYQEQFRALQPQAGFVTGAQAKGFFLQSQLPPLILGQIWALADTDSDGKMNINEFSIACKLINLKLRGMDVPKVLPPSLL 96          

Query: 1013 EIQSQIHQKLEKEKQRLIDLEETRLQQAVXXXXXXXXXXXXXXDRQEFLIDALAMEEEKCQMYQAKLKESLQSVESHKAHIELMRNERDELVDSTSCLFEELEAAKAEHSRCQRDRXXXXXXXXXXXXXXPFQNDLLQLENLKQLHKQSISN-LHQEIIDLQASIDLKSQNVVRNSNKLHNLENAVNCHQLAEIRRLRSNIQSKRNEVMEILEKQTQNNDVKPIFDFHQTN-----GHKLPDEFDLES-----------------------YQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLD-----PVQSNELVLTPDSETSTDK-EQNVFDQTLPDGATIKKAPNNV-WVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPI 2338
            E++++   + E EKQR  + E+ R+ +   ++ RE+E + K K     L   L+   EK +    ++ ++   V + K  I+ MR +RD  +   S L   ++   A+  +  ++R   E K      +   +N   +  N    HKQ I N +  ++ ++   I+ K +++  N  ++  L+  ++   + +   L      +R  V+E+   +     V   +D   ++     G  + D + + S                       YQA+Y+F  R  +E+TF  GDIILV  P   N   GWL G  +IN   G FP  YV+KL+     PV + E  +     T  D    N+   ++P  +    A  +V +  A +P+    E      LSF+ G+ + VI +K G+WW G + + T         G FP  YVQ  D    +  + E            +     AP+
Sbjct:  409 ELEAKEAARKELEKQRQQEWEQARIAEMNAQKEREQERVLKQKAHNTQLNVELSTLNEKIKELSQRICDTRAGVTNVKTVIDGMRTQRDTSMSEMSQLKARIKEQNAKLLQLTQERAKWEAKSKASGAALGGENAQQEQLNAAFAHKQLIINQIKDKVENISKEIESKKEDINTNDVQMSELKAELSAL-ITKCEDLYKEYDVQRTSVLELKYNRKNETSVSSAWDTGSSSAWEETGTTVTDPYAVASNDISALAAPAVDLGGPAPEGFVKYQAVYEFNARNAEEITFVPGDIILV--PLEQNAEPGWLAG--EINGHTGWFPESYVEKLEVGEVAPVAAVEAPVDAQVATVADTYNDNINTSSIPAASADLTAAGDVEYYIAAYPY----ESAEEGDLSFSAGEMVMVI-KKEGEWWTGTIGSRT---------GMFPSNYVQKADVGTASTAAAEPVESLDQTTLNGNAAYTAAPV 867          

Query:   62 SIMLGNQSQWSISTEEFSQHRIQFEHLNPVK-GFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPPD 367
            SI   NQ +W++   +  ++   F   +  + G+++G QA+  L +SKL    L +IW+L+D+D DGR++  EF +AM L +K + G ++P  LP+E  VPP+
Sbjct:  176 SIESVNQGEWAVQAAQKRKYTQVFNANDRTRSGYLTGSQARGVLVQSKLPQVTLAQIWTLSDIDGDGRLNCDEFILAMFLCEKAMAGEKIPVTLPQEW-VPPN 277          

Query:  566 AVRPRYRLQFNQQDRN---KKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLV 820
            AV PR RL++ +Q R    + GF++G +AK   LQS L   IL QIW L+D DSDGK+   EF +A  L+     G  +P  LP +L+
Sbjct:    9 AVTPRERLKYQEQFRALQPQAGFVTGAQAKGFFLQSQLPPLILGQIWALADTDSDGKMNINEFSIACKLINLKLRGMDVPKVLPPSLL 96          

Query: 2819 KAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNEGWVPRYCIDKEETQFIR-----DHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGD--KLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSA 3313
            K + V  ++A + +E++ +PG  + +    + +   +   ING T  GW P   ++K E   +      +   D   A+  D     I +  +   S    D    GD    IA YPY +    +LSF+   +V +I K E EWW G     S  G+FP NYV++     ++
Sbjct:  678 KYQAVYEFNARNAEEITFVPGDIILVPLEQNAEPGWLAGEINGHT--GWFPESYVEKLEVGEVAPVAAVEAPVDAQVATVADTYNDNINTSSIPAASA---DLTAAGDVEYYIAAYPYESAEEGDLSFSAGEMVMVIKK-EGEWWTG--TIGSRTGMFPSNYVQKADVGTAS 841          

Query: 2093 DQLSFNVGQRIRVIEEKSGD--WWKGEMCTHTEDDGDIYSVGWFPRIYVQ---------------PVDYSNETLLST------ESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKK--LTKQDLEHAQTIDTISSD-------YYTALSLENS-----------------NSPTM----TYDDIGRNLNDFDTDSGITDPELATPAEIGENAAYSNYCTLAXXXXXXXXXXXXXXXLSKAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNE-GWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYV 3286
            ++++F  G  I V  E++ +  W  GE+  HT         GWFP  YV+               PVD    T+  T       S++  ++ +  A+ D+                  EY +A YPYES   GDL+   G+++ ++     WW G I G+R  GMFPS+YV+K  +       A+ ++++  +        YTA  +E                   +SP +     ++D+   ++  +T S     E   PAE     +YS   +   S         ++     A+++  Y A S ++LS   GQ + I   +D  W++ +L   G   + GW P   +     + ++   N     SG +         PVS    RI+   Q  DK+IA+YPY AQN DELSF K+ I+ ++ +DEPEWWRG      + GLFP NYV
Sbjct:  691 EEITFVPGDIILVPLEQNAEPGWLAGEINGHT---------GWFPESYVEKLEVGEVAPVAAVEAPVDAQVATVADTYNDNINTSSIPAASADLTAAGDV------------------EYYIAAYPYESAEEGDLSFSAGEMVMVIKKEGEWWTGTI-GSR-TGMFPSNYVQKADVGTASTAAAEPVESLDQETTLNGNAAYTAAPVEAQEQVYQPLPVQEPSEQPISSPGVGAEEAHEDLDTEVSQINTQSKTQSSE---PAE-----SYSRPMSRTSSMTPGMRAKRSEI----AQVIAPYEATSTEQLSLTRGQLIMIRKKTDSGWWEGELQAKGRRRQIGWFPATYV-----KVLQGGRN-----SGRN--------TPVS--GSRIEMTEQILDKVIALYPYKAQNDDELSFDKDDIISVLGRDEPEWWRGE--LNGLSGLFPSNYV 1079          

Query:  542 QTDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSMVTISNNNKSLPNSHTEHEWTATSESRPGTLKAC 931
            Q +W +  A + +Y   FN  DR + G+L+G +A+ VL+QS L    LAQIW LSDID DG+L C+EF +AM+L E+A AG  +P  LP+  VPP++  I    KS P S       +   SRPG+  A 
Sbjct:  182 QGEWAVQAAQKRKYTQVFNANDRTRSGYLTGSQARGVLVQSKLPQVTLAQIWTLSDIDGDGRLNCDEFILAMFLCEKAMAGEKIPVTLPQEWVPPNLRKI----KSRPGS------VSGVVSRPGSQPAS 301          

Query:   89 WSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEML 355
            W+++  E  +++ QF  L P  GF++G QAK +  +S+L   ILG+IW+LAD D DG+M+++EFSIA  LI  KL G+++P VLP  +L
Sbjct:    8 WAVTPRERLKYQEQFRALQPQAGFVTGAQAKGFFLQSQLPPLILGQIWALADTDSDGKMNINEFSIACKLINLKLRGMDVPKVLPPSLL 96          

Query: 1013 EIQSQIHQKLEKEKQRLIDLEETRLQQAVXXXXXXXXXXXXXXDRQEFLIDALAMEEEKCQMYQAKLKESLQSVESHKAHIELMRNERDELVDSTSCLFEELEAAKAEHSRCQRDRXXXXXXXXXXXXXXPFQNDLLQLENLKQLHKQSISN-LHQEIIDLQASIDLKSQNVVRNSNKLHNLENAVNCHQLAEIRRLRSNIQSKRNEVMEILEKQTQNNDVKPIFDFHQTN-----GHKLPDEFDLES-----------------------YQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLD-----PVQSNELVLTPDSETSTDK-EQNVFDQTLPDGATIKKAPNNV-WVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTE 2275
            E++++   + E EKQR  + E+ R+ +   ++ RE+E + K K     L   L+   EK +    ++ ++   V + K  I+ MR +RD  +   S L   ++   A+  +  ++R   E K      +   +N   +  N    HKQ I N +  ++ ++   I+ K +++  N  ++  L+  ++   + +   L      +R  V+E+   +     V   +D   ++     G  + D + + S                       YQA+Y+F  R  +E+TF  GDIILV  P   N   GWL G  +IN   G FP  YV+KL+     PV + E  +     T  D    N+   ++P  +    A  +V +  A +P+    E      LSF+ G+ + VI +K G+WW G + + T         G FP  YVQ  D    +  + E
Sbjct:  409 ELEAKEAARKELEKQRQQEWEQARIAEMNAQKEREQERVLKQKAHNTQLNVELSTLNEKIKELSQRICDTRAGVTNVKTVIDGMRTQRDTSMSEMSQLKARIKEQNAKLLQLTQERAKWEAKSKASGAALGGENAQQEQLNAAFAHKQLIINQIKDKVENISKEIESKKEDINTNDVQMSELKAELSAL-ITKCEDLYKEYDVQRTSVLELKYNRKNETSVSSAWDTGSSSAWEETGTTVTDPYAVASNDISALAAPAVDLGGPAPEGFVKYQAVYEFNARNAEEITFVPGDIILV--PLEQNAEPGWLAG--EINGHTGWFPESYVEKLEVGEVAPVAAVEAPVDAQVATVADTYNDNINTSSIPAASADLTAAGDVEYYIAAYPY----ESAEEGDLSFSAGEMVMVI-KKEGEWWTGTIGSRT---------GMFPSNYVQKADVGTASTAAAE 846          

Query:   62 SIMLGNQSQWSISTEEFSQHRIQFEHLNPVK-GFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPPD 367
            SI   NQ +W++   +  ++   F   +  + G+++G QA+  L +SKL    L +IW+L+D+D DGR++  EF +AM L +K + G ++P  LP+E  VPP+
Sbjct:  176 SIESVNQGEWAVQAAQKRKYTQVFNANDRTRSGYLTGSQARGVLVQSKLPQVTLAQIWTLSDIDGDGRLNCDEFILAMFLCEKAMAGEKIPVTLPQEW-VPPN 277          

Query:  566 AVRPRYRLQFNQQDRN---KKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLV 820
            AV PR RL++ +Q R    + GF++G +AK   LQS L   IL QIW L+D DSDGK+   EF +A  L+     G  +P  LP +L+
Sbjct:    9 AVTPRERLKYQEQFRALQPQAGFVTGAQAKGFFLQSQLPPLILGQIWALADTDSDGKMNINEFSIACKLINLKLRGMDVPKVLPPSLL 96          

Query: 2819 KAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNEGWVPRYCIDKEETQFIR-----DHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGD--KLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSA 3313
            K + V  ++A + +E++ +PG  + +    + +   +   ING T  GW P   ++K E   +      +   D   A+  D     I +  +   S    D    GD    IA YPY +    +LSF+   +V +I K E EWW G     S  G+FP NYV++     ++
Sbjct:  678 KYQAVYEFNARNAEEITFVPGDIILVPLEQNAEPGWLAGEINGHT--GWFPESYVEKLEVGEVAPVAAVEAPVDAQVATVADTYNDNINTSSIPAASA---DLTAAGDVEYYIAAYPYESAEEGDLSFSAGEMVMVIKK-EGEWWTG--TIGSRTGMFPSNYVQKADVGTAS 841          

Query: 2093 DQLSFNVGQRIRVIEEKSGD--WWKGEMCTHTEDDGDIYSVGWFPRIYVQ---------------PVDYSNETLLST------ESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKK--LTKQDLEHAQTIDTISSD-------YYTALSLENS-----------------NSPTM----TYDDIGRNLNDFDTDSGITDPELATPAEIGENAAYSNYCTLAXXXXXXXXXXXXXXXLSKAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNE-GWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYV 3286
            ++++F  G  I V  E++ +  W  GE+  HT         GWFP  YV+               PVD    T+  T       S++  ++ +  A+ D+                  EY +A YPYES   GDL+   G+++ ++     WW G I G+R  GMFPS+YV+K  +       A+ ++++  +        YTA  +E                   +SP +     ++D+   ++  +T S     E   PAE     +YS   +   S         ++     A+++  Y A S ++LS   GQ + I   +D  W++ +L   G   + GW P   +     + ++   N     SG +         PVS    RI+   Q  DK+IA+YPY AQN DELSF K+ I+ ++ +DEPEWWRG      + GLFP NYV
Sbjct:  691 EEITFVPGDIILVPLEQNAEPGWLAGEINGHT---------GWFPESYVEKLEVGEVAPVAAVEAPVDAQVATVADTYNDNINTSSIPAASADLTAAGDV------------------EYYIAAYPYESAEEGDLSFSAGEMVMVIKKEGEWWTGTI-GSR-TGMFPSNYVQKADVGTASTAAAEPVESLDQETTLNGNAAYTAAPVEAQEQVYQPLPVQEPSEQPISSPGVGAEEAHEDLDTEVSQINTQSKTQSSE---PAE-----SYSRPMSRTSSMTPGMRAKRSEI----AQVIAPYEATSTEQLSLTRGQLIMIRKKTDSGWWEGELQAKGRRRQIGWFPATYV-----KVLQGGRN-----SGRN--------TPVS--GSRIEMTEQILDKVIALYPYKAQNDDELSFDKDDIISVLGRDEPEWWRGE--LNGLSGLFPSNYV 1079          

Query:  542 QTDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSMVTISNNNKSLPNSHTEHEWTATSESRPGTLKAC 931
            Q +W +  A + +Y   FN  DR + G+L+G +A+ VL+QS L    LAQIW LSDID DG+L C+EF +AM+L E+A AG  +P  LP+  VPP++  I    KS P S       +   SRPG+  A 
Sbjct:  182 QGEWAVQAAQKRKYTQVFNANDRTRSGYLTGSQARGVLVQSKLPQVTLAQIWTLSDIDGDGRLNCDEFILAMFLCEKAMAGEKIPVTLPQEWVPPNLRKI----KSRPGS------VSGVVSRPGSQPAS 301          

Query:   89 WSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEML 355
            W+++  E  +++ QF  L P  GF++G QAK +  +S+L   ILG+IW+LAD D DG+M+++EFSIA  LI  KL G+++P VLP  +L
Sbjct:    8 WAVTPRERLKYQEQFRALQPQAGFVTGAQAKGFFLQSQLPPLILGQIWALADTDSDGKMNINEFSIACKLINLKLRGMDVPKVLPPSLL 96          

Query: 1013 EIQSQIHQKLEKEKQRLIDLEETRLQQAVXXXXXXXXXXXXXXDRQEFLIDALAMEEEKCQMYQAKLKESLQSVESHKAHIELMRNERDELVDSTSCLFEELEAAKAEHSRCQRDRXXXXXXXXXXXXXXPFQNDLLQLENLKQLHKQSISN-LHQEIIDLQASIDLKSQNVVRNSNKLHNLENAVNCHQLAEIRRLRSNIQSKRNEVMEILEKQTQNNDVKPIFDFHQTN-----GHKLPDEFDLES-----------------------YQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLD-----PVQSNELVLTPDSETSTDK-EQNVFDQTLPDGATIKKAPNNV-WVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTE 2275
            E++++   + E EKQR  + E+ R+ +   ++ RE+E + K K     L   L+   EK +    ++ ++   V + K  I+ MR +RD  +   S L   ++   A+  +  ++R   E K      +   +N   +  N    HKQ I N +  ++ ++   I+ K +++  N  ++  L+  ++   + +   L      +R  V+E+   +     V   +D   ++     G  + D + + S                       YQA+Y+F  R  +E+TF  GDIILV  P   N   GWL G  +IN   G FP  YV+KL+     PV + E  +     T  D    N+   ++P  +    A  +V +  A +P+    E      LSF+ G+ + VI +K G+WW G + + T         G FP  YVQ  D    +  + E
Sbjct:  409 ELEAKEAARKELEKQRQQEWEQARIAEMNAQKEREQERVLKQKAHNTQLNVELSTLNEKIKELSQRICDTRAGVTNVKTVIDGMRTQRDTSMSEMSQLKARIKEQNAKLLQLTQERAKWEAKSKASGAALGGENAQQEQLNAAFAHKQLIINQIKDKVENISKEIESKKEDINTNDVQMSELKAELSAL-ITKCEDLYKEYDVQRTSVLELKYNRKNETSVSSAWDTGSSSAWEETGTTVTDPYAVASNDISALAAPAVDLGGPAPEGFVKYQAVYEFNARNAEEITFVPGDIILV--PLEQNAEPGWLAG--EINGHTGWFPESYVEKLEVGEVAPVAAVEAPVDAQVATVADTYNDNINTSSIPAASADLTAAGDVEYYIAAYPY----ESAEEGDLSFSAGEMVMVI-KKEGEWWTGTIGSRT---------GMFPSNYVQKADVGTASTAAAE 846          

Query:   62 SIMLGNQSQWSISTEEFSQHRIQFEHLNPVK-GFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPPD 367
            SI   NQ +W++   +  ++   F   +  + G+++G QA+  L +SKL    L +IW+L+D+D DGR++  EF +AM L +K + G ++P  LP+E  VPP+
Sbjct:  176 SIESVNQGEWAVQAAQKRKYTQVFNANDRTRSGYLTGSQARGVLVQSKLPQVTLAQIWTLSDIDGDGRLNCDEFILAMFLCEKAMAGEKIPVTLPQEW-VPPN 277          

Query:  566 AVRPRYRLQFNQQDRN---KKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLV 820
            AV PR RL++ +Q R    + GF++G +AK   LQS L   IL QIW L+D DSDGK+   EF +A  L+     G  +P  LP +L+
Sbjct:    9 AVTPRERLKYQEQFRALQPQAGFVTGAQAKGFFLQSQLPPLILGQIWALADTDSDGKMNINEFSIACKLINLKLRGMDVPKVLPPSLL 96          

Query: 2819 KAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNEGWVPRYCIDKEETQFIR-----DHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGD--KLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSA 3313
            K + V  ++A + +E++ +PG  + +    + +   +   ING T  GW P   ++K E   +      +   D   A+  D     I +  +   S    D    GD    IA YPY +    +LSF+   +V +I K E EWW G     S  G+FP NYV++     ++
Sbjct:  678 KYQAVYEFNARNAEEITFVPGDIILVPLEQNAEPGWLAGEINGHT--GWFPESYVEKLEVGEVAPVAAVEAPVDAQVATVADTYNDNINTSSIPAASA---DLTAAGDVEYYIAAYPYESAEEGDLSFSAGEMVMVIKK-EGEWWTG--TIGSRTGMFPSNYVQKADVGTAS 841          

Query: 2093 DQLSFNVGQRIRVIEEKSGD--WWKGEMCTHTEDDGDIYSVGWFPRIYVQ---------------PVDYSNETLLST------ESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKK--LTKQDLEHAQTIDTISSD-------YYTALSLENS-----------------NSPTM----TYDDIGRNLNDFDTDSGITDPELATPAEIGENAAYSNYCTLAXXXXXXXXXXXXXXXLSKAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNE-GWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYV 3286
            ++++F  G  I V  E++ +  W  GE+  HT         GWFP  YV+               PVD    T+  T       S++  ++ +  A+ D+                  EY +A YPYES   GDL+   G+++ ++     WW G I G+R  GMFPS+YV+K  +       A+ ++++  +        YTA  +E                   +SP +     ++D+   ++  +T S     E   PAE     +YS   +   S         ++     A+++  Y A S ++LS   GQ + I   +D  W++ +L   G   + GW P   +     + ++   N     SG +         PVS    RI+   Q  DK+IA+YPY AQN DELSF K+ I+ ++ +DEPEWWRG      + GLFP NYV
Sbjct:  687 EEITFVPGDIILVPLEQNAEPGWLAGEINGHT---------GWFPESYVEKLEVGEVAPVAAVEAPVDAQVATVADTYNDNINTSSIPAASADLTAAGDV------------------EYYIAAYPYESAEEGDLSFSAGEMVMVIKKEGEWWTGTI-GSR-TGMFPSNYVQKADVGTASTAAAEPVESLDQETTLNGNAAYTAAPVEAQEQVYQPLPVQEPSEQPISSPGVGAEEAHEDLDTEVSQINTQSKTQSSE---PAE-----SYSRPMSRTSSMTPGMRAKRSEI----AQVIAPYEATSTEQLSLTRGQLIMIRKKTDSGWWEGELQAKGRRRQIGWFPATYV-----KVLQGGRN-----SGRN--------TPVS--GSRIEMTEQILDKVIALYPYKAQNDDELSFDKDDIISVLGRDEPEWWRGE--LNGLSGLFPSNYV 1075          

Query:  542 QTDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSMVTISNNNKSLPNSHTEHEWTATSESRPGTLKAC 931
            Q +W +  A + +Y   FN  DR + G+L+G +A+ VL+QS L    LAQIW LSDID DG+L C+EF +AM+L E+A AG  +P  LP+  VPP++  I    KS P S       +   SRPG+  A 
Sbjct:  182 QGEWAVQAAQKRKYTQVFNANDRTRSGYLTGSQARGVLVQSKLPQVTLAQIWTLSDIDGDGRLNCDEFILAMFLCEKAMAGEKIPVTLPQEWVPPNLRKI----KSRPGS------VSGVVSRPGSQPAS 301          

Query:   89 WSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEML 355
            W+++  E  +++ QF  L P  GF++G QAK +  +S+L   ILG+IW+LAD D DG+M+++EFSIA  LI  KL G+++P VLP  +L
Sbjct:    8 WAVTPRERLKYQEQFRALQPQAGFVTGAQAKGFFLQSQLPPLILGQIWALADTDSDGKMNINEFSIACKLINLKLRGMDVPKVLPPSLL 96          

Query: 1013 EIQSQIHQKLEKEKQRLIDLEETRLQQAVXXXXXXXXXXXXXXDRQEFLIDALAMEEEKCQMYQAKLKESLQSVESHKAHIELMRNERDELVDSTSCLFEELEAAKAEHSRCQRDRXXXXXXXXXXXXXXPFQNDLLQLENLKQLHKQSISN-LHQEIIDLQASIDLKSQNVVRNSNKLHNLENAVNCHQLAEIRRLRSNIQSKRNEVMEILEKQTQNNDVKPIFDFHQTN-----GHKLPDEFDLES-----------------------YQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLD-----PVQSNELVLTPDSETSTDK-EQNVFDQTLPDGATIKKAPNNV-WVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTE 2275
            E++++   + E EKQR  + E+ R+ +   ++ RE+E + K K     L   L+   EK +    ++ ++   V + K  I+ MR +RD  +   S L   ++   A+  +  ++R   E K      +   +N   +  N    HKQ I N +  ++ ++   I+ K +++  N  ++  L+  ++   + +   L      +R  V+E+   +     V   +D   ++     G  + D + + S                       YQA+Y+F  R  +E+TF  GDIILV  P   N   GWL G  +IN   G FP  YV+KL+     PV + E  +     T  D    N+   ++P  +    A  +V +  A +P+    E      LSF+ G+ + VI +K G+WW G + + T         G FP  YVQ  D    +  + E
Sbjct:  405 ELEAKEAARKELEKQRQQEWEQARIAEMNAQKEREQERVLKQKAHNTQLNVELSTLNEKIKELSQRICDTRAGVTNVKTVIDGMRTQRDTSMSEMSQLKARIKEQNAKLLQLTQERAKWEAKSKASGAALGGENAQQEQLNAAFAHKQLIINQIKDKVENISKEIESKKEDINTNDVQMSELKAELSAL-ITKCEDLYKEYDVQRTSVLELKYNRKNETSVSSAWDTGSSSAWEETGTTVTDPYAVASNDISALAAPAVDLGGPAPEGFVKYQAVYEFNARNAEEITFVPGDIILV--PLEQNAEPGWLAG--EINGHTGWFPESYVEKLEVGEVAPVAAVEAPVDAQVATVADTYNDNINTSSIPAASADLTAAGDVEYYIAAYPY----ESAEEGDLSFSAGEMVMVI-KKEGEWWTGTIGSRT---------GMFPSNYVQKADVGTASTAAAE 842          

Query:   62 SIMLGNQSQWSISTEEFSQHRIQFEHLNPVK-GFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPPD 367
            SI   NQ +W++   +  ++   F   +  + G+++G QA+  L +SKL    L +IW+L+D+D DGR++  EF +AM L +K + G ++P  LP+E  VPP+
Sbjct:  176 SIESVNQGEWAVQAAQKRKYTQVFNANDRTRSGYLTGSQARGVLVQSKLPQVTLAQIWTLSDIDGDGRLNCDEFILAMFLCEKAMAGEKIPVTLPQEW-VPPN 277          

Query:  566 AVRPRYRLQFNQQDRN---KKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLV 820
            AV PR RL++ +Q R    + GF++G +AK   LQS L   IL QIW L+D DSDGK+   EF +A  L+     G  +P  LP +L+
Sbjct:    9 AVTPRERLKYQEQFRALQPQAGFVTGAQAKGFFLQSQLPPLILGQIWALADTDSDGKMNINEFSIACKLINLKLRGMDVPKVLPPSLL 96          

Query: 2819 KAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNEGWVPRYCIDKEETQFIR-----DHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGD--KLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSA 3313
            K + V  ++A + +E++ +PG  + +    + +   +   ING T  GW P   ++K E   +      +   D   A+  D     I +  +   S    D    GD    IA YPY +    +LSF+   +V +I K E EWW G     S  G+FP NYV++     ++
Sbjct:  674 KYQAVYEFNARNAEEITFVPGDIILVPLEQNAEPGWLAGEINGHT--GWFPESYVEKLEVGEVAPVAAVEAPVDAQVATVADTYNDNINTSSIPAASA---DLTAAGDVEYYIAAYPYESAEEGDLSFSAGEMVMVIKK-EGEWWTG--TIGSRTGMFPSNYVQKADVGTAS 837          

Query: 1013 EIQSQIHQKLEKEKQRLIDLEETRLQQAVXXXXXXXXXXXXXXDRQEFLIDALAMEEEKCQMYQAKLKESLQSVESHKAHIELMRNERDELVDSTSCLFEELEAAKAEHSRCQRDRXXXXXXXXXXXXXXPFQNDLLQLENLKQLHKQSISN-LHQEIIDLQASIDLKSQNVVRNSNKLHNLENAVNCHQLAEIRRLRSNIQSKRNEVMEILEKQTQNNDVKPIFDFHQTN-----GHKLPDEFDLES-----------------------YQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLD-----PVQSNELVLTPDSETSTDK-EQNVFDQTLPDGATIKKAPNNV-WVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMS-THWWKGHIRGA---RENGMFPSHYVKKL 2545
            E++++   + E EKQR  + E+ R+ +   ++ RE+E + K K     L   L+   EK +    ++ ++   V + K  I+ MR +RD  +   S L   ++   A+  +  ++R   E K      +   +N   +  N    HKQ I N +  ++ ++   I+ K +++  N  ++  L+  ++   + +   L      +R  V+E+   +     V   +D   ++     G  + D + + S                       YQA+Y+F  R  +E+TF  GDIILV  P   N   GWL G  +IN   G FP  YV+KL+     PV + E  +     T  D    N+   ++P  +    A  +V +  A +P+    E      LSF+ G+ + VI +K G+WW G + + T         G FP  YVQ  D    +  + E          A  ++I                       + PYE+T    L++  G +I I   + + WW+G ++     R+ G FP+ YVK L
Sbjct:  409 ELEAKEAARKELEKQRQQEWEQARIAEMNAQKEREQERVLKQKAHNTQLNVELSTLNEKIKELSQRICDTRAGVTNVKTVIDGMRTQRDTSMSEMSQLKARIKEQNAKLLQLTQERAKWEAKSKASGAALGGENAQQEQLNAAFAHKQLIINQIKDKVENISKEIESKKEDINTNDVQMSELKAELSAL-ITKCEDLYKEYDVQRTSVLELKYNRKNETSVSSAWDTGSSSAWEETGTTVTDPYAVASNDISALAAPAVDLGGPAPEGFVKYQAVYEFNARNAEEITFVPGDIILV--PLEQNAEPGWLAG--EINGHTGWFPESYVEKLEVGEVAPVAAVEAPVDAQVATVADTYNDNINTSSIPAASADLTAAGDVEYYIAAYPY----ESAEEGDLSFSAGEMVMVI-KKEGEWWTGTIGSRT---------GMFPSNYVQKADVGTASTAAAEPVESLDQGMRAKRSEI--------------------AQVIAPYEATSTEQLSLTRGQLIMIRKKTDSGWWEGELQAKGRRRQIGWFPATYVKVL 920          

Query:  542 QTDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSMVTISNNNKSLPNSHTEHEWTATSESRPGTLKAC 931
            Q +W +  A + +Y   FN  DR + G+L+G +A+ VL+QS L    LAQIW LSDID DG+L C+EF +AM+L E+A AG  +P  LP+  VPP++  I    KS P S       +   SRPG+  A 
Sbjct:  182 QGEWAVQAAQKRKYTQVFNANDRTRSGYLTGSQARGVLVQSKLPQVTLAQIWTLSDIDGDGRLNCDEFILAMFLCEKAMAGEKIPVTLPQEWVPPNLRKI----KSRPGS------VSGVVSRPGSQPAS 301          

Query: 2390 ALYPYESTVPGDLTMRPGDIIQI---VDMSTHWWKGHIRGARENGMFPSHYVKKL------------TKQDLEHAQTIDTISSDYYTALSLENSNSPTMTYDDIGRNLNDF------DTDSGITDPELAT---------PAEIGENAAY--SNYCTLAXXXXXXXXXXXXXXXLSK---------AKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNE-GWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYV 3286
            A+Y + +    ++T  PGDII +    +    W  G I G    G FP  YV+KL               D + A   DT + +  T+ S+  +++      D+   +  +      + D   +  E+              IG       SNY   A+      +      SL +         A+++  Y A S ++LS   GQ + I   +D  W++ +L   G   + GW P   +     + ++   N     SG +         PVS    RI+   Q  DK+IA+YPY AQN DELSF K+ I+ ++ +DEPEWWRG      + GLFP NYV
Sbjct:  681 AVYEFNARNAEEITFVPGDIILVPLEQNAEPGWLAGEING--HTGWFPESYVEKLEVGEVAPVAAVEAPVDAQVATVADTYNDNINTS-SIPAASADLTAAGDVEYYIAAYPYESAEEGDLSFSAGEMVMVIKKEGEWWTGTIGSRTGMFPSNYVQKADVGTASTAAAEPVESLDQGMRAKRSEIAQVIAPYEATSTEQLSLTRGQLIMIRKKTDSGWWEGELQAKGRRRQIGWFPATYV-----KVLQGGRN-----SGRN--------TPVS--GSRIEMTEQILDKVIALYPYKAQNDDELSFDKDDIISVLGRDEPEWWRGE--LNGLSGLFPSNYV 996          

Query:   89 WSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEML 355
            W+++  E  +++ QF  L P  GF++G QAK +  +S+L   ILG+IW+LAD D DG+M+++EFSIA  LI  KL G+++P VLP  +L
Sbjct:    8 WAVTPRERLKYQEQFRALQPQAGFVTGAQAKGFFLQSQLPPLILGQIWALADTDSDGKMNINEFSIACKLINLKLRGMDVPKVLPPSLL 96          

Query:   62 SIMLGNQSQWSISTEEFSQHRIQFEHLNPVK-GFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPPD 367
            SI   NQ +W++   +  ++   F   +  + G+++G QA+  L +SKL    L +IW+L+D+D DGR++  EF +AM L +K + G ++P  LP+E  VPP+
Sbjct:  176 SIESVNQGEWAVQAAQKRKYTQVFNANDRTRSGYLTGSQARGVLVQSKLPQVTLAQIWTLSDIDGDGRLNCDEFILAMFLCEKAMAGEKIPVTLPQEW-VPPN 277          

Query:  566 AVRPRYRLQFNQQDRN---KKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLV 820
            AV PR RL++ +Q R    + GF++G +AK   LQS L   IL QIW L+D DSDGK+   EF +A  L+     G  +P  LP +L+
Sbjct:    9 AVTPRERLKYQEQFRALQPQAGFVTGAQAKGFFLQSQLPPLILGQIWALADTDSDGKMNINEFSIACKLINLKLRGMDVPKVLPPSLL 96          

Query: 2819 KAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNEGWVPRYCIDKEETQFIR-----DHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGD--KLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSA 3313
            K + V  ++A + +E++ +PG  + +    + +   +   ING T  GW P   ++K E   +      +   D   A+  D     I +  +   S    D    GD    IA YPY +    +LSF+   +V +I K E EWW G     S  G+FP NYV++     ++
Sbjct:  678 KYQAVYEFNARNAEEITFVPGDIILVPLEQNAEPGWLAGEINGHT--GWFPESYVEKLEVGEVAPVAAVEAPVDAQVATVADTYNDNINTSSIPAASA---DLTAAGDVEYYIAAYPYESAEEGDLSFSAGEMVMVIKK-EGEWWTG--TIGSRTGMFPSNYVQKADVGTAS 841          

Query: 1598 LRSNIQSKRNEVMEILEKQTQNNDVKPIFDFHQTNGHKLPDEFDLESYQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNVFDQTLPD-GATIKKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDW------WKGEMCTHTEDDGDIYSVGW--FPRIYVQP-VDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQTIDTISSDYYTALSL--------------ENSNSPTM----------TYDDIGRNLNDFDTDSGIT----DPELATPAEIGENAAY-SNYCTLAXXXXXXXXXXXXXXXLSK----AKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNE-GWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGM----QPGD--KLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLL--VTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLI-MAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIR--RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFF 4957
            +R N++++    + +L+K        P+  F+Q       ++  +  Y+A+Y F  R  DE+T   GDI++V + S    P GWL G +K     G FP  Y +K+           P+SE       +    + P  G+ +  A ++     I P   +     P   +             S +W      W        +D     S GW  +P    QP +   +   +   S    + L+ ++ + + G               G    ALYP+ +     L     D+I +++    WW G ++G R  G FP  YVK L    +  + +I++ SSD   ++                +NSNS +M          TY+   +    F     IT    + +  T    G+   + SNY  +         +     SL K    A+++  Y+A   ++L+  PGQ + I   +   W++ +L   G   + GW P                      + Y + L+     P + ++   D        P    ++I MY Y+AQN DEL F K  I+ ++S+++P+WW+G       +GLFP NYV+      + D         +PS +              W  D  ++   +LT  E++RQ YI ELI TE+ Y  DLQ V   F +P+ +S+LLT +E+  IF+NW +L   +     AL++RK  SG + P++ +GDIL +  P+   Y+RFCS Q     L+++K     +FK+F ++   + RCK MP+SS+ LKPMQR+T+Y LI++NIL+NT + HPD   +  A+  A  LC  VNEG+REKENS+RLEWIQ HVQC+GL+E+L FNS TN LG RK ++SG LYKAKS KEL GFLFNDFLLL  +     ++G   VF    S+   +Q++MYK PI LN VL+ +   PS                      IF I      + ++A S+N+R  WV+++ AAS  +IETE   RE +  +R  R+ G+GRL+V ++EG  LK   +   K++ YCE ++G+Q   TK +  T NPKWN + QF IK++E DVLC++ ++++ F+P+DFLGRTE+ L DIK+ +  +KGPI +RL L  V +GE++V+LDL  F
Sbjct:  674 MRVNVRNQHKSCVCVLDK-------IPVSGFNQ-------EKVKVVYYRAMYPFEARSHDEITIHPGDIVMV-DESQTGEP-GWLGGEIKGKT--GWFPANYAEKI-----------PESEVPLSLRASAASSSAPKLGSHMSSASSSTTATPILPVSTEPASIAPPSSAPPPTGPASSSSSASSNWADFSTTWPSNSAVEKQD-----SDGWDAWPTQPTQPSLSVPSGGQIRQRSAFTPATLSGSSPSPVLG---------QGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDMWWFGEVQGQR--GWFPKSYVK-LISGPVRKSMSIESGSSDSPPSVKRPSPSLNKPTELGEGQNSNSNSMYPSKEYVAMYTYESNEQGDLTFQQGDVITVTKKEGDWWTGTVSGKIGVFPSNY--VKPKESEGLGSAGKTGSLGKKPEIAQVIAPYTATGAEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFP----------------------ANYVKLLS-----PSTSKTTPTDPNPPKLPTPNAVCQVIGMYDYTAQNDDELPFGKGQIINVLSREDPDWWKGE--LNGSVGLFPSNYVK-----LTTDT--------DPSQQ--------------WCAD--LHLLDMLTPVERKRQGYIHELIVTEENYVNDLQLVTETFQKPLLESDLLTEKEVAMIFVNWKELTMCNIKLLKALRVRKKMSGERMPVKMIGDILTAQLPHMQPYIRFCSCQLNGATLIQQKTDEVPEFKDFVKRLAMDPRCKGMPLSSFLLKPMQRVTRYPLIIKNILENTPESHPDHSHLRLALEKAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQIIKPLGSSGTDKVF----SAKSHLQYRMYKTPIFLNEVLVKLPTDPSGDE------------------PIFHISHIDRVYTIRAESINERTAWVQKIKAASELFIETEKRKREKAYLVRSQRATGIGRLMVNIVEGIELKPCRS-NGKSNPYCEVTMGSQCHVTKTLQDTLNPKWNSNCQFFIKDLEQDVLCVTVFERDQFSPDDFLGRTEIRLADIKKDQ-GSKGPITKRLLLHEVPTGEIVVRLDLQLF 1718          

