Leucine-rich repeat-containing protein 57
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny AppSub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30020334 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 5
Homology
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Human
Match: MFHAS1 (malignant fibrous histiocytoma amplified sequence 1 [Source:HGNC Symbol;Acc:HGNC:16982]) HSP 1 Score: 113.235 bits (282), Expect = 1.292e-26 Identity = 81/243 (33.33%), Postives = 117/243 (48.15%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLD-WSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFKKMYGSSVVEVPAAK 844
++ L + L++ P +L L+ LE LD+S R GL P I L LKIL L +L +P L +LE + L NN L LP + L++L+ L++++N FE FP + + +E S N SVP I L L TL L N++ LPD + EL + L L N++ LP FG+L + W + NPL PP ++C KG I Y K++ S P K
Sbjct: 183 LRTLDVDHNQLTAFPRQLLQLVALEELDVSSNRLRGL-------PEDISALRALKILWLSGAELGTLPAGFCELASLESLMLDNNGLQALPAQFSCLQRLKMLNLSSNLFEEFPAALLPLAGLEELYLSRNQLTSVPSLISGLGRLLTLWLDNNRIRYLPDSIVELTGLEELVLQGNQIAVLPDHFGQLSRVGLWK-------IKDNPLIQPPYEVCMKGIPYIAAYQKELAHSQPAVQPRLK 411 HSP 2 Score: 97.0561 bits (240), Expect = 3.516e-21 Identity = 65/199 (32.66%), Postives = 104/199 (52.26%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNL-LDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFG---RLKLLDWS 703
++ L L+ + +PP + L L LD+S R L ++ + L L+ L L N L +P ++G L +LE + +S N L LP+ + L +LR+L + +N+ FP + +++++E D S N R +P+ I L++L+ L L +L LP CEL + L L NN L LP QF RLK+L+ S
Sbjct: 89 LRVLVLRRNRFARLPPAVAELGHHLTELDVSHNRLTALGAEV------VSALRELRKLNLSHNQLPALPAQLGALAHLEELDVSFNRLAHLPDSLSCLSRLRTLDVDHNQLTAFPRQLLQLVALEELDVSSNRLRGLPEDISALRALKILWLSGAELGTLPAGFCELASLESLMLDNNGLQALPAQFSCLQRLKMLNLS 281
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Human
Match: MFHAS1 (malignant fibrous histiocytoma amplified sequence 1 [Source:HGNC Symbol;Acc:HGNC:16982]) HSP 1 Score: 113.235 bits (282), Expect = 1.292e-26 Identity = 81/243 (33.33%), Postives = 117/243 (48.15%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLD-WSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFKKMYGSSVVEVPAAK 844
++ L + L++ P +L L+ LE LD+S R GL P I L LKIL L +L +P L +LE + L NN L LP + L++L+ L++++N FE FP + + +E S N SVP I L L TL L N++ LPD + EL + L L N++ LP FG+L + W + NPL PP ++C KG I Y K++ S P K
Sbjct: 183 LRTLDVDHNQLTAFPRQLLQLVALEELDVSSNRLRGL-------PEDISALRALKILWLSGAELGTLPAGFCELASLESLMLDNNGLQALPAQFSCLQRLKMLNLSSNLFEEFPAALLPLAGLEELYLSRNQLTSVPSLISGLGRLLTLWLDNNRIRYLPDSIVELTGLEELVLQGNQIAVLPDHFGQLSRVGLWK-------IKDNPLIQPPYEVCMKGIPYIAAYQKELAHSQPAVQPRLK 411 HSP 2 Score: 97.0561 bits (240), Expect = 3.516e-21 Identity = 65/199 (32.66%), Postives = 104/199 (52.26%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNL-LDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFG---RLKLLDWS 703
++ L L+ + +PP + L L LD+S R L ++ + L L+ L L N L +P ++G L +LE + +S N L LP+ + L +LR+L + +N+ FP + +++++E D S N R +P+ I L++L+ L L +L LP CEL + L L NN L LP QF RLK+L+ S
Sbjct: 89 LRVLVLRRNRFARLPPAVAELGHHLTELDVSHNRLTALGAEV------VSALRELRKLNLSHNQLPALPAQLGALAHLEELDVSFNRLAHLPDSLSCLSRLRTLDVDHNQLTAFPRQLLQLVALEELDVSSNRLRGLPEDISALRALKILWLSGAELGTLPAGFCELASLESLMLDNNGLQALPAQFSCLQRLKMLNLS 281
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Human
Match: MFHAS1 (malignant fibrous histiocytoma amplified sequence 1 [Source:HGNC Symbol;Acc:HGNC:16982]) HSP 1 Score: 112.849 bits (281), Expect = 1.725e-26 Identity = 81/243 (33.33%), Postives = 117/243 (48.15%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLD-WSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFKKMYGSSVVEVPAAK 844
++ L + L++ P +L L+ LE LD+S R GL P I L LKIL L +L +P L +LE + L NN L LP + L++L+ L++++N FE FP + + +E S N SVP I L L TL L N++ LPD + EL + L L N++ LP FG+L + W + NPL PP ++C KG I Y K++ S P K
Sbjct: 183 LRTLDVDHNQLTAFPRQLLQLVALEELDVSSNRLRGL-------PEDISALRALKILWLSGAELGTLPAGFCELASLESLMLDNNGLQALPAQFSCLQRLKMLNLSSNLFEEFPAALLPLAGLEELYLSRNQLTSVPSLISGLGRLLTLWLDNNRIRYLPDSIVELTGLEELVLQGNQIAVLPDHFGQLSRVGLWK-------IKDNPLIQPPYEVCMKGIPYIAAYQKELAHSQPAVQPRLK 411 HSP 2 Score: 96.6709 bits (239), Expect = 4.553e-21 Identity = 65/199 (32.66%), Postives = 104/199 (52.26%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNL-LDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFG---RLKLLDWS 703
++ L L+ + +PP + L L LD+S R L ++ + L L+ L L N L +P ++G L +LE + +S N L LP+ + L +LR+L + +N+ FP + +++++E D S N R +P+ I L++L+ L L +L LP CEL + L L NN L LP QF RLK+L+ S
Sbjct: 89 LRVLVLRRNRFARLPPAVAELGHHLTELDVSHNRLTALGAEV------VSALRELRKLNLSHNQLPALPAQLGALAHLEELDVSFNRLAHLPDSLSCLSRLRTLDVDHNQLTAFPRQLLQLVALEELDVSSNRLRGLPEDISALRALKILWLSGAELGTLPAGFCELASLESLMLDNNGLQALPAQFSCLQRLKMLNLS 281
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Human
Match: LRCH3 (leucine rich repeats and calponin homology domain containing 3 [Source:HGNC Symbol;Acc:HGNC:28637]) HSP 1 Score: 102.449 bits (254), Expect = 3.956e-23 Identity = 80/226 (35.40%), Postives = 113/226 (50.00%), Query Frame = 2
Query: 128 LKLQGKDLSSVPPELFN--LLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYF 799
L L G+ L P N L D D+S R L E+P+ ++L+ L L N +R++P+ I L L + +S N L+TLP + NL L+ L +NNK + PE I + + D S N +++P I NL++L L + N L LP+EL EL +R L NK+T +P + L+ H + TLD NPLQ PP IC KG I KY
Sbjct: 62 LSLSGRKLREFPRGAANHDLTDTTRADLSRNR-------LSEIPIEACHFVSLENLNLYQNCIRYIPEAILNLQALTFLNISRNQLSTLPVHLCNLP-LKVLIASNNKLVSLPEEIGHLRHLMELDVSCNEIQTIPSQIGNLEALRDLNVRRNHLVHLPEELAELPLIR-LDFSCNKITTIPVCYRNLR------HLQTITLDNNPLQSPPAQICIKGKVHIFKYL 272 HSP 2 Score: 75.8702 bits (185), Expect = 2.831e-14 Identity = 52/167 (31.14%), Postives = 86/167 (51.50%), Query Frame = 2
Query: 110 FYGMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELC 610
F ++ L L + +P + NL L L++S + + L L +PL K+L+ N L +P+EIG L +L + +S N + T+P++I NL+ LR L++ N PE + E L + D S N ++P RNL+ L+T+ L N L+ P ++C
Sbjct: 104 FVSLENLNLYQNCIRYIPEAILNLQALTFLNISRNQLSTLPVHLCNLPL--------KVLIASNNKLVSLPEEIGHLRHLMELDVSCNEIQTIPSQIGNLEALRDLNVRRNHLVHLPEELAE-LPLIRLDFSCNKITTIPVCYRNLRHLQTITLDNNPLQSPPAQIC 261
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Human
Match: LRCH3 (leucine rich repeats and calponin homology domain containing 3 [Source:HGNC Symbol;Acc:HGNC:28637]) HSP 1 Score: 102.449 bits (254), Expect = 3.956e-23 Identity = 80/226 (35.40%), Postives = 113/226 (50.00%), Query Frame = 2
Query: 128 LKLQGKDLSSVPPELFN--LLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYF 799
L L G+ L P N L D D+S R L E+P+ ++L+ L L N +R++P+ I L L + +S N L+TLP + NL L+ L +NNK + PE I + + D S N +++P I NL++L L + N L LP+EL EL +R L NK+T +P + L+ H + TLD NPLQ PP IC KG I KY
Sbjct: 62 LSLSGRKLREFPRGAANHDLTDTTRADLSRNR-------LSEIPIEACHFVSLENLNLYQNCIRYIPEAILNLQALTFLNISRNQLSTLPVHLCNLP-LKVLIASNNKLVSLPEEIGHLRHLMELDVSCNEIQTIPSQIGNLEALRDLNVRRNHLVHLPEELAELPLIR-LDFSCNKITTIPVCYRNLR------HLQTITLDNNPLQSPPAQICIKGKVHIFKYL 272 HSP 2 Score: 75.8702 bits (185), Expect = 2.831e-14 Identity = 52/167 (31.14%), Postives = 86/167 (51.50%), Query Frame = 2
Query: 110 FYGMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELC 610
F ++ L L + +P + NL L L++S + + L L +PL K+L+ N L +P+EIG L +L + +S N + T+P++I NL+ LR L++ N PE + E L + D S N ++P RNL+ L+T+ L N L+ P ++C
Sbjct: 104 FVSLENLNLYQNCIRYIPEAILNLQALTFLNISRNQLSTLPVHLCNLPL--------KVLIASNNKLVSLPEEIGHLRHLMELDVSCNEIQTIPSQIGNLEALRDLNVRRNHLVHLPEELAE-LPLIRLDFSCNKITTIPVCYRNLRHLQTITLDNNPLQSPPAQIC 261
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Celegans
Match: let-413 (pep chromosome:WBcel235:V:7972934:7977774:-1 gene:WBGene00002632.1 transcript:F26D11.11b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:let-413) HSP 1 Score: 97.0561 bits (240), Expect = 1.090e-21 Identity = 66/209 (31.58%), Postives = 109/209 (52.15%), Query Frame = 2
Query: 143 KDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICE-----ILS------------------MEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDW 700
+L ++P ++F LE L+++ ++E+ + L +L+IL + N+L +P EIG LT L + L+ NS+ LP+ ++N K L +L++++N F PE ICE ILS + +A DN+ R++P SI L+ LE L L +N+LE LP E+ +L +R ++ N LT LP ++LD
Sbjct: 23 SNLQAIPSDIFRFRKLEDLNLT-------MNNIKELDHRLFSLRHLRILDVSDNELAVLPAEIGNLTQLIELNLNRNSIAKLPDTMQNCKLLTTLNLSSNPFTRLPETICECSSITILSLNETSLTLLPSNIGSLTNLRVLEARDNLLRTIPLSIVELRKLEELDLGQNELEALPAEIGKLTSLREFYVDINSLTSLPDSISGCRMLDQ 224 HSP 2 Score: 78.1814 bits (191), Expect = 1.592e-15 Identity = 69/217 (31.80%), Postives = 103/217 (47.47%), Query Frame = 2
Query: 128 LKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDI--CKK 772
L L L+ +P + +L +L VL+ L+ +PLSI +L L+ L L N+L +P EIG LT+L + NSLT+LP+ I + L L ++ N+ PE + + ++ + S N +P S LK L+ L N L L E+ + + L+LG N LT LP G L+ L T+ +D N L P I CK
Sbjct: 133 LSLNETSLTLLPSNIGSLTNLRVLEARDNL-------LRTIPLSIVELRKLEELDLGQNELEALPAEIGKLTSLREFYVDINSLTSLPDSISGCRMLDQLDVSENQIIRLPENLGRMPNLTDLNISINEIIELPSSFGELKRLQMLKADRNSLHNLTSEIGKCQSLTELYLGQNFLTDLPDTIGDLRQL------TTLNVDCNNLSDIPDTIGNCKS 336 HSP 3 Score: 77.411 bits (189), Expect = 3.030e-15 Identity = 61/208 (29.33%), Postives = 100/208 (48.08%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQ----------------EVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLL 694
++ L + +L+ +P E+ NL L L+++ A L +Q +P +I + ++ IL L+ L +P IG LTNL + +N L T+P I L+KL L + N+ E P I ++ S+ F N S+P SI + L+ L + ENQ+ LP+ L + + L + N++ +LP FG LK L
Sbjct: 61 LRILDVSDNELAVLPAEIGNLTQLIELNLNRNSIAKLPDTMQNCKLLTTLNLSSNPFTRLPETICECSSITILSLNETSLTLLPSNIGSLTNLRVLEARDNLLRTIPLSIVELRKLEELDLGQNELEALPAEIGKLTSLREFYVDINSLTSLPDSISGCRMLDQLDVSENQIIRLPENLGRMPNLTDLNISINEIIELPSSFGELKRL 268 HSP 4 Score: 68.1662 bits (165), Expect = 3.179e-12 Identity = 43/142 (30.28%), Postives = 73/142 (51.41%), Query Frame = 2
Query: 245 EVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPK 670
E+P S G+L L++L D N L ++ EIG +L + L N LT LP+ I +L++L +L++ N P+ I S+ N+ +P +I ++L L + N+L LP + L +++ LWL N+ + K
Sbjct: 257 ELPSSFGELKRLQMLKADRNSLHNLTSEIGKCQSLTELYLGQNFLTDLPDTIGDLRQLTTLNVDCNNLSDIPDTIGNCKSLTVLSLRQNILTELPMTIGKCENLTVLDVASNKLPHLPFTVKVLYKLQALWLSENQTQSILK 398 HSP 5 Score: 63.5438 bits (153), Expect = 1.008e-10 Identity = 50/186 (26.88%), Postives = 85/186 (45.70%), Query Frame = 2
Query: 149 LSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSW 706
L+S+P + L+ LD+S ++ +P ++G++ NL L + N++ +P G L L+ + NSL L +EI + L L++ N P+ I ++ + + N +P +I N KSL L L +N L LP + + + L + +NKL LP L L W
Sbjct: 209 LTSLPDSISGCRMLDQLDVSEN-------QIIRLPENLGRMPNLTDLNISINEIIELPSSFGELKRLQMLKADRNSLHNLTSEIGKCQSLTELYLGQNFLTDLPDTIGDLRQLTTLNVDCNNLSDIPDTIGNCKSLTVLSLRQNILTELPMTIGKCENLTVLDVASNKLPHLPFTVKVLYKLQALW 387 HSP 6 Score: 61.2326 bits (147), Expect = 5.815e-10 Identity = 63/237 (26.58%), Postives = 101/237 (42.62%), Query Frame = 2
Query: 134 LQGKD--LSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCL------------WLGN-----------NKLTQLPKQFGRLKLLDWSWHYTSTTLD--GNPLQHPPLDI 763
L+ +D L ++P + L LE LD+ +L+ +P IGKL +L+ +D N L +P I L+++ +S N + LP + + L L+I+ N+ P E+ ++ A N ++ I +SL L L +N L LPD + +L Q+ L +GN N LT+LP G+ + L T LD N L H P +
Sbjct: 156 LEARDNLLRTIPLSIVELRKLEELDLG-------QNELEALPAEIGKLTSLREFYVDINSLTSLPDSISGCRMLDQLDVSENQIIRLPENLGRMPNLTDLNISINEIIELPSSFGELKRLQMLKADRNSLHNLTSEIGKCQSLTELYLGQNFLTDLPDTIGDLRQLTTLNVDCNNLSDIPDTIGNCKSLTVLSLRQNILTELPMTIGKCENL--------TVLDVASNKLPHLPFTV 377
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Celegans
Match: let-413 (pep chromosome:WBcel235:V:7972924:7977774:-1 gene:WBGene00002632.1 transcript:F26D11.11a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:let-413) HSP 1 Score: 96.6709 bits (239), Expect = 1.275e-21 Identity = 66/208 (31.73%), Postives = 109/208 (52.40%), Query Frame = 2
Query: 146 DLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICE-----ILS------------------MEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDW 700
+L ++P ++F LE L+++ ++E+ + L +L+IL + N+L +P EIG LT L + L+ NS+ LP+ ++N K L +L++++N F PE ICE ILS + +A DN+ R++P SI L+ LE L L +N+LE LP E+ +L +R ++ N LT LP ++LD
Sbjct: 24 NLQAIPSDIFRFRKLEDLNLT-------MNNIKELDHRLFSLRHLRILDVSDNELAVLPAEIGNLTQLIELNLNRNSIAKLPDTMQNCKLLTTLNLSSNPFTRLPETICECSSITILSLNETSLTLLPSNIGSLTNLRVLEARDNLLRTIPLSIVELRKLEELDLGQNELEALPAEIGKLTSLREFYVDINSLTSLPDSISGCRMLDQ 224 HSP 2 Score: 78.1814 bits (191), Expect = 1.966e-15 Identity = 69/216 (31.94%), Postives = 103/216 (47.69%), Query Frame = 2
Query: 128 LKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDI--CK 769
L L L+ +P + +L +L VL+ L+ +PLSI +L L+ L L N+L +P EIG LT+L + NSLT+LP+ I + L L ++ N+ PE + + ++ + S N +P S LK L+ L N L L E+ + + L+LG N LT LP G L+ L T+ +D N L P I CK
Sbjct: 133 LSLNETSLTLLPSNIGSLTNLRVLEARDNL-------LRTIPLSIVELRKLEELDLGQNELEALPAEIGKLTSLREFYVDINSLTSLPDSISGCRMLDQLDVSENQIIRLPENLGRMPNLTDLNISINEIIELPSSFGELKRLQMLKADRNSLHNLTSEIGKCQSLTELYLGQNFLTDLPDTIGDLRQL------TTLNVDCNNLSDIPDTIGNCK 335 HSP 3 Score: 77.411 bits (189), Expect = 3.386e-15 Identity = 61/208 (29.33%), Postives = 100/208 (48.08%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQ----------------EVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLL 694
++ L + +L+ +P E+ NL L L+++ A L +Q +P +I + ++ IL L+ L +P IG LTNL + +N L T+P I L+KL L + N+ E P I ++ S+ F N S+P SI + L+ L + ENQ+ LP+ L + + L + N++ +LP FG LK L
Sbjct: 61 LRILDVSDNELAVLPAEIGNLTQLIELNLNRNSIAKLPDTMQNCKLLTTLNLSSNPFTRLPETICECSSITILSLNETSLTLLPSNIGSLTNLRVLEARDNLLRTIPLSIVELRKLEELDLGQNELEALPAEIGKLTSLREFYVDINSLTSLPDSISGCRMLDQLDVSENQIIRLPENLGRMPNLTDLNISINEIIELPSSFGELKRL 268 HSP 4 Score: 67.781 bits (164), Expect = 3.683e-12 Identity = 43/142 (30.28%), Postives = 73/142 (51.41%), Query Frame = 2
Query: 245 EVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPK 670
E+P S G+L L++L D N L ++ EIG +L + L N LT LP+ I +L++L +L++ N P+ I S+ N+ +P +I ++L L + N+L LP + L +++ LWL N+ + K
Sbjct: 257 ELPSSFGELKRLQMLKADRNSLHNLTSEIGKCQSLTELYLGQNFLTDLPDTIGDLRQLTTLNVDCNNLSDIPDTIGNCKSLTVLSLRQNILTELPMTIGKCENLTVLDVASNKLPHLPFTVKVLYKLQALWLSENQTQSILK 398 HSP 5 Score: 63.1586 bits (152), Expect = 1.117e-10 Identity = 50/186 (26.88%), Postives = 85/186 (45.70%), Query Frame = 2
Query: 149 LSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSW 706
L+S+P + L+ LD+S ++ +P ++G++ NL L + N++ +P G L L+ + NSL L +EI + L L++ N P+ I ++ + + N +P +I N KSL L L +N L LP + + + L + +NKL LP L L W
Sbjct: 209 LTSLPDSISGCRMLDQLDVSEN-------QIIRLPENLGRMPNLTDLNISINEIIELPSSFGELKRLQMLKADRNSLHNLTSEIGKCQSLTELYLGQNFLTDLPDTIGDLRQLTTLNVDCNNLSDIPDTIGNCKSLTVLSLRQNILTELPMTIGKCENLTVLDVASNKLPHLPFTVKVLYKLQALW 387 HSP 6 Score: 60.8474 bits (146), Expect = 6.859e-10 Identity = 63/237 (26.58%), Postives = 101/237 (42.62%), Query Frame = 2
Query: 134 LQGKD--LSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCL------------WLGN-----------NKLTQLPKQFGRLKLLDWSWHYTSTTLD--GNPLQHPPLDI 763
L+ +D L ++P + L LE LD+ +L+ +P IGKL +L+ +D N L +P I L+++ +S N + LP + + L L+I+ N+ P E+ ++ A N ++ I +SL L L +N L LPD + +L Q+ L +GN N LT+LP G+ + L T LD N L H P +
Sbjct: 156 LEARDNLLRTIPLSIVELRKLEELDLG-------QNELEALPAEIGKLTSLREFYVDINSLTSLPDSISGCRMLDQLDVSENQIIRLPENLGRMPNLTDLNISINEIIELPSSFGELKRLQMLKADRNSLHNLTSEIGKCQSLTELYLGQNFLTDLPDTIGDLRQLTTLNVDCNNLSDIPDTIGNCKSLTVLSLRQNILTELPMTIGKCENL--------TVLDVASNKLPHLPFTV 377 HSP 7 Score: 56.6102 bits (135), Expect = 1.818e-8 Identity = 36/128 (28.12%), Postives = 64/128 (50.00%), Query Frame = 2
Query: 302 NDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRL 685