Query:   74 GNQSQWSISTEEFSQHRIQFEHLNPV-KGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEM------LVPPDSFPFSDLGANEIFSSKAAPSYNEVMAKDKADRQ----------------SFREKPPIPQDIQSTFPPLPKRTSPQTDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAG 784
            G    W IS +E ++H  QF  L P   GFI+G QA+ +  +S L   IL +IW+LAD++ DG+M +HEFSIAM LIK KL+G  LP  LP  M      + PP  F    +G +    +   P    +     A  Q                SF       Q  QS   P      P  DW + Q+ R +YR  FN  D+   G+L+G +A+ +L+QS L  + LA IWNLSDID DGKLT EEF +AM+L++ A +G
Sbjct:   10 GGSDTWVISVDERAKHDQQFHSLTPTPAGFITGDQARNFFLQSGLPAPILAQIWALADMNNDGKMDMHEFSIAMKLIKLKLQGHPLPPSLPPSMKQQPISIPPPTPFGVPGMGVSPPLGASVTPPVPSLANGAPAMIQPLSGFSHPGAVLNKTPSFNRSSIKLQKGQSVEAPSAPAAPPPADWAVSQSSRLKYRQLFNSHDKMMSGYLTGPQARTILMQSSLPQAQLATIWNLSDIDQDGKLTAEEFILAMHLIDMAMSG 269          

Query: 2375 GEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQTIDTISSDYYTALSL--------------ENSNSPTM----------TYDDIGRNLNDFDTDSGIT----DPELATPAEIGENAAY-SNYCTLAXXXXXXXXXXXXXXXLSK----AKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNE-GWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGM----QPGD--KLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLL--VTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLI-MAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIR--RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFF 4957
            G    ALYP+ +     L     D+I +++    WW G ++G R  G FP  YVK L    +  + +I++ SSD   ++                +NSNS +M          TY+   +    F     IT    + +  T    G+   + SNY  +         +     SL K    A+++  Y+A   ++L+  PGQ + I   +   W++ +L   G   + GW P                      + Y + L+     P + ++   D        P    ++I MY Y+AQN DEL F K  I+ ++S+++P+WW+G       +GLFP NYV+      + D         +PS +              W  D  ++   +LT  E++RQ YI ELI TE+ Y  DLQ V   F +P+ +S+LLT +E+  IF+NW +L   +     AL++RK  SG + P++ +GDIL +  P+   Y+RFCS Q     L+++K     +FK+F ++   + RCK MP+SS+ LKPMQR+T+Y LI++NIL+NT + HPD   +  A+  A  LC  VNEG+REKENS+RLEWIQ HVQC+GL+E+L FNS TN LG RK ++SG LYKAKS KEL GFLFNDFLLL  +     ++G   VF    S+   +Q++MYK PI LN VL+ +   PS                      IF I      + ++A S+N+R  WV+++ AAS  +IETE   RE +  +R  R+ G+GRL+V ++EG  LK   +   K++ YCE ++G+Q   TK +  T NPKWN + QF IK++E DVLC++ ++++ F+P+DFLGRTE+ L DIK+ +  +KGPI +RL L  V +GE++V+LDL  F
Sbjct:  901 GLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDMWWFGEVQGQR--GWFPKSYVK-LISGPVRKSMSIESGSSDSPPSVKRPSPSLNKPTELGEGQNSNSNSMYPSKEYVAMYTYESNEQGDLTFQQGDVITVTKKEGDWWTGTVSGKIGVFPSNY--VKPKESEGLGSAGKTGSLGKKPEIAQVIAPYTATGAEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFP----------------------ANYVKLLS-----PSTSKTTPTDPNPPKLPTPNAVCQVIGMYDYTAQNDDELPFGKGQIINVLSREDPDWWKGE--LNGSVGLFPSNYVK-----LTTDT--------DPSQQ--------------WCAD--LHLLDMLTPVERKRQGYIHELIVTEENYVNDLQLVTETFQKPLLESDLLTEKEVAMIFVNWKELTMCNIKLLKALRVRKKMSGERMPVKMIGDILTAQLPHMQPYIRFCSCQLNGATLIQQKTDEVPEFKDFVKRLAMDPRCKGMPLSSFLLKPMQRVTRYPLIIKNILENTPESHPDHSHLRLALEKAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQIIKPLGSSGTDKVF----SAKSHLQYRMYKTPIFLNEVLVKLPTDPSGDE------------------PIFHISHIDRVYTIRAESINERTAWVQKIKAASELFIETEKRKREKAYLVRSQRATGIGRLMVNIVEGIELKPCRS-NGKSNPYCEVTMGSQCHVTKTLQDTLNPKWNSNCQFFIKDLEQDVLCVTVFERDQFSPDDFLGRTEIRLADIKKDQ-GSKGPITKRLLLHEVPTGEIVVRLDLQLF 1719          

Query:   74 GNQSQWSISTEEFSQHRIQFEHLNPV-KGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEM------LVPPDSFPFSDLGANEIFSSKAAPSYNEVMAKDKADRQ----------------SFREKPPIPQDIQSTFPPLPKRTSPQTDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAG 784
            G    W IS +E ++H  QF  L P   GFI+G QA+ +  +S L   IL +IW+LAD++ DG+M +HEFSIAM LIK KL+G  LP  LP  M      + PP  F    +G +    +   P    +     A  Q                SF       Q  QS   P      P  DW + Q+ R +YR  FN  D+   G+L+G +A+ +L+QS L  + LA IWNLSDID DGKLT EEF +AM+L++ A +G
Sbjct:   10 GGSDTWVISVDERAKHDQQFHSLTPTPAGFITGDQARNFFLQSGLPAPILAQIWALADMNNDGKMDMHEFSIAMKLIKLKLQGHPLPPSLPPSMKQQPISIPPPTPFGVPGMGVSPPLGASVTPPVPSLANGAPAMIQPLSGFSHPGAVLNKTPSFNRSSIKLQKGQSVEAPSAPAAPPPADWAVSQSSRLKYRQLFNSHDKMMSGYLTGPQARTILMQSSLPQAQLATIWNLSDIDQDGKLTAEEFILAMHLIDMAMSG 269          

Query: 2045 VEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIX----XXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQTIDTISSD--------YYTALSLENSNSPTMTYDDIGRNLNDFDTDSGITDPELATPAEIGENAAY-SNYCTLAXXXXXXXXXXX-------XXXXLSKAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTN 2956
             +A++PW    ++     L+FN    I V+E++   WW GE+             GWFP+ YV+ +       +S ES    S  +    +     P       N+++     S EY +A+Y YES   GDLT + GD+I +      WW G + G  + G+FPS+YVK    + L  A    ++            YTA   E      +T       L       G  + EL    +  +   + +NY  L   S  + +            N++ +   +  Y+A + DEL    GQ +N++   D DW+K +L  NGS  
Sbjct:  904 AQALYPWRAKKDN----HLNFNKNDVITVLEQQDM-WWFGEVQGQR---------GWFPKSYVKLISGPVRKSMSIESGSSDSPPSVKRPSPSLNKPTELGEGQNSNSNSMYPSKEY-VAMYTYESNEQGDLTFQQGDVITVTKKEGDWWTGTVSG--KIGVFPSNYVKPKESEGLGSAGKTGSLGKKPEIAQVIAPYTATGAEQ-----LTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLLSPSTSKTTPTDPNPPKLPTPNAVCQVIGMYDYTAQNDDELPFGKGQIINVLSREDPDWWKGEL--NGSVG 1203          

Query: 1733 ESYQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNVFDQTLPDGATIKKAPN-NVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQ 2236
            E  Q +  +     ++LT   G +IL+R  +P     G L  R K  Q  G FP  YVK L P  S                     +T P      K P  N   + I  +   A+++  D+L F  GQ I V+  +  DWWKGE+           SVG FP  YV+
Sbjct: 1076 EIAQVIAPYTATGAEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQI-GWFPANYVKLLSPSTS---------------------KTTPTDPNPPKLPTPNAVCQVIGMYDYTAQND--DELPFGKGQIINVLSREDPDWWKGELNG---------SVGLFPSNYVK 1211          

Query: 2003 PDGATIKKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIE--EKSGDW----WKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQTIDTISSDYYTALSLENSNSPTMTYDDIGRNLNDFDTDSGITDPELATPAEIGENAAYSNYCTLAXXXXXXXXXXXXXXXLSKAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNE-GWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLLVTP--SYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLI-MAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIR--RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFFRY 4963
            P G   +++      +A++P+    E+E    LSF     I V E  E+   W    W+G+M             GWFP  YV+    S   +++ ++     +++ ++++           S T   S+ E  +ALY YES  PGDLT   GD I + +    WW+G I G R  G+FPS+YVK                                              +TD+     +  TP +  E A  +  CT                            A   ++L+  PGQ + I++ +   W+  +L   G   + GW P              H   L + SG         S P +    ++          IA+Y Y+A N DELSF+K+ ++ ++ K  P+WW+G      + GL P NYV+      + D         +PS +     ST+                  ++  +++RQ YI ELI+TE+ Y EDLQ V  VFY+P+ +SN L+  E+  IF NW +LI  S     ALK RK + G+  P+  +GDIL S   N   Y+RFCS Q +  ALL+++      FK F ++   + RCK MP+SS+ LKPMQRIT+Y L +++IL+NT + H D   + EA+  A  LC  VNEG+REKENS+RLEWIQ HVQC+G+ E L FNS TN LG RKL++SG ++K KS KEL  FLF+DFLL       + ++G   +F    S     Q+KMYK P+ LN VL+ +   PS                  S   +F I      + LK  ++N+R  WV+++  AS  +IETE    E +   R  + +G+GRLLVT+LE   LKSS  P  K++ YCE ++G+Q   ++ ++ T NPKWN + QF IK++  DVLC++  +KE F+P+ FLGRTEV +  IK+ +L NKGP  RRL L  V +GE+ V+LDL  F +
Sbjct:  925 PLGTQHRRSAALTTFKALYPFTARNEEE----LSFESDDLIEVDESVEREQGWLYGSWQGKM-------------GWFPESYVEKQTKSEAPVVAKQALKPQVSISVSSTD----------ASDTTDGSNYEEYVALYTYESPEPGDLTFNEGDTILVSEREGEWWRGSI-GDRA-GLFPSNYVKPK--------------------------------------------ETDTSSLSGKSGTPGKKPEVAQVTTACT----------------------------AAGAEQLNLSPGQLILILNKNPSGWWLGELQARGKKRQKGWFP------------ASHVKLLGSNSGK--------STPATPSVGQV----------IAIYDYTAANEDELSFSKSQVINVLDKSNPDWWKGE--LNGVTGLIPTNYVK-----LTTDS--------DPSQQWCADQSTLES----------------MSPKDRKRQDYIHELIDTEEKYVEDLQLVLEVFYKPMSESNRLSEAEMNMIFANWRELIQCSSKMLKALKARKKSGGDNMPVHMIGDILTSELSNMQAYIRFCSCQLEGAALLQQRTDQEPDFKTFLKKIATDYRCKGMPLSSFLLKPMQRITRYPLHIKHILENTPESHVDYIQLTEALEKAELLCFEVNEGVREKENSDRLEWIQSHVQCEGIAENLIFNSMTNCLGPRKLLHSGKVFKMKSNKELHAFLFSDFLLFTQAVRQFTSSGTDKLF----SPKSNTQYKMYKTPVFLNEVLVKLPSDPS------------------SDEPVFHISHIDRVYTLKTENINERTAWVQKIKVASEGFIETEKKKHEKAYQSRSMKGSGIGRLLVTILEATELKSSK-PNGKSNPYCEVTMGSQCYTSRTINDTVNPKWNFNCQFHIKDLYQDVLCITINEKELFSPDAFLGRTEVPVATIKK-ELENKGPSTRRLLLHEVPTGEVWVRLDLQLFDH 1737          

Query:  545 TDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSM 832
            +DW + QA R +YR QFN  D+   G+L+G + +  +  + L+ + LA IWNL+D+D DGKL  +EF +AM+LV+ A+ G+ LP  LP  LVPPS+
Sbjct:  231 SDWGVPQASRLKYRQQFNSLDKLMSGYLTGPQVRTAMATTLLTQTQLAAIWNLADVDKDGKLKADEFILAMHLVDMAKMGQPLPLALPSDLVPPSL 326          

Query:   68 MLGNQSQWSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLP---KEMLVPPDSFPFSDLG 391
            M G +S W+I+ EE  +H  +F+ L P +G+++G +A+ +  +S L   +L  IW+LAD+++DG+M   EFSIAM LIK KL+G  LP  LP   K+  VP  + P + LG
Sbjct:    1 MNGGRSIWAITPEERDKHDQKFDSLLPAQGYVTGEKARNFFIQSGLPQPVLAAIWALADMNKDGKMDRLEFSIAMKLIKMKLQGQNLPTALPIIMKQPPVPAPTMPAAPLG 111          

Query: 1583 AEIRRLRSNIQSKRNEVMEILEK------QTQNNDVKPIFDFHQTNGHKLPDEFDLESYQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNVFDQTLPDGATIKKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMS-THWWKGHI--RG-ARENGMFPSHYVKKL 2545
            A   RLR + Q+K+N V   L        + +    +P+   H+ +         L +++ALY F  R  +EL+FE+ D+I V          GWL G  +     G FP  YV+K    ++      P       K Q     +  D +      N     A++ +    E   P  L+FN G  I ++ E+ G+WW+G +       GD    G FP  YV+P + ++ + LS +S                G P         + +    C A    +      L + PG +I I++ + + WW G +  RG  R+ G FP+ +VK L
Sbjct:  888 AAAARLRDDEQNKKNTVKSDLVSALLRGLEERKGGRRPLGTQHRRSAA-------LTTFKALYPFTARNEEELSFESDDLIEVDE--SVEREQGWLYGSWQGK--MGWFPESYVEKQTKSEA------PVVAKQALKPQVSISVSSTDASDTTDGSNYEEYVALYTY----ESPEPGDLTFNEGDTI-LVSEREGEWWRGSI-------GD--RAGLFPSNYVKPKE-TDTSSLSGKS----------------GTPGKKPEVAQVTTA----CTAAGAEQ------LNLSPGQLILILNKNPSGWWLGELQARGKKRQKGWFPASHVKLL 1160          

Query:   74 GNQSQWSISTEEFSQHRIQFEHLNPV-KGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPP 364
            G  S W +      ++R QF  L+ +  G+++G Q +  +  + L+   L  IW+LADVD+DG++   EF +AMHL+     G  LP  LP + LVPP
Sbjct:  228 GGPSDWGVPQASRLKYRQQFNSLDKLMSGYLTGPQVRTAMATTLLTQTQLAAIWNLADVDKDGKLKADEFILAMHLVDMAKMGQPLPLALPSD-LVPP 324          

Query:  551 WVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETL----VP-PSMVTISNNNKSLPN 868
            W I    R ++  +F+      +G+++G++A+   +QSGL   +LA IW L+D++ DGK+   EF +AM L++    G+ LP+ LP  +    VP P+M        ++PN
Sbjct:    8 WAITPEERDKHDQKFDSL-LPAQGYVTGEKARNFFIQSGLPQPVLAAIWALADMNKDGKMDRLEFSIAMKLIKMKLQGQNLPTALPIIMKQPPVPAPTMPAAPLGMGAMPN 117          

Query: 2210 GWFPRIYVQPVDYSNET---LLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQD---------LEHAQTIDTISSDYYTAL-SLENSNSPTMTYDDIGRNLNDFDTDSGITDPELATPAE-------IGENAAY--SNYCTLAXXXXXXXXXXXXXXXLSKAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGST-NEGWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLLVTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLI-MAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIR--RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFF 4957
            GWFP  Y +     ++T      TEST   +N       DI G P   +T  + +    +  +AL  + +     L     DII +++   +WW G ++  R  G FP  +V  +T  +         +E  +  D+   D Y AL + E+  S  +T+                 D  L T  E       IG+      SNY    E      +  S +  +  A++     A + ++LS  PGQ + ++  +   W+  +L   G    +GW            F   +   L   SG                  +I    QP  ++IAMY Y A N DE+SF K  ++ +++KD P+WW+G      + GLFP NYV+   T C            +PS +              W  D +++ +++ TE E++RQ YI ELI+TE++Y EDL+    VFY+P+ +S  LT  E+  IF+NW +LI  S     AL++RK  +G + P+Q VGDIL S   +   Y+RFCS Q  A ALL++K   S  FK F ++   N RCK MP+SS+ LKPMQRIT+Y L+++NIL+NT   H D  +++ A+  A  LC  VNE +REKENS+RLEWIQ+HV CDG+ E L FNS TN LG RKL++SG L+K KS KEL   LFNDFLLL   S   +  P       S++   Q+KMYK P+ LN VL+ M   PS                  S   +F I      + LK  ++N+R  WV+++ AAS  +IETE   RE +   R  +++G+GRLLVTVLE   LK    P  K++ YCE ++G Q   ++    T NPKW+ + QF IK++  DVLCL+ ++++ F+P+DFLGRTEV +  IK+ +   KGP+ RRL L  V +GE+ V+LDL  +
Sbjct:  796 GWFPESYAERCSKDSQTQPTAAETESTAPSANYPGIPRVDIEG-PTPTHTPVSTNTQHSQ-AVALCEWSAKTDSHLGFCKDDIITVLEKQENWWYGELKEKR--GWFPCSHVSVVTTNNTQSEPLYSSVEEIEVSDSGLLDEYVALYTYESPESGDLTF--------------SAEDVVLVTEKEGEWWRGCIGDQTGLFPSNYVKPKEPDTASSAVPSKKPEI--AQVTTVSPATTPEQLSLTPGQLIVVLHKNSNSWWLGELQARGKKRKKGW------------FQSSNVRLLEANSG------------------KITPAPQPLCQVIAMYDYKAANKDEMSFQKGQLITVLNKDNPDWWKGE--VAGVTGLFPTNYVKM-TTEC------------DPSQQ--------------WCAD-LLSLDSMCTE-ERKRQGYIHELIQTEESYLEDLELAVEVFYKPMAESGRLTEAEISMIFVNWRELIMCSTKLLKALRVRKKTAGERMPVQVVGDILSSELSHMQAYIRFCSCQLNAAALLQQKTDKSLDFKLFLKKIASNYRCKGMPLSSFLLKPMQRITRYPLLIKNILENTPPAHADHSNLQAALEQAEELCSQVNEAVREKENSDRLEWIQNHVLCDGVIEHLVFNSLTNCLGPRKLLHSGKLHKTKSSKELWALLFNDFLLLTYTSKQFSSSPDKLFNPNSNT---QYKMYKTPVFLNEVLVKMPSDPS------------------SDDPVFHISHIDRVYTLKTDTINERTTWVQKIKAASDHFIETEKLKREKAYQARSQKNSGIGRLLVTVLEATELKPCK-PNGKSNPYCELTMGAQCYTSRHQPDTLNPKWSFNCQFFIKDLYQDVLCLTVFERDQFSPDDFLGRTEVPVATIKKDQ-DGKGPLVRRLLLHEVPTGEVKVRLDLQLY 1633          

Query:   68 MLGNQSQWSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLP 343
            M G  S W+I+ EE  +H  QF+ L P  G++SG QA+++  +S L   +L  IW+LAD+ +DG+M   EFSIAM LIK +L+G  LP+ LP
Sbjct:    1 MNGGFSIWAITPEERGKHDKQFDSLAPTLGYLSGDQARKFFLQSGLPTSVLADIWALADIGKDGKMDRLEFSIAMKLIKLQLQGQPLPSSLP 92          

Query: 1655 TQNNDVKPIFDFHQTNGHKLPDEFDLESYQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNVFDQTLPDGATIKKAP---NNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVK 2539
            T+NN ++P+     T          L +Y+ALY F  R +DELT EA   I V   +   T  GWL G    N+  G FP  Y ++       +        T+         +   +G T    P   N    +A+   + +   +T   L F     I V+E K  +WW GE+             GWFP  +V  V  +N     T+S   YS++     +D              S    EY +ALY YES   GDLT    D++ + +    WW+G I    + G+FPS+YVK
Sbjct:  731 TENNILQPVVIPEVTCS-------SLTTYRALYPFTARNSDELTLEADCFIQVDESTVRET--GWLYGSYSGNR--GWFPESYAERCSKDSQTQPTAAETESTAPSANYPGIPRVDIEGPTPTHTPVSTNTQHSQAVA--LCEWSAKTDSHLGFCKDDIITVLE-KQENWWYGELKEKR---------GWFPCSHVSVVTTNN-----TQSEPLYSSVEEIEVSD--------------SGLLDEY-VALYTYESPESGDLTFSAEDVVLVTEKEGEWWRGCI--GDQTGLFPSNYVK 983          

Query:  524 PKRTSPQTDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGR 787
            PK +S  +DW + Q+ R +YR  FN  D+   G+LSG + +  L  S L+ + LA IW L+D+D DG+L  EEF +AM+LVE A+ GR
Sbjct:  208 PKTSS--SDWAVPQSSRLKYRQLFNSLDKLMSGYLSGPQVRNALTASNLTQTQLATIWFLADVDRDGQLRAEEFILAMHLVEMAKTGR 293          

Query: 1730 LESYQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNVFDQTLPDGATIKKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDM-STHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQTIDTISSD 2596
            L+ Y ALY +   ++ +LTF A D++LV           W  G   I    GLFP+ YVK  +P          D+ +S               A   K P    V  + P        TP+QLS   GQ I V+ + S  WW GE+    +  G     GWF          SN  LL             A S  I  AP                 +A+Y Y++    +++ + G +I +++  +  WWKG + G    G+FP++YVK  T+ D       D +S D
Sbjct:  931 LDEYVALYTYESPESGDLTFSAEDVVLV-----TEKEGEWWRG--CIGDQTGLFPSNYVKPKEP----------DTASS---------------AVPSKKPEIAQVTTVSP------ATTPEQLSLTPGQLIVVLHKNSNSWWLGEL----QARGKKRKKGWF--------QSSNVRLLE------------ANSGKITPAPQPLCQ-----------VIAMYDYKAANKDEMSFQKGQLITVLNKDNPDWWKGEVAGV--TGLFPTNYVKMTTECDPSQQWCADLLSLD 1145          

Query:  551 WVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETL--VPPSMVTISN--NNKSLPN 868
            W I    R ++  QF+       G+LSGD+A+   LQSGL  S+LA IW L+DI  DGK+   EF +AM L++    G+ LPS LP  +   P  ++T S+     S+PN
Sbjct:    8 WAITPEERGKHDKQFDSLAPTL-GYLSGDQARKFFLQSGLPTSVLADIWALADIGKDGKMDRLEFSIAMKLIKLQLQGQPLPSSLPIIMKQTPTPVMTSSSRFGMGSMPN 116          

Query:   83 SQWSISTEEFSQHRIQFEHLNPV-KGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEG 319
            S W++      ++R  F  L+ +  G++SG Q +  LT S L+   L  IW LADVD+DG++   EF +AMHL++    G
Sbjct:  213 SDWAVPQSSRLKYRQLFNSLDKLMSGYLSGPQVRNALTASNLTQTQLATIWFLADVDRDGQLRAEEFILAMHLVEMAKTG 292          

Query: 2822 AKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGST-NEGWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLLVTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLI-MAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIR--RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFF 4957
            A++     A + ++LS  PGQ + ++  +   W+  +L   G    +GW            F   +   L   SG                  +I    QP  ++IAMY Y A N DE+SF K  ++ +++KD P+WW+G      + GLFP NYV+   T C            +PS +              W  D +++ +++ TE E++RQ YI ELI+TE++Y EDL+    VFY+P+ +S  LT  E+  IF+NW +LI  S     AL++RK  +G + P+Q VGDIL S   +   Y+RFCS Q  A ALL++K   S  FK F ++   N RCK MP+SS+ LKPMQRIT+Y L+++NIL+NT   H D  +++ A+  A  LC  VNE +REKENS+RLEWIQ+HV CDG+ E L FNS TN LG RKL++SG L+K KS KEL   LFNDFLLL   S   +  P       S++   Q+KMYK P+ LN VL+ M   PS                  S   +F I      + LK  ++N+R  WV+++ AAS  +IETE   RE +   R  +++G+GRLLVTVLE   LK    P  K++ YCE ++G Q   ++    T NPKW+ + QF IK++  DVLCL+ ++++ F+P+DFLGRTEV +  IK+ +   KGP+ RRL L  V +GE+ V+LDL  +
Sbjct: 1028 AQVTTVSPATTPEQLSLTPGQLIVVLHKNSNSWWLGELQARGKKRKKGW------------FQSSNVRLLEANSG------------------KITPAPQPLCQVIAMYDYKAANKDEMSFQKGQLITVLNKDNPDWWKGE--VAGVTGLFPTNYVKM-TTEC------------DPSQQ--------------WCAD-LLSLDSMCTE-ERKRQGYIHELIQTEESYLEDLELAVEVFYKPMAESGRLTEAEISMIFVNWRELIMCSTKLLKALRVRKKTAGERMPVQVVGDILSSELSHMQAYIRFCSCQLNAAALLQQKTDKSLDFKLFLKKIASNYRCKGMPLSSFLLKPMQRITRYPLLIKNILENTPPAHADHSNLQAALEQAEELCSQVNEAVREKENSDRLEWIQNHVLCDGVIEHLVFNSLTNCLGPRKLLHSGKLHKTKSSKELWALLFNDFLLLTYTSKQFSSSPDKLFNPNSNT---QYKMYKTPVFLNEVLVKMPSDPS------------------SDDPVFHISHIDRVYTLKTDTINERTTWVQKIKAASDHFIETEKLKREKAYQARSQKNSGIGRLLVTVLEATELKPCK-PNGKSNPYCELTMGAQCYTSRHQPDTLNPKWSFNCQFFIKDLYQDVLCLTVFERDQFSPDDFLGRTEVPVATIKKDQ-DGKGPLVRRLLLHEVPTGEVKVRLDLQLY 1659          

Query:   68 MLGNQSQWSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLP 343
            M G  S W+I+ EE  +H  QF+ L P  G++SG QA+++  +S L   +L  IW+LAD+ +DG+M   EFSIAM LIK +L+G  LP+ LP
Sbjct:    1 MNGGFSIWAITPEERGKHDKQFDSLAPTLGYLSGDQARKFFLQSGLPTSVLADIWALADIGKDGKMDRLEFSIAMKLIKLQLQGQPLPSSLP 92          

Query:  524 PKRTSPQTDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGR 787
            PK +S  +DW + Q+ R +YR  FN  D+   G+LSG + +  L  S L+ + LA IW L+D+D DG+L  EEF +AM+LVE A+ GR
Sbjct:  208 PKTSS--SDWAVPQSSRLKYRQLFNSLDKLMSGYLSGPQVRNALTASNLTQTQLATIWFLADVDRDGQLRAEEFILAMHLVEMAKTGR 293          

Query: 1655 TQNNDVKPIFDFHQTNGHKLPDEFDLESYQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNVFDQTLPDGATIKKAP---NNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVK 2539
            T+NN ++P+     T          L +Y+ALY F  R +DELT EA   I V   +   T  GWL G    N+  G FP  Y ++       +        T+         +   +G T    P   N    +A+   + +   +T   L F     I V+E K  +WW GE+             GWFP  +V  V  +N     ++  M   NL     + +    ++       +     Y +ALY YES   GDLT    D++ + +    WW+G I    + G+FPS+YVK
Sbjct:  741 TENNILQPVVIPEVTCS-------SLTTYRALYPFTARNSDELTLEADCFIQVDESTVRET--GWLYGSYSGNR--GWFPESYAERCSKDSQTQPTAAETESTAPSANYPGIPRVDIEGPTPTHTPVSTNTQHSQAVA--LCEWSAKTDSHLGFCKDDIITVLE-KQENWWYGELKEKR---------GWFPCSHVSVVTTNNT---QSDFDMPAGNLLSVLVSLLGLCILAWRRLKCQTLVCLMY-VALYTYESPESGDLTFSAEDVVLVTEKEGEWWRGCI--GDQTGLFPSNYVK 1009          

Query: 1739 YQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNVFDQTLPDGATIKKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDM-STHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQTIDTISSD 2596
            Y ALY +   ++ +LTF A D++LV           W  G   I    GLFP+ YVK  +P          D+ +S               A   K P    V  + P        TP+QLS   GQ I V+ + S  WW GE+    +  G     GWF          SN  LL             A S  I  AP                 +A+Y Y++    +++ + G +I +++  +  WWKG + G    G+FP++YVK  T+ D       D +S D
Sbjct:  960 YVALYTYESPESGDLTFSAEDVVLV-----TEKEGEWWRG--CIGDQTGLFPSNYVKPKEP----------DTASS---------------AVPSKKPEIAQVTTVSP------ATTPEQLSLTPGQLIVVLHKNSNSWWLGEL----QARGKKRKKGWF--------QSSNVRLLE------------ANSGKITPAPQPLCQ-----------VIAMYDYKAANKDEMSFQKGQLITVLNKDNPDWWKGEVAGV--TGLFPTNYVKMTTECDPSQQWCADLLSLD 1171          

Query:  551 WVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETL--VPPSMVTISN--NNKSLPN 868
            W I    R ++  QF+       G+LSGD+A+   LQSGL  S+LA IW L+DI  DGK+   EF +AM L++    G+ LPS LP  +   P  ++T S+     S+PN
Sbjct:    8 WAITPEERGKHDKQFDSLAPTL-GYLSGDQARKFFLQSGLPTSVLADIWALADIGKDGKMDRLEFSIAMKLIKLQLQGQPLPSSLPIIMKQTPTPVMTSSSRFGMGSMPN 116          

Query:   83 SQWSISTEEFSQHRIQFEHLNPV-KGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEG 319
            S W++      ++R  F  L+ +  G++SG Q +  LT S L+   L  IW LADVD+DG++   EF +AMHL++    G
Sbjct:  213 SDWAVPQSSRLKYRQLFNSLDKLMSGYLSGPQVRNALTASNLTQTQLATIWFLADVDRDGQLRAEEFILAMHLVEMAKTG 292          

Query: 1739 YQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFF-----------GLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNVFDQTLPDGATIKKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQTIDTISSDYYTALSLENSNSPTM-------------TYDDIGRNLNDFDTDSGIT----DPELATPAEIGENAAY--SNYCTLAXXXXXXXXXXXXXXXLSK----AKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNE-GWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLL--VTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLI-MAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIR--RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFF 4957
            Y+ALY F  R  DE+T + GDII+V + S    P GWL G LK    +           G FP+   +  D      + L P + T             P   T   A +N W +    W  +  D+                E  + D W                 G  P + V       +    T +T+  S     + + + G               G    ALYP+ +     L     DII +++    WW G ++G  + G FP  YVK L    L  + +ID+ SS+  +  SL+  +SP               TY+   +    F     I     D +  T   +GE      SNY  +         +     SL K    A+++ +Y+A   ++L+  PGQ + I   +   W++ +L   G   + GW P   +     + +   TN                SLP             P  ++I MY Y AQN DEL+F K  ++ +++K++P+WW+G       +GLFP NYV+      + D         +PS +              W  D  ++   +L+  E++RQ YI ELI TE+ Y  DLQ V   F +P+ +S LLT +E+  IF+NW +LI  +     AL++RK  SG K P++ +GDIL +  P+   Y+RFCS Q    AL+++K     +FKEF ++   + RCK MP+SS+ LKPMQR+T+Y LI++NI++NT + HPD   +++A+  A  LC  VNEG+REKENS+RLEWIQ HVQC+GL+E+L FNS TN LG RK ++SG LYKAKS KEL GFLFNDFLLL  +     ++G   VF    S    +Q+KMYK PI LN VL+ +   PS                      IF I      + L+A S+N+R  WV+++ AAS  YIETE   RE +  +R  R+ G+GRL+V ++EG  LK   T   K++ YCE ++G+Q   TK +  T NPKWN + QF IK++E DVLC++ ++++ F+P+DFLGRTE+ + DIK+ +  +KGP+ + L L  V +GE++V+LDL  F
Sbjct:  742 YRALYPFDARSHDEITIQPGDIIMV-DESQTGEP-GWLGGELKGKTGWFPANYAERMPEGEFPSTTKQAADTTAKPTVHLAPSTPT-------------PAAFTDNSANSNNWADFSSTWPTNNTDKA---------------ETDNWDTW-----------------GAQPSLTVPSAGQHRQRSAFTPATVTGS-----SPSPVLG---------QGEKVEGLQAQALYPWRAKKDNHLNFNKNDIITVLEQQDMWWFGEVQG--QKGWFPKSYVK-LISGPLRKSTSIDSTSSE--SPASLKRVSSPAFKPAMQGEEYIAMYTYESNEQGDLTFQQGDLIVVIKKDGDWWT-GTVGEKTGVFPSNY--VRPKDSEAAGSAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYV-----KLLSPGTNKSTPTEPPKAT-----SLP-------------PTCQVIGMYDYIAQNDDELAFGKGQVINVLNKEDPDWWKGE--LNGHVGLFPSNYVK-----LTTD--------MDPSQQ--------------WCAD--LHLLDMLSPTERKRQGYIHELIVTEENYVNDLQLVTETFQKPLLESELLTEKEVAMIFVNWKELIMCNIKLLKALRVRKKMSGEKMPVKMIGDILTAQLPHMQPYIRFCSCQLNGAALIQQKTDEVPEFKEFVKRLAMDPRCKGMPLSSFLLKPMQRVTRYPLIIKNIIENTPENHPDHSHLKQALEKAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQIIKPLGSSGNDKVF----SPKSNLQYKMYKTPIFLNEVLVKLPTDPS------------------GDEPIFHISHIDRVYTLRAESINERTAWVQKIKAASELYIETEKKKREKAYLVRSQRATGIGRLMVNIVEGIELKPCRT-HGKSNPYCEITMGSQCHITKTIQDTLNPKWNSNCQFFIKDLEQDVLCITVFERDQFSPDDFLGRTEIRVADIKKDQ-GSKGPVTKCLLLHEVPTGEIVVRLDLQLF 1707          

Query:   71 LGNQSQWSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPP------------DSFPFSDLGANEIFSSKAA---PSYNEVMAKDKADRQSFREKPPIPQDIQSTFPPLP---------KRTS--------------------------PQTDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSMVTISNNN 853
             GN   W+I+ EE ++H  QF  L P  G+I+G QA+ +  +S L   +L +IW+LAD++ DGRM   EFSIAM LIK KL+G  LP+ LP  ML  P              F  S +      ++ A    PS   V+        S    PP+     +   PLP         K +S                          P  +W + Q+ R +YR  FN  D+   G L+G +A+ +L+QS L  S LA IWNLSDID DGKLT EEF +AM+L++ A +G+ LP  LP   +PPS   + + +
Sbjct:   10 FGNLDIWAITVEERAKHDQQFHGLQPTAGYITGDQARNFFLQSGLPQPVLAQIWALADMNNDGRMDQLEFSIAMKLIKLKLQGYPLPSALPSNMLKQPVAMSAAAAAAAAAGFGMSGISGIPPLAAVAPVPMPSI-PVVGMSPPLVSSVPTVPPLANGAPAVIQPLPAFAHSATLPKSSSFGRSGAGSQMNTKLQKAQSFDVPTPPPLAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQSQLATIWNLSDIDLDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGS 319          

Query: 2381 YCLALYPYESTVPGDLTMRPGDIIQIVDMSTH---WWKGHIRGARENGMFPSHYVKKLTKQDLEHA--QTIDT-------ISSDYYTALSLENSNSPTMTYDDIGRNLNDFDTDSGITD--------PELATPAEIGENAAYSNY--CTLAXXXXXXXXXXXXXXXLSKAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNEGWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVR 3289
            Y  ALYP+++    ++T++PGDII + +  T    W  G ++G  + G FP++Y +++ + +      Q  DT       ++    T  +  ++++ +  + D        +TD   TD        P L  P+  G++   S +   T+  SS         +    +A+ +  + A   + L+      + +++  D+ W+     + G   +GW P+  + K  +  +R  T+   T+S     L  + S       Q        G++ IAMY Y +    +L+F +  ++ +I KD  +WW G        G+FP NYVR
Sbjct:  741 YYRALYPFDARSHDEITIQPGDIIMVDESQTGEPGWLGGELKG--KTGWFPANYAERMPEGEFPSTTKQAADTTAKPTVHLAPSTPTPAAFTDNSANSNNWADFSSTWPTNNTDKAETDNWDTWGAQPSLTVPS-AGQHRQRSAFTPATVTGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDIITVLEQQDMWWFG---EVQG--QKGWFPKSYV-KLISGPLRKSTSIDSTSSESPASLKRVSSPAFKPAMQ--------GEEYIAMYTYESNEQGDLTFQQGDLIVVIKKDG-DWWTG--TVGEKTGVFPSNYVR 1045          

Query: 1733 ESYQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNVFDQTLPDGATIKKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQ 2236
            E  Q +  +     ++LT   G +IL+R  +P     G L  R K  Q  G FP  YVK          +L+P +  ST  E        P  AT    P    V  ++ +I   +DE    L+F  GQ I V+ ++  DWWKGE+  H         VG FP  YV+
Sbjct: 1066 EIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQI-GWFPANYVK----------LLSPGTNKSTPTE--------PPKAT--SLPPTCQVIGMYDYIAQNDDE----LAFGKGQVINVLNKEDPDWWKGELNGH---------VGLFPSNYVK 1199          

Query: 1739 YQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFF-----------GLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNVFDQTLPDGATIKKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQTIDTISSDYYTALSLENSNSPTM-------------TYDDIGRNLNDFDTDSGIT----DPELATPAEIGENAAY--SNYCTLAXXXXXXXXXXXXXXXLSK----AKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNE-GWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLL--VTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLI-MAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIR--RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFF 4957
            Y+ALY F  R  DE+T + GDII+V + S    P GWL G LK    +           G FP+   +  D      + L P + T             P   T   A +N W +    W  +  D+                E  + D W                 G  P + V       +    T +T+  S     + + + G               G    ALYP+ +     L     DII +++    WW G ++G  + G FP  YVK L    L  + +ID+ SS+  +  SL+  +SP               TY+   +    F     I     D +  T   +GE      SNY  +         +     SL K    A+++ +Y+A   ++L+  PGQ + I   +   W++ +L   G   + GW P   +     + +   TN                SLP             P  ++I MY Y AQN DEL+F K  ++ +++K++P+WW+G       +GLFP NYV+      + D         +PS +              W  D  ++   +L+  E++RQ YI ELI TE+ Y  DLQ V   F +P+ +S LLT +E+  IF+NW +LI  +     AL++RK  SG K P++ +GDIL +  P+   Y+RFCS Q    AL+++K     +FKEF ++   + RCK MP+SS+ LKPMQR+T+Y LI++NI++NT + HPD   +++A+  A  LC  VNEG+REKENS+RLEWIQ HVQC+GL+E+L FNS TN LG RK ++SG LYKAKS KEL GFLFNDFLLL  +     ++G   VF    S    +Q+KMYK PI LN VL+ +   PS                      IF I      + L+A S+N+R  WV+++ AAS  YIETE   RE +  +R  R+ G+GRL+V ++EG  LK   T   K++ YCE ++G+Q   TK +  T NPKWN + QF IK++E DVLC++ ++++ F+P+DFLGRTE+ + DIK+ +  +KGP+ + L L  V +GE++V+LDL  F
Sbjct:  736 YRALYPFDARSHDEITIQPGDIIMV-DESQTGEP-GWLGGELKGKTGWFPANYAERMPEGEFPSTTKQAADTTAKPTVHLAPSTPT-------------PAAFTDNSANSNNWADFSSTWPTNNTDKA---------------ETDNWDTW-----------------GAQPSLTVPSAGQHRQRSAFTPATVTGS-----SPSPVLG---------QGEKVEGLQAQALYPWRAKKDNHLNFNKNDIITVLEQQDMWWFGEVQG--QKGWFPKSYVK-LISGPLRKSTSIDSTSSE--SPASLKRVSSPAFKPAMQGEEYIAMYTYESNEQGDLTFQQGDLIVVIKKDGDWWT-GTVGEKTGVFPSNY--VRPKDSEAAGSAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYV-----KLLSPGTNKSTPTEPPKAT-----SLP-------------PTCQVIGMYDYIAQNDDELAFGKGQVINVLNKEDPDWWKGE--LNGHVGLFPSNYVK-----LTTD--------MDPSQQ--------------WCAD--LHLLDMLSPTERKRQGYIHELIVTEENYVNDLQLVTETFQKPLLESELLTEKEVAMIFVNWKELIMCNIKLLKALRVRKKMSGEKMPVKMIGDILTAQLPHMQPYIRFCSCQLNGAALIQQKTDEVPEFKEFVKRLAMDPRCKGMPLSSFLLKPMQRVTRYPLIIKNIIENTPENHPDHSHLKQALEKAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQIIKPLGSSGNDKVF----SPKSNLQYKMYKTPIFLNEVLVKLPTDPS------------------GDEPIFHISHIDRVYTLRAESINERTAWVQKIKAASELYIETEKKKREKAYLVRSQRATGIGRLMVNIVEGIELKPCRT-HGKSNPYCEITMGSQCHITKTIQDTLNPKWNSNCQFFIKDLEQDVLCITVFERDQFSPDDFLGRTEIRVADIKKDQ-GSKGPVTKCLLLHEVPTGEIVVRLDLQLF 1701          

Query:   71 LGNQSQWSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPPDSFPFSDLGANEIFSSKAAPSYNEVMAKDKADRQSFREKPPIPQDIQSTFPPL--------------------PKRTS--------------------------PQTDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSMVTISNNN 853
            +GN   W+I+ EE ++H  QF  L P  G+I+G QA+ +  +S L   +L +IW+LAD++ DGRM   EFSIAM LIK KL+G  LP+ LP  ML  P +   +   A         P    V              PP+   +  T PPL                    PK +S                          P  +W + Q+ R +YR  FN  D+   G L+G +A+ +L+QS L  S LA IWNLSDID DGKLT EEF +AM+L++ A +G+ LP  LP   +PPS   + + +
Sbjct:    7 IGNLDIWAITVEERAKHDQQFHGLQPTAGYITGDQARNFFLQSGLPQPVLAQIWALADMNNDGRMDQLEFSIAMKLIKLKLQGYPLPSALPSNMLKQPVAMSAAAAAAAAAGGISGIPPLAAVAPVPMPSIPVVGMSPPLVSSV-PTVPPLANGAPAVIQPLPAFAHSATLPKSSSFGRSGAGSQMNTKLQKAQSFDVPTPPPLAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQSQLATIWNLSDIDLDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGS 312          

Query: 2381 YCLALYPYESTVPGDLTMRPGDIIQIVDMSTH---WWKGHIRGARENGMFPSHYVKKLTKQDLEHA--QTIDT-------ISSDYYTALSLENSNSPTMTYDDIGRNLNDFDTDSGITD--------PELATPAEIGENAAYSNY--CTLAXXXXXXXXXXXXXXXLSKAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNEGWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVR 3289
            Y  ALYP+++    ++T++PGDII + +  T    W  G ++G  + G FP++Y +++ + +      Q  DT       ++    T  +  ++++ +  + D        +TD   TD        P L  P+  G++   S +   T+  SS         +    +A+ +  + A   + L+      + +++  D+ W+     + G   +GW P+  + K  +  +R  T+   T+S     L  + S       Q        G++ IAMY Y +    +L+F +  ++ +I KD  +WW G        G+FP NYVR
Sbjct:  735 YYRALYPFDARSHDEITIQPGDIIMVDESQTGEPGWLGGELKG--KTGWFPANYAERMPEGEFPSTTKQAADTTAKPTVHLAPSTPTPAAFTDNSANSNNWADFSSTWPTNNTDKAETDNWDTWGAQPSLTVPS-AGQHRQRSAFTPATVTGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDIITVLEQQDMWWFG---EVQG--QKGWFPKSYV-KLISGPLRKSTSIDSTSSESPASLKRVSSPAFKPAMQ--------GEEYIAMYTYESNEQGDLTFQQGDLIVVIKKDG-DWWTG--TVGEKTGVFPSNYVR 1039          

Query: 1733 ESYQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNVFDQTLPDGATIKKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQ 2236
            E  Q +  +     ++LT   G +IL+R  +P     G L  R K  Q  G FP  YVK          +L+P +  ST  E        P  AT    P    V  ++ +I   +DE    L+F  GQ I V+ ++  DWWKGE+  H         VG FP  YV+
Sbjct: 1060 EIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQI-GWFPANYVK----------LLSPGTNKSTPTE--------PPKAT--SLPPTCQVIGMYDYIAQNDDE----LAFGKGQVINVLNKEDPDWWKGELNGH---------VGLFPSNYVK 1193          

Query: 1739 YQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFF-----------GLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNVFDQTLPDGATIKKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQTIDTISSDYYTALSLENSNSPTM-------------TYDDIGRNLNDFDTDSGIT----DPELATPAEIGENAAY--SNYCTLAXXXXXXXXXXXXXXXLSK----AKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNE-GWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLL--VTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLI-MAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIR--RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFF 4957
            Y+ALY F  R  DE+T + GDII+V + S    P GWL G LK    +           G FP+   +  D      + L P + T             P   T   A +N W +    W  +  D+                E  + D W                 G  P + V       +    T +T+  S     + + + G               G    ALYP+ +     L     DII +++    WW G ++G +  G FP  YVK L    L  + +ID+ SS+  +  SL+  +SP               TY+   +    F     I     D +  T   +GE      SNY  +         +     SL K    A+++ +Y+A   ++L+  PGQ + I   +   W++ +L   G   + GW P   +     + +   TN                SLP             P  ++I MY Y AQN DEL+F K  ++ +++K++P+WW+G       +GLFP NYV+      + D         +PS +              W  D  ++   +L+  E++RQ YI ELI TE+ Y  DLQ V   F +P+ +S LLT +E+  IF+NW +LI  +     AL++RK  SG K P++ +GDIL +  P+   Y+RFCS Q    AL+++K     +FKEF ++   + RCK MP+SS+ LKPMQR+T+Y LI++NI++NT + HPD   +++A+  A  LC  VNEG+REKENS+RLEWIQ HVQC+GL+E+L FNS TN LG RK ++SG LYKAKS KEL GFLFNDFLLL  +     ++G   VF    S    +Q+KMYK PI LN VL+ +   PS                      IF I      + L+A S+N+R  WV+++ AAS  YIETE   RE +  +R  R+ G+GRL+V ++EG  LK   T   K++ YCE ++G+Q   TK +  T NPKWN + QF IK++E DVLC++ ++++ F+P+DFLGRTE+ + DIK+ +  +KGP+ + L L  V +GE++V+LDL  F
Sbjct:  682 YRALYPFDARSHDEITIQPGDIIMV-DESQTGEP-GWLGGELKGKTGWFPANYAERMPEGEFPSTTKQAADTTAKPTVHLAPSTPT-------------PAAFTDNSANSNNWADFSSTWPTNNTDKA---------------ETDNWDTW-----------------GAQPSLTVPSAGQHRQRSAFTPATVTGS-----SPSPVLG---------QGEKVEGLQAQALYPWRAKKDNHLNFNKNDIITVLEQQDMWWFGEVQGQK--GWFPKSYVK-LISGPLRKSTSIDSTSSE--SPASLKRVSSPAFKPAMQGEEYIAMYTYESNEQGDLTFQQGDLIVVIKKDGDWWT-GTVGEKTGVFPSNY--VRPKDSEAAGSAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYV-----KLLSPGTNKSTPTEP-----PKATSLP-------------PTCQVIGMYDYIAQNDDELAFGKGQVINVLNKEDPDWWKGE--LNGHVGLFPSNYVK-----LTTD--------MDPSQQ--------------WCAD--LHLLDMLSPTERKRQGYIHELIVTEENYVNDLQLVTETFQKPLLESELLTEKEVAMIFVNWKELIMCNIKLLKALRVRKKMSGEKMPVKMIGDILTAQLPHMQPYIRFCSCQLNGAALIQQKTDEVPEFKEFVKRLAMDPRCKGMPLSSFLLKPMQRVTRYPLIIKNIIENTPENHPDHSHLKQALEKAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQIIKPLGSSGNDKVF----SPKSNLQYKMYKTPIFLNEVLVKLPTDPS------------------GDEPIFHISHIDRVYTLRAESINERTAWVQKIKAASELYIETEKKKREKAYLVRSQRATGIGRLMVNIVEGIELKPCRT-HGKSNPYCEITMGSQCHITKTIQDTLNPKWNSNCQFFIKDLEQDVLCITVFERDQFSPDDFLGRTEIRVADIKKDQ-GSKGPVTKCLLLHEVPTGEIVVRLDLQLF 1647          

Query:   74 GNQSQWSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPPDSFP----------FSDLGANEIFSSKAAPSYNEVMAKDKADRQSFREKPPIPQDIQSTFPPLPKRTSPQTDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSMVTISNNNKSLPNS 871
            GN   W+I+ EE ++H  QF  L P  G+I+G QA+ +  +S L   +L +IW+LAD++ DGRM   EFSIAM LIK KL+G  LP+ LP  ML  P +            F+ L  +  F    A S    M       QSF        D+  T PPL        +W + Q+ R +YR  FN  D+   G L+G +A+ +L+QS L  S LA IWNLSDID DGKLT EEF +AM+L++ A +G+ LP  LP   +PPS    S +  S+ +S
Sbjct:   10 GNLDIWAITVEERAKHDQQFHGLQPTAGYITGDQARNFFLQSGLPQPVLAQIWALADMNNDGRMDQLEFSIAMKLIKLKLQGYPLPSALPSNMLKQPVAMSAAAAAAAAAGFATLPKSSSFGRSGAGSQ---MNTKLQKAQSF--------DV-PTPPPL-------AEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQSQLATIWNLSDIDLDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRVRSGSGLSIMSS 266          

Query: 2381 YCLALYPYESTVPGDLTMRPGDIIQIVDMSTH---WWKGHIRGARENGMFPSHYVKKLTKQDLEHA--QTIDT-------ISSDYYTALSLENSNSPTMTYDDIGRNLNDFDTDSGITD--------PELATPAEIGENAAYSNY--CTLAXXXXXXXXXXXXXXXLSKAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNEGWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVR 3289
            Y  ALYP+++    ++T++PGDII + +  T    W  G ++G  + G FP++Y +++ + +      Q  DT       ++    T  +  ++++ +  + D        +TD   TD        P L  P+  G++   S +   T+  SS         +    +A+ +  + A   + L+      + +++  D+ W+     + G   +GW P+  + K  +  +R  T+   T+S     L  + S       Q        G++ IAMY Y +    +L+F +  ++ +I KD  +WW G        G+FP NYVR
Sbjct:  681 YYRALYPFDARSHDEITIQPGDIIMVDESQTGEPGWLGGELKG--KTGWFPANYAERMPEGEFPSTTKQAADTTAKPTVHLAPSTPTPAAFTDNSANSNNWADFSSTWPTNNTDKAETDNWDTWGAQPSLTVPS-AGQHRQRSAFTPATVTGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDIITVLEQQDMWWFG---EVQG--QKGWFPKSYV-KLISGPLRKSTSIDSTSSESPASLKRVSSPAFKPAMQ--------GEEYIAMYTYESNEQGDLTFQQGDLIVVIKKDG-DWWTG--TVGEKTGVFPSNYVR 985          

Query: 1733 ESYQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNVFDQTLPDGATIKKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQ 2236
            E  Q +  +     ++LT   G +IL+R  +P     G L  R K  Q  G FP  YVK          +L+P +  ST  E        P  AT    P    V  ++ +I   +DE    L+F  GQ I V+ ++  DWWKGE+  H         VG FP  YV+
Sbjct: 1006 EIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQI-GWFPANYVK----------LLSPGTNKSTPTE--------PPKAT--SLPPTCQVIGMYDYIAQNDDE----LAFGKGQVINVLNKEDPDWWKGELNGH---------VGLFPSNYVK 1139          

Query: 1739 YQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFF-----------GLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNVFDQTLPDGATIKKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQTIDTISSDYYTALSLENSNSPTM-------------TYDDIGRNLNDFDTDSGIT----DPELATPAEIGENAAY--SNYCTLAXXXXXXXXXXXXXXXLSK----AKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNE-GWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLL--VTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLI-MAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIR--RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFF 4957
            Y+ALY F  R  DE+T + GDII+V + S    P GWL G LK    +           G FP+   +  D      + L P + T             P   T   A +N W +    W  +  D+                E  + D W                 G  P + V       +    T +T+  S     + + + G               G    ALYP+ +     L     DII +++    WW G ++G  + G FP  YVK L    L  + +ID+ SS+  +  SL+  +SP               TY+   +    F     I     D +  T   +GE      SNY  +         +     SL K    A+++ +Y+A   ++L+  PGQ + I   +   W++ +L   G   + GW P   +     + +   TN                SLP             P  ++I MY Y AQN DEL+F K  ++ +++K++P+WW+G       +GLFP NYV+      + D         +PS +              W  D  ++   +L+  E++RQ YI ELI TE+ Y  DLQ V   F +P+ +S LLT +E+  IF+NW +LI  +     AL++RK  SG K P++ +GDIL +  P+   Y+RFCS Q    AL+++K     +FKEF ++   + RCK MP+SS+ LKPMQR+T+Y LI++NI++NT + HPD   +++A+  A  LC  VNEG+REKENS+RLEWIQ HVQC+GL+E+L FNS TN LG RK ++SG LYKAKS KEL GFLFNDFLLL  +     ++G   VF    S    +Q+KMYK PI LN VL+ +   PS                      IF I      + L+A S+N+R  WV+++ AAS  YIETE   RE +  +R  R+ G+GRL+V ++EG  LK   T   K++ YCE ++G+Q   TK +  T NPKWN + QF IK++E DVLC++ ++++ F+P+DFLGRTE+ + DIK+ +  +KGP+ + L L  V +GE++V+LDL  F
Sbjct:  722 YRALYPFDARSHDEITIQPGDIIMV-DESQTGEP-GWLGGELKGKTGWFPANYAERMPEGEFPSTTKQAADTTAKPTVHLAPSTPT-------------PAAFTDNSANSNNWADFSSTWPTNNTDKA---------------ETDNWDTW-----------------GAQPSLTVPSAGQHRQRSAFTPATVTGS-----SPSPVLG---------QGEKVEGLQAQALYPWRAKKDNHLNFNKNDIITVLEQQDMWWFGEVQG--QKGWFPKSYVK-LISGPLRKSTSIDSTSSE--SPASLKRVSSPAFKPAMQGEEYIAMYTYESNEQGDLTFQQGDLIVVIKKDGDWWT-GTVGEKTGVFPSNY--VRPKDSEAAGSAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYV-----KLLSPGTNKSTPTEPPKAT-----SLP-------------PTCQVIGMYDYIAQNDDELAFGKGQVINVLNKEDPDWWKGE--LNGHVGLFPSNYVK-----LTTD--------MDPSQQ--------------WCAD--LHLLDMLSPTERKRQGYIHELIVTEENYVNDLQLVTETFQKPLLESELLTEKEVAMIFVNWKELIMCNIKLLKALRVRKKMSGEKMPVKMIGDILTAQLPHMQPYIRFCSCQLNGAALIQQKTDEVPEFKEFVKRLAMDPRCKGMPLSSFLLKPMQRVTRYPLIIKNIIENTPENHPDHSHLKQALEKAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQIIKPLGSSGNDKVF----SPKSNLQYKMYKTPIFLNEVLVKLPTDPS------------------GDEPIFHISHIDRVYTLRAESINERTAWVQKIKAASELYIETEKKKREKAYLVRSQRATGIGRLMVNIVEGIELKPCRT-HGKSNPYCEITMGSQCHITKTIQDTLNPKWNSNCQFFIKDLEQDVLCITVFERDQFSPDDFLGRTEIRVADIKKDQ-GSKGPVTKCLLLHEVPTGEIVVRLDLQLF 1687          

Query:   89 WSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPPDSFPFSDLGANEIFSSKAA-----PSYNEVMAKDKADRQSFREKPPIPQDIQSTFPPLP---------KRTS--------------------------PQTDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSMVTISNNN 853
            W  +  E ++H  QF  L P  G+I+G QA+ +  +S L   +L +IW+LAD++ DGRM   EFSIAM LIK KL+G  LP+ LP  ML  P +  +  +G + I    A      PS   V+        S    PP+     +   PLP         K +S                          P  +W + Q+ R +YR  FN  D+   G L+G +A+ +L+QS L  S LA IWNLSDID DGKLT EEF +AM+L++ A +G+ LP  LP   +PPS   + + +
Sbjct:    7 WVQTHWERAKHDQQFHGLQPTAGYITGDQARNFFLQSGLPQPVLAQIWALADMNNDGRMDQLEFSIAMKLIKLKLQGYPLPSALPSNMLKQPVAIGYG-VGIHGIPPLAAVAPVPMPSI-PVVGMSPPLVSSVPTVPPLANGAPAVIQPLPAFAHSATLPKSSSFGRSGAGSQMNTKLQKAQSFDVPTPPPLAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQSQLATIWNLSDIDLDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGS 299          

Query: 2381 YCLALYPYESTVPGDLTMRPGDIIQIVDMSTH---WWKGHIRGARENGMFPSHYVKKLTKQDLEHA--QTIDT-------ISSDYYTALSLENSNSPTMTYDDIGRNLNDFDTDSGITD--------PELATPAEIGENAAYSNY--CTLAXXXXXXXXXXXXXXXLSKAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNEGWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVR 3289
            Y  ALYP+++    ++T++PGDII + +  T    W  G ++G  + G FP++Y +++ + +      Q  DT       ++    T  +  ++++ +  + D        +TD   TD        P L  P+  G++   S +   T+  SS         +    +A+ +  + A   + L+      + +++  D+ W+     + G   +GW P+  + K  +  +R  T+   T+S     L  + S       Q        G++ IAMY Y +    +L+F +  ++ +I KD  +WW G        G+FP NYVR
Sbjct:  721 YYRALYPFDARSHDEITIQPGDIIMVDESQTGEPGWLGGELKG--KTGWFPANYAERMPEGEFPSTTKQAADTTAKPTVHLAPSTPTPAAFTDNSANSNNWADFSSTWPTNNTDKAETDNWDTWGAQPSLTVPS-AGQHRQRSAFTPATVTGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDIITVLEQQDMWWFG---EVQG--QKGWFPKSYV-KLISGPLRKSTSIDSTSSESPASLKRVSSPAFKPAMQ--------GEEYIAMYTYESNEQGDLTFQQGDLIVVIKKDG-DWWTG--TVGEKTGVFPSNYVR 1025          

Query:   83 SQWSISTEEFSQHRIQF-EHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVP 361
            ++W++      ++R  F  H   + G ++G QA+  L +S L    L  IW+L+D+D DG+++  EF +AMHLI   + G  LP VLP E + P
Sbjct:  197 AEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQSQLATIWNLSDIDLDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPP 290          

Query: 1733 ESYQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNVFDQTLPDGATIKKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQ 2236
            E  Q +  +     ++LT   G +IL+R  +P     G L  R K  Q  G FP  YVK          +L+P +  ST  E        P  AT    P    V  ++ +I   +DE    L+F  GQ I V+ ++  DWWKGE+  H         VG FP  YV+
Sbjct: 1046 EIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQI-GWFPANYVK----------LLSPGTNKSTPTE--------PPKAT--SLPPTCQVIGMYDYIAQNDDE----LAFGKGQVINVLNKEDPDWWKGELNGH---------VGLFPSNYVK 1179          

Query: 1739 YQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFF-----------GLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNVFDQTLPDGATIKKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQTIDTISSDYYTALSLENSNSPTM-------------TYDDIGRNLNDFDTDSGIT----DPELATPAEIGENAAY--SNYCTLAXXXXXXXXXXXXXXXLSK----AKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNE-GWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRID----DGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLL--VTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLI-MAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIR--RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFF 4957
            Y+ALY F  R  DE+T + GDII+V + S    P GWL G LK    +           G FP+   +  D      + L P + T             P   T   A +N W +    W  +  D+                E  + D W                 G  P + V       +    T +T+  S     + + + G               G    ALYP+ +     L     DII +++    WW G ++G  + G FP  YVK L    L  + +ID+ SS+  +  SL+  +SP               TY+   +    F     I     D +  T   +GE      SNY  +         +     SL K    A+++ +Y+A   ++L+  PGQ + I   +   W++ +L   G   + GW P                      + Y + L+     P + +S   +      + P  ++I MY Y AQN DEL+F K  ++ +++K++P+WW+G       +GLFP NYV+      + D         +PS +              W  D  ++   +L+  E++RQ YI ELI TE+ Y  DLQ V   F +P+ +S LLT +E+  IF+NW +LI  +     AL++RK  SG K P++ +GDIL +  P+   Y+RFCS Q    AL+++K     +FKEF ++   + RCK MP+SS+ LKPMQR+T+Y LI++NI++NT + HPD   +++A+  A  LC  VNEG+REKENS+RLEWIQ HVQC+GL+E+L FNS TN LG RK ++SG LYKAKS KEL GFLFNDFLLL  +     ++G   VF    S    +Q+KMYK PI LN VL+ +   PS                      IF I      + L+A S+N+R  WV+++ AAS  YIETE   RE +  +R  R+ G+GRL+V ++EG  LK   T   K++ YCE ++G+Q   TK +  T NPKWN + QF IK++E DVLC++ ++++ F+P+DFLGRTE+ + DIK+ +  +KGP+ + L L  V +GE++V+LDL  F
Sbjct:  673 YRALYPFDARSHDEITIQPGDIIMV-DESQTGEP-GWLGGELKGKTGWFPANYAERMPEGEFPSTTKQAADTTAKPTVHLAPSTPT-------------PAAFTDNSANSNNWADFSSTWPTNNTDKA---------------ETDNWDTW-----------------GAQPSLTVPSAGQHRQRSAFTPATVTGS-----SPSPVLG---------QGEKVEGLQAQALYPWRAKKDNHLNFNKNDIITVLEQQDMWWFGEVQG--QKGWFPKSYVK-LISGPLRKSTSIDSTSSE--SPASLKRVSSPAFKPAMQGEEYIAMYTYESNEQGDLTFQQGDLIVVIKKDGDWWT-GTVGEKTGVFPSNY--VRPKDSEAAGSAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFP----------------------ANYVKLLS-----PGTNKSTPTEPPKATSLPPTCQVIGMYDYIAQNDDELAFGKGQVINVLNKEDPDWWKGE--LNGHVGLFPSNYVK-----LTTD--------MDPSQQ--------------WCAD--LHLLDMLSPTERKRQGYIHELIVTEENYVNDLQLVTETFQKPLLESELLTEKEVAMIFVNWKELIMCNIKLLKALRVRKKMSGEKMPVKMIGDILTAQLPHMQPYIRFCSCQLNGAALIQQKTDEVPEFKEFVKRLAMDPRCKGMPLSSFLLKPMQRVTRYPLIIKNIIENTPENHPDHSHLKQALEKAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQIIKPLGSSGNDKVF----SPKSNLQYKMYKTPIFLNEVLVKLPTDPSGD------------------EPIFHISHIDRVYTLRAESINERTAWVQKIKAASELYIETEKKKREKAYLVRSQRATGIGRLMVNIVEGIELKPCRT-HGKSNPYCEITMGSQCHITKTIQDTLNPKWNSNCQFFIKDLEQDVLCITVFERDQFSPDDFLGRTEIRVADIKKDQ-GSKGPVTKCLLLHEVPTGEIVVRLDLQLF 1638          

Query:   71 LGNQSQWSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEG--IELPNVLPKEML--VPPDSFPFSDLGANEIFS-------SKAAPSYNE---VMAKDKADRQSFREKPPIPQDIQSTFPPLPKRTSPQTDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSMVTISNNN 853
            +GN   W+I+ EE ++H  QF  L P  G+I+G QA+ +  +S L   +L +IW+LAD++ DGRM   EFSIAM LIK KL+G  + +  + P   +  VP  S P   +    + S       +  AP+  +     A   A  Q   +     Q  QS   P P    P  +W + Q+ R +YR  FN  D+   G L+G +A+ +L+QS L  S LA IWNLSDID DGKLT EEF +AM+L++ A +G+ LP  LP   +PPS   + + +
Sbjct:    7 IGNLDIWAITVEERAKHDQQFHGLQPTAGYITGDQARNFFLQSGLPQPVLAQIWALADMNNDGRMDQLEFSIAMKLIKLKLQGYPLGISGIPPLAAVAPVPMPSIPVVGMSPPLVSSVPTVPPLANGAPAVIQPLPAFAHSGAGSQMNTKL----QKAQSFDVPTP---PPLAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQSQLATIWNLSDIDLDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGS 274          

Query: 2381 YCLALYPYESTVPGDLTMRPGDIIQIVDMSTH---WWKGHIRGARENGMFPSHYVKKLTKQDLEHA--QTIDT-------ISSDYYTALSLENSNSPTMTYDDIGRNLNDFDTDSGITD--------PELATPAEIGENAAYSNY--CTLAXXXXXXXXXXXXXXXLSKAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNEGWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVR 3289
            Y  ALYP+++    ++T++PGDII + +  T    W  G ++G  + G FP++Y +++ + +      Q  DT       ++    T  +  ++++ +  + D        +TD   TD        P L  P+  G++   S +   T+  SS         +    +A+ +  + A   + L+      + +++  D+ W+     + G   +GW P+  + K  +  +R  T+   T+S     L  + S       Q        G++ IAMY Y +    +L+F +  ++ +I KD  +WW G        G+FP NYVR
Sbjct:  672 YYRALYPFDARSHDEITIQPGDIIMVDESQTGEPGWLGGELKG--KTGWFPANYAERMPEGEFPSTTKQAADTTAKPTVHLAPSTPTPAAFTDNSANSNNWADFSSTWPTNNTDKAETDNWDTWGAQPSLTVPS-AGQHRQRSAFTPATVTGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDIITVLEQQDMWWFG---EVQG--QKGWFPKSYV-KLISGPLRKSTSIDSTSSESPASLKRVSSPAFKPAMQ--------GEEYIAMYTYESNEQGDLTFQQGDLIVVIKKDG-DWWTG--TVGEKTGVFPSNYVR 976          

Query: 1733 ESYQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNVFDQTLPDGATIKKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQ 2236
            E  Q +  +     ++LT   G +IL+R  +P     G L  R K  Q  G FP  YVK          +L+P +  ST  E        P  AT    P    V  ++ +I   +DE    L+F  GQ I V+ ++  DWWKGE+  H         VG FP  YV+
Sbjct:  997 EIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQI-GWFPANYVK----------LLSPGTNKSTPTE--------PPKAT--SLPPTCQVIGMYDYIAQNDDE----LAFGKGQVINVLNKEDPDWWKGELNGH---------VGLFPSNYVK 1130          

Query: 2375 GEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQTIDTISSDYYTALSLENSNSPTM-------------TYDDIGRNLNDFDTDSGIT----DPELATPAEIGENAAY--SNYCTLAXXXXXXXXXXXXXXXLSK----AKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNE-GWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGD-KLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLL--VTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLI-MAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIR--RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFF 4957
            G    ALYP+ +     L     D+I +++    WW G ++G  + G FP  YVK L    +  + +IDT  ++  +  SL+   SP               TY+   +    F     I     D +  T   +G+ +    SNY  L               SL K    A+++ +Y+A   ++L+  PGQ + I   +   W++ +L   G   + GW P   +               + + G  +       LP +         +QP   ++I MY Y+AQN DEL+F+K  I+ +++K++P+WW+G    +  +GLFP NYV+      + D         +PS +              W  D  ++   +LT  E++RQ YI ELI TE+ Y  DLQ V  +F +P+ +S LLT +E+  IF+NW +LI  +     AL++RK  SG K P++ +GDIL +  P+   Y+RFCS Q    AL+++K   +  FKEF ++   + RCK MP+SS+ LKPMQR+T+Y LI++NIL+NT + HPD   ++ A+  A  LC  VNEG+REKENS+RLEWIQ HVQC+GL+E+L FNS TN LG RK ++SG LYKAKS KEL GFLFNDFLLL  +T    ++G   VF    S    +Q+KMYK PI LN VL+ +   PS                      IF I      + L+A S+N+R  WV+++ AAS  YIETE   RE +  +R  R+ G+GRL+V V+EG  LK   +   K++ YCE ++G+Q   TK +  T NPKWN + QF I+++E +VLC++ ++++ F+P+DFLGRTE+ + DIK+ +  +KGP+ + L L  V +GE++V+LDL  F
Sbjct:  908 GLQAQALYPWRAKKDNHLNFNKSDVITVLEQQDMWWFGEVQG--QKGWFPKSYVK-LISGPVRKSTSIDTGPTE--SPASLKRVASPAAKPAIPGEEFIAMYTYESSEQGDLTFQQGDVIVVTKKDGDWWT-GTVGDKSGVFPSNYVRL--KDSEGSGTAGKTGSLGKKPEIAQVIASYAATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVK--------------LLSPGTSKITPT--ELPKT--------AVQPAVCQVIGMYDYTAQNDDELAFSKGQIINVLNKEDPDWWKGE--VSGQVGLFPSNYVK-----LTTD--------MDPSQQ--------------WCSD--LHLLDMLTPTERKRQGYIHELIVTEENYVNDLQLVTEIFQKPLTESELLTEKEVAMIFVNWKELIMCNIKLLKALRVRKKMSGEKMPVKMIGDILSAQLPHMQPYIRFCSCQLNGAALIQQKTDEAPDFKEFVKRLAMDPRCKGMPLSSFILKPMQRVTRYPLIIKNILENTPENHPDHSHLKHALEKAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQITKPLGSSGTDKVF----SPKSNLQYKMYKTPIFLNEVLVKLPTDPSGDE------------------PIFHISHIDRVYTLRAESINERTAWVQKIKAASELYIETEKKKREKAYLVRSQRATGIGRLMVNVVEGIELKPCRS-HGKSNPYCEVTMGSQCHITKTIQDTLNPKWNSNCQFFIRDLEQEVLCITVFERDQFSPDDFLGRTEIRVADIKKDQ-GSKGPVTKCLLLHEVPTGEIVVRLDLQLF 1711          