++L+ +P +I LE + L+ N++ L + + +L+ LR L +++N+ P I + + + + N +P +++N K L TL L N LP+ +CE + L L LT LP G L
Sbjct: 23 SNLQAIPSDIFRFRKLEDLNLTMNNIKELDHRLFSLRHLRILDVSDNELAVLPAEIGNLTQLIELNLNRNSIAKLPDTMQNCKLLTTLNLSSNPFTRLPETICECSSITILSLNETSLTLLPSNIGSL 150
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Celegans
Match: Y42G9A.3 (pep chromosome:WBcel235:III:6146214:6148065:1 gene:WBGene00021533.1 transcript:Y42G9A.3b.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y42G9A.3) HSP 1 Score: 87.0409 bits (214), Expect = 3.468e-19 Identity = 64/188 (34.04%), Postives = 92/188 (48.94%), Query Frame = 2
Query: 185 DLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQH 748
++ VLD+S + L +P IG L +L L+ N L H+PK + LL NLE + LS N L +P I ++KL++LH+ N ++ P I + + N R +P SI L LE L L +N LE +P L +L + L L NN+L LP L+ L +L NPL H
Sbjct: 84 NVSVLDVS-------FNSLSALPEDIGTLSSLTTLIARNNLLEHLPKGLQLLENLEHLYLSGNRLEYVPPVILTMRKLKTLHLGGNYIDSCPSNISVLTLLRVLYLGGNRLREIPASIGCLDELENLGLCDNILETIPSTLGDLHYLETLSLHNNRLRTLPTDILNLRRLQ------QLSLRNNPLVH 258
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Celegans
Match: Y42G9A.3 (pep chromosome:WBcel235:III:6146266:6148065:1 gene:WBGene00021533.1 transcript:Y42G9A.3b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y42G9A.3) HSP 1 Score: 87.0409 bits (214), Expect = 3.468e-19 Identity = 64/188 (34.04%), Postives = 92/188 (48.94%), Query Frame = 2
Query: 185 DLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQH 748
++ VLD+S + L +P IG L +L L+ N L H+PK + LL NLE + LS N L +P I ++KL++LH+ N ++ P I + + N R +P SI L LE L L +N LE +P L +L + L L NN+L LP L+ L +L NPL H
Sbjct: 84 NVSVLDVS-------FNSLSALPEDIGTLSSLTTLIARNNLLEHLPKGLQLLENLEHLYLSGNRLEYVPPVILTMRKLKTLHLGGNYIDSCPSNISVLTLLRVLYLGGNRLREIPASIGCLDELENLGLCDNILETIPSTLGDLHYLETLSLHNNRLRTLPTDILNLRRLQ------QLSLRNNPLVH 258
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Celegans
Match: Y42G9A.3 (pep chromosome:WBcel235:III:6146214:6148065:1 gene:WBGene00021533.1 transcript:Y42G9A.3a.3 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y42G9A.3) HSP 1 Score: 87.8113 bits (216), Expect = 4.288e-19 Identity = 64/188 (34.04%), Postives = 92/188 (48.94%), Query Frame = 2
Query: 185 DLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQH 748
++ VLD+S + L +P IG L +L L+ N L H+PK + LL NLE + LS N L +P I ++KL++LH+ N ++ P I + + N R +P SI L LE L L +N LE +P L +L + L L NN+L LP L+ L +L NPL H
Sbjct: 84 NVSVLDVS-------FNSLSALPEDIGTLSSLTTLIARNNLLEHLPKGLQLLENLEHLYLSGNRLEYVPPVILTMRKLKTLHLGGNYIDSCPSNISVLTLLRVLYLGGNRLREIPASIGCLDELENLGLCDNILETIPSTLGDLHYLETLSLHNNRLRTLPTDILNLRRLQ------QLSLRNNPLVH 258
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Fly
Match: Lap1 (gene:FBgn0033984 transcript:FBtr0087407) HSP 1 Score: 92.8189 bits (229), Expect = 3.424e-20 Identity = 64/214 (29.91%), Postives = 104/214 (48.60%), Query Frame = 2
Query: 116 GMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLY-----------------------ENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLK 688
++ L+L+ +L ++P + L++L+ LD+ + E+P +G+L +L+ L +D N +R V IG L +L+ + N L TLP+E+ N + + L I +N E FP + + S+ F N +P SI L+ LE L+L +NQL LPDELC Q+ L + NN+L+ LP+ G L
Sbjct: 156 NLRILELRLNNLMTLPKSMVRLINLQRLDIGGN-------EFTELPEVVGELKSLRELWIDFNQIRRVSANIGKLRDLQHFEANGNLLDTLPSELSNWRNVEVLSICSNSLEAFPFSVGMLKSLVTFKCESNGLTELPDSISYLEQLEELVLSHNKLIRLPSTIGMLRSLRFLFADDNQLRQLPDELCSCQQLSVLSVANNQLSALPQNIGNLS 362 HSP 2 Score: 82.4185 bits (202), Expect = 9.822e-17 Identity = 70/257 (27.24%), Postives = 119/257 (46.30%), Query Frame = 2
Query: 68 NKSLRMMVDTEDPLFYGMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEG-----------------------LPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDICK 769
N++L + V E + L L L +P + +L+ L+ L ++ L+ +P + G+L+NL+IL L N+L +PK + L NL+R+ + N T LP + LK LR L I N+ I ++ ++ F+A+ N+ ++P + N +++E L + N LE LPD + L Q+ L L +NKL +LP G L+ L + + D N L+ P ++C
Sbjct: 94 NRNLIVNVPEEIKSCKHLTHLDLSCNSLQRLPDAITSLISLQELLLNETY-------LEFLPANFGRLVNLRILELRLNNLMTLPKSMVRLINLQRLDIGGNEFTELPEVVGELKSLRELWIDFNQIRRVSANIGKLRDLQHFEANGNLLDTLPSELSNWRNVEVLSICSNSLEAFPFSVGMLKSLVTFKCESNGLTELPDSISYLEQLEELVLSHNKLIRLPSTIGMLRSLRFLF------ADDNQLRQLPDELCS 337 HSP 3 Score: 78.9518 bits (193), Expect = 1.296e-15 Identity = 47/157 (29.94%), Postives = 84/157 (53.50%), Query Frame = 2
Query: 236 KLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSW 706
+LQ +P + L++L +++N+L +P+ IG L L+ + L+ N + +P EIK+ K L L ++ N + P+ I ++S++ ++ +P + L +L L L N L LP + LI ++ L +G N+ T+LP+ G LK L W
Sbjct: 51 RLQALPPQLFYCQGLRVLHVNSNNLESIPQAIGSLRQLQHLDLNRNLIVNVPEEIKSCKHLTHLDLSCNSLQRLPDAITSLISLQELLLNETYLEFLPANFGRLVNLRILELRLNNLMTLPKSMVRLINLQRLDIGGNEFTELPEVVGELKSLRELW 207 HSP 4 Score: 76.2554 bits (186), Expect = 1.138e-14 Identity = 55/190 (28.95%), Postives = 99/190 (52.11%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLK 688
+++L L L ++PP+LF L VL ++ L+ +P +IG L L+ L L+ N + +VP+EI +L + LS NSL LP+ I +L L+ L + E P ++++ + N ++PKS+ L +L+ L + N+ LP+ + EL +R LW+ N++ ++ G+L+
Sbjct: 42 LEELYLSTTRLQALPPQLFYCQGLRVLHVNSN-------NLESIPQAIGSLRQLQHLDLNRNLIVNVPEEIKSCKHLTHLDLSCNSLQRLPDAITSLISLQELLLNETYLEFLPANFGRLVNLRILELRLNNLMTLPKSMVRLINLQRLDIGGNEFTELPEVVGELKSLRELWIDFNQIRRVSANIGKLR 224 HSP 5 Score: 75.485 bits (184), Expect = 1.647e-14 Identity = 50/170 (29.41%), Postives = 82/170 (48.24%), Query Frame = 2
Query: 239 LQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQH 748
L +P + N+++L + +N L P +G+L +L +N LT LP+ I L++L L +++NK P I + S+ F A DN R +P + + + L L + NQL LP + L +M+ L + NN + LP L L W + + PLQ+
Sbjct: 236 LDTLPSELSNWRNVEVLSICSNSLEAFPFSVGMLKSLVTFKCESNGLTELPDSISYLEQLEELVLSHNKLIRLPSTIGMLRSLRFLFADDNQLRQLPDELCSCQQLSVLSVANNQLSALPQNIGNLSKMKVLNVVNNYINALPVSMLNLVNLTSMWLSDNQSQPLVPLQY 405 HSP 6 Score: 61.2326 bits (147), Expect = 7.130e-10 Identity = 43/140 (30.71%), Postives = 69/140 (49.29%), Query Frame = 2
Query: 104 PLFYGMKK----LKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDN 511
P GM K K + L+ +P + L LE L +S + KL +P +IG L +L+ L D N LR +P E+ L ++++NN L+ LP I NL K++ L++ NN P + ++++ SDN
Sbjct: 263 PFSVGMLKSLVTFKCESNGLTELPDSISYLEQLEELVLS-------HNKLIRLPSTIGMLRSLRFLFADDNQLRQLPDELCSCQQLSVLSVANNQLSALPQNIGNLSKMKVLNVVNNYINALPVSMLNLVNLTSMWLSDN 395
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Fly
Match: Lap1 (gene:FBgn0033984 transcript:FBtr0303759) HSP 1 Score: 92.8189 bits (229), Expect = 3.424e-20 Identity = 64/214 (29.91%), Postives = 104/214 (48.60%), Query Frame = 2
Query: 116 GMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLY-----------------------ENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLK 688
++ L+L+ +L ++P + L++L+ LD+ + E+P +G+L +L+ L +D N +R V IG L +L+ + N L TLP+E+ N + + L I +N E FP + + S+ F N +P SI L+ LE L+L +NQL LPDELC Q+ L + NN+L+ LP+ G L
Sbjct: 156 NLRILELRLNNLMTLPKSMVRLINLQRLDIGGN-------EFTELPEVVGELKSLRELWIDFNQIRRVSANIGKLRDLQHFEANGNLLDTLPSELSNWRNVEVLSICSNSLEAFPFSVGMLKSLVTFKCESNGLTELPDSISYLEQLEELVLSHNKLIRLPSTIGMLRSLRFLFADDNQLRQLPDELCSCQQLSVLSVANNQLSALPQNIGNLS 362 HSP 2 Score: 82.4185 bits (202), Expect = 9.822e-17 Identity = 70/257 (27.24%), Postives = 119/257 (46.30%), Query Frame = 2
Query: 68 NKSLRMMVDTEDPLFYGMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEG-----------------------LPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDICK 769
N++L + V E + L L L +P + +L+ L+ L ++ L+ +P + G+L+NL+IL L N+L +PK + L NL+R+ + N T LP + LK LR L I N+ I ++ ++ F+A+ N+ ++P + N +++E L + N LE LPD + L Q+ L L +NKL +LP G L+ L + + D N L+ P ++C
Sbjct: 94 NRNLIVNVPEEIKSCKHLTHLDLSCNSLQRLPDAITSLISLQELLLNETY-------LEFLPANFGRLVNLRILELRLNNLMTLPKSMVRLINLQRLDIGGNEFTELPEVVGELKSLRELWIDFNQIRRVSANIGKLRDLQHFEANGNLLDTLPSELSNWRNVEVLSICSNSLEAFPFSVGMLKSLVTFKCESNGLTELPDSISYLEQLEELVLSHNKLIRLPSTIGMLRSLRFLF------ADDNQLRQLPDELCS 337 HSP 3 Score: 78.9518 bits (193), Expect = 1.296e-15 Identity = 47/157 (29.94%), Postives = 84/157 (53.50%), Query Frame = 2
Query: 236 KLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSW 706
+LQ +P + L++L +++N+L +P+ IG L L+ + L+ N + +P EIK+ K L L ++ N + P+ I ++S++ ++ +P + L +L L L N L LP + LI ++ L +G N+ T+LP+ G LK L W
Sbjct: 51 RLQALPPQLFYCQGLRVLHVNSNNLESIPQAIGSLRQLQHLDLNRNLIVNVPEEIKSCKHLTHLDLSCNSLQRLPDAITSLISLQELLLNETYLEFLPANFGRLVNLRILELRLNNLMTLPKSMVRLINLQRLDIGGNEFTELPEVVGELKSLRELW 207 HSP 4 Score: 76.2554 bits (186), Expect = 1.138e-14 Identity = 55/190 (28.95%), Postives = 99/190 (52.11%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLK 688
+++L L L ++PP+LF L VL ++ L+ +P +IG L L+ L L+ N + +VP+EI +L + LS NSL LP+ I +L L+ L + E P ++++ + N ++PKS+ L +L+ L + N+ LP+ + EL +R LW+ N++ ++ G+L+
Sbjct: 42 LEELYLSTTRLQALPPQLFYCQGLRVLHVNSN-------NLESIPQAIGSLRQLQHLDLNRNLIVNVPEEIKSCKHLTHLDLSCNSLQRLPDAITSLISLQELLLNETYLEFLPANFGRLVNLRILELRLNNLMTLPKSMVRLINLQRLDIGGNEFTELPEVVGELKSLRELWIDFNQIRRVSANIGKLR 224 HSP 5 Score: 75.485 bits (184), Expect = 1.647e-14 Identity = 50/170 (29.41%), Postives = 82/170 (48.24%), Query Frame = 2
Query: 239 LQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQH 748
L +P + N+++L + +N L P +G+L +L +N LT LP+ I L++L L +++NK P I + S+ F A DN R +P + + + L L + NQL LP + L +M+ L + NN + LP L L W + + PLQ+
Sbjct: 236 LDTLPSELSNWRNVEVLSICSNSLEAFPFSVGMLKSLVTFKCESNGLTELPDSISYLEQLEELVLSHNKLIRLPSTIGMLRSLRFLFADDNQLRQLPDELCSCQQLSVLSVANNQLSALPQNIGNLSKMKVLNVVNNYINALPVSMLNLVNLTSMWLSDNQSQPLVPLQY 405 HSP 6 Score: 61.2326 bits (147), Expect = 7.130e-10 Identity = 43/140 (30.71%), Postives = 69/140 (49.29%), Query Frame = 2
Query: 104 PLFYGMKK----LKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDN 511
P GM K K + L+ +P + L LE L +S + KL +P +IG L +L+ L D N LR +P E+ L ++++NN L+ LP I NL K++ L++ NN P + ++++ SDN
Sbjct: 263 PFSVGMLKSLVTFKCESNGLTELPDSISYLEQLEELVLS-------HNKLIRLPSTIGMLRSLRFLFADDNQLRQLPDELCSCQQLSVLSVANNQLSALPQNIGNLSKMKVLNVVNNYINALPVSMLNLVNLTSMWLSDN 395
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Fly
Match: scrib (gene:FBgn0263289 transcript:FBtr0308626) HSP 1 Score: 92.0485 bits (227), Expect = 9.728e-20 Identity = 78/280 (27.86%), Postives = 129/280 (46.07%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQF-GRLKLLDWSW----------------HYTSTTLDGNPLQ--HPPLDICKKGADEIEKYFKKMYGSSVVEVPAAKGGTS--NTLNFDVDAMRYL 895
++KL L ++ +PP++ N +L LD+S + ++P I L +L++ +N + +P L NL + L++ SLTTLP + +L +L SL + N + PE I ++ ++ D DN +P + L L L L NQL+ LP EL L ++ L + N+L +LP + G + L D T LD N LQ + L C+ + I + + + E+PA+ G + N LN D +A+ YL
Sbjct: 62 LRKLGLSDNEIGRLPPDIQNFENLVELDVSRN-------DIPDIPDDIKHLQSLQVADFSSNPIPKLPSGFSQLKNLTVLGLNDMSLTTLPADFGSLTQLESLELRENLLKHLPETISQLTKLKRLDLGDNEIEDLPPYLGYLPGLHELWLDHNQLQRLPPELGLLTKLTYLDVSENRLEELPNEISGLVSLTDLDLAQNLLEALPDGIAKLSRLTILKLDQNRLQRLNDTLGNCENMQELI------LTENFLSELPASIGQMTKLNNLNVDRNALEYL 328 HSP 2 Score: 87.8113 bits (216), Expect = 1.890e-18 Identity = 55/188 (29.26%), Postives = 96/188 (51.06%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGR 682
++ L+L+ L +P + L L+ LD+ +++++P +G L L L LD N L+ +P E+GLLT L + +S N L LPNEI L L L +A N E P+ I ++ + N + + ++ N ++++ L+L EN L LP + ++ ++ L + N L LP + G+
Sbjct: 154 LESLELRENLLKHLPETISQLTKLKRLDLGDN-------EIEDLPPYLGYLPGLHELWLDHNQLQRLPPELGLLTKLTYLDVSENRLEELPNEISGLVSLTDLDLAQNLLEALPDGIAKLSRLTILKLDQNRLQRLNDTLGNCENMQELILTENFLSELPASIGQMTKLNNLNVDRNALEYLPLEIGQ 334 HSP 3 Score: 87.4261 bits (215), Expect = 3.153e-18 Identity = 59/206 (28.64%), Postives = 97/206 (47.09%), Query Frame = 2
Query: 110 FYGMKKLKLQGKDLSSVPPELFNLLDLEVLDMS----PEREAGLY------------YKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFG 679
F + +L + D+ +P ++ +L L+V D S P+ +G L +P G L L+ L L N L+H+P+ I LT L+R+ L +N + LP + L L L + +N+ + P + + + + D S+N +P I L SL L L +N LE LPD + +L ++ L L N+L +L G
Sbjct: 82 FENLVELDVSRNDIPDIPDDIKHLQSLQVADFSSNPIPKLPSGFSQLKNLTVLGLNDMSLTTLPADFGSLTQLESLELRENLLKHLPETISQLTKLKRLDLGDNEIEDLPPYLGYLPGLHELWLDHNQLQRLPPELGLLTKLTYLDVSENRLEELPNEISGLVSLTDLDLAQNLLEALPDGIAKLSRLTILKLDQNRLQRLNDTLG 287 HSP 4 Score: 78.5666 bits (192), Expect = 2.439e-15 Identity = 48/175 (27.43%), Postives = 91/175 (52.00%), Query Frame = 2
Query: 239 LQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDI 763
++++P + +L L+ L L N++ +P +I NL + +S N + +P++IK+L+ L+ ++N P ++ ++ +D ++P +L LE+L L EN L+ LP+ + +L +++ L LG+N++ LP G L L W LD N LQ P ++
Sbjct: 49 IRDLPKNFFRLHRLRKLGLSDNEIGRLPPDIQNFENLVELDVSRNDIPDIPDDIKHLQSLQVADFSSNPIPKLPSGFSQLKNLTVLGLNDMSLTTLPADFGSLTQLESLELRENLLKHLPETISQLTKLKRLDLGDNEIEDLPPYLGYLPGLHELW------LDHNQLQRLPPEL 217 HSP 5 Score: 52.7582 bits (125), Expect = 4.370e-7 Identity = 28/74 (37.84%), Postives = 41/74 (55.41%), Query Frame = 2
Query: 239 LQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFP 460
L E+P SIG++ L L +D N L ++P EIG NL ++L +N L LP E+ N L L ++ N+ P
Sbjct: 302 LSELPASIGQMTKLNNLNVDRNALEYLPLEIGQCANLGVLSLRDNKLKKLPPELGNCTVLHVLDVSGNQLLYLP 375
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Fly
Match: scrib (gene:FBgn0263289 transcript:FBtr0308623) HSP 1 Score: 91.6633 bits (226), Expect = 9.761e-20 Identity = 78/280 (27.86%), Postives = 129/280 (46.07%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQF-GRLKLLDWSW----------------HYTSTTLDGNPLQ--HPPLDICKKGADEIEKYFKKMYGSSVVEVPAAKGGTS--NTLNFDVDAMRYL 895
++KL L ++ +PP++ N +L LD+S + ++P I L +L++ +N + +P L NL + L++ SLTTLP + +L +L SL + N + PE I ++ ++ D DN +P + L L L L NQL+ LP EL L ++ L + N+L +LP + G + L D T LD N LQ + L C+ + I + + + E+PA+ G + N LN D +A+ YL
Sbjct: 62 LRKLGLSDNEIGRLPPDIQNFENLVELDVSRN-------DIPDIPDDIKHLQSLQVADFSSNPIPKLPSGFSQLKNLTVLGLNDMSLTTLPADFGSLTQLESLELRENLLKHLPETISQLTKLKRLDLGDNEIEDLPPYLGYLPGLHELWLDHNQLQRLPPELGLLTKLTYLDVSENRLEELPNEISGLVSLTDLDLAQNLLEALPDGIAKLSRLTILKLDQNRLQRLNDTLGNCENMQELI------LTENFLSELPASIGQMTKLNNLNVDRNALEYL 328 HSP 2 Score: 87.8113 bits (216), Expect = 1.830e-18 Identity = 55/188 (29.26%), Postives = 96/188 (51.06%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGR 682
++ L+L+ L +P + L L+ LD+ +++++P +G L L L LD N L+ +P E+GLLT L + +S N L LPNEI L L L +A N E P+ I ++ + N + + ++ N ++++ L+L EN L LP + ++ ++ L + N L LP + G+
Sbjct: 154 LESLELRENLLKHLPETISQLTKLKRLDLGDN-------EIEDLPPYLGYLPGLHELWLDHNQLQRLPPELGLLTKLTYLDVSENRLEELPNEISGLVSLTDLDLAQNLLEALPDGIAKLSRLTILKLDQNRLQRLNDTLGNCENMQELILTENFLSELPASIGQMTKLNNLNVDRNALEYLPLEIGQ 334 HSP 3 Score: 87.4261 bits (215), Expect = 2.970e-18 Identity = 59/206 (28.64%), Postives = 97/206 (47.09%), Query Frame = 2
Query: 110 FYGMKKLKLQGKDLSSVPPELFNLLDLEVLDMS----PEREAGLY------------YKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFG 679
F + +L + D+ +P ++ +L L+V D S P+ +G L +P G L L+ L L N L+H+P+ I LT L+R+ L +N + LP + L L L + +N+ + P + + + + D S+N +P I L SL L L +N LE LPD + +L ++ L L N+L +L G
Sbjct: 82 FENLVELDVSRNDIPDIPDDIKHLQSLQVADFSSNPIPKLPSGFSQLKNLTVLGLNDMSLTTLPADFGSLTQLESLELRENLLKHLPETISQLTKLKRLDLGDNEIEDLPPYLGYLPGLHELWLDHNQLQRLPPELGLLTKLTYLDVSENRLEELPNEISGLVSLTDLDLAQNLLEALPDGIAKLSRLTILKLDQNRLQRLNDTLG 287 HSP 4 Score: 78.5666 bits (192), Expect = 2.432e-15 Identity = 48/175 (27.43%), Postives = 91/175 (52.00%), Query Frame = 2
Query: 239 LQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDI 763
++++P + +L L+ L L N++ +P +I NL + +S N + +P++IK+L+ L+ ++N P ++ ++ +D ++P +L LE+L L EN L+ LP+ + +L +++ L LG+N++ LP G L L W LD N LQ P ++
Sbjct: 49 IRDLPKNFFRLHRLRKLGLSDNEIGRLPPDIQNFENLVELDVSRNDIPDIPDDIKHLQSLQVADFSSNPIPKLPSGFSQLKNLTVLGLNDMSLTTLPADFGSLTQLESLELRENLLKHLPETISQLTKLKRLDLGDNEIEDLPPYLGYLPGLHELW------LDHNQLQRLPPEL 217 HSP 5 Score: 52.7582 bits (125), Expect = 4.372e-7 Identity = 28/74 (37.84%), Postives = 41/74 (55.41%), Query Frame = 2