Query:   74 GNQSQWSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEML----------------------------VPPDSFPFSDLGANEIFSSKAAPSYNEVMAKDKADRQSFREKPPIPQDIQSTFPP---LPKRTS--------------------------PQTDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSMVTI 841
            G+   W+I+ EE ++H  QF  L P+ GFI+G QA+ +  +S L   +L +IW+LAD++ DGRM   EFSIAM LIK KL+G +LP+ LP  M                             VP  S P   +G +    S   P+    +A            PP+ Q + +   P   LPK +S                          P  +W + Q+ R +YR  FN  D+   G L+G +A+ +L+QS L  + LA IWNLSDID DGKLT EEF +AM+L++ A +G+ LP  LP   +PPS   +
Sbjct:   10 GSLDVWAITVEERAKHDQQFLSLKPIAGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQGYQLPSTLPPVMKQQPVAISSAPAFGIGGIASMPPLTAVAPVPMGSIPV--VGMSPPLVSSVPPAAVPPLANGA---------PPVIQPLPAFAHPAATLPKSSSFSRSGPGSQLNTKLQKAQSFDVASAPPAAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRV 311          

Query: 1739 YQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLD-------------------------------PVQSNELVLTPD----------SETSTDKEQNVFDQ-------TLPDGATIKK------------APNNVW----------VEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQ----PVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVK--------------KLTKQDLEHAQTIDTISSDYYTALSLENSNSPTMTYDDIGRNLNDFDTDSGITDPELATPAEIGENAAY-SNYCTLAXXXXXXXXXXXXXXXLSKAKIVRA-----YSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLS 2938
            Y+ALY F  R  DE+T + GDI++V + S    P GWL G LK     G FP  Y +K+                                PV S+E   TP+          S ++   E + +D        T+P    +++            +P+ V            +A++PW    ++     L+FN    I V+E++   WW GE+             GWFP+ YV+    PV  S  T + T  T   ++L   AS     A              GE  +A+Y YES+  GDLT + GD+I +      WW G +    ++G+FPS+YV+               L K+  E AQ I + ++     L+L       +   + G          G  + EL    +  +   + +NY  L      + +      +  +  + +      Y+A + DEL+   GQ +N+++  D DW+K ++S
Sbjct:  743 YRALYPFESRSHDEITIQPGDIVMV-DESQTGEP-GWLGGELKGKT--GWFPANYAEKIPENEVPTPAKPVTDLTSAPAPKLALRETPAPLPVTSSEPSTTPNNWADFSSTWPSSSNEKPETDNWDTWAAQPSLTVPSAGQLRQRSAFTPATATGSSPSPVLGQGEKVEGLQAQALYPWRAKKDN----HLNFNKSDVITVLEQQDM-WWFGEVQGQK---------GWFPKSYVKLISGPVRKS--TSIDTGPTESPASLKRVASPAAKPA------------IPGEEFIAMYTYESSEQGDLTFQQGDVIVVTKKDGDWWTGTV--GDKSGVFPSNYVRLKDSEGSGTAGKTGSLGKKP-EIAQVIASYAATGPEQLTLAPGQLILIRKKNPG----------GWWEGELQARGKKRQIGWFPANYVKLLSPGTSKITPTELPKTAVQPAVCQVIGMYDYTAQNDDELAFSKGQIINVLNKEDPDWWKGEVS 1191          

Query: 1733 ESYQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNVFDQTLPDGATIKKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQ 2236
            E  Q +  +     ++LT   G +IL+R  +P     G L  R K  Q  G FP  YVK L P  S    +TP                LP  A     P    V  ++ +    +DE    L+F+ GQ I V+ ++  DWWKGE+            VG FP  YV+
Sbjct: 1070 EIAQVIASYAATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQI-GWFPANYVKLLSPGTSK---ITPTE--------------LPKTAV---QPAVCQVIGMYDYTAQNDDE----LAFSKGQIINVLNKEDPDWWKGEVSGQ---------VGLFPSNYVK 1203          

Query: 2375 GEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQTIDTISSDYYTALSLENSNSPTM-------------TYDDIGRNLNDFDTDSGIT----DPELATPAEIGENAAY--SNYCTLAXXXXXXXXXXXXXXXLSK----AKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNE-GWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGD-KLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLL--VTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLI-MAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIR--RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFF 4957
            G    ALYP+ +     L     D+I +++    WW G ++G  + G FP  YVK L    +  + +IDT  ++  +  SL+   SP               TY+   +    F     I     D +  T   +G+ +    SNY  L               SL K    A+++ +Y+A   ++L+  PGQ + I   +   W++ +L   G   + GW P   +               + + G  +       LP +         +QP   ++I MY Y+AQN DEL+F+K  I+ +++K++P+WW+G    +  +GLFP NYV+      + D         +PS +              W  D  ++   +LT  E++RQ YI ELI TE+ Y  DLQ V  +F +P+ +S LLT +E+  IF+NW +LI  +     AL++RK  SG K P++ +GDIL +  P+   Y+RFCS Q    AL+++K   +  FKEF ++   + RCK MP+SS+ LKPMQR+T+Y LI++NIL+NT + HPD   ++ A+  A  LC  VNEG+REKENS+RLEWIQ HVQC+GL+E+L FNS TN LG RK ++SG LYKAKS KEL GFLFNDFLLL  +T    ++G   VF    S    +Q+KMYK PI LN VL+ +   PS                      IF I      + L+A S+N+R  WV+++ AAS  YIETE   RE +  +R  R+ G+GRL+V V+EG  LK   +   K++ YCE ++G+Q   TK +  T NPKWN + QF I+++E +VLC++ ++++ F+P+DFLGRTE+ + DIK+ +  +KGP+ + L L  V +GE++V+LDL  F
Sbjct:  913 GLQAQALYPWRAKKDNHLNFNKSDVITVLEQQDMWWFGEVQG--QKGWFPKSYVK-LISGPVRKSTSIDTGPTE--SPASLKRVASPAAKPAIPGEEFIAMYTYESSEQGDLTFQQGDVIVVTKKDGDWWT-GTVGDKSGVFPSNYVRL--KDSEGSGTAGKTGSLGKKPEIAQVIASYAATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVK--------------LLSPGTSKITPT--ELPKT--------AVQPAVCQVIGMYDYTAQNDDELAFSKGQIINVLNKEDPDWWKGE--VSGQVGLFPSNYVK-----LTTD--------MDPSQQ--------------WCSD--LHLLDMLTPTERKRQGYIHELIVTEENYVNDLQLVTEIFQKPLTESELLTEKEVAMIFVNWKELIMCNIKLLKALRVRKKMSGEKMPVKMIGDILSAQLPHMQPYIRFCSCQLNGAALIQQKTDEAPDFKEFVKRLAMDPRCKGMPLSSFILKPMQRVTRYPLIIKNILENTPENHPDHSHLKHALEKAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQITKPLGSSGTDKVF----SPKSNLQYKMYKTPIFLNEVLVKLPTDPSGDE------------------PIFHISHIDRVYTLRAESINERTAWVQKIKAASELYIETEKKKREKAYLVRSQRATGIGRLMVNVVEGIELKPCRS-HGKSNPYCEVTMGSQCHITKTIQDTLNPKWNSNCQFFIRDLEQEVLCITVFERDQFSPDDFLGRTEIRVADIKKDQ-GSKGPVTKCLLLHEVPTGEIVVRLDLQLF 1716          

Query:   74 GNQSQWSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEML----------------------------VPPDSFPFSDLGANEIFSSKAAPSYNEVMAKDKADRQSFREKPPIPQDIQSTFPP---LPKRTS--------------------------PQTDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSMVTI 841
            G+   W+I+ EE ++H  QF  L P+ GFI+G QA+ +  +S L   +L +IW+LAD++ DGRM   EFSIAM LIK KL+G +LP+ LP  M                             VP  S P   +G +    S   P+    +A            PP+ Q + +   P   LPK +S                          P  +W + Q+ R +YR  FN  D+   G L+G +A+ +L+QS L  + LA IWNLSDID DGKLT EEF +AM+L++ A +G+ LP  LP   +PPS   +
Sbjct:   10 GSLDVWAITVEERAKHDQQFLSLKPIAGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQGYQLPSTLPPVMKQQPVAISSAPAFGIGGIASMPPLTAVAPVPMGSIPV--VGMSPPLVSSVPPAAVPPLANGA---------PPVIQPLPAFAHPAATLPKSSSFSRSGPGSQLNTKLQKAQSFDVASAPPAAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRV 311          

Query: 1739 YQALYKFCGRQTDELTFEAGDIILVR----NPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLD-------------------------------PVQSNELVLTPD----------SETSTDKEQNVFDQ-------TLPDGATIKK------------APNNVW----------VEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQ----PVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVK--------------KLTKQDLEHAQTIDTISSDYYTALSLENSNSPTMTYDDIGRNLNDFDTDSGITDPELATPAEIGENAAY-SNYCTLAXXXXXXXXXXXXXXXLSKAKIVRA-----YSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLS 2938
            Y+ALY F  R  DE+T + GDI++V+    + S    P GWL G LK     G FP  Y +K+                                PV S+E   TP+          S ++   E + +D        T+P    +++            +P+ V            +A++PW    ++     L+FN    I V+E++   WW GE+             GWFP+ YV+    PV  S  T + T  T   ++L   AS     A              GE  +A+Y YES+  GDLT + GD+I +      WW G +    ++G+FPS+YV+               L K+  E AQ I + ++     L+L       +   + G          G  + EL    +  +   + +NY  L      + +      +  +  + +      Y+A + DEL+   GQ +N+++  D DW+K ++S
Sbjct:  743 YRALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEP-GWLGGELKGKT--GWFPANYAEKIPENEVPTPAKPVTDLTSAPAPKLALRETPAPLPVTSSEPSTTPNNWADFSSTWPSSSNEKPETDNWDTWAAQPSLTVPSAGQLRQRSAFTPATATGSSPSPVLGQGEKVEGLQAQALYPWRAKKDN----HLNFNKSDVITVLEQQDM-WWFGEVQGQK---------GWFPKSYVKLISGPVRKS--TSIDTGPTESPASLKRVASPAAKPA------------IPGEEFIAMYTYESSEQGDLTFQQGDVIVVTKKDGDWWTGTV--GDKSGVFPSNYVRLKDSEGSGTAGKTGSLGKKP-EIAQVIASYAATGPEQLTLAPGQLILIRKKNPG----------GWWEGELQARGKKRQIGWFPANYVKLLSPGTSKITPTELPKTAVQPAVCQVIGMYDYTAQNDDELAFSKGQIINVLNKEDPDWWKGEVS 1196          

Query: 1733 ESYQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNVFDQTLPDGATIKKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQ 2236
            E  Q +  +     ++LT   G +IL+R  +P     G L  R K  Q  G FP  YVK L P  S    +TP                LP  A     P    V  ++ +    +DE    L+F+ GQ I V+ ++  DWWKGE+            VG FP  YV+
Sbjct: 1075 EIAQVIASYAATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQI-GWFPANYVKLLSPGTSK---ITPTE--------------LPKTAV---QPAVCQVIGMYDYTAQNDDE----LAFSKGQIINVLNKEDPDWWKGEVSGQ---------VGLFPSNYVK 1208          

Query: 2051 AIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGD--WWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETL------------LSTEST-------------MKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGE-------YCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQ--------TIDTISSDY---YTALSLENSNSPTMTYDDIGRNLNDFDTDSGI----TDPELATPAEIGENAAY--SNYCTLAXXXXXXXXXXXXXXXLSK--AKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNE-GWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLL---LVTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLI-MAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIR--RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFF 4957
            A++P+    E    D++SF+ G  I+V E+  G+  W  G               GWFP  YV+ V  S + L            LS  ST             + +SNL    +     A     +  + S   G+          AL  + +     L     D+I +++   +WW G + G R  G FP  YVK +   +++  +        T    S+ Y    TA  +        +Y  +      F     I     D E  T   IGE      SNY    +  +  +++ S  ++     A++  AY+A   ++LS  PGQ + I+  +   W++ +L   G   + GW P   +                          ++G  P SER+      +    ++IAMY Y A N DEL+F+K  ++ +++KD+P+WW+G      + GLFP NYV+      + D         +PS +              W  D  +     +   E++RQ YI ELI+TE+ Y +DLQ V  VF + + +S  LT  ++  IF+NW +LI  +     AL++RK   G K P+Q +GDIL +   +   Y+RFCS Q     LL++K      FKEF ++   + RCK MP+SS+ LKPMQRIT+Y L++ +IL+NT   H D   ++ A+  A  LC  VNEG+REKENS+RLEWIQ HVQC+GL E+L FNS TN LG RKL++SG LYK KS KEL  FLFNDFLL   LV      +G+  +F    +S    QF+MYK PI LN VL+ +   PS                  S   +F I      + L+  ++N+R  WV+++  AS QYI+TE   RE +   R  +++G+GRL+V V+E   LK+   P  K++ YCE S+G+Q   T+ +  T NPKWN + QF IK++  DVLCL+ +D++ F+P+DFLGRTEV +  I+  +  +KGP  RRL L  V +GE+ V+ DL  F
Sbjct:  725 ALYPF----EARNHDEMSFSSGDIIQVDEKTVGEPGWLYGSFQG---------KFGWFPCNYVEKVLSSEKALSPKKALLPPTVSLSATSTSSQPPASVTDYHNVSFSNLTVNTTWQQKSAFTRTVSPGSVSPIHGQGQAVENLKAQALCSWTAKKENHLNFSKHDVITVLEQQENWWFGEVHGGR--GWFPKSYVKLIPGNEVQRGEPEALYAAVTKKPTSTAYPVTSTAYPVGEDYIALYSYSSVEPGDLTFTEGEEILVTQKDGEWWT-GSIGERTGIFPSNYVRPKDQENFGNASKSGASNKKPEIAQVTSAYAASGTEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVK-------------------------LLG--PSSERTMPTFHAV---CQVIAMYDYMANNEDELNFSKGQLINVMNKDDPDWWQGET--NGLTGLFPSNYVK-----MTTDS--------DPSQQ--------------WCAD--LQALDTMQPTERKRQGYIHELIQTEERYMDDLQLVIEVFQKRMAESGFLTEADMALIFVNWKELIMSNTKLLRALRVRKKTGGEKMPVQMIGDILAAELSHMQAYIRFCSCQLNGATLLQQKTDEDTDFKEFLKKLASDPRCKGMPLSSFLLKPMQRITRYPLLIRSILENTPQSHVDHSSLKLALERAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLAEQLIFNSLTNCLGPRKLLHSGKLYKTKSNKELHAFLFNDFLLLTYLVRQFAAASGHEKLF----NSKSSAQFRMYKTPIFLNEVLVKLPTDPS------------------SDEPVFHISHIDRVYTLRTDNINERTAWVQKIKGASEQYIDTEKKKREKAYQARSQKTSGIGRLMVHVIEATELKACK-PNGKSNPYCEVSMGSQSYTTRTLQDTLNPKWNFNCQFFIKDLYQDVLCLTMFDRDQFSPDDFLGRTEVPVAKIRTEQ-ESKGPTTRRLLLHEVPTGEVWVRFDLQLF 1652          

Query:   62 SIMLGNQSQWSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPPDSFPF 379
            + M G  + W+I++EE ++H  QF++L P  G+I+G QA+ +  +S L   +L +IW+L+D+++DG+M   EFSIAM LIK KL+G +LP VLP  M  PP   P 
Sbjct:    7 TAMNGGPNMWAITSEERTKHDKQFDNLKPSGGYITGDQARTFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVLPPIMKQPPMFSPL 112          

Query: 1730 LESYQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPD----------SETSTD------------------------KEQNVFDQTLPDGATI-----KKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQ-----PVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQT---------IDTISSDYYTALSLENSNSPTMTYDDIGRNLNDFDTDSGITDPELATPAEIGENAAY-SNYCTLAXXXXXXXXXXXXXXXLSKAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYK 2926
            L +Y+ALY F  R  DE++F +GDII V   +      GWL G  +    FG FP  YV+K   V S+E  L+P           S TST                         ++++ F +T+  G+        +A  N+  +A+  W    E    + L+F+    I V+E++  +WW GE+             GWFP+ YV+      V       L    T K ++  +  ++  +  P+            GE  +ALY Y S  PGDLT   G+ I +      WW G I G R  G+FPS+YV+   +++  +A           I  ++S Y  + + + S +P      + +N       SG    EL    +  +   + +++  L       +      +++ +   +  Y A++ DEL+   GQ +N+++  D DW++
Sbjct:  720 LVNYRALYPFEARNHDEMSFSSGDIIQVDEKTVGE--PGWLYGSFQGK--FGWFPCNYVEK---VLSSEKALSPKKALLPPTVSLSATSTSSQPPASVTDYHNVSFSNLTVNTTWQQKSAFTRTVSPGSVSPIHGQGQAVENLKAQALCSWTAKKE----NHLNFSKHDVITVLEQQE-NWWFGEVHG---------GRGWFPKSYVKLIPGNEVQRGEPEALYAAVTKKPTSTAYPVTSTAY--PV------------GEDYIALYSYSSVEPGDLTFTEGEEILVTQKDGEWWTGSI-GER-TGIFPSNYVRPKDQENFGNASKSGASNKKPEIAQVTSAYAASGTEQLSLAPGQLILILKKN------TSGWWQGELQARGKKRQKGWFPASHVKL--LGPSSERTMPTFHAVCQVIAMYDYMANNEDELNFSKGQLINVMNKDDPDWWQ 1127          

Query:  536 SPQT---DWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGR 787
            SP+T   +W + Q  R +YR +FN  D+   G+LSG +A+  LLQS LS + LA IW L+DID DG+L  EEF +AM+L + A+AG+
Sbjct:  231 SPKTGTSEWAVPQPSRLKYRQKFNSLDKGMSGYLSGFQARNALLQSNLSQTQLATIWTLADIDGDGQLKAEEFILAMHLTDMAKAGQ 317          

Query:  551 WVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSMVT 838
            W I    R ++  QF+   +   G+++GD+A+   LQSGL   +LA+IW LSD++ DGK+  +EF +AM L++    G+ LP  LP  +  P M +
Sbjct:   16 WAITSEERTKHDKQFDNL-KPSGGYITGDQARTFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVLPPIMKQPPMFS 110          

Query:   83 SQWSISTEEFSQHRIQFEHLNP-VKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHL 298
            S+W++      ++R +F  L+  + G++SG QA+  L +S LS   L  IW+LAD+D DG++   EF +AMHL
Sbjct:  237 SEWAVPQPSRLKYRQKFNSLDKGMSGYLSGFQARNALLQSNLSQTQLATIWTLADIDGDGQLKAEEFILAMHL 309          

Query: 2051 AIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGD--WWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETL------------LSTEST-------------MKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGE-------YCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQ--------TIDTISSDY---YTALSLENSNSPTMTYDDIGRNLNDFDTDSGI----TDPELATPAEIGENAAY--SNYCTLAXXXXXXXXXXXXXXXLSK--AKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNE-GWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLL---LVTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLI-MAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIR--RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFF 4957
            A++P+    E    D++SF+ G  I+V E+  G+  W  G               GWFP  YV+ V  S + L            LS  ST             + +SNL    +     A     +  + S   G+          AL  + +     L     D+I +++   +WW G + G R  G FP  YVK +   +++  +        T    S+ Y    TA  +        +Y  +      F     I     D E  T   IGE      SNY    +  +  +++ S  ++     A++  AY+A   ++LS  PGQ + I+  +   W++ +L   G   + GW P   +                          ++G  P SER+      +    ++IAMY Y A N DEL+F+K  ++ +++KD+P+WW+G      + GLFP NYV+      + D         +PS +              W  D  +     +   E++RQ YI ELI+TE+ Y +DLQ V  VF + + +S  LT  ++  IF+NW +LI  +     AL++RK   G K P+Q +GDIL +   +   Y+RFCS Q     LL++K      FKEF ++   + RCK MP+SS+ LKPMQRIT+Y L++ +IL+NT   H D   ++ A+  A  LC  VNEG+REKENS+RLEWIQ HVQC+GL E+L FNS TN LG RKL++SG LYK KS KEL  FLFNDFLL   LV      +G+  +F    +S    QF+MYK PI LN VL+ +   PS                  S   +F I      + L+  ++N+R  WV+++  AS QYI+TE   RE +   R  +++G+GRL+V V+E   LK+   P  K++ YCE S+G+Q   T+ +  T NPKWN + QF IK++  DVLCL+ +D++ F+P+DFLGRTEV +  I+  +  +KGP  RRL L  V +GE+ V+ DL  F
Sbjct:  725 ALYPF----EARNHDEMSFSSGDIIQVDEKTVGEPGWLYGSFQG---------KFGWFPCNYVEKVLSSEKALSPKKALLPPTVSLSATSTSSQPPASVTDYHNVSFSNLTVNTTWQQKSAFTRTVSPGSVSPIHGQGQAVENLKAQALCSWTAKKENHLNFSKHDVITVLEQQENWWFGEVHGGR--GWFPKSYVKLIPGNEVQRGEPEALYAAVTKKPTSTAYPVTSTAYPVGEDYIALYSYSSVEPGDLTFTEGEEILVTQKDGEWWT-GSIGERTGIFPSNYVRPKDQENFGNASKSGASNKKPEIAQVTSAYAASGTEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVK-------------------------LLG--PSSERTMPTFHAV---CQVIAMYDYMANNEDELNFSKGQLINVMNKDDPDWWQGET--NGLTGLFPSNYVK-----MTTDS--------DPSQQ--------------WCAD--LQALDTMQPTERKRQGYIHELIQTEERYMDDLQLVIEVFQKRMAESGFLTEADMALIFVNWKELIMSNTKLLRALRVRKKTGGEKMPVQMIGDILAAELSHMQAYIRFCSCQLNGATLLQQKTDEDTDFKEFLKKLASDPRCKGMPLSSFLLKPMQRITRYPLLIRSILENTPQSHVDHSSLKLALERAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLAEQLIFNSLTNCLGPRKLLHSGKLYKTKSNKELHAFLFNDFLLLTYLVRQFAAASGHEKLF----NSKSSAQFRMYKTPIFLNEVLVKLPTDPS------------------SDEPVFHISHIDRVYTLRTDNINERTAWVQKIKGASEQYIDTEKKKREKAYQARSQKTSGIGRLMVHVIEATELKACK-PNGKSNPYCEVSMGSQSYTTRTLQDTLNPKWNFNCQFFIKDLYQDVLCLTMFDRDQFSPDDFLGRTEVPVAKIRTEQ-ESKGPTTRRLLLHEVPTGEVWVRFDLQLF 1652          

Query:   62 SIMLGNQSQWSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPPDSFPF 379
            + M G  + W+I++EE ++H  QF++L P  G+I+G QA+ +  +S L   +L +IW+L+D+++DG+M   EFSIAM LIK KL+G +LP VLP  M  PP   P 
Sbjct:    7 TAMNGGPNMWAITSEERTKHDKQFDNLKPSGGYITGDQARTFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVLPPIMKQPPMFSPL 112          

Query: 1730 LESYQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPD----------SETSTD------------------------KEQNVFDQTLPDGATI-----KKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQ-----PVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQT---------IDTISSDYYTALSLENSNSPTMTYDDIGRNLNDFDTDSGITDPELATPAEIGENAAY-SNYCTLAXXXXXXXXXXXXXXXLSKAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYK 2926
            L +Y+ALY F  R  DE++F +GDII V   +      GWL G  +    FG FP  YV+K   V S+E  L+P           S TST                         ++++ F +T+  G+        +A  N+  +A+  W    E    + L+F+    I V+E++  +WW GE+             GWFP+ YV+      V       L    T K ++  +  ++  +  P+            GE  +ALY Y S  PGDLT   G+ I +      WW G I G R  G+FPS+YV+   +++  +A           I  ++S Y  + + + S +P      + +N       SG    EL    +  +   + +++  L       +      +++ +   +  Y A++ DEL+   GQ +N+++  D DW++
Sbjct:  720 LVNYRALYPFEARNHDEMSFSSGDIIQVDEKTVGE--PGWLYGSFQGK--FGWFPCNYVEK---VLSSEKALSPKKALLPPTVSLSATSTSSQPPASVTDYHNVSFSNLTVNTTWQQKSAFTRTVSPGSVSPIHGQGQAVENLKAQALCSWTAKKE----NHLNFSKHDVITVLEQQE-NWWFGEVHG---------GRGWFPKSYVKLIPGNEVQRGEPEALYAAVTKKPTSTAYPVTSTAY--PV------------GEDYIALYSYSSVEPGDLTFTEGEEILVTQKDGEWWTGSI-GER-TGIFPSNYVRPKDQENFGNASKSGASNKKPEIAQVTSAYAASGTEQLSLAPGQLILILKKN------TSGWWQGELQARGKKRQKGWFPASHVKL--LGPSSERTMPTFHAVCQVIAMYDYMANNEDELNFSKGQLINVMNKDDPDWWQ 1127          

Query:  536 SPQT---DWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGR 787
            SP+T   +W + Q  R +YR +FN  D+   G+LSG +A+  LLQS LS + LA IW L+DID DG+L  EEF +AM+L + A+AG+
Sbjct:  231 SPKTGTSEWAVPQPSRLKYRQKFNSLDKGMSGYLSGFQARNALLQSNLSQTQLATIWTLADIDGDGQLKAEEFILAMHLTDMAKAGQ 317          

Query:  551 WVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSMVT 838
            W I    R ++  QF+   +   G+++GD+A+   LQSGL   +LA+IW LSD++ DGK+  +EF +AM L++    G+ LP  LP  +  P M +
Sbjct:   16 WAITSEERTKHDKQFDNL-KPSGGYITGDQARTFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVLPPIMKQPPMFS 110          

Query:   83 SQWSISTEEFSQHRIQFEHLNP-VKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHL 298
            S+W++      ++R +F  L+  + G++SG QA+  L +S LS   L  IW+LAD+D DG++   EF +AMHL
Sbjct:  237 SEWAVPQPSRLKYRQKFNSLDKGMSGYLSGFQARNALLQSNLSQTQLATIWTLADIDGDGQLKAEEFILAMHL 309          

Query: 2051 AIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGD--WWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETL------------LSTEST-------------MKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGE-------YCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQ--------TIDTISSDY---YTALSLENSNSPTMTYDDIGRNLNDFDTDSGI----TDPELATPAEIGENAAY--SNYCTLAXXXXXXXXXXXXXXXLSK--AKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNE-GWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLL---LVTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLI-MAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIR--RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFF 4957
            A++P+    E    D++SF+ G  I+V E+  G+  W  G               GWFP  YV+ V  S + L            LS  ST             + +SNL    +     A     +  + S   G+          AL  + +     L     D+I +++   +WW G + G R  G FP  YVK +   +++  +        T    S+ Y    TA  +        +Y  +      F     I     D E  T   IGE      SNY    +  +  +++ S  ++     A++  AY+A   ++LS  PGQ + I+  +   W++ +L   G   + GW P   +                          ++G  P SER+      +    ++IAMY Y A N DEL+F+K  ++ +++KD+P+WW+G      + GLFP NYV+      + D         +PS +              W  D  +     +   E++RQ YI ELI+TE+ Y +DLQ V  VF + + +S  LT  ++  IF+NW +LI  +     AL++RK   G K P+Q +GDIL +   +   Y+RFCS Q     LL++K      FKEF ++   + RCK MP+SS+ LKPMQRIT+Y L++ +IL+NT   H D   ++ A+  A  LC  VNEG+REKENS+RLEWIQ HVQC+GL E+L FNS TN LG RKL++SG LYK KS KEL  FLFNDFLL   LV      +G+  +F    +S    QF+MYK PI LN VL+ +   PS                  S   +F I      + L+  ++N+R  WV+++  AS QYI+TE   RE +   R  +++G+GRL+V V+E   LK+   P  K++ YCE S+G+Q   T+ +  T NPKWN + QF IK++  DVLCL+ +D++ F+P+DFLGRTEV +  I+  +  +KGP  RRL L  V +GE+ V+ DL  F
Sbjct:  752 ALYPF----EARNHDEMSFSSGDIIQVDEKTVGEPGWLYGSFQG---------KFGWFPCNYVEKVLSSEKALSPKKALLPPTVSLSATSTSSQPPASVTDYHNVSFSNLTVNTTWQQKSAFTRTVSPGSVSPIHGQGQAVENLKAQALCSWTAKKENHLNFSKHDVITVLEQQENWWFGEVHGGR--GWFPKSYVKLIPGNEVQRGEPEALYAAVTKKPTSTAYPVTSTAYPVGEDYIALYSYSSVEPGDLTFTEGEEILVTQKDGEWWT-GSIGERTGIFPSNYVRPKDQENFGNASKSGASNKKPEIAQVTSAYAASGTEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVK-------------------------LLG--PSSERTMPTFHAV---CQVIAMYDYMANNEDELNFSKGQLINVMNKDDPDWWQGET--NGLTGLFPSNYVK-----MTTDS--------DPSQQ--------------WCAD--LQALDTMQPTERKRQGYIHELIQTEERYMDDLQLVIEVFQKRMAESGFLTEADMALIFVNWKELIMSNTKLLRALRVRKKTGGEKMPVQMIGDILAAELSHMQAYIRFCSCQLNGATLLQQKTDEDTDFKEFLKKLASDPRCKGMPLSSFLLKPMQRITRYPLLIRSILENTPQSHVDHSSLKLALERAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLAEQLIFNSLTNCLGPRKLLHSGKLYKTKSNKELHAFLFNDFLLLTYLVRQFAAASGHEKLF----NSKSSAQFRMYKTPIFLNEVLVKLPTDPS------------------SDEPVFHISHIDRVYTLRTDNINERTAWVQKIKGASEQYIDTEKKKREKAYQARSQKTSGIGRLMVHVIEATELKACK-PNGKSNPYCEVSMGSQSYTTRTLQDTLNPKWNFNCQFFIKDLYQDVLCLTMFDRDQFSPDDFLGRTEVPVAKIRTEQ-ESKGPTTRRLLLHEVPTGEVWVRFDLQLF 1679          

Query:   62 SIMLGNQSQWSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPPDSFPF 379
            + M G  + W+I++EE ++H  QF++L P  G+I+G QA+ +  +S L   +L +IW+L+D+++DG+M   EFSIAM LIK KL+G +LP VLP  M  PP   P 
Sbjct:    7 TAMNGGPNMWAITSEERTKHDKQFDNLKPSGGYITGDQARTFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVLPPIMKQPPMFSPL 112          

Query: 1730 LESYQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPD----------SETSTD------------------------KEQNVFDQTLPDGATI-----KKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQ-----PVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQT---------IDTISSDYYTALSLENSNSPTMTYDDIGRNLNDFDTDSGITDPELATPAEIGENAAY-SNYCTLAXXXXXXXXXXXXXXXLSKAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYK 2926
            L +Y+ALY F  R  DE++F +GDII V   +      GWL G  +    FG FP  YV+K   V S+E  L+P           S TST                         ++++ F +T+  G+        +A  N+  +A+  W    E    + L+F+    I V+E++  +WW GE+             GWFP+ YV+      V       L    T K ++  +  ++  +  P+            GE  +ALY Y S  PGDLT   G+ I +      WW G I G R  G+FPS+YV+   +++  +A           I  ++S Y  + + + S +P      + +N       SG    EL    +  +   + +++  L       +      +++ +   +  Y A++ DEL+   GQ +N+++  D DW++
Sbjct:  747 LVNYRALYPFEARNHDEMSFSSGDIIQVDEKTVGE--PGWLYGSFQGK--FGWFPCNYVEK---VLSSEKALSPKKALLPPTVSLSATSTSSQPPASVTDYHNVSFSNLTVNTTWQQKSAFTRTVSPGSVSPIHGQGQAVENLKAQALCSWTAKKE----NHLNFSKHDVITVLEQQE-NWWFGEVHG---------GRGWFPKSYVKLIPGNEVQRGEPEALYAAVTKKPTSTAYPVTSTAY--PV------------GEDYIALYSYSSVEPGDLTFTEGEEILVTQKDGEWWTGSI-GER-TGIFPSNYVRPKDQENFGNASKSGASNKKPEIAQVTSAYAASGTEQLSLAPGQLILILKKN------TSGWWQGELQARGKKRQKGWFPASHVKL--LGPSSERTMPTFHAVCQVIAMYDYMANNEDELNFSKGQLINVMNKDDPDWWQ 1154          

Query:  536 SPQT---DWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGR 787
            SP+T   +W + Q  R +YR +FN  D+   G+LSG +A+  LLQS LS + LA IW L+DID DG+L  EEF +AM+L + A+AG+
Sbjct:  231 SPKTGTSEWAVPQPSRLKYRQKFNSLDKGMSGYLSGFQARNALLQSNLSQTQLATIWTLADIDGDGQLKAEEFILAMHLTDMAKAGQ 317          

Query:  551 WVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSMVT 838
            W I    R ++  QF+   +   G+++GD+A+   LQSGL   +LA+IW LSD++ DGK+  +EF +AM L++    G+ LP  LP  +  P M +
Sbjct:   16 WAITSEERTKHDKQFDNL-KPSGGYITGDQARTFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVLPPIMKQPPMFS 110          

Query:   83 SQWSISTEEFSQHRIQFEHLNP-VKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHL 298
            S+W++      ++R +F  L+  + G++SG QA+  L +S LS   L  IW+LAD+D DG++   EF +AMHL
Sbjct:  237 SEWAVPQPSRLKYRQKFNSLDKGMSGYLSGFQARNALLQSNLSQTQLATIWTLADIDGDGQLKAEEFILAMHL 309          