Query: 239 LQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFP 460
L E+P SIG++ L L +D N L ++P EIG NL ++L +N L LP E+ N L L ++ N+ P
Sbjct: 302 LSELPASIGQMTKLNNLNVDRNALEYLPLEIGQCANLGVLSLRDNKLKKLPPELGNCTVLHVLDVSGNQLLYLP 375
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Fly
Match: scrib (gene:FBgn0263289 transcript:FBtr0308627) HSP 1 Score: 91.6633 bits (226), Expect = 9.860e-20 Identity = 78/280 (27.86%), Postives = 129/280 (46.07%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQF-GRLKLLDWSW----------------HYTSTTLDGNPLQ--HPPLDICKKGADEIEKYFKKMYGSSVVEVPAAKGGTS--NTLNFDVDAMRYL 895
++KL L ++ +PP++ N +L LD+S + ++P I L +L++ +N + +P L NL + L++ SLTTLP + +L +L SL + N + PE I ++ ++ D DN +P + L L L L NQL+ LP EL L ++ L + N+L +LP + G + L D T LD N LQ + L C+ + I + + + E+PA+ G + N LN D +A+ YL
Sbjct: 62 LRKLGLSDNEIGRLPPDIQNFENLVELDVSRN-------DIPDIPDDIKHLQSLQVADFSSNPIPKLPSGFSQLKNLTVLGLNDMSLTTLPADFGSLTQLESLELRENLLKHLPETISQLTKLKRLDLGDNEIEDLPPYLGYLPGLHELWLDHNQLQRLPPELGLLTKLTYLDVSENRLEELPNEISGLVSLTDLDLAQNLLEALPDGIAKLSRLTILKLDQNRLQRLNDTLGNCENMQELI------LTENFLSELPASIGQMTKLNNLNVDRNALEYL 328 HSP 2 Score: 87.8113 bits (216), Expect = 1.933e-18 Identity = 55/188 (29.26%), Postives = 96/188 (51.06%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGR 682
++ L+L+ L +P + L L+ LD+ +++++P +G L L L LD N L+ +P E+GLLT L + +S N L LPNEI L L L +A N E P+ I ++ + N + + ++ N ++++ L+L EN L LP + ++ ++ L + N L LP + G+
Sbjct: 154 LESLELRENLLKHLPETISQLTKLKRLDLGDN-------EIEDLPPYLGYLPGLHELWLDHNQLQRLPPELGLLTKLTYLDVSENRLEELPNEISGLVSLTDLDLAQNLLEALPDGIAKLSRLTILKLDQNRLQRLNDTLGNCENMQELILTENFLSELPASIGQMTKLNNLNVDRNALEYLPLEIGQ 334 HSP 3 Score: 87.4261 bits (215), Expect = 3.225e-18 Identity = 59/206 (28.64%), Postives = 97/206 (47.09%), Query Frame = 2
Query: 110 FYGMKKLKLQGKDLSSVPPELFNLLDLEVLDMS----PEREAGLY------------YKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFG 679
F + +L + D+ +P ++ +L L+V D S P+ +G L +P G L L+ L L N L+H+P+ I LT L+R+ L +N + LP + L L L + +N+ + P + + + + D S+N +P I L SL L L +N LE LPD + +L ++ L L N+L +L G
Sbjct: 82 FENLVELDVSRNDIPDIPDDIKHLQSLQVADFSSNPIPKLPSGFSQLKNLTVLGLNDMSLTTLPADFGSLTQLESLELRENLLKHLPETISQLTKLKRLDLGDNEIEDLPPYLGYLPGLHELWLDHNQLQRLPPELGLLTKLTYLDVSENRLEELPNEISGLVSLTDLDLAQNLLEALPDGIAKLSRLTILKLDQNRLQRLNDTLG 287 HSP 4 Score: 78.5666 bits (192), Expect = 2.472e-15 Identity = 48/175 (27.43%), Postives = 91/175 (52.00%), Query Frame = 2
Query: 239 LQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDI 763
++++P + +L L+ L L N++ +P +I NL + +S N + +P++IK+L+ L+ ++N P ++ ++ +D ++P +L LE+L L EN L+ LP+ + +L +++ L LG+N++ LP G L L W LD N LQ P ++
Sbjct: 49 IRDLPKNFFRLHRLRKLGLSDNEIGRLPPDIQNFENLVELDVSRNDIPDIPDDIKHLQSLQVADFSSNPIPKLPSGFSQLKNLTVLGLNDMSLTTLPADFGSLTQLESLELRENLLKHLPETISQLTKLKRLDLGDNEIEDLPPYLGYLPGLHELW------LDHNQLQRLPPEL 217 HSP 5 Score: 52.7582 bits (125), Expect = 4.432e-7 Identity = 28/74 (37.84%), Postives = 41/74 (55.41%), Query Frame = 2
Query: 239 LQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFP 460
L E+P SIG++ L L +D N L ++P EIG NL ++L +N L LP E+ N L L ++ N+ P
Sbjct: 302 LSELPASIGQMTKLNNLNVDRNALEYLPLEIGQCANLGVLSLRDNKLKKLPPELGNCTVLHVLDVSGNQLLYLP 375
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Zebrafish
Match: CABZ01080587.1 (leucine-rich repeat-containing protein 30-like [Source:NCBI gene;Acc:100534875]) HSP 1 Score: 108.227 bits (269), Expect = 1.654e-26 Identity = 71/231 (30.74%), Postives = 127/231 (54.98%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLD-WSWHYTSTTLD--GNPLQHPPLDICKKGADEIEKYFK 802
++KL L LS++P + NL +L +L++ L ++P IG+L+NL++L N L VP+E+G +NLE ++L+NN + LPN + +L+KL L++++N+ + P + + ++F ++N ++ I+ L+SL+ L+L +N L+ LP LC L + L + +N+L LP+ RL+ L + H L NPL P ++ + G + Y K
Sbjct: 82 LQKLNLSLNTLSTLPAAVGNLQNLVILNLWGN-------DLLDLPPEIGRLVNLRVLFAHKNRLTDVPEELGHCSNLEVLSLANNQINALPNSLCSLRKLTKLNLSHNRIQHIPACVYSMRGLQFLHLANNRLENLADKIQELQSLKILILEQNLLQVLPRTLCCLTALELLNVDHNELQSLPEDMHRLRRLQKLACHPLDKGLHVVHNPLLKPIREVLQDGLTGLYSYLK 305
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Zebrafish
Match: mfhas1 (malignant fibrous histiocytoma amplified sequence 1 [Source:ZFIN;Acc:ZDB-GENE-080917-20]) HSP 1 Score: 111.694 bits (278), Expect = 2.553e-26 Identity = 80/243 (32.92%), Postives = 122/243 (50.21%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLD-WSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFKKMYGSSVVEVPAAK 844
++ L + L P E+ L DLE LD S KL+ +P +I L ++KIL L + L +P+ L NLE + L NN LT LP L+KL+ L++++N FE FP++I ++ +E S N +P+ + L +L L L N + LPD + EL ++ L L N++ LP FG+L ++ W + NPL PP ++C KG I Y K++ S P K
Sbjct: 165 LRTLDVDHNKLQRFPSEILALSDLEELDCSGN-------KLEGLPGNIMMLQSIKILWLSSTHLLSLPETFCELQNLESLMLDNNFLTRLPQSFGKLQKLKMLNLSSNSFEDFPQVIIKLTRLEELYLSRNKLTFLPEEVGQLCNLANLWLDNNSITFLPDSIVELGKLEELVLQGNQIAILPDNFGKLAKVNIWK-------VKDNPLIQPPYEVCMKGIPYIAAYQKELAHSQPAIKPRLK 393 HSP 2 Score: 98.9821 bits (245), Expect = 4.680e-22 Identity = 68/209 (32.54%), Postives = 104/209 (49.76%), Query Frame = 2
Query: 68 NKSLRMMVDTEDPLFYGMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLL 694
N SL+ + + ++ L L+ + VP +F L L LD+S + L I L LK L N ++++P +IG L +LE + +S N L P L+KLR+L + +NK + FP I + +E D S N +P +I L+S++ L L L LP+ CEL + L L NN LT+LP+ FG+L+ L
Sbjct: 56 NNSLQELPEGLGSTLTKLRILILRRNKFAIVPSAVFQLSQLVELDIS-------HNCLNHFSEDIDLLKGLKKLCFSHNKIQYLPSQIGTLQSLEELDISFNELHDFPRSFSQLRKLRTLDVDHNKLQRFPSEILALSDLEELDCSGNKLEGLPGNIMMLQSIKILWLSSTHLLSLPETFCELQNLESLMLDNNFLTRLPQSFGKLQKL 257 HSP 3 Score: 80.1073 bits (196), Expect = 8.425e-16 Identity = 56/178 (31.46%), Postives = 84/178 (47.19%), Query Frame = 2
Query: 236 KLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDICK 769
K VP ++ +L L L + N L H ++I LL L+++ S+N + LP++I L+ L L I+ N+ FP ++ + D N + P I L LE L N+LEGLP + L ++ LWL + L LP+ F L+ L+ S LD N L P K
Sbjct: 82 KFAIVPSAVFQLSQLVELDISHNCLNHFSEDIDLLKGLKKLCFSHNKIQYLPSQIGTLQSLEELDISFNELHDFPRSFSQLRKLRTLDVDHNKLQRFPSEILALSDLEELDCSGNKLEGLPGNIMMLQSIKILWLSSTHLLSLPETFCELQNLE------SLMLDNNFLTRLPQSFGK 253 HSP 4 Score: 72.4034 bits (176), Expect = 2.902e-13 Identity = 66/224 (29.46%), Postives = 106/224 (47.32%), Query Frame = 2
Query: 53 MADKKN-KSLRMMVDT---EDPLFYGMKKLKLQGKDLSSVP-PELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLN-LKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSW 706
MA++ N K+ R+ D L +++L L K+ + PE ++ ++EVL++ LQE+P +G L L+IL+L N VP + L+ L + +S+N L +I LK L+ L ++NK + P I + S+E D S N P+S L+ L TL + N+L+ P E+ L + L NKL LP L+ + W
Sbjct: 1 MAEETNLKTARLWRDAALRSRKLRSNLRQLTLSTKNSQKITLPE--DIKEIEVLNLGNN-------SLQELPEGLGSTLTKLRILILRRNKFAIVPSAVFQLSQLVELDISHNCLNHFSEDIDLLKGLKKLCFSHNKIQYLPSQIGTLQSLEELDISFNELHDFPRSFSQLRKLRTLDVDHNKLQRFPSEILALSDLEELDCSGNKLEGLPGNIMMLQSIKILW 215
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Zebrafish
Match: mfhas1 (malignant fibrous histiocytoma amplified sequence 1 [Source:ZFIN;Acc:ZDB-GENE-080917-20]) HSP 1 Score: 111.309 bits (277), Expect = 2.942e-26 Identity = 80/243 (32.92%), Postives = 122/243 (50.21%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLD-WSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFKKMYGSSVVEVPAAK 844
++ L + L P E+ L DLE LD S KL+ +P +I L ++KIL L + L +P+ L NLE + L NN LT LP L+KL+ L++++N FE FP++I ++ +E S N +P+ + L +L L L N + LPD + EL ++ L L N++ LP FG+L ++ W + NPL PP ++C KG I Y K++ S P K
Sbjct: 165 LRTLDVDHNKLQRFPSEILALSDLEELDCSGN-------KLEGLPGNIMMLQSIKILWLSSTHLLSLPETFCELQNLESLMLDNNFLTRLPQSFGKLQKLKMLNLSSNSFEDFPQVIIKLTRLEELYLSRNKLTFLPEEVGQLCNLANLWLDNNSITFLPDSIVELGKLEELVLQGNQIAILPDNFGKLAKVNIWK-------VKDNPLIQPPYEVCMKGIPYIAAYQKELAHSQPAIKPRLK 393 HSP 2 Score: 98.9821 bits (245), Expect = 5.000e-22 Identity = 68/209 (32.54%), Postives = 104/209 (49.76%), Query Frame = 2
Query: 68 NKSLRMMVDTEDPLFYGMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLL 694
N SL+ + + ++ L L+ + VP +F L L LD+S + L I L LK L N ++++P +IG L +LE + +S N L P L+KLR+L + +NK + FP I + +E D S N +P +I L+S++ L L L LP+ CEL + L L NN LT+LP+ FG+L+ L
Sbjct: 56 NNSLQELPEGLGSTLTKLRILILRRNKFAIVPSAVFQLSQLVELDIS-------HNCLNHFSEDIDLLKGLKKLCFSHNKIQYLPSQIGTLQSLEELDISFNELHDFPRSFSQLRKLRTLDVDHNKLQRFPSEILALSDLEELDCSGNKLEGLPGNIMMLQSIKILWLSSTHLLSLPETFCELQNLESLMLDNNFLTRLPQSFGKLQKL 257 HSP 3 Score: 79.7221 bits (195), Expect = 9.836e-16 Identity = 56/178 (31.46%), Postives = 84/178 (47.19%), Query Frame = 2
Query: 236 KLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDICK 769
K VP ++ +L L L + N L H ++I LL L+++ S+N + LP++I L+ L L I+ N+ FP ++ + D N + P I L LE L N+LEGLP + L ++ LWL + L LP+ F L+ L+ S LD N L P K
Sbjct: 82 KFAIVPSAVFQLSQLVELDISHNCLNHFSEDIDLLKGLKKLCFSHNKIQYLPSQIGTLQSLEELDISFNELHDFPRSFSQLRKLRTLDVDHNKLQRFPSEILALSDLEELDCSGNKLEGLPGNIMMLQSIKILWLSSTHLLSLPETFCELQNLE------SLMLDNNFLTRLPQSFGK 253 HSP 4 Score: 72.0182 bits (175), Expect = 3.036e-13 Identity = 66/224 (29.46%), Postives = 106/224 (47.32%), Query Frame = 2
Query: 53 MADKKN-KSLRMMVDT---EDPLFYGMKKLKLQGKDLSSVP-PELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLN-LKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSW 706
MA++ N K+ R+ D L +++L L K+ + PE ++ ++EVL++ LQE+P +G L L+IL+L N VP + L+ L + +S+N L +I LK L+ L ++NK + P I + S+E D S N P+S L+ L TL + N+L+ P E+ L + L NKL LP L+ + W
Sbjct: 1 MAEETNLKTARLWRDAALRSRKLRSNLRQLTLSTKNSQKITLPE--DIKEIEVLNLGNN-------SLQELPEGLGSTLTKLRILILRRNKFAIVPSAVFQLSQLVELDISHNCLNHFSEDIDLLKGLKKLCFSHNKIQYLPSQIGTLQSLEELDISFNELHDFPRSFSQLRKLRTLDVDHNKLQRFPSEILALSDLEELDCSGNKLEGLPGNIMMLQSIKILW 215
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Zebrafish
Match: mfhas1 (malignant fibrous histiocytoma amplified sequence 1 [Source:ZFIN;Acc:ZDB-GENE-080917-20]) HSP 1 Score: 111.309 bits (277), Expect = 2.942e-26 Identity = 80/243 (32.92%), Postives = 122/243 (50.21%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLD-WSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFKKMYGSSVVEVPAAK 844
++ L + L P E+ L DLE LD S KL+ +P +I L ++KIL L + L +P+ L NLE + L NN LT LP L+KL+ L++++N FE FP++I ++ +E S N +P+ + L +L L L N + LPD + EL ++ L L N++ LP FG+L ++ W + NPL PP ++C KG I Y K++ S P K
Sbjct: 165 LRTLDVDHNKLQRFPSEILALSDLEELDCSGN-------KLEGLPGNIMMLQSIKILWLSSTHLLSLPETFCELQNLESLMLDNNFLTRLPQSFGKLQKLKMLNLSSNSFEDFPQVIIKLTRLEELYLSRNKLTFLPEEVGQLCNLANLWLDNNSITFLPDSIVELGKLEELVLQGNQIAILPDNFGKLAKVNIWK-------VKDNPLIQPPYEVCMKGIPYIAAYQKELAHSQPAIKPRLK 393 HSP 2 Score: 98.9821 bits (245), Expect = 5.000e-22 Identity = 68/209 (32.54%), Postives = 104/209 (49.76%), Query Frame = 2
Query: 68 NKSLRMMVDTEDPLFYGMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLL 694
N SL+ + + ++ L L+ + VP +F L L LD+S + L I L LK L N ++++P +IG L +LE + +S N L P L+KLR+L + +NK + FP I + +E D S N +P +I L+S++ L L L LP+ CEL + L L NN LT+LP+ FG+L+ L
Sbjct: 56 NNSLQELPEGLGSTLTKLRILILRRNKFAIVPSAVFQLSQLVELDIS-------HNCLNHFSEDIDLLKGLKKLCFSHNKIQYLPSQIGTLQSLEELDISFNELHDFPRSFSQLRKLRTLDVDHNKLQRFPSEILALSDLEELDCSGNKLEGLPGNIMMLQSIKILWLSSTHLLSLPETFCELQNLESLMLDNNFLTRLPQSFGKLQKL 257 HSP 3 Score: 79.7221 bits (195), Expect = 9.836e-16 Identity = 56/178 (31.46%), Postives = 84/178 (47.19%), Query Frame = 2
Query: 236 KLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDICK 769
K VP ++ +L L L + N L H ++I LL L+++ S+N + LP++I L+ L L I+ N+ FP ++ + D N + P I L LE L N+LEGLP + L ++ LWL + L LP+ F L+ L+ S LD N L P K
Sbjct: 82 KFAIVPSAVFQLSQLVELDISHNCLNHFSEDIDLLKGLKKLCFSHNKIQYLPSQIGTLQSLEELDISFNELHDFPRSFSQLRKLRTLDVDHNKLQRFPSEILALSDLEELDCSGNKLEGLPGNIMMLQSIKILWLSSTHLLSLPETFCELQNLE------SLMLDNNFLTRLPQSFGK 253 HSP 4 Score: 72.0182 bits (175), Expect = 3.036e-13 Identity = 66/224 (29.46%), Postives = 106/224 (47.32%), Query Frame = 2
Query: 53 MADKKN-KSLRMMVDT---EDPLFYGMKKLKLQGKDLSSVP-PELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLN-LKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSW 706
MA++ N K+ R+ D L +++L L K+ + PE ++ ++EVL++ LQE+P +G L L+IL+L N VP + L+ L + +S+N L +I LK L+ L ++NK + P I + S+E D S N P+S L+ L TL + N+L+ P E+ L + L NKL LP L+ + W
Sbjct: 1 MAEETNLKTARLWRDAALRSRKLRSNLRQLTLSTKNSQKITLPE--DIKEIEVLNLGNN-------SLQELPEGLGSTLTKLRILILRRNKFAIVPSAVFQLSQLVELDISHNCLNHFSEDIDLLKGLKKLCFSHNKIQYLPSQIGTLQSLEELDISFNELHDFPRSFSQLRKLRTLDVDHNKLQRFPSEILALSDLEELDCSGNKLEGLPGNIMMLQSIKILW 215
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Zebrafish
Match: BX511222.1 (malignant fibrous histiocytoma amplified sequence 1 [Source:NCBI gene;Acc:797005]) HSP 1 Score: 110.923 bits (276), Expect = 4.603e-26 Identity = 79/243 (32.51%), Postives = 122/243 (50.21%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLD-WSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFKKMYGSSVVEVPAAK 844
++ L + L P E+ L DLE LD S KL+ +P +I L ++KIL L + L +P+ L NLE + L NN LT LP ++KL+ L++++N FE FP++I ++ +E S N +P+ + L +L L L N + LPD + EL ++ L L N++ LP FG+L ++ W + NPL PP ++C KG I Y K++ S P K
Sbjct: 165 LRTLDVDHNKLQRFPSEILALSDLEELDCSGN-------KLEGLPGNIMMLQSIKILWLSSTHLLSLPETFCELQNLESLMLDNNFLTRLPQSFGKMQKLKMLNLSSNSFEDFPQVIIKLTKLEELYLSRNKLTFLPEEVGQLCNLANLWLDNNSITFLPDSIVELGKLEELVLQGNQIAILPDNFGKLAKVNIWK-------VKDNPLIQPPYEVCMKGIPYIAAYQKELAHSQPAIKPRLK 393 HSP 2 Score: 99.3673 bits (246), Expect = 3.150e-22 Identity = 67/209 (32.06%), Postives = 105/209 (50.24%), Query Frame = 2
Query: 68 NKSLRMMVDTEDPLFYGMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLL 694
N SL+ + + ++ L L+ ++VP +F L L LD+S + L I L LK L N ++++P +IG L +LE + +S N L P L+KLR+L + +NK + FP I + +E D S N +P +I L+S++ L L L LP+ CEL + L L NN LT+LP+ FG+++ L
Sbjct: 56 NNSLQELPEGLGSTLTKLRILILRRNKFATVPSAVFQLSQLVELDIS-------HNCLNHFSEDIDLLKGLKKLCFSHNRIQYLPSQIGTLQSLEELDISFNELHDFPRSFSQLRKLRTLDVDHNKLQRFPSEILALSDLEELDCSGNKLEGLPGNIMMLQSIKILWLSSTHLLSLPETFCELQNLESLMLDNNFLTRLPQSFGKMQKL 257 HSP 3 Score: 80.4925 bits (197), Expect = 5.355e-16 Identity = 56/178 (31.46%), Postives = 84/178 (47.19%), Query Frame = 2
Query: 236 KLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDICK 769
K VP ++ +L L L + N L H ++I LL L+++ S+N + LP++I L+ L L I+ N+ FP ++ + D N + P I L LE L N+LEGLP + L ++ LWL + L LP+ F L+ L+ S LD N L P K
Sbjct: 82 KFATVPSAVFQLSQLVELDISHNCLNHFSEDIDLLKGLKKLCFSHNRIQYLPSQIGTLQSLEELDISFNELHDFPRSFSQLRKLRTLDVDHNKLQRFPSEILALSDLEELDCSGNKLEGLPGNIMMLQSIKILWLSSTHLLSLPETFCELQNLE------SLMLDNNFLTRLPQSFGK 253 HSP 4 Score: 72.0182 bits (175), Expect = 3.601e-13 Identity = 65/224 (29.02%), Postives = 106/224 (47.32%), Query Frame = 2
Query: 53 MADKKN-KSLRMMVDT---EDPLFYGMKKLKLQGKDLSSVP-PELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLN-LKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSW 706
MA++ N K+ R+ D L +++L L K+ + PE ++ ++EVL++ LQE+P +G L L+IL+L N VP + L+ L + +S+N L +I LK L+ L ++N+ + P I + S+E D S N P+S L+ L TL + N+L+ P E+ L + L NKL LP L+ + W
Sbjct: 1 MAEETNLKTARLWRDAALRSRKLRSNLRQLTLSTKNSQKITLPE--DIKEIEVLNLGNN-------SLQELPEGLGSTLTKLRILILRRNKFATVPSAVFQLSQLVELDISHNCLNHFSEDIDLLKGLKKLCFSHNRIQYLPSQIGTLQSLEELDISFNELHDFPRSFSQLRKLRTLDVDHNKLQRFPSEILALSDLEELDCSGNKLEGLPGNIMMLQSIKILW 215
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Xenopus
Match: jag1 (jagged 1 [Source:Xenbase;Acc:XB-GENE-485662]) HSP 1 Score: 113.62 bits (283), Expect = 7.204e-27 Identity = 81/244 (33.20%), Postives = 124/244 (50.82%), Query Frame = 2
Query: 116 GMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLD-WSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFKKMYGSSVVEVPAAK 844
++ L L +L S P +LF++ LE LD S + G +P I + +LKIL L + L +P I L NLE + L NN+L TLP L+KL+ L++++N F+ FP + +++ +E S N +P+ I + L TL L N++ LPD + EL + L L N++ LP FG+L ++ W + NPL PP ++C KG I Y K++ S PA K
Sbjct: 173 SLRTLDLDHNELCSFPQQLFHVPALEELDFSGNKMLG------SLPEGIRSMQSLKILWLSSTSLCLLPDSICELVNLESLMLDNNNLHTLPEGFGALQKLKMLNVSSNAFQDFPVPLLQLVDLEELYMSRNRLVVLPEVISCMTKLVTLWLDNNRIRYLPDSIVELSFLEELVLQGNQIAILPDDFGKLSKVNIWK-------IKDNPLIQPPYEVCMKGISYIAAYQKELAHSQ----PAVK 399 HSP 2 Score: 80.4925 bits (197), Expect = 8.077e-16 Identity = 66/225 (29.33%), Postives = 106/225 (47.11%), Query Frame = 2
Query: 176 NLLDLEVLDMSPEREAGLYYKLQEVP-----LSIGKLLNLKILML----------------------------------------------DTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDN-MFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLL 694
+L D+EVL++ L+EVP LS G NL +L+L N L +P+++G+L +LE + +S N +T LP+ ++ L LR+L + +N+ +FP+ + + ++E D S N M S+P+ IR+++SL+ L L L LPD +CEL+ + L L NN L LP+ FG L+ L
Sbjct: 53 DLGDVEVLNLGNN-------SLEEVPDGLQSLSAG---NLHVLILRRNKFLNVPTAVYHLGRLTELDISYNRLSCLTEAVGLLGKLKKLCLSHNQLHTLPRQLGMLVDLEELDVSFNQITHLPDTMQGLPSLRTLDLDHNELCSFPQQLFHVPALEELDFSGNKMLGSLPEGIRSMQSLKILWLSSTSLCLLPDSICELVNLESLMLDNNNLHTLPEGFGALQKL 267 HSP 3 Score: 55.8398 bits (133), Expect = 7.067e-8 Identity = 40/147 (27.21%), Postives = 70/147 (47.62%), Query Frame = 2
Query: 263 GKLLNLKILMLDTNDLRHVPKEIGLLT--NLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLD 697
L ++++L L N L VP + L+ NL + L N +P + +L +L L I+ N+ E + + ++ S N ++P+ + L LE L + NQ+ LPD + L +R L L +N+L P+Q + L+
Sbjct: 52 ADLGDVEVLNLGNNSLEEVPDGLQSLSAGNLHVLILRRNKFLNVPTAVYHLGRLTELDISYNRLSCLTEAVGLLGKLKKLCLSHNQLHTLPRQLGMLVDLEELDVSFNQITHLPDTMQGLPSLRTLDLDHNELCSFPQQLFHVPALE 198
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Xenopus
Match: heatr3 (HEAT repeat containing 3 [Source:Xenbase;Acc:XB-GENE-5805167]) HSP 1 Score: 102.064 bits (253), Expect = 4.034e-23 Identity = 80/238 (33.61%), Postives = 115/238 (48.32%), Query Frame = 2
Query: 128 LKLQGKDLSSVPPELF--NLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFKKMYGSSVVEVP 835
L L G+ L P +L D D+S R L E+P I ++L+ L N +RHVP+ L L + +S N LT+LP + +L L+ L ++NNK ++ PE I + ++ D S N +++P I L+SL L + N L LP EL EL +R L NK+T +P + L+ H + LD NPLQ PP IC KG I KY S ++P
Sbjct: 63 LNLSGRKLREFPRSAVQHDLSDTTQADLSRNR-------LCEIPPEICNYVSLETLSFYQNCIRHVPEATLNLQALSFLNISRNQLTSLPGHLCSLP-LKVLIVSNNKLDSLPEEIGALRNLTELDVSCNEIQTIPTQIGKLESLRDLNIRRNHLVQLPHELAELPLVR-LDFSCNKVTCIPVCYRNLR------HLQTIMLDNNPLQSPPAQICIKGKIHIFKYLNIEACKSAPDIP 285
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Xenopus
Match: heatr3 (HEAT repeat containing 3 [Source:Xenbase;Acc:XB-GENE-5805167]) HSP 1 Score: 102.449 bits (254), Expect = 4.353e-23 Identity = 80/238 (33.61%), Postives = 115/238 (48.32%), Query Frame = 2
Query: 128 LKLQGKDLSSVPPELF--NLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFKKMYGSSVVEVP 835
L L G+ L P +L D D+S R L E+P I ++L+ L N +RHVP+ L L + +S N LT+LP + +L L+ L ++NNK ++ PE I + ++ D S N +++P I L+SL L + N L LP EL EL +R L NK+T +P + L+ H + LD NPLQ PP IC KG I KY S ++P
Sbjct: 63 LNLSGRKLREFPRSAVQHDLSDTTQADLSRNR-------LCEIPPEICNYVSLETLSFYQNCIRHVPEATLNLQALSFLNISRNQLTSLPGHLCSLP-LKVLIVSNNKLDSLPEEIGALRNLTELDVSCNEIQTIPTQIGKLESLRDLNIRRNHLVQLPHELAELPLVR-LDFSCNKVTCIPVCYRNLR------HLQTIMLDNNPLQSPPAQICIKGKIHIFKYLNIEACKSAPDIP 285
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Xenopus
Match: heatr3 (HEAT repeat containing 3 [Source:Xenbase;Acc:XB-GENE-5805167]) HSP 1 Score: 102.064 bits (253), Expect = 5.545e-23 Identity = 80/238 (33.61%), Postives = 115/238 (48.32%), Query Frame = 2
Query: 128 LKLQGKDLSSVPPELF--NLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFKKMYGSSVVEVP 835
L L G+ L P +L D D+S R L E+P I ++L+ L N +RHVP+ L L + +S N LT+LP + +L L+ L ++NNK ++ PE I + ++ D S N +++P I L+SL L + N L LP EL EL +R L NK+T +P + L+ H + LD NPLQ PP IC KG I KY S ++P
Sbjct: 82 LNLSGRKLREFPRSAVQHDLSDTTQADLSRNR-------LCEIPPEICNYVSLETLSFYQNCIRHVPEATLNLQALSFLNISRNQLTSLPGHLCSLP-LKVLIVSNNKLDSLPEEIGALRNLTELDVSCNEIQTIPTQIGKLESLRDLNIRRNHLVQLPHELAELPLVR-LDFSCNKVTCIPVCYRNLR------HLQTIMLDNNPLQSPPAQICIKGKIHIFKYLNIEACKSAPDIP 304
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Xenopus
Match: heatr3 (HEAT repeat containing 3 [Source:Xenbase;Acc:XB-GENE-5805167]) HSP 1 Score: 101.293 bits (251), Expect = 7.664e-23 Identity = 80/238 (33.61%), Postives = 115/238 (48.32%), Query Frame = 2
Query: 128 LKLQGKDLSSVPPELF--NLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFKKMYGSSVVEVP 835
L L G+ L P +L D D+S R L E+P I ++L+ L N +RHVP+ L L + +S N LT+LP + +L L+ L ++NNK ++ PE I + ++ D S N +++P I L+SL L + N L LP EL EL +R L NK+T +P + L+ H + LD NPLQ PP IC KG I KY S ++P
Sbjct: 45 LNLSGRKLREFPRSAVQHDLSDTTQADLSRNR-------LCEIPPEICNYVSLETLSFYQNCIRHVPEATLNLQALSFLNISRNQLTSLPGHLCSLP-LKVLIVSNNKLDSLPEEIGALRNLTELDVSCNEIQTIPTQIGKLESLRDLNIRRNHLVQLPHELAELPLVR-LDFSCNKVTCIPVCYRNLR------HLQTIMLDNNPLQSPPAQICIKGKIHIFKYLNIEACKSAPDIP 267
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Mouse
Match: Mfhas1 (malignant fibrous histiocytoma amplified sequence 1 [Source:MGI Symbol;Acc:MGI:1098644]) HSP 1 Score: 105.145 bits (261), Expect = 3.676e-24 Identity = 70/204 (34.31%), Postives = 102/204 (50.00%), Query Frame = 2
Query: 236 KLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLD-WSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFKKMYGSSVVEVPAAK 844
+L+ +P I L LKIL L +L +P+ L +LE + L NN L LP+E L++L+ L++++N FE FP + + +E S N SVP I L L TL L N++ LPD + EL + L L N++ LP FG+L + W + NPL PP ++C KG I Y K++ S P K
Sbjct: 17 RLRGLPEDISALRALKILWLSGAELGTLPRGFCELASLESLMLDNNGLQALPDEFSRLQRLKMLNLSSNLFEEFPAALLPLAGLEELYLSRNQLTSVPSLIAGLGRLLTLWLDNNRIRYLPDSIVELTGLEELVLQGNQIAVLPDNFGQLSRVGLWK-------IKDNPLIQPPYEVCMKGIPYIAAYQKELAHSQPAVQPRLK 213
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Mouse
Match: Mfhas1 (malignant fibrous histiocytoma amplified sequence 1 [Source:MGI Symbol;Acc:MGI:1098644]) HSP 1 Score: 105.145 bits (261), Expect = 4.534e-24 Identity = 70/204 (34.31%), Postives = 102/204 (50.00%), Query Frame = 2
Query: 236 KLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLD-WSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFKKMYGSSVVEVPAAK 844
+L+ +P I L LKIL L +L +P+ L +LE + L NN L LP+E L++L+ L++++N FE FP + + +E S N SVP I L L TL L N++ LPD + EL + L L N++ LP FG+L + W + NPL PP ++C KG I Y K++ S P K
Sbjct: 211 RLRGLPEDISALRALKILWLSGAELGTLPRGFCELASLESLMLDNNGLQALPDEFSRLQRLKMLNLSSNLFEEFPAALLPLAGLEELYLSRNQLTSVPSLIAGLGRLLTLWLDNNRIRYLPDSIVELTGLEELVLQGNQIAVLPDNFGQLSRVGLWK-------IKDNPLIQPPYEVCMKGIPYIAAYQKELAHSQPAVQPRLK 407 HSP 2 Score: 85.5001 bits (210), Expect = 1.384e-17 Identity = 62/193 (32.12%), Postives = 99/193 (51.30%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNL-LDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLL 694
++ L L+ + +PP + L L LD+S R L ++ + L L+ L L N L +P ++G L +LE + +S N L LP+ L LR+L + +N+ FP+ + ++ ++E D S N R +P+ I L++L+ L L +L LP CEL + L L NN L LP +F RL+ L
Sbjct: 85 LRVLVLRRNRFARLPPAVAELGHHLTELDVSHNRLTILGAEV------VSALRELRKLNLSHNQLPALPAQLGALAHLEELDVSFNRLAHLPDSFSCLNHLRTLDVDHNQLTAFPQQLLQLAALEELDVSSNRLRGLPEDISALRALKILWLSGAELGTLPRGFCELASLESLMLDNNGLQALPDEFSRLQRL 271
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Mouse
Match: Gm20605 (predicted gene 20605 [Source:MGI Symbol;Acc:MGI:5306917]) HSP 1 Score: 102.064 bits (253), Expect = 3.628e-23 Identity = 78/214 (36.45%), Postives = 110/214 (51.40%), Query Frame = 2
Query: 173 FNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFKKMYG 814
++L D+ D+S R EVP + +L++L+ L L N L+ + +G LT L + LS N L++LP I L LR L I+NNK P I + S+ D S N +S+P + +L+SL L + NQL LPDEL +L +R L N+++++P F RL+ H LD NPLQ PP IC KG I KY G
Sbjct: 65 YDLSDITQADLSRNR-------FPEVPEAACQLVSLEGLSLYHNCLKCLNPALGNLTALTYLNLSRNQLSSLPPYICQLP-LRVLIISNNKLGALPPDISTLGSLRQLDVSSNELQSLPVELCSLRSLRDLNVRRNQLSTLPDELGDLPLVR-LDFSCNRISRIPVSFCRLR------HLQVVLLDSNPLQSPPAQICLKGKLHIFKYLTMEAG 263
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Mouse
Match: Lrch4 (leucine-rich repeats and calponin homology (CH) domain containing 4 [Source:MGI Symbol;Acc:MGI:1917193]) HSP 1 Score: 102.064 bits (253), Expect = 3.628e-23 Identity = 78/214 (36.45%), Postives = 110/214 (51.40%), Query Frame = 2
Query: 173 FNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFKKMYG 814
++L D+ D+S R EVP + +L++L+ L L N L+ + +G LT L + LS N L++LP I L LR L I+NNK P I + S+ D S N +S+P + +L+SL L + NQL LPDEL +L +R L N+++++P F RL+ H LD NPLQ PP IC KG I KY G
Sbjct: 65 YDLSDITQADLSRNR-------FPEVPEAACQLVSLEGLSLYHNCLKCLNPALGNLTALTYLNLSRNQLSSLPPYICQLP-LRVLIISNNKLGALPPDISTLGSLRQLDVSSNELQSLPVELCSLRSLRDLNVRRNQLSTLPDELGDLPLVR-LDFSCNRISRIPVSFCRLR------HLQVVLLDSNPLQSPPAQICLKGKLHIFKYLTMEAG 263
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Mouse
Match: Lrch4 (leucine-rich repeats and calponin homology (CH) domain containing 4 [Source:MGI Symbol;Acc:MGI:1917193]) HSP 1 Score: 101.679 bits (252), Expect = 5.532e-23 Identity = 73/193 (37.82%), Postives = 102/193 (52.85%), Query Frame = 2
Query: 236 KLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFKKMYG 814
+ EVP + +L++L+ L L N L+ + +G LT L + LS N L++LP I L LR L I+NNK P I + S+ D S N +S+P + +L+SL L + NQL LPDEL +L +R L N+++++P F RL+ H LD NPLQ PP IC KG I KY G
Sbjct: 25 RFPEVPEAACQLVSLEGLSLYHNCLKCLNPALGNLTALTYLNLSRNQLSSLPPYICQLP-LRVLIISNNKLGALPPDISTLGSLRQLDVSSNELQSLPVELCSLRSLRDLNVRRNQLSTLPDELGDLPLVR-LDFSCNRISRIPVSFCRLR------HLQVVLLDSNPLQSPPAQICLKGKLHIFKYLTMEAG 209
BLAST of Leucine-rich repeat-containing protein 57 vs. UniProt/SwissProt
Match: sp|Q9LRV8|PIRL2_ARATH (Plant intracellular Ras-group-related LRR protein 2 OS=Arabidopsis thaliana OX=3702 GN=PIRL2 PE=2 SV=1) HSP 1 Score: 126.331 bits (316), Expect = 4.246e-31 Identity = 88/257 (34.24%), Postives = 133/257 (51.75%), Query Frame = 2
Query: 116 GMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIK-NLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYEN--QLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFKKMYGSSVVE------VPAAKGGTSN 859
G+ L L G DL+ +P + L LE LD+S L+ +P SIG LLNL+IL ++ N+L +P+ I +L + S N+LT+LP I L+ L L I NK FP I E+ ++++ DA N +P SI L LE L L N L G+PD + +L +R L L NN++ +P F RL+ L+ LD NPL+ P ++ +GA+ + ++ +K +G + E V A + G N
Sbjct: 184 GLVYLNLSGNDLTFIPDAISKLKKLEELDVSSN-------SLESLPDSIGMLLNLRILNVNANNLTALPESIAHCRSLVELDASYNNLTSLPTNIGYGLQNLERLSIQLNKLRYFPGSISEMYNLKYLDAHMNEIHGIPNSIGRLTKLEVLNLSSNFNNLMGVPDTITDLTNLRELDLSNNQIQAIPDSFYRLRKLE------KLNLDQNPLEIPSQEVATQGAEVVREFMRKRWGDIMAEQQQRIGVEAERHGDEN 427 HSP 2 Score: 51.6026 bits (122), Expect = 7.559e-6 Identity = 44/151 (29.14%), Postives = 65/151 (43.05%), Query Frame = 2
Query: 227 LYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFG 679
+Y E L G+ +N K+L V KE +ERI LS+ L +P + L L+++ N P+ I ++ +E D S N S+P SI L +L L + N L LP+ + + L N LT LP G
Sbjct: 130 VYSTEVESMLRSGEEVNEKVLA--------VLKEAESGGTVERIDLSSQELKLIPEAFWKVVGLVYLNLSGNDLTFIPDAISKLKKLEELDVSSNSLESLPDSIGMLLNLRILNVNANNLTALPESIAHCRSLVELDASYNNLTSLPTNIG 272
BLAST of Leucine-rich repeat-containing protein 57 vs. UniProt/SwissProt
Match: sp|A4IIK1|MFHA1_XENTR (Malignant fibrous histiocytoma-amplified sequence 1 homolog OS=Xenopus tropicalis OX=8364 GN=mfhas1 PE=2 SV=1) HSP 1 Score: 114.005 bits (284), Expect = 3.606e-26 Identity = 81/244 (33.20%), Postives = 124/244 (50.82%), Query Frame = 2
Query: 116 GMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLD-WSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFKKMYGSSVVEVPAAK 844
++ L L +L S P +LF++ LE LD S + G +P I + +LKIL L + L +P I L NLE + L NN+L TLP L+KL+ L++++N F+ FP + +++ +E S N +P+ I + L TL L N++ LPD + EL + L L N++ LP FG+L ++ W + NPL PP ++C KG I Y K++ S PA K
Sbjct: 171 SLRTLDLDHNELCSFPQQLFHVPALEELDFSGNKMLG------SLPEGIRSMQSLKILWLSSTSLCLLPDSICELVNLESLMLDNNNLHTLPEGFGALQKLKMLNVSSNAFQDFPVPLLQLVDLEELYMSRNRLVVLPEVISCMTKLVTLWLDNNRIRYLPDSIVELSFLEELVLQGNQIAILPDDFGKLSKVNIWK-------IKDNPLIQPPYEVCMKGISYIAAYQKELAHSQ----PAVK 397 HSP 2 Score: 82.8037 bits (203), Expect = 8.877e-16 Identity = 67/225 (29.78%), Postives = 107/225 (47.56%), Query Frame = 2
Query: 176 NLLDLEVLDMSPEREAGLYYKLQEVP-----LSIGKLLNLKILML----------------------------------------------DTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDN-MFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLL 694
+L D+EVL++ L+EVP LS G NL +L+L N LR +P+++G+L +LE + +S N +T LP+ ++ L LR+L + +N+ +FP+ + + ++E D S N M S+P+ IR+++SL+ L L L LPD +CEL+ + L L NN L LP+ FG L+ L
Sbjct: 51 DLGDVEVLNLGNN-------SLEEVPDGLQSLSAG---NLHVLILRRNKFLNVPTAVYHLGRLTELDISYNRLSCLTEAVGLLGKLKKLCLSHNQLRTLPRQLGMLVDLEELDVSFNQITHLPDTMQGLPSLRTLDLDHNELCSFPQQLFHVPALEELDFSGNKMLGSLPEGIRSMQSLKILWLSSTSLCLLPDSICELVNLESLMLDNNNLHTLPEGFGALQKL 265 HSP 3 Score: 58.151 bits (139), Expect = 7.729e-8 Identity = 41/147 (27.89%), Postives = 71/147 (48.30%), Query Frame = 2
Query: 263 GKLLNLKILMLDTNDLRHVPKEIGLLT--NLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLD 697
L ++++L L N L VP + L+ NL + L N +P + +L +L L I+ N+ E + + ++ S N R++P+ + L LE L + NQ+ LPD + L +R L L +N+L P+Q + L+
Sbjct: 50 ADLGDVEVLNLGNNSLEEVPDGLQSLSAGNLHVLILRRNKFLNVPTAVYHLGRLTELDISYNRLSCLTEAVGLLGKLKKLCLSHNQLRTLPRQLGMLVDLEELDVSFNQITHLPDTMQGLPSLRTLDLDHNELCSFPQQLFHVPALE 196
BLAST of Leucine-rich repeat-containing protein 57 vs. UniProt/SwissProt
Match: sp|Q9Y4C4|MFHA1_HUMAN (Malignant fibrous histiocytoma-amplified sequence 1 OS=Homo sapiens OX=9606 GN=MFHAS1 PE=1 SV=2) HSP 1 Score: 112.849 bits (281), Expect = 8.286e-26 Identity = 81/243 (33.33%), Postives = 117/243 (48.15%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLD-WSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFKKMYGSSVVEVPAAK 844
++ L + L++ P +L L+ LE LD+S R GL P I L LKIL L +L +P L +LE + L NN L LP + L++L+ L++++N FE FP + + +E S N SVP I L L TL L N++ LPD + EL + L L N++ LP FG+L + W + NPL PP ++C KG I Y K++ S P K
Sbjct: 183 LRTLDVDHNQLTAFPRQLLQLVALEELDVSSNRLRGL-------PEDISALRALKILWLSGAELGTLPAGFCELASLESLMLDNNGLQALPAQFSCLQRLKMLNLSSNLFEEFPAALLPLAGLEELYLSRNQLTSVPSLISGLGRLLTLWLDNNRIRYLPDSIVELTGLEELVLQGNQIAVLPDHFGQLSRVGLWK-------IKDNPLIQPPYEVCMKGIPYIAAYQKELAHSQPAVQPRLK 411 HSP 2 Score: 96.6709 bits (239), Expect = 2.186e-20 Identity = 65/199 (32.66%), Postives = 104/199 (52.26%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNL-LDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFG---RLKLLDWS 703
++ L L+ + +PP + L L LD+S R L ++ + L L+ L L N L +P ++G L +LE + +S N L LP+ + L +LR+L + +N+ FP + +++++E D S N R +P+ I L++L+ L L +L LP CEL + L L NN L LP QF RLK+L+ S
Sbjct: 89 LRVLVLRRNRFARLPPAVAELGHHLTELDVSHNRLTALGAEV------VSALRELRKLNLSHNQLPALPAQLGALAHLEELDVSFNRLAHLPDSLSCLSRLRTLDVDHNQLTAFPRQLLQLVALEELDVSSNRLRGLPEDISALRALKILWLSGAELGTLPAGFCELASLESLMLDNNGLQALPAQFSCLQRLKMLNLS 281
BLAST of Leucine-rich repeat-containing protein 57 vs. UniProt/SwissProt
Match: sp|Q7XK44|PIRL3_ORYSJ (Plant intracellular Ras-group-related LRR protein 3 OS=Oryza sativa subsp. japonica OX=39947 GN=IRL3 PE=2 SV=3) HSP 1 Score: 110.923 bits (276), Expect = 9.677e-26 Identity = 84/250 (33.60%), Postives = 122/250 (48.80%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNLLDLEVLDMS-------PEREAGLYY---------KLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIK-NLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYEN--QLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFKKMY 811