Query: 1739 YQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNVFDQTLPDGATIKKAPN-NVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQTIDTISSDYYTALSLENSNSPTM-------------TYDDIGRNLNDFDTDSGIT----DPELATPAEIGENAAY--SNYCTLAXXXXXXXXXXXXXXXLSK----AKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNE-GWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLL--VTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLI-MAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIR--RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFF 4957
            Y+ALY F  R  DE+T E GDII+V + S    P GWL G LK     G FP  Y +++ P         P +ET+     +V    +   A    + N N W +    W  +  D+               +E  + D W  +                 P + V       +    T +T+  S     + + + G               G    ALYP+ +     L     D+I +++    WW G ++G  + G FP  YVK L    L  + +ID+ SS+  +  SL+  +SP               TY+   +    F     I     D +  T   +GE      SNY  +         +     SL K    A+++ +Y+A   ++L+  PGQ + I   +   W++ +L   G   + GW P   +               + + G ++        P S         + P  ++I MY Y AQN DEL+F+K  ++ +++K++P+WW+G       +GLFP NYV+      + D         +PS +              W  D  ++   +L+  E++RQ YI ELI TE+ Y  DLQ V   F +P+ +S+LLT +E+  IF+NW +LI  +     AL++RK  SG K P++ +GDIL +  P+   Y+RFCS Q    AL+++K     +FKEF ++   + RCK MP+SS+ LKPMQR+T+Y LI++NI++NT + HPD   +++A+  A  LC  VNEG+REKENS+RLEWIQ HVQC+GL+E+L FNS TN LG RK ++SG LYKAKS KEL GFLFNDFLLL  +     ++G   VF    S    +Q+KMYK PI LN VL+ +   PS                      IF I      + L+A S+N+R  WV+++ AAS  YIETE   RE +  +R  R+ G+GRL+V ++EG  LK   T   K++ YCE ++G+Q   TK +  T NPKWN + QF IK++E DVLC++ ++++ F+P+DFLGRTE+ + DIK+ +  +KGP+ + L L  V +GE++V+LDL  F
Sbjct:  737 YRALYPFDARSHDEITIEPGDIIMV-DESQTGEP-GWLGGELKGKT--GWFPANYAERM-PESEFPSTTKPAAETTAKPTVHVAPSPVAPAAFTNTSTNSNNWADFSSTWPTNNTDK---------------VESDNWDTWAAQ-----------------PSLTVPSAGQHRQRSAFTPATVTGS-----SPSPVLG---------QGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDMWWFGEVQG--QKGWFPKSYVK-LISGPLRKSTSIDSTSSE--SPASLKRVSSPAFKPAIQGEEYISMYTYESNEQGDLTFQQGDLIVVIKKDGDWWT-GTVGEKTGVFPSNY--VRPKDSEAAGSGGKTGSLGKKPEIAQVIASYAATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVK--------------LLSPGTNKSTPTEPPKPTS---------LPPTCQVIGMYDYIAQNDDELAFSKGQVINVLNKEDPDWWKGE--LNGHVGLFPSNYVK-----LTTD--------MDPSQQ--------------WCAD--LHLLDMLSPTERKRQGYIHELIVTEENYVSDLQLVTETFQKPLLESDLLTEKEVAMIFVNWKELIMCNIKLLKALRVRKKMSGEKMPVKMIGDILTAQLPHMQPYIRFCSCQLNGAALIQQKTDEVPEFKEFVKRLAMDPRCKGMPLSSFLLKPMQRVTRYPLIIKNIIENTPENHPDHSHLKQALEKAEELCSQVNEGVREKENSDRLEWIQGHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQIIKPLGSSGNDKVF----SPKSNLQYKMYKTPIFLNEVLVKLPTDPSG------------------DEPIFHISHIDRVYTLRAESINERTAWVQKIKAASELYIETEKKKREKAYLVRSQRATGIGRLMVNIVEGIELKPCRT-HGKSNPYCEITMGSQCHITKTIQDTLNPKWNSNCQFFIKDLEQDVLCITVFERDQFSPDDFLGRTEIRVADIKKDQ-GSKGPVTKCLLLHEVPTGEIVVRLDLQLF 1702          

Query:   74 GNQSQWSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEML------------------------------VPPDSFPFSDL----------------GANEIFSSKAAPSYNEVMAKDKADRQS-----FREKPPIPQDIQSTFPPLPKRTSPQTDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSMVTISNNN 853
            GN   W+I+ EE ++H  QF  L P  G+I+G QA+ +  +S L   +L +IW+LAD++ DGRM   EFSIAM LIK KL+G  LP++LP  ML                              VP  S P   +                GA  +  S  A +++  + K  +  +S        K    Q      PPL        +W +  + R +YR  FN QD+   G L+G +A+ +L+QS L  S LA IWNLSDID DGKLT EEF +AM+L++ A +G+ LP  LP   +PPS   + + +
Sbjct:   10 GNLDIWAITVEERAKHDQQFHGLKPTAGYITGDQARNFFLQSGLPQPVLAQIWALADMNNDGRMDQLEFSIAMKLIKLKLQGYPLPSILPSNMLKQPVAMPAAAVAGFGMSGIVGIPPLAAVAPVPMPSIPVVGMSPPLVSSVPTVPPLSNGAPAVIQSHPAFAHSATLPKSSSFGRSVAGSQINTKLQKAQSFDVPAPPL------VVEWAVPSSSRLKYRQLFNSQDKTMSGNLTGPQARTILMQSSLPQSQLATIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPILPPEYIPPSFRRVRSGS 314          

Query: 1733 ESYQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNVFDQTLPDGATIKKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQ 2236
            E  Q +  +     ++LT   G +IL+R  +P     G L  R K  Q  G FP  YVK L P  +      P   TS                     P    V  ++ +I   +DE    L+F+ GQ I V+ ++  DWWKGE+  H         VG FP  YV+
Sbjct: 1061 EIAQVIASYAATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQI-GWFPANYVKLLSPGTNKSTPTEPPKPTSL--------------------PPTCQVIGMYDYIAQNDDE----LAFSKGQVINVLNKEDPDWWKGELNGH---------VGLFPSNYVK 1194          

Query: 2375 GEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQTIDTISSDYYTALSLENSNSPTM-------------TYDDIGRNLNDFDTDSGIT----DPELATPAEIGENAAY--SNYCTLAXXXXXXXXXXXXXXXLSK----AKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNE-GWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGD-KLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLL--VTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLI-MAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIR--RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFF 4957
            G    ALYP+ +     L     D+I +++    WW G ++G  + G FP  YVK L    +  + +IDT  ++  +  SL+   SP               TY+   +    F     I     D +  T   +G+ +    SNY  L               SL K    A+++ +Y+A   ++L+  PGQ + I   +   W++ +L   G   + GW P   +               + + G  +       LP +         +QP   ++I MY Y+AQN DEL+F+K  I+ +++K++P+WW+G    +  +GLFP NYV+      + D         +PS +              W  D  ++   +LT  E++RQ YI ELI TE+ Y  DLQ V  +F +P+ +S LLT +E+  IF+NW +LI  +     AL++RK  SG K P++ +GDIL +  P+   Y+RFCS Q    AL+++K   +  FKEF ++   + RCK MP+SS+ LKPMQR+T+Y LI++NIL+NT + HPD   ++ A+  A  LC  VNEG+REKENS+RLEWIQ HVQC+GL+E+L FNS TN LG RK ++SG LYKAKS KEL GFLFNDFLLL  +T    ++G   VF    S    +Q+KMYK PI LN VL+ +   PS                      IF I      + L+A S+N+R  WV+++ AAS  YIETE   RE +  +R  R+ G+GRL+V V+EG  LK   +   K++ YCE ++G+Q   TK +  T NPKWN + QF I+++E +VLC++ ++++ F+P+DFLGRTE+ + DIK+ +  +KGP+ + L L  V +GE++V+LDL  F
Sbjct:  908 GLQAQALYPWRAKKDNHLNFNKSDVITVLEQQDMWWFGEVQG--QKGWFPKSYVK-LISGPVRKSTSIDTGPTE--SPASLKRVASPAAKPAIPGEEFIAMYTYESSEQGDLTFQQGDVIVVTKKDGDWWT-GTVGDKSGVFPSNYVRL--KDSEGSGTAGKTGSLGKKPEIAQVIASYAATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVK--------------LLSPGTSKITPT--ELPKT--------AVQPAVCQVIGMYDYTAQNDDELAFSKGQIINVLNKEDPDWWKGE--VSGQVGLFPSNYVK-----LTTD--------MDPSQQ--------------WCSD--LHLLDMLTPTERKRQGYIHELIVTEENYVNDLQLVTEIFQKPLTESELLTEKEVAMIFVNWKELIMCNIKLLKALRVRKKMSGEKMPVKMIGDILSAQLPHMQPYIRFCSCQLNGAALIQQKTDEAPDFKEFVKRLAMDPRCKGMPLSSFILKPMQRVTRYPLIIKNILENTPENHPDHSHLKHALEKAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQITKPLGSSGTDKVF----SPKSNLQYKMYKTPIFLNEVLVKLPTDPSGDE------------------PIFHISHIDRVYTLRAESINERTAWVQKIKAASELYIETEKKKREKAYLVRSQRATGIGRLMVNVVEGIELKPCRS-HGKSNPYCEVTMGSQCHITKTIQDTLNPKWNSNCQFFIRDLEQEVLCITVFERDQFSPDDFLGRTEIRVADIKKDQ-GSKGPVTKCLLLHEVPTGEIVVRLDLQLF 1711          

Query:   74 GNQSQWSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEML----------------------------VPPDSFPFSDLGANEIFSSKAAPSYNEVMAKDKADRQSFREKPPIPQDIQSTFPP---LPKRTS--------------------------PQTDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSMVTI 841
            G+   W+I+ EE ++H  QF  L P+ GFI+G QA+ +  +S L   +L +IW+LAD++ DGRM   EFSIAM LIK KL+G +LP+ LP  M                             VP  S P   +G +    S   P+    +A            PP+ Q + +   P   LPK +S                          P  +W + Q+ R +YR  FN  D+   G L+G +A+ +L+QS L  + LA IWNLSDID DGKLT EEF +AM+L++ A +G+ LP  LP   +PPS   +
Sbjct:   10 GSLDVWAITVEERAKHDQQFLSLKPIAGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQGYQLPSTLPPVMKQQPVAISSAPAFGIGGIASMPPLTAVAPVPMGSIPV--VGMSPPLVSSVPPAAVPPLANGA---------PPVIQPLPAFAHPAATLPKSSSFSRSGPGSQLNTKLQKAQSFDVASAPPAAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRV 311          

Query: 1739 YQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLD-------------------------------PVQSNELVLTPD----------SETSTDKEQNVFDQ-------TLPDGATIKK------------APNNVW----------VEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQ----PVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVK--------------KLTKQDLEHAQTIDTISSDYYTALSLENSNSPTMTYDDIGRNLNDFDTDSGITDPELATPAEIGENAAY-SNYCTLAXXXXXXXXXXXXXXXLSKAKIVRA-----YSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLS 2938
            Y+ALY F  R  DE+T + GDI++V + S    P GWL G LK     G FP  Y +K+                                PV S+E   TP+          S ++   E + +D        T+P    +++            +P+ V            +A++PW    ++     L+FN    I V+E++   WW GE+             GWFP+ YV+    PV  S  T + T  T   ++L   AS     A              GE  +A+Y YES+  GDLT + GD+I +      WW G +    ++G+FPS+YV+               L K+  E AQ I + ++     L+L       +   + G          G  + EL    +  +   + +NY  L      + +      +  +  + +      Y+A + DEL+   GQ +N+++  D DW+K ++S
Sbjct:  743 YRALYPFESRSHDEITIQPGDIVMV-DESQTGEP-GWLGGELKGKT--GWFPANYAEKIPENEVPTPAKPVTDLTSAPAPKLALRETPAPLPVTSSEPSTTPNNWADFSSTWPSSSNEKPETDNWDTWAAQPSLTVPSAGQLRQRSAFTPATATGSSPSPVLGQGEKVEGLQAQALYPWRAKKDN----HLNFNKSDVITVLEQQDM-WWFGEVQGQK---------GWFPKSYVKLISGPVRKS--TSIDTGPTESPASLKRVASPAAKPA------------IPGEEFIAMYTYESSEQGDLTFQQGDVIVVTKKDGDWWTGTV--GDKSGVFPSNYVRLKDSEGSGTAGKTGSLGKKP-EIAQVIASYAATGPEQLTLAPGQLILIRKKNPG----------GWWEGELQARGKKRQIGWFPANYVKLLSPGTSKITPTELPKTAVQPAVCQVIGMYDYTAQNDDELAFSKGQIINVLNKEDPDWWKGEVS 1191          

Query: 2375 GEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQTIDT--------------------ISSDYYTAL-SLENSNSPTMTY---DDIGRNLNDFDTDSGITDPELATPAEIGENAAY--SNYCTLAXXXXXXXXXXXXXXXLSK----AKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNE-GWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGD-KLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLL--VTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLI-MAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIR--RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFF 4957
            G    ALYP+ +     L     D+I +++    WW G ++G  + G FP  YVK L    +  + +IDT                    I  + + A+ + E+S    +T+   D I     D D  +G           +GE +    SNY  L               SL K    A+++ +Y+A   ++L+  PGQ + I   +   W++ +L   G   + GW P   +               + + G  +       LP +         +QP   ++I MY Y+AQN DEL+F+K  I+ ++SK++P+WW+G    +  +GLFP NYV+      + D         +PS +              W  D  ++   +LT  E++RQ YI ELI TE+ Y  DLQ V  +F +P+ +S LLT +E+  IF+NW +LI  +     AL++RK  SG K P++ +GDIL +  P+   Y+RFCS Q    AL+++K   +  FKEF ++   + RCK MP+SS+ LKPMQR+T+Y LI++NIL+NT + HPD   ++ A+  A  LC  VNEG+REKENS+RLEWIQ HVQC+GL+E+L FNS TN LG RK ++SG LYKAKS KEL GFLFNDFLLL  +T    ++    VF    S    +Q+KMYK PI LN VL+ +   PS                      IF I      + L+A S+N+R  WV+++ AAS  YIETE   RE +  +R  R+ G+GRL+V V+EG  LK   +   K++ YCE ++G+Q   TK +  T NPKWN + QF I+++E +VLC++ ++++ F+P+DFLGRTE+ + DIK+ +  +KGP+ + L L  V +GE++V+LDL  F
Sbjct:  907 GLQAQALYPWRAKKDNHLNFNKSDVITVLEQQDMWWFGEVQG--QKGWFPKSYVK-LISGPVRKSTSIDTGPTEAPSSLKRVASPAAKPAIPGEEFVAMYTYESSEHGDLTFQQGDVIVVTKKDGDWWTGT----------VGETSGVFPSNYVRL--KDSEGSGTAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVK--------------LLSPGTSKITPT--ELPKT--------AVQPAVCQVIGMYDYTAQNDDELAFSKGQIINVLSKEDPDWWKGE--VSGQVGLFPSNYVK-----LTTD--------MDPSQQ--------------WCSD--LHLLDMLTPTERKRQGYIHELIVTEENYVNDLQLVTEIFQKPLTESELLTEKEVAMIFVNWKELIMCNIKLLKALRVRKKMSGEKMPVKMIGDILSAQLPHMQPYIRFCSCQLNGAALIQQKTDEAPDFKEFVKRLAMDPRCKGMPLSSFILKPMQRVTRYPLIIKNILENTPENHPDHSHLKHALEKAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQITKPLGSSSTDKVF----SPKSNLQYKMYKTPIFLNEVLVKLPTDPSGDE------------------PIFHISHIDRVYTLRAESINERTAWVQKIKAASELYIETEKKKREKAYLVRSQRATGIGRLMVNVVEGIELKPCRS-HGKSNPYCEVTMGSQCHITKTIQDTLNPKWNSNCQFFIRDLEQEVLCITVFERDQFSPDDFLGRTEIRVADIKKDQ-GSKGPVTKCLLLHEVPTGEIVVRLDLQLF 1710          

Query:   74 GNQSQWSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPPDSFPFSDLGANEIFSSKAAPSYNEVMAKDKADRQSFREKPPIPQDI-QSTFPPL----------------PKRTSPQTD-------------------------------WVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSMVTISNNNKSLPNSHTEHEWTATSESRPGTLKACPASPQIIQETSMNTAQWNKPLPVTPEIEIQSQIHQ-KLEKEKQRLIDLEETRLQQAVXXXXXXXXXXXXXXDRQE 1153
            G+   W+I+ EE ++H  QF+ L P+ GFI+G QA+ +  +S L   +L +IW+LAD+++DGRM   EFSIAM LIK KL+G +LP  LP  M   P +   S   A  I      P    V              PP+   + Q+  PPL                P  T P++                                W + Q+ R +YR  FN  D+   G L+G +A+ +L+QS L  + LA IWNLSDID DGKLT EEF +AM+L++ A +G+ LP  LP   +PPS   + + +     S +  +            +  P  P     +S +  Q  K LPVT E + +    +  LE EK+R   LE+ R +Q    +    E  +K ++RQE
Sbjct:   10 GSLDIWAITVEERAKHDQQFQSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNKDGRMDQVEFSIAMKLIKLKLQGYQLPPALPPVMKQQPAAI--SSAPAFGIGGMAGMPPLTAVAPVPMGSIPVVGMSPPLVSSVPQAAVPPLANGAPPVIQPLPAFAHPAATLPKSSSFSRSGPGSQLNTKLQKAQSFDVASAPAAAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGMSVISSSSAD------------QRLPEEP-----SSEDEQQVEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQE 399          

Query: 1739 YQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLD-------------------------------PVQSNELVLTPD----------SETSTDKEQNVFDQ-------TLPDGATIKK------------APNNVW----------VEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQ----PVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQTIDTISS-----------DYYTALSLENSNSPTMTYDDIGRNLNDFDTDSGITDPELATPAEIGENAAY-SNYCTLAXXXXXXXXXXXXXXXLSKAKIVRA-----YSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLS 2938
            Y+ALY F  R  DE+T + GDI++V + S    P GWL G LK     G FP  Y +K+                                PV S+E   TP+          S T+   E + +D        T+P    +++            +P+ V            +A++PW    ++     L+FN    I V+E++   WW GE+             GWFP+ YV+    PV  S  T + T  T   S+L   AS     A              GE  +A+Y YES+  GDLT + GD+I +      WW G +     +G+FPS+YV+    +D E + T     S             YTA   E      +T       L       G  + EL    +  +   + +NY  L      + +      +  +  + +      Y+A + DEL+   GQ +N++   D DW+K ++S
Sbjct:  742 YRALYPFESRSHDEITIQPGDIVMV-DESQTGEP-GWLGGELKGKT--GWFPANYAEKIPENEIPTPAKPVTDLTSAPAPKLALRETPAPLPVTSSEPSTTPNNWADFSSTWPSSTNEKPETDNWDTWAAQPSLTVPSAGQLRQRSAFTPATATGSSPSPVLGQGEKVEGLQAQALYPWRAKKDN----HLNFNKSDVITVLEQQDM-WWFGEVQGQK---------GWFPKSYVKLISGPVRKS--TSIDTGPTEAPSSLKRVASPAAKPA------------IPGEEFVAMYTYESSEHGDLTFQQGDVIVVTKKDGDWWTGTV--GETSGVFPSNYVR---LKDSEGSGTAGKTGSLGKKPEIAQVIASYTATGPEQ-----LTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLLSPGTSKITPTELPKTAVQPAVCQVIGMYDYTAQNDDELAFSKGQIINVLSKEDPDWWKGEVS 1190          

Query: 2375 GEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQTIDTISSDYYTALSLENSNSPTM-------------TYDDIGRNLNDFDTDSGI----TDPELATPAEIGENAAY--SNYCTLAXXXXXXXXXXXXXXXLSK----AKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNE-GWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLL--VTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLI-MAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIR--RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFF 4957
            G    ALYP+ +     L     D+I +++    WW G ++G  + G FP  YVK L    +  + ++D+ SS+  +  SL+   SP               TY+   +    F     I     D +  T   +G+ A    SNY  L               SL K    A+++ +Y+A   ++L+  PGQ + I   +   W++ +L   G   + GW P                      + Y + L+  G+  ++         +    ++I MY Y+AQN DEL+F K  I+ +++K++P+WW+G       +GLFP NYV+      + D         +PS +              W  D  ++   +LT  E++RQ YI ELI TE+ Y  DLQ V  +F +P+ +S LLT +E+  IF+NW +LI  +     AL++RK  SG K P++ +GDIL +  P+   Y+RFCS Q    AL+++K   +  FKEF ++   + RCK MP+SS+ LKPMQR+T+Y LI++NIL+NT + HPD   ++ A+  A  LC  VNEG+REKENS+RLEWIQ HVQC+GL+E+L FNS TN LG RK ++SG LYKAKS KEL GFLFNDFLLL  +T    ++G   VF    S    +Q+KMYK PI LN VL+ +   PS                      IF I      + L+A S+N+R  WV+++ AAS  YIETE   RE +  +R  R+ G+GRL+V V+EG  LK   +   K++ YCE ++G+Q   TK +  T NPKWN + QF I+++E +VLC++ ++++ F+P+DFLGRTE+ + DIK+ +  +KGP+ + L L  V +GE++V+LDL  F
Sbjct:  915 GLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDMWWFGEVQG--QKGWFPKSYVK-LISGPIRKSTSMDSGSSE--SPASLKRVASPAAKPVVSGEEFIAMYTYESSEQGDLTFQQGDVILVTKKDGDWWT-GTVGDKAGVFPSNYVRL--KDSEGSGTAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFP----------------------ANYVKLLSP-GTSKITPTEPPKSTALAAVCQVIGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGE--VNGQVGLFPSNYVK-----LTTD--------MDPSQQ--------------WCSD--LHLLDMLTPTERKRQGYIHELIVTEENYVNDLQLVTEIFQKPLMESELLTEKEVAMIFVNWKELIMCNIKLLKALRVRKKMSGEKMPVKMIGDILSAQLPHMQPYIRFCSRQLNGAALIQQKTDEAPDFKEFVKRLAMDPRCKGMPLSSFILKPMQRVTRYPLIIKNILENTPENHPDHSHLKHALEKAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQITKPLGSSGTDKVF----SPKSNLQYKMYKTPIFLNEVLVKLPTDPSGDE------------------PIFHISHIDRVYTLRAESINERTAWVQKIKAASELYIETEKKKREKAYLVRSQRATGIGRLMVNVVEGIELKPCRS-HGKSNPYCEVTMGSQCHITKTIQDTLNPKWNSNCQFFIRDLEQEVLCITVFERDQFSPDDFLGRTEIRVADIKKDQ-GSKGPVTKCLLLHEVPTGEIVVRLDLQLF 1718          

Query:   74 GNQSQWSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPP------DSFPFSDLGANEIFSSKAAPSYNEV----MAKDKADRQSFREKPPIPQDIQSTFPPLP---------------KRTSPQT---------------------DWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSMVTISNNNKSLPNSHTEHEWTATSESRPGTLKACPASPQIIQETSMNTAQWNKPLPVTPEIEIQSQIHQ-KLEKEKQRLIDLEETRLQQAVXXXXXXXXXXXXXXDRQE 1153
            G+   W+I+ EE ++H  QF  L P+ GFI+G QA+ +  +S L   +L +IW+LAD++ DGRM   EFSIAM LIK KL+G +LP+ LP  M   P       +F    + +    ++ A      +    M+            PP+         PLP                R+ P +                     +W + Q+ R +YR  FN  D+   G L+G +A+ +L+QS L  + LA IWNLSDID DGKLT EEF +AM+L++ A +G+ LP  LP   +PPS   + + +     S T  +            +  P  P +  E      Q  K LPVT E + +    +  LE EK+R   LE+ R +Q    +    E  +K ++RQE
Sbjct:   10 GSLDIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQGYQLPSALPPVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLANGAPPVIQPLPAFAHPAATLPKSSSFSRSGPGSQLNTKLQKAQSFDVASVPPVAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGISVISSTSVD------------QRLPEEPVLEDEQQ----QLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQE 400          

Query: 1733 ESYQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNVFDQTLPDGATIKKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMS-THWWKGHIRGARENGMFPSHYVKKLTKQD 2557
            E + A+Y +   +  +LTF+ GD+ILV           W  G   +    G+FP+ YV+              DSE S          T     ++ K P    V A +          P+QL+   GQ I + ++  G WW+GE+    +  G    +GWFP  YV+ +      +  TE     +    AA   + G                     +Y Y +    +L    G II +++     WWKG + G  + G+FPS+YVK  T  D
Sbjct: 1005 EEFIAMYTYESSEQGDLTFQQGDVILV-----TKKDGDWWTG--TVGDKAGVFPSNYVR------------LKDSEGSG---------TAGKTGSLGKKPEIAQVIASY------TATGPEQLTLAPGQLILIRKKNPGGWWEGEL----QARGKKRQIGWFPANYVKLLSPGTSKITPTEPPKSTA---LAAVCQVIG---------------------MYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNG--QVGLFPSNYVKLTTDMD 1216          

Query: 2045 VEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVK--------------KLTKQDLEHAQTIDTISSDYYTALSLENSNSPTMTYDDIGRNLNDFDTDSGITDPELATPAEIGENAAY-SNYCTLAXXXXXXXXXXXXXXXLSKAKIVRA-----YSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTN 2956
             +A++PW    ++     L+FN    I V+E++   WW GE+             GWFP+ YV+ +        S +S    S  +          P+            GE  +A+Y YES+  GDLT + GD+I +      WW G +    + G+FPS+YV+               L K+  E AQ I + ++     L+L       +   + G          G  + EL    +  +   + +NY  L      + +      S + A + +      Y+A + DEL+   GQ +N+++  D DW+K +  +NG   
Sbjct:  918 AQALYPWRAKKDN----HLNFNKNDVITVLEQQDM-WWFGEVQGQK---------GWFPKSYVKLISGPIRKSTSMDSGSSESPASLKRVASPAAKPVVS----------GEEFIAMYTYESSEQGDLTFQQGDVILVTKKDGDWWTGTV--GDKAGVFPSNYVRLKDSEGSGTAGKTGSLGKKP-EIAQVIASYTATGPEQLTLAPGQLILIRKKNPG----------GWWEGELQARGKKRQIGWFPANYVKLLSPGTSKITPTEPPKSTALAAVCQVIGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGE--VNGQVG 1202          

Query: 2051 AIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGD--WWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYS-NETLLSTESTM-------------------------------KYSNLNFAASNDIFGAPIXXXXXXXXXXXXGE-------YCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQTIDTISSDYYTALSLENSNSPTMTYDDIGRNLNDFDTDSGITDPELA-TPAE---------------IGENAAY--SNYCTLAXXXXXXXXXXXXXXXLSK--AKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNE-GWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTV-VGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLL---VTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLI-MAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIR--RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFF 4957
            A++P+    E    D++SFN G  I+V E+  G+  W  G    +          GWFP  YV+ +  S NE  +S +  +                                +SNL    S     A     +  + S   G+          AL  + +     L     DII +++   +WW G + G R  G FP  YVK +   +++  +           AL    +  PT     +G         S +   +L  T  E               IG+ +    SNY    +      ++ S  ++     A++  AY A   ++LS  PGQ + I+  +   W++ +L   G   + GW P   +                          ++G  P SER+        P  ++IAMY Y+A N DELSF+K  ++ +++KD+P+WW+G      + GLFP NYV+      + D         +PS +      T+   +PI                 E++RQ YI ELI+TE+ Y  DLQ V  VF + + +S  LT  E+  IF+NW +LI  +     AL++RK   G K P+Q +GDIL +   +   Y+RFCS Q    ALL++K      FKEF ++   + RCK MP+SS+ LKPMQRIT+Y L++ +IL+NT + H D   ++ A+  A  LC  VNEG+REKENS+RLEWIQ HVQC+GL E+L FNS TN LG RKL++SG LYK KS KEL GFLFNDFLLL   V     ++G   +F    SS    QFKMYK PI LN VL+ +   PS                  S   +F I      + L+  ++N+R  WV+++ AAS QYI+TE   RE +   R  +++G+GRL+V V+E   LK+   P  K++ YCE S+G+Q   T+ +  T NPKWN + QF IK++  DVLCL+ +D++ F+P+DFLGRTE+ +  I+  +  +KGP+ RRL L  V +GE+ V+ DL  F
Sbjct:  764 ALYPF----EARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGN---------FGWFPCNYVEKMPSSENEKAVSPKKALLPPTVSLSATSTSSEPLSSNQPASVTDYQNVSFSNLTVNTSWQKKSAFTRTVSPGSVSPIHGQGQVVENLKAQALCSWTAKKDNHLNFSKHDIITVLEQQENWWFGEVHGGR--GWFPKSYVKIIPGSEVKREEP---------EALYAAVNKKPTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEEILVTQKDGEWWTGSIGDRSGIFPSNYVKPKDQESFGSASKSGASNKKPEIAQVTSAYVASGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVK-------------------------LLG--PSSERA---TPAFHPVCQVIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGE--INGVTGLFPSNYVK-----MTTDS--------DPSQQWCADLQTLDTMQPI-----------------ERKRQGYIHELIQTEERYMADLQLVVEVFQKRMAESGFLTEGEMALIFVNWKELIMSNTKLLKALRVRKKTGGEKMPVQMIGDILAAELSHMQAYIRFCSCQLNGAALLQQKTDEDTDFKEFLKKLASDPRCKGMPLSSFLLKPMQRITRYPLLIRSILENTPESHADHSSLKLALERAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLAEQLIFNSLTNCLGPRKLLHSGKLYKTKSNKELHGFLFNDFLLLTYMVKQFAVSSGSEKLF----SSKSNAQFKMYKTPIFLNEVLVKLPTDPS------------------SDEPVFHISHIDRVYTLRTDNINERTAWVQKIKAASEQYIDTEKKKREKAYQARSQKTSGIGRLMVHVIEATELKACK-PNGKSNPYCEISMGSQSYTTRTIQDTLNPKWNFNCQFFIKDLYQDVLCLTLFDRDQFSPDDFLGRTEIPVAKIRTEQ-ESKGPMTRRLLLHEVPTGEVWVRFDLQLF 1691          

Query: 1730 LESYQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPD----------SETSTDKE-------------QNV----------------FDQTLPDGATI-----KKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQT---------IDTISSDYYTALSLENSNSPTMTYDDIGRNLNDFDTDSGITDPELATPAEIGENAAY-SNYCTLAXXXXXXXXXXXXXXXLSKAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTN 2956
            L +Y+ALY F  R  DE++F +GDII V   +      GWL G  + N  FG FP  YV+K+ P   NE  ++P           S TST  E             QNV                F +T+  G+        +   N+  +A+  W    ++     L+F+    I V+E++  +WW GE+             GWFP+ YV+ +  S   +   E    Y+ +N   ++  +                GE  +ALYPY S  PGDLT   G+ I +      WW G I G R +G+FPS+YVK   ++    A           I  ++S Y  + S + S +P      + +N       SG    EL    +  +   + +++  L       +      + + +   +  Y+A++ DELS   GQ +N+++  D DW++ +  ING T 
Sbjct:  759 LVNYRALYPFEARNHDEMSFNSGDIIQVDEKTVGE--PGWLYGSFQGN--FGWFPCNYVEKM-PSSENEKAVSPKKALLPPTVSLSATSTSSEPLSSNQPASVTDYQNVSFSNLTVNTSWQKKSAFTRTVSPGSVSPIHGQGQVVENLKAQALCSWTAKKDN----HLNFSKHDIITVLEQQE-NWWFGEVHG---------GRGWFPKSYVKIIPGSE--VKREEPEALYAAVNKKPTSAAYSV--------------GEEYIALYPYSSVEPGDLTFTEGEEILVTQKDGEWWTGSI-GDR-SGIFPSNYVKPKDQESFGSASKSGASNKKPEIAQVTSAYVASGSEQLSLAPGQLILILKKN------TSGWWQGELQARGKKRQKGWFPASHVKL--LGPSSERATPAFHPVCQVIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGE--INGVTG 1174          

Query:   62 SIMLGNQSQWSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPPDSFPF 379
            + M G  + W+I++EE ++H  QF++L P  G+I+G QA+ +  +S L   +L +IW+L+D+++DG+M   EFSIAM LIK KL+G +LP VLP  M  PP   P 
Sbjct:    7 TAMNGGPNMWAITSEERTKHDRQFDNLKPSGGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVLPPIMKQPPMFSPL 112          

Query:  536 SPQT---DWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGR 787
            SP+T   +W + Q  R +YR +FN  D++  G+LSG +A+  LLQS LS + LA IW L+D+D DG+L  EEF +AM+L + A+AG+
Sbjct:  230 SPKTGTSEWAVPQPTRLKYRQKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLATIWTLADVDGDGQLKAEEFILAMHLTDMAKAGQ 316          

Query:  551 WVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSMVT 838
            W I    R ++  QF+   +   G+++GD+A+   LQSGL   +LA+IW LSD++ DGK+  +EF +AM L++    G+ LP  LP  +  P M +
Sbjct:   16 WAITSEERTKHDRQFDNL-KPSGGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVLPPIMKQPPMFS 110          

Query:   83 SQWSISTEEFSQHRIQFEHLN-PVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHL 298
            S+W++      ++R +F  L+  + G++SG QA+  L +S LS   L  IW+LADVD DG++   EF +AMHL
Sbjct:  236 SEWAVPQPTRLKYRQKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLATIWTLADVDGDGQLKAEEFILAMHL 308          

Query: 1646 EKQTQNNDVKPIFDFHQTNGHKLPDEFDLESYQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLD-----PVQSNELVLTPDSETSTDK---EQNVFDQTLPDGATI-----------------KKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTES-----TMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGE-YCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQTIDTISSDYYTALSLENSNSPTMTYDDIGRNLNDFDTDSGITDPELATPAEIGENAAYSNYCTLAXXXXXXXXXXXXXXXLSKAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNE-GWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLLVTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLIMAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMS----------------------------IRRSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFF 4957
            + QTQN+     F   +  G K         ++ALYKF  R  DEL+ E GDI+ V   +      GW+ G  + N   G FP  YV K +      V  ++  +T  +ET +++   +Q V        A+                   ++  ++  +A++PW    ++     L+FN G  I V+E++   WW G++  H +       +GWFP+ YV+ +  +     S  S     T +   ++   S+     P + +   T     G+   +A+Y Y S   GDL+   GDII I      WW G +    + G+FP++YVKK+  Q  E+ +  D  S     AL    +  P  +    G+             PE+A+                                     ++ AY+A   ++LS  PGQ +++   S   W++ +L   G   + GW P   +       +   ++   T  G       +G    +   ++    ++  D+++A+YPY+AQN DEL+F K++I+ +I++D+ +WW+G        G+FP NYV+       +D  + S    NPS             P SW  D VV  N   +E E +RQ  I+EL+ TE++Y  D+  V  VFY P+ ++ +LTL EL  IF+NW +LI  +     ++++RK  SG+  PI  +GDIL  N P+   Y+RFCS Q  A  L++KK + S +FKE  ++C  + R K MP+SS+ LKPMQRITKY L++E ILK T + HPD     +A+ AA+ LC+ VNEG+RE+ENS +LEWIQ+HVQC+GL EK+ FNS TN LG RKL+YSGT+YKAKS KELVGFLFNDFLLLV P          F  +  +  K+ +KMYK PI LN V + A   + ++ +                 +F +      +  K+L+  +RD WV+++ AAS +Y+ET+   RE + S                            +R+   VGRLLV ++EG NLK+      K+  YCE S+G+Q  +TKV++ST NPKWN  MQF +K+++ DVLC++ +D++ F PNDFLGRTE+ + DI +     KGP+ +RL L  V  GE++VKLD+  F
Sbjct:  785 QSQTQNDTWADAFSSAKKKGVK---------HKALYKFEARNADELSLETGDIVQVFLDTTGE--PGWVQG--EKNGQVGWFPEAYVGKAEEDDVPSVGPDQNTVTTSNETHSNQDMGQQQVVSHLSTSEASSFTAVAQHAEANQQQQQPAESSESLQAQALYPWRAKKDN----HLTFNKGDVITVLEQQDM-WWSGKL--HGK-------IGWFPKSYVKLIGQAPAADSSASSEVSAVTSEQEIVSDERSDTPVNPPPAVDLKITVEPPQGDDLYVAMYNYISGEAGDLSFNQGDIITITSKDGDWWTGTLND--KTGIFPANYVKKMESQG-ENGEDTDMFS---LGALLPAVTARPAPSLKLAGKK------------PEIAS-------------------------------------VIAAYTATGEEQLSLKPGQLIHVRKKSPSGWWEGELQARGQKKKIGWFPANYVK------LLGSSSARSTPVGDGSKSNTLGRSTPTPTPEQAPQPVEAADQVVALYPYTAQNDDELTFQKDAIINVINRDDQDWWKGE--LNGQEGVFPANYVQ-----PVSDMRLAS----NPSPA-----------PTSWTSDPVVLANT--SETEIQRQNCIQELLSTEESYNADMSIVLDVFYRPLAEAKVLTLAELDSIFVNWKELIVCNTKLNKSMRVRKKMSGSA-PIHIIGDILCENLPHLTPYIRFCSRQLTAATLIQKKTENSPQFKEVAKKCSTDHRTKGMPLSSFLLKPMQRITKYPLMIEKILKYTPEEHPDYQYCLDALQAAKELCDQVNEGVREQENSSKLEWIQNHVQCEGLPEKITFNSVTNCLGPRKLLYSGTIYKAKSNKELVGFLFNDFLLLVQPQRPLGSVVSTFSFDPET--KVHYKMYKTPIFLNEVAVKAPQGAEEDPT-----------------VFQLSHIDRWYSFKSLTQLERDSWVKKIAAASKEYLETDRRKRERAYSLAKKMPRGVGRLLVIVQEGKNLVASDANVRKVPAVGRLLVVIVEGCNLKTHGN-TGKSDPYCEVSMGSQEHKTKVINSTLNPKWNSSMQFTVKDVKEDVLCITVFDRDLFTPNDFLGRTEIRIADILKENKEKKGPVTKRLLLHEVEKGEVVVKLDIQLF 1815          