++ ++L + L +P + L VLD+S P+ GL + L +P SIG LLNL+IL + +N LR +P I +L + S N L LP I L LR L + NK + P ICE+ S+ DA N +P +I L SLE L L N L+ LP +L+ +R L L NN++ LP FGRL L+ L+ NPL PP++I KG D +++Y + +
Sbjct: 141 VESVRLVDRQLRHLPEAFGRIQGLRVLDVSRNQLEVIPDAIGGLDHLEELRLASNALISLPDSIGLLLNLRILNVGSNRLRSLPDSISKCRSLIELDASYNGLAYLPTNIGYELVNLRKLWVHMNKLRSLPSSICEMRSLYLLDAHFNELCGLPSAIGKLSSLEILNLSSNFSDLKDLPASFGDLLNLRELDLSNNQIHALPDNFGRLDKLE------KLNLEQNPLSMPPMEIVNKGVDAVKEYMLQRW 384 HSP 2 Score: 54.6842 bits (130), Expect = 6.530e-7 Identity = 29/95 (30.53%), Postives = 45/95 (47.37%), Query Frame = 2
Query: 410 KKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLL 694
K + S+ + + + PE I + D S N +P +I L LE L L N L LPD + L+ +R L +G+N+L LP + + L
Sbjct: 139 KPVESVRLVDRQLRHLPEAFGRIQGLRVLDVSRNQLEVIPDAIGGLDHLEELRLASNALISLPDSIGLLLNLRILNVGSNRLRSLPDSISKCRSL 233
BLAST of Leucine-rich repeat-containing protein 57 vs. UniProt/SwissProt
Match: sp|Q8W4Q3|PIRL3_ARATH (Plant intracellular Ras-group-related LRR protein 3 OS=Arabidopsis thaliana OX=3702 GN=PIRL3 PE=2 SV=1) HSP 1 Score: 110.153 bits (274), Expect = 2.411e-25 Identity = 86/265 (32.45%), Postives = 131/265 (49.43%), Query Frame = 2
Query: 110 FYGMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIK-NLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYEN--QLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFKKMYGS--------SVVEVPAAKGGTSNTLNF 871
G+ L + +L +P + L LE LD+S R L +P SIG LLNL+IL + N L +P+ I +L + S N+LT+LP L L L I NK FP ICE+ S+ + DA N +P +I L +LE + L N L LPD + +L +R L L NN++ LP F RL+ L+ LD NPL++PP ++ + A+ + ++ +K + SV+E +GG + L++
Sbjct: 183 IVGLVSLNVSRNNLRFLPDTISGLEKLEELDLSSNR-------LVFLPDSIGLLLNLRILNVTGNKLTLLPESIAQCRSLVELDASFNNLTSLPANFGYGLLNLERLSIQLNKIRFFPNSICEMRSLRYLDAHMNEIHGLPIAIGRLTNLEVMNLSSNFSDLIELPDTISDLANLRELDLSNNQIRVLPDSFFRLEKLE------KLNLDQNPLEYPPQEMVNQSAEAVREFMRKRWEEMVEEEQLRSVIEAEKQQGGATGWLSW 434 HSP 2 Score: 53.5286 bits (127), Expect = 1.575e-6 Identity = 48/158 (30.38%), Postives = 71/158 (44.94%), Query Frame = 2
Query: 212 EREAGLYYKLQEVPLSIGKLLNLKILML--DTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFG 679
E E G Y LS G +N ++L + D D V ERI LS++ L LP+ + + L SL+++ N P+ I + +E D S N +P SI L +L L + N+L LP+ + + + L N LT LP FG
Sbjct: 126 EEEIGRVYASAVESLSGGDEVNEEVLAVIKDAEDGGVV----------ERIDLSDHELKLLPDALGKIVGLVSLNVSRNNLRFLPDTISGLEKLEELDLSSNRLVFLPDSIGLLLNLRILNVTGNKLTLLPESIAQCRSLVELDASFNNLTSLPANFG 273
BLAST of Leucine-rich repeat-containing protein 57 vs. TrEMBL
Match: A0A1I8GSS0 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 361.688 bits (927), Expect = 7.882e-121 Identity = 174/259 (67.18%), Postives = 212/259 (81.85%), Query Frame = 2
Query: 47 PAMADKKNKSLRMMVDTEDPLFYGMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFKKMYGSSV 823
P++A + SLRMM+DTEDPLF GMKKLK+QG++L++VPPELFNL +LEVLDMSPEREA LYYKL +VP +I KL NL+IL+LDTNDL VP EIGLL NLER+ALSNN L++LP EI +L +L+S+H+ANNKF FP + MEF D SDNM + VPK+IR L +LETLM++ NQL GLPDE+C+L+Q+RC+WLG NK+ LPK FGRLKLLDWSWHYTST L+ NPL HPPL+ICK+GADEIE+YF M GSS
Sbjct: 13 PSIA-PGSSSLRMMIDTEDPLFQGMKKLKIQGRNLTAVPPELFNLSELEVLDMSPEREACLYYKLADVPTAICKLKNLRILLLDTNDLAKVPGEIGLLENLERLALSNNWLSSLPPEIGDLTQLKSIHLANNKFVHFPAAVLRCTQMEFLDISDNMLQKVPKAIRRLTNLETLMVFSNQLRGLPDEICDLVQLRCVWLGFNKVANLPKNFGRLKLLDWSWHYTSTILNENPLVHPPLEICKQGADEIERYF-AMLGSSA 269
BLAST of Leucine-rich repeat-containing protein 57 vs. TrEMBL
Match: A0A267EUA1 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig021248g2 PE=4 SV=1) HSP 1 Score: 362.459 bits (929), Expect = 2.894e-120 Identity = 174/259 (67.18%), Postives = 212/259 (81.85%), Query Frame = 2
Query: 47 PAMADKKNKSLRMMVDTEDPLFYGMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFKKMYGSSV 823
P++A + SLRMM+DTEDPLF GMKKLK+QG++L++VPPELFNL +LEVLDMSPEREA LYYKL +VP +I KL NL+IL+LDTNDL VP EIGLL NLER+ALSNN L++LP EI +L +L+S+H+ANNKF FP + MEF D SDNM + VPK+IR L +LETLM++ NQL GLPDE+C+L+Q+RC+WLG NK+ LPK FGRLKLLDWSWHYTST L+ NPL HPPL+ICK+GADEIE+YF M GSS
Sbjct: 39 PSIA-PGSSSLRMMIDTEDPLFQGMKKLKIQGRNLTAVPPELFNLSELEVLDMSPEREACLYYKLADVPTAICKLKNLRILLLDTNDLAKVPGEIGLLENLERLALSNNWLSSLPPEIGDLTQLKSIHLANNKFVHFPAAVLRCTQMEFLDISDNMLQKVPKAIRRLTNLETLMVFSNQLRGLPDEICDLVQLRCVWLGFNKVANLPKNFGRLKLLDWSWHYTSTILNENPLVHPPLEICKQGADEIERYF-AMLGSSA 295
BLAST of Leucine-rich repeat-containing protein 57 vs. TrEMBL
Match: A0A1I8ITE1 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig021248g5 PE=4 SV=1) HSP 1 Score: 360.918 bits (925), Expect = 4.457e-120 Identity = 173/259 (66.80%), Postives = 212/259 (81.85%), Query Frame = 2
Query: 47 PAMADKKNKSLRMMVDTEDPLFYGMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFKKMYGSSV 823
P++A + SLRMM+DTEDPLF GMKKLK+QG++L++VPPELFNL +LEVLDMSPEREA LYYKL +VP +I KL NL+IL+LDTNDL VP EIGLL NLER+ALSNN L++LP EI +L +L+S+H+ANNKF FP + +EF D SDNM + VPK+IR L +LETLM++ NQL GLPDE+C+L+Q+RC+WLG NK+ LPK FGRLKLLDWSWHYTST L+ NPL HPPL+ICK+GADEIE+YF M GSS
Sbjct: 13 PSIA-PGSSSLRMMIDTEDPLFQGMKKLKIQGRNLTAVPPELFNLSELEVLDMSPEREACLYYKLADVPTAICKLKNLRILLLDTNDLAKVPGEIGLLENLERLALSNNWLSSLPPEIGDLTQLKSIHLANNKFVHFPAAVLRCTQLEFLDISDNMLQKVPKAIRRLTNLETLMVFSNQLRGLPDEICDLVQLRCVWLGFNKVANLPKNFGRLKLLDWSWHYTSTILNENPLVHPPLEICKQGADEIERYF-AMLGSSA 269
BLAST of Leucine-rich repeat-containing protein 57 vs. TrEMBL
Match: A0A267DLM6 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig021248g7 PE=4 SV=1) HSP 1 Score: 362.073 bits (928), Expect = 5.391e-120 Identity = 174/259 (67.18%), Postives = 212/259 (81.85%), Query Frame = 2
Query: 47 PAMADKKNKSLRMMVDTEDPLFYGMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFKKMYGSSV 823
P++A + SLRMM+DTEDPLF GMKKLK+QG++L++VPPELFNL +LEVLDMSPEREA LYYKL +VP +I KL NL+IL+LDTNDL VP EIGLL NLER+ALSNN L++LP EI +L +L+S+H+ANNKF FP + MEF D SDNM + VPK+IR L +LETLM++ NQL GLPDE+C+L+Q+RC+WLG NK+ LPK FGRLKLLDWSWHYTST L+ NPL HPPL+ICK+GADEIE+YF M GSS
Sbjct: 45 PSIA-PGSSSLRMMIDTEDPLFQGMKKLKIQGRNLTAVPPELFNLSELEVLDMSPEREACLYYKLADVPTAICKLKNLRILLLDTNDLAKVPGEIGLLENLERLALSNNWLSSLPPEIGDLTQLKSIHLANNKFVHFPAAVLRCTQMEFLDISDNMLQKVPKAIRRLTNLETLMVFSNQLRGLPDEICDLVQLRCVWLGFNKVANLPKNFGRLKLLDWSWHYTSTILNENPLVHPPLEICKQGADEIERYF-AMLGSSA 301
BLAST of Leucine-rich repeat-containing protein 57 vs. TrEMBL
Match: A0A1I8HV29 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 345.51 bits (885), Expect = 1.771e-114 Identity = 170/259 (65.64%), Postives = 207/259 (79.92%), Query Frame = 2
Query: 47 PAMADKKNKSLRMMVDTEDPLFYGMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFKKMYGSSV 823
P++A + SLRMM+DTEDPLF GMKKLK+QG++L++VPPELFNL +LEVLDMSPEREA LYYKL +VP +I KL NL+IL+LDTNDL VP EIGLL NLER+ALSNN L++LP EI +L +L+S+H+ANNKF FP + MEF D SDNM + VPK+IR L +LETLM++ NQL GLPDE+C+L+Q+RC+WLG NK+ LPK FGRLKLLDWSWHYTST L+ NPL ICK+GADEIE+YF M GSS
Sbjct: 13 PSIA-PGSSSLRMMIDTEDPLFQGMKKLKIQGRNLTAVPPELFNLSELEVLDMSPEREACLYYKLADVPTAICKLKNLRILLLDTNDLAKVPGEIGLLENLERLALSNNWLSSLPPEIGDLTQLKSIHLANNKFVHFPAAVLRCTQMEFLDISDNMLQKVPKAIRRLTNLETLMVFSNQLRGLPDEICDLVQLRCVWLGFNKVANLPKNFGRLKLLDWSWHYTSTILNENPL------ICKQGADEIERYF-AMLGSSA 263
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Cavefish
Match: mfhas1 (malignant fibrous histiocytoma amplified sequence 1 [Source:ZFIN;Acc:ZDB-GENE-080917-20]) HSP 1 Score: 107.842 bits (268), Expect = 4.689e-25 Identity = 80/243 (32.92%), Postives = 125/243 (51.44%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLD-WSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFKKMYGSSVVEVPAAK 844
++ L + L PPE+ L DLE LD S KL+ +P +I L ++KIL L + + +P+ L NLE + L NN LT LP L++L+ L++++N FE FP+++ +I +E S N +P+ + L +L L L N++ LPD + EL ++ L L N++ LP FG+L ++ W + NPL PP ++C KG I Y K++ S PA K
Sbjct: 167 LRTLDVDHNKLQHFPPEVLALSDLEELDCSGN-------KLEGLPGNIMMLQSIKILWLSSTHIVSLPETFSDLQNLESLMLDNNLLTALPQSFGKLQRLKMLNLSSNSFEDFPQVVLKIARLEELYLSRNQLSFLPEEVGLLSNLANLWLDNNRITFLPDSIVELEKLEELVLQGNQIAILPDNFGKLAKVNIWK-------VKDNPLIQPPYEVCMKGIPYIAAYQKELAHSQ----PAVK 391 HSP 2 Score: 92.0485 bits (227), Expect = 7.256e-20 Identity = 63/198 (31.82%), Postives = 101/198 (51.01%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFG---RLKLLDWS 703
++ L L+ ++VP +F L L LD+S + L+ I L LK L + N ++++P +IG L LE + +S N L P L++LR+L + +NK + FP + + +E D S N +P +I L+S++ L L + LP+ +L + L L NN LT LP+ FG RLK+L+ S
Sbjct: 75 LRILILRRNKFAAVPSAVFQLSQLVELDLS-------HNCLKHFSEDIDLLKGLKKLCISHNKIQYLPSQIGTLQCLEELDISFNELHDFPRSFSQLRRLRTLDVDHNKLQHFPPEVLALSDLEELDCSGNKLEGLPGNIMMLQSIKILWLSSTHIVSLPETFSDLQNLESLMLDNNLLTALPQSFGKLQRLKMLNLS 265 HSP 3 Score: 81.2629 bits (199), Expect = 2.495e-16 Identity = 54/173 (31.21%), Postives = 85/173 (49.13%), Query Frame = 2
Query: 236 KLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPP 754
K VP ++ +L L L L N L+H ++I LL L+++ +S+N + LP++I L+ L L I+ N+ FP ++ + D N + P + L LE L N+LEGLP + L ++ LWL + + LP+ F L+ L+ S LD N L P
Sbjct: 84 KFAAVPSAVFQLSQLVELDLSHNCLKHFSEDIDLLKGLKKLCISHNKIQYLPSQIGTLQCLEELDISFNELHDFPRSFSQLRRLRTLDVDHNKLQHFPPEVLALSDLEELDCSGNKLEGLPGNIMMLQSIKILWLSSTHIVSLPETFSDLQNLE------SLMLDNNLLTALP 250 HSP 4 Score: 72.4034 bits (176), Expect = 2.232e-13 Identity = 52/157 (33.12%), Postives = 76/157 (48.41%), Query Frame = 2
Query: 239 LQEVPLSIGKLLN-LKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSW 706
LQE+P +G L L+IL+L N VP + L+ L + LS+N L +I LK L+ L I++NK + P I + +E D S N P+S L+ L TL + N+L+ P E+ L + L NKL LP L+ + W
Sbjct: 61 LQELPEGLGSTLTRLRILILRRNKFAAVPSAVFQLSQLVELDLSHNCLKHFSEDIDLLKGLKKLCISHNKIQYLPSQIGTLQCLEELDISFNELHDFPRSFSQLRRLRTLDVDHNKLQHFPPEVLALSDLEELDCSGNKLEGLPGNIMMLQSIKILW 217
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Cavefish
Match: LRRC2 (leucine rich repeat containing 2 [Source:NCBI gene;Acc:103036599]) HSP 1 Score: 99.3673 bits (246), Expect = 9.000e-23 Identity = 61/187 (32.62%), Postives = 108/187 (57.75%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALS-NNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQF 676
+++ ++G + VP + +DL VLD+ P+ + +P IGKL+NLK L ++ N L +P E+G NLE++ ++ N L+ LP E+ NLK L+ L +A NKF T P + + S+++ D S+N +P+ I L L+T+ L++N+L LP + + +++ L + ++LT LP +
Sbjct: 157 LREWHIRGTSIQKVPTYIEEFVDLRVLDI-PKNGFTM------LPPEIGKLVNLKELNVNYNKLSIIPPELGECENLEKLEMTANGDLSELPFELSNLKALKHLDLAENKFATIPICVLRMSSLQWLDMSNNRLTDLPEDIDRLSDLQTMFLHKNKLTYLPMVMANMDKLKMLVVSGDELTNLPSKL 336 HSP 2 Score: 56.6102 bits (135), Expect = 1.492e-8 Identity = 40/155 (25.81%), Postives = 78/155 (50.32%), Query Frame = 2
Query: 116 GMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYEN 580
+K+L + LS +PPEL +LE L+M+ + L E+P + L LK L L N +P + +++L+ + +SNN LT LP +I L L+++ + NK P ++ + ++ S + ++P + + ++ + L++N
Sbjct: 202 NLKELNVNYNKLSIIPPELGECENLEKLEMTANGD------LSELPFELSNLKALKHLDLAENKFATIPICVLRMSSLQWLDMSNNRLTDLPEDIDRLSDLQTMFLHKNKLTYLPMVMANMDKLKMLVVSGDELTNLPSKLCDSPDIKFIKLFDN 350 HSP 3 Score: 56.6102 bits (135), Expect = 1.547e-8 Identity = 42/149 (28.19%), Postives = 74/149 (49.66%), Query Frame = 2
Query: 239 LQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRL 685
+Q+VP I + ++L++L + N +P EIG L NL+ + ++ N L+ +P E+ + L L + N D S+ +P + NLK+L+ L L EN+ +P + + ++ L + NN+LT LP+ RL
Sbjct: 167 IQKVPTYIEEFVDLRVLDIPKNGFTMLPPEIGKLVNLKELNVNYNKLSIIPPELGECENLEKLEMTANG-----------------DLSE-----LPFELSNLKALKHLDLAENKFATIPICVLRMSSLQWLDMSNNRLTDLPEDIDRL 293
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Cavefish
Match: LRRC2 (leucine rich repeat containing 2 [Source:NCBI gene;Acc:103036599]) HSP 1 Score: 98.9821 bits (245), Expect = 1.000e-22 Identity = 61/187 (32.62%), Postives = 108/187 (57.75%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALS-NNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQF 676
+++ ++G + VP + +DL VLD+ P+ + +P IGKL+NLK L ++ N L +P E+G NLE++ ++ N L+ LP E+ NLK L+ L +A NKF T P + + S+++ D S+N +P+ I L L+T+ L++N+L LP + + +++ L + ++LT LP +
Sbjct: 157 LREWHIRGTSIQKVPTYIEEFVDLRVLDI-PKNGFTM------LPPEIGKLVNLKELNVNYNKLSIIPPELGECENLEKLEMTANGDLSELPFELSNLKALKHLDLAENKFATIPICVLRMSSLQWLDMSNNRLTDLPEDIDRLSDLQTMFLHKNKLTYLPMVMANMDKLKMLVVSGDELTNLPSKL 336 HSP 2 Score: 56.6102 bits (135), Expect = 1.517e-8 Identity = 42/149 (28.19%), Postives = 74/149 (49.66%), Query Frame = 2
Query: 239 LQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRL 685
+Q+VP I + ++L++L + N +P EIG L NL+ + ++ N L+ +P E+ + L L + N D S+ +P + NLK+L+ L L EN+ +P + + ++ L + NN+LT LP+ RL
Sbjct: 167 IQKVPTYIEEFVDLRVLDIPKNGFTMLPPEIGKLVNLKELNVNYNKLSIIPPELGECENLEKLEMTANG-----------------DLSE-----LPFELSNLKALKHLDLAENKFATIPICVLRMSSLQWLDMSNNRLTDLPEDIDRL 293 HSP 3 Score: 56.6102 bits (135), Expect = 1.572e-8 Identity = 40/155 (25.81%), Postives = 78/155 (50.32%), Query Frame = 2
Query: 116 GMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYEN 580
+K+L + LS +PPEL +LE L+M+ + L E+P + L LK L L N +P + +++L+ + +SNN LT LP +I L L+++ + NK P ++ + ++ S + ++P + + ++ + L++N
Sbjct: 202 NLKELNVNYNKLSIIPPELGECENLEKLEMTANGD------LSELPFELSNLKALKHLDLAENKFATIPICVLRMSSLQWLDMSNNRLTDLPEDIDRLSDLQTMFLHKNKLTYLPMVMANMDKLKMLVVSGDELTNLPSKLCDSPDIKFIKLFDN 350
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Cavefish
Match: LRRC2 (leucine rich repeat containing 2 [Source:NCBI gene;Acc:103036599]) HSP 1 Score: 99.3673 bits (246), Expect = 1.077e-22 Identity = 61/186 (32.80%), Postives = 108/186 (58.06%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALS-NNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQ 673
+++ ++G + VP + +DL VLD+ P+ + +P IGKL+NLK L ++ N L +P E+G NLE++ ++ N L+ LP E+ NLK L+ L +A NKF T P + + S+++ D S+N +P+ I L L+T+ L++N+L LP + + +++ L + ++LT LP +
Sbjct: 194 LREWHIRGTSIQKVPTYIEEFVDLRVLDI-PKNGFTM------LPPEIGKLVNLKELNVNYNKLSIIPPELGECENLEKLEMTANGDLSELPFELSNLKALKHLDLAENKFATIPICVLRMSSLQWLDMSNNRLTDLPEDIDRLSDLQTMFLHKNKLTYLPMVMANMDKLKMLVVSGDELTNLPSK 372 HSP 2 Score: 57.3806 bits (137), Expect = 8.995e-9 Identity = 42/149 (28.19%), Postives = 74/149 (49.66%), Query Frame = 2
Query: 239 LQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRL 685
+Q+VP I + ++L++L + N +P EIG L NL+ + ++ N L+ +P E+ + L L + N D S+ +P + NLK+L+ L L EN+ +P + + ++ L + NN+LT LP+ RL
Sbjct: 204 IQKVPTYIEEFVDLRVLDIPKNGFTMLPPEIGKLVNLKELNVNYNKLSIIPPELGECENLEKLEMTANG-----------------DLSE-----LPFELSNLKALKHLDLAENKFATIPICVLRMSSLQWLDMSNNRLTDLPEDIDRL 330 HSP 3 Score: 56.9954 bits (136), Expect = 1.332e-8 Identity = 40/155 (25.81%), Postives = 78/155 (50.32%), Query Frame = 2
Query: 116 GMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYEN 580
+K+L + LS +PPEL +LE L+M+ + L E+P + L LK L L N +P + +++L+ + +SNN LT LP +I L L+++ + NK P ++ + ++ S + ++P + + ++ + L++N
Sbjct: 239 NLKELNVNYNKLSIIPPELGECENLEKLEMTANGD------LSELPFELSNLKALKHLDLAENKFATIPICVLRMSSLQWLDMSNNRLTDLPEDIDRLSDLQTMFLHKNKLTYLPMVMANMDKLKMLVVSGDELTNLPSKLCDSPDIKFIKLFDN 387
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Cavefish
Match: lrrc7 (leucine rich repeat containing 7 [Source:ZFIN;Acc:ZDB-GENE-130530-876]) HSP 1 Score: 99.3673 bits (246), Expect = 2.869e-22 Identity = 61/199 (30.65%), Postives = 105/199 (52.76%), Query Frame = 2
Query: 110 FYGMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSW 706
+ +K+L L L ++P + L L LD++ R ++ + I +L+ L+L +N L+ +P IG+L L + + +N LT+LPN I +L L + N+ E+ P I + S+ F A +N +P+ I N +++ + L N+LE LPDE+ ++ ++R L L +N+L LP F +LK L W
Sbjct: 174 IHNLKELWLDNNSLQTIPGSIGKLRQLRYLDLAKNR-------IESLDADISGCESLEDLLLSSNMLQQLPDTIGMLKKLTTLKVDDNQLTSLPNTIGSLSLLEEFDCSCNELESLPPTIGYLHSLRTFAADENFLTELPREIGNCRNVTVMSLRSNKLEFLPDEIGQMTKLRVLNLSDNRLRNLPYTFTKLKDLAALW 365 HSP 2 Score: 78.5666 bits (192), Expect = 2.237e-15 Identity = 60/203 (29.56%), Postives = 99/203 (48.77%), Query Frame = 2
Query: 116 GMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLH---------IANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLD 697
++KL + DLSS+P + +L++L+ LD+S +QE P +I L ++ N + +P L NL ++ L++ L LP L KL+ L + NN +T P I ++ + + D + N S+ I +SLE L+L N L+ LPD + L ++ L + +N+LT LP G L LL+
Sbjct: 75 ALRKLSIPDNDLSSLPTTIASLVNLKELDIS-------KNGIQEFPDNIKCCKCLSVVEASVNPITKLPDGFTQLLNLTQLFLNDAFLEYLPANFGRLSKLQVLEQIHNLKELWLDNNSLQTIPGSIGKLRQLRYLDLAKNRIESLDADISGCESLEDLLLSSNMLQQLPDTIGMLKKLTTLKVDDNQLTSLPNTIGSLSLLE 270 HSP 3 Score: 70.0922 bits (170), Expect = 1.165e-12 Identity = 56/183 (30.60%), Postives = 89/183 (48.63%), Query Frame = 2
Query: 188 LEVLDMSPEREAGLYYKLQEVPLSIGKL-LNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEII--CEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRC---------LWLGNNKLTQLPKQFGRLKLLDW 700
+ VLD S + LQ+VP I L+ L LD N + +PK++ L ++++ +N L++LP I +L L+ L I+ N + FP+ I C+ LS+ +AS N +P L +L L L + LE LP L +++ LWL NN L +P G+L+ L +
Sbjct: 29 ISVLDYS-------HCSLQQVPKEIFSFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSSLPTTIASLVNLKELDISKNGIQEFPDNIKCCKCLSV--VEASVNPITKLPDGFTQLLNLTQLFLNDAFLEYLPANFGRLSKLQVLEQIHNLKELWLDNNSLQTIPGSIGKLRQLRY 202 HSP 4 Score: 70.0922 bits (170), Expect = 1.470e-12 Identity = 50/158 (31.65%), Postives = 77/158 (48.73%), Query Frame = 2
Query: 308 LRHVPKEI-GLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGR---LKLLDWSWHYTSTTLDGNPLQHPPLDICK 769
L+ VPKEI LE + L N + LP ++ N + LR L I +N + P I +++++ D S N + P +I+ K L + N + LPD +L+ + L+L + L LP FGR L++L+ + LD N LQ P I K
Sbjct: 39 LQQVPKEIFSFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSSLPTTIASLVNLKELDISKNGIQEFPDNIKCCKCLSVVEASVNPITKLPDGFTQLLNLTQLFLNDAFLEYLPANFGRLSKLQVLEQIHNLKELWLDNNSLQTIPGSIGK 196
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000011353.1 (pep scaffold:Pmarinus_7.0:GL480086:13034:13672:1 gene:ENSPMAG00000010326.1 transcript:ENSPMAT00000011353.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 215.312 bits (547), Expect = 3.095e-69 Identity = 100/210 (47.62%), Postives = 146/210 (69.52%), Query Frame = 2
Query: 176 NLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKF-ETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFK 802
+L +LEVLD+SPERE+ ++Y L+ +P + +L NL++L LDTN+LR +P E+ LL NLER++LSNN+LT LP + L+KLRS+H+ANNK P +C++ ++ F DASDN +P +I ++ LETL+L N + LPDELC L +R LWLG+N+L LP+ FG L+ L W + +DGNP+ PPLD+C++G + I +YF
Sbjct: 1 SLSELEVLDLSPERESCIHYTLRSLPADVCRLHNLRVLCLDTNELRELPSEVSLLANLERVSLSNNALTALPRGLGGLRKLRSVHLANNKLGPVLPAELCQLKALCFLDASDNCIERLPSAIGSMAKLETLLLLYNSIRELPDELCSLTTLRTLWLGSNRLRSLPRGFGELRGLRWG--SSGADVDGNPMAEPPLDVCRRGVEAIGRYFA 208
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Sea Lamprey
Match: lrch3 (leucine-rich repeats and calponin homology (CH) domain containing 3 [Source:ZFIN;Acc:ZDB-GENE-071004-44]) HSP 1 Score: 90.1225 bits (222), Expect = 1.229e-20 Identity = 60/185 (32.43%), Postives = 91/185 (49.19%), Query Frame = 2
Query: 293 LDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKL--LDWSW--------------HYTSTTLDGNPLQHPPLDICKKGADEIEKYF 799
L N L VP E+ +LE + L +N + ++P I NL+ L L+I+ N+ T P +C+ L ++ +AS+N S+P+ + LK L L + N+++ LP ++ L +R L + N L LP + L L LD S S LD NP++ PP IC KG I KY
Sbjct: 5 LSKNRLNEVPLEVCHFVSLESLVLYHNCIRSIPEAIVNLRSLTYLNISRNQLTTLPPYLCK-LPLQVLNASNNKLVSLPEELGQLKELSALDVSCNEIQALPPQVASLTCLRDLNVRRNNLVILPDEIADLPLVQLDVSCNRLGEIPVSFRKLKQLQSLVLDNNPMKSPPAQICIKGKHHIFKYL 188 HSP 2 Score: 66.2402 bits (160), Expect = 1.961e-12 Identity = 48/167 (28.74%), Postives = 82/167 (49.10%), Query Frame = 2
Query: 110 FYGMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELC 610
F ++ L L + S+P + NL L L++S + L L ++P L++L N L +P+E+G L L + +S N + LP ++ +L LR L++ N P+ I + L + D S N +P S R LK L++L+L N ++ P ++C
Sbjct: 20 FVSLESLVLYHNCIRSIPEAIVNLRSLTYLNISRNQLTTLPPYLCKLP--------LQVLNASNNKLVSLPEELGQLKELSALDVSCNEIQALPPQVASLTCLRDLNVRRNNLVILPDEIAD-LPLVQLDVSCNRLGEIPVSFRKLKQLQSLVLDNNPMKSPPAQIC 177
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Sea Lamprey
Match: scrib (scribble planar cell polarity protein [Source:NCBI gene;Acc:368473]) HSP 1 Score: 92.0485 bits (227), Expect = 1.550e-20 Identity = 61/195 (31.28%), Postives = 103/195 (52.82%), Query Frame = 2
Query: 110 FYGMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLL 694
+ ++KL L +L +PP++ N + L LDMS + E+P SI L+++ N L +P+ L +L ++L++ SL LP++I NL L +L + N +T P + ++ +E D +N ++P S+ +L ++ L L NQLE LP E+ EL ++ CL + N+L +LP G L L
Sbjct: 5 LHNLRKLGLSDNELQRLPPDIANFMHLVDLDMS-------RNDIAEIPDSIKLCTCLEVVDFSGNPLTRLPEGFTQLKSLIYLSLNDVSLQGLPDDIGNLSNLVTLELRENLLKTLPTSLHLLVKLEQLDLGNNELETLPGSLGSLPNVRELWLDGNQLEALPSEIGELRRLVCLDISQNRLERLPDAIGGLAAL 192 HSP 2 Score: 91.6633 bits (226), Expect = 2.409e-20 Identity = 65/194 (33.51%), Postives = 94/194 (48.45%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNLLDLEVLDMS-------PEREAGLYY---------KLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNK 652
+++L L G L ++P E+ L L LD+S P+ GL L+E+P +GKL +L IL D N L H+P+ IG NL + L+ N L TLP I L KL +L++ N+ + P I ++ DN VP I + L L N+LE LP EL +L ++ LWL N+
Sbjct: 146 VRELWLDGNQLEALPSEIGELRRLVCLDISQNRLERLPDAIGGLAALTDFLASQNHLEELPEELGKLKHLSILKADQNRLTHLPEAIGDCENLTELILTENQLVTLPASIGKLTKLTNLNLDKNRLNSIPPEIGGCGALNVLSLRDNRLTQVPGEISGASQIHVLDLAGNRLENLPIELAKL-SLKALWLSENQ 338 HSP 3 Score: 85.5001 bits (210), Expect = 2.063e-18 Identity = 75/254 (29.53%), Postives = 119/254 (46.85%), Query Frame = 2
Query: 128 LKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFKKMYGSSVVEVPAAKGGTSNTLNFDVDAMR 889
L L L +P ++ NL +L L++ RE L+ +P S+ L+ L+ L L N+L +P +G L N+ + L N L LP+EI L++L L I+ N+ E P+ I + ++ F AS N +P+ + LK L L +N+L LP+ + + + L L N+L LP G+L L T+ LD N L P +I GA + + + + +VP G S D+ R
Sbjct: 80 LSLNDVSLQGLPDDIGNLSNLVTLEL---RE----NLLKTLPTSLHLLVKLEQLDLGNNELETLPGSLGSLPNVRELWLDGNQLEALPSEIGELRRLVCLDISQNRLERLPDAIGGLAALTDFLASQNHLEELPEELGKLKHLSILKADQNRLTHLPEAIGDCENLTELILTENQLVTLPASIGKLTKL------TNLNLDKNRLNSIPPEIGGCGALNV----LSLRDNRLTQVPGEISGASQIHVLDLAGNR 316 HSP 4 Score: 77.0258 bits (188), Expect = 1.393e-15 Identity = 54/166 (32.53%), Postives = 84/166 (50.60%), Query Frame = 2
Query: 266 KLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDI 763
+L NL+ L L N+L+ +P +I +L + +S N + +P+ IK L + + N PE ++ S+ + +D + +P I NL +L TL L EN L+ LP L L+++ L LGNN+L LP G L + W LDGN L+ P +I
Sbjct: 4 RLHNLRKLGLSDNELQRLPPDIANFMHLVDLDMSRNDIAEIPDSIKLCTCLEVVDFSGNPLTRLPEGFTQLKSLIYLSLNDVSLQGLPDDIGNLSNLVTLELRENLLKTLPTSLHLLVKLEQLDLGNNELETLPGSLGSLPNVRELW------LDGNQLEALPSEI 163
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004940.1 (pep scaffold:Pmarinus_7.0:GL476356:339323:347865:-1 gene:ENSPMAG00000004448.1 transcript:ENSPMAT00000004940.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 88.9669 bits (219), Expect = 1.307e-19 Identity = 68/191 (35.60%), Postives = 100/191 (52.36%), Query Frame = 2
Query: 236 KLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNN-KLTQLPKQFGRL-KLLDWSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFK 802
+L +PL IG ++ L L TN L +P +I LT+LE + LSNN L LP+ + NL+KLR L + NK E+ P I + ++ ++N S+P+ I +L SL LM+ ENQL +P+E+ L + L+L +N L LP + KLL S ++ PL P I G I +Y K
Sbjct: 339 QLTSLPLDIGTWKSMVELNLATNQLTKIPDDISELTSLEILVLSNNLLRKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTSLPRGIGHLCSLTHLMVGENQLTHVPEEIGTLENLEELYLNDNPNLHNLPFELALCSKLLIMS-------IENCPLSQLPGPIVSSGPSFIIQYLK 522 HSP 2 Score: 83.9593 bits (206), Expect = 5.417e-18 Identity = 60/192 (31.25%), Postives = 94/192 (48.96%), Query Frame = 2
Query: 95 TEDPLFYGMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPK 670
TE + L L L+ +P L L L +LD+ + KL+ +P + +L +L +L L N + V K+IG L+ L +++ N + LP EI L+ L +L +A+N+ E PE I + + D N +P SI NL SL L L N+L +P L ++ L L NN ++ LP+
Sbjct: 89 TEIGCLVNLVTLALNENSLTGLPDTLTGLTSLRMLDLR-------HNKLRSIPPVVYRLTSLTVLYLRFNRITQVEKDIGNLSKLTMLSVRENKIKLLPAEIGELRSLLTLDVAHNQLEHLPEEIGNCVQVTNLDLQHNELLDLPDSIGNLASLNRLGLRYNRLSAVPTTLANCTELEDLNLENNNISTLPE 273 HSP 3 Score: 79.7221 bits (195), Expect = 1.352e-16 Identity = 49/139 (35.25%), Postives = 76/139 (54.68%), Query Frame = 2
Query: 347 LERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDI 763
L ++ + +N LT+LP +I K + L++A N+ P+ I E+ S+E S+N+ R +P + NL+ L L L EN+LE LP+E+ L ++ L L NN+LT LP+ G L T + N L H P +I
Sbjct: 330 LSKLNMKDNQLTSLPLDIGTWKSMVELNLATNQLTKIPDDISELTSLEILVLSNNLLRKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTSLPRGIGHL------CSLTHLMVGENQLTHVPEEI 462 HSP 4 Score: 79.337 bits (194), Expect = 1.623e-16 Identity = 52/147 (35.37%), Postives = 79/147 (53.74%), Query Frame = 2
Query: 239 LQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFG 679
+ +P +I +L L L L N L +P EIG L NL +AL+ NSLT LP+ + L LR L + +NK + P ++ + S+ N V K I NL L L + EN+++ LP E+ EL + L + +N+L LP++ G
Sbjct: 61 IASLPPNIKELTQLTELYLYGNRLPCLPTEIGCLVNLVTLALNENSLTGLPDTLTGLTSLRMLDLRHNKLRSIPPVVYRLTSLTVLYLRFNRITQVEKDIGNLSKLTMLSVRENKIKLLPAEIGELRSLLTLDVAHNQLEHLPEEIG 207
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000011392.1 (pep scaffold:Pmarinus_7.0:GL489956:7319:8005:-1 gene:ENSPMAG00000010365.1 transcript:ENSPMAT00000011392.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 85.1149 bits (209), Expect = 1.597e-19 Identity = 62/211 (29.38%), Postives = 100/211 (47.39%), Query Frame = 2
Query: 224 GLYY-KLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKN-----------------------LKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRL-KLLDWSWHYTSTTLD--GNPLQHPPLDICKKG 775
GL+ +L +P + G+L NL +L LD N+L P EIG+L L+ + + N L +P E+ L+KLR L+++ N P + + ++ F D S N +P S+R L+ LETL+ N+LE LP +CE+ ++ L + N++ +P +L +L + H L NPL P + KG
Sbjct: 5 GLWRNRLTTMPSATGRLENLVVLGLDGNNLIAFPAEIGMLRKLKALFANRNRLVEVPRELAKCQSLEVLSLSSNSLRSLPDDLVALRKLRKLNLSANALGRVPRCVMYMKALTFLDVSYNDIVGLPDSVRELQRLETLIAERNRLEALPASICEITRLETLNVDYNQIRTVPLDLDQLVRLPRIANHPVDRGLHIRNNPLADPLAAVVDKG 215
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Yeast
Match: CYR1 (Adenylate cyclase; required for cAMP production and cAMP-dependent protein kinase signaling; the cAMP pathway controls a variety of cellular processes, including metabolism, cell cycle, stress response, stationary phase, and sporulation [Source:SGD;Acc:S000003542]) HSP 1 Score: 64.3142 bits (155), Expect = 1.489e-11 Identity = 49/153 (32.03%), Postives = 78/153 (50.98%), Query Frame = 2
Query: 236 KLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLL 694
+ + P +I K L L L N +R VP I L+NL + L N L +LP LK L+ L +++NKF +PE+I ++ D S N +S+P+S + L L + L N+L + D L E+ +R L L N+++ + L+ L
Sbjct: 851 RASKFPSNITKAYKLVSLELQRNFIRKVPNSIMKLSNLTILNLQCNELESLPAGFVELKNLQLLDLSSNKFMHYPEVINYCTNLLQIDLSYNKIQSLPQSTKYLVKLAKMNLSHNKLNFIGD-LSEMTDLRTLNLRYNRISSIKTNASNLQNL 1002 HSP 2 Score: 50.447 bits (119), Expect = 3.465e-7 Identity = 72/278 (25.90%), Postives = 110/278 (39.57%), Query Frame = 2
Query: 77 LRMMVDTEDPL-------FY--GMKKLKLQGKDLSSVPPELFNLLD-LEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFE------------TFPEIICEILSMEFFDASDNMFRSVP----------------------------KSIRNL------------------KSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSW 706
LR + E+P+ FY M L L LSS+P EL L LE L+++ L +P I KL L L + N L ++P E+ L +L + L +N++ + ++NL+ L SL+I++N F ++ + + S+ FF A+DN F +SI L SL+TLML NQ+ LP EL L Q+ +G N+L + DW+W
Sbjct: 1019 LRALEIQENPITSISFKDFYPKNMTSLTLNKAQLSSIPGELLTKLSFLEKLELNQN-------NLTRLPQEISKLTKLVFLSVARNKLEYIPPELSQLKSLRTLDLHSNNIRDFVDGMENLE-LTSLNISSNAFGNSSLENSFYHNMSYGSKLSK--SLMFFIAADNQFDDAMWPLFNCFVNLKVLNLSYNNFSDVSHMKLESITELYLSGNKLTTLSGDTVLKWSSLKTLMLNSNQMLSLPAELSNLSQLSVFDVGANQLKYNISNYH----YDWNW 1282 HSP 3 Score: 50.0618 bits (118), Expect = 4.742e-7 Identity = 62/257 (24.12%), Postives = 101/257 (39.30%), Query Frame = 2
Query: 113 YGMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIK------------------------------------------NLKKLRSLHIANNKFETFPEIICE----------ILSMEFFD-ASDNM---------FRSVPKSI-RNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLL 694
Y + L+LQ + VP + L +L +L++ +L+ +P +L NL++L L +N H P+ I TNL +I LS N + +LP K N L++L + +N+ F + + + I S+ F D NM S+P + L LE L L +N L LP E+ +L ++ L + NKL +P + +LK L
Sbjct: 863 YKLVSLELQRNFIRKVPNSIMKLSNLTILNLQCN-------ELESLPAGFVELKNLQLLDLSSNKFMHYPEVINYCTNLLQIDLSYNKIQSLPQSTKYLVKLAKMNLSHNKLNFIGDLSEMTDLRTLNLRYNRISSIKTNASNLQNLFLTDNRISNFEDTLPKLRALEIQENPITSISFKDFYPKNMTSLTLNKAQLSSIPGELLTKLSFLEKLELNQNNLTRLPQEISKLTKLVFLSVARNKLEYIPPELSQLKSL 1112
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Yeast
Match: SOG2 (Key component of the RAM signaling network; required for proper cell morphogenesis and cell separation after mitosis [Source:SGD;Acc:S000005880]) HSP 1 Score: 55.4546 bits (132), Expect = 6.243e-9 Identity = 40/147 (27.21%), Postives = 69/147 (46.94%), Query Frame = 2
Query: 278 LKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQ--MRCLWLGNNKLTQLPK-----QFGRLKLLD 697
LK++ L+ + +++G + N+ER++L N LT+LP K L +L+ L + NN F+ P I+ + +E D L N++E LPDE+ Q +R L L +N +T + + +L +LD
Sbjct: 47 LKLIALNIKSISD--EDVGYIQNVERLSLRKNHLTSLPASFKRLSRLQYLDLHNNNFKEIPYILTQCPQLEILD-----------------------LSSNEIEALPDEISSFWQDNIRVLSLKDNNVTSIRNLKSITKLNKLSILD 168
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Yeast
Match: CCR4 (Component of the CCR4-NOT transcriptional complex; CCR4-NOT is involved in regulation of gene expression; component of the major cytoplasmic deadenylase, which is involved in mRNA poly(A) tail shortening [Source:SGD;Acc:S000000019]) HSP 1 Score: 54.6842 bits (130), Expect = 1.177e-8 Identity = 31/81 (38.27%), Postives = 47/81 (58.02%), Query Frame = 2
Query: 347 LERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLE 589
L R+ L+ NSLT LP EIKNL LR L +++N+ + P + +++F DNM ++P NL +L+ L + N LE
Sbjct: 359 LTRLYLNGNSLTELPAEIKNLSNLRVLDLSHNRLTSLPAELGSCFQLKYFYFFDNMVTTLPWEFGNLCNLQFLGVEGNPLE 439
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Nematostella
Match: EDO43554 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RY02]) HSP 1 Score: 96.6709 bits (239), Expect = 5.532e-22 Identity = 69/217 (31.80%), Postives = 122/217 (56.22%), Query Frame = 2
Query: 74 SLRMMVDTEDPLFYGMKKL---KLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWL-----GNNKLTQLPKQFGRLKLLDW 700
S R+ V DP + + +L ++ L+ VP E+ NL++L LDM R A ++ +P +IGKL ++K + N L +P EIG + +L+ + L+ N+LTT+P ++N K L L I++N+ E+ PE I + + A++N+ +++ + L L+ L L EN+LE +P EL + ++++ L L +N+L +L KQ +LD+
Sbjct: 25 SERISVSGLDPAIFQLTRLNFLQISNTSLNHVPDEIGNLINLRTLDM--HRNA-----IKSIPSTIGKLKDVKAIDFSGNSLEKLPAEIGHMEHLQTLNLNCNALTTVP-PLRNAKNLARLDISHNRLESLPEGIFNLELIAEIYAANNLIQALGNEVGCLHVLKVLDLSENKLEAIPCELADCLKLKDLNLKENPIKDNRLGKLIKQCKTKAVLDY 233
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Nematostella
Match: EDO37227 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SGD7]) HSP 1 Score: 86.6557 bits (213), Expect = 7.679e-20 Identity = 55/167 (32.93%), Postives = 90/167 (53.89%), Query Frame = 2
Query: 173 FNLLDLEVLDMSPEREAGLYYKL-QEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPK 670
N+L + L + + L Y L +P I +L +LK L L +N+L H+P+EIG + LE + +S+N L LP I L+ L+ LHIANN+ + P + + ++ D +N +P + + LETL+ N +E LP +L +L ++ L N+L LP+