Query:   89 WSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPPD----------------------SFPFSDLGANEIFSSKAAPSYNEVMAKDKADRQSFREKPPIPQDIQSTFPPLPKRT---------------SPQTDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPS 829
            W I+ E+ S+H  QF  L PV GFI+G QA+ +  +S L  Q+LG+IW+LAD++ DG+M   EFSIAMHLIK KL+G+ELP VLP  +   P                         P S           A PSY  V+A       +      +P    ++ P    +T               S   +W + Q  + +Y   FN  DR K+G+L G EA+ +L+ +GL + ILAQIWNLSDID DGKLT EEFC+AM+L + A++G+ LP+ LP  L+PPS
Sbjct:   13 WRITVEDRSKHDAQFFQLKPVSGFITGHQARGFFIQSGLPQQVLGQIWALADMNNDGKMDRKEFSIAMHLIKNKLKGLELPKVLPASLKADPVPSVGSFGPGGGGGLGMNPGMAMGMPASVGMGMGPGPGIAPPSYTSVVAPSNGYMMAPMGSATLPHGFGASAPMAGDKTRAGSINTMDQRTRSSSSTGEWAVPQQSKLKYNQTFNIHDRMKRGYLLGVEARGILMHTGLPHPILAQIWNLSDIDKDGKLTSEEFCLAMHLSDMAKSGQTLPATLPPDLLPPS 296          

Query:   83 SQWSISTEEFSQHRIQFE-HLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVP 361
             +W++  +   ++   F  H    +G++ G++A+  L  + L + IL +IW+L+D+D+DG+++  EF +AMHL      G  LP  LP ++L P
Sbjct:  202 GEWAVPQQSKLKYNQTFNIHDRMKRGYLLGVEARGILMHTGLPHPILAQIWNLSDIDKDGKLTSEEFCLAMHLSDMAKSGQTLPATLPPDLLPP 295          

Query: 1043 EKEKQRLIDLEETRLQQAVXXXXXXXXXXXXXXDRQEFLIDALAMEEEKCQMYQAKLKESLQSVESHKAHIELMRNERDELVDSTSCLFEELE-------AAKAEHSRCQ-RDRXXXXX-XXXXXXXXXPFQNDLLQLENLKQLHKQSISNLHQEIIDLQASIDLKSQNVVRNSNKLHNLEN-----AVNCHQL--------AEIRRLRSNIQSKRNEVMEILEKQTQNNDVKPIFDFHQTNGHKLPDE-----FDLESYQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNVFDQTLPDGATIKKAPNNV-----------WVEAIFPWI-------------MDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKK--LTKQDLEHAQTIDTISSDYYTALSLENSNSPTMTYDDIGRNLNDFDTDSGITDPELATPAEI--GENAAYSNYCTLAXXXXXXXXXXXXXXXLSK-AKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNE-GWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPG-DKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLLV-TPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLIMAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIRRSAGV-GRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFF 4957
            E E+QR ++ E  + Q+   +R +E+++L K+K + + L   L    +K +    K+ ++   V   K  I+ MR+ RD  +   + L  +L        A   E +R + R++ N       QE     F N  + L+ +K            +I+DLQ  ID K  ++  N+ +L +++       V+C QL         ++  LRS+      +        +   D          N   +  E       +  Y+ALY+F  R  DE++F+ GDIILV  P   N   GW+ G  +I    G FP  YV+ +D   ++      D+E +  ++ +V  +TL     I + P NV            VEAI P +                       LSF  G+ I V E++  DWW G   T           GWFP+ YV+      E + ST+ T     LN                         EY +ALY Y+ST  GDL+   G++I +      WW G I    ++G+FPS+YV+K  +  QD                  SL N  S T+   +  +N  + DT + +T  +    AE    E AA  +   L + +         +    +  +++  Y A S ++L    GQ + I   +D  W++ +L   G   + GW P          +++  T      S  +R      S PVS   Q  D    P  ++++A+YPY AQN DELSF K  ++ +++K+E  WWRG     S  G+FP NYV  P +N    D ++   Y NP                                 E++RQ +I+ELI TE+AY ED++ VH VF +P+ +S +L+++E++ IFINW D+I  + NF   L+IR+DNS N   ++ +GDIL  N P    Y+RFCS Q  A   L++  +TS +F    Q C+++ R K MP+SS+ +KPMQRITKY LI+  IL  T   HPD   ++EA+A +   C  VNEG+REKENS+RLEW+Q H+ CDGL E+L FNS TNSLG RKL++ G L+K+KSGKELVGFL NDFLL V +  ++ N   F F      +   +FKMY+KPI LN + +   S  N + + S  A        + S+   +K+     +L A S N+   W++R+V A  +++E E +  +   S +   G  GR+LVTVLEG NLK+   P  K +A+C+ S+G+Q  RT VVS +  P W+  MQF +K++  D LC++ +DK Y++P++FLGR E+ + DI +    + GPI++R+KL  V SGE+++KLDL  F
Sbjct:  605 EMERQRQLEWERQKSQELQAQRQKEQDILLKLKAKNQTLTIELGTLNDKVKELSQKICDTRVGVSGVKTTIDGMRSTRDTQLQEMAALKNKLREQNQRLLALSQEKARIEARNKINAAQDAAGQEAIKMAFDNKQITLKQMKD-----------KIVDLQQQIDSKMSDIENNNTQLEDIKTQMKNLVVDCKQLYVTFDEKKQKVIELRSDSNVSAADFATSAWGDSGWGDAPASDTAWPVNDTTVSSENEAAVVGVRKYRALYEFVARNQDEISFQPGDIILV--PPVQNAEPGWMAG--EIRGHTGWFPESYVEPIDTGAADL-----DNERTFIQQDSVEKRTL---EGIAEVPENVSDAGSLGGEAPVVEAIIPTLGLGTFCSIQVTTLFPYRPTMEQHLSFEKGETINVSEQQD-DWWYGSANTGNN--------GWFPKSYVK------EIITSTKDTAA-DGLN-------------------------EYYVALYRYDSTETGDLSFNQGEVILVTKKEGEWWTGCI--GNKSGIFPSNYVEKYNVPNQDA-----------------SLSNVQSTTVVATEETKN--EIDTMATVTAQQAEKTAEQLEDERAAAEDRAELPDFTAMAAQQYYKRGRKPEIVQVIAPYQATSSEQLDLQRGQLIMIRKKTDSGWWEGELQARGKKRQVGWFP--------ATYVKPLT------SSSNR------STPVSHGYQ--DSPTDPNIERVMALYPYQAQNEDELSFEKGDVISVLAKEEASWWRGELNGVS--GVFPSNYV-SPMSNELMVDIVM---YHNPM--------------------------------ERKRQEHIKELIVTEQAYIEDMRLVHEVFEKPLIESLVLSVDEIEKIFINWRDIIACNDNFLRTLRIRRDNSYNGI-VRMIGDILCENIPRMSAYIRFCSCQISAATYLQRLTETSPEFVRVAQACQQDPRTKGMPLSSFLIKPMQRITKYPLIINKILDYTPIDHPDRQYLQEALAKSEEFCTQVNEGVREKENSDRLEWLQSHIICDGLEEQLIFNSLTNSLGPRKLLHFGILHKSKSGKELVGFLTNDFLLFVQSIKFSLNCQQFSF----ERNEHQKFKMYRKPIFLNELSLFGESDGNNSLNGSDIAD-------NSSKTLRLKDQKKSIILLAPSANECSLWLKRIVEARRRFLENEKNCLQRQRSKQAQFGACGRILVTVLEGFNLKA---PSGKCNAFCKVSMGSQEERTSVVSGSDCPLWDASMQFQVKDLFEDTLCITVFDKGYYSPDEFLGRAEIRVADIIRDSKNSCGPIQKRIKLHEVESGEVVLKLDLRLF 1809          

Query:  536 SPQT-DWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSMVTISNNNKSLPNSHTEH 883
            SPQ+ +W +    + +Y   FN  DR + GFLSG +A+ +++QS L   ILAQIW L+D+DSDG+L  EEF +AM+L + A+ G  +P+ LP  L+PP+      ++ +L  + TE+
Sbjct:  387 SPQSVEWAVPHQTKLKYTQLFNTWDRTRSGFLSGPQARNIMVQSQLPQPILAQIWALADMDSDGRLGSEEFVLAMHLCDIAKVGENIPTTLPPELIPPTFRRQRQSSLTLSQNATEN 503          

Query:   89 WSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLP 343
            W I   E  +++ QF+ L P+ G ++G QAK +L +S+L   ILG+IW+L+D D DG+M ++EFSIA  LI  KL G E+P VLP
Sbjct:   12 WVIQPRERLRYQEQFDSLKPINGIVTGEQAKGFLLRSQLQPAILGQIWALSDTDADGKMDINEFSIACKLINLKLRGFEIPKVLP 96          

Query:  533 TSPQTDWVIMQAVRPRYRLQFNQQDRNKK---GFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLV 820
            ++PQT  +    ++PR RL++ +Q  + K   G ++G++AK  LL+S L  +IL QIW LSD D+DGK+   EF +A  L+     G  +P  LP  LV
Sbjct:    2 STPQTPGMDPWVIQPRERLRYQEQFDSLKPINGIVTGEQAKGFLLRSQLQPAILGQIWALSDTDADGKMDINEFSIACKLINLKLRGFEIPKVLPPVLV 100          

Query:  155 GFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPP 364
            GF+SG QA+  + +S+L   IL +IW+LAD+D DGR+   EF +AMHL      G  +P  LP E L+PP
Sbjct:  416 GFLSGPQARNIMVQSQLPQPILAQIWALADMDSDGRLGSEEFVLAMHLCDIAKVGENIPTTLPPE-LIPP 484          

Query: 1586 EIRRLRSNIQSKRNEVMEILEK--QTQNNDVKPIFDFHQTNGHKLP------DEFDLESYQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNVFDQTLPDG---ATIKKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVK-------KLTKQD------------LEHAQTIDTISSDYYTAL-SLENSNSPTMTY---DDIGRNLNDFDTDSGITDPELATPAEIGENAAY--SNYCTLAXXXXXXXXXXXXXXXLSK----AKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNE-GWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLL--VTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLI-MAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIR--RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFF 4957
            EI + + +    + E+ E L K  Q   + +KP      +N  K P      ++  +  Y+ALY F  R  DE+T + GDI++V + S    P GWL G LK     G FP  Y +K+ P       + P  E +   + +V + T+  G   +T      N W +    W  +  ++                E  + D W  +        G                       L   S    + +  ++ + + G               G    ALYP+ +     L     DII +++    WW G ++G +  G FP  YVK       K T  D            +    T  T+S + Y A+ + E+S    +T+   D I     D D  +G           +G+ +    SNY  L               SL K    A+++ +Y+A   ++L+  PGQ + I   +   W++ +L   G   + GW P          +++      + + G  +  T    LP S     +        ++I MY Y+AQN DEL+F K  I+ +++K++P+WW+G       +GLFP NYV+      + D         +PS +              W  D  ++   +LT  E++RQ YI ELI TE+ Y  DLQ V  +F +P+ +S LLT +E+  IF+NW +LI  +     AL++RK  SG K P++ +GDIL +  P+   Y+RFCS Q    AL+++K     +FKEF ++   + RCK MP+SS+ LKPMQR+T+Y LI++NI++NT + HPD   ++ A+  A  LC  VNEG+REKENS+RLEWIQ HVQC+GL+E+L FNS TN LG RK ++SG LYKAKS KEL GFLFNDFLLL  +     ++G   VF    S    +Q+KMYK PI LN VL+ +   PS                      IF I      + L+A S+N+R  WV+++ AAS  YIETE   RE +  +R  R+ G+GRL+V ++EG  LK   +   K++ YCE ++G+Q   TK +  T NPKWN + QF IK++E DVLC++ ++++ F+P+DFLGRTE+ + DIK+ +  +KGP+ + L L  V +GE++V+LDL  F
Sbjct:   38 EITKKKESEDKGKQEMQEKLSKLFQPHQDPIKPAVQAPWSNAEKAPLTISAQEDVKIVYYRALYPFESRSHDEITIQPGDIVMV-DESQTGEP-GWLGGELKGKT--GWFPANYAEKI-PENEVPASVKPAVEAAAAPKVSVHETTMSLGTPASTECTTTANNWADFSSTWPTNTSEKP---------------ETDNWDAWAAQPSLTVPSAGQ----------------------LRQRSAFTPATVTGSSPSPVLG---------QGEKVEGLQAQALYPWRAKKDNHLNFNKNDIITVLEQQDMWWFGEVQGQK--GWFPKSYVKLISGPIRKSTSMDSGSSESPASLKRVASPATKATMSGEEYIAMYTYESSEQGDLTFQQGDMILVTKKDGDWWTGT----------LGDKSGVFPSNYVRL--KDSEAPGAAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFP--------ANYVK------LLSPGTSK--TTPTELPKSTALPSVC-------QVIGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGE--VNGQVGLFPSNYVK-----LTTD--------MDPSQQ--------------WCAD--LHLLDMLTPTERKRQGYIHELIVTEENYVNDLQLVTEIFQKPLMESELLTEKEVAMIFVNWKELIMCNIKLLKALRVRKKMSGEKMPVKMIGDILTAQLPHMQPYIRFCSCQLNGAALIQQKTDEVPEFKEFVKRLAMDPRCKGMPLSSFLLKPMQRVTRYPLIIKNIIENTPENHPDHSHLKHALEKAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQIIKPLGSSGTDKVF----SPKSNLQYKMYKTPIFLNEVLVKLPTDPSGDE------------------PIFHISHIDRVYTLRAESINERTAWVQKIKAASELYIETEKKKREKAYLVRSQRATGIGRLMVNIVEGIELKPCRS-HGKSNPYCEVTMGSQCHITKTIQDTLNPKWNSNCQFFIKDLEQDVLCITVFERDQFSPDDFLGRTEIRVADIKKDQ-GSKGPVTKCLLLHEVPTGEIVVRLDLQLF 1064          

Query: 1043 EKEKQRLIDLEETRLQQAVXXXXXXXXXXXXXXDRQEFLIDALAMEEEKCQMYQAKLKESLQSVESHKAHIELMRNERDELVDSTSCLFEELE-------AAKAEHSRCQRDRXXXXXXXXXXXXXXPFQNDLLQLENLKQLHKQSISNLHQEIIDLQASIDLKSQNVVRNSNKLHNLENAVNCHQLAEIRRLRSNIQSKRNEVMEILEKQTQ-----------------------NNDVKPIFDFHQTNGHKLPDEFDLESYQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNVFDQTLPDGATIKKAPNNV-----------WVEAIFPWI-------MDAEDETP------DQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQTIDTISSDYYTALSLENSNSPTMTYDDIGRNLNDFDTDSGITDPELATPAEIGENAAYSNYCTLAXXXXXXXXXXXXXXXLSKAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNE-GWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPG-DKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLLVTP-SYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLIMAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETE-NSVREISMSIRRSAGVGRLLVTVLEGANLKSSST----PE------------------TKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFF 4957
            E E+QR ++ E  + Q+   +R +E+++L K+K + + L   L    +K +    K+ ++   V   K  I+ MR+ RD  +   + L  +L        A   E +R +        +     ++     D  Q+  LKQ+  +        I DLQ  ID K  ++  N+ +L  ++  +    +A+ ++L  N   K+ +V+E+    +                        ++   P+ D    N     D   +  Y+ALY+F  R  DE++F+ GDII V  P   N   GW+ G  +I    G FP  YV   +PV +  + L  D+E +  ++ +V  +TL +   I + P NV            VEAI P +       ++A    P        LSF  G+ I V E+++ DWW G      +        GWFP+ YV+ +  SN+ + +         LN                         EY +ALY Y+ST  GDL+   G++I ++     WW G +    + G+FPS+YV+K    +       +T S++            P      + +     + +    +          + A   ++  +A    G              +++  Y A S ++L    GQ + I   +D  W++ +L   G   + GW P          +++  T      S  +R      S PVS   Q  D    P  ++++A+YPY AQN DELSF K  ++ +++K+E  WWRG     S  G+FP NYV    +  + D                    T+   P+                 EK+RQ +I+ELI TE+AY ED++ VH VF +P+ +S +++++E++ IFINW D+I  + NF   L+IR+DNS N   ++ +GDIL  N P    Y+RFCS Q  A   L++  +T  +F    Q C+++ R K MP+SS+ +KPMQRITKY LI+  IL+ T   HPD   ++EA+A +   C  VNEG+REKENS+RLEW+Q HV CDGL E+L FNS TNSLG RKL++ G L+K+KSGKELVGFL NDFLL V P  ++ N   F F      +   +FKMY+KPI LN + ++  +  N + S S  A        + S+I  +K+     +L A S N+   W +R+V A  +++E E N ++       +    GR+LVTVLEG NLK+ S     PE                   K + +C+ S+G+Q  RT VVS    P W+  MQF +K++  D LC++ +DK Y++P++FLGR E+ + DI +    + GPI++R+KL  V+SG++I+KLDL  F
Sbjct:  601 EMERQRQLEWERQKSQELQAQRQKEQDVLLKLKAKNQTLTIELGTLNDKVKELSQKICDTRVGVSGVKTTIDGMRSTRDAQLQEMAALKNKLREQNQRLLALSQEKARIEAKNKLNAAQDAAGQEAVKMAFDNKQI-TLKQMKDK--------IADLQQQIDSKMSDIENNNAQLEEIKTQIK-DLIADCKQLYINFDDKKKKVLELRASGSSVSAADFATSAWGDSAWSNAPSIASDAAWPVDDTTTVNSTNEADVVGVRKYRALYEFVARNQDEISFQPGDIISV--PPVQNAEPGWMAG--EIRGHTGWFPESYV---EPVDTGTISL--DNERTFIQQDSVEKRTLEE---IAEVPENVSDAGSLGGEAPIVEAIIPTLGLGTSCHIEATALFPYRPTMEQHLSFEKGETIYVSEQQA-DWWYGSTSNENK--------GWFPKSYVKEIITSNKDVAT-------DGLN-------------------------EYYVALYRYDSTEAGDLSFNQGEVILVIKKEGDWWTGCV--GDKTGIFPSNYVEKCDAPNQSSVTAPETKSTEDVI---------PITAASQVEKTAEQLEDERAAAE----------DRAELPDFTAMAAQQRGGRKPEI-------VQVIAPYQATSAEQLDLQRGQLIMIRKKTDSGWWEGELQARGKRRQVGWFP--------ATYVKPLT------SSSNR------STPVSHGYQ--DSPTDPNIERVMALYPYQAQNEDELSFEKGDVISVLAKEETAWWRGELNGVS--GVFPSNYVSPMSSELTID--------------------TICHNPM-----------------EKKRQEHIKELIVTEQAYIEDMRLVHEVFEKPLIESLVMSVDEIEKIFINWRDIIACNDNFLRTLRIRRDNSYNGV-VRMIGDILCENIPRMSAYIRFCSCQISAAMYLQRLTETLPEFVRVAQTCQQDPRTKGMPLSSFLIKPMQRITKYPLIIGKILEYTPIDHPDRQYLQEALAKSEEFCIQVNEGVREKENSDRLEWLQTHVICDGLEEQLVFNSLTNSLGPRKLLHYGILHKSKSGKELVGFLTNDFLLFVQPMKFSLNCQQFSF----ERNEHQKFKMYRKPIFLNELSLLGENDGNSSLSGSDAAD-------NSSKILRLKDQKKPIILSASSANECSLWSKRIVEARRKFLENERNRLQRQRSKQAQFRACGRILVTVLEGFNLKAPSVRRRPPEGRLRLVVVEAEDLVISKKGKCNTFCKVSMGSQEERTGVVSGNDCPWWDASMQFQVKDLLEDTLCITVFDKGYYSPDEFLGRAEIRVADIMRDSKDSCGPIQKRIKLHEVDSGDVILKLDLRLF 1821          

Query:  536 SPQT-DWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSMVTISNNNKSLPNSHTEH 883
            SPQ+ +W +    + +Y   FN  DR + GFLSG +A+ +++QS L   ILA+IW LSD+DSDG+L  EEF +AM+L + A+AG  +P+ LP  L+PP+      ++ +L  + TE+
Sbjct:  383 SPQSIEWAVPHQTKLKYTQLFNTWDRTRSGFLSGPQARNIMVQSQLPQPILARIWALSDMDSDGRLGSEEFVLAMHLCDIAKAGETIPTTLPLELIPPTFRRQRQSSLTLSQNATEN 499          

Query:   89 WSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPPDSFPFSDLGANEIFSSKAAPSYNEV 439
            W I   E  +++ QF+ L P+ G ++G QAK +L +S+L   ILG+IW+L+D D DG+M ++EFSIA  LI  KL G E+P VLP  ++    SFP  D  AN +  +  + + N +
Sbjct:   12 WVIQPRERMKYQEQFDSLKPLNGVVTGEQAKGFLLRSQLPPPILGQIWALSDTDSDGKMDINEFSIACKLINLKLRGFEIPKVLPPILIQSLKSFPTGD--ANLVGLTNGSTAQNNI 126          

Query:  536 SPQTDWVIMQAVRPRYRLQFNQQDRNKK---GFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLV 820
            +PQT  +    ++PR R+++ +Q  + K   G ++G++AK  LL+S L   IL QIW LSD DSDGK+   EF +A  L+     G  +P  LP  L+
Sbjct:    3 TPQTPGIDPWVIQPRERMKYQEQFDSLKPLNGVVTGEQAKGFLLRSQLPPPILGQIWALSDTDSDGKMDINEFSIACKLINLKLRGFEIPKVLPPILI 100          

Query:  155 GFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPP 364
            GF+SG QA+  + +S+L   IL +IW+L+D+D DGR+   EF +AMHL      G  +P  LP E L+PP
Sbjct:  412 GFLSGPQARNIMVQSQLPQPILARIWALSDMDSDGRLGSEEFVLAMHLCDIAKAGETIPTTLPLE-LIPP 480          

Query: 1424 QLENLKQLHKQSISNLHQEIIDLQASIDLKSQNVVRNSNKLHNLENAVNCHQLAEIRRLRSNIQSKRNEVMEILE-----KQTQNNDVKPIFDFHQ----------TNGHKLP------DEFDLESYQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNVFDQTLPDGATIKK---APNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQTIDTISSD---------------------YYTALSLENSNSPTMTY---DDIGRNLNDFDTDSGITDPELATPAEIGENAAY--SNYCTLAXXXXXXXXXXXXXXXLSK----AKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNE-GWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLL--VTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLI-MAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIR--RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFF 4957
            QL+  K L  + +    QE   ++     ++Q  +++ +K   LE      +    ++++ + + KR E+ +  E     KQ     +  +F  HQ          +N  K P      ++  +  Y+ALY F  R  DE+T + GDI++V + S    P GWL G LK     G FP  Y +K+ P         P SE S   + +V + + P GA       A  N W +    W  +  ++                E  + D W  +        G                       L   S    + +  ++ + + G               G    ALYP+ +     L     D+I +++    WW G ++G  + G FP  YVK L    +  + ++D+ SS+                     Y    + E+S    +T+   D I     D D  +G           +G+ +    SNY  L               SL K    A+++ +Y+A   ++L+  PGQ + I   +   W++ +L   G   + GW P   +        +    +L  A+    C                        ++I MY YSAQN DEL+F K  I+ ++++++P+WW+G       +GLFP NYV+      + D         +PS +              W  D  ++   +LT  E++RQ YI ELI TE+ Y  DLQ V  +F +P+ +S L+T +E+  IF+NW +LI  +     AL++RK  SG K P++ +GDIL +  P+   Y+RFCS Q    AL+++K     +FKEF ++   + RCK MP+SS+ LKPMQR+T+Y LI++NI++NT + HPD   ++ A+  A  LC  VNEG+REKENS+RLEWIQ HVQC+GL+E+L FNS TN LG RK ++SG LYKAKS KEL GFLFNDFLLL  +     ++G   VF    S    +Q+KMYK PI LN VL+ +   PS                      IF I      + L+A S+N+R  WV+++ AAS  YIETE   RE +  +R  R+ G+GRL+V V+EG  LK   +   K++ YCE ++G+Q   TK +  T NPKWN + QF IK++E DVLC++ ++++ F+P+DFLGRTE+ + DIK+ +  +KGP+ + L L  V +GE++V+LDL  F
Sbjct:  605 QLQKQKSLEAERLKQKEQERKTVELEKQKEAQRRIQDRDK-PRLERGQPEEEPQWQKKIQEDDKQKREELPKKKESEDKGKQEMQEKLSKLFQPHQEPNKPGQAPWSNAEKAPLTISAQEDVKIVYYRALYPFESRSHDEITIQPGDIVMV-DESQTGEP-GWLGGELKGKT--GWFPANYAEKI-PDSEVPASAKPASEPSAAPKVSVQETSTPLGAPAPPEGPAVANNWADFSSTWPTNTSEKP---------------ESDNWDAWAAQPSLTVPSAGQ----------------------LRQRSAFTPATVTGSSPSPVLG---------QGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDMWWFGEVQG--QKGWFPKSYVK-LISGPIRKSTSMDSGSSESPASLKRVASPAAKAAMSGEEYIAMYTYESSEQGDLTFQQGDLILVTKKDGDWWTGT----------LGDKSGVFPSNYVRL--KDSEAPGAAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLLSPGTSKSTPTELPKAAAPSVC------------------------QVIGMYDYSAQNDDELAFNKGQIINVLNREDPDWWKGE--VNGHVGLFPSNYVK-----LTTDT--------DPSQQ--------------WCAD--LHLLDMLTPTERKRQGYIHELIVTEENYVNDLQLVTEIFQKPLMESELVTEKEVAMIFVNWKELIMCNIKLLKALRVRKKMSGEKMPVKMIGDILTAQLPHMQPYIRFCSCQLNGAALIQQKTDEVPEFKEFVKRLAMDPRCKGMPLSSFLLKPMQRVTRYPLIIKNIIENTPENHPDHSHLKHALEKAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQIIKPLGSSGTDKVF----SPKSNLQYKMYKTPIFLNEVLVKLPTDPSG------------------DEPIFHISHIDRVYTLRAESINERTAWVQKIKAASELYIETEKKKREKAYLVRSQRATGIGRLMVNVVEGIELKPCRS-HGKSNPYCEVTMGSQCHITKTIQDTLNPKWNSNCQFFIKDLEQDVLCITVFERDQFSPDDFLGRTEIRVADIKKDQ-GSKGPVTKCLLLHEVPTGEIVVRLDLQLF 1696          

Query:   74 GNQSQWSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPPDSFPFS-DLGANEIFSSKAAPSYNEVMAKDKADRQSFREKPPIPQDIQSTFPPL--------------------PK-----RTSPQT---------------------DWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSMVTI 841
            GN   W+I+ EE ++H  QF  L P  GFI+G QA+ +  +S L   +L +IW+LAD++ DGRM   EFSIAM LIK KL+G +LP  LP  M  PP + P +   G   I +    PS   V     A        PP+   + +  PPL                    PK     R+ P                       +W + Q+ R +YR  F   D+   G L+G +A+ +L+QS L  + LA IWNLSDID DGKLT EEF +AM+L++ A +G+ LP  LP   +PPS   +
Sbjct:   10 GNLDIWAITVEERAKHDQQFHSLKPTAGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDPLEFSIAMKLIKLKLQGYQLPATLPPVMKQPPLALPGAPGFGLGGIAN---MPSLTTVAPVPMASIPVVGMSPPLVSSVPAAVPPLANGAPAVIQPLPAFAHPATLPKSSSFSRSGPGAQLNAKLQKAQSFDVASAPAVAEWAVPQSSRLKYRQLFTSHDKTMSGHLTGPQARTILMQSSLPQAQLATIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPALPPEYIPPSFRRV 309          

Query: 2039 VWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGD--WWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETL------------------LST--------ESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQTIDTISSDYYTALSLENSNSPTM---TYDDIGRNLNDFDTDSGIT----DPELATPAEIGENAAY-SNYCTLAXXXXXXXXXXXXXXXLSK----AKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNE-GWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLL--VTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLI-MAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIR--RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFF 4957
            V+  A++P+    E  + D+++   G  + V E ++G+  W  GE+   T         GWFP  Y + +  S   L                  LS          S    + L+ ++ + + G               G    ALYP+ +     L     D+I +++    WW G ++G R  G FP  YVK ++      A   +      Y    + ++ +P +   TY+   +    F     IT    + +  T    G+   + SNY  +               SL K    A+++  Y+A   ++L+  PGQ + I   +   W++ +L   G   + GW P                N +   S    C                        ++I MY Y+AQN DEL F K  I+ ++S+++P+WW+G       +GLFP NYV+      + D         +PS +              W  D  ++   +LT  E++RQ YI ELI TE+ Y  DLQ V   F +P+ +S LLT +E+  IF+NW +LI  +     AL++RK  SG + P++ +GDIL +  P+   Y+RFCS Q     L+++K      FK+F ++   + RCK MP+SS+ LKPMQR+T+Y LI++NIL+NT + HPD   + +A+  A  LC  VNEG+REKENS+RLEWIQ HVQC+GL+E+L FNS TN LG RK ++SG LYKAKS KEL GFLFNDFLLL  V     ++    VF    S+   +Q++MYK PI LN VL+ +   PS                      IF I      + ++A S+N+R  WV+++ AAS  +IETE   RE +  +R  R+ G+GRL+V ++EG  LK   +   K++ YCE ++G+Q   TK +  T NPKWN + QF IK++E DVLC++ ++++ F+P+DFLGRTE+ L DIK+ +  +KGPI +RL L  V +GE++V+LDL  F
Sbjct:  656 VYYRALYPF----EARSHDEITIQPGDIVMVDESQTGEPGWLGGEIKGKT---------GWFPANYAEKIPESEVPLNLRASATSGSPAQPPQPSLSVPSGGQGRQRSAFTPATLSGSSPSPVLG---------QGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDMWWFGEVQGQR--GWFPKSYVKLISGNKSISALAHEHSYMQIYRLCMVNSTATPYIAMYTYESNEQGDLTFQQGDVITVLKKEGDWWTGTVSGKTGVFPSNY--VKPKDSDGLGPAGKTGSLGKKPEIAQVIAPYTATGAEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFP---------------ANYVKLLSPSTMC------------------------QVIGMYDYAAQNDDELPFGKGQIINVLSREDPDWWKGE--LNGSVGLFPSNYVK-----LTTDT--------DPSQQ--------------WCAD--LHLLDMLTPMERKRQGYIHELIITEENYVNDLQLVTETFQKPLLESELLTEKEVAMIFVNWKELIMCNIKLLKALRVRKKMSGERMPVKMIGDILTAQLPHMQPYIRFCSCQLNGATLIQQKTDEVPDFKDFVKRLAMDPRCKGMPLSSFLLKPMQRVTRYPLIIKNILENTPESHPDHSHLRQALEKAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQVIKPLGSSATDKVF----SAKSHLQYRMYKTPIFLNEVLVKLPTDPSGDE------------------PIFHISHIDRVYTIRAESINERTAWVQKIKAASELFIETEKKKREKAYLVRSQRATGIGRLMVNIVEGIELKPCRS-HGKSNPYCEVTMGSQCHITKTLQDTLNPKWNSNCQFFIKDLEQDVLCVTVFERDQFSPDDFLGRTEIRLADIKKDQ-GSKGPITKRLLLHEVPTGEIVVRLDLQLF 1554          

Query: 1664 NDVKPIFDFHQTNGHKLPDEFDLESYQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNVFDQTLPDGATIKK------------APNNVW----------VEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPV--DYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQTIDTISSD--------YYTALSLENSNSPTMTYDDIGRNLNDFDTDSGITDPELATPAEIGENAAY-SNYCTLAXXXXXXXXXXXXXXXLSKAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTN 2956
             D  P+  F+Q       D+  +  Y+ALY F  R  DE+T + GDI++V + S    P GWL G +K     G FP  Y +K+ P     L L   + + +  +      ++P G   ++            +P+ V            +A++PW    ++     L+FN    I V+E++   WW GE+             GWFP+ YV+ +  + S   L    S M+   L    S      P                 +A+Y YES   GDLT + GD+I ++     WW G + G  + G+FPS+YVK      L  A    ++            YTA   E      +T       L       G  + EL    +  +   + +NY  L            + +++ +   +  Y+A + DEL    GQ +N++   D DW+K +L  NGS  
Sbjct:  640 TDKVPMSGFNQ-------DKVRVVYYRALYPFEARSHDEITIQPGDIVMV-DESQTGEP-GWLGGEIKGKT--GWFPANYAEKI-PESEVPLNLRASATSGSPAQPPQPSLSVPSGGQGRQRSAFTPATLSGSSPSPVLGQGEKVEGLQAQALYPWRAKKDN----HLNFNKNDVITVLEQQDM-WWFGEVQGQR---------GWFPKSYVKLISGNKSISALAHEHSYMQIYRLCMVNST---ATPY----------------IAMYTYESNEQGDLTFQQGDVITVLKKEGDWWTGTVSG--KTGVFPSNYVKPKDSDGLGPAGKTGSLGKKPEIAQVIAPYTATGAEQ-----LTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKL-----------LSPSTMCQVIGMYDYAAQNDDELPFGKGQIINVLSREDPDWWKGEL--NGSVG 1038          

Query:  482 PPIPQDIQSTFPPLPKRTSPQTDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAG 784
            PP+     +   P+P       DW + Q+ R +YR  FN  D+   G L+G +A+ +L+QS L  + LA IWNLSDID DGKLT EEF +AM+L++ A +G
Sbjct:  198 PPLSFSYSAPAAPVP------IDWAVPQSSRLKYRQLFNSHDKMMSGHLTGPQARTILMQSSLPQAQLATIWNLSDIDQDGKLTAEEFILAMHLIDMAMSG 292          

Query:  146 PVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEG 319
            P   F +G QAK +  +S L   +L +IW+LAD++ DG+M +HEFSIAM LIK KL+G
Sbjct:   34 PNHSFSTGDQAKNFFLQSGLPAPVLAQIWALADLNNDGKMDMHEFSIAMKLIKLKLQG 91          

Query:  623 FLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAG 784
            F +GD+AK   LQSGL   +LAQIW L+D+++DGK+   EF +AM L++    G
Sbjct:   38 FSTGDQAKNFFLQSGLPAPVLAQIWALADLNNDGKMDMHEFSIAMKLIKLKLQG 91          