Sbjct: 27 LNVLPVSFLHLKKVQRVYLKYNLLTSLPQEISRLSSLKELYLHSNNLTHLPQEIGHIKCLESLNVSHNFLQNLPPTIGQLQHLQYLHIANNQLHSLPREVGHLKQLQVLDIMNNNLHQLPWQLSDCVRLETLLFDGNLVEWLPQQLTDLKGLKELSGSRNRLLSLPQ 193 HSP 2 Score: 83.5741 bits (205), Expect = 1.125e-18 Identity = 47/153 (30.72%), Postives = 87/153 (56.86%), Query Frame = 2
Query: 230 YYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLK 688
Y L +P+S L ++ + L N L +P+EI L++L+ + L +N+LT LP EI ++K L SL++++N + P I ++ +++ ++N S+P+ + +LK L+ L + N L LP +L + +++ L N + LP+Q LK
Sbjct: 24 YQHLNVLPVSFLHLKKVQRVYLKYNLLTSLPQEISRLSSLKELYLHSNNLTHLPQEIGHIKCLESLNVSHNFLQNLPPTIGQLQHLQYLHIANNQLHSLPREVGHLKQLQVLDIMNNNLHQLPWQLSDCVRLETLLFDGNLVEWLPQQLTDLK 176 HSP 3 Score: 74.7146 bits (182), Expect = 1.344e-15 Identity = 45/131 (34.35%), Postives = 69/131 (52.67%), Query Frame = 2
Query: 287 LMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFG 679
L L+ L +P L ++R+ L N LT+LP EI L L+ L++ +N P+ I I +E + S N +++P +I L+ L+ L + NQL LP E+ L Q++ L + NN L QLP Q
Sbjct: 20 LYLNYQHLNVLPVSFLHLKKVQRVYLKYNLLTSLPQEISRLSSLKELYLHSNNLTHLPQEIGHIKCLESLNVSHNFLQNLPPTIGQLQHLQYLHIANNQLHSLPREVGHLKQLQVLDIMNNNLHQLPWQLS 150 HSP 4 Score: 66.6254 bits (161), Expect = 9.627e-13 Identity = 51/189 (26.98%), Postives = 90/189 (47.62%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLP--------------DELCELIQMRCLWLG 643
++++ L+ L+S+P E+ L L+ L + L +P IG + L+ L + N L+++P IG L +L+ + ++NN L +LP E+ +LK+L+ L I NN P + + + +E N+ +P+ + +LK L+ L N+L LP +L E C W G
Sbjct: 40 VQRVYLKYNLLTSLPQEISRLSSLKELYLHSN-------NLTHLPQEIGHIKCLESLNVSHNFLQNLPPTIGQLQHLQYLHIANNQLHSLPREVGHLKQLQVLDIMNNNLHQLPWQLSDCVRLETLLFDGNLVEWLPQQLTDLKGLKELSGSRNRLLSLPQDQTLPAYSLPSSLSDLVEYPTAHCYWCG 221 HSP 5 Score: 56.225 bits (134), Expect = 3.276e-9 Identity = 34/118 (28.81%), Postives = 62/118 (52.54%), Query Frame = 2
Query: 344 NLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLD 697
N + L+ L LP +LKK++ +++ N + P+ I + S++ N +P+ I ++K LE+L + N L+ LP + +L ++ L + NN+L LP++ G LK L
Sbjct: 16 NHVNLYLNYQHLNVLPVSFLHLKKVQRVYLKYNLLTSLPQEISRLSSLKELYLHSNNLTHLPQEIGHIKCLESLNVSHNFLQNLPPTIGQLQHLQYLHIANNQLHSLPREVGHLKQLQ 133
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Nematostella
Match: EDO35138 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SMB5]) HSP 1 Score: 84.3445 bits (207), Expect = 7.583e-19 Identity = 59/206 (28.64%), Postives = 101/206 (49.03%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYY----------------KLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLK 688
+ +L L+ L +P ++ L+ LEVLD++ L Y ++ +P S+ + L L L+ N+L+ P+E+ L+ L + L++N+L LP K L LR L++ +NK P+ + + +N P I L SLE L+L N + LPD + EL+ ++ L+LG NK+ +LP +L+
Sbjct: 39 LTELYLRNDFLEFLPAQVCTLVQLEVLDLANNFIRTLPYSSGHLTRLRWLNLQNNQITNLPSSLADMNGLCYLNLEANELKIFPEEVSQLSRLRVLHLNSNNLRALPESFKLLNHLRILYLKDNKLRVLPDWFASFHCLAYLSMENNDLVCFPGEISKLTSLEVLILSGNSIRELPDSIKELVNLKELFLGRNKIRKLPPSITKLE 244 HSP 2 Score: 73.9442 bits (180), Expect = 3.792e-15 Identity = 57/218 (26.15%), Postives = 99/218 (45.41%), Query Frame = 2
Query: 149 LSSVPPELFNLLDLEVLDMSPEREAGLYYK----------------LQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPP 754
L P ++ L L+VL++S Y+ L+ +P + L+ L++L L N +R +P G LT L + L NN +T LP+ + ++ L L++ N+ + FPE + ++ + + N R++P+S + L L L L +N+L LPD + L + NN L P + +L L+ L GN ++ P
Sbjct: 3 LQYFPEQILELTQLQVLNLSGNHITNFPYRFFMLRFLTELYLRNDFLEFLPAQVCTLVQLEVLDLANNFIRTLPYSSGHLTRLRWLNLQNNQITNLPSSLADMNGLCYLNLEANELKIFPEEVSQLSRLRVLHLNSNNLRALPESFKLLNHLRILYLKDNKLRVLPDWFASFHCLAYLSMENNDLVCFPGEISKLTSLE------VLILSGNSIRELP 214 HSP 3 Score: 73.1738 bits (178), Expect = 6.303e-15 Identity = 53/177 (29.94%), Postives = 95/177 (53.67%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNN 649
++ L LQ ++++P L ++ L L++ EA +L+ P + +L L++L L++N+LR +P+ LL +L + L +N L LP+ + L L + NN FP I ++ S+E S N R +P SI+ L +L+ L L N++ LP + +L +++ L+L N
Sbjct: 85 LRWLNLQNNQITNLPSSLADMNGLCYLNL----EAN---ELKIFPEEVSQLSRLRVLHLNSNNLRALPESFKLLNHLRILYLKDNKLRVLPDWFASFHCLAYLSMENNDLVCFPGEISKLTSLEVLILSGNSIRELPDSIKELVNLKELFLGRNKIRKLPPSITKLEKLQVLYLQEN 254 HSP 4 Score: 70.8626 bits (172), Expect = 4.965e-14 Identity = 61/219 (27.85%), Postives = 108/219 (49.32%), Query Frame = 2
Query: 236 KLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQF-------------GRLKLL-DW--SWHYTS-TTLDGNPLQHPPLDICKKGADEIEKYFKKMYGSSVVEVPAA 841
KLQ P I +L L++L L N + + P +L L + L N+ L LP ++ L +L L +ANN T P + + + + +N ++P S+ ++ L L L N+L+ P+E+ +L ++R L L +N L LP+ F +L++L DW S+H + +++ N L P +I K + E+ + G+S+ E+P +
Sbjct: 2 KLQYFPEQILELTQLQVLNLSGNHITNFPYRFFMLRFLTELYLRNDFLEFLPAQVCTLVQLEVLDLANNFIRTLPYSSGHLTRLRWLNLQNNQITNLPSSLADMNGLCYLNLEANELKIFPEEVSQLSRLRVLHLNSNNLRALPESFKLLNHLRILYLKDNKLRVLPDWFASFHCLAYLSMENNDLVCFPGEISKLTSLEV----LILSGNSIRELPDS 216
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Nematostella
Match: EDO33460 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SS67]) HSP 1 Score: 86.2705 bits (212), Expect = 2.232e-18 Identity = 63/211 (29.86%), Postives = 109/211 (51.66%), Query Frame = 2
Query: 128 LKLQGKDLSSVPPELFNLLDLE--VLDMSPEREAGLYY-----------------KLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSME--FFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLD 697
L L L ++PP+L L++L+ +L+ +P A L + P + L NL L L NDL VP+ + L+++L+R+ LS+N++T L + I +L L+++ N+ + P +C+++ ++ F + ++ F +P I L +LE M NQLE +P+ LC I++R L L +N+L LP+ L LD
Sbjct: 125 LDLSDNCLETIPPQLRRLVNLQTLILNNNPLLHAQLRQLPSLSQLHTLHLRNTQRTIMNFPNKLEGLANLADLDLSHNDLPRVPEPVYLISSLKRVNLSHNAITELSSLIDTWTQLEHLNVSRNQLTSLPVALCKLVKIKRLFLNGNNINFEGLPTGIGKLYNLEVFMAAYNQLECIPEGLCRCIKLRKLILHSNRLFTLPEGIHFLTNLD 335 HSP 2 Score: 49.6766 bits (117), Expect = 1.408e-6 Identity = 34/115 (29.57%), Postives = 57/115 (49.57%), Query Frame = 2
Query: 338 LTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRS--VPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQF 676
++NL + L+ L TLP+E+ +L KL L + NK + + + +A +N ++ +P I L+ L T+ NQL +P EL + L L NNK++ +P Q
Sbjct: 1 MSNLRWLKLNKAGLETLPDELSHLPKLEHLSVKENKLNNIHGDLSTLKHLRVINARNNELKNSGIPGDIFGLEDLLTVDFSYNQLHEVPPELENAKALIVLSLSNNKISVIPNQL 115
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Nematostella
Match: EDO46974 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNR2]) HSP 1 Score: 83.1889 bits (204), Expect = 1.130e-17 Identity = 68/220 (30.91%), Postives = 108/220 (49.09%), Query Frame = 2
Query: 110 FYGMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDICK 769
++ L+L+ L +P + L +LE LD+ + E+P+ +G LLNL L +D+N ++ + EIGLL L + +S N L LP EI++L+ L L+++NN PE I + ++ +N +P SI L LE L+L N+L LP L L ++R L + N L +P + G + T +L N L H P I +
Sbjct: 139 LISLRILELRENHLRVLPKSMSQLKNLERLDIGNN-------EFTELPMVVGCLLNLTELWMDSNAIKELRPEIGLLRRLMFLDVSKNRLEWLPPEIESLQSLTDLYLSNNLLIEIPEQIGALGKLQTLKLEENHLGELPNSIGKLVELEELILTCNELVSLPPSLGYLRKLRVLNIDENFLESIPSELGSCTAM------TILSLRDNRLVHLPDSIGR 345 HSP 2 Score: 81.6481 bits (200), Expect = 3.454e-17 Identity = 66/206 (32.04%), Postives = 98/206 (47.57%), Query Frame = 2
Query: 95 TEDPLFYG----MKKLKLQGKDLSSVPPELFNLLDLEVLDMS--------PEREA-----GLYYK---LQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNK 652
TE P+ G + +L + + + PE+ L L LD+S PE E+ LY L E+P IG L L+ L L+ N L +P IG L LE + L+ N L +LP + L+KLR L+I N E+ P + +M DN +P SI + L+ + L N+LE LP +L+ ++ LWL N+
Sbjct: 176 TELPMVVGCLLNLTELWMDSNAIKELRPEIGLLRRLMFLDVSKNRLEWLPPEIESLQSLTDLYLSNNLLIEIPEQIGALGKLQTLKLEENHLGELPNSIGKLVELEELILTCNELVSLPPSLGYLRKLRVLNIDENFLESIPSELGSCTAMTILSLRDNRLVHLPDSIGRMPKLQVINLASNRLEYLPYSFHKLVSLKALWLSENQ 381 HSP 3 Score: 76.2554 bits (186), Expect = 2.358e-15 Identity = 56/170 (32.94%), Postives = 86/170 (50.59%), Query Frame = 2
Query: 248 VPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLP----------------NEIKN-------LKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLK 688
+P + G+L++L+IL L N LR +PK + L NLER+ + NN T LP N IK L++L L ++ N+ E P I + S+ S+N+ +P+ I L L+TL L EN L LP+ + +L+++ L L N+L LP G L+
Sbjct: 132 LPGNFGRLISLRILELRENHLRVLPKSMSQLKNLERLDIGNNEFTELPMVVGCLLNLTELWMDSNAIKELRPEIGLLRRLMFLDVSKNRLEWLPPEIESLQSLTDLYLSNNLLIEIPEQIGALGKLQTLKLEENHLGELPNSIGKLVELEELILTCNELVSLPPSLGYLR 301 HSP 4 Score: 73.9442 bits (180), Expect = 1.545e-14 Identity = 50/135 (37.04%), Postives = 72/135 (53.33%), Query Frame = 2
Query: 293 LDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLD 697
LD N LR +P+ + L NL+ + LS+N LT LP+ + NL LR L + N PE I +++ DAS N +P++ +L +L L L + L+ LP LI +R L L N L LPK +LK L+
Sbjct: 32 LDANQLRDLPRGLFNLQNLQVLGLSDNELTILPSVLSNLVNLRILDFSKNGIIDIPETIKHCKNLQEIDASVNPIGKIPETFCHLANLTHLYLNDAFLDFLPGNFGRLISLRILELRENHLRVLPKSMSQLKNLE 166 HSP 5 Score: 73.559 bits (179), Expect = 1.822e-14 Identity = 56/199 (28.14%), Postives = 98/199 (49.25%), Query Frame = 2
Query: 116 GMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFG---RLKLLDWS 703
++++ L L +P LFNL +L+VL +S +L +P + L+NL+IL N + +P+ I NL+ I S N + +P +L L L++ + + P ++S+ + +N R +PKS+ LK+LE L + N+ LP + L+ + LW+ +N + +L + G RL LD S
Sbjct: 26 ALEEVYLDANQLRDLPRGLFNLQNLQVLGLSDN-------ELTILPSVLSNLVNLRILDFSKNGIIDIPETIKHCKNLQEIDASVNPIGKIPETFCHLANLTHLYLNDAFLDFLPGNFGRLISLRILELRENHLRVLPKSMSQLKNLERLDIGNNEFTELPMVVGCLLNLTELWMDSNAIKELRPEIGLLRRLMFLDVS 217 HSP 6 Score: 72.7886 bits (177), Expect = 3.152e-14 Identity = 58/197 (29.44%), Postives = 96/197 (48.73%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGL-YYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSW 706
M L+L+ +L++V +LF + + L+ E L +L+++P + L NL++L L N+L +P + L NL + S N + +P IK+ K L+ + + N PE C + ++ +D +P + L SL L L EN L LP + +L + L +GNN+ T+LP G L L W
Sbjct: 1 MSVLELRHSNLTTVSHDLFKSKEGKALE-----EVYLDANQLRDLPRGLFNLQNLQVLGLSDNELTILPSVLSNLVNLRILDFSKNGIIDIPETIKHCKNLQEIDASVNPIGKIPETFCHLANLTHLYLNDAFLDFLPGNFGRLISLRILELRENHLRVLPKSMSQLKNLERLDIGNNEFTELPMVVGCLLNLTELW 192 HSP 7 Score: 70.4774 bits (171), Expect = 1.934e-13 Identity = 66/207 (31.88%), Postives = 98/207 (47.34%), Query Frame = 2
Query: 116 GMKKLKLQGKDLSSVPPELFNLLDLEVLDMS-------PEREAGLYYKLQEVPLS---IGK-------LLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRL 685
++ L L +L+ +P L NL++L +LD S PE LQE+ S IGK L NL L L+ L +P G L +L + L N L LP + LK L L I NN+F P ++ +L++ N + + I L+ L L + +N+LE LP E+ L + L+L NN L ++P+Q G L
Sbjct: 49 NLQVLGLSDNELTILPSVLSNLVNLRILDFSKNGIIDIPETIKHCK-NLQEIDASVNPIGKIPETFCHLANLTHLYLNDAFLDFLPGNFGRLISLRILELRENHLRVLPKSMSQLKNLERLDIGNNEFTELPMVVGCLLNLTELWMDSNAIKELRPEIGLLRRLMFLDVSKNRLEWLPPEIESLQSLTDLYLSNNLLIEIPEQIGAL 254
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Medaka
Match: mfhas1 (malignant fibrous histiocytoma amplified sequence 1 [Source:NCBI gene;Acc:101173528]) HSP 1 Score: 100.908 bits (250), Expect = 9.835e-23 Identity = 71/243 (29.22%), Postives = 116/243 (47.74%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLD-WSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFKKMYGSSVVEVPAAK 844
++ L LS P E+ L LE LD+S R L P +I +L ++K+L L + + +P+ L NLE + L N L+ LP L++L+ +++++N+ + FP+ + + +E S N VP+ I L L L L N + LPD + +L + L L N + LP FG+L ++ W + NPL PP ++C KG I Y +++ S + P K
Sbjct: 179 LRALDADHNQLSQFPVEILALGQLEELDLSGNRFVAL-------PANIWRLTSIKVLWLSSLRMASLPETFCRLQNLESLMLDGNRLSALPPSFGLLQRLKMMNLSSNQLQVFPQALLGVCGLEELYLSRNRLSHVPEEISQLGRLVNLWLDNNSITRLPDSIVDLENLEELVLQGNHIAVLPDNFGKLSRVNIWK-------VKDNPLIQPPYEVCMKGIPYIALYQQELAQSQLAVKPRLK 407 HSP 2 Score: 90.1225 bits (222), Expect = 3.180e-19 Identity = 63/198 (31.82%), Postives = 102/198 (51.52%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFG---RLKLLDWS 703
++ L+L+ ++ P L L L LDMS + L+ + +G+L LK L + N ++ +P +IG L LE + +S N L LP +L +LR+L +N+ FP I + +E D S N F ++P +I L S++ L L ++ LP+ C L + L L N+L+ LP FG RLK+++ S
Sbjct: 87 LRVLELRRNKFTAAPRVLCELGQLVELDMS-------HNCLRTLSEGLGQLRALKKLCVSHNKIQSLPAQIGALQALEELDISFNLLHGLPRSFSSLTRLRALDADHNQLSQFPVEILALGQLEELDLSGNRFVALPANIWRLTSIKVLWLSSLRMASLPETFCRLQNLESLMLDGNRLSALPPSFGLLQRLKMMNLS 277 HSP 3 Score: 78.5666 bits (192), Expect = 2.008e-15 Identity = 58/198 (29.29%), Postives = 97/198 (48.99%), Query Frame = 2
Query: 116 GMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLN-LKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSW 706
G+++L L ++ V PE ++ ++E L++ LQE+P +G LN L++L L N P+ + L L + +S+N L TL + L+ L+ L +++NK ++ P I + ++E D S N+ +P+S +L L L NQL P E+ L Q+ L L N+ LP RL + W
Sbjct: 41 GLRQLTLCAQNQQLVLPE--DISEVEALNLGNN-------SLQELPEELGSSLNKLRVLELRRNKFTAAPRVLCELGQLVELDMSHNCLRTLSEGLGQLRALKKLCVSHNKIQSLPAQIGALQALEELDISFNLLHGLPRSFSSLTRLRALDADHNQLSQFPVEILALGQLEELDLSGNRFVALPANIWRLTSIKVLW 229
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Medaka
Match: LRRC10B (leucine rich repeat containing 10B [Source:NCBI gene;Acc:101169357]) HSP 1 Score: 97.4413 bits (241), Expect = 4.233e-22 Identity = 73/220 (33.18%), Postives = 114/220 (51.82%), Query Frame = 2
Query: 95 TEDPLFYGMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPP 754
E+ L G L L + +P +++LL LE L + L+ +P I +L +L+IL LD N + VP + LTNL R+ L +N L +LP E+KNL+ LR L + +N F+ FP+ + ++ ++ DN +++P + +++L L LY N+ E P L + + L + NKLT+LP RLK S H S D NP+ PP
Sbjct: 43 VEELLESGDPVLDLSYRKFKRLPLRVYDLLYLEKLYVCGN-------SLRTLPERITQLQDLRILALDFNKIEDVPLPVCQLTNLTRLYLGSNRLMSLPPEVKNLQNLRCLWMESNYFQMFPKELYDLPHLKSLQMGDNRLKALPSDLCRMEALTGLWLYGNRFETFPTVLLRMEGLEILDMDRNKLTELP-SLKRLK----SLHLFS--YDHNPITAPP 248
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Medaka
Match: lrrc39 (leucine rich repeat containing 39 [Source:NCBI gene;Acc:101158344]) HSP 1 Score: 95.9005 bits (237), Expect = 6.213e-22 Identity = 58/184 (31.52%), Postives = 103/184 (55.98%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALS-NNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLP 667
+++ ++ L +P + + +L VLD+S + E+P IG+L LK L+L N ++ VP+E+G +LER+ LS N L+ LP++ +NL +L+ L ++ N F P+ I + ++E+ D N + +P+ I +++L TL L N LE LPD + + + L L +N+L +P
Sbjct: 81 VQEWQIHRTGLQKIPHFIPSFQNLLVLDLS-------RNSITEIPKQIGELTRLKELLLSYNRIQSVPEELGGCESLERLELSMNRDLSELPDQFRNLTRLQHLDLSMNCFSFIPDCIVALPALEWLDIGGNCLQHLPEDIHKMENLHTLWLQRNDLEKLPDNISRMASLDTLVLSSNRLRDIP 257 HSP 2 Score: 51.9878 bits (123), Expect = 3.874e-7 Identity = 37/133 (27.82%), Postives = 69/133 (51.88%), Query Frame = 2
Query: 116 GMKKLKLQ-GKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDN 511
+++L+L +DLS +P + NL L+ LD+S +P I L L+ L + N L+H+P++I + NL + L N L LP+ I + L +L +++N+ P ++ ++ ++ F + DN
Sbjct: 149 SLERLELSMNRDLSELPDQFRNLTRLQHLDLS-------MNCFSFIPDCIVALPALEWLDIGGNCLQHLPEDIHKMENLHTLWLQRNDLEKLPDNISRMASLDTLVLSSNRLRDIPPLMEDMSNLRFVNFRDN 274
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Medaka
Match: lrrc39 (leucine rich repeat containing 39 [Source:NCBI gene;Acc:101158344]) HSP 1 Score: 95.5153 bits (236), Expect = 7.916e-22 Identity = 58/184 (31.52%), Postives = 103/184 (55.98%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALS-NNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLP 667
+++ ++ L +P + + +L VLD+S + E+P IG+L LK L+L N ++ VP+E+G +LER+ LS N L+ LP++ +NL +L+ L ++ N F P+ I + ++E+ D N + +P+ I +++L TL L N LE LPD + + + L L +N+L +P
Sbjct: 88 VQEWQIHRTGLQKIPHFIPSFQNLLVLDLS-------RNSITEIPKQIGELTRLKELLLSYNRIQSVPEELGGCESLERLELSMNRDLSELPDQFRNLTRLQHLDLSMNCFSFIPDCIVALPALEWLDIGGNCLQHLPEDIHKMENLHTLWLQRNDLEKLPDNISRMASLDTLVLSSNRLRDIP 264 HSP 2 Score: 51.6026 bits (122), Expect = 4.841e-7 Identity = 35/123 (28.46%), Postives = 63/123 (51.22%), Query Frame = 2
Query: 143 KDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDN 511
+DLS +P + NL L+ LD+S +P I L L+ L + N L+H+P++I + NL + L N L LP+ I + L +L +++N+ P ++ ++ ++ F + DN
Sbjct: 166 RDLSELPDQFRNLTRLQHLDLS-------MNCFSFIPDCIVALPALEWLDIGGNCLQHLPEDIHKMENLHTLWLQRNDLEKLPDNISRMASLDTLVLSSNRLRDIPPLMEDMSNLRFVNFRDN 281
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Medaka
Match: lrrc7 (leucine rich repeat containing 7 [Source:NCBI gene;Acc:101170832]) HSP 1 Score: 97.8265 bits (242), Expect = 1.008e-21 Identity = 60/199 (30.15%), Postives = 105/199 (52.76%), Query Frame = 2
Query: 110 FYGMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSW 706
+ +K+L L L ++P + L L LD++ R ++ + + L+ L+L +N L+H+P IG+L L + + +N LT+LP+ I +L L + N+ E+ P I + S+ F A +N +P+ I N +++ + L N+LE LPDE+ ++ ++R L L +N+L LP F +LK L W
Sbjct: 219 IHNLKELWLDNNSLQTIPGSIGKLRQLRYLDLAKNR-------IETLDSDVSGCEALEDLLLSSNMLQHLPDSIGMLKKLTTLKVDDNQLTSLPHTIGSLSLLEEFDCSCNELESLPPTIGYLHSLRTFAADENFLTELPREIGNCRNVTVMSLRSNKLEFLPDEIGQMTKLRVLNLSDNRLKNLPFTFTKLKDLAALW 410 HSP 2 Score: 90.1225 bits (222), Expect = 4.124e-19 Identity = 50/153 (32.68%), Postives = 86/153 (56.21%), Query Frame = 2
Query: 239 LQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLD 697
L+ +P + G+L L+IL L N L+ +PK I LT LER+ L +N + +P ++ + L+ L + NN +T P I ++ + + D + N ++ + ++LE L+L N L+ LPD + L ++ L + +N+LT LP G L LL+
Sbjct: 163 LEYLPANFGRLSKLRILELRENHLKTMPKSIHRLTQLERLDLGSNEFSEVPEVLEQIHNLKELWLDNNSLQTIPGSIGKLRQLRYLDLAKNRIETLDSDVSGCEALEDLLLSSNMLQHLPDSIGMLKKLTTLKVDDNQLTSLPHTIGSLSLLE 315 HSP 3 Score: 80.1073 bits (196), Expect = 6.687e-16 Identity = 54/152 (35.53%), Postives = 80/152 (52.63%), Query Frame = 2
Query: 239 LQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLL 694
L+ +P SI +L L+ L L +N+ VP+ + + NL+ + L NNSL T+P I L++LR L +A N+ ET + ++E S NM + +P SI LK L TL + +NQL LP + L + N+L LP G L L
Sbjct: 186 LKTMPKSIHRLTQLERLDLGSNEFSEVPEVLEQIHNLKELWLDNNSLQTIPGSIGKLRQLRYLDLAKNRIETLDSDVSGCEALEDLLLSSNMLQHLPDSIGMLKKLTTLKVDDNQLTSLPHTIGSLSLLEEFDCSCNELESLPPTIGYLHSL 337 HSP 4 Score: 79.7221 bits (195), Expect = 9.017e-16 Identity = 55/194 (28.35%), Postives = 93/194 (47.94%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDW 700
+++L L + +P +LFN L+ L M P+ + L +P +I L+NLK L + N ++ P I L + S N +T LP+ L L L + + E P + + + +N +++PKSI L LE L L N+ +P+ L ++ ++ LWL NN L +P G+L+ L +
Sbjct: 61 LEELYLDANQIEELPKQLFNCQALKKLSM-PDND------LSNLPTTIASLVNLKELDISKNGIQEFPDNIKCCKGLSVVEASVNPITKLPDGFTQLLNLTQLFLNDAFLEYLPANFGRLSKLRILELRENHLKTMPKSIHRLTQLERLDLGSNEFSEVPEVLEQIHNLKELWLDNNSLQTIPGSIGKLRQLRY 247 HSP 5 Score: 79.337 bits (194), Expect = 1.525e-15 Identity = 55/190 (28.95%), Postives = 93/190 (48.95%), Query Frame = 2
Query: 119 MKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLK 688
++ L+L+ L ++P + L LE LD+ + EVP + ++ NLK L LD N L+ +P IG L L + L+ N + TL +++ + L L +++N + P+ I + + DN S+P +I +L LE N+LE LP + L +R N LT+LP++ G +
Sbjct: 176 LRILELRENHLKTMPKSIHRLTQLERLDLG-------SNEFSEVPEVLEQIHNLKELWLDNNSLQTIPGSIGKLRQLRYLDLAKNRIETLDSDVSGCEALEDLLLSSNMLQHLPDSIGMLKKLTTLKVDDNQLTSLPHTIGSLSLLEEFDCSCNELESLPPTIGYLHSLRTFAADENFLTELPREIGNCR 358 HSP 6 Score: 75.8702 bits (185), Expect = 2.092e-14 Identity = 54/183 (29.51%), Postives = 91/183 (49.73%), Query Frame = 2
Query: 116 GMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQL 664
+KKL + DLS++P + +L++L+ LD+S +QE P +I L ++ N + +P L NL ++ L++ L LP L KLR L + N +T P+ I + +E D N F VP+ + + +L+ L L N L+ +P + +L Q+R L L N++ L
Sbjct: 83 ALKKLSMPDNDLSNLPTTIASLVNLKELDIS-------KNGIQEFPDNIKCCKGLSVVEASVNPITKLPDGFTQLLNLTQLFLNDAFLEYLPANFGRLSKLRILELRENHLKTMPKSIHRLTQLERLDLGSNEFSEVPEVLEQIHNLKELWLDNNSLQTIPGSIGKLRQLRYLDLAKNRIETL 258 HSP 7 Score: 69.707 bits (169), Expect = 2.017e-12 Identity = 50/178 (28.09%), Postives = 85/178 (47.75%), Query Frame = 2
Query: 236 KLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDICK 769
+++E+P + LK L + NDL ++P I L NL+ + +S N + P+ IK K L + + N P+ ++L++ +D +P + L L L L EN L+ +P + L Q+ L LG+N+ +++P+ ++ L W LD N LQ P I K
Sbjct: 70 QIEELPKQLFNCQALKKLSMPDNDLSNLPTTIASLVNLKELDISKNGIQEFPDNIKCCKGLSVVEASVNPITKLPDGFTQLLNLTQLFLNDAFLEYLPANFGRLSKLRILELRENHLKTMPKSIHRLTQLERLDLGSNEFSEVPEVLEQIHNLKELW------LDNNSLQTIPGSIGK 241
BLAST of Leucine-rich repeat-containing protein 57 vs. Planmine SMEST
Match: SMESG000037709.1 (SMESG000037709.1) HSP 1 Score: 580.482 bits (1495), Expect = 0.000e+0 Identity = 303/304 (99.67%), Postives = 304/304 (100.00%), Query Frame = 2
Query: 53 MADKKNKSLRMMVDTEDPLFYGMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFKKMYGSSVVEVPAAKGGTSNTLNFDVDAMRYLRRXXXXXXXXXXXXXXXLHASPH 964
MADKKNKSLRMMVDTEDPLFYGMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQ+RCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFKKMYGSSVVEVPAAKGGTSNTLNFDVDAMRYLRRGSSPGPPPEMMAPGGLHASPH
Sbjct: 1 MADKKNKSLRMMVDTEDPLFYGMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQLRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFKKMYGSSVVEVPAAKGGTSNTLNFDVDAMRYLRRGSSPGPPPEMMAPGGLHASPH 304
BLAST of Leucine-rich repeat-containing protein 57 vs. Planmine SMEST
Match: SMESG000029655.1 (SMESG000029655.1) HSP 1 Score: 90.8929 bits (224), Expect = 1.015e-19 Identity = 63/218 (28.90%), Postives = 111/218 (50.92%), Query Frame = 2
Query: 104 PLFYGMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQF----GRLKLLDWSWHYTSTTLDGNPLQ 745
P+ +++ LQ +S P EL L+VLD+ R ++ +P + +L NL++L+L +N + +P + L NL+ + L N+++ LP I L++L +L++A NK + PE +C SM D N +P+S+ NL++L L + NQ+ +P L ++ ++ + N + LP QF G L ++ S + T G P Q
Sbjct: 149 PVLMQLERCYLQQNSISVFPVELSKCTGLKVLDLRSNR-------IEIIPECLFELQNLELLILSSNRIESIPDSVQKLQNLKHLGLDKNNISRLPPVIGKLQRLMNLNLAFNKIDELPEELCNCASMRDLDVMHNRLTELPESLGNLQNLVRLNIRNNQITKIPISLVKVKNLKEFIMEQNCVENLPDQFLSNLGNLDNVNLSRNAFKTFPTGGPNQ 359 HSP 2 Score: 75.485 bits (184), Expect = 1.107e-14 Identity = 57/175 (32.57%), Postives = 89/175 (50.86%), Query Frame = 2
Query: 293 LDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNN-KLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFKKMYG 814
L +N L +P EIG L NL+++ LS+N + LP I NL L L + +N+ E+ P+ I + S+ + + N +S+P SI LKSL L L EN L +P E+ E+ + L L NN L LP++ L +L+ L++ P + +G I + K+Y
Sbjct: 416 LSSNQLSIIPPEIGALVNLQKLHLSSNHIKKLPPTIGNLNALVLLELDDNQIESLPDEIGNLQSVVDLNLTTNELKSLPASIGKLKSLMKLRLAENDLRIVPPEIGEMSSLTELHLKNNVNLDNLPEE------LTLCEKLMILSLENCGLRNIPEQVKSQGVRIIVYFLSKVYA 584 HSP 3 Score: 61.6178 bits (148), Expect = 4.046e-10 Identity = 57/185 (30.81%), Postives = 86/185 (46.49%), Query Frame = 2
Query: 125 KLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYEN-QLEGLPDELCELIQMRCLWLGNNKLTQLPKQF 676
+L L LS +PPE+ L++L+ L +S ++++P +IG L L +L LD N + +P EIG L ++ + L+ N L +LP I LK L L +A +N R VP I + SL L L N L+ LP+EL ++ L L N L +P+Q
Sbjct: 413 ELDLSSNQLSIIPPEIGALVNLQKLHLSSNH-------IKKLPPTIGNLNALVLLELDDNQIESLPDEIGNLQSVVDLNLTTNELKSLPASIGKLKSLMKLRLA-----------------------ENDLRIVPPEIGEMSSLTELHLKNNVNLDNLPEELTLCEKLMILSLENCGLRNIPEQV 567 HSP 4 Score: 59.3066 bits (142), Expect = 1.902e-9 Identity = 58/243 (23.87%), Postives = 105/243 (43.21%), Query Frame = 2
Query: 116 GMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKE-IGLLTNLERIALSNNSLTT-------------------------------------------------LPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLL 694
M+ L + L+ +P L NL +L L++ ++ ++P+S+ K+ NLK +++ N + ++P + + L NL+ + LS N+ T +PN++ L L +++N+ P I +++++ S N + +P +I NL +L L L +NQ+E LPDE+ L + L L N+L LP G+LK L
Sbjct: 268 SMRDLDVMHNRLTELPESLGNLQNLVRLNIR-------NNQITKIPISLVKVKNLKEFIMEQNCVENLPDQFLSNLGNLDNVNLSRNAFKTFPTGGPNQFATTMSLNMSNNHIDCIPMGIFSVSKHLSILNLRGNEICTLIPNDVVTWTTLVELDLSSNQLSIIPPEIGALVNLQKLHLSSNHIKKLPPTIGNLNALVLLELDDNQIESLPDEIGNLQSVVDLNLTTNELKSLPASIGKLKSL 503
BLAST of Leucine-rich repeat-containing protein 57 vs. Planmine SMEST
Match: SMESG000029655.1 (SMESG000029655.1) HSP 1 Score: 90.8929 bits (224), Expect = 1.107e-19 Identity = 63/218 (28.90%), Postives = 111/218 (50.92%), Query Frame = 2
Query: 104 PLFYGMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQF----GRLKLLDWSWHYTSTTLDGNPLQ 745
P+ +++ LQ +S P EL L+VLD+ R ++ +P + +L NL++L+L +N + +P + L NL+ + L N+++ LP I L++L +L++A NK + PE +C SM D N +P+S+ NL++L L + NQ+ +P L ++ ++ + N + LP QF G L ++ S + T G P Q
Sbjct: 158 PVLMQLERCYLQQNSISVFPVELSKCTGLKVLDLRSNR-------IEIIPECLFELQNLELLILSSNRIESIPDSVQKLQNLKHLGLDKNNISRLPPVIGKLQRLMNLNLAFNKIDELPEELCNCASMRDLDVMHNRLTELPESLGNLQNLVRLNIRNNQITKIPISLVKVKNLKEFIMEQNCVENLPDQFLSNLGNLDNVNLSRNAFKTFPTGGPNQ 368 HSP 2 Score: 75.8702 bits (185), Expect = 1.031e-14 Identity = 57/175 (32.57%), Postives = 89/175 (50.86%), Query Frame = 2
Query: 293 LDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNN-KLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDICKKGADEIEKYFKKMYG 814
L +N L +P EIG L NL+++ LS+N + LP I NL L L + +N+ E+ P+ I + S+ + + N +S+P SI LKSL L L EN L +P E+ E+ + L L NN L LP++ L +L+ L++ P + +G I + K+Y
Sbjct: 425 LSSNQLSIIPPEIGALVNLQKLHLSSNHIKKLPPTIGNLNALVLLELDDNQIESLPDEIGNLQSVVDLNLTTNELKSLPASIGKLKSLMKLRLAENDLRIVPPEIGEMSSLTELHLKNNVNLDNLPEE------LTLCEKLMILSLENCGLRNIPEQVKSQGVRIIVYFLSKVYA 593 HSP 3 Score: 61.6178 bits (148), Expect = 4.008e-10 Identity = 57/185 (30.81%), Postives = 86/185 (46.49%), Query Frame = 2
Query: 125 KLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYEN-QLEGLPDELCELIQMRCLWLGNNKLTQLPKQF 676
+L L LS +PPE+ L++L+ L +S ++++P +IG L L +L LD N + +P EIG L ++ + L+ N L +LP I LK L L +A +N R VP I + SL L L N L+ LP+EL ++ L L N L +P+Q
Sbjct: 422 ELDLSSNQLSIIPPEIGALVNLQKLHLSSNH-------IKKLPPTIGNLNALVLLELDDNQIESLPDEIGNLQSVVDLNLTTNELKSLPASIGKLKSLMKLRLA-----------------------ENDLRIVPPEIGEMSSLTELHLKNNVNLDNLPEELTLCEKLMILSLENCGLRNIPEQV 576 HSP 4 Score: 59.6918 bits (143), Expect = 1.850e-9 Identity = 58/243 (23.87%), Postives = 105/243 (43.21%), Query Frame = 2
Query: 116 GMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKE-IGLLTNLERIALSNNSLTT-------------------------------------------------LPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLL 694
M+ L + L+ +P L NL +L L++ + + ++P+S+ K+ NLK +++ N + ++P + + L NL+ + LS N+ T +PN++ L L +++N+ P I +++++ S N + +P +I NL +L L L +NQ+E LPDE+ L + L L N+L LP G+LK L
Sbjct: 277 SMRDLDVMHNRLTELPESLGNLQNLVRLNIRNNQ-------ITKIPISLVKVKNLKEFIMEQNCVENLPDQFLSNLGNLDNVNLSRNAFKTFPTGGPNQFATTMSLNMSNNHIDCIPMGIFSVSKHLSILNLRGNEICTLIPNDVVTWTTLVELDLSSNQLSIIPPEIGALVNLQKLHLSSNHIKKLPPTIGNLNALVLLELDDNQIESLPDEIGNLQSVVDLNLTTNELKSLPASIGKLKSL 512
BLAST of Leucine-rich repeat-containing protein 57 vs. Planmine SMEST
Match: SMESG000007767.1 (SMESG000007767.1) HSP 1 Score: 84.7297 bits (208), Expect = 4.447e-18 Identity = 66/237 (27.85%), Postives = 120/237 (50.63%), Query Frame = 2
Query: 125 KLKLQGKDLSSVPPELFNLLDLEVLDMS-------PE-------REAGLYYKL-QEVPLSIGKLLNLKILMLDTNDLRHVPKEIGL-LTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDICKKGADEI 787
K L+ L +P ++ L DL+VLD+ P+ E + + L +E+P+ I L +LKIL+ N L ++ I + L LE + ++ N L ++P I N + LR LH ++N ++ PE + + +++ A N +P+S L L+ L+L++NQL LP+ + +++ +R L + N + +P + + L + +HY S L L P +C + DE+
Sbjct: 21 KFSLEKLKLDQIPFDISILNDLKVLDVQINLLNNLPDLSSIKNLTEFNISFNLFKEIPIQIQFLKSLKILICHHNQLSNIDYNIFIDLKKLEILNVNFNKLCSIPESISNCENLRKLHCSHNSLKSLPESLSQCKNLQEIHAGYNKITDIPESFGELIKLKILILHKNQLADLPENMADMVSLRVLDVAANNIQVMPSEVNEMSLSE--FHYESNPL----LNLEP--VCSRQIDEV 249
BLAST of Leucine-rich repeat-containing protein 57 vs. Planmine SMEST
Match: SMESG000016748.1 (SMESG000016748.1) HSP 1 Score: 84.3445 bits (207), Expect = 1.998e-17 Identity = 54/207 (26.09%), Postives = 102/207 (49.28%), Query Frame = 2
Query: 143 KDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDI 763
++L VP E++ D+E++++S K+ ++ I L L+ ++ N LR + + L+ + +SNN L +P EI NL L + ++NK + P I +L +++ + S N + +P+ I NLKSL+T ++ N++ +P + + ++ + NN++ LP + W + LDGN Q P I
Sbjct: 39 QNLYDVPKEIYFHPDVELINLSKN-------KISDLSDEIIALSKLRHFFVNGNMLRTINVNLFYARGLQSLDVSNNKLEVIPVEIANLGHLEYFNCSHNKLKALPLTIFGLLKLQYMNLSHNQIQDIPEEIGNLKSLQTFLINSNEIVLIPSSISTITSLKTIEASNNQMCHLP--------ISWVGSLKTLKLDGNQFQFIPSQI 230 HSP 2 Score: 67.781 bits (164), Expect = 5.126e-12 Identity = 46/193 (23.83%), Postives = 90/193 (46.63%), Query Frame = 2
Query: 116 GMKKLKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLL 694
+K LKL G +P ++++ +++ L ++ L+ +P+ + KL NL+ L L N + ++P E+G T L + N++T P + K L+I+ + + FP ++C + +N +P + +++ L + N E +P ++C L + L +N L Q+P LK L
Sbjct: 212 SLKTLKLDGNQFQFIPSQIYDCCEMKYLSLAKNY-------LKFIPIELVKLRNLRQLDLSFNSIEYIPCEMGYWTKLVDFNIHGNNITYFPQSLIANHKFVCLNISGCQLKEFPLLLCNCYDLMELRVGENELNELPDKFQLFCNMKYLFMNNNNFELIPLQVCLLSTLVELDFSHNFLWQVPPGIFSLKHL 397 HSP 3 Score: 65.0846 bits (157), Expect = 3.376e-11 Identity = 43/139 (30.94%), Postives = 70/139 (50.36%), Query Frame = 2
Query: 278 LKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLL 694
LK + +L VPKEI ++E I LS N ++ L +EI L KLR + N T + ++ D S+N +P I NL LE N+L+ LP + L++++ + L +N++ +P++ G LK L
Sbjct: 31 LKCFVYVMQNLYDVPKEIYFHPDVELINLSKNKISDLSDEIIALSKLRHFFVNGNMLRTINVNLFYARGLQSLDVSNNKLEVIPVEIANLGHLEYFNCSHNKLKALPLTIFGLLKLQYMNLSHNQIQDIPEEIGNLKSL 169 HSP 4 Score: 59.6918 bits (143), Expect = 1.910e-9 Identity = 44/172 (25.58%), Postives = 81/172 (47.09%), Query Frame = 2
Query: 278 LKILMLDTNDLRHVPKEIGLLTNLERIALSN---NSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMRCLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDICKKGADE 784
L+ + N P E+ + ++ ++ + +LP EIKNL +L L+++NN+F T P +I E+ +++ + ++N+ + +P ++ + K+LE + + NQL LP L L +NK+ DG+PL +PPL +C G E
Sbjct: 489 LRTIDFSNNKFTEFPVELCVHDSIRKLVFDQKEGTKIKSLPVEIKNLWRLAELNLSNNEFLTIPPVIMELENLKVLEMANNILKELPLNLSDAKNLENIDVRNNQLTELPFSLTTL---------SNKI--------------------KFKFDGSPLVNPPLIVCIGGNME 631 HSP 5 Score: 55.0694 bits (131), Expect = 5.784e-8 Identity = 58/241 (24.07%), Postives = 102/241 (42.32%), Query Frame = 2
Query: 128 LKLQGKDLSSVPPELFNLLDLEVLDMSPEREAGLYYKLQEVPLSIGKLLNLKILMLDTNDLRHVPKEIGLLTNLERIALSNNSLTTLPNEIKNLKKLRSLHIANNKFETFPEIICEILSMEFFDASDNMFRSVPKSIRNLKSLETLMLYENQLEGLPDELCELIQMR---CLWLGNNKLTQLPKQFGRLKLLDWSWHYTSTTLDGNPLQHPPLDICKKGADEIEK-YFKKMYGSSVVEVPA 838
L + G L P L N DL L + +L E+P N+K L ++ N+ +P ++ LL+ L + S+N L +P I +LK LR L+++ N FP E+ + + S N + SI + L L L N+L P + +L ++ + ++ K++ L+ +D+S N P+++C D I K F + G+ + +P
Sbjct: 308 LNISGCQLKEFPLLLCNCYDLMELRVGEN-------ELNELPDKFQLFCNMKYLFMNNNNFELIPLQVCLLSTLVELDFSHNFLWQVPPGIFSLKHLRKLNLSFNNILIFPGCTAELSYLSELNVSHNKISEICDSISWMTFLYYLDLSFNELSTFPSAIFQLRYLKYLNLSNNLLDNFSKTDKKWEELRTIDFS---------NNKFTEFPVELCVH--DSIRKLVFDQKEGTKIKSLPV 530 The following BLAST results are available for this feature:
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Leucine-rich repeat-containing protein 57 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Leucine-rich repeat-containing protein 57 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 3
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Leucine-rich repeat-containing protein 57 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Leucine-rich repeat-containing protein 57 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30020334 ID=SMED30020334|Name=Leucine-rich repeat-containing protein 57|organism=Schmidtea mediterranea sexual|type=transcript|length=1104bpback to top protein sequence of SMED30020334-orf-1 >SMED30020334-orf-1 ID=SMED30020334-orf-1|Name=SMED30020334-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=305bp MADKKNKSLRMMVDTEDPLFYGMKKLKLQGKDLSSVPPELFNLLDLEVLDback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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