Query:   89 WSISTEEFSQHRIQF-EHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEG 319
            W++      ++R  F  H   + G ++G QA+  L +S L    L  IW+L+D+DQDG+++  EF +AMHLI   + G
Sbjct:  215 WAVPQSSRLKYRQLFNSHDKMMSGHLTGPQARTILMQSSLPQAQLATIWNLSDIDQDGKLTAEEFILAMHLIDMAMSG 292          

Query: 3140 MYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLLVTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLI-MAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIR--RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFF 4957
            MY Y A + DE+SF K  ++ + +KD+ +WW+G      + GLFP NY++           + ++S  +PS +              W  D +++ +++ +E E++RQ YI ELI TE  Y +DL+ V  VFY+P+ +S  LT  E+  IF+NW +LI  +     AL++RK  +G + P+Q +GDIL S   +   Y+RFCS Q  A ALL++K   S  FK F ++   N RCK MP+SS+ LKPMQRIT+Y L++ NIL+NT   H D  ++ EA+  A  LC  VNEG+REKENS+RLEWIQ+HVQC+G+ E L FNS TN LG RKL++SG ++K KS KEL  FLF+DFLLL   +Y    +        S      +KMYK P+ LN VL+ M   PS                  S   IF I      + LKA S+++R  WV+R+ AAS  +IETE   RE +   R  +++G+GRLLVTV E   LK    P  K++ YCE S+G Q   ++  + T NPKWN + QF IK++  DVLC++ ++++ F+P+DFLGRTEV +  IK+ +   KGP+ RRL L  V +GE+ V+LDL  +
Sbjct:    1 MYDYKAASEDEMSFLKGQLINVFNKDDSDWWKGE--LNGVTGLFPTNYIK-----------MTTES--DPSQQ--------------WCAD-LLSLDSMSSE-ERKRQGYIHELIHTEHTYLQDLELVLEVFYKPMTESGRLTEAEMGVIFVNWRELIMCNTKLLKALRVRKKTAGERMPVQMIGDILSSELAHMQAYIRFCSCQLNAAALLQQKTDASPDFKLFLKKIATNYRCKGMPLSSFLLKPMQRITRYPLLIRNILENTPAGHADQANLREALDRAEELCSQVNEGVREKENSDRLEWIQNHVQCEGVIEHLVFNSLTNCLGPRKLLHSGRVWKTKSSKELWAFLFSDFLLL---TYTAKQFSSSTDKLFSPKSNTMYKMYKTPVFLNEVLVKMPSDPS------------------SDDPIFHISHIDRVYTLKADSISERTTWVQRIKAASEHFIETEKLKREKAYQARSQKTSGIGRLLVTVQEAVELKPCK-PNGKSNPYCELSMGAQCYTSRPQNDTVNPKWNFNCQFFIKDLYQDVLCITIFERDQFSPDDFLGRTEVPVATIKKDQ-EGKGPLTRRLLLHEVPTGEVRVRLDLQLY 555          

Query: 3437 LTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLL--VTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLI-MAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIR--RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFF 4957
            ++  EK+RQ YI ELIETE+ Y EDLQ V  VF++P+ +S  LT  E+  IF+NW +LI  +     AL++RK   G K P+Q VGDIL +   +   Y+RFCS Q  A ALL++K      FK+F ++   + RCK MP+SS+ LKPMQRIT+Y L ++NIL++T D H D   + EA+  A  LC  VNEG+REKENS+RLEWIQ+HVQC+G+ E L FNS TN LG RKL++SG L+K KS KEL  FLF DFLL       + ++G   +F  ++S+    Q+++YK P+ LN VL+ M   PS                  S   +F I      + LK  ++N+R  WV+++ AAS ++IETE   RE +   R  +++G+GRLLVT+ E   LKSS  P  K++ YCE ++G Q   ++ ++ T NPKWN   QF IK++  DVLC++ Y++E FAP+DFLGRTEV +  IK+ +L NKGP  RRL L  V +GE+ V+LDL  F
Sbjct:   22 MSPQEKKRQGYIHELIETEERYMEDLQLVLEVFHKPMSESGRLTEAEMNMIFVNWKELIMCNTKLVKALRVRKKTGGEKMPVQMVGDILAAELSHMQAYIRFCSCQLNAAALLQQKTDQEPDFKDFLKKIATDYRCKGMPLSSFLLKPMQRITRYPLHIKNILESTPDSHVDHSQLREALEKAEELCSQVNEGVREKENSDRLEWIQNHVQCEGITESLVFNSLTNCLGPRKLLHSGKLFKTKSNKELYAFLFTDFLLFTQAVKQFTSSGADKLFSPKSST----QYRIYKSPVFLNEVLVKMPSDPS------------------SDEPVFHISHIDRVYTLKTENINERTAWVQKIKAASEEFIETEKKKREKAYQARSMKASGIGRLLVTIQEATELKSSK-PSGKSNPYCEVTMGAQCYTSRTLNDTVNPKWNFQCQFHIKDLYQDVLCITIYEREQFAPDDFLGRTEVPVATIKK-ELENKGPATRRLLLHEVPTGEVWVRLDLQLF 509          

Query: 3437 LTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLLVTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLI-MAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIR--RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFF 4957
            ++ +E++RQ YI ELI TE  Y +DL+ V  VFY+P+ +S  LT  E+  IF+NW +LI  +     AL++RK  +G + P+Q +GDIL S   +   Y+RFCS Q  A ALL++K   S  FK F ++   N RCK MP+SS+ LKPMQRIT+Y L++ NIL+NT   H D  ++ EA+  A  LC  VNEG+REKENS+RLEWIQ+HVQC+G+ E L FNS TN LG RKL++SG ++K KS KEL  FLF+DFLLL   +Y    +        S      +KMYK P+ LN VL+ M   PS                  S   IF I      + LKA S+++R  WV+R+ AAS  +IETE   RE +   R  +++G+GRLLVTV E   LK    P  K++ YCE S+G Q   ++  + T NPKWN + QF IK++  DVLC++ ++++ F+P+DFLGRTEV +  IK+ +   KGP+ RRL L  V +GE+ V+LDL  +
Sbjct:   82 MSSEERKRQGYIHELIHTEHTYLQDLELVLEVFYKPMTESGRLTEAEMGVIFVNWRELIMCNTKLLKALRVRKKTAGERMPVQMIGDILSSELAHMQAYIRFCSCQLNAAALLQQKTDASPDFKLFLKKIATNYRCKGMPLSSFLLKPMQRITRYPLLIRNILENTPAGHADQANLREALDRAEELCSQVNEGVREKENSDRLEWIQNHVQCEGVIEHLVFNSLTNCLGPRKLLHSGRVWKTKSSKELWAFLFSDFLLL---TYTAKQFSSSTDKLFSPKSNTMYKMYKTPVFLNEVLVKMPSDPS------------------SDDPIFHISHIDRVYTLKADSISERTTWVQRIKAASEHFIETEKLKREKAYQARSQKTSGIGRLLVTVQEAVELKPCK-PNGKSNPYCELSMGAQCYTSRPQNDTVNPKWNFNCQFFIKDLYQDVLCITIFERDQFSPDDFLGRTEVPVATIKKDQ-EGKGPLTRRLLLHEVPTGEVRVRLDLQLY 568          

Query:   44 FKNNTISIMLGNQS----QWSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPPDSFPFSDLGANEIFSSKAAPSYNEVMAKDKADRQSFREKPPIPQ--DIQSTFPPLPKRT--SPQ--TDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQ-ARAGRALPSKLPETLVPPSMVTISNNNKSL 862
            FK+ +   + G  S     W++  EE S+    FE L PV G +SG + K  L  SKL   +LGK+W L+D+D+DG +   EF++AMHL+ + LE   +P+VLP   L+PP     S   A  +         +    KD     S R  P       + S     PK T  S Q   +WV+  A R RY   F + D +  GF+SG E K + + SGL  +ILA IW L+D    GKLT E+F +AM+ ++Q    G   P  L   ++PPS     +++ S+
Sbjct:  133 FKDQSSPSLTGAPSSDCGHWAVRPEEKSKFDGIFESLAPVNGLLSGEKVKPVLMNSKLPVDVLGKVWDLSDIDKDGHLDKDEFAVAMHLVYRALEKEPVPSVLPSS-LIPPSKRKKS---AGSLPGMAPVLPGSPPPPKD-----SLRSTPSHGSMNSLNSAGSLSPKHTIKSSQHSVNWVVPAADRQRYDDIFLKTDADLDGFVSGQEVKDIFMHSGLPQNILAHIWALADTRQMGKLTREQFALAMHFIQQKVSKGLDPPQALTPEMIPPSERGTPDSSSSV 407          

Query:   53 NTISIMLGNQSQ-----WSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPPDSFPFSDL-------------GANEIF---------SSKAAPSYNEVMAKDKADRQSFREKPPIPQDIQSTFPPLPKRTSPQTDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQ-ARAGRALPSKLPETLVPPSMVTISNNNKS 859
            +T S  LG+ +Q     W +  +E ++    F+ L P  G +SG + K  L  S L  ++LGK+W L+D+D+DG +   EF++AMHL+ + L+   +P+V+P + LVPP   P +               GA  +          S ++ PS+  V +       S + +P + Q   +T             WV+  A + +Y   F + D +  G +SG E K + +QSGL  ++LAQIW L+D    GKLT ++F + MYL+ Q    G   P  L   ++PPS   +S  + +
Sbjct:  105 DTGSPQLGSSAQNPEAFWVVKPDEKTKFDGIFDSLGPANGLLSGEKVKPVLINSNLPMEVLGKVWDLSDIDKDGHLDRDEFAVAMHLVYRALDKEPVPSVIPPK-LVPPAKRPSAAAAGGGGVKHPGMLPGAVPVLPSSPPPPRDSLRSTPSHGSVSSLASGGSLSPKLQPRLLQQTHTT-------------WVVTPADKIKYDEIFLKTDLDMDGLVSGLEVKDIFMQSGLPQAVLAQIWALADTRQQGKLTQDQFAL-MYLITQKVSKGVDPPVTLNADMMPPSERGVSTTDGA 386          

Query:  155 GFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPPDSFPFSDLGANEIFSSKAAPSYNEVMAKDKADRQSFREKPPIPQDIQSTFPPLPKRTSPQTDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPS 829
            G +   +A  +L KS LS+  LGKIW LAD D+ G +    F +A+ L+     G E+       ++ PP    F D G+ ++ SS                                         +P+  WV+    + ++   F+       G LSG++ K VL+ S L   +L ++W+LSDID DG L  +EF VAM+LV +A     +PS +P  LVPP+
Sbjct:   32 GRVGASEAALFLKKSGLSDLTLGKIWDLADADRKGWLDKQGFYVALRLVACAQNGHEIALSALSHVIPPP---AFQDTGSPQLGSSA---------------------------------------QNPEAFWVVKPDEKTKFDGIFDSLG-PANGLLSGEKVKPVLINSNLPMEVLGKVWDLSDIDKDGHLDRDEFAVAMHLVYRALDKEPVPSVIPPKLVPPA 213          

Query:  149 VKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKL-EGIELPNVLPKEMLVPPDSFPFSDLGANEIFSS 412
            + G +SGL+ K+   +S L   +L +IW+LAD  Q G+++  +F++ M+LI +K+ +G++ P  L  +M+ P +    +  GA+ + S+
Sbjct:  305 MDGLVSGLEVKDIFMQSGLPQAVLAQIWALADTRQQGKLTQDQFAL-MYLITQKVSKGVDPPVTLNADMMPPSERGVSTTDGASGVGSA 392          

Query:  560 MQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALP-SKLPETLVPPSM 832
            + +  P Y   +   D    G +   EA   L +SGLS+  L +IW+L+D D  G L  + F VA+ LV  A+ G  +  S L   + PP+ 
Sbjct:   12 LSSGNPVYEKYYRLVDPGNNGRVGASEAALFLKKSGLSDLTLGKIWDLADADRKGWLDKQGFYVALRLVACAQNGHEIALSALSHVIPPPAF 103          

Query:  215 ILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPPDSFPFSDL-GANEIFSSKAAPSYNEVMAKDKADRQSFREKP--------PIPQDIQSTFPPLPKR------TSPQ-------------------------------TDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPS 829
            +L    +LAD++ DGRM   EFSIAM LIK +L G  LP VLP  +L      PF  L G   +     +     V     A   S    P        P+   +Q    P P        T P+                                DW + Q+ R +YR  FN  D+    FL+G +A+ +L+QS L+   LA IW LSDID DGKLT EEF +AM+L++ A +G+ LP  L   L+PPS
Sbjct:    1 LLCSCRALADLNGDGRMDAQEFSIAMKLIKMRLHGHALPAVLPPAIL---QRSPFGPLVGGAPLLGMGGSLGSTLVGGPLGAVAPSSLTPPLSTVGIPAPMANGVQGLMQPFPTTGHSCGATLPKGSTFGRPGAGVGPGIGPIQMQKALSAEATMAADWAVPQSSRLKYRQLFNSHDKTMSSFLTGPQARNILMQSHLTQPQLAAIWGLSDIDQDGKLTAEEFILAMHLIDMALSGQQLPPALTADLMPPS 248          

Query:   89 WSISTEEFSQHRIQF-EHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVP 361
            W++      ++R  F  H   +  F++G QA+  L +S L+   L  IW L+D+DQDG+++  EF +AMHLI   L G +LP  L  +++ P
Sbjct:  156 WAVPQSSRLKYRQLFNSHDKTMSSFLTGPQARNILMQSHLTQPQLAAIWGLSDIDQDGKLTAEEFILAMHLIDMALSGQQLPPALTADLMPP 247          

Query:   74 GNQSQWSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPPD-----------SFPFSDLGANEI-FSSKAAPSYNEVMAKDKADRQSFREKPPIPQDIQSTFPPLPKRTSPQTDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGR 787
            G    W++  EE ++    ++ L P  G +SG + K  L  SKL  + LG++W L+D+D+DG +   EFS+AM+L+ + LE   +P  LP + L+PP            + P   + A  + F+  A    N+++AK     Q FR              PL +  +      +  A R +Y   F + D++  G ++G E K V +++GLS ++LAQIW LSD    GKLT ++F +AM+LV Q + GR
Sbjct:  116 GPDIPWAVKPEEKAKFDSIYDSLKPQNGLLSGEKVKPVLLNSKLPVETLGRVWDLSDIDRDGFLDRDEFSVAMYLVYRALEKEPVPLALPIK-LIPPAKRKPGLVSSAFALPKVQVSACSLAFAFTALFEANKLLAKHS---QRFR--------------PLWQSQA------VSAAERLKYDEMFTKLDKDGDGQVTGLEVKEVFMKTGLSPAVLAQIWALSDTRQCGKLTRDQFGMAMHLV-QEKIGR 340          

Query:  155 GFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLI-------KKKLEGIELPNVLPKEMLVPPDSFPFSDLGANEIFSSKAAPSYNEVMAKDKADRQSFREKPPIPQDIQSTFPPLPKRTSPQTDWVIMQAVRPRYRLQFNQQDRNKK---GFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPS 829
            G +   QA  +L KS L +  LGKIW +AD +  G +    F +A+ L+          L  ++ P  +PK  L  P               +  AP                      PQ              P   W    AV+P  + +F+    + K   G LSG++ K VLL S L    L ++W+LSDID DG L  +EF VAMYLV +A     +P  LP  L+PP+
Sbjct:   32 GQVGAAQAVVFLKKSGLPDLTLGKIWEVADPEGKGYLEKQGFYVALRLVACAQNALNVSLSSLDFPVPVPKFELDSP---------------AMIAP----------------------PQ-------------GPDIPW----AVKPEEKAKFDSIYDSLKPQNGLLSGEKVKPVLLNSKLPVETLGRVWDLSDIDRDGFLDRDEFSVAMYLVYRALEKEPVPLALPIKLIPPA 212          

Query: 3476 ELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYV------RFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDV---HPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTN----SLGHRKLIYSGTL 4153
            EL  TEK + ++L+ ++ VF+   + + +LT  E   IFIN  +++P   +   A++  ++ S   Q +  +GD++L+ F      V      +FCSLQ+QA+ ++  K++   +F++   + E   +C+++ +  + L  MQR+TKY L+++NILK T+     HPD   + +A    R +   VNE +RE EN++RLE  Q  +    L E+ Y    T+     L H+K++Y G L
Sbjct:  721 ELFHTEKKHVQNLKVLYEVFFS--RLAPVLTNNETYQIFINLDEILPIHESLNEAMRKIREKS---QVVAEIGDLMLARFDGEAGEVLKAATAKFCSLQSQALDIVRSKQKKDPRFQQLMMEAESKPKCRRLQLKDFMLTEMQRLTKYPLLLQNILKYTQVRTVEHPDHKKLHKAGECCRRILNDVNETVRETENAQRLEDYQRRLDLSSL-ERSYNPLVTDFKNLDLTHKKMLYEGPL 953          

Query: 3437 LTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMAL-KIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLLVTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLIMAGSPSNQNCSLSITAS-TGVFGN 4402
             +  E +RQ  I EL + E+   EDL+   + + +P+ K +++T  EL  IF     LIP   +    L K RK N   ++    VG IL+   P    Y  +C+ Q  A ALL++KKQ   + ++F Q+C E+   +K+ + S+   P  R+ KY L++  IL++T + HPD   +EEA++  + +   VN    E E      + +D +  D L+E+        S   R L   G L +   G +L   LF D L+L  P+   N             C   +++Y++PI L  + +       Q+  + +  S  G FGN
Sbjct:  105 FSRSEIKRQEAIFELAQGEQDLIEDLKLAKKAYRDPMLKLSIMTAVELAQIFGALDSLIPLHEDLLTGLQKARKPNGATER----VGHILVEWLPCLNAYTCYCANQVAAKALLDQKKQ-DPRVQDFLQRCLESPFSRKLELWSFLDVPRSRLVKYPLLLREILRHTPNEHPDQQCLEEAISIIQGVVADVNTRTGESECC----YFRDKL--DYLDERQRDPLIATS---RTLHLHGEL-RNNRGTKLFVLLFGDVLVLSRPASRGN----------DGCC---YQVYRQPIPLRDLRLE----DLQDGEVKMGGSFRGAFGN 396          

Query:  161 ISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEG----IELPNVLPKEMLVPPDSFPFSDLGANEIFSSKAAPSYNEVMAKDKADRQSFREKPPIPQDIQSTFPPLPKRTSPQTDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLV 820
            ++G +AK+   K++L NQ LG+IW+L D D  G +   EF +AM+LI+  +         P VLP ++    DS     +  N+       P+    ++ +     S      I +     F      ++  +DW +    + ++   F+  D+   G LS        L S L+   LA IW+L+DI ++ + T  EF +AM+L+++  AG  LP  +P  L+
Sbjct:  153 VAGDKAKDIFLKARLPNQTLGEIWALCDRDASGVLDKSEFIMAMYLIQLCMSHHPSMNTPPAVLPTQLW---DSIRLEPVVVNQ-------PNRTTPLSANSTGVSSLTRHSTISRLSTGAF------SNAASDWSLSFEKKQQFDAIFDSLDKQHAGSLSSAVLVPFFLSSRLNQETLATIWDLADIHNNAEFTKLEFAIAMFLIQKKNAGVELPDVIPNELL 360          

Query:   83 SQWSISTEEFSQHRIQFEHLNPV-KGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEM-------LVPPDSFP 376
            S WS+S E+  Q    F+ L+    G +S      +   S+L+ + L  IW LAD+  +   +  EF+IAM LI+KK  G+ELP+V+P E+       L PP+  P
Sbjct:  269 SDWSLSFEKKQQFDAIFDSLDKQHAGSLSSAVLVPFFLSSRLNQETLATIWDLADIHNNAEFTKLEFAIAMFLIQKKNAGVELPDVIPNELLQSPALGLYPPNPLP 374          

Query:  581 YRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQ 772
            Y  +F+Q D    G ++G+  + +   SGL   +L+Q+W   DID+ G L   EF  A+ ++ Q
Sbjct:   18 YNQKFHQLDTEDLGVVTGEAVRPLFASSGLPGQLLSQVWATVDIDNKGFLNLNEFSAALRMIAQ 81          

Query: 3470 IRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHV------QCDGLNEKLYFN----STTNS 4117
            I+E + TE+ Y  DL E+   + + +  SNL+T EEL  +F N  D I     F ++L+I      +KQ I   G + + +   F +Y  +   QN AI  L     +S   K    + +  +   K+ + S+  KP+QR+ +Y L+V+ +L  + D + +  ++E A+  ++++  ++NE  R  EN + ++ +   V      +     E LYF+    STTNS
Sbjct:  283 IKEFVATERKYVHDL-EILDKYRQQLLDSNLITSEELYMLFPNLGDAIDFQRRFLISLEINALVEPSKQRI---GALFMHSKHFFKLYEPWSIGQNAAIEFL-----SSTLHKMRVDESQRFIINNKLELQSFLYKPVQRLCRYPLLVKELLAESSDDN-NTKELEAALDISKNIARSINENQRRTENHQVVKKLYGRVVNWKGYRISKFGELLYFDKVFISTTNS 498          

Query:   44 FKNNTISIMLGNQSQWSISTEEFSQHRIQFEHLNP-VKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPPDSFPFSDLGANEI----FSSKAAPSYNEVMA 445
            F NN    ++ N SQ  ISTEE S     FE  +   KG +    A E   KS L+   L +IW+L D++  G+++  EF++ MHL+  KL G  +PNVLP  ++  P S    D   N++     ++K  PS+ ++ A
Sbjct:  583 FNNN----LIDNSSQDKISTEEKSLFYKIFETFDTQNKGLLDSPTAVEIFRKSGLNRADLEQIWNLCDINNTGQLNKQEFALGMHLVYGKLNGKPIPNVLPSSLI--PSSTKLLDNLKNQLKTEPTTTKEKPSFGKIDA 715          

Query:  167 GLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEM-LVPPDSF----PFS----DLGANEIFSSKAAPSYNEVMAKDKADRQSFREKPPIPQDIQSTFPPLPKRTSPQTDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSMVTISN 847
            G+     LT   L +Q  G   S+    Q G  S+   S     ++ +L G++     P+    +PP +F    P +      G NEI++       N ++     D+ S  EK        S F                      Y++ F   D   KG L    A  +  +SGL+ + L QIWNL DI++ G+L  +EF + M+LV     G+ +P+ LP +L+P S   + N
Sbjct:  496 GVNLGPQLTGGALQSQYTGGYGSVMP-QQSGPASMPNLSFNQQGLQSQLTGLQ-----PQPTGFLPPSNFSATMPLTAQKTGFGNNEIYTKSNF--NNNLIDNSSQDKISTEEK--------SLF----------------------YKI-FETFDTQNKGLLDSPTAVEIFRKSGLNRADLEQIWNLCDINNTGQLNKQEFALGMHLVYGKLNGKPIPNVLPSSLIPSSTKLLDN 692          

Query:  611 NKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKL 805
            N    +SG   + +L++SGL  S LA+IW L D    G+L   EF +AM+L+     G  +P +L
Sbjct:  284 NGSNTVSGANCRKILMRSGLPPSQLARIWTLCDTSKAGELLFPEFALAMHLINDVLQGDTIPYEL 348          

Query: 3437 LTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLE----ELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQ-CEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNT--EDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLG----HRKLIYSGTLYK---AKSGKELVG---FLFNDFLLLVTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLIMAG 4342
            L + E +RQ  I E+  TEK + + L+     F + + ++N+++ +     +KH+F +  D+   +  F  AL  R+ +S     ++ +GDI+L   P F  +V + + +  A  L+E ++  +  F  F       +LR     + S+  + + R  +Y L+V+ I+K+T  E    D  D+ +A+ A R   + +++              QD      L +K+ F +   +LG     RK+ + G L +   +KS   +VG   F   D +LL   +   N +              Q K++++PI L  +    G
Sbjct:  653 LPKKEIKRQEAIYEVYITEKNFVKSLEITRDTFMKTLAETNIISADIRKNFIKHVFAHINDIYSVNRRFLKALTDRQRSS---PVVRGIGDIVLRFIPFFEPFVSYVASRPYAKYLIETQRSVNPYFARFDDDMMSSSLR---HGIDSFLSQGVSRPGRYMLLVKEIMKSTDPEKDKSDYEDLSKAMDALRDFMKRIDQASGAA---------QDRHDVKLLKQKILFKNEYVNLGLNDERRKIKHEGILSRKELSKSDGTVVGDIQFYLLDNMLLFLKAKAVNKW-------------HQHKVFQRPIPLPLLFACPG 943          

Query: 2378 EYCLALYPYESTVPGDLTMRPGDIIQIVD-MSTHWWKGHIRGARENGMFPSHYVK 2539
            EY  ALY ++    GDL ++PGD +Q+++ +S  W+KG   G    G+FP++YVK
Sbjct:   57 EYVEALYQFDPQQDGDLGLKPGDKVQLLEKLSPEWYKGSCNG--RTGIFPANYVK 109          

Query: 3905 LIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLLVTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLIMAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIR--RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDL 4948
            L +  ILK+T D+HPD  ++E A+  A  LC  VNEG+R +ENS+RLEW+Q+HV+ +GL E+L FNS TN LG RKL++SGTL+K KSGKEL  FLFNDFLLL  P     G         S+   +Q+ +Y+KPI LN V++    P++ N               S   +F++      +  KA S  DR++W+E+L  A+  YIETE  +R+     R  R++G+G+L+VT++EG +LKSS  P   +  YCE S+G+Q  +T+V   T NPKWN  M F +K++E DVLC++ +D+++F+PNDFLGRTEV L  + +     KGP   RL L  V +GE++VKL+L
Sbjct:   28 LYLSEILKHTPDIHPDRMNLEIALEKAEELCNQVNEGVRSQENSDRLEWLQNHVKREGLGEQLIFNSATNCLGPRKLLHSGTLFKVKSGKELKAFLFNDFLLLTRPQSTITGTLSKKIGFESNDASIQYTIYRKPIFLNEVVV--KRPADMN---------------SEEPVFSVSHIDRVYTFKAESKGDRNRWIEKLEKAAEHYIETERFMRQKMHRTRSIRTSGIGKLVVTIVEGVDLKSSD-PSGMSDPYCEVSMGSQEHKTRVCPQTLNPKWNSTMTFTVKDMEQDVLCITVFDRDFFSPNDFLGRTEVSLASLLK---KGKGPWHERLLLHEVTTGEVLVKLEL 356          

Query: 4568 RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDL 4948
            R++G+G+L+VT++EG +LKSS  P   +  YCE S+G+Q  +T+V   T NPKWN  M F +K++E DVLC++ +D+++F+PNDFLGRTEV L  + +     KGP   RL L  V +GE++VKL+L
Sbjct:    4 RTSGIGKLVVTIVEGVDLKSSD-PSGMSDPYCEVSMGSQEHKTRVCPQTLNPKWNSTMTFTVKDMEQDVLCITVFDRDFFSPNDFLGRTEVSLASLLK---KGKGPWHERLLLHEVTTGEVLVKLEL 126          

Query: 4568 RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDL 4948
            R++G+G+L+VT++EG ++KSS  P   +  YCE S+G+Q  +T+V   T NPKWN  M F +K++E DVLC++ +D+++F+PNDFLGRTEV L  + +     KGP   RL L  V +GE++VKL+L
Sbjct:    4 RTSGIGKLVVTIVEGVDIKSSD-PSGMSDPYCEVSMGSQEHKTRVCPQTLNPKWNSTMTFTVKDMEQDVLCITVFDRDFFSPNDFLGRTEVSLASLLK---KGKGPWHERLLLHEVTTGEVLVKLEL 126          

Query: 3437 LTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFI------VYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQ---CDGLNEKLYFNSTTNSLGHRKLIYSGTL 4153
            L + E +RQ +I ELI TEK +  +L+ + +VF++P+KK N++  E +K +F N  +LI    +   ++K R+      + IQC+GDI+L+ F N            FC+ Q  A+  L ++++   K  +F   CE +  C+++ ++       QR+TKY L++E I KNT    PD  D+E A+  A+ L   VN+ ++E EN +RLE  Q  V     D    K      T     +KLIY G L
Sbjct:    7 LKQKEIKRQEFIHELIYTEKTHVRNLKVLDKVFHKPMKKMNIMPYEYIKKLFPNLQELIEIHGDLLQSMKKRE---AEGEVIQCIGDIMLNRFDNEAGEAAKQACATFCNYQKNALEELRQRQKKDPKLLQFIMNCEASPLCRRLKLNEIISTSYQRLTKYPLLLEGIGKNTPSSLPDSRDIERAIQCAKDLLAFVNQSVKECENQQRLEEFQKKVDRKPMDSATNKQMEEFKTLDFSKKKLIYDGPL 251          

Query: 2822 AKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNEGWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQP---GDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLI 3613
            A +V  Y+A + D+LS  PGQ + +       W++ +L   G   +  +           F  +H   L                P   +S       QP   G++++AM+PY+AQ  DEL+F K S+  ++SKD  EWW+G       +G+FP NYV+      S  D  +  S +  +   + A                    A +++ E+ RQ  I ELI +E+AY + L     VFY P+ +S LLT  E+  IF+NW ++I
Sbjct:   73 ATVVSPYTAIAADQLSLAPGQLIRVTRKDPSGWWEGELQARGKKRQSGI-----------FPANHVKILAKG-------------PGGSQSGSCTSTQQPPEGGNQVLAMFPYTAQKGDELTFYKGSVFNVMSKD-GEWWKGE--LNGQVGMFPSNYVQ------SLGD--LPASTKQWTGSFDAA------------------ILASMSDTERMRQNAIYELINSEQAYMDQLSLTLEVFYNPLAESGLLTANEMNTIFVNWKEII 286          

Query: 1745 ALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNVFDQTLPDGATIKKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKL 2545
            ALY + G + D L+F+ GD+I +           W  GRL+ N  +GLFP  YVKK +  + + L L            N       + AT+           + P+   A     DQLS   GQ IRV  +    WW+GE+    +  G     G FP  +V+ +                       +    G+     TST      G   LA++PY +    +LT   G +  ++     WWKG + G  + GMFPS+YV+ L
Sbjct:    4 ALYTYNGEEGD-LSFKEGDVIGI-----TKDEGEWWEGRLREN--YGLFPANYVKKKEAERKSTLSL------------NSLFCLFSEIATV-----------VSPYTAIA----ADQLSLAPGQLIRVTRKDPSGWWEGEL----QARGKKRQSGIFPANHVKIL-----------------------AKGPGGSQSGSCTSTQQPPEGGNQVLAMFPYTAQKGDELTFYKGSVFNVMSKDGEWWKGELNG--QVGMFPSNYVQSL 206          

Query: 2384 CLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGAREN-GMFPSHYVKK 2542
            C+ALY Y     GDL+ + GD+I I      WW+G +   REN G+FP++YVKK
Sbjct:    2 CVALYTYNGE-EGDLSFKEGDVIGITKDEGEWWEGRL---RENYGLFPANYVKK 51          

Query: 3128 KLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLLV--TPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLI-MAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIR--RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFF 4957
            ++IAMY Y+A N DELSF+K  ++ I+ K  P+WW+G      + GL P NY++           + ++S  +PS +              W  D ++  +  +T  E++RQ YI ELI+TE+ Y EDL+ V  VF++P+ +S  LT  E+  IF+NW  LI  ++ F  AL+ RK   G   PIQ +GD+L S       Y+ FCS Q  A ALL+ K      FK+F ++   N RCK MP+SS+ LKPMQRIT+Y L+++NIL+NT + H D G + EA+  A  LC  VNEG+REKENS+RLEW+Q H+QC+G  E L FNS TN LG RKL++SG LYK K  +EL  FLFNDFLLL   T  ++ +G   +F  +TS+    Q KMYK P+ LN VL+ M   PS                  S   +F +      + LK  ++++R  WV+++ AAS  +IETE   RE +   R  +++G+GRLLVT++E   LK+   P  K++ YCE ++G Q   ++  S T NPKWN   QF I ++  DVLC++ ++K+ F+P+DFLGRTEV +  IK+  +  KG   RRL L  V +GE+ VKLDL  +
Sbjct: 1013 QVIAMYDYTAANQDELSFSKGQLINILDKTNPDWWKGE--VNGVTGLLPTNYIK-----------MTTES--DPSQQ--------------WCAD-LMTLDT-MTPQERKRQGYIHELIQTEETYVEDLELVLEVFHKPMSESGRLTEAEMATIFVNWRKLIMCNHKFLKALRARKKTGGENMPIQLIGDVLASELAQMHPYICFCSGQLNAAALLQSKTNNQPDFKDFLRKIATNYRCKGMPLSSFLLKPMQRITRYPLLIKNILENTPESHADHGPLREALERAEELCFQVNEGVREKENSDRLEWMQSHIQCEGPIENLVFNSLTNCLGPRKLLHSGRLYKTKGTRELWAFLFNDFLLLTHSTKHFSFSGSDKLFSPKTSA----QLKMYKTPLFLNEVLVKMPPDPS------------------SDEPVFHVSHIDRVYTLKTETLSERATWVQKIKAASEHFIETEKKKREKAYQARSLKTSGIGRLLVTIIEAQELKACK-PNGKSNPYCELTMGAQCYTSRPASDTPNPKWNFSCQFFINDLYQDVLCITVFEKDQFSPDDFLGRTEVPVATIKK-DMETKGAANRRLLLHEVPTGEVWVKLDLQLY 1572          

Query:  548 DWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSM 832
            DW + QA R +YR QFN  D+   G+LSG + +  L+ S L+ + LA IW L+D+D DG+L  +EF +AM+LV+ A+ G  LP  LP+ LVPPS+
Sbjct:  244 DWAVPQASRLKYRQQFNTLDKLMSGYLSGPQVRNALMASNLTQTQLATIWYLADVDKDGQLRADEFILAMHLVDMAKTGYPLPLTLPQDLVPPSL 338          

Query:   89 WSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPPDS 370
            W+I+ EE  +H  QF+ L+P+ G++SG QA+++  +S L   +L +IW+L+D+D DG+M   EFSIAM LIK +L+G  LP+ LP  M  PP+S
Sbjct:   14 WAITPEERGKHDKQFDSLSPILGYVSGEQARKFFLQSGLPASVLAEIWNLSDLDSDGKMDRLEFSIAMKLIKHRLQGWNLPSSLPTIMKQPPNS 107          

Query:  551 WVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSMVTISNNNKSLP 865
            W I    R ++  QF+       G++SG++A+   LQSGL  S+LA+IWNLSD+DSDGK+   EF +AM L++    G  LPS LP  +  P      N+N S P
Sbjct:   14 WAITPEERGKHDKQFDSLS-PILGYVSGEQARKFFLQSGLPASVLAEIWNLSDLDSDGKMDRLEFSIAMKLIKHRLQGWNLPSSLPTIMKQP-----PNSNSSGP 112          

Query:   89 WSISTEEFSQHRIQFEHLNPV-KGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPP 364
            W++      ++R QF  L+ +  G++SG Q +  L  S L+   L  IW LADVD+DG++   EF +AMHL+     G  LP  LP++ LVPP
Sbjct:  245 WAVPQASRLKYRQQFNTLDKLMSGYLSGPQVRNALMASNLTQTQLATIWYLADVDKDGQLRADEFILAMHLVDMAKTGYPLPLTLPQD-LVPP 336          

Query: 1730 LESYQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLD---------PVQSNELVLTPDSETSTDKEQN-VFDQTLPDGATIKKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQ-PVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQI-VDMSTHWWKGHI--RGAR-ENGMFPSHYVKKL 2545
            L +Y+ALY F  R  DEL+ +A  +I V N      P GWLCG     +  G FP  Y +K           P    +  L P+++     +Q  +F   +    ++      +   AI  W       +   LS +    I V++++  +WW G++      +G   + GWFPR YV   +D S E         + S L  +A   +F   IS   S   +    E   ++   E+  P  L + PG +I I    ST WW G +  RG + + G F S +VK L
Sbjct:  743 LTTYKALYSFVARNADELSIDANCLIQV-NELTVGEP-GWLCGTYCGKR--GWFPQSYAEKCPTFLTSEAAAPAAGKKSCLQPNTKYEAKVKQFWIFSLKVVSSCSV-----TLLARAISSW----SATSGVLLSLSQDDIITVLQQRD-EWWLGQL------NG---TQGWFPRSYVTLEMDGSGEY-----DDPEASRLGASAKKPVFLLLISDLYSVWST----EIAQSVVTAEAPAPHQLLLSPGQLIVICAKNSTGWWLGELQARGKKPQRGWFHSSHVKLL 997          

Query: 3437 LTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLLVTPS--YNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLIMAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIR--RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFF 4957
            L+  EK+RQ YI EL++ E+ Y +DLQ V  VF++P+ +S  LT  E+  IF+NW +L+  +     AL++RK  +G   P+Q +GDIL +   +   Y+ FCS Q    +LL+ +      FKEF ++   + RCK MP+SS+ LKPMQRIT+Y L ++NIL +T + H D G ++EA+  A  LC+ VNEG+REKENS+RLEWIQ+HVQCDG  E L FNS TN LG RKL++SG +YKAKS KEL  FLFNDFLLL   +  ++++G   +F    S+   +Q KMYK P+LLN +L      S+   +  IT    V                  +VLK  ++N+R  WV+++ AAS ++IETE   RE +   R  + +G+GRLLVT+LE   LK++  P  K++ YCE ++G Q+  ++ ++ T NPKWN   QF +K++  DVLC++  D+  F+P++FLGRTE+ +  IK+ ++ NKG + RRL L  V +GE+ V+LDL  +
Sbjct:   21 LSPLEKKRQGYIHELMDAEEKYVDDLQVVLEVFHKPMSESGRLTDSEMAMIFVNWKELLACNTKLVKALRVRKKTTGENMPVQMIGDILAAELSHMQPYISFCSCQINGASLLQTRTDNEPDFKEFLKKLGTDYRCKGMPLSSFLLKPMQRITRYPLHIKNILDSTIEGHADRGPLKEALERAEELCQQVNEGVREKENSDRLEWIQNHVQCDGPAENLVFNSLTNCLGPRKLLHSGKMYKAKSNKELWAFLFNDFLLLTHAAKQFSSSGPDKLF----SNRNNVQLKMYKPPVLLNEILAKISDSSSDEPTFQITHIDRV------------------YVLKTENINERTAWVQKIKAASEEFIETELKKREKAYQGRSIKVSGIGRLLVTILEATELKATR-PNGKSNPYCEVNVGAQVFTSRTLNDTLNPKWNFSCQFHLKDLYQDVLCITISDRAQFSPDEFLGRTEIPVATIKK-EMENKGSVTRRLLLHEVPTGEVWVRLDLQLY 507          

Query: 4088 KLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLL--VTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLI-MAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIR--RSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFF 4957
            +L FNS TN LG RK ++SG L+KAKS KEL GFLFNDFLLL  V     ++G   VF     S   +Q++MYK PI LN VL+ +   PS                      +F I      + L+A S+N+R  WV+++ AAS  +IETE   RE +  +R  R+ G+GRL+V ++EG  LK   +  TKT       LG    RT     T NPKWN + QF IK++E DVLC++ ++++ F+P+DFLGRTE+ L +IK+ +  +KGPI +RL L  V +GE++V+LDL  F
Sbjct:   11 QLVFNSVTNCLGPRKFLHSGKLFKAKSSKELYGFLFNDFLLLTQVIKPLGSSGSDKVF-----SKTHLQYRMYKTPIFLNEVLVKLPTDPSGDE------------------PLFHISHIDRVYTLRAESINERTAWVQKIKAASELFIETEKKKREKAYLVRSQRATGIGRLMVNIVEGIELKPCRSHGTKT-------LGVHTIRT----DTLNPKWNSNCQFFIKDLEQDVLCVTVFERDQFSPDDFLGRTEIRLAEIKKDQ-GSKGPITKRLLLHEVPTGEIVVRLDLQLF 270          

Query:   41 CFKNNTISIMLGNQSQWSISTEEFSQHRIQFEHLNP-VKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPPDSFPFSDLGANEIFSSKAAPSYNEVMAKDKADRQSFREKPPIPQDIQSTFPP-----------LPKRT-------------------SPQ--TDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAG 784
            C K N + +       ++IS +E ++H  QF  L+P   GFI+G QA+ +  +S LS  IL +IW+LAD++ DGRM +HEFSIAM LIK KL+G  LP+ LP  M  P    P         F+ K+  +  +      +        PP+PQ I +  PP           LP +                    SPQ  TDW + Q+ R +YR  FN  D+   G L+G +A+ +L+QS L    LA IW+LSDID DGKLT EEF +AM+L++ A +G
Sbjct:    2 CVKMNVLLLFASGPDVFTISVDERAKHDQQFHGLSPSAGGFITGDQARNFFLQSGLSPPILAQIWALADMNSDGRMDIHEFSIAMKLIKLKLQGHPLPSALPPSMKQPLLPLPPQTTFGECSFTPKSLSNCADNSVVFMSPPLVSTAPPPLPQPIANGAPPTALMPPLSGFSLPGKLLLVSNLHCVFYSSSFCSAPSPQPPTDWAVPQSSRLKYRQLFNSHDKMMSGHLTGPQARTILMQSSLPQGQLATIWSLSDIDQDGKLTAEEFILAMHLIDMAMSG 282          

Query:  572 RPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPP 826
            R ++  QF+    +  GF++GD+A+   LQSGLS  ILAQIW L+D++SDG++   EF +AM L++    G  LPS LP ++  P
Sbjct:   25 RAKHDQQFHGLSPSAGGFITGDQARNFFLQSGLSPPILAQIWALADMNSDGRMDIHEFSIAMKLIKLKLQGHPLPSALPPSMKQP 109          

Query:   56 TISIMLGNQSQWSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPPDSFPFSDL---GANEIFSSKAAPSYNEVMAKDKADRQSFREKPPIPQDIQSTFPPLPKRTSPQTDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQ-ARAGRALPSKLPETLVPPSMVTISN 847
            T S  L +  QW+I  +E  +    FE L+PV+G +SG + +  L  SKL   +LGKIW L+DVD+DG +   EF +AMHL+ + +E   +P  LP   L+PP     S +   GA  +  S +    + V  K+     S            S  P     + P+  W +  A R RY   F + D +  G ++G +   + +QS LS ++LAQIW L+D    GKLT E+FC+AM+L+ Q +  G   PS L   ++PPS  T S+
Sbjct:  100 TRSSTLASDPQWAIRPDEKGKFEGIFESLSPVQGLLSGDKVRPVLINSKLPLDVLGKIWDLSDVDKDGHLDKEEFIVAMHLVYRAMEKEAVPASLPAN-LIPPSKRKKSAMALPGAVAVLPSLSGLLSSPVTLKETLLSSSPAPA-SASAAKLSPKPSFKSSSEPEVKWAVPAADRARYEDLFKKTDTDNDGLVTGGDVIEIFMQSTLSQTMLAQIWGLADTKHTGKLTREQFCLAMHLIHQKSTKGIDPPSSLTPDMIPPSERTESS 365          

Query:  581 YRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAG 784
            Y L + Q D    G +S  EA   L +SGL +S L +IW+L+D D  G L  + F +A+ LV  A+AG
Sbjct:    8 YELYYRQLDPGNTGKISAAEAAQFLKKSGLPDSTLGKIWDLADSDRKGFLDKKGFFIALRLVASAQAG 75          

Query:   68 MLGNQSQWSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPPDSFPFSDLGANEIFSSKAAPSYNEVMAKDKADRQSFREKPPIPQDIQSTFPPLPKRTSPQTDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSMVTISNNNKSLPNSHTEHEWTATSESRPGTLKACPASPQIIQETSMNTAQWNKPLPVTPEIEIQSQIHQKLEKEKQRLIDLEETRLQQAVXXXXXXXXXXXXXXDRQEFLIDALAMEEEKCQMYQAKLKESLQSVESHKAHIELMRNERDELVDSTSCLFEELEAAKAEHSRCQRDRXXXXXXXXXXXXXXPFQNDLLQLENLKQLHKQSISNLHQEIIDLQASIDLKSQNVVRNSNKLHNLENAVNCHQLAEIRRLRSNIQSKRNEVMEILEKQTQNNDVKPIFDFHQTNGHKLPDEFDLESYQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNVFDQTLPDGATIKKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQTIDTISSDYYTALSLENSNSPTMTYDDIGRNLNDFDTDSGITDPELATPAEIGENAAYSNYCTLAXXXXXXXXXXXXXXXLSKAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNEGWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLLVTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLIMAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIRRSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFFRYD 4966
            MLGNQSQWSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPPDSFPFSDLGANEIF+SKAAPSYNEVMAKDKADRQSFREKPPIPQDIQSTFPPLPKRTSPQTDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSMVTISNNNKSLPNSHTEHEWTATSESRPGTLKACPASPQIIQETSMNTAQWNKPLPVTPEIEIQSQIHQKLEKEKQRLIDLEETRLQQAVEERNREKELLKKIKDRQEFLIDALAMEEEKCQMYQAKLKESLQSVESHKAHIELMRNERDELVDSTSCLFEELEAAKAEHSRCQRDRNNLELKLNQELQSNPFQNDLLQLENLKQLHKQSISNLHQEIIDLQASIDLKSQNVVRNSNKLHNLENAVNCHQLAEIRRLRSNIQSKRNEVMEILEKQTQNNDVKPIFDFHQTNGHKLPDEFDLESYQALYKF GRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNVFDQTLPDGATIKKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPISPNTSTTHSNSSGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQTIDTISSDYYTALSLENSNSPTMTYDDIGRNLNDFDTDSGITDPELATPAEIGENAAYSNYCTLAESSDGEDSNNSNQNSLSKAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNEGWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLLVTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLIMAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIRRSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFFRYD
Sbjct:    1 MLGNQSQWSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVLPKEMLVPPDSFPFSDLGANEIFNSKAAPSYNEVMAKDKADRQSFREKPPIPQDIQSTFPPLPKRTSPQTDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSMVTISNNNKSLPNSHTEHEWTATSESRPGTLKACPASPQIIQETSMNTAQWNKPLPVTPEIEIQSQIHQKLEKEKQRLIDLEETRLQQAVEERNREKELLKKIKDRQEFLIDALAMEEEKCQMYQAKLKESLQSVESHKAHIELMRNERDELVDSTSCLFEELEAAKAEHSRCQRDRNNLELKLNQELQSNPFQNDLLQLENLKQLHKQSISNLHQEIIDLQASIDLKSQNVVRNSNKLHNLENAVNCHQLAEIRRLRSNIQSKRNEVMEILEKQTQNNDVKPIFDFHQTNGHKLPDEFDLESYQALYKFSGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNVFDQTLPDGATIKKAPNNVWVEAIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPISPNTSTTHSNSSGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQTIDTISSDYYTALSLENSNSPTMTYDDIGRNLNDFDTDSGITDPELATPAEIGENAAYSNYCTLAESSDGEDSNNSNQNSLSKAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNEGWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLLVTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLIMAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIRRSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFFRYD 1633          

Query: 2069 MDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQTIDTISSDYYTALSLENSNSPTMTYDDIGRNLNDFDTDSGITDPELATPAEIGENAAYSNYCTLAXXXXXXXXXXXXXXXLSKAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNEGWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLLVTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLIMAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIRRSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFFRYD 4966
            MDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPISPNTSTTHSNSSGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQTIDTISSDYYTALSLENSNSPTMTYDDIGRNLNDFDTDSGITDPELATPAEIGENAAYSNYCTLAESSDGEDSNNSNQNSLSKAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNEGWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLLVTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLIMAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIRRSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFFRYD
Sbjct:    1 MDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTESTMKYSNLNFAASNDIFGAPISPNTSTTHSNSSGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQTIDTISSDYYTALSLENSNSPTMTYDDIGRNLNDFDTDSGITDPELATPAEIGENAAYSNYCTLAESSDGEDSNNSNQNSLSKAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNEGWVPRYCIDKEETQFIRDHTNDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQPGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNFIVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLLVTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLIMAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIRRSAGVGRLLVTVLEGANLKSSSTPETKTHAYCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPNDFLGRTEVGLKDIKQAKLANKGPIERRLKLMGVNSGELIVKLDLAFFRYD 966          

Query:   68 MLGNQSQWSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVL-------------------------------------------PKEMLVPPDSFPFSDLGANEIFSSKAAPSYNEVMAKDKADRQSFREKPP---IPQDIQSTFPPLPKRTSPQTDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSK-----LPETL---------VPPSM----------VTISNNNKSLPNSHTEHEWTATSESRPGTLKA--------CPASPQIIQETSMNTAQWNKPLPVTPEI----------EIQSQIH----------------------QKLEKEKQRLIDLEETRLQQAVXXXXXXXXXXXXXXDRQEFLIDALAMEEEKCQMYQAKLKESLQSVESHKAHIELMRNERDELVDSTSCLFEELEAAKAEHSRCQRDRXXXXXXXXXXXXXXPFQNDLLQLENLKQLHKQSISNLHQEIIDLQASIDLKSQNVVRNSNKLHNLENAVNCHQLAEIRRLRSNIQSKRNEVMEILEKQTQNNDV---KPIFDFHQTNGHKLPDEFDLES-----YQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNV-------FDQTLPDGATIKKAPNNVWVEAIFPWIMDAE---DETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNE------TLLSTESTM-----KYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQT----------------IDTISSDYYTALSLEN-SNSPTMTYDDIGRNLNDFDTDSGITDPELATPAEIGENAAYSNYCTLAXXXXXXXXXXXXXXXLSKAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNE-GWVP-RYCIDKEETQFIRDHT--NDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQ-----PGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEK 3496
            ML N + W I++EE  +  +QF+ LNPV GFI+G QAK   TKS L   +LG+IW LAD D+DG M+ +EF+IAMHLIK+KLEG ELP+VL                                           P   +  P +  F +   +    S +  S +   A+  ++   F    P   +PQDI    PP+   TS   DWVI Q+VRPRYRLQFNQQDRNK+GFL+G EAKA+L+QSGL N+ LA IW+L+DID DG LTCEEFC+AM+LVEQAR+GR LP++     LP +L         +  SM          V+++ + +S   S  +   T   E R   LK              Q+ QE     A+    +    +I          EIQ Q+                        +LE EK+RL+++E+ RL+ A+ ER +E+E L ++  ++  LIDALA E+EK +  Q++++ +  ++E++KA I  MR  RD+L+D+T CL EELEAAKAE SRCQR++ NLEL+L   LQS+P    +  ++ LK  HK  I+                                 V    L++I++L++++  K+N  + IL+KQ +       K   +F +    K P    + S     Y+A+Y F GRQ DE++F+ GDII++         +GWL G L  +   GLFP +YV+KL    S E      ++T  D  QN+       F+  +    T++K+    W EAI+ W  ++     E P+QLSF  GQ I++I+    DWW GE      +  +   +GWFP+ YV+ +D  N       T+  T  ++     KYS+LN +   D+           T   S    C+A YPY+++V GDL ++PGDII+++D    WWKG+ R     G+FPS+YVK +T +DL + ++                ID +++  ++A+SL + +++P  T  D+  N       S +  P+   P  +  N A +                        A++V  ++  S +++    GQ + I + S   W+K ++   G     GW P +Y      +Q I   +  ND           T + S  +++ +  I+  ++     PGD LI MY YSAQN DELSF KN+I+ +I K+EPEWW GRN+ +S  GLFPVNYVRR Q   ++D+E + +     S    N    V GRP+SWY+DG + FNAILTEDEKRRQFYIRELIETEK
Sbjct:    1 MLNNPNLWFITSEEKVKFDVQFQCLNPVNGFITGNQAKSLFTKSNLPTDVLGRIWFLADYDKDGCMNSNEFAIAMHLIKRKLEGYELPDVLPLSLNPLQTNATTMSYSGYMPVSNTYNTMPVMHNTSHAMSNNNPNNTMAVPHASAFVNYSTSSTMKSFST-SLSTSNAQFGSNNIPFPINNPSYAVPQDINK--PPIHTVTS-DDDWVIPQSVRPRYRLQFNQQDRNKRGFLTGVEAKAILVQSGLPNTSLASIWSLADIDQDGNLTCEEFCIAMHLVEQARSGRQLPNQLPQSLLPPSLQKKNILGTSMSASMNIPINPITNGVSVTKSIQSEKESQQKSVLTGEDERRANYLKGQAELEKRRAILDEQMRQEEEGRKAKERAEIERLEKIRQEKEQARFAEIQRQMEIRRQQELEREEQLRRVAEEREKMRLESEKKRLLEMEKRRLEVAISERRQEQESLSEVNSKKGNLIDALANEKEKKRDLQSRIESTQITLETYKAGIGSMREHRDKLIDTTDCLREELEAAKAELSRCQREKQNLELQLQSNLQSDPVLEQIKTVQALKSSHKDKIN---------------------------QRFRKEVTSKLLSDIKKLQTSVCEKKNAAIAILKKQKEPKTAVSEKNYNEFDKIGISKNPQLNSMPSNELVYYEAIYAFEGRQHDEISFKTGDIIIINTQDQIEPSSGWLYGWLDNSSHCGLFPEIYVRKLSGPPSTE-----STQTKIDVNQNISSGFADLFNNDITPKGTLRKSSECQWAEAIYHWKPESNVTYGEYPNQLSFETGQLIKIIDTNLDDWWTGETTALDANGKEKIIMGWFPKTYVRLLDEQNANHPDSGTVTPTAGSLEDLASKYSSLNLSVKYDL----------NTFDGSQKLLCVARYPYQASVLGDLNIQPGDIIEVLDQKQDWWKGYNRNTNSQGLFPSNYVKIVTSEDLANTESAKFAEGVPVEEMSESIIDLMNASQHSAISLNSVTSNPYSTISDVENN-------SALYYPQNTVP--VNSNGASTPEI---------------------AQVVIEFNPLSAEQIPLQVGQLIQIREKSPSGWWKGEIQQRGQQRRIGWFPGQYVSIINSSQSIVSDSMYNDGSLTPPTCTTPTPMSSW-INQDTSSINSTIELNDSLPGDHLITMYNYSAQNVDELSFDKNAILVLIDKNEPEWWMGRNLLSSQEGLFPVNYVRRLQAGNASDEEAMKEVAVASSQYNVN----VAGRPVSWYVDGTMTFNAILTEDEKRRQFYIRELIETEK 1227          

Query: 3911 VENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLLVTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLIMAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIRRSAGVGRLLVTVLEGANLKSSSTPETKTHA-YCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPN 4816
             E ILK+TED HPD  DMEEAVAAARSLCE+VNEG+RE+ENSERLEW+Q+H+QC+ L+EKLYFNS TN LGHRKLI+SGTL K KSGKELVGFLFNDF LL TP YNT G PFVFPLETSS  KMQFKMYKKPI+LN+V+I +GSP++   S            FS ++IFT+KE   + +L+ALS NDRDKWVERL+ AS+ YI TEN  RE SMSIRR+AGVGRLLVTV+EG +L+SSS+ +      +CEASLGNQ+ RTKVV ST NPKWN  MQFLIKNI+ DVLCL+ Y+K+YFAPN
Sbjct: 1225 TEKILKHTEDNHPDRSDMEEAVAAARSLCESVNEGVRERENSERLEWLQEHMQCENLSEKLYFNSNTNCLGHRKLIHSGTLSKYKSGKELVGFLFNDFFLLATPCYNTGGMPFVFPLETSSKDKMQFKMYKKPIILNQVMISSGSPTSSANS-----------QFSSNDIFTVKEPTCEHILRALSQNDRDKWVERLMNASMFYINTENLKRECSMSIRRTAGVGRLLVTVVEGISLRSSSSHKDSKSDPFCEASLGNQLHRTKVVPSTLNPKWNTQMQFLIKNIDQDVLCLTVYNKDYFAPN 1516          

Query:   68 MLGNQSQWSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVL-------------------------------------------PKEMLVPPDSFPFSDLGANEIFSSKAAPSYNEVMAKDKADRQSFREKPP---IPQDIQSTFPPLPKRTSPQTDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRAL----------PSKLPETLVPPSM--------------VTISNNNKSLPNSHTEHEWTATSESRPGTLKA--------CPASPQIIQETSMNTAQWNKPLPVTPEI----------EIQSQIH----------------------QKLEKEKQRLIDLEETRLQQAVXXXXXXXXXXXXXXDRQEFLIDALAMEEEKCQMYQAKLKESLQSVESHKAHIELMRNERDELVDSTSCLFEELEAAKAEHSRCQRDRXXXXXXXXXXXXXXPFQNDLLQLENLKQLHKQSISNLHQEIIDLQASIDLKSQNVVRNSNKLHNLENAVNCHQLAEIRRLRSNIQSKRNEVMEILEKQTQNNDV---KPIFDFHQTNGHKLPDEFDLES-----YQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNV-------FDQTLPDGATIKKAPNNVWVEAIFPWIMDAE---DETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNE------TLLSTESTM-----KYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQT----------------IDTISSDYYTALSLEN-SNSPTMTYDDIGRNLNDFDTDSGITDPELATPAEIGENAAYSNYCTLAXXXXXXXXXXXXXXXLSKAKIVRAYSAHSIDELSCIPGQEVNIIDTSDVDWYKVKLSINGSTNE-GWVP-RYCIDKEETQFIRDHT--NDLMTASGYDRCLTMIGSLPVSERSQRIDDGMQ-----PGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPIS 3400
            ML N + W I++EE  +  +QF+ LNPV GFI+G QAK   TKS L   +LG+IW LAD D+DG M+ +EF+IAMHLIK+KLEG ELP+VL                                           P   +  P +  F +   +    S +  S +   A+  ++   F    P   +PQDI    PP+   TS   DWVI Q+VRPRYRLQFNQQDRNK+GFL+G EAKA+L+QSGL N+ LA IW+L+DID DG LTCEEFC+AM+LVEQAR+GR L          PS   + ++  SM              V+++ + +S   S  +   T   E R   LK              Q+ QE     A+    +    +I          EIQ Q+                        +LE EK+RL+++E+ RL+ A+ ER +E+E L ++  ++  LIDALA E+EK +  Q++++ +  ++E++KA I  MR  RD+L+D+T CL EELEAAKAE SRCQR++ NLEL+L   LQS+P    +  ++ LK  HK  I+                                 V    L++I++L++++  K+N  + IL+KQ +       K   +F +    K P    + S     Y+A+Y F GRQ DE++F+ GDII++         +GWL G L  +   GLFP +YV+KL    S E      ++T  D  QN+       F+  +    T++K+    W EAI+ W  ++     E P+QLSF  GQ I++I+    DWW GE      +  +   +GWFP+ YV+ +D  N       T+  T  ++     KYS+LN +   D+           T   S    C+A YPY+++V GDL ++PGDII+++D    WWKG+ R     G+FPS+YVK +T +DL + ++                ID +++  ++A+SL + +++P  T  D+  N       S +  P+   P  +  N A +                        A++V  ++  S +++    GQ + I + S   W+K ++   G     GW P +Y      +Q I   +  ND           T + S  +++ +  I+  ++     PGD LI MY YSAQN DELSF KN+I+ +I K+EPEWW GRN+ +S  GLFPVNYVRR Q   ++D+E + +     S    N    V GRP+S
Sbjct:    1 MLNNPNLWFITSEEKVKFDVQFQCLNPVNGFITGNQAKSLFTKSNLPTDVLGRIWFLADYDKDGCMNSNEFAIAMHLIKRKLEGYELPDVLPLSLNPLQTNATTMSYSGYMPVSNTYNTMPVMHNTSHAMSNNNPNNTMAVPHASAFVNYSTSSTMKSFST-SLSTSNAQFGSNNIPFPINNPSYAVPQDINK--PPIHTVTS-DDDWVIPQSVRPRYRLQFNQQDRNKRGFLTGVEAKAILVQSGLPNTSLASIWSLADIDQDGNLTCEEFCIAMHLVEQARSGRQLPNQLPQSLLPPSLQKKNILGTSMSASMNIPINPITNGVSVTKSIQSEKESQQKSVLTGEDERRANYLKGQAELEKRRAILDEQMRQEEEGRKAKERAEIERLEKIRQEKEQARFAEIQRQMEIRRQQELEREEQLRRVAEEREKMRLESEKKRLLEMEKRRLEVAISERRQEQESLSEVNSKKGNLIDALANEKEKKRDLQSRIESTQITLETYKAGIGSMREHRDKLIDTTDCLREELEAAKAELSRCQREKQNLELQLQSNLQSDPVLEQIKTVQALKSSHKDKIN---------------------------QRFRKEVTSKLLSDIKKLQTSVCEKKNAAIAILKKQKEPKTAVSEKNYNEFDKIGISKNPQLNSMPSNELVYYEAIYAFEGRQHDEISFKTGDIIIINTQDQIEPSSGWLYGWLDNSSHCGLFPEIYVRKLSGPPSTE-----STQTKIDVNQNISSGFADLFNNDITPKGTLRKSSECQWAEAIYHWKPESNVTYGEYPNQLSFETGQLIKIIDTNLDDWWTGETTALDANGKEKIIMGWFPKTYVRLLDEQNANHPDSGTVTPTAGSLEDLASKYSSLNLSVKYDL----------NTFDGSQKLLCVARYPYQASVLGDLNIQPGDIIEVLDQKQDWWKGYNRNTNSQGLFPSNYVKIVTSEDLANTESAKFAEGVPVEEMSESIIDLMNASQHSAISLNSVTSNPYSTISDVENN-------SALYYPQNTVP--VNSNGASTPEI---------------------AQVVIEFNPLSAEQIPLQVGQLIQIREKSPSGWWKGEIQQRGQQRRIGWFPGQYVSIINSSQSIVSDSMYNDGSLTPPTCTTPTPMSSW-INQDTSSINSTIELNDSLPGDHLITMYNYSAQNVDELSFDKNAILVLIDKNEPEWWMGRNLLSSQEGLFPVNYVRRLQAGNASDEEAMKEVAVASSQYNVN----VAGRPVS 1195          

Query: 3911 VENILKNTEDVHPDLGDMEEAVAAARSLCEAVNEGIREKENSERLEWIQDHVQCDGLNEKLYFNSTTNSLGHRKLIYSGTLYKAKSGKELVGFLFNDFLLLVTPSYNTNGYPFVFPLETSSSCKMQFKMYKKPILLNRVLIMAGSPSNQNCSLSITASTGVFGNFSHSEIFTIKEAGHDFVLKALSVNDRDKWVERLVAASLQYIETENSVREISMSIRRSAGVGRLLVTVLEGANLKSSSTPETKTHA-YCEASLGNQIRRTKVVSSTYNPKWNCHMQFLIKNIELDVLCLSAYDKEYFAPN 4816
             E ILK+TED HPD  DMEEAVAAARSLCE+VNEG+RE+ENSERLEW+Q+H+QC+ L+EKLYFNS TN LGHRKLI+SGTL K KSGKELVGFLFNDF LL TP YNT G PFVFPLETSS  KMQFKMYKKPI+LN+V+I +GSP           ++     FS ++IFT+KE   + +L+ALS NDRDKWVERL+ AS+ YI TEN  RE SMSIRR+AGVGRLLVTV+EG +L+SSS+ +      +CEASLGNQ+ RTKVV ST NPKWN  MQFLIKNI+ DVLCL+ Y+K+YFAPN
Sbjct: 1090 TEKILKHTEDNHPDRSDMEEAVAAARSLCESVNEGVRERENSERLEWLQEHMQCENLSEKLYFNSNTNCLGHRKLIHSGTLSKYKSGKELVGFLFNDFFLLATPCYNTGGMPFVFPLETSSKDKMQFKMYKKPIILNQVMISSGSP-----------TSSANSQFSSNDIFTVKEPTCEHILRALSQNDRDKWVERLMNASMFYINTENLKRECSMSIRRTAGVGRLLVTVVEGISLRSSSSHKDSKSDPFCEASLGNQLHRTKVVPSTLNPKWNTQMQFLIKNIDQDVLCLTVYNKDYFAPN 1381          

Query:   68 MLGNQSQWSISTEEFSQHRIQFEHLNPVKGFISGLQAKEYLTKSKLSNQILGKIWSLADVDQDGRMSLHEFSIAMHLIKKKLEGIELPNVL-------------------------------------------PKEMLVPPDSFPFSDLGANEIFSSKAAPSYNEVMAKDKADRQSFREKPP---IPQDIQSTFPPLPKRTSPQTDWVIMQAVRPRYRLQFNQQDRNKKGFLSGDEAKAVLLQSGLSNSILAQIWNLSDIDSDGKLTCEEFCVAMYLVEQARAGRALPSKLPETLVPPSM------------------------VTISNNNKSLPNSHTEHEWTATSESRPGTLKA--------CPASPQIIQETSMNTAQWNKPLPVTPEI----------EIQSQI----HQKLEK------------------EKQRLIDLEETRLQQAVXXXXXXXXXXXXXXDRQEFLIDALAMEEEKCQMYQAKLKESLQSVESHKAHIELMRNERDELVDSTSCLFEELEAAKAEHSRCQRDRXXXXXXXXXXXXXXPFQNDLLQLENLKQLHKQSISNLHQEIIDLQASIDLKSQNVVRNSNKLHNLENAVNCHQLAEIRRLRSNIQSKRNEVMEILEKQTQNNDV---KPIFDFHQTNGHKLPDEFDLES-----YQALYKFCGRQTDELTFEAGDIILVRNPSPANTPAGWLCGRLKINQFFGLFPNMYVKKLDPVQSNELVLTPDSETSTDKEQNV-------FDQTLPDGATIKKAPNNVWVE---------------AIFPWIMDAEDETPDQLSFNVGQRIRVIEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQPVDYSNETLLSTES 2278
            ML N + W I++EE  +  +QF+ LNPV GFI+G QAK   TKS L   +LG+IW LAD D+DG M+ +EF+IAMHLIK+KLEG ELP+VL                                           P   +  P +  F +   +    S +  S +   A+  ++   F    P   +PQDI    PP+   TS   DWVI Q+VRPRYRLQFNQQDRNK+GFL+G EAKA+L+QSGL N+ LA IW+L+DID DG LTCEEFC+AM+LVEQAR+GR LP++LP++L+PPS+                        V+++ + +S   S  +   T   E R   LK              Q+ QE     A+    +    +I          EIQ Q+     Q+LE+                  EK+RL+++E+ RL+ A+ ER +E+E L ++  ++  LIDALA E+EK +  Q++++ +  ++E++KA I  MR  RD+L+D+T CL EELEAAKAE SRCQR++ NLEL+L   LQS+P    +  ++ LK  HK  I+                                 V    L++I++L++++  K+N  + IL+KQ +       K   +F +    K P    + S     Y+A+Y F GRQ DE++F+ GDII++         +GWL G L  +   GLFP +YV+KL    S E      ++T  D  QN+       F+  +    T++ +  N+ V+               A +P+    +      L+   G  I V+++K  DWWKG        + +  S G FP  YV+ V  ++E L +TES
Sbjct:    1 MLNNPNLWFITSEEKVKFDVQFQCLNPVNGFITGNQAKSLFTKSNLPTDVLGRIWFLADYDKDGCMNSNEFAIAMHLIKRKLEGYELPDVLPLSLNPLQTNATTMSYSGYMPVSNTYNTMPVMHNTSHAMSNNNPNNTMAVPHASAFVNYSTSSTMKSFST-SLSTSNAQFGSNNIPFPINNPSYAVPQDINK--PPIHTVTS-DDDWVIPQSVRPRYRLQFNQQDRNKRGFLTGVEAKAILVQSGLPNTSLASIWSLADIDQDGNLTCEEFCIAMHLVEQARSGRQLPNQLPQSLLPPSLQKKNILGTSMSASMNIPINPITNGVSVTKSIQSEKESQQKSVLTGEDERRANYLKGQAELEKRRAILDEQMRQEEEGRKAKERAEIERLEKIRQEKEQARFAEIQRQMEIRRQQELEREEQLRRVAEEREKMRLESEKKRLLEMEKRRLEVAISERRQEQESLSEVNSKKGNLIDALANEKEKKRDLQSRIESTQITLETYKAGIGSMREHRDKLIDTTDCLREELEAAKAELSRCQREKQNLELQLQSNLQSDPVLEQIKTVQALKSSHKDKIN---------------------------QRFRKEVTSKLLSDIKKLQTSVCEKKNAAIAILKKQKEPKTAVSEKNYNEFDKIGISKNPQLNSMPSNELVYYEAIYAFEGRQHDEISFKTGDIIIINTQDQIEPSSGWLYGWLDNSSHCGLFPEIYVRKLSGPPSTE-----STQTKIDVNQNISSGFADLFNNDITPKGTLRNSSLNLSVKYDLNTFDGSQKLLCVARYPY----QASVLGDLNIQPGDIIEVLDQKQ-DWWKGY-------NRNTNSQGLFPSNYVKIV--TSEDLANTES 827          

Query: 3119 PGDKLIAMYPYSAQNPDELSFTKNSIVEIISKDEPEWWRGRNIATSMIGLFPVNYVRRPQTNCSADDEIISQSYRNPSDELNNAYSTVVGRPISWYIDGVVNFNAILTEDEKRRQFYIRELIETEK 3496
            PGD LI MY YSAQN DELSF KN+I+ +I K+EPEWW GRN+ +S  GLFPVNYVRR Q   ++D+E + +     S    N    V GRP+SWY+DG + FNAILTEDEKRRQFYIRELIETEK
Sbjct:  971 PGDHLITMYNYSAQNVDELSFDKNAILVLIDKNEPEWWMGRNLLSSQEGLFPVNYVRRLQAGNASDEEAMKEVAVASSQYNVN----VAGRPVSWYVDGTMTFNAILTEDEKRRQFYIRELIETEK 1092          

Query: 1967 TDKEQNVFDQT-LPDGATIKKAPNN--VWVEAIFPWIMDAEDETPDQLSFNVGQRIRV-----IEEKSGDWWKGEMCTHTEDDGDIYSVGWFPRIYVQ-----PVDYSNETLL------------------STESTMKYSNLNFAASNDIFGAPIXXXXXXXXXXXXGEYCLALYPYESTVPGDLTMRPGDIIQIVDMSTHWWKGHIRGARENGMFPSHYVKKLTKQDLEHAQT----------------IDTISSDYYTALSLEN-SNSPTMTYDDIGRN------LNDFDTDS-GITDPELA 2713
            ++K  N FD+  +     +   P+N  V+ EAI+ +    E    D++SF  G  I +     IE  SG W  G +   +         G FP IYV+     P   S +T +                  + + T++ S+LN +   D+           T   S    C+A YPY+++V GDL ++PGDII+++D    WWKG+ R     G+FPS+YVK +T +DL + ++                ID +++  ++A+SL + +++P  T  D+  N       N    +S G + PE+A
Sbjct:  616 SEKNYNEFDKIGISKNPQLNSMPSNELVYYEAIYAF----EGRQHDEISFKTGDIIIINTQDQIEPSSG-WLYGWLDNSSH-------CGLFPEIYVRKLSGPPSTESTQTKIDVNQNISSGFADLFNNDITPKGTLRNSSLNLSVKYDL----------NTFDGSQKLLCVARYPYQASVLGDLNIQPGDIIEVLDQKQDWWKGYNRNTNSQGLFPSNYVKIVTSEDLANTESAKFAEGVPVEEMSESIIDLMNASQHSAISLNSVTSNPYSTISDVENNSALYYPQNTVPVNSNGASTPEIA 897